# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RskA PF10099.9 KIR60544.1 - 0.019 15.2 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA tRNA-synt_1 PF00133.22 KIR60545.1 - 1.3e-191 638.0 0.0 7.8e-189 628.8 0.0 2.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIR60545.1 - 4.7e-41 140.3 0.0 7.5e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIR60545.1 - 1.8e-20 73.1 0.0 7.5e-06 24.9 0.0 4.0 4 0 0 4 4 4 4 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KIR60545.1 - 5.5e-15 55.4 3.3 1.2e-14 54.3 3.3 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 KIR60545.1 - 5.1e-07 29.4 0.1 8.9e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KIR60545.1 - 0.0075 15.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KIR60545.1 - 0.0097 14.9 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) DUF4233 PF14017.6 KIR60546.1 - 5.4e-21 74.9 17.2 6.2e-21 74.7 17.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4233) Glyoxalase PF00903.25 KIR60547.1 - 7.5e-12 45.5 0.0 1.7e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR60547.1 - 6.9e-09 36.5 0.6 3.1e-08 34.4 0.1 2.3 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIR60547.1 - 0.0091 16.3 0.0 0.32 11.3 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KIR60547.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Phage_holin_3_6 PF07332.11 KIR60547.1 - 0.71 9.9 9.5 1.4 9.0 9.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III NDK PF00334.19 KIR60548.1 - 4.1e-50 169.3 0.0 4.5e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ACT PF01842.25 KIR60548.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 ACT domain CMD PF02627.20 KIR60549.1 - 6.7e-18 64.5 4.7 9.1e-18 64.1 1.6 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Brucella_OMP2 PF05244.11 KIR60549.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Brucella outer membrane protein 2 PhoD PF09423.10 KIR60550.1 - 1.9e-76 257.4 0.0 2.3e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KIR60550.1 - 8e-18 64.8 0.6 2.1e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain tRNA-synt_1 PF00133.22 KIR60551.1 - 1.5e-181 604.7 0.0 2.1e-181 604.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIR60551.1 - 4e-27 95.1 0.0 7.8e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIR60551.1 - 1.3e-17 63.6 0.7 2.9e-07 29.6 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIR60551.1 - 0.0019 17.6 0.0 0.0047 16.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Acyltransferase PF01553.21 KIR60552.1 - 8.5e-23 80.5 0.0 1.1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF374 PF04028.13 KIR60552.1 - 0.04 13.5 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) DPRP PF04244.13 KIR60553.1 - 3.6e-34 118.6 0.0 5.3e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 Deoxyribodipyrimidine photo-lyase-related protein PHZA_PHZB PF03284.13 KIR60554.1 - 0.18 11.4 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Radical_SAM PF04055.21 KIR60555.1 - 6.4e-17 62.4 0.0 3.1e-16 60.2 0.0 2.2 2 1 1 3 3 3 1 Radical SAM superfamily B12-binding PF02310.19 KIR60555.1 - 0.00047 20.2 0.1 0.0013 18.8 0.1 1.7 1 0 0 1 1 1 1 B12 binding domain RNase_E_G PF10150.9 KIR60556.1 - 4e-104 347.8 0.0 5.4e-104 347.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 KIR60556.1 - 0.00052 20.3 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain PPP4R2 PF09184.11 KIR60556.1 - 5.3 6.5 8.9 9.4 5.7 8.9 1.4 1 0 0 1 1 1 0 PPP4R2 Ribosomal_L21p PF00829.21 KIR60558.1 - 7.6e-36 122.4 1.3 8.4e-36 122.3 1.3 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_L27 PF01016.19 KIR60559.1 - 5.6e-35 119.2 1.6 6.2e-35 119.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein GTP1_OBG PF01018.22 KIR60560.1 - 4.1e-50 169.4 10.7 5.9e-50 168.9 10.7 1.2 1 0 0 1 1 1 1 GTP1/OBG DUF1967 PF09269.11 KIR60560.1 - 7.5e-28 96.3 0.0 1.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) MMR_HSR1 PF01926.23 KIR60560.1 - 9e-23 80.5 0.0 1.5e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIR60560.1 - 2.7e-10 40.0 0.0 1.3e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KIR60560.1 - 0.00018 21.0 0.0 0.00036 20.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIR60560.1 - 0.0017 18.3 0.0 0.073 13.0 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KIR60560.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KIR60560.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Acetyltransf_1 PF00583.25 KIR60561.1 - 3.6e-15 56.2 0.1 4.3e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR60561.1 - 3.6e-12 46.5 0.0 4.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR60561.1 - 1.6e-11 44.2 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR60561.1 - 2.6e-05 24.1 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIR60561.1 - 4.7e-05 24.1 0.0 5.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR60561.1 - 0.0005 20.1 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KIR60561.1 - 0.0087 16.2 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIR60561.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PanZ PF12568.8 KIR60561.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 KIR60561.1 - 0.059 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF4383 PF14325.6 KIR60562.1 - 5.5e-40 136.5 19.8 6.3e-40 136.3 19.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF883 PF05957.13 KIR60563.1 - 0.0011 19.5 11.4 0.58 10.8 3.9 2.8 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) DUF3987 PF13148.6 KIR60563.1 - 0.014 14.4 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Phage_holin_3_6 PF07332.11 KIR60564.1 - 1.4e-29 102.4 4.7 1.6e-29 102.2 4.7 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III VirB3 PF05101.13 KIR60564.1 - 0.018 15.2 0.2 0.026 14.8 0.2 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein MtrG PF04210.13 KIR60564.1 - 0.14 12.1 1.0 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2615 PF11027.8 KIR60564.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF4330 PF14221.6 KIR60564.1 - 0.18 12.0 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF2207 PF09972.9 KIR60564.1 - 0.19 10.4 0.0 0.22 10.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3618 PF12277.8 KIR60565.1 - 7.9e-18 64.5 1.9 7.9e-18 64.5 1.9 5.0 4 1 1 5 5 5 1 Protein of unknown function (DUF3618) Apolipoprotein PF01442.18 KIR60565.1 - 2.6e-09 37.3 17.7 8.8e-05 22.5 9.7 2.2 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KIR60565.1 - 9.9e-08 32.5 24.1 0.00051 20.6 5.9 3.9 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KIR60565.1 - 0.0041 17.6 12.1 0.19 12.3 0.3 3.9 2 2 1 3 3 3 3 YtxH-like protein Gpr1_Fun34_YaaH PF01184.19 KIR60565.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family ApoLp-III PF07464.11 KIR60565.1 - 0.019 15.1 4.2 0.15 12.2 0.8 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FAM199X PF15814.5 KIR60565.1 - 0.059 12.4 2.1 0.083 11.9 2.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X Synuclein PF01387.17 KIR60565.1 - 0.1 12.8 7.9 1.3 9.2 2.9 2.6 1 1 1 2 2 2 0 Synuclein Phasin PF05597.11 KIR60565.1 - 0.31 11.0 12.2 0.75 9.8 4.2 3.5 2 2 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) WXG100 PF06013.12 KIR60565.1 - 0.32 11.2 10.1 0.18 12.1 0.5 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Chlorosome_CsmC PF11098.8 KIR60565.1 - 1 9.4 9.5 2.8 7.9 2.4 2.7 1 1 0 2 2 2 0 Chlorosome envelope protein C Atg14 PF10186.9 KIR60565.1 - 3.2 6.7 4.8 0.31 10.1 0.3 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAP160 PF07918.11 KIR60565.1 - 7.8 6.3 9.1 6 6.7 6.8 2.0 1 1 1 2 2 2 0 CAP160 repeat p450 PF00067.22 KIR60566.1 - 1.2e-12 47.4 0.1 1.8e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF397 PF04149.12 KIR60568.1 - 4.5e-14 52.3 0.2 5.2e-14 52.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Peptidase_M1 PF01433.20 KIR60569.1 - 1.3e-54 185.1 0.0 1.7e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KIR60569.1 - 2.3e-44 152.3 1.1 2.3e-44 152.3 1.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KIR60569.1 - 0.0023 18.2 0.0 0.0075 16.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M78 PF06114.13 KIR60569.1 - 0.043 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 IrrE N-terminal-like domain CTP_transf_like PF01467.26 KIR60570.1 - 1.8e-32 112.5 0.0 2.1e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like RsfS PF02410.15 KIR60571.1 - 2.2e-22 79.3 0.1 2.6e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation PAZ PF02170.22 KIR60571.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 PAZ domain His_Phos_1 PF00300.22 KIR60572.1 - 1.6e-54 184.5 5.1 1.8e-54 184.4 5.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) adh_short_C2 PF13561.6 KIR60573.1 - 7.3e-46 156.6 1.5 8.6e-46 156.4 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR60573.1 - 2.1e-35 122.0 0.1 2.7e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR60573.1 - 7.6e-11 42.2 0.5 1e-10 41.8 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR60573.1 - 5.7e-07 29.2 0.1 1.2e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR60573.1 - 0.00025 21.0 3.9 0.00043 20.2 3.9 1.4 1 1 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KIR60573.1 - 0.00045 20.5 0.1 0.00091 19.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KIR60573.1 - 0.0038 16.7 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR60573.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DNA_pol3_delta PF06144.13 KIR60574.1 - 5.5e-06 26.3 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 KIR60574.1 - 4.9e-05 23.3 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III Ribosomal_S20p PF01649.18 KIR60575.1 - 3.9e-28 97.9 16.8 4.3e-28 97.8 16.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 DUF4398 PF14346.6 KIR60575.1 - 0.0036 17.9 1.7 0.0036 17.9 1.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) SMBP PF16785.5 KIR60575.1 - 0.0061 16.8 2.2 0.0067 16.6 2.2 1.2 1 0 0 1 1 1 1 Small metal-binding protein DUF4878 PF12870.7 KIR60575.1 - 0.028 14.7 0.6 0.035 14.4 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4878) DUF4240 PF14024.6 KIR60576.1 - 3.2e-42 143.7 0.7 4.5e-42 143.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4240) GTP_EFTU PF00009.27 KIR60577.1 - 2.9e-51 173.8 0.0 4.3e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KIR60577.1 - 2.8e-49 165.8 0.4 5.4e-49 164.8 0.4 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KIR60577.1 - 7.2e-23 80.4 0.0 1.6e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIR60577.1 - 2.8e-07 30.8 3.5 5.7e-07 29.8 3.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIR60577.1 - 0.00018 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KIR60577.1 - 0.0002 21.4 0.0 0.00077 19.5 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KIR60577.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Transgly_assoc PF04226.13 KIR60578.1 - 0.014 15.7 9.7 0.014 15.7 9.7 2.2 2 0 0 2 2 2 0 Transglycosylase associated protein DUF983 PF06170.12 KIR60578.1 - 0.063 13.7 1.4 0.063 13.7 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF983) DUF1129 PF06570.11 KIR60578.1 - 2.6 7.5 4.8 3.3 7.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4231 PF14015.6 KIR60578.1 - 7 7.2 6.6 35 4.9 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Transgly_assoc PF04226.13 KIR60579.1 - 0.0063 16.7 11.9 0.0063 16.7 11.9 2.1 2 0 0 2 2 2 2 Transglycosylase associated protein DUF983 PF06170.12 KIR60579.1 - 0.02 15.3 1.3 0.02 15.3 1.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF983) PRD1_DD PF11087.8 KIR60579.1 - 0.051 13.3 2.1 0.051 13.3 2.1 2.8 2 1 1 3 3 3 0 PRD1 phage membrane DNA delivery Tmemb_170 PF10190.9 KIR60579.1 - 0.85 10.0 7.0 0.34 11.3 3.0 2.0 2 0 0 2 2 2 0 Putative transmembrane protein 170 DUF4231 PF14015.6 KIR60579.1 - 4 8.0 5.5 10 6.7 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) SBP_bac_1 PF01547.25 KIR60580.1 - 1.2e-45 156.8 26.4 1.8e-45 156.3 26.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR60580.1 - 7.2e-40 137.6 18.2 1.1e-39 137.0 18.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR60581.1 - 3.9e-17 62.6 17.5 3.9e-17 62.6 17.5 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MOSC PF03473.17 KIR60582.1 - 1.4e-20 73.7 0.0 1.9e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 KIR60582.1 - 3.8e-06 26.7 0.2 6.6e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 3-alpha domain PhyH PF05721.13 KIR60583.1 - 1.5e-16 61.3 0.3 2.3e-16 60.7 0.3 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.11 KIR60583.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain ECH_1 PF00378.20 KIR60584.1 - 3e-50 170.9 0.0 3.6e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR60584.1 - 1.7e-27 96.8 0.2 2.3e-27 96.4 0.2 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SPDY PF03771.16 KIR60584.1 - 1.9 8.5 5.7 4.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF317) DUF4870 PF09685.10 KIR60585.1 - 4.1e-26 91.2 4.0 4.8e-26 91.0 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) HrcA PF01628.21 KIR60586.1 - 4.6e-62 209.8 0.4 5.8e-62 209.5 0.4 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain HTH_DeoR PF08220.12 KIR60586.1 - 2.7e-06 27.0 0.0 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KIR60586.1 - 0.00088 19.2 0.0 0.0025 17.7 0.0 1.8 1 0 0 1 1 1 1 HTH domain HrcA_DNA-bdg PF03444.15 KIR60586.1 - 0.017 14.8 0.0 0.069 12.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_24 PF13412.6 KIR60586.1 - 0.026 14.1 0.0 0.31 10.6 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KIR60586.1 - 0.029 14.4 1.2 0.1 12.7 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_IclR PF09339.10 KIR60586.1 - 0.083 12.7 0.0 0.083 12.7 0.0 4.3 4 2 0 4 4 4 0 IclR helix-turn-helix domain DUF1131 PF06572.12 KIR60586.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Fe_dep_repress PF01325.19 KIR60586.1 - 0.094 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RuvB_C PF05491.13 KIR60586.1 - 0.14 12.0 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain DnaJ_C PF01556.18 KIR60587.1 - 3.2e-38 131.1 0.0 4.1e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIR60587.1 - 1.4e-26 92.3 0.7 2.2e-26 91.7 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIR60587.1 - 2.2e-11 44.0 13.3 3.6e-11 43.3 13.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIR60587.1 - 0.00022 21.1 9.7 0.092 12.7 2.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 KIR60587.1 - 8.1 6.9 8.8 6.2 7.3 0.9 2.8 2 1 1 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.19 KIR60587.1 - 8.4 6.5 7.3 3.4e+02 1.3 7.3 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Methyltrans_RNA PF04452.14 KIR60588.1 - 3.8e-57 193.2 0.0 4.3e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase adh_short_C2 PF13561.6 KIR60589.1 - 7.5e-52 176.2 1.4 9.6e-52 175.9 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR60589.1 - 7.4e-50 169.1 0.0 9.2e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR60589.1 - 2.5e-08 34.0 0.1 5.7e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR60589.1 - 0.00016 21.3 0.1 0.0023 17.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIR60589.1 - 0.1 12.2 0.4 0.18 11.3 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family HTH_29 PF13551.6 KIR60589.1 - 0.21 11.6 1.9 0.38 10.8 0.6 2.1 2 0 0 2 2 2 0 Winged helix-turn helix NAD_binding_10 PF13460.6 KIR60589.1 - 0.48 10.3 3.9 0.78 9.6 3.9 1.6 1 1 0 1 1 1 0 NAD(P)H-binding HIT PF01230.23 KIR60590.1 - 4.6e-23 81.8 0.0 5.1e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIR60590.1 - 2.1e-17 63.6 0.0 2.4e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Beta-lactamase PF00144.24 KIR60591.1 - 4.1e-51 174.2 11.1 5.2e-51 173.9 11.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KIR60591.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase PhoH PF02562.16 KIR60592.1 - 1.8e-88 295.4 0.5 4.9e-50 169.8 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein LAGLIDADG_3 PF14528.6 KIR60592.1 - 4.2e-10 39.8 0.0 5.4e-07 29.8 0.0 3.0 3 0 0 3 3 3 2 LAGLIDADG-like domain AAA_30 PF13604.6 KIR60592.1 - 8.9e-08 32.1 0.4 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIR60592.1 - 3.5e-06 27.4 0.0 0.075 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIR60592.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KIR60592.1 - 0.0016 18.7 0.0 5 7.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain Zot PF05707.12 KIR60592.1 - 0.0044 16.7 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) Hint_2 PF13403.6 KIR60592.1 - 0.0099 16.2 0.2 0.2 12.0 0.0 2.6 2 0 0 2 2 2 1 Hint domain Hom_end PF05204.14 KIR60592.1 - 0.01 16.0 0.0 0.027 14.6 0.0 1.7 2 0 0 2 2 2 0 Homing endonuclease DEAD PF00270.29 KIR60592.1 - 0.053 13.3 0.5 0.41 10.4 0.2 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KIR60592.1 - 0.053 13.0 0.9 4 6.9 0.1 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Hom_end_hint PF05203.16 KIR60592.1 - 0.063 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint UPF0054 PF02130.17 KIR60593.1 - 2.5e-39 134.0 0.0 2.9e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Acyl_transf_3 PF01757.22 KIR60595.1 - 3.3e-21 75.7 32.9 4.3e-21 75.3 32.9 1.1 1 0 0 1 1 1 1 Acyltransferase family Prenyltransf PF01255.19 KIR60596.1 - 1.2e-71 240.8 0.0 1.4e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase 6PGD PF00393.19 KIR60598.1 - 2.8e-122 407.6 0.0 3.5e-122 407.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIR60598.1 - 6e-50 169.5 0.0 9.8e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIR60598.1 - 0.00018 22.0 0.0 0.00054 20.5 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIR60598.1 - 0.00029 20.9 0.0 0.00065 19.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIR60598.1 - 0.0018 18.0 0.0 0.004 16.8 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KIR60598.1 - 0.0037 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KIR60598.1 - 0.02 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 KIR60598.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_4 PF13439.6 KIR60598.1 - 0.06 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 CbiQ PF02361.16 KIR60599.1 - 3.3e-25 89.0 10.2 4.4e-25 88.6 10.2 1.1 1 0 0 1 1 1 1 Cobalt transport protein ABC_tran PF00005.27 KIR60600.1 - 7.3e-53 178.8 0.0 8.6e-27 94.3 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR60600.1 - 4.3e-17 62.9 0.1 6.7e-05 22.8 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR60600.1 - 1.4e-09 37.6 0.6 4.7e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KIR60600.1 - 8.7e-07 28.7 1.6 0.007 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIR60600.1 - 1.6e-06 28.8 0.0 0.006 17.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIR60600.1 - 3.4e-06 26.6 0.5 0.0068 15.8 0.0 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KIR60600.1 - 5.5e-06 26.4 0.2 0.0071 16.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KIR60600.1 - 5.8e-06 26.2 0.2 0.085 12.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 KIR60600.1 - 7.5e-06 26.4 8.2 0.0014 19.0 0.6 2.7 2 2 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KIR60600.1 - 1.7e-05 24.4 0.0 0.31 10.4 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR60600.1 - 0.0001 22.6 0.0 0.28 11.5 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KIR60600.1 - 0.00039 21.0 0.1 0.38 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIR60600.1 - 0.0005 20.4 0.2 0.12 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIR60600.1 - 0.0006 19.8 1.0 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KIR60600.1 - 0.00064 19.5 0.1 0.47 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIR60600.1 - 0.00067 19.7 0.0 0.093 12.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 KIR60600.1 - 0.0008 19.6 0.7 0.92 9.8 0.0 3.9 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KIR60600.1 - 0.001 19.2 2.0 0.45 10.7 0.1 3.0 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KIR60600.1 - 0.0011 19.0 1.4 0.1 12.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 KIR60600.1 - 0.0012 18.4 0.3 0.48 10.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIR60600.1 - 0.0029 18.0 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIR60600.1 - 0.0042 16.8 1.9 0.12 12.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIR60600.1 - 0.0042 17.4 0.0 0.66 10.4 0.0 2.2 2 0 0 2 2 2 1 RNA helicase CbiA PF01656.23 KIR60600.1 - 0.0049 16.9 0.2 0.31 11.1 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KIR60600.1 - 0.0094 15.5 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 KIR60600.1 - 0.014 15.5 0.4 5.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 KIR60600.1 - 0.025 14.5 0.1 1.8 8.5 0.0 3.0 4 0 0 4 4 3 0 NTPase Cytidylate_kin PF02224.18 KIR60600.1 - 0.026 14.3 0.7 5.6 6.6 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase SRP54 PF00448.22 KIR60600.1 - 0.031 13.9 0.3 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KIR60600.1 - 0.039 14.2 0.0 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KIR60600.1 - 0.054 13.4 0.0 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain Phage_base_V PF04717.12 KIR60600.1 - 0.061 13.3 0.3 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector APS_kinase PF01583.20 KIR60600.1 - 0.088 12.7 0.1 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase MeaB PF03308.16 KIR60600.1 - 0.088 11.8 1.2 1.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 KIR60600.1 - 0.092 11.8 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_PrkA PF08298.11 KIR60600.1 - 0.097 11.6 0.7 3 6.6 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_14 PF13173.6 KIR60600.1 - 0.1 12.6 0.0 9.3 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 KIR60600.1 - 0.11 11.3 0.2 0.76 8.5 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ATP_bind_1 PF03029.17 KIR60600.1 - 0.18 11.5 0.2 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KIR60600.1 - 0.21 11.3 0.1 1.5 8.5 0.0 2.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KIR60600.1 - 0.23 11.5 0.3 5.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KIR60600.1 - 0.28 10.8 1.6 1.6 8.3 0.1 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KIR60600.1 - 0.29 10.8 0.0 13 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KIR60600.1 - 0.35 10.1 2.0 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin ABC_cobalt PF09819.9 KIR60601.1 - 5.3e-41 139.6 14.5 5.3e-41 139.6 14.5 1.7 2 0 0 2 2 2 1 ABC-type cobalt transport system, permease component Trep_Strep PF09605.10 KIR60601.1 - 0.0071 16.4 7.9 0.0071 16.4 7.9 1.6 1 1 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1980 PF09323.10 KIR60602.1 - 0.00099 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) TctB PF07331.11 KIR60602.1 - 0.0062 16.8 0.6 0.012 15.9 0.6 1.4 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family SIS_2 PF13580.6 KIR60603.1 - 5.9e-40 136.5 1.0 1.1e-39 135.6 0.2 1.7 2 0 0 2 2 2 1 SIS domain SIS PF01380.22 KIR60603.1 - 0.0028 17.5 0.4 0.011 15.5 0.0 2.1 3 0 0 3 3 3 1 SIS domain DUF2529 PF10740.9 KIR60603.1 - 0.0063 16.2 0.1 1.3 8.7 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF2529) AA_permease PF00324.21 KIR60604.1 - 0.0012 17.5 2.9 0.0015 17.2 2.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2070 PF09843.9 KIR60604.1 - 0.091 11.0 4.1 0.11 10.7 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Acyl-CoA_dh_1 PF00441.24 KIR60605.1 - 1.7e-32 112.7 2.0 1.7e-32 112.7 2.0 2.8 4 0 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR60605.1 - 5.4e-23 81.0 0.0 1.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIR60605.1 - 7.1e-23 81.4 0.0 2.3e-22 79.8 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF1974 PF09317.11 KIR60605.1 - 2e-08 34.1 0.2 4.3e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_2 PF08028.11 KIR60605.1 - 2e-05 24.9 0.3 2e-05 24.9 0.3 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KIR60605.1 - 0.00022 21.0 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MlaE PF02405.16 KIR60605.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Permease MlaE FUR PF01475.19 KIR60606.1 - 1.4e-29 102.7 0.0 1.5e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_32 PF13565.6 KIR60606.1 - 0.06 14.0 0.6 0.37 11.4 0.1 2.1 2 1 0 2 2 2 0 Homeodomain-like domain HTH_5 PF01022.20 KIR60607.1 - 2e-16 59.5 0.1 3.8e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR60607.1 - 1.6e-10 40.9 1.7 1.6e-10 40.9 1.7 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR60607.1 - 0.028 14.3 0.7 0.043 13.7 0.7 1.4 1 1 0 1 1 1 0 MarR family Rrf2 PF02082.20 KIR60607.1 - 0.035 14.5 0.1 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 KIR60607.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KIR60607.1 - 0.092 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 KIR60607.1 - 0.13 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HxlR PF01638.17 KIR60607.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix ABC-3 PF00950.17 KIR60608.1 - 9.6e-63 212.1 29.3 1.1e-62 211.8 29.3 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 KIR60608.1 - 6e-05 22.2 31.7 6.3e-05 22.1 30.4 1.7 1 1 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 KIR60609.1 - 1e-29 103.8 0.0 1.3e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR60609.1 - 9.2e-08 32.2 0.1 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR60609.1 - 5.5e-05 22.8 0.1 0.0001 22.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR60609.1 - 0.00026 20.5 0.1 0.0067 15.9 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR60609.1 - 0.0015 19.0 0.0 0.0021 18.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR60609.1 - 0.0092 16.4 2.2 0.035 14.5 2.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KIR60609.1 - 0.015 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KIR60609.1 - 0.03 14.0 0.8 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIR60609.1 - 0.04 14.0 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR60609.1 - 0.059 13.3 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 KIR60609.1 - 0.067 13.4 0.3 1.1 9.5 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 KIR60609.1 - 0.075 12.9 0.0 0.4 10.6 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_27 PF13514.6 KIR60609.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIR60609.1 - 0.085 13.1 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR60609.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KIR60609.1 - 0.13 12.5 0.4 0.27 11.5 0.2 1.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIR60609.1 - 0.15 11.4 0.2 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KIR60609.1 - 0.16 12.1 0.2 0.37 11.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIR60609.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KIR60609.1 - 0.23 11.1 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.6 KIR60609.1 - 0.26 11.0 0.0 0.34 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KIR60609.1 - 0.31 10.2 0.1 0.53 9.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_ATPase PF09818.9 KIR60609.1 - 0.33 9.7 0.2 1.1 8.0 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ZnuA PF01297.17 KIR60610.1 - 4e-73 246.0 0.0 4.6e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic ACC_epsilon PF13822.6 KIR60611.1 - 2.3 9.0 8.8 0.26 12.0 1.1 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit ABM PF03992.16 KIR60612.1 - 1.1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase HGTP_anticodon PF03129.20 KIR60613.1 - 1.1e-23 83.2 0.1 2.4e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIR60613.1 - 3.6e-08 33.6 0.0 7.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HypA PF01155.19 KIR60613.1 - 0.047 13.7 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 KIR60613.1 - 0.082 12.9 0.6 0.3 11.1 0.7 1.9 1 1 0 1 1 1 0 CpXC protein zinc_ribbon_4 PF13717.6 KIR60613.1 - 0.094 12.7 0.5 8.4 6.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF530 PF04409.12 KIR60613.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Cytochrome_C7 PF14522.6 KIR60613.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF2752 PF10825.8 KIR60613.1 - 0.19 11.8 1.2 3.1 7.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Peptidase_C39_2 PF13529.6 KIR60614.1 - 1.8e-21 77.2 0.1 2.7e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family ssDNA_TraI_N PF18272.1 KIR60614.1 - 0.014 15.4 0.1 0.044 13.8 0.1 1.8 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain BtrH_N PF14399.6 KIR60614.1 - 0.042 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Glyco_hydro_20 PF00728.22 KIR60615.1 - 1.1e-79 268.4 0.0 5.1e-77 259.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KIR60615.1 - 2.4e-23 83.3 0.0 5.9e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 KIR60615.1 - 5.8e-05 23.8 0.0 9.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like PEP-utilizers_C PF02896.18 KIR60616.1 - 2.9e-81 272.8 0.0 4.1e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 KIR60616.1 - 2.1e-57 194.9 0.0 3.9e-31 108.5 0.0 4.2 2 1 2 4 4 4 4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KIR60616.1 - 1.9e-25 88.4 1.7 5.8e-25 86.8 1.7 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Robl_LC7 PF03259.17 KIR60617.1 - 7.3e-16 57.7 0.1 1.2e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Glyoxalase_6 PF18029.1 KIR60618.1 - 2.3e-28 99.1 1.3 2.5e-28 99.0 1.3 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KIR60618.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HD_assoc PF13286.6 KIR60619.1 - 1.3e-22 80.1 0.1 3.1e-22 78.9 0.0 1.7 2 0 0 2 2 2 1 Phosphohydrolase-associated domain HD PF01966.22 KIR60619.1 - 4.2e-19 68.9 0.0 1e-18 67.7 0.0 1.6 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 KIR60619.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Nudix_N PF12535.8 KIR60619.1 - 0.017 14.7 0.1 0.2 11.3 0.1 2.5 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal SIP PF04954.13 KIR60620.1 - 2.1e-41 141.2 0.5 3.6e-41 140.4 0.5 1.4 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 KIR60620.1 - 1.9e-31 108.8 0.0 3.8e-31 107.8 0.0 1.5 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain FAD_binding_6 PF00970.24 KIR60620.1 - 0.14 12.5 0.0 0.67 10.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Toprim_N PF08275.11 KIR60621.1 - 1.4e-38 131.8 0.0 2e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 KIR60621.1 - 1.4e-32 111.4 0.0 2.9e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 KIR60621.1 - 3.3e-25 89.1 0.1 7.1e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 DNA primase DnaG DnaB-binding Toprim_4 PF13662.6 KIR60621.1 - 4.7e-17 62.2 0.1 1.2e-16 60.9 0.1 1.7 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 KIR60621.1 - 1.6e-15 57.0 0.5 6.5e-15 55.1 0.3 2.3 2 0 0 2 2 2 1 DnaB-helicase binding domain of primase Toprim_2 PF13155.6 KIR60621.1 - 8.4e-09 35.7 0.0 2.7e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 KIR60621.1 - 2.4e-07 30.9 0.1 7e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 KIR60621.1 - 0.012 15.9 1.4 0.038 14.3 0.1 2.5 3 0 0 3 3 3 0 Toprim domain Serglycin PF04360.12 KIR60622.1 - 0.023 14.7 2.0 0.035 14.0 2.0 1.2 1 0 0 1 1 1 0 Serglycin ROK PF00480.20 KIR60623.1 - 6.8e-54 183.3 0.1 8e-54 183.1 0.1 1.0 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 KIR60623.1 - 0.0004 19.9 0.1 0.00079 18.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR60623.1 - 0.0014 18.5 2.8 0.0014 18.5 2.8 2.1 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 KIR60623.1 - 0.0063 16.6 2.3 0.0063 16.6 2.3 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR60623.1 - 5.9 6.8 7.9 2.2 8.1 3.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain ABC_tran PF00005.27 KIR60624.1 - 8.2e-47 159.2 0.0 7e-25 88.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR60624.1 - 1.9e-09 37.8 0.0 0.0038 17.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR60624.1 - 3.3e-05 23.5 0.1 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR60624.1 - 0.0001 21.8 0.2 1.4 8.3 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIR60624.1 - 0.00013 21.9 0.2 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KIR60624.1 - 0.0016 18.2 5.6 0.0024 17.6 0.0 2.8 2 2 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIR60624.1 - 0.01 15.9 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KIR60624.1 - 0.021 15.3 0.0 0.05 14.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KIR60624.1 - 0.029 13.2 0.3 11 4.6 0.0 3.5 4 1 0 4 4 4 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 KIR60624.1 - 0.033 13.8 2.0 0.57 9.7 0.3 3.0 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIR60624.1 - 0.034 13.4 0.5 0.47 9.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 KIR60624.1 - 0.042 14.2 1.0 0.91 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KIR60624.1 - 0.13 12.5 0.0 45 4.4 0.0 3.1 2 1 1 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KIR60624.1 - 0.15 12.5 0.2 2.2 8.7 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIR60624.1 - 0.21 11.8 1.0 3.8 7.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain BPD_transp_2 PF02653.16 KIR60625.1 - 4.5e-45 153.9 45.4 4.5e-45 153.9 45.4 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF543 PF04418.12 KIR60625.1 - 0.25 11.3 3.4 1.7 8.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Peripla_BP_4 PF13407.6 KIR60626.1 - 6.1e-35 121.0 9.4 8.2e-35 120.6 9.4 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KIR60626.1 - 1.4e-12 47.6 0.8 1.8e-12 47.3 0.8 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 KIR60626.1 - 5.7e-06 26.8 0.1 5.9e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain TAT_signal PF10518.9 KIR60626.1 - 8.2e-05 22.3 4.6 8.2e-05 22.3 4.6 2.7 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence GFO_IDH_MocA PF01408.22 KIR60627.1 - 5.6e-23 82.0 0.2 1e-22 81.2 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR60627.1 - 7.3e-12 45.3 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KIR60627.1 - 1.2e-05 25.9 0.4 3e-05 24.7 0.4 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_5 PF07994.12 KIR60628.1 - 7.7e-44 150.4 0.0 3.7e-41 141.6 0.0 2.9 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KIR60628.1 - 1.1e-23 83.6 0.0 1.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase TIP39 PF14980.6 KIR60628.1 - 0.23 11.3 4.7 0.24 11.3 0.6 2.4 2 0 0 2 2 2 0 TIP39 peptide UbiA PF01040.18 KIR60629.1 - 1.7e-14 53.8 21.9 1.7e-14 53.8 21.9 2.3 1 1 1 2 2 2 1 UbiA prenyltransferase family Peptidase_C26 PF07722.13 KIR60629.1 - 0.039 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 AP_endonuc_2 PF01261.24 KIR60631.1 - 7.7e-10 38.6 0.5 3.8e-09 36.3 0.4 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyoxalase_4 PF13669.6 KIR60631.1 - 0.14 12.5 2.2 2.8 8.3 0.0 2.9 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Phosphodiest PF01663.22 KIR60632.1 - 1.3e-55 189.4 0.0 1.5e-55 189.2 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase polyprenyl_synt PF00348.17 KIR60633.1 - 1.8e-47 161.6 0.0 2.5e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ThuA PF06283.11 KIR60634.1 - 4.2e-80 268.9 2.9 5.8e-80 268.4 2.9 1.2 1 0 0 1 1 1 1 Trehalose utilisation DUF1080 PF06439.11 KIR60634.1 - 3.4e-38 131.6 0.5 7.6e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1080) Ricin_B_lectin PF00652.22 KIR60634.1 - 8.6e-32 110.1 8.0 8.6e-32 110.1 8.0 1.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR60634.1 - 5.1e-27 94.4 15.9 2.4e-13 50.6 1.2 4.6 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like ET PF01684.16 KIR60634.1 - 0.54 10.6 3.4 41 4.6 0.1 3.2 1 1 1 3 3 3 0 ET module AP_endonuc_2 PF01261.24 KIR60635.1 - 4.1e-39 134.2 0.7 5.1e-39 133.9 0.7 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 KIR60635.1 - 4.9e-24 83.8 0.1 1.6e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus ROK PF00480.20 KIR60636.1 - 2e-47 162.1 0.0 2.4e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR60636.1 - 0.00011 22.1 4.1 0.00011 22.1 4.1 2.6 2 0 0 2 2 2 1 MarR family HTH_AsnC-type PF13404.6 KIR60636.1 - 0.0026 17.5 2.2 0.0026 17.5 2.2 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.22 KIR60636.1 - 0.053 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.6 KIR60636.1 - 0.074 13.6 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_20 PF12840.7 KIR60636.1 - 0.09 12.8 4.3 0.083 13.0 1.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR60636.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TCR PF03638.15 KIR60636.1 - 0.43 10.9 1.9 0.66 10.3 1.9 1.2 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain AP_endonuc_2 PF01261.24 KIR60637.1 - 9.9e-29 100.3 0.0 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TAT_signal PF10518.9 KIR60637.1 - 0.74 9.8 6.8 1.6 8.7 6.8 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence MMPL PF03176.15 KIR60639.1 - 8.6e-123 409.5 29.0 1.9e-69 234.1 9.1 2.1 2 0 0 2 2 2 2 MMPL family Amino_oxidase PF01593.24 KIR60640.1 - 3.9e-37 128.6 0.4 4.9e-37 128.3 0.4 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR60640.1 - 9.4e-16 57.8 0.8 2.5e-15 56.5 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR60640.1 - 3.2e-06 26.5 1.9 5.2e-06 25.8 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIR60640.1 - 3.7e-06 26.6 2.9 5e-06 26.1 2.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIR60640.1 - 6.7e-06 25.6 0.6 1.1e-05 24.8 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR60640.1 - 3.2e-05 23.3 0.2 5.9e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIR60640.1 - 0.00016 20.9 0.8 0.00028 20.1 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KIR60640.1 - 0.00016 20.9 0.1 0.00023 20.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KIR60640.1 - 0.00022 20.9 9.0 0.0013 18.4 9.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR60640.1 - 0.00097 17.9 0.1 0.0016 17.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KIR60640.1 - 0.0014 19.2 0.2 0.0024 18.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIR60640.1 - 0.0018 17.5 0.1 0.0034 16.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIR60640.1 - 0.051 12.8 0.3 0.092 12.0 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIR60640.1 - 0.13 11.5 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PIN PF01850.21 KIR60641.1 - 2.4e-10 41.0 0.7 2.9e-10 40.7 0.7 1.1 1 0 0 1 1 1 1 PIN domain PhdYeFM_antitox PF02604.19 KIR60642.1 - 5.1e-10 39.0 0.0 7.1e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system FecCD PF01032.18 KIR60644.1 - 2.3e-66 224.0 42.3 2.8e-66 223.7 42.3 1.1 1 0 0 1 1 1 1 FecCD transport family Peripla_BP_2 PF01497.18 KIR60645.1 - 1.7e-21 76.8 0.1 2.2e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Ribosomal_L11 PF00298.19 KIR60645.1 - 0.032 14.7 0.1 0.079 13.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain FAD_binding_9 PF08021.11 KIR60646.1 - 1.2e-31 109.5 0.0 2e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 KIR60646.1 - 4.8e-20 72.3 0.6 8.6e-20 71.4 0.6 1.4 1 0 0 1 1 1 1 Siderophore-interacting protein Epimerase PF01370.21 KIR60647.1 - 8.7e-12 45.0 1.7 5.9e-11 42.3 1.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR60647.1 - 2.4e-10 40.6 5.0 4.8e-10 39.6 5.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR60647.1 - 3.8e-07 29.9 3.8 5.5e-07 29.4 3.8 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KIR60647.1 - 7.2e-06 25.3 0.2 1.1e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIR60647.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR60647.1 - 2.4e-05 23.5 0.1 3.3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIR60647.1 - 3.3e-05 23.2 0.0 5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KIR60647.1 - 0.0041 16.6 0.8 0.0062 16.0 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.15 KIR60647.1 - 0.046 13.9 0.2 0.089 13.0 0.1 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KIR60647.1 - 0.052 13.8 0.5 0.11 12.8 0.5 1.6 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 KIR60647.1 - 0.059 13.5 0.7 0.13 12.4 0.7 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KIR60647.1 - 0.078 12.9 2.5 0.28 11.1 2.5 1.8 1 1 0 1 1 1 0 KR domain Methyltransf_11 PF08241.12 KIR60647.1 - 0.14 12.8 0.4 0.25 12.0 0.4 1.4 1 0 0 1 1 1 0 Methyltransferase domain ApbA PF02558.16 KIR60647.1 - 0.17 11.5 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amidohydro_2 PF04909.14 KIR60648.1 - 4.4e-27 95.6 3.8 5e-27 95.4 3.8 1.0 1 0 0 1 1 1 1 Amidohydrolase Glyoxalase PF00903.25 KIR60649.1 - 9.4e-07 29.1 0.1 7.4e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR60649.1 - 2.8e-05 24.9 0.1 3.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KIR60649.1 - 0.0089 15.9 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIR60649.1 - 0.034 14.4 0.1 0.68 10.2 0.1 2.1 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rad21_Rec8 PF04824.16 KIR60649.1 - 0.065 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein NMT1 PF09084.11 KIR60650.1 - 1.7e-66 224.3 0.5 2.2e-66 223.9 0.1 1.4 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 KIR60650.1 - 0.00085 19.1 0.0 0.0054 16.5 0.0 2.2 3 0 0 3 3 3 1 NMT1-like family BPD_transp_1 PF00528.22 KIR60651.1 - 1.3e-21 77.1 16.8 1.3e-21 77.1 16.8 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Bac_luciferase PF00296.20 KIR60652.1 - 1.1e-53 182.7 13.8 1.9e-53 181.9 13.8 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Response_reg PF00072.24 KIR60654.1 - 2.8e-23 82.2 0.0 3.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR60654.1 - 6e-19 67.3 0.0 8.6e-19 66.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR60654.1 - 0.0002 21.0 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR60654.1 - 0.00054 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF742 PF05331.11 KIR60654.1 - 0.00065 19.5 0.6 0.0019 18.0 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF742) Sigma70_r4 PF04545.16 KIR60654.1 - 0.00086 18.8 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR60654.1 - 0.005 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KIR60654.1 - 0.026 14.6 0.0 0.084 13.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 KIR60654.1 - 0.12 12.4 1.3 1.7 8.8 0.1 2.9 2 2 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 KIR60654.1 - 0.2 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 KIR60655.1 - 7.5e-30 104.2 0.0 9.6e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR60655.1 - 6.7e-09 36.0 0.0 0.0012 18.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR60655.1 - 3.1e-05 23.6 0.1 5.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR60655.1 - 7e-05 23.1 0.0 0.00033 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIR60655.1 - 0.00024 20.6 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR60655.1 - 0.00046 20.8 0.0 0.0006 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR60655.1 - 0.00083 19.8 0.4 0.0013 19.2 0.4 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KIR60655.1 - 0.0012 18.4 0.3 0.023 14.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIR60655.1 - 0.0019 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KIR60655.1 - 0.0025 17.6 1.3 0.012 15.4 0.5 2.2 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 KIR60655.1 - 0.04 13.3 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_10 PF12846.7 KIR60655.1 - 0.13 11.2 0.0 1.6 7.6 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 KIR60655.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KIR60655.1 - 0.21 11.3 0.1 0.45 10.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain Acyl-CoA_dh_2 PF08028.11 KIR60656.1 - 1.7e-25 89.9 8.8 1.7e-25 89.9 8.8 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR60656.1 - 4.5e-08 33.8 0.0 1.1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIR60656.1 - 6.1e-08 33.0 1.9 6.6e-08 32.9 0.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR60656.1 - 0.004 17.3 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Response_reg PF00072.24 KIR60657.1 - 1.8e-21 76.4 0.0 2.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR60657.1 - 3.7e-19 68.0 0.0 5.3e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR60657.1 - 1.4e-06 27.8 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KIR60657.1 - 0.00036 20.2 0.1 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR60657.1 - 0.00076 18.9 0.2 0.0019 17.7 0.2 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 TadZ_N PF16968.5 KIR60657.1 - 0.002 17.8 2.7 0.002 17.8 2.7 1.5 2 0 0 2 2 2 1 Pilus assembly protein TadZ N-terminal HTH_23 PF13384.6 KIR60657.1 - 0.0059 16.4 0.3 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.7 KIR60657.1 - 0.0066 16.5 0.3 0.023 14.8 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR60657.1 - 0.014 15.4 0.1 0.043 13.8 0.1 2.0 1 0 0 1 1 1 0 Winged helix-turn helix HTH_40 PF14493.6 KIR60657.1 - 0.021 15.3 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR60657.1 - 0.025 14.1 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KIR60657.1 - 0.06 13.2 0.1 2.9 7.8 0.0 2.5 1 1 1 2 2 2 0 HTH DNA binding domain Bac_luciferase PF00296.20 KIR60658.1 - 2.2e-56 191.6 5.1 1.4e-53 182.4 2.4 2.0 1 1 1 2 2 2 2 Luciferase-like monooxygenase Hydrolase_4 PF12146.8 KIR60659.1 - 8.9e-06 25.1 0.0 2.3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 KIR60659.1 - 0.0018 17.7 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Palm_thioest PF02089.15 KIR60659.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MlaC PF05494.12 KIR60660.1 - 0.0076 16.0 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 MlaC protein DUF4878 PF12870.7 KIR60660.1 - 0.08 13.2 0.0 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4878) TSP_3 PF02412.18 KIR60661.1 - 0.0081 15.8 3.6 0.0081 15.8 3.6 2.3 2 0 0 2 2 2 1 Thrombospondin type 3 repeat CagY_I PF14585.6 KIR60661.1 - 0.017 15.2 0.4 0.031 14.4 0.4 1.4 1 1 0 1 1 1 0 CagY type 1 repeat FG-GAP PF01839.23 KIR60661.1 - 0.046 13.9 15.5 0.051 13.7 1.8 2.8 3 0 0 3 3 3 0 FG-GAP repeat VCBS PF13517.6 KIR60661.1 - 0.046 14.3 14.6 1.3 9.7 1.4 3.3 1 1 3 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 KIR60661.1 - 0.11 12.0 9.3 2.2 7.9 0.3 3.2 3 0 0 3 3 3 0 EF hand DEC-1_N PF04625.13 KIR60661.1 - 4.4 6.2 12.8 5.2 6.0 12.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region EF-hand_1 PF00036.32 KIR60661.1 - 5.4 6.8 8.4 24 4.8 0.2 3.1 3 0 0 3 3 3 0 EF hand CBS PF00571.28 KIR60662.1 - 1.7e-14 54.0 0.5 3.4e-07 30.6 0.0 2.8 3 0 0 3 3 3 2 CBS domain Peptidase_M50 PF02163.22 KIR60662.1 - 9.5e-12 44.7 8.6 2.1e-08 33.8 0.3 2.5 1 1 1 2 2 2 2 Peptidase family M50 SH3_3 PF08239.11 KIR60664.1 - 0.023 14.9 0.1 0.036 14.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain DUF397 PF04149.12 KIR60665.1 - 4.1e-23 81.2 0.3 4.6e-23 81.0 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) YkuD PF03734.14 KIR60666.1 - 5.4e-12 46.4 0.0 1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Alpha-amylase PF00128.24 KIR60667.1 - 5.4e-18 65.6 0.0 1.5e-17 64.2 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIR60667.1 - 2.4e-12 47.2 0.1 5.4e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain EAL PF00563.20 KIR60667.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 EAL domain Complex1_51K PF01512.17 KIR60669.1 - 4.3e-29 101.3 0.0 1.3e-28 99.8 0.0 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KIR60669.1 - 9.2e-15 54.5 0.0 2.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Fer4_15 PF13459.6 KIR60669.1 - 8.8e-11 42.4 0.0 2.5e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain SLBB PF10531.9 KIR60669.1 - 0.00063 19.6 0.0 0.0025 17.6 0.1 2.1 2 0 0 2 2 2 1 SLBB domain Fer4_13 PF13370.6 KIR60669.1 - 0.002 18.6 0.0 0.0056 17.2 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I tRNA-synt_2b PF00587.25 KIR60670.1 - 7.7e-27 94.4 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIR60670.1 - 1.3e-14 54.3 6.9 1.9e-14 53.8 6.9 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KIR60670.1 - 0.037 13.4 5.5 0.055 12.8 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ING PF12998.7 KIR60670.1 - 0.08 13.5 0.9 0.15 12.6 0.9 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YlqD PF11068.8 KIR60670.1 - 0.17 12.3 0.5 0.32 11.3 0.5 1.4 1 0 0 1 1 1 0 YlqD protein Spectrin PF00435.21 KIR60670.1 - 0.24 11.9 4.0 0.46 11.0 4.0 1.5 1 0 0 1 1 1 0 Spectrin repeat DUF3813 PF12758.7 KIR60670.1 - 0.31 11.4 3.6 0.89 9.9 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Suppressor_APC PF11414.8 KIR60670.1 - 1.6 8.9 4.4 8.8 6.5 4.4 2.1 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein FlgN PF05130.12 KIR60670.1 - 2.1 8.9 6.1 4.1 7.9 6.1 1.5 1 0 0 1 1 1 0 FlgN protein DinB_2 PF12867.7 KIR60670.1 - 4.9 7.7 7.7 17 5.9 5.7 2.7 2 1 0 2 2 2 0 DinB superfamily Sacchrp_dh_NADP PF03435.18 KIR60671.1 - 4.4e-13 49.6 0.0 7.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIR60671.1 - 9.5e-06 25.6 0.4 2e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KIR60671.1 - 0.0097 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KIR60671.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Lambda_tail_I PF06805.12 KIR60671.1 - 0.15 12.4 1.1 1.7 9.0 0.1 2.8 2 1 1 3 3 3 0 Bacteriophage lambda tail assembly protein I STAS_2 PF13466.6 KIR60673.1 - 6.5e-10 39.2 0.0 9.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KIR60673.1 - 1.5e-08 34.3 0.0 1.8e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 STAS domain Polyketide_cyc2 PF10604.9 KIR60674.1 - 0.0018 18.5 0.2 0.0022 18.3 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HOOK PF05622.12 KIR60675.1 - 0.47 8.6 3.6 2.7 6.1 1.3 2.0 2 0 0 2 2 2 0 HOOK protein AAA_19 PF13245.6 KIR60676.1 - 5e-14 52.9 0.0 2.1e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIR60676.1 - 3.5e-11 43.2 0.0 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIR60676.1 - 3e-08 33.4 0.1 9.8e-08 31.7 0.1 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KIR60676.1 - 5.5e-07 29.2 0.0 0.0075 15.7 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 KIR60676.1 - 1.9e-06 27.8 1.0 0.021 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KIR60676.1 - 3.9e-06 26.9 0.0 8.9e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KIR60676.1 - 8e-06 25.8 0.0 0.00049 19.9 0.0 2.8 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KIR60676.1 - 0.0021 17.4 0.8 0.011 15.0 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 KIR60676.1 - 0.0068 15.8 0.0 0.089 12.1 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 KIR60676.1 - 0.0093 15.8 0.0 0.053 13.3 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KIR60676.1 - 0.016 14.8 0.7 0.11 12.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KIR60676.1 - 0.026 14.9 1.9 0.05 14.0 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 KIR60676.1 - 0.062 13.6 0.3 12 6.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIR60676.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Abhydrolase_6 PF12697.7 KIR60677.1 - 2.9e-27 96.7 16.8 3.5e-27 96.4 16.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR60677.1 - 1.7e-21 76.6 1.4 1.1e-20 73.9 1.4 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR60677.1 - 1.8e-16 60.6 0.1 4e-13 49.6 0.4 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 KIR60677.1 - 1.2e-07 32.1 0.1 3.4e-07 30.6 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 KIR60677.1 - 0.00025 20.8 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 KIR60677.1 - 0.00082 19.3 0.1 0.032 14.1 0.1 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 KIR60677.1 - 0.001 19.2 1.5 0.67 10.1 0.0 3.1 4 0 0 4 4 4 2 TAP-like protein Peptidase_S9 PF00326.21 KIR60677.1 - 0.014 14.9 0.9 0.26 10.7 0.5 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KIR60677.1 - 0.034 13.9 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ndr PF03096.14 KIR60677.1 - 0.06 12.0 0.0 0.094 11.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Palm_thioest PF02089.15 KIR60677.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DLH PF01738.18 KIR60677.1 - 0.11 12.0 0.0 6.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 KIR60677.1 - 0.11 12.2 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 KIR60677.1 - 0.11 11.8 0.0 0.25 10.7 0.1 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 KIR60677.1 - 0.18 10.9 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3145 PF11343.8 KIR60679.1 - 1.5e-68 229.3 0.1 1.6e-68 229.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) Glyco_hydro_3 PF00933.21 KIR60680.1 - 1.6e-83 280.8 0.2 2.6e-83 280.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIR60680.1 - 0.0027 17.7 0.5 0.021 14.8 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Rv2175c_C PF18367.1 KIR60680.1 - 0.12 12.4 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Glycos_transf_2 PF00535.26 KIR60681.1 - 9.5e-35 119.9 0.0 1.3e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR60681.1 - 3.6e-11 43.4 0.0 5.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIR60681.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KIR60681.1 - 0.0004 20.8 0.0 0.00085 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Amidohydro_2 PF04909.14 KIR60681.1 - 0.00094 19.0 0.4 0.0013 18.6 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase CBM9_1 PF06452.11 KIR60683.1 - 1.4e-22 80.5 0.0 2.3e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like PIG-L PF02585.17 KIR60683.1 - 2.5e-22 79.9 0.0 5.6e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase NPCBM_assoc PF10633.9 KIR60683.1 - 2.4e-12 46.9 20.3 7.8e-09 35.7 2.3 4.9 4 2 1 5 5 5 3 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.8 KIR60683.1 - 0.0013 18.9 0.8 4.9 7.4 0.0 4.3 4 1 1 5 5 5 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fn3-like PF14310.6 KIR60683.1 - 0.0061 16.6 0.5 14 5.9 0.0 4.3 4 0 0 4 4 4 1 Fibronectin type III-like domain DUF11 PF01345.18 KIR60683.1 - 0.027 14.7 14.3 0.74 10.2 0.6 4.7 3 2 0 3 3 3 0 Domain of unknown function DUF11 LpxK PF02606.14 KIR60683.1 - 0.097 11.7 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase MG2 PF01835.19 KIR60683.1 - 0.098 13.1 0.1 1.3 9.6 0.0 2.9 3 0 0 3 3 3 0 MG2 domain fn3_5 PF06280.12 KIR60683.1 - 0.12 13.1 1.4 45 4.8 0.1 4.2 3 2 1 5 5 5 0 Fn3-like domain ROK PF00480.20 KIR60684.1 - 1e-27 97.4 0.0 1.3e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR60684.1 - 0.0019 18.0 2.0 0.0036 17.2 0.3 2.4 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 KIR60684.1 - 0.0068 16.2 0.6 0.026 14.3 0.6 2.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR60684.1 - 0.014 14.9 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR60684.1 - 0.082 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_32 PF13565.6 KIR60684.1 - 0.18 12.5 2.8 0.89 10.2 0.1 3.0 3 1 0 3 3 3 0 Homeodomain-like domain SBP_bac_6 PF13343.6 KIR60685.1 - 2.1e-28 99.4 6.0 2.1e-28 99.4 6.0 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR60685.1 - 2.6e-14 53.7 8.3 3.8e-14 53.2 8.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR60685.1 - 8.9e-14 51.8 2.7 2.4e-13 50.4 2.7 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein ABC_tran PF00005.27 KIR60686.1 - 2e-32 112.6 0.0 4e-32 111.6 0.0 1.5 2 0 0 2 2 2 1 ABC transporter TOBE_2 PF08402.10 KIR60686.1 - 3.1e-14 52.9 3.7 3.2e-13 49.7 0.8 2.9 1 1 1 2 2 2 1 TOBE domain AAA_21 PF13304.6 KIR60686.1 - 1.7e-06 28.1 0.0 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE PF03459.17 KIR60686.1 - 0.014 15.7 3.5 0.064 13.6 0.5 2.6 2 0 0 2 2 2 0 TOBE domain AAA_22 PF13401.6 KIR60686.1 - 0.023 15.0 0.1 0.078 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIR60686.1 - 0.026 14.9 0.5 0.05 14.0 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 KIR60686.1 - 0.027 14.4 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KIR60686.1 - 0.03 14.7 0.2 0.083 13.3 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CysA_C_terminal PF17850.1 KIR60686.1 - 0.036 14.6 0.7 0.036 14.6 0.7 3.2 5 0 0 5 5 5 0 CysA C-terminal regulatory domain Rop PF01815.16 KIR60686.1 - 0.086 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Rop protein SbcCD_C PF13558.6 KIR60686.1 - 0.095 12.9 0.1 1.4 9.2 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Amidohydro_2 PF04909.14 KIR60687.1 - 2.2e-37 129.4 9.7 2.7e-37 129.1 9.7 1.1 1 0 0 1 1 1 1 Amidohydrolase Lyase_1 PF00206.20 KIR60688.1 - 5.1e-32 111.5 0.0 7.7e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KIR60688.1 - 2.7e-09 37.6 1.7 2.7e-09 37.6 1.7 2.6 3 0 0 3 3 3 1 Argininosuccinate lyase C-terminal CobT PF06213.12 KIR60688.1 - 0.42 10.0 5.7 0.83 9.0 5.7 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Methyltransf_23 PF13489.6 KIR60690.1 - 5.2e-15 55.7 0.0 7.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR60690.1 - 6.6e-15 55.5 0.1 1.8e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR60690.1 - 5.8e-10 39.7 0.0 1.2e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR60690.1 - 2e-05 25.3 0.0 4.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR60690.1 - 0.02 14.7 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HTH_31 PF13560.6 KIR60692.1 - 1.4e-12 47.8 1.6 1.4e-12 47.8 1.6 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR60692.1 - 6.5e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR60692.1 - 8e-09 35.4 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR60692.1 - 0.0088 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DUF397 PF04149.12 KIR60693.1 - 3.7e-19 68.5 0.4 4.1e-19 68.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) ketoacyl-synt PF00109.26 KIR60694.1 - 4.1e-54 183.8 5.0 4.1e-54 183.8 5.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIR60694.1 - 6.2e-32 110.1 1.4 1.3e-31 109.0 1.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KIR60694.1 - 1.1e-07 31.5 1.7 1.8e-07 30.8 0.3 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KIR60694.1 - 0.05 13.5 1.4 5.7 6.9 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.25 KIR60695.1 - 1.9e-14 53.8 0.1 2.1e-14 53.6 0.1 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KIR60695.1 - 0.00087 19.5 0.3 0.00097 19.3 0.3 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 KIR60695.1 - 0.0055 16.8 0.0 0.0058 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S DEK_C PF08766.11 KIR60695.1 - 0.012 15.5 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 DEK C terminal domain ACP_syn_III_C PF08541.10 KIR60696.1 - 1.2e-30 105.5 0.0 3.8e-29 100.7 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KIR60696.1 - 1.1e-27 95.7 0.7 4.5e-27 93.7 0.7 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KIR60696.1 - 1.8e-08 34.1 2.0 2.6e-08 33.6 0.7 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 KIR60696.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein ketoacyl-synt PF00109.26 KIR60696.1 - 0.046 13.3 7.4 0.083 12.4 5.4 2.3 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Chal_sti_synt_N PF00195.19 KIR60696.1 - 0.05 13.0 3.5 0.55 9.6 3.2 2.5 1 1 1 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Acyl_transf_1 PF00698.21 KIR60697.1 - 2.1e-15 57.0 0.2 3.1e-15 56.5 0.2 1.2 1 0 0 1 1 1 1 Acyl transferase domain Biotin_lipoyl PF00364.22 KIR60697.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme HTH_30 PF13556.6 KIR60698.1 - 4.2e-22 77.7 1.2 7.2e-22 77.0 0.2 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 KIR60698.1 - 3.9e-12 46.5 1.4 3.9e-12 46.5 1.4 3.2 3 1 0 3 3 3 1 GGDEF-like domain HTH_23 PF13384.6 KIR60698.1 - 0.02 14.7 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_8 PF02954.19 KIR60698.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 KIR60698.1 - 0.041 14.0 0.1 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HisKA_3 PF07730.13 KIR60699.1 - 6.2e-14 52.3 2.4 6.2e-14 52.3 2.4 3.1 3 0 0 3 3 3 1 Histidine kinase DUF872 PF05915.12 KIR60699.1 - 0.19 11.9 0.5 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) YesK PF14150.6 KIR60699.1 - 5.4 7.3 6.3 3.7 7.8 1.4 2.3 2 0 0 2 2 2 0 YesK-like protein DUF2417 PF10329.9 KIR60700.1 - 0.13 11.7 0.3 0.19 11.1 0.0 1.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) TctB PF07331.11 KIR60700.1 - 3.6 7.9 12.2 7.8 6.8 12.2 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family tRNA-synt_1c PF00749.21 KIR60703.1 - 8.2e-66 222.0 0.0 1.4e-65 221.2 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MFS_1 PF07690.16 KIR60704.1 - 9.6e-30 103.7 47.5 3.7e-20 72.1 15.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIR60704.1 - 5.4e-12 45.0 17.7 5.4e-12 45.0 17.7 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 KIR60704.1 - 5.4e-07 28.8 3.3 5.4e-07 28.8 3.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIR60704.1 - 0.0021 17.0 1.4 0.038 12.9 1.3 2.3 2 0 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 KIR60704.1 - 0.0026 16.3 2.7 0.0026 16.3 2.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 KIR60704.1 - 0.033 13.0 1.0 0.38 9.5 0.6 2.2 2 0 0 2 2 2 0 LacY proton/sugar symporter ATG22 PF11700.8 KIR60704.1 - 0.19 10.3 5.3 0.069 11.8 1.9 2.0 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Polyketide_cyc2 PF10604.9 KIR60705.1 - 1.4e-12 48.1 2.7 1.6e-12 47.9 2.7 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIR60705.1 - 1.6e-06 28.4 0.0 1.9e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 KIR60705.1 - 1.5e-05 25.2 0.2 2.9e-05 24.3 0.2 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 KIR60705.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.6 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) PDH_E1_M PF17831.1 KIR60706.1 - 4.9e-113 376.4 0.1 6.9e-113 375.8 0.1 1.2 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 KIR60706.1 - 1.6e-13 50.3 0.0 3.6e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KIR60706.1 - 0.013 15.3 0.0 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain PhoD PF09423.10 KIR60707.1 - 8.1e-111 370.4 2.4 1e-110 370.1 2.4 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KIR60707.1 - 1.3e-32 112.2 0.0 2.4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KIR60707.1 - 0.00034 21.1 0.0 0.00077 20.0 0.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain TAT_signal PF10518.9 KIR60707.1 - 0.0027 17.5 6.3 0.0027 17.5 6.3 2.6 1 1 1 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence MarR_2 PF12802.7 KIR60708.1 - 3.2e-15 55.7 1.7 3.2e-15 55.7 1.7 2.4 3 0 0 3 3 3 1 MarR family MarR PF01047.22 KIR60708.1 - 3.7e-14 52.4 0.1 8.3e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR60708.1 - 4.5e-12 46.3 1.2 6.6e-12 45.7 0.2 1.8 3 0 0 3 3 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 KIR60708.1 - 5.4e-06 26.4 0.9 1.2e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_34 PF13601.6 KIR60708.1 - 7.2e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 KIR60708.1 - 0.00019 21.3 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 KIR60708.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.6 KIR60708.1 - 0.0081 16.1 0.3 0.017 15.1 0.1 1.8 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain PadR PF03551.14 KIR60708.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_IclR PF09339.10 KIR60708.1 - 0.011 15.6 0.5 0.011 15.6 0.5 2.8 3 1 0 3 3 3 0 IclR helix-turn-helix domain B-block_TFIIIC PF04182.12 KIR60708.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MctB PF11382.8 KIR60708.1 - 0.015 15.0 0.3 0.018 14.7 0.3 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB GntR PF00392.21 KIR60708.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 KIR60708.1 - 0.028 14.4 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_CodY PF08222.11 KIR60708.1 - 0.038 13.6 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain Rrf2 PF02082.20 KIR60708.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 KIR60708.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SgrR_N PF12793.7 KIR60708.1 - 0.086 13.1 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Sugar transport-related sRNA regulator N-term DUF4423 PF14394.6 KIR60708.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Transketolase_C PF02780.20 KIR60709.1 - 1.3e-21 76.8 0.4 3.4e-21 75.4 0.4 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KIR60709.1 - 2.9e-21 76.0 0.0 5.9e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIR60709.1 - 1.7e-20 73.2 0.0 3.4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3052 PF11253.8 KIR60710.1 - 2.1e-53 179.5 1.4 2.5e-53 179.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) AhpC-TSA PF00578.21 KIR60711.1 - 1e-37 128.8 0.0 1.2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR60711.1 - 3.3e-23 82.0 0.0 3.9e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 KIR60711.1 - 0.00068 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Pectate_lyase PF03211.13 KIR60712.1 - 3e-73 245.7 8.2 7.5e-73 244.4 4.8 2.1 2 0 0 2 2 2 1 Pectate lyase F5_F8_type_C PF00754.25 KIR60712.1 - 9.2e-05 22.6 2.1 0.00019 21.6 0.4 2.2 2 0 0 2 2 2 1 F5/8 type C domain PT PF04886.12 KIR60712.1 - 0.96 9.0 13.7 2 8.0 13.7 1.4 1 0 0 1 1 1 0 PT repeat Abhydrolase_4 PF08386.10 KIR60713.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein CC PF04942.14 KIR60715.1 - 0.31 11.3 4.3 0.9 9.8 1.1 3.1 3 0 0 3 3 3 0 CC domain Abhydrolase_1 PF00561.20 KIR60716.1 - 8.2e-19 68.3 0.4 2e-18 67.0 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR60716.1 - 7e-16 59.5 19.1 8.6e-16 59.2 19.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR60716.1 - 1.6e-11 43.9 0.9 8.7e-11 41.5 0.4 1.9 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIR60716.1 - 5.9e-09 36.4 0.1 7e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KIR60716.1 - 2.7e-05 23.0 0.0 3.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KIR60716.1 - 0.003 17.3 0.1 0.0038 16.9 0.1 1.3 1 0 0 1 1 1 1 Putative esterase RibD_C PF01872.17 KIR60717.1 - 4.6e-10 39.7 0.0 2.1e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 KIR60717.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Dihydrofolate reductase PS_pyruv_trans PF04230.13 KIR60718.1 - 2.1e-44 152.6 0.0 2.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase DUF664 PF04978.12 KIR60720.1 - 2.6e-48 164.2 0.6 3e-48 164.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR60720.1 - 3.2e-11 43.8 0.4 4.3e-11 43.4 0.4 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 KIR60720.1 - 5.3e-05 23.2 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.8 KIR60720.1 - 0.00047 20.9 6.1 0.00068 20.3 6.1 1.2 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain PfkB PF00294.24 KIR60721.1 - 1.8e-27 96.4 0.9 7.1e-18 64.9 4.8 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PALP PF00291.25 KIR60721.1 - 0.0012 18.3 0.1 0.0012 18.3 0.1 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme SNF2_N PF00176.23 KIR60722.1 - 2.3e-57 194.3 0.0 3.6e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3670 PF12419.8 KIR60722.1 - 9e-42 142.2 4.2 9.8e-42 142.0 1.5 2.4 2 0 0 2 2 2 1 SNF2 Helicase protein Helicase_C PF00271.31 KIR60722.1 - 1.8e-13 50.8 0.0 2.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3040 PF11239.8 KIR60723.1 - 4.9e-14 52.4 0.7 5.9e-14 52.1 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) DUF1800 PF08811.11 KIR60724.1 - 8.1e-110 367.8 0.3 9.8e-110 367.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) DUF1501 PF07394.12 KIR60725.1 - 2.4e-26 92.7 0.5 4.3e-22 78.7 2.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1501) TAT_signal PF10518.9 KIR60725.1 - 6.1 6.8 15.1 0.14 12.1 6.3 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Ferric_reduct PF01794.19 KIR60726.1 - 1.7e-12 47.5 5.5 1.9e-12 47.4 3.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KIR60726.1 - 2.5e-10 41.0 0.0 4.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KIR60726.1 - 1.3e-06 28.4 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 KIR60726.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain FMN_bind PF04205.14 KIR60727.1 - 6e-06 26.7 0.3 1.2e-05 25.8 0.3 1.5 1 0 0 1 1 1 1 FMN-binding domain Prim-Pol PF09250.11 KIR60728.1 - 5.6e-17 62.6 5.5 7.1e-17 62.2 5.5 1.1 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal HTH_31 PF13560.6 KIR60729.1 - 7e-10 39.1 0.6 5.6e-09 36.2 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR60729.1 - 4.8e-06 26.5 0.0 8.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR60729.1 - 0.00041 20.4 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix Flavoprotein PF02441.19 KIR60730.1 - 3.7e-19 69.0 0.0 4.6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein NIF3 PF01784.18 KIR60731.1 - 1.2e-66 224.9 0.0 1.5e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) FlpD PF02662.16 KIR60731.1 - 0.039 14.0 0.1 0.072 13.1 0.1 1.3 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit PGA_cap PF09587.10 KIR60731.1 - 0.048 13.1 0.2 0.11 11.9 0.1 1.6 1 1 1 2 2 2 0 Bacterial capsule synthesis protein PGA_cap zf-RING_7 PF02591.15 KIR60732.1 - 2.3e-10 40.5 2.6 5.7e-10 39.2 2.6 1.7 1 0 0 1 1 1 1 C4-type zinc ribbon domain V_ATPase_I PF01496.19 KIR60732.1 - 0.0063 14.5 2.0 0.0077 14.2 2.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 KIR60732.1 - 0.018 15.2 4.0 0.018 15.2 4.0 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GP57 PF17594.2 KIR60732.1 - 0.021 14.6 0.2 0.94 9.3 0.4 2.7 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 DUF4407 PF14362.6 KIR60732.1 - 0.092 12.1 12.3 0.13 11.6 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ISG65-75 PF11727.8 KIR60732.1 - 0.41 9.8 2.5 0.83 8.8 2.0 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein BRE1 PF08647.11 KIR60732.1 - 0.51 10.4 10.4 4.4 7.5 0.5 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 KIR60732.1 - 0.55 10.4 19.2 1.3 9.2 18.8 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc24 PF08286.11 KIR60732.1 - 1.4 9.2 7.2 10 6.4 1.2 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 KIR60732.1 - 8.7 5.1 17.9 1.1 8.1 3.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 KIR60732.1 - 9.8 6.5 15.6 0.87 9.9 3.4 3.4 1 1 2 3 3 3 0 ABC transporter C-terminal domain His_Phos_1 PF00300.22 KIR60733.1 - 5e-55 186.2 0.6 5e-55 186.2 0.6 2.2 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) RVT_3 PF13456.6 KIR60733.1 - 1e-27 96.4 0.1 2e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 KIR60733.1 - 3.7e-08 33.7 0.0 6.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNase H RecC_C PF17946.1 KIR60733.1 - 0.024 14.4 0.3 0.05 13.4 0.3 1.7 1 0 0 1 1 1 0 RecC C-terminal domain DUF3311 PF11755.8 KIR60734.1 - 1e-12 47.8 2.3 1.2e-12 47.6 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) MFS_2 PF13347.6 KIR60734.1 - 0.016 13.8 0.2 0.016 13.8 0.2 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein SSF PF00474.17 KIR60735.1 - 6.9e-20 71.3 20.6 1.1e-19 70.6 20.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family MarR PF01047.22 KIR60736.1 - 2.7e-14 52.8 0.0 6.6e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR60736.1 - 5.9e-12 45.3 1.9 7e-12 45.1 0.7 1.9 2 1 0 2 2 2 1 MarR family HTH_27 PF13463.6 KIR60736.1 - 2.5e-10 40.7 0.0 1.9e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 KIR60736.1 - 6.6e-07 28.8 0.0 9.9e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KIR60736.1 - 5.5e-06 26.3 0.3 5.5e-06 26.3 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KIR60736.1 - 6.8e-05 22.6 0.9 0.00014 21.6 0.2 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 KIR60736.1 - 9.2e-05 22.6 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 KIR60736.1 - 0.00025 21.0 2.3 0.0046 16.9 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn helix HTH_Crp_2 PF13545.6 KIR60736.1 - 0.00049 20.0 0.3 0.0021 18.0 0.1 2.1 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR60736.1 - 0.00099 18.9 0.6 0.004 16.9 0.2 2.3 1 1 1 2 2 2 1 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KIR60736.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 KIR60736.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 KIR60736.1 - 0.06 13.5 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HxlR PF01638.17 KIR60736.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix MFS_1 PF07690.16 KIR60737.1 - 1.9e-31 109.3 52.1 1.9e-31 109.3 52.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1774 PF08611.10 KIR60737.1 - 0.0051 17.1 0.8 0.021 15.1 0.0 2.4 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) TauE PF01925.19 KIR60738.1 - 2.8e-36 125.3 41.9 3.4e-36 125.1 41.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phage_AlpA PF05930.12 KIR60739.1 - 0.00045 20.0 0.3 0.0007 19.4 0.3 1.4 1 1 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.7 KIR60739.1 - 0.068 13.4 0.2 0.29 11.3 0.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain Herpes_US12 PF05363.12 KIR60740.1 - 0.019 15.7 0.1 0.03 15.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus US12 family TetR_C_1 PF02909.17 KIR60741.1 - 4.1e-13 49.4 0.0 6.4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR60741.1 - 2.2e-09 36.9 1.5 1.8e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_24 PF13412.6 KIR60741.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HAD_2 PF13419.6 KIR60742.1 - 8.4e-16 58.6 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR60742.1 - 1.4e-10 41.8 0.3 2.6e-10 40.9 0.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR60742.1 - 3.5e-09 36.6 0.6 3.5e-09 36.6 0.6 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KIR60742.1 - 1.6e-07 31.9 0.6 2.4e-07 31.3 0.6 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RHH_1 PF01402.21 KIR60743.1 - 1.5e-06 27.9 1.3 3.2e-06 26.9 0.7 1.9 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family RHH_5 PF07878.11 KIR60743.1 - 1.6e-05 24.7 2.9 4.1e-05 23.4 0.4 2.3 2 0 0 2 2 2 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicB PF05534.12 KIR60743.1 - 3.1e-05 23.7 0.6 7.5e-05 22.5 0.6 1.6 1 0 0 1 1 1 1 HicB family DUF1778 PF08681.11 KIR60743.1 - 7.4e-05 22.6 0.7 0.00018 21.4 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) Arc PF03869.14 KIR60743.1 - 0.00018 21.3 0.1 0.00035 20.3 0.1 1.5 1 0 0 1 1 1 1 Arc-like DNA binding domain HicB_lk_antitox PF15919.5 KIR60743.1 - 0.039 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system DUF4097 PF13349.6 KIR60744.1 - 1.3e-13 50.9 0.5 1.7e-13 50.5 0.5 1.1 1 0 0 1 1 1 1 Putative adhesin DUF3253 PF11625.8 KIR60744.1 - 0.17 12.1 1.0 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) TT_ORF2a PF08197.11 KIR60744.1 - 1.5 8.9 5.0 2.7 8.1 0.5 3.0 3 0 0 3 3 3 0 pORF2a truncated protein ABC_tran PF00005.27 KIR60745.1 - 1.2e-26 93.9 0.0 1.9e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR60745.1 - 2.9e-14 53.6 1.6 1.6e-09 38.0 0.0 2.4 1 1 2 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KIR60745.1 - 1e-06 29.4 0.0 1.9e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) KdpD PF02702.17 KIR60745.1 - 0.00042 19.9 0.0 0.00095 18.7 0.0 1.8 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain SRP54 PF00448.22 KIR60745.1 - 0.0019 17.8 0.2 0.003 17.2 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KIR60745.1 - 0.0051 17.2 0.9 0.0096 16.3 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIR60745.1 - 0.011 16.0 0.1 0.078 13.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIR60745.1 - 0.015 15.0 1.0 0.036 13.8 1.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIR60745.1 - 0.022 15.2 0.0 0.11 13.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIR60745.1 - 0.023 14.4 0.2 0.055 13.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR60745.1 - 0.026 15.0 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIR60745.1 - 0.027 14.7 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KIR60745.1 - 0.041 14.1 0.0 0.094 13.0 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KIR60745.1 - 0.044 13.5 0.0 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 KIR60745.1 - 0.11 12.3 0.1 0.27 11.0 0.2 1.6 2 0 0 2 2 2 0 MukB N-terminal DUF87 PF01935.17 KIR60745.1 - 0.18 11.8 0.1 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain BCA_ABC_TP_C PF12399.8 KIR60745.1 - 0.23 11.4 2.3 0.61 10.1 0.1 2.6 3 0 0 3 3 2 0 Branched-chain amino acid ATP-binding cassette transporter ABC2_membrane PF01061.24 KIR60746.1 - 3.5e-25 88.7 16.4 4.5e-25 88.3 16.4 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR60746.1 - 1.2e-13 50.9 7.8 1.2e-13 50.9 7.8 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF4259 PF14078.6 KIR60747.1 - 9.6e-06 26.4 0.1 1.6e-05 25.7 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4259) Peptidase_S8 PF00082.22 KIR60749.1 - 1e-35 123.4 23.3 2e-35 122.5 23.3 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIR60749.1 - 1.2e-08 35.5 0.0 2.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 S8_pro-domain PF16470.5 KIR60749.1 - 0.12 13.2 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase S8 pro-domain NTP_transf_2 PF01909.23 KIR60750.1 - 0.0073 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIR60750.1 - 0.099 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF4111 PF13427.6 KIR60750.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4111) Robl_LC7 PF03259.17 KIR60751.1 - 1.7e-15 56.5 0.3 7.7e-15 54.4 0.0 1.9 1 1 1 2 2 2 2 Roadblock/LC7 domain HC2 PF07382.11 KIR60753.1 - 0.00058 20.0 148.0 0.016 15.3 79.9 2.2 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 RNB PF00773.19 KIR60754.1 - 1e-39 136.8 0.0 1.4e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain RNase_II_C_S1 PF18614.1 KIR60754.1 - 1.1e-18 66.9 4.6 1.1e-18 66.9 4.6 3.7 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain F420_oxidored PF03807.17 KIR60755.1 - 1.2e-21 77.1 0.9 2.1e-21 76.3 0.9 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KIR60755.1 - 9.3e-05 22.9 0.3 0.00015 22.2 0.3 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KIR60755.1 - 0.00013 21.9 3.5 0.00013 21.9 3.5 2.2 1 1 1 2 2 2 1 Rossmann-like domain NAD_binding_2 PF03446.15 KIR60755.1 - 0.00013 22.1 0.1 0.00021 21.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KIR60755.1 - 0.00024 20.5 1.5 0.00095 18.6 0.6 2.2 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIR60755.1 - 0.0004 20.4 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 KIR60755.1 - 0.0017 17.8 0.9 0.0026 17.2 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase IlvN PF07991.12 KIR60755.1 - 0.0034 17.0 0.7 0.0096 15.5 0.7 1.8 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KIR60755.1 - 0.0035 17.2 1.0 0.0052 16.7 1.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KIR60755.1 - 0.03 14.2 0.4 0.057 13.3 0.4 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 KIR60755.1 - 0.046 14.0 0.3 0.099 12.9 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KIR60755.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3306 PF11748.8 KIR60756.1 - 0.98 10.3 9.7 0.15 13.0 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) KCT2 PF17818.1 KIR60756.1 - 4 7.5 7.4 1 9.4 3.8 1.6 1 1 1 2 2 2 0 Keratinocyte-associated gene product Pantoate_transf PF02548.15 KIR60757.1 - 8.4e-104 346.5 0.1 9.6e-104 346.4 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KIR60757.1 - 5.8e-06 25.9 1.0 3.4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NAD_synthase PF02540.17 KIR60758.1 - 1.9e-65 220.3 0.0 2.7e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 KIR60758.1 - 1.9e-27 96.2 0.0 2.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.21 KIR60758.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 KIR60758.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIR60758.1 - 0.061 12.1 0.1 0.09 11.6 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Gln-synt_C PF00120.24 KIR60759.1 - 7.5e-123 409.9 0.0 8.8e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KIR60759.1 - 2.8e-26 91.0 0.1 7.7e-26 89.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 KIR60759.1 - 0.014 15.3 0.0 0.13 12.1 0.0 2.2 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain DUF350 PF03994.14 KIR60760.1 - 6.5e-32 109.5 11.0 7.2e-17 61.3 0.7 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) WYL PF13280.6 KIR60761.1 - 1e-14 54.9 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 KIR60761.1 - 3.4e-11 42.9 0.0 6.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 KIR60761.1 - 0.0084 16.4 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.12 KIR60761.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Lipase PF00151.19 KIR60761.1 - 0.14 11.5 0.4 0.19 11.0 0.4 1.1 1 0 0 1 1 1 0 Lipase Glyoxalase_6 PF18029.1 KIR60762.1 - 5.5e-09 36.8 0.3 9.4e-09 36.0 0.3 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KIR60762.1 - 4.3e-07 30.2 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Not3 PF04065.15 KIR60763.1 - 0.00045 19.7 0.4 0.00055 19.4 0.4 1.0 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component HTH_10 PF04967.12 KIR60763.1 - 0.0017 18.1 0.2 0.67 9.8 0.1 2.7 2 0 0 2 2 2 1 HTH DNA binding domain DUF2680 PF10925.8 KIR60763.1 - 0.0031 17.5 0.3 0.008 16.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2680) Sigma70_ner PF04546.13 KIR60763.1 - 0.0097 15.8 3.1 0.012 15.5 3.1 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Phage_XkdX PF09693.10 KIR60763.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) DUF1707 PF08044.11 KIR60763.1 - 0.026 14.6 0.7 0.076 13.1 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) DUF2126 PF09899.9 KIR60763.1 - 0.045 11.8 0.8 0.053 11.6 0.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) U1snRNP70_N PF12220.8 KIR60763.1 - 0.067 13.8 2.7 0.13 12.9 0.0 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Arg_decarbox_C PF17944.1 KIR60763.1 - 0.086 13.4 0.3 0.2 12.2 0.3 1.6 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension Mu-like_Pro PF10123.9 KIR60763.1 - 0.13 11.8 6.4 0.4 10.2 6.4 1.6 1 1 0 1 1 1 0 Mu-like prophage I protein FUSC PF04632.12 KIR60763.1 - 0.19 10.2 0.6 0.27 9.7 0.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family 3HCDH_N PF02737.18 KIR60763.1 - 0.27 11.1 4.3 7.5 6.4 0.2 2.1 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain N36 PF11438.8 KIR60763.1 - 0.62 9.9 0.1 0.62 9.9 0.1 2.7 3 0 0 3 3 3 0 36-mer N-terminal peptide of the N protein (N36) DUF3292 PF11696.8 KIR60763.1 - 0.99 7.7 5.3 1.2 7.4 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FliE PF02049.18 KIR60763.1 - 2.6 8.3 5.8 4.8 7.4 0.4 2.2 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE SGL PF08450.12 KIR60764.1 - 4.2e-11 42.9 6.4 0.0082 15.7 0.2 4.8 2 2 3 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region DUF2255 PF10012.9 KIR60764.1 - 0.069 13.3 0.4 35 4.6 0.0 3.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2255) NHL PF01436.21 KIR60764.1 - 0.46 10.6 9.3 2.9 8.1 0.0 4.9 5 0 0 5 5 5 0 NHL repeat GlnE PF03710.15 KIR60765.1 - 8.2e-88 294.0 15.4 2.4e-40 138.5 0.8 3.6 3 1 0 3 3 3 3 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 KIR60765.1 - 3.6e-58 195.8 1.8 7.1e-37 126.7 0.1 2.7 2 0 0 2 2 2 2 GlnD PII-uridylyltransferase DUF294 PF03445.13 KIR60765.1 - 4.4e-07 29.8 0.1 0.0096 15.7 0.0 2.5 2 0 0 2 2 2 2 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 KIR60765.1 - 0.00019 21.2 0.2 0.31 10.8 0.0 2.7 2 0 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain GT87 PF09594.10 KIR60767.1 - 8.6e-06 25.6 45.7 8.6e-06 25.6 45.7 4.1 2 1 2 4 4 4 2 Glycosyltransferase family 87 DUF5316 PF17247.2 KIR60767.1 - 0.075 13.1 0.6 3.9 7.6 0.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Gln-synt_C PF00120.24 KIR60768.1 - 1.2e-130 435.6 0.0 1.4e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KIR60768.1 - 9.2e-27 92.6 0.2 1.9e-26 91.6 0.2 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4191 PF13829.6 KIR60769.1 - 1e-73 247.4 2.5 1.2e-73 247.1 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) FA_desaturase PF00487.24 KIR60769.1 - 0.098 12.5 3.1 0.13 12.0 3.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Trp_oprn_chp PF09534.10 KIR60769.1 - 0.22 11.3 8.2 0.3 10.8 8.2 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3742 PF12553.8 KIR60769.1 - 0.34 11.0 2.0 0.57 10.3 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Amino_oxidase PF01593.24 KIR60770.1 - 8.4e-22 78.1 0.1 2.1e-11 43.8 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR60770.1 - 3.8e-15 55.9 0.2 1.3e-14 54.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR60770.1 - 1.1e-08 35.1 4.4 1.1e-07 31.7 4.4 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIR60770.1 - 7.5e-07 28.8 0.2 0.0037 16.7 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR60770.1 - 3.1e-06 26.6 0.2 4.3e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR60770.1 - 3.3e-06 26.6 0.1 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR60770.1 - 5.4e-05 22.1 0.1 0.00018 20.4 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KIR60770.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIR60770.1 - 0.00021 20.7 0.1 0.00048 19.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR60770.1 - 0.001 19.6 0.0 0.031 14.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIR60770.1 - 0.0016 17.8 0.1 0.027 13.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KIR60770.1 - 0.0017 18.4 0.7 0.13 12.2 0.1 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIR60770.1 - 0.0028 16.8 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KIR60770.1 - 0.0089 15.1 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GLF PF03275.13 KIR60770.1 - 0.0098 15.6 0.4 0.33 10.6 0.0 2.3 2 0 0 2 2 2 1 UDP-galactopyranose mutase tRNA-synt_2 PF00152.20 KIR60771.1 - 9.8e-69 231.8 0.0 1.4e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIR60771.1 - 2.6e-13 49.8 0.0 4.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Glyoxalase PF00903.25 KIR60772.1 - 1.2e-14 54.6 0.0 1.4e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR60772.1 - 1.9e-10 41.5 0.8 2.3e-10 41.2 0.8 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIR60772.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KIR60772.1 - 0.0017 18.5 0.5 0.021 14.9 0.3 2.1 1 1 1 2 2 2 2 Glyoxalase-like domain DUF2079 PF09852.9 KIR60773.1 - 4.2e-06 25.9 21.8 8.8e-06 24.8 21.8 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2079) PTPS_related PF10131.9 KIR60773.1 - 1.6 7.0 14.5 1.3 7.2 11.3 2.2 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Esterase_phd PF10503.9 KIR60774.1 - 5.6e-32 111.0 5.4 5.6e-32 111.0 5.4 2.0 2 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR60774.1 - 3.6e-09 36.4 0.0 1.1e-08 34.8 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIR60774.1 - 0.0011 18.7 0.8 0.0025 17.5 0.6 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KIR60774.1 - 0.0021 17.8 0.9 0.0046 16.6 0.9 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KIR60774.1 - 0.037 13.8 0.5 0.094 12.5 0.5 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KIR60774.1 - 0.044 13.6 0.5 0.044 13.6 0.5 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 KIR60774.1 - 0.062 12.9 0.0 0.3 10.7 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF1731 PF08338.11 KIR60775.1 - 1.2e-14 53.8 0.7 2.8e-14 52.6 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 KIR60775.1 - 2.6e-09 36.9 0.1 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR60775.1 - 1.7e-06 28.0 0.5 3.1e-06 27.2 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIR60775.1 - 0.00093 18.4 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KIR60775.1 - 0.029 13.9 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KIR60775.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Aldo_ket_red PF00248.21 KIR60776.1 - 3.1e-56 190.7 0.0 3.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MerR_1 PF13411.6 KIR60777.1 - 2.5e-14 53.1 0.1 7.4e-14 51.6 0.0 1.8 2 1 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 KIR60777.1 - 8.6e-11 41.4 2.3 1.5e-09 37.4 0.3 2.4 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KIR60777.1 - 1.1e-08 35.5 1.7 4.6e-07 30.3 1.2 2.1 2 0 0 2 2 2 1 MerR, DNA binding NBP1 PF08537.10 KIR60777.1 - 0.14 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DinB_2 PF12867.7 KIR60778.1 - 7.4e-21 75.0 8.5 1.1e-20 74.5 8.5 1.2 1 0 0 1 1 1 1 DinB superfamily GntR PF00392.21 KIR60779.1 - 2.5e-18 65.5 0.0 2.8e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 KIR60779.1 - 0.0092 16.3 0.0 0.0096 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_41 PF14502.6 KIR60779.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain PaaX PF07848.12 KIR60779.1 - 0.068 13.4 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein HTH_17 PF12728.7 KIR60780.1 - 2.7e-13 49.9 0.0 4.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 KIR60780.1 - 0.0036 17.0 0.7 0.017 14.9 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_Crp_2 PF13545.6 KIR60780.1 - 0.0092 15.9 0.7 0.051 13.5 0.1 2.4 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_37 PF13744.6 KIR60780.1 - 0.013 15.5 0.2 0.049 13.6 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR60780.1 - 0.014 15.1 0.0 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.6 KIR60780.1 - 0.022 15.1 0.7 0.062 13.6 0.7 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain AbiEi_4 PF13338.6 KIR60780.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin MerR PF00376.23 KIR60780.1 - 0.056 13.2 0.4 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 MerR family regulatory protein DUF134 PF02001.16 KIR60780.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF134 Bac_luciferase PF00296.20 KIR60781.1 - 1.5e-39 136.3 23.7 2.9e-39 135.3 21.5 2.1 1 1 1 2 2 2 1 Luciferase-like monooxygenase LtrA PF06772.11 KIR60782.1 - 6.2e-79 265.8 39.4 7.5e-79 265.5 39.4 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) 2-oxoacid_dh PF00198.23 KIR60783.1 - 3.8e-71 239.2 0.0 5.4e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIR60783.1 - 9.5e-42 140.7 9.7 6.9e-21 73.9 0.9 3.1 3 0 0 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.17 KIR60783.1 - 4.3e-15 55.8 0.9 1.7e-14 53.8 0.4 2.5 2 0 0 2 2 2 1 e3 binding domain GCV_H PF01597.19 KIR60783.1 - 0.0003 20.7 5.8 0.064 13.2 0.2 3.4 3 0 0 3 3 3 2 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 KIR60783.1 - 0.0012 18.6 0.9 1.6 8.6 0.0 3.6 2 1 1 3 3 3 2 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 KIR60783.1 - 0.025 14.4 1.2 12 5.6 0.0 3.5 3 1 1 4 4 4 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 KIR60783.1 - 0.025 14.2 0.2 8.6 6.1 0.0 3.6 4 0 0 4 4 4 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_3 PF13437.6 KIR60783.1 - 0.052 14.2 9.7 5.3 7.8 0.5 4.3 3 2 1 4 4 4 0 HlyD family secretion protein Stomoxyn PF11585.8 KIR60783.1 - 3.4 7.8 9.5 10 6.2 0.9 2.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Pyr_redox_2 PF07992.14 KIR60784.1 - 1.4e-65 221.4 5.3 1.7e-65 221.1 5.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIR60784.1 - 3.4e-26 91.6 0.1 7.8e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIR60784.1 - 7.4e-18 64.9 6.7 1.2e-17 64.2 0.5 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR60784.1 - 1.2e-10 41.1 4.3 1.1e-07 31.4 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR60784.1 - 1.8e-08 33.9 5.1 1.6e-07 30.8 1.6 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIR60784.1 - 2.5e-06 26.4 6.4 0.027 13.2 0.0 3.4 3 1 1 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 KIR60784.1 - 2.7e-06 27.0 1.9 5.3e-06 26.0 1.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KIR60784.1 - 9.8e-05 22.3 1.5 0.00061 19.7 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KIR60784.1 - 0.00036 19.8 0.8 0.00036 19.8 0.8 2.6 4 0 0 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 KIR60784.1 - 0.0004 20.6 4.2 0.089 13.0 1.5 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIR60784.1 - 0.00085 18.7 3.5 0.037 13.3 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KIR60784.1 - 0.0035 17.0 3.8 0.0035 17.0 3.8 4.0 2 2 1 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIR60784.1 - 0.018 14.3 0.1 0.11 11.7 0.0 2.1 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIR60784.1 - 0.03 13.4 6.5 2.7 6.9 1.0 3.2 2 1 1 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KIR60784.1 - 0.064 12.6 0.3 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_17 PF12692.7 KIR60784.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Trp_halogenase PF04820.14 KIR60784.1 - 2.3 7.0 5.8 0.14 11.0 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KIR60784.1 - 7.7 5.7 7.0 9.4 5.4 0.3 2.7 2 1 1 3 3 3 0 FAD binding domain Glyco_transf_11 PF01531.16 KIR60785.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 11 Peptidase_M17 PF00883.21 KIR60786.1 - 2e-110 368.9 0.3 2e-110 368.9 0.3 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIR60786.1 - 3.9e-22 78.4 0.6 3.9e-22 78.4 0.6 2.8 2 1 2 4 4 4 1 Cytosol aminopeptidase family, N-terminal domain LPD7 PF18821.1 KIR60786.1 - 0.24 11.5 3.1 0.19 11.9 0.6 2.1 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 7 GCV_T PF01571.21 KIR60787.1 - 3.4e-85 285.5 0.1 4.2e-85 285.2 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIR60787.1 - 6.9e-18 64.3 0.1 1.6e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KIR60787.1 - 7e-05 23.0 0.1 0.00032 20.9 0.0 2.1 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family POPLD PF08170.12 KIR60787.1 - 0.072 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 POPLD (NUC188) domain DUF2314 PF10077.9 KIR60788.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) DBI_PRT PF02277.17 KIR60789.1 - 5.6e-67 226.3 14.3 5.6e-67 226.3 14.3 1.7 2 0 0 2 2 2 1 Phosphoribosyltransferase CobU PF02283.16 KIR60789.1 - 1.6e-47 161.2 0.0 2.9e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Peptidase_M50 PF02163.22 KIR60790.1 - 2.6e-07 30.2 10.4 0.00016 21.1 1.3 3.1 2 1 1 3 3 3 3 Peptidase family M50 Trp_oprn_chp PF09534.10 KIR60790.1 - 0.028 14.2 0.6 0.028 14.2 0.6 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Aldo_ket_red PF00248.21 KIR60791.1 - 4.7e-75 252.5 0.0 5.3e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC2_membrane_6 PF06182.11 KIR60792.1 - 1.1e-10 41.7 0.2 1.2e-10 41.5 0.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_6 PF06182.11 KIR60793.1 - 5.1e-42 144.2 0.9 5.8e-42 144.0 0.9 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3043 PF11241.8 KIR60794.1 - 4.1e-43 147.4 1.5 5.9e-43 146.9 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) EPSP_synthase PF00275.20 KIR60795.1 - 1.6e-54 185.2 0.0 1.9e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) NadA PF02445.16 KIR60796.1 - 2.9e-106 355.0 0.0 4.1e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Quinolinate synthetase A protein Gly_kinase PF02595.15 KIR60797.1 - 1.1e-114 383.2 10.1 1.3e-114 383.1 10.1 1.0 1 0 0 1 1 1 1 Glycerate kinase family Fe-S_biosyn PF01521.20 KIR60798.1 - 5.7e-19 68.4 0.0 6.4e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PfkB PF00294.24 KIR60799.1 - 1.3e-39 136.3 0.1 1.6e-39 136.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TusA PF01206.17 KIR60800.1 - 3.4e-21 74.8 0.0 4e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA Aminotran_5 PF00266.19 KIR60801.1 - 3e-39 135.0 0.0 1.4e-38 132.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIR60801.1 - 4.7e-06 26.1 0.1 7.8e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase COX2 PF00116.20 KIR60802.1 - 3.8e-17 62.3 0.2 1.4e-16 60.5 0.2 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 KIR60802.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DctQ PF04290.12 KIR60802.1 - 0.033 14.1 2.2 0.084 12.8 1.2 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_3_6 PF07332.11 KIR60802.1 - 0.077 13.0 0.7 0.14 12.2 0.2 1.6 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III bMG6 PF17962.1 KIR60802.1 - 0.081 13.1 0.1 0.49 10.6 0.2 2.0 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 Cyt_c_ox_IV PF12270.8 KIR60803.1 - 2.6e-47 160.2 4.8 3e-47 160.1 4.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Yip1 PF04893.17 KIR60803.1 - 0.036 13.8 13.0 0.051 13.3 13.0 1.2 1 0 0 1 1 1 0 Yip1 domain DUF4231 PF14015.6 KIR60803.1 - 0.12 12.9 2.5 1.3 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4131 PF13567.6 KIR60803.1 - 0.12 12.0 13.3 0.58 9.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3153 PF11353.8 KIR60803.1 - 0.27 10.8 1.5 0.42 10.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) EI24 PF07264.11 KIR60803.1 - 3.8 7.7 12.3 13 5.9 12.3 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Glycos_transf_3 PF00591.21 KIR60805.1 - 1.3e-80 270.6 0.4 1.7e-80 270.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIR60805.1 - 5.5e-19 67.8 0.8 5.5e-19 67.8 0.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Response_reg PF00072.24 KIR60806.1 - 0.0011 19.1 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_M23 PF01551.22 KIR60806.1 - 0.18 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M23 Caa3_CtaG PF09678.10 KIR60807.1 - 3.3e-76 255.8 27.1 4.3e-76 255.4 27.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) COX3 PF00510.18 KIR60808.1 - 1.1e-23 84.4 16.4 1.5e-23 84.0 16.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Jagunal PF07086.12 KIR60808.1 - 0.00097 19.3 1.7 0.00097 19.3 1.7 1.6 1 1 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis Cytochrome_CBB3 PF13442.6 KIR60809.1 - 4.1e-23 81.5 0.1 3.2e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KIR60809.1 - 1.3e-13 51.9 3.6 2.3e-05 25.4 0.1 3.9 2 2 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 KIR60809.1 - 0.00046 19.9 0.2 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KIR60809.1 - 0.0093 15.6 0.2 1.2 8.7 0.0 2.9 3 0 0 3 3 3 1 Photosystem P840 reaction-centre cytochrome c-551 CCP_MauG PF03150.14 KIR60809.1 - 0.0095 16.6 0.0 0.8 10.3 0.0 2.2 2 0 0 2 2 2 1 Di-haem cytochrome c peroxidase DUF2157 PF09925.9 KIR60809.1 - 0.026 14.3 0.3 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF1924 PF09086.11 KIR60809.1 - 0.028 14.8 0.1 4.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) Cytochrome_C554 PF13435.6 KIR60809.1 - 0.038 14.9 0.1 1.1 10.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Haem_bd PF14376.6 KIR60809.1 - 0.051 13.5 0.0 7.1 6.6 0.0 3.4 4 0 0 4 4 4 0 Haem-binding domain MHC2-interact PF09307.10 KIR60809.1 - 0.18 11.8 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 CLIP, MHC2 interacting MCR PF18509.1 KIR60809.1 - 2.1 8.0 4.8 0.93 9.1 0.3 2.3 2 0 0 2 2 2 0 Magnetochrome domain Rieske PF00355.26 KIR60810.1 - 5.5e-09 35.8 0.1 9.6e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LtrA PF06772.11 KIR60810.1 - 0.064 12.5 2.4 3.6 6.7 0.0 2.1 1 1 1 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) Cytochrom_B_N_2 PF13631.6 KIR60811.1 - 3.1e-60 203.0 5.5 3.1e-60 203.0 5.5 2.0 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 KIR60811.1 - 6.1e-29 101.2 12.6 4.4e-27 95.1 12.6 2.2 1 1 0 1 1 1 1 Cytochrome b/b6/petB DUF4405 PF14358.6 KIR60811.1 - 3.2e-05 24.4 7.0 3.2e-05 24.4 7.0 4.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4405) DUF4142 PF13628.6 KIR60812.1 - 4.2e-37 127.5 13.1 5.8e-37 127.0 12.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4142) DUF305 PF03713.13 KIR60812.1 - 6.7e-07 29.6 5.5 1.8e-06 28.2 3.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF305) CBM27 PF09212.10 KIR60812.1 - 0.0071 16.6 0.0 0.0091 16.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding module 27 TPPK_C PF12555.8 KIR60812.1 - 0.034 14.2 0.5 0.082 13.0 0.5 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Mucin PF01456.17 KIR60812.1 - 0.044 13.8 13.7 0.045 13.7 0.3 2.6 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF732 PF05305.14 KIR60812.1 - 1.2 9.5 12.8 11 6.5 12.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF732) AsnC_trans_reg PF01037.21 KIR60813.1 - 3.5e-16 58.9 0.1 4.3e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 KIR60813.1 - 5.2e-05 23.2 1.5 6.7e-05 22.9 1.5 1.1 1 0 0 1 1 1 1 NapD protein AsnC_trans_reg2 PF17805.1 KIR60813.1 - 0.099 12.8 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 AsnC-like ligand binding domain NUDIX PF00293.28 KIR60814.1 - 2e-16 60.2 0.1 2.7e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain HD_4 PF13328.6 KIR60815.1 - 1.1e-41 142.2 1.2 2e-41 141.3 1.2 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 KIR60815.1 - 3.5e-17 62.8 0.0 6.8e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 KIR60815.1 - 3.1e-15 56.0 0.0 7.1e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain HD PF01966.22 KIR60815.1 - 2.7e-14 53.5 1.8 5e-12 46.1 0.7 3.3 3 0 0 3 3 3 1 HD domain ThiS PF02597.20 KIR60815.1 - 0.0053 17.4 0.1 0.019 15.6 0.1 2.0 1 0 0 1 1 1 1 ThiS family UreF PF01730.16 KIR60815.1 - 0.035 14.7 0.0 0.13 12.9 0.0 2.0 1 0 0 1 1 1 0 UreF HTH_AraC PF00165.23 KIR60815.1 - 0.2 11.8 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DprA_WH PF17782.1 KIR60815.1 - 0.34 11.1 3.2 0.27 11.4 0.6 2.3 2 0 0 2 2 2 0 DprA winged helix domain NYN_YacP PF05991.11 KIR60816.1 - 1.3e-21 77.2 0.0 1e-20 74.4 0.0 2.2 2 0 0 2 2 2 1 YacP-like NYN domain Trypan_PARP PF05887.11 KIR60816.1 - 0.0016 18.4 18.9 0.0043 17.0 18.9 1.8 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CENP-H PF05837.12 KIR60816.1 - 0.057 13.8 7.0 0.11 12.9 7.0 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) betaPIX_CC PF16523.5 KIR60816.1 - 0.33 10.8 2.3 0.67 9.8 2.3 1.5 1 0 0 1 1 1 0 betaPIX coiled coil Spc7 PF08317.11 KIR60816.1 - 2.4 7.0 7.8 3.8 6.3 7.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DLP_helical PF18709.1 KIR60816.1 - 2.4 7.3 6.4 1.2 8.2 4.2 1.5 1 1 1 2 2 2 0 Dynamin-like helical domain DUF4200 PF13863.6 KIR60816.1 - 3.6 8.0 11.0 0.4 11.1 5.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF2968 PF11180.8 KIR60816.1 - 4 7.0 24.1 0.026 14.1 12.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Peptidase_M48 PF01435.18 KIR60817.1 - 1.6e-26 93.3 0.0 2.5e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KIR60817.1 - 3.5e-15 56.4 0.1 6.6e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 KIR60817.1 - 0.018 14.3 0.0 0.054 12.7 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2268 PF10026.9 KIR60817.1 - 0.031 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Wzy_C PF04932.15 KIR60817.1 - 0.035 13.7 0.7 0.035 13.7 0.7 3.5 3 1 0 3 3 3 0 O-Antigen ligase Glycos_transf_1 PF00534.20 KIR60818.1 - 7.3e-41 139.6 0.0 1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR60818.1 - 2.6e-33 115.3 0.1 4.3e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIR60818.1 - 1.7e-12 47.5 0.0 4.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR60818.1 - 1e-07 32.1 4.9 2.5e-07 30.9 4.9 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Methyltransf_19 PF04672.12 KIR60819.1 - 1.5e-101 339.4 1.9 1.7e-101 339.3 1.9 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_12 PF08242.12 KIR60819.1 - 3e-06 27.9 0.0 5.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR60819.1 - 0.00024 20.9 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR60819.1 - 0.00036 20.4 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR60819.1 - 0.0026 18.4 0.1 0.0092 16.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR60819.1 - 0.013 16.1 0.0 0.079 13.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIR60819.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HAD_SAK_2 PF18143.1 KIR60819.1 - 0.086 13.1 0.1 0.21 11.9 0.0 1.7 1 1 1 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins NodS PF05401.11 KIR60819.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 KIR60819.1 - 0.1 11.8 0.0 2.8 7.0 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Response_reg PF00072.24 KIR60820.1 - 1.5e-24 86.3 0.0 2.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR60820.1 - 9.3e-19 66.7 0.0 1.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR60820.1 - 1.6e-06 27.7 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR60820.1 - 0.00014 21.6 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KIR60820.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 KIR60820.1 - 0.0012 18.8 0.5 0.014 15.4 0.0 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 KIR60820.1 - 0.0028 18.1 0.0 0.0062 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR60820.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 KIR60820.1 - 0.005 16.6 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_7 PF02796.15 KIR60820.1 - 0.0058 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KIR60820.1 - 0.0071 16.4 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KIR60820.1 - 0.0086 16.0 0.1 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 HTH domain HTH_5 PF01022.20 KIR60820.1 - 0.0097 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_38 PF13936.6 KIR60820.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 KIR60820.1 - 0.02 14.8 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 KIR60820.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF742 PF05331.11 KIR60820.1 - 0.034 13.9 0.2 0.078 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_10 PF04967.12 KIR60820.1 - 0.037 13.8 0.6 0.67 9.8 0.1 3.0 4 0 0 4 4 3 0 HTH DNA binding domain Mga PF05043.13 KIR60820.1 - 0.19 12.3 0.0 0.32 11.6 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain HisKA_3 PF07730.13 KIR60821.1 - 3.2e-14 53.2 0.8 3.2e-14 53.2 0.8 3.4 4 0 0 4 4 4 1 Histidine kinase GAF_3 PF13492.6 KIR60821.1 - 4.1e-10 40.1 0.7 9.5e-10 38.9 0.7 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 KIR60821.1 - 2.6e-07 31.1 0.0 1.7e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KIR60821.1 - 0.0037 17.6 0.9 0.0037 17.6 0.9 2.5 2 1 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.6 KIR60821.1 - 0.008 16.1 0.2 0.031 14.2 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR60821.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh PF00389.30 KIR60821.1 - 3.5 7.3 7.3 63 3.2 7.3 2.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF4381 PF14316.6 KIR60821.1 - 8.6 6.6 9.5 0.87 9.8 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Polyketide_cyc2 PF10604.9 KIR60822.1 - 5e-15 56.0 0.4 5.7e-15 55.8 0.4 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR60822.1 - 5.3e-09 36.4 0.0 7.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 KIR60822.1 - 0.004 17.3 0.2 0.042 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2505) ROK PF00480.20 KIR60823.1 - 1.5e-76 257.7 1.1 1.8e-76 257.5 1.1 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 KIR60823.1 - 0.0061 16.1 2.6 0.012 15.1 0.7 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Succ_CoA_lig PF13607.6 KIR60823.1 - 0.025 14.4 0.2 0.046 13.5 0.2 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain FMO-like PF00743.19 KIR60824.1 - 1.6e-64 218.2 0.0 1.9e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIR60824.1 - 7.2e-21 74.7 0.0 1.9e-16 60.2 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR60824.1 - 4.4e-17 62.2 0.0 5.9e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIR60824.1 - 5e-11 42.3 0.0 3.9e-09 36.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIR60824.1 - 2.5e-08 34.0 0.0 7e-07 29.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR60824.1 - 1.5e-06 28.1 2.5 0.16 11.5 0.3 3.6 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR60824.1 - 0.00017 21.6 2.2 0.1 12.6 0.0 3.9 3 1 0 4 4 4 1 FAD-NAD(P)-binding ThiF PF00899.21 KIR60824.1 - 0.0011 18.4 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 ThiF family Pyr_redox PF00070.27 KIR60824.1 - 0.0017 18.9 2.0 0.53 10.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIR60824.1 - 0.0019 17.5 0.4 0.02 14.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 KIR60824.1 - 0.0019 18.3 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIR60824.1 - 0.0022 17.1 1.8 0.11 11.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KIR60824.1 - 0.0055 16.1 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIR60824.1 - 0.02 13.6 1.2 0.1 11.3 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 KIR60824.1 - 0.023 15.2 0.4 3.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KIR60824.1 - 0.053 12.8 0.2 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 KIR60824.1 - 0.063 12.9 0.3 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KIR60824.1 - 0.11 11.7 0.3 1.2 8.4 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KIR60824.1 - 0.42 9.6 5.0 3.4 6.7 0.4 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Alpha_GJ PF03229.13 KIR60826.1 - 0.74 10.4 4.4 0.82 10.2 4.4 1.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J cNMP_binding PF00027.29 KIR60827.1 - 2.5e-21 75.5 0.0 4.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 KIR60827.1 - 1.7e-16 60.0 0.4 3.1e-16 59.1 0.4 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KIR60827.1 - 0.00026 20.8 0.6 0.001 18.9 0.1 2.3 2 2 1 3 3 3 1 MarR family GntR PF00392.21 KIR60827.1 - 0.0056 16.3 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Phage_rep_O PF04492.13 KIR60827.1 - 0.061 13.9 0.0 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage replication protein O DUF5051 PF16473.5 KIR60828.1 - 3.9e-20 72.5 0.0 5.4e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Pyrid_ox_like PF16242.5 KIR60829.1 - 2.5e-47 160.2 0.0 2.8e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KIR60829.1 - 7.9e-16 58.0 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase P5CR_dimer PF14748.6 KIR60830.1 - 2.4e-38 130.5 0.8 2.4e-38 130.5 0.8 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KIR60830.1 - 2.6e-19 69.6 0.1 7.1e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIR60830.1 - 4.1e-05 23.3 0.1 0.00011 21.9 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KIR60830.1 - 7.5e-05 22.8 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KIR60830.1 - 0.0016 18.6 0.0 0.0069 16.6 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIR60830.1 - 0.0043 16.6 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KIR60830.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIR60830.1 - 0.036 14.9 0.0 0.11 13.4 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KIR60830.1 - 0.045 14.3 1.2 1.2 9.7 0.1 2.9 3 1 0 3 3 3 0 CoA binding domain Sacchrp_dh_NADP PF03435.18 KIR60830.1 - 0.082 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain APH PF01636.23 KIR60831.1 - 2.3e-34 119.4 8.7 3.4e-34 118.8 8.7 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIR60831.1 - 0.0054 15.6 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) AbiEi_4 PF13338.6 KIR60833.1 - 1.1e-06 28.6 0.9 1.1e-06 28.6 0.9 2.3 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin DpnI_C PF17726.1 KIR60833.1 - 0.17 12.0 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 Dam-replacing HTH domain DUF2203 PF09969.9 KIR60834.1 - 4.1e-31 108.2 0.0 4.7e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) PALP PF00291.25 KIR60835.1 - 7.7e-73 245.5 6.7 8.8e-73 245.3 6.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lipase_GDSL_2 PF13472.6 KIR60836.1 - 4e-23 82.7 0.1 4.9e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR60836.1 - 1.7e-09 37.9 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_18 PF00704.28 KIR60837.1 - 2.1e-71 241.2 2.0 2.6e-71 240.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_2 PF00553.19 KIR60837.1 - 3e-23 82.0 7.7 1.2e-22 80.1 7.7 2.1 1 0 0 1 1 1 1 Cellulose binding domain CBM49 PF09478.10 KIR60837.1 - 0.045 14.1 0.1 0.086 13.2 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 DAHP_synth_2 PF01474.16 KIR60838.1 - 3.4e-187 622.3 0.0 4.2e-187 622.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Beta_elim_lyase PF01212.21 KIR60839.1 - 2.7e-81 273.0 0.1 3.4e-81 272.7 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIR60839.1 - 6.8e-05 21.6 0.1 0.0001 21.0 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIR60839.1 - 0.00028 20.2 0.0 0.00034 19.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIR60839.1 - 0.0038 16.6 1.5 0.0089 15.4 0.3 2.2 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 KIR60839.1 - 0.014 14.1 0.1 0.33 9.6 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class-III AP_endonuc_2 PF01261.24 KIR60840.1 - 9.8e-26 90.5 0.8 1.9e-25 89.5 0.2 1.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Pkinase PF00069.25 KIR60841.1 - 2.7e-48 164.6 0.0 3.6e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PASTA PF03793.19 KIR60841.1 - 1.2e-45 153.2 14.2 1.2e-13 50.7 1.3 4.7 4 0 0 4 4 4 4 PASTA domain Pkinase_Tyr PF07714.17 KIR60841.1 - 3.3e-36 124.9 0.0 4.9e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR60841.1 - 1.8e-08 34.7 7.0 5.7e-07 29.7 2.3 3.5 1 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KIR60841.1 - 0.004 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIR60841.1 - 0.0046 15.8 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIR60841.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.6 1 1 0 1 1 1 0 RIO1 family polyprenyl_synt PF00348.17 KIR60842.1 - 6.6e-50 169.6 0.0 9e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_62 PF03664.13 KIR60843.1 - 1.7e-136 453.9 12.5 2.5e-136 453.4 12.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 RicinB_lectin_2 PF14200.6 KIR60843.1 - 9e-34 116.1 18.4 1.1e-20 74.1 6.4 2.8 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR60843.1 - 2.8e-14 53.4 2.6 4.8e-14 52.7 2.6 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PAS_7 PF12860.7 KIR60843.1 - 0.05 13.8 0.0 4.1 7.6 0.0 2.6 1 1 1 2 2 2 0 PAS fold MTHFR PF02219.17 KIR60844.1 - 9.2e-99 330.4 0.0 1e-98 330.2 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ALG11_N PF15924.5 KIR60844.1 - 0.24 11.4 0.0 0.38 10.8 0.0 1.2 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus CDP-OH_P_transf PF01066.21 KIR60845.1 - 4.6e-11 43.3 1.3 4.6e-11 43.3 1.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NAD_binding_8 PF13450.6 KIR60846.1 - 7.2e-13 48.6 1.0 2.6e-12 46.8 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIR60846.1 - 6.2e-12 45.5 0.1 6.2e-12 45.5 0.1 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KIR60846.1 - 1.2e-07 31.7 19.0 1.4e-06 28.1 19.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR60846.1 - 2.1e-07 31.4 0.8 0.00048 20.6 1.5 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR60846.1 - 7.6e-07 28.6 3.4 0.00016 21.0 2.9 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR60846.1 - 1.4e-05 24.0 2.1 0.0012 17.6 2.8 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KIR60846.1 - 0.00065 19.2 0.9 0.00065 19.2 0.9 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR60846.1 - 0.002 17.3 6.3 0.002 17.3 6.3 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KIR60846.1 - 0.017 15.1 1.5 0.036 14.1 0.6 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KIR60846.1 - 0.026 13.8 1.7 0.052 12.8 1.7 1.5 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KIR60846.1 - 0.037 13.6 0.7 0.066 12.8 0.7 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 KIR60846.1 - 0.13 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ApbA PF02558.16 KIR60846.1 - 0.26 10.9 1.5 0.55 9.9 1.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIR60846.1 - 0.35 10.1 0.3 0.53 9.5 0.3 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIR60846.1 - 0.36 9.8 1.4 0.86 8.6 1.4 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KIR60846.1 - 0.54 9.3 4.2 0.76 8.8 4.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIR60846.1 - 0.69 9.8 2.0 1.1 9.1 2.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIR60846.1 - 1.1 8.5 2.8 1.7 7.8 2.8 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_tranf_2_3 PF13641.6 KIR60847.1 - 5.4e-16 59.2 0.3 7.5e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIR60847.1 - 1.6e-14 54.1 0.0 2.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIR60847.1 - 9.6e-08 31.7 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KIR60847.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3291 PF11695.8 KIR60848.1 - 6.6e-05 22.6 0.6 0.00027 20.6 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3291) FMN_bind PF04205.14 KIR60849.1 - 2.3e-10 40.9 0.1 2.3e-10 40.9 0.1 1.6 2 0 0 2 2 2 1 FMN-binding domain Lip_prot_lig_C PF10437.9 KIR60849.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Ferric_reduct PF01794.19 KIR60850.1 - 7.4e-16 58.4 9.6 7.4e-16 58.4 9.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KIR60850.1 - 1.9e-08 34.9 0.0 3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KIR60850.1 - 0.14 12.3 0.0 1.3 9.2 0.0 2.2 1 1 0 1 1 1 0 FAD-binding domain HEPN_SAV_6107 PF18726.1 KIR60851.1 - 1e-34 118.9 14.2 1.6e-34 118.4 14.2 1.3 1 0 0 1 1 1 1 SAV_6107-like HEPN HEPN PF05168.14 KIR60851.1 - 0.064 13.4 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 HEPN domain IMS PF00817.20 KIR60852.1 - 9e-11 42.0 0.1 1.5e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family SPOR PF05036.13 KIR60852.1 - 0.045 14.1 0.1 0.44 11.0 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain DNA_pol3_alpha PF07733.12 KIR60853.1 - 5.7e-76 255.5 0.0 1.1e-75 254.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 KIR60853.1 - 1.2e-54 184.1 0.0 1.8e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 KIR60853.1 - 3.2e-27 95.8 0.0 5.2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 KIR60853.1 - 1.4e-25 89.3 0.0 3.4e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 KIR60853.1 - 9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HHH_3 PF12836.7 KIR60853.1 - 0.00066 19.9 0.0 0.002 18.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_Tnp_1 PF01527.20 KIR60853.1 - 0.43 10.9 4.1 0.59 10.5 0.1 3.0 4 0 0 4 4 4 0 Transposase Methyltransf_25 PF13649.6 KIR60854.1 - 3.7e-17 62.8 0.2 7.3e-17 61.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR60854.1 - 9e-17 61.5 0.5 1.6e-16 60.7 0.2 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR60854.1 - 4.7e-15 56.1 0.0 7.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR60854.1 - 4.5e-14 52.6 0.0 6.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR60854.1 - 1.2e-11 44.6 0.0 1.7e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR60854.1 - 1.3e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KIR60854.1 - 4.6e-06 26.3 0.0 6.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KIR60854.1 - 1.4e-05 24.7 0.1 2.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.16 KIR60854.1 - 2.3e-05 24.2 0.0 3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein NodS PF05401.11 KIR60854.1 - 2.7e-05 23.9 0.1 4.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 KIR60854.1 - 0.01 16.9 1.1 0.024 15.6 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KIR60854.1 - 0.022 14.2 0.7 0.029 13.8 0.7 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 3HCDH_N PF02737.18 KIR60854.1 - 0.032 14.1 0.6 0.042 13.7 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.19 KIR60854.1 - 0.038 13.7 0.2 0.054 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CbiA PF01656.23 KIR60854.1 - 0.079 13.0 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF938 PF06080.12 KIR60854.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.20 KIR60854.1 - 0.28 10.2 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase IMS PF00817.20 KIR60855.1 - 4e-51 173.0 0.0 6.6e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIR60855.1 - 3.3e-23 82.6 0.0 7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KIR60855.1 - 4.1e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 KIR60855.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF3040 PF11239.8 KIR60856.1 - 9.6e-25 86.7 0.3 9.6e-25 86.7 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) DoxX_2 PF13564.6 KIR60856.1 - 0.0042 17.2 1.1 0.0051 16.9 1.1 1.1 1 0 0 1 1 1 1 DoxX-like family MFS_1 PF07690.16 KIR60856.1 - 0.0069 15.4 0.2 0.0077 15.2 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RskA PF10099.9 KIR60856.1 - 0.065 13.5 1.8 0.088 13.1 1.8 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3098 PF11297.8 KIR60856.1 - 3 7.5 4.8 21 4.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3098) DUF397 PF04149.12 KIR60859.1 - 3.2e-21 75.1 0.9 3.5e-21 75.0 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Cohesin_HEAT PF12765.7 KIR60859.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion HTH_31 PF13560.6 KIR60860.1 - 8.6e-16 58.0 1.3 2.8e-15 56.4 1.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR60860.1 - 8.9e-07 28.9 0.2 1.6e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 KIR60860.1 - 9.2e-07 28.6 0.1 3.7e-06 26.7 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR60860.1 - 0.00086 19.3 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 KIR60860.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 KIR60860.1 - 0.032 14.2 1.2 0.07 13.1 0.1 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR60860.1 - 0.049 13.5 0.1 0.18 11.6 0.1 2.0 1 0 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.6 KIR60860.1 - 0.05 14.1 0.2 0.73 10.3 0.0 2.2 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain RWP-RK PF02042.15 KIR60860.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain HTH_psq PF05225.16 KIR60860.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Transglut_core PF01841.19 KIR60861.1 - 2.5e-28 98.8 0.7 2.1e-27 95.8 0.1 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily Transglut_core3 PF13471.6 KIR60861.1 - 0.014 15.3 0.0 0.014 15.3 0.0 3.7 3 1 0 4 4 4 0 Transglutaminase-like superfamily AAA_3 PF07726.11 KIR60862.1 - 4.8e-64 214.1 0.0 8.7e-64 213.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIR60862.1 - 1.3e-22 79.4 6.5 3.2e-22 78.2 6.5 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 KIR60862.1 - 1.4e-14 54.3 0.0 2.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KIR60862.1 - 7.9e-08 31.7 0.0 1.6e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 KIR60862.1 - 1.8e-05 25.2 0.0 7.1e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIR60862.1 - 0.00022 21.0 0.0 0.0066 16.2 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KIR60862.1 - 0.00024 20.9 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIR60862.1 - 0.00097 18.6 0.6 0.66 9.3 0.1 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 KIR60862.1 - 0.07 13.8 0.2 0.29 11.8 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal AAA_18 PF13238.6 KIR60862.1 - 0.071 13.7 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR60862.1 - 0.096 13.1 3.0 2.8 8.3 3.0 2.7 1 1 0 1 1 1 0 AAA ATPase domain tRNA-synt_1_2 PF13603.6 KIR60863.1 - 4.6e-54 182.7 0.0 7.9e-54 182.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 KIR60863.1 - 6.1e-36 123.9 0.0 1.9e-15 56.2 0.0 5.1 3 2 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KIR60863.1 - 2.8e-16 59.3 0.0 7e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KIR60863.1 - 4.8e-16 59.1 0.0 1.7e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KIR60863.1 - 0.091 12.1 0.0 0.73 9.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GATase_3 PF07685.14 KIR60864.1 - 1.4e-33 116.2 0.0 1.6e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KIR60864.1 - 0.0044 16.8 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 KIR60864.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family GATase PF00117.28 KIR60864.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 KIR60864.1 - 0.046 13.4 0.1 0.06 13.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S51 DUF1727 PF08353.10 KIR60865.1 - 3.6e-19 68.7 0.0 1.4e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1727) Mur_ligase_M PF08245.12 KIR60865.1 - 1e-14 55.0 0.0 1.4e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 Mur ligase middle domain PPR_long PF17177.4 KIR60865.1 - 0.12 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP OrfB_Zn_ribbon PF07282.11 KIR60865.1 - 0.15 12.0 0.6 0.3 11.1 0.6 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.12 KIR60865.1 - 0.54 10.3 3.7 0.15 12.0 0.6 1.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon MraZ PF02381.18 KIR60866.1 - 1.7e-39 133.6 0.0 2.2e-19 69.2 0.0 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like DUF932 PF06067.11 KIR60866.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DivIC PF04977.15 KIR60867.1 - 1.3e-05 24.8 0.1 2.7e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Septum formation initiator RskA PF10099.9 KIR60867.1 - 0.0011 19.2 6.9 0.0021 18.4 6.9 1.6 1 1 0 1 1 1 1 Anti-sigma-K factor rskA MscS_porin PF12795.7 KIR60867.1 - 0.0045 16.6 1.9 0.0062 16.1 1.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain SP_C-Propep PF08999.10 KIR60867.1 - 0.054 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF1043 PF06295.12 KIR60867.1 - 0.054 13.5 0.2 0.086 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4381 PF14316.6 KIR60867.1 - 0.055 13.7 0.1 0.093 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 KIR60867.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Transpeptidase PF00905.22 KIR60868.1 - 2.7e-73 246.8 0.0 3.4e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 KIR60868.1 - 5.5e-18 65.9 0.1 1.2e-16 61.6 0.1 2.2 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Beta-lactamase2 PF13354.6 KIR60868.1 - 0.00061 19.5 0.0 0.018 14.6 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase enzyme family Plectin PF00681.20 KIR60868.1 - 0.048 13.6 0.1 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 Plectin repeat Mur_ligase_M PF08245.12 KIR60869.1 - 2.2e-38 132.2 0.0 3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KIR60869.1 - 6.6e-23 80.8 0.8 5.9e-21 74.5 0.0 3.2 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 KIR60869.1 - 1.8e-12 47.4 5.8 3e-12 46.7 0.7 3.5 3 2 0 3 3 3 1 Mur ligase family, catalytic domain ADH_zinc_N PF00107.26 KIR60869.1 - 0.99 9.4 7.1 2.8 7.9 2.1 3.5 2 2 0 2 2 2 0 Zinc-binding dehydrogenase Mur_ligase_M PF08245.12 KIR60870.1 - 2.5e-42 145.1 0.0 3.3e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KIR60870.1 - 1.8e-18 66.6 0.4 8.3e-18 64.4 0.0 2.3 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 KIR60870.1 - 1.5e-11 44.5 0.7 1.6e-10 41.1 0.2 2.7 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Glycos_transf_4 PF00953.21 KIR60871.1 - 1.9e-34 118.9 11.4 1.9e-34 118.9 11.4 2.6 2 1 1 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 KIR60871.1 - 3.1e-06 26.4 4.5 1.3e-05 24.4 4.5 2.2 1 0 0 1 1 1 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Glyco_transf_28 PF03033.20 KIR60872.1 - 2e-35 121.8 0.0 5.6e-34 117.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 KIR60872.1 - 1.2e-33 116.5 0.0 1.6e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 KIR60872.1 - 4.3e-06 26.8 0.3 0.00018 21.6 0.1 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIR60872.1 - 9.5e-05 22.9 18.0 0.00014 22.4 0.5 3.6 1 1 2 3 3 3 2 Glycosyl transferase 4-like domain Mur_ligase_M PF08245.12 KIR60873.1 - 1.2e-25 90.7 0.0 1.6e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 KIR60873.1 - 1.9e-19 69.8 0.1 6.5e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 KIR60873.1 - 3.9e-16 59.1 0.1 9.4e-15 54.6 0.0 2.7 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain POTRA_1 PF08478.10 KIR60874.1 - 4e-15 55.9 0.1 7.1e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 POTRA domain, FtsQ-type FtsQ PF03799.15 KIR60874.1 - 1.7e-07 32.0 0.0 3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ Tubulin PF00091.25 KIR60875.1 - 5.4e-37 127.9 0.3 9.4e-37 127.1 0.3 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KIR60875.1 - 3.6e-36 123.3 1.8 8e-36 122.2 1.8 1.6 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 KIR60875.1 - 0.049 13.5 0.3 0.38 10.6 0.0 2.2 2 1 0 2 2 2 0 NAD(P)H-binding SepF PF04472.12 KIR60876.1 - 1.4e-25 89.4 0.0 1.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Cell division protein SepF YGGT PF02325.17 KIR60877.1 - 6.3e-12 45.7 7.3 8.9e-12 45.3 7.3 1.2 1 0 0 1 1 1 1 YGGT family Sigma_reg_N PF13800.6 KIR60877.1 - 0.47 10.8 4.5 9.7 6.6 1.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DivIVA PF05103.13 KIR60878.1 - 2.6e-18 66.4 20.9 1.5e-11 44.5 0.0 3.6 2 1 1 3 3 3 3 DivIVA protein V-ATPase_G PF03179.15 KIR60878.1 - 0.0085 16.6 10.9 0.0085 16.6 10.9 2.6 3 0 0 3 3 3 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KIR60878.1 - 0.0095 15.4 12.7 0.0095 15.4 12.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3552) RNA_polI_A14 PF08203.11 KIR60878.1 - 0.011 16.4 2.2 0.13 13.0 0.0 2.4 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 ATP-grasp_2 PF08442.10 KIR60878.1 - 0.018 14.6 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain Spc7 PF08317.11 KIR60878.1 - 0.025 13.5 12.8 0.61 8.9 7.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 KIR60878.1 - 0.19 11.1 19.4 0.97 8.7 19.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KIR60878.1 - 0.48 10.7 1.9 11 6.4 0.1 2.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) REF PF05755.12 KIR60878.1 - 0.6 9.9 1.9 0.67 9.7 0.8 1.6 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Borrelia_P83 PF05262.11 KIR60878.1 - 1.7 7.1 14.1 2.2 6.7 14.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HrpE PF06188.12 KIR60878.1 - 2.3 8.0 15.2 1.2 9.0 10.6 2.3 1 1 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E Taxilin PF09728.9 KIR60878.1 - 3 6.9 13.4 3.6 6.7 10.7 2.3 1 1 0 2 2 2 0 Myosin-like coiled-coil protein BRE1 PF08647.11 KIR60878.1 - 5.8 7.0 17.5 2.3 8.4 6.8 3.4 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 KIR60878.1 - 8.9 6.8 22.7 23 5.4 2.4 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 KIR60878.1 - 8.9 7.0 8.4 25 5.6 0.1 3.2 2 1 0 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 KIR60878.1 - 9.5 6.3 25.2 1.9 8.6 2.3 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Ada_Zn_binding PF02805.16 KIR60879.1 - 0.024 14.6 0.3 0.043 13.8 0.3 1.4 1 0 0 1 1 1 0 Metal binding domain of Ada Phage_holin_3_6 PF07332.11 KIR60879.1 - 1.2 9.2 11.9 1.7 8.7 11.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SseC PF04888.12 KIR60879.1 - 7.5 6.1 8.2 10 5.6 8.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF167 PF02594.16 KIR60880.1 - 8.8e-20 70.6 0.1 1e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Na_H_Exchanger PF00999.21 KIR60881.1 - 2.9e-50 171.2 41.3 3.6e-50 170.8 41.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.21 KIR60881.1 - 1.8e-10 40.5 0.4 4e-10 39.4 0.4 1.7 1 0 0 1 1 1 1 TrkA-C domain DUF2374 PF09574.10 KIR60881.1 - 1.7 8.5 6.0 3.7 7.4 3.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) DUF4175 PF13779.6 KIR60881.1 - 2.2 6.1 4.7 4.3 5.1 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_A8 PF01252.18 KIR60882.1 - 2.7e-29 102.2 0.5 3.2e-29 102.0 0.5 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II PseudoU_synth_2 PF00849.22 KIR60883.1 - 5.6e-33 114.3 0.0 1.2e-32 113.2 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KIR60883.1 - 0.00077 19.1 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain AAA_31 PF13614.6 KIR60884.1 - 4.3e-06 26.7 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KIR60884.1 - 0.067 13.3 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2567 PF10821.8 KIR60885.1 - 4.6e-05 23.6 10.7 0.00019 21.5 10.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2567) DUF4131 PF13567.6 KIR60885.1 - 7.3 6.2 10.6 0.59 9.8 4.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) LON_substr_bdg PF02190.16 KIR60886.1 - 4e-29 102.0 0.0 4.9e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Histidinol_dh PF00815.20 KIR60887.1 - 2.9e-156 520.6 1.1 3.3e-156 520.4 1.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Aminotran_1_2 PF00155.21 KIR60888.1 - 7.4e-57 193.2 0.0 8.9e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR60888.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 KIR60888.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Allinase IGPD PF00475.18 KIR60889.1 - 2.7e-58 196.4 0.2 4.1e-58 195.8 0.1 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DS PF01916.17 KIR60889.1 - 0.041 13.1 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Deoxyhypusine synthase GATase PF00117.28 KIR60890.1 - 3.7e-18 66.0 0.0 4.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KIR60890.1 - 4.7e-06 26.4 0.0 6.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KIR60890.1 - 4.8e-05 23.3 0.1 0.00046 20.1 0.1 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family DJ-1_PfpI PF01965.24 KIR60890.1 - 0.0025 17.6 0.9 0.0025 17.6 0.9 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KIR60890.1 - 0.0027 17.5 0.9 0.0098 15.7 0.9 1.9 1 1 0 1 1 1 1 Peptidase C26 Wzy_C PF04932.15 KIR60891.1 - 0.29 10.7 3.9 0.42 10.2 3.9 1.1 1 0 0 1 1 1 0 O-Antigen ligase His_biosynth PF00977.21 KIR60892.1 - 1.3e-63 214.6 0.2 1.4e-63 214.4 0.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 KIR60892.1 - 3e-05 23.3 0.0 0.013 14.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 KIR60892.1 - 4.4e-05 23.0 5.4 0.021 14.2 1.5 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase DHO_dh PF01180.21 KIR60892.1 - 0.012 14.8 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase IMPDH PF00478.25 KIR60892.1 - 0.039 12.9 1.2 4.5 6.2 0.4 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIR60892.1 - 6.7 5.6 9.5 6.5 5.7 1.7 2.4 2 1 1 3 3 3 0 FMN-dependent dehydrogenase Ribonuc_L-PSP PF01042.21 KIR60893.1 - 1.6e-18 66.8 0.2 1.9e-18 66.6 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MarR PF01047.22 KIR60894.1 - 3.9e-13 49.1 0.0 6.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR60894.1 - 1.9e-11 44.3 0.8 3.2e-11 43.5 0.1 1.8 3 0 0 3 3 3 1 Winged helix DNA-binding domain MarR_2 PF12802.7 KIR60894.1 - 7.8e-11 41.7 0.5 1.7e-10 40.7 0.5 1.6 1 0 0 1 1 1 1 MarR family HxlR PF01638.17 KIR60894.1 - 4.3e-05 23.3 0.0 7.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 KIR60894.1 - 4.7e-05 23.3 0.0 7.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KIR60894.1 - 7.3e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 KIR60894.1 - 0.0011 19.0 0.9 0.0014 18.6 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 KIR60894.1 - 0.055 13.1 0.3 0.13 11.9 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family LexA_DNA_bind PF01726.16 KIR60894.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.6 1 1 0 1 1 1 0 LexA DNA binding domain ADH_N_2 PF16884.5 KIR60895.1 - 4.5e-37 126.3 0.0 8.5e-37 125.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIR60895.1 - 2.5e-21 76.0 0.2 3.8e-21 75.4 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR60895.1 - 5.8e-10 40.3 0.3 1.3e-09 39.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase His_biosynth PF00977.21 KIR60896.1 - 1.4e-81 273.4 0.4 1.5e-81 273.2 0.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KIR60896.1 - 4.9e-06 26.2 12.0 0.0066 15.9 0.5 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 KIR60896.1 - 2.9e-05 23.5 6.1 0.017 14.4 0.6 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KIR60896.1 - 0.00013 21.1 3.2 0.019 14.0 0.5 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 KIR60896.1 - 0.00033 20.1 0.4 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 KIR60896.1 - 0.00053 19.2 0.0 0.044 12.9 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KIR60896.1 - 0.00055 19.3 0.8 0.67 9.3 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase DHO_dh PF01180.21 KIR60896.1 - 0.027 13.7 2.4 0.76 8.9 0.0 2.5 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase HemN_C PF06969.16 KIR60897.1 - 0.0059 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 HemN C-terminal domain Aminotran_1_2 PF00155.21 KIR60898.1 - 3.6e-28 98.8 0.0 4.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 KIR60898.1 - 1.8e-12 46.7 0.6 6.9e-12 44.8 0.6 2.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 KIR60898.1 - 5.2e-05 22.2 0.0 7.6e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Rrf2 PF02082.20 KIR60898.1 - 0.0049 17.2 0.1 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 KIR60898.1 - 0.0062 16.1 0.3 0.018 14.6 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KIR60898.1 - 0.0074 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KIR60898.1 - 0.012 15.5 0.7 0.086 12.7 0.6 2.6 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 KIR60898.1 - 0.02 15.0 0.4 0.097 12.8 0.4 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 KIR60898.1 - 0.025 14.5 0.2 0.083 12.9 0.2 1.8 2 0 0 2 2 2 0 HTH domain MarR PF01047.22 KIR60898.1 - 0.086 12.8 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family Paramyxo_NS_C PF02725.14 KIR60898.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Non-structural protein C HTH_AsnC-type PF13404.6 KIR60898.1 - 0.33 10.8 3.5 2.4 8.1 1.3 3.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LtrA PF06772.11 KIR60899.1 - 2.3e-79 267.2 41.5 2.9e-79 266.8 41.5 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) AMP-binding PF00501.28 KIR60900.1 - 1.7e-89 300.4 0.0 2.5e-89 299.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme TRI5 PF06330.11 KIR60901.1 - 0.019 13.9 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) MDMPI_N PF11716.8 KIR60902.1 - 6.4e-05 23.7 9.9 6.4e-05 23.7 9.9 1.9 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 KIR60902.1 - 0.0025 18.6 8.6 0.0025 18.6 8.6 2.5 2 1 1 3 3 3 1 MDMPI C-terminal domain HTH_32 PF13565.6 KIR60902.1 - 0.043 14.4 3.5 6.2 7.5 0.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain ABC_membrane PF00664.23 KIR60903.1 - 6.7e-33 114.5 1.0 8.8e-33 114.1 1.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR60903.1 - 7.1e-28 97.8 0.0 1.2e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR60903.1 - 0.0003 21.2 0.5 0.00078 19.9 0.5 1.7 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIR60903.1 - 0.0021 17.5 0.0 0.0081 15.6 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR60903.1 - 0.0032 17.2 0.1 0.007 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.20 KIR60903.1 - 0.0075 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KIR60903.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KIR60903.1 - 0.023 14.3 1.8 0.22 11.1 1.8 2.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KIR60903.1 - 0.039 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KIR60903.1 - 0.054 13.8 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIR60903.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KIR60903.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KIR60903.1 - 0.13 11.4 0.0 0.98 8.6 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KIR60903.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KIR60903.1 - 0.25 11.8 0.1 0.38 11.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIR60903.1 - 0.28 10.7 0.1 0.47 10.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KIR60904.1 - 6.6e-29 101.2 0.0 1.1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIR60904.1 - 5.4e-28 98.4 7.2 7.3e-28 98.0 7.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF87 PF01935.17 KIR60904.1 - 0.00012 22.2 0.1 0.0003 21.0 0.1 1.6 2 0 0 2 2 2 1 Helicase HerA, central domain SMC_N PF02463.19 KIR60904.1 - 0.00068 19.1 0.0 0.045 13.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR60904.1 - 0.00079 19.7 0.0 0.007 16.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIR60904.1 - 0.021 14.5 0.1 0.043 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR60904.1 - 0.056 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIR60904.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 KIR60904.1 - 0.062 12.6 1.8 0.1 11.8 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin Sigma54_activat PF00158.26 KIR60904.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 KIR60904.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KIR60904.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KIR60904.1 - 0.17 11.7 0.0 7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 KIR60904.1 - 0.18 11.8 0.1 0.35 10.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KIR60904.1 - 0.19 11.5 0.4 1.1 9.0 0.4 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KIR60904.1 - 0.2 11.2 5.4 0.44 10.1 2.3 2.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIR60904.1 - 0.21 12.2 0.0 0.45 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR60904.1 - 0.94 9.8 6.5 0.12 12.8 1.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain TetR_C_16 PF17920.1 KIR60905.1 - 1.5e-36 124.8 4.2 1.5e-36 124.8 4.2 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR60905.1 - 1.4e-17 63.2 2.0 2.4e-17 62.5 2.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 KIR60905.1 - 0.0007 19.9 4.8 0.0007 19.9 4.8 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain ABC2_membrane PF01061.24 KIR60906.1 - 1.2e-34 119.6 11.5 1.8e-34 119.0 11.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR60906.1 - 1.2e-20 73.9 8.8 1.2e-20 73.9 8.8 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KIR60906.1 - 7e-10 38.7 20.9 4.9e-09 35.9 20.9 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR60906.1 - 8.2e-08 32.4 7.5 1.6e-07 31.4 7.5 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein COX6A PF02046.15 KIR60906.1 - 0.29 11.6 0.2 2.8 8.4 0.0 2.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIa Chorismate_bind PF00425.18 KIR60907.1 - 9.1e-98 326.9 0.0 1.1e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KIR60907.1 - 1.3e-30 106.5 0.0 8.7e-29 100.6 0.0 2.3 2 0 0 2 2 2 2 Anthranilate synthase component I, N terminal region Trp_oprn_chp PF09534.10 KIR60908.1 - 1.2e-31 110.0 31.5 1e-30 106.9 31.5 1.9 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_2_1 PF04971.12 KIR60908.1 - 0.059 13.4 1.8 0.15 12.1 1.8 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF1304 PF06993.12 KIR60908.1 - 4.2 7.4 6.7 11 6.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) IGPS PF00218.21 KIR60910.1 - 3.6e-80 268.8 0.0 4.1e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 KIR60910.1 - 3.2e-07 29.7 1.3 7.3e-05 21.9 0.4 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NanE PF04131.14 KIR60910.1 - 0.0002 20.6 0.5 0.0034 16.6 0.2 2.6 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.19 KIR60910.1 - 0.032 14.0 0.1 0.062 13.1 0.0 1.5 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 KIR60910.1 - 0.035 13.7 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 KIR60910.1 - 0.13 11.7 0.9 2.3 7.6 0.1 2.6 1 1 2 3 3 3 0 Histidine biosynthesis protein IMPDH PF00478.25 KIR60910.1 - 0.15 11.0 1.2 0.84 8.6 0.0 2.2 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain PALP PF00291.25 KIR60911.1 - 1.9e-44 152.3 5.6 2.3e-44 152.0 5.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 KIR60912.1 - 7.1e-69 231.5 0.1 7.8e-69 231.4 0.1 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain KDGP_aldolase PF07071.11 KIR60912.1 - 0.0025 17.7 0.7 0.25 11.1 0.1 2.4 2 1 0 2 2 2 2 KDGP aldolase LGT PF01790.18 KIR60913.1 - 6.2e-64 215.5 4.6 7.3e-64 215.3 4.6 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase FAD_binding_3 PF01494.19 KIR60914.1 - 1.7e-19 70.3 4.7 7.5e-09 35.3 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIR60914.1 - 2.9e-07 30.0 0.7 0.0002 20.7 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR60914.1 - 2.7e-06 27.5 2.4 4.2e-06 26.9 0.3 2.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIR60914.1 - 6.7e-06 26.6 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR60914.1 - 4.3e-05 23.3 9.3 0.00011 21.9 1.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIR60914.1 - 0.00047 19.3 0.0 0.00047 19.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 KIR60914.1 - 0.00081 18.5 0.0 0.032 13.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 KIR60914.1 - 0.001 18.2 1.1 0.0025 16.9 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KIR60914.1 - 0.016 14.8 1.3 0.038 13.6 1.3 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KIR60914.1 - 0.018 14.1 0.8 0.027 13.6 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KIR60914.1 - 0.019 13.6 0.4 0.18 10.5 0.5 1.9 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 KIR60914.1 - 0.059 12.6 1.9 0.22 10.8 0.4 2.2 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KIR60914.1 - 0.099 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KIR60914.1 - 0.23 10.3 0.8 12 4.6 0.5 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KIR60914.1 - 0.23 10.6 0.3 0.44 9.7 0.3 1.3 1 0 0 1 1 1 0 Thi4 family FR47 PF08445.10 KIR60915.1 - 7.7e-08 32.2 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIR60915.1 - 3.5e-05 23.7 0.0 8.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR60915.1 - 7.1e-05 22.9 0.1 0.00012 22.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR60915.1 - 0.00027 21.1 0.1 0.00049 20.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR60915.1 - 0.032 14.7 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GATase_2 PF00310.21 KIR60916.1 - 1.3e-170 567.7 0.0 1.8e-170 567.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KIR60916.1 - 5e-150 499.7 0.0 7e-148 492.7 0.0 2.4 3 0 0 3 3 3 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KIR60916.1 - 1.5e-113 378.9 0.0 2.3e-113 378.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 KIR60916.1 - 1.4e-75 253.0 2.2 2.3e-75 252.4 2.2 1.3 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 KIR60916.1 - 0.002 17.2 0.6 0.0046 16.0 0.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase LcnG-beta PF11632.8 KIR60916.1 - 0.0086 16.0 0.3 3.8 7.6 0.1 3.5 4 0 0 4 4 4 1 Lactococcin G-beta Pyr_redox_2 PF07992.14 KIR60917.1 - 5.3e-26 91.5 3.6 1e-25 90.6 3.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KIR60917.1 - 2.1e-23 82.2 0.0 3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KIR60917.1 - 2.2e-09 37.4 0.8 6.4e-09 35.9 0.8 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIR60917.1 - 2.7e-07 30.3 6.4 3e-07 30.1 0.8 2.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIR60917.1 - 2.8e-07 30.1 0.1 0.011 15.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR60917.1 - 3.1e-07 30.9 2.8 0.00039 20.9 0.1 3.1 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR60917.1 - 5.1e-07 29.4 0.5 5.1e-07 29.4 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KIR60917.1 - 1.1e-05 25.2 13.8 2.9e-05 23.8 1.5 2.9 1 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR60917.1 - 1.2e-05 24.2 0.2 2.9e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KIR60917.1 - 3.9e-05 23.1 0.4 8.3e-05 22.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KIR60917.1 - 4.3e-05 23.9 1.9 0.029 14.8 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIR60917.1 - 6.3e-05 22.2 1.8 6.3e-05 22.2 1.8 2.4 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIR60917.1 - 0.00017 20.9 0.1 0.00035 19.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KIR60917.1 - 0.001 18.2 1.3 0.002 17.3 0.8 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 KIR60917.1 - 0.0016 18.3 0.1 0.0027 17.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIR60917.1 - 0.0045 16.3 2.2 0.074 12.3 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KIR60917.1 - 0.018 15.0 8.6 0.21 11.5 0.3 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding FMO-like PF00743.19 KIR60917.1 - 0.024 13.1 0.0 0.069 11.6 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 KIR60917.1 - 0.031 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KIR60917.1 - 0.046 13.4 0.2 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DJ-1_PfpI PF01965.24 KIR60917.1 - 0.065 13.0 2.9 0.1 12.4 0.0 2.5 3 0 0 3 3 3 0 DJ-1/PfpI family NAD_binding_2 PF03446.15 KIR60917.1 - 0.084 13.0 0.1 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase K_oxygenase PF13434.6 KIR60917.1 - 0.097 11.8 1.1 2.7 7.1 0.0 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KIR60917.1 - 0.14 11.2 4.6 0.065 12.3 0.4 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KIR60917.1 - 0.33 9.8 2.3 0.57 9.0 0.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AdoHcyase_NAD PF00670.21 KIR60917.1 - 0.35 10.9 1.2 28 4.8 0.1 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain YjeF_N PF03853.15 KIR60917.1 - 0.48 10.3 5.1 1 9.2 1.0 2.6 1 1 1 2 2 2 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 KIR60917.1 - 1.3 9.6 4.0 1.7 9.3 0.1 3.0 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent Fer4_4 PF12800.7 KIR60917.1 - 6.2 7.6 8.7 0.58 10.8 1.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_M1 PF01433.20 KIR60918.1 - 1.3e-25 90.3 1.3 2.2e-25 89.5 1.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIR60918.1 - 4e-09 36.9 0.0 7.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DNA_pol3_gamma3 PF12169.8 KIR60918.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Lipase_GDSL_2 PF13472.6 KIR60919.1 - 1.5e-24 87.4 0.4 2.1e-24 86.9 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR60919.1 - 6.6e-07 29.5 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FtsK_SpoIIIE PF01580.18 KIR60920.1 - 2.7e-22 79.3 0.0 8.7e-21 74.4 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family TraG-D_C PF12696.7 KIR60920.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 KIR60920.1 - 2.4e-05 23.5 0.0 0.0037 16.2 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KIR60920.1 - 0.0028 17.9 0.0 0.0082 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 KIR60920.1 - 0.0097 14.9 0.0 0.7 8.7 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain DUF853 PF05872.12 KIR60920.1 - 0.022 13.4 0.0 0.73 8.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 KIR60920.1 - 0.069 13.2 0.3 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KIR60920.1 - 0.24 10.6 0.1 45 3.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin zf-HC2 PF13490.6 KIR60920.1 - 0.3 11.4 2.4 0.39 11.0 0.1 2.5 2 0 0 2 2 2 0 Putative zinc-finger DUF2075 PF09848.9 KIR60920.1 - 0.31 10.2 0.0 2.2 7.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Herpes_UL25 PF01499.16 KIR60921.1 - 0.11 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2721 PF11026.8 KIR60921.1 - 1.3 8.9 9.5 0.93 9.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PSK_trans_fac PF07704.11 KIR60921.1 - 4.2 8.2 11.1 1.4 9.7 5.8 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor DAO PF01266.24 KIR60922.1 - 1.7e-39 136.5 18.6 3e-39 135.6 18.6 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR60922.1 - 3e-06 26.6 0.6 5.6e-06 25.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIR60922.1 - 3e-05 24.5 0.6 5.8e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR60922.1 - 7.7e-05 22.8 1.3 0.00022 21.4 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIR60922.1 - 0.00015 21.1 1.2 0.00022 20.6 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 KIR60922.1 - 0.00059 20.2 1.8 0.0077 16.7 0.2 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIR60922.1 - 0.00065 19.0 0.9 0.0013 18.0 0.9 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR60922.1 - 0.0045 16.1 0.1 0.0061 15.7 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KIR60922.1 - 0.0089 15.3 0.8 0.018 14.3 0.8 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KIR60922.1 - 0.0095 15.3 2.7 0.018 14.3 2.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIR60922.1 - 0.011 14.5 1.0 0.016 14.0 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KIR60922.1 - 0.027 13.8 4.2 0.047 13.0 4.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIR60922.1 - 0.029 13.4 2.4 0.074 12.1 0.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KIR60922.1 - 0.088 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KIR60922.1 - 0.089 12.0 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIR60922.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KIR60922.1 - 0.16 10.8 0.7 0.22 10.3 0.7 1.1 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 KIR60922.1 - 0.28 11.0 0.5 0.44 10.4 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LysR_substrate PF03466.20 KIR60923.1 - 1.2e-30 106.5 10.8 1.2e-30 106.5 10.8 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 KIR60923.1 - 1.6e-23 82.4 2.3 3.4e-23 81.3 2.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 KIR60923.1 - 0.022 14.5 0.2 0.056 13.2 0.2 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain EcoEI_R_C PF08463.10 KIR60925.1 - 7.7e-40 136.8 0.3 1.2e-38 132.8 0.0 2.9 4 0 0 4 4 4 1 EcoEI R protein C-terminal ResIII PF04851.15 KIR60925.1 - 3e-34 118.5 0.0 4.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KIR60925.1 - 5e-21 75.4 0.0 9.2e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 KIR60925.1 - 7e-06 26.1 0.0 0.00064 19.7 0.0 2.5 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Helicase_C PF00271.31 KIR60925.1 - 8.8e-06 26.0 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4145 PF13643.6 KIR60925.1 - 4.4e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) DEAD PF00270.29 KIR60925.1 - 9e-05 22.3 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase LcrG PF07216.12 KIR60925.1 - 0.063 13.2 2.4 0.25 11.3 2.4 2.0 1 0 0 1 1 1 0 LcrG protein N6_Mtase PF02384.16 KIR60926.1 - 2.3e-63 214.3 0.0 3.4e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 KIR60926.1 - 4.8e-15 56.4 0.1 1.5e-14 54.8 0.1 1.9 1 1 0 1 1 1 1 HsdM N-terminal domain UPF0020 PF01170.18 KIR60926.1 - 1.1e-05 25.2 0.6 0.00011 21.9 0.6 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 RGS12_us2 PF16611.5 KIR60926.1 - 0.00048 20.5 0.0 0.0009 19.6 0.0 1.3 1 0 0 1 1 1 1 Unstructured region between RBD and GoLoco DinB_2 PF12867.7 KIR60927.1 - 1.3 9.5 6.9 8.6 6.9 0.1 3.5 1 1 2 3 3 3 0 DinB superfamily Methyltransf_19 PF04672.12 KIR60928.1 - 3.2e-77 259.6 0.6 3.8e-77 259.4 0.6 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_31 PF13847.6 KIR60928.1 - 0.094 12.5 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain HTH_17 PF12728.7 KIR60929.1 - 0.0053 16.9 0.3 0.023 14.9 0.3 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR60929.1 - 0.023 14.5 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 KIR60929.1 - 0.025 14.7 0.3 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR60929.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_AlpA PF05930.12 KIR60929.1 - 0.076 12.9 2.2 0.15 11.9 2.2 1.5 1 1 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Lipase_2 PF01674.18 KIR60932.1 - 1.8e-09 37.5 0.0 5.5e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 KIR60932.1 - 3.8e-07 30.2 0.0 4.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KIR60932.1 - 1.3e-06 28.3 0.2 1.7e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR60932.1 - 0.00019 22.1 9.9 0.00019 22.1 9.9 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KIR60932.1 - 0.00031 20.3 0.0 0.00063 19.3 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KIR60932.1 - 0.00061 19.1 0.3 0.0013 18.0 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIR60932.1 - 0.001 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KIR60932.1 - 0.0023 17.2 0.0 0.0031 16.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KIR60932.1 - 0.06 12.9 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RskA PF10099.9 KIR60932.1 - 0.19 12.0 11.9 0.043 14.1 8.6 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Aldo_ket_red PF00248.21 KIR60933.1 - 1.8e-61 207.9 0.0 8.6e-46 156.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family GMC_oxred_N PF00732.19 KIR60934.1 - 1.1e-67 228.5 0.0 1.5e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIR60934.1 - 4e-31 108.5 0.1 6.8e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIR60934.1 - 2.6e-08 33.4 1.3 0.0024 17.0 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIR60934.1 - 2.6e-06 27.3 2.1 0.0013 18.4 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIR60934.1 - 1e-05 24.8 0.1 2.1e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIR60934.1 - 0.00028 21.0 5.1 0.00067 19.8 0.4 3.9 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR60934.1 - 0.00045 19.6 0.0 0.0078 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR60934.1 - 0.042 12.6 0.3 0.098 11.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Herpes_LP PF03363.13 KIR60934.1 - 0.048 13.4 1.3 0.25 11.1 0.3 2.3 2 0 0 2 2 2 0 Herpesvirus leader protein ApbA PF02558.16 KIR60934.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 KIR60934.1 - 0.077 12.2 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIR60934.1 - 0.1 11.8 0.0 3 7.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PK PF00224.21 KIR60935.1 - 1.8e-121 405.3 0.4 2.3e-121 404.9 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KIR60935.1 - 9.5e-26 90.3 0.0 1.3e-24 86.7 0.0 2.8 3 1 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KIR60935.1 - 1.7e-06 27.4 1.4 0.00021 20.5 0.3 3.1 3 0 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family HupF_HypC PF01455.18 KIR60935.1 - 0.02 15.0 0.8 2.6 8.3 0.0 3.2 3 0 0 3 3 3 0 HupF/HypC family 4HBT_3 PF13622.6 KIR60936.1 - 2.1e-63 214.9 2.7 2.5e-63 214.7 2.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KIR60936.1 - 1.4e-43 147.9 0.0 8.7e-34 116.2 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase SBP_bac_11 PF13531.6 KIR60937.1 - 1.1e-30 107.1 5.5 1.9e-30 106.4 5.5 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein VWA PF00092.28 KIR60937.1 - 8.6e-12 45.6 0.0 1.6e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIR60937.1 - 5.1e-11 43.2 0.0 2e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIR60937.1 - 2e-06 27.8 0.0 6.3e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain SBP_bac_8 PF13416.6 KIR60937.1 - 0.00031 20.6 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein VWA_CoxE PF05762.14 KIR60937.1 - 0.06 12.7 0.0 0.81 9.0 0.0 2.3 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Rrf2 PF02082.20 KIR60938.1 - 3e-25 88.4 0.0 6.1e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 KIR60938.1 - 0.0021 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Pyridoxal_deC PF00282.19 KIR60939.1 - 2.7e-105 352.2 0.0 3.2e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 KIR60939.1 - 2.2e-06 26.6 0.0 3.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 KIR60939.1 - 2.9e-05 23.2 0.0 4.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIR60939.1 - 7e-05 22.2 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KIR60939.1 - 0.0012 18.2 0.4 0.0018 17.7 0.4 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIR60939.1 - 0.0074 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RGI_lyase PF18370.1 KIR60940.1 - 3.6e-29 100.9 0.0 1.2e-28 99.2 0.0 2.0 1 0 0 1 1 1 1 Rhamnogalacturonan I lyases beta-sheet domain CBM_2 PF00553.19 KIR60940.1 - 2e-28 98.6 11.2 2e-28 98.6 11.2 3.5 3 0 0 3 3 3 1 Cellulose binding domain FG-GAP PF01839.23 KIR60940.1 - 1.6e-09 37.7 19.2 0.0011 19.0 2.8 4.5 3 1 1 4 4 4 3 FG-GAP repeat VCBS PF13517.6 KIR60940.1 - 4.7e-05 23.9 25.4 0.044 14.4 0.5 6.0 5 2 1 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 KIR60940.1 - 0.0017 18.2 0.2 0.44 10.6 0.0 4.0 2 0 0 2 2 2 1 PQQ enzyme repeat Bac_luciferase PF00296.20 KIR60941.1 - 5.5e-37 127.9 13.0 1.2e-36 126.8 13.0 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 KIR60942.1 - 5.1e-46 157.2 58.7 5.1e-46 157.2 58.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PMT_4TMC PF16192.5 KIR60942.1 - 4.1 6.9 5.8 0.42 10.2 1.0 1.7 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase AsnC_trans_reg PF01037.21 KIR60943.1 - 2.2e-15 56.4 0.2 3.6e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 KIR60943.1 - 8.1e-15 54.4 1.8 1.4e-14 53.6 1.8 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR60943.1 - 1.7e-13 49.9 0.1 2.4e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KIR60943.1 - 0.00095 19.2 0.3 0.0023 18.0 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Cys_Met_Meta_PP PF01053.20 KIR60944.1 - 1.3e-94 316.9 0.0 1.5e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIR60944.1 - 0.00031 20.2 2.9 0.00068 19.0 2.9 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_23 PF13384.6 KIR60945.1 - 7.5e-05 22.4 0.3 0.00015 21.5 0.3 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KIR60945.1 - 0.00037 20.4 0.3 0.001 19.1 0.3 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KIR60945.1 - 0.00059 19.9 0.4 0.0015 18.6 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 KIR60945.1 - 0.00065 19.5 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) LAGLIDADG_3 PF14528.6 KIR60945.1 - 0.004 17.4 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 2 LAGLIDADG-like domain Sigma70_r4_2 PF08281.12 KIR60945.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1804 PF08822.11 KIR60945.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_3 PF01381.22 KIR60945.1 - 0.03 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_8 PF02954.19 KIR60945.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_Tnp_1 PF01527.20 KIR60945.1 - 0.05 13.9 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase MerR_1 PF13411.6 KIR60945.1 - 0.15 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Response_reg PF00072.24 KIR60946.1 - 1.2e-28 99.5 0.2 2.3e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain ANTAR PF03861.14 KIR60946.1 - 2.2e-21 75.5 1.7 8.4e-21 73.6 0.2 2.5 2 0 0 2 2 2 1 ANTAR domain 3HCDH_RFF PF18321.1 KIR60946.1 - 0.023 15.1 0.3 0.23 11.9 0.1 2.5 1 1 1 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Peripla_BP_6 PF13458.6 KIR60947.1 - 6.4e-49 167.4 11.4 7.4e-49 167.2 11.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KIR60947.1 - 1.5e-17 63.8 0.0 1.9e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KIR60947.1 - 2e-05 23.8 0.0 3.2e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein domain BPD_transp_2 PF02653.16 KIR60948.1 - 3.7e-42 144.4 35.9 4.4e-42 144.1 35.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DAP10 PF07213.11 KIR60948.1 - 0.18 11.8 0.3 0.18 11.8 0.3 2.4 3 0 0 3 3 3 0 DAP10 membrane protein DUF1576 PF07613.11 KIR60948.1 - 1.4 8.4 14.8 0.048 13.2 6.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1576) Sid-5 PF17204.3 KIR60948.1 - 3.3 8.0 4.6 34 4.7 0.1 3.5 2 1 1 3 3 3 0 Sid-5 family BPD_transp_2 PF02653.16 KIR60949.1 - 1.1e-50 172.2 25.3 1.1e-50 172.2 25.3 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component SP24 PF16504.5 KIR60949.1 - 8.2 6.5 7.0 0.49 10.4 0.2 2.4 3 0 0 3 3 3 0 Putative virion membrane protein of plant and insect virus ABC_tran PF00005.27 KIR60950.1 - 1.1e-33 116.6 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 KIR60950.1 - 7.6e-12 44.9 0.3 1.6e-11 43.9 0.3 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 KIR60950.1 - 2.2e-08 34.3 0.3 0.0045 16.8 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR60950.1 - 0.0012 19.4 0.2 0.0021 18.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR60950.1 - 0.0022 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR60950.1 - 0.056 13.7 1.0 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIR60950.1 - 0.082 12.6 0.3 0.29 10.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIR60950.1 - 0.083 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR60950.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 KIR60950.1 - 0.092 12.2 0.0 0.26 10.7 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 KIR60951.1 - 6.1e-29 101.3 0.0 9.8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR60951.1 - 5.4e-14 52.7 0.2 8.5e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 KIR60951.1 - 6.5e-05 22.7 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_30 PF13604.6 KIR60951.1 - 8.1e-05 22.4 3.4 0.0003 20.6 3.4 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIR60951.1 - 0.0011 18.7 0.1 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 KIR60951.1 - 0.0017 18.9 0.3 0.0075 16.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIR60951.1 - 0.002 17.6 0.3 0.39 10.1 0.2 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR60951.1 - 0.0028 18.0 0.2 0.33 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KIR60951.1 - 0.0029 17.2 0.2 0.013 15.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR60951.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KIR60951.1 - 0.011 15.9 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 KIR60951.1 - 0.016 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 MukB N-terminal SRP54 PF00448.22 KIR60951.1 - 0.016 14.8 0.9 0.021 14.4 0.2 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KIR60951.1 - 0.017 15.3 0.2 0.72 10.1 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KIR60951.1 - 0.018 14.8 0.4 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KIR60951.1 - 0.031 13.9 0.5 0.09 12.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KIR60951.1 - 0.031 13.2 0.2 0.054 12.4 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 KIR60951.1 - 0.068 13.3 0.2 0.096 12.8 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KIR60951.1 - 0.079 13.3 0.8 0.2 12.0 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 KIR60951.1 - 0.081 10.4 0.4 0.12 9.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TsaE PF02367.17 KIR60951.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KIR60951.1 - 0.14 12.5 2.1 0.84 10.0 2.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR60951.1 - 0.14 12.3 0.4 0.45 10.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KIR60951.1 - 0.28 9.8 0.1 0.57 8.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain DNA_pol_A PF00476.20 KIR60953.1 - 1.2e-143 478.7 0.0 1.6e-143 478.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 KIR60953.1 - 2.4e-56 190.0 0.1 4.1e-56 189.3 0.1 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KIR60953.1 - 2.2e-22 79.5 0.0 5.2e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 KIR60953.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HHH_5 PF14520.6 KIR60953.1 - 0.009 16.6 0.3 0.064 13.9 0.0 2.5 2 1 1 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KIR60953.1 - 0.011 15.6 0.1 0.052 13.4 0.0 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH PF00633.23 KIR60953.1 - 0.12 12.2 0.5 0.41 10.6 0.2 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3140 PF11338.8 KIR60954.1 - 1.5e-38 131.1 0.2 1.7e-38 130.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 KIR60955.1 - 1e-20 73.7 0.3 1.1e-20 73.5 0.3 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain S1 PF00575.23 KIR60956.1 - 3.6e-77 254.7 29.8 5.8e-26 90.6 2.8 4.1 4 0 0 4 4 4 4 S1 RNA binding domain DUF2110 PF09883.9 KIR60956.1 - 1.3e-05 24.9 2.5 0.29 10.7 0.1 3.3 3 0 0 3 3 3 3 Uncharacterized protein conserved in archaea (DUF2110) S1_2 PF13509.6 KIR60956.1 - 9.7e-05 22.4 4.0 1 9.5 0.0 4.5 3 2 0 3 3 3 2 S1 domain RNase_II_C_S1 PF18614.1 KIR60956.1 - 0.01 15.7 8.5 0.41 10.6 0.4 3.8 4 0 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain Opi1 PF08618.10 KIR60956.1 - 0.035 13.4 1.3 0.068 12.4 1.3 1.4 1 0 0 1 1 1 0 Transcription factor Opi1 RsgI_N PF12791.7 KIR60956.1 - 0.063 13.2 0.2 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Anti-sigma factor N-terminus DUF2187 PF09953.9 KIR60956.1 - 0.081 12.9 0.4 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) CoaE PF01121.20 KIR60957.1 - 1.1e-53 181.6 0.2 1.4e-53 181.2 0.2 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase GrpB PF04229.14 KIR60957.1 - 2.7e-37 128.4 0.0 4.2e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 GrpB protein AAA_28 PF13521.6 KIR60957.1 - 3.8e-05 24.0 0.9 0.0002 21.6 0.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR60957.1 - 4.7e-05 23.6 0.7 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIR60957.1 - 0.031 14.8 0.0 0.18 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain UvrB_inter PF17757.1 KIR60958.1 - 2.4e-34 117.4 0.1 1.3e-33 115.0 0.0 2.1 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 KIR60958.1 - 3.2e-21 74.9 0.5 7e-21 73.8 0.5 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 KIR60958.1 - 5.2e-18 65.4 0.1 1.1e-17 64.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR60958.1 - 6.3e-09 36.1 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UVR PF02151.19 KIR60958.1 - 1.4e-07 31.0 7.0 6e-07 29.0 7.0 2.2 1 0 0 1 1 1 1 UvrB/uvrC motif AAA_30 PF13604.6 KIR60958.1 - 0.00061 19.6 0.0 0.023 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIR60958.1 - 0.0017 18.8 1.0 0.016 15.6 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain UB2H PF14814.6 KIR60958.1 - 0.0042 17.1 0.0 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain DEAD PF00270.29 KIR60958.1 - 0.0043 16.9 0.0 0.093 12.5 0.0 3.1 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIR60958.1 - 0.0071 16.6 1.5 0.025 14.9 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KIR60958.1 - 0.014 15.8 0.1 2.4 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIR60958.1 - 0.018 15.1 0.2 0.088 12.9 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Helicase_RecD PF05127.14 KIR60958.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.14 KIR60958.1 - 0.1 12.6 0.1 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) adh_short_C2 PF13561.6 KIR60959.1 - 9.3e-39 133.4 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR60959.1 - 1.3e-28 99.8 0.0 2.9e-28 98.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR60959.1 - 9.3e-08 32.2 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 KR domain TerC PF03741.16 KIR60960.1 - 3.6e-56 189.7 5.4 3.6e-56 189.7 5.4 1.8 3 0 0 3 3 3 1 Integral membrane protein TerC family COX14 PF14880.6 KIR60960.1 - 0.094 12.6 0.3 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4381 PF14316.6 KIR60960.1 - 0.15 12.3 0.1 0.58 10.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2244 PF10003.9 KIR60960.1 - 6.2 6.5 7.5 11 5.7 0.9 3.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) MR_MLE_C PF13378.6 KIR60961.1 - 2.4e-52 177.7 4.2 2.4e-52 177.7 4.2 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR60961.1 - 8.9e-20 71.1 0.3 2.4e-19 69.7 0.3 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KIR60961.1 - 0.00017 20.8 0.1 0.0003 20.0 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Y_phosphatase3 PF13350.6 KIR60962.1 - 6.2e-62 209.6 0.0 7e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIR60962.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIR60962.1 - 0.18 11.3 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Beta-lactamase2 PF13354.6 KIR60963.1 - 9.5e-41 139.6 0.0 1.3e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KIR60963.1 - 2.5e-06 26.9 1.9 0.00091 18.6 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase GTP_EFTU PF00009.27 KIR60964.1 - 8.7e-53 178.8 0.0 1.3e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIR60964.1 - 3.5e-22 78.2 0.0 8.3e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIR60964.1 - 3.7e-11 43.3 0.1 1e-10 41.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIR60964.1 - 7e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MarR PF01047.22 KIR60965.1 - 1.1e-10 41.3 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR60965.1 - 5.6e-10 39.0 0.6 1.1e-09 38.0 0.6 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR60965.1 - 4.2e-05 24.0 0.1 7.7e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 KIR60965.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 KIR60965.1 - 0.0026 17.9 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain DUF4423 PF14394.6 KIR60965.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) TrmB PF01978.19 KIR60965.1 - 0.038 13.9 0.0 0.09 12.7 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 KIR60965.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain PAX PF00292.18 KIR60965.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 'Paired box' domain CSD PF00313.22 KIR60966.1 - 4.2e-32 109.8 0.4 4.5e-32 109.7 0.4 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KIR60966.1 - 0.00012 21.7 0.8 0.00014 21.5 0.8 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 KIR60966.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 S1 RNA binding domain CusF_Ec PF11604.8 KIR60966.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF PrmA PF06325.13 KIR60967.1 - 1.5e-11 44.2 2.6 2e-11 43.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIR60967.1 - 6.4e-08 32.3 0.3 9.3e-08 31.8 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KIR60967.1 - 9.9e-07 28.7 0.1 1.3e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KIR60967.1 - 2.9e-06 27.1 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIR60967.1 - 1.1e-05 26.0 0.3 1.8e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 KIR60967.1 - 0.00014 21.2 0.1 0.00018 20.8 0.1 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.15 KIR60967.1 - 0.00082 19.1 0.1 0.0013 18.4 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KIR60967.1 - 0.00083 20.0 0.2 0.0014 19.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIR60967.1 - 0.0084 15.4 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KIR60967.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.17 KIR60967.1 - 0.049 13.0 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_31 PF13847.6 KIR60967.1 - 0.052 13.3 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.11 KIR60968.1 - 6.5e-16 58.9 7.7 6.5e-16 58.9 7.7 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF443 PF04276.12 KIR60968.1 - 0.025 14.4 0.3 0.047 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF443) LapA_dom PF06305.11 KIR60968.1 - 0.31 10.9 8.6 2.5 8.0 1.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Lactamase_B PF00753.27 KIR60969.1 - 5.7e-13 49.3 6.8 9.5e-13 48.6 6.8 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR60969.1 - 0.026 14.0 1.2 0.049 13.2 1.2 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MDMPI_N PF11716.8 KIR60970.1 - 5.4e-28 98.5 24.1 5.4e-28 98.5 24.1 2.0 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DUF664 PF04978.12 KIR60970.1 - 1.1e-07 32.4 3.5 1.6e-07 31.9 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF664) MDMPI_C PF07398.11 KIR60970.1 - 4.5e-06 27.4 8.9 4.5e-06 27.4 8.9 2.9 1 1 2 3 3 3 1 MDMPI C-terminal domain DinB_2 PF12867.7 KIR60970.1 - 2e-05 25.1 7.5 2.3e-05 24.9 6.8 1.4 1 1 0 1 1 1 1 DinB superfamily RsgA_GTPase PF03193.16 KIR60971.1 - 1.6e-40 138.8 0.0 2e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KIR60971.1 - 2e-06 28.4 0.0 3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KIR60971.1 - 2.2e-05 24.5 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KIR60971.1 - 0.00043 20.0 0.0 0.0009 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR60971.1 - 0.00054 20.4 0.5 0.0019 18.6 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 KIR60971.1 - 0.0015 18.6 0.2 0.0048 17.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 KIR60971.1 - 0.0052 16.3 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B IstB_IS21 PF01695.17 KIR60971.1 - 0.042 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 KIR60971.1 - 0.095 13.2 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 KIR60971.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain DUF815 PF05673.13 KIR60971.1 - 0.27 10.4 0.1 0.44 9.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UvrA_inter PF17760.1 KIR60972.1 - 3.5e-38 130.0 0.0 7.7e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 KIR60972.1 - 1.4e-36 125.2 0.0 1.6e-34 118.6 0.0 3.2 3 0 0 3 3 3 1 UvrA DNA-binding domain ABC_tran PF00005.27 KIR60972.1 - 2.5e-20 73.4 0.0 5.5e-11 43.1 0.0 4.2 3 1 0 3 3 3 3 ABC transporter AAA_16 PF13191.6 KIR60972.1 - 5.7e-09 36.6 0.2 0.0018 18.7 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIR60972.1 - 1.7e-07 30.9 0.0 0.0027 17.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR60972.1 - 8.3e-07 29.1 0.1 0.0034 17.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 KIR60972.1 - 1e-06 28.4 0.0 2.1 7.7 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIR60972.1 - 8.8e-06 25.7 0.5 0.29 10.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR60972.1 - 1.5e-05 25.6 0.0 0.26 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIR60972.1 - 1.6e-05 24.5 0.0 0.066 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIR60972.1 - 5.2e-05 23.4 0.0 0.93 9.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain APS_kinase PF01583.20 KIR60972.1 - 0.00014 21.8 0.1 0.52 10.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_22 PF13401.6 KIR60972.1 - 0.00037 20.8 0.0 0.13 12.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KIR60972.1 - 0.00079 20.0 0.0 0.53 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIR60972.1 - 0.0012 18.7 0.1 0.078 12.9 0.0 2.8 3 0 0 3 3 3 1 NACHT domain T2SSE PF00437.20 KIR60972.1 - 0.0063 15.6 0.0 0.25 10.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIR60972.1 - 0.011 15.8 0.2 0.39 10.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KIR60972.1 - 0.015 14.9 0.2 0.43 10.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KIR60972.1 - 0.021 14.0 0.0 0.81 8.8 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain Viral_helicase1 PF01443.18 KIR60972.1 - 0.024 14.4 0.2 0.16 11.7 0.1 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIR60972.1 - 0.037 14.4 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF3667 PF12412.8 KIR60972.1 - 0.04 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) DnaJ_CXXCXGXG PF00684.19 KIR60972.1 - 0.045 14.1 6.6 0.18 12.2 0.2 3.4 4 0 0 4 4 3 0 DnaJ central domain MeaB PF03308.16 KIR60972.1 - 0.045 12.7 0.0 0.39 9.6 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 KIR60972.1 - 0.047 13.4 1.2 0.69 9.6 0.0 2.4 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.9 KIR60972.1 - 0.054 12.7 0.1 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KIR60972.1 - 0.064 12.6 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 KIR60972.1 - 0.071 13.4 0.0 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIR60972.1 - 0.074 13.0 0.3 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KIR60972.1 - 0.088 12.8 0.0 2.8 8.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KIR60972.1 - 0.22 11.2 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KIR60972.1 - 0.27 10.1 1.2 0.42 9.5 0.1 1.7 2 0 0 2 2 2 0 YcjX-like family, DUF463 Zn-ribbon_8 PF09723.10 KIR60972.1 - 0.81 9.9 6.8 16 5.7 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain DUF87 PF01935.17 KIR60972.1 - 2.1 8.4 4.6 0.41 10.7 0.1 2.1 3 0 0 3 3 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 KIR60972.1 - 2.9 7.9 4.3 0.66 10.0 0.1 2.0 2 0 0 2 2 2 0 Dynamin family Anti-TRAP PF15777.5 KIR60972.1 - 3.7 7.6 6.9 14 5.7 0.6 3.7 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Rieske PF00355.26 KIR60973.1 - 2e-12 46.9 0.0 3.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 KIR60973.1 - 0.017 14.9 5.5 0.017 14.9 5.5 2.9 2 1 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Penicil_amidase PF01804.18 KIR60974.1 - 7.9e-112 375.4 10.3 1.3e-111 374.8 10.3 1.3 1 0 0 1 1 1 1 Penicillin amidase F5_F8_type_C PF00754.25 KIR60974.1 - 6e-24 84.6 2.0 1.2e-23 83.6 2.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain UvrC_HhH_N PF08459.11 KIR60975.1 - 2.4e-50 170.5 0.0 6.3e-50 169.1 0.0 1.7 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 KIR60975.1 - 5e-12 46.2 0.1 1.3e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain GIY-YIG PF01541.24 KIR60975.1 - 5.7e-11 42.5 0.0 1.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 KIR60975.1 - 2e-10 40.0 4.8 4.3e-10 39.0 4.8 1.6 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_2 PF12826.7 KIR60975.1 - 1.2e-09 38.1 0.0 3.9e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KIR60975.1 - 1.2e-08 34.4 0.4 1.6e-06 27.6 0.2 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 KIR60975.1 - 0.0018 18.5 0.0 0.22 11.9 0.0 3.0 2 0 0 2 2 2 1 IMS family HHH motif HHH_8 PF14716.6 KIR60975.1 - 0.046 14.1 0.3 0.41 11.0 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_3 PF12836.7 KIR60975.1 - 0.07 13.4 0.0 0.81 10.0 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KIR60975.1 - 0.19 12.3 0.4 5.8 7.6 0.0 3.0 3 1 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Peptidase_S8 PF00082.22 KIR60976.1 - 1.3e-31 109.9 11.2 1.3e-31 109.9 11.2 2.0 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 KIR60976.1 - 3.1e-30 104.0 0.1 6.3e-17 61.4 0.0 2.7 3 0 0 3 3 3 2 Proprotein convertase P-domain Inhibitor_I9 PF05922.16 KIR60976.1 - 0.00024 21.7 0.0 0.00046 20.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 MG2 PF01835.19 KIR60976.1 - 0.0093 16.4 0.3 11 6.5 0.0 3.6 3 0 0 3 3 3 1 MG2 domain CelD_N PF02927.14 KIR60976.1 - 0.034 15.0 0.1 3.7 8.5 0.0 3.3 3 0 0 3 3 3 0 Cellulase N-terminal ig-like domain PPC PF04151.15 KIR60976.1 - 0.32 12.1 11.0 2.2 9.4 3.5 4.3 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain DUF397 PF04149.12 KIR60978.1 - 1.4e-21 76.2 1.2 1.6e-21 76.1 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) SWIM PF04434.17 KIR60979.1 - 0.00023 20.7 0.3 0.00042 19.9 0.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF373 PF04123.13 KIR60980.1 - 0.0043 16.6 2.0 0.0043 16.6 2.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF373) DUF3262 PF11660.8 KIR60980.1 - 0.93 9.9 9.0 0.077 13.4 2.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) CPP1-like PF11833.8 KIR60980.1 - 3.9 7.1 9.0 1.8 8.1 1.4 2.9 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like EptA_B_N PF08019.12 KIR60980.1 - 9.2 6.1 11.7 0.25 11.2 3.6 2.5 2 1 1 3 3 3 0 Phosphoethanolamine transferase EptA/EptB WhiA_N PF10298.9 KIR60981.1 - 3.3e-28 97.6 0.0 9.9e-28 96.0 0.0 1.9 1 0 0 1 1 1 1 WhiA N-terminal LAGLIDADG-like domain LAGLIDADG_WhiA PF14527.6 KIR60981.1 - 7.1e-25 86.9 0.0 1.3e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 WhiA LAGLIDADG-like domain HTH_WhiA PF02650.14 KIR60981.1 - 1.3e-18 67.1 0.0 1.9e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 WhiA C-terminal HTH domain DUF1697 PF08002.11 KIR60981.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) YcbB PF08664.10 KIR60981.1 - 1.7 8.7 3.5 42 4.2 0.4 3.1 3 0 0 3 3 3 0 YcbB domain Gp_dh_C PF02800.20 KIR60982.1 - 1e-69 233.1 0.0 1.5e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KIR60982.1 - 5.1e-38 129.5 0.1 1.5e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR60982.1 - 0.0062 15.9 0.1 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIR60982.1 - 0.023 15.5 0.0 0.058 14.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PGK PF00162.19 KIR60983.1 - 4.9e-147 489.8 0.0 5.4e-147 489.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TIM PF00121.18 KIR60984.1 - 3.8e-89 298.2 0.0 4.3e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SecG PF03840.14 KIR60985.1 - 2.5e-19 69.1 6.6 3.2e-19 68.8 6.6 1.1 1 0 0 1 1 1 1 Preprotein translocase SecG subunit Urocanase_C PF17392.2 KIR60985.1 - 0.15 11.4 0.2 0.18 11.3 0.2 1.1 1 0 0 1 1 1 0 Urocanase C-terminal domain MPS-4 PF17523.2 KIR60985.1 - 1.7 8.8 3.7 25 5.1 0.0 2.0 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 RbpA PF13397.6 KIR60986.1 - 2.1e-35 121.4 0.0 2.4e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase-binding protein Glucosamine_iso PF01182.20 KIR60987.1 - 3.6e-73 246.2 0.5 4.1e-73 246.0 0.5 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase OpcA_G6PD_assem PF10128.9 KIR60988.1 - 9.8e-77 257.9 6.8 1.2e-76 257.5 6.8 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit G6PD_C PF02781.16 KIR60989.1 - 7.5e-116 386.4 0.0 9e-116 386.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIR60989.1 - 3.2e-57 194.0 0.0 4.3e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain U62_UL91 PF17442.2 KIR60989.1 - 0.035 14.1 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins TAL_FSA PF00923.19 KIR60990.1 - 1.2e-80 270.9 0.0 1.4e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Transketolase_N PF00456.21 KIR60991.1 - 4e-130 433.7 0.0 6.1e-130 433.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KIR60991.1 - 1.1e-47 162.1 0.0 2e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIR60991.1 - 1.8e-10 40.8 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIR60991.1 - 0.0002 20.7 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase UbiA PF01040.18 KIR60992.1 - 9.6e-64 215.1 27.6 1.2e-63 214.8 27.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_syn PF06574.12 KIR60993.1 - 0.19 11.6 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD synthetase COX15-CtaA PF02628.15 KIR60994.1 - 6.6e-26 91.1 25.2 2e-20 73.2 16.6 3.0 2 1 0 2 2 2 2 Cytochrome oxidase assembly protein DUF2934 PF11154.8 KIR60994.1 - 0.18 11.5 0.2 0.32 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) HTH_5 PF01022.20 KIR60995.1 - 3.9e-05 23.4 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR60995.1 - 0.00015 21.7 1.3 0.00015 21.7 1.3 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 KIR60995.1 - 0.00031 20.6 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 KIR60995.1 - 0.0057 16.6 1.0 0.014 15.4 0.4 2.1 2 0 0 2 2 2 1 Winged helix-turn helix MarR_2 PF12802.7 KIR60995.1 - 0.0067 16.3 3.6 0.011 15.6 0.8 2.6 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 KIR60995.1 - 0.0069 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR60995.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 MarR family ATC_hydrolase PF14196.6 KIR60995.1 - 0.029 15.1 0.4 2.1 9.1 0.0 2.7 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase HTH_9 PF08221.11 KIR60995.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AT_hook PF02178.19 KIR60995.1 - 0.087 12.7 0.1 0.087 12.7 0.1 1.9 2 0 0 2 2 2 0 AT hook motif HTH_AsnC-type PF13404.6 KIR60995.1 - 0.19 11.6 0.3 0.19 11.6 0.3 2.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain UPF0051 PF01458.17 KIR60996.1 - 1.5e-76 256.9 0.5 1.9e-76 256.6 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UPF0051 PF01458.17 KIR60997.1 - 6.1e-73 245.1 0.0 7.4e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Rieske PF00355.26 KIR60998.1 - 7.4e-20 70.7 0.0 8.9e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KIR60998.1 - 4.5e-13 49.0 0.0 5.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain ABC_tran PF00005.27 KIR60999.1 - 1.7e-19 70.7 0.0 2.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR60999.1 - 3.5e-05 23.4 0.0 0.0091 15.5 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR60999.1 - 0.00055 19.6 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIR60999.1 - 0.00059 19.7 0.2 0.1 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KIR60999.1 - 0.0044 16.6 0.0 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIR60999.1 - 0.0087 16.5 0.1 0.065 13.7 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIR60999.1 - 0.022 15.3 0.1 0.037 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIR60999.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR60999.1 - 0.081 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KIR60999.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KIR60999.1 - 0.11 12.8 0.1 0.14 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KIR60999.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIR60999.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_27 PF13514.6 KIR60999.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR60999.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 KIR61000.1 - 2.4e-135 451.2 0.0 3e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR61000.1 - 0.0011 17.6 0.0 0.0025 16.4 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIR61000.1 - 0.0085 15.4 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIR61000.1 - 0.041 13.1 0.0 0.082 12.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II NifU_N PF01592.16 KIR61001.1 - 3.3e-25 88.7 0.0 3.9e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain LysE PF01810.18 KIR61002.1 - 1.5e-17 63.7 15.5 2e-17 63.3 15.5 1.1 1 0 0 1 1 1 1 LysE type translocator acVLRF1 PF18859.1 KIR61003.1 - 7.4e-44 149.2 10.5 1.2e-43 148.5 10.5 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KIR61003.1 - 3.3e-24 85.7 8.2 3.3e-24 85.7 8.2 1.4 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 baeRF_family2 PF18844.1 KIR61003.1 - 0.002 18.2 5.6 0.002 18.2 5.6 1.7 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 2 eRF1_2 PF03464.15 KIR61003.1 - 0.0036 17.6 0.0 0.0044 17.3 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 ABC_tran PF00005.27 KIR61004.1 - 6e-49 166.1 1.0 1e-22 81.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIR61004.1 - 5.9e-21 75.6 3.6 1e-05 25.5 0.0 4.2 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR61004.1 - 6.2e-09 35.6 0.1 0.15 11.4 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KIR61004.1 - 1.9e-08 34.2 2.9 3.9e-08 33.2 2.9 1.5 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KIR61004.1 - 1.5e-06 28.8 0.4 0.4 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 KIR61004.1 - 5.8e-06 26.5 0.1 0.16 12.2 0.0 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KIR61004.1 - 1e-05 26.0 5.0 0.028 14.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIR61004.1 - 1.5e-05 25.6 0.1 0.062 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIR61004.1 - 3.1e-05 23.6 0.4 0.095 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arf PF00025.21 KIR61004.1 - 0.00013 21.5 0.5 0.01 15.3 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIR61004.1 - 0.00019 21.5 0.0 0.96 9.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KIR61004.1 - 0.00021 21.6 1.2 1.3 9.3 0.1 3.6 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KIR61004.1 - 0.00045 20.2 0.3 0.43 10.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KIR61004.1 - 0.0012 19.1 2.9 1 9.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KIR61004.1 - 0.0017 18.1 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIR61004.1 - 0.0021 18.2 2.2 2.2 8.4 0.2 3.8 3 1 0 3 3 3 1 AAA domain cobW PF02492.19 KIR61004.1 - 0.0028 17.3 0.8 2.7 7.5 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 KIR61004.1 - 0.0062 16.2 6.7 0.66 9.6 0.2 3.4 4 0 0 4 4 4 2 SRP54-type protein, GTPase domain AAA PF00004.29 KIR61004.1 - 0.0062 17.0 0.4 2.7 8.4 0.0 3.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIR61004.1 - 0.0073 16.2 0.7 1.5 8.8 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KIR61004.1 - 0.0089 15.8 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 KIR61004.1 - 0.013 14.5 1.8 2.9 6.8 0.1 2.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 KIR61004.1 - 0.017 13.8 3.1 1.1 7.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 KIR61004.1 - 0.017 14.8 5.6 1.1 8.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KIR61004.1 - 0.019 14.2 0.1 2.5 7.3 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 KIR61004.1 - 0.021 14.4 2.6 0.94 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 KIR61004.1 - 0.028 14.3 0.0 8.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KIR61004.1 - 0.029 14.4 0.7 10 6.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 KIR61004.1 - 0.029 11.9 0.2 0.029 11.9 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF87 PF01935.17 KIR61004.1 - 0.056 13.5 2.0 4.8 7.2 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 KIR61004.1 - 0.063 13.0 1.3 6.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KIR61004.1 - 0.079 12.6 0.0 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DLIC PF05783.11 KIR61004.1 - 0.15 10.8 0.3 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Thymidylate_kin PF02223.17 KIR61004.1 - 0.38 10.4 2.5 5.4 6.6 0.1 2.7 2 0 0 2 2 2 0 Thymidylate kinase ECH_1 PF00378.20 KIR61006.1 - 5.3e-41 140.6 0.1 8.8e-41 139.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR61006.1 - 1.3e-24 87.4 0.1 1.8e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ABC_membrane PF00664.23 KIR61007.1 - 4.2e-41 141.4 9.9 5.4e-41 141.1 9.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR61007.1 - 7.7e-34 117.2 0.0 2.1e-33 115.7 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KIR61007.1 - 1.4e-05 24.6 0.2 0.00072 19.1 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 KIR61007.1 - 0.0011 18.2 9.5 0.003 16.9 9.5 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 KIR61007.1 - 0.0023 17.7 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KIR61007.1 - 0.0023 17.7 0.1 0.0076 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61007.1 - 0.0028 18.0 0.4 0.0067 16.8 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR61007.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KIR61007.1 - 0.022 14.5 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 KIR61007.1 - 0.025 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Cytidylate_kin PF02224.18 KIR61007.1 - 0.03 14.1 0.2 0.067 12.9 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase ABC_membrane_2 PF06472.15 KIR61007.1 - 0.032 13.6 1.9 0.08 12.3 1.9 1.5 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_22 PF13401.6 KIR61007.1 - 0.051 13.8 0.6 0.3 11.4 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR61007.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KIR61007.1 - 0.76 10.1 5.8 0.6 10.4 0.2 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AWPM-19 PF05512.11 KIR61007.1 - 1 9.6 8.6 0.064 13.4 0.8 2.7 3 0 0 3 3 3 0 AWPM-19-like family adh_short_C2 PF13561.6 KIR61008.1 - 1.7e-41 142.3 0.1 2.1e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61008.1 - 9.1e-30 103.6 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61008.1 - 3.8e-08 33.4 0.0 6.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Glyco_trans_4_4 PF13579.6 KIR61008.1 - 1.5 9.3 11.3 1.7 9.0 5.9 2.5 1 1 0 2 2 2 0 Glycosyl transferase 4-like domain Flg_hook PF02120.16 KIR61009.1 - 0.099 12.5 0.9 0.18 11.7 0.9 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK ACR_tran PF00873.19 KIR61009.1 - 0.24 9.0 0.1 0.32 8.6 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TetR_N PF00440.23 KIR61010.1 - 4.8e-17 61.5 0.7 1.2e-16 60.2 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 KIR61010.1 - 9.4e-05 22.6 9.8 9.4e-05 22.6 9.8 2.2 1 1 2 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_25 PF17933.1 KIR61010.1 - 0.002 18.4 0.8 0.4 11.0 0.1 2.2 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Hydrolase_like PF13242.6 KIR61011.1 - 5.1e-12 45.7 0.1 6.8e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 HAD-hyrolase-like HAD_2 PF13419.6 KIR61011.1 - 6.3e-12 45.9 0.0 5e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR61011.1 - 1.6e-08 35.1 0.1 5.6e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR61011.1 - 0.0027 18.1 0.4 0.0044 17.4 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RIO1 PF01163.22 KIR61012.1 - 2.1e-29 102.5 0.0 3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIR61012.1 - 0.00044 20.3 5.6 0.00061 19.8 3.6 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIR61012.1 - 0.021 14.2 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIR61012.1 - 0.049 13.0 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DUF2630 PF10944.8 KIR61013.1 - 1.1e-32 112.3 6.2 1.2e-32 112.1 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) PLN_propep PF16485.5 KIR61013.1 - 0.19 11.5 1.0 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 Protealysin propeptide Acetyltransf_1 PF00583.25 KIR61014.1 - 9.8e-15 54.8 0.1 1.1e-09 38.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR61014.1 - 3.2e-08 33.5 0.0 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR61014.1 - 8.3e-07 28.9 0.5 0.026 14.5 0.1 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 KIR61014.1 - 1.2e-06 28.9 0.1 7.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR61014.1 - 0.0016 18.5 0.2 0.025 14.7 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR61014.1 - 0.055 13.6 0.6 7.8 6.7 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KIR61014.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_6 PF13480.7 KIR61014.1 - 0.41 10.8 13.3 0.05 13.8 5.4 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain NIT PF08376.10 KIR61015.1 - 3.4e-36 125.9 19.7 3.4e-36 125.9 19.7 2.4 2 0 0 2 2 2 1 Nitrate and nitrite sensing HATPase_c PF02518.26 KIR61015.1 - 7.2e-10 39.4 0.0 1.4e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR61015.1 - 1.4e-05 25.4 0.7 5.7e-05 23.4 0.7 2.2 1 1 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 KIR61015.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Robl_LC7 PF03259.17 KIR61016.1 - 1.5e-26 92.0 0.5 2.2e-26 91.4 0.5 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF742 PF05331.11 KIR61017.1 - 1.1e-36 125.2 0.5 1.2e-36 125.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_IclR PF09339.10 KIR61017.1 - 0.0046 16.7 0.1 0.0064 16.3 0.1 1.4 1 1 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 KIR61017.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 KIR61017.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 KIR61017.1 - 0.074 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.7 KIR61017.1 - 0.085 12.8 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 KIR61017.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KIR61017.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR61017.1 - 0.16 11.4 0.7 0.38 10.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 ATP_bind_1 PF03029.17 KIR61018.1 - 3.9e-29 102.1 0.3 1.8e-27 96.7 0.3 2.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KIR61018.1 - 0.047 13.6 0.0 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KIR61018.1 - 0.1 12.1 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 KIR61018.1 - 0.14 11.8 0.3 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIR61018.1 - 0.17 10.9 0.5 0.27 10.3 0.5 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KIR61018.1 - 0.3 11.6 1.2 0.51 10.9 0.4 1.9 2 0 0 2 2 2 0 AAA domain Aconitase PF00330.20 KIR61019.1 - 5.3e-179 596.0 0.0 9.7e-179 595.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIR61019.1 - 1.4e-43 148.3 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain SNARE_assoc PF09335.11 KIR61020.1 - 1.2e-19 71.0 6.6 1.2e-19 71.0 6.6 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3096 PF11295.8 KIR61020.1 - 0.059 13.0 0.2 0.059 13.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) HTH_31 PF13560.6 KIR61021.1 - 1.5e-12 47.6 3.5 1.5e-12 47.6 3.5 2.9 2 2 1 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61021.1 - 4.4e-05 23.5 0.0 9.9e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR61021.1 - 0.035 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KIR61022.1 - 1.5e-10 41.2 2.4 1.5e-10 41.2 2.4 4.4 5 2 1 6 6 6 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61022.1 - 0.00046 20.2 0.0 0.0023 17.9 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix HTH_19 PF12844.7 KIR61022.1 - 0.049 13.7 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KIR61024.1 - 2.4e-11 43.8 0.2 2.4e-11 43.8 0.2 3.7 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61024.1 - 9.2e-10 38.4 0.3 2.6e-09 37.0 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR61024.1 - 1.5e-05 24.9 0.0 3.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR61024.1 - 0.00089 19.6 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain AAA_assoc_2 PF16193.5 KIR61024.1 - 0.03 14.7 0.5 3.7 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA C-terminal domain YdaS_antitoxin PF15943.5 KIR61024.1 - 0.1 12.5 0.4 0.73 9.8 0.0 2.6 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TPR_2 PF07719.17 KIR61024.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DSBA PF01323.20 KIR61024.1 - 3.4 7.4 5.2 4.4 7.0 4.1 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Sensor PF13796.6 KIR61025.1 - 0.019 15.0 0.7 0.022 14.8 0.7 1.1 1 0 0 1 1 1 0 Putative sensor CopD PF05425.13 KIR61025.1 - 0.056 13.9 2.7 0.072 13.5 2.6 1.4 1 1 0 1 1 1 0 Copper resistance protein D Form-deh_trans PF09163.11 KIR61025.1 - 0.088 12.6 1.8 0.15 11.9 1.8 1.3 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Peptidase_C92 PF05708.12 KIR61026.1 - 0.064 13.4 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family SnoaL_4 PF13577.6 KIR61027.1 - 0.0063 16.6 0.0 0.0091 16.1 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KIR61027.1 - 0.036 14.7 0.4 0.055 14.1 0.3 1.4 1 1 0 1 1 1 0 SnoaL-like domain CBM_2 PF00553.19 KIR61028.1 - 1.6e-08 34.8 0.1 2.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Cellulose binding domain Alpha-amylase PF00128.24 KIR61029.1 - 1.4e-85 287.8 0.0 1.2e-78 265.0 0.0 3.8 4 0 0 4 4 4 2 Alpha amylase, catalytic domain DUF3372 PF11852.8 KIR61029.1 - 2.2e-58 196.4 0.0 1.7e-56 190.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3372) PUD PF03714.14 KIR61029.1 - 7.4e-44 148.5 0.7 1.8e-21 76.8 0.6 2.8 2 0 0 2 2 2 2 Bacterial pullanase-associated domain Pullulanase_N2 PF17967.1 KIR61029.1 - 4.8e-35 120.8 1.5 4.8e-35 120.8 1.5 3.6 4 0 0 4 4 4 1 Pullulanase N2 domain CBM_48 PF02922.18 KIR61029.1 - 1.4e-09 38.2 0.1 4.9e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Big_7 PF17957.1 KIR61029.1 - 3.3e-05 24.5 2.3 3.3e-05 24.5 2.3 2.8 3 0 0 3 3 3 1 Bacterial Ig domain Malt_amylase_C PF16657.5 KIR61029.1 - 7.9e-05 22.7 0.0 0.0059 16.7 0.0 2.6 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_30C PF17189.4 KIR61029.1 - 0.016 15.4 0.1 5.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain DUF3459 PF11941.8 KIR61029.1 - 0.045 14.1 2.2 0.68 10.3 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KIR61029.1 - 0.22 10.5 0.0 8.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Peptidase_M24 PF00557.24 KIR61032.1 - 2.3e-45 154.9 0.1 3.1e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIR61032.1 - 8e-22 77.3 0.0 1.4e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain LPMO_10 PF03067.15 KIR61033.1 - 3.6e-40 138.7 0.3 1e-39 137.2 0.0 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_2 PF00553.19 KIR61033.1 - 1.1e-23 83.4 9.0 2.8e-23 82.1 9.0 1.7 1 0 0 1 1 1 1 Cellulose binding domain PfkB PF00294.24 KIR61034.1 - 3.2e-48 164.6 0.8 3.6e-48 164.4 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Lactamase_B PF00753.27 KIR61035.1 - 2.7e-23 83.0 9.3 5.2e-23 82.1 9.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily 4HBT PF03061.22 KIR61036.1 - 3.7e-07 30.4 1.4 4.4e-07 30.2 0.7 1.5 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 KIR61036.1 - 0.0058 16.8 0.1 0.0096 16.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_2 PF13279.6 KIR61036.1 - 0.058 13.9 0.0 0.068 13.7 0.0 1.3 1 1 0 1 1 1 0 Thioesterase-like superfamily CysG_dimeriser PF10414.9 KIR61036.1 - 0.076 12.7 0.2 0.076 12.7 0.2 2.0 1 1 1 2 2 2 0 Sirohaem synthase dimerisation region PAP2_3 PF14378.6 KIR61037.1 - 3.6e-28 98.5 19.8 3.6e-28 98.5 19.8 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KIR61037.1 - 3.4e-09 36.6 5.6 3.4e-09 36.6 5.6 3.4 2 1 2 4 4 4 1 PAP2 superfamily PAP2_C PF14360.6 KIR61037.1 - 4.3e-06 27.2 2.8 4.3e-06 27.2 2.8 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF423 PF04241.15 KIR61037.1 - 0.066 13.4 5.2 0.17 12.1 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Fungal_trans_2 PF11951.8 KIR61037.1 - 3.7 6.3 4.5 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain bPH_2 PF03703.14 KIR61038.1 - 1.5e-15 57.1 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain UVR PF02151.19 KIR61038.1 - 0.25 11.1 0.2 0.44 10.4 0.2 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif AAA_3 PF07726.11 KIR61039.1 - 1.9e-62 208.9 0.1 4.7e-62 207.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIR61039.1 - 5e-19 67.9 1.6 5e-19 67.9 1.6 2.5 1 1 1 2 2 2 1 AAA lid domain AAA_5 PF07728.14 KIR61039.1 - 5e-14 52.5 0.0 1.2e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KIR61039.1 - 0.0003 20.6 0.1 0.0017 18.1 0.0 2.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.29 KIR61039.1 - 0.007 16.8 0.0 0.021 15.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIR61039.1 - 0.12 11.7 0.2 0.93 8.8 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIR61039.1 - 0.14 11.9 0.1 2.2 8.0 0.1 2.6 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF58 PF01882.18 KIR61040.1 - 1.9e-18 66.5 0.5 4e-18 65.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 KIR61041.1 - 3.7e-19 69.3 0.0 8.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIR61041.1 - 7.8e-18 65.3 0.0 1.1e-17 64.9 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 KIR61041.1 - 3.2e-07 30.6 11.8 3.2e-07 30.6 11.8 1.9 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal DUF4131 PF13567.6 KIR61041.1 - 0.00076 19.2 1.7 0.00076 19.2 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) DUF1194 PF06707.11 KIR61041.1 - 0.01 15.0 1.1 0.65 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) VWA_3 PF13768.6 KIR61041.1 - 0.12 12.3 0.2 0.49 10.3 0.2 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4191 PF13829.6 KIR61041.1 - 0.27 10.6 1.0 1.1 8.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) FixQ PF05545.11 KIR61041.1 - 4.2 7.4 5.6 6.9 6.7 1.2 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ YwiC PF14256.6 KIR61041.1 - 5 7.4 11.5 0.47 10.8 2.6 2.9 2 1 1 3 3 3 0 YwiC-like protein adh_short_C2 PF13561.6 KIR61043.1 - 7.2e-60 202.4 3.7 1.2e-59 201.7 3.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61043.1 - 1.7e-51 174.5 1.0 3.2e-51 173.6 1.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61043.1 - 3.3e-19 69.5 0.5 1.1e-14 54.7 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KIR61043.1 - 3.9e-05 23.2 0.1 5.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR61043.1 - 0.025 13.7 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 KIR61043.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.6 KIR61043.1 - 0.17 11.7 2.0 0.24 11.3 2.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 KIR61044.1 - 9.3e-69 231.5 0.0 1e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61044.1 - 4.3e-14 52.4 0.0 5.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61044.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 KR domain Ferrochelatase PF00762.19 KIR61045.1 - 4.6e-97 324.9 0.0 5.2e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Hydrolase_6 PF13344.6 KIR61046.1 - 1.4e-27 95.8 0.0 3.1e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR61046.1 - 1.7e-22 79.2 0.0 5e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KIR61046.1 - 7.2e-08 32.7 0.0 4.4e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR61046.1 - 3.6e-07 30.7 0.0 3.8e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KIR61046.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DUF3097 PF11296.8 KIR61048.1 - 2.2e-123 410.8 0.9 2.4e-123 410.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) Beta-lactamase PF00144.24 KIR61049.1 - 1.1e-54 186.0 11.2 1.1e-54 186.0 11.2 1.4 2 0 0 2 2 2 1 Beta-lactamase Peptidase_S11 PF00768.20 KIR61049.1 - 0.0084 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase NfeD PF01957.18 KIR61050.1 - 4.4e-18 65.4 0.8 4.4e-18 65.4 0.8 1.6 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding Band_7 PF01145.25 KIR61051.1 - 6.6e-33 114.2 1.2 6.6e-33 114.2 1.2 2.8 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KIR61051.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Melibiase_2 PF16499.5 KIR61052.1 - 4.6e-54 183.5 0.7 7.6e-54 182.8 0.7 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 KIR61052.1 - 1.1e-29 103.3 10.3 1.9e-29 102.5 10.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR61052.1 - 1.5e-24 86.5 26.0 9.8e-12 45.4 4.5 3.8 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Melibiase_C PF17801.1 KIR61052.1 - 1.8e-13 50.3 0.1 4.6e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIR61052.1 - 1.7e-05 24.0 0.1 3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 KIR61052.1 - 0.0014 18.0 0.0 0.0068 15.7 0.0 1.9 2 0 0 2 2 2 1 Glycoside hydrolase 97 Raffinose_syn PF05691.12 KIR61052.1 - 0.066 11.0 0.6 0.1 10.4 0.6 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 MucBP_2 PF17965.1 KIR61052.1 - 0.13 12.8 1.8 7.5 7.2 0.4 2.5 2 0 0 2 2 2 0 Mucin binding domain ET PF01684.16 KIR61052.1 - 1.2 9.5 4.7 22 5.4 0.1 3.1 1 1 2 3 3 3 0 ET module Transgly PF00912.22 KIR61053.1 - 4.9e-60 202.0 0.0 8.4e-60 201.3 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KIR61053.1 - 1e-24 87.3 0.1 2e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain SpoU_methylase PF00588.19 KIR61054.1 - 5.8e-28 97.8 0.0 8.2e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KIR61054.1 - 0.0016 18.7 0.0 0.0046 17.2 0.0 1.8 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Arginosuc_synth PF00764.19 KIR61055.1 - 5.1e-57 193.9 0.0 6.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase PucR PF07905.11 KIR61056.1 - 5.5e-37 126.6 0.3 3.3e-36 124.1 0.0 2.4 3 0 0 3 3 3 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 KIR61056.1 - 6.3e-16 57.9 3.2 1.5e-15 56.7 2.1 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 KIR61056.1 - 5.6e-08 33.0 21.0 3.9e-06 27.1 13.9 4.0 3 1 0 3 3 3 2 GGDEF-like domain HTH_28 PF13518.6 KIR61056.1 - 0.067 13.3 5.2 6.4 7.0 0.4 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_1 PF00126.27 KIR61056.1 - 0.13 12.2 3.3 0.27 11.2 0.7 2.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Mur_ligase_M PF08245.12 KIR61058.1 - 7.4e-18 65.2 0.0 1.4e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Peptidase_M50B PF13398.6 KIR61059.1 - 0.016 14.8 10.8 0.016 14.8 10.8 1.5 1 1 1 2 2 2 0 Peptidase M50B-like RseC_MucC PF04246.12 KIR61059.1 - 7 6.6 10.0 75 3.3 10.0 2.1 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC TetR_N PF00440.23 KIR61061.1 - 1.2e-07 31.4 0.1 2.5e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Aminotran_3 PF00202.21 KIR61063.1 - 9.4e-90 301.2 0.0 1.2e-89 300.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIR61063.1 - 0.00037 19.8 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_5 PF00266.19 KIR61063.1 - 0.11 11.4 0.2 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aldedh PF00171.22 KIR61064.1 - 5.3e-142 473.6 0.1 6.5e-142 473.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIR61064.1 - 0.00094 18.3 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Acyl_transf_3 PF01757.22 KIR61065.1 - 1.4e-19 70.4 23.5 1.4e-19 70.4 23.5 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF4231 PF14015.6 KIR61065.1 - 0.46 11.0 1.5 7.3 7.1 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) BcrAD_BadFG PF01869.20 KIR61067.1 - 3e-18 66.3 0.8 3.8e-18 65.9 0.8 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 KIR61067.1 - 0.0033 16.9 0.1 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 ROK family SIS PF01380.22 KIR61068.1 - 1.2e-18 67.2 0.0 1.9e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 KIR61068.1 - 5.4e-15 55.1 0.0 1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 KIR61068.1 - 1.7e-06 28.1 1.9 8.4e-05 22.6 0.0 2.5 1 1 1 2 2 2 1 SIS domain HTH_24 PF13412.6 KIR61068.1 - 0.0006 19.3 0.0 0.0058 16.2 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR61068.1 - 0.0039 17.0 3.2 0.012 15.4 0.0 3.0 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61068.1 - 0.0048 16.7 3.0 0.29 11.0 0.4 3.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.22 KIR61068.1 - 0.012 15.6 0.1 0.061 13.3 0.0 2.3 3 0 0 3 3 3 0 MarR family MarR_2 PF12802.7 KIR61068.1 - 0.038 13.9 0.2 0.038 13.9 0.2 2.8 4 0 0 4 4 4 0 MarR family PELOTA_1 PF15608.6 KIR61068.1 - 0.15 11.9 1.0 1.1 9.1 0.2 2.3 2 0 0 2 2 2 0 PELOTA RNA binding domain SIS_2 PF13580.6 KIR61069.1 - 4.9e-40 136.7 0.2 2.3e-39 134.6 0.1 1.9 2 0 0 2 2 2 1 SIS domain SIS PF01380.22 KIR61069.1 - 0.083 12.7 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 SIS domain SBP_bac_8 PF13416.6 KIR61070.1 - 1.4e-23 84.1 11.6 2.1e-23 83.6 11.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR61070.1 - 6.6e-21 75.6 16.0 6.6e-21 75.6 16.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein Mod_r PF07200.13 KIR61070.1 - 0.036 14.2 0.4 0.063 13.4 0.4 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TFIIS_M PF07500.14 KIR61070.1 - 0.11 13.0 0.2 0.22 12.0 0.2 1.4 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain BPD_transp_1 PF00528.22 KIR61071.1 - 2.9e-10 40.2 34.4 5.2e-09 36.1 34.4 2.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR61072.1 - 2.5e-14 53.4 14.0 2.5e-14 53.4 14.0 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DNA_pol_A PF00476.20 KIR61073.1 - 2.2e-22 79.6 0.0 3.5e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase family A NTP_transf_3 PF12804.7 KIR61074.1 - 2.4e-32 112.5 4.4 2.9e-32 112.2 4.4 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 KIR61074.1 - 2.1e-05 24.3 0.2 3.1e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) CbiX PF01903.17 KIR61074.1 - 0.091 13.1 0.2 3 8.2 0.0 2.3 1 1 1 2 2 2 0 CbiX NTP_transferase PF00483.23 KIR61074.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Glyoxalase_6 PF18029.1 KIR61075.1 - 1.1e-28 100.1 5.5 2.9e-28 98.8 5.5 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain WYL PF13280.6 KIR61076.1 - 3.2e-34 118.5 4.4 6e-34 117.6 4.4 1.5 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 KIR61076.1 - 7.7e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 KIR61076.1 - 2.1e-06 28.0 0.3 4.6e-06 26.9 0.1 1.7 2 0 0 2 2 1 1 Transcriptional regulator MarR_2 PF12802.7 KIR61076.1 - 6.8e-05 22.7 1.6 0.00026 20.8 1.6 2.0 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.12 KIR61076.1 - 0.0032 17.2 0.1 0.0053 16.5 0.1 1.3 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 KIR61076.1 - 0.0045 16.7 1.3 0.018 14.8 1.3 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 KIR61076.1 - 0.015 15.4 0.5 0.015 15.4 0.5 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 KIR61076.1 - 0.015 15.1 1.6 0.015 15.1 1.6 2.3 3 0 0 3 3 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR61076.1 - 0.017 14.7 0.2 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HrcA_DNA-bdg PF03444.15 KIR61076.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_39 PF14090.6 KIR61076.1 - 0.036 13.8 0.1 0.098 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIR61076.1 - 0.052 13.2 0.1 0.052 13.2 0.1 2.6 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_28 PF13518.6 KIR61076.1 - 0.087 13.0 0.3 0.087 13.0 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain WYL_2 PF10902.8 KIR61076.1 - 0.094 13.1 1.3 0.19 12.1 1.3 1.5 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold HTH_Mga PF08280.11 KIR61076.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_AsnC-type PF13404.6 KIR61076.1 - 0.16 11.8 12.4 0.035 13.9 5.6 3.2 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain CotH PF08757.11 KIR61076.1 - 0.27 10.7 0.3 0.46 10.0 0.3 1.3 1 0 0 1 1 1 0 CotH kinase protein PaaX PF07848.12 KIR61076.1 - 0.73 10.1 3.0 9.3 6.6 0.1 2.9 3 0 0 3 3 3 0 PaaX-like protein MarR PF01047.22 KIR61077.1 - 5.4e-10 39.1 1.5 6.8e-10 38.7 0.0 1.9 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.7 KIR61077.1 - 1.5e-08 34.3 0.5 4.5e-08 32.9 0.3 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KIR61077.1 - 3.3e-07 30.7 0.1 7.2e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_1 PF00126.27 KIR61077.1 - 0.0029 17.5 1.7 0.02 14.8 0.1 2.5 2 1 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PadR PF03551.14 KIR61077.1 - 0.013 15.5 0.0 0.095 12.7 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family FliT PF05400.13 KIR61077.1 - 0.1 13.4 4.4 0.17 12.7 2.2 2.2 1 1 1 2 2 2 0 Flagellar protein FliT EHN PF06441.12 KIR61078.1 - 8.2e-41 138.8 0.4 1.9e-40 137.5 0.1 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIR61078.1 - 3.2e-13 49.9 0.1 9.3e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Phage_rep_O PF04492.13 KIR61078.1 - 0.23 12.1 0.0 0.42 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication protein O Glyco_hydro_1 PF00232.18 KIR61079.1 - 4.3e-153 510.0 0.0 5.2e-153 509.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_31 PF01055.26 KIR61080.1 - 1.8e-119 399.8 0.2 2.2e-119 399.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIR61080.1 - 1.1e-17 64.1 0.2 3.8e-17 62.4 0.2 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like BPD_transp_1 PF00528.22 KIR61081.1 - 1.8e-14 53.9 15.0 1.8e-14 53.9 15.0 2.5 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DHHC PF01529.20 KIR61081.1 - 4.9 7.3 6.0 39 4.3 4.2 3.0 3 1 1 4 4 4 0 DHHC palmitoyltransferase BPD_transp_1 PF00528.22 KIR61082.1 - 3.6e-16 59.4 8.6 3.6e-16 59.4 8.6 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 KIR61083.1 - 1.4e-32 113.9 15.7 2.2e-32 113.3 15.7 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61083.1 - 1.4e-30 107.1 10.4 1.9e-30 106.7 10.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR61083.1 - 7.9e-05 22.2 0.2 0.0053 16.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein LRR_10 PF18805.1 KIR61083.1 - 0.042 13.5 1.9 0.05 13.2 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat LPAM_2 PF13627.6 KIR61083.1 - 6.3 6.8 5.0 12 5.9 5.0 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Peripla_BP_3 PF13377.6 KIR61084.1 - 6.3e-27 94.9 1.7 6.3e-27 94.9 1.7 1.9 2 1 1 3 3 3 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR61084.1 - 2e-19 69.1 0.7 1.1e-18 66.8 0.4 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 KIR61084.1 - 4.3e-16 59.2 0.1 5.6e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_31 PF13560.6 KIR61084.1 - 0.014 15.7 4.6 0.015 15.6 0.2 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_53 PF18606.1 KIR61084.1 - 1 9.1 3.4 23 4.7 0.0 2.6 3 0 0 3 3 3 0 Zap helix turn helix N-terminal domain YdjM PF04307.14 KIR61085.1 - 7.3e-32 110.1 3.8 1.3e-30 105.9 3.8 2.0 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF2371 PF10177.9 KIR61085.1 - 0.07 13.3 2.9 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) DUF1275 PF06912.11 KIR61085.1 - 0.27 11.1 11.6 0.07 13.0 6.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1275) Pkinase PF00069.25 KIR61086.1 - 1.2e-41 142.8 0.0 1.6e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR61086.1 - 8.7e-26 90.7 0.0 1.1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIR61086.1 - 3.1e-07 30.0 0.0 0.00062 19.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIR61086.1 - 0.0012 18.9 0.7 0.0012 18.9 0.7 3.2 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR61086.1 - 0.022 13.6 0.0 0.048 12.4 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KIR61086.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIR61086.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Glycos_transf_1 PF00534.20 KIR61087.1 - 6.3e-41 139.8 0.0 9e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR61087.1 - 7.8e-33 113.9 5.7 7.8e-33 113.9 5.7 2.3 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIR61087.1 - 7.8e-30 104.0 1.1 2.7e-29 102.3 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR61087.1 - 2e-28 99.8 28.2 3e-27 96.0 12.0 2.5 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 KIR61087.1 - 1.8e-18 67.1 10.8 1.4e-17 64.2 5.7 2.8 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 KIR61087.1 - 4.6e-12 46.2 0.0 2.9e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR61087.1 - 8.6e-06 25.8 0.0 0.00012 22.1 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase 4-like GDE_C PF06202.14 KIR61088.1 - 5.3e-91 305.4 0.0 7.3e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase GDE_N PF12439.8 KIR61088.1 - 7.7e-54 182.4 0.0 1.3e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme N terminal Glyco_hydro_63 PF03200.16 KIR61089.1 - 5.9e-10 38.5 0.0 2e-06 26.9 0.0 4.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain HAD_2 PF13419.6 KIR61090.1 - 9e-11 42.2 0.0 2.7e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR61090.1 - 5e-10 40.0 0.0 7.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR61090.1 - 5.3e-06 27.0 0.7 7.9e-06 26.4 0.7 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR61090.1 - 9.1e-06 25.7 0.0 2.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIR61090.1 - 0.067 13.3 0.1 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase IL10 PF00726.17 KIR61090.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 DSBA PF01323.20 KIR61093.1 - 9e-07 28.9 0.8 1e-05 25.4 0.8 1.9 1 1 0 1 1 1 1 DSBA-like thioredoxin domain SBP_bac_1 PF01547.25 KIR61094.1 - 2.8e-25 89.9 4.9 3.9e-25 89.5 4.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61094.1 - 1.7e-24 87.2 3.1 2.1e-24 86.8 3.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein K_channel_TID PF07941.11 KIR61094.1 - 0.0079 16.6 1.4 0.017 15.6 1.4 1.5 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain Big_3_3 PF13750.6 KIR61094.1 - 0.02 14.5 0.0 0.19 11.3 0.0 2.5 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) BPD_transp_1 PF00528.22 KIR61095.1 - 1.1e-09 38.2 18.6 1.1e-09 38.2 18.6 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR61096.1 - 9.3e-22 77.7 11.7 9.3e-22 77.7 11.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KIR61097.1 - 7.5e-31 107.5 0.0 1.3e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 KIR61097.1 - 2.4e-11 44.3 0.2 1.1e-10 42.1 0.1 2.3 2 0 0 2 2 1 1 MalK OB fold domain TOBE_2 PF08402.10 KIR61097.1 - 6.1e-07 29.5 1.3 0.0021 18.2 0.0 3.5 2 1 1 3 3 3 2 TOBE domain SMC_N PF02463.19 KIR61097.1 - 2.5e-05 23.9 0.1 0.0007 19.1 0.1 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIR61097.1 - 0.00014 21.8 0.0 0.00036 20.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase CysA_C_terminal PF17850.1 KIR61097.1 - 0.0002 21.9 3.4 0.00061 20.3 0.4 2.9 3 0 0 3 3 2 1 CysA C-terminal regulatory domain AAA_21 PF13304.6 KIR61097.1 - 0.0002 21.3 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KIR61097.1 - 0.0029 17.5 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIR61097.1 - 0.0037 17.7 0.3 0.0092 16.4 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIR61097.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR61097.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S17 PF00366.20 KIR61097.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 AIG1 PF04548.16 KIR61097.1 - 0.031 13.6 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA_25 PF13481.6 KIR61097.1 - 0.034 13.7 0.1 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIR61097.1 - 0.038 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KIR61097.1 - 0.06 13.8 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIR61097.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIR61097.1 - 0.092 13.0 0.1 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIR61097.1 - 0.13 12.3 0.2 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KIR61097.1 - 0.13 12.4 0.0 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIR61097.1 - 0.22 11.9 0.0 0.44 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HAD_2 PF13419.6 KIR61098.1 - 3.5e-23 82.6 0.0 4e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR61098.1 - 5.9e-14 52.9 0.0 5e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR61098.1 - 4.6e-07 30.4 0.0 5.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR61098.1 - 3.9e-05 23.6 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like FMN_red PF03358.15 KIR61099.1 - 3.3e-16 59.4 0.0 4.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIR61099.1 - 4.5e-10 39.6 0.0 6.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KIR61099.1 - 1.3e-09 38.5 0.1 4.2e-06 27.0 0.0 2.4 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_1 PF00258.25 KIR61099.1 - 5e-05 23.5 0.2 0.00022 21.4 0.2 2.1 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 KIR61099.1 - 0.16 11.7 0.1 11 5.7 0.0 2.3 1 1 1 2 2 2 0 Flavodoxin domain Chorismate_bind PF00425.18 KIR61100.1 - 1.2e-45 156.1 0.0 1.5e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KIR61100.1 - 4.1e-18 65.8 0.0 8.5e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIR61100.1 - 0.15 11.8 0.2 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 FGGY_N PF00370.21 KIR61101.1 - 2e-18 66.9 0.0 2.5e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIR61101.1 - 5.1e-11 42.7 0.2 9e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain NIT PF08376.10 KIR61102.1 - 9.1e-26 91.7 22.4 9.1e-26 91.7 22.4 2.2 2 0 0 2 2 2 1 Nitrate and nitrite sensing HAMP PF00672.25 KIR61102.1 - 0.00015 22.1 1.0 0.00094 19.5 1.0 2.6 1 1 0 1 1 1 1 HAMP domain HATPase_c PF02518.26 KIR61102.1 - 0.00051 20.5 0.0 0.00098 19.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR61102.1 - 0.0035 17.3 1.3 1.7 8.7 0.2 2.8 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain Robl_LC7 PF03259.17 KIR61103.1 - 3.7e-22 77.9 0.6 5.3e-22 77.4 0.6 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF2173 PF09941.9 KIR61103.1 - 0.0024 18.1 0.1 0.0038 17.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2173) DUF1464 PF07318.12 KIR61103.1 - 0.0059 15.8 0.5 0.0067 15.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) Glyco_hydro_1 PF00232.18 KIR61104.1 - 1.7e-156 521.2 0.0 1.6e-155 518.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_48 PF02011.15 KIR61105.1 - 6.7e-302 1002.7 33.0 6.7e-302 1002.7 33.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 48 CBM_2 PF00553.19 KIR61105.1 - 2.6e-29 101.5 11.6 2.6e-29 101.5 11.6 4.0 3 1 0 4 4 4 1 Cellulose binding domain TcfC PF16967.5 KIR61105.1 - 0.0082 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 E-set like domain PAP2 PF01569.21 KIR61106.1 - 2.4e-11 43.5 8.0 2.4e-11 43.5 8.0 3.6 1 1 3 4 4 4 1 PAP2 superfamily PAP2_3 PF14378.6 KIR61106.1 - 0.0039 16.9 20.7 0.042 13.5 20.7 2.7 1 1 0 1 1 1 1 PAP2 superfamily MDMPI_N PF11716.8 KIR61107.1 - 6.1e-24 85.3 19.1 6.1e-24 85.3 19.1 1.8 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DUF664 PF04978.12 KIR61107.1 - 0.00037 20.9 4.2 0.04 14.3 1.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR61107.1 - 0.0019 18.7 7.1 0.005 17.3 6.5 2.1 1 1 0 1 1 1 1 DinB superfamily PT-TG PF14449.6 KIR61107.1 - 0.026 14.4 0.1 0.067 13.1 0.1 1.8 1 0 0 1 1 1 0 Pre-toxin TG Bac_luciferase PF00296.20 KIR61108.1 - 6.3e-52 176.9 15.4 8.3e-52 176.5 15.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short PF00106.25 KIR61109.1 - 5.5e-44 150.0 1.7 7e-44 149.6 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR61109.1 - 5.7e-34 117.7 8.1 7.3e-34 117.3 8.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR61109.1 - 1.6e-09 37.9 4.9 2.7e-09 37.2 4.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR61109.1 - 0.00017 21.2 0.9 0.00039 20.0 0.5 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIR61109.1 - 0.00018 21.8 1.0 0.00032 20.9 1.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIR61109.1 - 0.0013 19.3 1.2 0.0027 18.3 1.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 KIR61109.1 - 0.032 14.3 1.1 0.053 13.6 1.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIR61109.1 - 0.045 14.0 0.6 0.1 12.9 0.6 1.6 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KIR61109.1 - 0.059 12.7 1.5 0.11 11.8 1.5 1.4 1 0 0 1 1 1 0 ThiF family Polysacc_synt_2 PF02719.15 KIR61109.1 - 0.061 12.4 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIR61109.1 - 0.076 12.4 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KIR61109.1 - 0.12 12.3 1.8 0.18 11.7 1.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIR61109.1 - 0.16 11.5 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.17 KIR61109.1 - 0.17 10.9 3.0 0.34 10.0 3.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Transglut_core PF01841.19 KIR61110.1 - 6.6e-20 71.6 0.0 1.4e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DNA_pol3_gamma3 PF12169.8 KIR61110.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III DUF58 PF01882.18 KIR61111.1 - 4.1e-21 75.0 0.1 8.7e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 CARDB PF07705.11 KIR61111.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 CARDB DUF1731 PF08338.11 KIR61111.1 - 0.027 14.3 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) AAA_3 PF07726.11 KIR61112.1 - 1.4e-62 209.4 0.0 2.3e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIR61112.1 - 4e-18 65.0 2.1 4e-18 65.0 2.1 2.1 2 1 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 KIR61112.1 - 5e-15 55.7 0.0 7.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIR61112.1 - 1.4e-06 28.7 0.0 3.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIR61112.1 - 2.7e-05 23.9 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 KIR61112.1 - 5.2e-05 23.0 0.0 0.00052 19.8 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 KIR61112.1 - 0.00023 20.3 0.0 0.00055 19.1 0.0 1.6 1 1 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KIR61112.1 - 0.0016 17.9 0.2 0.38 10.1 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KIR61112.1 - 0.024 15.0 0.0 0.088 13.2 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain GHL10 PF02638.15 KIR61112.1 - 0.036 13.2 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 AAA_2 PF07724.14 KIR61112.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) CPT PF07931.12 KIR61112.1 - 0.053 13.4 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 KIR61112.1 - 0.13 12.2 0.1 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 KIR61112.1 - 0.22 11.2 2.2 1.6 8.4 0.1 3.0 3 1 1 4 4 4 0 AAA domain AAA_18 PF13238.6 KIR61112.1 - 0.23 12.0 0.0 0.34 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain fn3 PF00041.21 KIR61113.1 - 1.6e-30 105.3 6.7 7.2e-10 39.1 0.0 5.3 4 2 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KIR61113.1 - 2.2e-10 41.0 8.9 0.0031 18.1 2.2 5.1 3 2 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain DUF4959 PF16323.5 KIR61113.1 - 0.00011 22.5 0.5 0.56 10.6 0.1 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4959) Arylsulfotran_N PF17425.2 KIR61113.1 - 0.00096 19.1 0.5 0.23 11.5 0.2 3.1 3 0 0 3 3 3 1 Arylsulfotransferase Ig-like domain DUF2369 PF10179.9 KIR61113.1 - 0.055 13.9 0.0 6.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Apyrase PF06079.11 KIR61113.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Apyrase TQ PF18202.1 KIR61113.1 - 0.14 12.7 3.9 5.4 7.6 0.0 3.2 2 1 1 3 3 3 0 T-Q ester bond containing domain CARDB PF07705.11 KIR61113.1 - 5.1 7.4 8.7 8.8 6.6 0.8 4.3 3 1 1 4 4 4 0 CARDB PRIMA1 PF16101.5 KIR61113.1 - 5.7 7.0 13.4 0.26 11.3 5.1 2.8 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 HTH_1 PF00126.27 KIR61115.1 - 1.8e-20 72.7 1.3 1.8e-20 72.7 1.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 KIR61115.1 - 5e-19 68.5 7.4 5e-19 68.5 7.4 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_30 PF13556.6 KIR61115.1 - 0.0014 18.4 0.1 0.0014 18.4 0.1 2.2 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 KIR61115.1 - 0.024 14.5 0.3 0.19 11.6 0.0 2.7 3 0 0 3 3 3 0 MarR family adh_short_C2 PF13561.6 KIR61116.1 - 3.3e-53 180.7 1.0 4.2e-53 180.3 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61116.1 - 2.3e-42 144.7 0.2 2.9e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61116.1 - 1e-15 58.1 3.9 3.8e-15 56.2 3.9 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIR61116.1 - 4.6e-05 22.9 0.0 5.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIR61116.1 - 0.00096 18.7 0.0 0.03 13.8 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ThuA PF06283.11 KIR61117.1 - 1.2e-81 274.0 2.1 1.4e-81 273.8 0.7 1.8 2 0 0 2 2 2 1 Trehalose utilisation DUF1080 PF06439.11 KIR61117.1 - 1e-37 130.1 1.1 2.1e-37 129.0 0.1 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1080) RicinB_lectin_2 PF14200.6 KIR61117.1 - 5e-31 107.3 21.9 8.9e-14 52.0 3.4 4.3 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CBM_6 PF03422.15 KIR61117.1 - 8.7e-29 100.4 1.1 8.7e-29 100.4 1.1 4.1 4 1 1 5 5 5 1 Carbohydrate binding module (family 6) Ricin_B_lectin PF00652.22 KIR61117.1 - 4.1e-28 98.2 5.8 6.5e-28 97.5 5.8 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF5010_C PF18099.1 KIR61117.1 - 0.00089 19.4 3.7 0.0012 19.0 0.1 3.1 4 0 0 4 4 4 1 DUF5010 C-terminal domain ET PF01684.16 KIR61117.1 - 0.054 13.8 4.1 20 5.6 0.5 3.3 1 1 2 3 3 3 0 ET module GSDH PF07995.11 KIR61118.1 - 3.6e-37 128.4 0.0 1.4e-34 119.9 0.1 2.5 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase RicinB_lectin_2 PF14200.6 KIR61118.1 - 1.1e-31 109.4 22.0 5.7e-14 52.6 1.4 4.4 3 1 2 5 5 5 3 Ricin-type beta-trefoil lectin domain-like CBM_6 PF03422.15 KIR61118.1 - 5.3e-31 107.5 1.3 5.3e-31 107.5 1.3 3.9 3 0 0 3 3 3 1 Carbohydrate binding module (family 6) Ricin_B_lectin PF00652.22 KIR61118.1 - 1.4e-29 102.9 6.3 2.6e-29 102.0 6.3 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PKD PF00801.20 KIR61118.1 - 1.2e-10 41.1 4.7 1.2e-10 41.1 4.7 3.3 3 0 0 3 3 3 1 PKD domain DUF5010_C PF18099.1 KIR61118.1 - 2.7e-05 24.3 0.6 0.00016 21.7 0.2 2.5 2 0 0 2 2 2 1 DUF5010 C-terminal domain Big_7 PF17957.1 KIR61118.1 - 8.2e-05 23.3 0.2 8.2e-05 23.3 0.2 4.5 4 1 0 4 4 4 1 Bacterial Ig domain ET PF01684.16 KIR61118.1 - 0.025 14.9 3.2 11 6.5 0.2 3.6 1 1 2 3 3 3 0 ET module ADH_zinc_N_2 PF13602.6 KIR61119.1 - 2.1e-19 70.9 0.2 3.9e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR61119.1 - 6.3e-16 58.5 0.4 1e-15 57.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR61119.1 - 2.4e-08 33.8 0.1 2.4e-07 30.6 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KIR61119.1 - 0.0082 16.1 4.7 0.011 15.7 3.9 1.5 1 1 0 1 1 1 1 NAD(P)H-binding ADH_N_2 PF16884.5 KIR61119.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase HxlR PF01638.17 KIR61120.1 - 1.3e-26 92.2 0.0 1.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 KIR61120.1 - 5.9e-07 29.3 0.2 1e-06 28.5 0.2 1.4 1 1 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR61120.1 - 0.00088 19.3 0.2 0.0035 17.4 0.2 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.14 KIR61120.1 - 0.00089 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_5 PF01022.20 KIR61120.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GntR PF00392.21 KIR61120.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 KIR61120.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DHDPS PF00701.22 KIR61121.1 - 2e-44 151.5 0.0 2.3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AP_endonuc_2 PF01261.24 KIR61124.1 - 1e-22 80.6 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UCR_Fe-S_N PF10399.9 KIR61124.1 - 0.019 14.3 1.5 0.036 13.4 1.5 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 KIR61124.1 - 0.081 12.8 6.1 0.16 11.9 6.1 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Wzy_C PF04932.15 KIR61125.1 - 6.6e-16 58.3 1.2 6.6e-16 58.3 1.2 5.4 4 2 1 5 5 5 1 O-Antigen ligase Wzz PF02706.15 KIR61126.1 - 5e-07 29.9 0.2 5e-07 29.9 0.2 2.5 3 1 1 4 4 4 1 Chain length determinant protein Exonuc_VII_L PF02601.15 KIR61126.1 - 0.019 14.6 3.1 0.03 13.9 3.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2564 PF10819.8 KIR61126.1 - 3.2 8.2 9.4 2.1 8.8 1.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) Polysacc_synt PF01943.17 KIR61127.1 - 6e-20 71.8 8.0 6e-20 71.8 8.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 KIR61127.1 - 1e-16 61.1 0.5 1e-16 61.1 0.5 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 KIR61127.1 - 2.1e-15 57.0 19.8 2.1e-15 57.0 19.8 3.4 3 0 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KIR61127.1 - 3e-12 46.5 17.0 6.6e-10 38.9 5.4 2.7 2 0 0 2 2 2 2 MatE Glyco_hydro_44 PF12891.7 KIR61128.1 - 0.0046 16.9 1.9 0.019 14.9 0.1 2.5 2 1 0 2 2 2 1 Glycoside hydrolase family 44 Glyco_hydro_39 PF01229.17 KIR61128.1 - 0.0079 14.8 0.0 0.01 14.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_42 PF02449.15 KIR61128.1 - 0.16 11.3 0.1 4.5 6.5 0.0 2.6 2 1 0 2 2 2 0 Beta-galactosidase Sulfotransfer_3 PF13469.6 KIR61129.1 - 3.5e-40 138.7 0.2 7.2e-40 137.7 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR61129.1 - 2.6e-10 40.2 0.0 5.9e-09 35.8 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KIR61130.1 - 1.1e-10 42.3 0.0 0.00044 20.7 0.0 2.7 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR61130.1 - 0.00045 19.8 0.0 0.043 13.3 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Glycos_transf_1 PF00534.20 KIR61131.1 - 1.5e-33 115.7 0.0 2.1e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR61131.1 - 1.7e-29 102.9 0.2 3.9e-29 101.8 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR61131.1 - 6e-18 65.4 2.8 6e-18 65.4 2.8 2.3 2 2 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIR61131.1 - 3.3e-17 63.4 10.8 3.3e-17 63.4 10.8 3.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIR61131.1 - 1.2e-11 44.9 0.0 3.5e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR61131.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KIR61131.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Sulfotransfer_3 PF13469.6 KIR61132.1 - 1.4e-22 81.2 0.1 7.4e-22 78.8 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR61132.1 - 4.6e-10 39.4 0.0 1e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain TrkA_N PF02254.18 KIR61132.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Peptidase_S15 PF02129.18 KIR61133.1 - 2.1e-52 178.4 0.4 3.1e-52 177.8 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KIR61133.1 - 4.9e-34 118.2 0.1 7.6e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 KIR61133.1 - 4.2e-06 26.4 0.7 1.3e-05 24.8 0.7 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_64 PF16483.5 KIR61134.1 - 1.2e-98 330.9 0.0 1.7e-98 330.3 0.0 1.2 1 0 0 1 1 1 1 Beta-1,3-glucanase Ricin_B_lectin PF00652.22 KIR61134.1 - 4.5e-23 81.9 6.9 9.2e-23 80.9 6.9 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR61134.1 - 4.9e-17 62.4 13.4 1.4e-08 35.3 1.2 4.2 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Fe-ADH PF00465.19 KIR61135.1 - 2e-106 355.9 4.2 2.3e-106 355.7 4.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIR61135.1 - 6.1e-15 55.6 4.7 2.9e-08 33.7 0.7 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 KIR61136.1 - 4.9e-160 533.0 0.0 5.9e-160 532.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KIR61136.1 - 0.021 14.3 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF3102 PF11300.8 KIR61136.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Moricin PF06451.11 KIR61136.1 - 0.23 11.3 1.1 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Moricin ABC_tran PF00005.27 KIR61137.1 - 9.8e-28 97.4 0.0 1.5e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 KIR61137.1 - 2.9e-06 27.4 0.4 9.7e-06 25.7 0.3 2.0 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 KIR61137.1 - 7.7e-06 25.9 0.8 0.012 15.5 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 KIR61137.1 - 2.2e-05 25.2 0.0 0.00017 22.4 0.0 2.4 2 0 0 2 2 2 1 MalK OB fold domain AAA_23 PF13476.6 KIR61137.1 - 0.0025 18.3 0.0 0.0037 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR61137.1 - 0.003 17.8 0.1 0.0065 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR61137.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61137.1 - 0.011 16.2 0.5 0.024 15.0 0.5 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 KIR61137.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR61137.1 - 0.017 14.9 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TOBE PF03459.17 KIR61137.1 - 0.024 14.9 0.2 0.076 13.3 0.2 1.9 1 0 0 1 1 1 0 TOBE domain RsgA_GTPase PF03193.16 KIR61137.1 - 0.026 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KIR61137.1 - 0.06 13.6 0.2 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIR61137.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIR61137.1 - 0.079 13.1 0.3 0.2 11.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain CysA_C_terminal PF17850.1 KIR61137.1 - 0.085 13.4 0.3 0.84 10.3 0.0 2.7 3 0 0 3 3 2 0 CysA C-terminal regulatory domain SMC_N PF02463.19 KIR61137.1 - 0.098 12.1 0.0 1.5 8.2 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KIR61137.1 - 0.23 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KIR61138.1 - 1.9e-28 99.7 0.0 2.8e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 KIR61138.1 - 1.1e-11 44.8 1.0 4.5e-11 42.7 1.0 2.1 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 KIR61138.1 - 2e-07 31.2 0.0 0.011 15.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 KIR61138.1 - 8e-07 29.8 0.2 3.1e-06 27.9 0.2 2.1 1 0 0 1 1 1 1 MalK OB fold domain CysA_C_terminal PF17850.1 KIR61138.1 - 8.6e-06 26.2 0.3 8.6e-06 26.2 0.3 2.8 3 0 0 3 3 3 1 CysA C-terminal regulatory domain RsgA_GTPase PF03193.16 KIR61138.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KIR61138.1 - 0.0043 17.6 0.0 0.0068 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61138.1 - 0.0046 17.3 0.4 0.01 16.2 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KIR61138.1 - 0.0071 16.6 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR61138.1 - 0.012 15.8 0.2 0.047 13.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIR61138.1 - 0.015 14.8 0.0 0.29 10.5 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIR61138.1 - 0.015 15.7 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIR61138.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 KIR61138.1 - 0.029 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIR61138.1 - 0.093 12.7 0.6 0.99 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIR61138.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR61138.1 - 0.2 11.6 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_27 PF13514.6 KIR61138.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 KIR61139.1 - 2e-19 70.1 14.7 2e-19 70.1 14.7 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 KIR61140.1 - 8.2e-31 108.1 9.2 1.3e-30 107.4 9.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61140.1 - 2.9e-26 93.0 7.7 4.6e-26 92.3 7.7 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein FCD PF07729.12 KIR61141.1 - 2.3e-24 86.2 14.2 3.7e-24 85.5 14.2 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KIR61141.1 - 1.4e-16 59.9 0.6 8.5e-14 51.0 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KIR61141.1 - 1.5e-07 31.2 3.3 2.6e-07 30.4 0.1 2.6 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 KIR61141.1 - 1.8e-05 24.2 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 KIR61141.1 - 0.00018 21.6 0.1 0.0058 16.8 0.0 2.4 2 0 0 2 2 2 1 PaaX-like protein HTH_29 PF13551.6 KIR61141.1 - 0.00099 19.1 0.2 0.0049 16.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 KIR61141.1 - 0.0017 18.3 0.0 0.0046 16.9 0.0 1.8 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 KIR61141.1 - 0.0026 17.6 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 KIR61141.1 - 0.0028 18.1 0.1 0.009 16.5 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_DeoR PF08220.12 KIR61141.1 - 0.0067 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61141.1 - 0.0094 15.8 0.1 0.031 14.1 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 KIR61141.1 - 0.019 15.3 0.0 0.067 13.5 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator HTH_28 PF13518.6 KIR61141.1 - 0.02 15.0 0.0 0.069 13.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain SgrR_N PF12793.7 KIR61141.1 - 0.024 14.8 0.0 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term Fe_dep_repress PF01325.19 KIR61141.1 - 0.036 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 KIR61141.1 - 0.036 14.0 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 KIR61141.1 - 0.037 14.2 0.3 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 DprA winged helix domain EAP30 PF04157.16 KIR61141.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family MarR PF01047.22 KIR61141.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.12 KIR61141.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain HTH_41 PF14502.6 KIR61141.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DJ-1_PfpI PF01965.24 KIR61142.1 - 1.4e-39 135.6 0.0 1.6e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_1 PF00561.20 KIR61143.1 - 1.9e-22 80.2 0.5 1.7e-16 60.6 2.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR61143.1 - 3.1e-19 70.5 23.3 3.6e-19 70.2 23.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR61143.1 - 2.6e-18 66.2 0.3 3.4e-18 65.8 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIR61143.1 - 2.2e-07 30.8 0.4 3.8e-07 30.0 0.4 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KIR61143.1 - 4.2e-06 26.7 0.2 0.0068 16.2 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KIR61143.1 - 0.00047 20.0 0.1 0.0012 18.6 0.1 1.7 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S15 PF02129.18 KIR61143.1 - 0.0006 19.5 0.1 0.0013 18.4 0.1 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 KIR61143.1 - 0.001 19.2 0.6 0.0013 18.9 0.6 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 KIR61143.1 - 0.0033 17.3 0.4 0.0055 16.6 0.4 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 KIR61143.1 - 0.0036 17.1 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KIR61143.1 - 0.014 15.3 0.1 0.39 10.6 0.1 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 KIR61143.1 - 0.021 14.4 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 KIR61143.1 - 0.024 14.1 0.5 4.5 6.7 0.2 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KIR61143.1 - 0.039 14.1 0.1 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein Acyl_transf_1 PF00698.21 KIR61143.1 - 0.042 13.4 1.1 0.07 12.6 1.1 1.3 1 0 0 1 1 1 0 Acyl transferase domain DLH PF01738.18 KIR61143.1 - 0.058 12.9 0.1 0.91 9.0 0.1 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 KIR61143.1 - 0.25 10.0 0.8 0.46 9.1 0.5 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ser_hydrolase PF06821.13 KIR61143.1 - 0.38 10.6 3.6 0.34 10.7 0.9 2.2 1 1 1 2 2 2 0 Serine hydrolase HTH_20 PF12840.7 KIR61144.1 - 5.2e-12 45.6 0.3 5.2e-12 45.6 0.3 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 KIR61144.1 - 1.1e-10 41.2 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KIR61144.1 - 3.3e-08 33.3 0.4 7.2e-08 32.2 0.2 1.6 1 1 1 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 KIR61144.1 - 2.6e-05 24.1 0.1 6.3e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 KIR61144.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Glyoxalase PF00903.25 KIR61145.1 - 9.5e-10 38.8 0.0 2e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIR61145.1 - 7.9e-05 22.9 0.0 0.0069 16.6 0.0 2.2 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR61145.1 - 0.0067 17.2 0.1 0.014 16.2 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain AbiEi_4 PF13338.6 KIR61145.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.6 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Glyoxalase_2 PF12681.7 KIR61145.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain Peptidase_M23 PF01551.22 KIR61146.1 - 2.6e-21 75.6 0.8 4e-21 75.0 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M23 UCR_Fe-S_N PF10399.9 KIR61146.1 - 0.014 14.8 2.5 0.043 13.2 2.5 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Biotin_lipoyl_2 PF13533.6 KIR61146.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like ketoacyl-synt PF00109.26 KIR61147.1 - 4.7e-183 606.3 9.1 2.2e-92 309.2 0.2 4.0 4 0 0 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR61147.1 - 4.6e-177 588.2 1.4 4.8e-90 302.3 0.9 2.4 2 0 0 2 2 2 2 Acyl transferase domain KR PF08659.10 KIR61147.1 - 2.9e-118 392.2 0.9 3.9e-59 199.6 0.1 3.6 3 0 0 3 3 3 2 KR domain PS-DH PF14765.6 KIR61147.1 - 7.8e-106 353.6 20.8 1.1e-54 185.7 6.4 2.8 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KIR61147.1 - 7.2e-87 287.3 3.9 8.2e-43 145.2 0.0 3.3 3 0 0 3 3 2 2 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR61147.1 - 1.5e-34 118.9 0.0 7.2e-16 58.6 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR61147.1 - 5.3e-28 97.2 0.0 4e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KIR61147.1 - 2.7e-22 80.2 0.2 1.5e-21 77.8 0.2 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIR61147.1 - 3e-18 66.0 0.0 1.1e-07 31.5 0.0 3.1 3 0 0 3 3 3 2 short chain dehydrogenase ADH_zinc_N PF00107.26 KIR61147.1 - 1.1e-15 57.7 2.1 4.1e-15 55.9 0.1 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 KIR61147.1 - 7.5e-14 51.7 2.7 3.2e-06 26.7 0.2 2.7 2 0 0 2 2 2 2 Thiolase, N-terminal domain Docking PF08990.11 KIR61147.1 - 1.2e-09 37.6 6.9 3.6e-09 36.1 6.9 2.0 1 0 0 1 1 1 1 Erythronolide synthase docking Epimerase PF01370.21 KIR61147.1 - 3.5e-09 36.5 0.4 0.00059 19.4 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIR61147.1 - 2.6e-06 26.8 0.0 0.0088 15.2 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein SAT PF16073.5 KIR61147.1 - 1.8e-05 24.6 6.4 0.41 10.3 0.0 4.7 4 1 1 5 5 4 1 Starter unit:ACP transacylase in aflatoxin biosynthesis GDP_Man_Dehyd PF16363.5 KIR61147.1 - 9.1e-05 22.0 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 KIR61147.1 - 0.00015 21.6 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 KIR61147.1 - 0.0025 17.4 3.2 0.71 9.4 0.2 2.4 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 KIR61147.1 - 0.072 12.1 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIR61147.1 - 0.16 11.1 4.0 1.2 8.3 0.3 2.5 2 0 0 2 2 2 0 Male sterility protein ACP_syn_III PF08545.10 KIR61147.1 - 0.2 11.5 7.2 4.4 7.2 0.1 3.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GBP_PSP PF02425.15 KIR61147.1 - 0.22 11.2 2.1 3.9 7.2 0.2 2.7 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide RmlD_sub_bind PF04321.17 KIR61147.1 - 3.4 6.7 4.9 1.9 7.5 0.2 2.8 3 0 0 3 3 3 0 RmlD substrate binding domain Thioesterase PF00975.20 KIR61148.1 - 1.5e-52 179.0 0.0 1.7e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KIR61148.1 - 5.1e-13 50.1 8.6 7.3e-13 49.6 8.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR61148.1 - 7e-07 29.1 0.0 0.00094 18.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR61148.1 - 0.00041 19.7 0.0 0.0096 15.2 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KIR61148.1 - 0.001 18.7 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KIR61148.1 - 0.023 14.6 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 KIR61148.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1205 PF06722.12 KIR61149.1 - 3.2e-17 62.4 0.0 7.4e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1205) UDPGT PF00201.18 KIR61149.1 - 4.2e-08 32.4 0.0 9.6e-07 27.9 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.6 KIR61149.1 - 1.2e-05 25.4 0.0 0.00084 19.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_tran_28_C PF04101.16 KIR61149.1 - 2.5e-05 24.3 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 KIR61149.1 - 0.0002 21.8 2.4 0.0002 21.8 2.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR61149.1 - 0.0024 17.9 0.4 0.015 15.3 0.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 PP-binding PF00550.25 KIR61150.1 - 6.8e-05 23.2 0.2 8.2e-05 22.9 0.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.10 KIR61152.1 - 2.9e-16 59.1 0.0 6.7e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 KIR61152.1 - 2.9e-08 33.4 1.8 6e-08 32.4 1.4 1.6 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Thiolase_N PF00108.23 KIR61152.1 - 5.2e-07 29.3 0.2 7.2e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III_C PF08541.10 KIR61152.1 - 1.3e-06 28.5 0.0 6.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 KIR61152.1 - 1.2e-05 24.7 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ketoacyl-synt PF00109.26 KIR61152.1 - 0.00033 20.3 10.0 0.004 16.8 9.7 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KIR61152.1 - 0.013 14.2 0.0 0.026 13.2 0.0 1.4 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 KIR61153.1 - 0 1219.1 12.0 1.9e-92 309.4 0.2 7.3 8 0 0 8 8 8 4 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR61153.1 - 8.2e-247 817.4 15.9 1e-77 261.8 0.0 4.4 4 0 0 4 4 4 4 Acyl transferase domain KR PF08659.10 KIR61153.1 - 4.5e-190 626.2 23.6 2.3e-57 193.8 1.6 5.5 5 0 0 5 5 5 4 KR domain Ketoacyl-synt_C PF02801.22 KIR61153.1 - 3e-181 591.7 17.2 2.5e-45 153.3 0.2 5.2 4 0 0 4 4 4 4 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR61153.1 - 4.4e-175 581.0 34.1 2.4e-54 184.6 4.3 4.8 4 0 0 4 4 4 4 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIR61153.1 - 5.1e-67 223.4 0.0 7.1e-18 65.1 0.0 5.2 5 0 0 5 5 5 4 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR61153.1 - 1.6e-54 182.1 2.1 2.4e-12 47.0 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site adh_short PF00106.25 KIR61153.1 - 1.4e-33 116.0 6.2 1.6e-10 40.8 0.2 4.4 4 0 0 4 4 4 3 short chain dehydrogenase Thiolase_N PF00108.23 KIR61153.1 - 5.4e-29 101.3 6.7 1.7e-06 27.6 0.1 5.0 4 0 0 4 4 4 4 Thiolase, N-terminal domain Epimerase PF01370.21 KIR61153.1 - 1.5e-12 47.6 9.6 0.0018 17.8 0.3 3.5 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR61153.1 - 4.6e-12 46.0 0.1 0.0088 15.5 0.0 3.3 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase Docking PF08990.11 KIR61153.1 - 5.9e-10 38.6 8.1 2.8e-09 36.4 8.1 2.3 1 0 0 1 1 1 1 Erythronolide synthase docking Polysacc_synt_2 PF02719.15 KIR61153.1 - 1.4e-09 37.5 0.0 0.016 14.4 0.0 3.2 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIR61153.1 - 8.6e-06 25.1 8.3 0.014 14.5 0.3 3.7 3 0 0 3 3 3 3 Male sterility protein NmrA PF05368.13 KIR61153.1 - 0.00012 21.7 12.3 0.33 10.5 0.4 3.6 3 0 0 3 3 3 3 NmrA-like family ACP_syn_III PF08545.10 KIR61153.1 - 0.0018 18.1 17.8 2.2 8.2 0.1 6.5 6 0 0 6 6 5 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_C PF02803.18 KIR61153.1 - 0.0025 17.5 0.1 15 5.2 0.1 4.5 4 0 0 4 4 4 0 Thiolase, C-terminal domain 3Beta_HSD PF01073.19 KIR61153.1 - 0.011 14.8 0.2 3.5 6.5 0.0 3.1 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family GBP_PSP PF02425.15 KIR61153.1 - 0.61 9.8 2.9 7 6.4 0.2 2.9 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Semialdhyde_dh PF01118.24 KIR61153.1 - 1 9.8 4.1 13 6.3 0.1 3.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DegT_DnrJ_EryC1 PF01041.17 KIR61154.1 - 3.6e-116 388.4 0.0 4.1e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIR61154.1 - 0.00014 20.9 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDP_Man_Dehyd PF16363.5 KIR61155.1 - 2.2e-79 267.3 0.0 2.5e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIR61155.1 - 5.6e-64 215.9 0.0 6.7e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR61155.1 - 7.3e-21 74.4 0.0 9.4e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIR61155.1 - 1e-17 64.2 0.0 6.3e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIR61155.1 - 2.7e-13 49.7 0.0 1.1e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIR61155.1 - 1.6e-12 47.2 0.1 1.7e-11 43.8 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KIR61155.1 - 2.6e-09 37.2 0.1 4.5e-08 33.2 0.1 2.4 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KIR61155.1 - 0.0031 17.0 1.7 0.079 12.4 1.7 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KIR61155.1 - 0.037 13.6 0.4 0.057 13.0 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family NTP_transferase PF00483.23 KIR61156.1 - 2.5e-54 184.5 0.0 3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR61156.1 - 2.4e-10 41.0 0.1 4.5e-10 40.1 0.1 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Acyl_transf_3 PF01757.22 KIR61157.1 - 1.2e-27 96.9 45.2 1.5e-27 96.6 45.2 1.1 1 0 0 1 1 1 1 Acyltransferase family DegT_DnrJ_EryC1 PF01041.17 KIR61158.1 - 1.5e-85 287.6 0.0 1.8e-85 287.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIR61158.1 - 3e-07 29.7 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIR61158.1 - 0.0079 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Sigma70_r4 PF04545.16 KIR61158.1 - 0.17 11.4 0.0 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1205 PF06722.12 KIR61159.1 - 8.7e-16 57.8 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1205) UDPGT PF00201.18 KIR61159.1 - 3.3e-10 39.4 0.0 5.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIR61159.1 - 1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 KIR61159.1 - 0.0081 16.2 2.9 0.02 14.9 1.8 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 GFO_IDH_MocA PF01408.22 KIR61160.1 - 5.4e-22 78.9 0.0 1.4e-21 77.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold IPPT PF01715.17 KIR61160.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 IPP transferase DUF2117 PF09890.9 KIR61160.1 - 0.25 10.8 0.0 0.41 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) dTDP_sugar_isom PF00908.17 KIR61161.1 - 1.1e-49 168.4 0.0 1.2e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase TcpA PF05946.12 KIR61161.1 - 0.009 16.1 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 1 Toxin-coregulated pilus subunit TcpA BTAD PF03704.17 KIR61162.1 - 6.5e-33 114.2 7.8 9.3e-33 113.7 7.8 1.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KIR61162.1 - 1.5e-11 44.2 0.3 4.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal TPR_19 PF14559.6 KIR61162.1 - 0.0062 17.0 3.2 0.016 15.7 0.9 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIR61162.1 - 0.011 16.3 5.4 0.98 10.1 2.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIR61162.1 - 0.025 14.6 1.3 9.6 6.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIR61162.1 - 0.054 14.3 7.4 1.9 9.5 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.10 KIR61162.1 - 0.066 12.7 0.7 0.3 10.5 0.7 1.8 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 KIR61162.1 - 0.11 13.1 6.0 5.7 7.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.28 KIR61162.1 - 0.12 12.4 0.6 0.28 11.3 0.4 1.7 1 1 0 1 1 1 0 NUDIX domain TPR_12 PF13424.6 KIR61162.1 - 0.18 12.1 6.8 6.4 7.2 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_alpha PF07733.12 KIR61166.1 - 3.2e-98 328.5 0.0 4.7e-98 327.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 KIR61166.1 - 9.3e-56 187.7 0.0 1.6e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 KIR61166.1 - 1.1e-45 155.9 0.0 2e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 KIR61166.1 - 7.1e-25 87.1 0.0 1.6e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 KIR61166.1 - 4.7e-06 26.5 0.0 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain B1 PF02246.15 KIR61166.1 - 0.075 13.1 0.2 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein L b1 domain Aminotran_5 PF00266.19 KIR61168.1 - 3.9e-28 98.5 0.0 4.8e-26 91.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR61168.1 - 2.4e-07 29.7 0.0 3.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIR61168.1 - 1.7 7.9 5.6 3.8 6.7 5.6 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 KIR61170.1 - 5.3e-58 196.6 50.5 9.6e-57 192.5 41.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR61170.1 - 7.1e-08 31.7 18.5 0.00023 20.2 4.6 2.3 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 KIR61170.1 - 8.3e-06 24.5 18.5 1.9e-05 23.3 4.8 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 KIR61170.1 - 9.3e-06 24.8 6.9 9.3e-06 24.8 6.9 3.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KIR61170.1 - 1.5e-05 23.8 13.7 1.5e-05 23.8 13.7 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 KIR61170.1 - 2.5e-05 23.8 9.9 2.5e-05 23.8 9.9 3.4 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KIR61170.1 - 0.0064 14.8 4.8 0.031 12.6 0.2 3.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2275 PF10039.9 KIR61170.1 - 4.6 7.3 7.4 3.8 7.6 0.1 3.0 4 0 0 4 4 4 0 Predicted integral membrane protein (DUF2275) TetR_C_11 PF16859.5 KIR61171.1 - 2.7e-19 69.6 2.0 2.7e-19 69.6 2.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR61171.1 - 5.8e-12 45.2 0.1 1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 KIR61171.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_6 PF13977.6 KIR61171.1 - 0.0023 18.2 0.4 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal HTH_7 PF02796.15 KIR61171.1 - 0.0023 18.0 0.1 0.011 15.8 0.1 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_6 PF01418.17 KIR61171.1 - 0.0037 17.2 0.1 0.0059 16.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_32 PF13565.6 KIR61171.1 - 0.015 15.9 0.8 0.043 14.4 0.2 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_30 PF13556.6 KIR61172.1 - 1.9e-19 69.2 2.4 3.5e-19 68.3 0.0 2.8 4 0 0 4 4 4 1 PucR C-terminal helix-turn-helix domain GAF_2 PF13185.6 KIR61172.1 - 2e-18 67.0 1.0 2e-18 67.0 1.0 3.2 3 0 0 3 3 3 1 GAF domain GAF PF01590.26 KIR61172.1 - 9e-16 58.7 0.1 3.2e-15 56.9 0.1 2.0 1 0 0 1 1 1 1 GAF domain GGDEF_2 PF17853.1 KIR61172.1 - 6.6e-15 55.4 4.5 6.6e-15 55.4 4.5 4.2 3 2 1 4 4 4 1 GGDEF-like domain GAF_3 PF13492.6 KIR61172.1 - 4.3e-12 46.5 0.7 9.5e-11 42.2 0.0 2.9 2 1 0 2 2 2 1 GAF domain HTH_1 PF00126.27 KIR61172.1 - 0.0025 17.7 0.0 0.019 14.9 0.0 2.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 KIR61172.1 - 0.078 12.8 1.2 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain adh_short_C2 PF13561.6 KIR61173.1 - 1.6e-46 158.8 2.1 3.9e-46 157.5 2.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61173.1 - 3.1e-43 147.5 0.1 4.8e-43 146.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KIR61173.1 - 7.8e-11 41.9 0.7 2.9e-10 40.0 0.2 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIR61173.1 - 3.5e-08 33.6 0.5 6.9e-08 32.6 0.5 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIR61173.1 - 4.3e-07 30.0 0.9 4.3e-07 30.0 0.9 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIR61173.1 - 4.8e-05 22.9 0.0 8.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AdoHcyase_NAD PF00670.21 KIR61173.1 - 0.00064 19.8 0.2 0.0013 18.9 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 KIR61173.1 - 0.0011 19.3 0.5 0.0021 18.3 0.5 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KIR61173.1 - 0.0013 19.2 0.2 0.003 18.1 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KIR61173.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIR61173.1 - 0.0018 17.5 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KIR61173.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KIR61173.1 - 0.0022 18.6 0.1 0.0061 17.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain ApbA PF02558.16 KIR61173.1 - 0.004 16.8 0.8 0.0077 15.9 0.7 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 KIR61173.1 - 0.0047 17.6 0.1 0.01 16.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 KIR61173.1 - 0.0087 15.7 3.4 0.012 15.2 3.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Polysacc_synt_2 PF02719.15 KIR61173.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 KIR61173.1 - 0.017 15.6 0.4 0.028 14.8 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KIR61173.1 - 0.018 14.3 2.9 0.03 13.6 2.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIR61173.1 - 0.022 14.6 0.3 0.049 13.5 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIR61173.1 - 0.041 13.9 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KIR61173.1 - 0.042 13.4 0.7 0.071 12.7 0.7 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_8 PF13450.6 KIR61173.1 - 0.093 13.0 1.8 0.22 11.8 1.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIR61173.1 - 1.3 7.6 3.5 2 7.0 3.5 1.2 1 0 0 1 1 1 0 HI0933-like protein RuvC PF02075.17 KIR61174.1 - 4.7e-50 169.3 0.0 5.4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC RuvA_N PF01330.21 KIR61175.1 - 1.9e-19 69.5 0.0 3.4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 RuvA N terminal domain HHH_5 PF14520.6 KIR61175.1 - 1.3e-17 64.1 0.1 5.3e-17 62.2 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 KIR61175.1 - 1.3e-11 44.7 0.3 1.1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 KIR61175.1 - 5.3e-06 26.0 0.3 0.096 12.6 0.1 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 KIR61175.1 - 4e-05 23.8 0.0 0.056 13.7 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_2 PF12826.7 KIR61175.1 - 0.0044 17.1 0.0 2.6 8.2 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix motif IMS_HHH PF11798.8 KIR61175.1 - 0.0044 17.3 0.0 0.23 11.9 0.0 2.8 2 0 0 2 2 2 1 IMS family HHH motif Transposase_20 PF02371.16 KIR61175.1 - 0.029 14.7 0.1 12 6.2 0.0 2.7 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family Cdd1 PF11731.8 KIR61175.1 - 0.095 12.9 0.0 1.9 8.8 0.0 2.3 1 1 1 2 2 2 0 Pathogenicity locus HHH_8 PF14716.6 KIR61175.1 - 0.13 12.7 0.1 1.7 9.1 0.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain DUF2642 PF10842.8 KIR61175.1 - 0.19 11.6 0.2 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) RuvB_N PF05496.12 KIR61176.1 - 3.3e-73 244.7 0.0 4.8e-73 244.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 KIR61176.1 - 3.5e-31 106.8 1.2 6.3e-31 105.9 1.2 1.5 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 KIR61176.1 - 4.8e-22 77.6 0.0 8.3e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 KIR61176.1 - 2.1e-17 63.8 0.0 5.8e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIR61176.1 - 9.5e-07 29.3 0.8 2.8e-05 24.6 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KIR61176.1 - 1.1e-06 28.6 0.1 6.4e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIR61176.1 - 0.00024 21.4 0.2 0.058 13.7 0.0 2.6 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIR61176.1 - 0.00032 20.1 1.1 0.16 11.4 0.2 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KIR61176.1 - 0.0007 19.5 0.4 0.0059 16.5 0.1 2.2 1 1 1 2 2 2 1 NTPase T2SSE PF00437.20 KIR61176.1 - 0.00078 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KIR61176.1 - 0.0018 18.3 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KIR61176.1 - 0.0026 17.0 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KIR61176.1 - 0.0028 17.8 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KIR61176.1 - 0.0032 17.4 0.0 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KIR61176.1 - 0.0033 17.3 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIR61176.1 - 0.004 16.9 0.0 1.6 8.4 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 KIR61176.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIR61176.1 - 0.0051 16.1 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.22 KIR61176.1 - 0.0062 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 KIR61176.1 - 0.013 15.9 0.2 0.41 11.0 0.0 2.3 1 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIR61176.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KIR61176.1 - 0.02 15.1 0.1 0.054 13.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIR61176.1 - 0.036 13.8 0.2 0.35 10.6 0.2 2.4 1 1 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 KIR61176.1 - 0.076 12.1 0.1 2.7 7.0 0.1 2.2 1 1 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 KIR61176.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIR61176.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KIR61176.1 - 0.21 10.7 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIR61176.1 - 0.25 11.1 0.0 0.55 9.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIR61176.1 - 0.27 11.0 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIR61176.1 - 0.27 11.2 0.0 11 6.0 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit YajC PF02699.15 KIR61177.1 - 5.8e-27 93.4 0.0 7.1e-27 93.1 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit SecD_SecF PF02355.16 KIR61178.1 - 7.3e-09 35.3 9.7 1.3e-08 34.5 9.7 1.3 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 KIR61178.1 - 7e-06 25.2 18.4 1.4e-05 24.2 18.4 1.4 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 KIR61178.1 - 0.00057 19.3 0.1 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 SecD/SecF GG Motif POTRA PF07244.15 KIR61178.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat SOG2 PF10428.9 KIR61178.1 - 5.2 6.2 5.7 7.3 5.7 5.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SecD_SecF PF02355.16 KIR61179.1 - 4.9e-47 159.8 8.2 7.3e-47 159.2 8.2 1.2 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 KIR61179.1 - 0.0001 21.7 0.1 0.00025 20.4 0.1 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif LPG_synthase_TM PF03706.13 KIR61179.1 - 0.21 11.1 20.7 0.026 14.1 1.2 2.9 3 0 0 3 3 3 0 Lysylphosphatidylglycerol synthase TM region DUF1071 PF06378.11 KIR61179.1 - 0.23 11.0 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Pribosyltran PF00156.27 KIR61180.1 - 2.7e-15 56.2 0.4 3.7e-15 55.8 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIR61180.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase HD_4 PF13328.6 KIR61181.1 - 2.5e-46 157.3 0.2 2.5e-46 157.3 0.2 2.1 2 0 0 2 2 2 1 HD domain RelA_SpoT PF04607.17 KIR61181.1 - 2e-38 131.2 0.0 3.7e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 KIR61181.1 - 6.2e-24 83.8 0.0 2.1e-23 82.1 0.0 2.0 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 KIR61181.1 - 2.9e-16 59.8 0.1 7.7e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 KIR61181.1 - 7.8e-13 48.0 0.4 1.9e-12 46.7 0.4 1.7 1 0 0 1 1 1 1 ACT domain HD PF01966.22 KIR61181.1 - 7.3e-11 42.3 1.4 2.2e-10 40.8 0.3 2.4 3 0 0 3 3 3 1 HD domain DNA_pol3_gamma3 PF12169.8 KIR61181.1 - 0.0048 16.8 0.0 0.035 14.0 0.1 2.4 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III ThiS PF02597.20 KIR61181.1 - 0.0094 16.6 0.0 0.074 13.7 0.0 2.7 2 0 0 2 2 2 1 ThiS family Ub-Mut7C PF14451.6 KIR61181.1 - 0.17 11.8 0.1 0.91 9.4 0.0 2.3 2 0 0 2 2 2 0 Mut7-C ubiquitin Pro_isomerase PF00160.21 KIR61182.1 - 1.1e-28 100.6 0.0 1.7e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3040 PF11239.8 KIR61182.1 - 0.14 12.4 1.1 0.26 11.6 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Pro_isomerase PF00160.21 KIR61183.1 - 3.6e-19 69.6 0.0 4.6e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3040 PF11239.8 KIR61183.1 - 0.22 11.8 1.1 0.4 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Lactamase_B PF00753.27 KIR61184.1 - 7.2e-22 78.4 6.3 4.2e-21 75.9 6.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR61184.1 - 6e-06 25.9 0.0 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIR61184.1 - 0.0025 17.7 0.0 0.0045 16.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain tRNA-synt_His PF13393.6 KIR61185.1 - 6e-26 91.4 0.0 7.3e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KIR61185.1 - 2.3e-06 27.6 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIR61185.1 - 0.00016 21.7 0.0 0.00042 20.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FA_desaturase_2 PF03405.14 KIR61186.1 - 1.1e-79 267.6 0.0 1.4e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Pro_Al_protease PF02983.14 KIR61187.1 - 1.5e-14 53.7 5.8 1.5e-14 53.7 5.8 3.4 2 1 1 3 3 3 1 Alpha-lytic protease prodomain Pico_P2A PF00947.19 KIR61187.1 - 1.4 8.9 5.2 1.1 9.3 2.5 2.0 2 0 0 2 2 2 0 Picornavirus core protein 2A MFS_3 PF05977.13 KIR61188.1 - 1.1e-160 535.5 33.3 1.3e-160 535.3 33.3 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KIR61188.1 - 2.1e-27 96.0 53.1 1.3e-25 90.1 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABM PF03992.16 KIR61188.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF998 PF06197.13 KIR61189.1 - 3.4e-23 82.2 39.9 7.3e-23 81.1 39.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF998) tRNA-synt_2 PF00152.20 KIR61190.1 - 5.3e-100 334.5 0.0 6.9e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIR61190.1 - 3.9e-16 58.8 0.0 1e-15 57.5 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain GAD PF02938.14 KIR61190.1 - 3.7e-15 55.9 0.1 7.9e-15 54.9 0.1 1.6 2 0 0 2 2 2 1 GAD domain tRNA-synt_2d PF01409.20 KIR61190.1 - 0.033 13.7 0.0 1.6 8.2 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) EutN_CcmL PF03319.13 KIR61190.1 - 0.098 13.3 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome tRNA-synt_2b PF00587.25 KIR61190.1 - 0.21 11.5 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) RmlD_sub_bind PF04321.17 KIR61191.1 - 1e-31 110.1 0.1 6.3e-31 107.5 0.1 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIR61191.1 - 7.2e-16 58.4 0.2 1.4e-15 57.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR61191.1 - 1.7e-07 31.3 5.2 2e-07 31.1 5.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIR61191.1 - 7.5e-05 22.3 0.1 0.0012 18.3 0.1 2.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIR61191.1 - 0.28 10.7 2.4 0.76 9.3 2.4 1.8 1 1 0 1 1 1 0 NmrA-like family adh_short PF00106.25 KIR61191.1 - 0.52 9.7 7.7 0.1 12.0 0.9 2.6 3 1 0 3 3 3 0 short chain dehydrogenase adh_short_C2 PF13561.6 KIR61191.1 - 0.58 9.7 6.3 1.2 8.7 0.3 2.7 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase MgsA_C PF12002.8 KIR61193.1 - 4.1e-68 228.5 0.5 1.4e-67 226.8 0.0 1.9 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KIR61193.1 - 5.7e-25 87.5 2.3 5.7e-25 87.5 2.3 2.6 2 1 1 3 3 2 1 AAA C-terminal domain AAA PF00004.29 KIR61193.1 - 2.9e-18 66.6 0.0 9.9e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIR61193.1 - 1.7e-12 47.4 0.0 3.7e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIR61193.1 - 4.4e-09 36.5 0.0 3.4e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIR61193.1 - 3.6e-07 30.7 4.7 0.0029 18.0 0.0 3.2 1 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KIR61193.1 - 3e-06 27.0 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIR61193.1 - 1.2e-05 24.9 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIR61193.1 - 1.3e-05 25.5 0.0 0.039 14.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 KIR61193.1 - 3.1e-05 23.8 0.0 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KIR61193.1 - 0.00097 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIR61193.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KIR61193.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIR61193.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 KIR61193.1 - 0.0021 17.7 3.5 0.0033 17.0 0.1 2.7 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KIR61193.1 - 0.0023 18.4 0.0 0.0063 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 KIR61193.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.5 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KIR61193.1 - 0.013 15.9 0.4 0.86 9.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KIR61193.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KIR61193.1 - 0.034 14.3 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KIR61193.1 - 0.039 14.0 0.0 2.6 8.0 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 KIR61193.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIR61193.1 - 0.059 13.8 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 KIR61193.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NTPase_1 PF03266.15 KIR61193.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 NTPase MCM PF00493.23 KIR61193.1 - 0.15 11.2 0.0 0.68 9.0 0.0 1.8 1 1 0 1 1 1 0 MCM P-loop domain NB-ARC PF00931.22 KIR61193.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 KIR61193.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KIR61193.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF948 PF06103.11 KIR61194.1 - 1.5e-24 86.0 10.0 4.9e-24 84.4 8.7 2.2 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 KIR61194.1 - 0.00073 19.6 3.6 0.00095 19.2 3.6 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KIR61194.1 - 0.028 14.4 0.5 0.028 14.4 0.5 1.8 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 KIR61194.1 - 0.085 13.3 6.4 0.12 12.8 4.9 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3181 PF11378.8 KIR61194.1 - 0.092 13.1 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) EzrA PF06160.12 KIR61194.1 - 0.1 10.8 2.3 0.15 10.2 1.7 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DASH_Duo1 PF08651.10 KIR61194.1 - 0.26 11.1 1.9 0.25 11.1 0.6 1.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 Glyco_transf_5 PF08323.11 KIR61195.1 - 0.18 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain tRNA-synt_2c PF01411.19 KIR61196.1 - 1.3e-184 614.8 0.0 1.5e-184 614.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KIR61196.1 - 5.3e-16 59.3 4.6 5.3e-16 59.3 4.6 2.1 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 KIR61196.1 - 1.2e-14 54.1 0.2 2.5e-14 53.1 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RuvX PF03652.15 KIR61197.1 - 1.5e-41 142.0 0.1 1.7e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Holliday junction resolvase YceG PF02618.16 KIR61198.1 - 1.4e-64 218.4 0.1 1.6e-64 218.1 0.1 1.0 1 0 0 1 1 1 1 YceG-like family Shikimate_dh_N PF08501.11 KIR61199.1 - 3.8e-22 78.3 0.0 7.8e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KIR61199.1 - 1.1e-09 37.8 0.7 2.1e-09 37.0 0.7 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 KIR61199.1 - 0.0028 18.2 0.1 0.0052 17.3 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KIR61199.1 - 0.0058 16.0 2.0 0.011 15.1 2.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 KIR61199.1 - 0.025 14.5 1.6 0.037 13.9 1.6 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIR61199.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDPD PF03009.17 KIR61200.1 - 2.4e-42 145.5 0.0 7.1e-42 143.9 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIR61200.1 - 8.7e-06 26.0 2.5 1e-05 25.8 0.2 2.5 3 1 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family BiPBP_C PF06832.12 KIR61200.1 - 0.0015 18.5 0.4 0.26 11.4 0.1 2.8 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family Big_7 PF17957.1 KIR61200.1 - 0.02 15.6 1.6 0.02 15.6 1.6 2.6 3 1 0 3 3 3 0 Bacterial Ig domain HTH_31 PF13560.6 KIR61201.1 - 0.00019 21.7 0.6 0.00019 21.7 0.6 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_35 PF13693.6 KIR61201.1 - 0.00027 20.9 0.1 0.0019 18.2 0.0 2.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 KIR61201.1 - 0.00074 19.6 0.0 0.0023 18.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR61201.1 - 0.00077 18.8 0.1 0.0022 17.3 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 KIR61201.1 - 0.00085 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR61201.1 - 0.004 16.9 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain YdaS_antitoxin PF15943.5 KIR61201.1 - 0.0041 16.9 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 KIR61201.1 - 0.0059 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 MerR family regulatory protein HTH_3 PF01381.22 KIR61201.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_38 PF13936.6 KIR61201.1 - 0.0072 16.1 0.2 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_36 PF13730.6 KIR61201.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61201.1 - 0.059 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Phage_CI_repr PF07022.13 KIR61201.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_26 PF13443.6 KIR61201.1 - 0.19 12.2 0.0 1.6 9.3 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MerR_1 PF13411.6 KIR61201.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_31 PF13560.6 KIR61202.1 - 1.6e-13 50.8 2.0 1.6e-13 50.8 2.0 4.8 4 2 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61202.1 - 9.4e-05 22.4 0.0 0.00075 19.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR61202.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 KIR61202.1 - 0.099 13.1 0.0 0.39 11.2 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Chorismate_synt PF01264.21 KIR61203.1 - 3.3e-117 390.9 0.8 3.7e-117 390.7 0.8 1.0 1 0 0 1 1 1 1 Chorismate synthase Caa3_CtaG PF09678.10 KIR61205.1 - 1.6e-52 178.3 26.4 2.1e-52 177.9 26.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF3040 PF11239.8 KIR61205.1 - 0.25 11.7 14.0 0.25 11.7 2.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF2243 PF10002.9 KIR61206.1 - 8.1e-50 168.6 13.0 9.3e-50 168.4 13.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DHQ_synthase PF01761.20 KIR61207.1 - 3.6e-88 295.1 0.0 4.4e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KIR61207.1 - 2.8e-08 33.8 5.9 4.6e-07 29.8 5.9 2.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KIR61207.1 - 4.6e-05 22.4 2.1 4.6e-05 22.4 2.1 2.6 3 1 0 3 3 3 1 Iron-containing alcohol dehydrogenase EFP_N PF08207.12 KIR61208.1 - 6.4e-28 96.6 0.4 3.3e-27 94.3 0.4 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 KIR61208.1 - 2.1e-26 91.4 2.1 4.7e-26 90.3 0.4 2.4 3 0 0 3 3 3 1 Elongation factor P, C-terminal EFP PF01132.20 KIR61208.1 - 1e-21 76.7 0.0 2.1e-21 75.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain NusB PF01029.18 KIR61209.1 - 6.8e-33 113.8 0.0 7.9e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 NusB family HTH_31 PF13560.6 KIR61210.1 - 9e-10 38.8 5.8 1.1e-08 35.3 1.8 2.5 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_3 PF01381.22 KIR61210.1 - 1e-09 38.3 0.1 1e-08 35.1 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix HTH_25 PF13413.6 KIR61210.1 - 0.33 10.9 3.0 0.8 9.6 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Pribosyltran PF00156.27 KIR61211.1 - 7.4e-25 87.3 1.0 8.7e-25 87.1 1.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIR61211.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KIR61211.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase OTCace_N PF02729.21 KIR61212.1 - 9.5e-43 145.8 0.1 1.3e-42 145.3 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KIR61212.1 - 9.8e-28 97.2 0.0 1.8e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Amidohydro_1 PF01979.20 KIR61213.1 - 4.6e-18 65.6 0.1 7e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family DHOase PF12890.7 KIR61213.1 - 2.4e-16 59.9 0.0 4.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Dihydro-orotase-like Amidohydro_3 PF07969.11 KIR61213.1 - 7.6e-05 22.4 10.0 0.0018 17.8 0.4 2.9 1 1 0 2 2 2 2 Amidohydrolase family CPSase_sm_chain PF00988.22 KIR61214.1 - 1.7e-51 173.3 0.1 4.3e-51 172.1 0.0 1.7 1 1 1 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIR61214.1 - 3.2e-35 121.6 0.0 5.3e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIR61214.1 - 1.8e-08 34.4 0.0 6.5e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase C26 CPSase_L_D2 PF02786.17 KIR61215.1 - 2.8e-102 340.7 0.0 3.6e-63 212.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KIR61215.1 - 9e-36 122.9 0.0 1.7e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KIR61215.1 - 2.3e-19 69.3 0.0 9.7e-19 67.4 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 KIR61215.1 - 3.8e-15 55.9 0.0 3.8e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIR61215.1 - 4e-11 42.8 0.0 6.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIR61215.1 - 9.6e-11 41.5 0.1 4.3e-06 26.5 0.1 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KIR61215.1 - 2.9e-05 24.2 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KIR61215.1 - 6e-05 22.7 0.0 0.021 14.4 0.0 3.0 2 2 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KIR61215.1 - 0.0004 20.0 0.0 0.93 9.0 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KIR61215.1 - 0.0017 17.9 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KIR61215.1 - 0.012 15.3 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Aminotran_3 PF00202.21 KIR61216.1 - 5.1e-116 387.7 0.0 6.2e-116 387.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III OMPdecase PF00215.24 KIR61217.1 - 2e-31 109.3 0.0 2.4e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribosomal_S13 PF00416.22 KIR61218.1 - 3.8e-05 24.1 0.4 5.6e-05 23.5 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S13/S18 HHH_5 PF14520.6 KIR61218.1 - 0.0041 17.7 1.2 0.013 16.1 0.6 2.0 2 1 0 2 2 2 1 Helix-hairpin-helix domain CDC73_N PF16050.5 KIR61218.1 - 0.0047 16.3 0.6 0.0047 16.3 0.6 1.0 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal GldM_N PF12081.8 KIR61218.1 - 0.025 14.7 0.2 0.027 14.6 0.2 1.1 1 0 0 1 1 1 0 GldM N-terminal domain TPR_14 PF13428.6 KIR61218.1 - 0.18 12.7 2.8 0.34 11.8 2.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FbpA PF05833.11 KIR61218.1 - 0.33 9.7 3.1 2.3 6.9 0.0 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Metal_resist PF13801.6 KIR61218.1 - 1.8 8.7 9.5 0.5 10.6 5.4 1.8 1 1 1 2 2 2 0 Heavy-metal resistance Guanylate_kin PF00625.21 KIR61219.1 - 2.1e-14 53.6 0.0 2.7e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase RNA_pol_Rpb6 PF01192.22 KIR61220.1 - 4.3e-13 49.0 0.1 5.9e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 DFP PF04127.15 KIR61221.1 - 8.4e-66 221.4 1.6 8.4e-66 221.4 1.6 1.9 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 KIR61221.1 - 2e-38 131.6 0.0 4.6e-38 130.4 0.0 1.6 2 0 0 2 2 2 1 Flavoprotein NAD_binding_7 PF13241.6 KIR61221.1 - 0.0058 17.0 1.0 3.1 8.3 0.6 3.8 2 2 0 2 2 2 1 Putative NAD(P)-binding S-AdoMet_synt_C PF02773.16 KIR61222.1 - 5.5e-67 224.0 0.0 8.4e-67 223.4 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KIR61222.1 - 4.4e-44 149.6 0.0 1.3e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KIR61222.1 - 1.3e-40 138.1 0.1 2.8e-40 137.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AAA_18 PF13238.6 KIR61223.1 - 3.3e-18 66.5 0.0 5.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 KIR61223.1 - 1.3e-10 41.7 0.3 2.6e-08 34.2 0.2 2.6 2 1 0 2 2 2 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KIR61223.1 - 2.8e-09 37.0 0.2 4e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Cytidylate kinase AAA_17 PF13207.6 KIR61223.1 - 6e-07 30.0 0.1 2.7e-06 27.8 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR61223.1 - 1.3e-05 25.4 0.4 3.3e-05 24.1 0.4 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KIR61223.1 - 0.00027 21.1 0.1 0.00044 20.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.12 KIR61223.1 - 0.0011 18.4 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin ADK PF00406.22 KIR61223.1 - 0.0017 18.4 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase ParBc PF02195.18 KIR61223.1 - 0.004 17.4 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain TsaE PF02367.17 KIR61223.1 - 0.0054 16.7 0.1 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KIR61223.1 - 0.13 12.0 0.0 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pep_deformylase PF01327.21 KIR61224.1 - 1.9e-39 134.8 0.0 2.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Formyl_trans_N PF00551.19 KIR61225.1 - 1.2e-34 119.7 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KIR61225.1 - 2.6e-19 69.3 0.0 4.3e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain LRV PF01816.17 KIR61225.1 - 2 9.0 8.0 15 6.3 0.2 3.9 3 0 0 3 3 3 0 Leucine rich repeat variant Methyltr_RsmB-F PF01189.17 KIR61226.1 - 1.2e-43 149.1 0.0 1.8e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 KIR61226.1 - 2.8e-25 89.1 0.0 4.3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 NusB family Methyltransf_11 PF08241.12 KIR61226.1 - 0.04 14.6 0.0 0.16 12.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KIR61226.1 - 0.056 13.1 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FtsJ PF01728.19 KIR61226.1 - 0.066 13.3 0.0 0.78 9.8 0.0 2.4 1 1 1 2 2 2 0 FtsJ-like methyltransferase Septum_form PF13845.6 KIR61227.1 - 1.9e-49 168.2 0.0 2.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Septum formation Ribul_P_3_epim PF00834.19 KIR61228.1 - 1.4e-74 249.7 0.0 1.7e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KIR61228.1 - 0.00085 19.0 0.2 0.0016 18.1 0.2 1.5 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 KIR61228.1 - 0.0017 17.9 0.1 0.12 11.9 0.1 2.1 1 1 0 2 2 2 2 Histidine biosynthesis protein QRPTase_C PF01729.19 KIR61228.1 - 0.011 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Response_reg PF00072.24 KIR61229.1 - 1.1e-29 102.8 0.1 1.6e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GGDEF PF00990.21 KIR61229.1 - 2.3e-11 43.7 0.0 1e-10 41.6 0.0 2.0 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain RibD_C PF01872.17 KIR61230.1 - 6.3e-50 169.8 0.4 8.3e-50 169.4 0.4 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 KIR61230.1 - 3e-16 59.1 0.0 5.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIR61230.1 - 5.7e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Lum_binding PF00677.17 KIR61231.1 - 8.1e-51 170.0 0.0 3.5e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain GBV-C_env PF12786.7 KIR61231.1 - 0.043 12.5 0.0 0.32 9.6 0.0 1.8 1 1 1 2 2 2 0 GB virus C genotype envelope NMN_transporter PF04973.12 KIR61232.1 - 4.1e-52 176.7 13.6 4.7e-52 176.5 13.6 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter NMO PF03060.15 KIR61232.1 - 0.16 11.3 0.1 0.21 10.9 0.1 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase DHBP_synthase PF00926.19 KIR61233.1 - 8.7e-88 292.9 0.1 1.2e-87 292.4 0.1 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 KIR61233.1 - 6.7e-71 237.2 0.0 1.3e-70 236.3 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II DMRL_synthase PF00885.19 KIR61234.1 - 1.1e-43 148.4 3.9 1.3e-43 148.2 3.9 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ABC_tran PF00005.27 KIR61235.1 - 3.4e-33 115.1 0.0 4.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR61235.1 - 1.5e-11 44.7 0.0 0.00012 22.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR61235.1 - 5.2e-07 29.3 0.0 0.00051 19.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR61235.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR61235.1 - 0.00017 21.9 0.1 0.0013 19.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61235.1 - 0.0012 19.3 0.9 0.0028 18.1 0.9 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIR61235.1 - 0.0038 17.0 0.1 0.072 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KIR61235.1 - 0.0074 16.5 0.1 0.081 13.2 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KIR61235.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 KIR61235.1 - 0.0087 16.2 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KIR61235.1 - 0.015 14.5 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KIR61235.1 - 0.015 15.8 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIR61235.1 - 0.018 14.6 0.9 0.18 11.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR61235.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KIR61235.1 - 0.032 13.9 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIR61235.1 - 0.055 13.5 0.1 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KIR61235.1 - 0.077 13.2 0.3 0.3 11.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KIR61235.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KIR61235.1 - 0.15 12.1 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIR61235.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase ABC_ATPase PF09818.9 KIR61235.1 - 0.16 10.7 0.0 8.1 5.1 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class G-alpha PF00503.20 KIR61235.1 - 0.3 10.2 0.0 0.49 9.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit BPD_transp_1 PF00528.22 KIR61236.1 - 3.7e-16 59.4 11.6 3.7e-16 59.4 11.6 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Tom5 PF10642.9 KIR61236.1 - 0.084 12.9 0.2 0.26 11.4 0.2 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Y_phosphatase2 PF03162.13 KIR61236.1 - 0.29 10.7 0.1 0.44 10.1 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family SBP_bac_3 PF00497.20 KIR61237.1 - 1.6e-39 135.6 0.4 2e-39 135.4 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KIR61237.1 - 0.00028 21.1 0.0 0.0019 18.4 0.0 2.1 2 0 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site PRA-PH PF01503.17 KIR61238.1 - 1.6e-06 28.5 0.9 2.3e-06 28.0 0.9 1.4 1 1 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase LPD34 PF18852.1 KIR61238.1 - 0.033 13.8 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 HisG PF01634.18 KIR61239.1 - 3.6e-42 144.1 0.0 4.8e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KIR61239.1 - 1e-26 92.9 0.0 1.7e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KIR61239.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like DMT_YdcZ PF04657.13 KIR61240.1 - 4.7e-36 124.1 45.7 1.3e-20 74.1 16.0 2.2 2 0 0 2 2 2 2 Putative inner membrane exporter, YdcZ bPH_6 PF10756.9 KIR61241.1 - 1.4e-20 73.1 6.2 2.7e-20 72.2 6.2 1.5 1 0 0 1 1 1 1 Bacterial PH domain DUF4190 PF13828.6 KIR61241.1 - 0.19 11.5 4.6 0.63 9.9 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) IF3_C PF00707.22 KIR61242.1 - 4.1e-33 113.2 0.1 7.1e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 KIR61242.1 - 2.9e-30 104.3 0.0 4.8e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 KIR61242.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Ribosomal_L35p PF01632.19 KIR61243.1 - 1.3e-22 80.1 9.3 1.4e-22 79.9 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 NPIP PF06409.11 KIR61243.1 - 0.057 12.5 2.9 0.065 12.3 2.9 1.0 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Ribosomal_L20 PF00453.18 KIR61244.1 - 1.2e-43 147.6 6.6 1.4e-43 147.4 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 SpoU_methylase PF00588.19 KIR61245.1 - 1.5e-33 116.0 0.0 2.1e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KIR61245.1 - 1.5e-10 41.2 0.0 2.1e-09 37.5 0.0 2.3 1 1 1 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding tRNA-synt_2d PF01409.20 KIR61246.1 - 3.7e-101 337.7 0.0 4.4e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 KIR61246.1 - 2.9e-16 59.1 0.1 5e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain B3_4 PF03483.17 KIR61247.1 - 8.2e-69 230.7 0.0 1.2e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 KIR61247.1 - 2e-59 200.6 0.0 2.9e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 KIR61247.1 - 3.6e-22 78.6 0.0 6.6e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 KIR61247.1 - 1.8e-18 66.4 0.0 3.8e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 KIR61247.1 - 1.1e-16 60.9 0.0 8.8e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase B5 domain HEAT_2 PF13646.6 KIR61248.1 - 1.2e-06 28.8 17.9 1.7e-05 25.1 1.2 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KIR61248.1 - 0.0042 17.2 2.7 9.8 6.7 0.1 4.2 3 0 0 3 3 3 2 HEAT repeat Sporozoite_P67 PF05642.11 KIR61248.1 - 8.5 4.3 5.2 13 3.7 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TetR_C_30 PF17939.1 KIR61249.1 - 2 8.6 7.2 1.3 9.3 0.2 3.1 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Semialdhyde_dh PF01118.24 KIR61250.1 - 4.1e-27 95.0 0.2 1.3e-26 93.4 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KIR61250.1 - 4.6e-16 59.4 0.1 9.1e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 KIR61250.1 - 0.0071 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ACP_syn_III_C PF08541.10 KIR61250.1 - 0.078 13.2 0.5 0.25 11.5 0.5 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2749 PF10907.8 KIR61250.1 - 0.71 10.1 3.4 3.4 7.9 3.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) ArgJ PF01960.18 KIR61251.1 - 8.3e-129 429.6 13.0 9.3e-129 429.4 13.0 1.0 1 0 0 1 1 1 1 ArgJ family AA_kinase PF00696.28 KIR61252.1 - 2.6e-48 164.7 0.4 3e-48 164.5 0.4 1.0 1 0 0 1 1 1 1 Amino acid kinase family Aminotran_3 PF00202.21 KIR61253.1 - 1.8e-104 349.7 0.0 2.2e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KIR61253.1 - 0.006 15.9 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIR61253.1 - 0.036 13.0 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V OTCace PF00185.24 KIR61254.1 - 8.6e-54 181.9 0.0 1.1e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KIR61254.1 - 8.4e-42 142.7 0.0 1.2e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Arg_repressor_C PF02863.18 KIR61255.1 - 1.4e-24 85.7 0.0 2.1e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain Arg_repressor PF01316.21 KIR61255.1 - 3.3e-22 78.0 0.0 4.8e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HTH_Tnp_Tc3_2 PF01498.18 KIR61255.1 - 0.12 12.6 0.1 0.27 11.5 0.0 1.6 2 0 0 2 2 2 0 Transposase Arginosuc_synth PF00764.19 KIR61256.1 - 2e-180 600.2 0.0 2.3e-180 600.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KIR61256.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIR61256.1 - 0.17 10.6 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Lyase_1 PF00206.20 KIR61257.1 - 8.3e-66 222.5 0.0 1.1e-65 222.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KIR61257.1 - 5.1e-21 75.2 0.6 5.1e-21 75.2 0.6 3.2 4 0 0 4 4 4 1 Argininosuccinate lyase C-terminal YjbR PF04237.13 KIR61258.1 - 3.4e-17 62.8 0.0 4.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 YjbR Pur_DNA_glyco PF02245.16 KIR61260.1 - 3.7e-64 215.4 0.0 4.2e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Cecropin PF00272.19 KIR61260.1 - 7 6.5 7.0 0.43 10.3 1.2 2.1 2 0 0 2 2 2 0 Cecropin family Sortilin-Vps10 PF15902.5 KIR61261.1 - 7.6e-13 48.0 0.0 0.00019 20.3 0.0 3.7 2 1 1 4 4 4 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 KIR61261.1 - 5.2e-12 43.9 16.5 0.55 10.4 0.9 7.6 8 0 0 8 8 8 6 BNR/Asp-box repeat BNR_2 PF13088.6 KIR61261.1 - 1.3e-07 31.2 0.3 0.0055 16.0 0.0 3.9 2 1 1 3 3 3 2 BNR repeat-like domain DUF4185 PF13810.6 KIR61261.1 - 7.2e-05 22.2 1.0 1.4 8.0 0.0 5.3 5 1 1 7 7 7 1 Domain of unknown function (DUF4185) BNR_3 PF13859.6 KIR61261.1 - 0.00031 20.2 0.1 12 5.0 0.0 4.6 5 0 0 5 5 5 2 BNR repeat-like domain BNR_6 PF15899.5 KIR61261.1 - 0.017 15.1 3.3 54 4.3 0.0 4.9 6 0 0 6 6 6 0 BNR-Asp box repeat ThiS PF02597.20 KIR61262.1 - 3.8e-12 46.7 0.1 4.3e-12 46.5 0.1 1.0 1 0 0 1 1 1 1 ThiS family Phage_NinH PF06322.11 KIR61262.1 - 0.094 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage NinH protein Sirohm_synth_M PF14824.6 KIR61262.1 - 0.18 11.3 0.4 0.44 10.0 0.4 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central FMN_red PF03358.15 KIR61263.1 - 2e-37 128.3 0.1 2.6e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIR61263.1 - 3.2e-07 30.2 0.0 5.9e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KIR61263.1 - 0.063 13.5 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain YhzD PF14120.6 KIR61263.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 YhzD-like protein Usp PF00582.26 KIR61264.1 - 7e-52 175.7 11.2 1.3e-26 93.8 0.1 2.0 2 0 0 2 2 2 2 Universal stress protein family FR47 PF08445.10 KIR61264.1 - 0.015 15.3 0.5 13 5.8 0.0 3.1 3 0 0 3 3 3 0 FR47-like protein Opi1 PF08618.10 KIR61264.1 - 0.11 11.8 0.2 0.18 11.0 0.0 1.4 2 0 0 2 2 2 0 Transcription factor Opi1 Usp PF00582.26 KIR61265.1 - 6.9e-48 162.7 9.9 1.2e-24 87.4 1.8 2.0 2 0 0 2 2 2 2 Universal stress protein family PGM_PMM_I PF02878.16 KIR61265.1 - 0.014 15.1 0.3 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I cNMP_binding PF00027.29 KIR61266.1 - 2.8e-08 33.7 0.0 3.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ADH_N PF08240.12 KIR61267.1 - 7.5e-32 109.5 2.1 9.8e-32 109.1 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR61267.1 - 7.7e-28 97.1 1.1 7.7e-28 97.1 1.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR61267.1 - 3e-10 41.3 1.4 4.8e-10 40.6 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding PF02629.19 KIR61267.1 - 0.0028 18.3 0.8 0.011 16.4 0.6 2.2 1 1 0 1 1 1 1 CoA binding domain Methyltransf_25 PF13649.6 KIR61267.1 - 0.023 15.4 0.8 0.049 14.3 0.2 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61267.1 - 0.035 14.8 0.8 0.25 12.0 0.8 2.2 1 1 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 KIR61267.1 - 0.17 11.2 4.4 0.28 10.4 4.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.6 KIR61267.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PEP-utilizers_C PF02896.18 KIR61268.1 - 7.5e-81 271.5 0.0 1.1e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 KIR61268.1 - 8.7e-53 179.7 0.0 3.9e-29 102.0 0.0 3.2 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 KIR61268.1 - 3.9e-25 87.4 1.4 8.2e-25 86.3 1.4 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Imp-YgjV PF10688.9 KIR61269.1 - 0.00028 20.7 5.8 0.00035 20.4 5.8 1.1 1 0 0 1 1 1 1 Bacterial inner membrane protein DUF21 PF01595.20 KIR61270.1 - 3.6e-42 144.0 1.6 5.5e-42 143.5 1.6 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 KIR61270.1 - 2.9e-15 56.1 0.0 2.9e-15 56.1 0.0 2.2 3 0 0 3 3 3 1 Transporter associated domain CBS PF00571.28 KIR61270.1 - 2.1e-14 53.7 2.1 1.7e-08 34.8 0.2 2.5 2 0 0 2 2 2 2 CBS domain Colicin_V PF02674.16 KIR61270.1 - 0.0091 16.0 3.6 0.019 14.9 3.6 1.5 1 0 0 1 1 1 1 Colicin V production protein Saf_2TM PF18303.1 KIR61270.1 - 0.19 11.3 1.2 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PRC PF05239.16 KIR61271.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 PRC-barrel domain PRC PF05239.16 KIR61272.1 - 5.5e-05 23.2 0.9 0.00012 22.1 0.9 1.7 1 1 0 1 1 1 1 PRC-barrel domain DUF2171 PF09939.9 KIR61272.1 - 0.0043 17.3 1.1 0.81 10.0 0.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2171) Nramp PF01566.18 KIR61273.1 - 8.6e-48 163.1 29.0 8.6e-48 163.1 29.0 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein 4HBT PF03061.22 KIR61274.1 - 3.4e-16 59.3 0.5 5e-16 58.8 0.5 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KIR61274.1 - 1.4e-07 31.7 0.0 1.8e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KIR61274.1 - 5.4e-07 30.1 0.9 6.1e-07 29.9 0.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Thi4 PF01946.17 KIR61274.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Thi4 family Hydrolase_6 PF13344.6 KIR61275.1 - 1.8e-23 82.6 0.0 6.2e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR61275.1 - 1.6e-18 66.5 0.2 5.8e-18 64.7 0.1 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like GNAT_like PF18407.1 KIR61275.1 - 9.8e-11 41.8 12.4 9.8e-11 41.8 12.4 2.9 2 0 0 2 2 2 1 GCN5-related N-acetyltransferase like domain Hydrolase PF00702.26 KIR61275.1 - 3.6e-10 40.5 2.3 2.2e-09 37.9 2.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIR61275.1 - 1.5e-05 25.2 0.1 0.0023 18.1 0.0 2.9 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase SCP2 PF02036.17 KIR61276.1 - 3.3e-10 40.3 0.3 3.9e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIR61276.1 - 1.8e-07 31.5 0.2 2.1e-07 31.3 0.2 1.0 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Phasin PF05597.11 KIR61277.1 - 6.7e-05 22.9 1.0 6.7e-05 22.9 1.0 1.6 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) HC2 PF07382.11 KIR61277.1 - 0.00024 21.2 15.6 0.00024 21.2 15.6 1.7 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 PHA_synth_III_E PF09712.10 KIR61277.1 - 0.00049 19.3 0.5 0.0023 17.1 0.2 1.9 1 1 1 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Pox_A_type_inc PF04508.12 KIR61277.1 - 0.0094 15.8 0.2 0.015 15.1 0.2 1.3 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat 3-PAP PF12578.8 KIR61277.1 - 0.051 13.3 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Myotubularin-associated protein HalX PF08663.10 KIR61277.1 - 0.1 13.0 0.3 0.1 13.0 0.3 1.9 2 0 0 2 2 2 0 HalX domain FtsJ PF01728.19 KIR61279.1 - 3e-18 66.5 0.0 3.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 KIR61279.1 - 3.2e-07 29.9 0.1 8e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 S4 domain Methyltransf_25 PF13649.6 KIR61279.1 - 0.039 14.7 0.1 0.13 13.0 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain SMC_N PF02463.19 KIR61280.1 - 4e-12 46.1 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR61280.1 - 1.3e-07 32.4 0.0 1.7e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIR61280.1 - 0.0042 16.9 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIR61280.1 - 0.0098 16.2 0.0 0.14 12.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR61280.1 - 0.15 11.8 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FTA4 PF13093.6 KIR61280.1 - 0.56 10.1 1.8 0.88 9.4 0.7 1.8 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MctB PF11382.8 KIR61281.1 - 2.1e-86 290.4 16.4 2.4e-86 290.2 16.4 1.0 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB bZIP_1 PF00170.21 KIR61281.1 - 0.035 14.2 0.9 0.061 13.4 0.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor TP_methylase PF00590.20 KIR61281.1 - 0.043 13.7 1.4 1.2 9.0 0.4 2.6 2 1 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases HAP1_N PF04849.13 KIR61281.1 - 0.046 12.9 0.2 0.072 12.3 0.2 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_2 PF07716.15 KIR61281.1 - 0.11 12.6 0.7 0.19 11.8 0.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF4148 PF13663.6 KIR61281.1 - 0.56 10.4 2.7 1.2 9.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) MurJ PF03023.14 KIR61282.1 - 1.4e-44 152.5 22.9 2e-44 151.9 22.9 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ MatE PF01554.18 KIR61282.1 - 1.2e-06 28.3 11.6 1.2e-06 28.3 11.6 3.7 3 0 0 3 3 3 2 MatE CTP_synth_N PF06418.14 KIR61283.1 - 5.5e-120 399.6 0.0 6.8e-120 399.3 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KIR61283.1 - 2.1e-46 158.1 0.0 3e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIR61283.1 - 1.9e-07 31.0 0.1 2.4e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KIR61283.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Phage_Cox PF10743.9 KIR61283.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Regulatory phage protein cox NUDIX PF00293.28 KIR61284.1 - 3.9e-16 59.3 0.3 6e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain TM2 PF05154.16 KIR61285.1 - 3.9e-17 62.3 5.3 5.2e-17 61.9 5.3 1.1 1 0 0 1 1 1 1 TM2 domain AlaDh_PNT_C PF01262.21 KIR61286.1 - 3.8e-80 268.2 0.3 5.2e-80 267.8 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KIR61286.1 - 4.6e-47 159.7 0.2 8.9e-47 158.8 0.1 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 KIR61286.1 - 0.00041 19.7 0.1 0.00086 18.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIR61286.1 - 0.0014 17.4 0.7 0.0021 16.8 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_2 PF03446.15 KIR61286.1 - 0.002 18.3 0.9 0.0073 16.5 0.2 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KIR61286.1 - 0.0032 16.8 0.5 0.0068 15.7 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR61286.1 - 0.0072 16.9 0.1 0.047 14.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR61286.1 - 0.0089 15.2 1.0 0.017 14.2 0.7 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 KIR61286.1 - 0.036 14.1 0.2 0.063 13.3 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KIR61286.1 - 0.078 13.2 0.6 0.078 13.2 0.6 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KIR61286.1 - 0.13 12.1 1.1 0.4 10.6 1.1 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_31 PF13614.6 KIR61287.1 - 1e-61 208.0 0.0 1.3e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIR61287.1 - 1.3e-24 86.7 0.2 3.1e-23 82.2 0.2 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KIR61287.1 - 9.9e-12 44.8 0.0 6.4e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KIR61287.1 - 3.7e-11 43.0 0.0 5.7e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 KIR61287.1 - 2.2e-10 40.3 0.3 1.3e-05 24.7 0.1 2.2 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 KIR61287.1 - 6e-09 35.7 0.2 1.5e-08 34.4 0.2 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 KIR61287.1 - 3.3e-08 33.1 0.1 8e-08 31.8 0.1 1.8 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 KIR61287.1 - 0.00066 19.1 0.1 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 VirC1 protein DUF1611 PF07755.11 KIR61287.1 - 0.0024 17.2 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain SRP54 PF00448.22 KIR61287.1 - 0.02 14.5 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 KIR61287.1 - 0.027 13.4 0.4 0.06 12.3 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FTHFS PF01268.19 KIR61287.1 - 0.056 11.6 0.0 0.094 10.9 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase CLP1_P PF16575.5 KIR61287.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SMC_ScpB PF04079.16 KIR61288.1 - 1.8e-54 183.7 0.0 2.2e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB PseudoU_synth_2 PF00849.22 KIR61289.1 - 1.4e-21 77.2 0.0 2.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KIR61289.1 - 1.1e-10 41.1 0.5 3.1e-10 39.6 0.5 1.9 1 1 0 1 1 1 1 S4 domain Cytidylate_kin PF02224.18 KIR61290.1 - 4.8e-67 225.8 4.5 5.4e-67 225.6 4.5 1.0 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 KIR61290.1 - 1.8e-08 35.0 0.0 4e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 KIR61290.1 - 2.9e-06 27.5 0.9 1.8e-05 25.0 0.9 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family SKI PF01202.22 KIR61290.1 - 3e-05 24.2 0.5 0.013 15.7 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.6 KIR61290.1 - 4.7e-05 23.6 3.8 0.00018 21.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 KIR61290.1 - 0.00046 20.0 0.3 0.024 14.4 0.1 2.7 1 1 2 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 KIR61290.1 - 0.00076 19.9 0.2 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIR61290.1 - 0.0031 17.8 0.1 0.0073 16.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR61290.1 - 0.0034 17.8 0.4 0.0034 17.8 0.4 2.1 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIR61290.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KIR61290.1 - 0.017 15.1 0.1 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ADK PF00406.22 KIR61290.1 - 0.019 15.0 0.0 0.041 14.0 0.0 1.5 2 0 0 2 2 2 0 Adenylate kinase CbiA PF01656.23 KIR61290.1 - 0.076 13.1 0.1 0.2 11.7 0.1 1.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KIR61290.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ParA PF10609.9 KIR61290.1 - 0.091 12.2 0.3 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase ABC_tran PF00005.27 KIR61290.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.6 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 KIR61290.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KIR61290.1 - 0.24 11.3 0.0 0.37 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KIR61291.1 - 1.1e-49 167.2 0.1 2.7e-25 88.7 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIR61291.1 - 1.9e-24 86.0 0.0 2.6e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 KIR61291.1 - 3e-24 85.1 0.0 1.4e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 KIR61291.1 - 7.9e-16 58.2 0.0 5e-06 26.2 0.3 4.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIR61291.1 - 4.2e-12 46.3 1.1 0.034 14.1 0.0 4.0 3 1 0 3 3 3 3 RsgA GTPase Dynamin_N PF00350.23 KIR61291.1 - 5.2e-12 46.1 0.3 0.0079 16.3 0.0 4.1 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 KIR61291.1 - 1.3e-11 44.2 0.0 1.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 KIR61291.1 - 5.2e-09 36.4 0.1 0.0066 16.7 0.0 3.2 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIR61291.1 - 1.1e-08 34.9 0.0 0.0012 18.4 0.0 2.7 2 1 0 2 2 2 2 Ras family AAA_16 PF13191.6 KIR61291.1 - 4.1e-07 30.5 0.6 0.0064 16.9 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 KIR61291.1 - 6e-06 26.8 0.0 0.12 12.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter TniB PF05621.11 KIR61291.1 - 3.7e-05 23.2 0.0 0.066 12.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein PduV-EutP PF10662.9 KIR61291.1 - 5.8e-05 22.9 0.0 0.019 14.7 0.0 3.1 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KIR61291.1 - 0.00021 20.8 0.0 0.95 8.9 0.0 2.9 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit cobW PF02492.19 KIR61291.1 - 0.00031 20.4 0.1 11 5.6 0.0 3.9 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KIR61291.1 - 0.00055 19.0 5.3 0.43 9.5 0.0 3.6 4 1 0 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KIR61291.1 - 0.0007 19.4 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KIR61291.1 - 0.0024 17.8 0.0 0.1 12.5 0.0 2.5 2 1 0 2 2 2 1 NTPase Arf PF00025.21 KIR61291.1 - 0.0025 17.3 0.1 4.4 6.7 0.0 3.1 2 2 0 2 2 2 2 ADP-ribosylation factor family AAA_33 PF13671.6 KIR61291.1 - 0.0027 17.9 0.2 0.036 14.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIR61291.1 - 0.0059 16.5 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIR61291.1 - 0.011 16.0 0.0 3.8 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain GBP PF02263.19 KIR61291.1 - 0.021 14.1 0.2 0.91 8.7 0.0 2.7 3 1 0 3 3 3 0 Guanylate-binding protein, N-terminal domain RNA_helicase PF00910.22 KIR61291.1 - 0.032 14.6 0.0 3.9 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MCM PF00493.23 KIR61291.1 - 0.046 12.8 0.0 3 6.9 0.0 2.8 3 0 0 3 3 3 0 MCM P-loop domain AAA_29 PF13555.6 KIR61291.1 - 0.078 12.7 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KIR61291.1 - 0.11 12.8 0.0 17 5.6 0.0 2.9 2 2 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIR61291.1 - 0.13 11.5 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 KIR61291.1 - 0.16 11.7 0.0 38 3.9 0.0 3.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 KIR61291.1 - 0.19 11.8 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 KIR61291.1 - 0.19 12.3 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NOG1 PF06858.14 KIR61291.1 - 1.1 9.0 3.0 14 5.5 2.1 2.9 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) rve PF00665.26 KIR61292.1 - 1.7e-22 79.9 0.0 3.7e-22 78.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 KIR61292.1 - 4e-18 65.3 3.7 1.6e-17 63.3 1.8 2.4 2 0 0 2 2 2 1 HTH-like domain rve_3 PF13683.6 KIR61292.1 - 2.9e-10 39.7 0.0 5.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 KIR61292.1 - 3.4e-09 36.7 0.1 5.7e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain HEAT_2 PF13646.6 KIR61293.1 - 2.2e-07 31.2 36.9 0.00038 20.8 4.2 6.7 4 3 2 6 6 6 3 HEAT repeats HEAT PF02985.22 KIR61293.1 - 0.001 19.2 13.1 0.28 11.5 0.4 5.5 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 KIR61293.1 - 0.23 11.6 3.4 28 4.9 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2755 PF10954.8 KIR61296.1 - 0.076 12.9 0.1 0.086 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) CcmD PF04995.14 KIR61296.1 - 0.08 13.0 1.0 0.08 13.0 1.0 2.8 3 2 0 3 3 3 0 Heme exporter protein D (CcmD) YrhK PF14145.6 KIR61296.1 - 0.097 12.6 2.0 0.13 12.2 2.0 1.2 1 0 0 1 1 1 0 YrhK-like protein FixQ PF05545.11 KIR61296.1 - 0.18 11.8 2.4 3.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DDE_Tnp_4 PF13359.6 KIR61298.1 - 3.3e-31 108.1 0.0 4.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR61298.1 - 1e-12 47.6 0.0 3.3e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR61298.1 - 2.9e-11 43.4 1.2 2.9e-11 43.4 1.2 2.1 2 1 0 2 2 2 1 Transposase DDE domain CobU PF02283.16 KIR61298.1 - 0.058 13.0 0.2 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase LRV PF01816.17 KIR61300.1 - 3.3e-11 42.8 115.6 0.00013 22.1 1.7 14.6 13 3 2 15 15 15 8 Leucine rich repeat variant HEAT PF02985.22 KIR61300.1 - 1.9e-08 33.8 20.6 0.92 9.9 0.1 10.1 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.6 KIR61300.1 - 3.6e-05 24.1 28.8 0.045 14.1 1.2 8.3 6 4 0 6 6 6 4 HEAT repeats HTH_15 PF12324.8 KIR61300.1 - 0.35 10.9 3.5 9.2 6.3 0.0 3.9 5 0 0 5 5 5 0 Helix-turn-helix domain of alkylmercury lyase HEAT_EZ PF13513.6 KIR61300.1 - 6.7 7.3 27.3 2.1 8.9 0.0 8.0 7 2 1 8 8 8 0 HEAT-like repeat DUF416 PF04222.12 KIR61302.1 - 1.2e-15 57.4 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF416) PrgI PF12666.7 KIR61303.1 - 1.5e-13 51.3 1.7 2.7e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 PrgI family protein TrbL PF04610.14 KIR61304.1 - 0.61 9.8 25.8 0.12 12.1 21.1 2.2 1 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein RhodobacterPufX PF11511.8 KIR61304.1 - 5.2 6.8 10.4 2 8.1 5.7 2.7 2 0 0 2 2 2 0 Intrinsic membrane protein PufX TrbC PF04956.13 KIR61305.1 - 5.9e-05 23.2 4.4 7.4e-05 22.9 4.4 1.2 1 0 0 1 1 1 1 TrbC/VIRB2 family SseC PF04888.12 KIR61305.1 - 0.017 14.7 2.2 0.019 14.6 2.2 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Sdh_cyt PF01127.22 KIR61305.1 - 0.017 15.1 0.4 0.022 14.8 0.4 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RNase_T PF00929.24 KIR61306.1 - 3.3e-22 79.8 0.0 4.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF2510 PF10708.9 KIR61306.1 - 4.7e-05 23.1 14.6 0.00032 20.4 14.6 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2510) TPR_9 PF13371.6 KIR61306.1 - 0.089 13.0 3.9 0.062 13.5 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CdiA_C PF18451.1 KIR61308.1 - 8.7e-17 61.1 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Contact-dependent growth inhibition CdiA C-terminal domain DUF1176 PF06674.11 KIR61309.1 - 0.43 10.0 8.4 0.46 9.9 7.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1176) TrbI PF03743.14 KIR61309.1 - 0.79 9.5 9.0 1.3 8.8 9.0 1.7 1 1 0 1 1 1 0 Bacterial conjugation TrbI-like protein N6_N4_Mtase PF01555.18 KIR61310.1 - 3e-18 66.4 0.0 1.2e-13 51.3 0.0 2.1 2 0 0 2 2 2 2 DNA methylase UPF0020 PF01170.18 KIR61310.1 - 3.4e-07 30.2 0.0 4.8e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KIR61310.1 - 0.0012 19.4 0.1 1.2 9.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61310.1 - 0.0042 17.8 0.1 0.067 13.9 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIR61310.1 - 0.056 12.8 0.1 0.079 12.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2883 PF11097.8 KIR61315.1 - 0.14 12.2 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Exo_endo_phos PF03372.23 KIR61318.1 - 0.00019 21.1 4.6 0.00033 20.2 4.6 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HA PF03457.14 KIR61319.1 - 2.5e-08 34.1 0.1 4e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Helicase associated domain DUF3670 PF12419.8 KIR61319.1 - 0.058 13.3 0.3 0.068 13.0 0.3 1.2 1 1 0 1 1 1 0 SNF2 Helicase protein HA PF03457.14 KIR61320.1 - 3.8e-36 123.2 5.7 4e-16 59.1 0.1 3.6 4 0 0 4 4 4 3 Helicase associated domain Helicase_C PF00271.31 KIR61320.1 - 3.8e-05 24.0 0.0 6.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR61321.1 - 1.1e-12 48.3 0.0 3.3e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIR61321.1 - 1.1e-06 28.5 0.0 4.4e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIR61321.1 - 0.012 15.3 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 KIR61321.1 - 0.019 15.2 0.0 0.29 11.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain MipZ PF09140.11 KIR61321.1 - 0.077 12.3 0.5 0.17 11.2 0.1 1.7 2 0 0 2 2 2 0 ATPase MipZ GPP34 PF05719.11 KIR61322.1 - 4.2e-32 111.9 6.9 5.2e-32 111.6 6.9 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) FmdA_AmdA PF03069.15 KIR61323.1 - 1.8e-29 102.8 0.1 6.7e-18 64.7 0.3 2.3 1 1 1 2 2 2 2 Acetamidase/Formamidase family AA_permease_2 PF13520.6 KIR61324.1 - 1.1e-39 136.5 41.8 1.4e-39 136.1 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIR61324.1 - 2.2e-31 109.0 36.9 3.1e-31 108.5 36.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF397 PF04149.12 KIR61325.1 - 3.1e-19 68.8 1.2 3.6e-19 68.6 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) tRNA-synt_1 PF00133.22 KIR61326.1 - 0.0054 15.0 0.0 0.54 8.4 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.7 KIR61326.1 - 0.19 11.8 0.3 0.41 10.7 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon GFO_IDH_MocA PF01408.22 KIR61327.1 - 9.5e-11 42.6 0.1 1.7e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DnaB_bind PF10410.9 KIR61330.1 - 0.021 15.0 0.9 0.087 13.0 0.2 2.0 1 1 1 2 2 2 0 DnaB-helicase binding domain of primase ANAPC5 PF12862.7 KIR61330.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 adh_short PF00106.25 KIR61331.1 - 4.6e-49 166.5 0.3 5.7e-49 166.2 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR61331.1 - 7.9e-45 153.2 0.4 9.7e-45 152.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR61331.1 - 6.9e-10 39.1 0.8 9.5e-10 38.7 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR61331.1 - 1.1e-06 28.3 0.1 2.3e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR61331.1 - 2.9e-05 24.0 0.5 4.1e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding EccE PF11203.8 KIR61331.1 - 0.0067 16.7 1.5 3.2 8.2 0.1 2.4 2 0 0 2 2 2 2 Putative type VII ESX secretion system translocon, EccE RmlD_sub_bind PF04321.17 KIR61331.1 - 0.011 14.9 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PLDc_2 PF13091.6 KIR61332.1 - 5e-10 39.4 0.0 1.4e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.22 KIR61332.1 - 0.0057 16.8 0.1 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 Phospholipase D Active site motif Helicase_C PF00271.31 KIR61333.1 - 4.5e-08 33.4 0.0 8.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyoxalase_4 PF13669.6 KIR61334.1 - 1.7e-12 47.6 0.0 2.5e-12 47.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KIR61334.1 - 2.1e-12 47.3 0.0 3.5e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KIR61334.1 - 2.3e-05 24.6 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KIR61334.1 - 3.6e-05 24.5 0.0 5.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KIR61334.1 - 0.21 11.5 0.0 4.8 7.1 0.0 2.6 2 1 0 2 2 2 0 Glyoxalase-like domain Cu-oxidase_3 PF07732.15 KIR61335.1 - 5.8e-35 119.9 1.1 1.1e-31 109.3 0.1 2.9 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIR61335.1 - 9.7e-25 86.9 4.1 4.8e-22 78.2 0.1 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KIR61335.1 - 8.3e-06 26.0 0.0 0.00068 19.8 0.0 2.6 2 0 0 2 2 2 1 Multicopper oxidase ADH_zinc_N PF00107.26 KIR61336.1 - 1.5e-20 73.5 0.0 3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR61336.1 - 1.3e-18 68.3 0.1 4.5e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR61336.1 - 6.7e-06 26.0 0.0 2.7e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KIR61336.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_16 PF13191.6 KIR61338.1 - 1.3e-18 67.9 1.0 1.3e-18 67.9 1.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain GerE PF00196.19 KIR61338.1 - 8.9e-16 57.2 0.3 1.9e-15 56.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 KIR61338.1 - 0.00011 21.9 0.1 0.00011 21.9 0.1 3.3 4 1 1 5 5 5 1 Homeodomain-like domain AAA_22 PF13401.6 KIR61338.1 - 0.00016 22.0 0.0 0.00086 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain HTH_28 PF13518.6 KIR61338.1 - 0.00069 19.7 0.1 0.0091 16.1 0.1 3.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 KIR61338.1 - 0.0026 17.5 0.0 0.038 13.8 0.0 2.8 2 0 0 2 2 2 1 HTH DNA binding domain DAP3 PF10236.9 KIR61338.1 - 0.0069 15.6 0.3 0.042 13.0 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 HTH_30 PF13556.6 KIR61338.1 - 0.022 14.5 0.2 0.12 12.2 0.2 2.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF2791 PF10923.8 KIR61338.1 - 0.029 13.2 0.1 0.081 11.8 0.0 1.7 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 KIR61338.1 - 0.036 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain HTH_24 PF13412.6 KIR61338.1 - 0.1 12.2 0.1 3.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TPR_21 PF09976.9 KIR61338.1 - 1.1 8.9 5.8 0.14 11.8 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 KIR61338.1 - 9.6 6.2 9.0 39 4.3 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat SnoaL PF07366.12 KIR61339.1 - 4.9e-20 71.6 0.0 5.8e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIR61339.1 - 1.1e-16 61.3 0.5 1.4e-16 61.0 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain FAD_binding_3 PF01494.19 KIR61340.1 - 3.7e-15 56.0 9.0 7.3e-14 51.8 8.9 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIR61340.1 - 0.00014 22.0 0.6 0.00014 22.0 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR61340.1 - 0.0015 17.7 0.9 0.0032 16.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIR61340.1 - 0.0024 17.0 0.1 0.56 9.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIR61340.1 - 0.0061 15.8 0.8 0.026 13.8 0.9 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIR61340.1 - 0.02 14.8 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KIR61340.1 - 0.035 13.7 8.2 0.031 13.8 2.2 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase AbfB PF05270.13 KIR61341.1 - 1.9e-47 160.8 2.2 4.2e-44 149.9 1.7 2.4 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) domain YpM PF09144.10 KIR61341.1 - 0.01 16.0 0.1 0.22 11.7 0.0 2.5 2 0 0 2 2 2 0 Yersinia pseudo-tuberculosis mitogen Alpha_L_fucos PF01120.17 KIR61342.1 - 1.5e-85 287.7 7.5 2e-85 287.3 7.5 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase RicinB_lectin_2 PF14200.6 KIR61342.1 - 8e-32 109.8 22.8 4.6e-16 59.3 3.0 3.8 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR61342.1 - 7.4e-11 42.4 0.3 1.3e-10 41.7 0.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Fucosidase_C PF16757.5 KIR61342.1 - 8.6e-05 23.0 0.0 0.00081 19.9 0.0 2.3 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain ABC_tran PF00005.27 KIR61343.1 - 1.7e-35 122.5 0.0 2.5e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR61343.1 - 1.2e-05 25.3 0.3 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 KIR61343.1 - 4.7e-05 23.5 0.8 9.6e-05 22.5 0.2 2.0 2 0 0 2 2 1 1 TOBE domain RsgA_GTPase PF03193.16 KIR61343.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIR61343.1 - 0.0033 17.8 0.4 0.0076 16.6 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIR61343.1 - 0.0046 16.7 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR61343.1 - 0.0085 15.6 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIR61343.1 - 0.0095 15.5 0.1 0.028 14.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KIR61343.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain CysA_C_terminal PF17850.1 KIR61343.1 - 0.016 15.8 0.5 0.086 13.4 0.1 2.6 2 0 0 2 2 2 0 CysA C-terminal regulatory domain AAA_23 PF13476.6 KIR61343.1 - 0.051 14.1 0.0 0.077 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR61343.1 - 0.077 12.4 0.0 0.22 10.9 0.0 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIR61343.1 - 0.081 13.2 0.3 0.18 12.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KIR61343.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIR61343.1 - 0.29 11.6 0.0 0.46 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase BPD_transp_1 PF00528.22 KIR61344.1 - 1.7e-12 47.5 13.6 1.7e-12 47.5 13.6 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR61345.1 - 1.3e-12 47.9 13.9 1.3e-12 47.9 13.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PmoA PF14100.6 KIR61346.1 - 4.1e-76 256.1 1.8 4.6e-76 255.9 1.8 1.0 1 0 0 1 1 1 1 Methane oxygenase PmoA CBM_6 PF03422.15 KIR61347.1 - 0.0017 18.6 7.8 0.0033 17.7 0.1 3.8 3 1 0 4 4 4 1 Carbohydrate binding module (family 6) Glyco_hydro_39 PF01229.17 KIR61347.1 - 0.06 11.9 0.1 0.09 11.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 DUF3502 PF12010.8 KIR61348.1 - 8.4e-28 97.6 0.2 2.2e-27 96.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3502) SBP_bac_1 PF01547.25 KIR61348.1 - 0.034 14.1 14.2 0.025 14.5 9.3 2.5 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein Abhydrolase_6 PF12697.7 KIR61349.1 - 2.5e-24 87.1 22.4 2.9e-24 86.9 22.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR61349.1 - 8.3e-22 78.1 0.3 3.4e-20 72.8 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR61349.1 - 1.5e-10 40.8 0.1 2.3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIR61349.1 - 3e-06 26.2 0.0 3.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 KIR61349.1 - 0.0029 16.6 0.1 0.0044 16.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF3530 PF12048.8 KIR61349.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Chlorophyllase PF07224.11 KIR61349.1 - 0.24 10.4 0.1 0.36 9.8 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase ThuA PF06283.11 KIR61350.1 - 1.2e-72 244.5 0.1 1.4e-72 244.3 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation Glyco_hydro_127 PF07944.12 KIR61351.1 - 1.6e-108 363.4 0.0 1.4e-96 324.1 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Laminin_G_3 PF13385.6 KIR61351.1 - 9.5e-32 110.3 0.9 2.2e-31 109.1 0.9 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Melibiase PF02065.18 KIR61352.1 - 8.8e-113 376.8 0.0 1.1e-112 376.4 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KIR61352.1 - 2e-42 145.5 0.0 2.7e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KIR61352.1 - 7.3e-07 29.6 0.0 2.9e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 36 C-terminal domain Melibiase_2 PF16499.5 KIR61352.1 - 0.00011 21.4 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Glyco_hydro_31 PF01055.26 KIR61352.1 - 0.0052 16.0 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL10 PF02638.15 KIR61352.1 - 0.24 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 2-Hacid_dh_C PF02826.19 KIR61353.1 - 2.8e-46 157.1 0.0 4.3e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIR61353.1 - 2.6e-13 49.8 0.0 3.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIR61353.1 - 0.0018 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase He_PIG PF05345.12 KIR61354.1 - 5.2e-08 32.9 0.1 5.2e-08 32.9 0.1 3.5 3 0 0 3 3 3 1 Putative Ig domain F5_F8_type_C PF00754.25 KIR61354.1 - 5.9e-07 29.7 7.5 0.00095 19.3 0.2 3.9 4 0 0 4 4 4 2 F5/8 type C domain BiPBP_C PF06832.12 KIR61354.1 - 0.0051 16.8 0.1 0.12 12.4 0.0 3.1 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Alginate_lyase PF05426.12 KIR61354.1 - 0.15 11.6 2.5 0.33 10.5 2.5 1.6 1 0 0 1 1 1 0 Alginate lyase Alpha-L-AF_C PF06964.12 KIR61355.1 - 1.2e-42 145.9 0.0 1.8e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KIR61355.1 - 0.047 13.6 0.0 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 Glycoside hydrolase family 44 DUF2721 PF11026.8 KIR61356.1 - 0.075 12.9 0.5 0.075 12.9 0.5 2.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) SieB PF14163.6 KIR61356.1 - 0.18 11.3 0.5 0.49 9.9 0.5 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF3533 PF12051.8 KIR61356.1 - 6.2 5.6 7.5 0.97 8.3 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) BPD_transp_1 PF00528.22 KIR61357.1 - 1.6e-14 54.1 14.4 1.6e-14 54.1 14.4 1.8 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 KIR61358.1 - 2.8e-12 47.2 15.1 3.9e-12 46.7 15.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Peripla_BP_3 PF13377.6 KIR61359.1 - 8.6e-33 114.0 1.8 2.2e-31 109.4 0.2 2.3 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR61359.1 - 2.1e-18 66.7 0.0 2.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR61359.1 - 1.9e-07 30.8 0.0 3.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR61359.1 - 6e-05 22.7 0.0 0.00035 20.2 0.0 2.1 2 1 0 2 2 2 1 Periplasmic binding protein domain MutL PF13941.6 KIR61359.1 - 0.0073 14.9 1.4 0.0098 14.5 1.4 1.2 1 0 0 1 1 1 1 MutL protein DDE_3 PF13358.6 KIR61360.1 - 5.3e-21 74.9 0.1 8.4e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KIR61360.1 - 1.6e-11 44.6 11.0 2.2e-11 44.2 1.3 3.6 4 0 0 4 4 3 1 Homeodomain-like domain HTH_29 PF13551.6 KIR61360.1 - 1.8e-10 40.7 7.4 1.7e-09 37.6 0.3 4.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_28 PF13518.6 KIR61360.1 - 1.2e-07 31.7 2.1 2.8e-05 24.2 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR61360.1 - 1.3e-07 31.2 4.6 1.5e-05 24.6 0.2 3.5 3 1 1 4 4 4 2 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 KIR61360.1 - 3.8e-06 27.3 2.1 2.4e-05 24.8 0.5 2.6 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 HTH_50 PF18024.1 KIR61360.1 - 9.9e-05 21.9 0.0 0.0032 17.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61360.1 - 0.00077 19.2 0.1 0.04 13.7 0.1 3.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_Tnp_1 PF01527.20 KIR61360.1 - 0.0018 18.5 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KIR61360.1 - 0.0041 16.8 0.5 2.9 7.7 0.1 3.2 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_6 PF01418.17 KIR61360.1 - 0.029 14.3 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family YdaS_antitoxin PF15943.5 KIR61360.1 - 0.079 12.8 0.1 6.4 6.7 0.0 2.8 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KIR61360.1 - 0.079 13.0 0.0 5.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix HTH_26 PF13443.6 KIR61360.1 - 0.092 13.2 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain KORA PF16509.5 KIR61360.1 - 0.095 13.0 0.1 16 5.9 0.0 2.8 3 0 0 3 3 2 0 TrfB plasmid transcriptional repressor rve_3 PF13683.6 KIR61360.1 - 0.1 12.4 0.1 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_ISL3 PF13542.6 KIR61360.1 - 0.22 11.0 3.6 6.4 6.3 0.2 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 KIR61360.1 - 0.35 11.2 6.1 13 6.2 0.2 3.7 3 1 0 3 3 3 0 Helix-turn-helix domain Beta_helix PF13229.6 KIR61361.1 - 2.8e-12 46.8 43.6 1.2e-07 31.7 19.4 2.3 1 1 2 3 3 3 3 Right handed beta helix region DUF4957 PF16318.5 KIR61361.1 - 0.012 15.6 1.7 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4957) Peptidase_M14 PF00246.24 KIR61362.1 - 2.4e-17 63.7 0.0 6.8e-17 62.2 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KIR61362.1 - 0.0034 16.5 0.1 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family AAA_19 PF13245.6 KIR61363.1 - 1.6e-13 51.2 0.0 1.5e-12 48.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIR61363.1 - 2e-10 40.7 0.0 0.00053 19.6 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIR61363.1 - 6.8e-08 32.2 0.0 2.1e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KIR61363.1 - 2.1e-06 27.6 2.2 0.049 13.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 KIR61363.1 - 5.4e-05 22.7 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 KIR61363.1 - 0.00048 19.5 0.1 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KIR61363.1 - 0.00095 19.0 0.0 0.019 14.7 0.0 2.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KIR61363.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61363.1 - 0.44 10.9 10.3 0.3 11.5 0.1 3.4 2 1 0 3 3 3 0 AAA ATPase domain FliG_M PF14841.6 KIR61366.1 - 0.14 12.4 0.3 0.81 10.0 0.3 2.4 1 0 0 1 1 1 0 FliG middle domain DUF2610 PF11020.8 KIR61367.1 - 1.4e-25 88.9 0.0 1.6e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2610) DUF2795 PF11387.8 KIR61367.1 - 0.16 12.2 0.5 0.73 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) CHAT PF12770.7 KIR61368.1 - 3.5e-28 98.9 0.0 7.2e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 CHAT domain DUF1771 PF08590.10 KIR61368.1 - 0.065 13.6 1.0 0.45 10.9 1.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) MLTR_LBD PF17765.1 KIR61369.1 - 1.3e-44 152.3 6.9 1.3e-44 152.3 6.9 1.4 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KIR61369.1 - 2e-15 56.9 14.6 2.4e-15 56.6 11.6 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61369.1 - 2.5e-07 30.6 0.1 6.8e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 KIR61369.1 - 0.0095 15.8 0.2 0.028 14.3 0.2 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Aldo_ket_red PF00248.21 KIR61370.1 - 6.4e-65 219.2 0.0 7.2e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_3 PF05977.13 KIR61372.1 - 1.8e-15 56.4 45.1 2.1e-15 56.1 45.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KIR61372.1 - 9.7e-15 54.3 60.2 6.7e-10 38.4 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIR61373.1 - 1.5e-17 63.6 36.3 1.5e-17 63.6 36.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR61373.1 - 4.2e-05 22.6 0.1 0.0001 21.3 0.1 1.8 1 1 0 1 1 1 1 MFS_1 like family AMP-binding PF00501.28 KIR61374.1 - 3.6e-88 296.0 0.1 5.4e-88 295.4 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR61374.1 - 6.4e-85 285.5 0.0 8.3e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KIR61374.1 - 4.3e-18 66.1 0.7 2.8e-17 63.4 0.2 2.7 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR61374.1 - 2.2e-12 47.1 0.0 7.1e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding PF00550.25 KIR61375.1 - 1.5e-13 50.9 0.3 1.8e-13 50.6 0.3 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KIR61376.1 - 1.2e-15 58.8 1.7 2.5e-15 57.7 0.5 2.2 2 2 1 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR61376.1 - 5e-09 36.2 0.1 9.8e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR61376.1 - 1e-08 35.0 0.0 2.8e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain APH PF01636.23 KIR61377.1 - 3.5e-19 69.7 3.9 4.4e-19 69.4 3.9 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family CBM_2 PF00553.19 KIR61378.1 - 2.2e-31 108.2 13.4 4.1e-31 107.3 13.4 1.5 1 0 0 1 1 1 1 Cellulose binding domain Reprolysin_4 PF13583.6 KIR61378.1 - 0.064 12.9 0.2 0.064 12.9 0.2 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KIR61378.1 - 0.12 12.9 0.4 0.48 10.9 0.2 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M6 PF05547.11 KIR61378.1 - 0.39 9.0 3.1 0.38 9.0 0.5 1.9 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 SBP_bac_8 PF13416.6 KIR61379.1 - 1.4e-33 116.9 6.9 1.9e-33 116.5 6.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR61379.1 - 5e-28 99.0 11.6 9.5e-28 98.1 11.6 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR61379.1 - 0.00036 20.0 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR61380.1 - 2.4e-20 73.1 12.2 2.4e-20 73.1 12.2 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Glyco_hydro_43 PF04616.14 KIR61381.1 - 3.5e-26 92.2 2.9 5.7e-26 91.5 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 F5_F8_type_C PF00754.25 KIR61381.1 - 1.4e-10 41.3 26.0 5.5e-07 29.7 7.8 3.9 3 1 0 4 4 4 2 F5/8 type C domain Big_4 PF07532.11 KIR61381.1 - 2.5e-07 30.3 1.2 2.5e-07 30.3 1.2 2.8 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 4) PsbQ PF05757.11 KIR61381.1 - 0.26 11.0 0.7 0.59 9.8 0.7 1.5 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Glyco_hydro_127 PF07944.12 KIR61383.1 - 8.4e-98 328.1 0.0 2.2e-87 293.8 0.0 2.4 2 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Laminin_G_3 PF13385.6 KIR61383.1 - 9.7e-33 113.5 3.1 9.7e-33 113.5 3.1 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Peripla_BP_3 PF13377.6 KIR61384.1 - 2.6e-27 96.2 0.2 3.8e-27 95.6 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR61384.1 - 4.5e-19 68.9 0.0 5.8e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR61384.1 - 1.8e-16 60.5 0.0 5.3e-16 59.0 0.0 1.7 1 1 1 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 KIR61384.1 - 1.9e-15 56.4 0.3 4.2e-15 55.2 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_6 PF13458.6 KIR61384.1 - 0.0046 16.7 0.2 0.013 15.1 0.2 1.7 1 1 1 2 2 2 1 Periplasmic binding protein HTH_31 PF13560.6 KIR61384.1 - 0.008 16.5 0.4 0.023 15.0 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61384.1 - 0.036 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_17 PF12728.7 KIR61384.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain DUF5635 PF18685.1 KIR61384.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Peripla_BP_3 PF13377.6 KIR61385.1 - 4.2e-39 134.5 0.7 4.2e-39 134.5 0.7 1.9 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR61385.1 - 5.8e-23 81.7 0.0 9.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR61385.1 - 2.9e-18 65.4 0.5 6.3e-18 64.3 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR61385.1 - 3.1e-16 59.7 0.0 4.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR61385.1 - 0.0039 17.5 0.9 0.018 15.4 0.9 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KIR61385.1 - 0.016 15.3 3.3 2.6 8.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_3 PF01381.22 KIR61385.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 KIR61385.1 - 0.03 13.7 0.0 0.13 11.7 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 KIR61385.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR61385.1 - 0.22 11.4 3.5 0.95 9.3 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Glyco_hydro_43 PF04616.14 KIR61386.1 - 1.4e-52 178.8 3.0 1.8e-52 178.5 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RicinB_lectin_2 PF14200.6 KIR61386.1 - 1.9e-23 83.0 6.8 2e-11 44.5 2.2 3.1 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR61386.1 - 6.5e-16 58.7 2.1 6.5e-15 55.5 2.3 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KIR61386.1 - 0.15 11.7 2.2 4.8 6.8 0.2 2.2 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain SWM_repeat PF13753.6 KIR61386.1 - 2.4 8.4 4.7 1.4 9.1 0.2 2.8 2 1 1 3 3 3 0 Putative flagellar system-associated repeat F5_F8_type_C PF00754.25 KIR61387.1 - 5.9e-13 49.0 1.2 5.9e-13 49.0 1.2 2.4 2 0 0 2 2 2 1 F5/8 type C domain CBM_6 PF03422.15 KIR61387.1 - 5.6e-10 39.6 4.8 5.6e-10 39.6 4.8 2.7 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) CBM_35 PF16990.5 KIR61387.1 - 4.5e-07 30.2 4.7 1.6e-06 28.4 4.7 2.0 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 KIR61387.1 - 0.00014 22.0 1.6 0.00014 22.0 1.6 2.2 2 0 0 2 2 2 1 DUF5010 C-terminal domain CBM_2 PF00553.19 KIR61388.1 - 1.7e-32 111.7 17.4 2e-32 111.5 11.2 2.4 2 0 0 2 2 2 2 Cellulose binding domain TPR_8 PF13181.6 KIR61389.1 - 0.0036 17.4 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIR61389.1 - 0.0049 16.6 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIR61389.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIR61389.1 - 0.012 16.4 0.4 0.028 15.2 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIR61389.1 - 0.021 14.8 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIR61389.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Inhibitor_I36 PF03995.13 KIR61390.1 - 6.7e-11 42.0 0.1 8.5e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor family I36 DEC-1_N PF04625.13 KIR61390.1 - 0.067 12.2 0.6 0.073 12.1 0.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF3029 PF11230.8 KIR61391.1 - 0.097 11.0 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) PQQ_2 PF13360.6 KIR61392.1 - 2.5e-18 66.5 16.6 2e-12 47.2 3.0 2.2 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 KIR61392.1 - 8.8e-13 47.5 6.7 0.026 14.4 0.0 6.9 7 1 0 7 7 7 3 PQQ enzyme repeat DUF799 PF05643.11 KIR61392.1 - 0.044 13.4 2.7 0.16 11.5 0.0 3.1 4 1 1 5 5 5 0 Putative bacterial lipoprotein (DUF799) PQQ_3 PF13570.6 KIR61392.1 - 0.44 11.1 0.1 0.44 11.1 0.1 6.7 7 1 0 7 7 7 0 PQQ-like domain Inhibitor_I36 PF03995.13 KIR61393.1 - 0.0025 17.7 3.2 0.0048 16.8 1.3 2.2 1 1 1 2 2 2 1 Peptidase inhibitor family I36 DUF3551 PF12071.8 KIR61394.1 - 8.5 6.5 7.5 1.3e+02 2.7 7.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3551) Peripla_BP_3 PF13377.6 KIR61395.1 - 2e-35 122.6 0.1 4.4e-35 121.5 0.1 1.6 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR61395.1 - 2.3e-19 69.9 0.0 2.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR61395.1 - 3.4e-15 55.6 0.5 1e-14 54.1 0.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 KIR61395.1 - 6.1e-10 39.3 2.3 2e-07 31.2 0.8 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain Peripla_BP_4 PF13407.6 KIR61395.1 - 1e-05 25.2 0.0 3.2e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 KIR61395.1 - 0.0011 18.9 0.1 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_IclR PF09339.10 KIR61395.1 - 0.01 15.6 0.2 0.046 13.5 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR61395.1 - 0.036 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 KIR61395.1 - 0.039 14.4 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 KIR61395.1 - 0.04 13.7 0.8 0.15 11.9 0.1 2.4 2 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KIR61395.1 - 0.067 12.6 0.1 0.24 10.8 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 KIR61395.1 - 0.18 11.6 0.2 0.69 9.7 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61395.1 - 0.4 10.5 1.9 1.6 8.6 0.2 2.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain SBP_bac_1 PF01547.25 KIR61396.1 - 8e-23 81.9 8.8 8e-23 81.9 8.8 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61396.1 - 3.4e-22 79.6 2.9 3.4e-22 79.6 2.9 1.7 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein F5_F8_type_C PF00754.25 KIR61397.1 - 1.6e-31 109.1 6.2 4.3e-22 78.6 3.3 2.8 2 0 0 2 2 2 2 F5/8 type C domain CARDB PF07705.11 KIR61397.1 - 7.8e-25 87.1 16.4 2.6e-23 82.2 2.9 4.1 3 1 0 3 3 3 2 CARDB DUF5000 PF16391.5 KIR61397.1 - 0.0019 18.3 0.1 1.1 9.4 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function fn3 PF00041.21 KIR61397.1 - 0.0072 16.7 4.9 4.3 7.8 0.0 5.4 6 0 0 6 6 6 1 Fibronectin type III domain Beta_helix PF13229.6 KIR61397.1 - 0.012 15.5 20.0 0.031 14.1 12.7 3.5 2 1 1 3 3 3 0 Right handed beta helix region ANAPC10 PF03256.16 KIR61397.1 - 0.031 13.9 0.0 6.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 10 (APC10) Sad1_UNC PF07738.13 KIR61397.1 - 0.087 12.8 0.0 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 Sad1 / UNC-like C-terminal HATPase_c PF02518.26 KIR61398.1 - 2.8e-20 72.9 0.0 4.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR61398.1 - 1.6e-17 63.3 1.0 2.5e-17 62.7 0.2 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KIR61398.1 - 0.0089 15.9 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR61398.1 - 0.019 14.9 0.2 0.058 13.4 0.2 1.8 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Lactamase_B_5 PF14597.6 KIR61398.1 - 0.029 13.9 2.3 0.26 10.8 0.1 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily HATPase_c_5 PF14501.6 KIR61398.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Methyltransf_11 PF08241.12 KIR61399.1 - 2.4e-07 31.3 0.3 7.8e-06 26.5 0.3 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61399.1 - 5.2e-07 30.3 0.1 1.1e-06 29.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR61399.1 - 8e-06 25.7 0.0 1.4e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61399.1 - 1.9e-05 25.4 0.2 0.00037 21.2 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR61399.1 - 0.00052 19.9 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR61399.1 - 0.043 13.4 0.1 0.076 12.6 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain MetW PF07021.12 KIR61399.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KIR61399.1 - 0.35 10.2 0.2 0.48 9.8 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glycos_transf_2 PF00535.26 KIR61400.1 - 4.6e-16 59.1 0.0 6.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 KIR61400.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Epimerase PF01370.21 KIR61401.1 - 3.5e-45 154.4 3.2 2.5e-44 151.6 3.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR61401.1 - 1e-34 120.5 0.0 1.8e-17 63.7 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR61401.1 - 1.2e-14 54.0 0.0 3.9e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIR61401.1 - 8.3e-11 42.1 1.6 8.3e-11 42.1 1.6 1.8 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIR61401.1 - 1.5e-08 34.1 1.1 0.00095 18.3 0.2 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIR61401.1 - 3.1e-07 29.8 0.0 0.00031 20.0 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIR61401.1 - 7e-07 28.7 0.0 0.00046 19.4 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KIR61401.1 - 6.5e-06 25.7 0.6 0.01 15.3 0.3 2.4 2 1 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.13 KIR61401.1 - 2.9e-05 23.7 0.1 7e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KIR61401.1 - 0.00026 20.6 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KIR61401.1 - 0.017 15.4 0.2 0.037 14.3 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KIR61401.1 - 0.028 15.0 1.9 0.029 14.9 0.5 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_4 PF13439.6 KIR61401.1 - 0.13 12.2 4.8 0.45 10.5 1.9 2.4 2 0 0 2 2 2 0 Glycosyltransferase Family 4 KR PF08659.10 KIR61401.1 - 0.25 11.2 3.6 1.6 8.6 3.2 2.5 2 1 0 2 2 2 0 KR domain HTH_5 PF01022.20 KIR61403.1 - 7.3e-16 57.8 0.2 1.1e-15 57.2 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR61403.1 - 9e-16 57.7 1.2 1.2e-15 57.3 0.5 1.5 2 0 0 2 2 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR61403.1 - 2.2e-09 37.1 0.3 4.4e-09 36.1 0.3 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR61403.1 - 1.8e-06 27.4 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR61403.1 - 5.7e-06 26.2 0.0 9.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KIR61403.1 - 7.7e-06 25.6 2.6 1.2e-05 25.0 0.8 2.0 1 1 1 2 2 2 1 IclR helix-turn-helix domain AbiEi_4 PF13338.6 KIR61403.1 - 0.00024 21.2 0.2 0.00069 19.7 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 KIR61403.1 - 0.00042 20.1 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 KIR61403.1 - 0.0018 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) PaaX PF07848.12 KIR61403.1 - 0.0038 17.4 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 PaaX-like protein HTH_Crp_2 PF13545.6 KIR61403.1 - 0.0045 16.9 0.2 0.0089 16.0 0.2 1.5 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KIR61403.1 - 0.0047 17.1 0.0 0.0075 16.5 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 KIR61403.1 - 0.0091 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.12 KIR61403.1 - 0.0095 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_34 PF13601.6 KIR61403.1 - 0.011 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 KIR61403.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain GntR PF00392.21 KIR61403.1 - 0.023 14.3 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 KIR61403.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61403.1 - 0.046 13.6 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain RP-C PF03428.13 KIR61403.1 - 0.046 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain 2C_adapt PF08793.10 KIR61403.1 - 0.054 13.7 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 2-cysteine adaptor domain Penicillinase_R PF03965.16 KIR61403.1 - 0.068 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor HTH_10 PF04967.12 KIR61403.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_1 PF00126.27 KIR61403.1 - 0.07 13.1 0.1 0.21 11.6 0.1 1.8 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family RepL PF05732.11 KIR61403.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Bac_rhamnosid6H PF17389.2 KIR61404.1 - 3.8e-89 299.3 0.0 5e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KIR61404.1 - 1.5e-39 135.6 0.0 2.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KIR61404.1 - 1.2e-16 60.5 0.0 2.4e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KIR61404.1 - 3.5e-08 33.1 0.0 9.2e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain ABC_tran PF00005.27 KIR61405.1 - 3.2e-26 92.5 0.0 4.1e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR61405.1 - 4e-15 56.1 0.1 7.5e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR61405.1 - 5.2e-07 29.8 0.0 3.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR61405.1 - 0.014 15.8 1.4 0.023 15.1 1.4 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIR61405.1 - 0.025 14.8 0.5 0.2 12.0 0.5 2.1 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIR61405.1 - 0.17 11.3 0.0 0.48 9.8 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR61405.1 - 0.19 11.8 0.0 0.5 10.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 KIR61405.1 - 0.25 11.4 0.0 0.38 10.8 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 KIR61406.1 - 1.9e-27 96.4 0.0 2.7e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR61406.1 - 1.5e-10 41.4 0.0 3.7e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 KIR61406.1 - 1.8e-05 25.1 0.3 7.2e-05 23.1 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIR61406.1 - 4.2e-05 23.5 0.2 0.0038 17.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR61406.1 - 0.0032 17.9 1.5 0.0067 16.8 1.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KIR61406.1 - 0.059 12.9 0.2 0.59 9.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIR61406.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 KIR61406.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KIR61406.1 - 0.27 11.1 0.3 0.44 10.4 0.3 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KIR61406.1 - 0.32 11.0 0.8 0.61 10.1 0.4 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SBP_bac_5 PF00496.22 KIR61407.1 - 9.6e-75 251.9 2.2 1.6e-74 251.2 2.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_3 PF00497.20 KIR61407.1 - 0.0017 17.8 0.3 0.0045 16.4 0.3 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 adh_short_C2 PF13561.6 KIR61408.1 - 3.6e-63 213.2 7.8 4.1e-63 213.1 7.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61408.1 - 1.4e-42 145.4 6.8 1.7e-42 145.1 6.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61408.1 - 3.4e-10 40.1 6.5 4.8e-10 39.6 6.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR61408.1 - 0.0016 17.9 5.8 0.0032 17.0 5.8 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR61408.1 - 0.011 14.9 5.4 0.016 14.3 4.9 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIR61408.1 - 0.11 11.4 0.5 0.16 10.9 0.5 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DegT_DnrJ_EryC1 PF01041.17 KIR61408.1 - 0.31 10.3 5.1 0.49 9.6 5.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 3HCDH_N PF02737.18 KIR61408.1 - 0.36 10.7 4.1 0.69 9.8 3.5 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR61409.1 - 4.5e-39 133.6 0.0 5.8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIR61409.1 - 9e-18 64.2 0.1 9.3e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIR61409.1 - 0.00044 20.5 0.0 0.00084 19.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 KIR61409.1 - 0.056 13.8 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIR61409.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 KIR61410.1 - 4.1e-23 81.4 0.5 2.3e-22 79.0 0.5 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR61410.1 - 1.3e-14 54.3 1.1 6.2e-14 52.1 1.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIR61410.1 - 1.3e-08 34.6 0.6 2e-08 34.0 0.6 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KIR61410.1 - 7.8e-05 22.1 0.5 0.0001 21.7 0.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIR61410.1 - 0.01 15.4 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KIR61410.1 - 0.01 16.9 0.1 0.019 16.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 KIR61410.1 - 0.048 14.2 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR61410.1 - 0.066 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KIR61410.1 - 0.11 13.3 0.1 0.24 12.1 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KIR61410.1 - 0.11 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAA_hydrolase PF01557.18 KIR61412.1 - 3.1e-62 210.1 0.0 3.6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Acyl-CoA_dh_1 PF00441.24 KIR61413.1 - 1e-34 119.9 2.9 1.6e-34 119.3 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR61413.1 - 5.9e-20 71.3 0.0 1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIR61413.1 - 2e-15 57.4 0.3 8.5e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIR61413.1 - 2.5e-12 47.2 1.4 2.5e-12 47.2 1.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KIR61413.1 - 0.00015 21.6 0.0 0.00031 20.5 0.0 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.23 KIR61414.1 - 2.4e-43 148.8 3.6 3e-43 148.5 3.6 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KIR61414.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KIR61414.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SprB PF13573.6 KIR61415.1 - 0.0021 17.8 2.0 0.0046 16.7 2.0 1.5 1 0 0 1 1 1 1 SprB repeat Ribonuc_red_lgC PF02867.15 KIR61416.1 - 1.3e-174 581.6 0.0 1.6e-174 581.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KIR61416.1 - 2.3e-16 59.6 0.0 5.3e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KIR61416.1 - 6.8e-14 52.2 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain Ribonuc_red_sm PF00268.21 KIR61417.1 - 4.5e-79 265.8 0.0 5.2e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF2204 PF09970.9 KIR61417.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Peripla_BP_3 PF13377.6 KIR61418.1 - 6.2e-41 140.5 5.7 1.2e-39 136.3 3.1 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR61418.1 - 3.4e-34 118.6 0.1 4.7e-34 118.1 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR61418.1 - 3.1e-23 82.7 0.0 4.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 KIR61418.1 - 3.4e-16 58.7 0.3 3.4e-16 58.7 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.6 KIR61418.1 - 0.00054 19.3 0.2 0.0041 16.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KIR61418.1 - 0.061 13.1 0.1 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain TetR_N PF00440.23 KIR61418.1 - 0.18 11.7 0.6 0.71 9.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family MerR PF00376.23 KIR61418.1 - 0.51 10.1 2.2 1.6 8.5 0.1 2.7 3 0 0 3 3 3 0 MerR family regulatory protein Aldo_ket_red PF00248.21 KIR61420.1 - 8.6e-59 199.1 0.0 9.7e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family KSHV_K8 PF07188.11 KIR61420.1 - 0.19 11.1 0.6 0.35 10.2 0.3 1.7 2 0 0 2 2 2 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Bac_rhamnosid6H PF17389.2 KIR61421.1 - 5.6e-129 430.2 0.0 7.3e-129 429.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KIR61421.1 - 3.6e-67 225.5 0.0 5.5e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KIR61421.1 - 7.2e-31 106.2 0.0 1.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KIR61421.1 - 1.2e-19 69.9 0.0 2e-18 66.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Cupin_2 PF07883.11 KIR61422.1 - 3.3e-12 45.9 1.3 5.6e-12 45.2 0.1 1.9 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.19 KIR61422.1 - 1.3e-06 28.3 0.1 1.8e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KIR61422.1 - 0.00041 20.3 0.0 0.00055 19.9 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 KIR61422.1 - 0.0018 17.9 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KIR61422.1 - 0.0024 18.1 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding_2 PF14525.6 KIR61422.1 - 0.022 14.5 0.2 0.043 13.5 0.2 1.5 1 0 0 1 1 1 0 AraC-binding-like domain Inositol_P PF00459.25 KIR61422.1 - 0.089 12.3 0.1 0.093 12.2 0.1 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family Cupin_2 PF07883.11 KIR61423.1 - 2.2e-17 62.5 0.3 3.8e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KIR61423.1 - 6.8e-08 32.1 0.0 7.7e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 KIR61423.1 - 1.3e-07 31.6 0.2 1.6e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIR61423.1 - 2.9e-06 27.0 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 KIR61423.1 - 0.00017 21.5 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 KIR61423.1 - 0.00033 20.8 0.0 0.00048 20.3 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_4 PF08007.12 KIR61423.1 - 0.00078 19.0 0.0 0.00096 18.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein ARD PF03079.14 KIR61423.1 - 0.031 14.5 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family PEP_hydrolase PF09370.10 KIR61424.1 - 2.4e-132 440.1 0.1 2.7e-132 439.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like 2-Hacid_dh_C PF02826.19 KIR61425.1 - 3.8e-43 146.9 0.0 5e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIR61425.1 - 2.9e-05 24.6 0.7 4.9e-05 23.8 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIR61425.1 - 7.2e-05 22.5 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KIR61425.1 - 0.00013 21.3 0.4 0.00019 20.8 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KIR61425.1 - 0.0021 18.3 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KIR61425.1 - 0.0049 17.4 0.1 0.012 16.1 0.1 1.7 2 0 0 2 2 1 1 XdhC Rossmann domain Oxidored_nitro PF00148.19 KIR61425.1 - 0.0075 15.0 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase 3HCDH_N PF02737.18 KIR61425.1 - 0.018 14.9 0.7 0.033 14.1 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIR61425.1 - 0.031 13.9 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 KIR61425.1 - 0.045 13.8 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KIR61425.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KIR61425.1 - 0.1 13.2 1.6 0.84 10.3 1.6 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KIR61425.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 KIR61425.1 - 0.22 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 ThiF family BPD_transp_1 PF00528.22 KIR61426.1 - 4.3e-15 55.9 21.1 4.3e-15 55.9 21.1 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR61427.1 - 2.1e-15 57.0 17.0 2.1e-15 57.0 17.0 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Amidohydro_2 PF04909.14 KIR61428.1 - 1.3e-15 58.0 13.5 1.6e-15 57.7 13.5 1.1 1 0 0 1 1 1 1 Amidohydrolase Malate_synthase PF01274.22 KIR61429.1 - 2.4e-184 613.5 0.0 2.9e-184 613.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF3248 PF11609.8 KIR61429.1 - 0.017 15.0 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) DUF5073 PF16817.5 KIR61429.1 - 0.099 12.7 1.2 0.29 11.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5073) PGDH_C PF16896.5 KIR61430.1 - 7.7e-58 194.9 0.3 1.4e-57 194.0 0.1 1.5 2 0 0 2 2 2 1 Phosphogluconate dehydrogenase (decarboxylating) C-term NAD_binding_2 PF03446.15 KIR61430.1 - 5e-06 26.8 0.1 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIR61430.1 - 1.7e-05 24.4 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 KIR61430.1 - 3.3e-05 23.8 1.5 3.3e-05 23.8 1.5 2.1 2 0 0 2 2 2 1 Rossmann-like domain F420_oxidored PF03807.17 KIR61430.1 - 3.7e-05 24.2 0.0 7.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KIR61430.1 - 9.4e-05 22.4 0.5 0.0056 16.7 0.5 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KIR61430.1 - 0.00074 18.9 0.1 0.0019 17.6 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KIR61430.1 - 0.00078 19.1 0.3 0.004 16.8 0.3 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIR61430.1 - 0.018 14.9 0.2 0.054 13.4 0.2 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KIR61430.1 - 0.082 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase DapB_N PF01113.20 KIR61430.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Dak1 PF02733.17 KIR61431.1 - 5.3e-102 340.9 0.2 7.8e-102 340.3 0.2 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KIR61431.1 - 4.4e-42 143.9 15.4 7.8e-42 143.1 15.4 1.4 1 0 0 1 1 1 1 DAK2 domain LacAB_rpiB PF02502.18 KIR61432.1 - 5.4e-41 139.8 0.1 6.1e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KIR61432.1 - 0.0023 18.0 0.2 0.0032 17.5 0.2 1.3 1 0 0 1 1 1 1 Glycine-rich SFCGS AP_endonuc_2 PF01261.24 KIR61433.1 - 3.7e-18 65.7 0.0 5.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_25 PF13649.6 KIR61435.1 - 1.4e-06 28.9 0.1 2.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIR61435.1 - 0.0016 17.6 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KIR61435.1 - 0.0053 17.5 0.0 0.008 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61435.1 - 0.009 16.6 0.1 0.015 16.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIR61435.1 - 0.09 12.9 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.10 KIR61435.1 - 0.18 11.4 0.1 5.9 6.5 0.0 2.0 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Abhydrolase_3 PF07859.13 KIR61436.1 - 1.9e-49 168.4 0.4 2.8e-49 167.9 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIR61436.1 - 4.4e-09 35.8 0.1 8.3e-09 34.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIR61436.1 - 0.044 13.2 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family ABM PF03992.16 KIR61437.1 - 7.4e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ferritin PF00210.24 KIR61438.1 - 1.2e-11 44.7 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain AAA_16 PF13191.6 KIR61439.1 - 1.8e-16 61.0 0.4 1.8e-16 61.0 0.4 3.2 3 1 0 3 3 3 1 AAA ATPase domain GerE PF00196.19 KIR61439.1 - 3.5e-16 58.5 0.0 6.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_19 PF14559.6 KIR61439.1 - 8.5e-07 29.4 7.5 0.0002 21.8 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Sigma70_r4_2 PF08281.12 KIR61439.1 - 2.1e-06 27.3 1.3 0.013 15.1 0.0 4.1 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR61439.1 - 0.0011 18.7 0.0 0.0052 16.6 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain AAA_22 PF13401.6 KIR61439.1 - 0.0025 18.1 0.0 0.014 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain TPR_4 PF07721.14 KIR61439.1 - 0.0062 17.1 44.9 0.0066 17.0 0.7 8.5 7 0 0 7 7 6 3 Tetratricopeptide repeat AAA_29 PF13555.6 KIR61439.1 - 0.032 14.0 0.1 0.092 12.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HTH_28 PF13518.6 KIR61439.1 - 0.04 14.1 0.0 0.18 12.0 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR61439.1 - 0.047 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KIR61439.1 - 0.077 12.8 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 KIR61439.1 - 0.32 11.6 7.0 0.7 10.6 0.1 3.6 3 0 0 3 3 2 0 Homeodomain-like domain AraC_N PF06719.13 KIR61440.1 - 4.8e-47 159.3 0.0 6.9e-47 158.8 0.0 1.2 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 KIR61440.1 - 1.5e-18 66.8 0.3 3.6e-18 65.6 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR61440.1 - 4.3e-18 64.9 0.1 4.5e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 KIR61440.1 - 0.01 15.8 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain TetR_N PF00440.23 KIR61440.1 - 0.01 15.6 0.4 0.14 11.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family Ribosomal_S14 PF00253.21 KIR61440.1 - 0.15 11.8 0.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e adh_short PF00106.25 KIR61441.1 - 5.7e-43 146.6 0.3 7.8e-43 146.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR61441.1 - 3.3e-31 108.7 0.1 4.4e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIR61441.1 - 7.4e-08 32.1 0.1 1.9e-07 30.8 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR61441.1 - 2.7e-06 27.4 0.2 4.3e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KIR61441.1 - 0.00042 20.3 0.0 0.00084 19.3 0.0 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KIR61441.1 - 0.00095 18.3 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 KIR61441.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RhaA PF06134.11 KIR61442.1 - 4.8e-07 29.2 0.0 6.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 L-rhamnose isomerase (RhaA) adh_short_C2 PF13561.6 KIR61443.1 - 2.7e-47 161.3 8.2 8e-47 159.7 8.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61443.1 - 5e-43 146.9 4.0 9.2e-43 146.0 4.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Aldolase_II PF00596.21 KIR61443.1 - 1.7e-24 86.8 0.1 2.4e-23 83.1 0.0 2.6 3 0 0 3 3 3 1 Class II Aldolase and Adducin N-terminal domain KR PF08659.10 KIR61443.1 - 2.2e-08 34.2 4.4 4.6e-08 33.2 4.4 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR61443.1 - 0.00021 20.8 0.4 0.00058 19.4 0.5 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIR61443.1 - 0.0014 18.7 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 KIR61443.1 - 0.023 13.8 1.3 0.037 13.1 1.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIR61443.1 - 0.071 13.0 4.6 0.14 12.0 4.6 1.5 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 KIR61443.1 - 0.14 12.5 1.2 0.29 11.4 0.9 1.8 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KIR61443.1 - 0.42 10.5 2.1 0.77 9.6 2.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4684 PF15736.5 KIR61443.1 - 9.8 4.7 8.2 21 3.6 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) FGGY_C PF02782.16 KIR61444.1 - 1.5e-33 116.2 0.0 2.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIR61444.1 - 4.8e-24 85.3 0.0 6.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CCG PF02754.16 KIR61445.1 - 6.1e-34 116.1 0.1 1.2e-15 57.5 0.1 2.2 2 0 0 2 2 2 2 Cysteine-rich domain LUD_dom PF02589.15 KIR61446.1 - 1.3e-43 148.9 0.2 2.9e-43 147.8 0.2 1.5 1 1 0 1 1 1 1 LUD domain DUF3390 PF11870.8 KIR61446.1 - 7.4e-13 48.7 1.1 1.5e-12 47.7 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4_8 PF13183.6 KIR61446.1 - 1.7e-08 34.8 3.8 2.6e-07 31.0 4.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KIR61446.1 - 3.3e-05 23.5 11.4 0.025 14.4 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIR61446.1 - 4.1e-05 24.0 2.1 0.00031 21.2 3.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR61446.1 - 4.4e-05 23.5 6.6 0.0005 20.1 7.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR61446.1 - 8.7e-05 23.0 5.4 0.00029 21.4 5.4 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIR61446.1 - 0.00023 21.0 12.7 0.0059 16.6 3.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIR61446.1 - 0.00067 20.0 7.3 0.22 12.1 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KIR61446.1 - 0.0034 17.4 11.7 0.27 11.4 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KIR61446.1 - 0.0048 17.7 12.7 0.26 12.3 4.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KIR61446.1 - 0.0051 17.0 7.6 0.22 11.7 2.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KIR61446.1 - 0.025 14.7 6.4 0.071 13.2 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR61446.1 - 0.03 15.3 9.7 0.29 12.1 9.7 2.2 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KIR61446.1 - 0.039 14.1 4.3 0.84 9.9 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 KIR61446.1 - 0.067 13.0 2.0 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_13 PF13370.6 KIR61446.1 - 2.3 8.8 8.2 38 4.9 8.2 2.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Glyoxalase_6 PF18029.1 KIR61447.1 - 2.7e-24 86.0 0.1 3.1e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KIR61447.1 - 0.0027 17.9 0.0 0.0033 17.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hyd_65N_2 PF14498.6 KIR61448.1 - 3.9e-70 236.4 0.7 6.3e-70 235.7 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain CBM_2 PF00553.19 KIR61448.1 - 5.4e-24 84.4 12.1 5.4e-24 84.4 12.1 2.5 2 0 0 2 2 2 1 Cellulose binding domain TAT_signal PF10518.9 KIR61448.1 - 3.9e-05 23.3 2.9 3.9e-05 23.3 2.9 3.0 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence COBRA PF04833.15 KIR61448.1 - 2 8.3 3.6 0.5 10.2 0.1 1.7 2 0 0 2 2 2 0 COBRA-like protein ICL PF00463.21 KIR61449.1 - 1e-99 334.4 0.2 1.6e-52 178.7 0.0 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 KIR61449.1 - 3.1e-17 62.8 0.4 6e-17 61.9 0.4 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Malate_synthase PF01274.22 KIR61450.1 - 9.8e-186 618.1 0.0 1.1e-185 617.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase LppA PF16708.5 KIR61450.1 - 0.0069 16.3 0.2 0.038 13.9 0.2 2.0 2 0 0 2 2 2 1 Lipoprotein confined to pathogenic Mycobacterium SLATT_3 PF18184.1 KIR61450.1 - 0.13 12.4 0.5 0.24 11.5 0.5 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 IclR PF01614.18 KIR61451.1 - 8.4e-38 129.1 0.1 1.4e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR61451.1 - 7.9e-17 60.8 1.8 7.9e-17 60.8 1.8 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR61451.1 - 8.2e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR61451.1 - 0.00046 20.0 0.5 0.00046 20.0 0.5 2.1 2 0 0 2 2 2 1 MarR family DUF977 PF06163.11 KIR61451.1 - 0.0039 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) HTH_AsnC-type PF13404.6 KIR61451.1 - 0.034 14.0 1.4 0.064 13.1 0.4 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KIR61451.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 KIR61451.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix TrmB PF01978.19 KIR61451.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB EAP30 PF04157.16 KIR61451.1 - 0.17 11.1 0.1 8.2 5.6 0.0 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family Thiolase_N PF00108.23 KIR61452.1 - 5.3e-69 232.5 0.0 6.8e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR61452.1 - 5.8e-39 132.5 0.2 5.8e-39 132.5 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR61452.1 - 0.025 14.2 0.8 0.025 14.2 0.8 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain CoA_trans PF01144.23 KIR61453.1 - 9.4e-38 129.8 0.0 1.1e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hydro PF02550.15 KIR61453.1 - 0.048 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.23 KIR61454.1 - 2.9e-22 79.2 0.0 3.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme A transferase CMD PF02627.20 KIR61455.1 - 3.4e-27 94.3 0.5 3.4e-27 94.3 0.5 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Abhydrolase_1 PF00561.20 KIR61456.1 - 2.1e-23 83.3 0.1 1e-21 77.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR61456.1 - 2.3e-16 61.1 25.4 3.4e-16 60.5 25.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR61456.1 - 7.6e-10 38.5 1.3 1.3e-08 34.5 0.7 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR61456.1 - 0.00011 22.3 0.4 0.0011 19.1 0.1 2.1 2 0 0 2 2 2 1 TAP-like protein Esterase PF00756.20 KIR61456.1 - 0.0013 18.5 0.3 0.0075 15.9 0.1 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KIR61456.1 - 0.0044 16.5 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 KIR61456.1 - 0.014 15.3 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 Serine hydrolase Esterase_phd PF10503.9 KIR61456.1 - 0.088 12.3 8.0 0.018 14.5 3.3 1.9 1 1 1 2 2 2 0 Esterase PHB depolymerase UPF0227 PF05728.12 KIR61456.1 - 0.17 11.8 0.0 8.9 6.2 0.0 2.5 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0227) Lyase_1 PF00206.20 KIR61457.1 - 2.3e-32 112.7 0.0 3.2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KIR61457.1 - 1.9e-14 53.9 2.6 2e-13 50.7 0.1 3.4 3 1 1 4 4 4 1 Adenylosuccinate lyase C-terminus Dioxygenase_C PF00775.21 KIR61458.1 - 7.2e-18 64.7 0.0 4.2e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.6 KIR61458.1 - 0.076 13.3 0.3 0.56 10.5 0.3 2.3 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Dioxygenase_C PF00775.21 KIR61459.1 - 1.3e-54 184.4 0.0 1.6e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 KIR61459.1 - 7.1e-16 57.5 6.7 1.7e-15 56.3 6.7 1.7 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 KIR61459.1 - 2.7e-06 27.5 0.0 6.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 KIR61459.1 - 0.08 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) G_glu_transpept PF01019.21 KIR61460.1 - 4.7e-88 296.2 0.7 3.2e-87 293.4 0.7 1.8 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase PTE PF02126.18 KIR61461.1 - 3.1e-59 200.9 0.0 4.2e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotriesterase family MFS_1 PF07690.16 KIR61462.1 - 1.3e-38 132.9 74.5 1.4e-26 93.3 39.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR61462.1 - 3.7e-10 39.2 21.7 2e-06 27.0 9.3 2.2 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KIR61462.1 - 7.1e-06 25.2 12.0 7.1e-06 25.2 12.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4191 PF13829.6 KIR61462.1 - 0.052 12.9 0.3 0.052 12.9 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) MFS_3 PF05977.13 KIR61462.1 - 0.44 8.9 52.2 1.1 7.6 31.7 2.4 1 1 1 2 2 2 0 Transmembrane secretion effector Metal_resist PF13801.6 KIR61462.1 - 0.98 9.6 7.9 11 6.2 0.5 3.1 2 0 0 2 2 2 0 Heavy-metal resistance OATP PF03137.20 KIR61462.1 - 6.1 5.0 11.8 4.5 5.4 3.2 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family YjgF_endoribonc PF14588.6 KIR61463.1 - 3.3e-13 50.0 0.0 3.9e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease TauE PF01925.19 KIR61464.1 - 2.8e-35 122.0 42.6 3.2e-35 121.9 42.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE BacteriocIIc_cy PF12173.8 KIR61464.1 - 0.052 13.8 2.3 0.052 13.8 2.3 2.5 3 1 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like G_glu_transpept PF01019.21 KIR61465.1 - 1.7e-105 353.7 0.0 2e-105 353.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Amidohydro_3 PF07969.11 KIR61466.1 - 1.2e-51 176.7 6.9 4e-48 165.1 1.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIR61466.1 - 6.5e-13 48.7 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family BPD_transp_1 PF00528.22 KIR61467.1 - 5.1e-07 29.6 18.9 5.1e-07 29.6 18.9 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR61468.1 - 3.1e-13 49.9 14.7 3.1e-13 49.9 14.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KIR61469.1 - 3.9e-35 121.3 0.0 7.6e-35 120.4 0.0 1.5 2 0 0 2 2 1 1 ABC transporter TOBE_2 PF08402.10 KIR61469.1 - 3.6e-10 39.9 1.1 8.8e-10 38.6 0.5 2.1 2 0 0 2 2 1 1 TOBE domain AAA_21 PF13304.6 KIR61469.1 - 4e-08 33.4 0.3 0.0022 17.9 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR61469.1 - 3.6e-06 26.6 0.8 0.00018 21.0 0.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIR61469.1 - 0.0024 17.8 0.6 0.0058 16.5 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KIR61469.1 - 0.0031 17.6 0.1 0.015 15.4 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KIR61469.1 - 0.0089 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR61469.1 - 0.01 16.2 1.2 0.031 14.6 1.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KIR61469.1 - 0.02 14.4 0.4 0.92 9.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 KIR61469.1 - 0.038 14.4 0.0 7 7.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIR61469.1 - 0.071 13.4 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR61469.1 - 0.081 12.8 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIR61469.1 - 0.09 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KIR61469.1 - 0.091 13.0 0.1 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIR61469.1 - 0.095 13.2 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIR61469.1 - 0.16 11.5 3.8 1.7 8.2 2.8 2.8 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIR61469.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PTE PF02126.18 KIR61470.1 - 5.4e-23 81.9 0.0 6.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotriesterase family Aldedh PF00171.22 KIR61471.1 - 2.3e-172 573.7 0.1 2.7e-172 573.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.20 KIR61472.1 - 5.1e-144 480.2 0.0 6.1e-144 479.9 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KIR61472.1 - 1.1e-16 61.1 0.0 2.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain DUF2866 PF11065.8 KIR61472.1 - 0.063 13.3 0.8 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) PTE PF02126.18 KIR61473.1 - 1.2e-49 169.3 0.0 3.6e-48 164.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotriesterase family Cupin_3 PF05899.12 KIR61474.1 - 1.5e-19 69.4 0.9 2e-19 69.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KIR61474.1 - 5.3e-06 26.0 0.3 1e-05 25.1 0.3 1.5 1 1 0 1 1 1 1 Cupin domain EutQ PF06249.12 KIR61474.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ MBT PF02820.18 KIR61474.1 - 0.026 14.9 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 mbt repeat Ppnp PF06865.11 KIR61474.1 - 0.077 13.4 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase Fer2 PF00111.27 KIR61475.1 - 4e-11 42.7 2.9 6.3e-11 42.1 2.9 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 KIR61475.1 - 0.014 15.5 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KIR61475.1 - 0.15 12.7 0.0 4.7 7.9 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Rieske PF00355.26 KIR61476.1 - 1.1e-16 60.5 0.0 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Aromatic_hydrox PF11723.8 KIR61476.1 - 2.9e-06 27.0 0.8 0.00059 19.4 0.2 2.9 2 1 0 2 2 2 1 Homotrimeric ring hydroxylase Ring_hydroxyl_A PF00848.19 KIR61476.1 - 0.019 15.0 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) SBP_bac_8 PF13416.6 KIR61477.1 - 7.1e-26 91.7 5.8 3.5e-25 89.4 4.9 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR61477.1 - 3e-09 36.7 0.3 4.2e-09 36.2 0.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF1989 PF09347.10 KIR61478.1 - 4.8e-37 127.2 0.0 5.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF1989 PF09347.10 KIR61479.1 - 1.2e-60 204.0 0.0 1.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF5134 PF17197.4 KIR61480.1 - 3.7e-24 85.4 32.9 3.7e-24 85.4 32.9 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5134) HtaA PF04213.13 KIR61481.1 - 1.8e-41 142.3 2.0 1.8e-41 142.3 2.0 1.8 2 0 0 2 2 2 1 Htaa WxL PF13731.6 KIR61481.1 - 9.2e-05 22.6 0.1 0.00079 19.5 0.0 2.5 1 1 0 1 1 1 1 WxL domain surface cell wall-binding TIG PF01833.24 KIR61481.1 - 0.039 14.0 0.0 0.18 11.9 0.0 2.2 1 0 0 1 1 1 0 IPT/TIG domain Neocarzinostat PF00960.18 KIR61482.1 - 8.5e-05 22.5 2.3 8.5e-05 22.5 2.3 3.5 2 1 2 4 4 4 2 Neocarzinostatin family DUF4381 PF14316.6 KIR61482.1 - 0.064 13.5 1.2 0.12 12.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FecCD PF01032.18 KIR61483.1 - 2e-90 303.0 34.0 2.5e-90 302.7 34.0 1.1 1 0 0 1 1 1 1 FecCD transport family Oxidored_FMN PF00724.20 KIR61484.1 - 2.1e-66 224.6 0.0 2.9e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KIR61484.1 - 4.8e-09 35.9 3.1 2.5e-08 33.5 3.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR61484.1 - 6.5e-09 35.9 6.9 3.1e-06 27.3 1.6 3.8 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIR61484.1 - 2.7e-07 31.1 0.2 0.048 14.2 0.3 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR61484.1 - 6.4e-06 25.8 3.9 6.4e-06 25.8 3.9 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR61484.1 - 8.8e-05 21.4 0.6 0.00016 20.6 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Toprim_3 PF13362.6 KIR61484.1 - 0.0047 17.3 1.0 0.13 12.7 0.1 2.9 2 0 0 2 2 2 1 Toprim domain GIDA PF01134.22 KIR61484.1 - 0.01 15.0 0.8 0.01 15.0 0.8 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KIR61484.1 - 0.02 14.2 5.8 0.033 13.5 3.8 2.3 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIR61484.1 - 0.024 13.9 0.5 0.05 12.9 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DFP PF04127.15 KIR61484.1 - 0.085 12.7 1.8 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Pyr_redox_3 PF13738.6 KIR61484.1 - 0.18 11.0 0.8 1.1 8.4 0.2 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2345 PF10106.9 KIR61484.1 - 0.71 9.7 4.2 4.4 7.2 0.2 3.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2345) Methyltransf_25 PF13649.6 KIR61485.1 - 1.2e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61485.1 - 2.3e-18 66.6 0.0 3.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR61485.1 - 1.9e-10 40.7 0.0 2.9e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR61485.1 - 2.7e-09 37.1 0.0 3.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61485.1 - 5.3e-09 36.7 0.0 9.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR61485.1 - 9.4e-09 34.9 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIR61485.1 - 1.9e-08 34.1 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KIR61485.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KIR61485.1 - 0.003 17.1 0.0 0.0087 15.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase DUF2993 PF11209.8 KIR61485.1 - 0.0037 17.5 0.2 0.0075 16.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Methyltransf_8 PF05148.15 KIR61485.1 - 0.004 17.0 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KIR61485.1 - 0.0071 15.7 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KIR61485.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_2 PF12680.7 KIR61487.1 - 6.1e-07 30.0 0.1 7.9e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIR61487.1 - 6.9e-06 26.4 0.0 9.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 KIR61487.1 - 0.1 12.4 0.0 1.1 9.1 0.0 2.0 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase NMT1 PF09084.11 KIR61488.1 - 9e-32 110.8 0.9 1.1e-31 110.5 0.9 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KIR61488.1 - 3.8e-11 43.1 0.7 6e-11 42.4 0.7 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 KIR61488.1 - 1.1e-09 38.4 0.6 1e-08 35.2 0.6 2.1 1 1 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 KIR61488.1 - 6.1e-08 32.4 0.2 1.1e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 KIR61488.1 - 1.3e-05 24.8 0.6 0.049 13.0 0.2 2.2 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 KIR61488.1 - 0.002 17.8 1.7 0.002 17.8 1.7 1.9 2 1 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system LPAM_2 PF13627.6 KIR61488.1 - 0.72 9.8 4.2 1.9 8.4 4.2 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site BPD_transp_1 PF00528.22 KIR61489.1 - 1.9e-27 96.2 20.1 3.4e-27 95.4 20.1 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.21 KIR61489.1 - 0.023 15.2 4.9 0.023 15.2 4.9 2.5 2 0 0 2 2 2 0 FtsX-like permease family MtrF PF09472.10 KIR61489.1 - 1.6 8.2 6.6 6.3 6.3 1.0 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) adh_short_C2 PF13561.6 KIR61490.1 - 8.7e-64 215.3 6.0 1.1e-63 214.9 6.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61490.1 - 1.7e-44 151.7 3.7 5.3e-44 150.0 3.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61490.1 - 1.7e-06 28.1 1.0 0.00022 21.2 1.0 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR61490.1 - 0.0022 17.5 0.3 0.0022 17.5 0.3 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Peptidase_M20 PF01546.28 KIR61491.1 - 1.3e-21 77.2 0.0 2.4e-21 76.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIR61491.1 - 7.3e-09 35.5 0.0 1.3e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_1 PF00561.20 KIR61492.1 - 3e-17 63.1 0.0 4.6e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR61492.1 - 4.8e-13 50.2 20.1 6.1e-13 49.9 20.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR61492.1 - 1.3e-09 37.7 0.3 1.1e-06 28.1 0.0 2.8 2 2 1 3 3 3 2 Serine aminopeptidase, S33 Ndr PF03096.14 KIR61492.1 - 0.045 12.5 0.0 0.14 10.8 0.0 1.8 2 0 0 2 2 2 0 Ndr family EamA PF00892.20 KIR61493.1 - 4.2e-33 114.4 24.7 1.2e-17 64.4 11.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family IclR PF01614.18 KIR61494.1 - 5.9e-30 103.7 0.0 9.8e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR61494.1 - 2.7e-09 36.7 0.0 2.7e-09 36.7 0.0 2.6 3 1 0 3 3 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR61494.1 - 1.2e-05 25.1 1.4 0.00041 20.2 0.0 3.0 3 0 0 3 3 3 1 MarR family TrmB PF01978.19 KIR61494.1 - 0.0028 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 KIR61494.1 - 0.0037 17.6 0.0 0.081 13.3 0.0 2.7 3 0 0 3 3 3 1 Transcriptional regulator CoA_transf_3 PF02515.17 KIR61495.1 - 4.2e-117 391.4 0.5 4.7e-117 391.2 0.5 1.0 1 0 0 1 1 1 1 CoA-transferase family III Cyclase PF04199.13 KIR61496.1 - 1.7e-31 109.3 0.1 2.7e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase MmgE_PrpD PF03972.14 KIR61497.1 - 6e-119 397.5 9.5 7.9e-119 397.1 9.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Amidohydro_1 PF01979.20 KIR61498.1 - 1.4e-13 50.9 0.0 4.9e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIR61498.1 - 3e-09 36.9 1.0 1.4e-05 24.8 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family TetR_C_7 PF14246.6 KIR61498.1 - 0.0057 16.7 0.3 0.01 15.8 0.3 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain HpcH_HpaI PF03328.14 KIR61499.1 - 1e-34 119.6 0.2 1.5e-34 119.1 0.2 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KIR61499.1 - 4.6e-09 35.9 0.0 0.00019 20.7 0.0 2.6 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold SBP_bac_3 PF00497.20 KIR61499.1 - 0.089 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 RuvA_C PF07499.13 KIR61499.1 - 0.29 11.6 4.4 0.43 11.1 0.7 3.1 2 0 0 2 2 2 0 RuvA, C-terminal domain Abhydrolase_1 PF00561.20 KIR61500.1 - 2.3e-31 109.4 0.1 5.3e-31 108.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR61500.1 - 1.1e-22 81.7 4.5 1.3e-22 81.5 4.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR61500.1 - 1.1e-21 77.2 0.1 6.7e-21 74.6 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIR61500.1 - 0.0067 16.3 0.0 7 6.4 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF915 PF06028.11 KIR61500.1 - 0.032 13.5 0.0 0.18 11.1 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KIR61500.1 - 0.045 13.5 0.0 2.8 7.7 0.0 2.7 2 1 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIR61500.1 - 0.08 12.5 0.1 1.2 8.7 0.1 2.2 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.10 KIR61500.1 - 0.17 10.9 0.0 0.8 8.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Ferritin PF00210.24 KIR61501.1 - 1.1e-19 70.8 0.1 1.2e-19 70.7 0.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain TFIIA_gamma_N PF02268.16 KIR61501.1 - 0.12 12.4 0.2 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain ABC_tran PF00005.27 KIR61502.1 - 1.8e-27 96.5 0.0 2.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR61502.1 - 0.0001 22.7 0.6 0.00017 22.0 0.6 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIR61502.1 - 0.00017 21.5 0.1 0.51 10.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIR61502.1 - 0.0024 17.6 1.1 0.0055 16.5 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIR61502.1 - 0.016 15.6 0.2 0.081 13.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIR61502.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 KIR61502.1 - 0.036 14.3 2.0 0.052 13.8 0.7 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KIR61502.1 - 0.036 14.3 0.2 0.23 11.7 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KIR61502.1 - 0.038 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR61502.1 - 0.042 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIR61502.1 - 0.059 13.3 1.1 0.14 12.0 0.1 2.0 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 KIR61502.1 - 0.066 13.6 0.5 0.3 11.5 0.2 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIR61502.1 - 0.074 13.3 0.7 0.23 11.7 0.7 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIR61502.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NMT1_2 PF13379.6 KIR61503.1 - 5.4e-09 36.1 0.0 1.2e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 KIR61503.1 - 1.8e-08 34.3 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KIR61503.1 - 1.7e-07 31.4 0.0 4.6e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like VitK2_biosynth PF02621.14 KIR61503.1 - 0.00034 20.2 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Menaquinone biosynthesis SBP_bac_3 PF00497.20 KIR61503.1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 KIR61503.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family NMT1 PF09084.11 KIR61504.1 - 3.1e-10 40.4 0.0 0.00026 21.0 0.0 2.5 2 1 0 2 2 2 2 NMT1/THI5 like NMT1_2 PF13379.6 KIR61504.1 - 2.6e-05 24.1 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 2 NMT1-like family SBP_bac_3 PF00497.20 KIR61504.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Adeno_PIX PF03955.14 KIR61505.1 - 6.3 7.0 12.5 15 5.8 0.8 4.0 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Glyco_hydro_130 PF04041.13 KIR61506.1 - 2.5e-32 112.1 0.0 1.3e-31 109.8 0.0 1.9 1 1 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase BPD_transp_1 PF00528.22 KIR61507.1 - 2.3e-17 63.4 15.3 2.3e-17 63.4 15.3 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 KIR61509.1 - 2e-13 51.0 0.0 5.6e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61509.1 - 2.4e-07 30.9 0.0 1.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR61509.1 - 0.005 16.6 0.3 2 8.1 0.0 2.8 2 1 1 3 3 3 2 Bacterial extracellular solute-binding protein PknG_TPR PF16918.5 KIR61510.1 - 1.8e-61 207.8 14.0 2.7e-61 207.2 14.0 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat Pkinase PF00069.25 KIR61510.1 - 1.2e-27 96.9 0.0 1.6e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR61510.1 - 4.4e-13 49.1 0.0 6.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PknG_rubred PF16919.5 KIR61510.1 - 7e-13 48.9 0.5 7e-13 48.9 0.5 2.2 2 0 0 2 2 2 1 Protein kinase G rubredoxin domain WaaY PF06176.11 KIR61510.1 - 0.00048 19.8 0.0 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) TPR_19 PF14559.6 KIR61510.1 - 0.00072 20.0 11.6 0.0015 19.0 0.8 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat zf-NADH-PPase PF09297.11 KIR61510.1 - 0.4 10.4 5.3 0.19 11.5 0.5 2.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KIR61510.1 - 5.1 7.0 9.4 6.6 6.6 2.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Trypsin_2 PF13365.6 KIR61511.1 - 2.5e-13 51.2 0.9 6.5e-13 49.8 0.9 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KIR61511.1 - 0.0016 18.3 0.0 0.0049 16.7 0.0 1.8 1 1 0 1 1 1 1 Trypsin Thioesterase PF00975.20 KIR61512.1 - 1.6e-41 142.9 0.0 1.9e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KIR61512.1 - 9.9e-09 36.1 21.9 1.3e-08 35.7 21.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR61512.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIR61512.1 - 0.0021 17.9 0.1 0.0029 17.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KIR61512.1 - 0.0063 16.2 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 KIR61512.1 - 0.067 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 KIR61513.1 - 9.4e-23 82.0 20.8 1.5e-22 81.3 20.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR61513.1 - 7.6e-18 65.1 0.0 1.4e-15 57.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR61513.1 - 7.5e-14 51.6 0.0 1.2e-13 50.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIR61513.1 - 4.2e-05 23.8 0.0 6.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 KIR61513.1 - 0.032 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ser_hydrolase PF06821.13 KIR61513.1 - 0.081 12.8 0.1 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase Glyoxalase_3 PF13468.6 KIR61515.1 - 2.3e-38 132.0 0.2 4.7e-33 114.8 0.1 2.0 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIR61515.1 - 5.8e-12 45.8 0.0 3.2e-06 27.4 0.0 3.1 1 1 2 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KIR61515.1 - 0.048 13.8 0.0 1.4 9.1 0.0 2.9 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HTH_1 PF00126.27 KIR61516.1 - 1.2e-18 66.8 3.4 1.2e-18 66.8 3.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 KIR61516.1 - 2.2e-13 50.0 12.9 4.1e-13 49.2 12.9 1.5 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 KIR61516.1 - 0.00014 21.6 0.2 0.00047 19.9 0.2 2.0 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR61516.1 - 0.0026 17.6 2.1 0.0062 16.3 0.2 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 KIR61516.1 - 0.007 16.2 0.5 0.035 14.0 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 KIR61516.1 - 0.007 15.9 0.7 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TmoB PF06234.12 KIR61516.1 - 0.1 12.7 0.6 0.26 11.4 0.6 1.6 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) AMP-binding PF00501.28 KIR61517.1 - 1.8e-05 23.6 0.0 8.7e-05 21.3 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Chorismate_bind PF00425.18 KIR61518.1 - 5.5e-90 301.4 0.0 8e-90 300.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KIR61518.1 - 1.3e-11 44.8 0.0 7.2e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region GATase PF00117.28 KIR61519.1 - 8.1e-47 159.5 0.0 9e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIR61519.1 - 4.5e-08 33.1 0.0 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 AMP-binding PF00501.28 KIR61520.1 - 1.7e-14 53.2 0.0 2.9e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme MbtH PF03621.13 KIR61520.1 - 6.6e-11 41.5 0.0 1.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 MbtH-like protein Response_reg PF00072.24 KIR61521.1 - 1.6e-23 83.0 0.0 2.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR61521.1 - 8.7e-18 63.6 0.0 1.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 KIR61521.1 - 3.2e-06 26.5 0.7 0.00014 21.3 0.1 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIR61521.1 - 1.9e-05 24.3 0.1 4.1e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 KIR61521.1 - 0.0018 18.7 0.1 0.0032 17.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KIR61521.1 - 0.0018 17.8 0.0 0.0041 16.7 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 KIR61521.1 - 0.0025 17.9 0.1 0.0097 16.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KIR61521.1 - 0.0025 17.6 1.6 0.018 14.8 0.1 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 KIR61521.1 - 0.0065 16.5 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_5 PF01022.20 KIR61521.1 - 0.0093 15.8 0.0 0.05 13.5 0.0 2.0 1 1 1 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR61521.1 - 0.013 15.6 0.1 0.037 14.1 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KIR61521.1 - 0.016 15.0 0.2 0.041 13.7 0.0 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KIR61521.1 - 0.05 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 KIR61521.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.7 1 1 0 1 1 1 0 HTH DNA binding domain HTH_11 PF08279.12 KIR61521.1 - 0.15 12.0 0.5 0.72 9.8 0.1 2.2 2 0 0 2 2 2 0 HTH domain HTH_30 PF13556.6 KIR61522.1 - 8e-19 67.2 3.2 1.7e-18 66.2 1.6 2.4 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 KIR61522.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_8 PF02954.19 KIR61522.1 - 0.25 11.1 4.1 1.1 9.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family FAD_binding_6 PF00970.24 KIR61523.1 - 3.2e-10 40.2 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 KIR61523.1 - 1.5e-06 28.0 0.4 2.5e-06 27.3 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 KIR61523.1 - 1.8e-06 28.5 0.0 3.8e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 KIR61523.1 - 0.085 12.7 1.0 0.18 11.6 1.0 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B DUF3658 PF12395.8 KIR61523.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function FA_desaturase PF00487.24 KIR61524.1 - 7.8e-28 98.0 7.4 1e-27 97.6 7.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Spermine_synth PF01564.17 KIR61525.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Spermine/spermidine synthase domain DUF4180 PF13788.6 KIR61526.1 - 3.3e-39 133.3 0.0 3.7e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4180) HTH_17 PF12728.7 KIR61527.1 - 5.7e-16 58.4 0.2 1.2e-15 57.5 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 KIR61527.1 - 4.6e-05 23.1 1.0 8.5e-05 22.2 1.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_23 PF13384.6 KIR61527.1 - 0.0021 17.8 0.1 0.0081 15.9 0.0 2.1 2 1 0 2 2 2 1 Homeodomain-like domain MerR_1 PF13411.6 KIR61527.1 - 0.0027 17.8 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_29 PF13551.6 KIR61527.1 - 0.0058 16.6 0.5 0.22 11.6 0.1 2.5 1 1 1 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KIR61527.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 KIR61527.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix His_Phos_1 PF00300.22 KIR61528.1 - 5.2e-28 98.1 1.1 6.3e-28 97.8 1.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Trns_repr_metal PF02583.17 KIR61529.1 - 2.1e-21 76.0 0.2 2.4e-21 75.9 0.2 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor T7SS_ESX1_EccB PF05108.13 KIR61530.1 - 1e-80 271.7 8.5 1.1e-80 271.6 8.5 1.0 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B Methyltransf_25 PF13649.6 KIR61531.1 - 1e-12 48.6 0.1 2e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61531.1 - 3.1e-09 37.4 0.1 5.1e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR61531.1 - 1.9e-08 34.3 0.0 5.1e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61531.1 - 9.5e-08 32.7 0.0 2.6e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR61531.1 - 5.8e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIR61531.1 - 0.00032 20.2 0.1 0.00035 20.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 KIR61531.1 - 0.00046 19.7 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 KIR61531.1 - 0.00096 18.7 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KIR61531.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TPMT PF05724.11 KIR61531.1 - 0.011 15.4 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KIR61531.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KIR61531.1 - 0.057 12.8 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB N6_N4_Mtase PF01555.18 KIR61531.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 DNA methylase PCMT PF01135.19 KIR61531.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AP_endonuc_2 PF01261.24 KIR61532.1 - 2.5e-28 99.0 0.1 3.5e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 KIR61532.1 - 0.05 13.3 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus DUF2561 PF10812.8 KIR61532.1 - 0.058 13.4 0.8 0.9 9.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) Glyco_hydro_63 PF03200.16 KIR61533.1 - 0.0047 15.7 5.0 0.056 12.2 0.4 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain CBS PF00571.28 KIR61534.1 - 5.4e-26 90.8 7.9 6.9e-16 58.4 0.2 2.9 3 0 0 3 3 3 2 CBS domain BON PF04972.17 KIR61534.1 - 1.2e-10 41.5 4.1 3.2e-10 40.2 4.1 1.7 1 0 0 1 1 1 1 BON domain sCache_3_2 PF17203.4 KIR61534.1 - 0.0012 19.0 4.4 0.024 14.8 0.4 2.7 3 0 0 3 3 3 2 Single cache domain 3 UPF0016 PF01169.19 KIR61534.1 - 0.073 13.4 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 LMWPc PF01451.21 KIR61535.1 - 1.7e-23 83.5 0.0 2.2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DinB_2 PF12867.7 KIR61535.1 - 0.058 13.9 0.5 0.74 10.3 0.5 2.0 1 1 0 1 1 1 0 DinB superfamily SBF PF01758.16 KIR61536.1 - 1.3e-59 201.1 2.2 1.3e-59 201.1 2.2 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family Kinocilin PF15033.6 KIR61536.1 - 0.0099 15.5 0.4 0.026 14.1 0.4 1.7 1 0 0 1 1 1 1 Kinocilin protein HTH_5 PF01022.20 KIR61537.1 - 9.2e-16 57.5 0.0 2e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR61537.1 - 2.9e-13 49.6 0.4 4.7e-12 45.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR61537.1 - 0.0015 18.4 0.3 0.0071 16.2 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 KIR61537.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Pyr_redox_3 PF13738.6 KIR61538.1 - 1.7e-17 63.6 0.0 2.1e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR61538.1 - 5.6e-13 48.8 0.1 2.3e-12 46.8 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR61538.1 - 7.7e-10 38.9 9.2 5.4e-09 36.1 8.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIR61538.1 - 1.6e-09 37.4 0.0 0.025 13.7 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIR61538.1 - 3.8e-07 30.2 1.7 2.1e-06 27.8 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR61538.1 - 4.3e-07 29.4 1.0 4.3e-07 29.4 1.0 2.0 1 1 2 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KIR61538.1 - 7.1e-06 25.3 0.5 0.0035 16.4 0.2 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 KIR61538.1 - 1e-05 25.0 2.2 0.00014 21.2 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIR61538.1 - 2.9e-05 23.0 0.2 0.0001 21.2 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KIR61538.1 - 3.9e-05 24.1 0.6 0.011 16.2 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIR61538.1 - 0.00028 20.3 3.5 0.0043 16.4 0.8 2.9 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KIR61538.1 - 0.00069 18.9 0.0 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KIR61538.1 - 0.00077 19.5 7.2 1.1 9.3 0.4 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KIR61538.1 - 0.00095 19.6 0.0 0.86 10.1 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIR61538.1 - 0.069 13.2 0.1 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KIR61538.1 - 0.096 11.8 0.9 0.62 9.1 1.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KIR61538.1 - 0.19 12.0 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain DUF2530 PF10745.9 KIR61539.1 - 4 7.7 17.8 1.7 8.9 3.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2530) DUF456 PF04306.13 KIR61539.1 - 5.4 7.3 29.3 6 7.2 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF456) VirB3 PF05101.13 KIR61539.1 - 9.5 6.5 19.1 12 6.3 2.8 3.5 1 1 2 3 3 3 0 Type IV secretory pathway, VirB3-like protein FGE-sulfatase PF03781.16 KIR61540.1 - 0.0064 16.1 0.0 0.027 14.1 0.1 1.8 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Macro PF01661.21 KIR61541.1 - 0.00032 20.7 0.0 0.00044 20.3 0.0 1.2 1 0 0 1 1 1 1 Macro domain Response_reg PF00072.24 KIR61542.1 - 7.4e-23 80.9 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR61542.1 - 1.1e-12 47.3 0.0 1.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 KIR61542.1 - 8.6e-07 28.6 0.1 2.7e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR61542.1 - 9.4e-06 25.2 0.1 2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KIR61542.1 - 4.6e-05 22.7 0.3 0.00011 21.5 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 KIR61542.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 KIR61542.1 - 0.00033 21.1 0.1 0.00067 20.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KIR61542.1 - 0.0023 18.0 0.2 0.0023 18.0 0.2 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR61542.1 - 0.0024 17.9 1.4 0.0074 16.3 0.2 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 KIR61542.1 - 0.0029 17.3 0.9 0.0048 16.6 0.1 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_10 PF04967.12 KIR61542.1 - 0.0046 16.7 0.6 0.039 13.8 0.6 2.4 1 1 0 1 1 1 1 HTH DNA binding domain HTH_11 PF08279.12 KIR61542.1 - 0.0052 16.7 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 KIR61542.1 - 0.0067 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR61542.1 - 0.0072 16.1 0.2 0.0072 16.1 0.2 2.6 4 0 0 4 4 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR61542.1 - 0.011 15.6 0.1 0.031 14.2 0.1 1.8 1 0 0 1 1 1 0 MarR family MerR PF00376.23 KIR61542.1 - 0.032 14.0 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_5 PF01022.20 KIR61542.1 - 0.04 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 KIR61542.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Mga PF08280.11 KIR61542.1 - 0.061 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_17 PF12728.7 KIR61542.1 - 0.068 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3489 PF11994.8 KIR61542.1 - 0.096 12.8 0.2 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) HTH_31 PF13560.6 KIR61542.1 - 0.95 9.9 9.9 0.41 11.0 5.6 2.8 2 2 0 2 2 2 0 Helix-turn-helix domain DUF397 PF04149.12 KIR61544.1 - 7.5e-22 77.1 0.2 8.3e-22 77.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) AMP-binding PF00501.28 KIR61545.1 - 8e-75 252.0 0.1 1.3e-74 251.3 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KIR61545.1 - 3.7e-60 203.6 0.2 9e-60 202.4 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIR61545.1 - 2.5e-38 130.7 1.0 2.5e-38 130.7 1.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR61545.1 - 1.1e-19 70.9 0.0 2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR61545.1 - 8.2e-11 42.1 0.2 3.6e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR61545.1 - 8.9e-10 39.4 0.1 5e-09 37.0 0.1 2.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 KIR61545.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Alpha-E PF04168.12 KIR61545.1 - 0.17 11.6 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. SelB-wing_2 PF09106.11 KIR61545.1 - 0.19 12.0 1.3 1.6 9.0 0.1 2.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix AMP-binding PF00501.28 KIR61546.1 - 2.6e-93 312.9 0.0 6.1e-93 311.7 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR61546.1 - 1.9e-77 260.9 0.0 2.7e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KIR61546.1 - 7.5e-29 99.9 0.0 6.2e-13 48.9 0.0 3.5 4 0 0 4 4 4 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR61546.1 - 3.4e-07 31.1 0.9 1.7e-06 28.9 0.9 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chlorosome_CsmC PF11098.8 KIR61546.1 - 0.53 10.3 2.1 0.81 9.7 0.2 2.1 2 0 0 2 2 2 0 Chlorosome envelope protein C TauD PF02668.16 KIR61547.1 - 1.4e-42 146.4 0.3 1.7e-42 146.1 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TOM6p PF15184.6 KIR61547.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog MbtH PF03621.13 KIR61548.1 - 2.6e-20 71.6 0.0 3.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 MbtH-like protein AMP-binding PF00501.28 KIR61549.1 - 9.5e-89 297.9 0.1 1.5e-88 297.3 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR61549.1 - 2.6e-79 267.1 0.0 7.9e-79 265.5 0.0 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KIR61549.1 - 5.4e-11 42.7 0.1 2.3e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR61549.1 - 3.4e-09 37.6 4.1 4.2e-09 37.2 0.1 3.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AATase PF07247.12 KIR61549.1 - 0.16 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase Condensation PF00668.20 KIR61550.1 - 5.8e-108 361.5 0.0 7.8e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KIR61550.1 - 2.6e-88 296.4 1.0 1.2e-87 294.3 1.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 KIR61550.1 - 1e-20 74.0 44.6 1e-20 74.0 44.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding_C PF13193.6 KIR61550.1 - 1.6e-13 51.4 0.3 1e-12 48.8 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR61550.1 - 2.5e-13 50.2 0.0 1.1e-12 48.1 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.20 KIR61550.1 - 4.6e-13 49.8 0.0 1.2e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain MFS_3 PF05977.13 KIR61550.1 - 7.1e-13 47.8 38.7 1.3e-12 47.0 38.7 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector ATG22 PF11700.8 KIR61550.1 - 0.0021 16.7 2.9 0.0021 16.7 2.9 1.4 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KIR61550.1 - 0.017 14.0 2.5 0.042 12.7 2.5 1.6 1 0 0 1 1 1 0 MFS_1 like family MarR_2 PF12802.7 KIR61551.1 - 0.1 12.5 1.6 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 MarR family PemK_toxin PF02452.17 KIR61552.1 - 2.6e-10 40.7 0.0 3.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system GGDEF PF00990.21 KIR61553.1 - 3.4e-37 127.7 0.0 4.5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain LapA_dom PF06305.11 KIR61553.1 - 0.051 13.4 0.5 0.087 12.6 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain IGF2_C PF08365.11 KIR61553.1 - 0.22 11.6 1.1 0.56 10.3 1.1 1.8 1 1 0 1 1 1 0 Insulin-like growth factor II E-peptide DUF397 PF04149.12 KIR61554.1 - 1.4e-17 63.5 0.0 1.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Methyltransf_19 PF04672.12 KIR61555.1 - 5e-109 363.9 0.6 5.6e-109 363.8 0.6 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_31 PF13847.6 KIR61555.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61555.1 - 0.018 15.7 0.0 0.047 14.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61555.1 - 0.11 13.2 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.11 KIR61556.1 - 2e-22 79.9 6.5 2e-22 79.9 6.5 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1129 PF06570.11 KIR61556.1 - 0.59 9.6 2.9 1 8.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Yip1 PF04893.17 KIR61556.1 - 2.3 7.9 12.7 0.87 9.3 1.2 2.2 2 0 0 2 2 2 0 Yip1 domain RseC_MucC PF04246.12 KIR61556.1 - 4.7 7.2 7.5 12 5.8 0.9 2.5 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4381 PF14316.6 KIR61556.1 - 8.9 6.5 5.7 34 4.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Pirin PF02678.16 KIR61558.1 - 8.8e-31 106.1 0.1 1.4e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KIR61558.1 - 1.3e-20 73.7 0.0 5.3e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KIR61558.1 - 0.074 12.8 0.4 0.16 11.7 0.4 1.5 1 0 0 1 1 1 0 Cupin domain DUF1345 PF07077.11 KIR61560.1 - 1.7e-54 184.1 0.1 2.2e-54 183.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) DUF2795 PF11387.8 KIR61561.1 - 2.3e-14 53.3 1.1 4.9e-14 52.2 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) DUF2267 PF10025.9 KIR61562.1 - 4.3e-32 110.9 5.0 4.9e-32 110.8 5.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) Bac_DNA_binding PF00216.21 KIR61562.1 - 0.00091 19.4 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial DNA-binding protein HU-CCDC81_euk_2 PF18289.1 KIR61562.1 - 0.054 13.6 0.2 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 CoA_transf_3 PF02515.17 KIR61563.1 - 1.4e-84 284.4 0.1 1.6e-84 284.1 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III TerC PF03741.16 KIR61564.1 - 1.6e-45 155.0 14.7 1.6e-45 155.0 14.7 2.1 3 0 0 3 3 3 1 Integral membrane protein TerC family Oxidored_molyb PF00174.19 KIR61565.1 - 2.5e-26 92.3 0.1 3.2e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.21 KIR61566.1 - 2.5e-13 50.6 0.0 3.4e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIR61566.1 - 1.2e-10 41.6 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIR61566.1 - 0.18 11.9 0.3 3.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HypA PF01155.19 KIR61567.1 - 0.0039 17.2 0.0 0.0047 16.9 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 KIR61567.1 - 0.15 11.9 1.0 14 5.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 KIR61567.1 - 0.31 11.2 2.0 9.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Rubredoxin_2 PF18073.1 KIR61567.1 - 0.64 9.8 3.5 7 6.5 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain FAD_binding_3 PF01494.19 KIR61568.1 - 6.3e-08 32.3 0.0 1.5e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIR61568.1 - 0.00016 20.9 0.6 0.019 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIR61568.1 - 0.00016 21.0 0.0 0.045 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIR61568.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 KIR61568.1 - 0.065 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIR61568.1 - 0.08 13.5 0.0 0.69 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactate_perm PF02652.14 KIR61569.1 - 3.5e-120 402.2 25.2 6.4e-120 401.3 25.2 1.4 1 1 0 1 1 1 1 L-lactate permease DUF3377 PF11857.8 KIR61569.1 - 0.51 10.3 2.7 2.1 8.3 2.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pyr_redox_2 PF07992.14 KIR61570.1 - 1.9e-59 201.3 0.0 2.3e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR61570.1 - 1.9e-10 41.1 2.0 1.3e-05 25.7 0.6 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIR61570.1 - 2.5e-05 24.3 0.2 0.41 10.6 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIR61570.1 - 0.00045 19.2 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Rossmann-like PF10727.9 KIR61570.1 - 0.01 15.7 0.4 0.48 10.3 0.0 3.1 3 1 0 3 3 3 0 Rossmann-like domain NAD_binding_8 PF13450.6 KIR61570.1 - 0.011 16.0 2.1 0.045 14.0 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIR61570.1 - 0.011 14.8 2.3 0.057 12.5 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIR61570.1 - 0.026 13.8 0.1 0.26 10.6 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KIR61570.1 - 0.041 13.9 0.0 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KIR61570.1 - 0.093 11.9 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIR61570.1 - 0.13 11.8 8.4 1.6 8.3 0.0 3.8 3 1 0 4 4 4 0 FAD dependent oxidoreductase Methyltransf_11 PF08241.12 KIR61571.1 - 0.00057 20.5 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61571.1 - 0.0062 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 KIR61571.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Response_reg PF00072.24 KIR61571.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain Beta-lactamase2 PF13354.6 KIR61572.1 - 1.3e-35 122.9 0.3 1.6e-35 122.6 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KIR61572.1 - 6.2e-30 104.6 9.3 2.1e-29 102.8 9.3 1.7 1 1 0 1 1 1 1 Beta-lactamase B12-binding PF02310.19 KIR61573.1 - 2.4e-15 56.7 0.1 4.9e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KIR61573.1 - 9.3e-11 42.0 0.6 2e-10 40.9 0.6 1.5 1 0 0 1 1 1 1 B12 binding domain STAS_2 PF13466.6 KIR61574.1 - 3.5e-17 62.5 4.4 4.2e-17 62.3 4.4 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KIR61574.1 - 1.6e-11 43.9 0.0 1.7e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 STAS domain Response_reg PF00072.24 KIR61575.1 - 6.4e-22 77.8 1.5 7.7e-22 77.6 1.5 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DivIVA PF05103.13 KIR61576.1 - 0.0056 16.8 0.5 0.24 11.5 0.0 2.2 2 0 0 2 2 2 2 DivIVA protein ATP-synt_B PF00430.18 KIR61576.1 - 0.13 12.4 7.5 0.22 11.6 7.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) OsmC PF02566.19 KIR61577.1 - 1.3e-10 41.7 0.0 1.7e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Pkinase PF00069.25 KIR61578.1 - 9.4e-42 143.2 0.0 1.2e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR61578.1 - 5.9e-25 88.0 0.0 7.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR61578.1 - 1.1e-08 35.3 5.1 0.00011 22.2 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR61578.1 - 0.047 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Response_reg PF00072.24 KIR61579.1 - 5.4e-29 100.6 0.0 9.8e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR61579.1 - 1.2e-27 95.8 0.1 1.4e-25 89.1 0.0 2.4 2 0 0 2 2 2 2 Transcriptional regulatory protein, C terminal FleQ PF06490.11 KIR61579.1 - 0.003 17.9 0.0 0.0046 17.3 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ DUF2220 PF09983.9 KIR61579.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) HATPase_c PF02518.26 KIR61580.1 - 5.8e-24 84.8 0.0 9.3e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR61580.1 - 3e-19 68.8 0.9 5.4e-19 68.0 0.3 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR61580.1 - 9.1e-09 35.6 0.8 3.6e-08 33.7 0.8 2.2 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 KIR61580.1 - 5.2e-05 23.2 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR61580.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KIR61580.1 - 0.29 11.1 0.0 0.5 10.3 0.0 1.4 1 1 0 1 1 1 0 GHKL domain PMT_2 PF13231.6 KIR61581.1 - 2.6e-29 102.5 18.6 2.6e-29 102.5 18.6 3.8 3 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Na_Pi_cotrans PF02690.15 KIR61581.1 - 3.6 7.7 9.1 3.5 7.7 3.4 2.7 2 1 0 2 2 2 0 Na+/Pi-cotransporter NMT1_2 PF13379.6 KIR61582.1 - 2.4e-19 70.1 0.1 6.9e-19 68.5 0.1 1.7 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KIR61582.1 - 8.5e-19 68.4 0.1 1.3e-18 67.8 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 KIR61582.1 - 4.1e-09 36.3 0.1 6.1e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 KIR61582.1 - 1.1e-08 34.7 0.1 1.8e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 KIR61582.1 - 8.5e-06 25.5 0.3 1.3e-05 24.9 0.3 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 KIR61582.1 - 0.0038 16.4 0.1 0.0058 15.8 0.1 1.2 1 0 0 1 1 1 1 PBP superfamily domain LysR_substrate PF03466.20 KIR61582.1 - 0.022 14.1 0.0 0.53 9.6 0.0 2.1 1 1 1 2 2 2 0 LysR substrate binding domain ABC_tran PF00005.27 KIR61583.1 - 4.1e-24 85.7 0.0 6.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR61583.1 - 3e-09 37.1 0.1 0.0017 18.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR61583.1 - 0.0005 20.5 0.4 0.0012 19.3 0.2 1.8 1 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR61583.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIR61583.1 - 0.0029 17.9 0.3 0.011 16.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIR61583.1 - 0.0031 18.0 1.7 1.6 9.2 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIR61583.1 - 0.005 17.1 0.4 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR61583.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KIR61583.1 - 0.035 13.5 0.1 1 8.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KIR61583.1 - 0.068 13.7 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIR61583.1 - 0.072 13.0 0.0 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 KIR61583.1 - 0.094 12.4 0.0 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KIR61583.1 - 0.094 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 KIR61583.1 - 0.23 10.6 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIR61583.1 - 0.25 11.2 2.7 0.47 10.3 0.2 2.4 3 0 0 3 3 3 0 NACHT domain Polysacc_deac_1 PF01522.21 KIR61584.1 - 5.4e-13 48.9 0.0 9.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase MmgE_PrpD PF03972.14 KIR61585.1 - 1e-45 156.1 22.1 1.4e-45 155.7 22.1 1.2 1 0 0 1 1 1 1 MmgE/PrpD family Asparaginase PF00710.20 KIR61586.1 - 9.4e-42 142.7 0.0 1.7e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KIR61586.1 - 1.3e-25 89.8 1.0 2.3e-25 89.0 0.3 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain PA PF02225.22 KIR61586.1 - 0.044 13.8 3.1 1.2 9.3 1.5 2.5 2 1 0 2 2 2 0 PA domain Gly_reductase PF09338.11 KIR61586.1 - 0.21 9.9 0.1 1.6 7.0 0.0 2.1 3 0 0 3 3 3 0 Glycine/sarcosine/betaine reductase component B subunits Glyoxalase PF00903.25 KIR61587.1 - 2.3e-08 34.3 0.0 3.8e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR61587.1 - 7.3e-05 23.5 0.6 9.2e-05 23.2 0.6 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KIR61587.1 - 0.035 14.0 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain 3-dmu-9_3-mt PF06983.13 KIR61587.1 - 0.11 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase Methyltransf_23 PF13489.6 KIR61588.1 - 4e-07 30.0 0.0 7.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61588.1 - 2.7e-05 24.8 0.0 6.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61588.1 - 0.00027 21.5 0.2 0.0014 19.2 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61588.1 - 0.0041 17.8 0.1 0.015 16.0 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_19 PF04672.12 KIR61588.1 - 1.1 8.6 4.8 0.79 9.2 0.2 2.5 2 1 1 3 3 3 0 S-adenosyl methyltransferase Sulfatase PF00884.23 KIR61589.1 - 5.7e-21 75.2 0.0 7.5e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 KIR61589.1 - 1.8e-08 34.4 0.0 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KIR61589.1 - 0.044 12.4 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Citrate_synt PF00285.21 KIR61590.1 - 3e-133 444.4 0.0 3.5e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Mlf1IP PF10248.9 KIR61590.1 - 0.025 14.6 0.0 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Glycos_transf_1 PF00534.20 KIR61591.1 - 3.3e-36 124.4 0.0 5.5e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR61591.1 - 3.6e-34 118.2 5.0 8e-34 117.1 5.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIR61591.1 - 8.8e-30 104.3 11.1 8.8e-30 104.3 11.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KIR61591.1 - 4.5e-28 98.4 0.8 1.9e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIR61591.1 - 1.1e-20 74.4 8.5 8.2e-20 71.5 3.8 2.7 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 KIR61591.1 - 2.3e-14 53.5 0.0 6.2e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR61591.1 - 0.0001 22.3 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like CBM_48 PF02922.18 KIR61592.1 - 5.4e-20 71.5 0.1 1.7e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KIR61592.1 - 1.8e-14 54.0 0.0 7.6e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Pur_ac_phosph_N PF16656.5 KIR61592.1 - 0.11 13.0 0.0 1 10.0 0.0 2.4 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Alpha-amylase PF00128.24 KIR61593.1 - 3.9e-18 66.1 0.0 1.7e-15 57.4 0.0 2.8 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase PF00128.24 KIR61594.1 - 1.9e-19 70.4 0.0 8.7e-12 45.2 0.0 3.0 2 1 1 3 3 3 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 KIR61594.1 - 9.1e-16 58.0 2.0 1.5e-15 57.2 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) CBM_48 PF02922.18 KIR61594.1 - 3.8e-05 24.0 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL10 PF02638.15 KIR61594.1 - 0.16 11.1 0.1 0.36 9.9 0.1 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase-like 10 GntR PF00392.21 KIR61595.1 - 8.3e-18 63.8 0.2 9.2e-18 63.7 0.2 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 KIR61595.1 - 5.7e-05 22.7 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KIR61595.1 - 6.3e-05 22.8 0.0 7.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 HTH domain HTH_36 PF13730.6 KIR61595.1 - 0.00041 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR61595.1 - 0.0054 16.6 0.5 0.0085 16.0 0.4 1.4 1 1 0 1 1 1 1 MarR family Prot_ATP_ID_OB PF16450.5 KIR61595.1 - 0.01 15.8 0.4 1.2 9.2 0.1 2.1 1 1 1 2 2 2 1 Proteasomal ATPase OB C-terminal domain Rrf2 PF02082.20 KIR61595.1 - 0.013 15.9 0.1 0.014 15.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 KIR61595.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KIR61595.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RP-C PF03428.13 KIR61595.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_Crp_2 PF13545.6 KIR61595.1 - 0.048 13.6 0.4 0.052 13.5 0.4 1.3 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain AbiEi_4 PF13338.6 KIR61595.1 - 0.069 13.3 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_28 PF13518.6 KIR61595.1 - 0.099 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 KIR61595.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KIR61596.1 - 1.1e-12 48.1 4.8 1.1e-12 48.1 4.8 4.3 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61596.1 - 0.0052 16.8 0.2 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR61596.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Pentapeptide_3 PF13576.6 KIR61597.1 - 8.4e-26 89.9 39.3 1.8e-09 37.6 6.9 7.0 3 3 5 8 8 8 5 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KIR61597.1 - 4.6e-06 26.2 15.3 0.0015 18.1 1.2 5.0 4 3 1 5 5 5 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KIR61597.1 - 9.6e-05 22.5 0.6 1.2 9.4 0.0 3.4 2 2 1 3 3 3 2 Pentapeptide repeats (9 copies) HEAT_2 PF13646.6 KIR61597.1 - 0.049 14.0 7.9 0.081 13.3 0.3 3.1 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.22 KIR61597.1 - 0.12 12.6 1.8 1.1 9.7 0.0 3.2 2 2 1 3 3 3 0 HEAT repeat GCS2 PF04107.13 KIR61598.1 - 6.4e-07 29.0 1.3 0.021 14.2 0.1 2.5 2 1 0 2 2 2 2 Glutamate-cysteine ligase family 2(GCS2) TMEM239 PF15841.5 KIR61599.1 - 0.91 9.4 5.7 0.62 9.9 3.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 239 family baeRF_family2 PF18844.1 KIR61600.1 - 2.3e-35 121.8 16.1 6.2e-35 120.5 16.1 1.7 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 baeRF_family10 PF18854.1 KIR61600.1 - 1.4e-16 61.0 7.3 3.7e-16 59.6 7.3 1.8 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KIR61600.1 - 5.9e-14 52.5 10.2 5.9e-14 52.5 10.2 2.6 2 1 1 3 3 3 1 Actinobacteria/chloroflexi VLRF1 release factor PALP PF00291.25 KIR61600.1 - 0.0074 15.7 1.5 0.014 14.8 1.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LPD22 PF18834.1 KIR61600.1 - 0.19 11.9 3.4 0.22 11.8 0.9 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 TPP_enzyme_N PF02776.18 KIR61601.1 - 4.2e-37 127.4 0.9 6.7e-37 126.7 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIR61601.1 - 4e-28 97.8 0.5 1.2e-27 96.3 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIR61601.1 - 7.8e-20 71.2 0.0 3.6e-19 69.0 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HRDC PF00570.23 KIR61601.1 - 0.23 11.5 2.6 0.3 11.1 0.1 2.3 2 0 0 2 2 2 0 HRDC domain Sigma70_r4 PF04545.16 KIR61603.1 - 9.7e-18 63.4 1.8 1.4e-16 59.7 0.4 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR61603.1 - 1.1e-16 60.4 2.1 2.2e-16 59.3 0.2 2.6 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 KIR61603.1 - 1.4e-14 53.9 0.0 3e-12 46.5 0.2 2.2 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 KIR61603.1 - 3.6e-10 39.4 2.7 1.1e-09 37.8 0.0 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 MarR_2 PF12802.7 KIR61603.1 - 0.0001 22.1 0.8 0.023 14.6 0.1 2.9 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KIR61603.1 - 0.00047 19.9 0.6 0.00047 19.9 0.6 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_ECF PF07638.11 KIR61603.1 - 0.00066 19.6 0.1 0.0017 18.3 0.0 1.7 2 0 0 2 2 2 1 ECF sigma factor HTH_Tnp_4 PF13613.6 KIR61603.1 - 0.0046 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 KIR61603.1 - 0.0049 16.8 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 MarR family IF2_N PF04760.15 KIR61603.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region HTH_24 PF13412.6 KIR61603.1 - 0.012 15.2 0.1 0.15 11.7 0.0 2.6 2 1 1 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KIR61603.1 - 0.019 14.9 3.7 0.032 14.2 0.1 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KIR61603.1 - 0.019 15.1 0.2 0.019 15.1 0.2 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_10 PF04967.12 KIR61603.1 - 0.071 12.9 0.3 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_3 PF01381.22 KIR61603.1 - 0.071 13.2 0.2 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_37 PF13744.6 KIR61603.1 - 0.11 12.4 0.6 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain COX1 PF00115.20 KIR61604.1 - 7.6e-152 506.1 61.9 8.9e-152 505.9 61.9 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I p53-inducible11 PF14936.6 KIR61604.1 - 0.16 12.0 3.4 11 6.1 0.4 2.5 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 STAS_2 PF13466.6 KIR61605.1 - 1.5e-06 28.4 5.7 1.5e-06 28.4 5.7 2.5 2 0 0 2 2 2 1 STAS domain HATPase_c_2 PF13581.6 KIR61605.1 - 2.5e-06 27.4 0.7 7.1e-06 26.0 0.1 2.1 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain STAS PF01740.21 KIR61605.1 - 0.00043 19.9 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 STAS domain Glycos_transf_1 PF00534.20 KIR61606.1 - 2.8e-14 53.0 0.0 7.9e-14 51.6 0.0 1.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR61606.1 - 5.5e-14 52.7 0.1 8.7e-13 48.9 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR61606.1 - 2.2e-10 40.8 2.1 1.4e-09 38.2 1.3 2.5 2 1 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIR61606.1 - 3.7e-05 24.0 0.0 8.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR61606.1 - 0.0053 17.2 11.3 0.0053 17.2 11.3 3.2 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_2 PF00535.26 KIR61607.1 - 1.3e-14 54.4 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR61607.1 - 2.2e-08 34.3 0.1 3.6e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Osmo_MPGsynth PF09488.10 KIR61607.1 - 0.0015 17.3 0.0 0.012 14.3 0.0 2.2 1 1 1 2 2 2 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Glyco_tranf_2_2 PF10111.9 KIR61607.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ADH_zinc_N PF00107.26 KIR61608.1 - 3.8e-12 46.3 0.0 6.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIR61608.1 - 3.4e-05 23.7 0.1 0.092 12.7 0.0 2.6 2 0 0 2 2 2 2 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 KIR61608.1 - 0.005 16.2 1.0 0.012 14.9 1.0 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KIR61608.1 - 0.0062 17.6 0.0 0.018 16.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAO PF01266.24 KIR61608.1 - 0.013 15.1 1.5 0.025 14.1 1.5 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR61608.1 - 0.018 14.2 0.4 0.03 13.4 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KIR61608.1 - 0.062 12.5 0.2 0.099 11.9 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR61608.1 - 0.079 13.2 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Methyltransf_24 PF13578.6 KIR61608.1 - 0.086 13.9 0.0 0.59 11.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KIR61608.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KIR61608.1 - 0.17 11.5 0.3 0.3 10.8 0.1 1.4 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SecA_DEAD PF07517.14 KIR61609.1 - 1.1e-81 274.3 0.0 2.3e-81 273.3 0.0 1.5 1 1 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 KIR61609.1 - 1.1e-24 87.2 0.0 2.6e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SecA_SW PF07516.13 KIR61609.1 - 2.9e-22 79.7 0.4 6e-14 52.6 0.0 2.3 1 1 1 2 2 2 2 SecA Wing and Scaffold domain DUF2231 PF09990.9 KIR61610.1 - 2.6e-10 40.6 6.0 3.7e-10 40.1 6.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) Methyltransf_11 PF08241.12 KIR61611.1 - 1.5e-07 31.9 0.0 4.2e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61611.1 - 8e-05 23.3 0.0 0.0002 22.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF3500 PF12006.8 KIR61612.1 - 1.3e-80 271.1 0.0 1.5e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Cupin_6 PF12852.7 KIR61613.1 - 0.023 14.4 0.4 0.025 14.3 0.4 1.1 1 0 0 1 1 1 0 Cupin CDO_I PF05995.12 KIR61614.1 - 7.1e-24 84.0 0.4 4e-23 81.6 0.4 1.8 1 1 0 1 1 1 1 Cysteine dioxygenase type I Cupin_2 PF07883.11 KIR61614.1 - 7.9e-05 22.3 0.6 0.00014 21.5 0.6 1.4 1 0 0 1 1 1 1 Cupin domain Rhodanese PF00581.20 KIR61615.1 - 2.3e-08 34.5 0.0 3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Trans_reg_C PF00486.28 KIR61616.1 - 1.3e-23 82.8 0.3 3e-23 81.7 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 KIR61616.1 - 0.027 14.4 1.8 0.17 11.8 0.1 2.7 2 1 0 2 2 2 0 MarR family Trans_reg_C PF00486.28 KIR61617.1 - 3.8e-21 74.9 0.1 7.3e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal zf-dskA_traR PF01258.17 KIR61619.1 - 1.2e-08 34.8 2.4 1.9e-08 34.1 2.4 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger GPAT_N PF14829.6 KIR61619.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal FAM35_C PF15793.5 KIR61619.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein family FAM35, C-terminal DUF72 PF01904.18 KIR61620.1 - 1.8e-62 211.3 0.8 2e-62 211.2 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 DUF349 PF03993.12 KIR61621.1 - 0.017 15.4 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF4106 PF13388.6 KIR61621.1 - 0.044 13.0 0.7 0.042 13.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Metal_resist PF13801.6 KIR61621.1 - 0.092 12.9 10.3 0.11 12.7 10.3 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Cytochrom_C552 PF02335.15 KIR61621.1 - 0.12 11.3 1.3 0.13 11.2 1.3 1.0 1 0 0 1 1 1 0 Cytochrome c552 DUF3584 PF12128.8 KIR61621.1 - 0.19 9.2 2.9 0.21 9.1 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC2_membrane_2 PF12679.7 KIR61623.1 - 1.6e-06 27.7 16.2 2.3e-06 27.1 15.7 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR61623.1 - 1.6e-05 25.0 2.6 1.6e-05 25.0 2.6 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 KIR61624.1 - 4.3e-23 82.3 0.0 7.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR61624.1 - 3e-12 47.0 1.4 2.5e-07 30.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR61624.1 - 6.4e-05 23.5 0.0 9.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KIR61624.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KIR61624.1 - 0.003 18.0 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIR61624.1 - 0.0045 16.7 0.1 0.0096 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIR61624.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIR61624.1 - 0.051 13.8 0.3 0.29 11.4 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR61624.1 - 0.061 13.0 0.6 0.15 11.7 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIR61624.1 - 0.061 13.8 0.1 0.39 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KIR61624.1 - 0.082 12.3 0.1 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIR61624.1 - 0.23 11.0 0.4 0.44 10.1 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_2 PF12679.7 KIR61625.1 - 0.00015 21.1 15.8 0.0002 20.7 15.1 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 KIR61625.1 - 0.39 9.8 11.1 0.46 9.5 11.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 KIR61626.1 - 6.2e-29 101.2 0.0 8.3e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR61626.1 - 2.3e-12 47.3 3.7 2.7e-05 24.1 0.0 2.7 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR61626.1 - 0.00026 21.5 0.1 0.00037 21.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR61626.1 - 0.00079 19.1 0.3 0.0014 18.3 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 KIR61626.1 - 0.0013 17.8 0.4 0.0027 16.7 0.4 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KIR61626.1 - 0.009 16.3 0.0 0.041 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KIR61626.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KIR61626.1 - 0.022 14.5 0.1 0.032 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR61626.1 - 0.024 14.6 0.2 0.041 13.8 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 KIR61626.1 - 0.028 13.9 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIR61626.1 - 0.036 13.8 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KIR61626.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 KIR61626.1 - 0.077 13.1 0.1 0.26 11.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIR61626.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 KIR61626.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF2267 PF10025.9 KIR61628.1 - 3.9e-31 107.9 0.0 4.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) Glyco_hydro_10 PF00331.20 KIR61629.1 - 2.6e-115 384.9 0.0 3.1e-115 384.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_2 PF00553.19 KIR61629.1 - 5.8e-33 113.2 7.7 1.5e-32 111.9 7.7 1.7 1 0 0 1 1 1 1 Cellulose binding domain GYF_2 PF14237.6 KIR61629.1 - 0.15 11.9 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 GYF domain 2 Cupin_4 PF08007.12 KIR61631.1 - 5.5e-39 134.5 0.0 7.4e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 KIR61631.1 - 1e-12 48.3 0.1 2.8e-11 43.6 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 KIR61631.1 - 0.039 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Cupin Filament PF00038.21 KIR61632.1 - 0.0091 15.6 3.0 0.012 15.2 3.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein Polysacc_synt PF01943.17 KIR61632.1 - 0.037 13.4 0.4 0.048 13.0 0.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Apolipoprotein PF01442.18 KIR61632.1 - 0.52 10.2 13.7 1.1 9.1 13.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 KIR61632.1 - 0.84 10.2 7.6 1.1 9.7 7.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region FtsK_SpoIIIE PF01580.18 KIR61633.1 - 1.3e-19 70.5 0.0 7.1e-17 61.6 0.0 2.8 2 1 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 KIR61633.1 - 0.00024 21.4 0.0 0.00094 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61633.1 - 0.0027 18.1 0.2 0.0027 18.1 0.2 3.5 3 1 0 3 3 3 1 AAA ATPase domain TraG-D_C PF12696.7 KIR61633.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG AAA_11 PF13086.6 KIR61633.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain WXG100 PF06013.12 KIR61634.1 - 0.004 17.3 5.9 0.005 17.0 5.9 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF1090 PF06476.12 KIR61634.1 - 0.013 15.6 1.0 0.016 15.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) ABC_tran_CTD PF16326.5 KIR61634.1 - 0.46 10.8 7.2 8.9 6.6 7.2 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain PIN_9 PF18477.1 KIR61635.1 - 0.07 13.5 0.0 0.095 13.0 0.0 1.2 1 0 0 1 1 1 0 PIN like domain AAA_2 PF07724.14 KIR61636.1 - 1.3e-55 188.1 0.1 5.8e-54 182.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIR61636.1 - 1.1e-35 121.7 1.7 2.8e-35 120.4 1.7 1.7 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 KIR61636.1 - 5e-25 88.4 0.0 1.6e-13 51.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIR61636.1 - 1e-23 83.2 1.2 8.6e-23 80.2 0.2 3.0 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIR61636.1 - 1.2e-19 70.7 0.4 2.3e-13 50.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KIR61636.1 - 1.6e-14 53.7 7.6 2.2e-07 30.9 0.0 3.0 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 KIR61636.1 - 6.2e-09 36.5 20.8 4.1e-05 24.0 0.1 5.9 4 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KIR61636.1 - 2.1e-08 34.0 0.2 3e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain UVR PF02151.19 KIR61636.1 - 1.9e-07 30.6 9.1 1.9e-07 30.6 9.1 2.5 2 0 0 2 2 1 1 UvrB/uvrC motif AAA_22 PF13401.6 KIR61636.1 - 1.1e-06 29.0 9.8 0.0085 16.4 0.0 5.1 4 2 1 5 5 3 2 AAA domain ATPase_2 PF01637.18 KIR61636.1 - 3.9e-05 23.7 0.1 0.36 10.7 0.0 3.5 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIR61636.1 - 3.9e-05 23.7 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIR61636.1 - 6.3e-05 22.8 0.0 0.42 10.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_23 PF13476.6 KIR61636.1 - 8.7e-05 23.1 1.7 0.02 15.4 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KIR61636.1 - 9.1e-05 23.0 2.1 0.092 13.3 0.0 3.6 4 0 0 4 4 2 1 AAA domain TniB PF05621.11 KIR61636.1 - 0.00013 21.4 0.0 0.22 10.9 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 KIR61636.1 - 0.00073 19.5 0.0 0.39 10.6 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase NACHT PF05729.12 KIR61636.1 - 0.00081 19.4 0.0 0.087 12.7 0.0 3.0 3 0 0 3 3 2 1 NACHT domain TsaE PF02367.17 KIR61636.1 - 0.0011 18.9 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KIR61636.1 - 0.0023 18.1 0.0 0.76 10.0 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KIR61636.1 - 0.0026 18.1 0.1 4 7.9 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_7 PF12775.7 KIR61636.1 - 0.0027 17.3 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 KIR61636.1 - 0.0031 16.7 0.1 0.57 9.3 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 KIR61636.1 - 0.0033 17.2 5.5 1.6 8.4 0.0 4.2 3 2 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KIR61636.1 - 0.0041 16.4 0.1 0.12 11.6 0.0 3.1 3 1 1 4 4 3 1 Zeta toxin Mg_chelatase PF01078.21 KIR61636.1 - 0.005 16.2 0.2 17 4.7 0.0 3.5 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.6 KIR61636.1 - 0.0054 16.5 0.0 0.18 11.6 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 KIR61636.1 - 0.0068 16.3 0.1 0.5 10.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIR61636.1 - 0.0093 15.7 0.1 7.9 6.3 0.0 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIR61636.1 - 0.021 15.0 5.2 1.2 9.3 0.0 4.3 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 KIR61636.1 - 0.031 14.8 0.0 14 6.2 0.0 3.3 3 1 0 3 3 3 0 ABC transporter FlxA PF14282.6 KIR61636.1 - 0.082 12.9 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 FlxA-like protein AAA_24 PF13479.6 KIR61636.1 - 0.083 12.6 0.0 13 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KIR61636.1 - 0.099 12.4 3.0 5.6 6.7 0.0 4.0 3 1 1 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KIR61636.1 - 0.16 12.0 0.0 9.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF3140 PF11338.8 KIR61637.1 - 2.4e-22 79.1 0.0 2.9e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) LysR_substrate PF03466.20 KIR61639.1 - 2.5e-22 79.3 4.9 4.4e-22 78.5 4.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 KIR61639.1 - 3.6e-20 71.7 1.3 3.6e-20 71.7 1.3 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 KIR61639.1 - 0.00048 19.9 0.0 0.0015 18.3 0.1 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain TPR_14 PF13428.6 KIR61639.1 - 0.37 11.7 3.9 1.7 9.7 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Hemerythrin PF01814.23 KIR61640.1 - 5.5e-11 43.2 0.9 1.2e-10 42.1 0.9 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Peptidase_M20 PF01546.28 KIR61641.1 - 4.1e-39 134.4 0.0 6.9e-39 133.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIR61641.1 - 1.5e-14 53.8 0.1 4.2e-14 52.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIR61641.1 - 8e-08 32.2 0.0 1.4e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M28 Aldo_ket_red PF00248.21 KIR61643.1 - 8.7e-65 218.8 0.0 9.7e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_luciferase PF00296.20 KIR61644.1 - 8.8e-82 275.0 10.2 1e-81 274.8 10.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase XdhC_C PF13478.6 KIR61644.1 - 0.005 17.4 0.1 2.9 8.4 0.0 3.2 2 1 1 3 3 3 2 XdhC Rossmann domain BacA PF02673.18 KIR61645.1 - 2.3e-78 263.5 14.8 2.7e-78 263.3 14.8 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA DNA_processg_A PF02481.15 KIR61645.1 - 0.014 14.6 0.6 0.021 14.1 0.0 1.5 2 0 0 2 2 2 0 DNA recombination-mediator protein A His_Phos_1 PF00300.22 KIR61647.1 - 5.5e-47 160.0 0.0 6.4e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3090 PF11290.8 KIR61648.1 - 3e-69 232.2 0.1 3.4e-69 232.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3090) CENP-B_dimeris PF09026.10 KIR61648.1 - 0.012 16.0 5.6 0.02 15.3 5.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rad50_zn_hook PF04423.14 KIR61648.1 - 0.013 15.3 0.5 0.041 13.7 0.0 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif E7 PF00527.18 KIR61648.1 - 0.15 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 E7 protein, Early protein Sporozoite_P67 PF05642.11 KIR61648.1 - 0.38 8.8 2.0 0.57 8.2 2.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.6 KIR61648.1 - 1.3 9.3 8.6 1.5 9.1 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KIR61648.1 - 2.5 7.3 5.3 3.9 6.7 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KIR61648.1 - 3.6 5.6 4.8 4.6 5.2 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3_PI4_kinase PF00454.27 KIR61649.1 - 0.0094 15.8 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase tRNA-synt_1e PF01406.19 KIR61650.1 - 6.7e-80 268.7 0.0 8.3e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KIR61650.1 - 8e-06 24.8 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIR61650.1 - 2.8e-05 22.6 0.0 0.00014 20.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KIR61650.1 - 0.0086 15.0 0.0 2.9 6.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 KIR61650.1 - 0.26 10.6 0.1 0.45 9.8 0.0 1.4 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UTRA PF07702.13 KIR61651.1 - 1e-24 87.0 0.3 2e-24 86.0 0.3 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 KIR61651.1 - 2.7e-17 62.2 0.1 6.2e-17 61.0 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KIR61651.1 - 9e-05 22.3 0.1 0.00044 20.1 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 KIR61651.1 - 0.00027 21.0 0.1 0.00071 19.7 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR61651.1 - 0.00042 20.3 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIR61651.1 - 0.00054 19.7 0.0 0.0079 16.0 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_41 PF14502.6 KIR61651.1 - 0.0045 16.7 0.4 0.009 15.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR61651.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 KIR61651.1 - 0.0086 16.4 0.2 0.027 14.8 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator HTH_11 PF08279.12 KIR61651.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 KIR61651.1 - 0.017 14.6 0.0 0.079 12.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 TBPIP PF07106.13 KIR61651.1 - 0.042 13.8 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Fe_dep_repress PF01325.19 KIR61651.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 KIR61651.1 - 0.073 12.6 0.2 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KIR61651.1 - 0.2 11.5 2.2 0.47 10.3 0.0 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 KIR61651.1 - 0.2 11.6 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PAC2 PF09754.9 KIR61652.1 - 7.3e-54 183.0 0.0 8.9e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 PAC2 family TrbC_Ftype PF09673.10 KIR61652.1 - 0.086 12.9 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein ApbA PF02558.16 KIR61653.1 - 1.1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TetR_N PF00440.23 KIR61654.1 - 2.2e-10 40.2 0.4 8.1e-10 38.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KIR61654.1 - 0.0031 17.8 0.3 0.0077 16.5 0.3 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 KIR61654.1 - 0.03 14.4 0.1 0.073 13.2 0.1 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SATase_N PF06426.14 KIR61654.1 - 0.14 12.5 2.2 0.28 11.6 1.1 1.8 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal HTH_31 PF13560.6 KIR61655.1 - 3e-13 49.9 3.2 4.4e-13 49.4 3.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61655.1 - 7.3e-06 26.0 0.1 1.2e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR61655.1 - 2.9e-05 24.0 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR61655.1 - 0.02 14.7 1.2 0.12 12.2 0.5 2.2 1 1 1 2 2 2 0 Homeodomain-like domain KorB PF08535.10 KIR61655.1 - 0.052 13.6 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 KorB domain HTH_37 PF13744.6 KIR61655.1 - 0.065 13.2 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L32p PF01783.23 KIR61657.1 - 1e-22 80.1 8.6 1.1e-22 80.0 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family FeThRed_B PF02943.15 KIR61657.1 - 0.05 13.6 0.3 0.051 13.6 0.3 1.1 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain cobW PF02492.19 KIR61658.1 - 4e-54 182.9 0.1 5.1e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIR61658.1 - 1.9e-23 82.2 0.0 5.2e-23 80.8 0.0 1.8 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 KIR61658.1 - 0.0024 16.9 3.4 0.47 9.4 0.2 2.6 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KIR61658.1 - 0.013 15.4 0.1 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KIR61658.1 - 0.026 14.6 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KIR61658.1 - 0.072 13.5 0.2 0.2 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 KIR61658.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L31 PF01197.18 KIR61659.1 - 2.9e-29 101.1 0.0 3.3e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 CobW_C PF07683.14 KIR61660.1 - 2.2e-24 85.2 0.3 4.8e-23 80.9 0.1 2.9 2 1 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.19 KIR61660.1 - 3e-11 43.2 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L28 PF00830.19 KIR61661.1 - 1.4e-25 89.2 1.1 1.7e-25 88.9 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L28 family Ribosomal_L33 PF00471.20 KIR61662.1 - 1.9e-16 60.2 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Ribosomal_S14 PF00253.21 KIR61663.1 - 3.7e-24 84.2 0.6 6.8e-24 83.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Methyltransf_25 PF13649.6 KIR61664.1 - 3.2e-16 59.8 0.0 5.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61664.1 - 1.1e-14 54.8 0.1 1.7e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61664.1 - 4.4e-11 43.4 0.0 6.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR61664.1 - 2.2e-08 34.0 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR61664.1 - 5.6e-08 32.8 0.0 8.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR61664.1 - 3.6e-06 26.5 0.0 5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIR61664.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KIR61664.1 - 0.0027 17.5 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 KIR61664.1 - 0.0057 15.7 0.0 0.0078 15.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.17 KIR61664.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HTH_25 PF13413.6 KIR61664.1 - 0.18 11.7 0.1 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CMAS PF02353.20 KIR61664.1 - 0.18 11.1 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Na_Ca_ex PF01699.24 KIR61665.1 - 5.3e-27 94.6 35.6 6.2e-14 52.2 11.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zn_peptidase PF04228.13 KIR61666.1 - 6.7e-18 65.1 0.9 3.8e-16 59.4 0.9 2.2 1 1 0 1 1 1 1 Putative neutral zinc metallopeptidase Peptidase_M9 PF01752.17 KIR61666.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Collagenase HAD_2 PF13419.6 KIR61667.1 - 1e-26 94.1 0.0 1.2e-26 93.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR61667.1 - 2.6e-22 80.1 0.1 2e-21 77.3 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR61667.1 - 5.3e-17 62.8 0.1 6.4e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR61667.1 - 1e-06 28.7 0.3 1.4e-05 25.0 0.0 2.7 1 1 2 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIR61667.1 - 0.0003 20.8 0.0 0.33 11.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KIR61668.1 - 4.2e-37 127.9 63.7 1.1e-33 116.6 48.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIR61668.1 - 1.3e-06 28.0 48.9 1.5e-06 27.7 48.9 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KIR61668.1 - 9.3 5.0 32.4 0.77 8.6 14.6 2.7 2 2 0 2 2 2 0 Sugar (and other) transporter FtsX PF02687.21 KIR61669.1 - 2.9e-25 88.6 17.4 3.8e-14 52.9 3.4 5.5 6 1 0 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 KIR61669.1 - 1.1e-24 87.9 21.5 3.2e-14 53.7 6.0 5.0 4 1 1 5 5 5 3 MacB-like periplasmic core domain ABC_tran PF00005.27 KIR61670.1 - 2e-29 102.8 0.0 3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR61670.1 - 1.1e-06 28.3 0.0 0.019 14.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIR61670.1 - 1.9e-05 24.7 0.0 0.0055 16.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR61670.1 - 3.3e-05 23.6 0.5 5.9e-05 22.7 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR61670.1 - 0.00051 20.0 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIR61670.1 - 0.00071 19.9 0.1 0.0071 16.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR61670.1 - 0.00094 19.7 0.0 0.0014 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61670.1 - 0.0052 17.2 0.1 0.0083 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KIR61670.1 - 0.0058 16.2 0.4 0.066 12.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIR61670.1 - 0.03 14.0 1.2 0.093 12.4 0.4 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 KIR61670.1 - 0.036 13.0 0.0 3.6 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.6 KIR61670.1 - 0.067 12.9 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR61670.1 - 0.072 13.3 0.2 0.52 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIR61670.1 - 0.079 13.0 0.2 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KIR61670.1 - 0.13 12.5 0.0 2.9 8.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 KIR61670.1 - 0.19 11.1 0.1 3.7 6.8 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 KIR61670.1 - 0.21 12.1 0.1 0.65 10.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIR61670.1 - 0.65 10.2 2.3 0.73 10.1 0.6 1.9 2 1 0 2 2 2 0 AAA domain Response_reg PF00072.24 KIR61671.1 - 6.8e-26 90.6 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR61671.1 - 9.5e-21 73.1 0.6 2.1e-20 72.0 0.6 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR61671.1 - 5.6e-10 38.7 0.4 1.2e-09 37.7 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR61671.1 - 5.8e-07 28.9 0.5 1.2e-06 27.9 0.5 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KIR61671.1 - 0.00038 20.1 0.1 0.00078 19.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 KIR61671.1 - 0.0021 18.0 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 KIR61671.1 - 0.0022 17.8 0.6 0.0071 16.1 0.2 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 KIR61671.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KIR61671.1 - 0.027 14.3 0.1 0.071 12.9 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 KIR61671.1 - 0.043 13.8 0.4 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 HTH domain HTH_10 PF04967.12 KIR61671.1 - 0.047 13.5 1.6 0.79 9.6 0.4 2.8 2 1 0 2 2 2 0 HTH DNA binding domain HTH_20 PF12840.7 KIR61671.1 - 0.052 13.6 0.5 0.15 12.2 0.2 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR61671.1 - 0.055 12.9 0.2 0.19 11.2 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KIR61671.1 - 0.072 13.1 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_40 PF14493.6 KIR61671.1 - 0.098 13.1 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 KIR61671.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HisKA_3 PF07730.13 KIR61672.1 - 1.8e-18 66.8 8.4 1.8e-18 66.8 8.4 3.9 5 0 0 5 5 5 1 Histidine kinase HATPase_c PF02518.26 KIR61672.1 - 4.8e-07 30.3 0.1 9.6e-06 26.1 0.0 2.7 2 2 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR61672.1 - 0.0022 17.9 0.1 0.0022 17.9 0.1 2.7 3 1 0 3 3 3 1 Histidine kinase-like ATPase domain PDDEXK_1 PF12705.7 KIR61673.1 - 8.6e-37 127.4 0.0 1e-36 127.2 0.0 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KIR61673.1 - 0.00011 22.3 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF83 DUF2800 PF10926.8 KIR61673.1 - 0.00037 19.9 0.0 0.003 16.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2800) Peptidase_M50 PF02163.22 KIR61674.1 - 1.5e-15 57.2 1.6 1.2e-06 28.0 0.3 2.6 1 1 1 2 2 2 2 Peptidase family M50 Peptidase_M50B PF13398.6 KIR61674.1 - 6.3e-06 26.0 1.7 6.3e-06 26.0 1.7 2.3 1 1 1 2 2 2 1 Peptidase M50B-like DUF3267 PF11667.8 KIR61674.1 - 0.0059 16.9 0.5 0.03 14.6 0.0 2.2 3 0 0 3 3 3 1 Putative zincin peptidase Fer4_15 PF13459.6 KIR61676.1 - 4.4e-20 72.2 0.2 5.7e-20 71.8 0.2 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KIR61676.1 - 5.7e-12 46.0 0.0 8.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 KIR61676.1 - 0.0001 22.3 0.1 0.00038 20.5 0.0 1.8 2 0 0 2 2 2 1 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 KIR61676.1 - 0.0015 18.3 2.2 0.0067 16.2 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 KIR61676.1 - 0.28 11.3 1.9 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain AAA PF00004.29 KIR61677.1 - 7.5e-49 165.5 0.0 2.6e-48 163.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 KIR61677.1 - 7.8e-26 89.5 1.7 1.3e-25 88.8 0.3 2.2 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain Prot_ATP_ID_OB PF16450.5 KIR61677.1 - 3.3e-15 55.8 0.3 7e-13 48.3 0.0 2.8 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KIR61677.1 - 1.3e-07 32.2 1.4 3.2e-05 24.4 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KIR61677.1 - 1e-05 25.9 0.0 2.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 KIR61677.1 - 3.6e-05 23.6 0.0 0.002 17.9 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIR61677.1 - 6.4e-05 23.1 0.0 0.00024 21.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) CENP-F_leu_zip PF10473.9 KIR61677.1 - 9e-05 22.5 1.2 0.00021 21.3 1.2 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 KIR61677.1 - 0.00013 22.2 0.9 0.00079 19.7 0.0 2.6 3 1 0 3 3 1 1 AAA domain Cep57_CLD_2 PF14197.6 KIR61677.1 - 0.00087 19.3 0.7 0.00087 19.3 0.7 2.3 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 AAA_5 PF07728.14 KIR61677.1 - 0.00087 19.3 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KIR61677.1 - 0.002 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIR61677.1 - 0.0028 17.8 0.1 0.0072 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain Jnk-SapK_ap_N PF09744.9 KIR61677.1 - 0.0029 17.9 4.3 0.0065 16.7 4.3 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Mg_chelatase PF01078.21 KIR61677.1 - 0.003 17.0 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KIR61677.1 - 0.0047 16.9 0.0 0.17 11.8 0.0 2.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea HAP1_N PF04849.13 KIR61677.1 - 0.0048 16.2 1.6 0.0083 15.4 1.6 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ADIP PF11559.8 KIR61677.1 - 0.0069 16.5 6.2 0.013 15.6 6.2 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding NACHT PF05729.12 KIR61677.1 - 0.0069 16.3 0.2 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 KIR61677.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KIR61677.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SOGA PF11365.8 KIR61677.1 - 0.013 16.6 5.4 0.092 13.9 5.4 2.2 1 1 0 1 1 1 0 Protein SOGA AAA_23 PF13476.6 KIR61677.1 - 0.019 15.5 2.7 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF812 PF05667.11 KIR61677.1 - 0.021 13.7 4.0 0.032 13.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_18 PF13238.6 KIR61677.1 - 0.024 15.2 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 KIR61677.1 - 0.026 14.5 5.3 0.046 13.7 4.4 1.9 2 0 0 2 2 1 0 Laminin Domain II IstB_IS21 PF01695.17 KIR61677.1 - 0.027 14.2 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0242 PF06785.11 KIR61677.1 - 0.027 14.6 3.8 0.044 13.9 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RILP PF11461.8 KIR61677.1 - 0.029 14.6 0.7 0.077 13.2 0.7 1.7 1 0 0 1 1 1 0 Rab interacting lysosomal protein CALCOCO1 PF07888.11 KIR61677.1 - 0.032 13.1 4.9 0.048 12.5 4.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med9 PF07544.13 KIR61677.1 - 0.035 14.2 2.7 0.14 12.3 1.3 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 KIR61677.1 - 0.036 14.3 9.8 0.056 13.7 9.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_14 PF13173.6 KIR61677.1 - 0.04 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Vir_act_alpha_C PF10400.9 KIR61677.1 - 0.042 14.5 2.3 0.13 13.0 2.3 1.9 1 0 0 1 1 1 0 Virulence activator alpha C-term FAM76 PF16046.5 KIR61677.1 - 0.044 13.1 1.3 0.067 12.5 1.3 1.1 1 0 0 1 1 1 0 FAM76 protein AAA_25 PF13481.6 KIR61677.1 - 0.045 13.3 0.5 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIR61677.1 - 0.046 12.9 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KIR61677.1 - 0.049 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIR61677.1 - 0.055 12.5 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 FapA PF03961.13 KIR61677.1 - 0.094 11.3 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_24 PF13479.6 KIR61677.1 - 0.11 12.2 0.1 0.43 10.3 0.1 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KIR61677.1 - 0.12 12.9 0.2 0.79 10.2 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Fib_alpha PF08702.10 KIR61677.1 - 0.13 12.4 0.5 0.29 11.3 0.5 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ZnuA PF01297.17 KIR61677.1 - 0.14 11.5 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic FUSC PF04632.12 KIR61677.1 - 0.15 10.6 5.7 0.19 10.2 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NB-ARC PF00931.22 KIR61677.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Lebercilin PF15619.6 KIR61677.1 - 0.16 11.6 6.2 0.31 10.7 6.2 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 KIR61677.1 - 0.18 12.3 3.1 0.22 12.0 0.7 2.3 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 KIR61677.1 - 0.2 12.2 9.7 0.34 11.4 9.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Myosin_tail_1 PF01576.19 KIR61677.1 - 0.2 9.4 5.4 0.28 9.0 5.4 1.1 1 0 0 1 1 1 0 Myosin tail DUF773 PF05600.12 KIR61677.1 - 0.22 10.2 1.1 0.33 9.6 1.1 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 CEP63 PF17045.5 KIR61677.1 - 0.23 11.3 6.5 0.36 10.7 6.5 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa BRE1 PF08647.11 KIR61677.1 - 0.24 11.5 4.7 0.42 10.7 4.7 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KIR61677.1 - 0.25 10.2 6.6 0.47 9.3 6.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 KIR61677.1 - 0.42 9.9 6.7 0.69 9.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 KIR61677.1 - 0.45 9.8 6.9 2.9 7.2 7.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding BCAS2 PF05700.11 KIR61677.1 - 0.54 9.9 5.8 0.59 9.8 4.4 1.7 2 0 0 2 2 1 0 Breast carcinoma amplified sequence 2 (BCAS2) KASH_CCD PF14662.6 KIR61677.1 - 0.84 9.4 6.3 4 7.2 6.3 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BST2 PF16716.5 KIR61677.1 - 0.9 10.2 7.7 0.65 10.6 5.2 2.0 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 ERM PF00769.19 KIR61677.1 - 0.94 9.2 7.1 1.6 8.5 7.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-H PF05837.12 KIR61677.1 - 1.6 9.2 7.4 4.2 7.8 7.4 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 KIR61677.1 - 1.7 8.4 5.9 41 4.0 5.9 2.6 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 KIR61677.1 - 1.8 7.6 5.1 2.8 7.0 5.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 KIR61677.1 - 2 8.7 8.1 2.5 8.4 6.0 2.3 2 1 0 2 2 1 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 KIR61677.1 - 2.4 8.5 4.9 5.8 7.3 4.9 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 KIR61677.1 - 2.6 8.7 9.6 2.8 8.6 4.0 3.1 2 1 1 3 3 2 0 SlyX Spc24 PF08286.11 KIR61677.1 - 2.9 8.2 4.9 31 4.9 0.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 KIR61677.1 - 3.4 7.9 5.5 48 4.2 5.5 2.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CLZ PF16526.5 KIR61677.1 - 5.1 7.5 6.6 29 5.1 2.1 2.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-Q PF13094.6 KIR61677.1 - 7.5 6.7 9.3 4.1 7.6 6.9 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Pup_ligase PF03136.15 KIR61678.1 - 2e-188 626.9 0.0 2.3e-188 626.7 0.0 1.0 1 0 0 1 1 1 1 Pup-ligase protein Pup PF05639.11 KIR61679.1 - 1.4e-29 102.8 5.8 1.5e-29 102.6 5.8 1.0 1 0 0 1 1 1 1 Pup-like protein Apolipoprotein PF01442.18 KIR61679.1 - 0.0055 16.6 0.3 0.0061 16.5 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2205 PF10224.9 KIR61679.1 - 0.011 15.8 0.9 0.013 15.4 0.9 1.1 1 0 0 1 1 1 0 Short coiled-coil protein TH1 PF04858.13 KIR61679.1 - 0.014 14.0 0.5 0.015 13.9 0.5 1.0 1 0 0 1 1 1 0 TH1 protein HSCB_C PF07743.13 KIR61679.1 - 0.016 15.7 1.3 0.019 15.4 1.3 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain PMC2NT PF08066.12 KIR61679.1 - 0.064 13.9 0.6 0.072 13.8 0.6 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF5132 PF17195.4 KIR61679.1 - 0.067 13.3 1.9 0.067 13.3 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF5132) Endonuclease_7 PF02945.15 KIR61680.1 - 2.5e-23 81.8 0.2 2.5e-23 81.8 0.2 3.1 3 1 0 3 3 3 1 Recombination endonuclease VII Stc1 PF12898.7 KIR61680.1 - 1.1e-05 25.9 9.4 0.0058 17.2 0.1 2.7 3 0 0 3 3 3 2 Stc1 domain Lar_restr_allev PF14354.6 KIR61680.1 - 0.00091 19.6 7.3 1.4 9.4 0.2 3.2 3 0 0 3 3 3 2 Restriction alleviation protein Lar SBP PF03110.14 KIR61680.1 - 0.47 10.8 7.7 17 5.8 1.8 2.9 1 1 1 2 2 2 0 SBP domain His_Me_b4a2 PF18275.1 KIR61680.1 - 1 9.5 5.2 0.31 11.2 0.3 2.4 2 1 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain UPF0547 PF10571.9 KIR61680.1 - 2.2 8.4 14.6 0.33 11.1 0.6 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DZR PF12773.7 KIR61680.1 - 9.1 6.4 17.2 1.4e+02 2.6 10.5 4.0 2 2 0 2 2 2 0 Double zinc ribbon Proteasome PF00227.26 KIR61681.1 - 2.7e-33 115.1 0.1 3.8e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KIR61682.1 - 1.7e-31 109.2 0.3 2e-31 109.0 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Pup_ligase PF03136.15 KIR61683.1 - 1.6e-159 531.7 0.1 3.1e-159 530.7 0.1 1.4 1 1 0 1 1 1 1 Pup-ligase protein DUF3866 PF12982.7 KIR61685.1 - 1.1e-123 412.5 0.0 1.2e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3866) Cation_efflux PF01545.21 KIR61686.1 - 3.2e-35 121.7 13.1 3.8e-35 121.4 13.1 1.0 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIR61686.1 - 0.0048 17.0 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF1700 PF08006.11 KIR61686.1 - 0.17 11.4 0.4 0.49 9.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PTR2 PF00854.21 KIR61686.1 - 0.33 9.7 3.3 0.33 9.7 0.8 2.0 1 1 1 2 2 2 0 POT family WYL PF13280.6 KIR61687.1 - 1.8e-31 109.5 0.0 2.8e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 WYL domain WYL PF13280.6 KIR61688.1 - 6.5e-33 114.2 0.6 1.3e-32 113.2 0.5 1.5 1 1 1 2 2 2 1 WYL domain MttA_Hcf106 PF02416.16 KIR61689.1 - 4.1e-17 61.3 0.0 5e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family Pex14_N PF04695.13 KIR61689.1 - 0.14 12.8 8.1 0.15 12.7 8.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.6 KIR61689.1 - 5.5 6.1 13.5 5.7 6.1 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TatC PF00902.18 KIR61690.1 - 9.9e-59 198.6 10.5 1.3e-58 198.3 10.5 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DAGK_cat PF00781.24 KIR61692.1 - 1.4e-23 82.8 0.0 4.1e-23 81.4 0.1 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KIR61692.1 - 2.4e-06 27.0 0.2 3.1e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Oxidored_q6 PF01058.22 KIR61692.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF2804 PF10974.8 KIR61693.1 - 3.4e-87 293.0 0.0 3.8e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) RibD_C PF01872.17 KIR61694.1 - 1.9e-23 83.3 0.0 2.3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Glyco_hydro_127 PF07944.12 KIR61695.1 - 7.3e-139 463.6 0.1 9.4e-139 463.2 0.1 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 RicinB_lectin_2 PF14200.6 KIR61695.1 - 2.5e-25 89.0 16.0 3.2e-14 53.4 4.8 3.6 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR61695.1 - 1.5e-06 28.5 0.4 1.1e-05 25.6 0.4 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain DUF4986 PF16375.5 KIR61695.1 - 0.032 14.9 0.0 0.087 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function SpoIIE PF07228.12 KIR61695.1 - 0.1 12.5 0.0 16 5.4 0.0 2.5 1 1 1 2 2 2 0 Stage II sporulation protein E (SpoIIE) Peripla_BP_3 PF13377.6 KIR61696.1 - 1.2e-33 116.8 2.8 1.3e-33 116.6 0.2 2.2 2 1 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR61696.1 - 2.8e-20 71.8 1.3 4e-20 71.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 KIR61696.1 - 1e-14 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR61696.1 - 2.4e-14 53.5 0.0 4.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_23 PF13384.6 KIR61696.1 - 0.00089 19.0 0.2 0.37 10.7 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 KIR61696.1 - 0.0012 18.9 0.0 0.0048 16.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 KIR61696.1 - 0.0017 18.7 1.1 0.016 15.5 1.1 2.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KIR61696.1 - 0.004 16.9 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR61696.1 - 0.0052 16.2 0.1 0.014 14.8 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 rRNA_methylase PF06962.12 KIR61696.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase MarR_2 PF12802.7 KIR61696.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.0 4 0 0 4 4 4 0 MarR family HTH_28 PF13518.6 KIR61696.1 - 0.38 10.9 2.9 3.3 7.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Peptidase_M48 PF01435.18 KIR61697.1 - 2.4e-06 27.5 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Phage-tail_3 PF13550.6 KIR61698.1 - 0.062 13.2 1.8 0.11 12.3 1.5 1.6 1 1 0 1 1 1 0 Putative phage tail protein Acetyltransf_1 PF00583.25 KIR61699.1 - 1.5e-11 44.5 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR61699.1 - 6.1e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR61699.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MarR_2 PF12802.7 KIR61699.1 - 5.2e-08 32.7 3.2 5.7e-08 32.5 1.0 2.4 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KIR61699.1 - 9.5e-06 26.0 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 KIR61699.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 KIR61699.1 - 0.00021 21.4 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 KIR61699.1 - 0.001 19.0 0.2 0.0036 17.3 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain FR47 PF08445.10 KIR61699.1 - 0.0016 18.4 0.0 0.0058 16.6 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_13 PF13880.6 KIR61699.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KIR61699.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 KIR61699.1 - 0.04 13.6 0.3 0.094 12.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ DprA_WH PF17782.1 KIR61699.1 - 0.051 13.7 3.5 0.074 13.2 2.0 2.1 2 0 0 2 2 2 0 DprA winged helix domain DciA PF05258.12 KIR61700.1 - 0.076 13.4 0.3 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA IclR PF01614.18 KIR61701.1 - 3.4e-22 78.7 0.0 4.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR61701.1 - 6e-12 45.2 2.0 1e-11 44.5 0.5 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 KIR61701.1 - 0.00036 20.5 1.1 0.001 19.1 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR61701.1 - 0.0018 18.1 0.5 0.0018 18.1 0.5 2.3 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 KIR61701.1 - 0.091 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain MOSC PF03473.17 KIR61702.1 - 1.6e-18 67.0 0.0 2.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 KIR61702.1 - 0.16 11.9 0.5 0.37 10.7 0.5 1.6 1 0 0 1 1 1 0 3-alpha domain Fer4_15 PF13459.6 KIR61703.1 - 7.6e-15 55.4 1.0 8.6e-15 55.2 1.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KIR61703.1 - 2.4e-09 37.6 0.1 2.7e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 KIR61703.1 - 0.0001 22.3 0.0 0.00015 21.7 0.0 1.3 1 1 0 1 1 1 1 Divergent 4Fe-4S mono-cluster IU_nuc_hydro PF01156.19 KIR61704.1 - 6e-65 219.8 0.1 7.2e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase BPD_transp_1 PF00528.22 KIR61705.1 - 1.1e-08 35.1 19.9 1.1e-08 35.1 19.9 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4244 PF14029.6 KIR61705.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4244) PfkB PF00294.24 KIR61706.1 - 5e-56 190.2 2.9 5.6e-56 190.0 2.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIR61706.1 - 5.9e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CHAT PF12770.7 KIR61706.1 - 0.049 13.0 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 CHAT domain ToxS PF17323.2 KIR61707.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS Amidohydro_1 PF01979.20 KIR61708.1 - 2e-22 80.0 0.1 2.5e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family DHOase PF12890.7 KIR61708.1 - 0.00051 20.0 0.0 0.0022 17.9 0.0 1.9 1 1 0 1 1 1 1 Dihydro-orotase-like BPD_transp_2 PF02653.16 KIR61709.1 - 2.3e-44 151.6 55.8 2.3e-44 151.6 55.8 1.9 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 KIR61710.1 - 6.4e-49 166.0 0.0 1.6e-28 99.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR61710.1 - 9.3e-09 35.5 0.3 0.016 15.0 0.0 3.4 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 KIR61710.1 - 0.00036 19.4 1.0 0.41 9.4 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class SMC_N PF02463.19 KIR61710.1 - 0.00043 19.8 0.1 0.61 9.5 0.0 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR61710.1 - 0.00048 19.8 0.0 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KIR61710.1 - 0.00055 19.7 1.2 0.64 9.7 0.0 3.4 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.6 KIR61710.1 - 0.00058 20.1 0.9 0.22 11.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KIR61710.1 - 0.0011 19.6 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR61710.1 - 0.0016 18.9 1.7 0.62 10.4 0.5 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KIR61710.1 - 0.0044 16.8 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR61710.1 - 0.01 15.7 0.2 0.055 13.4 0.0 2.2 3 1 0 3 3 3 0 RsgA GTPase SbcCD_C PF13558.6 KIR61710.1 - 0.044 14.0 0.3 13 6.1 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CobA_CobO_BtuR PF02572.15 KIR61710.1 - 0.052 13.8 0.2 0.36 11.1 0.1 2.2 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RepB PF07506.11 KIR61710.1 - 0.055 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein ATP-synt_ab PF00006.25 KIR61710.1 - 0.068 12.8 0.0 4.9 6.7 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KIR61710.1 - 0.069 12.7 0.6 4.5 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KIR61710.1 - 0.074 13.6 1.9 14 6.2 0.4 3.8 3 1 1 4 4 4 0 AAA domain AAA_27 PF13514.6 KIR61710.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIR61710.1 - 0.12 12.4 0.5 27 4.8 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 KIR61710.1 - 0.13 11.3 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain Peripla_BP_4 PF13407.6 KIR61711.1 - 8.3e-63 212.4 9.1 1.1e-62 211.9 9.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KIR61711.1 - 1e-06 28.4 0.3 4.3e-06 26.4 0.2 2.1 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family UPF0180 PF03698.13 KIR61711.1 - 0.11 12.7 0.1 0.75 10.0 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) Beta-lactamase2 PF13354.6 KIR61712.1 - 8.5e-35 120.2 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KIR61712.1 - 9.8e-05 21.7 1.1 9.8e-05 21.7 1.1 1.8 2 1 0 2 2 2 1 Beta-lactamase Peptidase_S11 PF00768.20 KIR61712.1 - 0.00076 19.0 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase TPR_4 PF07721.14 KIR61712.1 - 6 7.8 10.0 14 6.6 6.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RibD_C PF01872.17 KIR61714.1 - 1.5e-23 83.7 0.0 1.8e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain FGGY_N PF00370.21 KIR61715.1 - 1.4e-35 123.0 0.0 8e-35 120.6 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIR61715.1 - 2.9e-27 95.7 0.0 5.3e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BSP PF04450.12 KIR61715.1 - 0.087 12.6 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase of plants and bacteria Aminotran_3 PF00202.21 KIR61716.1 - 1.5e-49 168.8 0.0 3.5e-49 167.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Aldolase_II PF00596.21 KIR61716.1 - 1.9e-44 151.9 0.1 4.6e-44 150.6 0.0 1.7 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain HTH_30 PF13556.6 KIR61717.1 - 3e-18 65.4 1.8 3e-18 65.4 1.8 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 KIR61717.1 - 4.4e-05 23.3 0.0 0.00015 21.7 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 KIR61717.1 - 0.014 15.5 0.2 0.014 15.5 0.2 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR61717.1 - 0.04 13.5 0.3 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR61717.1 - 0.13 12.1 0.2 0.13 12.1 0.2 4.0 2 2 1 3 3 3 0 MarR family Sigma70_r4_2 PF08281.12 KIR61717.1 - 0.16 11.7 1.0 5.6 6.7 0.1 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 TetR_C_33 PF13305.6 KIR61718.1 - 5.7e-21 75.2 3.2 5.7e-21 75.2 3.2 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR61718.1 - 1.4e-07 31.2 1.4 2.3e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_28 PF13518.6 KIR61718.1 - 0.00086 19.4 1.1 0.11 12.6 0.0 3.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 KIR61718.1 - 0.077 12.8 0.0 0.24 11.2 0.0 1.8 1 1 0 1 1 1 0 HTH DNA binding domain HTH_22 PF13309.6 KIR61718.1 - 0.091 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_7 PF02796.15 KIR61718.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase FBP_C PF16571.5 KIR61719.1 - 8.1e-59 197.6 0.0 9.1e-59 197.4 0.0 1.0 1 0 0 1 1 1 1 FBP C-terminal treble-clef zinc-finger DUF4383 PF14325.6 KIR61720.1 - 0.018 15.3 0.7 0.026 14.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) PGPGW PF09656.10 KIR61720.1 - 0.54 9.8 5.1 3.7 7.1 2.7 2.4 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) CRCB PF02537.15 KIR61721.1 - 2.8e-26 91.7 6.5 3.2e-26 91.4 6.5 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) SNF PF00209.18 KIR61721.1 - 0.056 12.1 0.1 0.073 11.7 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family ADH_zinc_N_2 PF13602.6 KIR61722.1 - 4.3e-21 76.4 0.4 4.3e-21 76.4 0.4 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR61722.1 - 2.7e-16 59.8 2.4 2.7e-16 59.8 2.4 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR61722.1 - 1.5e-05 24.8 0.0 5.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIR61722.1 - 0.0048 16.4 3.6 0.01 15.3 3.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 KIR61722.1 - 0.083 13.2 1.8 0.088 13.1 0.4 1.6 2 0 0 2 2 2 0 TrkA-N domain ADH_N_2 PF16884.5 KIR61722.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AAA_16 PF13191.6 KIR61723.1 - 1.7e-25 90.4 4.1 1.7e-25 90.4 4.1 4.4 4 2 2 6 6 4 1 AAA ATPase domain GerE PF00196.19 KIR61723.1 - 3e-19 68.3 0.1 5.6e-19 67.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR61723.1 - 4.4e-06 26.3 1.8 7.8e-05 22.3 0.0 3.5 4 0 0 4 4 4 1 Sigma-70, region 4 AAA_22 PF13401.6 KIR61723.1 - 4.5e-06 27.0 0.1 2.6e-05 24.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain Sigma70_r4 PF04545.16 KIR61723.1 - 1.2e-05 24.7 0.4 0.00055 19.4 0.1 3.1 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_12 PF13424.6 KIR61723.1 - 0.00016 21.9 51.7 0.0017 18.6 3.3 7.5 7 1 1 8 8 6 3 Tetratricopeptide repeat HTH_23 PF13384.6 KIR61723.1 - 0.0029 17.4 0.1 0.028 14.2 0.1 2.8 1 0 0 1 1 1 1 Homeodomain-like domain Zeta_toxin PF06414.12 KIR61723.1 - 0.067 12.5 0.3 0.29 10.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KIR61723.1 - 0.068 13.1 0.0 0.53 10.1 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_2 PF07719.17 KIR61723.1 - 0.089 13.0 33.3 4.8 7.5 4.1 8.2 7 1 1 8 8 8 0 Tetratricopeptide repeat NACHT PF05729.12 KIR61723.1 - 0.21 11.5 2.7 3.5 7.5 2.7 2.5 1 1 0 1 1 1 0 NACHT domain ParD_antitoxin PF03693.14 KIR61723.1 - 0.23 11.9 1.3 2.2 8.8 0.1 2.9 2 1 1 3 3 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TPR_7 PF13176.6 KIR61723.1 - 0.66 10.1 7.3 65 3.9 1.1 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF627 PF04781.12 KIR61723.1 - 1.2 9.2 6.4 0.52 10.4 3.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ANAPC5 PF12862.7 KIR61723.1 - 6.6 6.9 7.8 37 4.5 1.3 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KIR61723.1 - 9.2 6.7 9.4 12 6.3 2.1 4.1 2 1 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 KIR61725.1 - 7.7e-13 48.9 9.7 6.6e-09 36.0 1.5 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIR61725.1 - 0.009 15.6 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Chlam_PMP PF02415.17 KIR61726.1 - 3.7 8.2 47.0 0.3 11.6 0.3 8.4 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat HHH_5 PF14520.6 KIR61728.1 - 4.8e-06 27.1 0.0 8.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 KIR61728.1 - 0.00044 20.5 0.0 0.00072 19.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) Cdd1 PF11731.8 KIR61728.1 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KIR61728.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Nitro_FeMo-Co PF02579.17 KIR61728.1 - 0.039 14.3 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor TfoX_C PF04994.13 KIR61728.1 - 0.25 11.4 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 TfoX C-terminal domain FAD_binding_3 PF01494.19 KIR61729.1 - 8.5e-18 64.7 4.9 5.5e-08 32.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KIR61729.1 - 0.0012 19.0 1.3 0.0046 17.2 1.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR61729.1 - 0.0019 17.5 0.6 0.0076 15.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR61729.1 - 0.11 13.1 0.8 0.25 11.9 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR61729.1 - 0.15 11.2 4.9 0.038 13.1 1.4 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KIR61729.1 - 0.17 11.5 6.4 0.12 12.0 3.7 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 KIR61729.1 - 0.2 10.7 0.0 1.8 7.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Cyclase_polyket PF04673.12 KIR61730.1 - 2.2e-37 127.5 0.0 2.5e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Polyketide synthesis cyclase BTAD PF03704.17 KIR61731.1 - 9.9e-17 61.7 9.3 9.9e-17 61.7 9.3 1.5 1 1 0 1 1 1 1 Bacterial transcriptional activator domain Cyclase_polyket PF04673.12 KIR61732.1 - 5e-43 145.6 0.0 5.6e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Polyketide synthesis cyclase Polyketide_cyc2 PF10604.9 KIR61733.1 - 2.4e-14 53.8 2.9 3.3e-14 53.4 2.9 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR61733.1 - 7.7e-13 48.8 1.2 1.2e-12 48.1 1.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PP-binding PF00550.25 KIR61733.1 - 4.1e-07 30.2 0.3 8.1e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Cupin_2 PF07883.11 KIR61734.1 - 4.1e-20 71.3 0.3 5.9e-20 70.8 0.3 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIR61734.1 - 3.2e-07 30.3 0.0 4.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KIR61734.1 - 3.1e-06 27.2 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 KIR61734.1 - 4.4e-05 23.2 0.0 5.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Cupin_6 PF12852.7 KIR61734.1 - 0.00019 21.2 0.3 0.00028 20.6 0.3 1.4 1 1 0 1 1 1 1 Cupin Cupin_1 PF00190.22 KIR61734.1 - 0.0078 15.8 0.1 0.021 14.4 0.1 1.6 1 1 0 1 1 1 1 Cupin CENP-C_C PF11699.8 KIR61734.1 - 0.015 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Pirin_C PF05726.13 KIR61734.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Auxin_BP PF02041.16 KIR61734.1 - 0.18 11.4 0.0 0.5 10.0 0.0 1.6 1 1 0 1 1 1 0 Auxin binding protein ABM PF03992.16 KIR61735.1 - 1e-13 51.2 0.2 1.4e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AMP-binding PF00501.28 KIR61736.1 - 9.8e-30 103.5 1.9 5.3e-29 101.1 1.9 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR61736.1 - 6.1e-12 46.4 0.3 3.7e-11 43.8 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACPS PF01648.20 KIR61737.1 - 1.2e-13 51.2 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KIR61737.1 - 0.066 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain PP-binding PF00550.25 KIR61738.1 - 0.00025 21.3 0.6 0.00032 21.0 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 KIR61740.1 - 5.2e-29 100.7 0.0 1.2e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KIR61740.1 - 5e-15 55.8 15.8 2.8e-12 46.8 13.0 3.4 2 1 1 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KIR61740.1 - 3.4 7.0 5.9 3.1 7.1 0.9 2.5 3 0 0 3 3 3 0 Thiolase, N-terminal domain AMP-binding PF00501.28 KIR61741.1 - 7.2e-55 186.3 0.0 1e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR61741.1 - 0.072 14.1 2.1 0.17 12.8 2.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 KIR61742.1 - 3.5e-45 154.6 2.7 5.8e-45 153.8 2.7 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIR61742.1 - 5.8e-37 126.3 0.5 1.5e-36 125.0 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KIR61742.1 - 4.9e-06 26.1 2.2 4.9e-06 26.1 2.2 2.2 2 1 0 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KIR61742.1 - 0.053 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KIR61742.1 - 0.16 11.9 2.3 3.7 7.5 0.3 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyoxalase PF00903.25 KIR61743.1 - 1.3e-24 86.8 0.1 2.5e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIR61743.1 - 6.7e-19 68.2 0.2 2.2e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KIR61743.1 - 1.1e-07 32.1 0.0 4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KIR61743.1 - 3.2e-07 30.6 5.6 0.0054 16.9 0.3 3.2 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KIR61743.1 - 0.54 11.1 7.2 0.83 10.5 0.4 2.8 3 0 0 3 3 3 0 Glyoxalase-like domain PhyH PF05721.13 KIR61744.1 - 2e-23 83.8 0.2 2.6e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3050 PF11251.8 KIR61745.1 - 8.8e-96 320.0 0.0 1e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Haem_oxygenas_2 PF14518.6 KIR61745.1 - 3.1e-11 43.4 0.1 4e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme T2SSF PF00482.23 KIR61745.1 - 0.0067 16.4 0.0 0.024 14.6 0.0 1.9 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein F E1_dh PF00676.20 KIR61746.1 - 2.7e-61 207.2 0.0 3.5e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 KIR61746.1 - 0.00082 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 KIR61746.1 - 0.0033 16.7 0.1 0.005 16.1 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KIR61746.1 - 0.029 14.2 1.9 1.1 9.1 1.9 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Chal_sti_synt_N PF00195.19 KIR61746.1 - 0.15 11.4 0.7 0.25 10.7 0.7 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain Transket_pyr PF02779.24 KIR61747.1 - 1.3e-31 109.6 0.0 2.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIR61747.1 - 2.4e-29 101.7 0.0 3.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KIR61747.1 - 0.00029 21.1 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II GSP_synth PF03738.14 KIR61748.1 - 6.8e-06 25.5 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 2 Glutathionylspermidine synthase preATP-grasp ATPgrasp_YheCD PF14398.6 KIR61748.1 - 0.00017 21.0 0.0 0.00034 20.0 0.0 1.5 1 1 0 1 1 1 1 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 KIR61748.1 - 0.011 15.2 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain PhoR PF11808.8 KIR61748.1 - 0.026 14.9 0.3 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR CP_ATPgrasp_2 PF14403.6 KIR61748.1 - 0.04 12.8 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 ATP-grasp_3 PF02655.14 KIR61748.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain AMP-binding PF00501.28 KIR61750.1 - 3.8e-58 197.1 0.0 6.2e-58 196.4 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR61750.1 - 9.3e-19 68.2 0.8 2e-18 67.1 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 KIR61751.1 - 1.9e-33 115.9 0.0 4.2e-30 104.9 0.0 3.0 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 KIR61752.1 - 1.5e-77 260.2 0.3 2e-77 259.8 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIR61752.1 - 3.1e-11 42.8 0.3 8.3e-11 41.4 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIR61752.1 - 5.7e-08 32.5 0.0 0.0022 17.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KIR61752.1 - 3e-05 23.7 0.0 0.0026 17.3 0.0 2.3 1 1 1 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KIR61752.1 - 0.12 11.6 0.0 9.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIR61752.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Aminotran_1_2 PF00155.21 KIR61753.1 - 2.8e-27 95.8 0.0 3.6e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIR61753.1 - 5e-05 22.3 0.1 0.00012 21.0 0.1 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KIR61753.1 - 0.22 10.8 0.5 0.84 8.9 0.1 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4177 PF13783.6 KIR61754.1 - 0.00014 22.0 0.1 0.00018 21.7 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4177) SHMT PF00464.19 KIR61755.1 - 4.1e-122 407.6 0.0 2.5e-93 312.9 0.0 2.2 2 0 0 2 2 2 2 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KIR61755.1 - 7.7e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Metallophos PF00149.28 KIR61756.1 - 1.1e-17 65.3 0.0 1.6e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR61756.1 - 9.8e-06 25.9 0.0 0.0056 16.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Hemerythrin PF01814.23 KIR61757.1 - 6.1e-14 52.8 9.1 6.1e-14 52.8 9.1 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain SpecificRecomb PF10136.9 KIR61757.1 - 0.028 12.7 0.7 0.032 12.5 0.7 1.1 1 0 0 1 1 1 0 Site-specific recombinase MeaB PF03308.16 KIR61757.1 - 0.071 12.1 0.2 5.6 5.8 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Peptidase_S8 PF00082.22 KIR61758.1 - 1.9e-44 152.1 8.3 3e-44 151.5 8.3 1.2 1 0 0 1 1 1 1 Subtilase family DUF4350 PF14258.6 KIR61758.1 - 0.14 12.6 0.8 0.39 11.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) DUF4179 PF13786.6 KIR61758.1 - 2.2 8.8 5.0 97 3.5 5.0 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Carb_kinase PF01256.17 KIR61759.1 - 1.8e-39 135.7 0.5 2.1e-39 135.4 0.5 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KIR61759.1 - 0.028 13.8 0.1 0.19 11.1 0.1 2.0 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Acyl_transf_3 PF01757.22 KIR61760.1 - 4.8e-25 88.3 17.5 6.5e-25 87.9 17.5 1.1 1 0 0 1 1 1 1 Acyltransferase family DNA_primase_S PF01896.19 KIR61761.1 - 0.037 14.1 0.0 0.89 9.6 0.0 2.1 1 1 0 1 1 1 0 DNA primase small subunit HTH_24 PF13412.6 KIR61762.1 - 1.2e-14 53.5 0.6 2e-14 52.8 0.6 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KIR61762.1 - 1.4e-14 53.6 4.4 2.8e-14 52.6 4.4 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KIR61762.1 - 2.8e-10 40.0 0.4 4.9e-10 39.2 0.1 1.6 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 KIR61762.1 - 2.5e-05 24.0 1.6 4e-05 23.4 0.3 1.9 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 KIR61762.1 - 3e-05 24.0 0.4 6.1e-05 23.0 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KIR61762.1 - 0.00031 20.6 0.1 0.00051 19.9 0.1 1.3 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 KIR61762.1 - 0.00057 19.7 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 KIR61762.1 - 0.00081 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KIR61762.1 - 0.0083 16.5 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator GYD PF08734.11 KIR61762.1 - 0.032 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 GYD domain HTH_IclR PF09339.10 KIR61762.1 - 0.049 13.4 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain RuvB_C PF05491.13 KIR61762.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain HTH_50 PF18024.1 KIR61762.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KIR61762.1 - 0.12 12.5 0.1 0.5 10.5 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KIR61762.1 - 0.17 12.1 2.0 0.21 11.7 0.7 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Transket_pyr PF02779.24 KIR61763.1 - 1.3e-45 155.2 0.0 2.1e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIR61763.1 - 2e-38 131.1 0.1 7.4e-38 129.2 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KIR61763.1 - 0.0036 17.6 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 KIR61764.1 - 9.7e-72 241.2 0.0 1.2e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIR61764.1 - 4.7e-17 61.6 0.2 8e-17 60.9 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIR61764.1 - 1.3e-13 51.0 1.1 3e-13 49.9 1.1 1.7 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.19 KIR61764.1 - 0.022 14.6 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein Beta_helix PF13229.6 KIR61765.1 - 1.8e-19 70.1 8.5 1e-06 28.7 0.9 4.1 3 1 1 4 4 4 4 Right handed beta helix region Pectate_lyase_3 PF12708.7 KIR61765.1 - 1.2e-08 35.0 4.2 1.6e-07 31.4 1.2 2.9 1 1 1 2 2 2 1 Pectate lyase superfamily protein NosD PF05048.13 KIR61765.1 - 1.6e-07 30.8 0.0 0.00046 19.5 0.0 3.0 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) End_N_terminal PF12218.8 KIR61765.1 - 0.14 11.9 0.2 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Big_10 PF17964.1 KIR61766.1 - 4.5e-42 144.1 0.6 8e-42 143.3 0.6 1.4 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 KIR61766.1 - 9.3e-16 58.5 0.9 3e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 KIR61766.1 - 0.017 15.8 3.2 0.1 13.3 1.3 2.9 2 2 1 3 3 3 0 Bacterial Ig-like domain TcfC PF16967.5 KIR61766.1 - 0.18 11.3 0.0 31 4.1 0.0 2.7 3 0 0 3 3 3 0 E-set like domain Str_synth PF03088.16 KIR61767.1 - 2.1e-20 72.6 0.0 7.8e-20 70.8 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 KIR61767.1 - 1e-15 58.0 0.0 3.3e-14 53.1 0.0 2.1 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KIR61767.1 - 2.7e-05 24.0 1.0 1.2 9.4 0.0 4.3 4 0 0 4 4 4 3 NHL repeat BAT PF15915.5 KIR61767.1 - 0.2 11.5 0.6 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 GAF and HTH_10 associated domain CBS PF00571.28 KIR61768.1 - 4e-27 94.4 9.2 2.1e-13 50.5 0.1 2.7 3 0 0 3 3 3 2 CBS domain BON PF04972.17 KIR61768.1 - 1.2e-09 38.3 6.6 1.2e-09 38.3 6.6 1.9 2 0 0 2 2 2 1 BON domain DUF2726 PF10881.8 KIR61769.1 - 3.3e-07 30.2 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2726) Lsr2 PF11774.8 KIR61771.1 - 8e-39 132.2 0.1 9e-39 132.0 0.1 1.0 1 0 0 1 1 1 1 Lsr2 Lon_C PF05362.13 KIR61772.1 - 1.7e-85 285.7 0.0 2.7e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KIR61772.1 - 1.4e-19 70.8 0.0 2.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KIR61772.1 - 5.2e-19 69.0 0.0 8.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KIR61772.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KIR61772.1 - 3.8e-07 30.2 0.0 8.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIR61772.1 - 0.00016 21.8 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIR61772.1 - 0.0012 19.1 0.8 0.025 14.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIR61772.1 - 0.0013 19.2 0.3 0.0013 19.2 0.3 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 KIR61772.1 - 0.0047 17.1 0.4 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIR61772.1 - 0.009 16.6 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIR61772.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KIR61772.1 - 0.019 14.9 0.1 0.15 12.0 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_3 PF07726.11 KIR61772.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIR61772.1 - 0.023 14.4 0.0 0.071 12.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MEDS PF14417.6 KIR61772.1 - 0.032 14.1 4.2 0.5 10.2 0.2 2.6 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_25 PF13481.6 KIR61772.1 - 0.048 13.2 2.8 0.11 12.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KIR61772.1 - 0.076 12.3 1.1 0.44 9.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 KIR61772.1 - 0.18 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DoxX_2 PF13564.6 KIR61773.1 - 8.5e-25 86.9 16.1 1e-24 86.6 16.1 1.0 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 KIR61773.1 - 0.00067 20.2 11.7 0.00067 20.2 11.7 2.6 2 1 0 2 2 2 1 DoxX YrhC PF14143.6 KIR61773.1 - 0.028 14.5 2.0 0.065 13.3 0.4 2.1 2 1 0 2 2 2 0 YrhC-like protein MauE PF07291.11 KIR61773.1 - 0.34 10.7 13.8 0.042 13.6 9.0 1.9 1 1 0 1 1 1 0 Methylamine utilisation protein MauE DUF4131 PF13567.6 KIR61773.1 - 3.8 7.1 6.5 47 3.6 6.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) SLATT_1 PF18181.1 KIR61773.1 - 8.5 6.3 7.3 2.9 7.8 4.2 1.8 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DEAD PF00270.29 KIR61774.1 - 4.1e-50 170.0 0.0 1.5e-49 168.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR61774.1 - 2.4e-29 101.9 0.0 8.3e-29 100.2 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DbpA PF03880.15 KIR61774.1 - 1.7e-24 85.6 0.2 3.6e-24 84.5 0.2 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 KIR61774.1 - 0.0008 19.5 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit WSD PF15613.6 KIR61774.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif 2_5_RNA_ligase2 PF13563.6 KIR61775.1 - 3.6e-12 46.4 0.1 4.2e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIR61775.1 - 0.013 15.7 0.1 0.044 14.0 0.0 1.8 2 0 0 2 2 2 0 LigT like Phosphoesterase Glyco_hydro_9 PF00759.19 KIR61776.1 - 4.6e-99 332.6 14.4 6.2e-99 332.2 14.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 KIR61776.1 - 3.2e-27 94.8 14.5 3.2e-27 94.8 14.5 2.8 3 0 0 3 3 3 1 Cellulose binding domain CelD_N PF02927.14 KIR61776.1 - 7.6e-23 81.2 0.2 1.9e-22 79.9 0.2 1.7 1 0 0 1 1 1 1 Cellulase N-terminal ig-like domain Asn_synthase PF00733.21 KIR61778.1 - 9e-61 206.5 4.1 8.5e-31 107.9 0.1 2.2 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KIR61778.1 - 2.5e-39 134.0 0.0 3.9e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIR61778.1 - 9.6e-32 110.0 0.0 2.1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KIR61778.1 - 0.0019 17.7 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 KIR61778.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIR61778.1 - 0.039 12.7 0.0 0.076 11.8 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase LPD22 PF18834.1 KIR61778.1 - 0.15 12.3 0.2 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 NAD_synthase PF02540.17 KIR61778.1 - 0.25 10.4 0.0 0.42 9.7 0.0 1.3 1 0 0 1 1 1 0 NAD synthase CBM_25 PF03423.13 KIR61780.1 - 9.9e-62 205.8 34.4 2.2e-35 121.1 7.4 3.4 3 0 0 3 3 3 2 Carbohydrate binding domain (family 25) Alpha-amylase PF00128.24 KIR61780.1 - 1.8e-40 139.5 6.9 9e-23 81.4 0.2 3.2 2 1 0 3 3 3 3 Alpha amylase, catalytic domain CBM53 PF16760.5 KIR61780.1 - 4.7e-18 65.5 1.8 1.1e-08 35.5 0.3 2.9 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) CBM26 PF16738.5 KIR61780.1 - 2.3e-06 27.7 5.1 3.7e-05 23.9 1.0 2.8 2 0 0 2 2 2 1 Starch-binding module 26 fn3 PF00041.21 KIR61780.1 - 0.00088 19.6 0.2 0.0026 18.1 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF1093 PF06486.11 KIR61780.1 - 0.85 10.3 2.9 0.43 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1093) CBM_21 PF03370.13 KIR61780.1 - 1.1 9.5 5.3 8.2 6.6 0.4 2.4 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) CBAH PF02275.18 KIR61781.1 - 1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family AAT PF03417.16 KIR61781.1 - 1.3e-08 34.8 0.0 9.8e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase LPAM_1 PF08139.12 KIR61781.1 - 0.091 13.3 3.4 0.43 11.2 3.4 2.3 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Radical_SAM PF04055.21 KIR61782.1 - 0.00018 21.9 0.1 0.0019 18.6 0.1 2.6 1 1 0 2 2 2 1 Radical SAM superfamily Glycos_transf_2 PF00535.26 KIR61783.1 - 0.00091 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 PSD3 PF07626.11 KIR61783.1 - 0.14 12.6 1.3 1.7 9.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1587) NTP_transferase PF00483.23 KIR61784.1 - 2.5e-14 53.5 0.0 3.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR61784.1 - 1.5e-05 25.4 2.5 4.8e-05 23.8 2.5 1.9 1 1 0 1 1 1 1 MobA-like NTP transferase domain HisKA_3 PF07730.13 KIR61786.1 - 1.6e-21 76.6 3.8 1.6e-21 76.6 3.8 2.1 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 KIR61786.1 - 1.3e-05 25.6 0.0 4.7e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR61786.1 - 2.5e-05 24.2 0.0 2.5e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain DUF4225 PF13988.6 KIR61786.1 - 2.2 7.8 3.8 1 8.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4225) Response_reg PF00072.24 KIR61787.1 - 7.3e-27 93.8 0.1 1.1e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR61787.1 - 6.2e-20 70.5 0.4 9.8e-20 69.9 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR61787.1 - 7.7e-13 47.9 0.8 1.6e-12 46.9 0.3 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR61787.1 - 8e-06 25.3 1.2 8e-06 25.3 1.2 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 KIR61787.1 - 1.8e-05 24.4 0.1 3.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR61787.1 - 0.00021 21.0 1.3 0.00043 20.0 0.3 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KIR61787.1 - 0.00066 19.2 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 KIR61787.1 - 0.0069 16.8 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF742 PF05331.11 KIR61787.1 - 0.017 14.9 0.3 0.041 13.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_29 PF13551.6 KIR61787.1 - 0.022 14.8 0.1 0.066 13.2 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_ECF PF07638.11 KIR61787.1 - 0.026 14.4 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 ECF sigma factor HTH_AsnC-type PF13404.6 KIR61787.1 - 0.035 13.9 0.1 0.087 12.7 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 KIR61787.1 - 0.049 13.7 0.6 0.15 12.1 0.6 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KIR61787.1 - 0.059 13.5 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain UDPG_MGDP_dh_N PF03721.14 KIR61788.1 - 1.4e-36 125.9 0.0 2.5e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KIR61788.1 - 1.1e-26 92.8 0.0 2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KIR61788.1 - 1.4e-21 76.9 0.0 5.7e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KIR61788.1 - 0.00012 22.3 0.0 0.00035 20.8 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KIR61788.1 - 0.00025 20.5 0.2 0.23 10.8 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIR61788.1 - 0.0016 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KIR61788.1 - 0.0065 16.7 0.6 0.71 10.1 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain 3HCDH_N PF02737.18 KIR61788.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KIR61788.1 - 0.029 14.9 0.9 10 6.7 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain Pyr_redox PF00070.27 KIR61788.1 - 0.043 14.4 0.1 1.4 9.5 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR61788.1 - 0.13 11.4 0.3 0.27 10.4 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIR61789.1 - 1.1e-43 149.5 0.0 1.4e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR61789.1 - 5.9e-28 97.9 0.0 7.4e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR61789.1 - 5.8e-10 39.5 1.0 5.2e-05 23.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR61789.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIR61789.1 - 0.00021 20.9 0.0 0.00032 20.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIR61789.1 - 0.00063 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIR61789.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIR61789.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIR61789.1 - 0.047 12.7 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KIR61789.1 - 0.28 10.8 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Sigma70_r2 PF04542.14 KIR61790.1 - 5.6e-14 51.7 0.7 5.6e-14 51.7 0.7 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR61790.1 - 2.7e-09 36.6 0.4 2.7e-09 36.6 0.4 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR61790.1 - 0.00015 21.2 0.4 0.00015 21.2 0.4 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR61790.1 - 0.17 11.8 1.1 0.74 9.7 1.1 2.0 1 1 0 1 1 1 0 ECF sigma factor GCS2 PF04107.13 KIR61791.1 - 2.4e-50 171.6 0.4 4e-50 170.8 0.4 1.4 1 1 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) FGE-sulfatase PF03781.16 KIR61792.1 - 2.9e-64 217.2 7.7 3.7e-64 216.8 7.7 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIR61792.1 - 2.3e-27 96.0 1.6 2.3e-27 96.0 1.6 2.3 2 0 0 2 2 2 1 DinB superfamily DUF664 PF04978.12 KIR61792.1 - 0.0079 16.6 0.2 0.0079 16.6 0.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF664) GATase_6 PF13522.6 KIR61793.1 - 5.7e-17 62.2 0.4 1.1e-16 61.2 0.4 1.4 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIR61793.1 - 3e-10 39.4 0.0 3.4e-08 32.7 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Methyltransf_33 PF10017.9 KIR61794.1 - 2.8e-115 384.7 0.0 3.2e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 KIR61794.1 - 0.0057 17.3 0.0 0.018 15.7 0.0 1.8 2 1 1 3 3 3 1 Methyltransferase domain UPF0016 PF01169.19 KIR61795.1 - 2.9e-43 146.1 22.0 1.5e-21 76.5 5.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Abhydrolase_9_N PF15420.6 KIR61795.1 - 0.0018 18.3 6.0 0.0018 18.3 6.0 2.1 1 1 1 2 2 2 1 Alpha/beta-hydrolase family N-terminus TauE PF01925.19 KIR61795.1 - 0.018 14.7 17.6 0.46 10.1 5.8 2.3 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF4131 PF13567.6 KIR61795.1 - 0.05 13.2 7.5 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 KIR61795.1 - 0.35 10.5 0.0 0.35 10.5 0.0 2.0 3 0 0 3 3 3 0 Tetraspanin family Acyl_transf_3 PF01757.22 KIR61795.1 - 1.2 8.2 11.1 1.4 7.9 9.3 1.8 1 1 0 1 1 1 0 Acyltransferase family DUF1622 PF07784.11 KIR61796.1 - 0.04 13.8 1.5 0.053 13.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) CbiA PF01656.23 KIR61798.1 - 1.5e-14 54.1 0.0 7.4e-12 45.4 0.0 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KIR61798.1 - 4.3e-12 46.0 0.2 1.4e-08 34.5 0.1 3.0 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Wzz PF02706.15 KIR61798.1 - 1.1e-09 38.4 0.1 2.1e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Chain length determinant protein AAA_31 PF13614.6 KIR61798.1 - 2e-08 34.4 0.0 4.1e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KIR61798.1 - 9.3e-06 25.1 0.1 3.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ GNVR PF13807.6 KIR61798.1 - 6.8e-05 22.7 0.7 0.00075 19.4 0.0 2.5 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase SRP54 PF00448.22 KIR61798.1 - 0.0024 17.5 0.5 0.0071 16.0 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KIR61798.1 - 0.01 15.4 1.2 0.041 13.4 0.9 2.2 1 1 1 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KIR61798.1 - 0.017 14.3 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase VirC1 PF07015.11 KIR61798.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein CLP1_P PF16575.5 KIR61798.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 KIR61798.1 - 0.046 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase FTHFS PF01268.19 KIR61798.1 - 0.063 11.5 0.0 0.093 10.9 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase LMWPc PF01451.21 KIR61799.1 - 3.9e-19 69.4 0.0 5.9e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyco_trans_4_4 PF13579.6 KIR61800.1 - 2.4e-17 63.9 17.4 2.4e-17 63.9 17.4 2.8 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KIR61800.1 - 1.7e-13 51.1 0.2 6.7e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR61800.1 - 5.1e-13 49.4 2.1 1.2e-12 48.2 2.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIR61800.1 - 1.2e-11 44.4 0.0 2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR61800.1 - 0.095 12.7 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KIR61800.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 Starch synthase catalytic domain CarboxypepD_reg PF13620.6 KIR61801.1 - 0.0006 20.0 4.7 0.0015 18.8 4.7 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KIR61801.1 - 0.0092 16.0 1.5 0.0092 16.0 1.5 2.1 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) DUF4198 PF10670.9 KIR61801.1 - 0.03 14.7 0.1 0.041 14.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) ACC_epsilon PF13822.6 KIR61801.1 - 1.4 9.7 8.1 0.13 13.0 1.4 2.6 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit 5_nucleotid_C PF02872.18 KIR61803.1 - 2.1e-28 99.5 0.0 4.9e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIR61803.1 - 1.9e-11 44.9 0.0 3.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PsbQ PF05757.11 KIR61803.1 - 0.1 12.4 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) AbiEii PF08843.11 KIR61804.1 - 4.7e-13 49.7 2.0 9.1e-13 48.7 2.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF1383 PF07134.11 KIR61804.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) ABC_tran PF00005.27 KIR61807.1 - 1.8e-19 70.6 0.0 2e-10 41.3 0.0 3.8 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 KIR61807.1 - 1.5e-08 34.3 0.0 0.027 13.9 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR61807.1 - 1.1e-06 28.3 0.4 0.031 14.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR61807.1 - 1.8e-06 28.4 0.4 0.05 14.0 0.0 3.1 4 0 0 4 4 4 2 AAA ATPase domain DnaJ_CXXCXGXG PF00684.19 KIR61807.1 - 3.2e-05 24.2 2.8 0.0092 16.3 0.3 3.2 3 0 0 3 3 3 1 DnaJ central domain RsgA_GTPase PF03193.16 KIR61807.1 - 0.00031 20.7 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KIR61807.1 - 0.00095 19.3 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIR61807.1 - 0.0012 18.6 0.1 0.061 13.1 0.1 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 KIR61807.1 - 0.0018 18.1 8.9 2 8.1 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIR61807.1 - 0.0092 15.7 0.0 39 3.8 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain cobW PF02492.19 KIR61807.1 - 0.016 14.8 0.7 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIR61807.1 - 0.019 14.9 0.2 7.4 6.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain UvrA_DNA-bind PF17755.1 KIR61807.1 - 0.026 14.9 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 UvrA DNA-binding domain AAA_25 PF13481.6 KIR61807.1 - 0.04 13.5 1.3 19 4.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KIR61807.1 - 0.049 14.1 0.0 7.5 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIR61807.1 - 0.068 13.7 1.4 24 5.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 KIR61807.1 - 0.075 12.7 2.4 4.4 7.0 0.3 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KIR61807.1 - 0.21 11.9 3.3 28 5.0 0.3 3.3 3 0 0 3 3 3 0 AAA domain Anti-TRAP PF15777.5 KIR61807.1 - 0.65 10.0 6.4 2.4 8.2 0.1 3.1 3 1 1 4 4 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Peptidase_S11 PF00768.20 KIR61808.1 - 7.3e-38 130.4 0.0 9.9e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KIR61808.1 - 3.6e-09 36.5 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 KIR61808.1 - 0.038 12.7 0.1 0.1 11.3 0.0 1.6 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Glyco_trans_1_4 PF13692.6 KIR61809.1 - 4.6e-08 33.6 0.9 9.1e-08 32.6 0.4 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 MGDG_synth PF06925.11 KIR61809.1 - 2.3e-07 31.1 0.0 4.1e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 KIR61809.1 - 1.9e-05 24.7 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 KIR61809.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 KIR61809.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Shikimate_DH PF01488.20 KIR61809.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EamA PF00892.20 KIR61810.1 - 0.004 17.3 16.9 0.58 10.3 0.2 4.4 3 1 0 4 4 4 3 EamA-like transporter family Romo1 PF10247.9 KIR61810.1 - 1.4 9.3 7.4 1.5 9.2 1.5 3.4 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 DUF4389 PF14333.6 KIR61810.1 - 5.2 7.1 6.8 0.95 9.4 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF1056 PF06341.11 KIR61810.1 - 8 6.9 6.5 2 8.8 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) Pro_isomerase PF00160.21 KIR61811.1 - 2.1e-25 89.8 0.0 3e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Esterase PF00756.20 KIR61812.1 - 3.4e-27 95.7 0.0 5.3e-27 95.1 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KIR61812.1 - 6e-05 22.4 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIR61812.1 - 0.0043 16.9 0.1 0.0097 15.8 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KIR61812.1 - 0.013 15.0 1.2 0.24 10.9 0.9 2.4 1 1 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR61812.1 - 0.015 14.8 0.2 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIR61812.1 - 0.02 14.7 0.0 0.47 10.2 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KIR61812.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold RtcB PF01139.17 KIR61814.1 - 7.4e-126 420.7 0.0 1.4e-125 419.7 0.0 1.4 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB SmpB PF01668.18 KIR61815.1 - 7.5e-57 191.2 0.0 8.7e-57 191.0 0.0 1.0 1 0 0 1 1 1 1 SmpB protein PTS_2-RNA PF01885.16 KIR61816.1 - 7.8e-38 130.3 0.0 8.9e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PhdYeFM_antitox PF02604.19 KIR61817.1 - 0.017 14.9 0.6 0.042 13.6 0.6 1.9 1 1 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Hydrolase PF00702.26 KIR61817.1 - 0.078 13.2 1.9 0.094 13.0 1.9 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase V-ATPase_G_2 PF16999.5 KIR61817.1 - 1.1 9.6 10.0 4.6 7.7 10.0 1.9 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Acetyltransf_3 PF13302.7 KIR61818.1 - 5.1e-18 66.1 0.0 6.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR61818.1 - 8.6e-07 29.2 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR61818.1 - 0.0054 16.4 0.1 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KIR61819.1 - 3.3e-80 269.8 0.0 8.8e-80 268.4 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR61819.1 - 2e-54 185.0 0.0 1.2e-43 149.5 0.0 4.1 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 KIR61819.1 - 1.2e-24 86.4 0.2 1.1e-11 45.0 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR61819.1 - 1.3e-14 54.9 3.0 1.4e-06 29.2 1.5 3.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_21 PF05050.12 KIR61819.1 - 2.6e-11 43.9 0.0 5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_24 PF13578.6 KIR61819.1 - 0.025 15.6 0.9 0.51 11.4 0.1 3.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KIR61819.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Thioesterase PF00975.20 KIR61820.1 - 1.5e-37 129.9 0.0 1.7e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KIR61820.1 - 7.5e-09 36.5 12.5 8.9e-09 36.3 12.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIR61820.1 - 0.0024 17.7 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR61820.1 - 0.0028 17.0 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KIR61820.1 - 0.035 13.6 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KIR61820.1 - 0.051 13.3 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KIR61820.1 - 0.077 12.8 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KIR61820.1 - 0.098 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LCAT PF02450.15 KIR61820.1 - 0.33 10.1 0.0 0.41 9.7 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cys_Met_Meta_PP PF01053.20 KIR61821.1 - 2.1e-122 408.4 0.0 2.4e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIR61821.1 - 5.5e-11 42.2 0.0 7.6e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIR61821.1 - 3.7e-09 36.0 0.4 5.1e-09 35.6 0.4 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 KIR61821.1 - 9.7e-06 24.8 0.3 0.00024 20.2 0.3 2.1 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Met_gamma_lyase PF06838.11 KIR61821.1 - 1.8e-05 23.5 0.0 2.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KIR61821.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_1 PF00561.20 KIR61822.1 - 1.8e-29 103.2 0.1 1.1e-28 100.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR61822.1 - 1.7e-10 40.6 0.2 1.2e-09 37.8 0.1 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIR61822.1 - 2.9e-05 22.9 0.0 4.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 KIR61822.1 - 0.0029 16.5 0.0 0.0044 15.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 KIR61822.1 - 0.0085 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.18 KIR61822.1 - 0.054 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_8 PF06259.12 KIR61822.1 - 0.11 12.1 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase HCV_core PF01542.18 KIR61823.1 - 0.26 11.7 1.6 9.3 6.7 0.0 2.7 2 1 1 3 3 3 0 Hepatitis C virus core protein HTH_31 PF13560.6 KIR61824.1 - 2.3e-14 53.5 0.9 2.3e-14 53.5 0.9 4.2 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61824.1 - 1.4e-12 47.5 0.0 8.4e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR61824.1 - 3.2e-12 46.3 0.0 1.7e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR61824.1 - 0.0018 17.8 0.0 0.0048 16.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 KIR61824.1 - 0.005 16.8 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR61824.1 - 0.0071 16.8 0.1 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KIR61824.1 - 0.0074 15.8 0.1 0.28 10.8 0.0 3.2 4 0 0 4 4 4 1 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 KIR61824.1 - 0.13 12.1 0.0 0.54 10.2 0.0 2.0 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_31 PF13560.6 KIR61825.1 - 1.6e-09 38.0 3.5 1.6e-09 38.0 3.5 4.9 4 2 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61825.1 - 5.2e-05 23.2 0.1 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR61825.1 - 0.0052 16.8 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HSP90 PF00183.18 KIR61826.1 - 2.9e-135 452.1 0.0 3.8e-129 431.9 0.0 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 KIR61826.1 - 7.6e-13 48.5 0.1 1.8e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIR61826.1 - 2.9e-11 43.9 0.0 5.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acetyltransf_3 PF13302.7 KIR61827.1 - 1.5e-11 45.2 0.0 1.8e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR61827.1 - 2.4e-09 37.5 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4956 PF16316.5 KIR61828.1 - 3.3e-58 196.2 1.9 3.7e-58 196.0 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4956) SurE PF01975.17 KIR61828.1 - 0.039 13.7 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Survival protein SurE Wzy_C PF04932.15 KIR61828.1 - 2.6 7.7 6.8 47 3.6 6.7 2.1 1 1 0 1 1 1 0 O-Antigen ligase DUF4395 PF14340.6 KIR61829.1 - 1.6e-39 135.2 14.0 1.8e-39 135.1 14.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) TMEM141 PF15110.6 KIR61829.1 - 0.24 12.0 1.1 19 5.9 0.0 2.2 2 0 0 2 2 2 0 TMEM141 protein family DUF4231 PF14015.6 KIR61829.1 - 5.7 7.5 5.6 5.9 7.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Flavin_Reduct PF01613.18 KIR61830.1 - 2.8e-37 128.1 0.3 3.3e-37 127.9 0.3 1.0 1 0 0 1 1 1 1 Flavin reductase like domain SBP_bac_6 PF13343.6 KIR61831.1 - 2.4e-32 112.3 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61831.1 - 5.7e-20 72.3 0.2 7.7e-20 71.8 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR61831.1 - 1.3e-19 70.9 3.2 1.7e-19 70.5 3.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR61831.1 - 4.8e-13 49.7 2.4 6.8e-13 49.2 2.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ABC_tran PF00005.27 KIR61832.1 - 2.3e-30 105.9 0.0 3.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 KIR61832.1 - 6.4e-08 32.7 1.1 6.4e-08 32.7 1.1 3.1 3 2 0 3 3 3 1 TOBE domain AAA_21 PF13304.6 KIR61832.1 - 3.1e-07 30.5 0.0 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR61832.1 - 0.00014 22.3 1.9 0.00052 20.4 1.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIR61832.1 - 0.00058 19.3 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR61832.1 - 0.0039 17.5 0.1 0.018 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KIR61832.1 - 0.016 15.4 0.2 0.22 11.7 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KIR61832.1 - 0.043 14.2 0.1 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIR61832.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KIR61832.1 - 0.053 13.1 2.0 0.14 11.7 2.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR61832.1 - 0.065 12.9 4.0 0.042 13.6 1.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIR61832.1 - 0.078 13.5 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIR61832.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KIR61832.1 - 0.14 12.3 0.7 0.56 10.4 0.7 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR61832.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TOBE PF03459.17 KIR61832.1 - 0.17 12.2 4.8 0.1 12.9 1.0 2.6 3 0 0 3 3 3 0 TOBE domain ABC_ATPase PF09818.9 KIR61832.1 - 0.2 10.4 0.3 13 4.4 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class ATPase_2 PF01637.18 KIR61832.1 - 0.3 11.0 0.0 0.5 10.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP-grasp_4 PF13535.6 KIR61834.1 - 2.2e-17 63.1 0.0 3.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KIR61834.1 - 7.2e-16 58.1 0.5 7.2e-16 58.1 0.5 3.7 4 0 0 4 4 4 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_N PF18130.1 KIR61834.1 - 3.5e-09 37.1 1.4 2.5e-08 34.4 0.1 2.9 3 0 0 3 3 3 1 ATP-grasp N-terminal domain ATPgrasp_Ter PF15632.6 KIR61834.1 - 1.3e-07 31.5 0.1 1.1e-06 28.4 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KIR61834.1 - 1.4e-07 31.7 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KIR61834.1 - 3.2e-06 27.1 0.0 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KIR61834.1 - 1.1e-05 25.0 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF364 PF04016.12 KIR61835.1 - 5.8e-10 38.9 0.0 9.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Putative heavy-metal chelation PALP PF00291.25 KIR61836.1 - 1.8e-48 165.5 1.1 2e-48 165.3 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MR_MLE_C PF13378.6 KIR61837.1 - 8e-40 136.7 7.4 1.3e-39 136.0 7.4 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR61837.1 - 1.2e-06 28.7 0.2 4e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KIR61837.1 - 0.14 11.3 0.3 0.22 10.6 0.3 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus SBP_bac_5 PF00496.22 KIR61838.1 - 2e-63 214.7 0.0 2.4e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Trans_reg_C PF00486.28 KIR61839.1 - 3.4e-26 91.1 0.1 7e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KIR61839.1 - 1.3e-25 89.8 0.2 1.8e-25 89.3 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain TadZ_N PF16968.5 KIR61839.1 - 0.12 12.1 0.3 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Pilus assembly protein TadZ N-terminal Germane PF10646.9 KIR61840.1 - 1.2e-09 38.9 0.0 2.2e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Sporulation and spore germination RIP PF00161.19 KIR61841.1 - 8.9e-16 58.0 1.0 1.1e-15 57.8 1.0 1.1 1 0 0 1 1 1 1 Ribosome inactivating protein Glyco_hyd_65N_2 PF14498.6 KIR61842.1 - 2.8e-26 92.8 0.0 4.6e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SBP_bac_1 PF01547.25 KIR61843.1 - 9e-22 78.4 7.7 9e-22 78.4 7.7 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR61843.1 - 2.8e-17 63.4 1.4 6.2e-17 62.3 0.7 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein TAT_signal PF10518.9 KIR61843.1 - 1.1 9.2 6.4 6.4 6.8 6.4 2.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence BPD_transp_1 PF00528.22 KIR61844.1 - 1.2e-15 57.8 11.1 1.2e-15 57.8 11.1 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Colicin_V PF02674.16 KIR61844.1 - 0.31 11.0 14.3 0.21 11.5 3.6 3.2 3 0 0 3 3 3 0 Colicin V production protein BPD_transp_1 PF00528.22 KIR61845.1 - 8e-11 42.0 13.5 8e-11 42.0 13.5 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component NdhL PF10716.9 KIR61845.1 - 1.3 9.0 5.3 1.9 8.5 0.5 3.1 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit DUF2993 PF11209.8 KIR61846.1 - 9.9e-28 97.8 13.3 1.2e-27 97.6 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Trans_reg_C PF00486.28 KIR61847.1 - 3e-27 94.5 0.0 1.8e-25 88.8 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KIR61847.1 - 3.3e-25 88.4 0.0 4.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 KIR61847.1 - 0.019 15.4 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Glyco_transf_4 PF13439.6 KIR61847.1 - 0.047 13.7 0.3 1.6 8.7 0.1 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 B12-binding PF02310.19 KIR61847.1 - 0.053 13.6 0.1 0.61 10.1 0.1 2.1 1 1 1 2 2 2 0 B12 binding domain Aminotran_5 PF00266.19 KIR61848.1 - 6.9e-22 77.9 0.0 8.4e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR61848.1 - 0.017 13.7 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 KIR61848.1 - 0.24 10.0 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Radical_SAM PF04055.21 KIR61849.1 - 4.5e-17 62.9 0.0 6.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 KIR61849.1 - 4.6e-07 29.8 0.1 8.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 HemN C-terminal domain LRR_6 PF13516.6 KIR61850.1 - 0.0012 18.8 4.9 0.81 9.9 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 KIR61850.1 - 0.0026 18.1 0.1 1.2 9.6 0.1 4.1 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 KIR61851.1 - 0.017 15.6 0.0 2.2 8.8 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIR61851.1 - 0.072 13.2 2.9 0.18 11.9 0.1 2.6 2 0 0 2 2 2 0 Leucine Rich repeat SLATT_1 PF18181.1 KIR61852.1 - 0.11 12.5 0.9 0.18 11.8 0.9 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4179 PF13786.6 KIR61852.1 - 0.31 11.5 1.3 0.45 11.0 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DivIVA PF05103.13 KIR61853.1 - 0.00064 19.8 14.2 0.00064 19.8 14.2 5.6 1 1 3 4 4 4 1 DivIVA protein Cep57_CLD_2 PF14197.6 KIR61853.1 - 0.0072 16.4 1.8 0.0072 16.4 1.8 6.0 2 1 4 6 6 6 2 Centrosome localisation domain of PPC89 BRE1 PF08647.11 KIR61853.1 - 0.012 15.7 4.8 0.012 15.7 4.8 6.1 2 1 4 6 6 6 0 BRE1 E3 ubiquitin ligase DUF2968 PF11180.8 KIR61853.1 - 0.013 15.1 3.5 0.013 15.1 3.5 5.4 2 1 4 6 6 6 0 Protein of unknown function (DUF2968) Spc7 PF08317.11 KIR61853.1 - 0.21 10.4 66.7 0.54 9.1 4.2 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Ntox50 PF15542.6 KIR61853.1 - 0.77 10.6 2.5 1.4 9.7 0.1 2.6 3 2 0 3 3 3 0 Bacterial toxin 50 Apolipoprotein PF01442.18 KIR61853.1 - 0.92 9.4 102.1 0.67 9.8 48.8 3.7 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain FlaC_arch PF05377.11 KIR61853.1 - 3.2 8.2 11.6 2.3 8.7 0.5 5.3 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) YlqD PF11068.8 KIR61853.1 - 8.6 6.7 71.3 0.63 10.4 7.8 5.3 1 1 4 5 5 5 0 YlqD protein PYC_OADA PF02436.18 KIR61854.1 - 0.08 12.7 0.2 0.8 9.4 0.0 2.4 3 0 0 3 3 3 0 Conserved carboxylase domain PhyH PF05721.13 KIR61855.1 - 1.4e-06 28.7 0.1 2.5e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SpoU_methylase PF00588.19 KIR61856.1 - 6.8e-34 117.1 0.0 9.1e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SBF PF01758.16 KIR61857.1 - 1.4e-31 109.7 13.4 2.8e-31 108.7 13.4 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 KIR61857.1 - 1.2e-14 54.3 21.4 1.6e-14 54.0 21.4 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 KIR61857.1 - 1.1e-05 24.1 6.9 1.1e-05 24.1 6.9 2.0 3 0 0 3 3 3 1 Membrane transport protein DUF1304 PF06993.12 KIR61857.1 - 0.005 16.8 0.1 0.005 16.8 0.1 3.3 2 1 3 5 5 5 1 Protein of unknown function (DUF1304) AbrB PF05145.12 KIR61857.1 - 0.0068 15.4 3.5 0.0068 15.4 3.5 3.2 1 1 1 3 3 3 2 Transition state regulatory protein AbrB Glyco_hydro_12 PF01670.16 KIR61858.1 - 3.2e-32 112.3 14.4 3.2e-32 112.3 14.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 CBM_2 PF00553.19 KIR61858.1 - 7.5e-30 103.2 14.0 7.5e-30 103.2 14.0 3.6 3 1 1 4 4 4 1 Cellulose binding domain Inositol_P PF00459.25 KIR61859.1 - 1.6e-50 172.1 0.1 1.9e-50 171.9 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Acyl-CoA_dh_2 PF08028.11 KIR61860.1 - 2.3e-27 95.9 1.5 4.3e-27 95.0 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR61860.1 - 8.4e-08 32.9 0.1 8.4e-08 32.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIR61860.1 - 1.6e-05 25.1 0.7 2.8e-05 24.4 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR61860.1 - 0.005 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MLTR_LBD PF17765.1 KIR61861.1 - 1.1e-46 159.0 6.3 1.1e-46 159.0 6.3 1.8 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KIR61861.1 - 1.1e-16 60.9 11.7 1.2e-16 60.8 9.5 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR61861.1 - 6.2e-09 35.8 0.0 9.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 KIR61861.1 - 6.7e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 KIR61861.1 - 0.0039 17.2 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR61861.1 - 0.0089 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR61861.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 KIR61862.1 - 7.6e-15 55.3 0.2 1.1e-14 54.7 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR61862.1 - 6.4e-13 49.8 10.6 7.4e-13 49.6 10.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR61862.1 - 1.4e-06 27.8 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 YCII PF03795.14 KIR61863.1 - 1.1e-21 77.1 0.0 1.3e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Sigma70_r2 PF04542.14 KIR61864.1 - 2.4e-14 52.9 0.9 7.8e-14 51.2 0.9 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR61864.1 - 1.4e-06 27.8 0.4 5.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_2 PF07719.17 KIR61864.1 - 0.12 12.6 2.4 1.6 9.0 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 KIR61864.1 - 0.78 9.4 3.8 4.9 6.8 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KIR61864.1 - 4.3 8.4 37.2 2.9 9.0 2.7 6.1 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIR61864.1 - 9.8 6.5 7.7 2.5 8.4 0.9 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaB_bind PF10410.9 KIR61864.1 - 9.9 6.4 9.9 0.41 10.9 1.7 2.9 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase adh_short_C2 PF13561.6 KIR61865.1 - 8.4e-33 113.9 4.1 2.2e-31 109.2 4.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61865.1 - 4.8e-27 94.7 0.0 6.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61865.1 - 0.0024 17.8 1.6 0.012 15.5 1.7 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KIR61865.1 - 0.0036 16.8 0.1 0.0047 16.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 KIR61865.1 - 0.014 14.8 3.7 0.048 13.1 0.3 2.4 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 KIR61866.1 - 6.4e-53 179.9 54.4 5.9e-52 176.7 49.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Engrail_1_C_sig PF10525.9 KIR61866.1 - 0.058 12.6 0.1 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain DUF2270 PF10028.9 KIR61866.1 - 0.15 11.6 1.1 0.37 10.3 1.1 1.6 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) MFS_3 PF05977.13 KIR61866.1 - 0.23 9.8 41.5 0.0073 14.7 17.9 2.4 1 1 1 2 2 2 0 Transmembrane secretion effector GMC_oxred_N PF00732.19 KIR61867.1 - 1.1e-75 254.8 0.0 1.3e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIR61867.1 - 4.9e-40 137.4 0.1 8.3e-40 136.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIR61867.1 - 2.7e-07 30.1 0.5 0.0066 15.6 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 KIR61867.1 - 9.5e-07 28.7 3.3 6.3e-06 26.0 3.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR61867.1 - 2.7e-05 24.3 0.0 7.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR61867.1 - 7.5e-05 22.1 0.0 0.07 12.3 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIR61867.1 - 0.00063 18.9 0.4 0.0012 18.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIR61867.1 - 0.00072 18.9 0.0 1.3 8.3 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TetR_C_33 PF13305.6 KIR61868.1 - 1e-18 67.9 0.7 1e-18 67.9 0.7 2.3 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR61868.1 - 1.8e-12 46.9 1.3 3.2e-12 46.0 1.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 KIR61868.1 - 0.092 12.8 0.4 10 6.2 0.3 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RPE65 PF03055.15 KIR61869.1 - 5.2e-101 339.1 0.0 5.9e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein adh_short PF00106.25 KIR61871.1 - 3.5e-38 131.0 0.0 5.4e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR61871.1 - 7.5e-31 107.5 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR61871.1 - 8.4e-10 38.8 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIR61871.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIR61871.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIR61871.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.10 KIR61871.1 - 0.015 14.7 0.0 0.068 12.5 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 KIR61871.1 - 0.048 13.9 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain CMD PF02627.20 KIR61872.1 - 6.6e-09 35.7 0.0 3.7e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family CMD PF02627.20 KIR61873.1 - 8.5e-06 25.7 5.3 0.00024 21.1 0.3 3.1 3 0 0 3 3 3 2 Carboxymuconolactone decarboxylase family HTH_18 PF12833.7 KIR61874.1 - 2.7e-22 78.8 0.4 4.2e-22 78.2 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR61874.1 - 2e-19 69.2 0.3 1.7e-08 34.3 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1702 PF08012.11 KIR61875.1 - 1.3e-125 418.5 1.1 1.5e-125 418.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1702) 4HBT_2 PF13279.6 KIR61876.1 - 4.1e-08 33.7 0.0 4.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KIR61876.1 - 0.0033 17.7 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily NQR2_RnfD_RnfE PF03116.15 KIR61877.1 - 0.00022 20.8 22.2 0.0041 16.6 22.2 2.1 1 1 0 1 1 1 1 NQR2, RnfD, RnfE family Pyr_redox_3 PF13738.6 KIR61879.1 - 6.4e-47 160.3 0.0 7.9e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR61879.1 - 6.8e-14 51.8 0.0 1.3e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR61879.1 - 2.5e-05 24.7 0.0 3.2 8.4 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR61879.1 - 0.00017 20.4 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KIR61879.1 - 0.00022 20.9 0.1 0.36 10.4 0.0 3.2 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR61879.1 - 0.00048 20.3 0.0 0.0026 17.9 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIR61879.1 - 0.00059 19.2 0.0 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 KIR61879.1 - 0.012 14.1 0.0 1 7.7 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 KIR61879.1 - 0.026 13.6 0.0 0.086 11.9 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KIR61879.1 - 0.078 12.2 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 KIR61879.1 - 0.11 13.0 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Nitroreductase PF00881.24 KIR61880.1 - 6.5e-29 101.2 0.0 8.1e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIR61880.1 - 7.2e-09 35.5 0.1 0.0013 18.4 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase GCS2 PF04107.13 KIR61881.1 - 4.2e-48 164.2 2.6 5.9e-48 163.7 2.6 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) CMD PF02627.20 KIR61882.1 - 2.2e-11 43.6 5.8 2.3e-06 27.6 0.5 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MDMPI_N PF11716.8 KIR61884.1 - 2.1e-09 38.2 11.5 2.1e-09 38.2 11.5 1.8 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 KIR61884.1 - 0.00058 20.4 3.2 0.0025 18.3 3.2 1.9 1 1 0 1 1 1 1 DinB superfamily SCP2 PF02036.17 KIR61884.1 - 0.0029 18.1 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family SRA1 PF07304.11 KIR61884.1 - 0.063 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Acyl-CoA_dh_2 PF08028.11 KIR61885.1 - 3.2e-22 79.2 1.5 3.2e-22 79.2 1.5 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR61885.1 - 8.4e-08 32.9 0.2 2e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIR61885.1 - 0.0017 18.6 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glu_synthase PF01645.17 KIR61886.1 - 3.1e-74 250.3 0.0 4e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase SBP_bac_11 PF13531.6 KIR61887.1 - 9.6e-45 153.1 13.9 1.2e-44 152.8 13.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR61887.1 - 1.8e-18 67.6 0.6 2.3e-17 63.9 0.6 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 KIR61887.1 - 3e-05 23.9 4.8 8.1e-05 22.4 1.6 2.1 1 1 0 2 2 2 1 PBP superfamily domain SBP_bac_8 PF13416.6 KIR61887.1 - 4.4e-05 23.4 0.1 0.0073 16.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein PBP_like PF12727.7 KIR61887.1 - 7.3e-05 22.0 0.2 0.0011 18.1 0.2 2.3 1 1 0 1 1 1 1 PBP superfamily domain LysR_substrate PF03466.20 KIR61887.1 - 0.00015 21.2 2.8 0.00026 20.4 2.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain OpuAC PF04069.12 KIR61887.1 - 0.0014 18.3 0.2 0.0018 17.9 0.2 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_6 PF13343.6 KIR61887.1 - 0.0081 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein HDPD PF02924.14 KIR61887.1 - 9.1 6.4 16.7 17 5.5 16.7 1.5 1 1 0 1 1 1 0 Bacteriophage lambda head decoration protein D BPD_transp_1 PF00528.22 KIR61888.1 - 1.7e-21 76.8 15.7 1.7e-21 76.8 15.7 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PG_binding_1 PF01471.18 KIR61889.1 - 1.7e-22 79.4 0.0 2.9e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Amidase_2 PF01510.25 KIR61889.1 - 8.4e-17 61.8 0.1 2.6e-16 60.2 0.1 1.8 2 0 0 2 2 2 1 N-acetylmuramoyl-L-alanine amidase TAT_signal PF10518.9 KIR61889.1 - 0.037 13.9 1.2 0.091 12.6 1.2 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PG_binding_3 PF09374.10 KIR61889.1 - 0.056 13.7 0.6 15 5.9 0.0 3.1 3 1 1 4 4 4 0 Predicted Peptidoglycan domain PG_binding_2 PF08823.11 KIR61889.1 - 0.2 12.0 0.0 5 7.5 0.0 2.3 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Pkinase PF00069.25 KIR61890.1 - 6.1e-42 143.8 0.0 8.1e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR61890.1 - 7.2e-28 97.6 0.0 9.3e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR61890.1 - 1.3e-07 31.8 0.8 0.012 15.6 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR61890.1 - 0.0041 15.9 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase SOG2 PF10428.9 KIR61890.1 - 5.9 6.0 9.9 7.7 5.6 9.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TM_helix PF05552.12 KIR61891.1 - 1.7e-14 53.5 15.9 9.3e-13 47.9 3.3 3.3 3 1 0 3 3 3 2 Conserved TM helix RP1-2 PF12042.8 KIR61891.1 - 0.65 9.8 9.7 2.7 7.9 7.8 2.1 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain UPF0225 PF17775.1 KIR61892.1 - 6e-26 91.2 0.0 8e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 KIR61892.1 - 0.021 14.7 11.6 0.031 14.2 11.6 1.2 1 0 0 1 1 1 0 SEC-C motif SnoaL_2 PF12680.7 KIR61892.1 - 0.13 13.0 1.0 0.17 12.5 1.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain Peptidase_C39_2 PF13529.6 KIR61893.1 - 1e-21 78.0 0.3 2e-21 77.0 0.3 1.5 2 0 0 2 2 2 1 Peptidase_C39 like family Phytochelatin PF05023.14 KIR61893.1 - 2.5e-05 23.6 0.2 0.0002 20.7 0.2 2.0 1 1 0 1 1 1 1 Phytochelatin synthase BtrH_N PF14399.6 KIR61893.1 - 0.0066 16.7 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal CorA PF01544.18 KIR61894.1 - 1.9e-54 185.0 0.1 2.2e-54 184.8 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sortase PF04203.13 KIR61895.1 - 1.6e-19 70.0 0.0 2.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Sortase domain Lycopene_cycl PF05834.12 KIR61897.1 - 5.4e-72 242.9 0.1 6.2e-72 242.7 0.1 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIR61897.1 - 0.18 11.8 0.8 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Beta-lactamase PF00144.24 KIR61898.1 - 2.2e-52 178.3 10.8 6.1e-52 176.9 10.8 1.6 1 1 0 1 1 1 1 Beta-lactamase RNase_H PF00075.24 KIR61899.1 - 9.5e-47 158.8 0.0 1.2e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KIR61899.1 - 0.0023 17.7 0.1 0.0075 16.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like RecC_C PF17946.1 KIR61899.1 - 0.038 13.8 0.5 0.045 13.5 0.5 1.1 1 0 0 1 1 1 0 RecC C-terminal domain p450 PF00067.22 KIR61900.1 - 2.6e-36 125.4 0.0 7.6e-32 110.6 0.0 3.1 1 1 0 1 1 1 1 Cytochrome P450 Pentapeptide PF00805.22 KIR61902.1 - 8.2e-20 70.1 4.1 5.6e-11 41.9 0.6 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KIR61902.1 - 0.00089 19.4 0.0 0.0083 16.3 0.0 2.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 KIR61902.1 - 0.0044 17.2 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) RtcB PF01139.17 KIR61903.1 - 1.6e-147 492.0 0.0 1.9e-147 491.8 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Archease PF01951.16 KIR61904.1 - 2.1e-19 70.1 0.0 2.6e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) FMO-like PF00743.19 KIR61905.1 - 1.2e-12 47.0 0.0 4.6e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KIR61905.1 - 7e-11 42.2 0.3 3.8e-07 30.2 0.0 3.0 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR61905.1 - 9.8e-11 41.4 0.0 4.2e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR61905.1 - 1.1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIR61905.1 - 1.7e-06 27.4 0.3 0.00025 20.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIR61905.1 - 3.1e-06 27.6 0.2 0.011 16.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIR61905.1 - 8.8e-06 25.1 0.0 0.00019 20.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIR61905.1 - 0.00046 19.9 13.1 0.00082 19.1 0.4 3.9 2 1 2 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIR61905.1 - 0.0017 17.7 4.8 0.75 9.0 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain Shikimate_DH PF01488.20 KIR61905.1 - 0.0039 17.3 0.1 0.27 11.3 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Mqo PF06039.15 KIR61905.1 - 0.014 14.0 0.1 3.6 6.0 0.0 2.4 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.6 KIR61905.1 - 0.04 14.4 0.4 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 KIR61905.1 - 0.073 12.4 0.3 0.073 12.4 0.3 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR61905.1 - 0.093 11.8 2.1 0.22 10.5 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KIR61905.1 - 0.095 12.7 7.6 2.5 8.1 0.1 3.9 4 1 0 4 4 4 0 FAD-NAD(P)-binding SnoaL_4 PF13577.6 KIR61905.1 - 0.095 12.8 3.2 0.12 12.5 1.0 2.2 1 1 1 2 2 2 0 SnoaL-like domain DUF3601 PF12208.8 KIR61905.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) SnoaL_2 PF12680.7 KIR61905.1 - 0.17 12.6 4.8 0.085 13.5 1.0 2.5 2 1 0 2 2 2 0 SnoaL-like domain GIDA PF01134.22 KIR61905.1 - 0.43 9.6 1.6 2.9 6.9 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Abhydrolase_6 PF12697.7 KIR61906.1 - 9.1e-22 78.7 23.7 1.1e-21 78.5 23.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR61906.1 - 9.1e-22 77.9 0.1 1e-19 71.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR61906.1 - 1.4e-14 54.0 0.8 2.6e-14 53.1 0.8 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIR61906.1 - 8.2e-10 39.2 0.1 1.6e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KIR61906.1 - 0.0066 16.2 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KIR61906.1 - 0.19 11.3 0.1 0.58 9.7 0.1 1.7 1 1 0 2 2 2 0 Putative esterase DPRP PF04244.13 KIR61907.1 - 2.9e-14 53.5 0.0 4.9e-13 49.4 0.0 2.3 1 1 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein ADH_N PF08240.12 KIR61908.1 - 1.9e-27 95.3 1.7 1.9e-27 95.3 1.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR61908.1 - 6.2e-27 94.1 0.0 1.1e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIR61908.1 - 1.8e-08 34.1 2.3 1.1e-06 28.3 0.8 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIR61908.1 - 3.7e-07 31.2 0.0 6.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIR61908.1 - 0.0064 16.7 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KIR61908.1 - 0.023 15.3 0.3 0.023 15.3 0.3 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KIR61908.1 - 0.067 12.5 0.8 0.12 11.7 0.8 1.4 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 KIR61908.1 - 1.8 7.8 12.0 0.33 10.2 6.5 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lactamase_B PF00753.27 KIR61909.1 - 1.5e-22 80.6 12.2 2e-22 80.2 12.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR61909.1 - 0.025 14.1 2.8 0.042 13.4 2.8 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ATXN-1_C PF12547.8 KIR61909.1 - 0.064 13.6 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Lactamase_B_3 PF13483.6 KIR61909.1 - 0.069 13.0 0.4 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain MEDS PF14417.6 KIR61910.1 - 1.4e-37 129.0 0.3 1.6e-36 125.6 0.2 2.1 2 0 0 2 2 2 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain STAS_2 PF13466.6 KIR61910.1 - 2.7e-07 30.8 5.7 2.7e-07 30.8 5.7 2.8 3 1 0 3 3 3 1 STAS domain STAS PF01740.21 KIR61910.1 - 2.2e-05 24.0 0.0 4.4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 STAS domain FGGY_N PF00370.21 KIR61911.1 - 4e-34 118.3 0.0 8.1e-34 117.3 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIR61911.1 - 1.6e-25 90.0 2.3 2.7e-25 89.3 2.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 KIR61911.1 - 0.21 9.7 0.0 0.3 9.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein MazG PF03819.17 KIR61913.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.4 1 1 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain DUF2597 PF10772.9 KIR61913.1 - 0.09 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) PRA-PH PF01503.17 KIR61913.1 - 0.1 13.1 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Molybdop_Fe4S4 PF04879.16 KIR61914.1 - 3.9e-18 65.2 0.8 5.6e-18 64.7 0.8 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Molybdopterin PF00384.22 KIR61915.1 - 6.5e-21 74.8 0.0 2.9e-12 46.3 0.0 2.4 2 1 0 2 2 2 2 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KIR61915.1 - 3.5e-08 33.5 0.0 1.2e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer4_11 PF13247.6 KIR61916.1 - 5.1e-23 81.1 7.4 5.1e-23 81.1 7.4 1.4 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR61916.1 - 8.8e-20 71.0 2.1 4.1e-08 33.7 0.0 3.4 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIR61916.1 - 2.4e-12 46.8 17.8 2.8e-06 27.4 8.1 3.3 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR61916.1 - 1.8e-11 44.0 20.1 1.6e-06 28.1 8.4 3.4 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIR61916.1 - 2e-09 37.0 32.2 0.0013 18.7 3.6 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4 PF00037.27 KIR61916.1 - 2e-09 36.9 40.5 4.9e-06 26.1 7.0 5.1 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_6 PF12837.7 KIR61916.1 - 8.6e-09 35.1 35.1 6.5e-06 26.0 4.4 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 KIR61916.1 - 5.6e-07 30.4 22.6 0.024 15.6 3.7 4.3 4 0 0 4 4 4 3 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 KIR61916.1 - 2e-06 28.4 38.9 0.25 12.4 5.7 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_17 PF13534.6 KIR61916.1 - 0.00025 21.5 22.4 0.79 10.3 0.3 4.3 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 KIR61916.1 - 0.001 19.4 33.1 0.017 15.6 1.4 4.5 4 1 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 KIR61916.1 - 0.0021 18.5 25.7 0.047 14.1 5.4 4.1 2 2 2 4 4 4 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KIR61916.1 - 0.0089 16.1 29.5 0.29 11.3 2.3 4.3 4 1 1 5 5 5 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KIR61916.1 - 6.3 7.0 19.4 0.52 10.5 2.8 3.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KIR61916.1 - 6.5 7.6 19.8 6.3 7.6 0.1 4.0 3 1 0 3 3 3 0 4Fe-4S single cluster domain NrfD PF03916.14 KIR61917.1 - 1e-19 71.4 2.6 1e-19 71.4 2.6 1.5 2 0 0 2 2 2 1 Polysulphide reductase, NrfD SelA PF03841.13 KIR61918.1 - 3.1e-98 329.1 0.0 3.9e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Se-cys_synth_N PF12390.8 KIR61918.1 - 7.8e-06 26.0 11.4 7.8e-06 26.0 11.4 4.8 4 2 0 4 4 4 1 Selenocysteine synthase N terminal GTP_EFTU PF00009.27 KIR61919.1 - 9.3e-22 77.5 0.0 4e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SelB-wing_3 PF09107.11 KIR61919.1 - 1e-13 50.7 0.1 2.3e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor SelB, winged helix MMR_HSR1 PF01926.23 KIR61919.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIR61919.1 - 0.0044 17.4 1.2 0.013 15.9 1.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SelB-wing_2 PF09106.11 KIR61919.1 - 0.0066 16.6 3.5 0.014 15.6 0.2 3.2 2 1 1 3 3 3 1 Elongation factor SelB, winged helix eIF2_C PF09173.11 KIR61919.1 - 0.21 11.9 0.0 0.48 10.7 0.0 1.5 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal Acyl_transf_3 PF01757.22 KIR61920.1 - 0.0092 15.1 4.3 0.0092 15.1 4.3 1.5 2 0 0 2 2 2 1 Acyltransferase family IPTL-CTERM PF18203.1 KIR61922.1 - 0.41 10.6 4.0 0.7 9.9 0.8 2.1 2 0 0 2 2 2 0 IPTL-CTERM motif DUF543 PF04418.12 KIR61925.1 - 3 7.9 6.7 0.24 11.4 1.3 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Usp PF00582.26 KIR61927.1 - 1.2e-46 158.8 16.0 1.2e-25 90.7 3.4 2.0 2 0 0 2 2 2 2 Universal stress protein family DehI PF10778.9 KIR61927.1 - 0.096 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI PGM_PMM_I PF02878.16 KIR61927.1 - 0.17 11.6 1.8 0.66 9.7 0.2 2.4 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Methyltransf_19 PF04672.12 KIR61928.1 - 2.9e-34 118.8 0.0 3.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase PsbH PF00737.20 KIR61928.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein MarR PF01047.22 KIR61929.1 - 3.2e-14 52.6 1.2 5.3e-14 51.9 0.1 1.9 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.7 KIR61929.1 - 1.7e-12 47.1 1.8 1.7e-12 47.1 1.8 2.5 2 1 0 2 2 2 1 MarR family HTH_27 PF13463.6 KIR61929.1 - 4.7e-07 30.2 0.6 7.6e-07 29.5 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KIR61929.1 - 6e-06 26.0 2.6 6.4e-06 25.9 0.5 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR61929.1 - 7.7e-06 25.4 0.9 1.3e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 KIR61929.1 - 0.0068 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KIR61929.1 - 0.0091 16.0 1.4 0.0091 16.0 1.4 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain Dimerisation2 PF16864.5 KIR61929.1 - 0.018 15.0 0.1 0.041 13.9 0.0 1.6 2 0 0 2 2 2 0 Dimerisation domain CDP-OH_P_transf PF01066.21 KIR61930.1 - 7.9e-16 58.6 0.7 7.9e-16 58.6 0.7 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4267 PF14087.6 KIR61930.1 - 9.8 6.3 12.5 84 3.3 12.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) DUF881 PF05949.12 KIR61931.1 - 9.1e-36 122.9 0.0 1.3e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) DUF1290 PF06947.12 KIR61932.1 - 5.6e-35 119.3 2.3 5.6e-35 119.3 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1290) DUF881 PF05949.12 KIR61933.1 - 1.4e-29 102.8 0.0 3e-29 101.8 0.0 1.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF881) Med11 PF10280.9 KIR61933.1 - 0.014 15.8 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 Mediator complex protein V-ATPase_G_2 PF16999.5 KIR61933.1 - 0.22 11.9 4.6 0.44 11.0 3.4 1.9 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit GCV_H PF01597.19 KIR61934.1 - 1.6e-43 147.4 0.0 1.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KIR61934.1 - 1.4e-05 24.9 0.2 2.9e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KIR61934.1 - 0.0044 17.7 0.2 0.74 10.5 0.0 2.1 2 0 0 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 KIR61934.1 - 0.0059 16.5 0.1 0.0082 16.1 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 KIR61934.1 - 0.13 12.1 0.1 4.7 7.1 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like FHA PF00498.26 KIR61935.1 - 7.2e-21 74.3 0.2 9.7e-21 73.9 0.2 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIR61935.1 - 4.5e-19 68.6 0.0 6.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MerR PF00376.23 KIR61936.1 - 4.3e-14 52.0 0.1 1.4e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 MerR family regulatory protein MerR_1 PF13411.6 KIR61936.1 - 1.8e-10 40.7 0.0 8.5e-10 38.6 0.0 2.1 3 0 0 3 3 3 1 MerR HTH family regulatory protein DNase-RNase PF02577.14 KIR61937.1 - 5.7e-45 152.1 0.1 6.7e-45 151.9 0.1 1.0 1 0 0 1 1 1 1 Bifunctional nuclease MerR_1 PF13411.6 KIR61938.1 - 3.2e-14 52.8 0.0 4.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR61938.1 - 0.0076 16.0 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 MerR family regulatory protein NAD_binding_1 PF00175.21 KIR61939.1 - 3.5e-11 43.7 0.0 9.7e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KIR61939.1 - 1.2e-08 35.5 0.0 2.9e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KIR61939.1 - 1.4e-07 31.8 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain GDC-P PF02347.16 KIR61940.1 - 6.3e-187 621.7 0.0 4.1e-175 582.7 0.0 2.2 1 1 1 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KIR61940.1 - 8.3e-06 25.0 0.2 3.8e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIR61940.1 - 5.7e-05 22.5 0.8 0.00042 19.7 0.1 2.2 2 0 0 2 2 2 1 Beta-eliminating lyase Chorismate_bind PF00425.18 KIR61942.1 - 1.8e-63 214.5 0.0 2.3e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Pep_deformylase PF01327.21 KIR61943.1 - 1.7e-37 128.5 0.0 2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Nitroreductase PF00881.24 KIR61944.1 - 2.4e-17 63.5 0.0 3.3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Exo_endo_phos PF03372.23 KIR61945.1 - 4.2e-13 49.4 2.0 6e-13 48.8 2.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_integrase PF00589.22 KIR61946.1 - 1.1e-22 80.7 0.0 1.7e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KIR61946.1 - 3.6e-08 33.6 0.0 1.3e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain adh_short_C2 PF13561.6 KIR61947.1 - 2.7e-59 200.6 3.1 3.3e-59 200.3 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR61947.1 - 9e-49 165.6 0.6 1.1e-48 165.3 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR61947.1 - 1.7e-17 63.9 1.7 2.4e-17 63.4 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR61947.1 - 1.9e-05 24.3 1.0 6.6e-05 22.5 0.4 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR61947.1 - 0.00039 19.9 0.9 0.0009 18.7 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIR61947.1 - 0.13 12.1 4.4 0.14 12.0 3.2 1.5 1 1 0 1 1 1 0 NAD(P)H-binding AhpC-TSA PF00578.21 KIR61948.1 - 2.9e-28 98.2 0.0 3.4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR61948.1 - 5.6e-15 55.3 0.0 5.9e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KIR61948.1 - 0.019 15.1 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 KIR61948.1 - 0.074 12.6 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Cyt_bd_oxida_II PF02322.15 KIR61949.1 - 6.1e-122 406.7 31.3 7e-122 406.5 31.3 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II FtsX PF02687.21 KIR61949.1 - 0.017 15.6 2.2 0.017 15.6 2.2 4.1 2 2 1 3 3 3 0 FtsX-like permease family DUF2070 PF09843.9 KIR61949.1 - 0.58 8.4 4.2 0.87 7.8 4.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyt_bd_oxida_I PF01654.17 KIR61950.1 - 1.1e-171 571.2 23.6 1.2e-171 571.0 23.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I CcmD PF04995.14 KIR61950.1 - 6.1 7.0 7.3 0.28 11.3 0.5 2.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Acyltransferase PF01553.21 KIR61951.1 - 1.1e-17 63.9 0.0 1.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GDPD PF03009.17 KIR61952.1 - 3.2e-34 118.8 0.0 2.2e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIR61952.1 - 2e-08 34.4 0.0 1.9e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PG_binding_3 PF09374.10 KIR61952.1 - 0.0069 16.6 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 Predicted Peptidoglycan domain ATG22 PF11700.8 KIR61953.1 - 8.3e-107 357.8 15.7 1.9e-104 350.0 15.7 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIR61953.1 - 1.7e-10 40.4 60.4 5.9e-08 32.0 18.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KIR61953.1 - 4.9e-07 28.7 16.7 1.1e-06 27.5 16.7 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein TK PF00265.18 KIR61954.1 - 2.9e-22 79.4 0.0 3.3e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.6 KIR61954.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF4878 PF12870.7 KIR61955.1 - 3.1e-05 24.2 0.0 0.06 13.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4878) Hva1_TUDOR PF11160.8 KIR61955.1 - 0.0059 16.8 0.5 0.01 16.0 0.5 1.4 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain DUF3828 PF12883.7 KIR61955.1 - 0.019 15.3 0.0 0.028 14.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3828) DUF4440 PF14534.6 KIR61955.1 - 0.082 13.3 2.2 0.15 12.4 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) FixH PF05751.11 KIR61955.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 FixH Endopep_inhib PF16800.5 KIR61955.1 - 0.32 10.9 0.0 0.43 10.5 0.0 1.1 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor Phage_integrase PF00589.22 KIR61956.1 - 8.2e-29 100.6 0.0 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KIR61956.1 - 3.1e-13 49.8 3.1 2.1e-10 40.8 0.2 3.5 4 0 0 4 4 4 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KIR61956.1 - 0.00011 22.6 0.0 0.00043 20.7 0.0 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 KIR61956.1 - 0.00051 20.2 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Integrase HSP20 PF00011.21 KIR61957.1 - 5.2e-16 58.6 0.0 6.2e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIR61957.1 - 1.8e-06 27.4 0.0 3.3e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA APH PF01636.23 KIR61958.1 - 3.3e-08 33.8 10.5 0.00013 22.0 3.5 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Hydrolase_4 PF12146.8 KIR61959.1 - 1.9e-06 27.3 0.9 0.03 13.6 0.6 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIR61959.1 - 3.1e-05 24.7 11.8 4.4e-05 24.2 11.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIR61959.1 - 0.00029 20.5 0.0 3.4 7.2 0.0 3.0 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KIR61959.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIR61959.1 - 0.032 13.9 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 KIR61959.1 - 0.085 11.5 0.0 5.5 5.6 0.0 2.6 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) HTH_34 PF13601.6 KIR61962.1 - 2.3e-19 69.3 0.1 2.7e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 KIR61962.1 - 9e-05 22.5 1.4 9.5e-05 22.4 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 KIR61962.1 - 0.00017 21.4 0.1 0.00033 20.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KIR61962.1 - 0.0006 19.7 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 MarR family Cdc6_C PF09079.11 KIR61962.1 - 0.00097 19.1 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain PadR PF03551.14 KIR61962.1 - 0.0011 18.8 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 KIR61962.1 - 0.0072 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 MarR family DprA_WH PF17782.1 KIR61962.1 - 0.029 14.5 0.2 0.086 13.0 0.0 1.9 2 0 0 2 2 2 0 DprA winged helix domain Rrf2 PF02082.20 KIR61962.1 - 0.05 14.0 0.1 0.089 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 KIR61962.1 - 0.057 13.9 0.1 0.086 13.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain MDMPI_N PF11716.8 KIR61964.1 - 1.5e-07 32.2 11.4 1.5e-07 32.2 11.4 1.9 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 KIR61964.1 - 1.9e-05 25.2 0.5 1.9e-05 25.2 0.5 1.6 2 0 0 2 2 2 1 DinB superfamily NUDIX PF00293.28 KIR61965.1 - 7.3e-16 58.4 0.3 9.2e-16 58.1 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain Erythro_esteras PF05139.14 KIR61966.1 - 1.6e-55 189.3 0.7 1.9e-55 189.0 0.7 1.1 1 0 0 1 1 1 1 Erythromycin esterase Phage_TAC_6 PF09550.10 KIR61966.1 - 0.044 14.2 0.2 0.15 12.5 0.2 1.9 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC DUF1992 PF09350.10 KIR61967.1 - 4.9e-18 65.1 0.1 7.6e-18 64.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) FAD_binding_4 PF01565.23 KIR61967.1 - 0.21 11.3 1.0 0.32 10.7 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Cupin_7 PF12973.7 KIR61968.1 - 3.5e-15 55.7 0.0 4.4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.6 KIR61968.1 - 0.00034 19.8 0.0 0.00039 19.6 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_2 PF07883.11 KIR61968.1 - 0.00057 19.5 0.4 0.0015 18.2 0.4 1.7 1 1 0 1 1 1 1 Cupin domain HTH_18 PF12833.7 KIR61969.1 - 8.3e-23 80.5 2.1 1.4e-22 79.7 2.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR61969.1 - 5.5e-16 58.2 0.0 1.1e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 KIR61969.1 - 9.6e-16 58.0 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 KIR61969.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain HTH_23 PF13384.6 KIR61969.1 - 0.028 14.2 0.2 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KIR61969.1 - 0.032 13.6 0.2 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 TetR_N PF00440.23 KIR61969.1 - 0.083 12.7 0.1 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 KIR61969.1 - 0.35 10.7 8.4 1.8 8.5 0.1 3.4 3 1 1 4 4 4 0 AsnC-type helix-turn-helix domain Acetyltransf_3 PF13302.7 KIR61970.1 - 6.5e-22 78.7 0.2 7.8e-22 78.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR61970.1 - 8.2e-08 32.5 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR61970.1 - 0.021 14.5 1.6 0.036 13.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 KIR61971.1 - 4.2e-34 117.7 0.2 1.3e-33 116.1 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR61971.1 - 5.8e-21 75.1 0.8 8.6e-21 74.6 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIR61971.1 - 2.4e-11 43.6 0.0 5.9e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIR61971.1 - 0.0071 16.3 0.8 4 7.3 0.0 2.3 1 1 1 2 2 2 2 KR domain CHASE2 PF05226.11 KIR61971.1 - 0.015 15.0 1.3 0.019 14.7 1.3 1.4 1 1 0 1 1 1 0 CHASE2 domain RmlD_sub_bind PF04321.17 KIR61971.1 - 0.015 14.4 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIR61971.1 - 0.24 10.7 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FMO-like PF00743.19 KIR61972.1 - 1.8e-64 218.1 0.0 2.2e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIR61972.1 - 1.5e-16 60.5 0.0 9e-14 51.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR61972.1 - 2e-14 53.5 0.0 2.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIR61972.1 - 1.5e-08 34.2 0.2 6.2e-07 28.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIR61972.1 - 0.00014 22.0 4.1 0.0002 21.5 1.4 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR61972.1 - 0.00016 21.4 13.4 1 8.9 0.0 3.4 2 1 2 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR61972.1 - 0.0031 17.5 10.0 0.12 12.3 4.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIR61972.1 - 0.02 15.4 2.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR61972.1 - 0.024 13.7 1.0 0.17 10.9 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KIR61972.1 - 0.05 12.3 3.2 1 8.0 2.1 2.8 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 KIR61972.1 - 0.061 13.8 1.0 1.6 9.2 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KIR61972.1 - 0.2 10.7 2.0 0.41 9.7 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KIR61972.1 - 1.7 7.8 3.0 0.77 9.0 0.6 1.5 2 0 0 2 2 2 0 Thi4 family Methyltransf_25 PF13649.6 KIR61973.1 - 2.7e-11 44.0 0.4 4.9e-11 43.2 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR61973.1 - 2.4e-10 40.4 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61973.1 - 9.8e-10 39.0 0.2 1.7e-09 38.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR61973.1 - 7.7e-06 25.4 0.0 3.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KIR61973.1 - 1.5e-05 24.4 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIR61973.1 - 3e-05 23.9 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61973.1 - 9.7e-05 23.0 0.0 0.00018 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIR61973.1 - 0.00025 20.7 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 KIR61973.1 - 0.0044 16.7 1.2 0.11 12.1 1.2 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 KIR61973.1 - 0.033 14.2 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIR61973.1 - 0.047 13.5 0.1 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KIR61973.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain zf-HC2 PF13490.6 KIR61973.1 - 0.075 13.3 0.6 0.16 12.3 0.6 1.6 1 0 0 1 1 1 0 Putative zinc-finger Methyltransf_15 PF09445.10 KIR61973.1 - 0.13 11.9 0.2 0.17 11.4 0.2 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MFS_2 PF13347.6 KIR61974.1 - 2.9e-59 200.7 24.8 3.3e-59 200.6 24.8 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KIR61974.1 - 1.3e-07 30.9 49.8 1.3e-07 30.9 49.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FxsA PF04186.13 KIR61976.1 - 2.6e-27 95.1 11.1 3.5e-27 94.7 11.1 1.2 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein SLATT_3 PF18184.1 KIR61976.1 - 0.16 12.1 2.6 0.26 11.4 2.6 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 CN_hydrolase PF00795.22 KIR61977.1 - 2.8e-14 53.1 0.1 4.5e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MutL PF13941.6 KIR61978.1 - 1.6e-126 422.5 13.5 1.8e-126 422.4 13.5 1.0 1 0 0 1 1 1 1 MutL protein Hydant_A_N PF05378.13 KIR61978.1 - 0.006 16.3 1.2 0.52 10.0 0.1 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region 4HBT PF03061.22 KIR61979.1 - 1.3e-07 31.9 0.4 2e-07 31.3 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KIR61979.1 - 0.0013 19.3 0.0 0.0013 19.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Lys-AminoMut_A PF09043.11 KIR61980.1 - 5.5e-244 810.3 0.0 6.3e-244 810.1 0.0 1.0 1 0 0 1 1 1 1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit OAM_alpha PF16552.5 KIR61980.1 - 8.4e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 D-ornithine 4,5-aminomutase alpha-subunit AP_endonuc_2 PF01261.24 KIR61982.1 - 0.025 14.0 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Radical_SAM PF04055.21 KIR61982.1 - 0.028 14.8 0.0 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily Amidase_2 PF01510.25 KIR61983.1 - 1e-11 45.3 0.8 1.8e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 N-acetylmuramoyl-L-alanine amidase CsbD PF05532.12 KIR61984.1 - 1.5e-14 53.6 8.4 1.8e-14 53.4 8.4 1.1 1 0 0 1 1 1 1 CsbD-like DUF883 PF05957.13 KIR61984.1 - 0.0091 16.6 4.8 0.01 16.4 4.8 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 KIR61984.1 - 0.069 13.3 2.9 0.069 13.3 2.9 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant protein His_Phos_1 PF00300.22 KIR61985.1 - 1.1e-45 155.8 3.1 1.2e-45 155.6 3.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Plasmid_stab_B PF10784.9 KIR61985.1 - 0.018 14.9 0.4 0.049 13.5 0.4 1.7 1 0 0 1 1 1 0 Plasmid stability protein HTH_24 PF13412.6 KIR61986.1 - 8.7e-18 63.6 0.1 1.4e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KIR61986.1 - 1.8e-17 62.9 0.5 4.6e-17 61.6 0.5 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KIR61986.1 - 7.7e-13 48.2 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 KIR61986.1 - 4.3e-06 26.5 1.7 4.9e-06 26.3 0.5 1.7 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 KIR61986.1 - 2e-05 24.6 0.8 2e-05 24.6 0.8 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_20 PF12840.7 KIR61986.1 - 2.5e-05 24.2 0.6 5.1e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 KIR61986.1 - 3.2e-05 23.8 1.0 0.0001 22.2 0.0 2.2 2 1 1 3 3 3 1 HTH domain HTH_IclR PF09339.10 KIR61986.1 - 3.2e-05 23.6 0.2 6.2e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 KIR61986.1 - 6.4e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 KIR61986.1 - 0.00044 20.0 0.4 0.00096 18.9 0.4 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR61986.1 - 0.00083 19.0 0.5 0.0063 16.2 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KIR61986.1 - 0.00091 19.2 0.4 0.0021 18.0 0.1 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_47 PF16221.5 KIR61986.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix HTH_1 PF00126.27 KIR61986.1 - 0.0072 16.2 0.1 0.02 14.8 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 KIR61986.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_9 PF08221.11 KIR61986.1 - 0.0078 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 KIR61986.1 - 0.0087 15.9 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 KIR61986.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_10 PF04967.12 KIR61986.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Mga PF08280.11 KIR61986.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4 PF04545.16 KIR61986.1 - 0.021 14.3 0.2 0.039 13.5 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_CodY PF08222.11 KIR61986.1 - 0.022 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR61986.1 - 0.036 13.5 0.1 0.063 12.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 KIR61986.1 - 0.05 13.9 0.1 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Fe_dep_repress PF01325.19 KIR61986.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 KIR61986.1 - 0.21 11.5 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Acyl-CoA_dh_1 PF00441.24 KIR61987.1 - 2.6e-45 154.3 6.9 4.4e-45 153.6 6.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR61987.1 - 5.3e-24 84.2 0.0 1.1e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIR61987.1 - 2.3e-22 79.7 7.8 4.8e-22 78.7 7.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR61987.1 - 4e-20 72.6 0.1 1e-19 71.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3040 PF11239.8 KIR61988.1 - 0.0013 19.0 7.7 0.0019 18.4 7.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3040) YwiC PF14256.6 KIR61988.1 - 0.0014 19.0 3.9 0.0016 18.8 3.9 1.0 1 0 0 1 1 1 1 YwiC-like protein DUF3483 PF11982.8 KIR61988.1 - 0.0084 15.8 3.4 0.0092 15.6 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) FA_desaturase PF00487.24 KIR61988.1 - 0.028 14.3 1.1 0.03 14.2 1.1 1.0 1 0 0 1 1 1 0 Fatty acid desaturase DUF4191 PF13829.6 KIR61988.1 - 0.039 13.3 0.8 0.047 13.0 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) IgaA PF07095.11 KIR61988.1 - 0.16 10.0 0.1 0.16 9.9 0.1 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF3357 PF11837.8 KIR61988.1 - 0.24 11.9 5.8 2.7 8.5 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF2892 PF11127.8 KIR61988.1 - 0.94 9.6 11.9 1.3 9.1 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) ATP1G1_PLM_MAT8 PF02038.16 KIR61988.1 - 0.94 9.0 2.6 1.6 8.2 2.6 1.5 1 1 0 1 1 1 0 ATP1G1/PLM/MAT8 family PhoR PF11808.8 KIR61988.1 - 1 9.8 7.6 1.4 9.4 7.6 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR 5_3_exonuc_N PF02739.16 KIR61989.1 - 1.4e-44 151.8 0.0 1.7e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 KIR61989.1 - 5.1e-19 68.7 0.0 7.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KIR61989.1 - 0.021 14.9 0.3 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH PF00633.23 KIR61989.1 - 0.049 13.5 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KIR61989.1 - 0.071 13.7 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain MHYT PF03707.16 KIR61990.1 - 1.3e-39 134.2 45.4 4.9e-16 58.6 13.9 4.3 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DSHCT PF08148.12 KIR61991.1 - 2e-38 131.6 0.0 4.2e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KIR61991.1 - 1.6e-17 63.9 0.0 2.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 KIR61991.1 - 3.6e-08 33.7 0.0 3.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 rRNA-processing arch domain ResIII PF04851.15 KIR61991.1 - 1.6e-06 28.2 0.0 2.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIR61991.1 - 0.0014 18.9 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_C PF00271.31 KIR61991.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Trp_dioxygenase PF03301.13 KIR61992.1 - 2.7e-20 73.0 0.0 2.3e-14 53.5 0.0 2.0 1 1 0 2 2 2 2 Tryptophan 2,3-dioxygenase DUF5609 PF18429.1 KIR61992.1 - 0.14 12.0 0.0 0.76 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5609) EccE PF11203.8 KIR61992.1 - 0.62 10.4 7.0 0.8 10.1 2.0 2.2 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Methyltransf_2 PF00891.18 KIR61993.1 - 8.8e-23 80.7 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 KIR61993.1 - 1.6e-05 25.5 0.0 2.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR61993.1 - 1.8e-05 25.4 0.0 3.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61993.1 - 7.4e-05 23.4 0.0 0.00014 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR61993.1 - 0.00014 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KIR61993.1 - 0.0041 17.0 0.0 0.0091 15.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MarR_2 PF12802.7 KIR61993.1 - 0.0064 16.4 0.0 0.022 14.7 0.0 2.0 1 0 0 1 1 1 1 MarR family Dimerisation2 PF16864.5 KIR61993.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain TrmB PF01978.19 KIR61993.1 - 0.027 14.3 0.0 0.19 11.6 0.0 2.3 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB Methyltransf_2 PF00891.18 KIR61994.1 - 4.5e-42 143.7 0.0 5.7e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KIR61994.1 - 2.5e-12 46.6 0.0 1.6e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_25 PF13649.6 KIR61994.1 - 1.6e-09 38.4 0.0 3.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR61994.1 - 2.5e-07 30.7 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR61994.1 - 3.8e-06 27.6 0.0 6.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR61994.1 - 2.3e-05 25.0 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR61994.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KIR61994.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 KIR61994.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Sigma70_r4_2 PF08281.12 KIR61995.1 - 1e-15 57.1 0.3 2.5e-15 55.9 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR61995.1 - 2.5e-15 56.0 0.1 6.2e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR61995.1 - 1.1e-06 28.0 0.0 2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR61995.1 - 0.00025 21.0 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 KIR61995.1 - 0.0013 18.5 0.1 0.0032 17.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KIR61995.1 - 0.032 14.3 0.2 0.15 12.2 0.2 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain HAMP PF00672.25 KIR61996.1 - 2.6e-10 40.5 1.5 2.6e-10 40.5 1.5 3.8 4 1 0 4 4 4 1 HAMP domain HATPase_c PF02518.26 KIR61996.1 - 4.8e-09 36.7 0.0 1.1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR61996.1 - 1.7e-06 28.0 0.9 1.7e-06 28.0 0.9 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KIR61996.1 - 0.0037 17.2 0.1 0.012 15.6 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PilJ PF13675.6 KIR61996.1 - 0.023 14.7 2.1 0.058 13.4 2.1 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term T3SS_needle_E PF08988.10 KIR61996.1 - 0.27 11.4 2.9 0.66 10.2 1.8 2.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Trans_reg_C PF00486.28 KIR61997.1 - 7.3e-25 86.9 0.1 1.9e-24 85.5 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KIR61997.1 - 9.1e-24 83.8 0.2 1.2e-23 83.4 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain MarR_2 PF12802.7 KIR61997.1 - 0.014 15.2 0.0 0.043 13.7 0.0 1.9 1 0 0 1 1 1 0 MarR family YlzJ PF14035.6 KIR61997.1 - 0.049 13.8 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 YlzJ-like protein GerE PF00196.19 KIR61997.1 - 0.18 11.4 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Lipase_GDSL_2 PF13472.6 KIR61997.1 - 0.23 11.8 1.8 0.23 11.9 0.7 1.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family RhodobacterPufX PF11511.8 KIR61998.1 - 2.8 7.6 5.5 0.57 9.8 2.0 1.6 2 0 0 2 2 2 0 Intrinsic membrane protein PufX SIP PF04954.13 KIR61999.1 - 2.1e-41 141.2 0.1 3.3e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 KIR61999.1 - 5.4e-36 123.5 0.0 8.2e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Acetyltransf_8 PF13523.6 KIR62000.1 - 1.7e-49 167.3 0.1 2e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR62000.1 - 6.7e-06 26.8 0.0 9.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBM_20 PF00686.19 KIR62001.1 - 1.1e-58 195.2 3.3 5.3e-32 109.6 0.7 2.7 2 0 0 2 2 2 2 Starch binding domain Alpha-amylase PF00128.24 KIR62001.1 - 8.7e-20 71.5 0.0 1.5e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain PT PF04886.12 KIR62001.1 - 0.16 11.5 18.9 0.36 10.4 18.9 1.5 1 0 0 1 1 1 0 PT repeat SIP PF04954.13 KIR62002.1 - 9e-22 77.8 1.1 1.3e-21 77.3 1.1 1.2 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 KIR62002.1 - 1.6e-10 41.2 0.2 3.8e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Acetyltransf_8 PF13523.6 KIR62003.1 - 6.6e-51 171.8 0.1 7.7e-51 171.6 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR62003.1 - 3.9e-06 27.6 0.0 5.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PQQ_2 PF13360.6 KIR62004.1 - 4.7e-07 29.6 1.4 7.9e-06 25.6 0.1 2.5 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KIR62004.1 - 3.6e-06 26.6 0.0 0.079 12.9 0.0 3.8 3 0 0 3 3 3 2 PQQ enzyme repeat Lactonase PF10282.9 KIR62004.1 - 0.015 14.6 0.0 0.92 8.7 0.0 2.7 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 KIR62004.1 - 0.06 13.9 1.0 1.5 9.4 0.1 3.6 3 0 0 3 3 3 0 PQQ-like domain Trypsin PF00089.26 KIR62005.1 - 5.9e-50 170.1 0.8 6.8e-50 169.9 0.8 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KIR62005.1 - 1.3e-08 35.9 0.6 2.3e-08 35.1 0.6 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S8 PF00082.22 KIR62006.1 - 2.2e-10 40.3 2.6 1.3e-09 37.7 2.6 2.0 1 1 0 1 1 1 1 Subtilase family Sigma70_r2 PF04542.14 KIR62007.1 - 1.5e-10 40.7 3.1 2.5e-10 40.0 3.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR62007.1 - 2.6e-06 26.8 0.0 5.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 KIR62007.1 - 0.0002 21.1 0.0 0.00082 19.2 0.0 2.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIR62007.1 - 0.00095 18.8 0.3 0.04 13.6 0.0 3.3 3 1 0 3 3 3 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR62007.1 - 0.0013 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_16 PF12645.7 KIR62007.1 - 0.055 13.5 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CPSase_L_D2 PF02786.17 KIR62008.1 - 5.2e-61 205.8 0.0 8.9e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KIR62008.1 - 2.1e-35 121.1 0.0 6.3e-35 119.5 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Carboxyl_trans PF01039.22 KIR62008.1 - 1.4e-33 116.3 0.1 2.5e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain Biotin_carb_N PF00289.22 KIR62008.1 - 9.4e-33 113.1 0.0 2.4e-32 111.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain ACC_central PF08326.12 KIR62008.1 - 6.6e-13 47.8 0.0 2.7e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 KIR62008.1 - 1.1e-09 38.0 0.0 2.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KIR62008.1 - 3.7e-09 36.4 0.0 1.1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIR62008.1 - 9.8e-08 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KIR62008.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KIR62008.1 - 0.007 16.5 0.1 0.074 13.2 0.1 3.0 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_5 PF13549.6 KIR62008.1 - 0.025 14.0 0.0 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.6 KIR62008.1 - 0.025 15.3 0.2 4.8 7.9 0.0 3.4 3 0 0 3 3 3 0 HlyD family secretion protein Condensation PF00668.20 KIR62009.1 - 3.9e-26 91.8 0.0 9.2e-15 54.3 0.0 2.3 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 KIR62010.1 - 3.8e-70 236.6 0.2 5e-70 236.2 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR62010.1 - 4.4e-17 62.8 0.6 1.2e-16 61.4 0.6 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIR62011.1 - 3.4e-95 319.1 0.1 4.7e-95 318.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR62011.1 - 3.4e-40 138.1 0.0 1e-39 136.5 0.0 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KIR62011.1 - 5e-19 68.4 0.2 1.6e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR62011.1 - 5.4e-10 40.1 1.9 1.7e-08 35.3 0.0 3.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR62012.1 - 4.1e-07 30.2 0.7 7.9e-07 29.3 0.7 1.5 1 1 0 1 1 1 1 Phosphopantetheine attachment site DUF4233 PF14017.6 KIR62013.1 - 0.049 14.0 12.1 0.067 13.5 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) PTS_EIIC PF02378.18 KIR62013.1 - 0.068 12.2 7.3 0.081 11.9 7.3 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Sua5_yciO_yrdC PF01300.18 KIR62014.1 - 9.8e-43 145.7 0.0 1.1e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination ThiP_synth PF10120.9 KIR62014.1 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Thiamine-phosphate synthase WD40 PF00400.32 KIR62015.1 - 3.9e-13 49.7 0.9 0.00096 19.9 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIR62015.1 - 0.0011 19.3 0.0 6.8 7.1 0.0 3.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIR62015.1 - 0.0049 15.6 0.0 0.89 8.1 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Neocarzinostat PF00960.18 KIR62016.1 - 1.6e-11 44.2 2.5 1.2e-06 28.5 0.1 2.3 2 0 0 2 2 2 2 Neocarzinostatin family Mur_ligase_M PF08245.12 KIR62017.1 - 1.6e-15 57.6 0.0 2.8e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KIR62017.1 - 8e-11 42.1 0.0 2.1e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Sigma70_r2 PF04542.14 KIR62018.1 - 7.6e-13 48.0 2.0 1.7e-12 46.9 2.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR62018.1 - 8.3e-09 35.0 0.3 8.3e-09 35.0 0.3 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 KIR62018.1 - 1.6e-05 25.5 1.3 1.6e-05 25.5 1.3 2.0 2 1 0 2 2 2 1 SnoaL-like domain Sigma70_r4 PF04545.16 KIR62018.1 - 4.5e-05 22.9 1.4 4.9e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_3 PF13474.6 KIR62018.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIR62018.1 - 0.0096 16.3 0.2 0.023 15.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) TPR_12 PF13424.6 KIR62018.1 - 0.043 14.1 1.9 0.043 14.1 1.9 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2344 PF10105.9 KIR62019.1 - 3.8e-31 108.3 0.0 4.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) DUF3652 PF12372.8 KIR62019.1 - 0.16 11.9 0.1 5.3 7.0 0.1 2.9 3 0 0 3 3 3 0 Huntingtin protein region Competence PF03772.16 KIR62020.1 - 1.4e-52 178.7 23.7 1.4e-52 178.7 23.7 2.1 2 0 0 2 2 2 1 Competence protein Lactamase_B PF00753.27 KIR62020.1 - 8.9e-09 35.6 2.0 8.9e-09 35.6 2.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF4131 PF13567.6 KIR62020.1 - 2.3e-07 30.6 4.0 2.3e-07 30.6 4.0 5.2 4 2 1 5 5 5 1 Domain of unknown function (DUF4131) Lactamase_B_2 PF12706.7 KIR62020.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain APH PF01636.23 KIR62021.1 - 1.3e-12 48.2 14.4 1.3e-12 48.2 14.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family BPD_transp_1 PF00528.22 KIR62022.1 - 5.7e-23 81.6 17.5 5.7e-23 81.6 17.5 1.7 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2970 PF11174.8 KIR62023.1 - 0.029 14.2 3.6 2.5 8.0 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Radical_SAM PF04055.21 KIR62024.1 - 4.4e-21 76.0 0.0 6.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 KIR62024.1 - 0.013 15.5 0.2 0.16 12.0 0.2 2.5 2 1 0 2 2 2 0 HemN C-terminal domain DUF21 PF01595.20 KIR62025.1 - 8.3e-32 110.3 1.7 1.2e-31 109.7 1.7 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIR62025.1 - 4.4e-15 55.9 0.9 5.6e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 KIR62025.1 - 1.5e-14 53.8 0.2 1.5e-13 50.5 0.2 2.3 2 0 0 2 2 2 1 Transporter associated domain Beta_protein PF14350.6 KIR62025.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta protein MMR_HSR1 PF01926.23 KIR62026.1 - 5.1e-19 68.5 0.0 8.7e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 KIR62026.1 - 3.6e-15 55.5 0.1 6.4e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 KH domain RsgA_GTPase PF03193.16 KIR62026.1 - 2.6e-10 40.5 0.0 3.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIR62026.1 - 1.5e-09 37.6 0.2 6.8e-09 35.4 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIR62026.1 - 1.5e-08 34.9 0.1 0.00018 21.6 0.2 2.2 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.9 KIR62026.1 - 1.4e-06 28.1 0.0 4.7e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 KIR62026.1 - 3.5e-06 26.7 0.2 0.0017 17.9 0.2 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KIR62026.1 - 4.9e-05 22.7 0.0 0.00011 21.6 0.0 1.5 2 0 0 2 2 2 1 AIG1 family DUF2773 PF10971.8 KIR62026.1 - 0.07 13.3 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) ABC_tran PF00005.27 KIR62026.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter DUF4097 PF13349.6 KIR62027.1 - 7.6e-12 45.1 0.1 1.7e-11 44.0 0.1 1.7 1 1 0 1 1 1 1 Putative adhesin Abhydrolase_1 PF00561.20 KIR62028.1 - 7.1e-25 88.1 0.1 3.9e-24 85.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR62028.1 - 4.6e-17 63.4 22.1 5.4e-17 63.1 22.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR62028.1 - 1e-12 47.9 0.7 4.1e-12 45.9 0.7 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 KIR62028.1 - 0.041 13.3 0.2 0.056 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Thioesterase PF00975.20 KIR62028.1 - 0.043 13.9 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 KIR62028.1 - 0.29 9.8 0.0 0.4 9.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family FixH PF05751.11 KIR62030.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 FixH Dus PF01207.17 KIR62031.1 - 1.1e-98 330.2 0.0 1.4e-98 329.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 KIR62031.1 - 0.0035 16.4 0.1 0.0058 15.7 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TatD_DNase PF01026.21 KIR62032.1 - 3.3e-11 43.1 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase PTE PF02126.18 KIR62032.1 - 3.6e-05 23.3 0.0 0.00089 18.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotriesterase family GSDH PF07995.11 KIR62033.1 - 4e-34 118.4 0.0 3.8e-33 115.2 0.0 2.4 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase RicinB_lectin_2 PF14200.6 KIR62033.1 - 2.7e-32 111.3 18.8 1.2e-14 54.8 3.2 4.6 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CBM_6 PF03422.15 KIR62033.1 - 4.5e-32 111.0 4.3 4.5e-32 111.0 4.3 3.1 3 0 0 3 3 3 1 Carbohydrate binding module (family 6) Ricin_B_lectin PF00652.22 KIR62033.1 - 2e-31 108.9 7.0 3.7e-31 108.0 7.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PKD PF00801.20 KIR62033.1 - 8.7e-11 41.5 3.2 8.7e-11 41.5 3.2 3.5 4 1 0 4 4 4 1 PKD domain DUF5010_C PF18099.1 KIR62033.1 - 2.2e-06 27.8 0.7 8.1e-06 25.9 0.7 2.0 1 0 0 1 1 1 1 DUF5010 C-terminal domain Big_7 PF17957.1 KIR62033.1 - 1.6e-05 25.6 0.3 1.6e-05 25.6 0.3 4.3 4 1 0 4 4 4 1 Bacterial Ig domain DUF4625 PF15418.6 KIR62033.1 - 0.1 12.8 0.4 0.74 10.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4625) DUF5016 PF16408.5 KIR62033.1 - 0.18 11.8 0.7 1.5 8.8 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5016) ET PF01684.16 KIR62033.1 - 0.78 10.1 3.7 36 4.8 0.1 3.6 1 1 2 3 3 3 0 ET module FecCD PF01032.18 KIR62034.1 - 1e-84 284.2 33.6 1.2e-84 284.0 33.6 1.0 1 0 0 1 1 1 1 FecCD transport family NMT1 PF09084.11 KIR62035.1 - 1.4e-51 175.5 0.0 1.6e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KIR62035.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 NMT1-like family LysR_substrate PF03466.20 KIR62035.1 - 0.018 14.4 1.2 0.027 13.8 1.2 1.2 1 0 0 1 1 1 0 LysR substrate binding domain FtsX PF02687.21 KIR62036.1 - 6.7e-15 55.3 7.1 2.7e-11 43.8 0.3 5.8 7 1 0 7 7 7 2 FtsX-like permease family AlaE PF06610.13 KIR62036.1 - 0.01 15.9 2.5 0.056 13.5 0.8 2.7 2 0 0 2 2 2 0 L-alanine exporter FAD_binding_4 PF01565.23 KIR62037.1 - 1.3e-18 67.1 1.6 2.3e-18 66.2 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KIR62037.1 - 1.3e-18 67.8 0.0 2.1e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_5 PF00941.21 KIR62037.1 - 0.0023 17.7 0.7 0.0051 16.6 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Androgen_recep PF02166.16 KIR62037.1 - 0.021 13.7 1.8 0.05 12.5 1.8 1.6 1 0 0 1 1 1 0 Androgen receptor Hydrolase_4 PF12146.8 KIR62038.1 - 1.5e-07 31.0 0.1 0.0001 21.7 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KIR62038.1 - 3.7e-06 26.6 0.0 1.6e-05 24.6 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIR62038.1 - 8e-05 22.2 1.7 0.0019 17.7 0.2 2.8 2 2 2 4 4 4 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 KIR62038.1 - 9.2e-05 21.1 0.0 0.0067 15.0 0.0 2.3 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KIR62038.1 - 0.007 16.0 0.2 0.22 11.1 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIR62038.1 - 0.0084 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KIR62038.1 - 0.036 13.9 0.3 0.1 12.4 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.14 KIR62038.1 - 0.1 11.9 0.7 0.24 10.7 0.6 1.6 1 1 0 1 1 1 0 Secretory lipase Abhydrolase_5 PF12695.7 KIR62038.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIR62038.1 - 0.13 11.8 1.6 1.1 8.9 1.7 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KIR62039.1 - 7.2e-53 179.2 0.1 1.3e-52 178.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KIR62039.1 - 2.4e-21 76.1 0.0 8.8e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_3 PF07859.13 KIR62039.1 - 0.00021 21.2 0.7 0.00057 19.8 0.7 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR62039.1 - 0.00061 19.1 0.3 0.79 8.9 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KIR62039.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Tannase PF07519.11 KIR62039.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Esterase_phd PF10503.9 KIR62039.1 - 0.0074 15.8 0.5 0.075 12.5 0.2 2.5 2 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_4 PF08386.10 KIR62039.1 - 0.0089 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 KIR62039.1 - 0.33 10.8 0.5 19 5.1 0.0 2.5 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DivIVA PF05103.13 KIR62040.1 - 3.9e-05 23.7 0.0 4.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 DivIVA protein Herpes_UL36 PF03586.13 KIR62040.1 - 0.055 12.8 1.1 0.069 12.5 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Mre11_DNA_bind PF04152.14 KIR62040.1 - 0.11 12.8 0.2 0.12 12.7 0.2 1.1 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain AhpC-TSA PF00578.21 KIR62041.1 - 8.6e-11 41.8 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR62041.1 - 9.6e-10 38.4 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KIR62041.1 - 3.3e-06 27.3 0.0 4.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KIR62041.1 - 5e-05 23.2 0.0 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIR62041.1 - 0.01 16.3 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain MerR_1 PF13411.6 KIR62042.1 - 2.3e-13 50.0 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein DNA_pol3_beta_2 PF02767.16 KIR62042.1 - 1e-12 48.2 0.0 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III beta subunit, central domain MerR PF00376.23 KIR62042.1 - 1.7e-12 46.9 0.1 3.6e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 MerR family regulatory protein DNA_pol3_beta PF00712.19 KIR62042.1 - 7.9e-08 32.5 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 KIR62042.1 - 0.00065 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III beta subunit, C-terminal domain MerR-DNA-bind PF09278.11 KIR62042.1 - 0.0054 17.2 1.6 0.013 16.0 1.6 1.7 1 0 0 1 1 1 1 MerR, DNA binding T2SSF PF00482.23 KIR62042.1 - 0.2 11.6 1.5 0.4 10.6 1.5 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ADH_N PF08240.12 KIR62043.1 - 4.9e-23 81.1 1.4 1.2e-22 79.8 1.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR62043.1 - 3.7e-15 56.1 0.3 3.2e-09 36.9 0.1 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KIR62043.1 - 0.0008 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KIR62043.1 - 0.0029 16.9 0.5 0.0051 16.1 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIR62043.1 - 0.054 12.9 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIR62043.1 - 0.07 13.0 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIR62043.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIR62043.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KIR62043.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KIR62043.1 - 0.19 10.4 0.3 0.25 10.0 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein NADH_4Fe-4S PF10589.9 KIR62043.1 - 1.5 8.9 5.9 6.4 6.9 4.3 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PetG PF02529.15 KIR62044.1 - 0.047 13.5 0.2 0.18 11.7 0.2 2.0 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF1435 PF07256.12 KIR62044.1 - 0.053 13.6 3.9 2 8.6 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) CBM_2 PF00553.19 KIR62045.1 - 4.1e-27 94.5 12.8 1.6e-26 92.6 12.8 2.1 1 0 0 1 1 1 1 Cellulose binding domain Sortilin-Vps10 PF15902.5 KIR62045.1 - 7.4e-14 51.4 6.8 0.0023 16.8 0.1 6.5 3 2 2 6 6 6 6 Sortilin, neurotensin receptor 3, BNR PF02012.20 KIR62045.1 - 3.2e-08 32.4 38.4 0.37 11.0 1.5 9.7 9 0 0 9 9 9 5 BNR/Asp-box repeat BNR_6 PF15899.5 KIR62045.1 - 1.5e-06 27.7 3.2 0.11 12.6 0.0 6.8 6 0 0 6 6 6 1 BNR-Asp box repeat Kelch_6 PF13964.6 KIR62045.1 - 0.0008 19.6 2.3 0.0016 18.6 0.1 2.8 3 0 0 3 3 3 1 Kelch motif End_N_terminal PF12218.8 KIR62045.1 - 0.029 14.0 0.0 0.84 9.4 0.0 3.3 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Kelch_3 PF13415.6 KIR62045.1 - 0.036 14.3 5.4 0.056 13.7 0.4 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain BNR_2 PF13088.6 KIR62045.1 - 0.25 10.6 11.9 1.5 8.0 2.7 4.9 4 2 0 4 4 4 0 BNR repeat-like domain Cation_efflux PF01545.21 KIR62046.1 - 3.7e-43 147.6 11.8 4.6e-43 147.3 11.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIR62046.1 - 0.14 12.3 0.4 0.25 11.5 0.4 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter BPD_transp_1 PF00528.22 KIR62047.1 - 1.3e-32 113.1 35.4 4.3e-20 72.2 14.4 3.3 3 1 1 4 4 4 2 Binding-protein-dependent transport system inner membrane component ROK PF00480.20 KIR62048.1 - 1.3e-32 113.5 0.0 1.8e-32 113.0 0.0 1.2 1 1 0 1 1 1 1 ROK family Glucokinase PF02685.16 KIR62048.1 - 0.0017 17.4 0.2 0.0044 16.1 0.2 1.6 1 1 0 1 1 1 1 Glucokinase Amidohydro_1 PF01979.20 KIR62050.1 - 3.7e-24 85.7 0.1 1.8e-23 83.4 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIR62050.1 - 4.6e-22 79.1 0.5 2.1e-17 63.8 0.1 2.2 1 1 1 2 2 2 2 Amidohydrolase family CopC PF04234.12 KIR62051.1 - 5.8e-19 68.9 0.0 9.7e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 CopC domain DUF2892 PF11127.8 KIR62051.1 - 4.6 7.4 8.7 0.73 9.9 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) UPF0047 PF01894.17 KIR62052.1 - 3.4e-24 85.2 0.0 3.9e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RecA_dep_nuc PF16786.5 KIR62052.1 - 0.12 12.6 0.0 4.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Recombination enhancement, RecA-dependent nuclease TetR_C_31 PF17940.1 KIR62053.1 - 1.2e-19 70.5 6.8 1.2e-19 70.5 6.8 2.8 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR62053.1 - 1.1e-07 31.5 1.5 1.3e-07 31.3 0.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family ApbE PF02424.15 KIR62054.1 - 2.1e-42 145.4 0.4 7.5e-31 107.6 2.0 2.0 1 1 1 2 2 2 2 ApbE family SPOR PF05036.13 KIR62055.1 - 0.079 13.4 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Sporulation related domain Peptidase_S66 PF02016.15 KIR62056.1 - 5.1e-34 117.0 0.0 7.4e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 KIR62056.1 - 6.1e-32 110.8 0.0 8.2e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain GATase PF00117.28 KIR62057.1 - 3.4e-13 49.8 0.0 4.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIR62057.1 - 0.00044 20.1 0.2 0.00088 19.1 0.2 1.6 1 1 0 1 1 1 1 Peptidase C26 RDD PF06271.12 KIR62058.1 - 5.1e-09 36.5 5.5 6.5e-08 32.9 5.5 2.4 1 1 0 1 1 1 1 RDD family Radical_SAM PF04055.21 KIR62059.1 - 1e-12 48.7 0.0 4.1e-12 46.8 0.0 1.8 1 1 1 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 KIR62059.1 - 4.1e-05 24.0 0.1 7.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family BPL_LplA_LipB PF03099.19 KIR62060.1 - 1.1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CobS PF02654.15 KIR62062.1 - 1.9e-46 158.9 31.4 2.1e-46 158.7 31.4 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase ATP-synt_J PF04911.12 KIR62062.1 - 6.9 6.3 5.8 0.81 9.3 0.4 2.3 2 1 0 2 2 2 0 ATP synthase j chain ThiF PF00899.21 KIR62063.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 ThiF family NTP_transferase PF00483.23 KIR62064.1 - 1.5e-10 41.1 0.0 4.6e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR62064.1 - 1.9e-10 41.3 8.8 2.3e-10 41.1 7.9 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KIR62064.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RNase_T PF00929.24 KIR62065.1 - 2.7e-32 112.6 0.0 4.1e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KIR62065.1 - 3.4e-05 23.9 0.0 0.0041 17.1 0.0 2.2 2 0 0 2 2 2 2 3' exoribonuclease, RNase T-like GIY-YIG PF01541.24 KIR62065.1 - 4.9e-05 23.5 0.0 8.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 KIR62065.1 - 0.0022 17.6 1.8 0.17 11.7 0.4 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif EAL PF00563.20 KIR62066.1 - 1.8e-66 224.1 0.0 5.4e-66 222.5 0.0 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 KIR62066.1 - 9.7e-41 139.2 0.0 2.2e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain AMP-binding PF00501.28 KIR62067.1 - 4.4e-99 331.9 0.1 5.3e-99 331.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR62067.1 - 0.0031 18.5 2.2 0.024 15.6 0.3 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Exo_endo_phos PF03372.23 KIR62069.1 - 2.9e-06 27.0 3.2 6.2e-06 25.9 3.2 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_6 PF12697.7 KIR62070.1 - 6.6e-17 62.8 26.7 7.9e-17 62.6 26.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR62070.1 - 2.8e-13 49.7 1.2 3.2e-12 46.2 1.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR62070.1 - 7.5e-12 45.4 0.5 1.6e-09 37.8 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KIR62070.1 - 0.0029 17.5 0.1 0.2 11.5 0.1 2.3 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 KIR62070.1 - 0.0085 16.2 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Glyco_transf_20 PF00982.21 KIR62071.1 - 7.4e-141 470.1 0.0 8.6e-141 469.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KIR62071.1 - 0.003 17.1 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 GGDEF_2 PF17853.1 KIR62071.1 - 0.0072 16.6 6.3 0.34 11.2 0.2 3.2 2 1 1 3 3 3 2 GGDEF-like domain TetR_C_28 PF17937.1 KIR62071.1 - 0.72 10.4 5.6 1.2 9.6 0.2 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Guanylate_cyc PF00211.20 KIR62072.1 - 1.5e-26 93.1 0.0 2.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KIR62072.1 - 1.8e-17 64.2 0.1 1.8e-17 64.2 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KIR62072.1 - 0.0019 18.5 0.0 0.016 15.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain SNAP PF14938.6 KIR62072.1 - 0.0036 16.8 3.9 0.11 11.9 0.4 2.4 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP ATPase_2 PF01637.18 KIR62072.1 - 0.024 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KIR62072.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 KIR62072.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KIR62072.1 - 0.23 10.6 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KIR62072.1 - 0.28 10.9 0.0 0.28 10.9 0.0 3.5 5 0 0 5 5 5 0 AAA domain PFK PF00365.20 KIR62073.1 - 3.2e-105 351.5 0.4 3.7e-105 351.3 0.4 1.0 1 0 0 1 1 1 1 Phosphofructokinase NRD1_2 PF01995.16 KIR62073.1 - 0.0051 16.1 0.1 0.0085 15.4 0.1 1.3 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 NUDIX PF00293.28 KIR62074.1 - 1.2e-22 80.4 0.2 1.5e-22 80.1 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 KIR62074.1 - 0.23 11.0 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase NAD_binding_1 PF00175.21 KIR62075.1 - 3.6e-13 50.1 0.0 6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIR62075.1 - 4.3e-05 23.8 0.0 0.00017 21.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Rv2175c_C PF18367.1 KIR62077.1 - 8.2e-23 80.3 0.2 1.3e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function HTH_17 PF12728.7 KIR62077.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2384 PF09722.10 KIR62077.1 - 0.01 15.8 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) HTH_IclR PF09339.10 KIR62077.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR62077.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r3 PF04539.16 KIR62077.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 Caroten_synth PF04240.12 KIR62078.1 - 1.4e-37 129.6 25.0 2.2e-37 128.9 24.9 1.4 1 1 0 1 1 1 1 Carotenoid biosynthesis protein tRNA_edit PF04073.15 KIR62079.1 - 1.3e-28 99.6 0.8 1.4e-28 99.4 0.2 1.4 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain ApbE PF02424.15 KIR62080.1 - 5.1e-39 134.4 0.0 6.4e-30 104.5 0.1 2.0 1 1 1 2 2 2 2 ApbE family HTH_31 PF13560.6 KIR62081.1 - 4.5e-10 39.7 1.6 4.5e-10 39.7 1.6 3.8 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62081.1 - 2.6e-05 24.2 0.1 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix DUF58 PF01882.18 KIR62082.1 - 3.5e-22 78.5 2.1 7.4e-22 77.4 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF58 SNARE_assoc PF09335.11 KIR62083.1 - 2.6e-16 60.2 10.8 2.6e-16 60.2 10.8 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein TetR_C_16 PF17920.1 KIR62083.1 - 0.36 11.1 6.8 1.2 9.3 2.0 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Leader_Trp PF08255.11 KIR62083.1 - 2 8.6 4.8 0.86 9.7 1.7 2.1 2 0 0 2 2 2 0 Trp-operon Leader Peptide RseC_MucC PF04246.12 KIR62083.1 - 7.7 6.5 5.6 39 4.2 2.3 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Methyltransf_5 PF01795.19 KIR62084.1 - 3.6e-105 351.9 0.0 4.1e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 KIR62084.1 - 0.24 11.2 0.0 1.9 8.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FTSW_RODA_SPOVE PF01098.19 KIR62085.1 - 7.5e-88 294.9 15.9 9.3e-88 294.6 15.9 1.0 1 0 0 1 1 1 1 Cell cycle protein DUF3624 PF12292.8 KIR62085.1 - 4.3 7.8 5.6 3.6 8.1 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Ala_racemase_N PF01168.20 KIR62086.1 - 5e-19 68.8 4.9 6e-19 68.6 4.9 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-dskA_traR PF01258.17 KIR62087.1 - 2.4e-13 49.8 1.3 4.1e-13 49.0 1.3 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Gluconate_2-dh3 PF13618.6 KIR62087.1 - 0.036 14.3 1.0 0.045 14.0 1.0 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 THDPS_N_2 PF14805.6 KIR62087.1 - 0.074 13.3 0.9 0.29 11.4 0.1 2.1 1 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DZR PF12773.7 KIR62087.1 - 0.081 13.0 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf_C2H2_13 PF18508.1 KIR62087.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Zinc finger domain PEP-utilisers_N PF05524.13 KIR62087.1 - 0.49 10.6 5.3 0.98 9.6 5.3 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal OsmC PF02566.19 KIR62088.1 - 4.4e-19 68.8 0.0 6.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein DUF2470 PF10615.9 KIR62089.1 - 0.0016 19.0 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) PRA-CH PF01502.18 KIR62090.1 - 4.6e-34 116.1 0.4 5.9e-34 115.7 0.4 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase YCII PF03795.14 KIR62092.1 - 2.4e-06 27.8 0.0 3.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain MIase PF02426.16 KIR62092.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 Muconolactone delta-isomerase Uma2 PF05685.12 KIR62093.1 - 1.1e-25 90.2 0.2 1.3e-25 89.9 0.2 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Methyltransf_11 PF08241.12 KIR62094.1 - 2.9e-18 66.3 0.1 5.7e-18 65.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR62094.1 - 1.7e-17 63.9 0.1 3.2e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR62094.1 - 4.4e-12 45.8 0.0 6.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIR62094.1 - 5.8e-09 35.9 0.0 8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62094.1 - 4.7e-07 30.5 0.0 7.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KIR62094.1 - 2e-06 26.7 0.0 2.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 KIR62094.1 - 7.7e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KIR62094.1 - 0.00052 19.6 0.3 0.00072 19.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR62094.1 - 0.03 13.8 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase TPMT PF05724.11 KIR62094.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ABM PF03992.16 KIR62095.1 - 3e-13 49.7 0.2 3.7e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 KIR62095.1 - 0.057 13.7 0.1 0.093 13.0 0.1 1.3 1 1 0 1 1 1 0 NIPSNAP NLPC_P60 PF00877.19 KIR62096.1 - 3.4e-13 49.5 0.0 5.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family SH3_16 PF18348.1 KIR62096.1 - 7.5e-07 28.9 3.1 8.5e-05 22.3 1.0 3.4 2 1 0 2 2 2 2 Bacterial dipeptidyl-peptidase Sh3 domain SNARE_assoc PF09335.11 KIR62097.1 - 8e-14 52.2 5.9 8e-14 52.2 5.9 4.3 3 1 1 4 4 4 2 SNARE associated Golgi protein Crp PF00325.20 KIR62097.1 - 0.021 14.4 3.4 0.43 10.3 0.1 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, crp family HRG PF16954.5 KIR62097.1 - 1.1 9.7 6.7 1.1 9.7 0.1 3.9 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene PAP2 PF01569.21 KIR62097.1 - 9.4 6.0 24.3 0.028 14.2 8.1 3.1 3 0 0 3 3 3 0 PAP2 superfamily Jacalin PF01419.17 KIR62098.1 - 8.7e-09 35.4 0.0 2.2e-08 34.1 0.0 1.6 1 1 1 2 2 2 1 Jacalin-like lectin domain Exo_endo_phos PF03372.23 KIR62098.1 - 1.1e-07 31.7 0.1 6.8e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_31 PF13560.6 KIR62099.1 - 9.7e-12 45.1 7.1 9.5e-11 41.9 1.1 2.8 2 2 1 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 KIR62099.1 - 0.0022 18.0 0.0 0.0072 16.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR62099.1 - 0.015 15.3 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Death PF00531.22 KIR62099.1 - 0.037 14.2 0.1 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 Death domain DUF3071 PF11268.8 KIR62099.1 - 0.091 12.8 0.4 5.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) Acetyltransf_8 PF13523.6 KIR62099.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_23 PF13384.6 KIR62099.1 - 1.9 8.4 5.8 2.7 7.9 0.5 3.1 3 0 0 3 3 3 0 Homeodomain-like domain ATP_bind_2 PF03668.15 KIR62100.1 - 3.4e-103 344.9 0.0 3.8e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 KIR62100.1 - 1.2e-05 25.9 0.2 0.00058 20.4 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR62100.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Glyco_tranf_2_3 PF13641.6 KIR62100.1 - 0.0052 16.7 0.6 0.67 9.8 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 CoaE PF01121.20 KIR62100.1 - 0.065 12.9 0.2 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase SO_alpha_A3 PF17806.1 KIR62100.1 - 0.086 13.2 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain AAA_16 PF13191.6 KIR62100.1 - 0.15 12.4 2.3 0.45 10.9 2.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIR62100.1 - 0.15 12.2 3.8 25 5.0 3.8 3.0 1 1 0 1 1 1 0 AAA domain DUF1884 PF08967.10 KIR62100.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) UPF0052 PF01933.18 KIR62101.1 - 3.3e-62 210.4 0.0 4e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PGI PF00342.19 KIR62102.1 - 1e-07 30.9 0.0 9.2e-07 27.8 0.0 1.9 2 0 0 2 2 2 2 Phosphoglucose isomerase FeS_assembly_P PF01883.19 KIR62104.1 - 1.7e-21 76.2 1.0 2.7e-21 75.5 1.0 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Polysacc_deac_1 PF01522.21 KIR62105.1 - 9.5e-34 116.0 0.0 2.5e-33 114.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase SepZ PF06066.11 KIR62105.1 - 0.17 12.1 4.2 0.17 12.1 1.4 2.3 2 1 0 2 2 2 0 SepZ Zn_peptidase PF04228.13 KIR62106.1 - 5.8e-87 291.8 1.8 7.2e-87 291.5 1.8 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase PSD3 PF07626.11 KIR62106.1 - 0.083 13.4 0.0 4.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) GlgS PF08971.11 KIR62106.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycogen synthesis protein Cad PF03596.13 KIR62107.1 - 4.5e-30 105.0 0.3 1.7e-29 103.1 0.3 1.7 1 1 0 1 1 1 1 Cadmium resistance transporter UDG PF03167.19 KIR62108.1 - 1.4e-24 86.9 0.1 2.4e-24 86.1 0.0 1.4 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF692 PF05114.13 KIR62110.1 - 1e-82 277.3 0.0 1.3e-82 277.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) p450 PF00067.22 KIR62111.1 - 2.9e-64 217.5 0.0 3.8e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.16 KIR62112.1 - 0.00017 21.0 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HisKA PF00512.25 KIR62112.1 - 0.26 11.3 2.3 1 9.4 0.3 2.7 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain GDPD PF03009.17 KIR62113.1 - 5.3e-23 82.1 0.0 6.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Asn_synthase PF00733.21 KIR62115.1 - 8e-98 328.4 0.0 1e-97 328.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KIR62115.1 - 4.1e-40 136.5 0.0 8.2e-40 135.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIR62115.1 - 2.5e-35 121.6 0.0 6.1e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KIR62115.1 - 2.5e-06 27.1 0.0 1.8e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.13 KIR62115.1 - 0.0078 15.7 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC bPH_2 PF03703.14 KIR62116.1 - 1.5e-44 150.0 0.7 1.1e-16 60.8 0.0 3.2 3 0 0 3 3 3 3 Bacterial PH domain TPP_enzyme_N PF02776.18 KIR62118.1 - 2.7e-41 141.1 1.3 6.7e-41 139.7 0.6 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIR62118.1 - 4.6e-26 91.4 0.0 1.3e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIR62118.1 - 2.8e-24 85.4 0.0 9.7e-24 83.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KIR62118.1 - 0.04 13.7 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Acetyltransf_6 PF13480.7 KIR62118.1 - 0.13 12.4 3.5 0.26 11.4 0.8 2.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Inhibitor_I36 PF03995.13 KIR62120.1 - 3.2e-10 39.8 7.6 5.5e-10 39.0 7.6 1.4 1 0 0 1 1 1 1 Peptidase inhibitor family I36 HTH_42 PF06224.12 KIR62121.1 - 1.4e-63 215.5 19.7 1.6e-63 215.3 19.7 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF2382 PF09557.10 KIR62122.1 - 6.2e-26 90.8 19.6 8.4e-26 90.4 19.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2382) PRC PF05239.16 KIR62122.1 - 5.8e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 PRC-barrel domain HipA_C PF07804.12 KIR62123.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 HipA-like C-terminal domain DUF3037 PF11236.8 KIR62124.1 - 2.6e-41 140.8 0.0 2.9e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3037) LtrA PF06772.11 KIR62125.1 - 2.3e-84 283.6 39.7 2.7e-84 283.4 39.7 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) TMEM61 PF15105.6 KIR62125.1 - 0.039 13.8 0.6 0.18 11.6 0.0 2.3 3 0 0 3 3 3 0 TMEM61 protein family Peptidase_M6 PF05547.11 KIR62126.1 - 1.5e-09 36.8 2.6 1.8e-06 26.7 1.5 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 7TMR-DISMED2 PF07696.11 KIR62126.1 - 0.00073 19.6 0.1 0.0037 17.3 0.0 2.1 2 0 0 2 2 2 1 7TMR-DISM extracellular 2 Sulfotransfer_3 PF13469.6 KIR62127.1 - 5.5e-21 75.9 0.7 2.7e-12 47.5 0.2 2.9 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR62127.1 - 1.9e-15 57.1 0.0 3.5e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 KIR62127.1 - 0.039 13.5 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Stf0 sulphotransferase BPD_transp_1 PF00528.22 KIR62128.1 - 3.6e-18 65.9 16.1 3.6e-18 65.9 16.1 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5596 PF18082.1 KIR62128.1 - 0.033 14.0 0.1 1.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) TM_PBP2_N PF16296.5 KIR62128.1 - 0.045 13.9 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters Cation_efflux PF01545.21 KIR62129.1 - 1.4e-13 51.0 10.5 2.6e-12 46.9 10.5 2.0 1 1 0 1 1 1 1 Cation efflux family Aldo_ket_red PF00248.21 KIR62130.1 - 3e-47 161.3 0.0 3.5e-34 118.3 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Hexose_dehydrat PF03559.14 KIR62131.1 - 3.6e-158 522.9 0.0 7.3e-83 277.0 0.0 2.0 2 0 0 2 2 2 2 NDP-hexose 2,3-dehydratase tRNA_int_end_N2 PF12928.7 KIR62131.1 - 0.14 12.3 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term FAD_binding_4 PF01565.23 KIR62132.1 - 1.2e-29 102.8 4.1 2e-29 102.1 4.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIR62132.1 - 4.5e-14 52.3 0.2 7.6e-14 51.5 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like TetR_C_14 PF17754.1 KIR62133.1 - 1.7e-13 50.4 2.3 1.7e-13 50.4 2.3 1.9 2 1 0 2 2 2 1 MftR C-terminal domain TetR_N PF00440.23 KIR62133.1 - 2.4e-11 43.2 1.1 4.3e-11 42.4 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DUF3681 PF12442.8 KIR62133.1 - 0.046 14.2 1.1 0.41 11.1 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) HTH_AraC PF00165.23 KIR62133.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1100 PF06500.11 KIR62134.1 - 5.9e-14 51.7 0.0 8.2e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) FAD_binding_3 PF01494.19 KIR62135.1 - 6.9e-69 232.7 0.0 9e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR62135.1 - 2.8e-15 56.8 4.3 1.6e-07 31.2 0.2 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR62135.1 - 5e-08 32.1 0.3 8.2e-05 21.5 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KIR62135.1 - 1.8e-07 31.6 1.1 0.0012 19.4 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR62135.1 - 4.9e-07 29.3 1.0 0.0076 15.5 0.3 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR62135.1 - 1.1e-06 28.7 1.0 1.3e-05 25.3 0.1 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR62135.1 - 2.7e-05 23.5 6.9 0.003 16.7 0.8 3.2 2 1 1 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 KIR62135.1 - 5.9e-05 22.5 0.0 0.00063 19.1 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIR62135.1 - 0.00053 19.4 4.0 0.006 15.9 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KIR62135.1 - 0.0022 16.9 1.3 0.74 8.6 0.2 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KIR62135.1 - 0.0041 16.2 3.2 0.03 13.4 3.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KIR62135.1 - 0.017 14.4 0.3 0.026 13.7 0.3 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KIR62135.1 - 0.017 14.5 0.1 0.017 14.5 0.1 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KIR62135.1 - 0.034 14.4 0.3 0.64 10.3 0.1 2.6 3 0 0 3 3 3 0 TrkA-N domain ApbA PF02558.16 KIR62135.1 - 0.053 13.2 0.2 0.094 12.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 KIR62135.1 - 0.11 11.7 0.1 1.1 8.3 0.1 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_14 PF08484.11 KIR62136.1 - 1.8e-54 183.9 0.0 2.4e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 KIR62136.1 - 5.3e-20 71.4 0.5 1e-19 70.5 0.5 1.5 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 KIR62136.1 - 8e-19 68.1 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62136.1 - 3.1e-10 40.7 0.0 5.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR62136.1 - 1.2e-07 32.3 0.0 2.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR62136.1 - 9.7e-07 29.4 0.0 3.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR62136.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIR62136.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 KIR62137.1 - 4.3e-17 62.6 0.1 8.4e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR62137.1 - 1.1e-16 61.2 0.1 2.7e-16 60.0 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR62137.1 - 2e-16 60.2 0.0 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62137.1 - 1.1e-13 51.7 0.2 8.9e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR62137.1 - 1.4e-13 51.0 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR62137.1 - 5.1e-08 32.5 0.0 7.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.8 KIR62137.1 - 6.3e-06 25.6 0.0 8.7e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 KIR62137.1 - 0.00016 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 KIR62137.1 - 0.00036 20.1 0.0 0.094 12.2 0.0 2.2 1 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_15 PF09445.10 KIR62137.1 - 0.00064 19.3 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 KIR62137.1 - 0.0019 19.2 0.0 0.0034 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR62137.1 - 0.0042 16.6 0.0 0.01 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 KIR62137.1 - 0.0074 16.3 0.1 0.045 13.7 0.1 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NodS PF05401.11 KIR62137.1 - 0.0099 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) SAM_MT PF04445.13 KIR62137.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase MetW PF07021.12 KIR62137.1 - 0.032 13.8 0.1 0.067 12.8 0.1 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 KIR62137.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 1 0 1 1 1 0 DREV methyltransferase Flavin_Reduct PF01613.18 KIR62138.1 - 2.4e-37 128.4 0.0 2.7e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain UDPGT PF00201.18 KIR62139.1 - 3.8e-12 45.8 0.0 4.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIR62139.1 - 3.3e-09 36.9 0.0 3.8e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KIR62139.1 - 0.0038 16.5 0.0 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 B12-binding PF02310.19 KIR62141.1 - 5.8e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain SKI PF01202.22 KIR62145.1 - 4.2e-39 134.2 0.0 4.7e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KIR62145.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIR62145.1 - 8.8e-05 23.1 0.0 0.00012 22.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIR62145.1 - 0.00019 21.9 0.0 0.0003 21.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KIR62145.1 - 0.00047 20.3 0.0 0.00057 20.1 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_5 PF07728.14 KIR62145.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIR62145.1 - 0.002 18.4 0.0 0.0036 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR62145.1 - 0.0026 18.0 0.3 0.0072 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIR62145.1 - 0.0029 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KIR62145.1 - 0.004 16.9 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR62145.1 - 0.0067 16.8 0.5 0.011 16.2 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KIR62145.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 KIR62145.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 KIR62145.1 - 0.015 15.7 0.6 0.018 15.4 0.6 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIR62145.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 KIR62145.1 - 0.029 14.0 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIR62145.1 - 0.029 14.1 1.2 0.057 13.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain CoaE PF01121.20 KIR62145.1 - 0.081 12.6 0.2 0.14 11.8 0.1 1.6 1 1 1 2 2 2 0 Dephospho-CoA kinase AAA_21 PF13304.6 KIR62145.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KIR62145.1 - 0.087 13.2 0.0 0.2 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIR62145.1 - 0.097 13.2 0.1 0.12 12.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KIR62145.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_3 PF07726.11 KIR62145.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIR62145.1 - 0.2 12.1 0.0 0.26 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain PriA_3primeBD PF17764.1 KIR62146.1 - 2.3e-16 59.4 0.0 4.8e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) TF_Zn_Ribbon PF08271.12 KIR62146.1 - 0.14 11.7 0.2 9.8 5.8 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding PSK_trans_fac PF07704.11 KIR62146.1 - 0.17 12.6 2.8 0.5 11.2 0.0 3.0 3 0 0 3 3 3 0 Rv0623-like transcription factor Zn_ribbon_SprT PF17283.2 KIR62146.1 - 0.65 10.0 5.4 4.6 7.2 0.2 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Anti-TRAP PF15777.5 KIR62146.1 - 2 8.4 10.9 2.9 7.9 1.7 2.8 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1272 PF06906.11 KIR62146.1 - 4.1 7.6 8.1 14 5.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Septum_form PF13845.6 KIR62147.1 - 1.7e-52 178.2 0.3 1.9e-52 178.0 0.3 1.0 1 0 0 1 1 1 1 Septum formation cNMP_binding PF00027.29 KIR62148.1 - 4.1e-16 58.8 0.0 6.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 KIR62148.1 - 7.7e-14 51.4 1.8 1.5e-13 50.5 1.8 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KIR62148.1 - 1.4e-05 24.9 1.0 4.9e-05 23.1 1.0 2.1 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR62148.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 KIR62148.1 - 0.055 13.1 0.1 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.19 KIR62148.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 KIR62148.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain FCD PF07729.12 KIR62149.1 - 0.21 12.0 1.6 1.2 9.6 1.6 2.0 1 1 0 1 1 1 0 FCD domain HSP20 PF00011.21 KIR62150.1 - 7.4e-15 54.9 0.0 9.1e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIR62150.1 - 1.2e-10 40.8 0.0 2.2e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Radical_SAM PF04055.21 KIR62151.1 - 9e-27 94.5 0.0 1.3e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KIR62151.1 - 1.8e-14 54.2 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIR62151.1 - 8.9e-09 35.5 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain PFL-like PF02901.15 KIR62152.1 - 6.6e-188 626.4 0.0 9e-188 625.9 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 KIR62152.1 - 3.9e-40 136.7 0.0 7.1e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 Glycine radical DUF3029 PF11230.8 KIR62152.1 - 0.13 10.6 0.0 0.38 9.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3029) Acetyltransf_3 PF13302.7 KIR62153.1 - 8.9e-20 71.8 0.0 1.1e-19 71.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR62153.1 - 3.3e-08 33.8 0.0 4.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family tRNA-synt_1b PF00579.25 KIR62154.1 - 9.3e-75 251.7 0.0 1.2e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KIR62154.1 - 2.1e-05 24.3 0.1 0.0031 17.3 0.1 2.3 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 KIR62154.1 - 0.00028 20.5 0.0 0.00081 19.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain NAD_kinase PF01513.21 KIR62155.1 - 1.3e-56 192.0 0.0 1.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KIR62155.1 - 0.0093 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TPPK_C PF12555.8 KIR62156.1 - 3e-16 59.2 5.0 3e-16 59.2 5.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphokinase C terminal TPK_catalytic PF04263.16 KIR62156.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Glycos_transf_4 PF00953.21 KIR62157.1 - 0.003 17.5 0.6 0.018 15.0 0.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 4 Glycos_transf_1 PF00534.20 KIR62158.1 - 8.3e-26 90.5 0.0 1.2e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR62158.1 - 3.8e-24 85.6 0.2 8.4e-24 84.5 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR62158.1 - 2.6e-22 80.0 24.7 2.6e-22 80.0 24.7 3.4 1 1 2 3 3 3 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR62158.1 - 1.7e-13 51.0 5.4 1.7e-13 51.0 5.4 2.5 1 1 1 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIR62158.1 - 1.6e-05 25.2 0.1 4.2e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIR62158.1 - 0.00072 19.3 2.8 0.6 9.8 0.1 2.2 1 1 1 2 2 2 2 Starch synthase catalytic domain Phosphodiest PF01663.22 KIR62159.1 - 0.076 12.6 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Phage_integrase PF00589.22 KIR62160.1 - 1.7e-40 138.6 0.0 2.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KIR62160.1 - 4.5e-20 71.7 0.3 1.5e-19 70.0 0.1 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain DDE_Tnp_4 PF13359.6 KIR62161.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR62161.1 - 4.7e-15 55.0 0.0 9.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR62161.1 - 3.7e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR62161.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_38 PF13936.6 KIR62161.1 - 0.06 13.1 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIR62161.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DUF4041 PF13250.6 KIR62162.1 - 3.2e-19 68.5 0.0 1e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4041) T5orf172 PF10544.9 KIR62162.1 - 8.4e-13 48.8 1.5 4.8e-12 46.3 0.0 2.7 3 0 0 3 3 3 1 T5orf172 domain MUG113 PF13455.6 KIR62162.1 - 4.5e-11 43.3 3.1 4.8e-11 43.2 0.0 2.5 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 DUF3618 PF12277.8 KIR62162.1 - 0.031 14.5 17.5 1.9 8.8 0.6 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) ExsD PF16806.5 KIR62162.1 - 0.043 13.7 2.4 0.89 9.4 0.5 2.3 2 0 0 2 2 2 0 Antiactivator protein ExsD OmpH PF03938.14 KIR62162.1 - 0.06 13.7 20.3 0.34 11.2 6.7 3.1 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) LegC3_N PF18654.1 KIR62162.1 - 0.38 10.0 13.2 0.4 9.9 7.8 2.2 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Atg14 PF10186.9 KIR62162.1 - 0.67 9.0 7.7 1.7 7.6 1.9 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1690 PF07956.11 KIR62162.1 - 0.97 9.9 14.2 0.092 13.2 7.4 2.5 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Herpes_UL17 PF04559.12 KIR62162.1 - 1 8.0 7.4 0.21 10.4 3.0 1.8 2 0 0 2 2 2 0 Herpesvirus UL17 protein TMCO5 PF14992.6 KIR62162.1 - 1.8 8.1 10.1 0.22 11.1 5.1 1.8 2 0 0 2 2 2 0 TMCO5 family TMPIT PF07851.13 KIR62162.1 - 2.4 7.3 4.5 1.1 8.4 2.0 1.7 2 0 0 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 KIR62162.1 - 3.2 7.5 10.8 1.8 8.3 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DDE_Tnp_4 PF13359.6 KIR62164.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR62164.1 - 4.7e-15 55.0 0.0 9.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR62164.1 - 3.7e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR62164.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_38 PF13936.6 KIR62164.1 - 0.06 13.1 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIR62164.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DUF1998 PF09369.10 KIR62165.1 - 6.5e-05 23.6 1.2 0.00016 22.4 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DDE_Tnp_4 PF13359.6 KIR62166.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR62166.1 - 4.7e-15 55.0 0.0 9.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR62166.1 - 3.7e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR62166.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_38 PF13936.6 KIR62166.1 - 0.06 13.1 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIR62166.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MLTR_LBD PF17765.1 KIR62167.1 - 5.5e-40 137.2 9.5 5.5e-40 137.2 9.5 1.9 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KIR62167.1 - 9.5e-16 57.9 5.6 2.1e-15 56.8 5.6 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62167.1 - 4.1e-07 29.9 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix PAS_8 PF13188.7 KIR62167.1 - 0.035 14.2 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 KIR62167.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 1 1 0 1 1 1 0 PAS fold DUF998 PF06197.13 KIR62168.1 - 1.4e-16 60.7 24.9 1.6e-16 60.4 24.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Frag1 PF10277.9 KIR62168.1 - 0.026 14.1 0.2 0.036 13.6 0.2 1.4 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family RicinB_lectin_2 PF14200.6 KIR62169.1 - 2e-35 121.4 19.4 2.6e-20 72.9 7.4 3.1 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR62169.1 - 2.2e-13 50.6 5.2 4.8e-13 49.5 5.2 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Esterase PF00756.20 KIR62169.1 - 0.00087 19.0 0.7 0.0077 15.9 0.5 2.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KIR62169.1 - 0.013 15.0 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIR62169.1 - 0.019 14.6 0.6 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Rhomboid_SP PF12595.8 KIR62169.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Rhomboid serine protease PAS_7 PF12860.7 KIR62169.1 - 0.05 13.8 0.0 3.2 7.9 0.0 2.5 1 1 1 2 2 2 0 PAS fold Peripla_BP_3 PF13377.6 KIR62170.1 - 5.7e-29 101.6 0.3 4.8e-28 98.6 0.4 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR62170.1 - 7.8e-16 57.6 0.0 2e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 KIR62170.1 - 4.4e-09 36.2 0.0 5.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR62170.1 - 1.6e-05 24.6 0.0 0.00024 20.8 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_3 PF01381.22 KIR62170.1 - 3.8e-05 23.6 0.0 8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR62170.1 - 0.00015 22.1 2.6 0.001 19.4 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR62170.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Molybdopterin_N PF18364.1 KIR62170.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain HTH_23 PF13384.6 KIR62170.1 - 0.15 11.9 2.9 0.25 11.2 0.0 2.9 4 0 0 4 4 4 0 Homeodomain-like domain HTH_26 PF13443.6 KIR62170.1 - 0.19 12.2 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Cupin_2 PF07883.11 KIR62171.1 - 1e-07 31.6 0.5 2.2e-07 30.5 0.5 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KIR62171.1 - 0.00012 21.7 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 Cupin 2-Hacid_dh_C PF02826.19 KIR62172.1 - 6.2e-46 156.0 0.0 8.6e-46 155.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIR62172.1 - 1.2e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain BPD_transp_1 PF00528.22 KIR62173.1 - 6.6e-16 58.6 14.4 6.6e-16 58.6 14.4 1.6 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Glyco_hydro_43 PF04616.14 KIR62174.1 - 3.5e-22 79.1 0.0 6.3e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 KIR62175.1 - 3.1e-92 308.9 0.0 4.3e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIR62175.1 - 7.1e-36 123.8 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain BPD_transp_1 PF00528.22 KIR62176.1 - 6.7e-19 68.3 14.9 6.7e-19 68.3 14.9 2.4 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3566 PF12089.8 KIR62176.1 - 0.022 15.1 1.6 0.022 15.1 1.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Col_cuticle_N PF01484.17 KIR62176.1 - 0.23 11.6 7.8 0.6 10.2 1.9 2.9 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Glycophorin_A PF01102.18 KIR62176.1 - 2.1 8.6 3.4 4.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A DDE_Tnp_4 PF13359.6 KIR62177.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR62177.1 - 4.7e-15 55.0 0.0 9.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR62177.1 - 3.7e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR62177.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_38 PF13936.6 KIR62177.1 - 0.06 13.1 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIR62177.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MerR_1 PF13411.6 KIR62178.1 - 5.9e-18 64.7 0.5 8.5e-18 64.2 0.1 1.4 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 KIR62178.1 - 1e-14 54.0 5.3 1.5e-14 53.5 3.2 2.1 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KIR62178.1 - 1.1e-06 29.1 1.3 1.6e-06 28.5 1.3 1.3 1 0 0 1 1 1 1 MerR, DNA binding HTH_17 PF12728.7 KIR62178.1 - 0.032 14.4 0.3 0.2 11.8 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain AbiEi_4 PF13338.6 KIR62178.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.6 4 1 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin BPD_transp_1 PF00528.22 KIR62179.1 - 5e-22 78.5 12.2 5e-22 78.5 12.2 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component F5_F8_type_C PF00754.25 KIR62180.1 - 3.1e-12 46.7 11.0 1.3e-08 35.1 6.3 2.8 2 0 0 2 2 2 2 F5/8 type C domain Big_4 PF07532.11 KIR62180.1 - 2e-11 43.5 9.8 1.3e-07 31.2 0.0 4.8 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 4) Glyco_hydro_43 PF04616.14 KIR62181.1 - 4.1e-48 164.2 0.2 7.3e-48 163.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RicinB_lectin_2 PF14200.6 KIR62181.1 - 8.2e-26 90.6 10.2 1.6e-18 67.2 0.6 3.9 2 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR62181.1 - 8.9e-09 35.7 0.4 1.6e-08 34.9 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain BPD_transp_1 PF00528.22 KIR62182.1 - 1.8e-18 66.9 14.3 1.8e-18 66.9 14.3 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR62183.1 - 7.1e-18 65.0 13.6 7.1e-18 65.0 13.6 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4064 PF13273.6 KIR62183.1 - 0.057 13.7 0.3 0.057 13.7 0.3 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) F5_F8_type_C PF00754.25 KIR62184.1 - 3.1e-33 114.6 8.1 1.4e-17 64.0 0.2 3.4 3 0 0 3 3 3 2 F5/8 type C domain Pectate_lyase_3 PF12708.7 KIR62184.1 - 9.3e-15 55.1 14.7 2.9e-14 53.4 6.0 2.9 1 1 1 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.6 KIR62184.1 - 2.5e-05 24.2 7.6 2.5e-05 24.2 7.6 3.3 2 1 1 3 3 3 2 Right handed beta helix region DUF5000 PF16391.5 KIR62184.1 - 0.00017 21.7 0.0 2.8 8.0 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function Response_reg PF00072.24 KIR62185.1 - 5.8e-35 119.9 0.0 7.9e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR62185.1 - 2.7e-27 94.7 0.0 8.1e-27 93.1 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 KIR62185.1 - 0.0014 18.5 0.8 0.03 14.2 0.5 3.1 2 1 0 2 2 2 1 MarR family B12-binding PF02310.19 KIR62185.1 - 0.0038 17.3 0.0 0.0086 16.1 0.0 1.6 2 0 0 2 2 2 1 B12 binding domain OKR_DC_1_N PF03709.15 KIR62185.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PKD PF00801.20 KIR62185.1 - 0.19 11.6 0.2 1.8 8.5 0.3 2.1 2 0 0 2 2 2 0 PKD domain Oxidored_molyb PF00174.19 KIR62186.1 - 4e-24 85.1 0.0 5.9e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain DUF4405 PF14358.6 KIR62186.1 - 0.096 13.2 13.8 1.6 9.3 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DUF2064 PF09837.9 KIR62187.1 - 2e-24 85.7 1.3 3.8e-24 84.8 1.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) BPD_transp_1 PF00528.22 KIR62188.1 - 2.7e-32 112.0 10.4 2.7e-32 112.0 10.4 1.4 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF805 PF05656.14 KIR62188.1 - 1.3 9.5 6.1 0.23 11.9 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF805) LUD_dom PF02589.15 KIR62189.1 - 3.7e-46 157.2 0.1 6.7e-46 156.4 0.1 1.4 1 0 0 1 1 1 1 LUD domain Fer4_8 PF13183.6 KIR62189.1 - 2.1e-08 34.5 3.8 6.9e-07 29.6 4.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain DUF3390 PF11870.8 KIR62189.1 - 8.1e-07 29.3 4.5 1.8e-06 28.2 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4 PF00037.27 KIR62189.1 - 3.4e-05 23.5 12.1 0.012 15.4 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KIR62189.1 - 4.6e-05 23.4 7.6 0.0012 18.9 8.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR62189.1 - 5.4e-05 23.7 5.8 0.00021 21.8 5.8 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KIR62189.1 - 0.00011 22.7 3.0 0.00098 19.6 3.5 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR62189.1 - 0.00057 19.8 10.0 0.058 13.5 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KIR62189.1 - 0.00068 20.4 12.5 0.2 12.7 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KIR62189.1 - 0.0012 19.0 7.0 0.029 14.5 8.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_20 PF14691.6 KIR62189.1 - 0.0012 18.6 2.3 0.62 9.8 0.0 2.3 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_18 PF13746.6 KIR62189.1 - 0.0015 18.7 2.1 0.6 10.3 0.2 2.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIR62189.1 - 0.0016 18.4 13.2 0.01 15.9 3.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIR62189.1 - 0.0021 18.4 7.6 0.19 12.3 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KIR62189.1 - 0.0071 16.5 4.6 0.093 12.9 0.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR62189.1 - 0.026 15.5 10.0 0.53 11.3 10.3 2.3 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Gloverin PF10793.9 KIR62189.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Gloverin-like protein Fer4_13 PF13370.6 KIR62189.1 - 1.5 9.4 6.5 9.9 6.8 6.5 2.1 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I LUD_dom PF02589.15 KIR62190.1 - 1.8e-23 83.3 0.0 3.6e-22 79.0 0.0 2.0 2 0 0 2 2 2 2 LUD domain AMP-binding PF00501.28 KIR62191.1 - 1.4e-98 330.3 0.1 1.7e-98 330.0 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR62191.1 - 1.3e-25 90.2 0.5 2.7e-25 89.2 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Prot_ATP_ID_OB PF16450.5 KIR62191.1 - 0.0025 17.7 0.0 0.0087 16.0 0.0 2.0 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain TetR_C_24 PF17932.1 KIR62192.1 - 7.1e-33 113.3 0.6 1.1e-32 112.6 0.6 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR62192.1 - 1.4e-12 47.2 0.1 2.2e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 KIR62192.1 - 0.034 14.2 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 KIR62192.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region UPF0261 PF06792.11 KIR62194.1 - 7e-155 515.9 1.6 7.8e-155 515.8 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) DrsE PF02635.15 KIR62194.1 - 0.067 13.6 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 DsrE/DsrF-like family PepSY_2 PF13670.6 KIR62194.1 - 0.73 9.9 7.9 37 4.4 3.6 3.9 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain GHMP_kinases_C PF08544.13 KIR62194.1 - 4.2 7.8 8.0 1.2 9.5 0.1 2.9 2 0 0 2 2 2 0 GHMP kinases C terminal adh_short_C2 PF13561.6 KIR62195.1 - 2.6e-53 181.0 3.1 3.1e-53 180.8 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR62195.1 - 2.8e-48 164.0 0.3 3.3e-48 163.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR62195.1 - 3e-08 33.8 3.5 5.8e-08 32.8 3.3 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KIR62195.1 - 8.5e-05 22.1 1.0 0.00016 21.2 1.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR62195.1 - 0.043 12.9 0.7 0.074 12.1 0.7 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIR62195.1 - 0.057 12.4 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 KIR62195.1 - 0.092 12.6 1.4 0.21 11.5 0.8 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBP_bac_1 PF01547.25 KIR62196.1 - 5.7e-29 102.1 12.7 5.7e-29 102.1 12.7 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR62196.1 - 4.7e-23 82.4 7.2 6.8e-23 81.9 7.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Sigma70_r2 PF04542.14 KIR62197.1 - 3.2e-17 62.1 0.3 7.1e-17 60.9 0.3 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR62197.1 - 4e-14 51.9 0.2 1.1e-13 50.4 0.2 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIR62197.1 - 3.2e-11 42.7 0.3 7.5e-11 41.5 0.3 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR62197.1 - 5e-05 23.3 1.9 9.1e-05 22.4 1.9 1.6 1 1 0 1 1 1 1 ECF sigma factor DUF742 PF05331.11 KIR62197.1 - 0.00033 20.4 0.3 0.00083 19.1 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF742) MarR_2 PF12802.7 KIR62197.1 - 0.00035 20.4 2.9 0.00062 19.6 0.1 2.7 2 1 1 3 3 3 1 MarR family DprA_WH PF17782.1 KIR62197.1 - 0.00038 20.5 0.4 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 DprA winged helix domain HTH_28 PF13518.6 KIR62197.1 - 0.0063 16.6 1.2 0.15 12.2 0.0 3.1 3 1 0 3 3 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KIR62197.1 - 0.022 14.3 0.0 0.078 12.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r3 PF04539.16 KIR62197.1 - 0.033 14.3 0.1 0.15 12.2 0.0 2.2 1 1 0 2 2 2 0 Sigma-70 region 3 HTH_23 PF13384.6 KIR62197.1 - 0.043 13.6 0.3 0.043 13.6 0.3 2.2 2 1 0 2 2 2 0 Homeodomain-like domain MscS_TM PF12794.7 KIR62197.1 - 0.085 11.7 2.0 0.13 11.1 2.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HTH_5 PF01022.20 KIR62197.1 - 0.18 11.7 0.0 0.44 10.5 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family LUD_dom PF02589.15 KIR62198.1 - 3.4e-23 82.3 0.1 4.9e-21 75.3 0.1 2.1 1 1 1 2 2 2 2 LUD domain ABC_tran_2 PF16949.5 KIR62198.1 - 0.2 10.5 0.0 0.24 10.2 0.0 1.0 1 0 0 1 1 1 0 Putative ATP-binding cassette Glyco_hydro_43 PF04616.14 KIR62199.1 - 5e-80 268.9 0.0 6.6e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIR62199.1 - 7.1e-27 94.4 0.0 5e-26 91.7 0.0 1.9 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Reg_prop PF07494.11 KIR62199.1 - 0.092 13.0 1.7 13 6.5 0.1 3.4 3 0 0 3 3 3 0 Two component regulator propeller DUF2083 PF09856.9 KIR62200.1 - 2.5e-67 225.6 0.0 4.6e-67 224.7 0.0 1.4 1 0 0 1 1 1 1 Predicted transcriptional regulator (DUF2083) Peptidase_M78 PF06114.13 KIR62200.1 - 2.9e-19 69.2 0.9 7.1e-19 67.9 0.9 1.7 1 0 0 1 1 1 1 IrrE N-terminal-like domain HTH_31 PF13560.6 KIR62200.1 - 1.6e-11 44.4 0.0 1.6e-11 44.4 0.0 3.7 3 1 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62200.1 - 5.9e-11 42.2 0.0 7.9e-10 38.6 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix HTH_19 PF12844.7 KIR62200.1 - 2.1e-09 37.2 0.0 5.8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR62200.1 - 7.2e-06 25.8 0.6 3e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR62200.1 - 0.00014 22.2 0.0 0.00044 20.6 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 KIR62200.1 - 0.0029 17.5 0.0 0.0083 16.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR62200.1 - 0.079 12.5 0.8 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 KIR62200.1 - 0.16 11.6 0.1 0.4 10.3 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding YdaS_antitoxin PF15943.5 KIR62200.1 - 0.17 11.8 0.0 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Aminotran_5 PF00266.19 KIR62201.1 - 3.1e-45 154.7 0.0 3.5e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Peripla_BP_1 PF00532.21 KIR62201.1 - 0.018 14.5 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family FCD PF07729.12 KIR62202.1 - 1.2e-24 87.1 11.0 2.5e-24 86.1 11.0 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KIR62202.1 - 4e-19 68.0 0.2 4e-19 68.0 0.2 2.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 KIR62202.1 - 5.2e-05 23.1 0.2 0.00015 21.7 0.0 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KIR62202.1 - 0.00014 21.3 0.1 0.00055 19.4 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR62202.1 - 0.0015 18.3 0.3 0.0074 16.2 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 KIR62202.1 - 0.0026 17.6 0.0 0.0085 16.0 0.0 1.9 1 0 0 1 1 1 1 HTH domain FaeA PF04703.12 KIR62202.1 - 0.0028 18.0 0.1 0.059 13.7 0.0 2.3 1 1 1 2 2 2 1 FaeA-like protein TrmB PF01978.19 KIR62202.1 - 0.0039 17.0 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 KIR62202.1 - 0.0041 17.0 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 KIR62202.1 - 0.015 15.1 1.4 0.11 12.4 0.0 2.9 3 1 0 3 3 3 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 KIR62202.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 KIR62202.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator HTH_29 PF13551.6 KIR62202.1 - 0.031 14.3 0.0 0.65 10.1 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn helix DUF505 PF04458.12 KIR62202.1 - 0.033 12.6 0.1 0.055 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF505) HTH_28 PF13518.6 KIR62202.1 - 0.053 13.7 6.8 0.15 12.2 0.0 3.4 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_CodY PF08222.11 KIR62202.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_36 PF13730.6 KIR62202.1 - 0.072 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain FSIP2 PF15783.5 KIR62202.1 - 0.072 11.0 0.0 0.095 10.6 0.0 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 ABATE PF07336.11 KIR62202.1 - 9.1 7.0 12.4 2.4 8.8 7.7 2.3 1 1 1 2 2 2 0 Putative stress-induced transcription regulator Gln-synt_C PF00120.24 KIR62203.1 - 4.7e-78 262.6 0.0 5.7e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KIR62203.1 - 1.9e-09 37.3 0.1 1.1e-08 34.8 0.1 2.2 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 KIR62203.1 - 0.00017 21.2 0.0 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Amidase PF01425.21 KIR62204.1 - 8e-83 278.9 5.4 1.9e-82 277.6 5.4 1.5 1 1 0 1 1 1 1 Amidase DUF3693 PF12472.8 KIR62204.1 - 0.1 12.3 0.0 0.49 10.1 0.0 2.2 1 0 0 1 1 1 0 Phage related protein Peripla_BP_2 PF01497.18 KIR62205.1 - 4.2e-34 118.2 0.0 5.6e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 KIR62206.1 - 1.5e-25 90.3 0.0 2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR62206.1 - 2.7e-08 34.0 0.1 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR62206.1 - 1.5e-07 31.1 0.0 0.0036 16.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR62206.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 KIR62206.1 - 0.00091 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KIR62206.1 - 0.0027 16.6 0.4 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 KIR62206.1 - 0.0069 16.0 1.1 0.017 14.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR62206.1 - 0.0076 16.8 0.0 0.01 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR62206.1 - 0.013 15.7 0.2 0.08 13.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR62206.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KIR62206.1 - 0.041 14.1 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR62206.1 - 0.11 12.2 4.6 0.33 10.7 4.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR62206.1 - 0.13 12.6 3.8 0.59 10.5 3.8 1.9 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KIR62206.1 - 0.15 11.7 0.1 2.8 7.5 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KIR62206.1 - 0.16 12.1 0.1 0.51 10.4 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF2470 PF10615.9 KIR62207.1 - 3.9e-19 69.1 0.0 5.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) HTH_23 PF13384.6 KIR62207.1 - 0.091 12.6 0.1 0.42 10.5 0.1 2.1 1 1 0 1 1 1 0 Homeodomain-like domain ABC_tran PF00005.27 KIR62208.1 - 9.3e-32 110.4 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR62208.1 - 3.3e-06 27.6 0.0 4.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIR62208.1 - 1.6e-05 24.9 0.2 0.0042 16.9 0.2 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KIR62208.1 - 0.0003 21.1 0.0 0.00064 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR62208.1 - 0.0004 20.7 0.1 0.0011 19.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KIR62208.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KIR62208.1 - 0.0017 18.8 0.1 0.0043 17.5 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIR62208.1 - 0.0064 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KIR62208.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIR62208.1 - 0.021 14.4 0.0 0.054 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF5632 PF18646.1 KIR62208.1 - 0.022 14.8 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5632) ATPase_2 PF01637.18 KIR62208.1 - 0.029 14.3 0.0 0.061 13.2 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KIR62208.1 - 0.029 14.0 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KIR62208.1 - 0.03 14.1 0.1 0.081 12.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KIR62208.1 - 0.036 12.9 0.1 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 KIR62208.1 - 0.037 14.2 0.4 0.059 13.5 0.4 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIR62208.1 - 0.046 13.8 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 KIR62208.1 - 0.046 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 KIR62208.1 - 0.054 12.7 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.12 KIR62208.1 - 0.058 13.3 0.1 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KIR62208.1 - 0.061 13.9 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIR62208.1 - 0.071 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 KIR62208.1 - 0.082 12.6 0.1 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.9 KIR62208.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 KIR62208.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 KIR62208.1 - 0.18 11.7 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 KIR62208.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 KIR62208.1 - 0.2 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 KIR62208.1 - 0.21 11.7 0.1 0.63 10.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIR62208.1 - 0.21 10.9 0.1 3.8 6.8 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 KIR62208.1 - 0.24 11.9 0.1 0.34 11.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIR62208.1 - 0.25 11.8 0.1 0.44 11.0 0.1 1.4 1 0 0 1 1 1 0 RNA helicase dNK PF01712.19 KIR62208.1 - 0.34 10.8 0.3 0.52 10.1 0.3 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Glyco_hydro_3 PF00933.21 KIR62209.1 - 7.3e-67 226.0 0.0 9.3e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIR62209.1 - 1e-42 146.4 0.0 1.5e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIR62209.1 - 7.3e-19 67.7 0.2 1.9e-18 66.3 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 KIR62209.1 - 0.016 15.5 0.4 0.058 13.7 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 BPD_transp_1 PF00528.22 KIR62210.1 - 3.8e-17 62.6 12.7 5.6e-17 62.1 12.7 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR62211.1 - 7.8e-17 61.6 12.2 7.8e-17 61.6 12.2 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 KIR62212.1 - 7.3e-35 121.1 13.7 9.8e-35 120.7 13.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR62212.1 - 1.6e-30 107.1 16.3 2.7e-30 106.4 16.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Peripla_BP_3 PF13377.6 KIR62213.1 - 6.4e-37 127.4 0.2 9.9e-37 126.8 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR62213.1 - 3.8e-15 56.1 0.0 4.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR62213.1 - 3.4e-14 52.4 0.0 8.3e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR62213.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR62213.1 - 0.0045 17.3 4.3 0.0074 16.6 1.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain TetR_N PF00440.23 KIR62213.1 - 0.015 15.0 0.1 0.054 13.3 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family CcmH PF03918.14 KIR62214.1 - 0.074 12.3 0.3 0.074 12.3 0.3 2.3 3 0 0 3 3 3 0 Cytochrome C biogenesis protein SHMT PF00464.19 KIR62215.1 - 2.4e-128 428.2 0.0 2.8e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HisKA_3 PF07730.13 KIR62216.1 - 2.7e-09 37.4 7.5 1.1e-08 35.4 7.5 2.1 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 KIR62216.1 - 2.3e-07 31.3 0.0 1.6e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR62216.1 - 3.2e-06 27.1 0.0 7.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain BTAD PF03704.17 KIR62217.1 - 1.8e-15 57.7 4.0 2.8e-15 57.0 4.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KIR62217.1 - 2.1e-09 37.3 0.0 9e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal TPR_14 PF13428.6 KIR62217.1 - 0.0017 19.0 3.5 4.4 8.4 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat NT5C PF06941.12 KIR62217.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF4131 PF13567.6 KIR62218.1 - 0.0024 17.5 5.3 0.0025 17.5 5.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) UPF0114 PF03350.16 KIR62218.1 - 0.041 14.1 1.4 0.041 14.1 1.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein family, UPF0114 DUF4231 PF14015.6 KIR62218.1 - 0.064 13.7 2.8 0.066 13.7 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 KIR62218.1 - 0.16 10.7 4.8 0.16 10.7 4.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4175 PF13779.6 KIR62218.1 - 0.17 9.8 5.7 0.16 9.9 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FixQ PF05545.11 KIR62218.1 - 0.25 11.4 0.3 0.25 11.4 0.3 1.9 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PrgI PF12666.7 KIR62218.1 - 0.53 11.0 4.2 0.56 10.9 4.2 1.1 1 0 0 1 1 1 0 PrgI family protein FA_desaturase PF00487.24 KIR62218.1 - 0.56 10.0 4.6 0.56 10.0 4.6 1.0 1 0 0 1 1 1 0 Fatty acid desaturase DUF3784 PF12650.7 KIR62218.1 - 0.68 10.2 6.3 0.78 10.0 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF3742 PF12553.8 KIR62218.1 - 0.85 9.7 4.4 0.84 9.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Zn_peptidase_2 PF04298.12 KIR62218.1 - 0.95 8.8 6.2 1.2 8.6 6.2 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Wzy_C PF04932.15 KIR62218.1 - 1.1 8.9 5.9 1.2 8.7 5.9 1.0 1 0 0 1 1 1 0 O-Antigen ligase DUF4191 PF13829.6 KIR62218.1 - 1.9 7.8 7.3 2 7.7 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Pox_A14 PF05767.12 KIR62218.1 - 5.5 7.2 9.4 1.1 9.5 2.3 2.0 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 PhoR PF11808.8 KIR62218.1 - 6.8 7.2 13.5 3 8.3 11.8 1.3 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR Acetyltransf_4 PF13420.7 KIR62219.1 - 2.2e-13 50.6 0.0 2.6e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR62219.1 - 2.9e-11 43.6 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR62219.1 - 1.9e-07 31.4 0.0 2.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR62219.1 - 5.9e-06 27.0 0.0 6.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR62219.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR62219.1 - 0.00036 20.5 0.0 0.0015 18.5 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KIR62219.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KIR62219.1 - 0.046 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Adeno_E4 PF05385.11 KIR62219.1 - 0.064 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein GNAT_acetyltran PF12746.7 KIR62219.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Lant_dehydr_N PF04738.13 KIR62221.1 - 5.2e-38 130.6 19.2 2e-27 95.6 14.5 2.1 1 1 1 2 2 2 2 Lantibiotic dehydratase, N terminus Lant_dehydr_N PF04738.13 KIR62222.1 - 8.4e-39 133.2 16.8 3.5e-28 98.1 12.7 2.5 2 1 0 2 2 2 2 Lantibiotic dehydratase, N terminus ketoacyl-synt PF00109.26 KIR62223.1 - 1.4e-72 244.3 0.0 1.4e-72 244.3 0.0 2.8 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR62223.1 - 1e-58 199.4 0.9 2e-58 198.4 0.9 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIR62223.1 - 6.2e-45 153.3 0.3 1.3e-44 152.3 0.3 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KIR62223.1 - 4.6e-44 150.8 6.8 9.4e-44 149.8 6.8 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KIR62223.1 - 2.3e-39 134.1 0.3 7.1e-39 132.5 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR62223.1 - 3.3e-18 66.2 0.0 6.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR62223.1 - 2.5e-15 56.6 0.0 7.6e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KIR62223.1 - 7.2e-11 41.9 0.3 1.2e-08 34.6 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIR62223.1 - 8.4e-10 38.6 0.1 2.9e-09 36.8 0.1 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KIR62223.1 - 0.00036 20.0 0.0 0.00081 18.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NikR_C PF08753.11 KIR62223.1 - 0.23 11.7 0.1 2.2 8.5 0.0 2.5 3 0 0 3 3 3 0 NikR C terminal nickel binding domain HTH_31 PF13560.6 KIR62224.1 - 3.2e-13 49.8 3.7 3.2e-13 49.8 3.7 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain MdcG PF10620.9 KIR62224.1 - 0.0025 17.6 1.4 0.0038 17.0 0.6 1.7 2 0 0 2 2 2 1 Phosphoribosyl-dephospho-CoA transferase MdcG Pkinase PF00069.25 KIR62225.1 - 1e-38 133.3 0.0 1.6e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR62225.1 - 3e-23 82.4 0.0 4.3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR62225.1 - 9.5e-06 25.7 3.1 0.011 15.7 0.0 3.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KIR62225.1 - 0.0005 19.5 0.0 0.00086 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Transposase_20 PF02371.16 KIR62225.1 - 0.043 14.1 1.2 0.5 10.7 0.1 2.5 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Aldedh PF00171.22 KIR62225.1 - 0.21 10.0 0.7 0.31 9.5 0.7 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Pkinase_fungal PF17667.1 KIR62225.1 - 0.24 10.2 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MarR_2 PF12802.7 KIR62225.1 - 1.4 8.8 7.4 1.7 8.6 0.3 4.0 4 1 0 4 4 4 0 MarR family DUF2154 PF09922.9 KIR62226.1 - 0.00073 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF Esterase PF00756.20 KIR62227.1 - 6.3e-31 107.9 0.0 7.9e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF3327 PF11806.8 KIR62227.1 - 1.1e-08 35.8 2.3 7.8e-07 29.8 2.3 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3327) Peptidase_S9 PF00326.21 KIR62227.1 - 2.9e-06 26.9 0.3 7.4e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIR62227.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TetR_C_16 PF17920.1 KIR62227.1 - 0.059 13.6 0.9 0.14 12.4 0.9 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_3 PF07859.13 KIR62227.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Patatin PF01734.22 KIR62227.1 - 0.17 12.0 2.5 0.32 11.2 2.1 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase STAS_2 PF13466.6 KIR62228.1 - 2.1e-13 50.4 1.0 2.7e-13 50.0 1.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KIR62228.1 - 5.2e-08 32.5 0.0 6.7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 STAS domain BPD_transp_1 PF00528.22 KIR62230.1 - 3.2e-27 95.4 19.9 3.2e-27 95.4 19.9 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ADH_zinc_N PF00107.26 KIR62231.1 - 2.2e-28 98.8 0.4 3.6e-28 98.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR62231.1 - 4.9e-24 84.3 0.0 8.8e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIR62231.1 - 3e-22 80.1 0.5 5.3e-22 79.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HTH_18 PF12833.7 KIR62232.1 - 1.4e-18 66.9 0.6 2.5e-18 66.1 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR62232.1 - 1.6e-06 28.0 0.0 0.083 13.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 KIR62232.1 - 0.00037 20.6 6.7 0.0059 16.7 0.2 3.7 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR62232.1 - 0.12 11.8 0.2 0.56 9.7 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 SUKH-4 PF14435.6 KIR62233.1 - 6.5e-17 62.1 3.7 7.4e-17 61.9 3.7 1.0 1 0 0 1 1 1 1 SUKH-4 immunity protein DUF3817 PF12823.7 KIR62234.1 - 5e-23 81.7 2.8 5.7e-23 81.5 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) DUF4383 PF14325.6 KIR62235.1 - 2.8e-44 150.4 15.9 3.2e-44 150.2 15.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF2162 PF09930.9 KIR62235.1 - 0.0041 16.6 0.5 0.0041 16.6 0.5 1.7 2 0 0 2 2 2 1 Predicted transporter (DUF2162) SfLAP PF11139.8 KIR62235.1 - 0.024 14.1 0.5 0.024 14.1 0.5 2.2 1 1 1 2 2 2 0 Sap, sulfolipid-1-addressing protein DUF4395 PF14340.6 KIR62235.1 - 0.23 11.8 4.3 0.15 12.4 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) GFO_IDH_MocA PF01408.22 KIR62236.1 - 1.3e-22 80.9 0.1 2.1e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ox_reductase_C PF08635.10 KIR62236.1 - 1.3e-09 37.8 0.0 8.6e-06 25.5 0.0 2.5 2 1 0 2 2 2 2 Putative oxidoreductase C terminal domain GFO_IDH_MocA_C PF02894.17 KIR62236.1 - 4.6e-08 33.1 0.0 7.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KIR62236.1 - 0.0013 19.2 0.1 0.0022 18.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR62236.1 - 0.0026 17.2 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIR62236.1 - 0.038 14.2 0.3 0.15 12.3 0.3 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIR62236.1 - 0.039 14.5 0.1 0.082 13.5 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ANTAR PF03861.14 KIR62237.1 - 1.7e-11 43.7 0.8 4.1e-11 42.5 0.8 1.7 1 0 0 1 1 1 1 ANTAR domain GAF_2 PF13185.6 KIR62237.1 - 5.6e-10 39.7 4.4 8.4e-10 39.1 1.8 2.3 2 1 0 2 2 2 1 GAF domain GAF PF01590.26 KIR62237.1 - 7.4e-06 26.6 0.8 1.5e-05 25.7 0.2 1.7 2 0 0 2 2 2 1 GAF domain S-methyl_trans PF02574.16 KIR62239.1 - 1.8e-63 214.9 0.1 3.1e-63 214.1 0.1 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 KIR62239.1 - 3.1e-43 148.2 0.0 6.8e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Pterin binding enzyme Met_synt_B12 PF02965.17 KIR62239.1 - 2e-37 129.2 0.0 3.2e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding_2 PF02607.17 KIR62239.1 - 9.3e-27 93.3 0.2 1.3e-25 89.6 0.1 2.8 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 KIR62239.1 - 1.3e-20 73.6 0.2 2.5e-19 69.5 0.3 2.8 3 0 0 3 3 3 1 B12 binding domain CM_2 PF01817.21 KIR62239.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.9 1 0 0 1 1 1 0 Chorismate mutase type II GCD14_N PF14801.6 KIR62241.1 - 3.1e-29 100.6 0.8 5.6e-29 99.7 0.8 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 KIR62241.1 - 6e-21 75.2 0.0 4.4e-20 72.4 0.0 2.2 1 1 2 3 3 3 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KIR62241.1 - 6.4e-06 26.8 0.0 1.5e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIR62241.1 - 3e-05 23.9 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIR62241.1 - 0.00065 19.5 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIR62241.1 - 0.0037 16.4 0.0 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 KIR62241.1 - 0.0039 18.2 0.4 0.011 16.7 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62241.1 - 0.012 16.4 0.0 0.029 15.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIR62241.1 - 0.025 14.4 0.0 0.079 12.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIR62241.1 - 0.032 14.9 0.0 0.08 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2269 PF10027.9 KIR62242.1 - 0.013 15.5 0.9 0.014 15.5 0.9 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF898 PF05987.13 KIR62242.1 - 0.046 12.8 0.4 0.051 12.6 0.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Rieske PF00355.26 KIR62243.1 - 7.2e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KIR62243.1 - 0.038 13.9 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain BPD_transp_1 PF00528.22 KIR62245.1 - 9e-17 61.4 16.4 9e-17 61.4 16.4 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DHO_dh PF01180.21 KIR62246.1 - 5.4e-44 150.6 0.0 6.1e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 KIR62246.1 - 1e-09 38.2 5.9 3e-09 36.7 0.9 2.3 2 1 0 2 2 2 1 Nitronate monooxygenase Dus PF01207.17 KIR62246.1 - 2.2e-08 33.6 0.6 0.0027 16.9 0.1 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KIR62246.1 - 6.3e-06 25.8 0.1 2.4e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 KIR62246.1 - 0.00011 21.4 2.5 0.00068 18.8 2.5 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KIR62246.1 - 0.0004 19.5 2.1 0.00095 18.3 1.5 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KIR62246.1 - 0.0012 18.2 2.3 0.0063 15.9 0.2 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 KIR62246.1 - 0.0073 15.5 1.7 0.08 12.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 KIR62246.1 - 0.054 12.9 0.3 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NanE PF04131.14 KIR62246.1 - 0.15 11.2 1.5 0.5 9.5 0.1 2.1 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KIR62246.1 - 0.37 10.1 2.5 3.7 6.8 0.2 3.0 3 1 0 3 3 3 0 Thiamine monophosphate synthase Peptidase_M20 PF01546.28 KIR62247.1 - 1e-27 97.2 0.7 1.3e-27 96.8 0.7 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KIR62247.1 - 1.4e-08 34.7 0.6 7.7e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M28 DHODB_Fe-S_bind PF10418.9 KIR62248.1 - 1.2e-09 37.9 2.8 1.2e-09 37.9 2.8 1.7 2 0 0 2 2 2 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 KIR62248.1 - 0.0014 18.9 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.11 KIR62248.1 - 0.077 13.2 0.1 6.1 7.1 0.1 2.4 1 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain Met_synt_B12 PF02965.17 KIR62249.1 - 8.5e-98 327.2 0.0 1.7e-97 326.1 0.0 1.5 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 KIR62249.1 - 1.2e-74 251.5 0.0 2e-74 250.8 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 KIR62249.1 - 5.9e-51 173.5 1.5 3.8e-50 170.8 0.2 2.4 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 KIR62249.1 - 1.2e-25 89.8 1.0 3.7e-25 88.2 0.2 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 KIR62249.1 - 2.1e-20 73.0 2.7 2.3e-18 66.4 0.9 2.9 2 0 0 2 2 2 2 B12 binding domain Abhydrolase_1 PF00561.20 KIR62250.1 - 9.9e-22 77.8 0.0 2.3e-20 73.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR62250.1 - 3.6e-07 29.7 0.1 1.8e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR62250.1 - 4.5e-07 29.9 0.2 1.3e-06 28.4 0.1 1.7 2 0 0 2 2 2 1 TAP-like protein Ser_hydrolase PF06821.13 KIR62250.1 - 0.0051 16.7 0.2 0.68 9.8 0.0 2.5 2 1 0 2 2 2 2 Serine hydrolase Peptidase_S9 PF00326.21 KIR62250.1 - 0.09 12.2 0.0 2.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family RsdA_SigD_bd PF16751.5 KIR62250.1 - 0.28 11.5 0.1 0.28 11.5 0.1 3.1 3 1 1 4 4 4 0 Anti-sigma-D factor RsdA to sigma factor binding region P53 PF00870.18 KIR62251.1 - 0.26 11.0 0.0 0.28 10.9 0.0 1.1 1 0 0 1 1 1 0 P53 DNA-binding domain Ketoacyl-synt_2 PF13723.6 KIR62253.1 - 7.3e-08 32.3 0.0 9.1e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.26 KIR62253.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Lipase_GDSL_2 PF13472.6 KIR62254.1 - 1e-14 55.4 1.1 1.2e-14 55.1 1.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR62254.1 - 0.0011 19.0 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 KIR62255.1 - 1.2e-31 110.0 55.6 5.6e-19 68.3 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIR62255.1 - 4.4e-24 84.8 38.6 6.3e-24 84.3 38.6 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 KIR62255.1 - 0.005 15.8 1.2 0.005 15.8 1.2 4.1 3 1 1 4 4 4 3 Sugar (and other) transporter MFS_1_like PF12832.7 KIR62255.1 - 0.013 14.3 14.0 0.019 13.8 3.5 3.0 1 1 0 2 2 2 0 MFS_1 like family Lipase_GDSL_2 PF13472.6 KIR62256.1 - 3.9e-18 66.5 0.9 6.7e-18 65.7 0.9 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR62256.1 - 1.9e-05 24.8 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KIR62256.1 - 0.25 10.6 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 OSK domain FMN_dh PF01070.18 KIR62257.1 - 8.6e-122 406.5 3.1 1.1e-121 406.2 3.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KIR62257.1 - 0.00013 21.5 6.4 0.00021 20.8 6.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIR62257.1 - 0.00076 18.6 1.8 0.0023 17.0 1.8 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIR62257.1 - 0.0011 18.2 2.0 0.0036 16.5 1.9 1.7 1 1 1 2 2 2 1 Conserved region in glutamate synthase ThiG PF05690.14 KIR62257.1 - 0.0044 16.4 3.0 0.86 8.9 0.1 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KIR62257.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 KIR62257.1 - 0.23 10.8 1.1 1.7 7.9 0.0 2.6 3 0 0 3 3 3 0 Thiamine monophosphate synthase Arch_flagellin PF01917.16 KIR62259.1 - 7 6.8 6.9 5.8 7.1 4.0 1.9 2 0 0 2 2 2 0 Archaebacterial flagellin Methyltransf_19 PF04672.12 KIR62260.1 - 3e-103 345.0 1.1 3.3e-103 344.8 1.1 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_31 PF13847.6 KIR62260.1 - 0.0086 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR62260.1 - 0.015 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIR62260.1 - 0.067 13.9 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain E1_dh PF00676.20 KIR62261.1 - 5.4e-74 248.8 0.0 6.9e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KIR62261.1 - 0.00013 21.3 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 KIR62261.1 - 0.032 13.2 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain FKBP_C PF00254.28 KIR62262.1 - 3.5e-31 107.4 0.0 4.3e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DoxX PF07681.12 KIR62263.1 - 2.3e-06 28.1 11.0 2.3e-06 28.1 11.0 2.2 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 KIR62263.1 - 0.059 13.3 1.4 0.1 12.5 1.2 1.4 1 1 0 1 1 1 0 TQO small subunit DoxD DICT PF10069.9 KIR62264.1 - 4e-13 49.2 0.0 7.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Sensory domain in DIguanylate Cyclases and Two-component system GGDEF PF00990.21 KIR62264.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain ArsB PF02040.15 KIR62265.1 - 3.2e-25 89.3 8.9 4.1e-25 89.0 8.9 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 KIR62265.1 - 7.3e-20 71.3 29.9 7.3e-20 71.3 29.9 2.2 1 1 1 2 2 2 1 Citrate transporter ABC_tran PF00005.27 KIR62266.1 - 1.2e-30 106.8 0.0 1.7e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR62266.1 - 1.1e-05 25.1 0.0 0.022 14.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR62266.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIR62266.1 - 4.3e-05 23.5 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR62266.1 - 0.00027 21.4 0.2 0.00053 20.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KIR62266.1 - 0.00042 20.9 0.0 0.00059 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR62266.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIR62266.1 - 0.0031 17.8 0.1 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIR62266.1 - 0.0037 16.9 0.3 0.063 12.8 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIR62266.1 - 0.0056 16.4 2.3 0.088 12.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIR62266.1 - 0.01 16.1 0.6 0.74 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR62266.1 - 0.061 13.5 0.1 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIR62266.1 - 0.065 13.2 0.2 0.47 10.3 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KIR62266.1 - 0.085 12.6 0.1 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIR62266.1 - 0.12 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KIR62266.1 - 0.19 11.8 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain FtsX PF02687.21 KIR62267.1 - 5e-17 62.2 16.8 8.7e-11 42.1 4.7 6.4 6 1 1 7 7 7 2 FtsX-like permease family MacB_PCD PF12704.7 KIR62267.1 - 9.6e-15 55.4 24.9 6.5e-10 39.7 10.1 5.0 4 1 1 5 5 5 2 MacB-like periplasmic core domain DUF1622 PF07784.11 KIR62268.1 - 6.6e-28 96.4 0.8 8.4e-28 96.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1622) DUF3598 PF12204.8 KIR62268.1 - 0.12 11.9 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) DUF4012 PF13196.6 KIR62269.1 - 4.7e-46 156.8 0.0 2e-45 154.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4012) TPR_21 PF09976.9 KIR62269.1 - 0.0081 15.9 0.5 0.017 14.9 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain PAP_PilO PF06864.12 KIR62269.1 - 0.022 13.6 1.1 0.035 12.9 1.1 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DENN PF02141.21 KIR62269.1 - 0.25 11.3 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain BMFP PF04380.13 KIR62269.1 - 0.79 10.2 3.3 3 8.4 0.1 3.0 2 1 0 2 2 2 0 Membrane fusogenic activity MFS_1 PF07690.16 KIR62270.1 - 1.7e-54 185.1 52.4 6.1e-38 130.6 22.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIR62270.1 - 1.2e-06 27.2 9.0 1.2e-06 27.2 9.0 2.3 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIR62270.1 - 5e-05 22.3 7.7 0.00026 20.0 1.5 2.3 2 0 0 2 2 2 2 MFS_1 like family Rio2_N PF09202.11 KIR62271.1 - 0.0097 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Rio2, N-terminal TrmB PF01978.19 KIR62271.1 - 0.12 12.2 0.1 0.69 9.8 0.1 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 KIR62271.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Polysacc_deac_1 PF01522.21 KIR62272.1 - 3.2e-27 94.9 0.0 5.3e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 KIR62272.1 - 0.024 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Virulence protein nec1 Peptidase_M15 PF01427.17 KIR62273.1 - 4.8e-41 140.7 0.0 4.9e-21 75.4 0.0 2.0 2 0 0 2 2 2 2 D-ala-D-ala dipeptidase VanY PF02557.17 KIR62273.1 - 0.015 15.1 3.1 0.41 10.4 0.1 2.7 2 2 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MFS_1 PF07690.16 KIR62274.1 - 1.1e-21 77.1 42.2 2.2e-15 56.5 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIR62274.1 - 0.0035 15.8 31.0 0.0044 15.5 31.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector TauD PF02668.16 KIR62275.1 - 5.9e-44 150.9 1.3 7.8e-44 150.5 1.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short_C2 PF13561.6 KIR62276.1 - 4.7e-57 193.2 3.9 2.2e-56 191.0 3.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR62276.1 - 5.6e-49 166.3 0.9 3e-48 163.9 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR62276.1 - 6.3e-10 39.3 0.5 9.4e-10 38.7 0.5 1.2 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 KIR62277.1 - 1.8e-102 343.1 0.2 6.5e-101 338.0 0.2 2.1 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIR62277.1 - 1e-13 51.4 0.0 2.7e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR62277.1 - 4.2e-06 27.6 3.5 4.2e-06 27.6 3.5 3.4 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KIR62277.1 - 0.13 10.9 0.0 0.6 8.7 0.0 1.8 2 0 0 2 2 2 0 Condensation domain VTC PF09359.10 KIR62278.1 - 1.2e-14 54.4 0.0 4.4e-09 36.2 0.0 3.0 2 1 0 2 2 2 2 VTC domain Thioredoxin PF00085.20 KIR62279.1 - 3.1e-07 30.3 0.0 3.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KIR62279.1 - 0.00012 22.0 0.1 0.00016 21.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KIR62279.1 - 0.0019 18.6 0.0 0.034 14.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 KIR62279.1 - 0.0042 17.3 0.1 0.0072 16.5 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 KIR62279.1 - 0.0079 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KIR62279.1 - 0.039 14.3 0.0 0.94 9.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_4 PF13462.6 KIR62279.1 - 0.26 11.4 0.1 4.1 7.5 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin BPD_transp_1 PF00528.22 KIR62280.1 - 5e-28 98.1 38.1 3.8e-15 56.1 15.4 2.7 2 1 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component MFS_1 PF07690.16 KIR62281.1 - 3.8e-33 114.9 43.1 3.8e-33 114.9 43.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR62281.1 - 8.9e-10 38.0 4.0 1.8e-09 37.0 4.0 1.5 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 KIR62281.1 - 0.00049 19.2 1.7 0.00049 19.2 1.7 2.5 2 1 1 3 3 3 1 Nucleoside H+ symporter LacY_symp PF01306.19 KIR62281.1 - 0.4 9.4 5.5 0.03 13.1 0.9 1.5 2 0 0 2 2 2 0 LacY proton/sugar symporter Methyltransf_25 PF13649.6 KIR62282.1 - 2.4e-19 69.8 0.5 3.9e-19 69.2 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR62282.1 - 7e-16 58.7 0.2 1e-15 58.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR62282.1 - 6.5e-15 55.4 0.0 9.3e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62282.1 - 2.3e-13 50.7 0.1 4.6e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR62282.1 - 3.6e-11 43.1 0.0 4.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KIR62282.1 - 2.2e-06 27.5 0.0 3.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KIR62282.1 - 0.00015 21.2 0.0 0.0002 20.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KIR62282.1 - 0.0046 16.3 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 KIR62282.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF1571 PF07608.11 KIR62282.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) TPMT PF05724.11 KIR62282.1 - 0.024 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KIR62282.1 - 0.056 13.0 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KIR62282.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KIR62282.1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPD_transp_1 PF00528.22 KIR62283.1 - 1.8e-26 93.0 7.0 1.8e-26 93.0 7.0 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KIR62284.1 - 1.7e-49 167.8 0.0 1.4e-23 83.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 KIR62284.1 - 5.5e-11 42.9 3.7 1.9e-05 25.0 0.3 3.9 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KIR62284.1 - 3.4e-09 36.9 0.1 0.076 12.8 0.0 4.0 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR62284.1 - 3.2e-07 30.9 17.1 2e-06 28.3 2.9 3.2 1 1 1 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KIR62284.1 - 1.1e-06 28.3 1.0 0.023 14.1 0.0 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR62284.1 - 6.5e-06 25.8 0.5 0.075 12.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain oligo_HPY PF08352.12 KIR62284.1 - 0.00041 20.8 0.0 0.44 11.1 0.0 2.5 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_33 PF13671.6 KIR62284.1 - 0.00084 19.5 9.6 0.21 11.8 3.0 3.5 2 1 0 2 2 2 2 AAA domain MobB PF03205.14 KIR62284.1 - 0.0016 18.4 0.2 1.2 9.0 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 KIR62284.1 - 0.0041 17.1 2.2 0.54 10.2 0.1 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 KIR62284.1 - 0.0042 17.2 0.7 4 7.6 0.1 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR62284.1 - 0.005 16.8 0.5 4 7.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 KIR62284.1 - 0.0057 15.9 2.5 0.39 9.9 0.2 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KIR62284.1 - 0.014 15.1 0.8 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KIR62284.1 - 0.014 15.1 2.1 4.1 7.1 0.1 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KIR62284.1 - 0.017 15.1 1.9 2.8 7.9 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KIR62284.1 - 0.017 14.9 2.4 5.9 6.6 0.1 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIR62284.1 - 0.02 14.3 3.9 0.13 11.6 0.3 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIR62284.1 - 0.02 14.4 20.8 0.56 9.8 7.8 3.8 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIR62284.1 - 0.021 15.4 0.7 2.3 8.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIR62284.1 - 0.022 15.3 3.0 6.1 7.4 0.3 3.1 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 KIR62284.1 - 0.023 15.1 5.7 3.3 8.1 0.7 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIR62284.1 - 0.03 13.7 0.4 4.7 6.6 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 KIR62284.1 - 0.053 12.9 1.6 6.1 6.1 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 KIR62284.1 - 0.082 11.9 1.5 1.6 7.7 0.1 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein Pox_A32 PF04665.12 KIR62284.1 - 0.086 12.3 2.1 4.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein PRK PF00485.18 KIR62284.1 - 0.14 11.9 0.7 8.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Resolvase PF00239.21 KIR62284.1 - 0.15 12.1 2.1 0.38 10.9 0.3 2.5 2 0 0 2 2 2 0 Resolvase, N terminal domain ABC_ATPase PF09818.9 KIR62284.1 - 0.22 10.3 1.8 11 4.6 0.0 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF927 PF06048.11 KIR62284.1 - 0.26 10.8 0.2 13 5.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF927) cobW PF02492.19 KIR62284.1 - 0.34 10.5 1.1 22 4.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KIR62284.1 - 0.65 10.0 3.9 5.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KIR62284.1 - 0.76 8.6 3.0 16 4.3 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 KIR62284.1 - 0.82 9.3 2.8 16 5.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KIR62284.1 - 0.86 9.6 4.9 12 5.9 0.2 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIR62284.1 - 0.91 9.2 23.6 0.83 9.3 0.9 4.3 4 1 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 KIR62284.1 - 1.2 9.0 3.5 15 5.4 0.1 3.1 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 KIR62284.1 - 2.1 7.6 5.9 4.3 6.6 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 KIR62284.1 - 7 7.0 5.8 20 5.5 0.9 2.9 3 0 0 3 3 2 0 AAA domain DinB_2 PF12867.7 KIR62284.1 - 8 7.0 8.5 0.3 11.6 0.2 2.8 2 1 0 2 2 1 0 DinB superfamily AAA_28 PF13521.6 KIR62284.1 - 8.5 6.6 6.9 51 4.1 0.5 3.5 2 1 0 3 3 3 0 AAA domain DUF2929 PF11151.8 KIR62285.1 - 0.72 10.2 5.6 0.58 10.5 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2929) HATPase_c PF02518.26 KIR62286.1 - 1.4e-21 77.1 0.0 3.7e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR62286.1 - 3.4e-14 52.6 1.5 1.1e-13 51.0 1.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR62286.1 - 1.1e-10 41.7 4.6 1.9e-10 40.9 0.2 3.0 3 0 0 3 3 3 1 HAMP domain HATPase_c_3 PF13589.6 KIR62286.1 - 0.0016 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR62286.1 - 0.0025 17.8 0.1 0.0077 16.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Peripla_BP_3 PF13377.6 KIR62287.1 - 1.3e-28 100.4 0.4 2.3e-28 99.6 0.4 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR62287.1 - 7.7e-17 60.8 0.6 1.9e-16 59.6 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 KIR62287.1 - 5.3e-10 39.2 0.0 6.8e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_3 PF01381.22 KIR62287.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix TetR_N PF00440.23 KIR62287.1 - 0.13 12.1 3.2 0.22 11.4 0.1 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family ROK PF00480.20 KIR62288.1 - 5.9e-45 154.0 0.0 7.6e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR62288.1 - 2.4e-06 27.3 0.8 2.4e-06 27.3 0.8 3.0 3 0 0 3 3 3 1 MarR family HTH_IclR PF09339.10 KIR62288.1 - 1.9e-05 24.4 0.2 1.9e-05 24.4 0.2 3.1 4 0 0 4 4 4 1 IclR helix-turn-helix domain HTH_27 PF13463.6 KIR62288.1 - 0.00022 21.6 0.1 0.00051 20.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 KIR62288.1 - 0.00026 20.9 0.4 0.00088 19.2 0.1 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KIR62288.1 - 0.00045 19.7 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR62288.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR62288.1 - 0.016 15.3 0.6 0.076 13.1 0.6 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 KIR62288.1 - 0.02 14.8 0.0 0.083 12.9 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain SMC_ScpB PF04079.16 KIR62288.1 - 0.041 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Glyco_hydro_42 PF02449.15 KIR62289.1 - 1.4e-121 406.4 0.0 4e-120 401.6 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 KIR62289.1 - 8.5e-49 165.9 0.0 1.9e-48 164.7 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.10 KIR62289.1 - 8.2e-09 35.1 0.0 2.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Glyco_hydro_14 PF01373.17 KIR62289.1 - 0.0049 15.9 0.0 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 14 DUF4434 PF14488.6 KIR62289.1 - 0.076 13.0 0.7 4.3 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4434) DUF5632 PF18646.1 KIR62289.1 - 0.36 10.9 2.8 13 5.9 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5632) CE2_N PF17996.1 KIR62290.1 - 1.8e-23 82.6 0.1 6.5e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal CBM_2 PF00553.19 KIR62290.1 - 1e-14 54.7 6.8 3.1e-14 53.1 6.8 1.9 1 0 0 1 1 1 1 Cellulose binding domain Lipase_GDSL_2 PF13472.6 KIR62290.1 - 3.3e-11 43.9 2.3 3.3e-11 43.9 2.3 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR62290.1 - 3.7e-08 33.6 0.0 5.5e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Phage_T4_gp36 PF03903.13 KIR62290.1 - 0.013 15.5 1.5 0.096 12.6 0.2 2.5 2 0 0 2 2 2 0 Phage T4 tail fibre HATPase_c PF02518.26 KIR62291.1 - 1.9e-20 73.4 0.0 3.5e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR62291.1 - 3.4e-16 59.0 0.6 3.4e-16 59.0 0.6 2.7 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR62291.1 - 2.8e-10 40.4 2.1 1.1e-09 38.6 2.1 2.1 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 KIR62291.1 - 3.2e-06 27.1 0.2 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Radical_SAM PF04055.21 KIR62292.1 - 0.00037 20.9 0.6 0.073 13.4 0.6 2.3 1 1 0 1 1 1 1 Radical SAM superfamily Mago-bind PF09282.10 KIR62292.1 - 0.039 13.8 0.7 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Mago binding Sulfatase PF00884.23 KIR62293.1 - 1.8e-12 47.3 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KIR62293.1 - 3.2e-07 30.3 0.1 0.00038 20.2 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KIR62293.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily CBP_BcsG PF11658.8 KIR62293.1 - 0.014 13.8 0.0 0.019 13.4 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Cyclase PF04199.13 KIR62294.1 - 2.2e-22 79.7 0.1 3.1e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase DUF1232 PF06803.12 KIR62295.1 - 2e-11 43.5 7.3 2e-11 43.5 7.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) Inhibitor_I36 PF03995.13 KIR62296.1 - 0.41 10.6 6.2 1.4 8.9 6.2 1.9 1 1 0 1 1 1 0 Peptidase inhibitor family I36 ECF-ribofla_trS PF07155.12 KIR62297.1 - 0.03 14.3 7.7 0.14 12.1 7.4 2.0 1 1 0 1 1 1 0 ECF-type riboflavin transporter, S component Romo1 PF10247.9 KIR62297.1 - 3.5 8.1 7.0 1.5 9.2 0.5 2.9 3 1 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Aminotran_5 PF00266.19 KIR62298.1 - 3e-37 128.5 0.0 2.6e-36 125.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V MDMPI_N PF11716.8 KIR62299.1 - 5.8e-08 33.5 5.8 8.3e-07 29.8 3.5 2.6 1 1 1 2 2 2 2 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 KIR62299.1 - 0.00058 20.7 4.4 0.00058 20.7 4.4 2.3 2 0 0 2 2 2 1 MDMPI C-terminal domain DinB_2 PF12867.7 KIR62299.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 DinB superfamily p450 PF00067.22 KIR62300.1 - 5.4e-86 289.2 0.0 6.6e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flavin_Reduct PF01613.18 KIR62301.1 - 2.1e-37 128.5 0.0 2.4e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain ketoacyl-synt PF00109.26 KIR62302.1 - 5.8e-53 180.0 0.7 1.7e-52 178.5 0.0 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KIR62302.1 - 2.2e-43 148.6 2.6 6.1e-43 147.2 2.6 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KIR62302.1 - 3.5e-30 104.5 1.5 9.8e-30 103.0 1.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 KIR62302.1 - 1e-28 100.5 0.0 4.7e-28 98.3 0.0 2.2 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KIR62302.1 - 6.4e-22 78.5 0.3 1.6e-21 77.2 0.3 1.6 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.25 KIR62302.1 - 7.4e-13 48.4 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KIR62302.1 - 5.1e-09 36.6 0.0 9.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 KIR62302.1 - 7.1e-07 29.0 1.7 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KIR62302.1 - 0.00011 22.4 0.2 0.015 15.7 0.1 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KIR62302.1 - 0.0013 18.2 0.2 0.0029 17.0 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain FabA PF07977.13 KIR62302.1 - 0.14 11.8 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 FabA-like domain VCBS PF13517.6 KIR62303.1 - 1.5e-18 67.1 15.3 8.1e-06 26.3 0.2 6.2 4 3 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 KIR62303.1 - 1.1e-13 50.9 1.6 2.6e-13 49.7 1.6 1.6 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 KIR62303.1 - 1.9e-06 27.9 10.4 0.00011 22.3 0.3 4.5 4 0 0 4 4 4 2 FG-GAP repeat Pro_Al_protease PF02983.14 KIR62303.1 - 0.0015 18.5 0.0 0.0048 16.9 0.0 1.8 1 0 0 1 1 1 1 Alpha-lytic protease prodomain Peptidase_M20 PF01546.28 KIR62304.1 - 1.3e-23 83.8 0.1 3.8e-22 79.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIR62304.1 - 2.2e-15 56.5 0.1 3.5e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIR62304.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 HTH_17 PF12728.7 KIR62305.1 - 1.8e-10 40.8 0.0 3.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 KIR62305.1 - 2e-10 40.2 0.1 3.3e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 MerR family regulatory protein TOBE PF03459.17 KIR62305.1 - 5.4e-10 39.4 2.0 5.4e-10 39.4 2.0 1.7 2 0 0 2 2 2 1 TOBE domain MerR_1 PF13411.6 KIR62305.1 - 3.1e-07 30.4 0.0 5.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_29 PF13551.6 KIR62305.1 - 7.2e-05 22.7 0.3 0.00016 21.6 0.2 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIR62305.1 - 0.00045 19.9 0.1 0.0012 18.6 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KIR62305.1 - 0.0005 20.1 0.1 0.00097 19.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR62305.1 - 0.00084 18.7 0.1 0.0025 17.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 AbiEi_4 PF13338.6 KIR62305.1 - 0.0036 17.4 0.2 0.0079 16.3 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin HTH_DeoR PF08220.12 KIR62305.1 - 0.0042 16.8 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_31 PF13560.6 KIR62305.1 - 0.0078 16.5 5.1 0.043 14.2 5.1 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain DUF746 PF05344.11 KIR62305.1 - 0.018 14.8 0.2 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_Tnp_IS630 PF01710.16 KIR62305.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Transposase Sigma70_r4_2 PF08281.12 KIR62305.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 KIR62305.1 - 0.31 10.8 1.2 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family ABC_tran PF00005.27 KIR62306.1 - 9.5e-33 113.6 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 KIR62306.1 - 2.8e-14 53.2 0.4 2.8e-14 53.2 0.4 2.8 3 0 0 3 3 3 1 TOBE domain AAA_21 PF13304.6 KIR62306.1 - 4.4e-08 33.3 0.0 1.8e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 KIR62306.1 - 0.00035 20.7 4.9 0.0014 18.8 0.4 3.4 3 0 0 3 3 3 1 TOBE domain TOBE_3 PF12857.7 KIR62306.1 - 0.0018 18.1 0.4 0.012 15.5 0.1 2.6 2 0 0 2 2 2 1 TOBE-like domain SMC_N PF02463.19 KIR62306.1 - 0.0021 17.5 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR62306.1 - 0.004 16.9 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR62306.1 - 0.0041 17.6 0.0 0.0055 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR62306.1 - 0.0084 15.8 0.1 0.027 14.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR62306.1 - 0.0087 16.2 0.2 0.032 14.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR62306.1 - 0.016 15.5 0.2 0.034 14.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KIR62306.1 - 0.037 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIR62306.1 - 0.054 13.1 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIR62306.1 - 0.06 13.6 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR62306.1 - 0.072 13.5 2.9 0.24 11.8 2.8 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KIR62306.1 - 0.096 13.1 0.0 0.42 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIR62306.1 - 0.2 11.6 0.2 0.41 10.6 0.1 1.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KIR62306.1 - 0.25 11.4 0.1 0.44 10.6 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NR_Repeat PF14046.6 KIR62306.1 - 5.1 7.3 5.8 0.76 10.0 1.0 2.1 2 0 0 2 2 2 0 Nuclear receptor repeat Aldo_ket_red PF00248.21 KIR62307.1 - 1.3e-42 146.0 0.0 8.6e-42 143.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Porphobil_deam PF01379.20 KIR62307.1 - 0.069 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain Fer4_13 PF13370.6 KIR62308.1 - 2.1e-12 47.4 0.1 2.4e-12 47.2 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KIR62308.1 - 5.6e-12 46.2 1.9 6.8e-12 46.0 1.9 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 KIR62308.1 - 2.8e-11 43.3 0.1 3.1e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 KIR62308.1 - 0.24 11.3 7.5 0.33 10.8 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KIR62308.1 - 0.89 9.7 7.7 4.8 7.4 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DUF3626 PF12294.8 KIR62309.1 - 7.8e-120 399.5 0.0 9.2e-120 399.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) SpoIIE PF07228.12 KIR62310.1 - 3.1e-32 112.0 1.5 8.7e-32 110.6 1.2 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIR62310.1 - 0.061 12.9 1.0 0.64 9.6 0.9 2.5 1 1 0 1 1 1 0 Protein phosphatase 2C NO_synthase PF02898.15 KIR62311.1 - 5.7e-122 407.2 0.0 6.6e-122 407.0 0.0 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain DivIVA PF05103.13 KIR62312.1 - 0.0044 17.1 5.0 0.0044 17.1 5.0 2.7 1 1 1 2 2 2 1 DivIVA protein CCDC92 PF14916.6 KIR62312.1 - 0.021 14.6 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Striatin PF08232.12 KIR62312.1 - 0.039 14.5 3.1 0.11 13.1 3.1 1.7 1 1 0 1 1 1 0 Striatin family ZapB PF06005.12 KIR62312.1 - 0.14 12.6 9.2 0.14 12.6 0.3 2.4 2 1 0 2 2 2 0 Cell division protein ZapB FlaC_arch PF05377.11 KIR62312.1 - 0.23 11.9 0.2 1.2 9.6 0.0 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Viral_P18 PF04521.13 KIR62312.1 - 0.55 10.0 1.9 3.8 7.3 0.3 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HrpE PF06188.12 KIR62312.1 - 1.5 8.6 15.6 0.06 13.2 7.2 2.3 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E FR47 PF08445.10 KIR62313.1 - 1.9e-12 46.9 0.3 3.2e-12 46.2 0.3 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KIR62313.1 - 1.3e-09 38.3 0.1 2.1e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR62313.1 - 6e-06 26.6 0.1 1.1e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR62313.1 - 1.2e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR62313.1 - 0.00016 21.7 0.1 0.00036 20.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KIR62313.1 - 0.0025 17.4 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 KIR62313.1 - 0.013 16.2 0.0 0.022 15.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR62313.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HxlR PF01638.17 KIR62314.1 - 1.6e-21 76.0 0.0 1.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 KIR62314.1 - 0.00015 21.7 0.6 0.00025 21.0 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain PadR PF03551.14 KIR62314.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 KIR62314.1 - 0.18 11.9 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation THF_DHG_CYH_C PF02882.19 KIR62315.1 - 6.4e-45 152.3 1.7 2.1e-44 150.7 0.4 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KIR62315.1 - 3.9e-28 98.0 0.0 5.3e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain zf-dskA_traR PF01258.17 KIR62316.1 - 1.3e-12 47.4 5.1 2.2e-12 46.7 5.1 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger TC1 PF15063.6 KIR62316.1 - 0.0021 17.9 0.6 0.0028 17.5 0.6 1.2 1 0 0 1 1 1 1 Thyroid cancer protein 1 Neisseria_TspB PF05616.13 KIR62317.1 - 0.045 12.2 3.8 0.059 11.8 3.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4140 PF13600.6 KIR62317.1 - 2.5 8.6 7.5 4.6 7.7 2.9 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TetR_N PF00440.23 KIR62318.1 - 1.7e-12 47.0 0.8 3.8e-12 45.8 0.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 KIR62318.1 - 5.9e-05 23.8 9.3 5.9e-05 23.8 9.3 2.8 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 KIR62318.1 - 0.00097 19.4 0.4 0.0087 16.3 0.0 2.4 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 KIR62318.1 - 0.0075 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 KIR62318.1 - 0.046 13.5 1.6 0.093 12.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family LigT_PEase PF02834.16 KIR62318.1 - 0.046 13.9 0.5 0.095 12.9 0.5 1.5 1 0 0 1 1 1 0 LigT like Phosphoesterase HTH_32 PF13565.6 KIR62318.1 - 0.37 11.4 4.3 0.48 11.1 0.1 2.6 2 1 0 2 2 2 0 Homeodomain-like domain RbpA PF13397.6 KIR62319.1 - 3e-43 146.7 0.2 3.4e-43 146.5 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase-binding protein Glycos_transf_2 PF00535.26 KIR62320.1 - 7.6e-29 100.7 0.0 1.1e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR62320.1 - 2.9e-10 40.4 0.6 3.4e-10 40.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Lipase_GDSL_2 PF13472.6 KIR62320.1 - 0.044 14.2 0.8 0.35 11.2 0.3 2.4 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family OAM_dimer PF16554.5 KIR62321.1 - 2.9e-33 114.1 0.1 4.8e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of d-ornithine 4,5-aminomutase B12-binding PF02310.19 KIR62321.1 - 5.7e-21 74.8 0.3 8.2e-21 74.3 0.3 1.2 1 0 0 1 1 1 1 B12 binding domain Amidohydro_3 PF07969.11 KIR62322.1 - 3.6e-72 244.3 14.8 4.1e-72 244.1 14.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIR62322.1 - 3.1e-07 30.0 0.0 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_M23 PF01551.22 KIR62323.1 - 3e-18 65.8 0.9 4.6e-18 65.2 0.9 1.3 1 0 0 1 1 1 1 Peptidase family M23 PG_binding_3 PF09374.10 KIR62323.1 - 1.3e-05 25.3 0.9 0.041 14.1 0.0 3.4 1 1 2 3 3 3 3 Predicted Peptidoglycan domain PG_binding_1 PF01471.18 KIR62323.1 - 3.4e-05 23.9 0.1 0.02 15.1 0.1 3.4 1 1 2 3 3 3 2 Putative peptidoglycan binding domain Apocytochr_F_C PF01333.19 KIR62323.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Apocytochrome F, C-terminal Hydrolase PF00702.26 KIR62324.1 - 2.9e-14 53.8 0.0 1.1e-13 51.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIR62324.1 - 1.3e-13 51.4 0.0 1.5e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR62324.1 - 5.4e-05 23.2 0.1 0.00014 21.8 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIR62324.1 - 0.0019 18.6 1.0 0.0043 17.5 1.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LysR_substrate PF03466.20 KIR62324.1 - 0.059 12.7 3.9 0.08 12.3 0.1 2.3 2 1 0 2 2 2 0 LysR substrate binding domain Hydrolase_6 PF13344.6 KIR62324.1 - 0.075 13.2 0.0 0.84 9.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aminotran_5 PF00266.19 KIR62325.1 - 9.5e-31 107.1 0.0 2.6e-30 105.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR62325.1 - 8.6e-08 31.1 0.0 1.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIR62325.1 - 0.004 16.5 0.1 0.0057 16.0 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-HC2 PF13490.6 KIR62326.1 - 3e-09 37.0 1.7 8.8e-09 35.5 1.7 1.9 1 0 0 1 1 1 1 Putative zinc-finger CrgA PF06781.12 KIR62326.1 - 6.2 7.0 5.3 3.1 7.9 0.3 2.4 1 1 1 2 2 2 0 Cell division protein CrgA PepSY PF03413.19 KIR62327.1 - 2.9e-07 30.9 0.5 5.4e-07 30.1 0.5 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 KIR62327.1 - 0.00022 21.2 0.7 0.00022 21.2 0.7 2.7 1 1 1 2 2 2 1 Peptidase propeptide and YPEB domain Cwf_Cwc_15 PF04889.12 KIR62327.1 - 1.9 8.1 8.6 2.2 8.0 8.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.16 KIR62328.1 - 3.3e-49 167.7 45.6 3.3e-49 167.7 45.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR62328.1 - 2.6e-05 23.3 4.6 2.6e-05 23.3 4.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KIR62328.1 - 0.00047 18.7 15.8 0.00047 18.7 15.8 2.6 3 0 0 3 3 3 1 Transmembrane secretion effector OATP PF03137.20 KIR62328.1 - 2.5 6.3 4.0 14 3.8 0.4 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Penicil_amidase PF01804.18 KIR62329.1 - 2.5e-159 532.4 14.1 3e-159 532.1 14.1 1.0 1 0 0 1 1 1 1 Penicillin amidase XPB_DRD PF18458.1 KIR62329.1 - 0.54 10.2 4.5 0.37 10.7 1.6 2.3 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain CHAT PF12770.7 KIR62330.1 - 7.1e-39 133.9 0.4 1.4e-38 132.9 0.4 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 KIR62330.1 - 4.6e-10 39.6 38.5 1e-07 32.1 0.9 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIR62330.1 - 7.5e-07 28.8 24.0 0.022 14.8 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIR62330.1 - 4.6e-05 23.0 10.1 0.0022 17.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIR62330.1 - 0.0099 15.5 0.2 0.44 10.3 0.0 3.0 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 KIR62330.1 - 0.044 13.7 0.5 0.044 13.7 0.5 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIR62330.1 - 0.09 13.0 3.6 2.5 8.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat CarboxypepD_reg PF13620.6 KIR62331.1 - 0.00057 20.1 0.3 0.001 19.3 0.3 1.5 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain F420_oxidored PF03807.17 KIR62620.1 - 1.2e-19 70.7 0.0 2.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIR62620.1 - 2.1e-08 33.7 0.1 3.3e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIR62620.1 - 4.5e-08 33.4 0.0 2.5e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIR62620.1 - 7.1e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 KIR62620.1 - 0.00014 21.7 0.3 0.00024 20.9 0.3 1.4 1 0 0 1 1 1 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KIR62620.1 - 0.00093 18.8 0.5 0.0023 17.5 0.2 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KIR62620.1 - 0.0091 15.7 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KIR62620.1 - 0.015 15.2 1.1 0.19 11.6 0.5 2.1 1 1 1 2 2 2 0 NAD(P)H-binding Shikimate_DH PF01488.20 KIR62620.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KIR62620.1 - 0.022 14.7 1.7 2.7 7.9 0.2 2.2 1 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 KIR62620.1 - 0.031 14.7 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 KIR62620.1 - 0.049 14.1 0.0 0.096 13.2 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.27 KIR62620.1 - 0.056 14.0 0.2 0.34 11.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 KIR62620.1 - 0.071 13.5 4.2 0.28 11.6 4.2 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain 3HCDH_N PF02737.18 KIR62620.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIR62620.1 - 0.16 12.3 0.5 0.86 9.9 0.5 2.2 1 1 0 1 1 1 0 TrkA-N domain tRNA-synt_1d PF00750.19 KIR62620.1 - 0.21 10.5 0.0 0.43 9.5 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (R) VanW PF04294.13 KIR62621.1 - 6.2e-43 145.6 0.0 9.8e-43 144.9 0.0 1.3 1 0 0 1 1 1 1 VanW like protein PG_binding_4 PF12229.8 KIR62621.1 - 8.1e-20 71.2 0.0 3.8e-12 46.5 0.0 3.3 3 1 1 4 4 4 3 Putative peptidoglycan binding domain Rnk_N PF14760.6 KIR62621.1 - 0.47 11.0 6.2 2.1 8.9 0.5 3.2 3 0 0 3 3 3 0 Rnk N-terminus Crr6 PF08847.11 KIR62622.1 - 0.15 11.7 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Chlororespiratory reduction 6 DUF885 PF05960.11 KIR62623.1 - 2.9e-164 548.6 2.0 3.2e-164 548.5 2.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Uma2 PF05685.12 KIR62624.1 - 0.0008 19.0 0.0 0.00094 18.8 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease HHH_8 PF14716.6 KIR62625.1 - 1.4e-12 47.8 0.9 2.8e-12 46.8 0.9 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PHP PF02811.19 KIR62625.1 - 1.6e-08 35.0 0.0 2.7e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 PHP domain Peptidase_M23 PF01551.22 KIR62626.1 - 5.5e-15 55.4 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M23 MafB19-deam PF14437.6 KIR62628.1 - 2.3e-27 95.4 0.0 3e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KIR62628.1 - 1.3e-21 76.4 0.0 2.6e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KIR62628.1 - 0.0018 18.4 2.0 0.014 15.4 1.8 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KIR62628.1 - 0.027 14.6 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 PNP_UDP_1 PF01048.20 KIR62629.1 - 2e-42 145.1 0.3 2.3e-42 144.9 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KIR62631.1 - 1.8e-08 34.5 0.0 4.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KIR62631.1 - 0.0002 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR62631.1 - 0.00043 20.7 0.1 0.0021 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KIR62631.1 - 0.00054 20.3 0.0 0.0019 18.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIR62631.1 - 0.0018 18.8 0.0 0.003 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR62631.1 - 0.0025 18.1 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR62631.1 - 0.0055 17.0 0.0 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIR62631.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KIR62631.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KIR62631.1 - 0.058 12.9 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 KIR62631.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIR62631.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIR62631.1 - 0.19 11.0 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 KIR62631.1 - 0.19 11.0 0.0 0.49 9.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KIR62631.1 - 0.2 12.2 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 KIR62631.1 - 0.21 10.5 0.0 0.5 9.2 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 KIR62631.1 - 0.24 11.4 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KIR62631.1 - 0.31 10.5 0.0 0.48 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Prok-E2_A PF14457.6 KIR62632.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Prokaryotic E2 family A BAT PF15915.5 KIR62632.1 - 0.27 11.1 5.1 1.3 8.9 4.5 2.1 1 1 1 2 2 2 0 GAF and HTH_10 associated domain FG-GAP PF01839.23 KIR62634.1 - 2.4e-38 129.9 62.2 4.1e-09 36.4 8.1 8.2 8 0 0 8 8 8 6 FG-GAP repeat VCBS PF13517.6 KIR62634.1 - 1.8e-15 57.3 41.0 9.7e-07 29.3 5.8 5.8 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 KIR62634.1 - 3.9e-05 23.8 34.0 0.19 12.0 0.2 7.0 5 1 1 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 KIR62634.1 - 0.0033 16.8 14.1 1.7 8.0 0.3 5.8 4 1 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.6 KIR62634.1 - 0.31 11.1 3.6 42 4.2 0.1 4.6 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region HTH_31 PF13560.6 KIR62637.1 - 1.7e-11 44.3 5.3 1.7e-11 44.3 5.3 4.3 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62637.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix TPR_12 PF13424.6 KIR62637.1 - 0.39 11.1 4.1 1.9 8.8 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_delta2 PF13177.6 KIR62639.1 - 7.6e-39 133.1 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 KIR62639.1 - 4.8e-16 59.0 0.3 8.2e-16 58.2 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA PF00004.29 KIR62639.1 - 1.1e-08 35.6 0.0 2.7e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIR62639.1 - 1.5e-05 24.8 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIR62639.1 - 4.9e-05 23.6 0.0 0.00025 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR62639.1 - 8.1e-05 23.1 0.5 0.002 18.5 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KIR62639.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIR62639.1 - 0.0024 17.6 0.0 0.0089 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain DciA PF05258.12 KIR62639.1 - 0.0038 17.6 0.2 0.012 16.0 0.0 1.9 2 0 0 2 2 1 1 Dna[CI] antecedent, DciA AAA_5 PF07728.14 KIR62639.1 - 0.0078 16.2 0.0 4.5 7.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KIR62639.1 - 0.038 14.0 0.0 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR62639.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI zf-CXXC PF02008.20 KIR62639.1 - 0.11 12.6 1.0 0.19 11.8 1.0 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain AAA_18 PF13238.6 KIR62639.1 - 0.18 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain YbaB_DNA_bd PF02575.16 KIR62640.1 - 1.1e-34 118.5 4.2 1.3e-34 118.3 4.2 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HrcA PF01628.21 KIR62640.1 - 0.0026 17.7 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain RTP801_C PF07809.11 KIR62640.1 - 0.088 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 RTP801 C-terminal region Toprim_4 PF13662.6 KIR62641.1 - 9.8e-25 86.8 0.0 1.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 KIR62641.1 - 4.6e-14 51.7 2.8 8.6e-14 50.8 2.8 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 KIR62641.1 - 7.9e-10 38.9 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain HHH PF00633.23 KIR62641.1 - 4.3e-06 26.3 1.5 1.2e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KIR62641.1 - 0.0027 18.3 0.1 0.014 16.0 0.0 2.2 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH_8 PF14716.6 KIR62641.1 - 0.083 13.3 0.0 0.27 11.6 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix domain SBP_bac_5 PF00496.22 KIR62642.1 - 3.3e-81 273.1 6.9 4e-81 272.9 6.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KIR62643.1 - 1.5e-40 138.9 8.7 1.5e-40 138.9 8.7 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR62644.1 - 1.5e-25 90.0 13.2 1.5e-25 90.0 13.2 2.3 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KIR62644.1 - 1.8e-15 56.7 0.6 1.8e-15 56.7 0.6 2.6 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C ABC_export PF16962.5 KIR62644.1 - 0.14 10.6 9.3 1.9 6.8 9.0 2.2 2 0 0 2 2 2 0 Putative ABC exporter ABC_tran PF00005.27 KIR62645.1 - 6.9e-27 94.6 0.0 9.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR62645.1 - 6e-18 65.1 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR62645.1 - 6.8e-08 32.7 0.2 3e-07 30.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR62645.1 - 0.0013 18.3 0.0 0.0023 17.4 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR62645.1 - 0.0014 18.9 0.2 0.0075 16.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KIR62645.1 - 0.084 12.3 0.2 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KIR62646.1 - 4.4e-29 101.7 0.0 6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR62646.1 - 1e-16 61.1 1.3 1.8e-16 60.4 0.3 1.9 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR62646.1 - 0.00078 19.3 0.2 0.57 9.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR62646.1 - 0.0019 17.7 0.0 0.031 13.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR62646.1 - 0.0032 17.8 0.2 0.0079 16.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR62646.1 - 0.01 16.2 0.2 0.016 15.6 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KIR62646.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KIR62646.1 - 0.027 14.0 0.3 2.2 7.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIR62646.1 - 0.043 13.2 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KIR62646.1 - 0.051 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KIR62646.1 - 0.057 13.8 0.1 0.12 12.8 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIR62646.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATPase PF06745.13 KIR62646.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KIR62646.1 - 0.17 11.8 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1524 PF07510.11 KIR62648.1 - 3e-09 36.9 0.0 3.6e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HMGL-like PF00682.19 KIR62649.1 - 3.5e-75 253.0 0.0 5.1e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIR62649.1 - 4.1e-29 101.2 1.2 6.7e-29 100.5 1.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 KIR62649.1 - 0.12 12.7 0.3 5.6 7.3 0.0 2.3 1 1 1 2 2 2 0 Sigma factor regulator N-terminal Nitroreductase PF00881.24 KIR62650.1 - 3.1e-16 59.9 3.2 8.3e-15 55.2 3.2 2.1 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIR62650.1 - 3.2e-05 23.6 0.0 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 Putative TM nitroreductase HEAT_2 PF13646.6 KIR62650.1 - 0.00097 19.5 1.4 0.058 13.8 0.1 2.5 2 0 0 2 2 2 2 HEAT repeats AA_kinase PF00696.28 KIR62651.1 - 4.3e-55 186.9 3.2 6.1e-55 186.4 3.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KIR62651.1 - 1.7e-19 69.2 1.0 4.8e-10 39.0 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KIR62651.1 - 6.5e-16 57.9 0.3 7.7e-13 48.0 0.0 3.0 3 0 0 3 3 3 2 ACT domain Semialdhyde_dhC PF02774.18 KIR62652.1 - 5.4e-45 153.7 0.0 7.3e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KIR62652.1 - 2.6e-27 95.6 0.0 4.3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KIR62652.1 - 0.093 12.3 0.2 0.26 10.9 0.1 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GGDEF PF00990.21 KIR62653.1 - 5.6e-29 101.0 0.0 1.4e-28 99.7 0.0 1.7 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 KIR62653.1 - 1.5e-11 44.7 7.4 1e-07 32.3 0.2 2.8 3 0 0 3 3 3 2 GAF domain GAF PF01590.26 KIR62653.1 - 3.6e-09 37.4 0.8 3.6e-07 30.9 0.2 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KIR62653.1 - 1.6e-06 28.5 0.7 0.0006 20.2 0.1 3.3 3 1 0 3 3 3 1 GAF domain GGDEF_2 PF17853.1 KIR62653.1 - 1.6e-05 25.1 5.5 2e-05 24.8 1.1 2.9 2 1 0 2 2 2 1 GGDEF-like domain Metallophos PF00149.28 KIR62654.1 - 3.4e-18 66.9 0.2 5.6e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR62654.1 - 1.8e-10 41.2 0.0 4.1e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GGDEF_2 PF17853.1 KIR62654.1 - 0.023 15.0 0.7 0.13 12.5 0.0 2.2 2 1 0 2 2 2 0 GGDEF-like domain DUF1524 PF07510.11 KIR62657.1 - 1.1e-10 41.5 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KIR62657.1 - 0.0033 17.3 0.6 0.012 15.6 0.6 1.9 1 1 0 1 1 1 1 HNH endonuclease HTH_31 PF13560.6 KIR62661.1 - 1.5e-06 28.5 0.0 1.5e-06 28.5 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62661.1 - 0.0013 18.8 0.0 0.0044 17.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix NUDIX PF00293.28 KIR62662.1 - 7.7e-21 74.5 1.7 1e-20 74.1 1.7 1.2 1 0 0 1 1 1 1 NUDIX domain Phage_integrase PF00589.22 KIR62665.1 - 1.3e-16 60.9 0.0 3.6e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KIR62665.1 - 8.7e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Metallophos PF00149.28 KIR62666.1 - 2.7e-08 34.6 0.0 3.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR62666.1 - 2.5e-07 31.0 0.0 8.2e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YqeY PF09424.10 KIR62667.1 - 1.3e-43 148.5 3.8 1.5e-43 148.3 3.8 1.0 1 0 0 1 1 1 1 Yqey-like protein FANCI_S1-cap PF14674.6 KIR62667.1 - 0.02 14.9 2.2 1.9 8.6 0.3 2.8 2 1 0 2 2 2 0 FANCI solenoid 1 cap PsaN PF05479.11 KIR62667.1 - 4.8 7.4 8.5 0.64 10.2 1.7 2.3 1 1 1 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Transgly PF00912.22 KIR62668.1 - 2.2e-58 196.7 0.0 4.9e-58 195.5 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KIR62668.1 - 2.2e-23 82.9 0.7 7.9e-23 81.1 0.7 1.9 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain PASTA PF03793.19 KIR62668.1 - 0.0035 17.2 0.2 0.012 15.4 0.1 2.1 2 0 0 2 2 2 1 PASTA domain DUF2680 PF10925.8 KIR62668.1 - 0.039 13.9 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Whib PF02467.16 KIR62669.1 - 9.8e-24 83.7 0.9 1.4e-23 83.2 0.9 1.2 1 0 0 1 1 1 1 Transcription factor WhiB DUF1289 PF06945.13 KIR62669.1 - 0.021 14.6 1.2 0.29 10.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) DUF2800 PF10926.8 KIR62669.1 - 0.038 13.2 0.2 0.044 13.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) ArsA_ATPase PF02374.15 KIR62670.1 - 2.6e-23 82.7 0.0 1.6e-22 80.1 0.0 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KIR62670.1 - 1.5e-09 38.0 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIR62670.1 - 7.2e-09 35.8 0.0 2.1e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KIR62670.1 - 5.8e-06 25.9 0.7 0.00075 19.0 0.7 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KIR62670.1 - 9.5e-05 22.1 0.0 0.00043 20.0 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIR62670.1 - 0.00057 20.2 0.2 0.0015 18.8 0.2 1.9 2 1 0 2 2 1 1 AAA domain AAA_26 PF13500.6 KIR62670.1 - 0.00097 19.0 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KIR62670.1 - 0.0013 18.2 0.1 0.0027 17.2 0.0 1.5 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 KIR62670.1 - 0.002 18.4 0.5 0.0064 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIR62670.1 - 0.0026 17.5 0.2 0.0026 17.5 0.2 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR62670.1 - 0.0042 17.3 0.6 0.011 15.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIR62670.1 - 0.008 15.8 3.2 0.008 15.8 3.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR62670.1 - 0.015 15.7 0.3 0.015 15.7 0.3 2.2 2 2 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KIR62670.1 - 0.018 14.1 0.1 0.038 13.0 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KIR62670.1 - 0.022 14.5 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Methyltransf_24 PF13578.6 KIR62670.1 - 0.023 15.7 2.7 0.65 11.1 0.1 3.2 2 2 0 2 2 2 0 Methyltransferase domain ATPase PF06745.13 KIR62670.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 KaiC Fer4_NifH PF00142.18 KIR62670.1 - 0.074 12.5 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ResIII PF04851.15 KIR62670.1 - 0.082 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1290 PF06947.12 KIR62670.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Orbi_VP6 PF01516.16 KIR62670.1 - 0.14 11.6 0.2 2.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Orbivirus helicase VP6 MipZ PF09140.11 KIR62670.1 - 0.16 11.2 0.4 5.2 6.3 0.2 2.3 1 1 0 2 2 2 0 ATPase MipZ CobA_CobO_BtuR PF02572.15 KIR62670.1 - 0.28 11.4 1.6 0.93 9.7 1.6 1.9 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YjeF_N PF03853.15 KIR62670.1 - 0.47 10.3 2.9 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus ArsA_ATPase PF02374.15 KIR62671.1 - 2.4e-21 76.2 0.0 1.2e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 KIR62671.1 - 5.4e-08 32.9 0.0 9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KIR62671.1 - 4.2e-07 30.0 0.1 6.1e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 KIR62671.1 - 1.2e-05 24.9 0.3 2.8e-05 23.7 0.0 1.7 3 0 0 3 3 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KIR62671.1 - 0.0014 18.1 0.1 0.0026 17.3 0.1 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KIR62671.1 - 0.002 17.8 0.3 0.002 17.8 0.3 2.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KIR62671.1 - 0.0036 17.0 0.6 0.0095 15.7 0.6 1.7 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KIR62671.1 - 0.0071 15.7 0.0 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ IstB_IS21 PF01695.17 KIR62671.1 - 0.013 15.2 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KIR62671.1 - 0.021 15.2 4.0 0.048 14.0 4.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KIR62671.1 - 0.033 14.0 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR62671.1 - 0.042 14.4 0.0 0.066 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIR62671.1 - 0.043 13.3 0.2 0.075 12.5 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KIR62671.1 - 0.056 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 KIR62671.1 - 0.058 12.8 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.12 KIR62671.1 - 0.1 12.5 0.2 0.35 10.8 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Zot PF05707.12 KIR62671.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF2075 PF09848.9 KIR62671.1 - 0.12 11.5 0.2 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SMC_N PF02463.19 KIR62671.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KIR62671.1 - 0.18 11.5 0.1 0.27 10.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 KIR62671.1 - 0.37 10.1 1.4 0.33 10.2 0.2 1.5 2 0 0 2 2 2 0 VirC1 protein DUF4878 PF12870.7 KIR62672.1 - 0.00043 20.6 0.2 0.00059 20.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) MecA_N PF05223.11 KIR62672.1 - 0.12 12.6 0.2 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Lactamase_B PF00753.27 KIR62674.1 - 1.9e-13 50.9 11.7 5.2e-13 49.4 11.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR62674.1 - 6.7e-08 32.3 2.9 6.9e-07 29.0 2.8 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KIR62674.1 - 8.9e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 KIR62674.1 - 0.00026 20.9 0.0 0.00049 20.0 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Guanylate_cyc PF00211.20 KIR62675.1 - 6.6e-24 84.5 0.0 9.5e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 KIR62675.1 - 3.9e-14 53.4 1.3 3.9e-14 53.4 1.3 3.8 3 1 1 4 4 4 1 AAA ATPase domain TPR_MalT PF17874.1 KIR62675.1 - 3.1e-13 49.8 27.1 8.7e-08 31.9 12.2 3.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_12 PF13424.6 KIR62675.1 - 2.3e-11 43.8 47.5 0.0061 16.8 3.3 8.1 6 2 1 7 7 7 5 Tetratricopeptide repeat DZR PF12773.7 KIR62675.1 - 0.00014 21.8 0.1 0.00028 20.8 0.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KIR62675.1 - 0.00017 21.2 2.0 0.00029 20.4 2.0 1.4 1 0 0 1 1 1 1 zinc-ribbon domain TPR_2 PF07719.17 KIR62675.1 - 0.0004 20.3 32.5 0.27 11.4 0.3 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 KIR62675.1 - 0.00061 19.1 2.6 0.0012 18.1 2.6 1.5 1 0 0 1 1 1 1 zinc-ribbon domain AAA_22 PF13401.6 KIR62675.1 - 0.00065 20.0 0.0 0.0055 17.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain TPR_4 PF07721.14 KIR62675.1 - 0.0039 17.7 2.9 0.0039 17.7 2.9 13.7 11 0 0 11 11 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIR62675.1 - 0.027 14.7 1.9 5.3 7.3 0.0 3.6 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIR62675.1 - 0.037 13.9 7.8 2.6 8.0 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_ParB PF17762.1 KIR62675.1 - 0.12 12.2 0.1 0.41 10.5 0.1 1.9 1 0 0 1 1 1 0 HTH domain found in ParB protein TPR_8 PF13181.6 KIR62675.1 - 0.36 11.1 8.1 2.2 8.7 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KIR62675.1 - 0.54 10.4 2.0 36 4.5 0.8 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF4267 PF14087.6 KIR62676.1 - 0.096 12.8 5.1 0.15 12.1 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) Pkinase PF00069.25 KIR62677.1 - 2.9e-40 138.3 0.0 3.6e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR62677.1 - 1.4e-23 83.5 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR62677.1 - 0.00011 22.2 4.5 0.0051 16.8 0.4 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family SPDY PF03771.16 KIR62677.1 - 0.0041 17.0 0.4 0.0041 17.0 0.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF317) VirB8 PF04335.13 KIR62677.1 - 0.079 12.8 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 VirB8 protein Kinase-like PF14531.6 KIR62677.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 2 0 0 2 2 2 0 Kinase-like ABC1 PF03109.16 KIR62677.1 - 0.16 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Abhydrolase_1 PF00561.20 KIR62678.1 - 6.3e-30 104.7 0.0 1.6e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIR62678.1 - 1.6e-21 76.4 0.1 4.9e-21 74.8 0.1 1.9 1 0 0 1 1 1 1 TAP-like protein SBP_bac_3 PF00497.20 KIR62679.1 - 1.5e-37 129.2 0.0 1.9e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 KIR62679.1 - 0.014 15.6 0.0 0.064 13.5 0.0 1.9 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Lactamase_B PF00753.27 KIR62681.1 - 3.4e-10 40.3 5.9 5.4e-10 39.6 5.9 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR62681.1 - 0.00016 21.2 0.1 0.00022 20.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIR62681.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TRAM_2 PF18693.1 KIR62681.1 - 0.03 14.5 0.2 0.069 13.3 0.2 1.6 1 0 0 1 1 1 0 TRAM domain Acyl-CoA_dh_1 PF00441.24 KIR62682.1 - 1.8e-28 99.7 6.0 2.5e-28 99.2 6.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR62682.1 - 2.3e-26 92.7 0.2 2.3e-26 92.7 0.2 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIR62682.1 - 2.7e-18 65.9 0.0 5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIR62682.1 - 1e-06 29.0 9.9 1.7e-06 28.3 9.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vault PF01505.18 KIR62682.1 - 0.095 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain CPSase_L_D2 PF02786.17 KIR62683.1 - 7.1e-65 218.5 0.0 1.2e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIR62683.1 - 1.5e-40 138.1 0.0 3.3e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIR62683.1 - 2.5e-30 104.8 0.0 1.2e-29 102.6 0.0 2.3 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIR62683.1 - 9.8e-16 57.4 0.2 5.4e-15 55.0 0.0 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KIR62683.1 - 2.8e-13 49.9 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KIR62683.1 - 8.1e-11 41.6 0.8 1e-06 28.5 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KIR62683.1 - 7.7e-08 32.1 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KIR62683.1 - 4.1e-06 27.4 1.2 0.082 13.6 0.5 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 KIR62683.1 - 0.00062 19.0 0.2 0.66 9.2 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KIR62683.1 - 0.00094 19.1 0.3 0.93 9.5 0.1 3.3 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain ATP-grasp_4 PF13535.6 KIR62683.1 - 0.054 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Carboxyl_trans PF01039.22 KIR62684.1 - 4.2e-131 438.0 0.0 5.1e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 KIR62684.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase AtuA PF07287.11 KIR62685.1 - 8.8e-122 406.2 0.0 1.3e-121 405.6 0.0 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA TetR_N PF00440.23 KIR62686.1 - 6.4e-11 41.9 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF4510 PF14971.6 KIR62686.1 - 0.11 12.9 6.0 0.07 13.5 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) GvpG PF05120.12 KIR62687.1 - 1.9 8.6 6.1 36 4.5 1.1 3.3 1 1 2 3 3 3 0 Gas vesicle protein G Metallophos_2 PF12850.7 KIR62688.1 - 3.2e-23 82.7 0.0 4.8e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIR62688.1 - 2.8e-08 34.5 0.0 3e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KIR62688.1 - 0.015 14.6 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily cNMP_binding PF00027.29 KIR62689.1 - 9e-26 89.8 0.0 1.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 KIR62689.1 - 1.8e-18 66.2 1.7 3.4e-18 65.4 0.3 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 KIR62689.1 - 4.3e-05 23.1 0.0 0.00013 21.6 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family GntR PF00392.21 KIR62689.1 - 7.9e-05 22.2 0.0 0.00024 20.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 KIR62689.1 - 0.00016 21.1 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 KIR62689.1 - 0.00017 21.4 0.2 0.00064 19.6 0.2 2.1 1 1 0 1 1 1 1 MarR family Sigma70_r4_2 PF08281.12 KIR62689.1 - 0.0024 17.5 0.1 0.0073 16.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR62689.1 - 0.0024 17.4 0.3 0.0066 16.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KIR62689.1 - 0.0026 17.5 1.1 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_36 PF13730.6 KIR62689.1 - 0.0044 16.9 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KIR62689.1 - 0.0053 16.9 0.5 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR62689.1 - 0.0056 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_3 PF01381.22 KIR62689.1 - 0.023 14.8 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix DUF977 PF06163.11 KIR62689.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_IclR PF09339.10 KIR62689.1 - 0.044 13.6 1.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HemN_C PF06969.16 KIR62689.1 - 0.071 13.2 0.0 0.38 10.9 0.0 2.2 1 1 1 2 2 2 0 HemN C-terminal domain HTH_31 PF13560.6 KIR62689.1 - 0.079 13.3 3.7 0.28 11.5 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain TraI_2 PF07514.11 KIR62689.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative helicase TrmB PF01978.19 KIR62689.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TetR PF13972.6 KIR62689.1 - 0.17 11.6 0.1 10 5.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial transcriptional repressor CbiZ PF01955.18 KIR62690.1 - 1.1e-48 166.0 2.8 1.2e-48 165.8 2.8 1.0 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase FAM25 PF15825.5 KIR62690.1 - 0.094 13.1 0.7 0.094 13.1 0.7 1.6 2 0 0 2 2 2 0 FAM25 family HhH-GPD PF00730.25 KIR62691.1 - 3.8e-23 82.0 0.0 6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIR62691.1 - 2.3e-07 30.3 0.4 6.2e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KIR62691.1 - 0.0043 17.4 4.9 0.0083 16.4 4.9 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 KIR62691.1 - 0.19 12.4 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Redoxin PF08534.10 KIR62692.1 - 4.5e-18 65.4 0.0 6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIR62692.1 - 2.2e-17 63.1 0.0 2.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 KIR62692.1 - 3.9e-07 30.0 0.0 6.8e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIR62692.1 - 5.2e-07 29.9 0.0 7.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like T4_deiodinase PF00837.17 KIR62692.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase NUDIX PF00293.28 KIR62693.1 - 7.6e-12 45.4 0.3 1.2e-11 44.8 0.3 1.3 1 0 0 1 1 1 1 NUDIX domain Leu_leader PF08054.11 KIR62693.1 - 0.16 11.6 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Leucine operon leader peptide Trypsin_2 PF13365.6 KIR62694.1 - 2.4e-21 77.2 1.8 2.4e-21 77.2 1.8 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Colicin_V PF02674.16 KIR62694.1 - 1.9e-18 66.8 15.9 3.3e-18 66.0 15.9 1.3 1 0 0 1 1 1 1 Colicin V production protein Trypsin PF00089.26 KIR62694.1 - 3.1e-08 33.7 0.0 5.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S29 PF02907.15 KIR62694.1 - 0.043 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease T4SS_CagC PF16943.5 KIR62694.1 - 0.081 13.1 0.8 15 5.8 0.3 2.6 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system PAP2 PF01569.21 KIR62695.1 - 3.3e-16 59.3 10.9 3.3e-16 59.3 10.9 2.6 1 1 2 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 KIR62695.1 - 0.067 12.9 24.9 1.7 8.3 24.9 3.0 1 1 0 1 1 1 0 PAP2 superfamily TMEM208_SND2 PF05620.11 KIR62695.1 - 0.17 11.7 4.1 0.55 10.0 1.1 2.2 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2427 PF10348.9 KIR62695.1 - 0.36 10.6 9.6 4.6 7.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Phage_holin_2_4 PF16082.5 KIR62695.1 - 0.45 10.3 0.0 0.45 10.3 0.0 2.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like PLDc_N PF13396.6 KIR62695.1 - 3.6 7.6 9.1 0.38 10.7 3.8 2.2 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal Peptidase_S8 PF00082.22 KIR62696.1 - 3.5e-40 138.1 2.4 2.1e-39 135.5 2.4 1.9 1 1 0 1 1 1 1 Subtilase family FtsK_SpoIIIE PF01580.18 KIR62697.1 - 6.8e-91 304.0 0.0 1e-48 165.8 0.0 4.7 3 1 1 4 4 4 4 FtsK/SpoIIIE family AAA_16 PF13191.6 KIR62697.1 - 3.8e-08 33.9 5.7 0.0085 16.5 0.3 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KIR62697.1 - 1e-07 32.3 0.0 0.0031 17.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KIR62697.1 - 3.2e-06 27.1 0.0 0.035 14.0 0.0 4.1 5 0 0 5 5 4 1 NACHT domain DUF87 PF01935.17 KIR62697.1 - 1.2e-05 25.5 0.1 0.043 13.9 0.0 2.6 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_29 PF13555.6 KIR62697.1 - 1.4e-05 24.7 1.2 0.35 10.7 0.1 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIR62697.1 - 1.5e-05 25.0 0.0 1 9.4 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KIR62697.1 - 0.00051 19.7 0.6 2.9 7.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KIR62697.1 - 0.00093 19.6 0.0 1.8 9.0 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Adeno_IVa2 PF02456.15 KIR62697.1 - 0.0014 17.5 0.0 2.1 7.1 0.0 3.1 3 0 0 3 3 3 1 Adenovirus IVa2 protein AAA_19 PF13245.6 KIR62697.1 - 0.0021 18.4 0.0 1.6 9.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KIR62697.1 - 0.0028 18.1 0.8 3.1 8.3 0.3 3.2 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 KIR62697.1 - 0.0056 17.2 0.1 1.1 9.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KIR62697.1 - 0.0098 15.6 0.0 4.2 7.0 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.13 KIR62697.1 - 0.012 14.8 1.4 4.5 6.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 KIR62697.1 - 0.017 15.2 0.5 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Dynamin family TrwB_AAD_bind PF10412.9 KIR62697.1 - 0.026 13.4 0.2 0.19 10.6 0.0 2.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 KIR62697.1 - 0.058 13.6 0.1 13 6.1 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KIR62697.1 - 0.14 12.7 0.0 18 5.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF853 PF05872.12 KIR62697.1 - 0.2 10.2 0.1 0.48 8.9 0.1 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_21 PF13304.6 KIR62697.1 - 0.22 11.3 0.1 1.5 8.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KIR62697.1 - 0.28 11.1 0.0 25 4.7 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea YukD PF08817.10 KIR62698.1 - 2.3e-23 82.7 2.1 7.7e-23 81.0 2.1 2.0 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Pyrophosphatase PF00719.19 KIR62699.1 - 1.5e-51 174.4 0.0 1.7e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 KIR62699.1 - 0.0077 15.9 0.0 0.018 14.8 0.0 1.7 1 1 0 1 1 1 1 Inorganic Pyrophosphatase Peptidase_S13 PF02113.15 KIR62700.1 - 3.1e-74 250.3 0.6 8.5e-46 156.6 0.3 2.1 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.20 KIR62700.1 - 0.0029 17.1 0.1 0.0065 15.9 0.0 1.5 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KIR62700.1 - 0.03 13.9 0.7 14 5.2 0.2 3.0 3 0 0 3 3 3 0 Beta-lactamase enzyme family Zincin_2 PF10103.9 KIR62701.1 - 5.6e-112 374.3 0.5 6.3e-112 374.1 0.5 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase ATP_bind_3 PF01171.20 KIR62702.1 - 3.2e-42 144.3 0.0 4.8e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family TilS PF09179.11 KIR62702.1 - 3.4e-12 46.7 3.5 3.4e-12 46.7 3.5 2.9 3 1 0 3 3 3 1 TilS substrate binding domain Ail_Lom PF06316.11 KIR62702.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein HTH_18 PF12833.7 KIR62703.1 - 1e-22 80.2 2.7 1.8e-22 79.4 2.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 KIR62703.1 - 1.5e-19 70.4 0.0 2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 KIR62703.1 - 2e-18 66.0 0.0 1.9e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DprA_WH PF17782.1 KIR62703.1 - 0.0013 18.8 4.1 0.0097 16.0 0.3 2.9 3 0 0 3 3 3 1 DprA winged helix domain TetR_N PF00440.23 KIR62703.1 - 0.0027 17.5 0.3 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 KIR62703.1 - 0.0067 16.5 0.3 0.068 13.2 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR62703.1 - 0.066 13.2 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KIR62703.1 - 0.15 12.0 4.1 0.51 10.3 0.0 3.4 3 1 0 3 3 3 0 MarR family Pribosyltran PF00156.27 KIR62704.1 - 5.5e-22 78.0 0.1 6.8e-22 77.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain THF_DHG_CYH_C PF02882.19 KIR62704.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GTP_cyclohydroI PF01227.22 KIR62705.1 - 1.7e-76 255.7 0.0 2e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I Peptidase_M23 PF01551.22 KIR62708.1 - 1.3e-21 76.6 0.3 3.5e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M23 Wzy_C_2 PF11846.8 KIR62710.1 - 4.6 7.1 8.6 7.1 6.5 0.1 3.0 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal PRRSV_2b PF07069.11 KIR62710.1 - 7.8 7.1 11.6 0.27 11.8 0.7 2.7 3 0 0 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b AAA_10 PF12846.7 KIR62711.1 - 1e-27 97.0 0.0 5.7e-26 91.3 0.0 2.1 1 1 0 1 1 1 1 AAA-like domain MeaB PF03308.16 KIR62711.1 - 0.022 13.7 0.2 0.13 11.2 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KIR62711.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIR62711.1 - 0.15 11.8 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.23 KIR62711.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pterin_bind PF00809.22 KIR62714.1 - 2.7e-85 285.9 0.1 3.1e-85 285.7 0.1 1.0 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KIR62715.1 - 1.2e-32 112.8 0.0 1.4e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glucos_trans_II PF14264.6 KIR62716.1 - 2.3 7.5 6.6 0.26 10.6 0.1 2.2 2 1 0 2 2 2 0 Glucosyl transferase GtrII ABC_tran PF00005.27 KIR62719.1 - 1.7e-32 112.8 0.0 2.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR62719.1 - 1.4e-08 35.0 0.1 0.0034 17.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR62719.1 - 9e-07 29.4 0.1 2.9e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KIR62719.1 - 0.0024 17.4 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIR62719.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR62719.1 - 0.0027 17.6 0.0 0.0062 16.4 0.0 1.5 2 0 0 2 2 1 1 RsgA GTPase Rad17 PF03215.15 KIR62719.1 - 0.0032 17.4 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 KIR62719.1 - 0.0035 17.3 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIR62719.1 - 0.0037 17.7 0.0 0.039 14.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIR62719.1 - 0.004 17.4 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR62719.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIR62719.1 - 0.0063 16.3 0.0 0.0089 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIR62719.1 - 0.013 15.7 0.1 0.029 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIR62719.1 - 0.051 13.8 0.6 0.18 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KIR62719.1 - 0.088 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIR62719.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR62719.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIR62719.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 1 0 NACHT domain Adeno_IVa2 PF02456.15 KIR62719.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 KIR62719.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 KIR62719.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 KIR62719.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SMC_N PF02463.19 KIR62719.1 - 0.2 11.1 0.0 4 6.8 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KIR62719.1 - 0.22 11.2 0.1 0.85 9.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KIR62719.1 - 0.25 11.1 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family BPD_transp_1 PF00528.22 KIR62720.1 - 1.5e-20 73.7 17.2 1.9e-20 73.4 17.2 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OpuAC PF04069.12 KIR62721.1 - 3e-39 135.2 9.0 8.2e-30 104.2 0.4 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Complex1_49kDa PF00346.19 KIR62722.1 - 3.3e-71 239.5 0.0 1.3e-49 168.8 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KIR62722.1 - 0.023 13.6 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Methyltransf_28 PF02636.17 KIR62723.1 - 2.3e-20 73.4 0.0 8.5e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Phytase PF02333.15 KIR62724.1 - 5.8e-38 130.8 0.0 3.3e-23 82.3 0.0 3.0 2 1 1 3 3 3 3 Phytase DUF2520 PF10728.9 KIR62725.1 - 1.1e-37 128.6 0.4 1.1e-37 128.6 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2520) Rossmann-like PF10727.9 KIR62725.1 - 3.2e-34 117.6 12.9 3.2e-34 117.6 12.9 1.7 2 0 0 2 2 2 1 Rossmann-like domain F420_oxidored PF03807.17 KIR62725.1 - 1.4e-05 25.6 1.7 3.6e-05 24.3 1.7 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIR62725.1 - 0.0014 18.8 1.0 0.012 15.8 0.4 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KIR62725.1 - 0.023 14.6 1.0 0.072 13.0 1.4 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR62725.1 - 0.074 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIR62725.1 - 0.079 12.5 2.3 0.14 11.7 2.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HTH_17 PF12728.7 KIR62725.1 - 0.14 12.3 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_14 PF13428.6 KIR62725.1 - 0.15 13.0 0.5 0.15 13.0 0.5 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat ApbA PF02558.16 KIR62725.1 - 0.23 11.1 8.7 0.47 10.1 5.3 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KIR62725.1 - 0.24 11.7 1.8 0.79 10.0 1.8 1.9 1 1 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 KIR62725.1 - 2.4 8.1 4.2 22 5.0 2.9 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pantoate_ligase PF02569.15 KIR62726.1 - 4.7e-91 304.7 0.0 5.8e-91 304.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 KIR62726.1 - 0.0056 16.2 0.1 0.0088 15.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase FAD_syn PF06574.12 KIR62726.1 - 0.037 13.9 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD synthetase Asp_decarbox PF02261.16 KIR62727.1 - 3.3e-52 175.3 0.0 3.9e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 Aspartate decarboxylase Septum_form PF13845.6 KIR62728.1 - 6.8e-49 166.4 0.1 8e-49 166.2 0.1 1.1 1 0 0 1 1 1 1 Septum formation FAD_binding_2 PF00890.24 KIR62729.1 - 3.9e-90 302.9 18.0 3.9e-90 302.9 18.0 1.6 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIR62729.1 - 1.3e-12 47.8 0.7 1.3e-10 41.4 0.7 2.3 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KIR62729.1 - 2.3e-12 46.7 5.6 8.4e-06 25.2 0.2 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR62729.1 - 2.4e-12 47.1 12.8 9.2e-11 41.9 6.4 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIR62729.1 - 8.4e-06 25.3 0.5 1.3e-05 24.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIR62729.1 - 0.00038 20.6 0.7 0.00038 20.6 0.7 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIR62729.1 - 0.00045 19.5 0.4 0.00045 19.5 0.4 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 KIR62729.1 - 0.0016 17.2 4.3 0.0051 15.6 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 KIR62729.1 - 0.0016 18.8 0.2 0.0037 17.7 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KIR62729.1 - 0.0034 16.7 0.3 0.0078 15.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR62729.1 - 0.0036 16.4 1.3 0.0036 16.4 1.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIR62729.1 - 0.0052 15.9 0.2 0.011 14.9 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KIR62729.1 - 0.0076 15.6 0.8 0.016 14.5 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIR62729.1 - 0.011 15.1 1.7 0.021 14.2 1.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR62729.1 - 0.032 14.8 1.3 0.032 14.8 1.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 KIR62729.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Trp_halogenase PF04820.14 KIR62729.1 - 0.14 11.0 0.6 0.21 10.4 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase QRPTase_C PF01729.19 KIR62730.1 - 1.3e-55 187.8 0.4 1.8e-55 187.3 0.4 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KIR62730.1 - 1e-22 79.9 5.2 7.4e-22 77.2 2.2 2.9 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 KIR62730.1 - 0.083 12.7 0.1 0.083 12.7 0.1 2.5 4 0 0 4 4 4 0 Biotin-lipoyl like Pan_kinase PF03309.14 KIR62731.1 - 1.6e-64 217.6 0.0 1.9e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase CK2S PF15011.6 KIR62731.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate tRNA-synt_2 PF00152.20 KIR62732.1 - 1.4e-67 228.0 0.0 1.8e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIR62732.1 - 1.1e-12 47.7 0.2 2e-12 46.9 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIR62732.1 - 0.00089 18.8 0.2 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pyridox_ox_2 PF12900.7 KIR62732.1 - 0.018 15.0 0.2 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase tRNA_anti_2 PF13742.6 KIR62732.1 - 0.02 15.1 0.0 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Lsr2 PF11774.8 KIR62733.1 - 2.2e-38 130.8 0.2 2.4e-38 130.7 0.2 1.0 1 0 0 1 1 1 1 Lsr2 AAA_2 PF07724.14 KIR62734.1 - 6.6e-54 182.6 0.0 7.2e-52 175.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 KIR62734.1 - 1.5e-36 124.3 8.4 1.9e-18 66.3 1.2 2.7 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 KIR62734.1 - 3.3e-35 120.1 1.3 9.2e-35 118.7 1.3 1.8 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 KIR62734.1 - 7.8e-26 89.9 0.3 3.5e-25 87.9 0.3 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIR62734.1 - 1.1e-22 80.8 0.0 3.4e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIR62734.1 - 2.6e-18 66.4 0.0 1.2e-11 44.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIR62734.1 - 5.1e-12 46.5 5.4 4.9e-06 27.0 1.6 4.4 2 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KIR62734.1 - 3e-10 40.5 0.8 0.0011 19.3 0.1 4.5 2 2 1 3 3 2 2 AAA domain TniB PF05621.11 KIR62734.1 - 2e-09 37.1 0.2 1.6e-06 27.7 0.1 3.7 2 2 0 2 2 2 1 Bacterial TniB protein UVR PF02151.19 KIR62734.1 - 3.7e-08 32.9 4.4 9.8e-08 31.5 4.4 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Sigma54_activat PF00158.26 KIR62734.1 - 6.2e-08 32.5 0.1 0.00017 21.4 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 KIR62734.1 - 4.4e-06 27.3 4.1 0.014 16.0 0.0 4.1 4 1 1 5 5 4 2 AAA domain IstB_IS21 PF01695.17 KIR62734.1 - 1.7e-05 24.7 0.1 0.13 12.0 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KIR62734.1 - 2.2e-05 24.5 3.0 0.053 13.4 0.1 3.9 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KIR62734.1 - 6.9e-05 22.6 0.1 2.8 7.7 0.0 4.4 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 KIR62734.1 - 0.00011 22.2 0.1 0.57 10.1 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KIR62734.1 - 0.00015 21.8 0.0 0.21 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR62734.1 - 0.00022 21.4 1.0 1.1 9.5 0.0 4.2 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KIR62734.1 - 0.00027 21.3 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 KIR62734.1 - 0.00034 19.9 0.1 3 6.9 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KIR62734.1 - 0.00079 19.2 0.1 0.52 10.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KIR62734.1 - 0.00082 19.2 0.0 0.28 11.0 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIR62734.1 - 0.0014 18.6 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIR62734.1 - 0.0017 17.8 0.0 5.2 6.4 0.0 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KIR62734.1 - 0.0029 17.1 0.0 1 8.8 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_28 PF13521.6 KIR62734.1 - 0.005 17.1 0.6 3.8 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KIR62734.1 - 0.0054 16.7 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DNA_pol3_delta2 PF13177.6 KIR62734.1 - 0.0066 16.2 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Roc PF08477.13 KIR62734.1 - 0.0082 16.4 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 KIR62734.1 - 0.011 15.8 0.0 2.6 8.0 0.0 3.6 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIR62734.1 - 0.015 15.7 0.0 0.6 10.4 0.1 3.2 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.27 KIR62734.1 - 0.017 15.7 0.0 4.2 7.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KIR62734.1 - 0.021 14.6 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIR62734.1 - 0.024 14.5 0.2 12 5.8 0.1 3.4 3 0 0 3 3 3 0 NTPase TIP49 PF06068.13 KIR62734.1 - 0.026 13.7 0.2 8.8 5.4 0.0 2.7 3 0 0 3 3 2 0 TIP49 P-loop domain Zeta_toxin PF06414.12 KIR62734.1 - 0.028 13.7 0.0 2.8 7.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KIR62734.1 - 0.035 13.7 0.1 13 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Torsin PF06309.11 KIR62734.1 - 0.081 13.0 0.0 1 9.5 0.0 2.6 3 0 0 3 3 3 0 Torsin AAA_23 PF13476.6 KIR62734.1 - 0.92 10.0 4.1 4 7.9 0.3 3.3 3 1 0 3 3 3 0 AAA domain ACT_6 PF13740.6 KIR62735.1 - 1.7e-20 72.8 1.0 7e-11 42.0 0.2 2.1 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KIR62735.1 - 2.1e-14 52.9 3.2 2e-06 27.5 0.1 2.6 2 1 1 3 3 3 2 ACT domain ACT_4 PF13291.6 KIR62735.1 - 7.1e-11 42.6 0.0 6.9e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KIR62735.1 - 2.1e-06 27.4 0.2 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 ACT domain Pep_deformylase PF01327.21 KIR62736.1 - 3.4e-35 121.0 0.0 4e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase ATPase PF06745.13 KIR62737.1 - 1.8e-15 56.9 0.0 1.5e-10 40.9 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 KIR62737.1 - 1.2e-13 51.1 6.8 2.9e-13 49.8 4.0 2.6 2 1 0 2 2 2 1 AAA domain Rubredoxin_2 PF18073.1 KIR62737.1 - 1e-11 44.4 5.9 1.7e-11 43.6 5.9 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain DnaB_C PF03796.15 KIR62737.1 - 1.3e-08 34.5 0.0 6e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ChlI PF13541.6 KIR62737.1 - 1.4e-05 24.9 0.3 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA PF00004.29 KIR62737.1 - 4.5e-05 23.9 0.0 7.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIR62737.1 - 0.00035 21.0 0.4 0.00035 21.0 0.4 2.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIR62737.1 - 0.00039 20.4 0.1 0.00071 19.5 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KIR62737.1 - 0.0011 19.3 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.11 KIR62737.1 - 0.0021 17.4 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Rad51 AAA_30 PF13604.6 KIR62737.1 - 0.0042 16.8 4.2 0.023 14.4 4.2 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIR62737.1 - 0.018 15.6 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIR62737.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lon_C PF05362.13 KIR62737.1 - 0.037 13.6 0.2 0.037 13.6 0.2 2.2 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 KIR62737.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KIR62737.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 1 0 NTPase RsgA_GTPase PF03193.16 KIR62737.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KIR62737.1 - 0.16 11.2 0.1 0.3 10.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KIR62737.1 - 0.16 11.7 0.0 0.38 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain PAXNEB PF05625.11 KIR62737.1 - 0.24 10.5 0.1 0.44 9.6 0.1 1.3 1 0 0 1 1 1 0 PAXNEB protein Zn-ribbon_8 PF09723.10 KIR62737.1 - 1.6 8.9 4.7 4.6 7.4 4.7 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KIR62737.1 - 5.9 6.4 7.3 43 3.7 7.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain UbiA PF01040.18 KIR62738.1 - 3.2e-26 92.2 30.2 3.9e-26 91.9 30.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_11 PF08241.12 KIR62739.1 - 3.1e-21 75.8 0.1 6.1e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR62739.1 - 6.8e-16 58.8 0.2 1.1e-15 58.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR62739.1 - 1e-14 54.7 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR62739.1 - 3.2e-11 43.2 0.0 4.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62739.1 - 7.2e-11 42.7 0.0 1.3e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIR62739.1 - 2.6e-05 24.2 0.0 3.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KIR62739.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 KIR62739.1 - 0.0049 17.2 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 KIR62739.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KIR62739.1 - 0.017 14.6 0.2 0.053 13.1 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KIR62739.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FtsJ PF01728.19 KIR62739.1 - 0.21 11.7 0.0 20 5.2 0.0 2.1 1 1 1 2 2 2 0 FtsJ-like methyltransferase TPMT PF05724.11 KIR62739.1 - 0.23 11.1 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Cuticle_1 PF08140.11 KIR62740.1 - 0.0084 16.1 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 Crustacean cuticle protein repeat CarD_CdnL_TRCF PF02559.16 KIR62742.1 - 8.9e-17 61.6 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 CarD-like/TRCF domain IspD PF01128.19 KIR62743.1 - 3.3e-64 216.7 5.1 3.7e-64 216.5 5.1 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 KIR62743.1 - 1.1e-11 45.3 14.1 2.1e-11 44.4 13.6 1.6 1 1 1 2 2 2 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 KIR62743.1 - 0.0019 18.1 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase YgbB PF02542.16 KIR62744.1 - 3.1e-45 154.2 0.0 3.5e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 YgbB family TPR_2 PF07719.17 KIR62745.1 - 3.6e-14 51.7 26.8 3e-05 23.8 0.6 4.8 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIR62745.1 - 5.2e-12 45.0 10.9 0.00041 20.0 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIR62745.1 - 1.9e-11 43.2 4.3 0.026 14.7 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIR62745.1 - 1.1e-10 42.0 62.3 8.2e-06 26.4 19.3 4.9 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIR62745.1 - 1e-08 35.3 49.0 0.00053 20.6 6.0 6.0 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIR62745.1 - 1.9e-06 27.9 9.7 0.0038 17.5 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIR62745.1 - 4.2e-06 27.2 8.7 4.2e-06 27.2 8.7 4.1 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIR62745.1 - 9.9e-06 25.8 25.0 0.01 16.1 9.4 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIR62745.1 - 2.5e-05 23.8 10.2 0.057 13.1 0.4 3.9 2 1 2 4 4 4 3 TPR repeat TPR_9 PF13371.6 KIR62745.1 - 9.2e-05 22.5 40.8 0.0055 16.8 12.0 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIR62745.1 - 0.00048 20.0 18.5 3.3 7.9 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KIR62745.1 - 0.0024 18.1 5.9 0.0058 16.8 0.3 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KIR62745.1 - 0.008 16.7 8.2 0.008 16.7 8.2 7.6 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIR62745.1 - 0.013 15.3 3.1 0.013 15.3 3.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIR62745.1 - 0.055 13.6 6.6 2.6 8.2 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 KIR62745.1 - 0.16 11.6 6.3 0.25 11.0 5.5 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 KIR62745.1 - 2 9.3 19.6 0.84 10.4 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NmrA PF05368.13 KIR62747.1 - 4.2e-19 69.0 0.0 5.6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIR62747.1 - 2.4e-17 63.4 4.4 3.8e-17 62.8 4.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KIR62747.1 - 5.5e-05 22.7 0.1 9.7e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KIR62747.1 - 0.015 14.8 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR62747.1 - 0.044 12.9 0.1 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 KIR62747.1 - 0.13 12.1 1.8 0.26 11.2 1.8 1.7 1 1 0 1 1 1 0 KR domain HgmA PF04209.13 KIR62748.1 - 5.7e-14 51.6 0.0 1.2e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Cupin_2 PF07883.11 KIR62748.1 - 1.6e-06 27.7 0.0 7.2e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Cupin domain DUF2603 PF10788.9 KIR62748.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FAA_hydrolase PF01557.18 KIR62750.1 - 4.1e-53 180.3 0.0 5.5e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KIR62750.1 - 1.6e-21 76.5 0.0 2.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Polyketide_cyc2 PF10604.9 KIR62751.1 - 7.6e-09 36.0 5.8 8.6e-09 35.8 5.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIR62751.1 - 0.00043 20.5 0.1 0.00053 20.2 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 KIR62751.1 - 0.0036 17.5 0.1 0.0045 17.2 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Trp_oprn_chp PF09534.10 KIR62751.1 - 0.11 12.3 8.5 0.041 13.7 5.7 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PQQ_2 PF13360.6 KIR62752.1 - 1.7e-15 57.3 26.2 3.8e-07 30.0 8.7 3.2 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 KIR62752.1 - 1.6e-11 43.6 0.8 0.0016 18.3 0.1 4.7 4 0 0 4 4 4 2 PQQ enzyme repeat Aminotran_1_2 PF00155.21 KIR62753.1 - 7.1e-51 173.5 0.0 8.3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIR62753.1 - 0.00059 18.9 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIR62753.1 - 0.0016 17.8 0.1 0.0023 17.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIR62753.1 - 0.0051 15.4 0.0 0.0079 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 KIR62753.1 - 0.21 10.4 0.0 0.39 9.6 0.0 1.3 1 1 0 1 1 1 0 Allinase RDD PF06271.12 KIR62754.1 - 6.3e-27 94.5 0.2 7.8e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 RDD family DUF2510 PF10708.9 KIR62754.1 - 3.6e-08 33.0 9.6 3.6e-08 33.0 9.6 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2510) RDD PF06271.12 KIR62755.1 - 2.5e-17 63.4 2.2 3.2e-17 63.1 2.2 1.1 1 0 0 1 1 1 1 RDD family Glyoxalase PF00903.25 KIR62756.1 - 6.4e-23 81.4 1.7 8.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIR62756.1 - 2.9e-14 53.2 0.2 1.1e-05 25.7 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KIR62756.1 - 8.3e-08 32.5 1.2 0.0083 16.3 0.2 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KIR62756.1 - 6.8e-06 26.8 0.8 0.013 16.3 0.3 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 KIR62756.1 - 2.3e-05 24.6 0.0 6.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal AsnC_trans_reg PF01037.21 KIR62757.1 - 1.3e-16 60.3 0.1 2.6e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 KIR62757.1 - 1.7e-09 37.3 0.9 7.3e-09 35.3 0.6 2.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR62757.1 - 2.2e-08 33.5 0.1 1.1e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR62757.1 - 0.001 18.8 0.1 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR62757.1 - 0.0011 18.9 0.1 0.0063 16.4 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_41 PF14502.6 KIR62757.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 KIR62757.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Mga PF08280.11 KIR62757.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF977 PF06163.11 KIR62757.1 - 0.069 13.1 0.4 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Fumerase_C PF05683.12 KIR62758.1 - 2.9e-88 294.6 0.0 4.7e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 KIR62758.1 - 5.8e-84 281.7 0.0 7.3e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Histone_H2A_C PF16211.5 KIR62758.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A GntR PF00392.21 KIR62760.1 - 5.5e-17 61.2 0.0 6.6e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Lyase_1 PF00206.20 KIR62762.1 - 1.3e-98 330.2 0.0 1.7e-98 329.8 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KIR62762.1 - 1e-19 70.7 0.3 1e-19 70.7 0.3 2.3 3 0 0 3 3 3 1 Fumarase C C-terminus NIR_SIR_ferr PF03460.17 KIR62762.1 - 0.17 11.8 0.9 2.3 8.1 0.0 2.8 2 1 1 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF397 PF04149.12 KIR62764.1 - 2.6e-22 78.6 1.2 2.8e-22 78.5 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) zf-CGNR PF11706.8 KIR62765.1 - 1.3e-16 60.2 7.4 2e-16 59.6 7.4 1.3 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 KIR62765.1 - 3.5e-14 53.6 15.5 5.5e-14 52.9 15.5 1.3 1 0 0 1 1 1 1 Putative stress-induced transcription regulator EamA PF00892.20 KIR62766.1 - 2.7e-24 85.9 37.9 4e-12 46.5 12.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KIR62766.1 - 0.0012 18.2 2.0 0.14 11.4 0.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KIR62766.1 - 0.068 12.1 1.7 0.11 11.4 1.7 1.2 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Phage_holin_4_1 PF05105.12 KIR62766.1 - 0.09 12.9 1.1 0.2 11.8 1.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family HAD_2 PF13419.6 KIR62767.1 - 2.1e-14 54.0 0.0 3.8e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR62767.1 - 5.6e-10 39.9 0.0 8.6e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR62767.1 - 1.5e-09 37.8 0.0 3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIR62767.1 - 0.28 11.6 3.1 2.3 8.6 1.7 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_1e PF01406.19 KIR62768.1 - 7.7e-106 353.8 0.0 9.4e-106 353.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KIR62768.1 - 1.7e-09 38.0 0.4 3.5e-09 37.0 0.4 1.5 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 KIR62768.1 - 2.2e-08 33.2 0.0 0.0002 20.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KIR62768.1 - 0.00016 20.8 0.0 0.019 13.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KIR62768.1 - 0.1 10.8 0.0 1.1 7.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) SpoU_methylase PF00588.19 KIR62769.1 - 5.2e-36 123.9 0.0 7.7e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KIR62769.1 - 1.1e-16 60.8 0.0 2.5e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding ABC_tran PF00005.27 KIR62770.1 - 2.3e-30 105.9 0.0 4.5e-30 104.9 0.0 1.5 2 0 0 2 2 1 1 ABC transporter OB_MalK PF17912.1 KIR62770.1 - 5.3e-09 36.8 0.1 1.9e-08 35.0 0.1 2.0 1 0 0 1 1 1 1 MalK OB fold domain TOBE_2 PF08402.10 KIR62770.1 - 9.3e-07 28.9 0.7 2.8e-06 27.4 0.2 2.1 2 0 0 2 2 2 1 TOBE domain TOBE PF03459.17 KIR62770.1 - 1.7e-05 25.0 0.1 9.9e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 TOBE domain AAA_22 PF13401.6 KIR62770.1 - 7.6e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KIR62770.1 - 0.00062 19.7 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_21 PF13304.6 KIR62770.1 - 0.00066 19.6 0.0 0.1 12.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR62770.1 - 0.00086 19.7 0.1 0.0017 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR62770.1 - 0.0042 17.0 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 KIR62770.1 - 0.0075 15.7 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KIR62770.1 - 0.015 14.5 0.0 0.64 9.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KIR62770.1 - 0.039 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KIR62770.1 - 0.083 12.5 0.1 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIR62770.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIR62770.1 - 0.11 12.7 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIR62770.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIR62770.1 - 0.29 10.8 0.0 0.36 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain HTH_18 PF12833.7 KIR62771.1 - 1.1e-26 92.9 1.7 1.6e-26 92.4 1.7 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR62771.1 - 7e-19 67.4 0.0 1.3e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Glyoxalase PF00903.25 KIR62772.1 - 1.4e-10 41.5 0.0 2.2e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M4 PF01447.18 KIR62773.1 - 5.8e-49 166.3 4.5 5.8e-49 166.3 4.5 3.2 4 0 0 4 4 4 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 KIR62773.1 - 7.4e-46 156.1 0.8 1.6e-45 155.0 0.8 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain FTP PF07504.13 KIR62773.1 - 2.2e-13 49.8 1.4 8.6e-13 47.9 1.4 2.1 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 KIR62773.1 - 0.00062 20.3 0.2 0.0032 18.0 0.0 2.4 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain Big_3 PF07523.12 KIR62773.1 - 0.009 16.3 2.0 0.071 13.4 0.7 2.7 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) HNH_5 PF14279.6 KIR62774.1 - 6.9e-15 54.6 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 KIR62774.1 - 1.7e-11 44.1 0.0 3.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KIR62774.1 - 1.3e-08 34.6 0.0 3.2e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease zf-ribbon_3 PF13248.6 KIR62774.1 - 0.01 15.2 0.7 0.01 15.2 0.7 1.8 2 0 0 2 2 2 0 zinc-ribbon domain RseC_MucC PF04246.12 KIR62775.1 - 0.41 10.6 2.1 0.71 9.8 2.1 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Fe-ADH PF00465.19 KIR62776.1 - 3.4e-115 384.7 1.9 3.4e-115 384.7 1.9 2.3 3 1 1 4 4 4 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 KIR62776.1 - 7.3e-26 90.7 4.7 1.5e-21 76.5 6.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 KIR62776.1 - 1.4e-16 61.0 0.3 2.1e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Amino_oxidase PF01593.24 KIR62777.1 - 5.5e-29 101.8 0.3 6.9e-29 101.4 0.3 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR62777.1 - 4e-13 49.4 0.4 1.2e-12 47.8 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR62777.1 - 3.1e-11 43.5 5.4 1e-10 41.8 5.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR62777.1 - 8.5e-08 31.8 0.0 2.5e-05 23.7 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR62777.1 - 2.4e-07 30.2 4.4 1.4e-06 27.7 3.6 2.4 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KIR62777.1 - 1.1e-06 28.3 1.0 1.6e-06 27.8 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR62777.1 - 2.4e-06 28.0 0.1 3.4e-05 24.3 0.9 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR62777.1 - 2.8e-06 26.3 0.3 0.00021 20.1 3.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KIR62777.1 - 1.2e-05 25.4 0.8 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KIR62777.1 - 4.5e-05 22.9 3.1 8e-05 22.0 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIR62777.1 - 0.0002 20.7 0.8 0.00032 20.0 0.8 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KIR62777.1 - 0.0018 17.6 1.4 0.0029 16.9 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KIR62777.1 - 0.0025 17.0 2.9 0.0048 16.0 2.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIR62777.1 - 0.0041 16.2 0.3 0.0089 15.1 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIR62777.1 - 0.01 15.1 0.4 0.019 14.3 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIR62777.1 - 0.013 14.3 0.0 0.093 11.5 0.1 1.9 2 0 0 2 2 2 0 MCRA family Trp_halogenase PF04820.14 KIR62777.1 - 0.26 10.1 2.7 0.4 9.5 2.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 KIR62777.1 - 0.29 11.0 1.2 0.46 10.3 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 KIR62779.1 - 1.2e-36 126.5 27.0 1.5e-36 126.1 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIR62779.1 - 1.5e-36 126.0 28.6 1.7e-36 125.8 28.4 1.2 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KIR62779.1 - 2 7.0 14.0 0.53 8.9 6.8 2.8 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein PAP2 PF01569.21 KIR62780.1 - 6.7e-10 38.9 3.4 1e-09 38.3 2.8 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KIR62780.1 - 0.042 13.5 14.3 0.55 9.9 14.0 2.7 1 1 0 1 1 1 0 PAP2 superfamily Amidohydro_1 PF01979.20 KIR62781.1 - 2.6e-29 102.6 4.8 3.3e-29 102.3 4.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIR62781.1 - 3.4e-09 36.7 12.7 1.2e-07 31.6 0.3 3.2 2 1 1 3 3 3 2 Amidohydrolase family ROK PF00480.20 KIR62782.1 - 4.9e-56 190.4 4.4 5.6e-56 190.2 4.4 1.0 1 0 0 1 1 1 1 ROK family Hydant_A_N PF05378.13 KIR62782.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region SIS PF01380.22 KIR62783.1 - 6.5e-09 35.7 0.0 0.0013 18.6 0.0 2.4 2 1 0 2 2 2 2 SIS domain DeoRC PF00455.22 KIR62784.1 - 1.9e-46 158.0 0.2 2.6e-46 157.5 0.2 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 KIR62784.1 - 1.3e-17 63.3 0.1 3.5e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KIR62784.1 - 2.5e-05 24.1 0.1 4.7e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 KIR62784.1 - 4.5e-05 23.4 0.4 0.00035 20.6 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Rib_5-P_isom_A PF06026.14 KIR62784.1 - 0.00023 20.8 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) HTH_AsnC-type PF13404.6 KIR62784.1 - 0.00074 19.3 0.3 0.0025 17.6 0.1 2.0 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR62784.1 - 0.0023 17.5 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR62784.1 - 0.0037 17.1 0.4 0.016 15.1 0.2 2.1 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KIR62784.1 - 0.0038 17.0 1.1 0.028 14.2 0.1 2.5 3 0 0 3 3 2 1 Homeodomain-like domain MarR PF01047.22 KIR62784.1 - 0.0043 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 MarR family Put_DNA-bind_N PF06971.13 KIR62784.1 - 0.0061 16.5 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative DNA-binding protein N-terminus Rrf2 PF02082.20 KIR62784.1 - 0.0091 16.3 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator GntR PF00392.21 KIR62784.1 - 0.01 15.4 0.2 0.027 14.1 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Mga PF08280.11 KIR62784.1 - 0.033 14.2 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_31 PF13560.6 KIR62784.1 - 0.056 13.8 0.9 0.45 10.9 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR62784.1 - 0.066 13.2 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 KIR62784.1 - 0.083 13.0 0.7 0.91 9.7 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2922 PF11148.8 KIR62784.1 - 0.14 11.9 0.0 17 5.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) ABC_tran PF00005.27 KIR62785.1 - 3.6e-28 98.8 0.0 5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR62785.1 - 1.9e-12 47.6 0.3 1.7e-06 28.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIR62785.1 - 0.00087 19.1 0.1 0.00087 19.1 0.1 2.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIR62785.1 - 0.0033 17.7 0.1 0.018 15.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 KIR62785.1 - 0.019 13.9 0.1 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 KIR62785.1 - 0.027 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR62785.1 - 0.028 14.8 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KIR62785.1 - 0.039 13.5 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KIR62785.1 - 0.12 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIR62785.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 KIR62785.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 KIR62786.1 - 4e-12 46.0 3.2 5.1e-12 45.7 3.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR62786.1 - 0.0018 18.3 10.1 0.0027 17.7 6.9 2.5 3 1 0 3 3 3 1 ABC-2 family transporter protein DUF4834 PF16118.5 KIR62786.1 - 0.98 10.4 0.1 0.98 10.4 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF1700 PF08006.11 KIR62786.1 - 2.2 7.8 6.7 0.45 10.0 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Herpes_UL73 PF03554.13 KIR62786.1 - 8.1 6.5 6.4 3.4 7.7 0.1 2.9 3 0 0 3 3 3 0 UL73 viral envelope glycoprotein DUF3263 PF11662.8 KIR62787.1 - 6.9e-36 121.9 1.6 9.7e-36 121.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3263) Acetyltransf_3 PF13302.7 KIR62790.1 - 7.5e-14 52.6 0.0 8.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR62790.1 - 1.1e-12 48.2 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR62790.1 - 6.3e-05 22.7 0.1 9.5e-05 22.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_42 PF06224.12 KIR62790.1 - 9.1e-05 22.1 1.2 0.00012 21.8 1.2 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain Acetyltransf_10 PF13673.7 KIR62790.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR62790.1 - 0.021 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR62790.1 - 0.067 13.3 0.8 0.1 12.8 0.8 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIR62790.1 - 0.076 13.2 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA PF00004.29 KIR62791.1 - 6.8e-56 188.3 0.0 9.6e-41 139.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIR62791.1 - 2.2e-19 68.9 18.5 1.5e-10 40.7 0.5 3.5 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KIR62791.1 - 7.8e-14 52.4 5.3 5.8e-06 26.8 0.4 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KIR62791.1 - 2.8e-08 33.8 0.2 0.0016 18.4 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_N PF02359.18 KIR62791.1 - 1.8e-07 31.2 0.0 7.6e-07 29.2 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 KIR62791.1 - 1.9e-07 31.2 0.2 0.37 10.7 0.0 4.3 3 1 1 4 4 4 2 NACHT domain AAA_18 PF13238.6 KIR62791.1 - 2.5e-06 28.1 0.0 0.023 15.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIR62791.1 - 3e-06 27.1 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 KIR62791.1 - 4.6e-06 26.3 9.9 0.002 17.7 0.6 3.1 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIR62791.1 - 6.9e-06 26.4 0.0 0.12 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIR62791.1 - 8e-06 26.1 0.1 0.24 11.5 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KIR62791.1 - 1.2e-05 25.6 0.3 0.75 10.1 0.3 3.5 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KIR62791.1 - 1.8e-05 24.5 0.1 0.11 12.2 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KIR62791.1 - 4.1e-05 23.4 0.0 0.027 14.2 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIR62791.1 - 0.00013 21.8 2.5 0.062 13.0 1.4 3.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR62791.1 - 0.00018 21.2 0.1 0.068 12.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIR62791.1 - 0.00021 21.7 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KIR62791.1 - 0.00029 20.1 0.1 0.58 9.3 0.1 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_19 PF13245.6 KIR62791.1 - 0.00032 21.0 0.3 0.74 10.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KIR62791.1 - 0.00042 20.9 0.2 0.4 11.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 KIR62791.1 - 0.00045 20.3 0.0 0.0052 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KIR62791.1 - 0.00069 18.9 0.6 0.78 9.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 KIR62791.1 - 0.00069 18.8 0.2 0.51 9.4 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TsaE PF02367.17 KIR62791.1 - 0.00073 19.5 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KIR62791.1 - 0.00078 19.4 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIR62791.1 - 0.0024 17.8 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KIR62791.1 - 0.0047 16.5 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 KIR62791.1 - 0.0053 16.9 0.0 0.74 9.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIR62791.1 - 0.0056 16.1 1.0 0.63 9.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KIR62791.1 - 0.0082 15.9 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KIR62791.1 - 0.012 15.1 2.7 4.2 6.8 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein NTPase_1 PF03266.15 KIR62791.1 - 0.013 15.4 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 KIR62791.1 - 0.014 15.1 0.0 2.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Glyco_transf_21 PF13506.6 KIR62791.1 - 0.017 14.6 1.4 13 5.2 0.1 3.5 3 0 0 3 3 3 0 Glycosyl transferase family 21 AAA_2 PF07724.14 KIR62791.1 - 0.024 14.7 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) ATP_bind_1 PF03029.17 KIR62791.1 - 0.028 14.2 0.3 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 KIR62791.1 - 0.033 13.0 0.9 5.9 5.6 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 KIR62791.1 - 0.05 13.7 0.4 9.5 6.3 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Vps4_C PF09336.10 KIR62791.1 - 0.051 13.6 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AFG1_ATPase PF03969.16 KIR62791.1 - 0.068 12.0 0.3 0.3 9.9 0.0 2.1 2 1 0 2 2 2 0 AFG1-like ATPase cobW PF02492.19 KIR62791.1 - 0.073 12.6 0.1 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KIR62791.1 - 0.078 12.9 0.2 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Cytidylate_kin PF02224.18 KIR62791.1 - 0.092 12.5 1.5 0.15 11.8 0.2 2.1 2 0 0 2 2 1 0 Cytidylate kinase SMC_N PF02463.19 KIR62791.1 - 0.18 11.2 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_11 PF13086.6 KIR62791.1 - 0.2 11.4 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIR62791.1 - 0.24 10.6 0.4 14 4.8 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Robl_LC7 PF03259.17 KIR62793.1 - 1.6e-13 50.3 0.8 2e-13 49.9 0.8 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain NIT PF08376.10 KIR62794.1 - 9.5e-14 52.4 6.5 9.5e-14 52.4 6.5 2.0 2 1 0 2 2 2 1 Nitrate and nitrite sensing HAMP PF00672.25 KIR62794.1 - 6.8e-10 39.2 3.8 3e-09 37.1 2.5 2.8 3 0 0 3 3 3 1 HAMP domain HATPase_c PF02518.26 KIR62794.1 - 1e-06 29.2 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR62794.1 - 0.0044 17.0 1.4 0.0074 16.2 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR62794.1 - 0.0063 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SCAB-ABD PF16711.5 KIR62794.1 - 0.086 12.8 0.0 6.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein ABC_tran PF00005.27 KIR62796.1 - 1.1e-27 97.2 0.0 1.8e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Peptidase_S15 PF02129.18 KIR62796.1 - 5.7e-19 68.8 0.1 1.4e-17 64.2 0.2 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KIR62796.1 - 1.2e-16 61.4 0.1 2.2e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KIR62796.1 - 4.7e-15 55.5 0.1 1.2e-12 47.6 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR62796.1 - 1.2e-14 54.6 0.0 1.3e-11 44.7 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KIR62796.1 - 2.1e-10 40.5 0.0 2.6e-06 27.2 0.0 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIR62796.1 - 1.3e-09 37.9 0.0 0.00058 19.4 0.1 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family AAA_21 PF13304.6 KIR62796.1 - 6.5e-09 36.0 0.1 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AXE1 PF05448.12 KIR62796.1 - 9e-06 24.6 0.3 0.0012 17.6 0.3 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 KIR62796.1 - 0.00055 19.7 0.0 0.0082 15.8 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KIR62796.1 - 0.0011 18.8 0.1 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KIR62796.1 - 0.0058 16.6 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AAA_23 PF13476.6 KIR62796.1 - 0.046 14.2 0.0 0.072 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain FSH1 PF03959.13 KIR62796.1 - 0.062 13.0 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 KIR62796.1 - 0.068 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein AAA_30 PF13604.6 KIR62796.1 - 0.11 12.2 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain MHYT PF03707.16 KIR62796.1 - 1.8 8.8 6.1 1.1 9.5 1.5 2.7 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat ABC2_membrane_2 PF12679.7 KIR62797.1 - 3.5e-16 59.3 14.2 5.1e-16 58.8 14.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR62797.1 - 3.6e-09 36.8 5.6 4.2e-09 36.6 3.5 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 KIR62797.1 - 0.15 11.6 4.1 0.18 11.3 0.0 2.8 3 1 0 3 3 3 0 ABC-2 family transporter protein Phage_holin_3_3 PF16083.5 KIR62797.1 - 0.19 11.9 11.1 0.03 14.4 4.9 2.4 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III ABC2_membrane_3 PF12698.7 KIR62797.1 - 0.7 8.9 15.5 0.15 11.1 11.8 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein DoxX PF07681.12 KIR62798.1 - 2.3e-11 44.1 11.6 2.3e-11 44.1 11.6 1.5 2 0 0 2 2 2 1 DoxX DUF4878 PF12870.7 KIR62799.1 - 0.00094 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) Phage_holin_7_1 PF16081.5 KIR62799.1 - 0.0083 16.3 0.4 0.012 15.7 0.3 1.4 1 1 0 1 1 1 1 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF3418 PF11898.8 KIR62799.1 - 0.075 11.7 0.0 0.084 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Arm-DNA-bind_3 PF13356.6 KIR62799.1 - 0.3 11.5 1.6 0.32 11.4 0.1 1.8 2 1 0 2 2 2 0 Arm DNA-binding domain PALP PF00291.25 KIR62800.1 - 1.7e-60 205.0 2.9 2e-60 204.7 2.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NinF PF05810.12 KIR62800.1 - 0.11 12.4 0.5 0.25 11.3 0.5 1.5 1 0 0 1 1 1 0 NinF protein Acetyltransf_1 PF00583.25 KIR62801.1 - 2.2e-12 47.3 0.0 6.5e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR62801.1 - 1e-06 29.1 0.0 6.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR62801.1 - 6.2e-05 22.9 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR62801.1 - 0.0042 17.2 0.1 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KIR62801.1 - 0.011 15.4 0.1 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PBP_like PF12727.7 KIR62801.1 - 0.018 14.2 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 PBP superfamily domain FR47 PF08445.10 KIR62801.1 - 0.028 14.4 0.4 0.74 9.8 0.1 2.6 3 0 0 3 3 3 0 FR47-like protein Acetyltransf_9 PF13527.7 KIR62801.1 - 0.098 12.7 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.22 KIR62802.1 - 7e-39 133.6 1.5 9.8e-39 133.1 1.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 KIR62802.1 - 0.0097 15.9 2.7 1.7 8.7 0.1 3.4 4 0 0 4 4 4 2 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.25 KIR62803.1 - 4.3e-13 49.5 0.0 5.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIR62803.1 - 8e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIR62803.1 - 0.00013 22.3 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR62803.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR62803.1 - 0.0046 16.6 0.1 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR62803.1 - 0.081 13.6 0.0 0.091 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CSD PF00313.22 KIR62804.1 - 8.6e-30 102.4 1.0 9.4e-30 102.3 1.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KIR62804.1 - 0.003 17.2 1.6 0.0053 16.4 1.6 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 KIR62804.1 - 0.025 14.9 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain Cpn60_TCP1 PF00118.24 KIR62805.1 - 4.8e-96 322.3 13.5 6.5e-96 321.9 13.5 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Kinesin_assoc PF16183.5 KIR62805.1 - 0.088 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Kinesin-associated DAO PF01266.24 KIR62806.1 - 3.5e-51 174.8 8.3 5.4e-51 174.2 7.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KIR62806.1 - 5.1e-33 113.6 0.2 5.1e-33 113.6 0.2 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KIR62806.1 - 2.8e-12 46.4 9.3 7.1e-06 25.4 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIR62806.1 - 5.8e-08 32.5 1.4 3e-07 30.2 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR62806.1 - 4.3e-06 26.2 1.0 3.5e-05 23.2 1.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIR62806.1 - 8.1e-06 25.3 2.9 0.00011 21.6 2.9 2.3 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIR62806.1 - 0.00031 19.9 1.4 0.00055 19.1 1.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIR62806.1 - 0.0016 18.6 2.1 0.004 17.3 0.8 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIR62806.1 - 0.0027 18.2 1.1 0.025 15.1 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIR62806.1 - 0.011 15.7 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIR62806.1 - 0.017 13.8 1.8 0.027 13.2 1.8 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KIR62806.1 - 0.019 14.3 0.7 0.044 13.1 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIR62806.1 - 0.05 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIR62806.1 - 0.15 11.3 0.0 0.41 9.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD-oxidase_C PF02913.19 KIR62808.1 - 1.1e-60 205.4 0.4 1.5e-60 204.9 0.4 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIR62808.1 - 4.8e-39 133.3 4.3 1.1e-38 132.2 4.3 1.6 1 0 0 1 1 1 1 FAD binding domain DUF4031 PF13223.6 KIR62809.1 - 3.8e-30 103.9 0.1 4.4e-30 103.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4031) FUSC_2 PF13515.6 KIR62810.1 - 4.6e-15 55.9 13.9 7.2e-15 55.2 13.9 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 KIR62810.1 - 1.5e-05 25.2 10.7 2.3e-05 24.6 10.7 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 BaxI_1 PF12811.7 KIR62810.1 - 0.12 11.9 6.8 0.12 12.0 5.3 1.5 1 1 1 2 2 2 0 Bax inhibitor 1 like CCSMST1 PF15013.6 KIR62811.1 - 0.2 11.9 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 CCSMST1 family Cpn10 PF00166.21 KIR62812.1 - 1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit OB_RNB PF08206.11 KIR62812.1 - 0.07 12.8 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain AI-2E_transport PF01594.16 KIR62813.1 - 5.1e-65 219.8 28.8 5.9e-65 219.6 28.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter Phage_holin_6_1 PF09682.10 KIR62813.1 - 0.028 14.8 4.4 0.045 14.2 0.4 2.9 2 1 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) ApoO PF09769.9 KIR62813.1 - 0.53 10.2 2.1 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein O Helicase_C_2 PF13307.6 KIR62814.1 - 1.3e-27 97.0 0.0 1.9e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 KIR62814.1 - 9.2e-08 32.0 0.3 0.0056 16.5 0.1 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KIR62814.1 - 0.00073 19.6 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 KIR62814.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 RTP1_C2 PF10304.9 KIR62814.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 DUF402 PF04167.13 KIR62815.1 - 7.2e-14 51.7 0.3 1.5e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF402) Sigma70_r2 PF04542.14 KIR62816.1 - 2.8e-10 39.8 0.3 7.4e-10 38.5 0.3 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR62816.1 - 3.1e-10 39.6 0.1 5.6e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 SnoaL_2 PF12680.7 KIR62816.1 - 5.4e-07 30.2 0.9 1.3e-06 29.0 0.9 1.7 1 0 0 1 1 1 1 SnoaL-like domain Sigma70_r4 PF04545.16 KIR62816.1 - 9.8e-05 21.8 0.1 0.00018 21.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 DUF4440 PF14534.6 KIR62816.1 - 0.037 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KIR62816.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain PhoU_div PF01865.16 KIR62817.1 - 9.2e-24 84.0 0.1 1.1e-23 83.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 VraX PF17412.2 KIR62817.1 - 0.0097 15.5 0.2 0.069 12.8 0.2 2.4 3 0 0 3 3 3 1 Family of unknown function NPV_P10 PF05531.12 KIR62817.1 - 0.31 11.5 2.2 57 4.3 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PHO4 PF01384.20 KIR62818.1 - 1e-82 277.9 34.1 9.2e-82 274.8 34.1 1.9 1 1 0 1 1 1 1 Phosphate transporter family DUF4396 PF14342.6 KIR62818.1 - 0.00027 21.3 3.4 0.00027 21.3 3.4 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4396) GFO_IDH_MocA PF01408.22 KIR62819.1 - 4.3e-21 76.0 0.1 7.3e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR62819.1 - 0.00066 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KIR62819.1 - 0.013 16.0 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIR62819.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 KIR62819.1 - 0.021 15.5 0.1 0.035 14.8 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NUDIX PF00293.28 KIR62820.1 - 2.4e-08 34.1 0.7 6.7e-06 26.2 0.7 3.0 1 1 0 1 1 1 1 NUDIX domain ABC_tran PF00005.27 KIR62821.1 - 2.9e-31 108.8 0.0 4.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR62821.1 - 1.6e-08 34.7 0.0 0.00079 19.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR62821.1 - 5.9e-08 32.4 0.0 0.0074 15.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIR62821.1 - 8.6e-05 22.4 0.0 0.00017 21.4 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIR62821.1 - 0.00014 22.2 0.0 0.00025 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR62821.1 - 0.00052 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR62821.1 - 0.0011 19.5 0.1 0.0028 18.2 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIR62821.1 - 0.0013 18.5 0.0 0.0029 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR62821.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 KIR62821.1 - 0.0031 17.7 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KIR62821.1 - 0.0057 16.6 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIR62821.1 - 0.023 15.1 0.1 0.043 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 KIR62821.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KIR62821.1 - 0.036 14.6 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KIR62821.1 - 0.047 12.9 0.0 0.094 11.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 KIR62821.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KIR62821.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIR62821.1 - 0.069 13.5 0.0 0.27 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KIR62821.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KIR62821.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIR62821.1 - 0.074 13.5 0.1 0.77 10.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KIR62821.1 - 0.077 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KIR62821.1 - 0.13 11.1 0.1 0.77 8.5 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_13 PF13166.6 KIR62821.1 - 0.16 10.6 0.1 0.25 10.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIR62821.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BPD_transp_1 PF00528.22 KIR62822.1 - 5.3e-27 94.8 13.6 5.3e-27 94.8 13.6 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR62823.1 - 2.7e-16 59.9 15.1 2.7e-16 59.9 15.1 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Flg_bb_rod PF00460.20 KIR62823.1 - 0.044 13.7 1.6 0.17 11.8 1.6 2.0 1 0 0 1 1 1 0 Flagella basal body rod protein CoatB PF10389.9 KIR62823.1 - 4.3 7.3 12.0 2.3 8.1 4.8 3.0 2 0 0 2 2 2 0 Bacteriophage coat protein B PBP_like_2 PF12849.7 KIR62824.1 - 6e-62 209.9 10.9 7.5e-62 209.5 10.9 1.0 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 KIR62824.1 - 1.6e-17 64.4 11.2 2.1e-17 64.1 11.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 KIR62824.1 - 1.1e-11 44.2 0.0 2.7e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 PBP superfamily domain Acetyltransf_1 PF00583.25 KIR62825.1 - 3.8e-24 85.2 0.1 6.3e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR62825.1 - 1.2e-13 51.0 0.0 2.4e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR62825.1 - 5.9e-13 49.0 0.1 4.3e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR62825.1 - 1.4e-10 41.0 0.1 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 KIR62825.1 - 2.2e-09 38.1 0.0 7.9e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR62825.1 - 2.4e-05 24.4 0.6 0.15 12.2 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIR62825.1 - 0.00013 22.0 0.5 0.71 10.0 0.1 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR62825.1 - 0.00021 21.0 0.2 0.00092 18.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Polysacc_deac_1 PF01522.21 KIR62826.1 - 1.2e-29 102.7 0.0 1.8e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4719 PF15843.5 KIR62826.1 - 0.075 13.1 1.1 0.13 12.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Trans_reg_C PF00486.28 KIR62827.1 - 9.7e-29 99.3 0.0 1.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Zincin_2 PF10103.9 KIR62828.1 - 0.062 12.6 0.5 0.083 12.1 0.5 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase Rick_17kDa_Anti PF05433.15 KIR62828.1 - 6.7 6.7 19.5 1.3 8.9 1.0 4.3 4 0 0 4 4 4 0 Glycine zipper 2TM domain DUF2993 PF11209.8 KIR62829.1 - 2.1e-32 113.1 12.6 2.4e-32 112.9 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Rhodanese PF00581.20 KIR62830.1 - 1.5e-36 125.2 0.3 1.2e-17 64.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF1416 PF07210.12 KIR62831.1 - 2.3e-41 139.6 0.5 2.6e-41 139.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1416) CarboxypepD_reg PF13620.6 KIR62831.1 - 1.6e-09 37.9 3.7 2.3e-09 37.4 3.7 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain bMG3 PF11974.8 KIR62831.1 - 0.0012 18.9 0.2 0.0015 18.5 0.2 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain SdrD_B PF17210.3 KIR62831.1 - 0.0053 17.0 0.1 0.0098 16.1 0.1 1.5 1 1 0 1 1 1 1 SdrD B-like domain UDP-g_GGTase PF06427.11 KIR62831.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_6 PF17936.1 KIR62831.1 - 3.4 8.0 7.6 0.083 13.2 0.5 2.2 2 1 1 3 3 3 0 Bacterial Ig domain DivIVA PF05103.13 KIR62833.1 - 2e-07 31.1 0.0 2.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 DivIVA protein DivIC PF04977.15 KIR62833.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator GntR PF00392.21 KIR62834.1 - 1.8e-15 56.3 0.0 2e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 KIR62834.1 - 0.002 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MerR PF00376.23 KIR62834.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 MerR family regulatory protein HTH_Tnp_ISL3 PF13542.6 KIR62834.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 KIR62834.1 - 0.1 13.0 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator HTH_41 PF14502.6 KIR62834.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF664 PF04978.12 KIR62835.1 - 1.3e-46 158.7 0.4 2e-46 158.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR62835.1 - 4.5e-11 43.4 2.3 4.5e-11 43.4 2.3 1.6 2 0 0 2 2 2 1 DinB superfamily Tad PF13400.6 KIR62835.1 - 0.94 9.8 2.7 2.4 8.6 2.7 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like GDE_N_bis PF14742.6 KIR62837.1 - 8.2e-43 146.2 0.1 1.1e-42 145.8 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of (some) glycogen debranching enzymes GDE_C PF06202.14 KIR62837.1 - 3.5e-09 36.1 0.0 3.1e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase SCP2 PF02036.17 KIR62838.1 - 0.0034 17.9 0.0 0.0038 17.7 0.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family DrsE PF02635.15 KIR62839.1 - 2.4e-09 37.6 0.0 2.9e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 KIR62839.1 - 0.011 15.6 0.1 4 7.3 0.0 2.1 2 0 0 2 2 2 0 DsrE/DsrF/DrsH-like family DUF1794 PF08768.11 KIR62840.1 - 6.2e-47 159.3 0.0 7.3e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) FUR PF01475.19 KIR62841.1 - 7.6e-23 80.9 0.0 9.3e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 KIR62841.1 - 0.0045 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 KIR62841.1 - 0.028 14.8 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 Penicillinase repressor PadR PF03551.14 KIR62841.1 - 0.052 13.5 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TF_Zn_Ribbon PF08271.12 KIR62841.1 - 0.052 13.1 0.5 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Ribosomal_L37e PF01907.19 KIR62841.1 - 0.068 13.3 1.6 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e mono-CXXC PF15626.6 KIR62841.1 - 0.1 13.0 0.1 6.9 7.1 0.0 2.2 2 0 0 2 2 2 0 single CXXC unit Rubredoxin_2 PF18073.1 KIR62841.1 - 0.6 9.9 2.7 12 5.8 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain GCV_T PF01571.21 KIR62842.1 - 5.4e-32 111.2 0.0 7.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIR62842.1 - 8e-05 22.5 0.6 0.00025 20.9 0.1 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain BCAS3 PF12490.8 KIR62842.1 - 0.29 10.6 0.0 0.43 10.1 0.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 BKACE PF05853.12 KIR62843.1 - 4.4e-84 282.0 0.2 5.3e-84 281.8 0.2 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme Asparaginase_II PF06089.12 KIR62844.1 - 1.3e-114 382.5 1.7 1.5e-114 382.4 1.7 1.0 1 0 0 1 1 1 1 L-asparaginase II Abhydrolase_1 PF00561.20 KIR62845.1 - 2.8e-20 73.1 0.0 3.6e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR62845.1 - 2.3e-18 67.6 17.5 2.8e-18 67.3 17.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR62845.1 - 2.2e-07 30.4 0.1 5.3e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIR62845.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.5 2 0 0 2 2 2 1 Putative esterase FIST PF08495.10 KIR62845.1 - 0.048 13.7 0.1 0.074 13.1 0.1 1.4 1 1 0 1 1 1 0 FIST N domain Abhydrolase_2 PF02230.16 KIR62845.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ndr PF03096.14 KIR62845.1 - 0.2 10.3 0.0 0.39 9.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family HTH_3 PF01381.22 KIR62846.1 - 1.3e-15 57.1 0.5 2.7e-15 56.1 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR62846.1 - 3.6e-14 52.8 0.5 3.6e-14 52.8 0.5 2.7 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR62846.1 - 6e-10 39.0 0.0 9.3e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KIR62846.1 - 0.005 16.4 0.1 0.038 13.5 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_25 PF13413.6 KIR62846.1 - 0.0055 16.5 0.3 0.016 15.1 0.3 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR62846.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain LTXXQ PF07813.12 KIR62846.1 - 0.023 15.4 2.8 0.023 15.4 2.8 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein HTH_AsnC-type PF13404.6 KIR62846.1 - 0.037 13.9 0.1 0.037 13.9 0.1 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_37 PF13744.6 KIR62846.1 - 0.061 13.3 2.6 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 KIR62846.1 - 0.097 13.0 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 KIR62846.1 - 0.1 12.5 0.4 2.8 8.0 0.0 2.7 2 1 1 3 3 3 0 MarR family DUF2516 PF10724.9 KIR62848.1 - 1.1e-24 86.5 3.4 1.4e-24 86.1 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2516) DUF2048 PF09752.9 KIR62848.1 - 0.075 12.1 0.5 0.083 12.0 0.5 1.0 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF805 PF05656.14 KIR62848.1 - 2.8 8.4 6.3 16 6.0 6.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Abhydrolase_1 PF00561.20 KIR62849.1 - 1.4e-07 31.4 0.0 7.6e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR62849.1 - 5.2e-07 29.2 0.1 1.1e-05 24.9 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR62849.1 - 0.05 13.7 0.1 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 TAP-like protein RlaP PF10127.9 KIR62850.1 - 9.9e-22 77.7 0.0 1.5e-21 77.1 0.0 1.3 1 1 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 KIR62850.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain BCA_ABC_TP_C PF12399.8 KIR62850.1 - 0.15 12.0 0.7 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter adh_short PF00106.25 KIR62851.1 - 2.9e-17 62.8 0.0 1.1e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR62851.1 - 5.1e-15 55.7 0.0 1.5e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR62851.1 - 0.066 13.1 0.7 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 KR domain WYL PF13280.6 KIR62852.1 - 2.8e-42 144.7 0.2 4e-42 144.2 0.2 1.2 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 KIR62852.1 - 2.5e-16 59.3 0.1 4.1e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 KIR62852.1 - 7.8e-05 23.0 0.1 0.00019 21.7 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_29 PF13551.6 KIR62852.1 - 0.00038 20.4 0.2 0.00095 19.1 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_DeoR PF08220.12 KIR62852.1 - 0.00091 18.9 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 KIR62852.1 - 0.001 19.1 1.0 0.003 17.6 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 KIR62852.1 - 0.0028 17.5 0.1 0.0072 16.2 0.1 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 KIR62852.1 - 0.0094 16.1 0.1 0.036 14.2 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 KIR62852.1 - 0.011 15.5 0.8 0.67 9.8 1.0 2.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIR62852.1 - 0.013 15.1 1.4 0.029 14.0 0.2 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 KIR62852.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.9 2 0 0 2 2 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KIR62852.1 - 0.031 14.1 0.7 0.031 14.1 0.7 2.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KIR62852.1 - 0.1 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_17 PF12728.7 KIR62852.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 KIR62852.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_Mga PF08280.11 KIR62852.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TetR_N PF00440.23 KIR62852.1 - 0.16 11.8 1.0 0.24 11.2 0.0 1.8 2 0 0 2 2 1 0 Bacterial regulatory proteins, tetR family EI24 PF07264.11 KIR62853.1 - 5.2e-31 108.3 14.3 6.1e-31 108.0 14.3 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ribonuc_L-PSP PF01042.21 KIR62855.1 - 2.5e-20 72.7 0.5 2.9e-20 72.5 0.5 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peripla_BP_3 PF13377.6 KIR62856.1 - 8.7e-39 133.5 3.3 8.7e-39 133.5 3.3 2.4 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR62856.1 - 3.2e-25 89.1 0.0 4.8e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR62856.1 - 9.1e-17 60.6 1.8 2.3e-16 59.3 1.8 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR62856.1 - 7.6e-13 48.6 0.0 2.4e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 KIR62856.1 - 1.7e-06 28.0 0.3 1.7e-06 28.0 0.3 1.7 2 0 0 2 2 2 1 Periplasmic binding protein HTH_31 PF13560.6 KIR62856.1 - 0.00039 20.7 1.6 0.00039 20.7 1.6 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62856.1 - 0.00053 20.0 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_IclR PF09339.10 KIR62856.1 - 0.0078 16.0 0.3 0.025 14.4 0.3 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain TetR_N PF00440.23 KIR62856.1 - 0.029 14.1 0.1 0.12 12.2 0.1 2.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family MarR_2 PF12802.7 KIR62856.1 - 0.039 13.8 1.1 0.2 11.5 0.3 2.6 3 0 0 3 3 3 0 MarR family Sigma70_r4 PF04545.16 KIR62856.1 - 0.04 13.4 1.2 0.64 9.6 0.1 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_38 PF13936.6 KIR62856.1 - 0.044 13.5 0.2 0.098 12.4 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 KIR62856.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain rRNA_methylase PF06962.12 KIR62856.1 - 0.097 12.6 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative rRNA methylase YdaS_antitoxin PF15943.5 KIR62856.1 - 0.099 12.5 0.1 0.37 10.7 0.1 2.0 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KIR62856.1 - 0.11 12.3 1.2 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_6 PF01418.17 KIR62856.1 - 0.17 11.9 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family MHB PF16525.5 KIR62856.1 - 0.18 12.1 0.1 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding HTH_7 PF02796.15 KIR62856.1 - 0.27 11.4 0.9 0.58 10.3 0.1 2.0 3 0 0 3 3 2 0 Helix-turn-helix domain of resolvase Glyco_hydro_1 PF00232.18 KIR62857.1 - 2e-158 527.6 0.0 2.3e-158 527.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 BPD_transp_1 PF00528.22 KIR62858.1 - 6.1e-21 75.0 11.5 6.1e-21 75.0 11.5 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3159 PF11361.8 KIR62858.1 - 0.33 10.7 11.9 5.2 6.8 11.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) SBP_bac_8 PF13416.6 KIR62859.1 - 1.3e-27 97.4 12.4 1.8e-27 96.9 12.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR62859.1 - 3.2e-15 56.9 13.9 8.1e-15 55.6 13.9 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR62859.1 - 0.00094 18.7 1.1 0.002 17.6 1.1 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein MDMPI_N PF11716.8 KIR62860.1 - 3.4e-22 79.7 7.0 3.4e-22 79.7 7.0 2.2 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 KIR62860.1 - 2.8e-13 50.5 9.3 2.8e-13 50.5 9.3 2.3 3 0 0 3 3 3 1 MDMPI C-terminal domain DinB_2 PF12867.7 KIR62860.1 - 0.0012 19.3 0.5 0.0012 19.3 0.5 1.8 2 0 0 2 2 2 1 DinB superfamily SCP2 PF02036.17 KIR62860.1 - 0.0013 19.1 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIR62860.1 - 0.16 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal MurB_C PF02873.16 KIR62861.1 - 2.1e-33 114.9 0.0 7.4e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 KIR62861.1 - 5.9e-23 81.2 2.7 1.2e-22 80.1 2.7 1.5 1 0 0 1 1 1 1 FAD binding domain Glycos_transf_1 PF00534.20 KIR62862.1 - 4.2e-36 124.1 0.0 7.1e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR62862.1 - 6.1e-34 117.5 1.1 6.1e-34 117.5 1.1 2.4 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIR62862.1 - 1e-27 97.5 7.8 1e-27 97.5 7.8 3.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KIR62862.1 - 1.8e-27 96.4 0.1 3.6e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIR62862.1 - 2.7e-09 37.3 0.0 6.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR62862.1 - 0.018 15.0 0.0 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KIR62862.1 - 0.031 14.0 0.3 0.18 11.5 0.2 2.0 1 1 0 2 2 2 0 Starch synthase catalytic domain YbjN PF10722.9 KIR62863.1 - 2.2e-24 85.9 0.3 2.9e-24 85.5 0.3 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator CesT PF05932.13 KIR62863.1 - 0.00064 19.8 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family HeH PF12949.7 KIR62864.1 - 0.71 9.6 2.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 HeH/LEM domain Rib_recp_KP_reg PF05104.12 KIR62864.1 - 1.1 10.3 17.5 1.8 9.6 17.5 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MFS_1 PF07690.16 KIR62865.1 - 1.2e-38 132.9 45.8 5.7e-25 88.0 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR62865.1 - 2.3e-15 56.4 21.0 1.1e-09 37.7 5.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KIR62865.1 - 5.8e-07 28.7 12.3 5.6e-06 25.5 11.3 2.0 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 KIR62865.1 - 5.1e-05 21.9 37.6 0.00038 19.0 37.6 1.9 1 1 0 1 1 1 1 Transmembrane secretion effector PTR2 PF00854.21 KIR62865.1 - 0.0082 15.0 4.3 0.045 12.6 0.6 2.7 2 1 1 3 3 3 1 POT family Romo1 PF10247.9 KIR62865.1 - 0.58 10.6 4.5 0.58 10.6 1.9 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 OATP PF03137.20 KIR62865.1 - 6 5.0 7.1 1.4 7.1 0.2 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family His_Phos_1 PF00300.22 KIR62866.1 - 5e-32 111.2 1.4 1.8e-25 89.8 1.2 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) HATPase_c PF02518.26 KIR62867.1 - 2.1e-26 92.6 0.1 3.6e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR62867.1 - 8.2e-15 54.6 0.8 1.5e-14 53.7 0.8 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KIR62867.1 - 3.6e-06 26.8 0.1 7.6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR62867.1 - 0.00067 19.6 0.1 0.0017 18.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 KIR62867.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 GHKL domain Response_reg PF00072.24 KIR62868.1 - 7.6e-29 100.2 0.0 1.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR62868.1 - 1.2e-28 99.0 0.2 3.7e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Ppx-GppA PF02541.16 KIR62870.1 - 1.3e-63 215.2 0.0 1.5e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family K-cyclin_vir_C PF09080.10 KIR62870.1 - 0.0043 17.4 0.9 0.29 11.6 0.0 2.4 1 1 1 2 2 2 1 K cyclin, C terminal FtsA PF14450.6 KIR62870.1 - 0.023 15.1 0.1 3.5 8.1 0.0 2.6 2 1 0 2 2 2 0 Cell division protein FtsA DUF4142 PF13628.6 KIR62870.1 - 0.024 14.9 0.3 0.039 14.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) zf-CGNR PF11706.8 KIR62871.1 - 7.8e-12 44.9 13.8 1.3e-11 44.2 13.8 1.3 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 KIR62871.1 - 1.4e-05 25.7 9.6 2.8e-05 24.8 9.5 1.7 1 1 0 1 1 1 1 Putative stress-induced transcription regulator GSP_synth PF03738.14 KIR62872.1 - 1e-137 459.4 0.0 1.1e-137 459.2 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp Pro_dh PF01619.18 KIR62873.1 - 2.9e-29 102.6 0.0 4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Abhydrolase_6 PF12697.7 KIR62874.1 - 9.2e-19 68.9 17.1 1.1e-18 68.6 17.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR62874.1 - 3e-18 66.4 0.5 1.2e-16 61.1 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR62874.1 - 4.8e-17 62.0 0.5 9.5e-17 61.1 0.5 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIR62874.1 - 0.0021 17.6 0.9 2.5 7.5 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KIR62874.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein AP_endonuc_2 PF01261.24 KIR62874.1 - 0.03 13.8 0.0 0.25 10.8 0.0 2.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Peptidase_S15 PF02129.18 KIR62874.1 - 0.031 13.9 1.0 0.11 12.1 1.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 KIR62874.1 - 0.048 12.2 0.1 0.073 11.6 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TetR_C_33 PF13305.6 KIR62875.1 - 1.1e-25 90.3 6.1 1.1e-25 90.3 6.1 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR62875.1 - 6.5e-05 22.6 3.7 7.4e-05 22.5 0.1 2.7 2 1 0 2 2 2 1 Bacterial regulatory proteins, tetR family DUF2568 PF10823.8 KIR62876.1 - 3.1e-21 75.5 19.7 4.1e-21 75.1 19.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) HAD PF12710.7 KIR62879.1 - 2.8e-27 96.4 1.4 4.1e-27 95.8 1.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR62879.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR62879.1 - 0.0063 16.8 3.0 0.0084 16.4 0.7 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Gram_pos_anchor PF00746.21 KIR62879.1 - 0.14 12.1 1.6 0.32 11.0 1.6 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Sigma70_r2 PF04542.14 KIR62881.1 - 6.2e-17 61.1 0.8 5.2e-16 58.2 1.0 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR62881.1 - 2e-12 46.6 0.1 3.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR62881.1 - 7.7e-10 38.1 0.1 1.6e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR62881.1 - 1.6e-07 31.4 0.2 2.6e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 ECF sigma factor HTH_38 PF13936.6 KIR62881.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 KIR62881.1 - 0.25 11.3 0.0 1.9 8.4 0.0 2.0 2 0 0 2 2 2 0 Phage antitermination protein Q DUF836 PF05768.14 KIR62882.1 - 5.5e-16 58.8 0.0 6.1e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KIR62882.1 - 0.019 15.2 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Hydrolase_like PF13242.6 KIR62883.1 - 7.9e-08 32.3 0.7 1.5e-07 31.4 0.7 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 KIR62883.1 - 2.4e-06 27.7 0.0 2.3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR62883.1 - 0.0002 21.7 1.1 0.011 16.0 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR62883.1 - 0.00088 19.7 4.1 0.0016 18.9 2.9 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase MoCF_biosynth PF00994.24 KIR62883.1 - 0.076 12.7 0.0 1.5 8.5 0.2 2.2 2 1 0 2 2 2 0 Probable molybdopterin binding domain Sensor PF13796.6 KIR62884.1 - 2.9e-40 138.0 25.4 2.9e-40 138.0 25.4 1.8 2 0 0 2 2 2 1 Putative sensor HisKA_3 PF07730.13 KIR62884.1 - 1.9e-12 47.5 5.0 1.9e-12 47.5 5.0 2.2 3 0 0 3 3 3 1 Histidine kinase HATPase_c_2 PF13581.6 KIR62884.1 - 0.00029 20.8 0.1 0.00074 19.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR62884.1 - 0.0022 18.5 0.0 0.0063 17.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VirB3 PF05101.13 KIR62884.1 - 3.1 8.1 8.7 11 6.4 1.0 2.6 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein CoA_binding PF02629.19 KIR62885.1 - 1.1e-20 74.1 0.1 2.4e-20 73.0 0.1 1.6 2 0 0 2 2 2 1 CoA binding domain Put_DNA-bind_N PF06971.13 KIR62885.1 - 1.8e-18 66.3 0.0 2.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus GFO_IDH_MocA PF01408.22 KIR62885.1 - 0.0035 18.1 0.1 0.0055 17.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Rrf2 PF02082.20 KIR62885.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator GlutR_N PF05201.15 KIR62886.1 - 2.6e-43 147.3 0.0 4.3e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 KIR62886.1 - 3.5e-29 101.6 0.0 6.3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 KIR62886.1 - 4.5e-25 87.9 0.2 1.1e-24 86.7 0.1 1.7 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 KIR62886.1 - 0.0027 18.2 0.3 0.051 14.2 0.2 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KIR62886.1 - 0.0037 16.2 0.3 0.0061 15.5 0.3 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Glu_dehyd_C PF16912.5 KIR62886.1 - 0.016 14.7 1.9 0.019 14.4 0.8 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KIR62886.1 - 0.042 14.3 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DnaG_DnaB_bind PF08278.11 KIR62886.1 - 0.072 13.7 3.8 9.5 6.8 0.2 2.8 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding ApbA PF02558.16 KIR62886.1 - 0.23 11.1 0.9 0.44 10.2 0.9 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KIR62886.1 - 0.72 9.2 3.1 0.98 8.7 1.5 1.9 2 0 0 2 2 2 0 ThiF family Porphobil_deam PF01379.20 KIR62887.1 - 6.4e-67 225.0 0.1 8.1e-67 224.7 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KIR62887.1 - 9.1e-21 74.0 0.8 1.7e-20 73.2 0.3 1.7 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain HEM4 PF02602.15 KIR62888.1 - 4.2e-66 222.6 1.0 6e-66 222.1 0.4 1.6 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD TP_methylase PF00590.20 KIR62888.1 - 5.7e-30 104.9 7.2 1.2e-29 103.8 7.2 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases B12-binding PF02310.19 KIR62888.1 - 0.011 15.8 0.0 0.046 13.8 0.0 2.1 1 1 0 1 1 1 0 B12 binding domain Creatinase_N PF01321.18 KIR62888.1 - 0.045 14.4 0.1 2 9.1 0.0 2.8 3 0 0 3 3 3 0 Creatinase/Prolidase N-terminal domain ALAD PF00490.21 KIR62889.1 - 2.5e-135 450.7 0.1 2.9e-135 450.5 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase LTD PF00932.19 KIR62890.1 - 2.8e-17 63.1 2.5 2.5e-16 60.0 0.3 2.6 2 0 0 2 2 2 1 Lamin Tail Domain Exo_endo_phos PF03372.23 KIR62890.1 - 0.00014 21.5 4.0 0.0029 17.1 4.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Calx-beta PF03160.14 KIR62890.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Calx-beta domain HYR PF02494.16 KIR62890.1 - 0.07 13.5 0.2 0.4 11.0 0.2 2.2 2 0 0 2 2 2 0 HYR domain FR47 PF08445.10 KIR62891.1 - 2.3e-09 37.1 0.1 3.6e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KIR62891.1 - 7.1e-09 35.9 0.0 5.5e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR62891.1 - 6.5e-08 32.9 0.1 5.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR62891.1 - 1.8e-06 27.9 0.0 2e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR62891.1 - 0.017 15.3 0.3 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIR62891.1 - 0.027 14.6 1.0 0.4 10.8 0.0 3.0 2 2 1 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR62891.1 - 0.097 12.8 0.5 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SLT_2 PF13406.6 KIR62892.1 - 8.7e-08 31.7 1.9 2.9e-07 30.0 0.1 2.4 2 1 1 3 3 3 1 Transglycosylase SLT domain SLT PF01464.20 KIR62892.1 - 0.00021 20.9 0.0 0.00045 19.9 0.0 1.5 1 1 0 1 1 1 1 Transglycosylase SLT domain Zn-ribbon_8 PF09723.10 KIR62893.1 - 1.5e-12 47.4 0.3 2.3e-12 46.8 0.3 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Adeno_E1B_55K_N PF04623.12 KIR62893.1 - 0.53 11.0 7.5 0.64 10.8 7.1 1.3 1 1 0 1 1 1 0 Adenovirus E1B protein N-terminus Phospholip_A2_3 PF09056.11 KIR62894.1 - 7.4e-35 119.9 3.8 9.4e-35 119.6 3.8 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 GHL10 PF02638.15 KIR62895.1 - 1.1e-87 294.0 0.8 1.5e-87 293.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 KIR62895.1 - 0.06 13.5 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Melibiase PF02065.18 KIR62895.1 - 0.13 11.2 0.0 0.33 9.8 0.0 1.6 1 1 0 1 1 1 0 Melibiase Alpha-L-AF_C PF06964.12 KIR62896.1 - 6.7e-37 127.2 0.0 9.3e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KIR62896.1 - 0.11 12.5 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Glycoside hydrolase family 44 GH-E PF14410.6 KIR62896.1 - 0.3 11.5 1.0 1.3 9.5 0.1 2.4 2 1 1 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF4015 PF13200.6 KIR62897.1 - 0.092 11.8 0.7 0.11 11.5 0.7 1.2 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain PspA_IM30 PF04012.12 KIR62897.1 - 0.12 11.9 0.3 0.15 11.6 0.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family zf_C2H2_10 PF18414.1 KIR62898.1 - 0.076 12.6 4.6 1 8.9 0.2 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger TackOD1 PF18551.1 KIR62898.1 - 0.076 12.7 2.4 0.13 12.0 1.4 1.7 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 KIR62898.1 - 0.87 9.6 6.9 0.17 11.9 3.4 1.6 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.19 KIR62898.1 - 2.8 8.0 6.3 4.8 7.2 3.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KIR62898.1 - 3.5 7.7 7.0 7.7 6.6 1.4 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KIR62898.1 - 5.8 7.0 11.4 1.3 9.1 6.8 2.1 1 1 1 2 2 2 0 Double zinc ribbon Methyltransf_11 PF08241.12 KIR62899.1 - 1e-09 38.9 0.7 3.7e-09 37.1 0.7 2.0 1 1 0 1 1 1 1 Methyltransferase domain BON PF04972.17 KIR62899.1 - 1.1e-06 28.8 0.2 2e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 BON domain Methyltransf_8 PF05148.15 KIR62899.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.6 KIR62899.1 - 8.4e-05 23.2 0.2 0.00073 20.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR62899.1 - 0.00071 20.3 0.1 0.0018 19.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR62899.1 - 0.0016 18.3 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR62899.1 - 0.019 14.8 0.1 0.042 13.7 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIR62899.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4177 PF13783.6 KIR62900.1 - 0.00035 20.8 0.2 0.019 15.2 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4177) ABC_tran PF00005.27 KIR62901.1 - 1.9e-40 138.5 0.1 1e-22 81.1 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIR62901.1 - 4e-16 59.7 9.7 0.00059 19.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR62901.1 - 5.5e-10 39.0 0.3 0.059 12.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR62901.1 - 6.6e-09 35.4 0.5 0.00058 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR62901.1 - 7.4e-09 36.0 0.1 8.2e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIR62901.1 - 2.2e-07 31.6 2.3 0.0016 19.0 0.0 3.0 4 0 0 4 4 3 2 AAA domain Dynamin_N PF00350.23 KIR62901.1 - 3.7e-06 27.1 0.0 0.012 15.6 0.0 2.9 3 0 0 3 3 3 2 Dynamin family AAA_33 PF13671.6 KIR62901.1 - 4.2e-06 27.0 5.8 0.0026 17.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KIR62901.1 - 5.9e-06 26.3 0.4 0.081 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KIR62901.1 - 8.7e-06 25.7 0.7 0.045 13.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KIR62901.1 - 2.7e-05 24.7 0.1 0.18 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KIR62901.1 - 3.1e-05 23.7 2.3 0.017 14.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIR62901.1 - 5.3e-05 23.0 8.4 0.0033 17.2 0.7 3.4 2 2 0 2 2 2 2 AAA domain ABC_tran_Xtn PF12848.7 KIR62901.1 - 0.00013 21.9 12.5 0.0011 18.9 12.5 2.1 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIR62901.1 - 0.00029 20.8 0.3 0.28 11.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 KIR62901.1 - 0.00036 20.3 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF3584 PF12128.8 KIR62901.1 - 0.0005 17.8 12.2 0.01 13.4 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) SRP54 PF00448.22 KIR62901.1 - 0.00056 19.6 0.7 0.91 9.1 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 KIR62901.1 - 0.00074 18.9 0.3 0.15 11.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.6 KIR62901.1 - 0.0012 18.6 0.3 0.79 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR62901.1 - 0.0016 18.9 0.1 0.0016 18.9 0.1 3.4 1 1 1 3 3 3 2 AAA ATPase domain MobB PF03205.14 KIR62901.1 - 0.0021 18.0 0.6 0.58 10.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KIR62901.1 - 0.0021 18.0 0.7 1.1 9.3 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 KIR62901.1 - 0.0024 17.6 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.6 KIR62901.1 - 0.0035 17.4 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIR62901.1 - 0.004 16.9 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KIR62901.1 - 0.0046 17.2 11.5 0.0072 16.6 0.2 3.5 3 1 0 3 3 3 1 AAA domain AAA_27 PF13514.6 KIR62901.1 - 0.006 16.2 3.5 1.5 8.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain NTPase_1 PF03266.15 KIR62901.1 - 0.0073 16.2 0.8 0.3 11.0 0.0 2.4 2 0 0 2 2 2 1 NTPase NB-ARC PF00931.22 KIR62901.1 - 0.0084 15.3 0.6 3.8 6.6 0.2 2.4 2 0 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 KIR62901.1 - 0.0099 14.9 7.3 0.23 10.4 0.3 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KIR62901.1 - 0.014 14.7 0.5 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KIR62901.1 - 0.015 14.4 0.5 0.092 11.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MukB PF04310.12 KIR62901.1 - 0.019 14.8 2.4 5.2 6.8 0.1 3.1 3 0 0 3 3 3 0 MukB N-terminal AAA_5 PF07728.14 KIR62901.1 - 0.035 14.1 1.7 2.6 8.0 0.2 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF4110 PF13422.6 KIR62901.1 - 0.063 13.4 10.1 5.3 7.2 6.4 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4110) ATP_bind_1 PF03029.17 KIR62901.1 - 0.1 12.4 0.2 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KIR62901.1 - 0.16 12.0 4.7 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain PRK PF00485.18 KIR62901.1 - 0.18 11.6 0.5 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 KIR62901.1 - 0.2 12.1 1.4 25 5.3 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIR62901.1 - 0.24 10.9 0.1 13 5.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KIR62901.1 - 0.28 10.6 0.2 0.84 9.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_17 PF13207.6 KIR62901.1 - 1 9.8 7.0 11 6.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.6 KIR62901.1 - 1.2 7.7 5.0 10 4.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KIR62901.1 - 2.1 7.6 7.5 6.1 6.1 0.1 2.7 3 0 0 3 3 2 0 Zeta toxin TPR_19 PF14559.6 KIR62902.1 - 3.2e-14 53.2 1.3 4.2e-13 49.6 0.2 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIR62902.1 - 1.2e-11 44.4 5.2 3.5e-05 24.3 0.8 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIR62902.1 - 8.5e-10 39.1 15.6 4.8e-05 23.9 3.8 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIR62902.1 - 1.4e-08 34.8 0.0 3e-08 33.8 0.0 1.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KIR62902.1 - 4.3e-08 32.7 0.4 0.024 14.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIR62902.1 - 5.7e-08 32.9 1.9 0.079 13.6 0.2 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIR62902.1 - 7.7e-07 29.1 0.2 0.03 14.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIR62902.1 - 3.6e-06 27.2 3.3 0.063 13.6 0.6 3.0 2 2 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KIR62902.1 - 4.4e-05 23.9 4.7 0.0044 17.5 0.5 2.1 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_15 PF13429.6 KIR62902.1 - 0.00022 20.6 0.6 0.00027 20.3 0.6 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIR62902.1 - 0.00025 21.0 0.0 0.015 15.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIR62902.1 - 0.00041 20.8 0.0 0.021 15.3 0.0 2.1 1 1 1 2 2 2 2 Alkyl sulfatase dimerisation TPR_20 PF14561.6 KIR62902.1 - 0.00049 20.4 1.1 0.0048 17.2 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIR62902.1 - 0.00067 19.5 3.0 1.5 9.0 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIR62902.1 - 0.00072 19.7 5.8 0.25 11.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIR62902.1 - 0.0021 17.9 5.3 2.2 8.3 1.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIR62902.1 - 0.0028 17.4 0.1 5.6 7.0 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KIR62902.1 - 0.014 15.0 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 KIR62902.1 - 0.015 15.9 11.4 0.017 15.7 0.8 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 KIR62902.1 - 0.023 14.4 0.3 0.12 12.1 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF4248 PF14053.6 KIR62902.1 - 0.026 14.5 0.2 0.84 9.7 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4248) NatB_MDM20 PF09797.9 KIR62902.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.2 1 1 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_11 PF13414.6 KIR62902.1 - 0.032 13.9 0.0 0.28 10.9 0.0 2.5 3 1 1 4 4 4 0 TPR repeat Fis1_TPR_C PF14853.6 KIR62902.1 - 0.047 13.8 0.6 7.8 6.7 0.0 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 KIR62902.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Smr PF01713.21 KIR62903.1 - 3.2e-11 43.4 0.1 3.6e-11 43.3 0.1 1.0 1 0 0 1 1 1 1 Smr domain Peptidase_M28 PF04389.17 KIR62904.1 - 1.2e-38 132.8 0.0 1.8e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIR62904.1 - 9.5e-05 22.2 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KIR62904.1 - 0.02 13.9 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SpoIIE PF07228.12 KIR62905.1 - 2.2e-32 112.6 0.2 3.6e-32 111.8 0.2 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 KIR62905.1 - 1.3e-11 44.7 0.1 2.5e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain CHASE3 PF05227.13 KIR62906.1 - 4.5e-23 81.7 2.8 4.5e-23 81.7 2.8 2.5 2 0 0 2 2 2 1 CHASE3 domain HATPase_c PF02518.26 KIR62906.1 - 1.1e-21 77.4 0.0 2e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR62906.1 - 1.1e-13 50.9 3.9 1.7e-13 50.3 0.1 3.2 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR62906.1 - 4.5e-09 36.5 0.6 2.8e-08 34.0 0.1 2.6 2 0 0 2 2 2 1 HAMP domain Tropomyosin PF00261.20 KIR62906.1 - 0.03 13.7 1.0 0.061 12.7 1.0 1.4 1 0 0 1 1 1 0 Tropomyosin TelA PF05816.11 KIR62906.1 - 0.032 13.3 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Apolipoprotein PF01442.18 KIR62906.1 - 0.045 13.6 6.3 0.12 12.2 6.3 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HATPase_c_5 PF14501.6 KIR62906.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 GHKL domain ADIP PF11559.8 KIR62906.1 - 0.09 12.9 0.6 0.2 11.7 0.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 KIR62906.1 - 0.13 11.8 1.2 0.15 11.6 0.2 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Response_reg PF00072.24 KIR62907.1 - 3.8e-21 75.3 0.1 4.4e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Inositol_P PF00459.25 KIR62908.1 - 8.4e-37 127.2 0.0 1.2e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.25 KIR62910.1 - 7.9e-47 159.8 0.0 1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR62910.1 - 6.8e-33 114.0 0.0 8.2e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CBM_2 PF00553.19 KIR62910.1 - 2e-11 44.1 0.0 4.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Cellulose binding domain APH PF01636.23 KIR62910.1 - 3.9e-06 27.0 3.0 0.0018 18.2 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIR62910.1 - 0.001 18.4 0.0 0.0044 16.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIR62910.1 - 0.031 13.1 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TrkA_N PF02254.18 KIR62911.1 - 2.6e-25 88.9 0.0 4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 KIR62911.1 - 3.7e-10 39.5 0.1 1.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 TrkA-C domain NAD_binding_2 PF03446.15 KIR62911.1 - 4.9e-06 26.8 0.0 7.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIR62911.1 - 3.1e-05 24.5 0.0 6.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIR62911.1 - 5.7e-05 22.7 0.0 7.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 KIR62911.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KIR62911.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIR62911.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIR62911.1 - 0.0017 18.9 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIR62911.1 - 0.0039 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIR62911.1 - 0.0047 16.9 0.0 0.0067 16.4 0.0 1.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 KIR62911.1 - 0.031 13.5 0.1 0.097 11.9 0.0 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KIR62911.1 - 0.048 13.5 1.2 0.15 11.9 0.2 2.2 1 1 1 3 3 3 0 Rossmann-like domain AlaDh_PNT_C PF01262.21 KIR62911.1 - 0.069 12.4 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LpxI_N PF17930.1 KIR62911.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain TrkH PF02386.16 KIR62912.1 - 2.2e-44 151.8 13.8 1e-43 149.6 13.8 1.7 1 1 0 1 1 1 1 Cation transport protein DUF3775 PF12616.8 KIR62912.1 - 0.12 12.4 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) GDPD PF03009.17 KIR62913.1 - 7.9e-47 160.2 0.0 9.1e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Peripla_BP_6 PF13458.6 KIR62914.1 - 3.4e-57 194.7 19.4 4.8e-57 194.2 19.4 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KIR62914.1 - 3.3e-15 55.9 0.2 2.2e-14 53.3 0.2 1.9 1 1 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 KIR62914.1 - 2.2e-06 27.0 0.1 5.2e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Receptor family ligand binding region ABC_tran PF00005.27 KIR62915.1 - 3.7e-30 105.2 0.0 4.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 KIR62915.1 - 6.9e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 KIR62915.1 - 1.3e-05 25.2 0.2 0.00071 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR62915.1 - 0.0044 17.5 0.1 0.0063 17.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIR62915.1 - 0.041 13.3 0.2 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR62915.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 KIR62915.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 KIR62915.1 - 0.1 12.3 0.2 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIR62916.1 - 4.2e-25 88.9 0.0 5.5e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR62916.1 - 1.5e-11 44.7 0.3 2e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR62916.1 - 0.00038 21.0 0.0 0.00048 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR62916.1 - 0.0016 18.1 0.1 0.0028 17.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR62916.1 - 0.0061 16.8 0.1 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIR62916.1 - 0.014 14.8 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 KIR62916.1 - 0.037 11.5 0.9 0.048 11.2 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_27 PF13514.6 KIR62916.1 - 0.043 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR62916.1 - 0.13 11.9 3.5 0.45 10.2 3.3 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIR62916.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIR62916.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.4 2 0 0 2 2 2 0 AAA ATPase domain BPD_transp_2 PF02653.16 KIR62917.1 - 6.1e-36 124.0 48.5 7.1e-36 123.7 48.5 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 KIR62918.1 - 2.4e-26 92.5 31.3 3.3e-26 92.1 31.3 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DEAD PF00270.29 KIR62919.1 - 4.2e-14 52.7 0.0 6.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR62919.1 - 2.6e-12 47.0 0.0 6.5e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR62919.1 - 7.7e-06 26.0 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pribosyltran PF00156.27 KIR62919.1 - 0.00027 20.5 0.2 0.00052 19.6 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RecQ_Zn_bind PF16124.5 KIR62919.1 - 0.001 19.7 1.2 0.002 18.8 1.2 1.5 1 0 0 1 1 1 1 RecQ zinc-binding AAA_30 PF13604.6 KIR62919.1 - 0.0024 17.6 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain HTH_20 PF12840.7 KIR62919.1 - 0.097 12.7 3.1 0.23 11.5 0.7 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_31 PF13560.6 KIR62921.1 - 2.7e-07 30.8 1.0 1.3e-06 28.6 0.9 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62921.1 - 2.1e-06 27.7 0.0 3.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_IclR PF09339.10 KIR62921.1 - 8.6e-06 25.5 0.0 0.00023 20.9 0.0 2.8 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KIR62921.1 - 1.9e-05 24.3 0.1 4.9e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_19 PF12844.7 KIR62921.1 - 3.2e-05 23.9 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR62921.1 - 0.00016 21.4 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR62921.1 - 0.00033 20.6 0.1 0.00093 19.2 0.1 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_26 PF13443.6 KIR62921.1 - 0.00052 20.4 0.0 0.00079 19.8 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_7 PF02796.15 KIR62921.1 - 0.01 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KIR62921.1 - 0.015 15.4 0.6 0.051 13.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_37 PF13744.6 KIR62921.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 KIR62921.1 - 0.083 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KIR62921.1 - 0.092 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_5 PF01022.20 KIR62921.1 - 0.13 12.1 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_38 PF13936.6 KIR62921.1 - 0.14 11.9 0.3 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_32 PF13679.6 KIR62923.1 - 2.4e-30 105.6 0.0 4.4e-30 104.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR62923.1 - 3.2e-07 30.2 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR62923.1 - 1.3e-05 25.8 0.1 2.9e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR62923.1 - 0.0012 19.4 0.1 0.0025 18.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 KIR62923.1 - 0.0029 17.2 0.7 2.7 7.4 0.4 2.9 1 1 1 2 2 2 2 Methyltransferase TRM13 MTS PF05175.14 KIR62923.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PALP PF00291.25 KIR62923.1 - 0.018 14.4 1.2 0.029 13.8 0.3 1.7 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Methyltransf_12 PF08242.12 KIR62923.1 - 0.073 13.8 0.0 0.24 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIR62923.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 KIR62924.1 - 3.3e-47 160.5 0.0 1.1e-46 158.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR62924.1 - 3e-30 104.8 0.0 1.3e-29 102.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR62924.1 - 0.0036 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIR62924.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Methyltransf_17 PF12692.7 KIR62924.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase AAA_22 PF13401.6 KIR62924.1 - 0.48 10.7 1.8 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3107 PF11305.8 KIR62925.1 - 1.3e-29 102.2 0.1 1.5e-29 102.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) DUF903 PF06004.12 KIR62925.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) TraI_2B PF18340.1 KIR62925.1 - 0.09 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain TetR_N PF00440.23 KIR62926.1 - 4.6e-18 64.7 0.8 1e-17 63.6 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 KIR62926.1 - 0.0073 17.0 1.7 0.0073 17.0 1.7 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 KIR62926.1 - 0.024 14.8 0.0 0.049 13.8 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase TetR_C_24 PF17932.1 KIR62926.1 - 0.05 13.9 0.2 0.083 13.2 0.2 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 KIR62926.1 - 0.054 13.3 2.9 0.13 12.1 0.0 3.1 3 1 1 4 4 4 0 Bacterial regulatory proteins, lacI family TetR_C_4 PF08359.11 KIR62926.1 - 0.071 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region DUF3152 PF11350.8 KIR62928.1 - 1.2e-29 103.5 0.0 3.3e-29 102.1 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3152) Reprolysin_5 PF13688.6 KIR62928.1 - 0.0081 16.3 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIR62928.1 - 0.031 14.8 0.1 0.042 14.4 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.8 KIR62929.1 - 2.2e-31 109.2 0.0 4.8e-29 101.5 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3152) Zn_peptidase PF04228.13 KIR62929.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Reprolysin_5 PF13688.6 KIR62929.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIR62929.1 - 0.25 11.9 0.0 0.34 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Prenyltrans PF00432.21 KIR62930.1 - 1e-12 47.5 0.2 1e-05 25.1 0.0 4.2 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KIR62930.1 - 6.4e-10 38.6 1.3 1.6e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KIR62930.1 - 2.3e-06 26.9 0.1 0.012 14.8 0.0 2.7 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KIR62930.1 - 0.033 13.2 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 A-macroglobulin TED domain CopD PF05425.13 KIR62931.1 - 0.0095 16.3 0.1 0.011 16.1 0.1 1.1 1 0 0 1 1 1 1 Copper resistance protein D Aldedh PF00171.22 KIR62932.1 - 1.7e-17 63.1 15.0 1.6e-13 50.0 10.0 2.1 1 1 0 2 2 2 2 Aldehyde dehydrogenase family AA_kinase PF00696.28 KIR62933.1 - 3.4e-39 134.9 2.8 3.4e-39 134.9 2.8 1.4 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 KIR62933.1 - 1.1e-16 60.5 0.2 3.8e-16 58.8 0.2 1.9 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 KIR62933.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.8 1 0 0 1 1 1 1 PUA-like domain DNA_binding_1 PF01035.20 KIR62934.1 - 1.3e-17 63.7 0.3 1.6e-17 63.4 0.3 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pyridoxal_deC PF00282.19 KIR62935.1 - 1.5e-15 56.8 0.0 5.3e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIR62935.1 - 7.4e-10 38.3 0.0 3e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIR62935.1 - 0.0027 17.1 5.5 0.0041 16.5 5.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DsrH PF04077.12 KIR62935.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 DsrH like protein Oxidored_q6 PF01058.22 KIR62936.1 - 4.7e-23 81.5 0.0 6.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF2252 PF10009.9 KIR62937.1 - 1.9e-111 372.9 2.4 2.2e-111 372.7 2.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.23 KIR62937.1 - 4.3e-05 23.6 6.0 0.0012 18.9 0.2 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family NAGLU_N PF12971.7 KIR62937.1 - 0.15 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Complex1_30kDa PF00329.19 KIR62938.1 - 6e-38 130.2 0.0 7.4e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Peptidase_S8 PF00082.22 KIR62939.1 - 3.6e-24 85.6 17.2 8.5e-24 84.3 17.2 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIR62939.1 - 3e-08 34.2 0.0 4.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 SnoaL PF07366.12 KIR62940.1 - 1.2e-24 86.5 0.0 1.7e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIR62940.1 - 1.6e-14 54.3 2.1 3.7e-14 53.2 2.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain Uma2 PF05685.12 KIR62941.1 - 8.4e-23 80.8 0.2 9.5e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease HrpB_C PF08482.10 KIR62941.1 - 0.14 12.6 0.1 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal Fer4 PF00037.27 KIR62942.1 - 1.6e-11 43.5 13.4 2.6e-09 36.5 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIR62942.1 - 2.8e-08 34.2 8.8 1.5e-07 31.9 9.6 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR62942.1 - 4.8e-07 29.8 3.6 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIR62942.1 - 5.8e-07 29.6 7.6 3.1e-06 27.3 8.5 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR62942.1 - 8.1e-06 26.7 18.8 0.0006 20.7 11.2 2.1 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KIR62942.1 - 2.1e-05 24.5 8.1 0.037 14.2 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIR62942.1 - 4.9e-05 23.2 9.7 0.001 19.1 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KIR62942.1 - 0.00021 21.7 10.2 0.00045 20.6 9.7 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR62942.1 - 0.00027 20.9 15.8 0.01 15.9 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIR62942.1 - 0.00032 21.2 10.5 0.0027 18.2 11.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KIR62942.1 - 0.067 13.9 11.6 0.99 10.2 0.6 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 KIR62942.1 - 0.078 14.0 4.2 0.078 14.0 4.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KIR62942.1 - 0.088 13.4 11.9 0.54 10.8 0.4 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I DUF3729 PF12526.8 KIR62942.1 - 0.19 13.3 6.2 0.43 12.2 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Fer4_4 PF12800.7 KIR62942.1 - 0.21 12.2 12.0 1.8 9.3 0.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Oxidored_q3 PF00499.20 KIR62943.1 - 4e-33 114.2 5.7 5.3e-33 113.8 5.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Oxidored_q2 PF00420.24 KIR62944.1 - 5.6e-23 80.6 7.1 7.7e-23 80.1 7.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2628 PF10947.8 KIR62944.1 - 7 7.1 7.4 13 6.2 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Proton_antipo_M PF00361.20 KIR62945.1 - 6.4e-77 258.6 14.9 1.2e-76 257.8 14.9 1.4 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 KIR62945.1 - 2.1e-09 37.3 0.1 1.1e-08 34.9 0.0 2.3 1 1 1 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 KIR62946.1 - 3.3e-70 236.6 15.1 5.2e-70 235.9 15.1 1.3 1 0 0 1 1 1 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 KIR62946.1 - 0.067 13.3 0.3 0.22 11.7 0.3 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 KIR62947.1 - 2.6e-45 154.9 12.7 2.6e-45 154.9 12.7 1.8 2 1 0 2 2 2 1 Proton-conducting membrane transporter Peptidase_M48 PF01435.18 KIR62948.1 - 3.9e-34 118.2 0.0 5.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KIR62948.1 - 0.025 13.8 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4010 PF13194.6 KIR62948.1 - 0.11 12.2 6.7 5 6.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) MFS_1 PF07690.16 KIR62949.1 - 2.6e-10 39.8 60.8 1.3e-07 30.9 30.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_sug_transp PF04142.15 KIR62949.1 - 2.1 7.4 4.8 3.2 6.8 2.5 2.1 1 1 1 2 2 2 0 Nucleotide-sugar transporter UPF0060 PF02694.15 KIR62950.1 - 3.7e-45 152.6 8.2 4.2e-45 152.4 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family DUF2157 PF09925.9 KIR62950.1 - 0.013 15.3 8.3 0.037 13.8 8.3 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) ArgJ PF01960.18 KIR62950.1 - 0.086 11.6 0.1 0.098 11.4 0.1 1.1 1 0 0 1 1 1 0 ArgJ family 7TMR-DISM_7TM PF07695.11 KIR62950.1 - 0.091 12.7 2.7 0.18 11.7 2.8 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling MerC PF03203.14 KIR62950.1 - 0.97 9.9 7.9 2 8.9 7.9 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein DUF520 PF04461.13 KIR62951.1 - 5.9e-63 211.8 1.7 6.6e-63 211.6 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) Med12-LCEWAV PF12145.8 KIR62951.1 - 0.012 14.5 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Flg_hook PF02120.16 KIR62951.1 - 0.015 15.1 2.1 0.69 9.8 0.1 2.6 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Acetyltransf_7 PF13508.7 KIR62954.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR62954.1 - 0.066 13.4 0.0 0.099 12.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GntR PF00392.21 KIR62955.1 - 1.7e-20 72.4 0.3 6.3e-20 70.6 0.3 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family UTRA PF07702.13 KIR62955.1 - 1.8e-18 66.7 0.3 2.4e-18 66.3 0.3 1.2 1 0 0 1 1 1 1 UTRA domain Rrf2 PF02082.20 KIR62955.1 - 7.2e-05 23.1 0.1 0.00022 21.5 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_41 PF14502.6 KIR62955.1 - 0.0037 16.9 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR62955.1 - 0.01 15.7 0.2 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 KIR62955.1 - 0.039 13.8 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_36 PF13730.6 KIR62955.1 - 0.044 13.7 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 KIR62955.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 KIR62955.1 - 0.15 12.0 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_31 PF13560.6 KIR62956.1 - 1.2e-13 51.1 0.4 1.2e-13 51.1 0.4 4.8 4 2 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR62956.1 - 3.2e-07 30.3 0.0 9.7e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR62956.1 - 8.5e-06 25.7 0.0 2.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR62956.1 - 0.0093 16.4 0.0 0.045 14.2 0.0 2.2 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain TPR_7 PF13176.6 KIR62956.1 - 4.5 7.5 7.1 12 6.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat EAL PF00563.20 KIR62957.1 - 1.3e-71 240.9 0.0 4e-71 239.3 0.0 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 KIR62957.1 - 1.2e-31 109.7 0.1 3.3e-31 108.2 0.0 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GAF PF01590.26 KIR62957.1 - 1.1e-10 42.3 0.4 3.7e-10 40.5 0.4 2.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KIR62957.1 - 9e-08 32.5 3.5 9.3e-08 32.5 0.7 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KIR62957.1 - 0.00017 22.0 1.2 0.0004 20.7 0.3 2.2 2 0 0 2 2 2 1 GAF domain Ribosomal_L33 PF00471.20 KIR62958.1 - 2.1e-23 82.5 3.3 2.3e-23 82.4 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 MaoC_dehydrat_N PF13452.6 KIR62959.1 - 2.3e-37 128.1 0.2 2.5e-37 127.9 0.2 1.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KIR62959.1 - 2.2e-06 27.2 0.1 3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydratas PF01575.19 KIR62960.1 - 3.8e-25 87.8 0.1 4.4e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIR62960.1 - 8.8e-06 25.9 0.0 1.2e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase PS-DH PF14765.6 KIR62960.1 - 0.0018 17.6 0.1 0.0022 17.3 0.1 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase NusG PF02357.19 KIR62961.1 - 1.6e-22 79.9 0.0 3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 KIR62961.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 KOW motif Ribosomal_L11_N PF03946.14 KIR62962.1 - 7.5e-29 99.4 0.1 1.3e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KIR62962.1 - 1e-27 96.4 0.6 1.7e-27 95.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L1 PF00687.21 KIR62963.1 - 5.5e-50 169.9 0.0 7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF4031 PF13223.6 KIR62963.1 - 0.11 12.7 0.4 2 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) ABC2_membrane_3 PF12698.7 KIR62964.1 - 3.4 6.7 4.1 4.4 6.3 4.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ribosomal_L10 PF00466.20 KIR62965.1 - 8e-25 86.9 0.0 1.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3182 PF11379.8 KIR62965.1 - 0.0054 15.7 0.1 0.0089 15.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3182) Ribosomal_L12 PF00542.19 KIR62966.1 - 8.2e-27 93.4 10.9 8.2e-27 93.4 10.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KIR62966.1 - 6.6e-19 67.4 9.1 1.1e-18 66.7 7.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 KIR62966.1 - 3.2 8.4 23.3 0.055 14.1 9.3 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein RNA_pol_Rpb2_6 PF00562.28 KIR62967.1 - 5.6e-159 529.4 0.0 2.7e-158 527.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 KIR62967.1 - 3e-29 102.0 0.0 4.8e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KIR62967.1 - 3.5e-29 100.8 0.0 8.1e-29 99.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KIR62967.1 - 1.6e-26 92.6 0.0 2.9e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 KIR62967.1 - 2e-26 92.0 0.2 2.6e-25 88.4 0.5 2.5 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_1 PF04563.15 KIR62967.1 - 1e-21 77.4 0.0 4.9e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb1_1 PF04997.12 KIR62968.1 - 1.9e-83 280.4 0.0 3.8e-83 279.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIR62968.1 - 6.3e-66 222.5 0.4 2.5e-64 217.3 0.4 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIR62968.1 - 1.2e-38 133.0 0.0 9.2e-28 97.5 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIR62968.1 - 1.8e-23 83.2 0.0 3.7e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KIR62968.1 - 7.5e-11 41.9 0.0 2.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Cluap1 PF10234.9 KIR62968.1 - 0.54 9.6 4.7 0.91 8.9 4.7 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 CdvA PF18822.1 KIR62968.1 - 9.3 6.1 11.6 7.8 6.3 0.9 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Ribosom_S12_S23 PF00164.25 KIR62969.1 - 1.7e-42 143.6 2.7 2e-42 143.4 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KIR62969.1 - 0.18 12.6 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S12 Ribosomal_S7 PF00177.21 KIR62970.1 - 1.2e-58 197.0 0.2 1.3e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GTP_EFTU PF00009.27 KIR62971.1 - 2.4e-67 226.2 0.1 3.8e-67 225.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIR62971.1 - 2.4e-46 156.5 0.0 5e-46 155.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KIR62971.1 - 1e-35 121.7 0.1 2.3e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KIR62971.1 - 3.7e-30 103.8 0.1 9.9e-30 102.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIR62971.1 - 9.1e-17 61.2 1.0 3.6e-16 59.3 1.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KIR62971.1 - 9.7e-08 31.9 0.1 2e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KIR62971.1 - 0.0012 18.9 0.1 0.0044 17.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIR62971.1 - 0.0026 17.1 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family ATP-grasp_4 PF13535.6 KIR62971.1 - 0.0062 16.1 0.4 0.015 14.9 0.4 1.5 1 0 0 1 1 1 1 ATP-grasp domain GTP_EFTU_D4 PF14578.6 KIR62971.1 - 0.016 15.1 0.1 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 AvrPtoB_bdg PF16847.5 KIR62971.1 - 0.13 12.8 0.0 0.91 10.0 0.0 2.3 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain GTP_EFTU PF00009.27 KIR62972.1 - 4.5e-56 189.5 0.0 6.2e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIR62972.1 - 4.2e-33 114.0 0.2 8.2e-33 113.1 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIR62972.1 - 3e-16 59.6 4.2 6.4e-16 58.5 3.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIR62972.1 - 2.3e-05 24.5 0.1 5.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ribosomal_S10 PF00338.22 KIR62973.1 - 3.5e-37 126.6 0.1 3.8e-37 126.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 KIR62973.1 - 0.13 13.1 0.0 0.65 10.9 0.0 1.8 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Ribosomal_L3 PF00297.22 KIR62974.1 - 1.8e-17 63.4 7.5 5.3e-15 55.3 2.5 2.9 2 1 1 3 3 3 2 Ribosomal protein L3 Ribosomal_L4 PF00573.22 KIR62975.1 - 9.2e-63 211.4 0.6 1.1e-62 211.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2336 PF10098.9 KIR62975.1 - 0.0089 15.5 0.2 0.037 13.5 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2336) Ribosomal_L23 PF00276.20 KIR62976.1 - 1.7e-30 105.2 0.5 1.9e-30 105.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 DUF2396 PF09654.10 KIR62976.1 - 0.056 13.5 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Ribosomal_L2_C PF03947.18 KIR62977.1 - 7.6e-53 178.0 3.9 7.6e-53 178.0 3.9 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIR62977.1 - 1.1e-33 115.0 1.0 2.1e-33 114.1 1.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S19 PF00203.21 KIR62978.1 - 2.1e-36 123.7 0.3 2.3e-36 123.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.19 KIR62979.1 - 1.5e-34 118.3 0.2 2e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 KIR62980.1 - 5.8e-35 119.7 0.7 1.4e-34 118.5 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KIR62980.1 - 6.6e-20 70.7 3.8 1.1e-19 70.1 3.8 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIR62980.1 - 0.00094 19.0 0.6 0.002 17.9 0.6 1.6 1 0 0 1 1 1 1 KH domain Ribosomal_L16 PF00252.18 KIR62981.1 - 3.5e-45 153.2 0.2 4e-45 153.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L29 PF00831.23 KIR62982.1 - 1.3e-23 82.7 6.0 1.5e-23 82.5 6.0 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein CCDC85 PF10226.9 KIR62982.1 - 0.00012 21.9 1.9 0.00013 21.7 1.9 1.1 1 0 0 1 1 1 1 CCDC85 family DUF1192 PF06698.11 KIR62982.1 - 3.9 7.6 7.9 7.2 6.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Ribosomal_S17 PF00366.20 KIR62983.1 - 1.7e-31 108.1 0.5 2.2e-31 107.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 KIR62984.1 - 1.9e-54 183.0 0.2 2e-54 182.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L5_C PF00673.21 KIR62985.1 - 1.3e-37 127.9 0.0 1.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KIR62985.1 - 8.9e-28 96.4 0.3 1.4e-27 95.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S14 PF00253.21 KIR62986.1 - 8.2e-25 86.3 3.5 9.4e-25 86.1 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e HTH_17 PF12728.7 KIR62986.1 - 0.045 13.9 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_lid_5 PF17865.1 KIR62986.1 - 0.2 11.7 0.1 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 Midasin AAA lid domain Ribosomal_S8 PF00410.19 KIR62987.1 - 6.1e-49 165.2 0.0 6.9e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 KIR62988.1 - 1.5e-41 140.9 1.3 4.3e-20 72.2 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 TubC_N PF18563.1 KIR62988.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 1 1 1 2 2 2 0 TubC N-terminal docking domain Ribosomal_S5_C PF03719.15 KIR62989.1 - 1.2e-29 101.6 0.5 1.8e-29 101.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KIR62989.1 - 1.3e-27 95.5 3.2 2.2e-27 94.8 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L30 PF00327.20 KIR62990.1 - 1e-19 70.2 0.3 1.1e-19 70.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 KIR62991.1 - 1.6e-31 109.6 3.7 2e-31 109.3 3.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 KIR62991.1 - 0.2 11.1 1.8 0.27 10.6 0.0 2.1 3 0 0 3 3 3 0 Ribosomal protein 60S L18 and 50S L18e SecY PF00344.20 KIR62992.1 - 9e-116 386.4 13.0 1.1e-115 386.2 13.0 1.1 1 0 0 1 1 1 1 SecY translocase ADK PF00406.22 KIR62993.1 - 4.1e-55 186.0 0.0 4.8e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIR62993.1 - 1.8e-26 93.2 0.0 4.4e-26 91.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KIR62993.1 - 2.9e-12 46.4 1.8 4.6e-12 45.7 1.8 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIR62993.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR62993.1 - 0.00089 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KIR62993.1 - 0.0047 16.7 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 KIR62993.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1451 PF07295.11 KIR62993.1 - 0.058 13.4 0.3 0.096 12.7 0.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain RuvB_N PF05496.12 KIR62993.1 - 0.068 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 KIR62993.1 - 0.15 11.7 0.0 0.75 9.4 0.0 2.1 3 0 0 3 3 3 0 Thymidylate kinase TF_Zn_Ribbon PF08271.12 KIR62993.1 - 0.17 11.5 0.6 0.37 10.4 0.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KIR62993.1 - 0.23 11.4 0.9 0.39 10.7 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Peptidase_M24 PF00557.24 KIR62994.1 - 3.5e-42 144.5 0.9 4.1e-42 144.2 0.9 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 eIF-1a PF01176.19 KIR62995.1 - 2.4e-29 100.9 0.1 2.7e-29 100.8 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L36 PF00444.18 KIR62996.1 - 6.5e-18 64.7 12.2 6.9e-18 64.6 12.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_S13 PF00416.22 KIR62997.1 - 9.4e-34 116.6 3.7 4.5e-32 111.1 3.7 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 KIR62997.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Ribosomal_S11 PF00411.19 KIR62998.1 - 4.8e-48 162.1 0.9 6.5e-48 161.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 ELFV_dehydrog PF00208.21 KIR62998.1 - 0.036 13.8 0.2 6.7 6.4 0.0 2.0 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_S4 PF00163.19 KIR62999.1 - 2.5e-29 102.0 2.3 4.4e-29 101.2 2.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KIR62999.1 - 3.9e-21 74.5 0.2 7e-21 73.7 0.2 1.4 1 0 0 1 1 1 1 S4 domain GDA1_CD39 PF01150.17 KIR62999.1 - 0.017 13.8 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF2785 PF10978.8 KIR62999.1 - 0.075 12.8 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2785) RNA_pol_A_CTD PF03118.15 KIR63000.1 - 1.5e-25 88.7 0.0 3.2e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 KIR63000.1 - 2e-23 82.9 0.0 3.6e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIR63000.1 - 4e-18 64.6 0.0 6.1e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HHH_5 PF14520.6 KIR63000.1 - 0.0035 17.9 0.2 0.5 11.0 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain Ribosomal_L17 PF01196.19 KIR63001.1 - 8.7e-37 125.9 0.1 1.5e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 PseudoU_synth_1 PF01416.20 KIR63002.1 - 1e-27 96.7 0.0 3e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase ABC_tran PF00005.27 KIR63004.1 - 1.6e-31 109.7 0.0 8.1e-17 62.0 0.0 3.1 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KIR63004.1 - 7.1e-17 62.2 3.3 0.0012 18.7 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR63004.1 - 1.7e-08 34.2 0.0 0.063 12.7 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KIR63004.1 - 1.8e-05 24.7 0.5 0.27 11.2 0.1 3.6 4 0 0 4 4 4 2 NACHT domain AAA_29 PF13555.6 KIR63004.1 - 9.5e-05 22.1 0.0 0.044 13.5 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR63004.1 - 0.00012 22.4 0.2 0.22 11.8 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIR63004.1 - 0.00016 22.1 7.9 0.0085 16.5 0.7 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KIR63004.1 - 0.00026 20.8 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIR63004.1 - 0.00037 20.8 4.0 0.44 10.8 0.4 3.4 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KIR63004.1 - 0.00041 20.5 0.7 0.2 11.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR63004.1 - 0.00045 20.8 0.0 0.026 15.0 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KIR63004.1 - 0.0014 19.1 0.2 0.044 14.2 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KIR63004.1 - 0.002 18.7 0.7 4.2 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 KIR63004.1 - 0.0022 18.0 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KIR63004.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIR63004.1 - 0.0038 17.2 0.0 0.097 12.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KIR63004.1 - 0.0046 17.0 0.4 1.5 8.9 0.1 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KIR63004.1 - 0.006 16.2 3.5 0.79 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran_Xtn PF12848.7 KIR63004.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_15 PF13175.6 KIR63004.1 - 0.022 14.5 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KIR63004.1 - 0.029 14.1 6.0 0.79 9.4 0.3 3.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KIR63004.1 - 0.037 14.3 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KIR63004.1 - 0.037 13.8 0.2 11 5.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Tox-GHH PF15636.6 KIR63004.1 - 0.044 13.8 1.2 0.11 12.5 1.2 1.6 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin RNA_helicase PF00910.22 KIR63004.1 - 0.075 13.4 0.1 16 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF3584 PF12128.8 KIR63004.1 - 0.12 9.8 3.7 0.21 9.1 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.12 KIR63004.1 - 0.14 11.4 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 KIR63004.1 - 0.15 12.0 1.9 5.3 7.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIR63004.1 - 0.18 11.3 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KIR63004.1 - 0.22 10.5 1.6 0.47 9.4 0.8 1.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KIR63004.1 - 0.26 10.8 1.3 0.5 9.9 0.1 2.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Aldo_ket_red PF00248.21 KIR63005.1 - 1.3e-66 224.8 0.0 1.4e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2914 PF11141.8 KIR63006.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF756 PF05506.12 KIR63006.1 - 0.074 14.0 0.8 1.4 9.9 0.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF756) ThuA PF06283.11 KIR63007.1 - 5.7e-85 284.8 1.9 1.2e-84 283.8 1.9 1.6 1 0 0 1 1 1 1 Trehalose utilisation GSDH PF07995.11 KIR63007.1 - 1.4e-43 149.5 0.1 8.4e-41 140.4 0.1 2.4 2 0 0 2 2 2 2 Glucose / Sorbosone dehydrogenase DUF1349 PF07081.11 KIR63007.1 - 3.8e-31 108.2 0.0 6.7e-18 65.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 KIR63007.1 - 1.6e-28 99.8 0.0 1.8e-14 53.9 0.0 3.0 3 0 0 3 3 3 2 Beta xylosidase C-terminal Concanavalin A-like domain PKD PF00801.20 KIR63007.1 - 3e-26 91.0 36.0 4.4e-16 58.5 2.5 5.9 5 0 0 5 5 4 3 PKD domain CBM_6 PF03422.15 KIR63007.1 - 3.6e-21 75.7 0.8 3.6e-21 75.7 0.8 7.3 7 2 2 9 9 7 2 Carbohydrate binding module (family 6) CHB_HEX_C PF03174.13 KIR63007.1 - 8.5e-06 25.7 1.2 0.013 15.4 0.1 3.2 3 0 0 3 3 2 2 Chitobiase/beta-hexosaminidase C-terminal domain DUF5010_C PF18099.1 KIR63007.1 - 3.2e-05 24.0 0.2 0.00031 20.8 0.2 2.8 1 0 0 1 1 1 1 DUF5010 C-terminal domain HYR PF02494.16 KIR63007.1 - 8.5e-05 22.8 1.0 0.54 10.6 0.0 4.7 3 0 0 3 3 3 1 HYR domain DUF4625 PF15418.6 KIR63007.1 - 0.00052 20.3 1.1 20 5.4 0.0 5.3 5 1 1 6 6 6 0 Domain of unknown function (DUF4625) Big_3_2 PF12245.8 KIR63007.1 - 0.00059 20.1 4.7 9.1 6.6 0.1 6.1 6 1 1 7 7 5 1 Bacterial Ig-like domain Big_3_3 PF13750.6 KIR63007.1 - 0.0029 17.3 3.8 6.7 6.3 0.1 4.6 3 1 1 4 4 4 1 Bacterial Ig-like domain (group 3) DUF4399 PF14347.6 KIR63007.1 - 0.051 14.0 0.1 8.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4399) PKD_3 PF16820.5 KIR63007.1 - 0.078 12.7 3.6 1.9 8.3 0.1 3.0 3 0 0 3 3 3 0 PKD-like domain Cadherin PF00028.17 KIR63007.1 - 0.23 11.9 0.9 17 6.0 0.0 4.1 3 0 0 3 3 3 0 Cadherin domain BiPBP_C PF06832.12 KIR63007.1 - 0.28 11.3 9.0 44 4.2 0.0 6.4 8 1 1 9 9 9 0 Penicillin-Binding Protein C-terminus Family DUF1905 PF08922.11 KIR63007.1 - 0.28 11.3 2.1 52 4.0 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1905) TMP-TENI PF02581.17 KIR63008.1 - 3.1e-45 153.7 1.7 3.6e-45 153.5 1.7 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase DUF561 PF04481.12 KIR63008.1 - 0.36 10.0 0.7 0.61 9.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DAO PF01266.24 KIR63009.1 - 2.8e-61 208.1 13.6 3.2e-61 207.9 13.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR63009.1 - 4.5e-05 23.6 1.3 0.00013 22.1 1.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR63009.1 - 0.00038 19.7 2.9 0.00038 19.7 2.9 1.7 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KIR63009.1 - 0.0078 16.1 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR63009.1 - 0.033 13.6 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIR63009.1 - 0.042 12.5 2.1 0.072 11.8 2.1 1.4 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 KIR63009.1 - 0.056 13.9 0.7 0.66 10.5 0.2 2.9 2 1 1 3 3 3 0 XdhC Rossmann domain Pyr_redox PF00070.27 KIR63009.1 - 0.071 13.7 0.8 0.23 12.0 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIR63009.1 - 0.092 13.2 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF3040 PF11239.8 KIR63009.1 - 0.19 12.0 2.9 0.44 10.9 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) NAD_binding_9 PF13454.6 KIR63009.1 - 0.37 10.8 3.3 0.16 12.0 0.6 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIR63009.1 - 1.4 7.9 5.5 0.2 10.6 1.6 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KIR63009.1 - 2 7.4 3.4 2.9 6.9 3.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiS PF02597.20 KIR63010.1 - 4.6e-14 52.8 0.3 5.4e-14 52.6 0.3 1.0 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 KIR63010.1 - 0.037 14.1 0.3 0.14 12.2 0.3 1.9 1 1 0 1 1 1 0 TGS domain Fer2_4 PF13510.6 KIR63010.1 - 0.13 12.3 0.3 0.36 10.9 0.2 1.8 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain ThiG PF05690.14 KIR63011.1 - 1.5e-108 361.8 0.8 1.7e-108 361.6 0.8 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 KIR63011.1 - 4.7e-05 22.6 0.2 0.00072 18.7 0.1 2.0 1 1 1 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KIR63011.1 - 0.00027 20.5 0.1 0.00073 19.1 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 KIR63011.1 - 0.012 14.8 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KIR63011.1 - 0.014 14.4 0.4 0.021 13.8 0.4 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 KIR63011.1 - 0.018 14.2 0.3 0.083 12.1 0.1 2.0 1 1 2 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.17 KIR63011.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 SOR/SNZ family LDcluster4 PF18306.1 KIR63011.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family NMO PF03060.15 KIR63011.1 - 0.2 11.0 2.5 0.3 10.4 2.5 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Phos_pyr_kin PF08543.12 KIR63012.1 - 1.7e-80 270.0 0.9 1.9e-80 269.8 0.9 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KIR63012.1 - 5e-15 55.6 3.4 7.2e-15 55.1 3.4 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ThiC_Rad_SAM PF01964.18 KIR63013.1 - 1.5e-200 666.3 0.0 1.8e-200 666.1 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 KIR63013.1 - 1.1e-14 53.9 0.0 3.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 ThiC-associated domain CBP_BcsR PF10945.8 KIR63014.1 - 0.26 10.8 1.5 0.34 10.4 0.4 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR Cupin_2 PF07883.11 KIR63015.1 - 2e-05 24.2 0.3 3e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 KIR63015.1 - 0.00026 20.9 0.0 0.00029 20.7 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Auxin_BP PF02041.16 KIR63015.1 - 0.019 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein PCO_ADO PF07847.12 KIR63015.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.2 1 1 0 1 1 1 0 PCO_ADO Bac_luciferase PF00296.20 KIR63016.1 - 4.1e-52 177.6 12.0 2.1e-51 175.2 9.7 1.9 1 1 1 2 2 2 2 Luciferase-like monooxygenase ABC_tran PF00005.27 KIR63017.1 - 6.6e-32 110.9 0.0 9.3e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR63017.1 - 1.5e-07 31.5 0.1 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR63017.1 - 7.6e-05 23.1 0.2 0.00013 22.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KIR63017.1 - 0.0018 18.3 0.0 0.0057 16.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR63017.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIR63017.1 - 0.0025 18.1 0.0 0.0047 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR63017.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KIR63017.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 KIR63017.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIR63017.1 - 0.04 13.5 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIR63017.1 - 0.063 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KIR63017.1 - 0.11 12.2 0.4 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIR63017.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ATPase_2 PF01637.18 KIR63017.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIR63017.1 - 0.18 12.2 0.0 0.73 10.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KIR63017.1 - 0.21 11.0 0.0 3.1 7.2 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR63017.1 - 0.32 11.4 0.0 0.48 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NMT1 PF09084.11 KIR63018.1 - 6.9e-40 137.3 0.7 9.7e-40 136.8 0.7 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KIR63018.1 - 3.7e-12 46.5 0.7 8.2e-12 45.4 0.7 1.5 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 KIR63018.1 - 3.3e-05 23.6 0.1 4.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein VitK2_biosynth PF02621.14 KIR63018.1 - 0.075 12.5 0.1 0.68 9.4 0.1 2.0 1 1 1 2 2 2 0 Menaquinone biosynthesis Peripla_BP_6 PF13458.6 KIR63019.1 - 2e-42 146.1 6.9 2.4e-42 145.9 6.9 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KIR63019.1 - 2.1e-27 96.2 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KIR63019.1 - 8.9e-09 34.8 0.0 0.00015 20.9 0.1 3.0 3 0 0 3 3 3 2 Periplasmic binding protein domain LppC PF04348.13 KIR63019.1 - 0.00032 19.6 1.1 0.00043 19.2 1.1 1.2 1 0 0 1 1 1 1 LppC putative lipoprotein NIT PF08376.10 KIR63020.1 - 9.9e-26 91.6 20.2 9.9e-26 91.6 20.2 2.3 2 1 0 2 2 2 1 Nitrate and nitrite sensing HATPase_c PF02518.26 KIR63020.1 - 3.3e-08 34.0 0.0 6.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR63020.1 - 2.2e-06 28.0 1.6 1.4e-05 25.4 0.6 2.9 2 1 0 2 2 2 1 HAMP domain FumaraseC_C PF10415.9 KIR63020.1 - 0.15 12.5 0.5 4.4 7.8 0.2 2.9 2 0 0 2 2 2 0 Fumarase C C-terminus Robl_LC7 PF03259.17 KIR63021.1 - 3.2e-23 81.3 0.4 4.4e-23 80.9 0.4 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF742 PF05331.11 KIR63022.1 - 3.2e-28 97.8 0.7 3.6e-28 97.6 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_IclR PF09339.10 KIR63022.1 - 0.011 15.5 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain ATP_bind_1 PF03029.17 KIR63023.1 - 2.1e-28 99.7 0.7 5.6e-27 95.1 0.7 2.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KIR63023.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIR63023.1 - 0.0025 17.7 0.0 0.13 12.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 KIR63023.1 - 0.0057 16.3 0.3 0.069 12.7 0.3 2.4 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 KIR63023.1 - 0.023 14.3 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KIR63023.1 - 0.039 14.2 0.2 0.53 10.5 0.4 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIR63023.1 - 0.039 14.3 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KIR63023.1 - 0.048 12.7 0.5 0.067 12.2 0.5 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIR63023.1 - 0.055 13.5 0.1 0.085 12.9 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KIR63023.1 - 0.18 11.5 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIR63023.1 - 0.31 11.3 1.4 0.63 10.3 1.4 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIR63023.1 - 0.78 9.6 2.8 0.49 10.3 0.9 1.6 2 0 0 2 2 2 0 NTPase HEM4 PF02602.15 KIR63024.1 - 4.1e-38 131.0 0.5 5.6e-38 130.6 0.5 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Trans_reg_C PF00486.28 KIR63024.1 - 4e-11 42.8 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DinB_2 PF12867.7 KIR63024.1 - 0.012 16.1 1.2 0.046 14.2 0.8 2.1 1 1 0 1 1 1 0 DinB superfamily Molybdopterin PF00384.22 KIR63025.1 - 1.1e-71 242.1 0.0 1.3e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KIR63025.1 - 6.6e-35 119.5 0.0 1.2e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain MFS_1 PF07690.16 KIR63027.1 - 7.6e-18 64.6 84.3 2.4e-15 56.4 44.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4271 PF14093.6 KIR63027.1 - 0.0041 17.1 1.4 1.5 8.7 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4271) Ribosomal_L13 PF00572.18 KIR63028.1 - 7.2e-57 191.0 0.1 8.3e-57 190.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 KIR63029.1 - 6.2e-43 146.2 0.2 7.2e-43 146.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PGM_PMM_I PF02878.16 KIR63030.1 - 9.8e-42 141.9 1.0 1.4e-41 141.4 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIR63030.1 - 2.8e-31 108.1 3.0 9e-31 106.4 1.0 2.5 2 1 1 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIR63030.1 - 1.5e-19 70.6 1.0 4.1e-19 69.1 1.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIR63030.1 - 2.5e-15 56.4 3.3 9.7e-15 54.5 3.3 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AlaDh_PNT_N PF05222.15 KIR63030.1 - 0.033 14.5 2.0 0.052 13.9 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain CinA_KH PF18146.1 KIR63030.1 - 0.079 13.1 1.4 0.33 11.1 1.4 2.1 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain FtsX PF02687.21 KIR63031.1 - 1.6e-05 25.3 19.4 4e-05 24.0 4.2 5.1 5 1 0 5 5 5 2 FtsX-like permease family MacB_PCD PF12704.7 KIR63031.1 - 8.3 6.7 15.3 0.42 11.0 3.4 3.3 4 0 0 4 4 4 0 MacB-like periplasmic core domain Aminotran_1_2 PF00155.21 KIR63032.1 - 7.9e-62 209.5 0.0 8.9e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR63032.1 - 6.6e-07 28.2 0.0 1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIR63032.1 - 1.4e-06 27.5 0.0 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIR63032.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase ScsC_N PF18312.1 KIR63032.1 - 0.2 11.5 0.2 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain OKR_DC_1 PF01276.20 KIR63032.1 - 0.26 10.0 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain SIS PF01380.22 KIR63033.1 - 1.6e-61 205.9 0.0 5.2e-35 120.2 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KIR63033.1 - 6.4e-21 74.9 0.1 1.5e-20 73.8 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIR63033.1 - 3.2e-13 49.7 0.0 6.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 KIR63033.1 - 0.015 15.3 0.1 0.094 12.7 0.0 2.3 2 0 0 2 2 2 0 SIS domain GATase_4 PF13230.6 KIR63033.1 - 0.025 13.5 0.0 0.064 12.1 0.0 1.6 2 0 0 2 2 2 0 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 KIR63033.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain T7SS_ESX_EspC PF10824.8 KIR63034.1 - 0.00013 22.4 1.4 0.00038 20.9 1.4 1.7 1 1 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm Carb_kinase PF01256.17 KIR63035.1 - 1.6e-51 175.1 4.1 3e-51 174.3 4.1 1.4 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 KIR63035.1 - 7.7e-32 110.5 3.4 7.7e-32 110.5 3.4 1.9 2 1 1 3 3 3 1 YjeF-related protein N-terminus Phos_pyr_kin PF08543.12 KIR63035.1 - 0.00034 20.1 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KIR63035.1 - 0.0088 15.4 0.7 0.014 14.8 0.7 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ala_racemase_N PF01168.20 KIR63036.1 - 2.9e-63 213.4 0.3 3.8e-63 213.1 0.3 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 KIR63036.1 - 1.6e-42 144.2 0.1 3e-42 143.3 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Abhydrolase_6 PF12697.7 KIR63037.1 - 3.6e-26 93.2 4.6 3.6e-26 93.2 4.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR63037.1 - 3e-25 89.3 0.0 4.4e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR63037.1 - 2.8e-20 72.6 1.2 1.9e-19 69.9 1.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIR63037.1 - 7.2e-06 26.3 0.0 4.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_4 PF08386.10 KIR63037.1 - 9.2e-06 25.7 0.1 0.00023 21.2 0.0 2.7 3 1 0 3 3 3 1 TAP-like protein Ndr PF03096.14 KIR63037.1 - 1.2e-05 24.2 0.0 7.8e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.21 KIR63037.1 - 3.2e-05 23.5 0.1 0.089 12.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KIR63037.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KIR63037.1 - 0.002 17.9 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KIR63037.1 - 0.002 17.8 0.0 0.0056 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 KIR63037.1 - 0.0022 17.9 0.0 0.071 13.0 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_8 PF06259.12 KIR63037.1 - 0.028 14.1 0.2 0.85 9.2 0.0 2.5 1 1 1 2 2 2 0 Alpha/beta hydrolase PGAP1 PF07819.13 KIR63037.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KIR63037.1 - 0.15 12.0 0.4 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) DUF915 PF06028.11 KIR63037.1 - 0.18 11.1 0.1 0.36 10.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) UDG PF03167.19 KIR63038.1 - 1.1e-20 74.2 0.0 1.5e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MDMPI_N PF11716.8 KIR63039.1 - 3.7e-10 40.6 9.6 3.7e-10 40.6 9.6 1.7 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 KIR63039.1 - 0.016 16.0 1.8 0.016 16.0 1.8 3.0 2 2 0 2 2 2 0 MDMPI C-terminal domain DinB_2 PF12867.7 KIR63039.1 - 0.024 15.1 7.2 0.071 13.6 7.2 1.8 1 1 0 1 1 1 0 DinB superfamily DUF2249 PF10006.9 KIR63039.1 - 0.026 14.4 0.5 4.6 7.2 0.1 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2249) SCP2 PF02036.17 KIR63039.1 - 0.044 14.3 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 SCP-2 sterol transfer family Peptidase_M22 PF00814.25 KIR63040.1 - 3.2e-23 82.8 2.7 5.6e-23 82.0 2.7 1.5 1 1 0 1 1 1 1 Glycoprotease family 5TM-5TMR_LYT PF07694.12 KIR63040.1 - 0.35 10.4 2.4 0.56 9.7 2.4 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Peptidase_M22 PF00814.25 KIR63041.1 - 1.5e-92 310.1 2.7 1.8e-92 309.9 2.7 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KIR63041.1 - 0.0001 22.1 0.0 0.0033 17.1 0.0 2.1 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus FGGY_C PF02782.16 KIR63041.1 - 0.0095 15.7 0.9 0.022 14.5 0.9 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4142 PF13628.6 KIR63043.1 - 2.8e-17 63.3 0.1 3.7e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) TPP_enzyme_M PF00205.22 KIR63043.1 - 0.083 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain SNN_transmemb PF09049.10 KIR63043.1 - 4.9 7.2 7.1 1.1 9.2 1.0 2.6 2 0 0 2 2 2 0 Stannin transmembrane ROK PF00480.20 KIR63044.1 - 2.8e-48 164.9 0.2 3.6e-48 164.5 0.2 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR63044.1 - 0.0091 15.9 3.6 0.018 14.9 0.3 2.8 3 0 0 3 3 3 1 MarR family MarR PF01047.22 KIR63044.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 MarR family TFIIE_alpha PF02002.17 KIR63044.1 - 0.056 13.3 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit BPD_transp_2 PF02653.16 KIR63045.1 - 4.4e-42 144.1 49.0 1e-41 142.9 49.0 1.7 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 KIR63046.1 - 1.5e-29 103.3 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR63046.1 - 2e-10 41.0 0.2 0.00013 21.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR63046.1 - 4.7e-07 29.5 0.3 0.016 14.6 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIR63046.1 - 1.1e-06 28.5 0.2 4.9e-06 26.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR63046.1 - 0.00027 20.6 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR63046.1 - 0.00033 21.2 0.0 0.00053 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KIR63046.1 - 0.00062 18.7 1.1 1.2 7.8 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 KIR63046.1 - 0.00099 18.7 0.9 0.013 15.1 0.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR63046.1 - 0.0061 16.9 0.1 0.017 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR63046.1 - 0.0097 15.8 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIR63046.1 - 0.013 15.8 0.7 0.29 11.4 0.7 2.2 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIR63046.1 - 0.035 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 KIR63046.1 - 0.037 14.3 0.2 0.44 10.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.7 KIR63046.1 - 0.044 12.7 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.13 KIR63046.1 - 0.069 12.3 0.0 0.29 10.2 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) TsaE PF02367.17 KIR63046.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA_edit PF04073.15 KIR63047.1 - 6.4e-28 97.3 0.5 7.3e-28 97.1 0.5 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Thump_like PF18096.1 KIR63048.1 - 1e-23 83.0 5.1 4.6e-23 80.9 0.9 2.7 3 0 0 3 3 3 1 THUMP domain-like Methyltransf_11 PF08241.12 KIR63048.1 - 9.5e-07 29.4 0.6 2.4e-06 28.1 0.6 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR63048.1 - 2.1e-06 28.4 0.7 6.3e-06 26.8 0.7 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR63048.1 - 9.7e-05 22.2 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KIR63048.1 - 0.00071 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KIR63048.1 - 0.001 18.6 4.1 0.0018 17.7 1.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KIR63048.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KIR63048.1 - 0.014 15.0 0.2 0.021 14.3 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KIR63048.1 - 0.093 13.5 0.4 0.45 11.3 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIR63048.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KIR63048.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SAM_MT PF04445.13 KIR63048.1 - 0.49 9.8 2.1 0.82 9.1 2.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Cpn60_TCP1 PF00118.24 KIR63049.1 - 5.3e-92 309.0 12.6 8.5e-92 308.3 12.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FlgM PF04316.13 KIR63049.1 - 0.073 13.4 2.4 0.29 11.5 0.2 2.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM CbiA PF01656.23 KIR63049.1 - 0.15 12.1 0.3 0.61 10.2 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Oxidored_molyb PF00174.19 KIR63050.1 - 6.2e-39 133.4 0.0 9e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Big_7 PF17957.1 KIR63050.1 - 9.6e-07 29.5 0.3 4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial Ig domain Mo-co_dimer PF03404.16 KIR63050.1 - 0.0037 17.3 1.2 0.01 15.9 1.2 1.7 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain CBM_6 PF03422.15 KIR63050.1 - 0.033 14.5 0.5 0.061 13.6 0.5 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SoxZ PF08770.11 KIR63050.1 - 0.064 13.0 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ DUF4131 PF13567.6 KIR63050.1 - 3 7.5 14.6 62 3.2 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) GerE PF00196.19 KIR63051.1 - 2.6e-19 68.5 0.0 4.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR63051.1 - 4.6e-05 23.0 0.1 0.00012 21.7 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR63051.1 - 0.00013 21.4 0.1 0.00083 18.8 0.2 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR63051.1 - 0.0012 18.6 0.1 0.0049 16.6 0.1 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KIR63051.1 - 0.0099 15.6 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR63051.1 - 0.016 15.0 0.5 0.24 11.3 0.0 2.9 2 1 1 3 3 3 0 AsnC-type helix-turn-helix domain Response_reg PF00072.24 KIR63051.1 - 0.029 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Response regulator receiver domain CoA_binding_2 PF13380.6 KIR63051.1 - 0.17 12.4 1.1 0.22 12.0 0.3 1.7 2 0 0 2 2 2 0 CoA binding domain DUF5319 PF17252.2 KIR63052.1 - 2.4e-49 166.6 1.8 2.7e-49 166.4 1.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5319) IMPDH PF00478.25 KIR63053.1 - 6e-159 528.6 5.5 6.9e-159 528.4 5.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KIR63053.1 - 3.6e-19 68.9 2.1 2.8e-09 37.3 0.2 2.8 3 0 0 3 3 2 2 CBS domain NMO PF03060.15 KIR63053.1 - 1.2e-10 41.4 8.9 1e-06 28.4 8.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KIR63053.1 - 2.3e-05 24.0 3.9 0.054 12.9 0.1 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 KIR63053.1 - 3.6e-05 22.9 13.5 3.6e-05 22.9 13.5 2.8 3 1 1 4 4 4 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KIR63053.1 - 0.018 14.2 10.7 0.016 14.3 9.5 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase CoA_binding_2 PF13380.6 KIR63053.1 - 0.068 13.7 0.7 0.25 11.8 0.6 2.0 3 0 0 3 3 2 0 CoA binding domain DUF374 PF04028.13 KIR63053.1 - 0.082 12.5 0.1 0.26 10.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF374) ThiG PF05690.14 KIR63053.1 - 0.098 11.9 10.4 0.17 11.2 4.5 2.7 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.6 KIR63053.1 - 0.1 12.1 5.1 0.034 13.6 1.8 1.9 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase NAD_binding_7 PF13241.6 KIR63053.1 - 0.32 11.5 2.8 1.3 9.5 2.8 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding NanE PF04131.14 KIR63053.1 - 0.6 9.3 6.2 1.7 7.8 0.7 3.0 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 KIR63053.1 - 1.6 7.9 7.5 0.28 10.4 1.5 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase IMPDH PF00478.25 KIR63054.1 - 6.8e-34 117.4 0.3 1.1e-31 110.1 0.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIR63054.1 - 8.3e-10 38.2 3.0 1.7e-09 37.2 2.6 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KIR63054.1 - 2.7e-05 23.5 2.5 4.8e-05 22.7 1.4 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 KIR63054.1 - 0.013 14.9 8.3 0.18 11.2 0.8 2.6 2 1 1 3 3 3 0 Nitronate monooxygenase ThiG PF05690.14 KIR63054.1 - 0.07 12.4 6.6 1.9 7.7 1.5 2.6 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG NanE PF04131.14 KIR63054.1 - 0.14 11.3 0.7 9.4 5.4 0.0 2.7 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Peptidase_M1 PF01433.20 KIR63055.1 - 2.3e-26 92.7 0.3 5e-26 91.6 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIR63055.1 - 1.1e-12 48.5 0.0 2.3e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF4157 PF13699.6 KIR63055.1 - 0.15 12.3 0.4 30 4.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4157) Peptidase_M61 PF05299.12 KIR63055.1 - 0.15 12.4 2.4 6.7 7.2 2.4 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase HTH_1 PF00126.27 KIR63056.1 - 2.5e-22 78.6 2.3 2.5e-22 78.6 2.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 KIR63056.1 - 6.8e-16 58.3 9.5 6.8e-16 58.3 9.5 2.6 2 1 0 2 2 2 1 LysR substrate binding domain LytR_cpsA_psr PF03816.14 KIR63057.1 - 6.9e-34 117.2 0.0 9e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain UNC119_bdg PF15435.6 KIR63057.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue GMC_oxred_N PF00732.19 KIR63058.1 - 1.8e-14 53.8 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIR63058.1 - 2.4e-14 54.1 0.7 5.7e-14 52.9 0.7 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KIR63058.1 - 2.9e-11 43.5 5.1 1.1e-10 41.7 5.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR63058.1 - 3.5e-07 29.7 0.0 0.00018 20.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR63058.1 - 5.8e-07 28.9 5.3 9.2e-05 21.7 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIR63058.1 - 3.7e-05 23.9 0.8 0.00019 21.6 0.8 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIR63058.1 - 0.0032 16.2 0.1 0.24 10.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KIR63058.1 - 0.011 16.2 0.1 0.86 10.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 KIR63058.1 - 0.012 15.7 0.2 0.023 14.9 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 KIR63058.1 - 0.013 14.8 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Fer4_7 PF12838.7 KIR63058.1 - 0.03 14.9 0.7 0.058 14.0 0.7 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain OpcA_G6PD_assem PF10128.9 KIR63058.1 - 0.085 12.3 0.6 3 7.3 0.1 2.2 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase subunit GIDA PF01134.22 KIR63058.1 - 0.22 10.6 0.0 0.47 9.5 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Fer4 PF00037.27 KIR63058.1 - 0.24 11.3 3.0 0.4 10.6 3.0 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 KIR63058.1 - 0.24 12.4 6.9 0.41 11.7 6.9 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_4 PF12800.7 KIR63058.1 - 0.56 10.8 3.8 0.94 10.2 3.8 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain GATase PF00117.28 KIR63059.1 - 2.1e-38 132.0 0.0 3e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KIR63059.1 - 3.4e-37 126.4 0.0 7.1e-37 125.4 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.13 KIR63059.1 - 8.8e-10 38.7 0.0 3.1e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 KIR63059.1 - 2.9e-09 36.4 0.2 2.8e-06 26.6 0.1 2.2 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.16 KIR63059.1 - 5e-05 22.3 0.2 9.6e-05 21.3 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KIR63059.1 - 0.00083 18.9 0.0 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KIR63059.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KIR63059.1 - 0.0047 16.7 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KIR63059.1 - 0.011 15.4 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 KIR63059.1 - 0.055 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PspC PF04024.12 KIR63060.1 - 1.7e-19 69.4 0.1 2e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 PspC domain NUDIX PF00293.28 KIR63061.1 - 7.9e-36 123.0 0.2 4.8e-18 65.5 0.1 2.1 2 0 0 2 2 2 2 NUDIX domain NUDIX_4 PF14815.6 KIR63061.1 - 4.3e-07 29.9 0.0 0.011 15.7 0.0 3.3 2 2 0 2 2 2 2 NUDIX domain CDP-OH_P_transf PF01066.21 KIR63062.1 - 4.4e-12 46.6 3.5 4.4e-12 46.6 3.5 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PS_Dcarbxylase PF02666.15 KIR63063.1 - 5.4e-23 81.6 0.2 5.3e-22 78.4 0.2 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase TAT_ubiq PF07706.12 KIR63063.1 - 0.16 12.2 0.2 0.38 11.0 0.2 1.6 1 0 0 1 1 1 0 Aminotransferase ubiquitination site PspC PF04024.12 KIR63064.1 - 1.4e-12 47.2 2.8 1.4e-12 47.2 2.8 2.0 2 0 0 2 2 2 1 PspC domain DUF2154 PF09922.9 KIR63064.1 - 2.6e-10 40.2 0.0 4.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF Pex14_N PF04695.13 KIR63064.1 - 1.7e-06 28.8 0.0 0.11 13.2 0.0 3.1 2 2 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region PspC PF04024.12 KIR63065.1 - 3e-15 55.7 1.9 7.8e-15 54.4 1.9 1.8 1 0 0 1 1 1 1 PspC domain HATPase_c_2 PF13581.6 KIR63065.1 - 1.5e-06 28.2 1.8 1.5e-06 28.1 0.4 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR63065.1 - 1.7e-06 28.5 0.0 4.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIR63066.1 - 7.6e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR63066.1 - 1.9e-20 72.1 0.3 3.4e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR63066.1 - 4.4e-08 32.7 0.6 8.2e-08 31.8 0.6 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR63066.1 - 3.8e-06 26.3 0.9 7.4e-06 25.4 0.9 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Trp_repressor PF01371.19 KIR63066.1 - 0.0015 18.6 0.2 0.0029 17.7 0.2 1.4 1 0 0 1 1 1 1 Trp repressor protein HTH_10 PF04967.12 KIR63066.1 - 0.0021 17.8 0.5 0.037 13.8 0.5 2.4 1 1 0 1 1 1 1 HTH DNA binding domain HTH_38 PF13936.6 KIR63066.1 - 0.0041 16.8 1.3 0.014 15.2 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 KIR63066.1 - 0.0046 17.4 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 KIR63066.1 - 0.005 16.9 0.0 0.021 14.9 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 KIR63066.1 - 0.0066 16.2 0.1 0.023 14.5 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KIR63066.1 - 0.012 15.2 0.1 0.029 13.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KIR63066.1 - 0.022 14.9 0.4 0.089 12.9 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Glycos_transf_1 PF00534.20 KIR63066.1 - 0.026 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2089 PF09862.9 KIR63066.1 - 0.041 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) TadZ_N PF16968.5 KIR63066.1 - 0.06 13.1 0.5 0.1 12.3 0.5 1.4 1 1 0 1 1 1 0 Pilus assembly protein TadZ N-terminal SBP_bac_5 PF00496.22 KIR63067.1 - 1.4e-61 208.6 10.1 1.6e-61 208.3 10.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KIR63068.1 - 4.3e-32 111.4 13.9 4.3e-32 111.4 13.9 1.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Gp_dh_N PF00044.24 KIR63068.1 - 0.028 14.7 0.1 0.047 14.0 0.1 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain BPD_transp_1 PF00528.22 KIR63069.1 - 2.1e-28 99.3 13.1 2.1e-28 99.3 13.1 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KIR63069.1 - 1.8e-07 31.0 0.2 1.8e-07 31.0 0.2 2.6 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_2 PF12679.7 KIR63069.1 - 0.33 10.2 0.1 0.33 10.2 0.1 2.5 1 1 0 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 KIR63070.1 - 2.1e-25 89.8 0.0 2.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR63070.1 - 1.1e-20 73.9 0.1 2.4e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR63070.1 - 4.5e-05 23.4 0.2 0.00032 20.6 0.0 1.9 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR63070.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR63070.1 - 0.0032 17.7 0.2 0.25 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR63070.1 - 0.01 16.3 0.2 0.015 15.7 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KIR63070.1 - 0.041 14.0 0.3 0.073 13.1 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KIR63070.1 - 0.043 13.6 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KIR63070.1 - 0.11 12.1 0.2 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KIR63070.1 - 0.15 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KIR63070.1 - 0.19 10.9 0.0 6.5 5.9 0.2 2.1 2 0 0 2 2 2 0 NB-ARC domain Herpes_ori_bp PF02399.15 KIR63070.1 - 0.28 9.2 0.2 0.37 8.8 0.2 1.1 1 0 0 1 1 1 0 Origin of replication binding protein ABC_tran PF00005.27 KIR63071.1 - 1.5e-34 119.4 0.0 2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR63071.1 - 3.7e-18 65.8 0.1 2.7e-17 63.0 0.1 2.3 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 KIR63071.1 - 0.00034 20.9 0.2 0.0047 17.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR63071.1 - 0.00062 20.2 0.0 0.00085 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIR63071.1 - 0.0013 18.6 0.1 0.16 11.8 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIR63071.1 - 0.0083 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 KIR63071.1 - 0.0085 14.8 0.1 0.48 9.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIR63071.1 - 0.011 15.2 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR63071.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 KIR63071.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KIR63071.1 - 0.033 14.6 0.0 0.13 12.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KIR63071.1 - 0.051 13.7 0.5 0.1 12.7 0.5 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KIR63071.1 - 0.059 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KIR63071.1 - 0.072 12.8 0.2 0.86 9.3 0.1 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KIR63071.1 - 0.085 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 KIR63071.1 - 0.086 12.7 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 KIR63071.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIR63071.1 - 0.13 11.6 0.0 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 KIR63071.1 - 0.14 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KIR63071.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 KIR63071.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KIR63071.1 - 0.21 10.8 0.1 0.33 10.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain 5_nucleotid_C PF02872.18 KIR63072.1 - 2e-41 141.9 0.3 3.7e-41 141.0 0.3 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIR63072.1 - 0.00036 21.1 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UvrD-helicase PF00580.21 KIR63073.1 - 6.6e-77 259.1 0.0 2e-76 257.6 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KIR63073.1 - 9.4e-66 222.6 0.0 4.5e-33 115.1 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIR63073.1 - 3.7e-35 121.4 0.0 1.2e-34 119.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KIR63073.1 - 4e-11 42.6 0.3 2.1e-10 40.3 0.3 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KIR63073.1 - 1.3e-08 34.8 0.9 0.00021 21.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KIR63073.1 - 0.011 15.4 0.2 1.4 8.6 0.0 3.2 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Exonuc_V_gamma PF04257.14 KIR63073.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit TPR_2 PF07719.17 KIR63074.1 - 2.1e-07 30.5 2.9 8.2e-06 25.6 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIR63074.1 - 2.3e-07 30.3 1.7 0.0001 22.1 0.5 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIR63074.1 - 9.3e-07 29.1 6.5 2.1e-05 24.7 0.2 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIR63074.1 - 1.4e-06 28.5 0.3 0.00063 20.2 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIR63074.1 - 2.9e-06 26.9 0.1 2.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIR63074.1 - 3e-06 27.0 0.0 0.00033 20.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIR63074.1 - 5.6e-06 26.5 17.2 0.00014 22.2 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIR63074.1 - 6.1e-06 26.6 1.0 0.0019 18.7 0.6 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIR63074.1 - 0.00014 21.6 5.6 0.13 12.2 0.4 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIR63074.1 - 0.0068 17.0 7.0 0.043 14.5 2.7 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIR63074.1 - 0.0083 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIR63074.1 - 0.0084 16.9 0.2 0.0084 16.9 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Haem_oxygenas_2 PF14518.6 KIR63074.1 - 0.046 13.5 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Iron-containing redox enzyme TPR_11 PF13414.6 KIR63074.1 - 0.091 12.5 0.1 2.3 8.0 0.0 2.7 2 1 1 3 3 3 0 TPR repeat SusD_RagB PF07980.11 KIR63074.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 SusD family Peptidase_M23 PF01551.22 KIR63075.1 - 5.6e-32 109.8 3.4 8.1e-32 109.3 3.4 1.2 1 0 0 1 1 1 1 Peptidase family M23 RnfC_N PF13375.6 KIR63075.1 - 0.0059 16.5 0.3 0.36 10.8 0.1 2.3 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 KIR63075.1 - 0.08 12.8 1.2 2.9 7.8 0.3 2.8 3 0 0 3 3 3 0 Biotin-lipoyl like SR-25 PF10500.9 KIR63075.1 - 0.12 11.9 3.1 0.17 11.5 3.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M23 PF01551.22 KIR63076.1 - 2.3e-31 107.8 2.3 4.5e-31 106.9 2.3 1.5 1 0 0 1 1 1 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 KIR63076.1 - 0.0022 17.8 0.3 0.0052 16.6 0.3 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like B12-binding PF02310.19 KIR63077.1 - 5.6e-24 84.5 0.9 6.4e-24 84.3 0.9 1.1 1 0 0 1 1 1 1 B12 binding domain QRPTase_C PF01729.19 KIR63077.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ATP-grasp_2 PF08442.10 KIR63078.1 - 2.5e-67 226.4 0.7 3.7e-67 225.8 0.7 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KIR63078.1 - 6.4e-13 48.8 1.8 1.8e-12 47.4 0.3 2.3 2 1 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 KIR63078.1 - 1.3e-09 37.8 1.6 2.5e-09 36.9 1.6 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KIR63078.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KIR63078.1 - 0.008 15.7 1.3 0.016 14.7 1.3 1.6 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CoA_binding PF02629.19 KIR63079.1 - 7.6e-26 90.6 3.7 1.3e-25 89.9 2.1 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KIR63079.1 - 6.3e-15 55.3 0.5 1.4e-14 54.2 0.5 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KIR63079.1 - 6.8e-11 42.1 0.1 1.2e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIR63079.1 - 2.7e-06 27.9 0.0 1.2e-05 25.7 0.0 2.0 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KIR63079.1 - 0.0086 16.9 0.2 0.05 14.4 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KIR63079.1 - 0.057 14.0 0.8 0.12 13.0 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIR63079.1 - 0.072 12.5 0.3 3.1 7.2 0.1 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4190 PF13828.6 KIR63080.1 - 0.00083 19.1 7.1 0.0035 17.1 7.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) DUF456 PF04306.13 KIR63080.1 - 0.042 14.1 2.7 0.042 14.1 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF4234 PF14018.6 KIR63080.1 - 0.05 13.7 0.7 0.061 13.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF2207 PF09972.9 KIR63080.1 - 0.28 9.9 1.0 0.32 9.7 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5362 PF17319.2 KIR63080.1 - 0.68 9.8 12.5 0.13 12.2 5.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5362) DUF4064 PF13273.6 KIR63080.1 - 2.4 8.5 8.3 7.1 7.0 8.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4190 PF13828.6 KIR63082.1 - 3.9e-09 36.1 10.0 3.9e-09 36.1 10.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) Tetraspanin PF00335.20 KIR63082.1 - 0.87 9.2 4.3 1.3 8.7 4.3 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 KIR63082.1 - 3.8 8.0 5.5 25 5.4 5.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) CD225 PF04505.12 KIR63083.1 - 1e-18 67.2 2.8 1e-18 67.2 2.8 2.0 1 1 1 2 2 2 2 Interferon-induced transmembrane protein Peptidase_M56 PF05569.11 KIR63083.1 - 0.045 12.9 0.5 0.053 12.7 0.5 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4190 PF13828.6 KIR63083.1 - 0.17 11.7 9.4 4 7.3 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) TMIE PF16038.5 KIR63083.1 - 0.27 11.1 1.8 0.48 10.3 1.8 1.4 1 0 0 1 1 1 0 TMIE protein Formyl_trans_N PF00551.19 KIR63084.1 - 1.4e-46 158.5 0.0 1.6e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase AICARFT_IMPCHas PF01808.18 KIR63085.1 - 2.6e-114 381.6 0.6 3.2e-114 381.3 0.6 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KIR63085.1 - 5.2e-24 84.3 0.1 1.7e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain THF_DHG_CYH_C PF02882.19 KIR63086.1 - 2e-58 196.2 1.5 2.7e-58 195.8 1.5 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KIR63086.1 - 2.7e-35 121.2 0.0 3.5e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ldh_1_N PF00056.23 KIR63087.1 - 3.3e-36 124.5 0.3 5e-36 123.9 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KIR63087.1 - 2.1e-21 76.6 0.1 3.1e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIR63087.1 - 0.00013 21.6 2.2 0.0002 21.0 1.1 1.9 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KIR63087.1 - 0.0063 16.7 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glyco_hydro_4 PF02056.16 KIR63087.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase T2SSE_N PF05157.15 KIR63087.1 - 0.036 14.3 0.0 2.9 8.2 0.1 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain DAO PF01266.24 KIR63087.1 - 0.04 13.5 4.3 0.37 10.3 0.1 3.2 1 1 3 4 4 4 0 FAD dependent oxidoreductase LRR_9 PF14580.6 KIR63087.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat F420_oxidored PF03807.17 KIR63087.1 - 1.9 9.1 4.6 2.9 8.5 0.1 3.0 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Lactamase_B PF00753.27 KIR63088.1 - 1.4e-22 80.7 5.0 2.1e-22 80.1 5.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR63088.1 - 0.00052 19.6 0.3 0.00083 18.9 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Iso_dh PF00180.20 KIR63089.1 - 1.2e-68 231.9 0.0 1.3e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 KIR63089.1 - 0.018 15.8 0.1 0.51 11.1 0.0 2.3 2 0 0 2 2 2 0 Phenylalanine zipper GalP_UDP_transf PF01087.22 KIR63090.1 - 5.9e-37 127.9 0.0 9.5e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KIR63090.1 - 3.9e-16 59.2 0.0 7.5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DeoRC PF00455.22 KIR63091.1 - 1.2e-49 168.3 0.1 1.6e-49 167.9 0.1 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 KIR63091.1 - 7.1e-20 70.5 0.4 1.4e-19 69.6 0.4 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KIR63091.1 - 9.3e-09 35.1 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 KIR63091.1 - 2.3e-06 27.1 0.3 5.9e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 KIR63091.1 - 0.00067 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KIR63091.1 - 0.00079 19.2 0.4 0.00079 19.2 0.4 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR63091.1 - 0.00095 19.0 2.4 0.0026 17.6 0.2 2.6 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 KIR63091.1 - 0.0026 17.5 1.8 0.0032 17.2 0.2 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KIR63091.1 - 0.0058 16.1 1.7 0.35 10.4 0.3 2.9 2 1 0 2 2 2 1 Sigma-70, region 4 HTH_20 PF12840.7 KIR63091.1 - 0.0062 16.6 5.5 0.036 14.1 0.3 3.3 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_5 PF01022.20 KIR63091.1 - 0.0077 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 KIR63091.1 - 0.0079 15.7 0.1 0.079 12.5 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding FaeA PF04703.12 KIR63091.1 - 0.014 15.8 0.1 0.037 14.4 0.0 1.8 2 0 0 2 2 2 0 FaeA-like protein HTH_28 PF13518.6 KIR63091.1 - 0.021 14.9 0.1 0.021 14.9 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain RPA_C PF08784.11 KIR63091.1 - 0.037 14.7 0.0 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 Replication protein A C terminal Sigma70_ECF PF07638.11 KIR63091.1 - 0.049 13.5 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 ECF sigma factor Rrf2 PF02082.20 KIR63091.1 - 0.066 13.6 0.1 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator Put_DNA-bind_N PF06971.13 KIR63091.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus APS_kinase PF01583.20 KIR63092.1 - 7.2e-55 185.2 0.0 1.6e-54 184.1 0.0 1.6 2 0 0 2 2 2 1 Adenylylsulphate kinase PUA_2 PF14306.6 KIR63092.1 - 9.5e-18 64.4 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain ATP-sulfurylase PF01747.17 KIR63092.1 - 3.6e-16 59.3 0.0 8.4e-13 48.3 0.0 2.3 1 1 0 1 1 1 1 ATP-sulfurylase AAA_33 PF13671.6 KIR63092.1 - 1.3e-08 35.1 0.0 3.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIR63092.1 - 3.3e-05 23.5 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.23 KIR63092.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KIR63092.1 - 0.00043 19.3 0.0 0.00084 18.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KIR63092.1 - 0.00071 18.9 0.1 0.0018 17.6 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KIR63092.1 - 0.00074 19.9 0.1 0.0018 18.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 KIR63092.1 - 0.0021 17.9 1.8 0.15 11.9 0.1 2.5 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KIR63092.1 - 0.0055 16.4 1.1 0.03 14.1 1.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR63092.1 - 0.0066 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KIR63092.1 - 0.015 15.9 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KIR63092.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 KIR63092.1 - 0.035 14.0 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KIR63092.1 - 0.04 13.9 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KIR63092.1 - 0.047 13.4 0.6 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase ParA PF10609.9 KIR63092.1 - 0.051 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_17 PF13207.6 KIR63092.1 - 0.072 13.5 0.0 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIR63092.1 - 0.074 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIR63092.1 - 0.075 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KIR63092.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KIR63092.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 NTPase SRP54 PF00448.22 KIR63092.1 - 0.19 11.4 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CoaE PF01121.20 KIR63092.1 - 0.21 11.2 0.1 0.38 10.4 0.1 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase PIF1 PF05970.14 KIR63092.1 - 0.21 10.7 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase DM13 PF10517.9 KIR63093.1 - 6.7e-29 100.5 0.0 8.9e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 Ribosomal_60s PF00428.19 KIR63093.1 - 4.9 7.8 8.7 1.8 9.2 3.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein VTC PF09359.10 KIR63094.1 - 1.5e-32 113.1 0.1 3e-32 112.1 0.1 1.4 1 1 0 1 1 1 1 VTC domain DUF4956 PF16316.5 KIR63095.1 - 1.4e-17 63.9 10.1 2.3e-17 63.2 10.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4956) MgtC PF02308.16 KIR63095.1 - 0.0006 20.2 12.5 0.001 19.4 12.5 1.3 1 0 0 1 1 1 1 MgtC family DUF4271 PF14093.6 KIR63095.1 - 0.01 15.7 3.5 0.01 15.7 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF3810 PF12725.7 KIR63095.1 - 0.12 11.7 8.8 0.12 11.7 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) CotH PF08757.11 KIR63096.1 - 4e-33 115.3 0.0 7.3e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 CotH kinase protein YfhD PF14151.6 KIR63096.1 - 0.022 14.9 0.9 0.056 13.6 0.9 1.7 1 0 0 1 1 1 0 YfhD-like protein DUF4574 PF15141.6 KIR63097.1 - 0.15 12.0 3.5 0.22 11.5 0.7 2.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 MerC PF03203.14 KIR63097.1 - 1.2 9.6 21.4 1.5 9.3 2.3 3.1 1 1 2 3 3 3 0 MerC mercury resistance protein TauE PF01925.19 KIR63097.1 - 2 8.0 32.5 1.2e+02 2.1 32.3 2.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE tRNA-synt_1 PF00133.22 KIR63098.1 - 4.5e-83 279.5 0.0 6e-62 209.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIR63098.1 - 2.3e-24 86.1 0.0 3.3e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIR63098.1 - 1.1e-14 54.0 0.0 2.4e-07 29.8 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KIR63098.1 - 7.2e-06 25.2 0.0 0.00049 19.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 KIR63098.1 - 0.0001 21.8 0.0 0.066 12.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ABC_membrane PF00664.23 KIR63099.1 - 2.2e-43 148.9 0.1 2.8e-43 148.6 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR63099.1 - 1.2e-30 106.8 0.0 1.9e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR63099.1 - 0.00091 19.6 3.5 0.0013 19.2 2.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR63099.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KIR63099.1 - 0.022 14.5 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KIR63099.1 - 0.023 14.5 0.2 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane_3 PF13748.6 KIR63099.1 - 0.038 13.2 0.8 0.091 12.0 0.8 1.6 1 1 0 1 1 1 0 ABC transporter transmembrane region SMC_N PF02463.19 KIR63099.1 - 0.072 12.5 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR63099.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIR63099.1 - 0.12 12.2 0.1 21 5.0 0.0 2.3 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 KIR63099.1 - 0.14 12.0 0.4 4.7 7.1 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AlkA_N PF06029.11 KIR63100.1 - 7.7e-35 119.7 1.4 1.4e-34 118.8 0.5 1.9 2 0 0 2 2 2 1 AlkA N-terminal domain Ada_Zn_binding PF02805.16 KIR63100.1 - 8.2e-29 99.4 7.8 1.6e-28 98.5 7.8 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 KIR63100.1 - 3.3e-17 62.5 1.3 8.2e-17 61.3 1.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR63100.1 - 7.5e-05 22.7 0.0 0.07 13.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HhH-GPD PF00730.25 KIR63100.1 - 0.0026 18.2 0.0 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EamA PF00892.20 KIR63101.1 - 5.5e-30 104.3 24.5 6.6e-16 58.7 11.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 KIR63101.1 - 9.5 5.2 11.0 0.99 8.4 4.8 1.9 2 0 0 2 2 2 0 Magnesium transporter NIPA Peptidase_S51 PF03575.17 KIR63102.1 - 3e-24 85.8 0.0 4.1e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 YchF-GTPase_C PF06071.13 KIR63103.1 - 3.2e-39 133.0 0.0 6.4e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KIR63103.1 - 4.7e-22 78.2 0.0 3.7e-21 75.3 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIR63103.1 - 1.9e-08 34.0 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KIR63103.1 - 0.00021 21.3 0.3 0.00098 19.1 0.3 2.1 1 1 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 KIR63103.1 - 0.0051 16.9 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 KIR63103.1 - 0.079 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KIR63103.1 - 0.08 13.5 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIR63103.1 - 0.15 12.3 0.2 11 6.3 0.0 2.5 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 KIR63103.1 - 0.18 11.3 0.1 0.59 9.5 0.0 1.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit RibD_C PF01872.17 KIR63104.1 - 2.6e-21 76.4 0.0 6.2e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 RibD C-terminal domain His_Phos_1 PF00300.22 KIR63105.1 - 1.2e-31 109.9 0.0 1.4e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KIR63105.1 - 0.07 12.5 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Glyoxalase_6 PF18029.1 KIR63106.1 - 0.0002 22.1 0.8 0.00025 21.8 0.8 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KIR63106.1 - 0.0058 16.8 0.1 0.049 13.8 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KIR63106.1 - 0.19 11.7 0.0 0.4 10.6 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Hydrolase_4 PF12146.8 KIR63107.1 - 4.4e-06 26.1 0.3 0.00044 19.6 0.3 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR63107.1 - 2.3e-05 24.2 0.0 0.0023 17.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 KIR63107.1 - 0.0057 16.0 0.2 0.07 12.4 0.3 2.3 2 1 0 2 2 2 1 Secretory lipase DUF218 PF02698.17 KIR63108.1 - 6.9e-23 81.1 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain CcmH PF03918.14 KIR63109.1 - 0.012 14.9 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3180 PF11377.8 KIR63109.1 - 0.035 14.2 1.0 0.042 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF2157 PF09925.9 KIR63109.1 - 0.036 13.9 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) TMEM51 PF15345.6 KIR63109.1 - 0.06 13.2 0.0 0.063 13.1 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 ArsP_1 PF03773.13 KIR63109.1 - 0.064 12.4 0.0 0.064 12.4 0.0 1.0 1 0 0 1 1 1 0 Predicted permease NAD_binding_2 PF03446.15 KIR63110.1 - 3.7e-21 75.9 0.0 7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIR63110.1 - 3e-10 40.6 0.3 1.2e-09 38.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIR63110.1 - 0.00075 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KIR63110.1 - 0.0024 17.8 0.1 0.0049 16.8 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KIR63110.1 - 0.0027 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KIR63110.1 - 0.0045 17.0 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KIR63110.1 - 0.0059 16.0 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MerR_1 PF13411.6 KIR63111.1 - 4.6e-20 71.5 0.0 8.5e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR63111.1 - 1.6e-16 59.7 6.7 2.7e-16 59.0 5.2 2.1 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KIR63111.1 - 3.6e-06 27.4 0.1 5.6e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 MerR, DNA binding AbiEi_4 PF13338.6 KIR63111.1 - 0.012 15.7 0.8 0.03 14.5 0.8 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin MarR_2 PF12802.7 KIR63111.1 - 0.25 11.3 4.7 0.82 9.6 0.1 3.3 3 2 0 3 3 3 0 MarR family bPH_1 PF08000.11 KIR63112.1 - 5.6e-08 32.9 0.0 6.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 KIR63112.1 - 1.5e-07 31.7 0.1 1.7e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain GRAM PF02893.20 KIR63112.1 - 8.2e-05 22.5 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 GRAM domain bPH_2 PF03703.14 KIR63112.1 - 9.3e-05 22.6 0.3 0.001 19.2 0.2 2.1 1 1 1 2 2 2 1 Bacterial PH domain Methyltransf_25 PF13649.6 KIR63113.1 - 1.9e-15 57.3 0.0 3.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR63113.1 - 2.2e-15 57.0 0.0 3.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR63113.1 - 2.7e-12 46.8 0.0 1.1e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR63113.1 - 1.4e-10 41.8 0.0 2.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR63113.1 - 1.2e-08 34.9 0.0 2.3e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 KIR63113.1 - 5.1e-06 26.2 0.0 7.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KIR63113.1 - 6.6e-05 22.4 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 KIR63113.1 - 0.00035 20.2 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIR63113.1 - 0.0051 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KIR63113.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.13 KIR63113.1 - 0.014 14.8 0.3 0.035 13.5 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KIR63113.1 - 0.016 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIR63113.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KIR63113.1 - 0.27 10.7 0.0 1.5 8.3 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Pterin_4a PF01329.19 KIR63114.1 - 7.3e-06 26.1 0.0 8.1e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NUDIX PF00293.28 KIR63115.1 - 2.2e-15 56.8 0.2 2.7e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIR63115.1 - 9.6e-09 35.2 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Fer2_3 PF13085.6 KIR63116.1 - 4.7e-27 94.2 0.0 8.4e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 KIR63116.1 - 1.3e-14 54.4 5.7 1.3e-14 54.4 5.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KIR63116.1 - 4e-05 23.8 3.2 0.12 12.5 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KIR63116.1 - 8.4e-05 23.0 6.1 8.4e-05 23.0 6.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KIR63116.1 - 0.00051 19.9 0.7 0.00051 19.9 0.7 2.0 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KIR63116.1 - 0.032 14.8 5.8 0.032 14.8 5.8 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIR63116.1 - 0.077 13.2 11.3 0.23 11.7 0.4 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer2_4 PF13510.6 KIR63116.1 - 0.087 12.9 0.4 0.087 12.9 0.4 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.6 KIR63116.1 - 4.9 7.3 17.8 0.21 11.7 9.6 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain FAD_binding_2 PF00890.24 KIR63117.1 - 9.4e-93 311.5 1.4 1.2e-92 311.1 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIR63117.1 - 1.6e-23 83.1 0.0 3.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KIR63117.1 - 2e-06 27.3 0.8 1.3e-05 24.6 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR63117.1 - 0.00014 21.3 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KIR63117.1 - 0.00033 20.4 6.3 0.021 14.4 6.3 3.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR63117.1 - 0.00048 19.0 0.5 0.00048 19.0 0.5 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KIR63117.1 - 0.029 13.6 0.6 0.045 13.0 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIR63117.1 - 0.036 13.3 2.6 0.048 12.9 1.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR63117.1 - 0.038 13.1 9.6 0.014 14.5 4.4 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 KIR63117.1 - 0.052 12.8 0.2 0.052 12.8 0.2 2.6 3 0 0 3 3 3 0 Thi4 family AlaDh_PNT_C PF01262.21 KIR63117.1 - 0.13 11.5 0.7 0.22 10.8 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KIR63117.1 - 3.2 8.1 6.3 6.9 7.0 2.1 3.3 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain PmbA_TldD PF01523.16 KIR63119.1 - 1.9e-36 126.4 0.1 2.5e-36 126.0 0.1 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 KIR63120.1 - 1e-48 166.6 0.0 1.3e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Uma2 PF05685.12 KIR63121.1 - 1.2e-23 83.5 0.2 1.4e-23 83.3 0.2 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease ABC_tran PF00005.27 KIR63122.1 - 2.9e-25 89.4 0.0 3.8e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR63122.1 - 2.1e-18 66.6 0.2 5.3e-18 65.3 0.0 1.8 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR63122.1 - 2.3e-08 34.2 0.3 1.3e-06 28.5 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR63122.1 - 0.0027 17.2 0.1 0.011 15.2 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR63122.1 - 0.016 15.4 0.4 0.077 13.3 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR63122.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIR63123.1 - 4.5e-30 104.9 0.0 6.2e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR63123.1 - 2.2e-17 63.3 0.1 3.8e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 KIR63123.1 - 2.6e-05 24.5 0.0 0.00022 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIR63123.1 - 0.0032 17.3 0.1 0.052 13.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR63123.1 - 0.033 14.6 0.2 0.059 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KIR63123.1 - 0.046 13.2 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain TniB PF05621.11 KIR63123.1 - 0.079 12.4 0.0 0.77 9.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein BPD_transp_1 PF00528.22 KIR63124.1 - 1.1e-24 87.2 10.0 1.1e-24 87.2 10.0 2.4 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KIR63124.1 - 2.2e-09 37.2 0.2 2.2e-09 37.2 0.2 3.3 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C EMP70 PF02990.16 KIR63124.1 - 0.036 12.8 1.8 0.069 11.8 1.8 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 BPD_transp_1 PF00528.22 KIR63125.1 - 6.1e-38 130.4 11.2 6.1e-38 130.4 11.2 1.8 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component RTA1 PF04479.13 KIR63125.1 - 0.28 10.8 4.5 0.06 12.9 0.6 1.8 2 0 0 2 2 2 0 RTA1 like protein SBP_bac_5 PF00496.22 KIR63126.1 - 6.5e-52 176.8 5.4 1e-51 176.1 5.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle PmrD PF11183.8 KIR63126.1 - 0.062 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Peptidase_S9 PF00326.21 KIR63128.1 - 4.1e-42 144.1 0.0 6.1e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 KIR63128.1 - 1.3e-28 99.8 0.0 1.3e-27 96.5 0.0 2.0 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 KIR63128.1 - 8.2e-08 32.2 0.4 2.4e-06 27.4 0.2 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIR63128.1 - 2.6e-05 23.6 0.1 0.0001 21.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KIR63128.1 - 0.017 14.7 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 KIR63128.1 - 0.037 12.7 0.0 1.2 7.7 0.0 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KIR63128.1 - 0.055 13.1 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold PIG-L PF02585.17 KIR63129.1 - 7.9e-26 91.2 0.8 1.2e-25 90.7 0.8 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Acyl_transf_3 PF01757.22 KIR63130.1 - 0.059 12.4 4.6 0.069 12.2 4.6 1.0 1 0 0 1 1 1 0 Acyltransferase family DUF4203 PF13886.6 KIR63130.1 - 0.61 9.7 14.4 0.1 12.3 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) YtxH PF12732.7 KIR63130.1 - 3.6 8.2 5.0 3.9 8.1 0.1 2.6 2 0 0 2 2 2 0 YtxH-like protein FR47 PF08445.10 KIR63131.1 - 5.5e-09 35.9 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KIR63131.1 - 1.6e-08 34.8 0.1 2.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR63131.1 - 0.00012 22.4 0.0 0.00025 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR63131.1 - 0.00031 21.4 0.0 0.00057 20.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR63131.1 - 0.0067 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4 PF00037.27 KIR63132.1 - 3.5e-10 39.3 17.9 1.4e-08 34.2 5.2 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KIR63132.1 - 5.4e-07 30.5 1.8 0.0003 21.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KIR63132.1 - 1.5e-05 25.5 12.6 0.00026 21.5 13.1 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR63132.1 - 0.00015 21.7 4.9 0.00015 21.7 4.9 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KIR63132.1 - 0.00017 21.7 9.3 0.00033 20.7 9.3 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR63132.1 - 0.00019 21.5 9.0 0.0002 21.4 0.8 2.1 1 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KIR63132.1 - 0.00026 21.2 2.0 0.00026 21.2 2.0 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 KIR63132.1 - 0.00062 20.2 4.4 0.002 18.5 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIR63132.1 - 0.0014 18.6 3.7 0.0014 18.6 3.7 2.7 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 KIR63132.1 - 0.0015 18.7 14.8 0.0065 16.6 14.8 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KIR63132.1 - 0.015 15.8 13.0 0.057 14.0 2.5 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIR63132.1 - 0.088 13.4 9.8 0.13 12.8 1.9 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_11 PF13247.6 KIR63132.1 - 0.14 12.3 5.5 0.22 11.7 5.5 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIR63132.1 - 0.25 12.4 16.6 0.25 12.4 7.1 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain PDH PF02153.17 KIR63133.1 - 1.6e-48 164.9 0.0 2.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KIR63133.1 - 3.5e-05 24.3 0.0 7.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIR63133.1 - 0.00016 21.9 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KIR63133.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KIR63133.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 KIR63133.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIR63133.1 - 0.26 10.8 0.0 0.5 9.9 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SIMPL PF04402.14 KIR63134.1 - 1.4e-29 104.0 0.0 1.6e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) AAA_33 PF13671.6 KIR63135.1 - 8.7e-06 25.9 0.2 0.00026 21.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KIR63135.1 - 1.7e-05 24.0 0.1 2.5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KIR63135.1 - 2.9e-05 24.6 0.1 0.00028 21.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIR63135.1 - 0.0025 18.3 0.1 0.024 15.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KIR63135.1 - 0.0028 17.4 0.0 0.0069 16.1 0.0 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KIR63135.1 - 0.0031 16.8 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 KIR63135.1 - 0.008 15.6 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KIR63135.1 - 0.0085 16.5 0.2 0.013 15.8 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIR63135.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIR63135.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIR63135.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIR63135.1 - 0.03 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KIR63135.1 - 0.032 14.7 0.0 0.048 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KIR63135.1 - 0.062 13.4 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KIR63135.1 - 0.093 13.0 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR63135.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TPR_21 PF09976.9 KIR63136.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain PAP2 PF01569.21 KIR63136.1 - 0.78 9.5 0.0 0.78 9.5 0.0 3.4 4 0 0 4 4 4 0 PAP2 superfamily Mac PF12464.8 KIR63137.1 - 6.1e-13 48.8 0.4 1e-12 48.1 0.4 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KIR63137.1 - 9.7e-13 47.3 7.2 9e-09 34.7 4.9 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIR63137.1 - 3.6e-09 36.2 7.0 1.6e-06 27.7 5.3 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase THDPS_M PF14789.6 KIR63138.1 - 4.9e-16 58.5 0.1 1.1e-15 57.4 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase middle Hexapep_2 PF14602.6 KIR63138.1 - 1.1e-14 53.9 13.5 1.2e-14 53.8 2.9 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KIR63138.1 - 1.7e-05 24.3 11.0 0.00023 20.7 1.0 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) THDPS_N PF14790.6 KIR63138.1 - 0.0084 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Peptidase_M20 PF01546.28 KIR63139.1 - 1.7e-21 76.9 0.0 3.3e-21 76.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIR63139.1 - 2.4e-14 53.1 0.0 6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIR63139.1 - 8.5e-07 28.9 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 Lysine_decarbox PF03641.14 KIR63140.1 - 2.6e-34 118.2 0.0 3.1e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KIR63140.1 - 1.8e-20 73.1 0.1 2.1e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 KIR63140.1 - 0.00036 19.8 0.3 0.0005 19.4 0.3 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A CSD PF00313.22 KIR63141.1 - 1.8e-31 107.8 0.1 1.9e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KIR63141.1 - 0.0023 17.6 0.5 0.0032 17.1 0.2 1.5 2 0 0 2 2 2 1 Ribonuclease B OB domain DEAD PF00270.29 KIR63142.1 - 5.3e-43 146.8 0.0 8.6e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR63142.1 - 1e-25 90.2 0.0 3.3e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR63142.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit XdhC_C PF13478.6 KIR63142.1 - 0.016 15.7 2.2 0.057 13.9 0.2 2.5 3 0 0 3 3 3 0 XdhC Rossmann domain BPD_transp_1 PF00528.22 KIR63144.1 - 1.5e-13 50.9 14.8 1.5e-13 50.9 14.8 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KIR63145.1 - 2e-26 93.1 0.0 5.1e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR63145.1 - 4.1e-05 23.5 0.6 0.074 12.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR63145.1 - 0.00027 20.4 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIR63145.1 - 0.00041 20.3 0.1 0.00068 19.6 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIR63145.1 - 0.002 18.6 0.7 0.0051 17.2 0.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIR63145.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR63145.1 - 0.0076 16.5 0.9 0.038 14.3 0.9 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 KIR63145.1 - 0.013 14.3 0.0 0.092 11.5 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 KIR63145.1 - 0.014 15.0 1.3 0.046 13.3 1.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR63145.1 - 0.02 14.6 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIR63145.1 - 0.028 14.5 0.3 0.068 13.3 0.1 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KIR63145.1 - 0.032 14.5 2.2 0.062 13.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KIR63145.1 - 0.036 14.5 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIR63145.1 - 0.044 13.8 0.2 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIR63145.1 - 0.069 13.1 1.4 0.17 11.8 0.1 2.1 2 1 0 2 2 2 0 NACHT domain Rad17 PF03215.15 KIR63145.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KIR63145.1 - 0.11 13.1 0.1 0.65 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KIR63145.1 - 0.2 11.1 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_23 PF13476.6 KIR63145.1 - 0.22 12.0 0.0 0.33 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIR63145.1 - 0.28 11.6 0.1 0.47 10.9 0.1 1.3 1 0 0 1 1 1 0 RNA helicase NMT1_2 PF13379.6 KIR63146.1 - 4.7e-38 131.3 0.1 6.7e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KIR63146.1 - 5.4e-13 49.4 0.2 7.2e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KIR63146.1 - 2.2e-10 40.6 0.2 1.8e-09 37.6 0.2 2.0 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KIR63146.1 - 2.4e-06 27.1 0.0 0.00089 18.7 0.0 2.4 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Peptidase_M16_C PF05193.21 KIR63147.1 - 4.8e-25 88.6 0.0 7.2e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIR63147.1 - 7.6e-19 68.2 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIR63148.1 - 2e-21 76.8 0.0 7e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIR63148.1 - 1.6e-07 31.4 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) acVLRF1 PF18859.1 KIR63148.1 - 0.31 11.3 7.1 1.6 9.1 2.0 2.7 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor DUF397 PF04149.12 KIR63150.1 - 3.2e-19 68.7 0.1 3.8e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) FixS PF03597.15 KIR63150.1 - 0.03 14.0 0.3 0.053 13.2 0.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type HTH_31 PF13560.6 KIR63151.1 - 3.7e-18 65.6 4.1 3.7e-18 65.6 4.1 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR63151.1 - 4.3e-07 29.9 0.0 1.1e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR63151.1 - 1.9e-05 24.6 0.0 6.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_18 PF12833.7 KIR63151.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 KIR63152.1 - 2.2e-23 82.7 57.6 9.5e-16 57.7 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIR63152.1 - 7.6e-09 34.6 23.2 2e-05 23.4 3.8 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 KIR63152.1 - 4.4e-05 22.1 34.1 5.8e-05 21.7 34.1 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 KIR63152.1 - 0.00054 18.9 14.6 0.022 13.6 3.4 2.3 2 0 0 2 2 2 2 MFS_1 like family Glutaredoxin PF00462.24 KIR63153.1 - 1.2e-14 54.2 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KIR63153.1 - 2.7e-05 24.5 0.0 3e-05 24.4 0.0 1.2 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 KIR63153.1 - 2.7e-05 24.5 0.0 3.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 KIR63153.1 - 0.00046 20.6 0.1 0.003 18.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 KIR63153.1 - 0.0014 18.5 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin GST_N_2 PF13409.6 KIR63153.1 - 0.014 15.7 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UvrD-helicase PF00580.21 KIR63154.1 - 9.7e-43 146.9 0.0 4.2e-22 79.1 0.0 2.2 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KIR63154.1 - 1.2e-41 143.2 0.0 1.2e-23 84.1 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIR63154.1 - 1.3e-34 119.6 0.1 2.8e-34 118.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain HRDC PF00570.23 KIR63154.1 - 6.8e-19 67.6 0.1 1.7e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 HRDC domain UvrD_C_2 PF13538.6 KIR63154.1 - 8.9e-13 47.9 0.6 7.7e-12 44.9 0.6 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KIR63154.1 - 0.00025 20.8 12.0 0.003 17.3 9.9 2.8 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIR63154.1 - 0.025 14.3 0.8 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KIR63154.1 - 0.12 12.0 0.0 1.9 8.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain Whib PF02467.16 KIR63156.1 - 1.2e-13 51.4 0.1 1.9e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Transcription factor WhiB AT_hook PF02178.19 KIR63156.1 - 0.0092 15.7 2.7 0.018 14.8 2.7 1.5 1 0 0 1 1 1 1 AT hook motif ABC1 PF03109.16 KIR63158.1 - 8.6e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KIR63158.1 - 9e-05 22.5 15.7 0.0016 18.5 12.4 3.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIR63158.1 - 0.28 10.5 0.0 0.44 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ThiF PF00899.21 KIR63159.1 - 8.8e-09 35.1 0.3 2.8e-07 30.1 0.3 2.3 1 1 0 1 1 1 1 ThiF family DUF45 PF01863.17 KIR63160.1 - 1.1e-21 77.8 0.1 5.9e-21 75.5 0.0 1.8 1 1 0 2 2 2 1 Protein of unknown function DUF45 WLM PF08325.10 KIR63160.1 - 6e-05 23.2 0.0 9.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 KIR63160.1 - 0.00031 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family TPR_4 PF07721.14 KIR63160.1 - 9.6 7.2 8.8 15 6.6 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2064 PF09837.9 KIR63161.1 - 0.042 13.7 0.2 0.062 13.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) PDZ_2 PF13180.6 KIR63162.1 - 1.1e-12 48.1 0.1 5.1e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 KIR63162.1 - 1e-08 34.9 0.1 3e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Lon_C PF05362.13 KIR63162.1 - 5.2e-08 32.7 0.3 1.2e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain PDZ PF00595.24 KIR63162.1 - 3.6e-05 24.0 0.0 0.0001 22.6 0.0 1.7 2 0 0 2 2 2 1 PDZ domain CE2_N PF17996.1 KIR63162.1 - 0.016 15.2 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Tricorn_PDZ PF14685.6 KIR63162.1 - 0.018 15.0 0.3 0.21 11.6 0.0 2.6 3 0 0 3 3 3 0 Tricorn protease PDZ domain ChlI PF13541.6 KIR63162.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase UPF0182 PF03699.13 KIR63163.1 - 1.4e-269 896.4 0.0 1.7e-269 896.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) DUF1772 PF08592.11 KIR63164.1 - 0.013 15.9 0.8 0.015 15.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Oxidored_q3 PF00499.20 KIR63164.1 - 0.093 12.4 1.4 1 9.1 0.3 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Baculo_11_kDa PF06143.11 KIR63164.1 - 0.41 10.3 1.6 0.73 9.5 1.6 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5362 PF17319.2 KIR63164.1 - 1.7 8.5 5.3 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5362) SBP_bac_1 PF01547.25 KIR63165.1 - 2.6e-14 53.9 0.0 4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR63165.1 - 7e-13 49.0 0.0 9.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SAICAR_synt PF01259.18 KIR63166.1 - 9.5e-94 313.7 0.0 1.1e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase FGGY_N PF00370.21 KIR63167.1 - 1.8e-77 260.2 0.0 3e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIR63167.1 - 1.2e-63 214.5 1.8 2.3e-63 213.5 1.7 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KIR63167.1 - 0.0086 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family HATPase_c_2 PF13581.6 KIR63168.1 - 3.6e-19 68.9 0.0 4.8e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR63168.1 - 6.6e-07 29.8 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIR63169.1 - 1e-08 35.6 0.0 1.7e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 KIR63169.1 - 6.1e-05 23.5 3.3 6.1e-05 23.5 3.3 2.7 3 0 0 3 3 3 1 Histidine kinase HATPase_c_2 PF13581.6 KIR63171.1 - 8.4e-08 32.2 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain STAS_2 PF13466.6 KIR63171.1 - 0.00043 20.6 4.0 0.0014 18.9 2.9 2.5 2 1 0 2 2 2 1 STAS domain DUF448 PF04296.13 KIR63171.1 - 0.069 13.0 0.0 0.44 10.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF448) adh_short PF00106.25 KIR63172.1 - 3.9e-49 166.8 0.6 4.9e-49 166.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR63172.1 - 9.1e-37 126.8 0.4 1.3e-36 126.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR63172.1 - 6e-12 45.8 1.2 9.1e-12 45.2 1.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIR63172.1 - 0.012 15.0 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIR63172.1 - 0.055 12.9 0.2 0.076 12.5 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NIR_SIR_ferr PF03460.17 KIR63172.1 - 0.12 12.3 0.0 0.42 10.5 0.0 2.0 1 1 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain DFP PF04127.15 KIR63172.1 - 0.49 10.2 3.5 1.1 9.0 3.5 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glycos_transf_1 PF00534.20 KIR63173.1 - 4.2e-30 104.5 0.0 6.6e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR63173.1 - 2e-26 93.4 13.3 2e-26 93.4 13.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR63173.1 - 1.1e-25 90.6 4.2 2e-25 89.7 2.4 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIR63173.1 - 2.7e-24 86.1 0.6 5.3e-24 85.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR63173.1 - 2.7e-09 37.2 0.0 4.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KIR63173.1 - 2.4e-06 27.8 0.0 5.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 NAD_binding_8 PF13450.6 KIR63173.1 - 0.00082 19.5 0.1 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glyco_transf_5 PF08323.11 KIR63173.1 - 0.0021 17.8 0.1 0.036 13.8 0.0 2.2 2 0 0 2 2 2 1 Starch synthase catalytic domain Inositol_P PF00459.25 KIR63174.1 - 1.2e-47 162.7 0.0 1.5e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family SRAP PF02586.14 KIR63175.1 - 2.3e-58 197.3 0.0 2.6e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Whib PF02467.16 KIR63176.1 - 4.9e-22 78.3 3.1 4.9e-22 78.3 3.1 1.5 2 0 0 2 2 2 1 Transcription factor WhiB Abhydrolase_3 PF07859.13 KIR63177.1 - 0.21 11.4 6.7 0.62 9.9 6.8 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Sigma70_r2 PF04542.14 KIR63178.1 - 2.1e-17 62.6 0.2 4.4e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR63178.1 - 7.6e-16 57.5 0.0 1.7e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR63178.1 - 1.2e-11 44.0 0.0 4.7e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR63178.1 - 0.0016 18.4 0.1 0.0029 17.5 0.1 1.4 1 1 0 1 1 1 1 ECF sigma factor TGFb_propeptide PF00688.18 KIR63178.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 TGF-beta propeptide zf-HC2 PF13490.6 KIR63179.1 - 1.6e-06 28.2 8.7 1.6e-06 28.2 8.7 1.7 2 0 0 2 2 2 1 Putative zinc-finger Biotin_lipoyl PF00364.22 KIR63180.1 - 5.7e-19 67.7 5.4 6.5e-19 67.5 5.4 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIR63180.1 - 1.9e-08 34.0 6.1 5.4e-05 22.9 3.4 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 KIR63180.1 - 1.6e-05 24.2 0.7 0.0022 17.3 0.1 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KIR63180.1 - 0.00018 22.2 3.1 0.0046 17.6 1.2 2.0 2 0 0 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.9 KIR63180.1 - 0.0023 17.9 0.3 0.4 10.6 0.1 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2118) Glyco_trans_1_4 PF13692.6 KIR63180.1 - 0.0027 18.1 0.3 0.0028 18.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIR63180.1 - 0.01 15.4 0.1 0.01 15.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 YqfD PF06898.11 KIR63180.1 - 0.016 14.1 2.6 0.56 9.0 0.5 2.0 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD GCV_H PF01597.19 KIR63180.1 - 0.037 13.9 0.6 0.04 13.8 0.6 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 KIR63180.1 - 0.047 13.9 1.7 3.5 7.9 0.4 2.5 1 1 2 3 3 3 0 Peptidase family M23 PYNP_C PF07831.13 KIR63180.1 - 0.065 12.9 0.6 8.4 6.1 0.2 2.2 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain RnfC_N PF13375.6 KIR63180.1 - 0.094 12.7 2.9 3 7.9 0.2 2.0 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Acetyltransf_1 PF00583.25 KIR63181.1 - 3.1e-13 50.0 0.1 3.7e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR63181.1 - 9.1e-12 45.2 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR63181.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR63181.1 - 2.9e-07 30.4 0.0 5.5e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 KIR63181.1 - 2.1e-06 27.8 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIR63181.1 - 0.00065 19.8 0.0 0.0062 16.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR63181.1 - 0.022 14.5 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR63181.1 - 0.023 14.9 1.8 0.17 12.0 1.5 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2934 PF11154.8 KIR63181.1 - 0.17 11.6 0.9 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) TetR_N PF00440.23 KIR63182.1 - 3.6e-18 65.1 0.3 3.6e-18 65.1 0.3 2.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 KIR63182.1 - 0.0015 18.6 0.2 0.0028 17.8 0.2 1.7 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase UPF0122 PF04297.14 KIR63182.1 - 0.0018 18.5 0.4 0.0042 17.3 0.1 1.7 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_20 PF12840.7 KIR63182.1 - 0.0043 17.1 0.2 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR63182.1 - 0.016 15.0 1.3 0.036 13.9 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.12 KIR63182.1 - 0.02 14.7 0.3 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 HTH DNA binding domain HTH_38 PF13936.6 KIR63182.1 - 0.043 13.6 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 KIR63182.1 - 0.065 13.1 0.5 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_11 PF08279.12 KIR63182.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 KIR63182.1 - 0.092 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABATE PF07336.11 KIR63182.1 - 0.099 13.3 10.5 0.023 15.3 7.5 1.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator HTH_5 PF01022.20 KIR63182.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Hemerythrin PF01814.23 KIR63182.1 - 0.51 11.0 3.4 6.4 7.4 0.3 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain MFS_1 PF07690.16 KIR63183.1 - 2.3e-55 187.9 52.0 2.3e-55 187.9 52.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIR63183.1 - 3.9e-19 68.5 21.4 5.9e-19 67.9 21.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIR63183.1 - 8.7e-10 38.0 15.4 8.7e-10 38.0 15.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KIR63183.1 - 0.00026 19.7 39.0 0.0063 15.1 11.3 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein DUF4407 PF14362.6 KIR63183.1 - 0.18 11.2 4.9 0.96 8.7 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPR_2 PF07719.17 KIR63184.1 - 7.9e-10 38.1 4.3 0.0018 18.2 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIR63184.1 - 2.7e-09 37.4 15.1 3.6e-07 30.6 0.5 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIR63184.1 - 8.1e-09 35.6 40.9 0.0013 19.4 1.2 7.8 6 1 2 8 8 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIR63184.1 - 7.9e-08 31.8 0.0 0.0058 16.4 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIR63184.1 - 3.2e-06 27.7 7.3 3.2e-06 27.7 7.3 6.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIR63184.1 - 2.5e-05 23.8 1.0 0.0028 17.3 0.1 3.3 3 1 1 4 4 4 1 TPR repeat TPR_8 PF13181.6 KIR63184.1 - 0.00017 21.5 0.1 1 9.8 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIR63184.1 - 0.00026 21.1 0.1 1.4 9.5 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIR63184.1 - 0.0015 19.1 0.0 0.017 15.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIR63184.1 - 0.0042 17.3 2.6 0.0042 17.3 2.6 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.7 KIR63184.1 - 0.011 16.0 1.2 0.4 10.9 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_10 PF13374.6 KIR63184.1 - 0.067 13.1 15.2 0.28 11.1 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIR63184.1 - 0.11 12.7 0.0 0.58 10.4 0.0 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KIR63184.1 - 0.11 12.5 0.6 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 KIR63184.1 - 0.14 12.3 7.5 1.1 9.5 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma70_r1_2 PF00140.20 KIR63184.1 - 0.23 11.5 0.9 0.53 10.3 0.9 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 TPR_15 PF13429.6 KIR63184.1 - 0.38 9.9 6.9 0.09 12.0 0.4 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIR63184.1 - 1.7 9.0 9.9 0.5 10.7 0.3 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat SIS PF01380.22 KIR63185.1 - 2.8e-29 101.6 0.1 4.4e-15 55.7 0.3 2.9 2 1 0 2 2 2 2 SIS domain PMT_2 PF13231.6 KIR63186.1 - 1.7e-13 51.1 7.5 1.7e-13 51.1 7.5 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2723 PF11028.8 KIR63186.1 - 0.0033 17.4 1.9 0.0069 16.3 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) DUF4516 PF14990.6 KIR63186.1 - 0.47 10.2 2.2 3.5 7.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) NIR_SIR PF01077.22 KIR63187.1 - 5.6e-47 159.2 0.0 4.7e-35 120.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KIR63187.1 - 6.7e-35 118.8 0.4 4.5e-18 64.9 0.0 2.8 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain PAPS_reduct PF01507.19 KIR63188.1 - 4.2e-45 153.9 0.0 5.5e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DAGK_cat PF00781.24 KIR63189.1 - 6.5e-26 90.4 0.0 9.3e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KIR63189.1 - 6.1e-06 25.6 0.3 1.2e-05 24.7 0.3 1.4 1 1 0 1 1 1 1 ATP-NAD kinase HATPase_c_2 PF13581.6 KIR63191.1 - 3.4e-06 27.0 0.2 3.9e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Acetyltransf_1 PF00583.25 KIR63192.1 - 1.4e-12 47.9 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR63192.1 - 2.9e-07 30.8 0.0 4.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR63192.1 - 1e-06 28.7 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR63192.1 - 9.9e-06 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 KIR63192.1 - 0.0006 20.0 1.0 0.00094 19.4 1.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sod_Ni PF09055.11 KIR63193.1 - 5.1e-46 156.4 0.1 5.8e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Phage_clamp_A PF16790.5 KIR63193.1 - 0.021 15.3 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage clamp loader A subunit ALC PF17527.2 KIR63193.1 - 0.074 12.7 0.1 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Phage ALC protein malic PF00390.19 KIR63194.1 - 5.6e-31 107.8 0.6 8.4e-29 100.6 0.0 2.8 2 1 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KIR63194.1 - 1.3e-21 77.0 4.6 5.2e-20 71.8 4.6 2.3 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ThiF PF00899.21 KIR63194.1 - 0.16 11.3 4.4 0.048 13.0 1.3 1.7 2 0 0 2 2 2 0 ThiF family ELFV_dehydrog PF00208.21 KIR63194.1 - 0.19 11.4 1.7 0.3 10.8 0.5 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Chlorophyllase2 PF12740.7 KIR63195.1 - 1.4e-09 37.3 0.0 2.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 KIR63195.1 - 1.3e-08 33.7 0.0 0.00025 19.7 0.0 2.2 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KIR63195.1 - 3.8e-08 32.9 0.8 0.013 14.7 0.0 3.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KIR63195.1 - 3.7e-07 29.5 0.0 6.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.18 KIR63195.1 - 9e-05 22.1 0.1 0.00016 21.3 0.1 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIR63195.1 - 0.0011 18.4 0.6 0.18 11.3 0.3 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KIR63195.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KIR63195.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Acetate_kinase PF00871.17 KIR63196.1 - 2.2e-131 438.2 0.0 5.5e-130 433.6 0.0 2.0 1 1 0 1 1 1 1 Acetokinase family FAO_M PF16350.5 KIR63196.1 - 0.0072 16.6 0.5 0.015 15.6 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain HCV_NS2 PF01538.18 KIR63196.1 - 0.17 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 PTA_PTB PF01515.19 KIR63197.1 - 4.5e-126 420.5 0.0 5.9e-126 420.1 0.0 1.1 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 KIR63197.1 - 1.9e-24 85.5 0.3 5.2e-24 84.1 0.3 1.8 1 0 0 1 1 1 1 DRTGG domain AAA_26 PF13500.6 KIR63197.1 - 6.8e-15 55.4 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIR63197.1 - 0.029 14.4 0.1 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain E1_dh PF00676.20 KIR63199.1 - 1.9e-57 194.5 0.0 4.9e-57 193.2 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component Transket_pyr PF02779.24 KIR63199.1 - 1.5e-54 184.3 0.0 3.6e-54 183.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain 2-oxoacid_dh PF00198.23 KIR63199.1 - 6.4e-54 182.9 0.0 1.1e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) OxoGdeHyase_C PF16870.5 KIR63199.1 - 4e-48 163.0 0.0 7.5e-48 162.1 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KIR63199.1 - 2.7e-12 46.1 0.6 5.1e-12 45.2 0.6 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus ABC2_membrane_4 PF12730.7 KIR63200.1 - 5.5e-07 29.7 9.1 9.7e-07 28.9 8.9 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 KIR63201.1 - 9.2e-26 91.0 0.0 1.3e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR63201.1 - 7.2e-12 45.7 0.0 6.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR63201.1 - 0.00033 21.2 0.0 0.00046 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR63201.1 - 0.00039 20.8 0.5 0.049 14.0 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIR63201.1 - 0.001 19.3 0.0 0.0029 17.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR63201.1 - 0.013 15.2 0.1 0.048 13.4 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4162 PF13732.6 KIR63201.1 - 0.015 16.0 0.0 0.025 15.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_30 PF13604.6 KIR63201.1 - 0.02 14.6 1.5 0.033 13.9 0.9 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR63201.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 KIR63201.1 - 0.25 11.0 0.0 0.47 10.1 0.0 1.3 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KIR63201.1 - 0.26 10.9 3.2 0.92 9.1 1.2 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4097 PF13349.6 KIR63203.1 - 7.4e-07 28.8 0.0 1.4e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Putative adhesin PadR PF03551.14 KIR63204.1 - 4.6e-20 71.4 0.2 8.9e-20 70.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family RTP PF02334.16 KIR63204.1 - 0.0029 18.2 0.0 0.0048 17.5 0.0 1.3 1 0 0 1 1 1 1 Replication terminator protein Fez1 PF06818.15 KIR63204.1 - 0.003 18.0 0.0 0.0046 17.4 0.0 1.2 1 0 0 1 1 1 1 Fez1 Mating_C PF12737.7 KIR63204.1 - 0.045 13.0 0.1 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 HTH_34 PF13601.6 KIR63204.1 - 0.049 13.8 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Mrr_N PF14338.6 KIR63204.1 - 0.056 13.6 0.5 18 5.5 0.1 3.0 3 0 0 3 3 3 0 Mrr N-terminal domain BLACT_WH PF17778.1 KIR63204.1 - 0.15 12.1 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain baeRF_family2 PF18844.1 KIR63204.1 - 0.2 11.7 0.2 0.2 11.7 0.2 2.4 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 HATPase_c PF02518.26 KIR63205.1 - 6.1e-23 81.5 0.0 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR63205.1 - 1.1e-18 67.0 1.1 1.1e-18 67.0 1.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR63205.1 - 1.6e-08 34.8 6.4 2.6e-08 34.1 2.2 3.5 2 1 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 KIR63205.1 - 3.5e-05 23.8 0.7 0.00022 21.2 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR63205.1 - 0.028 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3138 PF11336.8 KIR63205.1 - 1.3 7.5 3.6 2 6.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Trypsin_2 PF13365.6 KIR63206.1 - 2.1e-33 116.4 5.9 2.1e-33 116.4 5.9 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KIR63206.1 - 4.6e-22 78.1 0.9 4.6e-22 78.1 0.9 2.2 3 0 0 3 3 3 1 PDZ domain Trypsin PF00089.26 KIR63206.1 - 6.3e-12 45.8 3.1 1.2e-11 44.9 3.1 1.5 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KIR63206.1 - 5.1e-10 39.0 2.0 6e-09 35.6 0.9 3.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 KIR63206.1 - 1.3e-07 31.9 1.1 7.2e-07 29.5 0.6 2.5 2 1 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 KIR63206.1 - 0.0004 19.2 4.2 0.078 11.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Glycos_transf_1 PF00534.20 KIR63207.1 - 3.6e-21 75.5 0.0 5.9e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR63207.1 - 1.6e-15 57.7 0.1 4.9e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR63207.1 - 2e-10 41.0 8.0 2.4e-09 37.4 7.8 2.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 KIR63207.1 - 6.6e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KIR63207.1 - 4.2e-06 27.1 0.0 8.5e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR63207.1 - 6.6e-06 26.6 20.6 0.0002 21.8 17.8 3.2 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 KIR63207.1 - 0.45 10.2 1.9 0.59 9.8 0.5 1.8 1 1 0 2 2 2 0 Starch synthase catalytic domain Pkinase PF00069.25 KIR63208.1 - 5.2e-39 134.2 0.0 6.8e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR63208.1 - 4.4e-28 98.3 0.0 5.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR63208.1 - 7.5e-05 22.8 8.0 0.00071 19.6 0.0 3.1 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR63208.1 - 0.0011 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase TetR_C_21 PF17926.1 KIR63208.1 - 0.052 13.7 0.1 18 5.5 0.1 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RIO1 PF01163.22 KIR63208.1 - 0.25 10.9 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Patatin PF01734.22 KIR63209.1 - 4.3e-28 98.9 1.1 1.1e-27 97.6 1.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Acyltransferase PF01553.21 KIR63210.1 - 1.1e-07 31.6 0.1 2.7e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase CutA1 PF03091.15 KIR63211.1 - 7.7e-29 99.5 0.0 9.1e-29 99.2 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein FA_desaturase PF00487.24 KIR63212.1 - 1.1e-40 140.1 17.3 1.1e-40 140.1 17.3 1.8 1 1 1 2 2 2 1 Fatty acid desaturase ThrE PF06738.12 KIR63212.1 - 4.8 6.5 6.6 0.19 11.0 0.8 1.5 2 0 0 2 2 2 0 Putative threonine/serine exporter Pterin_4a PF01329.19 KIR63213.1 - 1.3e-24 86.2 0.0 1.4e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase CBX7_C PF17218.3 KIR63214.1 - 0.05 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 CBX family C-terminal motif Amidinotransf PF02274.17 KIR63215.1 - 2.8e-17 62.8 0.0 4.8e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 Amidinotransferase TetR_C_6 PF13977.6 KIR63215.1 - 0.17 12.1 5.0 2.5 8.3 0.2 2.5 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal NAD_binding_10 PF13460.6 KIR63216.1 - 1.1e-24 87.3 1.6 1.3e-24 87.1 1.6 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR63216.1 - 3.1e-08 33.5 3.0 3.7e-08 33.2 3.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIR63216.1 - 6.8e-08 32.3 1.1 8.3e-08 32.0 1.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KIR63216.1 - 7.6e-05 22.9 0.2 0.00011 22.4 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KIR63216.1 - 0.005 17.4 0.6 0.005 17.4 0.6 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 KIR63216.1 - 0.0086 15.2 0.5 0.012 14.8 0.5 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 KIR63216.1 - 0.033 14.3 0.4 0.05 13.7 0.4 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NTP_transf_3 PF12804.7 KIR63216.1 - 0.11 12.9 9.8 0.24 11.8 9.8 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain DFP PF04127.15 KIR63216.1 - 0.12 12.2 2.8 0.18 11.6 2.8 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein HxlR PF01638.17 KIR63217.1 - 1.4e-21 76.1 0.0 1.7e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 KIR63217.1 - 0.00027 20.8 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR_2 PF12802.7 KIR63217.1 - 0.00059 19.7 0.4 0.00088 19.1 0.4 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR63217.1 - 0.0011 19.4 0.0 0.0014 19.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 KIR63217.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family GntR PF00392.21 KIR63217.1 - 0.038 13.6 0.4 0.063 12.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PaaX PF07848.12 KIR63217.1 - 0.094 12.9 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 PaaX-like protein HTH_5 PF01022.20 KIR63217.1 - 0.17 11.8 0.1 0.61 10.0 0.0 2.0 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family APH_6_hur PF04655.14 KIR63218.1 - 2.9e-41 141.5 1.9 3.6e-41 141.2 1.9 1.1 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 KIR63218.1 - 0.076 12.9 8.5 0.19 11.6 8.5 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family HTH_AsnC-type PF13404.6 KIR63218.1 - 0.076 12.9 0.1 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DNA_pol_A_exoN PF18305.1 KIR63218.1 - 0.11 12.8 1.1 12 6.2 0.0 3.0 3 0 0 3 3 3 0 3' to 5' exonuclease C-terminal domain WGR PF05406.15 KIR63219.1 - 3.9e-15 55.7 0.0 6.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 WGR domain PQQ_2 PF13360.6 KIR63219.1 - 1.3e-13 51.1 2.0 4.2e-10 39.6 0.2 3.3 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KIR63219.1 - 2.7e-10 40.4 23.4 0.00069 20.0 0.1 7.5 8 1 0 8 8 8 3 PQQ-like domain PQQ PF01011.21 KIR63219.1 - 0.00056 19.7 9.9 0.67 10.0 0.1 5.9 6 0 0 6 6 6 1 PQQ enzyme repeat WD40_like PF17005.5 KIR63219.1 - 0.014 14.8 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KIR63219.1 - 0.081 13.8 3.4 8.7 7.4 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat GCS2 PF04107.13 KIR63220.1 - 6.6e-45 153.7 0.4 8e-45 153.4 0.4 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) GST_C_2 PF13410.6 KIR63220.1 - 0.033 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 60KD_IMP PF02096.20 KIR63221.1 - 3e-29 102.1 0.0 4e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein LapA_dom PF06305.11 KIR63221.1 - 2.4 8.0 4.2 2.3 8.1 1.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CBM_2 PF00553.19 KIR63222.1 - 8.7e-28 96.6 10.2 8.7e-28 96.6 10.2 3.0 3 1 0 3 3 3 1 Cellulose binding domain Glyco_hydro_18 PF00704.28 KIR63222.1 - 4.6e-09 36.4 0.2 4.8e-08 33.1 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM49 PF09478.10 KIR63222.1 - 0.00028 21.1 0.2 0.00074 19.8 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 fn3 PF00041.21 KIR63222.1 - 0.0013 19.0 0.3 0.0038 17.5 0.3 1.9 1 0 0 1 1 1 1 Fibronectin type III domain SNARE_assoc PF09335.11 KIR63223.1 - 6.6e-26 91.1 0.9 6.6e-26 91.1 0.9 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1349 PF07081.11 KIR63224.1 - 1.1e-54 184.9 0.0 1.2e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 KIR63224.1 - 0.0036 17.1 0.0 0.0042 16.8 0.0 1.1 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Alpha-amylase PF00128.24 KIR63225.1 - 7.4e-70 236.1 0.0 7.7e-69 232.8 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KIR63225.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 KIR63225.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain adh_short_C2 PF13561.6 KIR63226.1 - 7.8e-64 215.4 9.6 8.8e-64 215.3 9.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR63226.1 - 8.2e-53 178.8 6.0 1e-52 178.5 6.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR63226.1 - 6.6e-19 68.5 3.9 1e-18 67.9 3.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR63226.1 - 0.003 17.0 0.6 0.0049 16.3 0.6 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 7TMR-DISM_7TM PF07695.11 KIR63227.1 - 0.0027 17.7 1.5 0.0034 17.3 1.5 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF5134 PF17197.4 KIR63228.1 - 3.6 7.5 10.8 8.7 6.2 10.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) PhdYeFM_antitox PF02604.19 KIR63229.1 - 0.00028 20.6 0.5 0.00037 20.3 0.4 1.3 1 1 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system RrnaAD PF00398.20 KIR63230.1 - 2.7e-37 128.3 0.0 2.9e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIR63230.1 - 6.3e-05 23.6 0.0 0.00014 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR63230.1 - 0.0061 17.2 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR63230.1 - 0.038 14.7 0.0 0.072 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIR63230.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Erythro_esteras PF05139.14 KIR63231.1 - 2.4e-109 366.3 2.4 2.8e-109 366.1 2.4 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF2795 PF11387.8 KIR63232.1 - 2.8e-15 56.2 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) MMPL PF03176.15 KIR63233.1 - 2.2e-92 309.6 42.6 8.4e-60 202.4 17.6 2.3 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 KIR63233.1 - 0.00088 19.1 20.0 0.001 18.9 2.3 2.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation TLV_coat PF00429.19 KIR63233.1 - 0.0098 14.6 0.5 0.018 13.8 0.5 1.4 1 0 0 1 1 1 1 ENV polyprotein (coat polyprotein) DUF3385 PF11865.8 KIR63233.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) PEP_mutase PF13714.6 KIR63234.1 - 1.5e-75 253.7 3.0 1.8e-75 253.5 3.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TMP-TENI PF02581.17 KIR63234.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase Pantoate_transf PF02548.15 KIR63234.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase DNA_primase_S PF01896.19 KIR63235.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit FAD_binding_3 PF01494.19 KIR63236.1 - 1.2e-17 64.2 8.7 2.9e-09 36.6 0.5 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIR63236.1 - 0.00041 20.5 0.2 0.0015 18.8 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR63236.1 - 0.017 14.4 0.2 0.036 13.3 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIR63236.1 - 0.13 11.3 0.0 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase HTH_33 PF13592.6 KIR63237.1 - 1.6e-09 37.3 0.2 2.9e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 KIR63237.1 - 0.0027 18.3 1.6 0.004 17.7 0.3 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DUF305 PF03713.13 KIR63238.1 - 5.3e-43 146.8 3.7 6.3e-43 146.5 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 KIR63238.1 - 1e-06 29.1 0.0 1.1e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) MadM PF03818.13 KIR63238.1 - 0.93 9.4 4.2 1.8 8.5 4.2 1.4 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit DUF3105 PF11303.8 KIR63239.1 - 4.2e-45 153.1 0.1 6.2e-45 152.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) DALR_1 PF05746.15 KIR63240.1 - 7.5e-36 122.9 0.0 1.4e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KIR63240.1 - 9.7e-21 74.2 0.0 2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1d PF00750.19 KIR63240.1 - 2.8e-16 59.4 0.0 9.8e-16 57.6 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1g PF09334.11 KIR63240.1 - 1e-06 27.8 0.1 0.14 10.9 0.0 3.8 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIR63240.1 - 8.2e-05 21.0 0.0 0.00044 18.6 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KIR63240.1 - 0.037 12.9 0.0 2.8 6.8 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (K) MIT_C PF16565.5 KIR63240.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT Orn_Arg_deC_N PF02784.16 KIR63241.1 - 3e-59 200.4 0.0 3.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIR63241.1 - 1.1e-14 54.4 0.0 1.4e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Homoserine_dh PF00742.19 KIR63242.1 - 1e-66 224.1 0.2 1.5e-66 223.6 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KIR63242.1 - 2.9e-21 76.3 0.4 8.9e-21 74.7 0.1 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 KIR63242.1 - 2.1e-14 53.0 0.2 5.7e-14 51.6 0.2 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KIR63242.1 - 0.00098 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KIR63242.1 - 0.014 15.9 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain DUF1611_N PF17396.2 KIR63242.1 - 0.05 13.8 0.4 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain PALP PF00291.25 KIR63243.1 - 5.6e-72 242.6 9.2 6.5e-72 242.4 9.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.10 KIR63243.1 - 0.27 11.4 2.6 4.7 7.5 0.4 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACR_tran PF00873.19 KIR63244.1 - 3.2e-220 733.6 24.4 3.7e-220 733.4 24.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 KIR63244.1 - 4.1e-16 58.8 46.2 1.8e-09 37.0 14.4 3.3 4 1 0 4 4 4 2 MMPL family SecD_SecF PF02355.16 KIR63244.1 - 1.5e-07 31.0 32.0 0.00037 19.9 9.4 2.3 2 0 0 2 2 2 2 Protein export membrane protein Polysacc_deac_1 PF01522.21 KIR63245.1 - 5.3e-30 103.9 0.0 7.3e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase MFS_1 PF07690.16 KIR63246.1 - 9.6e-25 87.2 45.0 9.6e-25 87.2 45.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIR63246.1 - 4e-16 58.5 39.5 5.1e-16 58.2 39.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector PSI_8 PF00796.18 KIR63247.1 - 1.3 9.0 5.6 0.58 10.1 2.1 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Rho_RNA_bind PF07497.12 KIR63248.1 - 2.5e-29 100.9 0.1 5.1e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 KIR63248.1 - 8.1e-22 77.9 0.0 1.3e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 KIR63248.1 - 7.5e-11 41.8 0.0 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain NACHT PF05729.12 KIR63248.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TFIIA PF03153.13 KIR63248.1 - 5.6 6.9 10.1 8.1 6.3 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L31 PF01197.18 KIR63249.1 - 3.4e-32 110.5 0.9 3.8e-32 110.3 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 PCRF PF03462.18 KIR63250.1 - 4.2e-63 212.7 0.1 9.4e-63 211.6 0.0 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KIR63250.1 - 3.7e-42 142.9 0.8 8.1e-42 141.8 0.8 1.6 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 KIR63250.1 - 0.062 13.1 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 MIR domain MRP-63 PF14978.6 KIR63250.1 - 0.16 12.6 0.1 0.32 11.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 DUF4055 PF13264.6 KIR63250.1 - 0.56 10.4 4.0 0.82 9.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) GGDEF PF00990.21 KIR63251.1 - 2.3e-31 108.7 0.0 5e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain TPR_12 PF13424.6 KIR63251.1 - 0.72 10.2 27.3 0.31 11.3 3.6 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Sua5_yciO_yrdC PF01300.18 KIR63252.1 - 4.5e-38 130.5 0.0 5.1e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination LMWPc PF01451.21 KIR63253.1 - 2.4e-20 73.4 0.0 3.7e-16 59.8 0.0 2.4 1 1 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Transgly PF00912.22 KIR63254.1 - 8.3e-57 191.5 0.0 1.2e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KIR63254.1 - 1.4e-21 77.0 0.0 2.9e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain SHMT PF00464.19 KIR63255.1 - 5.6e-159 529.0 0.0 6.6e-159 528.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KIR63255.1 - 4.9e-08 32.6 0.1 7.5e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KIR63255.1 - 6.1e-07 28.9 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIR63255.1 - 0.00072 18.6 0.0 0.00099 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR63255.1 - 0.001 17.7 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIR63255.1 - 0.0081 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ATP-synt_I PF03899.15 KIR63256.1 - 0.004 17.5 13.7 0.004 17.5 13.7 1.4 1 1 0 1 1 1 1 ATP synthase I chain ArAE_2_N PF10337.9 KIR63256.1 - 0.67 8.9 4.5 0.89 8.5 4.5 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal ATPase_gene1 PF09527.10 KIR63257.1 - 2.8e-07 30.6 13.5 3.3e-07 30.4 13.5 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ATP-synt_A PF00119.20 KIR63258.1 - 3e-52 177.7 30.1 3.5e-52 177.4 30.1 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_C PF00137.21 KIR63259.1 - 2.4e-11 43.8 6.5 2.9e-11 43.5 6.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit C Abhydrolase_9_N PF15420.6 KIR63259.1 - 0.15 12.0 4.3 0.32 11.0 4.3 1.5 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus ATP-synt_B PF00430.18 KIR63260.1 - 5.6e-28 97.7 11.9 6.7e-28 97.4 11.9 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 KIR63260.1 - 0.0039 16.8 0.8 0.02 14.5 0.8 2.0 1 1 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3584 PF12128.8 KIR63260.1 - 0.0059 14.2 2.7 0.0066 14.0 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SurA_N_3 PF13624.6 KIR63260.1 - 0.0099 15.7 2.2 0.014 15.2 2.2 1.2 1 0 0 1 1 1 1 SurA N-terminal domain DUF2570 PF10828.8 KIR63260.1 - 0.024 14.4 0.3 0.046 13.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF997 PF06196.12 KIR63260.1 - 0.029 14.3 0.2 0.042 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF948 PF06103.11 KIR63260.1 - 0.031 14.5 0.6 0.082 13.2 0.1 1.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM184 PF15665.5 KIR63260.1 - 0.036 13.8 2.3 0.051 13.3 2.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Hemerythrin PF01814.23 KIR63260.1 - 0.091 13.4 4.3 0.099 13.3 2.2 1.9 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain YscO-like PF16789.5 KIR63260.1 - 0.3 11.1 8.2 3.1 7.8 1.4 2.1 1 1 1 2 2 2 0 YscO-like protein KfrA_N PF11740.8 KIR63260.1 - 1.7 9.4 20.5 0.4 11.4 10.9 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF2937 PF11157.8 KIR63260.1 - 3.4 7.4 8.9 0.36 10.5 2.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) CBP4 PF07960.11 KIR63260.1 - 3.8 7.4 5.2 49 3.8 5.2 2.4 1 1 0 1 1 1 0 CBP4 OSCP PF00213.18 KIR63261.1 - 1.9e-33 116.0 0.0 3.9e-29 102.0 0.0 2.0 2 0 0 2 2 2 2 ATP synthase delta (OSCP) subunit Acyl-CoA_dh_C PF12806.7 KIR63261.1 - 0.094 12.9 0.9 0.23 11.6 0.9 1.6 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like ATP-synt_ab PF00006.25 KIR63262.1 - 6.6e-67 225.3 0.0 9.2e-67 224.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KIR63262.1 - 9.4e-45 152.0 0.0 1.6e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KIR63262.1 - 3.9e-12 46.5 1.8 8.8e-12 45.4 1.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TniB PF05621.11 KIR63262.1 - 0.031 13.7 0.0 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KIR63262.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIR63262.1 - 0.11 11.8 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 KaiC ATP-synt PF00231.19 KIR63263.1 - 4.2e-88 295.7 0.0 4.8e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase FliG_C PF01706.16 KIR63263.1 - 0.57 10.4 4.3 0.4 10.9 0.6 2.1 2 0 0 2 2 2 0 FliG C-terminal domain HemY_N PF07219.13 KIR63263.1 - 5.8 7.2 7.8 3.5 7.9 3.2 2.3 2 0 0 2 2 2 0 HemY protein N-terminus ATP-synt_ab PF00006.25 KIR63264.1 - 2e-62 210.6 0.0 2.8e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIR63264.1 - 1.6e-22 79.8 0.1 4.6e-22 78.3 0.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 KIR63264.1 - 0.0012 18.7 0.4 0.0062 16.4 0.4 2.1 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 KIR63264.1 - 0.003 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 KIR63264.1 - 0.004 16.5 1.3 0.0084 15.5 1.3 1.5 1 0 0 1 1 1 1 KaiC AAA PF00004.29 KIR63264.1 - 0.0041 17.5 0.2 0.023 15.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIR63264.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KIR63264.1 - 0.047 14.0 0.1 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain LRV_FeS PF05484.11 KIR63264.1 - 0.097 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster NB-ARC PF00931.22 KIR63264.1 - 0.11 11.7 0.7 0.4 9.8 0.6 1.9 1 1 1 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KIR63264.1 - 0.19 12.2 0.0 0.78 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase LytR_cpsA_psr PF03816.14 KIR63265.1 - 7.6e-34 117.1 0.0 1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain ATP-synt_DE_N PF02823.16 KIR63266.1 - 1.2e-27 95.6 0.2 1.3e-27 95.5 0.2 1.0 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2550 PF10739.9 KIR63267.1 - 5.1e-42 142.9 3.0 5.8e-42 142.7 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2550) Glyoxalase_4 PF13669.6 KIR63268.1 - 1.7e-13 50.8 0.1 2.6e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KIR63268.1 - 0.0049 17.1 0.0 0.074 13.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cob_adeno_trans PF01923.18 KIR63269.1 - 1.4e-56 191.1 0.0 1.6e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase EPSP_synthase PF00275.20 KIR63270.1 - 1.2e-84 284.5 0.2 5.4e-84 282.3 0.2 1.8 1 1 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 3HCDH_N PF02737.18 KIR63271.1 - 9.6e-69 230.9 0.4 1.5e-68 230.3 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIR63271.1 - 1.1e-30 106.1 0.1 1.8e-29 102.2 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIR63271.1 - 0.00011 22.4 2.7 0.00012 22.3 0.6 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 KIR63271.1 - 0.0009 18.9 0.7 0.0097 15.5 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR63271.1 - 0.0069 15.6 0.2 0.01 15.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KIR63271.1 - 0.024 15.1 0.7 0.038 14.5 0.4 1.6 2 1 0 2 2 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 KIR63271.1 - 0.036 13.6 0.7 0.053 13.1 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KIR63271.1 - 0.042 14.1 2.4 0.046 14.0 0.7 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 KIR63271.1 - 0.048 13.6 2.2 0.16 12.0 2.2 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KIR63271.1 - 0.062 13.9 6.5 0.05 14.2 2.7 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 KIR63271.1 - 0.099 13.2 0.9 0.37 11.4 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 KIR63271.1 - 0.15 11.6 2.7 2.6 7.6 2.7 2.3 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ThiF PF00899.21 KIR63271.1 - 0.95 8.8 4.0 9.7 5.5 0.1 2.2 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 KIR63271.1 - 9.6 5.4 9.3 26 4.0 9.3 2.0 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC2_membrane PF01061.24 KIR63272.1 - 3.3e-24 85.5 18.0 3.3e-24 85.5 18.0 1.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR63272.1 - 8.6e-19 67.8 5.9 8.6e-19 67.8 5.9 2.0 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KIR63272.1 - 3.2e-13 49.6 10.2 2.1e-11 43.6 10.2 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR63272.1 - 1.5 8.8 14.1 0.035 14.0 7.3 1.8 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 KIR63273.1 - 4.1e-27 95.4 0.0 5.7e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR63273.1 - 4e-15 56.4 0.0 3.7e-09 36.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIR63273.1 - 6.2e-05 22.9 0.0 0.055 13.2 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 KIR63273.1 - 0.0053 16.5 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KIR63273.1 - 0.0072 16.5 0.4 0.43 10.8 0.1 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit KdpD PF02702.17 KIR63273.1 - 0.0082 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_23 PF13476.6 KIR63273.1 - 0.0091 16.5 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KIR63273.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KIR63273.1 - 0.04 13.6 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KIR63273.1 - 0.042 13.3 0.0 7 6.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KIR63273.1 - 0.043 13.5 0.0 8.7 6.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 KIR63273.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KIR63273.1 - 0.12 12.6 0.1 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIR63273.1 - 0.13 12.6 0.1 1.1 9.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIR63273.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MM_CoA_mutase PF01642.22 KIR63274.1 - 2.4e-130 435.5 0.0 3e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KIR63274.1 - 8.7e-17 61.3 1.5 8.7e-17 61.3 1.5 2.0 2 1 1 3 3 3 1 B12 binding domain DUF1540 PF07561.11 KIR63275.1 - 1.5e-08 34.8 11.0 0.00066 19.9 0.3 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1540) Polysacc_deac_1 PF01522.21 KIR63276.1 - 3.9e-23 81.7 0.0 7e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF1638 PF07796.11 KIR63276.1 - 0.15 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) DUF4126 PF13548.6 KIR63278.1 - 1.3e-54 184.6 19.4 1.5e-54 184.4 19.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) DUF3377 PF11857.8 KIR63278.1 - 0.0014 18.6 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF2569 PF10754.9 KIR63278.1 - 0.034 14.6 1.4 0.15 12.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4448 PF14610.6 KIR63278.1 - 0.063 13.0 1.9 0.093 12.5 0.7 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM100 PF16311.5 KIR63278.1 - 0.11 12.1 0.5 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 DUF3619 PF12279.8 KIR63278.1 - 0.6 10.4 3.0 0.93 9.8 0.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3619) NucS PF01939.16 KIR63279.1 - 2.5e-79 265.9 0.0 2.8e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Endonuclease NucS UPF0102 PF02021.17 KIR63279.1 - 0.0038 17.4 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DnaB_C PF03796.15 KIR63279.1 - 0.029 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mrr_cat PF04471.12 KIR63279.1 - 0.046 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Aldedh PF00171.22 KIR63280.1 - 2.8e-123 411.8 0.0 3.4e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_kinase PF01513.21 KIR63280.1 - 0.0049 16.1 0.1 0.0092 15.2 0.1 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Yop-YscD_cpl PF16697.5 KIR63281.1 - 2e-19 69.7 0.0 2.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KIR63281.1 - 7.4e-18 64.7 0.0 9.3e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 FHA domain TetR_C_28 PF17937.1 KIR63281.1 - 0.0082 16.6 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Abhydrolase_6 PF12697.7 KIR63282.1 - 3.5e-21 76.8 31.7 1.9e-20 74.4 31.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR63282.1 - 6.7e-16 58.7 0.1 1.5e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR63282.1 - 1.2e-15 57.5 0.1 2.6e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIR63282.1 - 0.0005 19.9 0.1 0.56 9.9 0.1 2.3 2 0 0 2 2 2 2 PGAP1-like protein Esterase PF00756.20 KIR63282.1 - 0.00075 19.2 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 KIR63282.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase FAM92 PF06730.11 KIR63282.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 FAM92 protein Thioesterase PF00975.20 KIR63282.1 - 0.068 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 KIR63282.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KIR63282.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KIR63282.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KIR63282.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family 3HCDH_N PF02737.18 KIR63283.1 - 3.7e-95 316.9 10.2 2.7e-61 206.6 0.5 3.1 2 1 1 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIR63283.1 - 2.3e-62 207.6 0.2 4.2e-30 104.2 0.1 2.8 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain F420_oxidored PF03807.17 KIR63283.1 - 0.00013 22.5 0.6 0.23 12.1 0.1 2.8 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIR63283.1 - 0.00081 19.6 0.5 0.00081 19.6 0.5 2.7 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KIR63283.1 - 0.0088 15.4 1.8 0.3 10.4 0.1 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KIR63283.1 - 0.011 15.0 0.9 0.054 12.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.12 KIR63283.1 - 0.013 16.1 0.5 0.089 13.5 0.2 2.6 3 1 0 3 3 2 0 Methyltransferase domain NAD_binding_7 PF13241.6 KIR63283.1 - 0.02 15.3 4.2 2.2 8.8 0.5 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Methyltransf_12 PF08242.12 KIR63283.1 - 0.055 14.2 0.1 0.35 11.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.18 KIR63283.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.2 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KIR63283.1 - 0.19 11.3 3.7 0.11 12.0 0.3 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rossmann-like PF10727.9 KIR63283.1 - 0.83 9.5 7.8 1.3 8.9 0.3 3.0 2 1 0 2 2 2 0 Rossmann-like domain DUF5330 PF17264.2 KIR63283.1 - 0.9 9.6 3.1 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5330) Shikimate_DH PF01488.20 KIR63283.1 - 0.91 9.6 3.6 14 5.8 0.2 2.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KIR63283.1 - 1.5 9.0 3.9 2.8 8.2 0.4 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Abhydrolase_6 PF12697.7 KIR63285.1 - 6.5e-05 23.6 9.2 9.8e-05 23.1 9.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR63285.1 - 0.0038 16.9 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DivIVA PF05103.13 KIR63287.1 - 1.4e-05 25.2 1.1 1.4e-05 25.2 1.1 6.0 1 1 4 6 6 6 3 DivIVA protein HU-CCDC81_bac_2 PF18175.1 KIR63287.1 - 0.58 10.1 2.2 1.8 8.5 0.2 2.8 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Glyoxalase_4 PF13669.6 KIR63288.1 - 2e-21 76.3 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KIR63288.1 - 9e-18 64.7 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KIR63288.1 - 3.7e-09 36.9 0.1 6.2e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KIR63288.1 - 0.065 14.0 0.0 0.11 13.3 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Thiolase_N PF00108.23 KIR63289.1 - 6e-100 333.9 0.7 7.8e-100 333.5 0.7 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR63289.1 - 9.6e-43 144.7 1.8 4.6e-42 142.5 1.4 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR63289.1 - 5.3e-07 29.5 0.9 6.6e-06 25.9 0.3 2.7 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIR63289.1 - 0.0011 18.7 0.5 0.25 11.2 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 KIR63289.1 - 0.0031 16.3 0.1 0.0073 15.0 0.1 1.6 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) MeaB PF03308.16 KIR63290.1 - 3.3e-94 314.8 7.1 4.4e-94 314.4 7.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KIR63290.1 - 4.1e-05 23.6 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_trans_4_4 PF13579.6 KIR63290.1 - 5.8e-05 23.6 3.6 5.8e-05 23.6 3.6 2.6 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain ParA PF10609.9 KIR63290.1 - 7.4e-05 22.3 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase cobW PF02492.19 KIR63290.1 - 8.9e-05 22.1 1.8 0.00078 19.1 1.8 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIR63290.1 - 0.00019 21.2 0.3 0.00019 21.2 0.3 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 KIR63290.1 - 0.00023 21.1 0.1 0.00073 19.5 0.1 1.8 1 0 0 1 1 1 1 NTPase SRP54 PF00448.22 KIR63290.1 - 0.00031 20.4 0.0 0.00077 19.1 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 KIR63290.1 - 0.00034 19.7 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 KIR63290.1 - 0.0004 20.9 0.2 0.0026 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR63290.1 - 0.00074 19.9 0.3 0.0019 18.6 0.1 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR63290.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF1611 PF07755.11 KIR63290.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1611_C) P-loop domain MMR_HSR1 PF01926.23 KIR63290.1 - 0.0035 17.4 0.3 0.013 15.6 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_transf_4 PF13439.6 KIR63290.1 - 0.0053 16.8 0.1 0.015 15.3 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Fer4_NifH PF00142.18 KIR63290.1 - 0.0057 16.1 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ATP_bind_1 PF03029.17 KIR63290.1 - 0.0066 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 KIR63290.1 - 0.007 16.7 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 KIR63290.1 - 0.0077 16.1 0.1 0.019 14.9 0.1 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 KIR63290.1 - 0.011 15.6 0.0 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.10 KIR63290.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 KIR63290.1 - 0.023 14.6 0.0 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 KIR63290.1 - 0.035 14.5 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KIR63290.1 - 0.043 13.8 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MipZ PF09140.11 KIR63290.1 - 0.046 13.0 2.7 0.069 12.4 0.3 2.4 2 1 0 2 2 2 0 ATPase MipZ Glyco_tranf_2_3 PF13641.6 KIR63290.1 - 0.047 13.6 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 AAA_31 PF13614.6 KIR63290.1 - 0.055 13.4 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KIR63290.1 - 0.098 12.4 0.7 1 9.0 0.1 2.3 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family VirC1 PF07015.11 KIR63290.1 - 0.12 11.7 0.0 0.55 9.5 0.0 1.9 1 1 0 1 1 1 0 VirC1 protein AAA_28 PF13521.6 KIR63290.1 - 0.13 12.5 1.7 0.26 11.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIR63290.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KIR63290.1 - 0.17 12.0 0.5 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIR63290.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Asp23 PF03780.13 KIR63291.1 - 1.4e-17 64.1 2.5 1.7e-17 63.8 2.5 1.1 1 0 0 1 1 1 1 Asp23 family, cell envelope-related function MM_CoA_mutase PF01642.22 KIR63292.1 - 1.3e-208 693.8 0.0 1.4e-208 693.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase TPR_20 PF14561.6 KIR63293.1 - 8.2e-21 74.1 3.1 8.2e-21 74.1 3.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.20 KIR63293.1 - 4.5e-10 39.4 0.0 7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TPR_19 PF14559.6 KIR63293.1 - 5.3e-05 23.6 18.7 0.00031 21.2 2.6 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 KIR63293.1 - 0.002 18.6 0.0 0.0057 17.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain TPR_12 PF13424.6 KIR63293.1 - 0.0029 17.9 0.9 5.8 7.3 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIR63293.1 - 0.005 17.6 17.9 0.013 16.2 2.0 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TraF PF13728.6 KIR63293.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein TrbC_Ftype PF09673.10 KIR63293.1 - 0.026 14.6 0.0 0.2 11.7 0.0 2.1 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein TPR_16 PF13432.6 KIR63293.1 - 0.044 14.4 13.5 0.044 14.4 13.5 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIR63293.1 - 0.063 13.4 0.9 0.26 11.5 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DSBA PF01323.20 KIR63293.1 - 0.068 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain KaiB PF07689.12 KIR63293.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiB domain Thioredoxin_8 PF13905.6 KIR63293.1 - 0.28 11.5 0.0 8.6 6.8 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like Transpeptidase PF00905.22 KIR63294.1 - 5.1e-44 150.7 0.0 6.4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 KIR63294.1 - 6.7e-18 65.7 0.0 1e-17 65.1 0.0 1.2 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MecA_N PF05223.11 KIR63294.1 - 2.1e-05 24.7 0.0 4.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain DUF3035 PF11233.8 KIR63294.1 - 0.076 13.3 1.4 0.24 11.7 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Bac_GDH PF05088.12 KIR63295.1 - 0 2174.0 0.0 0 2173.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 KIR63295.1 - 0.026 14.3 0.0 0.24 11.1 0.0 2.2 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sortase PF04203.13 KIR63296.1 - 2.1e-18 66.3 0.0 2.6e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Sortase domain Glyco_hydro_6 PF01341.17 KIR63297.1 - 2.9e-90 303.1 0.2 3.9e-90 302.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_2 PF00553.19 KIR63297.1 - 1e-28 99.6 13.3 1e-28 99.6 13.3 2.4 2 0 0 2 2 2 1 Cellulose binding domain NIT PF08376.10 KIR63300.1 - 2.8e-30 106.5 23.9 2.8e-30 106.5 23.9 2.4 2 1 1 3 3 3 1 Nitrate and nitrite sensing HATPase_c PF02518.26 KIR63300.1 - 4.9e-05 23.8 0.0 9.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR63300.1 - 5.9e-05 23.4 5.2 7e-05 23.1 1.9 3.0 2 0 0 2 2 2 1 HAMP domain DUF3040 PF11239.8 KIR63300.1 - 8.5 6.7 9.0 16 5.9 2.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Robl_LC7 PF03259.17 KIR63301.1 - 2.6e-24 84.8 1.2 3.6e-24 84.4 1.2 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain PNP_UDP_1 PF01048.20 KIR63301.1 - 0.011 14.9 0.8 0.013 14.8 0.8 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily ATP_bind_1 PF03029.17 KIR63302.1 - 1.2e-27 97.3 0.1 2.2e-25 89.8 0.1 2.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KIR63302.1 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIR63302.1 - 0.0063 16.8 0.3 0.013 15.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIR63302.1 - 0.015 15.0 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR63302.1 - 0.015 15.0 0.5 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KIR63302.1 - 0.02 15.4 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KIR63302.1 - 0.039 13.0 0.3 0.054 12.6 0.3 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KIR63302.1 - 0.053 14.1 0.4 0.11 13.0 0.4 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIR63302.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KIR63302.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.12 KIR63302.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KIR63302.1 - 0.13 12.2 0.4 0.24 11.3 0.4 1.5 1 1 0 1 1 1 0 RsgA GTPase Roc PF08477.13 KIR63302.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KIR63302.1 - 0.14 11.7 0.2 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 KIR63302.1 - 0.3 10.9 0.1 0.43 10.4 0.1 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Lactonase PF10282.9 KIR63303.1 - 1.6e-97 326.9 0.0 1.8e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.21 KIR63303.1 - 0.00026 20.9 1.3 4.5 7.5 0.2 3.7 3 0 0 3 3 3 2 NHL repeat SGL PF08450.12 KIR63303.1 - 0.0077 15.8 0.0 3.5 7.1 0.0 3.3 2 1 2 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region SBP_bac_11 PF13531.6 KIR63304.1 - 1.7e-26 93.4 12.0 2.7e-26 92.8 12.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein VWA PF00092.28 KIR63304.1 - 3.6e-15 56.7 0.0 5.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIR63304.1 - 1.4e-09 38.5 0.0 3.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIR63304.1 - 5e-05 23.3 0.0 0.00016 21.7 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KIR63304.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus Bac_transf PF02397.16 KIR63305.1 - 6.3e-65 218.2 0.0 9.5e-65 217.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 KIR63305.1 - 4e-07 30.2 1.3 9.8e-07 28.9 0.1 2.2 1 1 1 2 2 2 1 CoA-binding domain SpoIIE PF07228.12 KIR63306.1 - 3.4e-32 111.9 1.6 6.2e-32 111.1 1.6 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) B12-binding PF02310.19 KIR63307.1 - 6.3e-19 68.2 0.3 6.3e-19 68.2 0.3 2.0 3 0 0 3 3 3 1 B12 binding domain B12-binding_2 PF02607.17 KIR63307.1 - 3.8e-09 36.9 2.2 1.3e-08 35.2 2.2 1.9 1 0 0 1 1 1 1 B12 binding domain ROK PF00480.20 KIR63308.1 - 3.1e-41 141.8 0.0 4.4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR63308.1 - 3.7e-05 23.5 1.0 3.7e-05 23.5 1.0 3.0 3 0 0 3 3 3 1 MarR family HTH_IclR PF09339.10 KIR63308.1 - 0.00012 21.9 2.1 0.00072 19.3 0.1 2.8 2 1 0 2 2 2 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR63308.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain AP_endonuc_2 PF01261.24 KIR63309.1 - 2.6e-28 98.9 0.2 3.7e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MIT PF04212.18 KIR63309.1 - 0.046 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain FGGY_N PF00370.21 KIR63310.1 - 3.3e-42 144.8 0.0 4.2e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIR63310.1 - 5.5e-26 91.5 1.6 1.3e-25 90.3 1.6 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 KIR63310.1 - 0.042 12.0 0.2 0.059 11.6 0.2 1.1 1 0 0 1 1 1 0 Hsp70 protein Peripla_BP_3 PF13377.6 KIR63311.1 - 3e-36 125.3 3.4 2e-35 122.6 0.2 2.8 3 1 0 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR63311.1 - 5.3e-25 88.4 0.0 6.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR63311.1 - 3.1e-17 62.1 2.9 3.5e-17 61.9 0.8 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR63311.1 - 6.3e-10 39.0 0.0 1.5e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR63311.1 - 0.0076 16.6 1.3 0.0076 16.6 1.3 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR63311.1 - 0.037 14.1 0.1 0.076 13.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_Crp_2 PF13545.6 KIR63311.1 - 0.14 12.1 1.5 0.7 9.9 0.1 2.7 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain BPD_transp_1 PF00528.22 KIR63312.1 - 4.7e-17 62.3 16.7 4.7e-17 62.3 16.7 2.3 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component YfhO PF09586.10 KIR63312.1 - 0.27 9.4 7.2 0.057 11.6 3.9 1.4 1 1 0 1 1 1 0 Bacterial membrane protein YfhO BPD_transp_1 PF00528.22 KIR63313.1 - 7.5e-19 68.2 13.0 7.5e-19 68.2 13.0 2.8 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component Wzz PF02706.15 KIR63313.1 - 0.015 15.6 2.1 0.015 15.6 2.1 2.9 3 0 0 3 3 3 0 Chain length determinant protein SBP_bac_1 PF01547.25 KIR63314.1 - 9.5e-19 68.5 12.3 1.4e-18 67.9 12.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Peptidase_M23 PF01551.22 KIR63315.1 - 3e-25 88.3 1.4 3e-25 88.3 1.4 1.8 2 0 0 2 2 2 1 Peptidase family M23 SH3_3 PF08239.11 KIR63315.1 - 1.4e-06 28.5 1.3 1.4e-06 28.5 1.3 2.7 3 0 0 3 3 3 1 Bacterial SH3 domain Metallophos PF00149.28 KIR63316.1 - 6.4e-09 36.6 0.6 2.4e-08 34.7 0.5 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR63316.1 - 5e-08 33.3 0.0 3.5e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain BON PF04972.17 KIR63317.1 - 0.0047 17.2 0.0 0.0061 16.8 0.0 1.2 1 0 0 1 1 1 1 BON domain NTP_transf_5 PF14907.6 KIR63318.1 - 4.9e-13 49.3 0.1 5.9e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2204 PF09970.9 KIR63318.1 - 3.6e-05 23.5 0.0 5.6e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Nsp3_PL2pro PF12124.8 KIR63318.1 - 0.0071 16.1 0.3 0.07 12.9 0.1 2.4 1 1 1 2 2 2 1 Coronavirus polyprotein cleavage domain DUF2007 PF09413.10 KIR63318.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Sigma70_r3 PF04539.16 KIR63319.1 - 5.7e-25 87.2 0.7 8.3e-23 80.3 0.2 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 KIR63319.1 - 3.4e-22 78.0 0.5 8.1e-22 76.8 0.5 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR63319.1 - 7.7e-14 50.9 9.8 1e-12 47.4 2.2 2.9 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 KIR63319.1 - 2.3e-10 40.3 0.0 5.7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 KORA PF16509.5 KIR63319.1 - 0.051 13.8 0.1 7.1 7.0 0.0 2.7 2 1 0 2 2 2 0 TrfB plasmid transcriptional repressor Tox-MPTase3 PF15639.6 KIR63319.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 3 NLPC_P60 PF00877.19 KIR63320.1 - 1.8e-20 72.9 0.0 3.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family DUF3450 PF11932.8 KIR63320.1 - 0.0027 17.1 4.5 0.026 13.8 1.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF948 PF06103.11 KIR63320.1 - 0.005 17.1 1.2 0.16 12.2 0.1 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 KIR63320.1 - 0.013 15.5 2.3 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Amidase_5 PF05382.13 KIR63320.1 - 0.016 15.2 0.1 0.051 13.5 0.1 1.7 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase CLZ PF16526.5 KIR63320.1 - 0.032 14.6 6.6 2.5 8.5 2.0 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CHAP PF05257.16 KIR63320.1 - 0.037 14.6 0.5 0.11 13.1 0.1 2.0 2 1 0 2 2 1 0 CHAP domain Dor1 PF04124.12 KIR63320.1 - 0.039 12.6 5.2 0.14 10.8 2.2 2.0 2 0 0 2 2 2 0 Dor1-like family DUF4446 PF14584.6 KIR63320.1 - 0.066 13.2 0.4 9.2 6.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) LRAT PF04970.13 KIR63320.1 - 0.083 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF1664 PF07889.12 KIR63320.1 - 0.089 12.8 1.8 8.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GCN5L1 PF06320.13 KIR63320.1 - 0.1 12.8 3.0 0.16 12.1 0.7 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) AAA_13 PF13166.6 KIR63320.1 - 0.18 10.4 2.9 0.5 9.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 KIR63320.1 - 0.2 11.5 10.9 0.26 11.1 0.2 2.5 2 1 0 2 2 2 0 Septum formation initiator Mer2 PF09074.10 KIR63320.1 - 0.21 11.4 1.7 0.83 9.4 1.7 1.8 1 1 0 1 1 1 0 Mer2 FUSC PF04632.12 KIR63320.1 - 0.69 8.4 8.2 0.88 8.0 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 KIR63320.1 - 1.7 9.2 9.2 14 6.3 0.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region KxDL PF10241.9 KIR63320.1 - 2.1 8.7 7.2 21 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein CENP-H PF05837.12 KIR63320.1 - 2.2 8.7 9.5 1.8 9.0 0.3 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4164 PF13747.6 KIR63320.1 - 2.4 8.5 12.5 15 5.9 7.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ABC_tran_CTD PF16326.5 KIR63320.1 - 3.2 8.1 10.7 27 5.1 4.7 3.0 2 1 0 3 3 3 0 ABC transporter C-terminal domain ATG16 PF08614.11 KIR63320.1 - 3.6 7.8 15.7 12 6.1 7.5 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.20 KIR63320.1 - 3.7 7.5 6.5 10 6.1 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit CENP-Q PF13094.6 KIR63320.1 - 9.3 6.4 11.2 7.5 6.7 1.1 2.2 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3817 PF12823.7 KIR63321.1 - 3.7e-30 104.6 3.8 4.2e-30 104.4 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) UPF0014 PF03649.13 KIR63321.1 - 0.011 15.2 0.4 0.012 15.0 0.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) DUF5337 PF17272.2 KIR63321.1 - 1.7 8.5 6.4 0.21 11.4 0.8 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Sdh_cyt PF01127.22 KIR63322.1 - 0.68 10.0 5.3 1.1 9.4 5.3 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Leader_Trp PF08255.11 KIR63322.1 - 0.72 10.0 5.6 8.6 6.6 0.6 2.6 2 0 0 2 2 2 0 Trp-operon Leader Peptide SURF1 PF02104.15 KIR63322.1 - 1.5 9.0 5.5 6.5 7.0 5.4 2.2 1 1 0 1 1 1 0 SURF1 family Polyketide_cyc2 PF10604.9 KIR63324.1 - 4.2e-06 27.1 4.7 0.0089 16.3 0.9 2.1 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIR63324.1 - 0.0032 17.7 0.4 0.022 15.0 0.3 2.0 1 1 1 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 KIR63324.1 - 0.029 14.6 0.4 0.14 12.4 0.4 1.9 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ADC PF06314.11 KIR63324.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) DUF1360 PF07098.11 KIR63325.1 - 2.1e-38 130.4 0.0 5.3e-38 129.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1360) DAHP_synth_1 PF00793.20 KIR63329.1 - 3.5e-92 308.2 0.0 4.3e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Peptidase_M16 PF00675.20 KIR63331.1 - 1.1e-22 80.6 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIR63331.1 - 1.4e-21 77.3 0.0 2.7e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_C PF05193.21 KIR63332.1 - 1.6e-12 47.8 0.0 1.5e-11 44.7 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIR63332.1 - 1.8e-08 34.5 0.0 2.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Semialdhyde_dhC PF02774.18 KIR63333.1 - 2e-50 171.4 0.0 2.7e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KIR63333.1 - 1.2e-31 109.7 0.1 2.3e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 KIR63333.1 - 0.15 11.6 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain CBS PF00571.28 KIR63334.1 - 2.6e-22 79.0 6.9 2.6e-11 43.8 0.2 2.2 2 0 0 2 2 2 2 CBS domain GAF PF01590.26 KIR63334.1 - 0.0068 17.0 0.2 0.0084 16.7 0.2 1.1 1 0 0 1 1 1 1 GAF domain SCP2 PF02036.17 KIR63335.1 - 5.6e-14 52.5 0.0 6.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family MDMPI_C PF07398.11 KIR63335.1 - 0.055 14.3 1.4 0.077 13.9 1.4 1.3 1 0 0 1 1 1 0 MDMPI C-terminal domain Anemone_cytotox PF06369.12 KIR63335.1 - 0.07 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Alkyl_sulf_C PF14864.6 KIR63335.1 - 0.16 12.2 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Acyltransferase PF01553.21 KIR63336.1 - 8.1e-29 100.0 0.0 1.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 KIR63336.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Melibiase PF02065.18 KIR63337.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 Melibiase Acetyltransf_1 PF00583.25 KIR63338.1 - 1.8e-09 37.8 0.0 2.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIR63338.1 - 9.2e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIR63338.1 - 0.00038 20.8 0.0 0.00053 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR63338.1 - 0.0057 16.6 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR63338.1 - 0.012 16.3 0.1 0.018 15.8 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain RibD_C PF01872.17 KIR63339.1 - 2.7e-17 63.3 0.1 4.5e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 RibD C-terminal domain DUF402 PF04167.13 KIR63340.1 - 6.4e-13 48.7 2.9 1.1e-12 47.9 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF402) DUF488 PF04343.13 KIR63341.1 - 5.3e-31 107.7 0.2 6.2e-31 107.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 AOC_like PF18678.1 KIR63342.1 - 0.3 10.7 2.4 0.3 10.7 0.1 2.1 1 1 1 2 2 2 0 Allene oxide cyclase barrel like domain Glyco_hydr_30_2 PF14587.6 KIR63343.1 - 8.1e-17 61.9 1.5 3.7e-14 53.1 0.0 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KIR63343.1 - 5.3e-12 45.8 0.1 1.3e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KIR63343.1 - 8.9e-09 35.0 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 KIR63343.1 - 2.5e-08 33.3 0.2 4.7e-08 32.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain PepSY_2 PF13670.6 KIR63343.1 - 0.11 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF397 PF04149.12 KIR63344.1 - 9.1e-24 83.3 0.2 1e-23 83.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KIR63345.1 - 4.5e-11 42.9 3.4 8.7e-11 42.0 0.5 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain FbpC_C_terminal PF17845.1 KIR63345.1 - 0.0096 16.0 0.8 0.08 13.1 0.1 2.7 3 1 0 3 3 3 1 FbpC C-terminal regulatory nucleotide binding domain HTH_19 PF12844.7 KIR63345.1 - 0.12 12.4 0.1 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Inositol_P PF00459.25 KIR63347.1 - 3.6e-33 115.2 1.0 5e-33 114.8 1.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family RibD_C PF01872.17 KIR63348.1 - 2e-20 73.5 0.0 2.9e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Anti-TRAP PF15777.5 KIR63349.1 - 0.023 14.7 5.2 0.034 14.1 5.2 1.3 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Prim-Pol PF09250.11 KIR63352.1 - 7.8e-41 140.1 7.3 7.4e-40 136.9 4.4 2.1 2 0 0 2 2 2 2 Bifunctional DNA primase/polymerase, N-terminal TrwB_AAD_bind PF10412.9 KIR63354.1 - 0.19 10.6 0.3 0.42 9.5 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2737 PF10930.8 KIR63357.1 - 0.039 13.5 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) FtsK_gamma PF09397.10 KIR63357.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain ChpA-C PF03777.13 KIR63357.1 - 0.12 12.3 0.0 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 ChpA-C Epimerase PF01370.21 KIR63359.1 - 1.8e-09 37.4 0.1 3.9e-08 33.0 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR63359.1 - 0.0023 17.1 0.0 0.65 9.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain SSI PF00720.17 KIR63359.1 - 0.048 13.6 0.3 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Subtilisin inhibitor-like UPF0052 PF01933.18 KIR63359.1 - 0.24 10.6 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Phage_integrase PF00589.22 KIR63361.1 - 2.9e-20 72.8 0.1 7.2e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 Phage integrase family GntR PF00392.21 KIR63361.1 - 1.5e-14 53.4 0.6 3.6e-14 52.2 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Phage_int_SAM_3 PF14659.6 KIR63361.1 - 1.9e-05 24.8 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain HTH_41 PF14502.6 KIR63361.1 - 0.00029 20.4 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR63361.1 - 0.019 14.9 0.2 0.019 14.9 0.2 3.6 5 0 0 5 5 5 0 MarR family HTH_24 PF13412.6 KIR63361.1 - 0.022 14.3 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Hydrolase_4 PF12146.8 KIR63362.1 - 1e-22 80.6 0.1 5.2e-22 78.3 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIR63362.1 - 2.9e-08 34.6 18.8 2.9e-08 34.6 18.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR63362.1 - 3.1e-06 27.0 0.2 4.5e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIR63362.1 - 0.0015 18.3 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PUA_2 PF14306.6 KIR63362.1 - 0.066 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 PUA-like domain DUF1749 PF08538.10 KIR63362.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Ribosomal_S30AE PF02482.19 KIR63363.1 - 2.6e-06 28.1 0.1 3.4e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein TGF_beta_GS PF08515.12 KIR63363.1 - 0.075 12.5 0.3 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif GATase_3 PF07685.14 KIR63364.1 - 2.3e-47 161.1 0.0 3.1e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 KIR63364.1 - 3.7e-20 72.3 0.0 6.4e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KIR63364.1 - 3.1e-16 59.8 0.0 1.4e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain SNO PF01174.19 KIR63364.1 - 0.00025 21.0 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase PF00117.28 KIR63364.1 - 0.0014 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KIR63364.1 - 0.0017 18.1 0.0 0.0058 16.4 0.1 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KIR63364.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 DUF4235 PF14019.6 KIR63365.1 - 0.014 15.4 1.4 0.014 15.4 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) Peptidase_M20 PF01546.28 KIR63366.1 - 6.1e-35 120.8 0.9 1.6e-34 119.4 0.5 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIR63366.1 - 1.1e-18 67.1 0.0 1.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DNA_ligase_A_M PF01068.21 KIR63368.1 - 5.2e-38 130.7 0.0 7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KIR63368.1 - 3e-12 47.0 0.1 1e-11 45.3 0.1 2.0 1 1 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 KIR63368.1 - 1.7e-10 41.5 0.0 6.3e-08 33.1 0.0 2.5 1 1 2 3 3 3 2 DNA ligase N terminus RNA_ligase PF09414.10 KIR63368.1 - 7.2e-07 29.7 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA ligase SURF1 PF02104.15 KIR63369.1 - 4e-31 108.6 0.2 4e-31 108.6 0.2 1.3 2 0 0 2 2 2 1 SURF1 family CbiA PF01656.23 KIR63370.1 - 2.1e-12 47.2 0.0 3.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GATase_3 PF07685.14 KIR63370.1 - 3e-10 40.0 0.0 4.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 KIR63370.1 - 5.6e-07 29.6 0.0 6.7e-05 22.8 0.0 2.4 3 0 0 3 3 3 2 AAA domain Transgly PF00912.22 KIR63371.1 - 3.4e-59 199.3 0.7 5.1e-59 198.7 0.7 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 KIR63371.1 - 4.8e-30 104.8 1.2 9.8e-30 103.8 1.2 1.5 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain MID_pPIWI_RE PF18157.1 KIR63371.1 - 0.084 13.2 0.1 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 MID domain of pPIWI_RE Aminotran_1_2 PF00155.21 KIR63372.1 - 8.1e-32 110.8 0.0 1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DBI_PRT PF02277.17 KIR63373.1 - 5.7e-125 416.9 13.0 6.5e-125 416.7 13.0 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase TsaE PF02367.17 KIR63373.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TP_methylase PF00590.20 KIR63374.1 - 2.8e-45 154.9 4.8 2.8e-45 154.9 4.8 2.1 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KIR63374.1 - 1.7e-21 76.6 0.0 4.4e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Trehalose_PPase PF02358.16 KIR63375.1 - 1.6e-35 122.3 0.0 2.4e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_hydro_15 PF00723.21 KIR63375.1 - 3.3e-35 121.7 0.0 1.2e-32 113.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPR_14 PF13428.6 KIR63375.1 - 0.013 16.3 3.8 5.7 8.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIR63375.1 - 0.018 15.7 3.9 11 6.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIR63375.1 - 0.023 15.2 0.2 2.3 8.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Hydrolase_3 PF08282.12 KIR63375.1 - 0.072 12.8 0.0 6.4 6.4 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_4 PF07721.14 KIR63375.1 - 0.29 11.9 11.9 2.5 9.0 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_20 PF00982.21 KIR63376.1 - 1.6e-144 482.2 0.0 1.9e-144 481.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KIR63376.1 - 1.3e-05 24.8 0.1 0.00031 20.3 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR63376.1 - 0.00036 21.0 0.5 0.00086 19.7 0.5 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 RHH_5 PF07878.11 KIR63377.1 - 0.0073 16.2 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF505 PF04458.12 KIR63377.1 - 0.047 12.1 0.1 0.047 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) ABC_tran PF00005.27 KIR63378.1 - 4.8e-49 166.4 0.0 1.7e-25 90.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR63378.1 - 2.5e-19 70.2 5.9 2.3e-05 24.4 0.0 4.7 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KIR63378.1 - 1.2e-12 47.7 9.9 5.1e-12 45.7 5.1 2.6 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 KIR63378.1 - 2.5e-09 36.9 2.8 0.25 10.8 0.2 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR63378.1 - 4.3e-06 26.4 0.5 0.048 13.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIR63378.1 - 1e-05 25.6 0.3 0.14 12.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KIR63378.1 - 3.9e-05 24.1 0.6 0.31 11.4 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIR63378.1 - 7.2e-05 22.8 0.3 0.16 11.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KIR63378.1 - 0.00011 22.8 0.2 0.52 10.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KIR63378.1 - 0.00012 22.3 0.4 0.32 11.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIR63378.1 - 0.00014 22.4 3.6 0.0019 18.7 1.2 3.3 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 KIR63378.1 - 0.00053 19.8 1.2 0.62 9.7 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIR63378.1 - 0.00055 19.8 1.7 1.2 8.8 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 KIR63378.1 - 0.0014 18.3 0.2 1.2 8.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KIR63378.1 - 0.0016 18.6 0.4 1.5 9.1 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 KIR63378.1 - 0.0038 17.4 0.4 8.1 6.8 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KIR63378.1 - 0.0056 17.1 0.9 0.81 10.1 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIR63378.1 - 0.012 15.6 0.7 0.47 10.3 0.1 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIR63378.1 - 0.022 13.9 3.3 0.044 13.0 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain AAA_14 PF13173.6 KIR63378.1 - 0.026 14.6 0.4 0.6 10.1 0.1 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KIR63378.1 - 0.031 14.2 1.7 1.4 8.8 0.4 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KIR63378.1 - 0.049 13.2 1.6 4.2 6.9 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KIR63378.1 - 0.054 13.5 2.9 0.55 10.3 0.0 2.7 3 1 0 3 3 2 0 Dynamin family AAA_33 PF13671.6 KIR63378.1 - 0.077 13.2 4.6 0.95 9.6 0.0 3.0 3 1 0 3 3 2 0 AAA domain DLIC PF05783.11 KIR63378.1 - 0.084 11.7 0.2 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_27 PF13514.6 KIR63378.1 - 0.089 12.4 5.5 2.5 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KIR63378.1 - 0.1 13.0 0.6 12 6.4 0.1 2.4 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 KIR63378.1 - 0.12 11.9 0.5 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KIR63378.1 - 0.18 11.5 0.6 7.7 6.2 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ISG65-75 PF11727.8 KIR63378.1 - 0.2 10.8 4.1 0.13 11.4 0.3 2.0 2 0 0 2 2 2 0 Invariant surface glycoprotein MeaB PF03308.16 KIR63378.1 - 0.21 10.5 0.7 10 5.0 0.2 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KIR63378.1 - 0.32 11.2 3.9 10 6.4 0.1 3.1 3 1 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KIR63378.1 - 0.33 10.9 2.4 1.6 8.6 1.0 2.4 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KIR63378.1 - 0.38 10.3 1.9 14 5.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.6 KIR63378.1 - 0.48 9.0 3.0 28 3.2 0.1 3.6 4 0 0 4 4 4 0 AAA domain MRP-L46 PF11788.8 KIR63378.1 - 1 10.1 4.2 0.39 11.5 1.1 1.8 2 0 0 2 2 1 0 39S mitochondrial ribosomal protein L46 4HBT_2 PF13279.6 KIR63379.1 - 2.1e-11 44.4 0.0 2.8e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KIR63379.1 - 1.6e-09 38.0 0.7 1.4e-07 31.8 0.7 2.2 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KIR63379.1 - 8e-07 28.6 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase YbjN PF10722.9 KIR63380.1 - 4.2e-18 65.6 0.2 5.6e-18 65.2 0.2 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator Bac_globin PF01152.21 KIR63381.1 - 7.5e-36 122.9 0.0 8.6e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin MFS_1 PF07690.16 KIR63382.1 - 1.1e-15 57.4 49.6 1.5e-11 43.9 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MS_channel PF00924.18 KIR63383.1 - 8.3e-34 116.9 0.0 1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Phage_holin_3_3 PF16083.5 KIR63383.1 - 0.019 15.0 0.5 0.058 13.5 0.5 1.8 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III SH3_4 PF06347.13 KIR63383.1 - 0.032 14.1 0.6 0.89 9.4 0.3 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain CopD PF05425.13 KIR63383.1 - 1.2 9.6 7.7 8.8 6.8 7.1 2.6 1 1 0 1 1 1 0 Copper resistance protein D DUF4111 PF13427.6 KIR63384.1 - 9.9e-10 38.5 0.2 1.6e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) NTP_transf_2 PF01909.23 KIR63384.1 - 3e-05 24.2 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIR63384.1 - 0.00014 21.9 0.0 0.00029 20.9 0.0 1.6 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase MdcG PF10620.9 KIR63384.1 - 0.027 14.2 0.8 0.077 12.8 0.8 1.7 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Adenyl_cycl_N PF12633.7 KIR63384.1 - 0.21 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase NT domain Sortase PF04203.13 KIR63385.1 - 1.9e-16 60.0 0.0 2.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Sortase domain HTH_AsnC-type PF13404.6 KIR63386.1 - 1.5e-18 66.3 1.6 2.5e-18 65.6 1.6 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR63386.1 - 2.2e-17 62.3 0.0 3.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KIR63386.1 - 9.8e-09 35.1 0.0 2.4e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 KIR63386.1 - 9.8e-08 31.8 0.2 1.6e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KIR63386.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR63386.1 - 5.6e-05 23.1 0.2 0.00011 22.2 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KIR63386.1 - 0.0022 18.1 0.3 0.0071 16.5 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 KIR63386.1 - 0.0064 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 KIR63386.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 KIR63386.1 - 0.015 15.1 0.4 0.038 13.8 0.4 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_1 PF00126.27 KIR63386.1 - 0.026 14.5 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Crp_2 PF13545.6 KIR63386.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_27 PF13463.6 KIR63386.1 - 0.042 14.4 0.1 0.07 13.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_23 PF13384.6 KIR63386.1 - 0.063 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain LexA_DNA_bind PF01726.16 KIR63386.1 - 0.088 12.6 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 LexA DNA binding domain HTH_11 PF08279.12 KIR63386.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 HTH domain Trp_dioxygenase PF03301.13 KIR63387.1 - 2.5e-52 178.4 0.0 2.8e-50 171.6 0.0 2.7 1 1 0 1 1 1 1 Tryptophan 2,3-dioxygenase FAD_binding_3 PF01494.19 KIR63388.1 - 3e-26 92.5 0.0 3.9e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIR63388.1 - 8.6e-09 35.5 0.1 2.9e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR63388.1 - 3.5e-08 33.4 0.8 3.8e-06 26.7 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR63388.1 - 7e-05 23.3 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR63388.1 - 0.00011 21.6 0.0 0.0003 20.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR63388.1 - 0.00029 20.1 0.0 0.00064 18.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIR63388.1 - 0.00032 19.9 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KIR63388.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KIR63388.1 - 0.0034 16.5 0.1 0.018 14.1 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KIR63388.1 - 0.0037 17.2 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIR63388.1 - 0.017 13.9 0.0 0.041 12.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 KIR63388.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KIR63388.1 - 0.076 13.2 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_oxidored PF12831.7 KIR63388.1 - 0.081 12.3 1.0 0.33 10.2 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase RELT PF12606.8 KIR63388.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 FAA_hydrolase PF01557.18 KIR63389.1 - 4.7e-08 33.0 0.0 6.7e-08 32.5 0.0 1.2 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ribonuc_L-PSP PF01042.21 KIR63391.1 - 5.1e-24 84.6 0.0 6.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP 3-HAO PF06052.12 KIR63392.1 - 4.2e-47 159.6 0.0 4.6e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KIR63392.1 - 5.8e-06 25.9 0.4 9.7e-06 25.2 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_8 PF13621.6 KIR63392.1 - 0.00016 21.5 0.0 0.00019 21.2 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_3 PF05899.12 KIR63392.1 - 0.0052 16.5 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Terminase_GpA PF05876.12 KIR63392.1 - 0.0055 15.3 0.1 0.007 15.0 0.1 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) zf-NADH-PPase PF09297.11 KIR63392.1 - 0.0056 16.3 1.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KIR63392.1 - 0.0081 15.8 2.2 0.33 10.7 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIR63392.1 - 0.011 15.1 2.4 0.64 9.5 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain AraC_binding PF02311.19 KIR63392.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Cys_rich_KTR PF14205.6 KIR63392.1 - 0.015 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR DZR PF12773.7 KIR63392.1 - 0.019 14.9 2.4 0.15 12.1 2.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KIR63392.1 - 0.03 14.2 1.1 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-IS66 PF13005.7 KIR63392.1 - 0.049 14.0 3.0 1.2 9.6 0.1 2.7 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Zn-ribbon_8 PF09723.10 KIR63392.1 - 0.06 13.5 0.3 3.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KIR63392.1 - 0.07 13.0 0.6 0.07 13.0 0.6 1.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Cupin_1 PF00190.22 KIR63392.1 - 0.089 12.4 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Cupin zinc_ribbon_10 PF10058.9 KIR63392.1 - 0.1 12.4 1.0 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Ribosomal_S27 PF01599.19 KIR63392.1 - 0.11 12.7 0.1 7.8 6.7 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein S27a Rubredoxin_2 PF18073.1 KIR63392.1 - 0.16 11.7 4.7 0.3 10.9 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 KIR63392.1 - 1.1 8.9 4.8 0.94 9.1 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 KIR63392.1 - 1.9 8.6 5.4 5.2 7.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Amidase PF01425.21 KIR63393.1 - 1e-93 314.8 0.3 5.4e-93 312.4 0.3 1.8 1 1 0 1 1 1 1 Amidase DUF5130 PF17174.4 KIR63395.1 - 7.7e-27 94.2 0.0 9e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) TPM_phosphatase PF04536.14 KIR63395.1 - 6.7e-08 32.7 0.0 7.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 TPM domain Peptidase_M1 PF01433.20 KIR63396.1 - 6e-58 196.0 2.0 1.1e-57 195.1 2.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KIR63396.1 - 1.7e-52 178.9 6.7 2.7e-52 178.3 6.7 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KIR63396.1 - 2e-18 67.2 0.0 4.7e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain WLM PF08325.10 KIR63396.1 - 0.096 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 WLM domain DSBA PF01323.20 KIR63397.1 - 2.5e-06 27.4 0.4 8.4e-05 22.4 0.4 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain UBA PF00627.31 KIR63397.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 UBA/TS-N domain DUF1015 PF06245.11 KIR63398.1 - 3.1e-49 167.9 0.0 7.5e-49 166.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1015) MazE_antitoxin PF04014.18 KIR63398.1 - 0.072 13.0 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin LacAB_rpiB PF02502.18 KIR63399.1 - 2.9e-44 150.4 0.0 3.2e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Acetyltransf_9 PF13527.7 KIR63401.1 - 6.9e-31 107.0 0.0 1.2e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 KIR63401.1 - 1.5e-21 77.4 4.8 1.8e-21 77.1 3.4 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 KIR63401.1 - 9.5e-19 67.7 0.0 2.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_1 PF00583.25 KIR63401.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIR63401.1 - 0.0005 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIR63401.1 - 0.0037 17.7 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR63401.1 - 0.046 13.7 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4282 PF14110.6 KIR63402.1 - 2.2 9.1 4.5 1 10.2 1.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) AMP-binding PF00501.28 KIR63403.1 - 3.9e-88 295.9 0.0 4.9e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR63403.1 - 3.7e-25 88.7 3.5 7.8e-25 87.7 3.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KIR63403.1 - 3.1e-22 78.3 0.1 8.4e-22 76.9 0.0 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HSP70 PF00012.20 KIR63404.1 - 3.6e-23 81.6 0.0 4.2e-22 78.1 0.0 2.1 1 1 1 2 2 2 1 Hsp70 protein PQQ_2 PF13360.6 KIR63404.1 - 4.6e-08 32.9 7.0 4.6e-08 32.9 7.0 2.6 1 1 2 3 3 3 2 PQQ-like domain PQQ PF01011.21 KIR63404.1 - 0.00012 21.8 0.1 0.16 11.9 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat MreB_Mbl PF06723.13 KIR63404.1 - 0.002 17.0 1.4 0.2 10.4 0.0 3.0 2 1 0 2 2 2 2 MreB/Mbl protein Pirin PF02678.16 KIR63405.1 - 1.2e-31 108.8 1.2 1.9e-31 108.2 1.2 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 KIR63405.1 - 9.8e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain YceI PF04264.13 KIR63406.1 - 5.8e-48 163.2 1.6 6.6e-48 163.0 1.6 1.0 1 0 0 1 1 1 1 YceI-like domain MarR_2 PF12802.7 KIR63407.1 - 1.8e-10 40.5 1.8 2.3e-10 40.2 0.3 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KIR63407.1 - 1.4e-06 28.7 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 KIR63407.1 - 4.5e-05 23.3 0.0 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 KIR63407.1 - 0.0064 16.5 4.3 0.054 13.6 0.1 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_5 PF01022.20 KIR63407.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HxlR PF01638.17 KIR63407.1 - 0.047 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF4194 PF13835.6 KIR63407.1 - 0.056 13.2 0.8 9.7 5.9 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4194) DUF732 PF05305.14 KIR63408.1 - 0.0096 16.3 0.8 0.058 13.8 0.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF732) RicinB_lectin_2 PF14200.6 KIR63409.1 - 3.7e-37 126.9 19.3 2.3e-23 82.7 3.5 3.9 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR63409.1 - 2.6e-23 82.6 5.1 5.9e-23 81.5 5.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_43 PF04616.14 KIR63409.1 - 1.4e-18 67.3 6.2 1.4e-18 67.3 6.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CDtoxinA PF03498.14 KIR63409.1 - 0.0014 18.2 0.2 0.0025 17.4 0.2 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain UPF0556 PF10572.9 KIR63409.1 - 0.56 9.7 6.3 3.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0556 AAA_33 PF13671.6 KIR63410.1 - 2.6e-10 40.6 0.0 4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KIR63410.1 - 9.2e-05 22.4 0.5 0.00011 22.1 0.5 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KIR63410.1 - 0.00047 20.7 0.3 0.0013 19.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIR63410.1 - 0.001 19.5 0.2 0.0022 18.4 0.2 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIR63410.1 - 0.0083 16.4 0.3 0.019 15.2 0.3 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIR63410.1 - 0.0091 16.4 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR63410.1 - 0.0093 16.2 0.3 0.018 15.3 0.3 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KIR63410.1 - 0.015 15.4 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate kinase Cytidylate_kin2 PF13189.6 KIR63410.1 - 0.059 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Zeta_toxin PF06414.12 KIR63410.1 - 0.09 12.0 0.1 0.19 10.9 0.1 1.5 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 KIR63410.1 - 0.21 11.3 0.3 0.3 10.8 0.3 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family HTH_31 PF13560.6 KIR63411.1 - 3.6e-12 46.5 0.6 3.6e-12 46.5 0.6 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR63411.1 - 0.0025 17.8 0.0 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR63411.1 - 0.019 15.4 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TPR_8 PF13181.6 KIR63411.1 - 0.092 13.0 0.0 8.7 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_3 PF01381.22 KIR63411.1 - 0.14 12.3 0.1 0.39 10.8 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix TPR_12 PF13424.6 KIR63411.1 - 1.2 9.4 11.4 0.95 9.8 0.2 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat GntR PF00392.21 KIR63413.1 - 2.3e-20 72.0 0.0 2.3e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family UTRA PF07702.13 KIR63413.1 - 6.3e-19 68.2 0.0 8e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 UTRA domain Rrf2 PF02082.20 KIR63413.1 - 0.0043 17.4 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator HTH_41 PF14502.6 KIR63413.1 - 0.0071 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR63413.1 - 0.013 15.3 0.1 0.1 12.5 0.0 2.4 3 0 0 3 3 3 0 MarR family HTH_11 PF08279.12 KIR63413.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 KIR63413.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR63413.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KIR63413.1 - 0.14 11.7 0.1 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR63413.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 MarR family Leu_leader PF08054.11 KIR63413.1 - 0.48 10.1 2.8 0.5 10.0 0.6 2.0 2 0 0 2 2 2 0 Leucine operon leader peptide FtsK_SpoIIIE PF01580.18 KIR63415.1 - 1.1e-15 57.7 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KIR63415.1 - 0.0017 17.3 0.1 0.036 13.0 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KIR63415.1 - 0.0034 17.8 2.4 0.095 13.1 0.7 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF853 PF05872.12 KIR63415.1 - 0.015 13.9 0.4 0.081 11.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_29 PF13555.6 KIR63415.1 - 0.031 14.0 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KIR63415.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KIR63415.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIR63415.1 - 0.26 10.4 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2637 PF10935.8 KIR63416.1 - 0.00082 19.3 7.8 0.0011 18.8 7.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2637) HTH_17 PF12728.7 KIR63417.1 - 2.6e-09 37.1 0.1 3.7e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Exc PF07825.11 KIR63417.1 - 0.0022 17.9 0.2 0.0026 17.7 0.2 1.1 1 0 0 1 1 1 1 Excisionase-like protein DUF483 PF04467.12 KIR63417.1 - 0.0044 17.0 0.0 0.0046 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF483) Trigger_N PF05697.13 KIR63418.1 - 5.6e-39 133.7 1.0 5.6e-39 133.7 1.0 2.5 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 KIR63418.1 - 5.7e-32 111.0 4.6 5.7e-32 111.0 4.6 2.2 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 KIR63418.1 - 5.9e-07 29.7 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BAR PF03114.18 KIR63418.1 - 0.018 14.7 0.8 0.031 13.9 0.8 1.3 1 0 0 1 1 1 0 BAR domain DUF4201 PF13870.6 KIR63418.1 - 0.029 14.1 2.0 0.13 12.0 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) XhlA PF10779.9 KIR63418.1 - 0.034 14.3 0.3 0.15 12.3 0.3 2.1 1 0 0 1 1 1 0 Haemolysin XhlA Ub-Mut7C PF14451.6 KIR63418.1 - 0.14 12.0 1.0 1.5 8.7 0.2 3.1 2 1 1 3 3 3 0 Mut7-C ubiquitin SurA_N_3 PF13624.6 KIR63418.1 - 0.25 11.1 7.1 0.33 10.7 1.3 3.2 3 1 1 4 4 4 0 SurA N-terminal domain Corona_S2 PF01601.16 KIR63418.1 - 0.32 9.4 0.2 0.48 8.9 0.2 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1664 PF07889.12 KIR63418.1 - 0.36 10.9 5.5 2.7 8.0 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 KIR63418.1 - 1 9.5 10.4 6.5 6.9 5.9 2.5 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Snapin_Pallidin PF14712.6 KIR63418.1 - 1.3 9.5 3.6 2.4 8.7 0.1 2.7 3 0 0 3 3 2 0 Snapin/Pallidin cwf21 PF08312.12 KIR63418.1 - 1.3 9.2 10.6 0.55 10.4 1.8 3.6 2 1 0 2 2 2 0 cwf21 domain Phage_TAC_4 PF08748.11 KIR63418.1 - 5.1 7.4 6.2 2.9 8.2 2.5 2.5 2 1 0 2 2 2 0 Phage tail assembly chaperone HIP1_clath_bdg PF16515.5 KIR63418.1 - 9.8 6.9 10.5 0.55 10.9 1.6 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CLP_protease PF00574.23 KIR63419.1 - 3.8e-78 261.5 0.1 4.6e-78 261.3 0.1 1.0 1 0 0 1 1 1 1 Clp protease GTP1_OBG PF01018.22 KIR63419.1 - 0.035 13.7 0.0 0.076 12.6 0.0 1.6 1 1 0 1 1 1 0 GTP1/OBG Peptidase_S49 PF01343.18 KIR63419.1 - 0.12 12.3 1.1 0.19 11.7 0.2 1.7 2 0 0 2 2 2 0 Peptidase family S49 CLP_protease PF00574.23 KIR63420.1 - 2.6e-75 252.3 0.1 3.1e-75 252.1 0.1 1.0 1 0 0 1 1 1 1 Clp protease DDR_swiveling PF18427.1 KIR63420.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain AAA_2 PF07724.14 KIR63421.1 - 5.7e-50 169.8 0.0 9.2e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 KIR63421.1 - 7.5e-21 73.7 6.0 2e-20 72.4 6.0 1.8 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 KIR63421.1 - 1.7e-16 60.8 0.0 4.2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIR63421.1 - 4.6e-16 58.6 0.1 1.4e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIR63421.1 - 2e-07 31.1 0.0 1.2e-06 28.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIR63421.1 - 1.9e-06 27.4 1.0 0.0088 15.4 0.2 3.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KIR63421.1 - 6.4e-06 26.0 0.7 0.00011 22.0 0.7 2.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIR63421.1 - 1.3e-05 25.5 0.2 0.00013 22.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain MCM PF00493.23 KIR63421.1 - 5.2e-05 22.4 0.0 9.9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 KIR63421.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KIR63421.1 - 0.00039 21.0 0.0 0.00095 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR63421.1 - 0.0013 19.1 0.1 0.011 16.2 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 KIR63421.1 - 0.0014 18.4 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TsaE PF02367.17 KIR63421.1 - 0.0046 16.9 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KIR63421.1 - 0.0061 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KIR63421.1 - 0.0075 15.5 0.6 0.074 12.2 0.6 2.2 1 1 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KIR63421.1 - 0.011 16.2 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KIR63421.1 - 0.013 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KIR63421.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KIR63421.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KIR63421.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KIR63421.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIR63421.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KIR63421.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 KIR63421.1 - 0.04 14.1 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KIR63421.1 - 0.053 13.6 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 KIR63421.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_28 PF13521.6 KIR63421.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIR63421.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KIR63421.1 - 0.084 13.2 0.9 0.61 10.4 0.1 2.6 2 1 1 3 3 3 0 AAA domain SKI PF01202.22 KIR63421.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase NTPase_1 PF03266.15 KIR63421.1 - 0.18 11.7 0.3 17 5.2 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_25 PF13481.6 KIR63421.1 - 0.23 11.0 0.8 2.6 7.6 0.1 2.2 1 1 0 2 2 2 0 AAA domain CN_hydrolase PF00795.22 KIR63422.1 - 7.3e-62 209.1 0.0 8.1e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AI-2E_transport PF01594.16 KIR63423.1 - 0.0009 18.5 4.3 0.00099 18.4 4.3 1.0 1 0 0 1 1 1 1 AI-2E family transporter RseC_MucC PF04246.12 KIR63423.1 - 0.29 11.1 1.9 0.32 10.9 1.9 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.6 KIR63423.1 - 2.5 7.7 7.0 2.7 7.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TauE PF01925.19 KIR63424.1 - 1.5e-05 24.8 11.8 3.2e-05 23.7 11.5 1.6 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DUF1453 PF07301.11 KIR63424.1 - 0.26 11.3 2.3 0.43 10.6 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1453) EamA PF00892.20 KIR63425.1 - 5.8e-41 139.9 23.6 3.5e-21 75.8 7.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KIR63425.1 - 0.0016 17.9 4.5 0.072 12.4 0.6 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family RseC_MucC PF04246.12 KIR63425.1 - 0.033 14.1 1.4 0.033 14.1 1.4 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC CRT-like PF08627.10 KIR63425.1 - 0.33 9.8 1.9 0.27 10.2 0.2 1.6 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DUF2517 PF10725.9 KIR63425.1 - 0.52 10.1 2.6 2 8.2 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2517) Glyco_hydro81C PF17652.1 KIR63426.1 - 1.5e-61 208.6 0.7 2.3e-61 208.0 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain DivIVA PF05103.13 KIR63428.1 - 3.4e-05 23.9 0.0 4.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 DivIVA protein MFS_1 PF07690.16 KIR63429.1 - 2e-48 165.1 60.7 2e-48 165.1 60.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR63429.1 - 5.3e-07 28.8 22.6 9.7e-07 28.0 6.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KIR63429.1 - 2e-06 26.5 6.2 2e-06 26.5 6.2 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 KIR63429.1 - 5e-05 22.3 15.4 0.0075 15.2 7.8 2.5 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 KIR63429.1 - 0.7 8.1 5.8 5.8 5.1 0.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2583 PF10762.9 KIR63429.1 - 5.5 7.5 10.1 2.6 8.5 0.8 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) LTD PF00932.19 KIR63431.1 - 6.2e-27 94.2 3.1 7.6e-27 93.9 3.1 1.1 1 0 0 1 1 1 1 Lamin Tail Domain PPC PF04151.15 KIR63431.1 - 0.15 13.1 4.3 1.3 10.2 0.3 2.3 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain HTH_17 PF12728.7 KIR63432.1 - 2.6e-06 27.5 0.1 3.1e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain DUF218 PF02698.17 KIR63433.1 - 2.3e-22 79.4 0.0 2.9e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain YjgF_endoribonc PF14588.6 KIR63434.1 - 8.4e-28 97.4 0.3 9.3e-28 97.2 0.3 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 KIR63434.1 - 1.3e-23 83.3 0.1 1.6e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP PGA_cap PF09587.10 KIR63435.1 - 2.3e-48 164.9 0.0 6.7e-48 163.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Peptidase_M41 PF01434.18 KIR63436.1 - 7.1e-70 234.7 0.3 1.3e-69 233.9 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIR63436.1 - 1.5e-44 151.6 0.0 2.8e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIR63436.1 - 9.7e-15 54.1 0.2 2.4e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KIR63436.1 - 1.3e-06 28.7 0.1 9.8e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 FtsH Extracellular TIP49 PF06068.13 KIR63436.1 - 0.00018 20.9 0.4 0.00043 19.6 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 KIR63436.1 - 0.00023 21.0 0.0 0.00063 19.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIR63436.1 - 0.00044 20.7 0.1 0.0013 19.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIR63436.1 - 0.00055 19.9 0.1 0.0062 16.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIR63436.1 - 0.00096 19.4 0.0 0.032 14.5 0.0 2.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIR63436.1 - 0.0058 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KIR63436.1 - 0.0076 15.8 0.4 1.3 8.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR63436.1 - 0.012 15.8 0.0 0.043 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR63436.1 - 0.025 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KIR63436.1 - 0.037 14.0 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KIR63436.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KIR63436.1 - 0.11 12.7 0.1 0.52 10.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KIR63436.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KIR63436.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIR63436.1 - 0.13 11.7 0.2 0.34 10.3 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KIR63436.1 - 0.33 11.3 1.3 6.8 7.0 0.3 2.7 2 0 0 2 2 2 0 AAA domain DUF3180 PF11377.8 KIR63437.1 - 1.9e-43 147.9 19.7 2.2e-43 147.6 19.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) DUF4231 PF14015.6 KIR63437.1 - 1.7 9.1 6.4 0.18 12.3 0.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) BPD_transp_1 PF00528.22 KIR63438.1 - 9.5e-20 71.1 14.6 1.3e-19 70.7 14.5 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component HTH_AsnC-type PF13404.6 KIR63438.1 - 0.11 12.3 1.0 16 5.4 0.2 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HhH-GPD PF00730.25 KIR63439.1 - 1.4e-13 51.2 0.0 2.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIR63439.1 - 3e-09 36.3 0.4 1.7e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KIR63439.1 - 3.3e-05 24.1 5.7 5.9e-05 23.3 5.7 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_8 PF14716.6 KIR63439.1 - 0.19 12.1 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Antimicrobial_7 PF08102.11 KIR63440.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Scorpion antimicrobial peptide DisA-linker PF10635.9 KIR63441.1 - 1.3e-49 167.7 0.9 1.9e-49 167.1 0.9 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller linker region DisA_N PF02457.16 KIR63441.1 - 1e-25 89.7 0.0 1.6e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding HHH_2 PF12826.7 KIR63441.1 - 2.3e-07 30.8 1.6 5.8e-06 26.3 0.0 3.0 3 1 0 3 3 3 1 Helix-hairpin-helix motif HHH PF00633.23 KIR63441.1 - 0.0007 19.3 0.1 0.0022 17.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KIR63441.1 - 0.002 18.7 0.0 0.006 17.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain PCuAC PF04314.13 KIR63442.1 - 2e-05 24.3 0.0 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Copper chaperone PCu(A)C SPX PF03105.19 KIR63442.1 - 0.48 10.3 1.5 0.45 10.4 1.5 1.1 1 0 0 1 1 1 0 SPX domain Chal_sti_synt_C PF02797.15 KIR63443.1 - 1e-20 74.3 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 KIR63443.1 - 3.7e-16 59.2 0.1 5.4e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 KIR63443.1 - 1.8e-11 44.1 0.0 5.5e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 KIR63443.1 - 3.9e-07 29.7 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KIR63443.1 - 0.0052 16.6 0.3 0.015 15.2 0.2 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III T7SS_ESX1_EccB PF05108.13 KIR63443.1 - 0.012 14.4 0.1 0.021 13.5 0.0 1.4 2 0 0 2 2 2 0 Type VII secretion system ESX-1, transport TM domain B DUF397 PF04149.12 KIR63444.1 - 2.8e-21 75.3 0.8 3.2e-21 75.1 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) PQQ_2 PF13360.6 KIR63445.1 - 7.7e-12 45.3 11.4 1.7e-08 34.4 2.1 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 KIR63445.1 - 5.8e-06 26.0 3.6 3.3 7.8 0.0 6.0 6 0 0 6 6 6 2 PQQ enzyme repeat Laminin_G_3 PF13385.6 KIR63446.1 - 2.8e-28 99.0 6.4 2.8e-28 99.0 6.4 4.5 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily CarboxypepD_reg PF13620.6 KIR63446.1 - 8.7e-28 96.4 64.0 2.7e-10 40.4 3.2 8.0 8 1 1 9 9 9 4 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KIR63446.1 - 4.9e-25 87.4 11.0 8.7e-07 28.9 0.3 5.1 4 0 0 4 4 4 4 CarboxypepD_reg-like domain SdrD_B PF17210.3 KIR63446.1 - 8.1e-09 35.7 16.9 0.0036 17.5 0.1 5.2 5 0 0 5 5 5 3 SdrD B-like domain DUF2012 PF09430.10 KIR63446.1 - 3.6e-05 23.9 0.0 0.67 10.1 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF2012) SpaA PF17802.1 KIR63446.1 - 0.032 14.6 20.5 0.28 11.5 0.5 6.1 4 1 0 4 4 4 0 Prealbumin-like fold domain Dioxygenase_C PF00775.21 KIR63446.1 - 0.075 12.5 1.1 11 5.4 0.1 3.3 3 1 0 3 3 3 0 Dioxygenase CooC_C PF15976.5 KIR63446.1 - 0.11 12.6 0.2 18 5.4 0.0 3.5 3 0 0 3 3 3 0 CS1-pili formation C-terminal phage_tail_N PF08400.10 KIR63446.1 - 0.16 11.9 1.7 0.97 9.4 0.1 2.8 2 0 0 2 2 2 0 Prophage tail fibre N-terminal Phage_Mu_Gp45 PF06890.12 KIR63446.1 - 0.26 11.1 5.4 0.27 11.0 0.4 3.3 3 0 0 3 3 3 0 Bacteriophage Mu Gp45 protein Putative_PNPOx PF01243.20 KIR63447.1 - 6.7e-15 55.0 0.0 9.3e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KIR63447.1 - 0.00085 19.3 0.0 0.001 19.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F420H2_quin_red PF04075.14 KIR63447.1 - 0.057 13.6 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase DUF4338 PF14236.6 KIR63447.1 - 0.11 11.8 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) DUF3821 PF12863.7 KIR63447.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Peptidase_S8 PF00082.22 KIR63448.1 - 2.1e-35 122.4 0.3 5.4e-35 121.1 0.0 1.8 2 0 0 2 2 2 1 Subtilase family MTES_1575 PF18741.1 KIR63449.1 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 KIR63449.1 - 0.00011 22.0 0.2 0.00036 20.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF559) HTH_IclR PF09339.10 KIR63450.1 - 9.1e-13 47.8 0.6 9.1e-13 47.8 0.6 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR63450.1 - 2.2e-07 30.6 0.9 5.8e-07 29.3 0.9 1.6 1 0 0 1 1 1 1 MarR family HTH_17 PF12728.7 KIR63450.1 - 0.00028 21.0 0.0 0.00062 19.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 KIR63450.1 - 0.00029 20.7 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 KIR63450.1 - 0.00049 19.8 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KIR63450.1 - 0.0015 18.5 0.1 0.0037 17.3 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KIR63450.1 - 0.0025 17.9 0.1 0.0067 16.5 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR63450.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KIR63450.1 - 0.016 15.2 1.3 0.024 14.7 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 KIR63450.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_8 PF02954.19 KIR63450.1 - 0.05 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family IclR PF01614.18 KIR63450.1 - 0.058 13.2 0.8 0.94 9.3 0.1 2.4 1 1 1 2 2 2 0 Bacterial transcriptional regulator His_Phos_1 PF00300.22 KIR63451.1 - 4.2e-25 88.6 1.5 6.9e-24 84.6 1.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ECH_1 PF00378.20 KIR63452.1 - 2e-43 148.5 0.1 2.4e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR63452.1 - 4.8e-25 88.8 0.0 5.8e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TrkA_N PF02254.18 KIR63453.1 - 4e-31 107.7 0.0 2e-21 76.4 0.2 2.6 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 KIR63453.1 - 1.4e-07 31.3 0.1 5.6e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 TrkA-C domain 2-Hacid_dh_C PF02826.19 KIR63453.1 - 0.00013 21.4 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIR63453.1 - 0.00026 21.4 0.0 0.037 14.5 0.1 3.0 3 1 0 3 3 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KIR63453.1 - 0.0053 16.3 0.3 0.011 15.3 0.3 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 KIR63453.1 - 0.02 14.2 0.2 0.036 13.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIR63453.1 - 0.027 13.7 1.0 0.052 12.8 1.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 KIR63453.1 - 0.034 15.0 0.0 0.09 13.6 0.0 1.8 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.27 KIR63453.1 - 0.054 14.1 0.2 0.23 12.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ni_hydr_CYTB PF01292.20 KIR63453.1 - 0.06 12.9 0.6 0.1 12.2 0.6 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 ApbA PF02558.16 KIR63453.1 - 0.079 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 KIR63453.1 - 0.081 13.4 0.9 0.16 12.4 0.1 2.0 2 0 0 2 2 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KIR63453.1 - 0.13 12.1 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4032 PF13224.6 KIR63454.1 - 1.3e-62 210.4 2.9 2e-62 209.9 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) Kdo PF06293.14 KIR63454.1 - 3.7e-10 39.5 0.1 6.6e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3258 PF11646.8 KIR63454.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF3258 ATP_bind_1 PF03029.17 KIR63455.1 - 5e-21 75.6 0.5 1.3e-19 70.9 0.5 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KIR63455.1 - 0.0077 15.8 0.2 0.029 14.0 0.2 1.9 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KIR63455.1 - 0.0088 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NTPase_1 PF03266.15 KIR63455.1 - 0.078 12.9 0.2 1.9 8.4 0.7 2.1 2 0 0 2 2 2 0 NTPase Roc PF08477.13 KIR63455.1 - 0.086 13.1 0.1 0.63 10.3 0.1 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DBI_PRT PF02277.17 KIR63455.1 - 0.12 11.5 0.7 0.18 11.0 0.7 1.1 1 0 0 1 1 1 0 Phosphoribosyltransferase AAA_24 PF13479.6 KIR63455.1 - 0.32 10.7 1.4 0.37 10.5 0.4 1.5 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KIR63455.1 - 1.5 9.4 2.9 1.5 9.3 0.7 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIR63455.1 - 2.2 7.3 4.4 0.59 9.1 1.3 1.6 1 1 1 2 2 2 0 Type II/IV secretion system protein DUF742 PF05331.11 KIR63456.1 - 1.2e-24 86.3 0.1 1.4e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Peptidase_S8 PF00082.22 KIR63458.1 - 1.6e-36 126.1 0.0 2.2e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF2079 PF09852.9 KIR63458.1 - 0.27 10.0 4.8 0.59 8.9 4.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF2076 PF09849.9 KIR63458.1 - 0.66 10.0 5.0 1.5 8.8 5.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HD PF01966.22 KIR63459.1 - 0.062 13.5 0.3 0.1 12.9 0.3 1.5 1 0 0 1 1 1 0 HD domain Aminotran_5 PF00266.19 KIR63460.1 - 2.2e-72 244.1 0.0 1.6e-71 241.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIR63460.1 - 0.0057 15.9 0.0 0.06 12.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II PrsW-protease PF13367.6 KIR63461.1 - 7.8e-47 159.3 13.8 7.8e-47 159.3 13.8 1.8 2 0 0 2 2 2 1 PrsW family intramembrane metalloprotease PPK2 PF03976.14 KIR63462.1 - 4.1e-63 212.9 0.0 5.6e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) Glyco_tranf_2_3 PF13641.6 KIR63463.1 - 2.2e-18 67.0 1.9 3e-18 66.5 1.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIR63463.1 - 3.5e-15 56.2 0.1 5.9e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KIR63463.1 - 6.7e-13 49.0 5.9 9.6e-13 48.5 5.9 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KIR63463.1 - 1.2e-07 31.3 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 SIS PF01380.22 KIR63463.1 - 0.13 12.1 0.2 0.49 10.3 0.1 1.8 1 1 1 2 2 2 0 SIS domain Gram_pos_anchor PF00746.21 KIR63464.1 - 0.044 13.7 1.1 0.046 13.7 1.1 1.1 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Aminotran_4 PF01063.19 KIR63465.1 - 4.4e-45 154.3 0.0 5.1e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV adh_short PF00106.25 KIR63467.1 - 8.9e-50 168.9 3.1 1.2e-49 168.5 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR63467.1 - 1.3e-34 119.8 5.8 1.7e-34 119.4 5.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR63467.1 - 2.3e-14 53.7 2.4 3e-14 53.3 2.4 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIR63467.1 - 5.8e-05 23.1 5.7 5.8e-05 23.1 5.7 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIR63467.1 - 0.00017 21.2 1.8 0.00036 20.1 0.5 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 KIR63467.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda LytR_C PF13399.6 KIR63467.1 - 2 9.4 6.9 5.7 8.0 4.0 2.7 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator PhoU PF01895.19 KIR63468.1 - 1.3e-31 108.8 8.8 7.8e-19 67.9 6.6 2.3 2 0 0 2 2 2 2 PhoU domain ABC_ATPase PF09818.9 KIR63468.1 - 0.056 12.2 0.8 0.067 12.0 0.8 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SpmSyn_N PF17950.1 KIR63468.1 - 0.074 13.2 0.1 0.24 11.6 0.1 1.9 1 1 1 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal Peptidase_M75 PF09375.10 KIR63468.1 - 0.14 11.6 3.3 0.56 9.6 3.3 1.8 1 1 0 1 1 1 0 Imelysin AP_endonuc_2 PF01261.24 KIR63469.1 - 5.7e-17 61.9 1.4 1.3e-16 60.6 0.4 2.0 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel GDPD PF03009.17 KIR63469.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family HTH_17 PF12728.7 KIR63471.1 - 1.8e-13 50.4 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR63471.1 - 0.001 18.8 0.1 0.0042 16.9 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KIR63471.1 - 0.0014 18.1 0.1 0.082 12.4 0.1 2.1 1 1 1 2 2 2 1 Sigma-70, region 4 AbiEi_4 PF13338.6 KIR63471.1 - 0.0033 17.6 0.1 0.0049 17.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin HTH_22 PF13309.6 KIR63471.1 - 0.0066 16.5 0.4 0.037 14.1 0.2 1.9 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 KIR63471.1 - 0.039 13.8 0.1 3.5 7.6 0.1 2.0 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KIR63471.1 - 0.053 13.6 0.1 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 KIR63471.1 - 0.06 12.8 0.5 0.14 11.6 0.3 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 KIR63471.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 KIR63471.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain Epimerase PF01370.21 KIR63472.1 - 8.2e-20 71.3 0.0 1.4e-19 70.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR63472.1 - 5.6e-07 29.3 0.0 3.4e-06 26.7 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIR63472.1 - 0.0022 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIR63472.1 - 0.0036 16.3 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIR63472.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein Acyltransferase PF01553.21 KIR63473.1 - 4.7e-17 61.9 0.0 7.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KIR63473.1 - 0.00026 20.0 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Optomotor-blind PF11078.8 KIR63473.1 - 0.12 12.9 0.3 0.12 12.9 0.3 1.9 2 1 0 2 2 2 0 Optomotor-blind protein N-terminal region Response_reg PF00072.24 KIR63474.1 - 9.7e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR63474.1 - 2.7e-13 49.3 0.0 4.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR63474.1 - 2.7e-06 27.0 0.2 9.1e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR63474.1 - 0.0026 17.2 0.1 0.009 15.5 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KIR63474.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KIR63475.1 - 3.3e-11 43.3 2.8 3.3e-11 43.3 2.8 2.3 3 1 1 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR63475.1 - 4.7e-09 36.2 0.0 6.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 KIR63475.1 - 0.0023 17.7 0.2 0.0088 15.8 0.2 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KIR63475.1 - 0.0028 17.4 0.4 0.0051 16.5 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR63475.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR63475.1 - 0.0053 16.8 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR63475.1 - 0.0083 15.9 0.3 0.02 14.7 0.3 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_25 PF13413.6 KIR63475.1 - 0.015 15.1 0.2 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 KIR63475.1 - 0.027 14.4 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 KIR63475.1 - 0.039 13.4 0.2 0.071 12.5 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KIR63475.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR63475.1 - 0.071 12.9 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MqsA_antitoxin PF15731.5 KIR63475.1 - 0.19 11.8 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA AA_permease_2 PF13520.6 KIR63476.1 - 7.2e-54 183.2 34.6 8.9e-54 182.9 34.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIR63476.1 - 6.5e-42 143.7 33.3 7.8e-42 143.5 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 KIR63476.1 - 1.2e-17 63.7 5.3 1.2e-17 63.7 5.3 4.3 5 0 0 5 5 5 1 C-terminus of AA_permease tRNA_NucTransf2 PF09249.11 KIR63476.1 - 0.081 13.2 0.1 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain O-antigen_lig PF13425.6 KIR63476.1 - 7.6 5.2 7.0 0.88 8.3 0.2 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Peripla_BP_3 PF13377.6 KIR63477.1 - 5.9e-38 130.8 2.4 5.9e-38 130.8 2.4 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR63477.1 - 1.5e-26 93.5 0.0 1.9e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR63477.1 - 8.3e-18 63.9 0.5 8.3e-18 63.9 0.5 2.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR63477.1 - 2.5e-10 40.4 0.0 5.3e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 KIR63477.1 - 0.00053 20.0 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR63477.1 - 0.0013 19.1 1.1 0.0075 16.6 0.1 2.9 2 1 0 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR63477.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KIR63477.1 - 0.06 13.2 0.1 0.22 11.4 0.1 2.1 1 0 0 1 1 1 0 Homeodomain-like domain MerR PF00376.23 KIR63477.1 - 0.079 12.7 0.1 2.2 8.1 0.1 3.0 3 0 0 3 3 3 0 MerR family regulatory protein DUF1835 PF08874.10 KIR63477.1 - 0.2 11.8 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) HOOK PF05622.12 KIR63478.1 - 0.34 9.0 11.0 0.086 11.0 0.8 2.0 1 1 0 2 2 2 0 HOOK protein Selenoprotein_S PF06936.11 KIR63478.1 - 0.65 9.8 3.9 20 4.9 0.0 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF4140 PF13600.6 KIR63478.1 - 3.2 8.2 7.3 28 5.2 2.6 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.6 KIR63478.1 - 8.8 6.8 12.6 5.1 7.5 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Abhydrolase_1 PF00561.20 KIR63479.1 - 5e-24 85.3 0.0 2.5e-17 63.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR63479.1 - 1.8e-19 71.2 10.8 2.6e-19 70.7 10.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR63479.1 - 1.1e-16 60.9 0.1 2.6e-16 59.6 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIR63479.1 - 0.0001 22.5 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain IFRD PF05004.13 KIR63479.1 - 0.00015 21.0 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) AXE1 PF05448.12 KIR63479.1 - 0.0014 17.4 0.0 0.004 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 KIR63479.1 - 0.0057 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein PGAP1 PF07819.13 KIR63479.1 - 0.014 15.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.12 KIR63479.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.9 KIR63479.1 - 0.22 10.6 0.0 0.55 9.3 0.0 1.6 2 0 0 2 2 2 0 Abhydrolase domain containing 18 ThiF PF00899.21 KIR63480.1 - 5.6e-65 219.1 0.0 7.7e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KIR63480.1 - 2.4e-13 50.5 0.0 5.8e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 KIR63480.1 - 0.03 14.6 0.6 0.5 10.6 0.4 2.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KIR63481.1 - 6.1e-74 248.1 0.8 7e-73 244.6 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 KIR63481.1 - 2e-13 50.2 0.0 3.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR63481.1 - 4.1e-06 26.8 0.2 1.7e-05 24.8 0.2 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KIR63481.1 - 0.0015 18.7 0.3 0.0054 16.9 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIR63481.1 - 0.0045 16.3 0.3 0.0045 16.3 0.3 1.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KIR63481.1 - 0.0075 15.0 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIR63481.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR63481.1 - 0.053 12.8 0.1 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR63481.1 - 0.091 12.3 3.2 0.075 12.6 1.0 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase NADHdh PF00146.21 KIR63482.1 - 3.7e-103 344.9 15.6 4.4e-103 344.7 15.6 1.0 1 0 0 1 1 1 1 NADH dehydrogenase SecE PF00584.20 KIR63484.1 - 3.4e-20 71.7 5.3 4.3e-20 71.4 5.3 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4190 PF13828.6 KIR63485.1 - 0.046 13.5 12.3 0.069 12.9 10.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) Beta-APP PF03494.13 KIR63485.1 - 0.29 11.0 2.1 0.63 9.9 2.1 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF2275 PF10039.9 KIR63485.1 - 0.57 10.3 2.1 0.74 9.9 2.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) MFS_MOT1 PF16983.5 KIR63485.1 - 0.67 10.4 9.7 1.3 9.5 9.7 1.6 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily DUF309 PF03745.14 KIR63485.1 - 1.3 8.8 3.7 1.6 8.4 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Phage_holin_3_6 PF07332.11 KIR63485.1 - 3.8 7.6 15.5 6.2 6.9 15.5 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4190 PF13828.6 KIR63486.1 - 1.3e-08 34.5 8.6 1.3e-08 34.5 8.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4190) Phage_holin_3_6 PF07332.11 KIR63486.1 - 0.0059 16.6 12.2 0.0059 16.6 12.2 2.0 1 1 1 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_7_1 PF16081.5 KIR63486.1 - 0.012 15.8 6.3 0.012 15.8 6.3 1.3 1 1 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Phage_holin_3_3 PF16083.5 KIR63486.1 - 1.6 8.9 17.8 1.9 8.7 2.6 2.3 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III ribosomal_L24 PF17136.4 KIR63487.1 - 5e-24 84.5 1.0 8.1e-24 83.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 KIR63487.1 - 2.3e-07 30.5 2.4 2.3e-07 30.5 2.4 2.3 3 0 0 3 3 3 1 KOW motif DUF4438 PF14505.6 KIR63487.1 - 0.033 13.2 0.8 0.039 12.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) eIF3g PF12353.8 KIR63487.1 - 0.12 12.8 0.9 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G GTP_EFTU_D2 PF03144.25 KIR63487.1 - 0.53 10.7 6.2 6.1 7.3 3.2 2.9 2 1 0 2 2 2 0 Elongation factor Tu domain 2 Ribosomal_L18p PF00861.22 KIR63488.1 - 1.1e-47 161.2 3.7 1.2e-47 161.0 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DNA_photolyase PF00875.18 KIR63488.1 - 0.092 12.8 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 DNA photolyase MTS PF05175.14 KIR63489.1 - 6.5e-26 90.9 0.0 7.6e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIR63489.1 - 3.3e-05 24.5 0.0 4.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR63489.1 - 0.00033 20.5 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR63489.1 - 0.00066 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR63489.1 - 0.00078 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIR63489.1 - 0.0022 18.0 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIR63489.1 - 0.0023 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KIR63489.1 - 0.0097 16.6 0.0 0.017 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIR63489.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 KIR63489.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain BPD_transp_1 PF00528.22 KIR63490.1 - 2.6e-24 86.0 17.4 4.4e-24 85.2 17.4 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Neurensin PF14927.6 KIR63490.1 - 0.83 9.4 4.8 0.13 11.9 0.3 2.0 3 0 0 3 3 3 0 Neurensin Rieske_2 PF13806.6 KIR63491.1 - 5.6e-36 122.6 0.0 6.5e-36 122.4 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KIR63491.1 - 0.00012 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.14 KIR63492.1 - 6.4e-48 163.5 0.9 9.9e-48 162.9 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KIR63492.1 - 1.5e-19 70.0 0.0 2.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 KIR63492.1 - 1.3e-17 63.9 5.2 4.5e-12 46.1 3.3 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 KIR63492.1 - 1.4e-16 60.8 0.2 3.2e-13 50.1 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 KIR63492.1 - 2.3e-10 40.2 0.0 5.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KIR63492.1 - 7e-08 32.3 0.0 1.9e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Trp_halogenase PF04820.14 KIR63492.1 - 0.00015 20.8 0.5 0.00038 19.4 0.0 1.7 1 1 1 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.24 KIR63492.1 - 0.0038 16.6 0.1 0.45 9.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 KIR63492.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIR63492.1 - 0.19 11.7 8.9 1.8 8.6 0.2 4.0 3 1 0 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.22 KIR63492.1 - 0.35 9.9 0.6 3.7 6.5 0.8 2.3 2 1 0 3 3 3 0 Glucose inhibited division protein A PemK_toxin PF02452.17 KIR63493.1 - 0.0022 18.4 0.1 0.0046 17.4 0.1 1.5 1 1 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system Abhydrolase_8 PF06259.12 KIR63494.1 - 6.7e-34 117.1 3.0 1.9e-33 115.6 3.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KIR63494.1 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR63494.1 - 0.056 13.1 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold WXG100 PF06013.12 KIR63494.1 - 0.098 12.9 0.9 0.34 11.2 0.9 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG TsaE PF02367.17 KIR63495.1 - 1.5e-28 99.3 0.0 1.8e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KIR63495.1 - 0.045 13.3 2.4 0.056 13.0 2.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR63495.1 - 0.066 13.0 0.2 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KIR63495.1 - 0.13 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KIR63495.1 - 0.15 11.2 0.3 0.21 10.8 0.3 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain cobW PF02492.19 KIR63495.1 - 0.2 11.2 0.6 0.36 10.4 0.6 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_1 PF00583.25 KIR63496.1 - 1.1e-15 57.9 0.1 1.3e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR63496.1 - 9.5e-13 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR63496.1 - 1.1e-11 44.9 0.0 1.5e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIR63496.1 - 2.1e-08 34.4 0.0 2.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR63496.1 - 2.4e-07 30.6 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIR63496.1 - 3.6e-06 27.7 0.1 4.4e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KIR63496.1 - 7e-05 22.6 0.5 0.00092 18.9 0.5 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KIR63496.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR63496.1 - 0.0024 17.5 0.1 0.003 17.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Toprim_3 PF13362.6 KIR63496.1 - 0.06 13.7 0.3 0.087 13.2 0.3 1.3 1 0 0 1 1 1 0 Toprim domain Acetyltransf_CG PF14542.6 KIR63496.1 - 0.074 13.2 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1707 PF08044.11 KIR63497.1 - 1.5e-20 73.0 8.9 1.5e-20 73.0 8.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1707) GDH_N PF12466.8 KIR63497.1 - 0.075 13.2 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Peripla_BP_4 PF13407.6 KIR63498.1 - 5.9e-55 186.6 15.2 7.3e-55 186.3 15.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 KIR63498.1 - 0.0028 18.0 0.0 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Cpn10 PF00166.21 KIR63499.1 - 1.1e-36 124.8 0.7 1.2e-36 124.6 0.7 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Whib PF02467.16 KIR63500.1 - 6.4e-22 77.9 3.2 8.5e-22 77.5 3.2 1.2 1 0 0 1 1 1 1 Transcription factor WhiB Peptidase_M1 PF01433.20 KIR63501.1 - 1.1e-27 97.0 0.3 2.4e-27 95.9 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIR63501.1 - 1.2e-16 61.5 0.0 2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KIR63501.1 - 0.43 11.0 2.7 19 5.6 2.7 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase adh_short PF00106.25 KIR63502.1 - 4.7e-41 140.4 3.9 1.9e-40 138.4 3.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR63502.1 - 1.9e-27 96.4 3.9 5.1e-27 94.9 3.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR63502.1 - 2.9e-07 30.6 1.5 4.3e-07 30.0 1.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR63502.1 - 0.00011 21.8 0.1 0.00013 21.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TSLP PF15216.6 KIR63502.1 - 0.27 11.5 0.0 0.42 10.9 0.0 1.2 1 0 0 1 1 1 0 Thymic stromal lymphopoietin NUDIX PF00293.28 KIR63503.1 - 1.8e-36 125.0 0.6 6.6e-19 68.3 0.1 2.1 2 0 0 2 2 2 2 NUDIX domain NUDIX_4 PF14815.6 KIR63503.1 - 9e-06 25.6 0.1 0.24 11.4 0.1 3.1 2 2 0 2 2 2 2 NUDIX domain NUDIX_2 PF13869.6 KIR63503.1 - 0.15 11.6 0.0 16 5.0 0.0 2.1 2 0 0 2 2 2 0 Nucleotide hydrolase CM_2 PF01817.21 KIR63504.1 - 8.9e-11 42.0 0.4 1.1e-10 41.7 0.4 1.1 1 0 0 1 1 1 1 Chorismate mutase type II GTP-bdg_M PF16360.5 KIR63504.1 - 0.55 10.9 3.7 0.81 10.3 0.5 2.1 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region PIG-P PF08510.12 KIR63505.1 - 0.25 11.3 0.8 0.42 10.5 0.8 1.3 1 0 0 1 1 1 0 PIG-P Pex14_N PF04695.13 KIR63505.1 - 0.39 11.4 1.1 2.2 8.9 0.1 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aminotran_1_2 PF00155.21 KIR63506.1 - 2e-42 145.7 0.0 2.7e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR63506.1 - 0.071 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Peptidase_S8 PF00082.22 KIR63507.1 - 8.4e-58 196.0 7.4 2.7e-57 194.3 7.4 1.8 1 1 0 1 1 1 1 Subtilase family Cohesin PF00963.18 KIR63507.1 - 0.066 13.5 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Cohesin domain Bac_luciferase PF00296.20 KIR63508.1 - 6.5e-82 275.5 25.3 7.6e-82 275.2 25.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase NUDIX PF00293.28 KIR63509.1 - 8.7e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIR63509.1 - 1.8e-10 41.4 0.3 3.5e-10 40.4 0.3 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIR63509.1 - 0.0015 18.1 0.0 0.0041 16.7 0.0 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Response_reg PF00072.24 KIR63510.1 - 1.9e-24 86.0 0.0 2.9e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR63510.1 - 2.9e-21 74.8 0.1 5.6e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR63510.1 - 6.8e-09 35.3 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR63510.1 - 8.5e-08 31.8 0.0 2.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KIR63510.1 - 8.4e-07 28.4 0.3 1.5e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 KIR63510.1 - 1.5e-06 28.2 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KIR63510.1 - 2.5e-06 27.1 0.6 6.2e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR63510.1 - 1.1e-05 25.4 0.0 3.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 KIR63510.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 KIR63510.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 KIR63510.1 - 0.00024 20.4 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 KIR63510.1 - 0.00033 20.5 0.1 0.0015 18.4 0.1 2.0 2 0 0 2 2 2 1 HTH domain HTH_40 PF14493.6 KIR63510.1 - 0.00037 20.9 0.1 0.00061 20.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 KIR63510.1 - 0.00042 20.1 0.3 0.0074 16.1 0.3 2.3 1 1 0 1 1 1 1 HTH DNA binding domain HTH_20 PF12840.7 KIR63510.1 - 0.00074 19.5 0.0 0.0028 17.7 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR63510.1 - 0.0033 17.4 0.1 0.0064 16.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix TadZ_N PF16968.5 KIR63510.1 - 0.0037 17.0 0.4 0.006 16.3 0.4 1.4 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal HTH_32 PF13565.6 KIR63510.1 - 0.0052 17.4 0.1 0.014 16.0 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 KIR63510.1 - 0.0072 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 KIR63510.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Mga PF08280.11 KIR63510.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain KORA PF16509.5 KIR63510.1 - 0.017 15.4 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_50 PF18024.1 KIR63510.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 KIR63510.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_26 PF13443.6 KIR63510.1 - 0.037 14.5 0.1 0.067 13.6 0.1 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF746 PF05344.11 KIR63510.1 - 0.038 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_17 PF12728.7 KIR63510.1 - 0.043 14.0 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KIR63510.1 - 0.043 13.7 0.6 0.27 11.2 0.1 2.4 2 0 0 2 2 2 0 MarR family DMAP1_like PF17024.5 KIR63510.1 - 0.049 13.8 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative DMAP1-like MLD PF11647.8 KIR63510.1 - 0.088 13.1 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 Membrane Localization Domain Sigma70_ECF PF07638.11 KIR63510.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor DUF134 PF02001.16 KIR63510.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 DUF2089 PF09862.9 KIR63510.1 - 0.22 11.6 0.0 0.5 10.4 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2089) RsgA_GTPase PF03193.16 KIR63511.1 - 5.9e-40 136.9 0.0 7.9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KIR63511.1 - 1.8e-06 28.0 0.0 4.6e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIR63511.1 - 4.7e-05 23.8 0.5 0.00014 22.3 0.1 1.9 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 KIR63511.1 - 0.0012 19.4 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KIR63511.1 - 0.0034 17.0 0.0 0.06 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR63511.1 - 0.0078 16.4 0.7 0.015 15.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KIR63511.1 - 0.01 16.0 0.0 0.045 14.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIR63511.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR63511.1 - 0.02 15.2 0.1 0.037 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KIR63511.1 - 0.03 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 KIR63511.1 - 0.031 14.2 0.6 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KIR63511.1 - 0.039 13.7 0.7 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KIR63511.1 - 0.04 13.4 0.2 1.4 8.4 0.1 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Ras PF00071.22 KIR63511.1 - 0.045 13.3 0.0 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 Ras family ATP-synt_ab PF00006.25 KIR63511.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 KIR63511.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KIR63511.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 KIR63511.1 - 0.18 11.8 0.3 3.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 KIR63511.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Septin EPSP_synthase PF00275.20 KIR63512.1 - 4.6e-100 335.2 0.0 5.2e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) CbiX PF01903.17 KIR63513.1 - 2.7e-28 98.4 0.1 1.9e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 CbiX PALP PF00291.25 KIR63513.1 - 0.0039 16.7 2.8 0.0039 16.7 2.8 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CbiK PF06180.11 KIR63513.1 - 0.011 15.1 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) Whib PF02467.16 KIR63514.1 - 6.3e-26 90.8 2.1 7.3e-26 90.5 2.1 1.1 1 0 0 1 1 1 1 Transcription factor WhiB Peptidase_S24 PF00717.23 KIR63515.1 - 7.1e-11 41.9 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like ADH_zinc_N_2 PF13602.6 KIR63516.1 - 5.7e-19 69.5 0.1 1.1e-18 68.6 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR63516.1 - 3.9e-17 62.5 4.6 6.6e-17 61.7 2.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR63516.1 - 9.5e-06 25.5 0.0 0.00082 19.2 0.0 2.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIR63516.1 - 0.0025 17.1 1.6 0.0037 16.6 1.6 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aminoglyc_resit PF10706.9 KIR63517.1 - 4.5e-06 26.5 0.1 6.5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Aminoglycoside-2''-adenylyltransferase PAF-AH_p_II PF03403.13 KIR63518.1 - 5.2e-08 31.8 0.1 2.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIR63518.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIR63518.1 - 1.9e-05 24.1 3.9 0.15 11.3 0.0 3.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR63518.1 - 0.00015 21.8 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KIR63518.1 - 0.0009 18.8 0.9 0.055 12.9 0.4 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KIR63518.1 - 0.003 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KIR63518.1 - 0.031 13.3 0.4 0.11 11.4 0.4 1.9 1 1 0 1 1 1 0 Chlorophyllase Acetyltransf_5 PF13444.6 KIR63519.1 - 6.4e-28 97.4 0.0 8.9e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Response_reg PF00072.24 KIR63520.1 - 4e-30 104.3 0.0 9.1e-30 103.1 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR63520.1 - 4.1e-28 97.3 0.2 1.2e-27 95.8 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 KIR63520.1 - 0.01 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ B12-binding PF02310.19 KIR63520.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain Aminotran_3 PF00202.21 KIR63521.1 - 2.3e-113 378.9 0.0 2.6e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 KIR63521.1 - 0.15 11.4 0.0 0.24 10.6 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Dockerin_1 PF00404.18 KIR63522.1 - 0.054 13.7 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Dockerin type I domain Colicin_V PF02674.16 KIR63522.1 - 0.17 11.8 7.8 0.57 10.1 7.8 1.7 1 1 0 1 1 1 0 Colicin V production protein DUF4190 PF13828.6 KIR63522.1 - 1.2 8.9 20.1 12 5.7 20.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) UbiA PF01040.18 KIR63522.1 - 2.4 7.4 13.3 8.7 5.6 13.3 1.8 1 1 0 1 1 1 0 UbiA prenyltransferase family H2TH PF06831.14 KIR63523.1 - 7e-18 64.4 0.0 9.9e-18 63.9 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 KIR63523.1 - 1.1e-06 28.4 4.8 2e-06 27.5 4.8 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Fapy_DNA_glyco PF01149.24 KIR63523.1 - 1.9e-05 25.2 0.0 4.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Pyr_redox_2 PF07992.14 KIR63524.1 - 1.4e-56 191.9 0.2 1.8e-56 191.6 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR63524.1 - 8.3e-21 74.3 1.6 1.1e-18 67.6 0.9 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIR63524.1 - 5e-19 68.6 0.0 1.5e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DAO PF01266.24 KIR63524.1 - 4.3e-09 36.4 8.4 0.00084 19.0 0.6 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIR63524.1 - 4.3e-08 32.8 0.0 1.4e-05 24.5 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR63524.1 - 9.1e-08 32.2 0.7 0.018 15.3 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR63524.1 - 8.6e-06 25.1 9.7 0.67 9.0 0.0 4.8 4 1 1 5 5 5 3 FAD binding domain HI0933_like PF03486.14 KIR63524.1 - 2.8e-05 23.0 0.5 0.44 9.2 0.2 3.3 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_9 PF13454.6 KIR63524.1 - 0.00011 22.2 4.8 1.1 9.2 0.2 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KIR63524.1 - 0.00071 19.0 5.0 0.13 11.6 0.1 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KIR63524.1 - 0.0021 17.2 2.3 0.097 11.7 0.6 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 KIR63524.1 - 0.0021 17.3 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KIR63524.1 - 0.0033 16.5 0.4 0.093 11.8 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KIR63524.1 - 0.0059 16.5 0.5 0.0095 15.8 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIR63524.1 - 0.0069 16.8 0.5 0.016 15.6 0.1 1.8 2 0 0 2 2 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 KIR63524.1 - 0.01 16.1 0.1 0.055 13.7 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KIR63524.1 - 0.026 13.8 5.0 4.1 6.7 0.1 3.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KIR63524.1 - 0.036 13.5 0.2 0.061 12.8 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIR63524.1 - 0.077 12.6 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.11 KIR63524.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 KIR63524.1 - 0.39 9.5 2.9 3.1 6.5 0.8 2.6 2 1 1 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KIR63524.1 - 1.5 8.0 6.4 0.19 10.9 0.5 2.2 2 1 1 3 3 3 0 FAD binding domain CBM_2 PF00553.19 KIR63526.1 - 8.3e-26 90.2 6.2 8.3e-26 90.2 6.2 2.1 2 0 0 2 2 2 1 Cellulose binding domain Glyco_hydro_18 PF00704.28 KIR63526.1 - 1.4e-25 90.6 0.0 6e-24 85.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF11 PF01345.18 KIR63526.1 - 0.0003 21.0 1.7 0.0051 17.1 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function DUF11 CBM49 PF09478.10 KIR63526.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 GFO_IDH_MocA PF01408.22 KIR63527.1 - 1.6e-22 80.6 0.1 2.7e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KIR63527.1 - 0.0014 19.2 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 KIR63527.1 - 0.04 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 KIR63527.1 - 0.088 13.5 0.2 0.69 10.6 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain ParE_toxin PF05016.15 KIR63528.1 - 6.8e-10 39.4 0.1 7.3e-10 39.3 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Gp49 PF05973.14 KIR63528.1 - 0.053 13.7 0.0 0.057 13.6 0.0 1.1 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) TetR_C_1 PF02909.17 KIR63529.1 - 3.1e-11 43.3 0.0 4.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR63529.1 - 8.2e-07 28.7 0.5 1.7e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Beta_helix PF13229.6 KIR63530.1 - 5e-10 39.4 12.0 1.6e-09 37.8 8.0 2.6 2 1 0 2 2 2 1 Right handed beta helix region CBM_6 PF03422.15 KIR63530.1 - 1.9e-09 37.9 4.3 1.9e-09 37.9 4.3 2.5 3 0 0 3 3 3 1 Carbohydrate binding module (family 6) CBM_35 PF16990.5 KIR63530.1 - 2.6e-09 37.4 3.7 5.6e-09 36.3 3.7 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) DUF5010_C PF18099.1 KIR63530.1 - 1.7e-05 24.9 1.6 0.0003 20.9 1.6 2.4 2 0 0 2 2 2 1 DUF5010 C-terminal domain Chondroitinas_B PF14592.6 KIR63530.1 - 5.6e-05 22.2 0.0 0.00014 20.9 0.0 1.6 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.11 KIR63530.1 - 0.00059 19.3 6.1 0.00059 19.3 6.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) CBM60 PF16841.5 KIR63530.1 - 0.0011 19.4 1.0 0.13 12.7 0.2 3.0 2 1 1 3 3 3 2 Ca-dependent carbohydrate-binding module xylan-binding DUF4397 PF14344.6 KIR63530.1 - 0.08 13.7 5.4 0.38 11.5 1.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4397) GHMP_kinases_N PF00288.26 KIR63531.1 - 4.9e-10 39.5 0.8 4.9e-10 39.5 0.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIR63531.1 - 7.6e-06 26.2 0.2 5.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal DUF742 PF05331.11 KIR63533.1 - 2.3e-34 117.6 0.7 2.6e-34 117.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) MarR_2 PF12802.7 KIR63533.1 - 3.9e-05 23.4 0.5 6.5e-05 22.7 0.5 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KIR63533.1 - 0.024 14.5 0.4 0.039 13.8 0.4 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR63533.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SpoIIE PF07228.12 KIR63534.1 - 3.1e-42 144.7 1.3 6.1e-42 143.7 1.3 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GAF PF01590.26 KIR63534.1 - 0.0016 19.0 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KIR63534.1 - 0.023 15.0 1.3 0.023 15.0 1.3 2.9 2 1 0 3 3 3 0 GAF domain MFS_1 PF07690.16 KIR63535.1 - 4.1e-38 131.2 57.5 1.8e-36 125.8 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR63535.1 - 3.6e-06 26.1 10.6 3.6e-06 26.1 10.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter Alpha-amylase PF00128.24 KIR63536.1 - 5.8e-74 249.6 0.0 1.1e-73 248.8 0.0 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 KIR63536.1 - 7.9e-05 22.9 0.0 0.00035 20.8 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) GHL5 PF14872.6 KIR63536.1 - 0.022 12.9 0.0 0.034 12.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 TspO_MBR PF03073.15 KIR63537.1 - 1.2e-43 148.4 22.5 1.4e-43 148.2 22.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Thymidylate_kin PF02223.17 KIR63538.1 - 8.1e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KIR63538.1 - 7e-06 26.6 0.2 0.0013 19.3 0.2 3.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR63538.1 - 0.0028 17.9 0.1 0.0042 17.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR63538.1 - 0.0066 16.6 0.7 0.035 14.3 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR63538.1 - 0.019 15.4 1.1 0.036 14.5 0.7 1.9 1 1 1 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 KIR63538.1 - 0.029 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KIR63538.1 - 0.058 13.8 0.0 0.2 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIR63538.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KIR63538.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 KIR63538.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 KIR63538.1 - 0.17 12.1 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEC-1_N PF04625.13 KIR63538.1 - 1.1 8.2 8.2 1.4 7.8 8.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SIS PF01380.22 KIR63539.1 - 6.4e-26 90.8 0.2 1.1e-25 90.0 0.2 1.4 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 KIR63539.1 - 3.3e-16 59.0 0.0 6.2e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 KIR63539.1 - 5.6e-09 36.1 3.1 6.7e-07 29.4 0.3 2.7 1 1 1 2 2 2 2 SIS domain SIS_2 PF13580.6 KIR63540.1 - 3.4e-07 30.4 0.2 6.5e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 KIR63540.1 - 5.9e-06 26.2 0.0 3.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 SIS domain UBA_4 PF14555.6 KIR63540.1 - 0.0026 17.6 0.0 0.0076 16.0 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain GDE_N_bis PF14742.6 KIR63541.1 - 7e-40 136.7 0.1 9.7e-40 136.2 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of (some) glycogen debranching enzymes GDE_C PF06202.14 KIR63541.1 - 3.4e-13 49.3 0.0 1.1e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase HTH_17 PF12728.7 KIR63545.1 - 5.8e-11 42.4 0.0 8.3e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_AlpA PF05930.12 KIR63545.1 - 8.3e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) HTH_22 PF13309.6 KIR63545.1 - 0.00089 19.3 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_8 PF02954.19 KIR63545.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 KIR63545.1 - 0.0032 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR63545.1 - 0.017 14.8 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 KIR63545.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KIR63545.1 - 0.024 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KIR63545.1 - 0.034 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AbiEi_4 PF13338.6 KIR63545.1 - 0.073 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin TPR_7 PF13176.6 KIR63546.1 - 0.038 14.0 5.5 33 4.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIR63546.1 - 0.041 13.8 15.5 0.31 11.0 3.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rhodanese PF00581.20 KIR63547.1 - 8.4e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HNH_5 PF14279.6 KIR63550.1 - 9.3e-15 54.2 0.1 1.4e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 KIR63550.1 - 2.8e-10 40.2 0.2 4.3e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 KIR63550.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease zf-RVT PF13966.6 KIR63550.1 - 0.011 16.5 0.0 0.53 11.0 0.0 2.4 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase MG2 PF01835.19 KIR63551.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 MG2 domain Aminotran_5 PF00266.19 KIR63552.1 - 1.7e-12 47.0 0.0 2.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Shadoo PF14999.6 KIR63552.1 - 0.52 10.4 4.5 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Aldedh PF00171.22 KIR63553.1 - 1e-155 518.8 0.1 1.2e-155 518.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIR63553.1 - 0.029 13.4 0.0 0.061 12.4 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) RETICULATA-like PF11891.8 KIR63553.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein RETICULATA-related CBM_2 PF00553.19 KIR63554.1 - 4.6e-22 78.2 6.7 9.5e-22 77.2 6.7 1.5 1 0 0 1 1 1 1 Cellulose binding domain fn3 PF00041.21 KIR63554.1 - 0.0011 19.3 0.2 0.16 12.4 0.0 2.6 2 1 0 2 2 2 1 Fibronectin type III domain PhoD_N PF16655.5 KIR63554.1 - 0.0028 18.1 0.0 0.0076 16.8 0.0 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KIR63554.1 - 0.035 14.7 0.4 0.09 13.4 0.0 1.9 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Big_1 PF02369.16 KIR63554.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.9 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 1) NUDIX PF00293.28 KIR63555.1 - 7e-19 68.2 0.0 8.4e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Helitron_like_N PF14214.6 KIR63557.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus tRNA-synt_1b PF00579.25 KIR64176.1 - 6.9e-67 225.8 0.0 8.6e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FixG_C PF11614.8 KIR64177.1 - 1.2e-05 25.5 0.0 0.53 10.5 0.0 4.1 3 1 1 4 4 4 2 IG-like fold at C-terminal of FixG, putative oxidoreductase fn3_6 PF17766.1 KIR64177.1 - 2.1e-05 24.6 0.0 6.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type-III domain Cohesin PF00963.18 KIR64177.1 - 0.034 14.4 0.1 0.12 12.7 0.1 1.9 1 0 0 1 1 1 0 Cohesin domain Baseplate_J PF04865.14 KIR64177.1 - 0.059 12.5 0.7 4.4 6.4 0.1 2.6 2 0 0 2 2 2 0 Baseplate J-like protein ASH PF15780.5 KIR64177.1 - 0.084 13.1 0.4 0.46 10.7 0.1 2.3 2 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin fn3_5 PF06280.12 KIR64177.1 - 0.1 13.3 3.6 33 5.2 0.0 3.8 3 2 0 4 4 4 0 Fn3-like domain DUF11 PF01345.18 KIR64177.1 - 0.21 11.9 11.9 3.9 7.8 4.6 4.3 2 2 0 2 2 2 0 Domain of unknown function DUF11 GerE PF00196.19 KIR64178.1 - 4.6e-15 54.9 0.1 8.1e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 KIR64178.1 - 3.5e-05 23.4 0.0 0.00012 21.8 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR64178.1 - 0.0029 17.3 4.7 0.0055 16.4 0.0 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR64178.1 - 0.016 15.1 0.2 0.066 13.1 0.1 1.9 1 1 1 2 2 2 0 ECF sigma factor HTH_28 PF13518.6 KIR64178.1 - 0.024 14.8 0.1 0.24 11.6 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 KIR64178.1 - 0.049 13.6 0.2 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.16 KIR64178.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 PD40 PF07676.12 KIR64179.1 - 3.2e-38 128.9 26.4 4.1e-07 29.8 0.0 10.4 10 0 0 10 10 10 8 WD40-like Beta Propeller Repeat DUF11 PF01345.18 KIR64179.1 - 2.7e-12 46.8 20.9 3.2e-10 40.2 3.7 3.2 3 1 0 3 3 2 2 Domain of unknown function DUF11 NPCBM_assoc PF10633.9 KIR64179.1 - 1.9e-08 34.5 18.0 2.3e-05 24.6 0.6 4.4 4 1 1 5 5 5 2 NPCBM-associated, NEW3 domain of alpha-galactosidase DPPIV_N PF00930.21 KIR64179.1 - 1.9e-07 30.1 0.0 0.012 14.4 0.0 6.1 6 2 0 7 7 7 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region CARDB PF07705.11 KIR64179.1 - 5.2e-06 26.6 0.0 0.0043 17.3 0.0 2.6 2 0 0 2 2 2 2 CARDB DUF824 PF05688.11 KIR64179.1 - 0.0013 18.5 0.9 0.086 12.7 0.0 2.7 2 0 0 2 2 2 1 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 KIR64179.1 - 0.017 15.1 3.6 7.2 6.7 0.0 4.7 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 1) Pectate_lyase22 PF14583.6 KIR64179.1 - 0.028 13.1 0.0 0.25 10.0 0.0 2.4 2 1 1 3 3 3 0 Oligogalacturonate lyase BatD PF13584.6 KIR64179.1 - 0.16 10.7 0.0 3.3 6.4 0.0 2.0 2 0 0 2 2 2 0 Oxygen tolerance Big_3_5 PF16640.5 KIR64179.1 - 0.57 10.4 8.9 13 6.1 2.0 3.8 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Invasin_D3 PF09134.10 KIR64179.1 - 1.8 8.9 6.0 27 5.2 0.1 4.0 4 1 0 4 4 4 0 Invasin, domain 3 Phage_sheath_1 PF04984.14 KIR64180.1 - 3.7e-35 121.3 0.0 5.8e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 KIR64180.1 - 1.7e-20 72.9 0.0 2.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain Phage_T4_gp19 PF06841.12 KIR64181.1 - 3.5e-30 104.6 0.1 4e-30 104.4 0.1 1.0 1 0 0 1 1 1 1 T4-like virus tail tube protein gp19 zinc_ribbon_4 PF13717.6 KIR64182.1 - 0.073 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Phage_T4_gp19 PF06841.12 KIR64184.1 - 3.4e-23 82.0 0.0 3.9e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 T4-like virus tail tube protein gp19 LysM PF01476.20 KIR64185.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 LysM domain Phage_P2_GpU PF06995.11 KIR64185.1 - 0.0003 20.4 0.0 0.0048 16.5 0.0 2.1 1 1 0 1 1 1 1 Phage P2 GpU Phage_GPD PF05954.11 KIR64186.1 - 1.8e-08 34.0 0.6 3e-08 33.3 0.6 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) DUF2345 PF10106.9 KIR64186.1 - 0.0089 15.9 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2345) GPW_gp25 PF04965.14 KIR64187.1 - 1.2e-23 82.7 0.0 1.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Baseplate_J PF04865.14 KIR64188.1 - 1.6e-18 66.8 0.5 1.5e-15 57.1 0.1 2.2 2 0 0 2 2 2 2 Baseplate J-like protein T6SS_TssF PF05947.12 KIR64188.1 - 0.016 13.8 0.1 0.025 13.1 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssF Tail_P2_I PF09684.10 KIR64189.1 - 7.8e-11 42.0 0.0 9.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) Dak1 PF02733.17 KIR64189.1 - 0.069 12.0 0.1 0.092 11.6 0.1 1.1 1 0 0 1 1 1 0 Dak1 domain Sirohm_synth_M PF14824.6 KIR64189.1 - 0.21 11.1 1.9 0.32 10.5 0.1 2.1 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central BTAD PF03704.17 KIR64190.1 - 5.5e-12 46.3 12.4 8.9e-12 45.7 12.4 1.3 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KIR64190.1 - 3.8e-08 33.3 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_14 PF13428.6 KIR64190.1 - 4 8.5 15.3 0.45 11.5 8.1 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 KIR64191.1 - 6e-26 91.2 0.0 8.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 KIR64191.1 - 2e-21 76.0 5.0 4.4e-21 74.9 5.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR64191.1 - 9.3e-09 35.2 0.0 0.0049 16.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_ISL3 PF13542.6 KIR64191.1 - 0.014 14.8 3.7 1.5 8.3 0.9 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF4031 PF13223.6 KIR64191.1 - 0.057 13.6 0.4 1 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) 4HBT PF03061.22 KIR64192.1 - 4.5e-09 36.5 0.4 9.5e-09 35.5 0.1 1.7 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 KIR64192.1 - 0.0004 20.7 0.1 0.00054 20.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Aminotran_4 PF01063.19 KIR64193.1 - 9e-28 97.7 0.0 1.1e-27 97.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ketoacyl-synt PF00109.26 KIR64194.1 - 2.2e-47 161.8 7.0 2.2e-47 161.8 7.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIR64194.1 - 1.4e-34 118.6 2.4 2.5e-34 117.8 2.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KIR64194.1 - 5.3e-06 26.0 2.1 0.00015 21.3 0.3 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KIR64194.1 - 0.023 15.2 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Thiolase_C PF02803.18 KIR64194.1 - 0.059 13.0 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KIR64194.1 - 0.28 11.0 7.6 2.4 8.0 0.6 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Condensation PF00668.20 KIR64195.1 - 2.1e-12 46.5 0.0 6.8e-08 31.6 0.0 2.0 2 0 0 2 2 2 2 Condensation domain p450 PF00067.22 KIR64196.1 - 9e-28 97.2 0.0 3.7e-24 85.3 0.1 2.9 2 1 0 2 2 2 2 Cytochrome P450 ABC_tran PF00005.27 KIR64197.1 - 2e-24 86.7 0.0 3.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIR64197.1 - 1.3e-05 25.0 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_25 PF13481.6 KIR64197.1 - 0.00063 19.4 0.3 0.11 12.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIR64197.1 - 0.00081 19.3 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR64197.1 - 0.003 18.0 2.9 0.031 14.7 0.2 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_23 PF13476.6 KIR64197.1 - 0.0062 17.1 0.0 0.0098 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DLIC PF05783.11 KIR64197.1 - 0.014 14.2 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SMC_N PF02463.19 KIR64197.1 - 0.015 14.8 0.1 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR64197.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIR64197.1 - 0.079 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KIR64197.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIR64197.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3331 PF11811.8 KIR64197.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) AAA PF00004.29 KIR64197.1 - 0.13 12.7 0.0 0.84 10.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIR64197.1 - 0.14 12.0 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 NTPase adh_short_C2 PF13561.6 KIR64198.1 - 6.4e-64 215.7 0.2 7.8e-64 215.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR64198.1 - 2.9e-42 144.3 0.1 3.7e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR64198.1 - 8.6e-11 42.1 0.2 1.1e-10 41.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR64198.1 - 0.026 14.0 0.4 0.072 12.5 0.4 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIR64198.1 - 0.036 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KIR64198.1 - 0.15 11.8 0.7 0.36 10.6 0.4 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acyl-CoA_dh_1 PF00441.24 KIR64199.1 - 6.3e-40 136.8 7.8 9.4e-40 136.3 7.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KIR64199.1 - 3.9e-22 79.0 12.0 7.2e-22 78.1 12.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR64199.1 - 4e-18 65.4 0.1 1.1e-17 64.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIR64199.1 - 4.9e-17 62.6 0.4 2.4e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain EPSP_synthase PF00275.20 KIR64200.1 - 1e-78 264.9 0.0 1.5e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) AMP-binding PF00501.28 KIR64200.1 - 1.2e-78 264.7 0.0 1.6e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR64200.1 - 2.4e-11 44.4 0.2 2.4e-11 44.4 0.2 3.1 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR64201.1 - 6.9e-12 45.5 0.7 8.8e-12 45.2 0.7 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1493 PF07377.12 KIR64201.1 - 0.026 15.0 0.3 0.039 14.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) YdiH PF15930.5 KIR64201.1 - 0.032 14.4 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Radical_SAM PF04055.21 KIR64202.1 - 0.00014 22.3 0.0 0.00025 21.5 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KIR64202.1 - 0.00039 20.7 0.0 0.0011 19.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIR64202.1 - 0.001 19.2 0.0 0.0044 17.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain AMP-binding PF00501.28 KIR64203.1 - 2.9e-84 283.1 0.0 3.5e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR64203.1 - 9.2e-06 26.6 0.1 2.4e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR64204.1 - 5.8e-14 52.2 0.1 6.6e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_19 PF04672.12 KIR64205.1 - 3e-96 322.0 0.0 3.4e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_31 PF13847.6 KIR64205.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SGL PF08450.12 KIR64206.1 - 5.6e-43 147.3 0.0 7.3e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIR64206.1 - 2.1e-07 30.9 0.0 0.0014 18.7 0.0 2.9 2 1 0 2 2 2 2 Strictosidine synthase Arylesterase PF01731.20 KIR64206.1 - 2.6e-05 24.4 0.0 0.00028 21.0 0.0 2.7 3 2 0 3 3 3 1 Arylesterase Lactonase PF10282.9 KIR64206.1 - 7.4e-05 22.2 0.1 0.11 11.7 0.0 2.2 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Phytase-like PF13449.6 KIR64206.1 - 0.026 14.5 0.0 0.89 9.4 0.0 2.4 1 1 0 2 2 2 0 Esterase-like activity of phytase NHL PF01436.21 KIR64206.1 - 0.029 14.4 4.7 9.6 6.5 0.2 4.3 4 0 0 4 4 4 0 NHL repeat PD40 PF07676.12 KIR64206.1 - 0.11 12.5 0.4 35 4.5 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ldl_recept_b PF00058.17 KIR64206.1 - 0.45 11.0 3.1 3.3 8.3 0.1 3.4 4 1 0 4 4 4 0 Low-density lipoprotein receptor repeat class B GSDH PF07995.11 KIR64207.1 - 8.5e-64 215.9 0.1 1.3e-63 215.3 0.1 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase fn3 PF00041.21 KIR64207.1 - 5.4e-09 36.3 3.8 2.3e-06 27.8 0.5 2.5 2 0 0 2 2 2 2 Fibronectin type III domain RGI_lyase PF18370.1 KIR64207.1 - 0.00066 19.9 3.2 0.51 10.7 0.5 2.5 2 0 0 2 2 2 2 Rhamnogalacturonan I lyases beta-sheet domain ChitinaseA_N PF08329.10 KIR64207.1 - 0.039 13.6 3.1 0.88 9.2 0.7 2.2 1 1 1 2 2 2 0 Chitinase A, N-terminal domain Phosphoesterase PF04185.14 KIR64207.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoesterase family SmpA_OmlA PF04355.13 KIR64207.1 - 0.17 11.7 0.7 1 9.2 0.1 2.4 3 0 0 3 3 3 0 SmpA / OmlA family DUF2369 PF10179.9 KIR64207.1 - 0.17 12.3 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Big_6 PF17936.1 KIR64207.1 - 0.24 11.7 12.2 2.7 8.3 0.1 3.0 2 1 0 2 2 2 0 Bacterial Ig domain Peptidase_S8 PF00082.22 KIR64208.1 - 2.1e-20 73.2 0.5 5.4e-20 71.8 0.5 1.6 1 0 0 1 1 1 1 Subtilase family Big_7 PF17957.1 KIR64208.1 - 0.00071 20.3 11.0 0.5 11.2 0.6 4.8 2 1 2 4 4 4 2 Bacterial Ig domain PKD PF00801.20 KIR64208.1 - 0.097 12.5 7.3 1.8 8.4 1.3 3.6 3 0 0 3 3 3 0 PKD domain HTH_18 PF12833.7 KIR64209.1 - 1.2e-22 80.0 0.5 1.2e-22 80.0 0.5 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR64209.1 - 6.8e-14 51.5 0.0 8.4e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_5 PF01022.20 KIR64209.1 - 0.11 12.4 0.0 19 5.2 0.0 2.5 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Response_reg PF00072.24 KIR64210.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR64210.1 - 5.1e-12 45.2 0.0 9.7e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR64210.1 - 4.7e-07 29.4 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KIR64210.1 - 0.0016 18.2 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR64210.1 - 0.0025 17.3 0.5 0.006 16.1 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 KIR64210.1 - 0.032 14.3 0.3 0.13 12.3 0.1 2.2 1 1 1 2 2 2 0 Winged helix-turn helix PAS_4 PF08448.10 KIR64210.1 - 0.049 13.9 0.2 0.18 12.1 0.2 1.9 1 1 1 2 2 2 0 PAS fold HisKA_3 PF07730.13 KIR64211.1 - 3.6e-13 49.8 4.2 1.2e-12 48.1 4.2 2.0 1 0 0 1 1 1 1 Histidine kinase Sensor PF13796.6 KIR64211.1 - 2.2e-11 44.1 28.3 2.2e-11 44.1 28.3 3.1 2 2 2 4 4 4 1 Putative sensor HATPase_c_2 PF13581.6 KIR64211.1 - 9.5e-06 25.6 0.1 2.2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR64211.1 - 0.00018 22.0 0.0 0.0012 19.4 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AHSA1 PF08327.11 KIR64212.1 - 1.5e-20 73.7 2.9 1.7e-20 73.5 2.9 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KIR64212.1 - 0.00017 21.9 5.3 0.00023 21.5 5.3 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR64212.1 - 0.084 13.1 1.6 1.1 9.5 0.5 2.1 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Chalcone_3 PF16036.5 KIR64212.1 - 0.094 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Chalcone isomerase-like HTH_20 PF12840.7 KIR64213.1 - 2.6e-08 33.8 1.9 2.6e-08 33.8 1.9 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR64213.1 - 0.0012 18.7 1.0 0.0022 17.8 1.0 1.5 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KIR64213.1 - 0.0078 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_41 PF14502.6 KIR64213.1 - 0.011 15.3 0.1 0.06 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain FtsK_gamma PF09397.10 KIR64213.1 - 0.12 12.2 1.9 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 Ftsk gamma domain YwpF PF14183.6 KIR64213.1 - 0.15 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 YwpF-like protein DUF4129 PF13559.6 KIR64213.1 - 0.87 9.9 8.4 9.6 6.5 8.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) TSNR_N PF04705.12 KIR64214.1 - 1.8e-39 134.3 0.1 3.5e-39 133.3 0.1 1.5 1 0 0 1 1 1 1 Thiostrepton-resistance methylase, N terminus SpoU_methylase PF00588.19 KIR64214.1 - 2.1e-28 99.2 0.0 1e-27 97.0 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KIR64214.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding RibD_C PF01872.17 KIR64215.1 - 2.9e-20 72.9 0.0 4.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain HpcH_HpaI PF03328.14 KIR64216.1 - 1.2e-08 34.4 0.1 3.2e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_62 PF03664.13 KIR64217.1 - 5.3e-152 504.8 15.6 5.3e-152 504.8 15.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 62 CBM_2 PF00553.19 KIR64217.1 - 3.9e-32 110.6 14.1 3.9e-32 110.6 14.1 2.6 3 0 0 3 3 3 1 Cellulose binding domain NmrA PF05368.13 KIR64218.1 - 4.5e-09 36.2 0.1 0.00085 18.9 0.0 2.3 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KIR64218.1 - 2.7e-08 33.9 3.6 1.7e-05 24.8 0.4 2.9 2 1 1 3 3 3 2 NAD(P)H-binding Epimerase PF01370.21 KIR64218.1 - 4.7e-05 23.0 0.7 0.022 14.2 0.3 3.1 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family YcxB PF14317.6 KIR64220.1 - 4.9e-09 35.8 0.0 6.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 YcxB-like protein ATP-synt_I PF03899.15 KIR64220.1 - 0.025 14.9 0.9 0.041 14.2 0.9 1.3 1 0 0 1 1 1 0 ATP synthase I chain TMEM100 PF16311.5 KIR64220.1 - 0.12 11.9 0.3 0.18 11.4 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 LapA_dom PF06305.11 KIR64220.1 - 9.3 6.1 6.1 0.93 9.3 0.7 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Laminin_G_3 PF13385.6 KIR64221.1 - 0.07 13.3 1.3 0.11 12.6 1.2 1.5 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Pro_Al_protease PF02983.14 KIR64221.1 - 0.15 12.2 0.3 30 4.8 0.0 3.1 3 0 0 3 3 3 0 Alpha-lytic protease prodomain PD40 PF07676.12 KIR64222.1 - 0.00022 21.1 10.9 0.038 13.9 0.1 5.3 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat PrsW-protease PF13367.6 KIR64223.1 - 3.5e-27 95.2 18.6 3.5e-27 95.2 18.6 1.6 2 0 0 2 2 2 1 PrsW family intramembrane metalloprotease SBP_bac_1 PF01547.25 KIR64224.1 - 1.1e-23 84.7 4.1 1.1e-23 84.7 4.1 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR64225.1 - 3.8e-32 111.5 47.0 2.6e-18 66.4 12.0 3.6 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component TraQ PF09679.10 KIR64225.1 - 0.063 13.2 1.0 0.26 11.2 1.0 2.0 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) F420H2_quin_red PF04075.14 KIR64226.1 - 5.9e-44 149.3 0.2 6.5e-44 149.2 0.2 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF1117 PF06547.12 KIR64226.1 - 0.0064 17.0 0.2 0.076 13.6 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1117) SHMT PF00464.19 KIR64228.1 - 1.8e-142 474.7 0.0 2.1e-142 474.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KIR64228.1 - 1.1e-08 34.7 0.0 1.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIR64228.1 - 2.1e-06 27.3 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIR64228.1 - 0.00028 20.3 0.0 0.00048 19.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase LDcluster4 PF18306.1 KIR64228.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family ATP-grasp_4 PF13535.6 KIR64229.1 - 6.8e-14 51.8 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 KIR64229.1 - 9e-12 45.4 4.8 1.8e-11 44.4 0.9 3.3 4 0 0 4 4 4 1 ATP-grasp N-terminal domain ATP-grasp_3 PF02655.14 KIR64229.1 - 1.6e-07 31.6 0.0 2.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIR64229.1 - 1.8e-06 27.8 0.1 1.9e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KIR64229.1 - 3.9e-05 23.3 0.0 0.00035 20.2 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KIR64229.1 - 8.7e-05 22.1 0.0 0.058 12.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Glyco_trans_4_4 PF13579.6 KIR64229.1 - 0.0015 19.0 10.6 0.0039 17.7 10.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR64229.1 - 0.0045 17.0 0.2 0.0087 16.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ATP-grasp_5 PF13549.6 KIR64229.1 - 0.015 14.7 0.3 0.057 12.9 0.3 1.9 1 1 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 KIR64229.1 - 0.074 12.8 0.0 0.33 10.7 0.0 1.9 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MFS_1 PF07690.16 KIR64230.1 - 1.4e-10 40.6 53.6 2.6e-10 39.7 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIR64230.1 - 0.0004 18.9 12.2 0.0004 18.9 12.2 2.9 2 1 1 3 3 3 2 Transmembrane secretion effector DUF5538 PF17692.1 KIR64230.1 - 0.003 17.6 1.0 0.0096 16.0 0.3 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5538) TetR_C_14 PF17754.1 KIR64232.1 - 1.5e-16 60.3 8.5 3.1e-16 59.3 8.5 1.6 1 0 0 1 1 1 1 MftR C-terminal domain TetR_N PF00440.23 KIR64232.1 - 1e-12 47.6 0.1 1e-12 47.6 0.1 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 KIR64232.1 - 6.7e-05 22.6 0.7 0.0022 17.7 0.0 2.8 2 1 1 3 3 3 1 Homeodomain-like domain HTH_AraC PF00165.23 KIR64232.1 - 0.017 15.2 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_29 PF13551.6 KIR64232.1 - 0.036 14.1 1.0 0.43 10.6 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn helix LacI PF00356.21 KIR64232.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family CO_deh_flav_C PF03450.17 KIR64232.1 - 2 8.7 6.7 7.9 6.7 0.1 3.1 3 1 1 4 4 4 0 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_3 PF01494.19 KIR64233.1 - 1.7e-68 231.5 0.0 2.1e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR64233.1 - 1e-06 28.6 7.2 0.0014 18.3 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR64233.1 - 4.8e-06 25.5 0.1 0.019 13.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KIR64233.1 - 1.3e-05 24.6 0.0 0.019 14.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR64233.1 - 8.5e-05 22.7 0.1 0.0002 21.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIR64233.1 - 0.00019 20.8 0.1 0.059 12.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIR64233.1 - 0.00021 21.8 0.0 0.13 12.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR64233.1 - 0.00067 18.8 0.6 0.072 12.2 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 KIR64233.1 - 0.001 19.1 1.2 0.062 13.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KIR64233.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KIR64233.1 - 0.0011 18.1 0.3 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 KIR64233.1 - 0.013 14.8 0.2 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIR64233.1 - 0.03 13.6 0.0 0.094 12.0 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIR64233.1 - 0.044 12.6 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TPR_12 PF13424.6 KIR64234.1 - 6.4e-26 90.5 26.1 1.3e-07 31.8 0.5 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIR64234.1 - 1.2e-13 50.0 19.5 0.14 12.3 0.0 7.7 7 1 0 7 7 7 6 Tetratricopeptide repeat CHAT PF12770.7 KIR64234.1 - 1.7e-13 50.7 0.1 1.5e-12 47.6 0.1 2.2 1 1 0 1 1 1 1 CHAT domain SNAP PF14938.6 KIR64234.1 - 7.5e-10 38.7 0.7 0.019 14.4 0.0 3.1 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 KIR64234.1 - 1.5e-09 37.2 1.3 0.088 12.7 0.0 6.3 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIR64234.1 - 6.8e-08 32.2 12.4 8.2e-06 25.4 1.9 2.6 1 1 2 3 3 3 3 MalT-like TPR region TPR_10 PF13374.6 KIR64234.1 - 1.9e-06 27.5 25.5 0.048 13.5 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.9 KIR64234.1 - 5.8e-06 26.1 0.0 0.015 15.0 0.0 3.8 2 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 KIR64234.1 - 0.0012 18.9 0.2 26 5.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIR64234.1 - 0.011 15.4 9.1 0.93 9.2 0.4 4.5 5 0 0 5 5 5 0 TPR repeat TPR_7 PF13176.6 KIR64234.1 - 0.036 14.1 12.1 23 5.3 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIR64234.1 - 0.11 13.2 52.8 0.093 13.4 0.6 7.7 2 1 7 9 9 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIR64234.1 - 0.17 11.3 1.0 2.4 7.7 0.0 2.8 3 0 0 3 3 3 0 SHNi-TPR TPR_4 PF07721.14 KIR64234.1 - 3.5 8.5 38.3 0.33 11.7 0.2 9.1 7 2 1 8 8 8 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 KIR64236.1 - 1.3e-27 96.9 11.4 2.4e-27 96.0 11.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIR64236.1 - 1.8e-05 25.3 0.0 4.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 S8_pro-domain PF16470.5 KIR64236.1 - 0.13 13.0 0.1 2.4 9.0 0.1 2.3 1 1 0 1 1 1 0 Peptidase S8 pro-domain Cellulase PF00150.18 KIR64237.1 - 5.8e-66 222.8 6.6 7.6e-66 222.4 6.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_2 PF00553.19 KIR64237.1 - 2.6e-26 91.9 11.8 2.6e-26 91.9 11.8 2.5 2 0 0 2 2 2 1 Cellulose binding domain Response_reg PF00072.24 KIR64238.1 - 2.7e-30 104.8 0.0 4.1e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR64238.1 - 1.4e-21 76.3 0.0 6.3e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 KIR64239.1 - 7.9e-26 90.8 0.0 1.5e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR64239.1 - 2e-13 50.5 1.4 2e-13 50.5 1.4 2.2 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 KIR64239.1 - 4.1e-10 39.6 0.1 1.5e-09 37.8 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KIR64239.1 - 2.1e-05 24.5 0.1 6.9e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR64239.1 - 0.0093 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KIR64239.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 GHKL domain TPR_12 PF13424.6 KIR64240.1 - 1.2e-27 96.0 31.8 3.9e-14 52.7 5.4 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIR64240.1 - 1e-24 85.3 9.7 4.1e-06 26.4 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIR64240.1 - 1.5e-22 77.8 18.8 3.1e-05 23.7 1.5 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIR64240.1 - 3.8e-15 54.7 20.4 1e-05 25.2 0.1 5.5 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIR64240.1 - 1.1e-14 53.3 3.4 0.0046 17.1 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIR64240.1 - 2.2e-11 43.2 27.0 6e-05 22.8 0.4 6.3 4 1 1 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 KIR64240.1 - 1.2e-08 34.5 0.0 2.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KIR64240.1 - 2.7e-07 31.1 2.3 5.9e-07 30.0 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIR64240.1 - 5.9e-07 29.8 0.0 8.4e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.6 KIR64240.1 - 1.5e-06 28.6 37.1 0.3 12.0 1.1 8.1 6 1 1 7 7 6 3 Tetratricopeptide repeat SNAP PF14938.6 KIR64240.1 - 1.4e-05 24.7 0.7 0.00014 21.4 0.0 2.1 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KIR64240.1 - 0.0001 22.9 3.0 0.0001 22.9 3.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.12 KIR64240.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.14 KIR64240.1 - 0.00094 19.6 18.0 0.0022 18.4 6.0 8.1 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIR64240.1 - 0.0017 18.6 9.8 1.6 9.3 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIR64240.1 - 0.0033 17.1 10.4 0.062 13.0 1.7 4.6 5 1 1 6 6 6 1 TPR repeat TPR_6 PF13174.6 KIR64240.1 - 0.0046 17.5 14.8 1.6 9.5 0.6 7.2 8 0 0 8 8 6 1 Tetratricopeptide repeat AAA_25 PF13481.6 KIR64240.1 - 0.015 14.9 0.1 0.077 12.6 0.1 2.2 1 0 0 1 1 1 0 AAA domain MarR_2 PF12802.7 KIR64240.1 - 0.026 14.4 1.4 0.16 11.9 0.6 3.0 2 1 0 2 2 2 0 MarR family MIT PF04212.18 KIR64240.1 - 0.046 13.8 6.5 2.4 8.3 0.3 3.7 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KIR64240.1 - 0.083 13.4 7.1 0.49 10.9 2.7 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIR64240.1 - 0.11 12.6 3.1 6.4 6.8 0.1 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DUF5112 PF17139.4 KIR64240.1 - 0.28 10.6 1.2 5.1 6.5 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5112) DUF5113 PF17140.4 KIR64240.1 - 2 8.2 5.2 23 4.7 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5113) Fis1_TPR_C PF14853.6 KIR64240.1 - 2 8.6 7.3 12 6.0 0.1 4.2 5 0 0 5 5 3 0 Fis1 C-terminal tetratricopeptide repeat Trypsin PF00089.26 KIR64241.1 - 1e-06 28.7 0.5 3.8e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Trypsin Inhibitor_I36 PF03995.13 KIR64242.1 - 3.9e-11 42.7 0.2 5.1e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase inhibitor family I36 COesterase PF00135.28 KIR64243.1 - 1.3e-86 291.5 0.0 1.1e-85 288.5 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIR64243.1 - 7.5e-10 39.0 0.5 1.2e-09 38.3 0.5 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIR64243.1 - 0.00012 21.6 0.2 0.00019 21.0 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pectate_lyase_3 PF12708.7 KIR64243.1 - 0.007 16.2 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Pectate lyase superfamily protein fn3 PF00041.21 KIR64245.1 - 0.0013 19.0 0.0 0.042 14.2 0.0 2.7 1 1 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 KIR64245.1 - 0.021 15.4 0.1 0.33 11.5 0.1 2.6 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3_2 PF16893.5 KIR64245.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Cytidylate_kin2 PF13189.6 KIR64246.1 - 2.7e-06 27.7 0.0 3.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.6 KIR64246.1 - 2.4e-05 24.8 0.0 3.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KIR64246.1 - 0.0045 16.3 0.2 0.0096 15.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KIR64246.1 - 0.0061 17.1 0.0 0.014 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIR64246.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Cytidylate_kin PF02224.18 KIR64246.1 - 0.0065 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 KIR64246.1 - 0.011 16.0 0.0 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR64246.1 - 0.022 14.9 0.1 0.091 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KIR64246.1 - 0.027 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KIR64246.1 - 0.062 13.2 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KIR64246.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIR64246.1 - 0.12 12.9 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIR64246.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 KIR64246.1 - 0.14 11.8 0.0 1.7 8.3 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase HisKA_3 PF07730.13 KIR64247.1 - 6e-08 33.1 13.4 1.8e-06 28.3 3.2 4.5 4 1 0 4 4 4 2 Histidine kinase HATPase_c_2 PF13581.6 KIR64247.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR64247.1 - 0.064 13.8 0.0 4.3 7.9 0.0 2.8 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4096 PF13340.6 KIR64249.1 - 2.7e-23 81.9 0.1 6.3e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 KIR64249.1 - 1.9e-11 44.0 2.0 1.9e-10 40.8 1.9 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KIR64249.1 - 0.00048 20.4 0.0 0.00089 19.6 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain TSC22 PF01166.18 KIR64250.1 - 0.015 15.6 0.1 0.32 11.3 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family HAUS5 PF14817.6 KIR64250.1 - 0.12 11.1 0.9 0.17 10.6 0.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 CPBP PF02517.16 KIR64251.1 - 4.8e-14 52.5 6.8 4.8e-14 52.5 6.8 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2981 PF11200.8 KIR64251.1 - 1.4 8.6 3.1 2.1 8.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Globin PF00042.22 KIR64252.1 - 2.3e-13 50.7 0.0 5.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KIR64252.1 - 2e-12 47.3 0.0 3.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIR64252.1 - 1e-10 42.2 0.0 2.4e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KIR64252.1 - 0.005 16.9 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Pep_deformylase PF01327.21 KIR64253.1 - 1.1e-28 99.8 0.0 2.2e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Polypeptide deformylase HTH_31 PF13560.6 KIR64253.1 - 2.6e-10 40.5 0.8 7.3e-10 39.1 0.8 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64253.1 - 4.2e-05 23.5 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR64253.1 - 0.0003 20.8 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4824 PF16106.5 KIR64253.1 - 0.006 15.9 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4824) HTH_37 PF13744.6 KIR64253.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_23 PF13489.6 KIR64255.1 - 4.7e-10 39.5 0.0 1e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR64255.1 - 1.2e-07 32.4 0.0 1.9e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64255.1 - 6.6e-07 29.9 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR64255.1 - 1.4e-06 28.9 0.0 2.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIR64255.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 KIR64255.1 - 0.0083 15.5 0.0 0.037 13.4 0.0 1.8 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family XhoI PF04555.13 KIR64255.1 - 0.063 13.2 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease XhoI PBP PF01161.20 KIR64256.1 - 5.2e-37 127.1 0.0 8.9e-37 126.4 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein PIN PF01850.21 KIR64257.1 - 0.00029 21.3 0.0 0.00039 20.9 0.0 1.2 1 0 0 1 1 1 1 PIN domain RHH_5 PF07878.11 KIR64258.1 - 4.5e-07 29.7 0.7 4.5e-07 29.7 0.7 1.7 2 0 0 2 2 2 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 CopG_antitoxin PF12441.8 KIR64258.1 - 0.00044 20.7 0.0 0.00067 20.1 0.0 1.3 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system RHH_3 PF12651.7 KIR64258.1 - 0.0046 16.9 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix domain RHH_1 PF01402.21 KIR64258.1 - 0.06 13.3 1.8 0.1 12.6 0.2 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family THDPS_M PF14789.6 KIR64258.1 - 0.12 12.5 0.8 0.17 12.0 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase middle DUF5539 PF17693.1 KIR64260.1 - 0.0064 16.2 0.2 0.0076 15.9 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5539) Lar_restr_allev PF14354.6 KIR64260.1 - 0.039 14.3 0.2 0.075 13.4 0.2 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar MctB PF11382.8 KIR64262.1 - 0.16 11.7 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF3307 PF11750.8 KIR64263.1 - 6.1e-08 32.8 0.0 8.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3307) YwiC PF14256.6 KIR64263.1 - 0.1 12.9 10.5 0.07 13.4 4.0 2.1 2 0 0 2 2 2 0 YwiC-like protein FtsK_SpoIIIE PF01580.18 KIR64265.1 - 0.00063 19.2 0.0 0.0037 16.7 0.0 2.0 1 1 0 1 1 1 1 FtsK/SpoIIIE family DUF3631 PF12307.8 KIR64265.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) DCX PF03607.17 KIR64265.1 - 0.2 11.8 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Doublecortin Anti-TRAP PF15777.5 KIR64266.1 - 5.1e-05 23.2 0.5 7.5e-05 22.6 0.5 1.2 1 0 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ_CXXCXGXG PF00684.19 KIR64266.1 - 7.1e-05 23.1 0.7 9.3e-05 22.7 0.7 1.2 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KIR64266.1 - 0.00025 21.1 0.1 0.00028 20.9 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4326 PF14216.6 KIR64268.1 - 7e-22 78.0 0.0 7.8e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) Prim-Pol PF09250.11 KIR64270.1 - 1.1e-40 139.6 3.2 1.1e-40 139.6 3.2 1.5 2 0 0 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal DAP_epimerase PF01678.19 KIR64270.1 - 0.12 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase HTH_17 PF12728.7 KIR64272.1 - 3.8e-06 27.0 0.0 4.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KIR64272.1 - 0.05 13.7 0.0 0.085 13.0 0.0 1.4 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 KIR64272.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Phage_integrase PF00589.22 KIR64273.1 - 4.7e-13 49.3 0.0 1.4e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family ADH_zinc_N_2 PF13602.6 KIR64274.1 - 7.5e-28 98.2 1.5 1.7e-27 97.0 1.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR64274.1 - 1.7e-23 83.0 2.3 3.2e-23 82.1 2.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR64274.1 - 1.4e-09 37.8 0.0 1.5e-08 34.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIR64274.1 - 0.03 13.8 0.2 0.061 12.8 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase MerR-DNA-bind PF09278.11 KIR64275.1 - 2.1e-18 66.6 0.5 2.1e-18 66.6 0.5 1.5 2 0 0 2 2 2 1 MerR, DNA binding MerR_1 PF13411.6 KIR64275.1 - 1.2e-16 60.5 0.1 1.9e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR64275.1 - 2.4e-14 52.8 2.9 3.5e-14 52.3 1.5 1.9 2 0 0 2 2 2 1 MerR family regulatory protein AbiEi_4 PF13338.6 KIR64275.1 - 0.015 15.4 0.1 0.038 14.2 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_3 PF01381.22 KIR64275.1 - 0.023 14.7 0.1 0.074 13.1 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix Glycos_transf_2 PF00535.26 KIR64276.1 - 1.8e-33 115.7 0.0 2.5e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR64276.1 - 1.6e-13 51.1 0.0 1.9e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR64276.1 - 2.4e-07 30.5 0.0 3.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KIR64276.1 - 8.8e-06 26.2 0.1 1.5e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIR64276.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Myosin_N PF02736.19 KIR64277.1 - 0.0087 15.9 4.2 0.17 11.7 0.1 2.4 2 0 0 2 2 2 2 Myosin N-terminal SH3-like domain Response_reg PF00072.24 KIR64278.1 - 1.8e-25 89.3 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR64278.1 - 1.5e-24 85.8 0.1 5.5e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 KIR64278.1 - 0.00054 19.8 0.8 0.01 15.7 0.1 3.1 2 1 0 3 3 3 1 MarR family Thiolase_N PF00108.23 KIR64280.1 - 8.2e-68 228.6 0.3 1.1e-67 228.2 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR64280.1 - 1.2e-40 137.9 0.1 2.6e-40 136.9 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR64280.1 - 1.8e-05 24.5 1.1 4.5e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIR64280.1 - 0.051 13.4 0.6 2.4 8.1 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Rhomboid PF01694.22 KIR64281.1 - 1.4e-33 116.1 13.8 1.4e-33 116.1 13.8 2.5 2 1 1 3 3 3 2 Rhomboid family zf-B_box PF00643.24 KIR64281.1 - 0.0011 19.1 7.0 0.0023 18.0 7.0 1.5 1 1 0 1 1 1 1 B-box zinc finger DUF1751 PF08551.10 KIR64281.1 - 0.0048 17.4 1.0 0.0048 17.4 1.0 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Dynactin_p62 PF05502.13 KIR64281.1 - 2 7.1 4.0 2.8 6.6 4.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family Pro_isomerase PF00160.21 KIR64282.1 - 3.1e-44 151.0 0.0 3.5e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Apolipoprotein PF01442.18 KIR64283.1 - 0.047 13.6 7.7 0.034 14.0 6.2 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ATPgrasp_Ter PF15632.6 KIR64283.1 - 0.15 11.8 0.6 0.31 10.8 0.6 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Gram_pos_anchor PF00746.21 KIR64283.1 - 0.23 11.4 0.3 0.23 11.4 0.3 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif CorA PF01544.18 KIR64284.1 - 6.3e-64 216.1 0.2 7.3e-64 215.9 0.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spore_III_AB PF09548.10 KIR64284.1 - 0.019 15.1 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4533 PF15047.6 KIR64284.1 - 0.17 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Aminotran_1_2 PF00155.21 KIR64285.1 - 1.1e-34 120.2 0.0 1.2e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIR64285.1 - 3.5e-18 65.6 0.1 1.7e-17 63.4 0.1 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 KIR64285.1 - 2.4e-05 23.8 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SKIP_SNW PF02731.15 KIR64285.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 SKIP/SNW domain Inositol_P PF00459.25 KIR64286.1 - 1.2e-28 100.4 0.1 2e-28 99.7 0.1 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Glyco_tran_28_C PF04101.16 KIR64287.1 - 5.3e-16 59.0 0.0 5.9e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Alg14 PF08660.11 KIR64288.1 - 1.4e-08 34.9 0.0 1.7e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 KIR64288.1 - 0.0032 17.5 0.3 0.075 13.1 0.0 2.1 1 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Wzz PF02706.15 KIR64290.1 - 0.00011 22.4 0.1 0.00024 21.4 0.1 1.6 1 0 0 1 1 1 1 Chain length determinant protein GNVR PF13807.6 KIR64290.1 - 0.00024 21.0 0.1 0.0024 17.8 0.0 2.4 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase DUF4140 PF13600.6 KIR64290.1 - 0.0067 16.8 2.4 0.0067 16.8 2.4 2.0 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 KIR64290.1 - 0.026 14.7 0.2 0.048 13.9 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPPK_C PF12555.8 KIR64290.1 - 0.72 9.9 5.4 0.19 11.8 1.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF3048 PF11258.8 KIR64291.1 - 1.3e-12 48.0 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3048) N-terminal domain DUF3048_C PF17479.2 KIR64291.1 - 9.3e-07 29.2 0.0 1.9e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3048) C-terminal domain Sulfotransfer_3 PF13469.6 KIR64292.1 - 1.4e-14 55.0 0.3 1.6e-06 28.7 0.1 3.0 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR64292.1 - 3e-14 53.2 0.0 4.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KIR64292.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase domain SRPRB PF09439.10 KIR64292.1 - 0.04 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF5122 PF17164.4 KIR64293.1 - 1.3e-08 35.0 20.1 0.021 15.1 0.7 7.7 7 0 0 7 7 7 4 Domain of unknown function (DUF5122) beta-propeller PD40 PF07676.12 KIR64293.1 - 0.002 18.0 1.3 0.079 12.9 0.4 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40 PF00400.32 KIR64293.1 - 0.062 14.2 2.4 6.3 7.8 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat NUDIX PF00293.28 KIR64294.1 - 1e-19 70.9 0.4 1.3e-19 70.6 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIR64294.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain WHIM1 PF15612.6 KIR64295.1 - 0.093 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 NTP_transferase PF00483.23 KIR64296.1 - 1.8e-13 50.7 0.1 4.2e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR64296.1 - 1.5e-12 48.2 0.6 2.5e-12 47.5 0.6 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fe-ADH_2 PF13685.6 KIR64297.1 - 2.1e-54 184.8 2.2 2.6e-54 184.6 2.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KIR64297.1 - 1.5e-16 60.2 5.7 1.9e-16 59.9 5.7 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 KIR64297.1 - 2.5e-06 26.9 2.2 2.5e-05 23.6 1.3 2.4 2 1 0 2 2 2 1 3-dehydroquinate synthase CDP-OH_P_transf PF01066.21 KIR64298.1 - 2.6e-08 34.5 0.8 2.6e-08 34.5 0.8 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TetR_C_14 PF17754.1 KIR64298.1 - 0.017 15.0 2.3 0.017 15.0 2.3 2.4 2 0 0 2 2 2 0 MftR C-terminal domain DUF3379 PF11859.8 KIR64298.1 - 3.2 7.0 4.1 0.96 8.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) Abhydrolase_1 PF00561.20 KIR64299.1 - 1.7e-24 86.9 1.7 4.9e-24 85.4 1.7 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR64299.1 - 4.2e-14 53.7 17.5 5.6e-14 53.3 17.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR64299.1 - 8.2e-07 28.5 0.5 5.1e-06 25.9 0.2 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIR64299.1 - 0.02 13.6 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family EHN PF06441.12 KIR64299.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus VCBS PF13517.6 KIR64300.1 - 2.1e-29 101.9 81.3 1.1e-06 29.1 2.5 7.8 1 1 7 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KIR64300.1 - 3.1e-21 75.2 30.1 0.00059 19.9 0.6 7.7 7 0 0 7 7 7 4 FG-GAP repeat Sen15 PF09631.10 KIR64300.1 - 1e-08 35.4 0.1 5.3 7.4 0.0 4.5 4 0 0 4 4 4 4 Sen15 protein DUF3224 PF11528.8 KIR64300.1 - 0.00063 19.6 0.7 38 4.1 0.0 5.1 1 1 6 7 7 7 0 Protein of unknown function (DUF3224) BCL_N PF04714.13 KIR64300.1 - 0.0041 17.1 0.5 16 5.6 0.0 4.1 4 0 0 4 4 4 1 BCL7, N-terminal conserver region NLPC_P60 PF00877.19 KIR64300.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 NlpC/P60 family NCE101 PF11654.8 KIR64300.1 - 0.13 11.9 5.8 86 3.0 0.1 4.3 4 0 0 4 4 4 0 Non-classical export protein 1 DUF397 PF04149.12 KIR64302.1 - 8.9e-22 76.9 0.7 1e-21 76.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_17 PF12728.7 KIR64303.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain Phage_AlpA PF05930.12 KIR64303.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_31 PF13560.6 KIR64304.1 - 5e-10 39.6 3.2 5e-10 39.6 3.2 4.2 4 2 1 5 5 5 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64304.1 - 0.02 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.7 KIR64304.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_12 PF13424.6 KIR64304.1 - 0.18 12.1 15.9 1.5 9.2 0.5 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Cupin_2 PF07883.11 KIR64306.1 - 6.7e-21 73.8 0.5 1.8e-20 72.4 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KIR64306.1 - 7.9e-08 32.0 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KIR64306.1 - 2.9e-06 26.9 0.0 6.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KIR64306.1 - 8.8e-06 25.9 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 KIR64306.1 - 6.2e-05 22.9 0.1 7.7e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain EutQ PF06249.12 KIR64306.1 - 0.00041 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.18 KIR64306.1 - 0.0093 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 KIR64306.1 - 0.072 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_7 PF12973.7 KIR64306.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 ChrR Cupin-like domain ARD PF03079.14 KIR64306.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Peptidase_M24 PF00557.24 KIR64307.1 - 2.1e-38 132.2 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 HTH_31 PF13560.6 KIR64308.1 - 6e-09 36.1 0.9 1.4e-08 34.9 0.9 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64308.1 - 1.5e-06 28.1 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 KIR64308.1 - 0.0026 18.1 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KIR64308.1 - 0.0032 16.9 0.3 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_19 PF12844.7 KIR64308.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_trans_4_4 PF13579.6 KIR64309.1 - 7.9e-21 75.2 4.4 7.9e-21 75.2 4.4 2.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR64309.1 - 4.9e-17 62.4 2.8 4.9e-17 62.4 2.8 2.6 3 1 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIR64309.1 - 5.8e-17 62.4 0.5 1.3e-13 51.5 0.0 2.7 2 1 1 3 3 3 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIR64309.1 - 2.8e-14 53.0 0.0 4.3e-12 45.9 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR64309.1 - 0.003 17.6 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KIR64309.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4428 PF14471.6 KIR64309.1 - 0.087 12.8 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) H2TH PF06831.14 KIR64310.1 - 2.4e-17 62.7 0.0 3.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KIR64310.1 - 3.1e-17 63.3 0.0 7e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 KIR64310.1 - 4.7e-08 32.7 0.8 8.3e-08 31.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-TFIIB PF13453.6 KIR64310.1 - 0.00038 19.7 2.8 0.00074 18.8 2.8 1.5 1 0 0 1 1 1 1 Transcription factor zinc-finger zf-RRN7 PF11781.8 KIR64310.1 - 0.052 13.2 0.6 0.11 12.2 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FbpA PF05833.11 KIR64310.1 - 0.07 11.9 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Zn-ribbon_8 PF09723.10 KIR64310.1 - 0.38 10.9 2.4 2 8.6 2.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DUF2752 PF10825.8 KIR64310.1 - 1.9 8.6 4.7 0.63 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Bac_transf PF02397.16 KIR64311.1 - 7.5e-65 218.0 0.0 1.4e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 KIR64311.1 - 5.1e-09 36.4 0.1 9e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 CoA-binding domain His_kinase PF06580.13 KIR64312.1 - 1.6e-23 82.8 0.0 2.5e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 KIR64312.1 - 2.5e-08 34.4 0.0 4.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR64312.1 - 2.3e-05 24.4 0.0 6.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR64312.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 KIR64312.1 - 0.072 13.7 0.4 0.14 12.7 0.4 1.6 1 0 0 1 1 1 0 GAF domain GAF_3 PF13492.6 KIR64312.1 - 0.097 13.0 0.6 0.26 11.7 0.6 1.7 1 0 0 1 1 1 0 GAF domain LytTR PF04397.15 KIR64313.1 - 6.4e-23 80.8 0.0 1.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 LytTr DNA-binding domain Response_reg PF00072.24 KIR64313.1 - 1.8e-22 79.6 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_24 PF13578.6 KIR64313.1 - 0.14 13.1 0.9 1.3 10.1 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain Response_reg PF00072.24 KIR64314.1 - 1.3e-25 89.7 0.0 2.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR64314.1 - 2.3e-22 78.9 0.0 4.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DNAPolymera_Pol PF11590.8 KIR64314.1 - 0.0082 16.0 0.3 0.026 14.4 0.3 1.9 1 0 0 1 1 1 1 DNA polymerase catalytic subunit Pol MarR_2 PF12802.7 KIR64314.1 - 0.038 13.9 2.1 0.31 11.0 0.1 3.0 3 0 0 3 3 3 0 MarR family B12-binding PF02310.19 KIR64314.1 - 0.042 13.9 0.0 0.3 11.1 0.0 2.3 2 1 0 2 2 2 0 B12 binding domain HGTP_anticodon PF03129.20 KIR64314.1 - 0.052 13.7 0.0 0.46 10.7 0.0 2.3 2 1 1 3 3 3 0 Anticodon binding domain LytR_C PF13399.6 KIR64314.1 - 0.087 13.8 0.4 0.25 12.3 0.0 2.0 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator DUF4173 PF13777.6 KIR64315.1 - 1.8e-59 200.4 12.7 1.8e-59 200.4 12.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4173) DUF4153 PF13687.6 KIR64315.1 - 0.0037 16.9 9.1 0.0074 15.9 9.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4153) GPDPase_memb PF10110.9 KIR64315.1 - 5.6 5.6 5.1 13 4.5 0.1 2.2 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF485 PF04341.12 KIR64316.1 - 5.9e-06 26.2 1.2 8.2e-06 25.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF485 CCB1 PF12046.8 KIR64316.1 - 0.088 12.1 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF4131 PF13567.6 KIR64316.1 - 0.25 11.0 4.4 0.18 11.4 3.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SSF PF00474.17 KIR64317.1 - 7.5e-41 140.3 30.8 3.3e-26 92.1 12.6 2.4 2 1 0 2 2 2 2 Sodium:solute symporter family B12D PF06522.11 KIR64317.1 - 0.063 13.1 0.4 0.063 13.1 0.4 3.6 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ABC_tran PF00005.27 KIR64318.1 - 4.8e-20 72.5 0.0 6.5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR64318.1 - 9.4e-09 35.5 0.1 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIR64318.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KIR64318.1 - 0.23 12.0 0.0 0.33 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Polyketide_cyc2 PF10604.9 KIR64320.1 - 1.3e-12 48.1 4.0 1.6e-12 47.9 4.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR64320.1 - 0.044 14.0 0.2 0.066 13.4 0.2 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Flavin_Reduct PF01613.18 KIR64321.1 - 8.9e-18 64.8 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF485 PF04341.12 KIR64322.1 - 2.5e-31 107.5 2.4 2.9e-31 107.3 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 Phage_holin_2_4 PF16082.5 KIR64322.1 - 0.032 13.9 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Phage_holin_3_6 PF07332.11 KIR64322.1 - 0.053 13.6 0.5 0.068 13.2 0.5 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_2_3 PF16080.5 KIR64322.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 RseC_MucC PF04246.12 KIR64322.1 - 0.2 11.6 0.6 0.27 11.2 0.6 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SSF PF00474.17 KIR64323.1 - 6.8e-91 305.1 43.1 1.4e-90 304.1 43.1 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 KIR64323.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2818) GDP_Man_Dehyd PF16363.5 KIR64324.1 - 5e-51 174.1 0.0 1.8e-50 172.3 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIR64324.1 - 2.6e-46 158.0 0.0 3.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR64324.1 - 1.1e-07 31.3 0.0 1.4e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIR64324.1 - 2.4e-07 30.1 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIR64324.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIR64324.1 - 0.00023 20.4 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIR64324.1 - 0.0066 15.6 0.0 0.5 9.5 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KIR64324.1 - 0.047 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KIR64324.1 - 0.25 10.9 0.1 0.5 9.9 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family LytR_cpsA_psr PF03816.14 KIR64325.1 - 5e-44 150.1 0.0 7.7e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_cpsA_psr PF03816.14 KIR64326.1 - 2.1e-36 125.4 0.0 3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain GDPD PF03009.17 KIR64327.1 - 6.7e-41 140.7 0.0 1.1e-40 140.0 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIR64327.1 - 4.5e-07 30.1 1.7 6e-07 29.7 0.4 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family HATPase_c_2 PF13581.6 KIR64328.1 - 9.8e-08 32.0 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GPHH PF16905.5 KIR64328.1 - 0.023 14.4 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated HATPase_c PF02518.26 KIR64328.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidinotransf PF02274.17 KIR64330.1 - 4.3e-92 308.8 0.0 4.9e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase PAS PF00989.25 KIR64332.1 - 0.0025 17.8 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold ACT_7 PF13840.6 KIR64333.1 - 1.5e-14 53.6 0.0 2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 ACT domain PDT PF00800.18 KIR64334.1 - 5.8e-46 156.6 0.0 7.3e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KIR64334.1 - 2.9e-07 30.1 0.0 5.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF4880 PF16220.5 KIR64334.1 - 0.49 10.3 8.1 0.27 11.2 2.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) AIM24 PF01987.17 KIR64335.1 - 1.1e-32 113.5 1.6 1.2e-32 113.3 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 OsmC PF02566.19 KIR64336.1 - 1.9e-20 73.2 0.1 2.4e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 OsmC-like protein Trp_oprn_chp PF09534.10 KIR64337.1 - 0.017 14.9 12.8 0.023 14.5 12.8 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) STAG PF08514.11 KIR64337.1 - 0.3 11.0 0.0 0.43 10.5 0.0 1.1 1 0 0 1 1 1 0 STAG domain Hydrolase_3 PF08282.12 KIR64338.1 - 6.3e-42 144.1 0.0 2.3e-41 142.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KIR64338.1 - 8.9e-12 45.1 0.1 5e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KIR64338.1 - 1.2e-07 32.2 1.4 0.00013 22.3 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64338.1 - 5.4e-05 23.7 0.5 0.041 14.3 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIR64338.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIR64338.1 - 0.018 15.1 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR64339.1 - 1.8e-52 178.6 0.0 2.1e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KIR64339.1 - 1e-13 51.4 0.0 2.2e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KIR64339.1 - 6e-08 33.2 1.0 0.01 16.2 0.0 3.2 1 1 2 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64339.1 - 1.6e-07 31.9 4.8 0.016 15.6 0.1 3.3 1 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIR64339.1 - 0.00029 20.9 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KIR64339.1 - 0.036 13.2 0.0 0.087 11.9 0.0 1.6 2 0 0 2 2 2 0 Trehalose-phosphatase Peptidase_S9 PF00326.21 KIR64340.1 - 2.1e-10 40.4 0.0 5.3e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIR64340.1 - 1.4e-08 34.3 1.1 5.9e-06 25.7 0.6 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIR64340.1 - 1.1e-07 32.6 26.0 2.7e-05 24.9 22.6 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIR64340.1 - 1.4e-06 28.3 6.5 3.2e-05 23.9 6.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIR64340.1 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KIR64340.1 - 5.5e-06 26.2 0.0 0.00067 19.4 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIR64340.1 - 0.0082 16.0 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KIR64340.1 - 0.0097 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Ser_hydrolase PF06821.13 KIR64340.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase DUF2920 PF11144.8 KIR64340.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S15 PF02129.18 KIR64340.1 - 0.19 11.3 0.4 0.76 9.3 0.5 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peripla_BP_6 PF13458.6 KIR64341.1 - 1e-51 176.6 9.4 1.3e-51 176.3 9.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KIR64341.1 - 4.4e-09 35.8 0.0 6.9e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein domain ANF_receptor PF01094.28 KIR64341.1 - 1.6e-07 30.8 0.0 7e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Receptor family ligand binding region TAT_signal PF10518.9 KIR64341.1 - 0.096 12.6 1.7 0.22 11.5 1.7 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Amidinotransf PF02274.17 KIR64342.1 - 4.6e-13 49.0 0.0 8.6e-13 48.1 0.0 1.6 1 1 0 1 1 1 1 Amidinotransferase HTH_AsnC-type PF13404.6 KIR64343.1 - 6.6e-15 54.7 4.8 7.5e-15 54.5 3.2 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KIR64343.1 - 2.6e-14 52.9 0.1 4e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 KIR64343.1 - 9.1e-12 44.4 0.1 1.6e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR64343.1 - 0.0023 17.8 0.4 0.0023 17.8 0.4 2.4 2 1 0 2 2 2 1 MarR family HTH_20 PF12840.7 KIR64343.1 - 0.02 15.0 0.5 0.046 13.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 KIR64343.1 - 0.03 14.2 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 KIR64343.1 - 0.035 13.9 0.2 0.22 11.4 0.3 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Rrf2 PF02082.20 KIR64343.1 - 0.041 14.2 0.0 3.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator HTH_Crp_2 PF13545.6 KIR64343.1 - 0.042 13.8 0.2 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_47 PF16221.5 KIR64343.1 - 0.08 12.5 0.3 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 winged helix-turn-helix Beta_propel PF09826.9 KIR64344.1 - 9e-117 391.0 0.0 1.1e-116 390.8 0.0 1.0 1 0 0 1 1 1 1 Beta propeller domain NTP_transf_3 PF12804.7 KIR64346.1 - 4e-26 92.3 10.6 4.9e-26 92.0 10.6 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Flavoprotein PF02441.19 KIR64348.1 - 3.1e-25 88.8 0.0 3.9e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein AIRC PF00731.20 KIR64349.1 - 0.18 11.4 1.8 0.53 9.9 0.1 2.1 2 0 0 2 2 2 0 AIR carboxylase Sigma70_r4_2 PF08281.12 KIR64350.1 - 5.9e-13 48.3 0.1 1.1e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR64350.1 - 2.5e-10 39.7 0.1 4.2e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR64350.1 - 8.2e-08 31.9 3.1 1.4e-07 31.2 3.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 GerE PF00196.19 KIR64350.1 - 0.0018 17.8 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 KIR64350.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 KIR64350.1 - 0.0027 17.4 0.1 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain CysG_dimeriser PF10414.9 KIR64350.1 - 0.49 10.2 4.7 2.3 8.0 0.2 2.9 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region FdhD-NarQ PF02634.15 KIR64351.1 - 3.1e-79 266.0 0.0 3.6e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family NUDIX PF00293.28 KIR64352.1 - 4.7e-08 33.2 0.4 6.4e-08 32.7 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain CBM_2 PF00553.19 KIR64353.1 - 5.6e-23 81.2 11.2 5.6e-23 81.2 11.2 2.9 3 1 0 3 3 3 1 Cellulose binding domain Trypsin PF00089.26 KIR64353.1 - 0.038 13.8 4.6 0.038 13.8 0.9 2.5 2 1 0 2 2 2 0 Trypsin dCMP_cyt_deam_1 PF00383.23 KIR64354.1 - 3.5e-12 46.1 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIR64354.1 - 4.8e-12 45.8 0.0 5.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase DUF4192 PF13830.6 KIR64355.1 - 1.7e-84 284.6 29.9 1.9e-84 284.4 29.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) TPR_14 PF13428.6 KIR64355.1 - 0.13 13.2 0.4 0.13 13.2 0.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Fructosamin_kin PF03881.14 KIR64356.1 - 2.5e-45 154.9 0.0 3.3e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KIR64356.1 - 4.9e-11 43.0 11.8 8e-11 42.3 11.8 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIR64356.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Mob_synth_C PF06463.13 KIR64357.1 - 1.1e-32 112.6 0.0 4.5e-30 104.2 0.0 2.2 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KIR64357.1 - 2.3e-30 106.1 0.0 8.1e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KIR64357.1 - 8.8e-05 22.8 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIR64357.1 - 0.00016 21.8 0.0 0.00024 21.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain CMD PF02627.20 KIR64357.1 - 0.1 12.7 5.6 3 7.9 0.1 3.7 4 1 0 4 4 4 0 Carboxymuconolactone decarboxylase family Metallophos PF00149.28 KIR64358.1 - 1.5e-11 45.2 0.0 3.6e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR64358.1 - 2.6e-05 24.5 0.0 5.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4418 PF14387.6 KIR64358.1 - 0.53 10.5 1.9 0.97 9.6 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) FtsX PF02687.21 KIR64358.1 - 0.8 10.2 4.5 1.6 9.3 4.5 1.5 1 0 0 1 1 1 0 FtsX-like permease family UvrD-helicase PF00580.21 KIR64359.1 - 2.7e-58 198.0 0.0 3.3e-30 105.7 0.1 2.1 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KIR64359.1 - 4.3e-40 137.4 0.0 6.8e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 KIR64359.1 - 6.2e-31 108.0 0.0 4.6e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KIR64359.1 - 4e-09 36.2 0.0 9.5e-08 31.8 0.0 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KIR64359.1 - 5e-07 29.6 0.0 4.8e-06 26.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIR64359.1 - 0.00029 20.6 0.0 0.4 10.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PHP_C PF13263.6 KIR64359.1 - 0.0078 16.0 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 PHP-associated AAA_16 PF13191.6 KIR64359.1 - 0.0085 16.5 3.1 0.01 16.2 0.8 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KIR64361.1 - 3.3e-21 76.4 1.0 7.4e-21 75.3 1.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR64361.1 - 6e-05 23.3 0.1 0.0014 19.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain MarR PF01047.22 KIR64361.1 - 0.0042 17.0 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 MarR family AAA_30 PF13604.6 KIR64361.1 - 0.0054 16.5 0.2 0.015 15.0 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIR64361.1 - 0.0068 16.7 0.0 0.032 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIR64361.1 - 0.0074 16.3 0.1 0.051 13.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain DUF2791 PF10923.8 KIR64361.1 - 0.026 13.4 0.1 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA PF00004.29 KIR64361.1 - 0.031 14.7 0.0 6 7.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIR64361.1 - 0.05 13.5 0.0 0.39 10.6 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 KIR64361.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RsgA_GTPase PF03193.16 KIR64361.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Acetyltransf_9 PF13527.7 KIR64362.1 - 4.9e-10 39.6 0.0 5.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR64362.1 - 3.7e-09 36.8 0.0 4.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR64362.1 - 2.3e-06 27.9 0.0 3.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR64362.1 - 0.0062 16.5 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DoxX PF07681.12 KIR64363.1 - 1e-15 58.1 1.0 2e-15 57.1 1.0 1.5 1 0 0 1 1 1 1 DoxX HR_lesion PF05514.11 KIR64363.1 - 4.3e-05 23.7 0.0 6.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 HR-like lesion-inducing GT87 PF09594.10 KIR64364.1 - 1.9e-58 198.0 31.4 1.9e-58 198.0 31.4 3.5 4 0 0 4 4 4 1 Glycosyltransferase family 87 TMEM238 PF15125.6 KIR64364.1 - 0.0082 16.3 1.8 0.78 10.0 0.1 3.3 2 0 0 2 2 2 2 TMEM238 protein family MoaE PF02391.17 KIR64365.1 - 7.1e-35 119.7 3.6 8.2e-35 119.5 3.6 1.0 1 0 0 1 1 1 1 MoaE protein MoeA_N PF03453.17 KIR64366.1 - 1.6e-28 99.5 1.5 1.6e-28 99.5 1.5 2.2 3 0 0 3 3 3 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KIR64366.1 - 1.3e-15 57.3 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KIR64366.1 - 3.3e-10 40.0 0.2 1e-09 38.4 0.2 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ADH_zinc_N PF00107.26 KIR64366.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MoaC PF01967.21 KIR64367.1 - 2e-47 160.7 1.0 2.3e-47 160.5 1.0 1.0 1 0 0 1 1 1 1 MoaC family EAL PF00563.20 KIR64368.1 - 5e-70 235.7 0.0 8.7e-70 234.9 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR64368.1 - 1.8e-41 141.5 0.0 4.9e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Bax1-I PF01027.20 KIR64368.1 - 3 7.6 7.5 5.8 6.7 7.5 1.4 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 GT87 PF09594.10 KIR64369.1 - 5.4e-16 59.0 48.4 5.4e-16 59.0 48.4 3.7 2 2 2 4 4 4 2 Glycosyltransferase family 87 Pribosyltran PF00156.27 KIR64370.1 - 1.1e-21 77.0 0.1 1.4e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIR64370.1 - 3.3e-05 23.4 0.3 6e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Unstab_antitox PF09720.10 KIR64370.1 - 0.0067 16.5 1.0 0.013 15.5 1.0 1.5 1 0 0 1 1 1 1 Putative addiction module component ADH_zinc_N PF00107.26 KIR64370.1 - 0.015 15.3 0.5 0.031 14.3 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Haem_oxygenas_2 PF14518.6 KIR64370.1 - 0.036 13.8 0.2 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme Oxidored_nitro PF00148.19 KIR64370.1 - 0.037 12.8 0.2 0.051 12.3 0.2 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AAA_33 PF13671.6 KIR64370.1 - 0.25 11.5 3.0 0.17 12.0 1.0 1.7 2 1 0 2 2 2 0 AAA domain zf-TFIIB PF13453.6 KIR64371.1 - 3.3e-18 64.7 1.0 4.3e-18 64.4 1.0 1.2 1 0 0 1 1 1 1 Transcription factor zinc-finger Totivirus_coat PF05518.11 KIR64371.1 - 0.0064 14.6 7.8 0.0074 14.4 7.8 1.0 1 0 0 1 1 1 1 Totivirus coat protein Cytochrom_c3_2 PF14537.6 KIR64371.1 - 0.016 15.7 0.1 0.023 15.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c3 Zn_Tnp_IS1595 PF12760.7 KIR64371.1 - 0.05 13.6 1.3 0.088 12.8 1.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DnaJ_CXXCXGXG PF00684.19 KIR64371.1 - 0.084 13.3 0.9 0.15 12.4 0.9 1.4 1 0 0 1 1 1 0 DnaJ central domain MDMPI_N PF11716.8 KIR64372.1 - 2.8e-14 54.0 20.9 2.8e-14 54.0 20.9 2.2 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DnaB_C PF03796.15 KIR64373.1 - 1.2e-98 329.6 1.4 5.6e-87 291.3 0.3 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain DnaB PF00772.21 KIR64373.1 - 2.2e-33 114.4 0.0 1.1e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 KIR64373.1 - 3e-09 36.7 0.5 1.6e-06 27.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain LAGLIDADG_3 PF14528.6 KIR64373.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 LAGLIDADG-like domain ATPase PF06745.13 KIR64373.1 - 0.0045 16.4 0.3 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 KaiC Tudor_2 PF18104.1 KIR64373.1 - 0.017 14.8 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain PSY3 PF16836.5 KIR64373.1 - 0.23 11.0 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Ribosomal_L9_C PF03948.14 KIR64374.1 - 1.1e-26 93.1 0.0 1.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 KIR64374.1 - 9.9e-22 76.2 0.1 2.8e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_S18 PF01084.20 KIR64375.1 - 2e-24 85.5 1.1 2.6e-24 85.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Peptidase_C92 PF05708.12 KIR64375.1 - 0.016 15.3 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family SpoVIF PF14069.6 KIR64375.1 - 0.072 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F EF-hand_7 PF13499.6 KIR64375.1 - 0.099 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain pair Ribosomal_S6 PF01250.17 KIR64376.1 - 4.3e-28 97.4 0.0 4.8e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 AP_endonuc_2 PF01261.24 KIR64377.1 - 7.2e-26 90.9 1.8 1e-25 90.4 1.8 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RMMBL PF07521.12 KIR64377.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain GT87 PF09594.10 KIR64379.1 - 8.4e-11 42.0 38.3 8.4e-11 42.0 38.3 3.1 2 1 0 3 3 3 1 Glycosyltransferase family 87 Mannosyl_trans PF05007.13 KIR64379.1 - 0.0067 16.3 3.1 0.42 10.4 1.2 2.3 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) DUF2142 PF09913.9 KIR64379.1 - 0.062 12.2 25.4 0.03 13.2 22.3 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2142) MASE3 PF17159.4 KIR64379.1 - 0.17 11.4 10.7 2.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Membrane-associated sensor domain Transgly PF00912.22 KIR64380.1 - 2.9e-62 209.3 2.3 2.9e-62 209.3 0.5 1.8 2 0 0 2 2 2 1 Transglycosylase Transpeptidase PF00905.22 KIR64380.1 - 1.8e-28 99.6 0.9 2.8e-28 99.0 0.9 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain DUF5318 PF17249.2 KIR64381.1 - 3.6e-65 217.7 0.1 4.2e-65 217.4 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5318) zf-LITAF-like PF10601.9 KIR64381.1 - 0.21 11.9 1.1 0.32 11.3 1.1 1.5 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain PadR PF03551.14 KIR64382.1 - 1.1e-16 60.5 0.3 7.3e-16 57.9 0.3 2.1 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KIR64382.1 - 0.00069 19.7 0.1 0.19 12.0 0.0 3.2 2 1 0 2 2 2 1 Winged helix DNA-binding domain Vir_act_alpha_C PF10400.9 KIR64382.1 - 0.011 16.4 2.0 0.011 16.4 2.0 1.9 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF5597 PF18120.1 KIR64382.1 - 0.048 13.8 0.1 0.1 12.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5597) Inos-1-P_synth PF01658.17 KIR64383.1 - 4.4e-31 107.4 0.0 1.2e-30 106.0 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 KIR64383.1 - 0.00036 20.0 0.0 0.0017 17.8 0.0 2.0 2 1 0 2 2 2 1 Myo-inositol-1-phosphate synthase DUF1611_N PF17396.2 KIR64383.1 - 0.03 14.5 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DNA_binding_1 PF01035.20 KIR64384.1 - 3.6e-29 100.7 0.0 5.1e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 KIR64384.1 - 9.4e-06 26.3 0.0 0.0094 16.7 0.0 2.2 2 0 0 2 2 2 2 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF697 PF05128.12 KIR64385.1 - 0.0096 15.6 1.0 0.017 14.8 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF697) Flot PF15975.5 KIR64386.1 - 3.8e-10 40.0 9.6 3.8e-10 40.0 9.6 5.9 2 1 4 6 6 6 1 Flotillin Band_7 PF01145.25 KIR64386.1 - 2.6e-08 34.1 55.5 2.2e-05 24.5 54.7 4.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF1319 PF07028.11 KIR64386.1 - 0.14 12.4 0.6 0.27 11.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DLIC PF05783.11 KIR64386.1 - 2.9 6.6 8.1 6.7 5.4 8.1 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TFIIA PF03153.13 KIR64386.1 - 3.5 7.5 15.5 4.5 7.2 15.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S8 PF00082.22 KIR64387.1 - 1.1e-37 129.9 13.9 2.4e-37 128.8 11.6 2.3 2 0 0 2 2 2 1 Subtilase family FRG1 PF06229.12 KIR64387.1 - 7.8e-11 42.0 2.3 1.5e-05 24.8 0.4 3.5 1 1 2 4 4 4 3 FRG1-like domain RicinB_lectin_2 PF14200.6 KIR64387.1 - 9.4e-10 39.1 6.7 9.9e-05 23.0 0.7 4.1 2 1 2 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Inhibitor_I9 PF05922.16 KIR64387.1 - 9.5e-10 39.0 0.0 2.2e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Fascin PF06268.13 KIR64387.1 - 0.00014 22.1 0.3 5.8 7.2 0.0 4.1 2 2 1 3 3 3 2 Fascin domain FGF PF00167.18 KIR64387.1 - 0.15 12.1 0.0 2.2 8.4 0.0 2.7 2 1 1 3 3 3 0 Fibroblast growth factor PolyA_pol PF01743.20 KIR64388.1 - 1e-32 113.2 0.3 2.7e-32 111.8 0.0 1.9 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KIR64388.1 - 3.2e-18 65.2 0.0 6.6e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 KIR64388.1 - 1.2e-10 41.6 0.3 3e-10 40.4 0.3 1.7 1 0 0 1 1 1 1 HD domain tRNA_NucTran2_2 PF13735.6 KIR64388.1 - 0.0021 18.1 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative MurJ PF03023.14 KIR64389.1 - 4.1e-81 272.9 31.2 5.3e-81 272.5 31.2 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 KIR64389.1 - 8.6e-07 29.1 23.0 8.6e-07 29.1 23.0 4.2 3 2 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Bac_export_2 PF01312.19 KIR64389.1 - 0.0018 17.5 0.7 0.0018 17.5 0.7 2.9 2 1 0 2 2 2 1 FlhB HrpN YscU SpaS Family MatE PF01554.18 KIR64389.1 - 0.0071 16.0 27.5 0.011 15.3 9.3 3.4 2 1 1 3 3 3 2 MatE Sigma_reg_N PF13800.6 KIR64389.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF2076 PF09849.9 KIR64389.1 - 4.5 7.2 6.9 0.9 9.5 2.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 KIR64390.1 - 8.8e-09 35.1 0.0 2.4e-08 33.7 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR64390.1 - 1.1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR64390.1 - 0.0074 16.2 1.9 0.024 14.6 1.7 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family F5_F8_type_C PF00754.25 KIR64390.1 - 0.072 13.2 0.2 0.24 11.5 0.2 1.8 1 1 0 1 1 1 0 F5/8 type C domain Sigma70_r2 PF04542.14 KIR64391.1 - 2.2e-17 62.5 5.6 3.5e-17 61.9 5.6 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR64391.1 - 2.5e-16 59.1 0.6 5.5e-16 58.0 0.3 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR64391.1 - 3.2e-08 33.0 0.7 5.6e-08 32.2 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR64391.1 - 1.5e-07 31.4 1.1 0.0043 17.0 0.0 2.1 2 0 0 2 2 2 2 ECF sigma factor GerE PF00196.19 KIR64391.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 KIR64391.1 - 0.024 14.4 3.2 0.03 14.1 0.1 2.4 2 1 0 2 2 2 0 Homeodomain-like domain Terminase_5 PF06056.12 KIR64391.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_38 PF13936.6 KIR64391.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 KIR64391.1 - 0.14 12.3 1.6 0.22 11.7 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HEAT_PBS PF03130.16 KIR64391.1 - 5.9 7.9 9.9 0.47 11.3 0.6 3.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Pyr_redox_2 PF07992.14 KIR64393.1 - 6.2e-51 173.4 2.3 7.1e-51 173.2 2.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR64393.1 - 2.7e-21 76.1 1.1 6.9e-16 58.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR64393.1 - 3.3e-20 72.4 4.8 2e-18 66.7 1.2 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR64393.1 - 4.6e-08 32.6 10.5 0.00011 21.4 0.4 4.4 2 1 3 5 5 5 3 FAD binding domain NAD_binding_8 PF13450.6 KIR64393.1 - 3.1e-05 24.1 1.4 0.00092 19.4 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIR64393.1 - 3.8e-05 22.6 0.6 0.0061 15.3 0.2 3.6 4 1 0 4 4 4 1 HI0933-like protein GIDA PF01134.22 KIR64393.1 - 5.4e-05 22.4 5.7 0.0011 18.1 0.1 4.0 3 2 2 5 5 5 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIR64393.1 - 5.5e-05 22.7 5.6 0.00015 21.3 0.6 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIR64393.1 - 6.2e-05 22.3 2.5 0.0021 17.4 0.1 2.9 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.6 KIR64393.1 - 0.00012 21.3 0.4 0.0073 15.5 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIR64393.1 - 0.00017 21.3 10.7 0.012 15.3 0.4 3.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIR64393.1 - 0.00057 20.3 0.2 0.0053 17.2 0.1 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KIR64393.1 - 0.036 12.9 6.3 0.48 9.2 0.3 3.5 3 1 1 4 4 4 0 Tryptophan halogenase FMO-like PF00743.19 KIR64393.1 - 0.064 11.7 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 KIR64393.1 - 0.075 12.3 0.7 2.9 7.0 0.2 2.5 2 1 0 2 2 2 0 FAD binding domain Thioredoxin PF00085.20 KIR64394.1 - 1.3e-31 108.7 0.0 1.4e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIR64394.1 - 6.9e-10 39.1 0.0 1.8e-08 34.6 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KIR64394.1 - 3e-09 37.3 0.1 3.4e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KIR64394.1 - 6.5e-06 26.1 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain KaiB PF07689.12 KIR64394.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 KaiB domain AhpC-TSA PF00578.21 KIR64394.1 - 6.3e-05 22.9 0.0 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR64394.1 - 6.6e-05 22.7 0.0 7.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KIR64394.1 - 7.1e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KIR64394.1 - 0.0017 18.2 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 KIR64394.1 - 0.0046 17.1 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KIR64394.1 - 0.0052 17.2 0.0 0.0066 16.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 KIR64394.1 - 0.042 13.7 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 KIR64394.1 - 0.066 12.5 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 KIR64394.1 - 0.085 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Amidase_3 PF01520.18 KIR64395.1 - 4.8e-38 131.0 0.0 6.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 KIR64395.1 - 5.3e-31 106.6 0.4 1.2e-14 54.3 0.1 3.0 3 0 0 3 3 3 2 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 KIR64395.1 - 5.4e-07 29.8 1.5 0.2 12.0 0.1 3.9 3 1 1 4 4 4 3 Predicted Peptidoglycan domain PG_binding_2 PF08823.11 KIR64395.1 - 0.0033 17.7 0.1 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Acetyltransf_1 PF00583.25 KIR64396.1 - 0.035 14.3 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.10 KIR64396.1 - 0.15 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Aminotran_1_2 PF00155.21 KIR64397.1 - 5.6e-40 137.6 0.0 6.3e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIR64397.1 - 9.1e-11 41.2 0.0 2.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KIR64397.1 - 0.19 11.0 0.1 0.45 9.8 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Dala_Dala_lig_C PF07478.13 KIR64398.1 - 2.4e-49 167.6 0.0 3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 KIR64398.1 - 1.2e-16 61.0 0.2 6.4e-09 36.2 0.1 2.3 1 1 1 2 2 2 2 D-ala D-ala ligase N-terminus ATP-grasp_3 PF02655.14 KIR64398.1 - 4.1e-08 33.4 0.0 6.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KIR64398.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KIR64398.1 - 4.8e-07 29.5 0.0 1.8e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 KIR64398.1 - 9e-05 21.8 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 KIR64398.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TTL PF03133.15 KIR64398.1 - 0.0017 17.6 0.0 0.0043 16.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.6 KIR64398.1 - 0.017 14.7 0.0 0.26 10.9 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KIR64398.1 - 0.098 11.9 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 YheC/D like ATP-grasp ParBc PF02195.18 KIR64399.1 - 9.9e-26 89.9 1.0 1.9e-25 89.0 0.3 1.8 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 KIR64399.1 - 3.8e-17 61.8 3.6 1.1e-16 60.3 3.6 1.9 1 0 0 1 1 1 1 HTH domain found in ParB protein TrmB PF01978.19 KIR64399.1 - 8.6e-05 22.3 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 KIR64399.1 - 0.0084 15.9 0.4 0.035 13.9 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 KIR64399.1 - 0.027 14.4 1.8 0.06 13.3 0.1 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Phage_TAC_11 PF11836.8 KIR64399.1 - 0.032 14.3 5.0 0.13 12.4 1.8 2.7 1 1 1 2 2 2 0 Phage tail tube protein, GTA-gp10 HTH_29 PF13551.6 KIR64399.1 - 0.094 12.7 0.1 0.094 12.7 0.1 2.7 2 1 1 3 3 3 0 Winged helix-turn helix AAA_31 PF13614.6 KIR64400.1 - 1.9e-59 200.6 0.0 2.5e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIR64400.1 - 3e-28 98.4 0.0 3.7e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KIR64400.1 - 2.7e-13 50.0 0.0 5.8e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KIR64400.1 - 3e-12 46.5 0.0 7.8e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 KIR64400.1 - 3.8e-12 46.2 0.5 3.8e-11 42.9 0.5 2.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 KIR64400.1 - 1.9e-11 43.8 0.3 4.5e-08 32.7 0.4 2.2 2 0 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.15 KIR64400.1 - 2.9e-07 30.0 0.1 8.9e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 KIR64400.1 - 0.0031 16.5 0.1 0.0059 15.6 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KIR64400.1 - 0.015 15.1 0.2 0.039 13.7 0.1 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 KIR64400.1 - 0.031 13.6 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein SRP54 PF00448.22 KIR64400.1 - 0.042 13.5 0.1 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KIR64400.1 - 0.07 12.9 0.1 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KIR64400.1 - 0.082 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain LpxK PF02606.14 KIR64400.1 - 0.095 11.8 0.3 0.14 11.2 0.3 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase R3H PF01424.22 KIR64401.1 - 1.4e-16 60.2 0.0 2.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 R3H domain KH_4 PF13083.6 KIR64401.1 - 0.0073 16.2 0.1 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 KH domain 60KD_IMP PF02096.20 KIR64402.1 - 5.2e-56 189.1 3.6 6.7e-56 188.8 3.6 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein MFS_Mycoplasma PF07672.13 KIR64402.1 - 0.0052 16.1 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Mycoplasma MFS transporter LAP1C PF05609.12 KIR64402.1 - 0.0076 15.4 0.2 0.011 14.8 0.2 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF3382 PF11862.8 KIR64402.1 - 0.011 15.9 4.0 0.018 15.3 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Peptidase_S49_N PF08496.10 KIR64402.1 - 0.074 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3487 PF11990.8 KIR64402.1 - 0.093 12.6 8.9 1.2 9.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) OSTbeta PF15048.6 KIR64402.1 - 0.1 12.7 0.4 0.31 11.2 0.3 1.7 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein Tup_N PF08581.10 KIR64402.1 - 0.19 12.1 3.1 0.29 11.4 3.1 1.2 1 0 0 1 1 1 0 Tup N-terminal Baculo_11_kDa PF06143.11 KIR64402.1 - 0.21 11.2 1.6 5.8 6.6 0.2 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Sm_multidrug_ex PF06695.11 KIR64402.1 - 0.23 12.1 3.3 0.33 11.6 0.3 2.5 2 1 1 3 3 3 0 Putative small multi-drug export protein LapA_dom PF06305.11 KIR64402.1 - 0.46 10.3 9.5 0.38 10.6 0.4 3.1 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain Ribonuclease_P PF00825.18 KIR64403.1 - 1.2e-23 83.3 0.1 1.4e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease P Ribosomal_L34 PF00468.17 KIR64404.1 - 4.1e-21 74.7 11.7 4.4e-21 74.6 11.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Bac_DnaA PF00308.18 KIR64405.1 - 8.7e-99 329.8 0.1 1.4e-98 329.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 KIR64405.1 - 5.5e-30 103.2 0.0 1e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 KIR64405.1 - 3.5e-13 49.7 0.0 6.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 KIR64405.1 - 6.2e-07 29.9 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIR64405.1 - 0.00023 21.2 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaA_N PF11638.8 KIR64405.1 - 0.00024 20.8 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 DnaA N-terminal domain ATPase_2 PF01637.18 KIR64405.1 - 0.0029 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIR64405.1 - 0.0043 17.4 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIR64405.1 - 0.0099 16.2 2.7 3.9 7.7 0.5 2.6 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIR64405.1 - 0.017 15.5 0.3 0.079 13.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIR64405.1 - 0.044 13.5 0.1 0.14 11.9 0.0 1.7 1 1 1 2 2 2 0 AAA domain Microtub_bd PF16796.5 KIR64405.1 - 0.057 13.4 0.6 22 4.9 0.4 3.2 3 0 0 3 3 3 0 Microtubule binding AAA_23 PF13476.6 KIR64405.1 - 0.14 12.7 0.2 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain DNA_pol3_beta PF00712.19 KIR64406.1 - 4.2e-41 139.9 0.0 2.6e-34 117.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 KIR64406.1 - 1.2e-31 109.3 0.0 2.7e-27 95.3 0.0 2.5 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 KIR64406.1 - 2.2e-28 98.5 0.0 1.2e-24 86.5 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase III beta subunit, C-terminal domain NAD_binding_2 PF03446.15 KIR64407.1 - 4.1e-34 118.0 0.2 9.8e-34 116.8 0.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 KIR64407.1 - 5.2e-23 81.8 0.0 6.8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KIR64407.1 - 3.1e-05 23.4 0.0 5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIR64407.1 - 0.0003 21.3 0.1 0.0011 19.4 0.1 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIR64407.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIR64407.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KIR64407.1 - 0.16 11.6 0.2 0.7 9.5 0.2 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SMC_N PF02463.19 KIR64408.1 - 1e-17 64.3 0.0 1.8e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR64408.1 - 2.4e-08 34.7 0.0 3.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KIR64408.1 - 6e-07 29.5 0.0 7.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIR64408.1 - 9.2e-07 29.0 0.0 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR64408.1 - 0.00089 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 KIR64408.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_16 PF13191.6 KIR64408.1 - 0.0018 18.7 0.8 0.37 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Unstab_antitox PF09720.10 KIR64408.1 - 0.087 12.9 0.1 0.41 10.7 0.1 2.3 1 0 0 1 1 1 0 Putative addiction module component AAA_28 PF13521.6 KIR64408.1 - 0.089 13.0 1.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR64408.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIR64408.1 - 0.14 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DciA PF05258.12 KIR64409.1 - 3.8e-25 88.1 0.7 6.3e-25 87.4 0.7 1.4 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA DNA_gyraseB PF00204.25 KIR64411.1 - 6.5e-59 198.3 0.2 1e-58 197.6 0.2 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 KIR64411.1 - 1.8e-27 95.3 0.0 3.4e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 KIR64411.1 - 1.7e-19 70.4 0.0 3.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIR64411.1 - 2.2e-16 59.9 0.0 4.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF3566 PF12089.8 KIR64412.1 - 5.9e-42 142.8 7.3 7.7e-42 142.4 7.3 1.1 1 0 0 1 1 1 1 Transmembrane domain of unknown function (DUF3566) Abhydrolase_1 PF00561.20 KIR64413.1 - 1.6e-19 70.6 0.0 5.4e-19 68.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIR64413.1 - 7.4e-19 67.8 1.0 1.2e-18 67.1 0.2 1.8 2 0 0 2 2 2 1 TAP-like protein HAD_2 PF13419.6 KIR64414.1 - 1.8e-13 51.0 0.0 2.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR64414.1 - 2.5e-12 46.7 0.6 4.8e-12 45.8 0.1 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KIR64414.1 - 7.7e-11 42.7 0.0 9.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64414.1 - 3.9e-07 30.7 0.3 5.2e-07 30.3 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HTH_3 PF01381.22 KIR64414.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix E1-E2_ATPase PF00122.20 KIR64415.1 - 6.9e-41 139.7 2.0 1.5e-40 138.7 2.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIR64415.1 - 6.4e-19 69.1 10.3 6.4e-19 69.1 10.3 3.6 3 2 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIR64415.1 - 1.2e-17 64.3 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KIR64415.1 - 6.9e-05 22.5 0.0 0.0002 21.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HMA PF00403.26 KIR64415.1 - 0.00021 21.7 0.0 0.00068 20.0 0.0 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Cation_ATPase PF13246.6 KIR64415.1 - 0.00044 20.3 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIR64415.1 - 0.0049 16.6 0.2 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64415.1 - 0.021 15.2 0.9 0.087 13.2 0.7 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rz1 PF06085.11 KIR64415.1 - 0.21 11.3 0.6 0.52 10.1 0.6 1.6 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor MFS_1 PF07690.16 KIR64417.1 - 4.9e-18 65.2 77.5 2.3e-14 53.1 51.0 3.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2306 PF10067.9 KIR64417.1 - 4.9 7.4 16.2 0.39 10.9 5.6 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2306) tRNA_edit PF04073.15 KIR64419.1 - 3.2e-17 62.8 0.1 4.4e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DSBA PF01323.20 KIR64420.1 - 2.1e-43 148.3 0.0 2.4e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KIR64420.1 - 8.1e-10 39.1 0.0 5.7e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.6 KIR64420.1 - 2.1e-07 30.8 0.0 3.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 KIR64420.1 - 0.00088 19.3 0.0 0.032 14.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KIR64420.1 - 0.0035 17.8 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain SufE PF02657.15 KIR64421.1 - 6.4e-22 77.7 0.0 7.2e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain CBS PF00571.28 KIR64422.1 - 1.6e-24 86.1 5.4 7.9e-12 45.4 0.1 2.1 2 0 0 2 2 2 2 CBS domain tRNA-synt_2b PF00587.25 KIR64423.1 - 1.2e-36 126.4 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 KIR64423.1 - 3.6e-16 59.4 0.1 6.7e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 KIR64423.1 - 8.7e-14 51.4 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Lipase_GDSL_2 PF13472.6 KIR64424.1 - 2.1e-25 90.1 0.9 3.3e-25 89.5 0.9 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR64424.1 - 3.6e-13 49.9 0.0 4.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.20 KIR64426.1 - 3.4e-33 114.4 0.1 1.4e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Mating_C PF12737.7 KIR64426.1 - 0.6 9.3 1.2 11 5.1 0.3 2.1 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 DUF2905 PF11146.8 KIR64427.1 - 0.89 9.8 12.8 5.7 7.2 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2905) Phage_holin_3_6 PF07332.11 KIR64427.1 - 9.7 6.3 20.6 1.8 8.6 8.3 2.3 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HATPase_c_3 PF13589.6 KIR64428.1 - 2.9e-09 36.9 0.0 4.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIR64428.1 - 7.8e-06 26.4 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.18 KIR64428.1 - 0.00023 20.2 0.0 0.00032 19.7 0.0 1.1 1 0 0 1 1 1 1 Hsp90 protein TPR_12 PF13424.6 KIR64429.1 - 3.4e-09 36.8 62.8 0.00015 22.0 1.4 9.4 8 3 2 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIR64429.1 - 3.4e-05 23.7 6.9 27 5.3 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIR64429.1 - 8.3e-05 22.7 1.2 0.17 12.1 0.3 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KIR64429.1 - 0.00042 20.9 1.8 0.00042 20.9 1.8 12.8 9 3 2 13 13 13 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIR64429.1 - 0.0015 18.5 38.5 0.13 12.4 1.1 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat HTH_15 PF12324.8 KIR64429.1 - 0.022 14.7 0.7 0.33 10.9 0.2 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase TPR_7 PF13176.6 KIR64429.1 - 0.027 14.5 21.4 6 7.1 0.3 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIR64429.1 - 1.4 8.9 64.5 0.091 12.7 1.3 12.2 13 0 0 13 13 13 0 Tetratricopeptide repeat TetR_N PF00440.23 KIR64430.1 - 1.3e-17 63.3 1.0 1.3e-17 63.3 1.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KIR64430.1 - 1.7e-08 34.7 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 KIR64430.1 - 0.0021 18.8 5.7 0.0033 18.1 5.7 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_17 PF12728.7 KIR64431.1 - 0.027 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2750 PF11042.8 KIR64431.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) DUF397 PF04149.12 KIR64432.1 - 3.8e-22 78.1 0.1 4.2e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) CPSase_L_D2 PF02786.17 KIR64433.1 - 1.4e-66 224.1 0.1 2.1e-66 223.4 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIR64433.1 - 1.1e-42 145.1 0.1 2.1e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIR64433.1 - 1.9e-35 121.2 0.0 3.4e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KIR64433.1 - 8.5e-09 35.2 0.0 1.6e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KIR64433.1 - 3.5e-05 23.3 0.0 0.00037 20.0 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 KIR64433.1 - 0.0038 16.8 0.0 0.0092 15.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain LAL_C2 PF18603.1 KIR64433.1 - 0.023 14.8 0.1 0.094 12.9 0.1 2.1 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 AP_endonuc_2 PF01261.24 KIR64433.1 - 0.099 12.1 0.7 0.52 9.7 0.1 2.3 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Peptidase_M7 PF02031.16 KIR64434.1 - 5.2e-33 114.0 2.6 7.5e-33 113.5 2.6 1.2 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.8 KIR64434.1 - 0.00016 21.3 5.2 0.00025 20.7 5.1 1.3 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.13 KIR64434.1 - 0.00093 19.1 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIR64434.1 - 0.0032 17.6 0.4 0.0043 17.2 0.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 KIR64434.1 - 0.0032 16.7 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 KIR64434.1 - 0.025 14.2 0.4 0.038 13.6 0.4 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M6 PF05547.11 KIR64434.1 - 0.027 12.8 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Astacin PF01400.24 KIR64434.1 - 0.028 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KIR64434.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.3 1 1 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.11 KIR64434.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Carboxyl_trans PF01039.22 KIR64435.1 - 4.5e-150 500.5 1.5 5.1e-150 500.4 1.5 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KIR64435.1 - 0.0017 17.9 3.0 0.013 15.0 1.4 2.4 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 KIR64436.1 - 2.4e-50 170.7 3.1 3.6e-50 170.1 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR64436.1 - 6.7e-39 133.0 0.1 1.3e-38 132.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIR64436.1 - 1.2e-21 77.4 1.7 1.8e-21 76.8 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR64436.1 - 2.4e-21 75.7 0.3 4.4e-21 74.9 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HTH_31 PF13560.6 KIR64437.1 - 9.3e-12 45.1 9.4 9.3e-12 45.1 9.4 6.7 6 1 0 6 6 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64437.1 - 6.4e-09 35.7 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix AAA_16 PF13191.6 KIR64437.1 - 9.5e-07 29.3 1.5 9.5e-07 29.3 1.5 3.9 4 1 0 4 4 4 1 AAA ATPase domain TPR_12 PF13424.6 KIR64437.1 - 4.4e-05 23.7 0.5 4.4e-05 23.7 0.5 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_5 PF07728.14 KIR64437.1 - 0.0002 21.3 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIR64437.1 - 0.0003 20.4 2.1 0.0003 20.4 2.1 2.5 2 0 0 2 2 2 1 AAA domain HTH_25 PF13413.6 KIR64437.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain NB-ARC PF00931.22 KIR64437.1 - 0.0027 16.9 0.0 0.0083 15.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain HTH_19 PF12844.7 KIR64437.1 - 0.044 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_21 PF09976.9 KIR64437.1 - 0.049 13.3 5.7 0.068 12.9 4.6 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Sigma70_r4 PF04545.16 KIR64437.1 - 0.073 12.6 0.1 0.26 10.8 0.1 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 NACHT PF05729.12 KIR64437.1 - 0.13 12.1 0.3 0.53 10.2 0.3 2.0 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 KIR64437.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.6 KIR64437.1 - 0.36 10.8 6.6 21 5.2 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat MarR_2 PF12802.7 KIR64438.1 - 6.4e-15 54.8 0.6 1.1e-14 54.0 0.6 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KIR64438.1 - 1.1e-13 50.8 0.1 1.8e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR64438.1 - 1.1e-06 29.1 0.0 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 KIR64438.1 - 6.8e-05 22.4 0.0 0.00017 21.1 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR64438.1 - 0.00013 21.7 0.3 0.00029 20.6 0.3 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 KIR64438.1 - 0.002 18.4 0.0 0.0075 16.6 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator GntR PF00392.21 KIR64438.1 - 0.0053 16.4 0.2 0.011 15.3 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 KIR64438.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KIR64438.1 - 0.012 15.6 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_29 PF13551.6 KIR64438.1 - 0.089 12.8 0.1 1.6 8.8 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn helix AbiEi_4 PF13338.6 KIR64438.1 - 0.1 12.8 0.3 1.2 9.4 0.1 2.6 1 1 2 3 3 3 0 Transcriptional regulator, AbiEi antitoxin YceI PF04264.13 KIR64439.1 - 1.3e-45 155.5 0.1 1.7e-45 155.2 0.1 1.0 1 0 0 1 1 1 1 YceI-like domain GCS2 PF04107.13 KIR64440.1 - 5.1e-06 26.0 0.0 0.00084 18.8 0.0 2.4 2 0 0 2 2 2 2 Glutamate-cysteine ligase family 2(GCS2) PASTA PF03793.19 KIR64441.1 - 7.7e-16 57.7 0.0 9e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 PASTA domain PASTA PF03793.19 KIR64442.1 - 5.9e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 PASTA domain Cyt_c_ox_IV PF12270.8 KIR64442.1 - 1.7 8.8 3.2 8.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV SWIRM-assoc_2 PF16496.5 KIR64443.1 - 0.037 12.9 0.0 0.039 12.8 0.0 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal HTH_31 PF13560.6 KIR64444.1 - 3.1e-15 56.2 1.0 3.1e-15 56.2 1.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR64444.1 - 3e-07 30.4 0.1 1e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64444.1 - 1.1e-06 28.6 0.1 7.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_25 PF13413.6 KIR64444.1 - 7e-05 22.6 0.6 0.00031 20.5 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma54_DBD PF04552.13 KIR64444.1 - 0.024 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HTH_37 PF13744.6 KIR64444.1 - 0.039 13.9 0.4 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2316 PF10078.9 KIR64444.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF397 PF04149.12 KIR64445.1 - 4.3e-22 77.9 0.6 5.3e-22 77.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) DUF3662 PF12401.8 KIR64448.1 - 6.2e-39 132.9 0.0 8.3e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2662) Yop-YscD_cpl PF16697.5 KIR64448.1 - 1.6e-20 73.2 0.0 2.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KIR64448.1 - 9.2e-20 70.8 0.1 1.5e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIR64449.1 - 3.9e-15 55.9 0.0 5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KIR64449.1 - 3.2e-14 53.0 0.0 4.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain PP2C_2 PF13672.6 KIR64450.1 - 2.4e-13 50.2 0.4 4.5e-13 49.3 0.4 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KIR64450.1 - 1.9e-12 47.4 0.0 2.5e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C BofC_C PF08955.10 KIR64450.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 BofC C-terminal domain FTSW_RODA_SPOVE PF01098.19 KIR64451.1 - 1.1e-70 238.5 14.2 1.5e-70 238.0 14.2 1.2 1 0 0 1 1 1 1 Cell cycle protein Phage_holin_2_1 PF04971.12 KIR64451.1 - 0.11 12.5 0.3 0.49 10.4 0.3 2.1 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF3522 PF12036.8 KIR64451.1 - 0.44 10.8 3.4 0.34 11.2 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) Transpeptidase PF00905.22 KIR64452.1 - 6.1e-58 196.4 0.0 7.8e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Pkinase PF00069.25 KIR64453.1 - 1.7e-42 145.6 0.0 2.1e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR64453.1 - 1.6e-30 106.3 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR64453.1 - 1.2e-06 28.6 1.7 0.00078 19.4 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KIR64453.1 - 0.0072 15.7 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIR64453.1 - 0.0098 15.3 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3040 PF11239.8 KIR64453.1 - 0.059 13.7 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RIO1 PF01163.22 KIR64453.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIR64453.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fructosamin_kin PF03881.14 KIR64453.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 KIR64454.1 - 3.5e-48 164.3 0.0 4.8e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PASTA PF03793.19 KIR64454.1 - 1.1e-33 114.8 15.8 6.9e-12 45.0 1.0 3.4 3 0 0 3 3 3 3 PASTA domain Pkinase_Tyr PF07714.17 KIR64454.1 - 2e-32 112.5 0.0 2.7e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR64454.1 - 1.1e-07 32.1 0.2 0.00024 21.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR64454.1 - 0.00075 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIR64454.1 - 0.2 10.6 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RNase_II_C_S1 PF18614.1 KIR64454.1 - 0.31 11.0 2.7 3.5 7.6 0.0 3.5 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain PepSY_2 PF13670.6 KIR64454.1 - 0.64 10.1 5.1 8.4 6.5 2.5 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain GATase PF00117.28 KIR64455.1 - 6.3e-53 179.4 0.0 7.4e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIR64455.1 - 1.1e-08 35.1 0.1 3.3e-08 33.6 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 Sortase PF04203.13 KIR64457.1 - 7.3e-34 116.3 0.0 1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Sortase domain DUF881 PF05949.12 KIR64458.1 - 5.6e-38 130.1 0.1 8.6e-38 129.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) DASH_Spc19 PF08287.11 KIR64458.1 - 0.024 14.5 0.3 0.035 14.0 0.3 1.2 1 0 0 1 1 1 0 Spc19 CrgA PF06781.12 KIR64459.1 - 1.7e-29 101.7 0.9 1.9e-29 101.6 0.9 1.0 1 0 0 1 1 1 1 Cell division protein CrgA DUF3040 PF11239.8 KIR64459.1 - 0.0029 17.8 0.4 0.0037 17.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) FixP_N PF14715.6 KIR64459.1 - 0.016 14.9 0.4 0.016 14.9 0.4 1.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF308 PF03729.13 KIR64459.1 - 0.027 14.8 2.9 0.034 14.5 2.9 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF3341 PF11821.8 KIR64459.1 - 0.068 12.8 0.2 0.07 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) CCG PF02754.16 KIR64460.1 - 6.6e-36 122.4 0.8 5e-17 61.9 0.1 2.7 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 KIR64460.1 - 3.4e-14 53.0 1.7 7.4e-14 51.9 0.5 2.2 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR64460.1 - 1e-11 44.7 9.3 4.9e-11 42.6 5.8 3.0 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIR64460.1 - 2.2e-10 40.5 1.8 2.2e-10 40.5 1.8 2.2 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR64460.1 - 2e-08 34.7 3.1 0.0032 18.0 0.2 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KIR64460.1 - 1.1e-07 32.2 2.2 0.018 15.6 0.1 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KIR64460.1 - 1.5e-06 27.7 12.5 0.0082 15.9 5.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KIR64460.1 - 3.9e-06 27.7 3.6 0.065 14.2 0.5 2.7 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KIR64460.1 - 0.00068 19.6 18.5 0.0013 18.7 1.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KIR64460.1 - 0.0046 17.8 17.0 0.032 15.2 5.1 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KIR64460.1 - 0.006 17.3 1.4 3.3 8.5 0.3 2.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_4 PF12800.7 KIR64460.1 - 0.009 16.5 19.4 0.1 13.1 3.2 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain RNA_pol_Rpb1_1 PF04997.12 KIR64460.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Fer4_21 PF14697.6 KIR64460.1 - 0.22 11.7 12.9 1.5 9.0 2.7 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KIR64460.1 - 0.36 11.7 14.1 0.24 12.3 0.3 3.6 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KIR64460.1 - 2.5 8.3 7.6 4.5 7.5 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR64460.1 - 2.7 8.2 18.8 0.92 9.7 1.5 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain DUF21 PF01595.20 KIR64461.1 - 9.8e-35 119.8 3.8 1.3e-34 119.4 3.8 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIR64461.1 - 1.5e-12 47.7 0.9 2.2e-07 31.2 0.4 2.5 2 0 0 2 2 2 2 CBS domain NLPC_P60 PF00877.19 KIR64462.1 - 5.6e-23 81.0 0.0 1.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family DUF948 PF06103.11 KIR64462.1 - 0.0016 18.6 1.2 0.047 14.0 0.0 2.8 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 KIR64462.1 - 0.0031 17.7 7.7 0.43 10.8 5.5 2.7 2 1 0 2 2 2 1 JNK_SAPK-associated protein-1 Peptidase_C92 PF05708.12 KIR64462.1 - 0.0082 16.3 0.6 0.26 11.3 0.0 2.9 2 1 1 3 3 3 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PI3K_P85_iSH2 PF16454.5 KIR64462.1 - 0.0094 15.6 3.5 1.7 8.2 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MLP1_2 PF07926.12 KIR64462.1 - 0.015 15.4 9.1 0.21 11.7 3.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 KIR64462.1 - 0.017 15.5 2.3 0.046 14.0 1.9 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4446 PF14584.6 KIR64462.1 - 0.021 14.8 0.0 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Laminin_I PF06008.14 KIR64462.1 - 0.025 14.3 0.5 0.025 14.3 0.5 1.9 1 1 1 2 2 2 0 Laminin Domain I Phage_GPO PF05929.11 KIR64462.1 - 0.043 13.4 1.0 0.45 10.1 0.1 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Mod_r PF07200.13 KIR64462.1 - 0.061 13.4 5.0 7.1 6.7 3.4 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Amidase_5 PF05382.13 KIR64462.1 - 0.096 12.6 0.2 0.38 10.6 0.2 1.9 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase BLOC1_2 PF10046.9 KIR64462.1 - 0.11 12.9 3.0 7.7 6.9 1.1 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KIR64462.1 - 0.15 12.8 4.3 0.73 10.6 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ADIP PF11559.8 KIR64462.1 - 0.16 12.1 6.6 0.98 9.5 2.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding LRAT PF04970.13 KIR64462.1 - 0.16 12.2 0.4 0.41 11.0 0.1 1.8 2 0 0 2 2 1 0 Lecithin retinol acyltransferase GPHR_N PF12537.8 KIR64462.1 - 0.18 11.9 0.1 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal COG2 PF06148.11 KIR64462.1 - 0.19 11.8 2.7 1.3 9.1 0.8 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cluap1 PF10234.9 KIR64462.1 - 0.24 10.8 3.8 1.6 8.1 1.9 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4407 PF14362.6 KIR64462.1 - 0.25 10.7 11.6 0.8 9.0 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 KIR64462.1 - 0.26 10.7 7.8 2.3 7.6 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) FlxA PF14282.6 KIR64462.1 - 0.27 11.3 8.5 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 FlxA-like protein TBCC_N PF16752.5 KIR64462.1 - 0.35 11.3 3.6 19 5.8 2.1 2.2 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DHR10 PF18595.1 KIR64462.1 - 0.41 10.7 13.6 1.6 8.8 6.6 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 KIR64462.1 - 0.47 10.5 2.4 5.3 7.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KIR64462.1 - 0.74 9.4 3.3 17 5.0 1.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region Baculo_PEP_C PF04513.12 KIR64462.1 - 0.93 9.5 3.1 12 5.9 2.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mce4_CUP1 PF11887.8 KIR64462.1 - 0.94 8.9 4.0 16 4.8 1.1 2.4 2 1 1 3 3 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF3040 PF11239.8 KIR64462.1 - 0.95 9.8 4.3 5.7 7.3 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) HemX PF04375.14 KIR64462.1 - 0.96 8.7 10.0 2.1 7.5 0.1 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc24 PF08286.11 KIR64462.1 - 0.97 9.7 2.6 1.5 9.1 0.5 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 kleA_kleC PF17383.2 KIR64462.1 - 1 9.8 8.1 3.2 8.1 0.4 3.4 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A DivIC PF04977.15 KIR64462.1 - 1.4 8.8 11.3 2.2 8.1 3.7 2.7 2 1 0 2 2 2 0 Septum formation initiator Cortex-I_coil PF09304.10 KIR64462.1 - 3.6 7.8 7.3 27 5.0 0.1 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil AAA_13 PF13166.6 KIR64462.1 - 3.7 6.1 6.6 41 2.6 6.6 1.9 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.11 KIR64462.1 - 4 6.2 10.7 1.7 7.4 5.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KIR64462.1 - 4.9 7.3 12.3 1.5 9.0 6.1 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 KIR64462.1 - 6.4 7.2 9.4 9.1 6.7 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HOOK PF05622.12 KIR64462.1 - 9 4.3 11.5 0.45 8.6 3.9 2.2 2 1 1 3 3 3 0 HOOK protein APG6_N PF17675.1 KIR64462.1 - 9.5 6.8 8.7 11 6.5 3.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DCD PF06559.11 KIR64463.1 - 2.9e-12 46.1 0.0 4.1e-07 29.1 0.0 2.1 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) dUTPase PF00692.19 KIR64463.1 - 2e-10 40.4 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase Putative_PNPOx PF01243.20 KIR64464.1 - 2.2e-05 24.6 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M43 PF05572.13 KIR64465.1 - 9.5e-18 64.6 0.4 1.7e-17 63.8 0.1 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KIR64465.1 - 0.00023 21.7 0.9 0.1 13.1 0.3 2.9 2 1 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KIR64465.1 - 0.0098 16.1 4.3 0.073 13.2 4.2 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KIR64465.1 - 0.23 11.1 3.2 0.97 9.0 1.8 2.4 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Phage_integrase PF00589.22 KIR64466.1 - 6.3e-18 65.2 0.0 1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KIR64466.1 - 2.4e-07 30.9 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 KIR64466.1 - 0.0088 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Phage integrase SAM-like domain LZ_Tnp_IS66 PF13007.7 KIR64467.1 - 2.5 9.0 7.4 0.21 12.4 1.8 2.2 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Glycos_transf_2 PF00535.26 KIR64472.1 - 3.4e-10 40.0 0.0 7.5e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR64472.1 - 1.5e-05 25.0 0.0 3.2e-05 23.9 0.0 1.5 1 1 0 2 2 2 1 Glycosyltransferase like family 2 UTRA PF07702.13 KIR64473.1 - 5.3e-21 75.0 0.2 1.1e-20 73.9 0.2 1.5 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 KIR64473.1 - 2.1e-20 72.1 1.7 2.1e-20 72.1 0.5 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 KIR64473.1 - 3.1e-05 23.8 0.1 8.8e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 KIR64473.1 - 0.00014 21.6 0.1 0.00026 20.7 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR64473.1 - 0.00015 21.7 0.1 0.00029 20.8 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 KIR64473.1 - 0.00031 20.5 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KIR64473.1 - 0.0014 18.4 0.3 0.0039 17.1 0.3 1.8 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KIR64473.1 - 0.0052 17.1 0.0 0.0096 16.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 KIR64473.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KIR64473.1 - 0.018 15.1 0.2 0.047 13.7 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_20 PF12840.7 KIR64473.1 - 0.027 14.5 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 KIR64473.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 KIR64473.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Methyltransf_20 PF12147.8 KIR64476.1 - 1.3e-05 24.6 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIR64476.1 - 5.4e-05 23.8 0.3 8.2e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR64476.1 - 0.0037 18.0 0.0 0.0052 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR64476.1 - 0.04 13.7 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain DoxX_2 PF13564.6 KIR64477.1 - 2.5e-20 72.5 15.3 3e-20 72.3 15.3 1.0 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 KIR64477.1 - 0.3 11.7 18.2 0.85 10.3 17.9 1.9 1 1 0 1 1 1 0 DoxX Bac_luciferase PF00296.20 KIR64478.1 - 2.7e-48 165.0 6.4 2.7e-48 165.0 6.4 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase ASCH PF04266.14 KIR64479.1 - 6.1e-16 58.9 0.0 7.2e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 ASCH domain Questin_oxidase PF14027.6 KIR64481.1 - 1.1e-23 84.4 0.0 3e-23 82.9 0.0 1.6 1 1 0 1 1 1 1 Questin oxidase-like Cuticle_3 PF11018.8 KIR64481.1 - 1.1 9.5 11.1 1.6 9.0 11.1 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 DPBB_1 PF03330.18 KIR64482.1 - 8.4e-26 90.1 0.0 1.7e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIR64482.1 - 0.0073 16.1 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Barwin family SOG2 PF10428.9 KIR64482.1 - 0.79 8.9 6.6 0.8 8.8 6.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDC27 PF09507.10 KIR64482.1 - 10 5.4 8.5 12 5.1 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SpoIIE PF07228.12 KIR64483.1 - 3.6e-34 118.4 0.8 5.3e-34 117.8 0.1 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIR64483.1 - 0.055 13.1 0.1 0.055 13.1 0.1 2.4 2 1 0 2 2 2 0 Protein phosphatase 2C 7TM-7TMR_HD PF07698.11 KIR64483.1 - 1.3 8.7 6.0 2.1 8.1 6.0 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Acyl-CoA_dh_C PF12806.7 KIR64484.1 - 6e-30 104.0 0.3 6e-30 104.0 0.3 1.8 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 KIR64484.1 - 5e-17 61.9 0.0 9.2e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KIR64484.1 - 6.1e-14 52.5 4.5 3.2e-13 50.2 1.4 3.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 KIR64484.1 - 9.1e-10 38.4 1.8 9.6e-10 38.3 0.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 KIR64484.1 - 0.017 15.4 0.0 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain PMP22_Claudin PF00822.20 KIR64485.1 - 0.051 13.4 0.7 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.9 KIR64485.1 - 0.073 11.8 0.4 0.079 11.7 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 KIR64485.1 - 0.16 12.5 5.9 0.29 11.6 5.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) CAP_N PF01213.19 KIR64485.1 - 0.62 9.5 3.2 0.73 9.2 3.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4381 PF14316.6 KIR64485.1 - 1.7 8.9 8.5 0.56 10.4 6.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DUF4131 PF13567.6 KIR64485.1 - 2.7 7.6 9.2 0.17 11.5 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3953 PF13129.6 KIR64485.1 - 8.1 6.3 10.4 1.1 9.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF3394 PF11874.8 KIR64485.1 - 9.8 5.8 6.6 5.2 6.7 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) His_Phos_1 PF00300.22 KIR64486.1 - 5.4e-08 32.7 2.1 8.3e-07 28.9 0.7 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4131 PF13567.6 KIR64487.1 - 0.04 13.6 1.3 0.049 13.3 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4231 PF14015.6 KIR64487.1 - 0.19 12.2 2.2 0.25 11.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 KIR64487.1 - 0.39 9.4 1.0 0.39 9.4 1.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HlyIII PF03006.20 KIR64488.1 - 8.5e-42 143.4 13.6 9.6e-42 143.2 13.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related Tim17 PF02466.19 KIR64488.1 - 0.0057 17.0 1.2 0.015 15.6 0.2 2.0 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4203 PF13886.6 KIR64488.1 - 2 8.0 24.9 0.11 12.2 10.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) CT_A_B PF02626.15 KIR64489.1 - 8.8e-87 291.1 1.1 1.7e-86 290.1 1.1 1.4 1 1 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B LamB_YcsF PF03746.16 KIR64490.1 - 4.2e-95 318.0 0.0 4.8e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family NHL PF01436.21 KIR64491.1 - 1.3e-23 81.7 1.6 4.3e-05 23.3 0.0 7.4 7 0 0 7 7 7 6 NHL repeat AhpC-TSA PF00578.21 KIR64491.1 - 2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KIR64491.1 - 4e-07 30.3 0.0 8.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KIR64491.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin SGL PF08450.12 KIR64491.1 - 0.011 15.4 0.0 0.17 11.5 0.0 2.7 2 2 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIR64491.1 - 0.02 15.0 0.0 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 Strictosidine synthase Thioredoxin_2 PF13098.6 KIR64491.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain GSDH PF07995.11 KIR64491.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Transket_pyr PF02779.24 KIR64493.1 - 1.3e-44 152.0 0.0 1.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIR64493.1 - 4.2e-37 126.8 0.0 8e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 KIR64494.1 - 3e-69 233.3 0.0 3.6e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KIR64494.1 - 0.00034 20.4 0.1 0.0089 15.8 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KIR64494.1 - 0.015 14.5 0.0 0.033 13.4 0.0 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Dynamin_N PF00350.23 KIR64496.1 - 2.8e-07 30.8 0.2 0.005 16.9 0.1 2.2 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KIR64496.1 - 3.3e-06 27.2 0.0 7.9e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR64496.1 - 0.00058 19.8 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KIR64496.1 - 0.0013 18.2 0.1 0.57 9.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 KIR64496.1 - 0.0016 18.9 0.4 0.011 16.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KIR64496.1 - 0.0033 17.9 0.0 0.0066 17.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIR64496.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR64496.1 - 0.008 16.4 0.3 3.6 7.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIR64496.1 - 0.056 13.9 0.0 0.088 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIR64496.1 - 0.056 13.7 0.3 0.82 9.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIR64496.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIR64496.1 - 0.13 11.6 0.1 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KIR64496.1 - 0.13 12.2 1.0 7.1 6.5 0.0 2.7 3 0 0 3 3 3 0 NACHT domain SMC_N PF02463.19 KIR64496.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIR64496.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 KIR64497.1 - 3.4e-07 30.5 0.2 0.00012 22.2 0.3 2.2 1 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KIR64497.1 - 0.00076 19.5 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KIR64497.1 - 0.001 18.4 1.5 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 KIR64497.1 - 0.0025 17.8 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 KIR64497.1 - 0.034 13.8 0.4 0.069 12.7 0.4 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KIR64497.1 - 0.035 14.5 0.4 0.035 14.5 0.4 3.6 3 2 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 KIR64497.1 - 0.049 12.7 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KIR64497.1 - 0.049 14.1 0.0 0.082 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KIR64497.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIR64497.1 - 0.057 13.6 0.4 0.32 11.2 0.4 2.1 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KIR64497.1 - 0.068 12.4 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Septin DUF87 PF01935.17 KIR64497.1 - 0.077 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KIR64497.1 - 0.15 12.3 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Gas_vesicle_C PF01304.17 KIR64497.1 - 5.6 7.1 5.4 29 4.8 0.2 2.8 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain HSP70 PF00012.20 KIR64498.1 - 1.8e-243 809.2 8.0 2e-214 713.3 2.5 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KIR64498.1 - 4.1e-17 62.0 1.8 2e-16 59.7 1.8 2.1 1 1 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 KIR64498.1 - 0.0026 17.0 0.0 0.68 9.1 0.0 2.6 3 0 0 3 3 3 2 StbA protein FtsA PF14450.6 KIR64498.1 - 0.0087 16.5 1.8 0.95 9.9 0.3 3.6 2 1 0 2 2 2 1 Cell division protein FtsA GrpE PF01025.19 KIR64499.1 - 1.4e-34 119.2 0.0 2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 GrpE DnaJ_C PF01556.18 KIR64500.1 - 1.6e-35 122.3 0.0 2.3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIR64500.1 - 2.7e-25 88.3 0.4 3.9e-25 87.8 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIR64500.1 - 3.5e-12 46.5 16.3 6.1e-12 45.7 16.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIR64500.1 - 0.0046 16.9 18.5 0.23 11.4 4.7 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_CBB3 PF13442.6 KIR64500.1 - 0.032 14.5 3.3 2.4 8.5 0.0 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf_Rg PF17915.1 KIR64500.1 - 2.3 7.7 4.5 2.4 7.6 0.2 2.5 1 1 1 2 2 2 0 Reverse gyrase zinc finger Cytochrom_c3_2 PF14537.6 KIR64500.1 - 3.6 8.1 6.1 32 5.1 4.6 2.3 1 1 0 1 1 1 0 Cytochrome c3 A2L_zn_ribbon PF08792.10 KIR64500.1 - 6.5 6.6 6.6 0.99 9.2 1.7 2.2 2 1 0 2 2 2 0 A2L zinc ribbon domain DUF5351 PF17302.2 KIR64500.1 - 7 6.9 19.1 11 6.3 0.1 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5351) MerR_1 PF13411.6 KIR64501.1 - 3.1e-14 52.8 0.0 4.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR64501.1 - 7.1e-10 38.5 0.1 1.6e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 MerR family regulatory protein MerR_2 PF13591.6 KIR64501.1 - 0.00098 18.9 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein ABC_tran_CTD PF16326.5 KIR64501.1 - 0.026 14.7 1.3 0.044 14.0 1.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain SlyX PF04102.12 KIR64501.1 - 0.044 14.4 0.1 0.086 13.5 0.1 1.5 1 0 0 1 1 1 0 SlyX MT0933_antitox PF14013.6 KIR64502.1 - 0.031 14.6 1.0 0.059 13.7 0.1 1.8 2 0 0 2 2 2 0 MT0933-like antitoxin protein Na_H_Exchanger PF00999.21 KIR64504.1 - 1.2e-50 172.4 44.2 1.5e-50 172.1 44.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_C PF02080.21 KIR64505.1 - 1.7e-15 56.6 0.2 3.3e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 TrkA-C domain Cupin_3 PF05899.12 KIR64505.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) BNR PF02012.20 KIR64506.1 - 3.6e-06 26.2 4.9 0.6 10.3 0.1 3.6 3 0 0 3 3 3 3 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KIR64506.1 - 0.0072 15.2 0.0 0.41 9.4 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, AAA_2 PF07724.14 KIR64507.1 - 1e-54 185.2 0.1 2.4e-53 180.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIR64507.1 - 5.3e-35 119.5 0.5 5.3e-35 119.5 0.5 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KIR64507.1 - 8.3e-27 93.1 0.2 3.6e-26 91.0 0.2 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIR64507.1 - 3.3e-23 82.6 0.0 2.1e-11 44.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KIR64507.1 - 1.2e-22 79.7 9.9 3.7e-12 46.2 0.9 4.2 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KIR64507.1 - 1.7e-18 67.0 0.1 3.3e-12 46.6 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIR64507.1 - 2.2e-09 37.9 2.7 1.7e-05 25.3 0.1 5.0 4 3 1 5 5 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KIR64507.1 - 2.3e-09 37.2 0.0 2.9e-06 27.1 0.0 2.5 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KIR64507.1 - 3e-08 34.0 0.1 0.0079 16.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain TniB PF05621.11 KIR64507.1 - 8.8e-07 28.5 0.0 0.00042 19.8 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KIR64507.1 - 9.8e-07 28.7 0.0 0.047 13.4 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIR64507.1 - 1.2e-05 24.8 0.0 0.25 10.7 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KIR64507.1 - 1.2e-05 25.4 0.1 1 9.3 0.0 3.7 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KIR64507.1 - 5e-05 23.9 0.6 0.57 10.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KIR64507.1 - 6.4e-05 23.0 0.0 0.38 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIR64507.1 - 6.6e-05 22.5 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KIR64507.1 - 9.5e-05 22.6 0.1 0.084 13.0 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KIR64507.1 - 0.00011 22.5 0.3 1.4 9.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KIR64507.1 - 0.00016 22.2 4.6 0.17 12.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain Roc PF08477.13 KIR64507.1 - 0.00048 20.3 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KIR64507.1 - 0.00068 19.4 0.0 0.55 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIR64507.1 - 0.00095 18.9 0.1 1.6 8.5 0.0 3.7 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KIR64507.1 - 0.00097 19.1 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KIR64507.1 - 0.0012 19.2 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 KIR64507.1 - 0.0014 18.7 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KIR64507.1 - 0.0016 18.3 0.0 5 7.0 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KIR64507.1 - 0.0025 17.1 0.8 0.7 9.1 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin RsgA_GTPase PF03193.16 KIR64507.1 - 0.0027 17.6 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KIR64507.1 - 0.01 16.3 0.0 2.1 8.8 0.0 2.8 2 0 0 2 2 2 0 ABC transporter HOOK PF05622.12 KIR64507.1 - 0.011 13.9 6.8 0.016 13.4 6.8 1.1 1 0 0 1 1 1 0 HOOK protein AAA_29 PF13555.6 KIR64507.1 - 0.012 15.4 0.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4407 PF14362.6 KIR64507.1 - 0.014 14.7 5.8 0.026 13.9 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T2SSE PF00437.20 KIR64507.1 - 0.014 14.4 0.0 0.049 12.7 0.0 1.9 1 1 0 1 1 1 0 Type II/IV secretion system protein Mod_r PF07200.13 KIR64507.1 - 0.021 15.0 1.9 0.048 13.8 1.9 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF815 PF05673.13 KIR64507.1 - 0.028 13.6 0.0 3.7 6.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 KIR64507.1 - 0.042 14.2 0.1 2.2 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain DNA_pol3_delta2 PF13177.6 KIR64507.1 - 0.043 13.6 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 KIR64507.1 - 0.062 13.2 0.0 8.1 6.3 0.0 2.7 2 0 0 2 2 2 0 NTPase ResIII PF04851.15 KIR64507.1 - 0.15 12.1 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 KIR64507.1 - 0.15 11.9 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein ATP_bind_1 PF03029.17 KIR64507.1 - 0.19 11.5 0.0 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DivIC PF04977.15 KIR64507.1 - 0.22 11.3 6.9 6.7 6.5 0.0 3.0 2 1 1 3 3 2 0 Septum formation initiator DUF4201 PF13870.6 KIR64507.1 - 0.27 10.9 6.2 4.8 6.9 6.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF87 PF01935.17 KIR64507.1 - 0.32 11.1 1.6 5 7.1 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain FTA4 PF13093.6 KIR64507.1 - 0.48 10.3 2.6 0.92 9.4 2.6 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fez1 PF06818.15 KIR64507.1 - 1.8 9.0 9.8 2.2 8.7 8.0 1.9 1 1 0 1 1 1 0 Fez1 DUF2968 PF11180.8 KIR64507.1 - 4.2 6.9 10.1 1.7 8.2 4.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Csm1_N PF18504.1 KIR64507.1 - 8.6 6.8 6.3 41 4.6 0.1 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain DUF2019 PF09450.10 KIR64508.1 - 0.037 14.0 0.2 0.082 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) DUF4178 PF13785.6 KIR64509.1 - 4e-30 104.8 0.1 4.9e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4178) DUF2617 PF10936.8 KIR64510.1 - 3.8e-49 166.8 0.0 4.4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF2617 DUF4247 PF14042.6 KIR64511.1 - 5.9e-18 65.8 0.0 6.8e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4247) SLATT_1 PF18181.1 KIR64511.1 - 0.89 9.5 2.6 4.2 7.3 0.9 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF350 PF03994.14 KIR64512.1 - 1.4e-32 111.5 13.4 1.7e-16 60.1 4.4 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) DUF4064 PF13273.6 KIR64512.1 - 1.4 9.3 9.0 0.11 12.7 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TctB PF07331.11 KIR64513.1 - 0.049 13.9 0.8 0.43 10.8 0.3 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family CbtB PF09489.10 KIR64513.1 - 0.24 11.5 1.3 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF4381 PF14316.6 KIR64513.1 - 5 7.4 7.0 0.79 10.0 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Spermine_synth PF01564.17 KIR64514.1 - 5e-31 107.6 0.0 8.2e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KIR64514.1 - 3.2e-06 27.8 0.1 2.8e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64514.1 - 0.00019 22.0 0.2 0.0021 18.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KIR64514.1 - 0.00083 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIR64514.1 - 0.012 16.3 0.0 0.027 15.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIR64514.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4751 PF15942.5 KIR64514.1 - 0.23 11.4 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4751) DUF2976 PF11190.8 KIR64516.1 - 0.36 10.7 4.6 3.1 7.7 3.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4064 PF13273.6 KIR64516.1 - 0.51 10.7 10.1 4.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Trp_oprn_chp PF09534.10 KIR64516.1 - 1.6 8.5 11.7 2.5 7.9 11.5 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.25 KIR64518.1 - 2.8e-44 150.9 0.0 3.9e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR64518.1 - 1.3e-29 103.4 0.0 2.2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR64518.1 - 7.5e-11 42.3 0.1 1.1e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR64518.1 - 2.3e-05 24.0 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR64518.1 - 0.0012 18.8 0.7 0.0016 18.3 0.7 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR64518.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family HTH_5 PF01022.20 KIR64519.1 - 1.2e-17 63.4 0.1 2e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR64519.1 - 5.3e-15 55.2 0.8 1e-14 54.3 0.8 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR64519.1 - 3.4e-06 26.8 0.2 6.1e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR64519.1 - 0.00028 20.4 0.0 0.00072 19.1 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR64519.1 - 0.00066 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KIR64519.1 - 0.0012 18.6 4.3 0.0056 16.5 2.7 2.5 2 1 0 2 2 2 1 IclR helix-turn-helix domain AbiEi_4 PF13338.6 KIR64519.1 - 0.0042 17.2 0.3 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin PaaX PF07848.12 KIR64519.1 - 0.0046 17.1 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 PaaX-like protein TrmB PF01978.19 KIR64519.1 - 0.0054 16.6 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 KIR64519.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_Crp_2 PF13545.6 KIR64519.1 - 0.013 15.4 0.5 0.052 13.5 0.5 2.0 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_34 PF13601.6 KIR64519.1 - 0.037 14.2 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_1 PF00126.27 KIR64519.1 - 0.053 13.5 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 KIR64519.1 - 0.062 13.5 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MCD_N PF17408.2 KIR64519.1 - 0.069 13.3 0.0 0.13 12.5 0.0 1.5 2 0 0 2 2 1 0 Malonyl-CoA decarboxylase N-terminal domain RepL PF05732.11 KIR64519.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Penicillinase_R PF03965.16 KIR64519.1 - 0.19 12.1 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor DUF11 PF01345.18 KIR64520.1 - 0.057 13.7 2.4 0.34 11.2 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF11 Bac_rhamnosid_C PF17390.2 KIR64520.1 - 0.073 12.9 0.0 9.8 6.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase C-terminal domain CBM_6 PF03422.15 KIR64520.1 - 0.098 13.0 1.8 9.6 6.5 0.3 3.3 2 1 2 4 4 4 0 Carbohydrate binding module (family 6) DUF4748 PF15932.5 KIR64520.1 - 0.1 12.4 0.4 0.21 11.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Phage_holin_4_2 PF04020.13 KIR64522.1 - 4.7e-31 107.6 17.6 5.3e-31 107.4 17.6 1.0 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV DUF1129 PF06570.11 KIR64522.1 - 1 8.8 6.2 5.5 6.4 6.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4605 PF15378.6 KIR64522.1 - 1.1 9.1 8.8 4.4 7.2 8.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4605) F_bP_aldolase PF01116.20 KIR64523.1 - 9.3e-82 274.6 0.2 1.1e-81 274.5 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF3151 PF11349.8 KIR64524.1 - 3.2e-54 182.4 1.8 3.6e-54 182.2 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3151) AAA_31 PF13614.6 KIR64525.1 - 0.00015 21.8 0.0 0.00029 20.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF4400 PF14348.6 KIR64525.1 - 0.0041 16.7 0.5 0.007 15.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) CbiA PF01656.23 KIR64525.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DAGK_cat PF00781.24 KIR64526.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain BAT PF15915.5 KIR64526.1 - 0.006 16.5 0.8 0.006 16.5 0.8 2.5 2 1 0 2 2 2 1 GAF and HTH_10 associated domain Imm1 PF14430.6 KIR64526.1 - 0.03 15.0 0.7 0.12 13.0 0.1 2.3 2 1 0 2 2 2 0 Immunity protein Imm1 DUF826 PF05696.11 KIR64526.1 - 0.32 11.1 1.6 0.73 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Adenylsucc_synt PF00709.21 KIR64527.1 - 1.6e-177 590.7 0.0 1.8e-177 590.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase GARS_A PF01071.19 KIR64528.1 - 1.9e-61 207.2 0.0 2.8e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KIR64528.1 - 3.6e-30 104.6 1.0 9e-30 103.3 1.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KIR64528.1 - 1.2e-22 80.0 2.8 1.2e-22 80.0 2.8 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 KIR64528.1 - 8e-06 26.0 0.0 2.6e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KIR64528.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 KIR64528.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Beta-lactamase PF00144.24 KIR64529.1 - 2.3e-53 181.6 6.8 3.1e-53 181.2 6.8 1.1 1 0 0 1 1 1 1 Beta-lactamase AMP-binding PF00501.28 KIR64530.1 - 5.6e-69 232.8 0.0 7e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR64530.1 - 4.4e-19 69.2 0.1 9.8e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.24 KIR64531.1 - 4.2e-50 169.9 1.1 7.1e-50 169.1 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KIR64531.1 - 8.5e-25 87.6 0.2 1.9e-24 86.5 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR64531.1 - 2.2e-22 79.1 0.0 3.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIR64531.1 - 9.9e-16 58.4 0.1 2.3e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SCP2 PF02036.17 KIR64532.1 - 6.1e-14 52.3 0.0 8.3e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIR64532.1 - 0.00017 21.9 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF1648 PF07853.11 KIR64532.1 - 0.074 12.7 0.1 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) TetR_N PF00440.23 KIR64533.1 - 3.3e-17 62.0 0.1 6.3e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KIR64533.1 - 2.7e-06 27.6 0.5 4.5e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 KIR64533.1 - 2.3e-05 25.1 4.5 3.4e-05 24.5 0.7 2.6 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 KIR64533.1 - 0.011 16.4 4.2 0.011 16.4 4.2 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 KIR64533.1 - 0.026 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TrmB PF01978.19 KIR64533.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ACT_5 PF13710.6 KIR64533.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ACT domain HTH_22 PF13309.6 KIR64533.1 - 0.19 11.8 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 HTH domain SNARE_assoc PF09335.11 KIR64534.1 - 2.7e-16 60.1 2.4 2.7e-16 60.1 2.4 1.6 1 1 0 1 1 1 1 SNARE associated Golgi protein FTR1 PF03239.14 KIR64534.1 - 0.056 12.6 0.3 0.056 12.6 0.3 2.0 2 0 0 2 2 2 0 Iron permease FTR1 family Adenylsucc_synt PF00709.21 KIR64535.1 - 6.4e-72 242.8 0.0 2.3e-71 241.0 0.0 1.7 2 0 0 2 2 2 1 Adenylosuccinate synthetase DUF444 PF04285.12 KIR64536.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Pkinase PF00069.25 KIR64537.1 - 0.0073 15.7 0.0 0.0088 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIR64537.1 - 0.084 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KIR64537.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDIX PF00293.28 KIR64538.1 - 5.4e-19 68.5 0.0 9.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.6 KIR64539.1 - 6.7e-52 176.4 6.9 5.8e-49 166.8 1.8 3.0 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR64539.1 - 8.3e-45 152.6 0.8 2e-44 151.4 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIR64539.1 - 1.7e-17 63.9 0.5 3e-17 63.1 0.5 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR64539.1 - 1e-05 25.2 0.2 1.5e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR64539.1 - 0.022 13.8 0.2 0.035 13.2 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ChW PF07538.11 KIR64539.1 - 0.13 12.2 0.1 0.38 10.7 0.1 1.8 1 0 0 1 1 1 0 Clostridial hydrophobic W Peptidase_M17_N PF02789.17 KIR64539.1 - 0.54 10.1 2.6 0.68 9.8 1.0 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain LytR_C PF13399.6 KIR64539.1 - 1.6 9.8 4.4 1.4e+02 3.5 0.6 3.7 3 1 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator Thiolase_N PF00108.23 KIR64540.1 - 1.9e-46 158.5 0.0 4.3e-46 157.4 0.0 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR64540.1 - 1.8e-31 108.4 0.0 3.2e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR64540.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glycos_transf_2 PF00535.26 KIR64541.1 - 1.9e-34 118.9 0.0 2.5e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR64541.1 - 4.6e-12 46.3 0.5 6.9e-12 45.7 0.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KIR64541.1 - 0.0015 19.0 0.0 0.0096 16.4 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIR64541.1 - 0.0078 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Lyase_1 PF00206.20 KIR64544.1 - 8.4e-23 81.2 0.1 1.9e-22 80.1 0.0 1.6 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 KIR64544.1 - 8.8e-13 48.6 0.7 8.8e-13 48.6 0.7 2.6 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ETF_alpha PF00766.19 KIR64544.1 - 0.16 12.0 0.4 0.92 9.6 0.1 2.4 2 1 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain Trypsin PF00089.26 KIR64545.1 - 6.6e-26 91.5 8.0 8.9e-26 91.1 8.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 KIR64545.1 - 1.5e-06 28.5 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) PigN PF04987.14 KIR64545.1 - 0.0063 15.4 1.7 0.0074 15.2 1.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) PurS PF02700.14 KIR64546.1 - 4.6e-25 87.6 0.0 5.3e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase DUF1161 PF06649.12 KIR64546.1 - 0.049 13.8 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) GATase_5 PF13507.6 KIR64547.1 - 2e-33 115.6 0.0 3.2e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 KIR64547.1 - 1.4e-07 31.4 0.0 3e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KIR64547.1 - 3.3e-06 27.0 0.0 4.5e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KIR64547.1 - 2.8e-05 24.0 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KIR64547.1 - 0.0051 16.6 0.4 0.024 14.4 0.4 2.0 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 KIR64547.1 - 0.0052 16.7 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family AIRS_C PF02769.22 KIR64548.1 - 1.6e-52 177.7 3.2 1.8e-33 115.9 0.6 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KIR64548.1 - 3.7e-47 158.9 4.2 5.4e-23 81.5 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 KIR64548.1 - 3.2e-16 59.6 0.0 6.5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain 2-ph_phosp PF04029.14 KIR64549.1 - 1.2e-18 67.2 0.0 1.5e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase CarboxypepD_reg PF13620.6 KIR64550.1 - 6.8e-08 32.7 6.0 7.8e-08 32.5 1.6 2.9 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KIR64550.1 - 0.00038 20.4 0.5 0.00081 19.3 0.1 1.8 2 0 0 2 2 2 1 CarboxypepD_reg-like domain BatD PF13584.6 KIR64550.1 - 0.03 13.1 0.6 0.23 10.2 0.0 2.3 1 1 2 3 3 3 0 Oxygen tolerance Cadherin_4 PF17803.1 KIR64550.1 - 9.1 7.0 15.2 35 5.1 0.4 3.6 2 1 0 2 2 2 0 Bacterial cadherin-like domain SCP_3 PF17844.1 KIR64551.1 - 8.1e-43 144.1 1.3 1.1e-42 143.8 1.3 1.1 1 0 0 1 1 1 1 Bacterial SCP ortholog MDMPI_C PF07398.11 KIR64551.1 - 8.7e-05 23.3 7.8 0.00018 22.3 7.8 1.6 1 1 0 1 1 1 1 MDMPI C-terminal domain SCP2_2 PF13530.6 KIR64551.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 1 1 2 2 2 0 Sterol carrier protein domain GATase_6 PF13522.6 KIR64552.1 - 1.9e-18 66.9 0.1 3.5e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIR64552.1 - 4.1e-18 65.5 0.0 6.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.21 KIR64552.1 - 7e-07 28.3 1.4 0.034 12.9 0.1 3.2 2 1 1 3 3 3 3 Glutamine amidotransferases class-II Pribosyltran PF00156.27 KIR64552.1 - 8.4e-07 28.6 0.2 2.4e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KIR64552.1 - 1.4e-06 27.4 0.1 8.2e-06 24.9 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II DUF3700 PF12481.8 KIR64552.1 - 0.0022 17.5 0.0 0.0061 16.0 0.0 1.7 1 1 0 1 1 1 1 Aluminium induced protein AIRS_C PF02769.22 KIR64553.1 - 7.2e-31 107.4 0.3 1.2e-30 106.8 0.3 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KIR64553.1 - 6.2e-17 62.0 0.2 9.7e-17 61.4 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Radical_SAM PF04055.21 KIR64554.1 - 4.1e-15 56.6 0.0 6.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KIR64554.1 - 0.0016 18.8 0.0 0.0037 17.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIR64554.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF3073 PF11273.8 KIR64556.1 - 4.8e-24 84.9 2.1 5.5e-24 84.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3073) Importin_rep_6 PF18829.1 KIR64556.1 - 0.074 13.2 5.0 0.082 13.0 5.0 1.2 1 0 0 1 1 1 0 Importin repeat 6 NOA36 PF06524.12 KIR64556.1 - 0.34 10.2 3.7 0.38 10.0 3.7 1.0 1 0 0 1 1 1 0 NOA36 protein ELFV_dehydrog_N PF02812.18 KIR64557.1 - 6.2e-26 90.8 0.0 2.3e-25 88.9 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 KIR64557.1 - 3.1e-15 56.6 1.1 1.9e-10 40.9 1.1 2.2 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KIR64557.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 KIR64557.1 - 0.00083 18.9 0.0 0.15 11.5 0.0 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KIR64557.1 - 0.00085 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KIR64557.1 - 0.0016 18.6 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 KIR64557.1 - 0.0097 16.3 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.6 KIR64557.1 - 0.011 15.7 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding AdoHcyase_NAD PF00670.21 KIR64557.1 - 0.037 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Actino_peptide PF14408.6 KIR64557.1 - 0.065 13.4 0.4 2.5 8.3 0.1 2.7 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes Putative_PNPOx PF01243.20 KIR64559.1 - 2.6e-05 24.3 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2255 PF10012.9 KIR64559.1 - 0.003 17.7 0.0 0.0073 16.4 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) Pyridox_ox_2 PF12900.7 KIR64559.1 - 0.0099 15.9 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F420H2_quin_red PF04075.14 KIR64559.1 - 0.074 13.2 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase Methyltransf_25 PF13649.6 KIR64560.1 - 1.9e-06 28.5 0.0 3.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64560.1 - 7.2e-06 26.6 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIR64560.1 - 0.001 18.7 0.2 0.0018 17.9 0.2 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 KIR64560.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR64560.1 - 0.023 15.4 0.0 0.044 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIR64560.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIR64560.1 - 0.062 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 KIR64560.1 - 0.18 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB EF-hand_5 PF13202.6 KIR64561.1 - 0.00079 18.8 21.8 0.009 15.5 0.7 4.8 5 0 0 5 5 5 3 EF hand EF-hand_1 PF00036.32 KIR64561.1 - 0.044 13.3 18.9 0.19 11.3 1.5 4.8 3 1 2 5 5 5 0 EF hand HA1 PF18239.1 KIR64561.1 - 0.06 13.2 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Hemagglutinin I VCBS PF13517.6 KIR64561.1 - 0.091 13.4 24.2 0.65 10.6 0.9 4.5 1 1 3 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella N_formyltrans_C PF18216.1 KIR64561.1 - 0.094 12.4 0.5 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 N-formyltransferase dimerization C-terminal domain TSP_3 PF02412.18 KIR64561.1 - 0.1 12.3 16.3 0.34 10.6 2.3 2.7 2 1 0 2 2 2 0 Thrombospondin type 3 repeat EF-hand_8 PF13833.6 KIR64561.1 - 1.2 9.0 14.8 0.56 10.1 0.7 3.9 2 1 2 4 4 4 0 EF-hand domain pair TcdB_toxin_midN PF12256.8 KIR64561.1 - 2.2 7.6 5.0 5.3 6.4 1.9 2.3 1 1 1 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region EF-hand_6 PF13405.6 KIR64561.1 - 3.5 7.8 15.3 0.36 10.9 0.9 4.4 3 1 2 5 5 5 0 EF-hand domain EF-hand_7 PF13499.6 KIR64561.1 - 4.5 7.8 9.6 12 6.4 1.0 3.8 2 1 2 4 4 4 0 EF-hand domain pair FG-GAP PF01839.23 KIR64561.1 - 7.4 6.8 29.2 0.72 10.0 1.7 4.8 4 1 1 5 5 5 0 FG-GAP repeat 3HCDH_N PF02737.18 KIR64562.1 - 3.6e-52 176.9 0.0 4.8e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIR64562.1 - 5.5e-31 107.1 0.0 1.3e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.24 KIR64562.1 - 0.00021 21.0 0.8 0.00028 20.6 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR64562.1 - 0.0021 17.3 0.9 0.0032 16.8 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR64562.1 - 0.012 16.2 0.6 0.023 15.2 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR64562.1 - 0.022 15.0 2.0 0.056 13.7 2.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIR64562.1 - 0.037 13.3 0.7 0.057 12.7 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KIR64562.1 - 0.063 13.3 0.3 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KIR64562.1 - 0.16 12.5 1.3 0.61 10.6 0.4 2.1 2 1 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.23 KIR64562.1 - 0.21 11.5 0.2 0.47 10.4 0.2 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 KIR64562.1 - 0.73 8.8 2.3 0.95 8.5 2.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A ECH_1 PF00378.20 KIR64563.1 - 3.9e-47 160.7 0.0 4.8e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR64563.1 - 6.2e-26 91.7 0.1 7.7e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peripla_BP_6 PF13458.6 KIR64564.1 - 2.7e-40 139.1 7.8 4.1e-38 131.9 1.9 2.1 2 0 0 2 2 2 2 Periplasmic binding protein ANF_receptor PF01094.28 KIR64564.1 - 6.5e-17 61.7 0.0 2.7e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_5 PF13433.6 KIR64564.1 - 1.2e-10 41.0 0.0 1.2e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein domain DUF2786 PF10979.8 KIR64566.1 - 2e-16 59.6 0.3 4.4e-16 58.5 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) AHSA1 PF08327.11 KIR64567.1 - 7.5e-11 42.3 0.3 9.6e-11 42.0 0.3 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein SecB PF02556.14 KIR64568.1 - 0.2 11.5 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit SecB Polysacc_deac_1 PF01522.21 KIR64569.1 - 1.8e-31 108.6 0.0 2.8e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase stn_TNFRSF12A PF12191.8 KIR64569.1 - 0.027 14.7 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3558 PF12079.8 KIR64569.1 - 0.33 10.9 4.8 0.67 9.9 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) MerR_1 PF13411.6 KIR64570.1 - 2.3e-14 53.2 0.0 3.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR64570.1 - 2.4e-07 30.4 0.3 6.2e-07 29.1 0.3 1.8 1 0 0 1 1 1 1 MerR family regulatory protein B12-binding PF02310.19 KIR64570.1 - 3.4e-07 30.3 0.1 7.4e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KIR64570.1 - 2.3e-05 24.8 0.5 2.3e-05 24.8 0.5 1.9 2 0 0 2 2 2 1 B12 binding domain HTH_23 PF13384.6 KIR64570.1 - 0.00038 20.1 0.4 0.013 15.3 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KIR64570.1 - 0.0097 15.9 0.2 0.79 9.8 0.0 3.3 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 KIR64570.1 - 0.016 15.4 6.7 0.19 11.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_17 PF12728.7 KIR64570.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KIR64570.1 - 0.023 15.0 0.3 0.11 12.8 0.1 2.2 1 1 1 2 2 2 0 Transposase CENP-B_N PF04218.13 KIR64570.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Arm-DNA-bind_3 PF13356.6 KIR64570.1 - 0.17 12.3 1.1 1 9.8 0.2 2.4 2 0 0 2 2 2 0 Arm DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KIR64570.1 - 0.25 10.8 4.6 0.22 10.9 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 NUDIX PF00293.28 KIR64571.1 - 1.2e-21 77.1 0.2 1.7e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIR64571.1 - 0.11 12.5 0.1 0.5 10.4 0.1 1.9 1 1 0 1 1 1 0 NUDIX domain Amino_oxidase PF01593.24 KIR64572.1 - 5.3e-33 115.0 0.2 8.4e-33 114.3 0.2 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KIR64572.1 - 7.9e-17 61.9 1.9 2.8e-16 60.1 1.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR64572.1 - 8.4e-12 45.2 0.7 2e-11 43.9 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR64572.1 - 6e-10 38.8 2.1 6.2e-05 22.4 1.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR64572.1 - 1e-07 32.4 3.1 0.0022 18.5 1.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR64572.1 - 3.2e-07 29.8 7.1 1.3e-05 24.5 4.8 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KIR64572.1 - 6.7e-06 25.1 0.2 0.0023 16.7 0.9 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KIR64572.1 - 1.3e-05 24.7 4.8 0.0004 19.8 4.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIR64572.1 - 0.00022 20.6 0.7 0.00044 19.6 0.7 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIR64572.1 - 0.0043 16.4 1.8 0.021 14.1 0.8 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR64572.1 - 0.0048 16.0 3.8 0.073 12.1 2.2 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIR64572.1 - 0.0052 16.1 4.6 0.028 13.7 3.1 2.1 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 KIR64572.1 - 0.028 13.2 0.0 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 MCRA family Trp_halogenase PF04820.14 KIR64572.1 - 0.1 11.4 6.3 1.3 7.8 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KIR64572.1 - 0.45 10.5 5.6 5.8 6.9 1.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIR64572.1 - 1.7 7.6 4.8 1.2 8.1 1.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein polyprenyl_synt PF00348.17 KIR64573.1 - 2.4e-54 184.1 0.0 3e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 KIR64574.1 - 4.7e-71 239.4 10.8 5.7e-71 239.1 10.8 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase FAD_binding_7 PF03441.14 KIR64575.1 - 2.1e-58 197.2 2.0 2.8e-58 196.7 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KIR64575.1 - 2.8e-43 147.8 0.0 4.1e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase Beta-lactamase PF00144.24 KIR64576.1 - 5.3e-60 203.4 5.5 6.3e-60 203.2 5.5 1.0 1 0 0 1 1 1 1 Beta-lactamase Pyr_redox_2 PF07992.14 KIR64577.1 - 7.4e-43 146.9 2.5 1.3e-42 146.0 2.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIR64577.1 - 4.4e-26 91.3 0.0 1.1e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIR64577.1 - 4.3e-15 56.1 9.9 1.6e-14 54.2 0.4 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIR64577.1 - 5e-06 26.0 0.3 0.0048 16.3 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIR64577.1 - 1.3e-05 25.2 2.8 0.0019 18.1 0.3 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIR64577.1 - 0.016 14.3 5.7 0.073 12.1 0.6 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A XdhC_C PF13478.6 KIR64577.1 - 0.024 15.2 1.1 0.085 13.4 0.2 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 KIR64577.1 - 0.039 13.2 0.6 1.2 8.4 0.4 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KIR64577.1 - 0.1 12.8 5.0 5.5 7.3 0.2 2.7 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 KIR64577.1 - 0.13 11.6 4.4 0.74 9.1 0.2 2.6 3 0 0 3 3 3 0 ThiF family UDPG_MGDP_dh_N PF03721.14 KIR64577.1 - 0.21 11.2 1.8 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KIR64577.1 - 0.44 9.8 8.1 0.087 12.1 0.8 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIR64577.1 - 0.58 10.6 2.5 0.6 10.6 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 KIR64577.1 - 0.85 9.3 4.8 14 5.3 0.1 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KIR64577.1 - 0.99 8.4 11.6 0.32 10.0 0.5 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein HI0933_like PF03486.14 KIR64577.1 - 1.5 7.4 8.1 1.6 7.3 0.4 2.4 2 1 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 KIR64577.1 - 1.9 7.6 11.6 0.055 12.7 0.5 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KIR64577.1 - 6.5 7.1 10.2 0.33 11.2 1.0 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ECH_1 PF00378.20 KIR64578.1 - 3.5e-38 131.3 0.0 4.4e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR64578.1 - 6.4e-17 62.0 0.0 3.6e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIR64578.1 - 0.033 14.1 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 Nitroreductase PF00881.24 KIR64579.1 - 3.5e-29 102.0 0.4 6.1e-29 101.3 0.4 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIR64579.1 - 0.00071 19.2 0.0 0.061 12.9 0.0 2.6 2 1 0 2 2 2 2 Putative TM nitroreductase Rieske PF00355.26 KIR64581.1 - 8.5e-13 48.1 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KIR64581.1 - 1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF2231 PF09990.9 KIR64581.1 - 0.00074 19.9 3.3 0.0012 19.2 3.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) LysM PF01476.20 KIR64582.1 - 2.8e-06 27.3 0.0 5.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF2970 PF11174.8 KIR64583.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) T2SSE PF00437.20 KIR64584.1 - 7.5e-32 110.5 0.3 1.1e-31 109.9 0.3 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KIR64584.1 - 4.8e-07 30.3 0.7 7.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KIR64584.1 - 0.00062 19.6 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 KIR64584.1 - 0.00081 18.7 0.1 0.0086 15.4 0.0 2.2 2 1 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KIR64584.1 - 0.00093 19.4 0.0 0.0049 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIR64584.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.6 KIR64584.1 - 0.0073 16.9 0.0 0.021 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KIR64584.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KIR64584.1 - 0.043 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIR64584.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIR64584.1 - 0.048 13.9 0.4 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain STAS_2 PF13466.6 KIR64584.1 - 0.12 12.8 11.9 0.29 11.5 4.2 3.3 4 0 0 4 4 2 0 STAS domain Septin PF00735.18 KIR64584.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin TrwB_AAD_bind PF10412.9 KIR64584.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain LptE PF04390.12 KIR64584.1 - 0.13 12.9 0.1 0.33 11.7 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide-assembly cobW PF02492.19 KIR64584.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SAF PF08666.12 KIR64586.1 - 2.6e-05 24.8 0.6 6.9e-05 23.4 0.3 1.9 2 0 0 2 2 2 1 SAF domain ChapFlgA PF13144.6 KIR64586.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation RcpC PF16976.5 KIR64586.1 - 0.14 12.2 4.1 0.29 11.2 0.6 2.7 2 1 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB Prot_ATP_ID_OB PF16450.5 KIR64586.1 - 2.4 8.2 5.7 1.1 9.3 0.1 2.9 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain FAP PF07174.11 KIR64587.1 - 0.095 12.1 4.9 0.12 11.9 4.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Peptidase_A24 PF01478.18 KIR64588.1 - 1.8e-10 41.1 14.0 1.8e-10 41.1 14.0 1.7 2 1 0 2 2 2 1 Type IV leader peptidase family DiS_P_DiS PF06750.13 KIR64588.1 - 0.0066 16.5 0.1 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial Peptidase A24 N-terminal domain Mu-like_Com PF10122.9 KIR64588.1 - 2.5 7.6 5.4 3.1 7.3 0.4 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com PAP2 PF01569.21 KIR64589.1 - 4.1e-20 71.9 1.0 7.7e-20 71.0 1.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KIR64589.1 - 1.2e-07 31.6 12.2 3.3e-07 30.2 12.3 1.7 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIR64589.1 - 0.075 13.2 1.6 2.6 8.2 0.2 2.3 1 1 1 2 2 2 0 Divergent PAP2 family PAP2_C PF14360.6 KIR64589.1 - 0.14 12.7 0.9 0.19 12.3 0.1 1.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Zn_ribbon_recom PF13408.6 KIR64590.1 - 0.13 12.8 0.1 1.1 9.8 0.1 2.1 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KIR64590.1 - 0.38 10.9 2.7 1.9 8.6 0.1 2.6 2 1 0 2 2 2 0 Zinc ribbon domain UPF0146 PF03686.13 KIR64592.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Pkinase PF00069.25 KIR64593.1 - 4.2e-45 154.2 0.0 5.8e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR64593.1 - 4.6e-27 94.9 0.0 5.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR64593.1 - 2.6e-09 37.4 1.6 0.0017 18.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIR64593.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIR64593.1 - 0.01 15.4 0.0 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.16 KIR64593.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase_fungal PF17667.1 KIR64593.1 - 0.018 13.8 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HTH_31 PF13560.6 KIR64594.1 - 2.5e-08 34.2 5.7 2.5e-08 34.2 5.7 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64594.1 - 2.5e-06 27.4 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 KIR64594.1 - 4.7e-06 27.0 0.0 7.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 KIR64594.1 - 0.0096 15.9 0.0 0.031 14.2 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KIR64594.1 - 0.011 15.5 1.5 4.5 7.1 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_19 PF12844.7 KIR64594.1 - 0.027 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SH3_4 PF06347.13 KIR64594.1 - 0.049 13.5 2.1 0.11 12.3 2.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DALR_1 PF05746.15 KIR64596.1 - 1.4e-19 70.4 0.0 1.6e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 DALR anticodon binding domain Replic_Relax PF13814.6 KIR64599.1 - 6.7e-49 166.6 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation DUF2637 PF10935.8 KIR64600.1 - 1.3e-10 41.4 9.0 1.3e-10 41.4 9.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2637) DUF4231 PF14015.6 KIR64600.1 - 5.9 7.4 8.0 14 6.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Mur_ligase_M PF08245.12 KIR64601.1 - 2.5e-42 145.0 0.0 3.7e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KIR64601.1 - 1e-18 67.3 0.7 1e-17 64.1 0.1 2.7 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 KIR64601.1 - 3.1e-11 43.4 0.3 1.7e-10 41.1 0.1 2.4 2 0 0 2 2 2 1 Mur ligase family, catalytic domain FIST PF08495.10 KIR64601.1 - 4.7 7.2 6.6 7.3 6.6 2.4 3.3 1 1 1 2 2 2 0 FIST N domain Mur_ligase PF01225.25 KIR64602.1 - 5.1e-21 74.8 0.6 1.4e-20 73.4 0.2 2.0 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 KIR64602.1 - 2.9e-18 66.6 0.0 4.1e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KIR64602.1 - 2.9e-13 49.9 0.7 1.7e-12 47.4 0.2 2.5 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain AAA_5 PF07728.14 KIR64604.1 - 0.0005 20.1 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KIR64604.1 - 0.003 17.5 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIR64604.1 - 0.0042 17.5 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR64604.1 - 0.0068 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Mg_chelatase PF01078.21 KIR64604.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIR64604.1 - 0.0084 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR64604.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIR64604.1 - 0.035 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KIR64604.1 - 0.059 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIR64604.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIR64604.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KIR64604.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIR64604.1 - 0.19 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KIR64604.1 - 0.24 11.1 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family kleA_kleC PF17383.2 KIR64605.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A ABC_tran PF00005.27 KIR64607.1 - 2.3e-29 102.7 0.0 2.9e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR64607.1 - 4.5e-13 49.7 0.1 3e-05 24.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR64607.1 - 4.5e-08 32.8 0.0 0.006 16.0 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR64607.1 - 2.3e-06 28.1 0.3 4.9e-06 27.0 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 KIR64607.1 - 1e-05 25.4 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KIR64607.1 - 2.4e-05 24.0 0.0 5.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR64607.1 - 0.0012 19.4 0.0 0.0018 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR64607.1 - 0.0013 19.0 0.1 0.0035 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR64607.1 - 0.0022 18.2 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR64607.1 - 0.0031 17.7 0.0 0.0059 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR64607.1 - 0.0038 17.2 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KIR64607.1 - 0.0043 16.8 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIR64607.1 - 0.0056 16.3 0.2 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIR64607.1 - 0.014 15.4 0.1 0.064 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KIR64607.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 KIR64607.1 - 0.018 14.6 0.0 0.046 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIR64607.1 - 0.024 15.0 0.0 0.049 14.0 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIR64607.1 - 0.035 14.0 0.0 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain ParA PF10609.9 KIR64607.1 - 0.061 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase cobW PF02492.19 KIR64607.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KIR64607.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 KIR64607.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 KIR64607.1 - 0.16 11.6 0.0 0.55 9.8 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 KIR64607.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2791 PF10923.8 KIR64607.1 - 0.22 10.3 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) FecCD PF01032.18 KIR64608.1 - 4.7e-62 209.8 32.1 5.8e-62 209.5 32.1 1.1 1 0 0 1 1 1 1 FecCD transport family FecCD PF01032.18 KIR64609.1 - 2.8e-82 276.2 30.4 3.6e-82 275.9 30.4 1.0 1 0 0 1 1 1 1 FecCD transport family 7TM-7TMR_HD PF07698.11 KIR64609.1 - 0.63 9.8 6.0 0.45 10.3 1.8 2.5 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Peripla_BP_2 PF01497.18 KIR64610.1 - 1.2e-24 87.3 0.0 1.5e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein FAD_binding_9 PF08021.11 KIR64611.1 - 3.7e-25 88.5 0.0 5.6e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 KIR64611.1 - 9.9e-22 77.7 0.0 1.7e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting protein Tricorn_C1 PF14684.6 KIR64611.1 - 0.099 12.7 0.2 0.27 11.4 0.2 1.6 2 0 0 2 2 2 0 Tricorn protease C1 domain GIT_SHD PF08518.11 KIR64612.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT Zip PF02535.22 KIR64613.1 - 4.4e-06 26.1 19.7 0.00036 19.9 9.1 2.3 1 1 0 2 2 2 2 ZIP Zinc transporter Nitrate_red_gam PF02665.14 KIR64613.1 - 0.71 9.4 5.6 0.53 9.8 0.4 2.4 2 0 0 2 2 2 0 Nitrate reductase gamma subunit Vut_1 PF02592.15 KIR64613.1 - 1.2 9.4 6.4 2.6 8.3 0.0 2.8 2 1 0 2 2 2 0 Putative vitamin uptake transporter DUF2178 PF09946.9 KIR64613.1 - 3.9 7.7 10.2 0.65 10.2 0.8 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) Acetyltransf_9 PF13527.7 KIR64614.1 - 5.5e-31 107.3 0.0 1.7e-30 105.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR64614.1 - 2.9e-09 37.2 0.0 2.3e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_17 PF17668.1 KIR64614.1 - 9.4e-08 32.9 0.7 2.1e-07 31.7 0.7 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR64614.1 - 8.6e-06 26.1 0.0 3.5e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR64614.1 - 0.00042 20.3 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 KIR64614.1 - 0.0016 18.8 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 Sterol carrier protein domain PP2C_2 PF13672.6 KIR64615.1 - 2.3e-14 53.5 2.4 3.5e-14 52.9 2.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KIR64615.1 - 2.3e-10 40.5 0.0 1.6e-08 34.5 0.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KIR64615.1 - 3.1e-06 27.3 4.2 5.3e-06 26.5 4.2 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) BenE PF03594.13 KIR64616.1 - 7.3e-101 337.7 53.5 9.1e-101 337.4 53.5 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein Amelogenin PF02948.15 KIR64616.1 - 0.017 15.8 1.8 0.028 15.1 1.8 1.2 1 0 0 1 1 1 0 Amelogenin DUF2171 PF09939.9 KIR64617.1 - 2e-05 24.8 0.2 0.041 14.2 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2171) MscL PF01741.18 KIR64619.1 - 1.6e-34 118.8 0.1 1.9e-34 118.6 0.1 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FCD PF07729.12 KIR64620.1 - 1.4e-22 80.5 14.5 2.8e-22 79.5 14.5 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KIR64620.1 - 3.5e-19 68.2 0.9 1.9e-18 65.9 0.6 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family DUF977 PF06163.11 KIR64620.1 - 0.002 18.1 0.2 0.0034 17.3 0.2 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) PaaX PF07848.12 KIR64620.1 - 0.069 13.4 0.1 0.3 11.3 0.0 2.1 2 1 1 3 3 3 0 PaaX-like protein RP-C PF03428.13 KIR64620.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.6 3 1 0 3 3 3 0 Replication protein C N-terminal domain STAS PF01740.21 KIR64621.1 - 8.8e-20 70.5 0.0 9.8e-20 70.3 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIR64621.1 - 1.9e-17 63.3 1.7 2.5e-17 63.0 1.7 1.2 1 0 0 1 1 1 1 STAS domain RsbRD_N PF14361.6 KIR64622.1 - 2.8e-24 85.8 1.8 2.8e-24 85.8 1.8 2.1 3 0 0 3 3 3 1 RsbT co-antagonist protein rsbRD N-terminal domain STAS PF01740.21 KIR64622.1 - 3.4e-10 39.6 0.1 1.1e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 STAS domain RHSP PF07999.11 KIR64622.1 - 0.056 12.2 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein STAS_2 PF13466.6 KIR64622.1 - 0.057 13.8 7.2 0.078 13.3 0.1 3.8 3 1 0 3 3 3 0 STAS domain STAS PF01740.21 KIR64623.1 - 1.6e-06 27.8 0.4 2e-06 27.4 0.4 1.1 1 0 0 1 1 1 1 STAS domain HATPase_c PF02518.26 KIR64624.1 - 1.3e-09 38.5 0.0 2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR64624.1 - 2.3e-07 30.8 0.1 2.9e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Glucodextran_B PF09136.10 KIR64624.1 - 0.049 14.0 0.1 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 Glucodextranase, domain B ECH_2 PF16113.5 KIR64624.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase SpoIIE PF07228.12 KIR64625.1 - 1.8e-40 138.9 2.9 4.2e-40 137.7 2.9 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 KIR64625.1 - 5.5e-23 81.3 0.0 1.3e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain DUF397 PF04149.12 KIR64627.1 - 1.3e-22 79.6 0.5 1.4e-22 79.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_18 PF12833.7 KIR64628.1 - 3.4e-18 65.7 0.2 7e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR64628.1 - 1.7e-07 31.1 0.0 1.7e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 KIR64628.1 - 0.3 11.3 2.3 35 4.6 0.2 3.2 2 1 0 2 2 2 0 Helix-turn-helix domain MDMPI_N PF11716.8 KIR64629.1 - 9.3e-12 45.8 12.8 1.7e-11 44.9 9.4 2.4 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.12 KIR64629.1 - 0.036 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 DinB family PhdYeFM_antitox PF02604.19 KIR64630.1 - 6.5e-25 86.7 0.9 7.7e-25 86.5 0.9 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 KIR64630.1 - 0.0016 18.5 0.1 0.0018 18.3 0.1 1.2 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system IPI_T4 PF11634.8 KIR64630.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 PhoU_div PF01865.16 KIR64630.1 - 0.062 12.6 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 E2_bind PF08825.10 KIR64630.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain DUF2330 PF10092.9 KIR64630.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) PadR PF03551.14 KIR64631.1 - 3.8e-15 55.6 0.0 5.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 KIR64631.1 - 0.0013 19.4 0.1 0.0026 18.4 0.1 1.5 1 0 0 1 1 1 1 Virulence activator alpha C-term Replic_Relax PF13814.6 KIR64631.1 - 0.0017 18.5 0.4 0.0041 17.2 0.0 1.6 1 1 1 2 2 2 1 Replication-relaxation BLACT_WH PF17778.1 KIR64631.1 - 0.012 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain HTH_34 PF13601.6 KIR64631.1 - 0.016 15.3 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HxlR PF01638.17 KIR64631.1 - 0.072 12.9 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 HxlR-like helix-turn-helix FtsX PF02687.21 KIR64632.1 - 3.4e-06 27.4 3.1 0.0017 18.7 0.0 5.2 5 2 0 5 5 5 2 FtsX-like permease family BPD_transp_2 PF02653.16 KIR64632.1 - 0.027 13.7 0.2 0.027 13.7 0.2 4.9 3 1 0 4 4 4 0 Branched-chain amino acid transport system / permease component PALP PF00291.25 KIR64633.1 - 4.3e-84 282.4 5.7 5.2e-84 282.1 5.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 KIR64633.1 - 0.02 14.7 0.3 0.036 13.9 0.3 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Lactamase_B_3 PF13483.6 KIR64633.1 - 0.18 11.7 0.1 0.44 10.4 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_S9_N PF02897.15 KIR64634.1 - 3.8e-103 345.5 0.0 4.7e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KIR64634.1 - 1.5e-62 210.8 0.0 2.2e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KIR64634.1 - 0.00066 18.4 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KIR64634.1 - 0.0025 17.4 0.6 0.016 14.8 0.2 2.1 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KIR64634.1 - 0.0042 17.0 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KIR64634.1 - 0.022 14.2 0.7 0.039 13.4 0.7 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase PD40 PF07676.12 KIR64634.1 - 0.066 13.2 2.0 0.12 12.3 0.3 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Esterase PF00756.20 KIR64634.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FAD_binding_4 PF01565.23 KIR64635.1 - 3.9e-21 75.2 0.9 9.2e-21 74.0 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain SpoIIE PF07228.12 KIR64636.1 - 1.1e-36 126.6 0.5 2.3e-36 125.5 0.5 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 KIR64636.1 - 2.5e-10 40.4 0.1 5.1e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_2 PF13185.6 KIR64636.1 - 1.1e-08 35.5 0.9 1.1e-06 28.9 0.2 2.9 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KIR64636.1 - 5.7e-07 29.9 0.0 1.2e-05 25.6 0.1 2.6 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 KIR64636.1 - 0.00025 21.7 0.4 0.0012 19.5 0.4 2.2 1 1 0 1 1 1 1 GAF domain HAMP PF00672.25 KIR64637.1 - 1.6e-71 236.5 33.7 2e-08 34.5 0.1 11.1 9 0 0 9 9 9 9 HAMP domain HATPase_c PF02518.26 KIR64637.1 - 2.7e-29 101.9 0.0 6.2e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIR64637.1 - 7.6e-25 87.3 0.3 2.3e-24 85.7 0.1 2.0 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.25 KIR64637.1 - 2.4e-17 62.7 0.6 2.4e-17 62.7 0.6 4.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KIR64637.1 - 1e-16 61.5 0.6 3.5e-16 59.8 0.2 2.3 2 0 0 2 2 1 1 GAF domain APG17 PF04108.12 KIR64637.1 - 1.3e-13 50.9 7.7 7.8e-06 25.2 0.0 5.7 2 1 2 4 4 4 3 Autophagy protein Apg17 Laminin_II PF06009.12 KIR64637.1 - 5.2e-12 46.0 43.7 0.11 12.5 0.5 8.6 8 0 0 8 8 8 5 Laminin Domain II DUF948 PF06103.11 KIR64637.1 - 1.2e-11 44.7 59.4 0.039 14.2 1.3 11.6 2 1 7 9 9 9 6 Bacterial protein of unknown function (DUF948) GAF PF01590.26 KIR64637.1 - 2.6e-08 34.6 0.1 8.9e-08 32.8 0.1 2.0 1 0 0 1 1 1 1 GAF domain SpoIIID PF12116.8 KIR64637.1 - 3.5e-08 33.4 0.3 26 5.0 0.0 7.7 7 0 0 7 7 7 0 Stage III sporulation protein D UPF0184 PF03670.13 KIR64637.1 - 6.2e-08 32.9 0.4 33 5.0 0.0 7.0 6 0 0 6 6 6 0 Uncharacterised protein family (UPF0184) WXG100 PF06013.12 KIR64637.1 - 1.4e-07 31.6 35.4 0.59 10.4 0.5 10.3 9 2 0 9 9 9 4 Proteins of 100 residues with WXG Syntaxin_2 PF14523.6 KIR64637.1 - 2.1e-07 31.2 25.3 1.2 9.6 0.0 8.6 3 1 5 8 8 8 2 Syntaxin-like protein DUF1759 PF03564.15 KIR64637.1 - 3.7e-07 30.2 11.6 6 6.8 0.0 7.0 8 0 0 8 8 7 1 Protein of unknown function (DUF1759) Focal_AT PF03623.13 KIR64637.1 - 5.6e-07 29.6 7.7 34 4.4 0.0 7.8 4 2 2 7 7 7 0 Focal adhesion targeting region PseudoU_synth_1 PF01416.20 KIR64637.1 - 8.4e-07 29.4 8.4 12 6.4 0.0 7.1 4 2 1 7 7 7 0 tRNA pseudouridine synthase DUF5082 PF16888.5 KIR64637.1 - 0.00044 20.5 20.2 8 6.8 0.0 7.3 4 1 3 7 7 7 0 Domain of unknown function (DUF5082) CclA_1 PF16942.5 KIR64637.1 - 0.0018 18.5 15.0 7.2 6.9 0.1 6.2 6 0 0 6 6 6 0 Putative cyclic bacteriocin DivIC PF04977.15 KIR64637.1 - 0.08 12.7 5.0 1.2 9.0 5.0 3.2 1 0 0 1 1 1 0 Septum formation initiator DUF1843 PF08898.10 KIR64637.1 - 0.19 12.2 26.1 7.8 7.1 0.2 8.1 9 0 0 9 9 7 0 Domain of unknown function (DUF1843) Jnk-SapK_ap_N PF09744.9 KIR64637.1 - 0.29 11.4 12.2 1.1 9.4 7.5 3.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Anillin_N PF16018.5 KIR64637.1 - 0.31 11.7 0.0 0.31 11.7 0.0 5.5 7 0 0 7 7 5 0 Anillin N-terminus OmpH PF03938.14 KIR64637.1 - 0.32 11.3 13.1 0.18 12.2 9.0 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Gp-FAR-1 PF05823.12 KIR64637.1 - 2 8.7 6.7 1.4e+02 2.8 0.0 5.8 2 1 5 7 7 7 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Atg14 PF10186.9 KIR64637.1 - 2.1 7.4 9.7 0.96 8.5 6.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3829 PF12889.7 KIR64637.1 - 3.7 6.9 13.7 36 3.7 0.0 6.1 4 1 5 9 9 9 0 Protein of unknown function (DUF3829) Response_reg PF00072.24 KIR64638.1 - 5.1e-25 87.8 0.0 7.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 KIR64638.1 - 0.0046 17.3 0.1 0.0093 16.3 0.0 1.5 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ MarR_2 PF12802.7 KIR64639.1 - 1.6e-09 37.5 0.1 2.8e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR64639.1 - 0.00023 21.6 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 KIR64639.1 - 0.00023 21.0 0.0 0.00071 19.4 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 KIR64639.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.5 2 0 0 2 2 2 1 HTH domain MarR PF01047.22 KIR64639.1 - 0.00087 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KIR64639.1 - 0.0027 17.5 0.1 0.0047 16.7 0.1 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain GntR PF00392.21 KIR64639.1 - 0.012 15.3 0.1 0.029 14.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 KIR64639.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_20 PF12840.7 KIR64639.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 KIR64639.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_AsnC-type PF13404.6 KIR64639.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF4423 PF14394.6 KIR64639.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) ABC_tran PF00005.27 KIR64640.1 - 1.6e-24 87.0 0.0 2.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR64640.1 - 7.4e-13 49.0 0.0 8.6e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KIR64640.1 - 4.1e-05 24.2 0.0 8.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KIR64640.1 - 0.028 14.8 0.2 0.051 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 KIR64640.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR64640.1 - 0.033 13.9 0.2 0.071 12.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR64640.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR64640.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR64640.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KIR64640.1 - 0.15 12.2 0.1 0.31 11.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain STAS_2 PF13466.6 KIR64641.1 - 2.7e-16 59.7 2.9 3.3e-16 59.4 2.9 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KIR64641.1 - 7.9e-11 41.6 0.0 9e-11 41.4 0.0 1.0 1 0 0 1 1 1 1 STAS domain Aminotran_3 PF00202.21 KIR64642.1 - 4.4e-82 275.9 0.0 5.1e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIR64642.1 - 0.0002 20.6 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II His_Phos_1 PF00300.22 KIR64643.1 - 6.6e-36 123.8 0.3 8.8e-36 123.4 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AhpC-TSA PF00578.21 KIR64644.1 - 2.8e-18 66.0 0.0 3.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR64644.1 - 2.8e-16 59.5 0.0 3.7e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 KIR64644.1 - 3.7e-09 36.8 0.0 5.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 KIR64644.1 - 9.3e-08 32.0 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIR64644.1 - 0.00015 22.2 0.0 0.00021 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIR64644.1 - 0.0073 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 KIR64645.1 - 2.2e-46 158.4 14.4 1.9e-35 122.7 9.5 2.1 2 0 0 2 2 2 2 Cytochrome C biogenesis protein transmembrane region ResB PF05140.14 KIR64646.1 - 3.1e-120 402.2 0.0 5.4e-120 401.4 0.0 1.4 1 1 0 1 1 1 1 ResB-like family Cytochrom_C_asm PF01578.20 KIR64647.1 - 2e-42 145.4 17.0 3.2e-42 144.7 17.0 1.3 1 0 0 1 1 1 1 Cytochrome C assembly protein Vma12 PF11712.8 KIR64647.1 - 0.044 13.9 1.7 0.11 12.5 1.7 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Metallophos PF00149.28 KIR64648.1 - 1.2e-06 29.1 0.0 2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_31 PF13560.6 KIR64650.1 - 1.7e-12 47.5 0.6 2e-11 44.1 0.0 2.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64650.1 - 3.8e-08 33.3 0.0 9.5e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR64650.1 - 0.00032 20.7 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KIR64650.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 KIR64650.1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_AsnC-type PF13404.6 KIR64650.1 - 0.021 14.7 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain CobA_CobO_BtuR PF02572.15 KIR64650.1 - 0.026 14.8 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP HTH_38 PF13936.6 KIR64650.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF397 PF04149.12 KIR64651.1 - 1.2e-22 79.7 1.1 1.4e-22 79.5 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) UbiD PF01977.16 KIR64652.1 - 4.7e-156 519.7 0.0 5.3e-156 519.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiA PF01040.18 KIR64653.1 - 1.2e-49 169.0 31.8 1.5e-49 168.6 31.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Phage_holin_2_4 PF16082.5 KIR64653.1 - 3.6 7.4 12.2 0.66 9.7 2.5 3.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Flavoprotein PF02441.19 KIR64654.1 - 2.1e-15 56.8 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein HTH_17 PF12728.7 KIR64655.1 - 8.6e-12 45.1 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 KIR64655.1 - 6.5e-07 29.0 0.0 9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 KIR64655.1 - 4.3e-05 23.5 0.0 5.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_29 PF13551.6 KIR64655.1 - 0.088 12.8 0.2 0.34 11.0 0.1 2.0 1 1 1 2 2 2 0 Winged helix-turn helix HTH_AsnC-type PF13404.6 KIR64656.1 - 3.6e-17 61.9 0.1 6.1e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR64656.1 - 9.8e-16 57.1 0.1 2.7e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KIR64656.1 - 1.9e-15 56.5 0.0 3.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 KIR64656.1 - 5.5e-05 23.0 0.4 0.00015 21.6 0.2 1.8 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 KIR64656.1 - 0.00033 20.4 0.4 0.00033 20.4 0.4 2.2 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_20 PF12840.7 KIR64656.1 - 0.0014 18.6 0.2 0.003 17.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 KIR64656.1 - 0.005 16.7 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 HTH domain DprA_WH PF17782.1 KIR64656.1 - 0.037 14.2 1.0 0.1 12.7 0.2 2.1 3 0 0 3 3 3 0 DprA winged helix domain LexA_DNA_bind PF01726.16 KIR64656.1 - 0.038 13.8 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain MarR PF01047.22 KIR64656.1 - 0.04 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Sigma70_r4_2 PF08281.12 KIR64656.1 - 0.067 12.9 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KIR64656.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF501 PF04417.12 KIR64656.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Fe_dep_repress PF01325.19 KIR64656.1 - 0.074 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 KIR64656.1 - 0.089 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 KIR64656.1 - 0.095 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB EF1_GNE PF00736.19 KIR64656.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain HTH_1 PF00126.27 KIR64656.1 - 0.12 12.4 0.4 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_10 PF04967.12 KIR64656.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain PCI PF01399.27 KIR64656.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 PCI domain PALP PF00291.25 KIR64657.1 - 8.9e-46 156.6 0.0 1.1e-45 156.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glycolipid_bind PF06475.11 KIR64658.1 - 8.3e-43 145.9 0.0 1.4e-41 141.9 0.0 2.1 1 1 0 1 1 1 1 Putative glycolipid-binding DEAD PF00270.29 KIR64659.1 - 1.3e-42 145.5 0.0 1.9e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR64659.1 - 1.3e-22 80.2 0.0 2.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR64659.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NLPC_P60 PF00877.19 KIR64660.1 - 1.1e-22 80.1 0.0 2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 KIR64660.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase TPR_MLP1_2 PF07926.12 KIR64660.1 - 0.5 10.4 15.6 1.4 9.0 7.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KIR64660.1 - 0.6 10.2 6.3 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIR64660.1 - 5.2 6.3 15.0 13 5.0 15.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KIR64660.1 - 6.5 7.3 12.2 5.4 7.5 6.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Radical_SAM PF04055.21 KIR64661.1 - 7.2e-12 46.0 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF4229 PF14012.6 KIR64663.1 - 4.1e-15 55.6 3.8 5.2e-15 55.3 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) YIF1 PF03878.15 KIR64663.1 - 0.11 11.9 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 YIF1 Peptidase_C39_2 PF13529.6 KIR64664.1 - 9.4e-30 104.1 0.0 1.6e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 KIR64664.1 - 2.2e-09 37.4 0.0 4.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 KIR64664.1 - 0.065 13.0 0.0 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C39 family Peptidase_M14 PF00246.24 KIR64665.1 - 1e-68 232.3 0.5 1.2e-68 232.0 0.5 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peripla_BP_2 PF01497.18 KIR64666.1 - 7.9e-40 136.9 0.2 9.5e-40 136.6 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 KIR64667.1 - 2.4e-87 292.9 28.8 2.9e-87 292.6 28.8 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 KIR64667.1 - 6e-09 35.8 10.9 1.1e-08 34.9 10.9 1.5 1 0 0 1 1 1 1 ABC 3 transport family Glyoxalase_6 PF18029.1 KIR64668.1 - 4.3e-19 69.3 7.7 1.4e-10 42.0 0.3 2.8 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase PF00903.25 KIR64668.1 - 3.1e-10 40.3 0.0 9.9e-06 25.8 0.0 2.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ABC2_membrane PF01061.24 KIR64669.1 - 4.2e-12 45.9 13.7 6.7e-12 45.3 13.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR64669.1 - 0.00094 18.4 13.6 0.00094 18.4 13.6 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein EMP70 PF02990.16 KIR64669.1 - 1.1 7.9 2.4 1.2 7.8 2.4 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 ABC_tran PF00005.27 KIR64670.1 - 3.8e-30 105.2 0.0 1.1e-28 100.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KIR64670.1 - 5.3e-15 56.0 0.2 4.2e-08 33.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIR64670.1 - 0.00077 19.7 0.0 0.012 15.9 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KIR64670.1 - 0.0025 17.3 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR64670.1 - 0.0036 17.4 0.1 0.0091 16.1 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KIR64670.1 - 0.0047 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR64670.1 - 0.0054 16.7 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KIR64670.1 - 0.009 16.5 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF4162 PF13732.6 KIR64670.1 - 0.015 16.0 0.0 0.028 15.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Dynamin_N PF00350.23 KIR64670.1 - 0.07 13.2 0.1 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AAA_27 PF13514.6 KIR64670.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIR64671.1 - 6.3e-09 36.3 0.0 8.2e-07 29.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 KIR64671.1 - 6.2e-07 29.2 0.0 0.028 14.0 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KIR64671.1 - 2.2e-05 23.9 0.0 0.012 14.9 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 KIR64671.1 - 3.7e-05 23.4 0.2 9.7e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIR64671.1 - 0.0001 22.1 0.1 0.034 13.9 0.0 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIR64671.1 - 0.00023 20.9 3.5 0.75 9.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain PhoH PF02562.16 KIR64671.1 - 0.001 18.6 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 KIR64671.1 - 0.029 14.4 0.0 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KIR64671.1 - 0.041 13.7 0.2 0.46 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIR64671.1 - 0.078 13.2 0.0 8.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIR64671.1 - 0.079 13.3 0.1 0.079 13.3 0.1 3.3 3 1 1 4 4 4 0 AAA ATPase domain MEDS PF14417.6 KIR64671.1 - 0.08 12.8 2.5 0.27 11.0 0.1 2.8 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DEAD PF00270.29 KIR64671.1 - 0.085 12.6 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase HTH_20 PF12840.7 KIR64672.1 - 3.6e-14 52.6 1.1 6.7e-14 51.7 0.4 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 KIR64672.1 - 4.1e-11 42.6 0.0 7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 KIR64672.1 - 1.8e-06 27.7 0.5 4.1e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR64672.1 - 4e-06 26.6 0.1 9.8e-06 25.4 0.1 1.8 1 1 0 1 1 1 1 MarR family FaeA PF04703.12 KIR64672.1 - 4.9e-05 23.6 0.0 8.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FaeA-like protein MarR PF01047.22 KIR64672.1 - 0.00012 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR64672.1 - 0.00032 20.2 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KIR64672.1 - 0.013 15.3 0.8 0.048 13.5 0.0 2.3 2 1 1 3 3 3 0 HTH DNA binding domain TrmB PF01978.19 KIR64672.1 - 0.015 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 KIR64672.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 KIR64672.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.8 1 1 0 1 1 1 0 LexA DNA binding domain HTH_34 PF13601.6 KIR64672.1 - 0.025 14.7 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 KIR64672.1 - 0.042 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Dimerisation2 PF16864.5 KIR64672.1 - 0.074 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain HTH_Crp_2 PF13545.6 KIR64672.1 - 0.082 12.9 0.0 0.39 10.7 0.0 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Peptidase_S8 PF00082.22 KIR64673.1 - 3e-34 118.6 20.6 4.4e-34 118.1 20.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIR64673.1 - 4.8e-08 33.6 0.0 1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 VitK2_biosynth PF02621.14 KIR64674.1 - 1.2e-74 251.2 0.0 1.4e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis Beta-lactamase2 PF13354.6 KIR64675.1 - 3.8e-05 23.4 0.0 0.049 13.2 0.0 2.2 1 1 1 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KIR64675.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PaaA_PaaC PF05138.12 KIR64677.1 - 1.1e-103 346.0 0.3 1.4e-103 345.7 0.3 1.0 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein PaaB PF06243.11 KIR64678.1 - 7.6e-39 131.8 0.0 9.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 Phenylacetic acid degradation B PaaA_PaaC PF05138.12 KIR64679.1 - 7.7e-87 290.8 0.2 9.4e-87 290.5 0.2 1.1 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein FeS_assembly_P PF01883.19 KIR64680.1 - 1.1e-11 44.7 1.0 1.9e-11 43.9 1.0 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Zn_Tnp_IS1595 PF12760.7 KIR64680.1 - 0.0021 18.0 2.6 0.0039 17.1 2.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 KIR64680.1 - 0.0063 16.2 2.4 0.012 15.3 1.4 1.9 2 0 0 2 2 2 1 InsA N-terminal domain Zn-ribbon_8 PF09723.10 KIR64680.1 - 0.02 15.0 0.8 6.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 KIR64680.1 - 1.3 8.8 6.5 1.5 8.6 1.6 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain NAD_binding_1 PF00175.21 KIR64681.1 - 6.2e-15 55.8 0.0 9.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 KIR64681.1 - 1.2e-13 50.7 0.2 2.1e-13 50.0 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 KIR64681.1 - 1.8e-12 47.5 0.0 2.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain adh_short PF00106.25 KIR64682.1 - 7.3e-28 97.3 0.1 1.1e-27 96.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR64682.1 - 5.3e-17 62.2 0.4 7.6e-17 61.6 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIR64682.1 - 0.0011 18.5 0.1 0.0014 18.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_31 PF13560.6 KIR64684.1 - 1.9e-14 53.7 0.9 1.9e-14 53.7 0.9 3.4 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64684.1 - 0.00048 20.1 0.1 0.00098 19.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR64684.1 - 0.0016 18.4 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR64684.1 - 0.0063 16.4 0.2 0.016 15.0 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR64684.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MdcG PF10620.9 KIR64684.1 - 0.088 12.6 5.5 0.024 14.4 2.2 1.8 2 1 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF397 PF04149.12 KIR64685.1 - 4.2e-24 84.4 1.1 4.7e-24 84.2 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Radical_SAM PF04055.21 KIR64686.1 - 2.7e-17 63.7 0.0 4.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF11 PF01345.18 KIR64687.1 - 0.011 16.0 7.5 0.13 12.5 0.2 3.6 2 1 0 3 3 3 0 Domain of unknown function DUF11 NPCBM_assoc PF10633.9 KIR64687.1 - 0.036 14.3 2.4 0.64 10.3 0.0 3.4 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Gram_pos_anchor PF00746.21 KIR64688.1 - 0.013 15.5 2.2 0.013 15.5 2.2 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PT PF04886.12 KIR64688.1 - 0.24 11.0 21.4 0.57 9.8 21.4 1.6 1 0 0 1 1 1 0 PT repeat Ubie_methyltran PF01209.18 KIR64689.1 - 6.5e-53 179.5 0.0 7.9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KIR64689.1 - 2.8e-22 79.2 0.0 4.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR64689.1 - 7.6e-19 68.2 0.0 1.4e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR64689.1 - 4.9e-12 46.0 0.0 1.2e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR64689.1 - 3.1e-11 43.3 0.0 4.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR64689.1 - 1.5e-10 41.7 0.0 2.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIR64689.1 - 0.00018 21.2 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KIR64689.1 - 0.004 17.0 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KIR64689.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_29 PF03141.16 KIR64689.1 - 0.066 11.7 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KIR64689.1 - 0.088 12.6 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KIR64689.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.17 KIR64689.1 - 0.23 10.6 0.1 0.55 9.4 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF2267 PF10025.9 KIR64690.1 - 0.0061 16.8 0.9 0.0082 16.4 0.8 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) FAD_binding_3 PF01494.19 KIR64691.1 - 5.3e-18 65.4 0.1 1.9e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIR64691.1 - 7.7e-13 48.7 0.9 3.2e-07 30.3 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR64691.1 - 9.7e-09 34.8 0.1 1.6e-05 24.2 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KIR64691.1 - 6.9e-08 31.9 0.8 0.0064 15.6 0.1 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIR64691.1 - 8.6e-08 32.3 0.1 2.1e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIR64691.1 - 3.7e-07 29.4 0.0 0.00017 20.6 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.17 KIR64691.1 - 6.6e-07 28.8 0.0 7e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KIR64691.1 - 1.2e-06 28.0 0.2 3.4e-06 26.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR64691.1 - 3.2e-06 26.8 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR64691.1 - 1.7e-05 23.7 0.0 8.1e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KIR64691.1 - 2e-05 23.9 0.0 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIR64691.1 - 0.0077 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR64691.1 - 0.019 15.5 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIR64691.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIR64691.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KIR64691.1 - 0.16 11.4 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Oxidored_q4 PF00507.19 KIR64692.1 - 5.8e-35 119.4 0.8 7.6e-35 119.0 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF5373 PF17343.2 KIR64692.1 - 0.016 15.1 1.0 0.024 14.5 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF4212 PF13937.6 KIR64692.1 - 0.14 12.5 0.4 0.14 12.5 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Oxidored_q6 PF01058.22 KIR64693.1 - 1.1e-22 80.2 0.1 1.6e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.19 KIR64694.1 - 6.4e-47 159.2 0.0 9e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_49kDa PF00346.19 KIR64695.1 - 1.5e-110 368.6 0.0 1.9e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DBC1 PF14443.6 KIR64695.1 - 0.062 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 DBC1 NiFeSe_Hases PF00374.19 KIR64695.1 - 0.15 11.0 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 Nickel-dependent hydrogenase 2Fe-2S_thioredx PF01257.19 KIR64696.1 - 4.3e-49 166.1 0.0 5.6e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.11 KIR64696.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) Complex1_51K PF01512.17 KIR64697.1 - 1.7e-47 161.1 0.0 2.9e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KIR64697.1 - 1.7e-29 101.7 0.0 2.9e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KIR64697.1 - 6.1e-09 35.6 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 SLBB domain TNFR_c6 PF00020.18 KIR64697.1 - 0.23 11.9 2.4 0.44 11.0 2.4 1.5 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region Molybdopterin PF00384.22 KIR64698.1 - 9.5e-23 80.8 0.0 3.4e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KIR64698.1 - 1.2e-19 70.2 1.1 5.3e-19 68.1 1.1 2.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KIR64698.1 - 1.9e-15 56.1 0.4 3.9e-15 55.1 0.4 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molydop_binding PF01568.21 KIR64698.1 - 2.2e-10 40.6 0.1 9.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Fer2 PF00111.27 KIR64698.1 - 8.2e-07 28.9 1.8 1.2e-06 28.4 0.3 2.1 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdop_Fe4S4 PF04879.16 KIR64698.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4 PF00037.27 KIR64698.1 - 0.16 11.8 3.8 3 7.8 0.2 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_7 PF12838.7 KIR64698.1 - 0.34 11.5 7.0 3.9 8.2 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain NADHdh PF00146.21 KIR64699.1 - 9.5e-124 412.5 21.1 1.1e-123 412.3 21.1 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.27 KIR64700.1 - 3.9e-16 58.1 11.3 3.8e-08 32.8 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIR64700.1 - 2.8e-11 43.8 6.8 4.6e-11 43.1 6.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR64700.1 - 5.5e-11 42.4 17.2 1.3e-08 34.8 8.6 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR64700.1 - 9.7e-10 39.2 2.9 0.00025 21.9 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KIR64700.1 - 2.6e-09 37.1 17.4 6.4e-08 32.6 8.1 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KIR64700.1 - 4.4e-09 36.3 4.9 0.00034 20.7 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR64700.1 - 1.2e-08 34.7 11.6 0.00011 22.1 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KIR64700.1 - 2.3e-08 33.6 11.2 0.00035 20.5 2.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KIR64700.1 - 3.4e-07 30.6 5.7 0.0019 18.6 0.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIR64700.1 - 1.4e-05 25.7 14.2 0.0055 17.6 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIR64700.1 - 1.7e-05 25.0 8.5 0.0069 16.8 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIR64700.1 - 2.4e-05 24.8 8.4 0.003 18.1 10.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIR64700.1 - 6.2e-05 23.5 9.0 0.018 15.6 1.2 2.8 3 0 0 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KIR64700.1 - 0.0023 18.1 5.5 0.23 11.7 0.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 KIR64700.1 - 0.12 13.2 9.6 4.3 8.2 1.3 2.2 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KIR64700.1 - 0.18 12.5 0.2 0.18 12.5 0.2 3.3 3 1 0 3 3 3 0 4Fe-4S single cluster domain SPATA9 PF15824.5 KIR64700.1 - 0.28 10.4 0.0 0.37 10.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 Oxidored_q3 PF00499.20 KIR64701.1 - 7.7e-34 116.5 16.6 9.8e-34 116.1 16.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 EI24 PF07264.11 KIR64701.1 - 0.092 13.0 7.3 0.41 10.9 6.5 2.0 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Otopetrin PF03189.13 KIR64701.1 - 0.49 9.2 2.5 0.78 8.5 1.9 1.6 2 0 0 2 2 2 0 Otopetrin Oxidored_q2 PF00420.24 KIR64702.1 - 8.8e-24 83.2 10.2 1.1e-23 82.9 10.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Gram_pos_anchor PF00746.21 KIR64702.1 - 0.16 12.0 1.3 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif ATP1G1_PLM_MAT8 PF02038.16 KIR64702.1 - 0.59 9.6 5.1 3.5 7.1 1.2 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Proton_antipo_M PF00361.20 KIR64703.1 - 2.6e-82 276.3 14.6 2.6e-82 276.3 14.6 2.3 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 KIR64703.1 - 4.4e-23 81.1 0.6 4.4e-23 81.1 0.6 2.4 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 KIR64703.1 - 0.00034 20.3 0.8 0.0097 15.5 0.0 3.1 3 0 0 3 3 3 1 NADH dehydrogenase subunit 5 C-terminus Proton_antipo_C PF01010.19 KIR64703.1 - 0.0027 17.4 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus PIRT PF15099.6 KIR64703.1 - 0.92 9.1 3.6 7.8 6.1 0.5 2.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Proton_antipo_M PF00361.20 KIR64704.1 - 2.9e-58 197.4 20.5 2.9e-58 197.4 20.5 2.1 2 0 0 2 2 2 1 Proton-conducting membrane transporter DUF4536 PF15055.6 KIR64704.1 - 0.033 14.4 0.4 4.8 7.5 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Oxidored_q5_N PF01059.17 KIR64704.1 - 5.3 7.2 12.5 0.049 13.7 2.7 2.8 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 KIR64705.1 - 1.2e-69 234.8 20.3 1.2e-69 234.8 20.3 1.6 2 0 0 2 2 2 1 Proton-conducting membrane transporter UPF0715 PF17094.5 KIR64705.1 - 5.8 7.5 13.8 0.1 13.1 2.8 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) polyprenyl_synt PF00348.17 KIR64706.1 - 2.4e-56 190.6 0.0 3.2e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase IclR PF01614.18 KIR64707.1 - 3.6e-16 59.2 0.2 7.9e-16 58.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR64707.1 - 1.7e-13 50.2 0.3 4.2e-13 48.9 0.3 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR64707.1 - 1.3e-06 28.2 0.3 3.9e-06 26.7 0.3 1.9 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR64707.1 - 0.0015 18.6 0.1 0.0093 16.0 0.1 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KIR64707.1 - 0.0032 17.4 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR64707.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KIR64707.1 - 0.015 15.2 0.1 0.042 13.7 0.0 1.8 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 KIR64707.1 - 0.029 14.2 0.2 0.09 12.6 0.2 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DUF839 PF05787.13 KIR64708.1 - 1.1e-166 556.1 0.1 1.3e-166 555.9 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) zf-HC2 PF13490.6 KIR64709.1 - 5.1e-07 29.8 1.2 5.1e-07 29.8 1.2 2.3 2 0 0 2 2 2 1 Putative zinc-finger RskA PF10099.9 KIR64709.1 - 0.95 9.7 11.7 1.5 9.1 11.8 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Acetyltransf_1 PF00583.25 KIR64710.1 - 1.5e-08 34.9 0.0 1.8e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR64710.1 - 5.3e-07 29.6 0.0 6.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR64710.1 - 1.7e-05 25.2 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR64710.1 - 1.7e-05 24.7 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 KIR64710.1 - 0.027 14.6 2.8 0.039 14.1 2.8 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR64710.1 - 0.12 12.6 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 KIR64710.1 - 0.18 11.5 0.2 0.28 10.9 0.2 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Phage_holin_4_2 PF04020.13 KIR64711.1 - 4.4e-26 91.6 15.9 5e-26 91.4 15.9 1.0 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV Peptidase_M48_N PF16491.5 KIR64711.1 - 0.4 10.6 5.7 0.83 9.5 5.7 1.5 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices DUF2583 PF10762.9 KIR64711.1 - 1.1 9.7 10.9 0.15 12.5 5.2 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2583) WXG100 PF06013.12 KIR64713.1 - 5.3e-15 55.4 4.9 5.8e-15 55.3 4.9 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF3584 PF12128.8 KIR64713.1 - 0.00045 17.9 1.3 0.00051 17.7 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PilJ PF13675.6 KIR64713.1 - 0.001 19.1 2.3 0.0013 18.8 2.3 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term MbeD_MobD PF04899.12 KIR64713.1 - 0.0019 18.2 2.4 0.0072 16.4 0.6 2.0 2 0 0 2 2 2 1 MbeD/MobD like OmpH PF03938.14 KIR64713.1 - 0.014 15.7 0.2 0.017 15.5 0.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Taxilin PF09728.9 KIR64713.1 - 0.048 12.8 0.0 0.052 12.7 0.0 1.0 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Syntaxin-6_N PF09177.11 KIR64713.1 - 0.051 14.1 0.9 1.4 9.5 0.7 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YlqD PF11068.8 KIR64713.1 - 0.053 13.9 0.2 0.061 13.7 0.2 1.1 1 0 0 1 1 1 0 YlqD protein DUF883 PF05957.13 KIR64713.1 - 0.063 13.9 2.2 0.087 13.4 2.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) T7SS_ESX_EspC PF10824.8 KIR64713.1 - 0.23 11.9 4.5 0.38 11.3 4.5 1.3 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm KfrA_N PF11740.8 KIR64713.1 - 0.63 10.7 9.4 2.9 8.6 9.4 1.8 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Peptidase_S8 PF00082.22 KIR64714.1 - 3.7e-43 147.9 1.4 1.4e-42 146.0 1.4 1.8 1 1 0 1 1 1 1 Subtilase family SH3_3 PF08239.11 KIR64715.1 - 0.11 12.8 0.2 0.39 11.0 0.1 2.1 2 1 0 2 2 2 0 Bacterial SH3 domain Abhydrolase_1 PF00561.20 KIR64716.1 - 1e-20 74.5 0.2 1.5e-20 74.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR64716.1 - 1.3e-17 65.2 20.9 1.8e-17 64.7 20.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR64716.1 - 2.9e-11 43.1 0.5 6e-11 42.1 0.5 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KIR64716.1 - 0.014 14.0 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KIR64716.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIR64716.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Peptidase_M6 PF05547.11 KIR64717.1 - 1.2e-170 569.1 20.7 1.8e-170 568.5 20.7 1.2 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 AMP-binding PF00501.28 KIR64718.1 - 8.6e-95 317.8 0.4 1e-94 317.5 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR64718.1 - 3.5e-27 95.2 3.7 7.7e-27 94.1 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KIR64718.1 - 2.4e-20 72.2 2.4 6.5e-20 70.8 2.4 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus MlrC_C PF07171.12 KIR64718.1 - 0.012 15.8 0.6 0.027 14.7 0.6 1.5 1 0 0 1 1 1 0 MlrC C-terminus VbhA PF18495.1 KIR64719.1 - 0.0081 16.0 0.3 0.0081 16.0 0.3 2.7 3 0 0 3 3 3 1 Antitoxin VbhA Aldolase PF01081.19 KIR64719.1 - 0.067 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase HAD PF12710.7 KIR64720.1 - 3.1e-32 112.5 0.5 4.1e-32 112.1 0.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR64720.1 - 0.00098 19.5 0.1 0.0015 18.9 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR64720.1 - 0.0011 18.8 0.0 0.0095 15.7 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NUDIX PF00293.28 KIR64721.1 - 4.9e-16 59.0 0.0 5.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIR64721.1 - 0.0042 17.1 0.0 0.0062 16.5 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain RibD_C PF01872.17 KIR64722.1 - 1.4e-10 41.3 0.0 1.9e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain DUF87 PF01935.17 KIR64724.1 - 5.1e-09 36.6 0.0 1.5e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KIR64724.1 - 8.6e-06 26.2 4.8 0.00032 21.1 1.5 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KIR64724.1 - 9.1e-06 26.0 0.1 0.61 10.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KIR64724.1 - 0.0001 22.1 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 KIR64724.1 - 0.0002 20.4 1.5 0.0037 16.2 0.0 2.5 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KIR64724.1 - 0.00074 18.8 0.1 0.07 12.4 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin Zot PF05707.12 KIR64724.1 - 0.0018 18.0 0.0 0.0064 16.2 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) NACHT PF05729.12 KIR64724.1 - 0.0032 17.4 0.2 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain DUF853 PF05872.12 KIR64724.1 - 0.0048 15.5 0.0 0.037 12.6 0.0 2.3 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 KIR64724.1 - 0.0049 17.2 0.1 0.16 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T4SS-DNA_transf PF02534.14 KIR64724.1 - 0.023 13.5 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.7 KIR64724.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.14 KIR64724.1 - 0.16 11.9 0.1 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KIR64724.1 - 0.17 11.5 0.3 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KIR64724.1 - 0.27 11.1 0.0 25 4.7 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma70_r4_2 PF08281.12 KIR64726.1 - 6.5e-10 38.5 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 KIR64726.1 - 2.9e-08 33.1 0.0 6.8e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 KIR64726.1 - 3.2e-07 29.8 0.1 1.1e-06 28.1 0.1 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR64726.1 - 9.8e-06 25.2 0.1 0.00011 21.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r2 PF04542.14 KIR64726.1 - 0.00058 19.6 2.9 0.002 17.8 1.0 2.2 2 0 0 2 2 2 1 Sigma-70 region 2 HTH_29 PF13551.6 KIR64726.1 - 0.0031 17.5 1.0 0.019 15.0 0.4 2.6 2 1 0 2 2 2 1 Winged helix-turn helix HTH_AsnC-type PF13404.6 KIR64726.1 - 0.0036 17.1 0.3 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR64726.1 - 0.011 15.6 0.1 0.44 10.5 0.0 2.6 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain Sigma70_r3 PF04539.16 KIR64726.1 - 0.012 15.7 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-70 region 3 Terminase_5 PF06056.12 KIR64726.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_40 PF14493.6 KIR64726.1 - 0.015 15.7 0.1 0.12 12.8 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 KIR64726.1 - 0.021 14.6 0.0 0.077 12.8 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR64726.1 - 0.022 14.2 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 KIR64726.1 - 0.094 12.5 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_7 PF02796.15 KIR64726.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Phage_terminase PF10668.9 KIR64726.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage terminase small subunit Crp PF00325.20 KIR64726.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Glyco_hydro_10 PF00331.20 KIR64727.1 - 1.6e-102 342.9 0.0 2e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Ricin_B_lectin PF00652.22 KIR64727.1 - 7.6e-29 100.5 10.7 7.6e-29 100.5 10.7 2.7 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR64727.1 - 1.3e-25 89.9 25.9 1.2e-11 45.2 2.3 4.1 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like DUF4179 PF13786.6 KIR64727.1 - 0.062 13.8 0.3 0.23 11.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) ET PF01684.16 KIR64727.1 - 0.35 11.3 11.8 3.8 7.9 0.2 3.5 2 1 2 4 4 4 0 ET module HTH_3 PF01381.22 KIR64728.1 - 0.00065 19.7 0.0 0.0009 19.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR64728.1 - 0.0022 18.3 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_35 PF13693.6 KIR64728.1 - 0.0039 17.2 0.0 0.0046 17.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KIR64728.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_25 PF13413.6 KIR64728.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_25 PF13481.6 KIR64731.1 - 1.1e-14 54.5 0.1 1.8e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KIR64731.1 - 0.079 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Latarcin PF10279.9 KIR64731.1 - 0.31 11.5 2.0 3.3 8.2 1.8 2.3 2 0 0 2 2 2 0 Latarcin precursor Mso1_C PF14477.6 KIR64736.1 - 0.065 13.6 0.1 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 Membrane-polarising domain of Mso1 Pro-rich_19 PF15455.6 KIR64737.1 - 0.031 13.4 0.2 0.036 13.2 0.2 1.1 1 0 0 1 1 1 0 Proline-rich 19 SprT-like PF10263.9 KIR64739.1 - 5.2e-05 23.1 0.1 8.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Phage_holin_2_3 PF16080.5 KIR64744.1 - 0.14 12.0 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Resolvase PF00239.21 KIR64745.1 - 1.2e-19 70.9 0.6 3.1e-19 69.5 0.4 1.9 2 0 0 2 2 2 1 Resolvase, N terminal domain Zn_ribbon_recom PF13408.6 KIR64745.1 - 3.7e-10 40.2 0.4 7.4e-10 39.2 0.4 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Recombinase PF07508.13 KIR64745.1 - 5.8e-05 23.4 0.0 0.00022 21.6 0.0 2.0 1 0 0 1 1 1 1 Recombinase LysM PF01476.20 KIR64745.1 - 0.056 13.5 0.0 0.23 11.6 0.0 2.0 3 0 0 3 3 3 0 LysM domain HTH_Tnp_ISL3 PF13542.6 KIR64745.1 - 0.43 10.0 5.7 0.91 9.0 0.1 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 T2SSF PF00482.23 KIR64746.1 - 1.9e-16 60.1 3.2 3.7e-16 59.2 3.2 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F HATPase_c_2 PF13581.6 KIR64750.1 - 1.6e-24 86.2 0.3 1.9e-24 86.0 0.3 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4213 PF13938.6 KIR64750.1 - 0.072 13.3 0.2 0.58 10.4 0.1 2.4 1 1 1 2 2 2 0 Putative heavy-metal chelation H_PPase PF03030.16 KIR64751.1 - 5.5e-240 798.5 41.6 7.9e-240 797.9 41.6 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase RSN1_TM PF13967.6 KIR64751.1 - 0.055 13.2 0.1 3.4 7.4 0.1 3.0 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport EI24 PF07264.11 KIR64751.1 - 9.1 6.5 31.7 5.3e+02 0.7 15.3 5.3 2 1 1 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Topoisom_bac PF01131.20 KIR64754.1 - 5.6e-119 397.8 0.0 5.6e-119 397.8 0.0 1.6 2 0 0 2 2 2 1 DNA topoisomerase Toprim_C_rpt PF13368.6 KIR64754.1 - 4.3e-65 215.6 1.1 4.7e-18 64.9 0.1 4.7 3 1 1 4 4 4 4 Topoisomerase C-terminal repeat Toprim PF01751.22 KIR64754.1 - 8.9e-27 93.3 0.0 1.9e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 KIR64754.1 - 0.00013 22.4 1.1 0.00053 20.4 0.0 2.5 2 0 0 2 2 2 1 Toprim domain MarR_2 PF12802.7 KIR64754.1 - 0.01 15.7 1.8 0.23 11.4 0.1 3.8 4 0 0 4 4 4 0 MarR family SBP_bac_3 PF00497.20 KIR64754.1 - 0.026 13.9 0.0 0.026 13.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Toprim_2 PF13155.6 KIR64754.1 - 0.12 12.8 0.0 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 Toprim-like ALO PF04030.14 KIR64755.1 - 1.9e-72 244.2 0.0 2.4e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIR64755.1 - 1.4e-27 96.1 1.3 2e-27 95.6 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain HTH_53 PF18606.1 KIR64755.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Ala_racemase_N PF01168.20 KIR64756.1 - 1.2e-13 51.2 0.2 2.1e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ADH_N PF08240.12 KIR64756.1 - 0.097 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain YbaB_DNA_bd PF02575.16 KIR64757.1 - 9.6e-08 32.2 0.1 1.2e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Unstab_antitox PF09720.10 KIR64757.1 - 0.053 13.6 1.2 0.053 13.6 1.2 1.7 2 0 0 2 2 2 0 Putative addiction module component T7SS_ESX_EspC PF10824.8 KIR64758.1 - 0.00024 21.5 7.5 0.00058 20.3 7.5 1.6 1 1 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm PSP1 PF04468.12 KIR64760.1 - 3.7e-17 62.4 0.0 5.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region OAM_dimer PF16554.5 KIR64760.1 - 0.036 14.5 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase HupF_HypC PF01455.18 KIR64760.1 - 0.12 12.6 0.0 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 HupF/HypC family Metallophos PF00149.28 KIR64761.1 - 0.0078 16.7 0.0 0.015 15.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ABC2_membrane PF01061.24 KIR64761.1 - 1.3 8.4 5.0 0.3 10.5 0.4 2.0 1 1 1 2 2 2 0 ABC-2 type transporter Neurensin PF14927.6 KIR64762.1 - 0.0076 16.0 2.2 0.062 13.0 0.2 2.1 1 1 1 2 2 2 1 Neurensin CrgA PF06781.12 KIR64762.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein CrgA Herpes_gE PF02480.16 KIR64762.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3357 PF11837.8 KIR64762.1 - 2 8.9 7.3 0.45 11.0 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) T2SSM PF04612.12 KIR64764.1 - 0.001 19.2 0.5 0.0013 18.8 0.5 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M T3SSipB PF16535.5 KIR64764.1 - 0.0023 18.5 3.2 0.077 13.5 0.3 1.9 1 1 1 2 2 2 2 Type III cell invasion protein SipB DUF4407 PF14362.6 KIR64764.1 - 0.015 14.7 3.2 0.017 14.5 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 KIR64764.1 - 0.018 14.6 4.4 0.022 14.3 4.4 1.0 1 0 0 1 1 1 0 Intermediate filament protein Tropomyosin PF00261.20 KIR64764.1 - 0.03 13.7 7.0 0.034 13.5 7.0 1.0 1 0 0 1 1 1 0 Tropomyosin Borrelia_P83 PF05262.11 KIR64764.1 - 0.03 12.8 0.8 0.034 12.6 0.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_13 PF13166.6 KIR64764.1 - 0.031 12.9 0.9 0.035 12.8 0.9 1.0 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 KIR64764.1 - 0.039 14.5 4.3 0.045 14.3 4.3 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 KIR64764.1 - 0.32 11.2 4.4 0.47 10.7 0.9 2.3 1 1 2 3 3 3 0 Haemolysin XhlA DUF3584 PF12128.8 KIR64764.1 - 1.1 6.6 8.3 1.4 6.4 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Alanine_zipper PF11839.8 KIR64764.1 - 2 8.9 14.6 13 6.3 14.6 1.9 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF4240 PF14024.6 KIR64766.1 - 2.9e-10 40.4 1.4 1.6e-08 34.8 1.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4240) ADSL_C PF10397.9 KIR64766.1 - 0.16 12.6 1.2 19 5.9 0.2 2.6 2 1 0 2 2 2 0 Adenylosuccinate lyase C-terminus Acetyltransf_1 PF00583.25 KIR64767.1 - 1.1e-17 64.4 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR64767.1 - 8.1e-11 42.0 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR64767.1 - 2.2e-09 37.6 0.0 2.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR64767.1 - 2.6e-09 37.8 0.0 3.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR64767.1 - 8.8e-07 29.1 0.1 3.7e-06 27.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIR64767.1 - 0.0015 18.7 0.0 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR64767.1 - 0.002 18.0 0.1 0.0041 17.1 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KIR64767.1 - 0.0025 17.9 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KIR64767.1 - 0.21 11.3 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Putative_PNPOx PF01243.20 KIR64768.1 - 2.8e-15 56.3 0.0 4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2231 PF09990.9 KIR64769.1 - 8.4e-20 71.2 8.7 1.3e-19 70.5 8.7 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) HSP20 PF00011.21 KIR64770.1 - 2.7e-15 56.3 0.0 3.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIR64770.1 - 9.2e-08 31.5 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PfkB PF00294.24 KIR64771.1 - 6.2e-23 81.6 5.7 4.9e-10 39.2 6.6 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 KIR64771.1 - 1.8e-15 57.4 0.0 4.1e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like GAF PF01590.26 KIR64771.1 - 0.082 13.5 0.3 0.49 11.0 0.1 2.5 2 1 0 2 2 2 0 GAF domain DJ-1_PfpI PF01965.24 KIR64772.1 - 1.2e-51 174.8 0.0 1.3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 KIR64772.1 - 2.3e-05 24.1 0.0 3.2e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 C-terminal domain found in long catalases MctB PF11382.8 KIR64772.1 - 0.0079 15.9 0.1 0.11 12.2 0.1 2.1 2 0 0 2 2 2 1 Copper transport outer membrane protein, MctB GATase PF00117.28 KIR64772.1 - 0.098 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I MFS_1 PF07690.16 KIR64773.1 - 2.1e-52 178.2 60.5 1.8e-51 175.2 57.8 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIR64773.1 - 1.3e-16 60.2 24.4 1.7e-16 59.8 24.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIR64773.1 - 3.1e-12 46.1 9.6 3.1e-12 46.1 9.6 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KIR64773.1 - 0.023 13.0 14.7 0.2 9.9 2.0 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sigma70_r4_2 PF08281.12 KIR64773.1 - 0.14 11.9 0.3 0.45 10.2 0.3 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 NUDIX PF00293.28 KIR64774.1 - 3.8e-18 65.8 0.0 4.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KIR64774.1 - 0.021 14.8 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain AMP-binding PF00501.28 KIR64775.1 - 3.9e-92 309.1 0.0 5e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR64775.1 - 3.7e-20 72.7 3.9 2e-19 70.4 0.4 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 KIR64776.1 - 3.2e-20 72.4 2.1 5.6e-20 71.6 2.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR64776.1 - 4.2e-08 33.0 0.0 9e-07 28.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIR64776.1 - 1.7e-07 32.3 1.4 4.5e-07 31.0 1.4 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIR64776.1 - 0.0053 16.6 0.6 0.021 14.7 0.0 2.2 3 0 0 3 3 3 1 N-terminal domain of oxidoreductase DUF1970 PF09301.10 KIR64776.1 - 0.057 13.7 0.9 0.21 11.9 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) ADH_N PF08240.12 KIR64778.1 - 5.2e-29 100.3 0.4 8.1e-29 99.7 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KIR64778.1 - 3.3e-12 46.1 1.0 3.3e-12 46.1 1.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KIR64778.1 - 3.2e-10 40.1 0.3 1.8e-09 37.6 0.3 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIR64778.1 - 9.4e-06 25.1 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KIR64778.1 - 0.0017 17.9 0.1 0.0062 16.0 0.1 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIR64778.1 - 0.0048 17.9 0.0 0.008 17.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 KIR64778.1 - 0.0055 15.4 0.4 0.011 14.5 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KIR64778.1 - 0.015 14.7 0.3 0.023 14.0 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HAD_2 PF13419.6 KIR64779.1 - 7.3e-28 97.8 0.0 8.4e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR64779.1 - 7.1e-19 68.9 0.3 3.3e-18 66.7 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR64779.1 - 6.3e-10 39.0 0.2 1.2e-09 38.1 0.2 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIR64779.1 - 3.8e-06 27.4 0.2 6.7e-06 26.6 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FKBP_C PF00254.28 KIR64780.1 - 1.1e-20 73.8 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Protocadherin PF08374.11 KIR64780.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Putative_PNPOx PF01243.20 KIR64781.1 - 8.5e-19 67.5 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KIR64781.1 - 2.3e-11 43.8 0.0 2.9e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KIR64781.1 - 0.0018 17.9 0.0 0.0021 17.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like DUF447 PF04289.12 KIR64781.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF447) ABC_tran PF00005.27 KIR64782.1 - 2.8e-19 70.0 0.0 9e-10 39.2 0.0 4.1 3 1 0 3 3 3 3 ABC transporter AAA_29 PF13555.6 KIR64782.1 - 3.4e-06 26.7 1.0 0.022 14.5 0.0 2.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KIR64782.1 - 8.6e-06 25.3 0.0 4.4 6.7 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR64782.1 - 1.2e-05 25.8 2.6 0.17 12.2 0.2 3.2 4 0 0 4 4 4 2 AAA ATPase domain DnaJ_CXXCXGXG PF00684.19 KIR64782.1 - 1.7e-05 25.1 6.3 0.0095 16.3 0.3 3.3 3 0 0 3 3 3 2 DnaJ central domain RsgA_GTPase PF03193.16 KIR64782.1 - 3.8e-05 23.6 0.8 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KIR64782.1 - 0.00052 19.9 11.5 0.098 12.4 0.1 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KIR64782.1 - 0.00094 19.4 0.2 1.2 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIR64782.1 - 0.0031 17.3 0.0 6.1 6.5 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain UvrA_DNA-bind PF17755.1 KIR64782.1 - 0.0096 16.3 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 UvrA DNA-binding domain Anti-TRAP PF15777.5 KIR64782.1 - 0.011 15.6 6.0 6.3 6.8 1.3 3.5 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein NACHT PF05729.12 KIR64782.1 - 0.011 15.6 0.3 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KIR64782.1 - 0.012 16.2 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIR64782.1 - 0.03 13.9 1.1 7.8 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KIR64782.1 - 0.032 14.0 0.7 6.4 6.4 0.2 2.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIR64782.1 - 0.071 12.8 3.1 3.3 7.4 2.3 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TF_Zn_Ribbon PF08271.12 KIR64782.1 - 0.23 11.0 5.0 19 4.9 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding cobW PF02492.19 KIR64782.1 - 0.25 10.9 2.8 11 5.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 KIR64782.1 - 0.56 9.3 1.2 24 4.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) zinc_ribbon_9 PF14369.6 KIR64782.1 - 0.61 10.4 5.2 16 5.9 0.1 3.7 4 0 0 4 4 3 0 zinc-ribbon AAA_22 PF13401.6 KIR64782.1 - 0.64 10.3 2.7 24 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain zf-TFIIB PF13453.6 KIR64782.1 - 0.71 9.3 6.8 13 5.2 0.0 3.5 3 1 0 3 3 3 0 Transcription factor zinc-finger DUF2752 PF10825.8 KIR64782.1 - 1.4 9.0 4.4 1.8 8.7 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DUF2075 PF09848.9 KIR64782.1 - 1.7 7.8 4.5 9.2 5.4 1.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KIR64782.1 - 1.8 9.1 4.7 16 6.0 0.5 3.1 3 0 0 3 3 3 0 AAA domain F420H2_quin_red PF04075.14 KIR64783.1 - 6.7e-22 78.0 0.1 8.1e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 KIR64783.1 - 0.046 13.9 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Putative_PNPOx PF01243.20 KIR64783.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase TetR_C_1 PF02909.17 KIR64784.1 - 2.3e-19 69.7 0.0 3.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR64784.1 - 1.5e-08 34.2 0.2 3.7e-08 33.0 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 KIR64784.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR64784.1 - 0.088 12.6 1.3 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Ku PF02735.16 KIR64785.1 - 8.5e-42 143.2 0.0 1.3e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SRP-alpha_N PF04086.13 KIR64785.1 - 3.1 7.6 11.6 4.2 7.2 11.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4604 PF15377.6 KIR64785.1 - 4.6 7.6 17.1 6.4 7.2 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DNA_ligase_A_M PF01068.21 KIR64786.1 - 6.4e-27 94.5 0.0 3.3e-26 92.2 0.0 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KIR64786.1 - 2.5e-22 79.3 0.0 4.3e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 KIR64786.1 - 0.00066 19.7 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.19 KIR64786.1 - 0.048 13.5 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain RNA_ligase PF09414.10 KIR64786.1 - 0.054 13.8 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA ligase HD_6 PF18019.1 KIR64788.1 - 7e-43 147.0 0.5 1.3e-42 146.2 0.5 1.5 1 0 0 1 1 1 1 HD domain Cas3_C PF18395.1 KIR64788.1 - 3.3e-21 75.8 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 Cas3 C-terminal domain DEAD PF00270.29 KIR64788.1 - 1.3e-07 31.5 0.0 9.5e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR64788.1 - 0.0015 18.8 0.0 0.0064 16.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KIR64788.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CRISPR_Cse1 PF09481.10 KIR64789.1 - 1.7e-119 399.9 3.6 2e-119 399.7 3.6 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) CRISPR_Cse2 PF09485.10 KIR64790.1 - 2.9e-33 115.3 0.6 3.9e-33 115.0 0.6 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) Cas_CT1975 PF09344.10 KIR64791.1 - 1e-128 429.9 5.0 1.3e-128 429.6 5.0 1.0 1 0 0 1 1 1 1 CT1975-like protein Cas_Cas7 PF05107.12 KIR64791.1 - 0.00019 21.1 0.2 0.00069 19.2 0.2 1.7 1 1 0 1 1 1 1 CRISPR-associated protein Cas7 Cas_Cas5d PF09704.10 KIR64792.1 - 5.8e-48 163.6 0.1 6.7e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) Cas_Cas1 PF01867.16 KIR64793.1 - 3.6e-17 62.4 0.0 1e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 CRISPR associated protein Cas1 BCL9 PF11502.8 KIR64793.1 - 0.045 13.5 0.3 1.3 8.9 0.7 2.6 2 0 0 2 2 2 0 B-cell lymphoma 9 protein Phytase-like PF13449.6 KIR64794.1 - 1.3e-50 173.0 1.7 8.6e-46 157.2 0.1 3.5 3 0 0 3 3 3 2 Esterase-like activity of phytase SGL PF08450.12 KIR64794.1 - 0.067 12.8 0.0 19 4.7 0.0 3.1 4 0 0 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Me-amine-dh_H PF06433.11 KIR64794.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.5 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 KIR64794.1 - 0.13 10.8 0.0 0.28 9.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain CMD PF02627.20 KIR64796.1 - 8.8e-21 73.8 1.9 8.8e-21 73.8 1.9 1.7 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family WHAMM-JMY_N PF15920.5 KIR64796.1 - 0.07 13.0 0.1 0.47 10.4 0.0 2.2 2 1 1 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated Sigma70_r2 PF04542.14 KIR64797.1 - 2.1e-13 49.9 2.1 5.4e-13 48.5 2.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR64797.1 - 1.2e-12 47.3 0.0 2.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR64797.1 - 1.6e-08 33.9 1.1 5.9e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 KIR64797.1 - 7.2e-05 23.4 0.0 0.00024 21.7 0.0 1.9 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KIR64797.1 - 0.0008 19.8 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KIR64797.1 - 0.0086 16.3 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Sigma70_r3 PF04539.16 KIR64797.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 XhoI PF04555.13 KIR64798.1 - 9.8e-59 198.5 0.0 1.5e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease XhoI ERCC3_RAD25_C PF16203.5 KIR64799.1 - 1.8e-49 168.2 0.0 2.6e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KIR64799.1 - 2.6e-42 144.0 0.2 2.6e-42 144.0 0.2 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR64799.1 - 1e-12 48.4 0.0 1.6e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIR64799.1 - 1.2e-10 41.7 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIR64799.1 - 0.00035 19.4 0.0 0.0022 16.8 0.0 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 KIR64799.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase YkuD PF03734.14 KIR64800.1 - 3.2e-13 50.3 0.5 6.1e-13 49.4 0.5 1.5 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 KIR64800.1 - 4.4e-05 23.6 0.1 7.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF4253 PF14062.6 KIR64800.1 - 0.021 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) DUF202 PF02656.15 KIR64801.1 - 0.56 10.7 7.0 1.3 9.5 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) CcmD PF04995.14 KIR64801.1 - 0.84 9.8 9.6 4.8 7.4 3.0 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Helicase_C_3 PF13625.6 KIR64802.1 - 3.8e-39 133.7 0.1 1.5e-38 131.8 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WYL PF13280.6 KIR64802.1 - 0.00063 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 WYL domain RCDG1 PF15725.5 KIR64802.1 - 6.4 7.3 8.4 0.61 10.6 0.1 3.4 4 0 0 4 4 4 0 Renal cancer differentiation gene 1 protein HAD_2 PF13419.6 KIR64803.1 - 8.4e-15 55.3 0.0 3.1e-10 40.4 0.0 2.0 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64803.1 - 1.9e-14 54.5 0.7 4.1e-14 53.4 0.7 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR64803.1 - 1.2e-05 25.3 3.1 5.3e-05 23.2 3.1 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIR64803.1 - 0.00015 22.2 3.3 0.0026 18.1 3.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIR64803.1 - 0.027 14.6 0.0 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AA_kinase PF00696.28 KIR64803.1 - 0.032 13.8 0.2 0.044 13.4 0.2 1.1 1 0 0 1 1 1 0 Amino acid kinase family CSD PF00313.22 KIR64804.1 - 8.8e-14 51.1 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KIR64804.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain VitK2_biosynth PF02621.14 KIR64805.1 - 2.5e-90 302.6 0.0 2.8e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis MFS_1 PF07690.16 KIR64806.1 - 4.2e-12 45.7 29.6 4.2e-12 45.7 29.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3027 PF11228.8 KIR64807.1 - 1.3e-86 289.6 0.1 1.9e-86 289.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) MaoC_dehydrat_N PF13452.6 KIR64807.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase DrsE PF02635.15 KIR64807.1 - 0.14 12.5 0.1 0.21 11.9 0.1 1.2 1 0 0 1 1 1 0 DsrE/DsrF-like family DUF2530 PF10745.9 KIR64808.1 - 7.3e-11 42.2 0.8 1e-10 41.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) DUF2407_C PF13373.6 KIR64808.1 - 0.033 14.4 0.1 0.053 13.7 0.0 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain ATP-synt_J PF04911.12 KIR64808.1 - 0.18 11.4 0.5 0.31 10.7 0.5 1.4 1 0 0 1 1 1 0 ATP synthase j chain DUF4131 PF13567.6 KIR64808.1 - 0.26 10.9 3.5 0.33 10.6 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MFS_3 PF05977.13 KIR64809.1 - 6.7e-45 153.5 37.7 8e-45 153.2 37.7 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KIR64809.1 - 1e-20 74.0 53.1 3.8e-19 68.8 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KIR64811.1 - 4.2e-76 256.0 0.0 5.1e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3071 PF11268.8 KIR64812.1 - 8.1e-46 156.1 0.0 1.1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) Aminotran_5 PF00266.19 KIR64813.1 - 2.3e-16 59.7 0.0 7.5e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Citrate_synt PF00285.21 KIR64814.1 - 6.2e-87 292.0 0.0 4.3e-86 289.2 0.0 1.8 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain PNP_phzG_C PF10590.9 KIR64815.1 - 3e-20 72.0 2.6 6.3e-20 71.0 2.6 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KIR64815.1 - 2.2e-19 69.4 0.0 3.6e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MFS_3 PF05977.13 KIR64816.1 - 1.2e-34 119.6 42.8 1.5e-34 119.3 42.8 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 KIR64816.1 - 1.1e-18 67.3 61.9 2.8e-12 46.2 26.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldose_epim PF01263.20 KIR64817.1 - 4.5e-45 154.2 0.0 5.2e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Nitroreductase PF00881.24 KIR64818.1 - 3.2e-26 92.4 0.1 3.1e-25 89.2 0.1 2.1 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIR64818.1 - 4e-05 23.3 0.0 0.055 13.0 0.0 2.5 2 1 1 3 3 3 3 Putative TM nitroreductase Acyl-CoA_dh_1 PF00441.24 KIR64820.1 - 1.1e-32 113.3 1.0 1.7e-32 112.7 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR64820.1 - 5.1e-30 104.4 0.8 1.4e-29 103.0 0.2 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIR64820.1 - 2.5e-26 91.7 0.0 1.5e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIR64820.1 - 2.8e-10 40.6 0.1 4.9e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KIR64820.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal HxlR PF01638.17 KIR64821.1 - 5.3e-25 87.1 0.0 6.5e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 KIR64821.1 - 0.00091 19.2 0.2 0.0018 18.3 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.14 KIR64821.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KIR64821.1 - 0.0029 17.8 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 KIR64821.1 - 0.011 15.6 0.1 0.029 14.2 0.0 1.9 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KIR64821.1 - 0.015 15.2 0.9 0.085 12.8 0.4 2.2 2 1 0 2 2 2 0 MarR family MarR PF01047.22 KIR64821.1 - 0.029 14.3 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 MarR family LexA_DNA_bind PF01726.16 KIR64821.1 - 0.086 12.6 0.3 0.18 11.6 0.3 1.7 1 1 0 1 1 1 0 LexA DNA binding domain RecO_C PF02565.15 KIR64821.1 - 0.12 12.2 0.1 19 5.0 0.0 2.4 3 0 0 3 3 3 0 Recombination protein O C terminal Ribonuc_L-PSP PF01042.21 KIR64822.1 - 6.8e-17 61.6 0.0 8.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Hexapep PF00132.24 KIR64823.1 - 1.6e-10 40.3 3.9 1.1e-09 37.6 1.9 2.7 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIR64823.1 - 1.2e-07 31.3 1.5 6.2e-07 29.1 1.3 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4230 PF14014.6 KIR64824.1 - 7.8e-38 130.0 0.1 9.4e-38 129.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4230) RskA PF10099.9 KIR64824.1 - 0.22 11.8 4.0 0.17 12.2 3.0 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Big_3 PF07523.12 KIR64824.1 - 0.26 11.6 2.6 0.36 11.2 0.4 2.3 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) PspC PF04024.12 KIR64825.1 - 6.9e-19 67.4 0.6 7.8e-19 67.2 0.6 1.0 1 0 0 1 1 1 1 PspC domain SDH_alpha PF03313.15 KIR64826.1 - 3.7e-102 341.4 7.0 4.8e-102 341.1 7.0 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KIR64826.1 - 2.7e-59 200.0 0.0 7.6e-59 198.5 0.0 1.7 2 0 0 2 2 2 1 Serine dehydratase beta chain ABC_tran PF00005.27 KIR64827.1 - 1.8e-18 67.4 0.0 8.1e-18 65.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR64827.1 - 1.1e-05 25.0 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIR64827.1 - 1.8e-05 24.7 0.4 0.001 19.0 0.2 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR64827.1 - 0.0013 18.5 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR64827.1 - 0.0064 16.9 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIR64827.1 - 0.013 16.0 0.0 0.084 13.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIR64827.1 - 0.023 15.2 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIR64827.1 - 0.1 12.5 0.1 3 7.7 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KIR64827.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIR64827.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SCP1201-deam PF14428.6 KIR64827.1 - 0.23 11.3 0.0 0.5 10.2 0.0 1.5 1 0 0 1 1 1 0 SCP1.201-like deaminase GAGA PF09237.11 KIR64827.1 - 0.29 11.0 1.0 0.95 9.3 0.1 2.2 2 0 0 2 2 2 0 GAGA factor AAA_15 PF13175.6 KIR64827.1 - 0.3 10.7 0.0 0.41 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Glyphos_transf PF04464.14 KIR64828.1 - 9.6e-113 376.9 0.0 1.2e-112 376.6 0.0 1.1 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Glycos_transf_2 PF00535.26 KIR64828.1 - 1.4e-33 116.1 0.0 2.6e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR64828.1 - 7.7e-13 48.9 0.9 1.2e-12 48.3 0.2 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR64828.1 - 3.5e-08 33.3 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MazE_antitoxin PF04014.18 KIR64828.1 - 0.078 12.9 0.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Glyco_transf_21 PF13506.6 KIR64828.1 - 0.12 11.9 0.8 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KIR64828.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 KIR64829.1 - 6.7e-33 114.1 0.0 1.4e-32 113.1 0.0 1.5 2 0 0 2 2 1 1 ABC transporter OB_MalK PF17912.1 KIR64829.1 - 2.1e-07 31.7 0.0 8.4e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 KIR64829.1 - 2.4e-07 30.9 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR64829.1 - 0.00076 19.9 0.0 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR64829.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 KIR64829.1 - 0.0022 17.5 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR64829.1 - 0.0046 17.2 0.0 0.029 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIR64829.1 - 0.0058 16.6 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KIR64829.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain TOBE_2 PF08402.10 KIR64829.1 - 0.0096 16.1 0.5 0.14 12.3 0.2 2.8 2 0 0 2 2 2 1 TOBE domain AAA PF00004.29 KIR64829.1 - 0.14 12.6 0.1 0.36 11.3 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIR64829.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KIR64829.1 - 0.24 11.9 0.0 0.36 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIR64829.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 KIR64829.1 - 0.28 9.9 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein HTH_31 PF13560.6 KIR64832.1 - 1.3e-10 41.4 2.8 1.3e-10 41.4 2.8 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64832.1 - 0.005 16.9 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR64832.1 - 0.034 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pou PF00157.17 KIR64832.1 - 0.04 13.9 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain DUF397 PF04149.12 KIR64833.1 - 2.8e-25 88.1 1.5 3.1e-25 88.0 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Peptidase_M48 PF01435.18 KIR64834.1 - 3.8e-10 39.9 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KIR64834.1 - 0.0051 16.1 0.0 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 TMEM100 PF16311.5 KIR64834.1 - 0.7 9.5 3.0 3.2 7.4 0.3 2.6 2 0 0 2 2 2 0 Transmembrane protein 100 DUF4442 PF14539.6 KIR64836.1 - 2e-23 83.0 0.0 2.2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) DUF350 PF03994.14 KIR64836.1 - 0.028 14.6 1.0 0.028 14.6 1.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Hydrolase PF00702.26 KIR64837.1 - 1.2e-11 45.3 0.8 3.2e-11 43.9 0.8 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIR64837.1 - 3.8e-11 43.4 0.0 2.8e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR64837.1 - 0.00013 22.0 2.2 0.00022 21.2 0.8 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KIR64837.1 - 0.014 15.8 1.8 0.085 13.3 1.6 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIR64837.1 - 0.14 12.2 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 KIR64837.1 - 0.23 11.3 0.0 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Glyco_hydro_65m PF03632.15 KIR64838.1 - 2.4e-130 434.9 0.0 3e-130 434.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KIR64838.1 - 4.3e-62 209.7 0.0 2.9e-61 207.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 KIR64838.1 - 1.1e-16 60.4 2.1 2.2e-16 59.5 0.6 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain Atrophin-1 PF03154.15 KIR64839.1 - 4.2 5.5 8.8 4.2 5.5 8.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Thioredoxin PF00085.20 KIR64840.1 - 6.2e-24 84.0 0.0 7e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIR64840.1 - 6e-08 32.9 0.0 1.3e-06 28.7 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KIR64840.1 - 7.9e-07 29.5 0.1 1e-05 25.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KIR64840.1 - 1e-06 28.5 0.1 6.7e-06 25.9 0.1 1.8 1 1 1 2 2 2 1 Redoxin HyaE PF07449.11 KIR64840.1 - 5.1e-06 26.4 0.0 5.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 KIR64840.1 - 9.5e-06 25.5 0.0 1.9e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KIR64840.1 - 0.00034 20.7 0.1 0.00054 20.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KIR64840.1 - 0.0077 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KIR64840.1 - 0.0099 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 KIR64840.1 - 0.019 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.14 KIR64840.1 - 0.071 13.5 0.0 0.087 13.3 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Phosducin PF02114.16 KIR64840.1 - 0.085 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin DIM1 PF02966.16 KIR64840.1 - 0.089 12.6 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 Mitosis protein DIM1 MerR_1 PF13411.6 KIR64841.1 - 5e-19 68.2 0.0 8.9e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR64841.1 - 1.2e-16 60.1 3.1 2.1e-16 59.4 3.1 1.4 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KIR64841.1 - 7.6e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 MerR, DNA binding DLH PF01738.18 KIR64842.1 - 7.2e-07 29.0 0.0 8.9e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIR64842.1 - 4.8e-05 22.9 0.3 0.31 10.5 0.0 2.4 2 1 1 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIR64842.1 - 0.00027 20.3 0.2 0.17 11.1 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR64842.1 - 0.00055 19.6 0.0 0.00085 19.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KIR64842.1 - 0.0029 17.2 0.0 0.0049 16.5 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KIR64842.1 - 0.0034 17.3 0.0 0.012 15.6 0.0 1.7 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KIR64842.1 - 0.047 13.3 0.2 0.07 12.8 0.2 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 KIR64842.1 - 0.086 12.6 0.0 7.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Beta_helix_2 PF18835.1 KIR64842.1 - 0.13 12.0 0.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase MT0933_antitox PF14013.6 KIR64843.1 - 9.3e-18 64.3 10.4 1.1e-17 64.0 10.4 1.2 1 0 0 1 1 1 1 MT0933-like antitoxin protein Fer4_13 PF13370.6 KIR64844.1 - 2.5e-09 37.6 0.0 3.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KIR64844.1 - 4.5e-08 33.7 0.4 1.5e-07 32.0 0.4 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4 PF00037.27 KIR64844.1 - 0.025 14.4 0.6 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 KIR64844.1 - 0.053 13.6 0.0 0.091 12.9 0.0 1.4 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_2 PF12797.7 KIR64844.1 - 0.055 13.6 0.3 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KIR64844.1 - 0.11 12.6 0.6 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain DUF1232 PF06803.12 KIR64845.1 - 3.3e-05 23.6 8.4 3.3e-05 23.6 8.4 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1232) DUF2970 PF11174.8 KIR64845.1 - 0.048 13.5 7.3 0.061 13.2 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) VCBS PF13517.6 KIR64846.1 - 7.6e-36 122.5 23.4 2.9e-09 37.4 3.1 6.0 4 2 2 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KIR64846.1 - 2.5e-27 94.6 48.9 0.00014 21.9 3.0 7.6 7 0 0 7 7 7 7 FG-GAP repeat TcdB_toxin_midN PF12256.8 KIR64846.1 - 1.6e-07 30.9 21.8 0.054 12.8 0.1 6.6 2 2 5 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region SGP PF17228.2 KIR64846.1 - 0.00083 20.1 5.1 0.63 10.9 0.2 4.7 4 1 1 5 5 5 1 Sulphur globule protein BBS2_Mid PF14783.6 KIR64846.1 - 0.0013 18.8 0.7 18 5.4 0.0 4.8 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Dockerin_1 PF00404.18 KIR64846.1 - 0.021 15.0 16.7 6.2 7.1 0.0 6.5 7 0 0 7 7 7 0 Dockerin type I domain BBS1 PF14779.6 KIR64846.1 - 0.041 13.3 1.2 44 3.4 0.0 4.4 5 1 1 6 6 6 0 Ciliary BBSome complex subunit 1 PliI PF16743.5 KIR64846.1 - 0.1 12.4 10.6 3.1 7.6 0.0 5.2 4 3 3 7 7 7 0 Periplasmic lysozyme inhibitor of I-type lysozyme Itfg2 PF15907.5 KIR64846.1 - 1.3 7.9 7.0 51 2.8 0.1 4.7 5 1 0 5 5 5 0 Integrin-alpha FG-GAP repeat-containing protein 2 Inhibitor_I53 PF11714.8 KIR64847.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.1 3 0 0 3 3 3 0 Thrombin inhibitor Madanin FAP PF07174.11 KIR64848.1 - 0.0065 16.0 10.9 0.0081 15.7 10.9 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Lipocalin_2 PF08212.12 KIR64849.1 - 1.3e-37 128.9 0.0 1.6e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain FtsX PF02687.21 KIR64850.1 - 7.8e-05 23.1 0.3 7.8e-05 23.1 0.3 4.9 7 0 0 7 7 7 2 FtsX-like permease family DUF4574 PF15141.6 KIR64850.1 - 0.41 10.6 0.0 0.41 10.6 0.0 3.6 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PadR PF03551.14 KIR64851.1 - 1.7e-15 56.7 0.0 2.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 KIR64851.1 - 0.0031 18.2 3.2 0.0059 17.3 2.7 1.7 2 0 0 2 2 2 1 Virulence activator alpha C-term TrmB PF01978.19 KIR64851.1 - 0.015 15.2 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2384 PF09722.10 KIR64851.1 - 0.78 9.8 3.8 5.9 7.0 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) WXG100 PF06013.12 KIR64852.1 - 4.5e-08 33.2 1.4 9.9e-08 32.1 0.2 1.9 2 0 0 2 2 2 1 Proteins of 100 residues with WXG PPE PF00823.19 KIR64852.1 - 0.0076 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 PPE family Peptidase_M75 PF09375.10 KIR64852.1 - 0.051 13.0 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Imelysin DUF3138 PF11336.8 KIR64853.1 - 0.013 14.2 2.0 0.015 13.9 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Acyl-CoA_dh_C PF12806.7 KIR64853.1 - 0.061 13.5 3.4 1.1 9.5 1.1 2.1 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like TEX13 PF15186.6 KIR64853.1 - 0.094 12.4 0.2 0.2 11.3 0.0 1.5 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family EccE PF11203.8 KIR64854.1 - 1.3e-15 57.5 6.2 1.3e-15 57.5 6.2 3.5 3 1 0 3 3 3 1 Putative type VII ESX secretion system translocon, EccE Spherulin4 PF12138.8 KIR64854.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.1 1 0 0 1 1 1 0 Spherulation-specific family 4 YukD PF08817.10 KIR64855.1 - 3e-26 91.9 2.8 4.5e-25 88.1 0.4 3.2 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD FtsK_SpoIIIE PF01580.18 KIR64856.1 - 1.3e-93 312.8 0.0 2.9e-52 177.4 0.0 4.9 5 1 1 6 6 6 4 FtsK/SpoIIIE family AAA_16 PF13191.6 KIR64856.1 - 2.4e-12 47.6 4.2 0.0012 19.2 0.0 4.2 4 0 0 4 4 4 3 AAA ATPase domain NACHT PF05729.12 KIR64856.1 - 8e-10 38.9 0.0 0.2 11.6 0.0 4.5 3 2 0 3 3 3 3 NACHT domain AAA_22 PF13401.6 KIR64856.1 - 7.1e-09 36.1 0.0 0.012 15.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KIR64856.1 - 2.9e-06 27.6 0.5 0.3 11.2 0.3 3.2 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_29 PF13555.6 KIR64856.1 - 3.5e-06 26.7 0.1 0.098 12.4 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 KIR64856.1 - 3.7e-06 27.5 0.2 1 9.8 0.6 3.4 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 KIR64856.1 - 9.9e-05 22.7 0.0 0.21 11.9 0.0 3.7 4 0 0 4 4 3 1 AAA domain MMR_HSR1 PF01926.23 KIR64856.1 - 0.00042 20.4 0.4 0.18 11.9 0.1 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KIR64856.1 - 0.00045 20.4 0.0 2 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KIR64856.1 - 0.00099 19.1 0.0 8.2 6.3 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIR64856.1 - 0.0023 18.3 0.0 36 4.8 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 KIR64856.1 - 0.0026 17.4 3.2 0.35 10.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain Adeno_IVa2 PF02456.15 KIR64856.1 - 0.0035 16.2 0.0 0.75 8.5 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_23 PF13476.6 KIR64856.1 - 0.0047 17.5 0.0 4.6 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KIR64856.1 - 0.022 14.5 0.0 5.7 6.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 KIR64856.1 - 0.028 13.3 0.1 1.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 KIR64856.1 - 0.033 14.4 0.0 21 5.4 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 KIR64856.1 - 0.036 13.1 0.2 4 6.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIR64856.1 - 0.073 12.4 0.2 15 4.9 0.1 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KIR64856.1 - 0.088 12.1 0.1 7.4 5.8 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Viral_helicase1 PF01443.18 KIR64856.1 - 0.089 12.5 0.1 5.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 KIR64856.1 - 0.096 12.5 0.0 21 4.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 KIR64856.1 - 0.11 12.5 0.0 12 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF853 PF05872.12 KIR64856.1 - 0.13 10.8 0.2 0.26 9.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 KIR64856.1 - 0.14 12.7 0.1 27 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KIR64856.1 - 0.16 11.8 0.1 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KIR64856.1 - 0.27 10.7 0.0 25 4.3 0.0 2.4 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KIR64856.1 - 0.28 11.4 3.5 2.9 8.1 0.0 3.1 4 0 0 4 4 2 0 AAA domain DUF815 PF05673.13 KIR64856.1 - 0.35 10.0 0.9 7.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) YbaB_DNA_bd PF02575.16 KIR64857.1 - 2.6e-16 59.6 0.1 3.6e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF4407 PF14362.6 KIR64857.1 - 0.081 12.3 0.4 0.2 11.0 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) T2SSF PF00482.23 KIR64857.1 - 0.14 12.1 2.4 6.4 6.8 0.5 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F T7SS_ESX_EspC PF10824.8 KIR64858.1 - 0.011 16.2 0.0 0.015 15.8 0.0 1.1 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm NADHdh PF00146.21 KIR64859.1 - 0.0017 17.7 1.8 0.0026 17.1 1.8 1.2 1 0 0 1 1 1 1 NADH dehydrogenase Harakiri PF15196.6 KIR64859.1 - 0.02 15.3 1.0 0.034 14.6 0.2 1.8 2 0 0 2 2 2 0 Activator of apoptosis harakiri CbtB PF09489.10 KIR64859.1 - 0.24 11.6 4.9 0.71 10.0 0.0 3.1 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) S_4TM PF18159.1 KIR64859.1 - 1.3 8.2 4.1 0.49 9.7 1.6 1.4 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF1772 PF08592.11 KIR64860.1 - 0.19 12.1 4.8 0.21 11.9 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DsbD_2 PF13386.6 KIR64860.1 - 0.26 11.2 6.6 0.047 13.6 2.3 1.8 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF4051 PF13260.6 KIR64860.1 - 0.5 10.1 3.8 0.57 10.0 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF1700 PF08006.11 KIR64860.1 - 2.1 7.9 5.6 2.4 7.6 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4131 PF13567.6 KIR64860.1 - 3.3 7.3 7.1 14 5.3 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) WXG100 PF06013.12 KIR64861.1 - 7.4e-16 58.2 1.2 7.4e-16 58.2 1.2 1.4 1 1 0 1 1 1 1 Proteins of 100 residues with WXG Cor1 PF04803.12 KIR64861.1 - 0.022 15.0 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region T7SS_ESX_EspC PF10824.8 KIR64861.1 - 0.061 13.8 1.6 0.085 13.3 1.6 1.3 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm WXG100 PF06013.12 KIR64862.1 - 2.4e-12 46.9 0.8 2.8e-12 46.7 0.8 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.11 KIR64862.1 - 0.027 15.0 0.3 0.063 13.8 0.3 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal T7SS_ESX_EspC PF10824.8 KIR64862.1 - 0.037 14.5 0.3 0.06 13.8 0.3 1.3 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Ran-binding PF05508.11 KIR64862.1 - 0.049 12.6 0.1 0.051 12.5 0.1 1.0 1 0 0 1 1 1 0 RanGTP-binding protein Cas_Cas1 PF01867.16 KIR64862.1 - 0.068 12.3 0.1 0.081 12.0 0.1 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Gsf2 PF11055.8 KIR64862.1 - 0.1 11.4 0.1 0.1 11.3 0.1 1.0 1 0 0 1 1 1 0 Glucose signalling factor 2 ATG_C PF09333.11 KIR64863.1 - 0.15 12.4 0.4 0.25 11.7 0.4 1.3 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Atg14 PF10186.9 KIR64864.1 - 0.062 12.4 1.0 0.089 11.9 1.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1S3 PF15753.5 KIR64864.1 - 0.088 12.9 0.3 0.088 12.9 0.3 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Sec8_exocyst PF04048.14 KIR64864.1 - 0.17 11.8 0.2 0.17 11.8 0.2 1.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain LMBR1 PF04791.16 KIR64864.1 - 0.21 10.5 0.6 0.26 10.2 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KIR64864.1 - 2.1 8.9 12.9 0.14 12.7 2.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region EMC3_TMCO1 PF01956.16 KIR64864.1 - 5.2 6.8 5.2 1.2 8.9 0.2 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like YibE_F PF07907.11 KIR64865.1 - 1.4e-70 237.6 22.8 2.1e-70 237.0 22.8 1.3 1 0 0 1 1 1 1 YibE/F-like protein E1-E2_ATPase PF00122.20 KIR64866.1 - 1.6e-47 161.4 3.6 1.6e-47 161.4 3.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KIR64866.1 - 1.8e-45 155.8 7.5 4.2e-45 154.6 7.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64866.1 - 5e-07 30.3 2.5 1.7e-06 28.6 1.1 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR64866.1 - 4.3e-05 23.4 0.2 0.00025 20.9 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIR64866.1 - 0.01 15.9 0.4 2.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF2933 PF11666.8 KIR64867.1 - 0.32 11.1 5.6 0.64 10.1 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) Trns_repr_metal PF02583.17 KIR64868.1 - 5.4e-30 103.6 1.8 6.6e-30 103.3 1.8 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor YojJ PF10372.9 KIR64868.1 - 0.017 15.2 0.1 0.04 14.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus HMA PF00403.26 KIR64869.1 - 3.2e-15 56.3 0.3 3.5e-15 56.2 0.3 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain TusA PF01206.17 KIR64869.1 - 0.02 14.7 0.1 0.085 12.7 0.0 1.8 2 0 0 2 2 2 0 Sulfurtransferase TusA PCC_BT PF18140.1 KIR64869.1 - 0.11 12.9 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain DUF748 PF05359.11 KIR64870.1 - 0.0023 18.1 0.1 0.0039 17.4 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF748) YtkA PF13115.6 KIR64870.1 - 0.037 14.6 0.0 9.7 6.9 0.0 3.7 4 1 1 5 5 5 0 YtkA-like E1-E2_ATPase PF00122.20 KIR64871.1 - 7.2e-52 175.5 3.6 1.8e-51 174.3 3.6 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIR64871.1 - 7.3e-46 157.1 11.4 1.6e-45 156.0 11.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIR64871.1 - 1.9e-15 57.1 0.1 4.3e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIR64871.1 - 6.7e-06 26.0 0.5 1.4e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR64871.1 - 0.0095 16.4 1.9 0.021 15.3 0.6 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase CBP PF12192.8 KIR64871.1 - 7.9 6.8 8.0 10 6.4 1.5 3.7 3 0 0 3 3 3 0 Fungal calcium binding protein CsbD PF05532.12 KIR64872.1 - 4.9e-17 61.6 9.1 5.4e-17 61.4 9.1 1.0 1 0 0 1 1 1 1 CsbD-like DUF1993 PF09351.10 KIR64873.1 - 0.13 12.4 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) MLTD_N PF06474.12 KIR64873.1 - 0.48 10.7 3.5 0.99 9.6 3.5 1.6 1 0 0 1 1 1 0 MltD lipid attachment motif HTH_5 PF01022.20 KIR64874.1 - 1.1e-10 41.2 0.3 1.6e-10 40.7 0.3 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KIR64874.1 - 6.1e-09 35.8 7.0 1e-08 35.1 7.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR64874.1 - 1.1e-07 31.6 6.2 2.1e-07 30.7 6.2 1.5 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 KIR64874.1 - 0.00037 20.6 0.1 0.00055 20.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 KIR64874.1 - 0.00082 18.9 0.3 0.0015 18.0 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 KIR64874.1 - 0.0011 19.0 2.9 0.0011 19.0 2.9 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 KIR64874.1 - 0.0017 18.2 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_CodY PF08222.11 KIR64874.1 - 0.0021 17.5 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 CodY helix-turn-helix domain Acetyltransf_10 PF13673.7 KIR64874.1 - 0.0022 17.9 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RP-C PF03428.13 KIR64874.1 - 0.0046 16.6 0.5 0.0069 16.1 0.5 1.4 1 0 0 1 1 1 1 Replication protein C N-terminal domain MarR PF01047.22 KIR64874.1 - 0.0063 16.4 0.1 0.0094 15.9 0.1 1.4 1 1 0 1 1 1 1 MarR family Rrf2 PF02082.20 KIR64874.1 - 0.012 15.9 0.3 0.02 15.2 0.3 1.4 1 1 0 1 1 1 0 Transcriptional regulator Acetyltransf_7 PF13508.7 KIR64874.1 - 0.013 15.9 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_23 PF13384.6 KIR64874.1 - 0.015 15.1 2.0 0.015 15.1 2.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_41 PF14502.6 KIR64874.1 - 0.015 14.9 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 KIR64874.1 - 0.018 15.3 0.3 0.025 14.9 0.3 1.3 1 1 0 1 1 1 0 Transposase HTH_8 PF02954.19 KIR64874.1 - 0.018 14.8 1.5 0.018 14.8 1.5 1.6 2 0 0 2 2 1 0 Bacterial regulatory protein, Fis family HTH_10 PF04967.12 KIR64874.1 - 0.026 14.3 0.3 0.057 13.2 0.1 1.6 2 0 0 2 2 2 0 HTH DNA binding domain Fe_dep_repress PF01325.19 KIR64874.1 - 0.05 13.8 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain PadR PF03551.14 KIR64874.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family HxlR PF01638.17 KIR64874.1 - 0.089 12.7 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix GntR PF00392.21 KIR64874.1 - 0.11 12.2 2.3 0.22 11.2 2.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 KIR64874.1 - 0.18 11.7 4.7 1.5 8.6 4.7 2.3 1 1 0 1 1 1 0 IclR helix-turn-helix domain YCII PF03795.14 KIR64875.1 - 1.2e-15 57.6 0.1 1.5e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 YCII-related domain Ntox3 PF15536.6 KIR64875.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 1 0 1 1 1 0 Bacterial toxin 3 HATPase_c_2 PF13581.6 KIR64876.1 - 1.1e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Methyltransf_21 PF05050.12 KIR64877.1 - 1.3e-12 48.1 0.0 1.8e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Big_7 PF17957.1 KIR64878.1 - 4.8e-24 84.9 36.0 5.9e-07 30.2 6.7 7.0 5 1 0 5 5 5 5 Bacterial Ig domain Y_Y_Y PF07495.13 KIR64878.1 - 6.1e-09 35.7 0.1 0.0044 16.9 0.0 4.0 4 0 0 4 4 4 2 Y_Y_Y domain DUF5122 PF17164.4 KIR64878.1 - 3.9e-06 27.1 10.0 0.048 13.9 0.8 5.1 4 0 0 4 4 4 2 Domain of unknown function (DUF5122) beta-propeller DUF4625 PF15418.6 KIR64878.1 - 7.3e-05 23.0 0.0 0.82 9.9 0.0 4.4 4 1 1 5 5 5 2 Domain of unknown function (DUF4625) Big_3_4 PF13754.6 KIR64878.1 - 0.0022 17.7 0.1 2.5 7.9 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function PKD PF00801.20 KIR64878.1 - 1.1 9.1 18.6 5.2 7.0 0.1 5.8 5 0 0 5 5 5 0 PKD domain ABC_tran PF00005.27 KIR64880.1 - 1.4e-27 96.9 0.0 1.9e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR64880.1 - 1.9e-11 44.3 0.0 8.7e-05 22.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR64880.1 - 0.0001 22.9 0.0 0.00016 22.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR64880.1 - 0.00036 20.3 0.7 0.00055 19.7 0.2 1.8 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR64880.1 - 0.00044 19.9 0.2 0.00088 19.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR64880.1 - 0.0013 18.2 0.0 0.087 12.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 KIR64880.1 - 0.0029 17.8 0.0 0.014 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KIR64880.1 - 0.0043 16.8 0.0 3 7.5 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_27 PF13514.6 KIR64880.1 - 0.013 15.0 0.3 0.026 14.1 0.1 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIR64880.1 - 0.017 15.5 0.1 0.029 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MukB PF04310.12 KIR64880.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_28 PF13521.6 KIR64880.1 - 0.046 14.0 0.1 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KIR64880.1 - 0.058 12.2 0.2 0.97 8.2 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 KIR64880.1 - 0.063 13.7 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIR64880.1 - 0.13 12.5 0.1 0.44 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KIR64880.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KIR64880.1 - 0.14 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIR64880.1 - 0.19 11.6 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.8 KIR64880.1 - 0.41 8.1 0.6 0.55 7.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-HC2 PF13490.6 KIR64881.1 - 5.1e-05 23.4 0.5 0.00024 21.3 0.1 2.4 2 0 0 2 2 2 1 Putative zinc-finger DUF2368 PF10166.9 KIR64881.1 - 0.01 15.5 1.9 0.012 15.2 0.7 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Melibiase_2 PF16499.5 KIR64882.1 - 2.8e-76 256.4 0.9 3.8e-76 256.0 0.9 1.2 1 0 0 1 1 1 1 Alpha galactosidase A CBM_2 PF00553.19 KIR64882.1 - 1.7e-29 102.1 6.4 1.7e-29 102.1 6.4 3.0 3 0 0 3 3 3 1 Cellulose binding domain Melibiase_C PF17801.1 KIR64882.1 - 1.5e-16 60.2 0.1 5.1e-16 58.5 0.1 2.0 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIR64882.1 - 2.9e-10 39.6 0.0 5.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Melibiase DUF2505 PF10698.9 KIR64882.1 - 0.15 12.2 0.6 0.3 11.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Pyr_redox_2 PF07992.14 KIR64883.1 - 9.2e-20 71.0 3.6 1.4e-19 70.4 3.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 KIR64883.1 - 1.5e-17 64.0 0.8 7.2e-17 61.9 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64883.1 - 1.4e-13 51.3 0.0 4.7e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR64883.1 - 8.5e-11 42.5 0.1 2.4e-10 41.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain TPMT PF05724.11 KIR64883.1 - 2.7e-10 40.3 0.1 5.4e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 KIR64883.1 - 5.3e-09 36.1 0.0 9.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Lycopene_cycl PF05834.12 KIR64883.1 - 2.1e-07 30.3 5.2 0.0021 17.2 0.5 3.3 2 1 1 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIR64883.1 - 2.3e-07 30.3 2.4 2.3e-07 30.3 2.4 3.2 2 1 2 4 4 4 1 FAD binding domain Methyltransf_31 PF13847.6 KIR64883.1 - 3.6e-07 30.1 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR64883.1 - 1.5e-06 27.8 0.1 2.3e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain HI0933_like PF03486.14 KIR64883.1 - 2.4e-06 26.6 3.8 9.7e-05 21.2 0.3 3.3 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIR64883.1 - 9.7e-06 25.0 0.0 0.023 13.9 0.2 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR64883.1 - 6.7e-05 23.0 0.4 0.00025 21.2 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR64883.1 - 8.2e-05 22.3 4.5 8.2e-05 22.3 4.5 4.0 2 2 1 4 4 4 2 FAD dependent oxidoreductase TehB PF03848.14 KIR64883.1 - 0.0007 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NAD_binding_9 PF13454.6 KIR64883.1 - 0.00083 19.4 12.1 0.5 10.3 1.7 3.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding NodS PF05401.11 KIR64883.1 - 0.004 16.8 0.0 0.0085 15.7 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) FAD_binding_3 PF01494.19 KIR64883.1 - 0.0062 15.8 0.5 0.01 15.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIR64883.1 - 0.011 15.1 4.3 0.011 15.1 4.3 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR64883.1 - 0.012 16.2 1.1 0.4 11.3 0.2 3.0 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Ubie_methyltran PF01209.18 KIR64883.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family K_oxygenase PF13434.6 KIR64883.1 - 0.053 12.7 0.1 0.83 8.7 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 KIR64883.1 - 0.084 12.7 0.6 12 5.7 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIR64883.1 - 0.088 11.9 14.5 0.037 13.1 1.2 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A Methyltransf_15 PF09445.10 KIR64883.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.16 KIR64883.1 - 0.35 9.9 0.0 2.7 7.0 0.0 1.9 1 1 0 1 1 1 0 mRNA capping enzyme NAD_binding_7 PF13241.6 KIR64883.1 - 2.9 8.4 5.8 0.68 10.4 0.2 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KIR64883.1 - 3.5 6.4 6.3 1.6 7.5 0.2 2.7 3 0 0 3 3 3 0 Tryptophan halogenase PadR PF03551.14 KIR64884.1 - 2.8e-25 88.1 1.0 3.6e-25 87.7 1.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KIR64884.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.6 1 1 0 1 1 1 1 Winged helix DNA-binding domain ARGLU PF15346.6 KIR64885.1 - 0.023 14.6 0.6 0.031 14.1 0.6 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF2339 PF10101.9 KIR64885.1 - 0.097 11.2 44.6 0.13 10.8 44.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF916 PF06030.12 KIR64887.1 - 3.3e-05 23.9 0.0 5.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF916) fn3_5 PF06280.12 KIR64887.1 - 0.00076 20.2 0.4 0.0026 18.4 0.0 1.9 2 1 0 2 2 2 1 Fn3-like domain NPCBM_assoc PF10633.9 KIR64887.1 - 0.0023 18.1 5.2 0.0028 17.9 1.0 3.2 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.8 KIR64887.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase LEA_2 PF03168.13 KIR64887.1 - 0.19 12.3 2.5 0.78 10.3 0.2 2.6 1 1 2 3 3 3 0 Late embryogenesis abundant protein SoxY PF13501.6 KIR64888.1 - 0.063 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY Glyco_hydro_43 PF04616.14 KIR64889.1 - 7.8e-29 100.9 0.8 3.7e-28 98.7 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KIR64889.1 - 1.1e-22 80.6 1.5 1.1e-22 80.6 1.5 3.5 3 1 1 4 4 4 1 Carbohydrate binding module (family 6) CBM_4_9 PF02018.17 KIR64889.1 - 9e-22 77.8 1.8 9e-22 77.8 1.8 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain DUF5010_C PF18099.1 KIR64889.1 - 0.021 14.9 2.0 0.029 14.5 0.1 2.2 2 0 0 2 2 2 0 DUF5010 C-terminal domain GH43_C2 PF17851.1 KIR64890.1 - 8.8e-31 107.2 0.1 1.8e-30 106.2 0.1 1.5 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_43 PF04616.14 KIR64890.1 - 6.8e-29 101.1 0.5 1e-28 100.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_4_9 PF02018.17 KIR64890.1 - 6.3e-18 65.4 0.0 2e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_2 PF00553.19 KIR64891.1 - 2.5e-21 75.9 11.5 8e-21 74.3 11.5 1.9 1 0 0 1 1 1 1 Cellulose binding domain Peptidase_S9 PF00326.21 KIR64891.1 - 0.0091 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIR64891.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KIR64891.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 KIR64891.1 - 0.051 13.1 0.0 0.051 13.1 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KIR64891.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAM70 PF14967.6 KIR64891.1 - 0.33 10.4 2.8 0.59 9.6 2.8 1.4 1 0 0 1 1 1 0 FAM70 protein Slp PF03843.13 KIR64892.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family NPCBM_assoc PF10633.9 KIR64893.1 - 8.6e-06 25.9 2.6 2.5e-05 24.4 0.1 2.7 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Gram_pos_anchor PF00746.21 KIR64893.1 - 0.046 13.7 1.7 0.086 12.8 1.7 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF11 PF01345.18 KIR64893.1 - 0.57 10.5 10.2 0.046 14.0 4.4 2.3 3 1 0 3 3 3 0 Domain of unknown function DUF11 SBP_bac_5 PF00496.22 KIR64895.1 - 5e-83 279.1 0.1 7.3e-83 278.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KIR64896.1 - 2.4e-38 131.7 12.5 4.8e-38 130.7 12.5 1.5 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR64897.1 - 6.7e-24 84.6 8.0 6.7e-24 84.6 8.0 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Bac_export_2 PF01312.19 KIR64897.1 - 0.25 10.5 0.4 0.44 9.7 0.0 1.5 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF3482 PF11981.8 KIR64897.1 - 0.63 9.4 4.5 1 8.7 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ABC_tran PF00005.27 KIR64898.1 - 3.9e-19 69.5 0.0 5.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR64898.1 - 4.9e-16 59.0 0.3 9.3e-16 58.1 0.3 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR64898.1 - 8.8e-06 25.7 0.0 0.00056 19.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR64898.1 - 7.9e-05 23.1 1.0 0.00017 22.0 1.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR64898.1 - 0.00025 21.3 0.0 0.00083 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIR64898.1 - 0.0079 15.6 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KIR64898.1 - 0.017 14.5 0.1 0.047 13.1 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIR64898.1 - 0.045 13.3 0.6 0.37 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR64898.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIR64898.1 - 0.078 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR64898.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KIR64898.1 - 0.16 12.0 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KIR64899.1 - 3.6e-26 92.3 0.0 4.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR64899.1 - 2e-05 25.0 1.6 3.1e-05 24.4 1.6 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KIR64899.1 - 0.00025 21.0 0.0 0.055 13.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KIR64899.1 - 0.00099 19.1 0.1 0.062 13.2 0.0 2.7 2 1 1 3 3 3 1 NACHT domain AAA_22 PF13401.6 KIR64899.1 - 0.0012 19.1 0.0 0.0027 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIR64899.1 - 0.0017 18.9 0.1 0.045 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIR64899.1 - 0.0019 17.9 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KIR64899.1 - 0.0078 15.8 1.1 0.016 14.8 1.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR64899.1 - 0.012 15.8 0.2 0.02 15.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR64899.1 - 0.012 15.3 2.0 0.035 13.8 0.5 2.3 1 1 1 2 2 2 0 AAA domain SMC_N PF02463.19 KIR64899.1 - 0.016 14.7 0.0 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Cytidylate_kin PF02224.18 KIR64899.1 - 0.026 14.3 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 KIR64899.1 - 0.042 13.6 0.0 0.9 9.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KIR64899.1 - 0.047 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 KIR64899.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 KIR64899.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 KIR64899.1 - 0.15 11.7 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase MFS_1 PF07690.16 KIR64900.1 - 2.2e-50 171.6 55.3 4.4e-49 167.3 52.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIR64900.1 - 0.43 8.8 11.6 0.62 8.3 2.0 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Adeno_E3B PF03376.14 KIR64900.1 - 0.69 10.2 0.0 0.69 10.2 0.0 2.5 3 1 0 3 3 3 0 Adenovirus E3B protein Methyltransf_25 PF13649.6 KIR64901.1 - 2.5e-14 53.7 0.0 6.4e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64901.1 - 1.3e-10 41.7 0.0 3.6e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR64901.1 - 4.4e-09 36.3 0.0 5.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR64901.1 - 2.8e-08 33.8 0.0 4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KIR64901.1 - 3e-08 33.6 0.2 4.4e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 KIR64901.1 - 3e-08 34.3 0.0 6.1e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 KIR64901.1 - 3.6e-06 26.7 0.0 4.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KIR64901.1 - 9e-06 25.3 0.0 3.1e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain TehB PF03848.14 KIR64901.1 - 2.6e-05 23.7 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 KIR64901.1 - 0.015 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF4350 PF14258.6 KIR64901.1 - 0.12 12.9 0.0 0.98 9.9 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4350) Chorion_S16 PF05836.12 KIR64901.1 - 0.89 9.8 4.7 0.29 11.4 0.7 2.1 2 1 1 3 3 3 0 Chorion protein S16 HTH_3 PF01381.22 KIR64902.1 - 3.4e-16 59.0 0.3 4.9e-16 58.5 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR64902.1 - 4.8e-15 55.7 1.3 7.5e-15 55.0 1.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 KIR64902.1 - 4.3e-13 48.8 0.0 6.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 KIR64902.1 - 1.9e-10 41.0 0.1 3e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 KIR64902.1 - 7.5e-10 38.7 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR64902.1 - 1e-05 25.3 1.5 1.7e-05 24.6 1.5 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KIR64902.1 - 0.00021 20.8 0.8 0.00099 18.6 0.4 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR64902.1 - 0.00072 19.3 0.6 0.0015 18.3 0.6 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_37 PF13744.6 KIR64902.1 - 0.00099 19.0 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 KIR64902.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.5 1 1 0 1 1 1 1 HTH DNA binding domain MarR PF01047.22 KIR64902.1 - 0.0056 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 MarR family AraC_binding PF02311.19 KIR64902.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_11 PF08279.12 KIR64902.1 - 0.011 15.6 1.1 0.023 14.7 0.7 1.7 2 0 0 2 2 2 0 HTH domain HTH_AraC PF00165.23 KIR64902.1 - 0.012 15.7 0.1 0.025 14.7 0.0 1.6 2 0 0 2 2 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_5 PF01022.20 KIR64902.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family AbiEi_4 PF13338.6 KIR64902.1 - 0.017 15.2 0.2 0.038 14.2 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin MarR_2 PF12802.7 KIR64902.1 - 0.023 14.6 0.2 0.046 13.6 0.2 1.6 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 KIR64902.1 - 0.086 12.7 0.2 0.22 11.4 0.2 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR64902.1 - 0.091 12.2 0.2 0.18 11.2 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.21 KIR64902.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF4232 PF14016.6 KIR64902.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) HTH_35 PF13693.6 KIR64902.1 - 0.12 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 KIR64902.1 - 0.16 11.8 0.3 0.67 9.7 0.1 2.0 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Phage_AlpA PF05930.12 KIR64902.1 - 0.18 11.7 0.0 18 5.3 0.0 2.2 1 1 1 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Rrf2 PF02082.20 KIR64902.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PhyH PF05721.13 KIR64904.1 - 2e-10 41.3 0.0 3.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glycos_transf_1 PF00534.20 KIR64905.1 - 5.8e-36 123.6 0.0 8.5e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR64905.1 - 1.4e-26 93.5 0.0 2.9e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR64905.1 - 3e-22 79.4 0.2 6.4e-22 78.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIR64905.1 - 8.6e-21 75.0 4.7 8.6e-21 75.0 4.7 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 KIR64905.1 - 4.1e-12 46.3 0.0 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 KIR64905.1 - 1.9e-07 31.4 0.0 3.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pyr_redox PF00070.27 KIR64905.1 - 0.067 13.8 0.1 0.17 12.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 KIR64905.1 - 0.32 10.4 3.0 0.47 9.8 0.4 2.3 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme YjbR PF04237.13 KIR64906.1 - 1.7e-07 31.7 0.0 2.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 YjbR TetR_C_1 PF02909.17 KIR64907.1 - 1.9e-20 73.2 0.1 2.8e-20 72.6 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR64907.1 - 2.2e-08 33.7 0.3 9.4e-08 31.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_19 PF12844.7 KIR64907.1 - 0.037 14.0 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Lipase_GDSL_3 PF14606.6 KIR64909.1 - 1.3e-15 58.0 0.0 7.5e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 KIR64909.1 - 2.9e-08 34.3 0.2 9.5e-08 32.6 0.2 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CPBP PF02517.16 KIR64910.1 - 5.8e-12 45.8 8.4 9e-12 45.2 4.8 2.6 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease TetR_N PF00440.23 KIR64912.1 - 1.4e-08 34.3 0.7 2.3e-08 33.7 0.7 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 KIR64912.1 - 0.0081 16.4 3.5 0.0081 16.4 3.5 2.3 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal KfrA_N PF11740.8 KIR64912.1 - 0.025 15.2 0.5 0.23 12.2 0.1 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HTH_23 PF13384.6 KIR64912.1 - 0.43 10.4 3.6 2 8.3 0.6 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Metallophos PF00149.28 KIR64913.1 - 8.2e-08 33.0 0.5 2.1e-07 31.7 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR64913.1 - 9e-06 26.0 0.3 1.8e-05 25.0 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pentapeptide_4 PF13599.6 KIR64914.1 - 3.3e-20 72.0 2.9 1.7e-10 40.9 0.8 2.7 1 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KIR64914.1 - 3.4e-18 64.9 24.2 7.9e-10 38.2 1.7 4.3 3 2 2 5 5 5 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KIR64914.1 - 1.2e-12 47.8 20.8 4.2e-07 30.0 5.2 4.1 2 2 1 3 3 3 3 Pentapeptide repeats (9 copies) CfAFP PF05264.11 KIR64914.1 - 0.018 15.0 0.2 1.5 8.8 0.0 2.1 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Peptidase_A4 PF01828.17 KIR64914.1 - 0.1 12.0 0.2 0.86 9.0 0.1 2.1 1 1 1 2 2 2 0 Peptidase A4 family Epimerase PF01370.21 KIR64915.1 - 2.3e-20 73.1 0.0 3e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR64915.1 - 8.2e-14 51.9 0.1 4.4e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIR64915.1 - 2.6e-13 49.7 0.0 4.7e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KIR64915.1 - 8.3e-12 44.7 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIR64915.1 - 6.5e-07 29.1 0.1 3.8e-05 23.3 0.1 2.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIR64915.1 - 0.00014 21.5 0.1 0.00022 20.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KIR64915.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Glyco_trans_4_4 PF13579.6 KIR64915.1 - 0.011 16.2 1.4 0.011 16.2 1.4 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Polysacc_synt_2 PF02719.15 KIR64915.1 - 0.067 12.3 0.2 0.15 11.2 0.2 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ECH_1 PF00378.20 KIR64916.1 - 3.1e-30 105.3 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR64916.1 - 4.8e-10 39.5 0.0 9.8e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF99 PF01949.16 KIR64916.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF99 TetR_N PF00440.23 KIR64917.1 - 1.6e-15 56.6 0.1 3.5e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 KIR64917.1 - 1.2e-13 51.7 3.7 1.2e-13 51.7 3.7 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_16 PF17920.1 KIR64917.1 - 0.49 10.6 7.0 0.071 13.4 1.7 2.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 KIR64917.1 - 3.2 8.5 10.1 0.42 11.4 4.0 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF190 PF02641.15 KIR64918.1 - 1.4e-05 25.3 0.0 2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized ACR, COG1993 P-II PF00543.22 KIR64918.1 - 0.0049 17.4 0.0 0.006 17.2 0.0 1.1 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Glyco_transf_28 PF03033.20 KIR64920.1 - 7e-10 39.1 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIR64920.1 - 8.4e-05 21.5 0.1 0.00013 20.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIR64920.1 - 0.0004 20.4 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Peptidase_M17_N PF02789.17 KIR64920.1 - 0.1 12.5 0.2 0.32 10.9 0.2 1.8 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain MerR_1 PF13411.6 KIR64921.1 - 2.2e-12 46.9 0.1 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR64921.1 - 9.8e-12 44.5 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 KIR64921.1 - 6.4e-07 29.5 0.1 4.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Helix-turn-helix domain LAL_C2 PF18603.1 KIR64922.1 - 6e-16 58.4 0.2 2e-15 56.7 0.2 1.9 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 KIR64922.1 - 1.5e-10 40.9 0.0 5.6e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KIR64922.1 - 1.1e-09 38.5 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KIR64922.1 - 6.9e-08 32.5 0.0 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 KIR64922.1 - 1.7e-07 31.0 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIR64922.1 - 1.2e-05 25.1 0.0 6.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KIR64922.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KIR64922.1 - 0.00019 21.0 0.0 0.00061 19.3 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_N PF18130.1 KIR64922.1 - 0.0002 21.8 0.3 0.0048 17.4 0.2 2.6 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp_5 PF13549.6 KIR64922.1 - 0.024 14.1 0.0 0.059 12.8 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KIR64922.1 - 0.083 12.1 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Tautomerase_2 PF14552.6 KIR64923.1 - 2.4e-26 91.6 0.0 3e-25 88.1 0.0 1.9 1 1 1 2 2 2 2 Tautomerase enzyme Tautomerase PF01361.21 KIR64923.1 - 6.1e-13 48.5 0.0 3.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Cys_Met_Meta_PP PF01053.20 KIR64924.1 - 6.1e-06 25.0 0.0 9e-06 24.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme APH PF01636.23 KIR64925.1 - 1.7e-17 64.1 5.3 2.6e-17 63.6 5.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIR64925.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family OCD_Mu_crystall PF02423.15 KIR64926.1 - 1.3e-27 96.6 0.3 1.6e-27 96.3 0.3 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 KIR64926.1 - 0.056 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent STAT1_TAZ2bind PF12162.8 KIR64927.1 - 0.065 12.8 0.1 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain HEPN_SAV_6107 PF18726.1 KIR64927.1 - 0.29 11.7 5.7 0.42 11.2 0.5 2.8 2 0 0 2 2 2 0 SAV_6107-like HEPN Aminotran_1_2 PF00155.21 KIR64928.1 - 4.7e-23 81.9 0.0 7.8e-23 81.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIR64928.1 - 0.0062 15.4 0.0 0.014 14.2 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 KIR64928.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V MFS_1 PF07690.16 KIR64929.1 - 3.7e-26 91.9 39.4 4.9e-14 52.0 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIR64929.1 - 4.6e-23 81.4 29.5 5.7e-23 81.1 29.5 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 KIR64929.1 - 1.1e-08 34.4 5.4 1.6e-08 33.9 5.4 1.2 1 0 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 KIR64929.1 - 0.0035 16.3 12.1 0.0035 16.3 12.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter CP_ATPgrasp_2 PF14403.6 KIR64930.1 - 3.4e-05 22.9 0.0 8.6e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 KIR64930.1 - 0.0052 15.8 0.1 0.012 14.6 0.1 1.8 1 1 0 1 1 1 1 A circularly permuted ATPgrasp p450 PF00067.22 KIR64931.1 - 4.5e-22 78.4 0.0 8.4e-20 71.0 0.0 2.6 2 1 1 3 3 3 3 Cytochrome P450 DUF4140 PF13600.6 KIR64932.1 - 0.063 13.7 0.9 0.13 12.7 0.4 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4096 PF13340.6 KIR64933.1 - 1.1e-23 83.3 0.4 2.1e-23 82.3 0.4 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 KIR64933.1 - 2e-11 43.9 1.4 1.6e-10 41.0 1.4 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 KIR64933.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain PRiA4_ORF3 PF07929.11 KIR64934.1 - 8e-08 32.2 0.0 9.7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Phage_integrase PF00589.22 KIR64935.1 - 6e-20 71.7 0.1 8.7e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KIR64935.1 - 5.6e-06 26.5 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_4 PF14657.6 KIR64935.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain LAL_C2 PF18603.1 KIR64936.1 - 5.4e-16 58.5 2.6 1.2e-15 57.4 2.6 1.7 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 KIR64936.1 - 2.8e-08 33.5 0.0 6.8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KIR64936.1 - 2.6e-05 24.3 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIR64936.1 - 0.00042 20.1 0.0 0.0028 17.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_N PF18130.1 KIR64936.1 - 0.00058 20.4 0.1 0.0041 17.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp N-terminal domain CPSase_L_D2 PF02786.17 KIR64936.1 - 0.036 13.6 0.0 0.06 12.8 0.0 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain R2K_2 PF18299.1 KIR64936.1 - 0.11 12.4 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 Methyltransf_25 PF13649.6 KIR64937.1 - 8.4e-19 68.1 0.0 1.4e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64937.1 - 5.2e-16 59.1 0.1 9.1e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR64937.1 - 6.1e-16 58.7 0.0 8.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR64937.1 - 5.5e-12 45.7 0.0 6.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR64937.1 - 1.8e-10 41.4 0.0 3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR64937.1 - 1.5e-08 34.4 0.0 2.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KIR64937.1 - 4.1e-07 29.6 0.0 2.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KIR64937.1 - 5.9e-07 29.3 0.0 8.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 KIR64937.1 - 0.00037 20.5 0.0 0.0005 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KIR64937.1 - 0.0011 17.9 0.0 0.013 14.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) TPMT PF05724.11 KIR64937.1 - 0.0015 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Met_10 PF02475.16 KIR64937.1 - 0.0075 16.0 0.0 0.018 14.8 0.0 1.7 1 1 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 KIR64937.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KIR64937.1 - 0.044 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KIR64937.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 KIR64937.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Bin3 PF06859.12 KIR64937.1 - 0.17 12.5 0.0 2.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) MFS_1 PF07690.16 KIR64938.1 - 3.4e-16 59.1 36.2 3.6e-16 59.0 29.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR64938.1 - 0.0024 16.8 1.2 0.0046 15.9 0.0 1.9 2 1 0 3 3 3 1 MFS_1 like family DUF4079 PF13301.6 KIR64938.1 - 4.9 7.3 10.3 0.93 9.6 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Acyl-CoA_dh_2 PF08028.11 KIR64939.1 - 1.1e-18 67.7 7.2 1.1e-18 67.7 7.2 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KIR64939.1 - 1.4e-11 44.9 0.9 2.7e-11 43.9 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR64939.1 - 4.5e-05 23.6 0.1 0.00023 21.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Sod_Fe_C PF02777.18 KIR64940.1 - 4.6e-33 113.4 0.0 7.7e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIR64940.1 - 1.4e-28 99.2 0.0 2.8e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Phage_integrase PF00589.22 KIR64942.1 - 2.6e-05 24.1 0.0 6.2e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Phage integrase family HTH_17 PF12728.7 KIR64943.1 - 2.1e-07 31.0 0.1 2.5e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR64943.1 - 0.00014 21.6 0.2 0.00029 20.5 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KIR64943.1 - 0.00038 20.4 0.1 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 KIR64943.1 - 0.002 18.2 0.2 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KIR64943.1 - 0.049 13.8 0.1 0.17 12.1 0.0 1.7 1 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase DUF2637 PF10935.8 KIR64944.1 - 0.0008 19.3 7.8 0.0011 18.9 7.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2637) FtsK_SpoIIIE PF01580.18 KIR64945.1 - 1.2e-15 57.5 0.0 2.3e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KIR64945.1 - 0.00066 18.7 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KIR64945.1 - 0.0014 19.0 1.2 0.029 14.8 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF853 PF05872.12 KIR64945.1 - 0.026 13.1 0.2 0.099 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 KIR64945.1 - 0.059 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KIR64945.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UTRA PF07702.13 KIR64947.1 - 7.3e-18 64.8 0.1 1e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 KIR64947.1 - 3.1e-14 52.4 0.1 6.5e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 KIR64947.1 - 0.0083 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 KIR64947.1 - 0.014 15.3 0.3 0.049 13.5 0.1 2.0 2 0 0 2 2 2 0 MarR family Acetyltransf_3 PF13302.7 KIR64949.1 - 6e-27 95.0 0.1 7.9e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIR64949.1 - 6.2e-11 42.7 0.0 7.3e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR64949.1 - 7.1e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR64949.1 - 0.0013 18.4 0.0 0.0047 16.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR64949.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein HEAT_PBS PF03130.16 KIR64950.1 - 0.09 13.5 1.9 0.36 11.6 0.1 2.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DUF1932 PF09130.11 KIR64951.1 - 0.00072 19.5 0.9 5.9 6.9 0.1 3.6 3 1 0 3 3 3 2 Domain of unknown function (DUF1932) HNH_2 PF13391.6 KIR64951.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease Cob_adeno_trans PF01923.18 KIR64951.1 - 0.028 14.5 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Exonuc_VII_S PF02609.16 KIR64951.1 - 0.077 13.1 0.2 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit WXG100 PF06013.12 KIR64951.1 - 0.096 12.9 0.6 3.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DDE_3 PF13358.6 KIR64952.1 - 1.2e-15 57.5 0.0 2.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KIR64952.1 - 1.2e-13 51.4 1.3 1.2e-13 51.4 1.3 3.8 4 0 0 4 4 4 1 Homeodomain-like domain HTH_29 PF13551.6 KIR64952.1 - 6.2e-12 45.4 0.1 6.2e-12 45.4 0.1 3.2 4 0 0 4 4 4 1 Winged helix-turn helix HTH_28 PF13518.6 KIR64952.1 - 1.5e-07 31.4 3.3 1.4e-06 28.3 0.0 3.2 2 1 1 3 3 3 1 Helix-turn-helix domain DDE_Tnp_ISAZ013 PF07592.11 KIR64952.1 - 0.00018 20.6 0.0 0.0011 18.0 0.0 1.9 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain rve PF00665.26 KIR64952.1 - 0.00021 21.5 0.5 0.00094 19.4 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 KIR64952.1 - 0.0029 17.3 0.0 0.0029 17.3 0.0 4.0 4 1 1 5 5 5 1 Homeodomain-like domain HTH_33 PF13592.6 KIR64952.1 - 0.028 14.1 1.7 0.1 12.2 1.7 2.1 1 0 0 1 1 1 0 Winged helix-turn helix WH2 PF02205.20 KIR64954.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 WH2 motif Cellulase PF00150.18 KIR64956.1 - 3.4e-31 108.7 4.4 5.7e-31 108.0 4.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_2 PF00553.19 KIR64956.1 - 1.9e-29 101.9 15.5 1.9e-29 101.9 15.5 2.4 2 0 0 2 2 2 1 Cellulose binding domain Peripla_BP_3 PF13377.6 KIR64957.1 - 1.7e-28 100.0 1.5 5.2e-28 98.4 0.4 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR64957.1 - 6.4e-18 65.2 0.0 7.3e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Metallophos_2 PF12850.7 KIR64957.1 - 0.074 13.2 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain GyrI-like PF06445.15 KIR64958.1 - 2.3e-17 63.7 0.0 3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_18 PF12833.7 KIR64958.1 - 1.4e-16 60.5 1.5 2.3e-16 59.8 1.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cass2 PF14526.6 KIR64958.1 - 2.8e-12 47.0 0.0 3.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Integron-associated effector binding protein HTH_AraC PF00165.23 KIR64958.1 - 8.8e-07 28.9 0.0 0.00067 19.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family NAD_binding_10 PF13460.6 KIR64959.1 - 3.2e-23 82.6 4.4 5.2e-23 81.9 4.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR64959.1 - 2e-22 79.9 0.2 2.5e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KIR64959.1 - 2.1e-07 30.3 0.1 3.9e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KIR64959.1 - 2.2e-07 31.2 0.2 4.5e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIR64959.1 - 1.6e-05 24.5 0.5 4.4e-05 23.1 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIR64959.1 - 2.2e-05 24.5 1.4 7.8e-05 22.7 0.4 2.2 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 KIR64959.1 - 0.00085 18.5 2.1 0.015 14.4 0.1 2.8 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIR64959.1 - 0.0019 17.4 0.1 0.0041 16.3 0.1 1.6 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 KIR64959.1 - 0.0023 18.2 0.2 0.0053 17.0 0.2 1.7 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KIR64959.1 - 0.033 14.8 0.1 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 KIR64959.1 - 0.14 12.3 2.7 0.38 10.9 0.9 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus HxlR PF01638.17 KIR64960.1 - 8.1e-29 99.3 0.0 9.5e-29 99.1 0.0 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 KIR64960.1 - 0.00011 22.0 0.1 0.00017 21.4 0.1 1.2 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR64960.1 - 0.00019 21.3 0.2 0.00032 20.5 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR64960.1 - 0.0019 18.2 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_47 PF16221.5 KIR64960.1 - 0.0039 16.7 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix PadR PF03551.14 KIR64960.1 - 0.0051 16.8 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Rrf2 PF02082.20 KIR64960.1 - 0.035 14.5 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_12 PF08461.10 KIR64960.1 - 0.071 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_Crp_2 PF13545.6 KIR64960.1 - 0.08 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain CLP_protease PF00574.23 KIR64961.1 - 1.6e-76 256.3 0.0 1.8e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease DmpG_comm PF07836.11 KIR64961.1 - 0.044 13.3 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 DmpG-like communication domain GTP1_OBG PF01018.22 KIR64961.1 - 0.12 12.0 0.1 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 GTP1/OBG HTH_31 PF13560.6 KIR64962.1 - 3.1e-15 56.3 5.3 3.1e-15 56.3 5.3 3.2 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR64962.1 - 6e-14 51.8 0.2 1.1e-13 51.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR64962.1 - 1.8e-09 37.4 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR64962.1 - 5.7e-07 29.9 0.0 9.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 KIR64962.1 - 3.2e-05 23.7 1.0 0.00015 21.6 1.0 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR64962.1 - 0.015 15.3 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.21 KIR64962.1 - 0.035 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family UreF PF01730.16 KIR64962.1 - 0.11 13.1 0.9 0.21 12.2 0.1 1.8 2 0 0 2 2 2 0 UreF TrkA_N PF02254.18 KIR64963.1 - 2.8e-28 98.5 2.5 4.4e-28 97.9 2.5 1.3 1 0 0 1 1 1 1 TrkA-N domain Ion_trans_2 PF07885.16 KIR64963.1 - 2.3e-12 46.7 1.3 4e-12 45.9 1.3 1.3 1 0 0 1 1 1 1 Ion channel F420_oxidored PF03807.17 KIR64963.1 - 6.6e-05 23.4 1.3 0.00021 21.8 0.9 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KIR64963.1 - 0.01 16.1 0.8 0.045 14.0 0.7 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 KIR64963.1 - 0.023 14.7 2.2 0.17 11.8 0.0 2.7 2 1 0 3 3 3 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KIR64963.1 - 0.026 15.0 0.6 0.091 13.2 0.6 1.9 1 1 1 2 2 2 0 Putative NAD(P)-binding Toprim_4 PF13662.6 KIR64963.1 - 0.026 15.0 0.3 0.17 12.4 0.2 2.2 1 1 1 2 2 2 0 Toprim domain Ion_trans PF00520.31 KIR64963.1 - 0.043 13.0 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein AdoHcyase_NAD PF00670.21 KIR64963.1 - 0.063 13.3 0.1 0.18 11.9 0.1 1.9 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KIR64963.1 - 0.09 12.3 0.2 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PK_C PF02887.16 KIR64963.1 - 0.66 10.2 4.3 2.6 8.3 1.4 2.7 2 2 0 2 2 2 0 Pyruvate kinase, alpha/beta domain TPP_enzyme_C PF02775.21 KIR64964.1 - 2.5e-30 105.3 0.0 3.8e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IBR PF01485.21 KIR64964.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain POR_N PF01855.19 KIR64965.1 - 5e-53 180.2 0.0 7.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KIR64965.1 - 2.2e-24 86.5 0.0 3.5e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_N PF02776.18 KIR64965.1 - 1.2e-06 28.2 0.6 2e-06 27.5 0.6 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PFOR_II PF17147.4 KIR64965.1 - 0.00012 22.4 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Oxidored_q4 PF00507.19 KIR64966.1 - 1.6e-29 102.0 0.4 2.1e-29 101.6 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF2157 PF09925.9 KIR64966.1 - 0.064 13.0 9.6 0.11 12.3 0.2 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF2530 PF10745.9 KIR64966.1 - 0.13 12.5 3.4 0.25 11.6 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Gram_pos_anchor PF00746.21 KIR64966.1 - 5.2 7.1 7.4 22 5.1 0.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Pterin_bind PF00809.22 KIR64967.1 - 4.9e-66 222.9 0.3 5.8e-66 222.6 0.3 1.1 1 0 0 1 1 1 1 Pterin binding enzyme Polyketide_cyc2 PF10604.9 KIR64968.1 - 4.3e-13 49.8 4.0 4.9e-13 49.6 4.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR64968.1 - 0.035 14.3 0.0 0.043 14.0 0.0 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Adenine_glyco PF03352.13 KIR64969.1 - 4.2e-65 218.8 0.0 5.2e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Biotin_carb_N PF00289.22 KIR64969.1 - 0.15 12.6 0.0 0.43 11.1 0.0 1.9 1 1 0 1 1 1 0 Biotin carboxylase, N-terminal domain ECH_1 PF00378.20 KIR64971.1 - 5.7e-53 179.8 0.1 6.4e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR64971.1 - 4e-32 112.0 0.1 7e-32 111.2 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PaaX_C PF08223.11 KIR64972.1 - 3.6e-29 101.0 1.0 7.4e-29 99.9 1.0 1.6 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain PaaX PF07848.12 KIR64972.1 - 8.2e-18 64.4 0.0 1.4e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 PaaX-like protein AbiEi_4 PF13338.6 KIR64972.1 - 0.011 15.9 0.5 0.027 14.6 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin MarR_2 PF12802.7 KIR64972.1 - 0.056 13.3 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 MarR family Peptidase_M17 PF00883.21 KIR64973.1 - 4.6e-105 351.3 0.0 5.7e-105 351.0 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIR64973.1 - 8.2e-12 45.1 1.8 1.2e-11 44.5 0.3 2.1 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain Methyltransf_3 PF01596.17 KIR64974.1 - 6.5e-19 67.9 0.0 7.4e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIR64974.1 - 4e-15 56.7 0.1 6.3e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR64974.1 - 6.3e-07 30.0 0.2 1.8e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR64974.1 - 2.2e-05 25.0 0.3 7.1e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR64974.1 - 0.00038 20.3 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR64974.1 - 0.021 14.3 0.0 0.043 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Glu_dehyd_C PF16912.5 KIR64974.1 - 0.055 13.0 0.6 3.7 7.0 0.0 2.3 2 1 0 2 2 2 0 Glucose dehydrogenase C-terminus Methyltransf_16 PF10294.9 KIR64974.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TetR_N PF00440.23 KIR64974.1 - 2.5 8.0 7.8 55 3.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family Trypsin_2 PF13365.6 KIR64975.1 - 2.5e-32 112.9 7.5 2.5e-32 112.9 7.5 2.4 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 KIR64975.1 - 8.8e-17 61.2 0.3 7e-16 58.3 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 KIR64975.1 - 1.1e-13 51.5 0.6 1.9e-13 50.8 0.6 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 KIR64975.1 - 7e-11 41.8 0.0 2.3e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KIR64975.1 - 2.3e-05 24.7 0.1 9.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 KIR64975.1 - 0.023 13.4 7.0 0.36 9.4 0.2 2.5 2 1 1 3 3 3 0 Peptidase S46 DUF3394 PF11874.8 KIR64976.1 - 0.057 13.1 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) MoCF_biosynth PF00994.24 KIR64976.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Probable molybdopterin binding domain MttA_Hcf106 PF02416.16 KIR64976.1 - 0.11 11.8 0.2 0.24 10.8 0.2 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family ParA PF10609.9 KIR64977.1 - 7.4e-89 297.4 0.0 8.9e-89 297.2 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 KIR64977.1 - 3.2e-18 65.7 1.2 3.2e-18 65.7 1.2 2.1 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 KIR64977.1 - 2.4e-14 53.5 0.0 3.3e-13 49.8 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KIR64977.1 - 9.9e-09 35.4 0.8 1.6e-07 31.4 0.8 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KIR64977.1 - 7.9e-07 28.6 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KIR64977.1 - 4.7e-06 26.2 0.0 0.0013 18.3 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KIR64977.1 - 3.8e-05 23.6 0.8 0.095 12.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain CBP_BcsQ PF06564.12 KIR64977.1 - 0.00057 19.4 0.6 0.088 12.3 0.3 2.4 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KIR64977.1 - 0.0013 18.0 0.5 0.0025 17.1 0.2 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KIR64977.1 - 0.015 14.9 0.5 0.027 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KIR64977.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KIR64977.1 - 0.047 12.7 0.9 0.11 11.4 0.3 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 KIR64977.1 - 0.064 12.5 1.0 0.071 12.4 0.1 1.4 2 0 0 2 2 2 0 VirC1 protein Chorismate_synt PF01264.21 KIR64977.1 - 0.083 11.6 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Chorismate synthase APS_kinase PF01583.20 KIR64977.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase LpxK PF02606.14 KIR64977.1 - 0.15 11.1 0.6 0.38 9.8 0.2 1.8 1 1 1 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase DUF1003 PF06210.11 KIR64978.1 - 3.1e-39 133.3 0.2 3.1e-39 133.3 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) PhzC-PhzF PF02567.16 KIR64979.1 - 2.5e-49 168.3 0.0 2.8e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein HAD_2 PF13419.6 KIR64981.1 - 1.1e-12 48.4 0.0 2.2e-12 47.4 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR64981.1 - 5.3e-10 39.9 0.0 2.7e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR64981.1 - 1.5e-05 24.9 0.0 0.00021 21.3 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 KIR64981.1 - 0.02 15.3 0.2 0.032 14.6 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EamA PF00892.20 KIR64982.1 - 3e-21 76.0 34.2 8.7e-16 58.3 15.1 2.9 2 1 0 2 2 2 2 EamA-like transporter family GSK-3_bind PF05350.12 KIR64982.1 - 1 8.6 7.4 0.59 9.4 1.9 2.5 2 1 1 3 3 3 0 Glycogen synthase kinase-3 binding Meth_synt_2 PF01717.18 KIR64983.1 - 1.9e-07 30.7 0.0 3.6e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain adh_short PF00106.25 KIR64985.1 - 7.7e-25 87.5 0.0 1.1e-23 83.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR64985.1 - 1.3e-15 57.7 0.0 3.3e-15 56.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR64985.1 - 7.5e-06 26.0 0.1 1.1e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DAO PF01266.24 KIR64985.1 - 0.0014 18.3 1.0 0.002 17.8 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Epimerase PF01370.21 KIR64985.1 - 0.0033 16.9 0.0 0.0042 16.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 KIR64985.1 - 0.0099 15.9 0.9 0.016 15.2 0.3 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 NAD_binding_10 PF13460.6 KIR64985.1 - 0.055 13.3 1.6 0.11 12.4 0.9 1.7 1 1 0 2 2 2 0 NAD(P)H-binding ApbA PF02558.16 KIR64985.1 - 0.13 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KIR64985.1 - 0.13 11.3 0.8 0.26 10.3 0.8 1.7 1 1 0 1 1 1 0 FAD binding domain Eno-Rase_NADH_b PF12242.8 KIR64985.1 - 0.14 12.0 0.3 0.31 10.8 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_oxidored PF12831.7 KIR64985.1 - 0.23 10.8 1.7 0.33 10.2 1.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HpcH_HpaI PF03328.14 KIR64986.1 - 1.4e-44 151.9 0.0 1.8e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KIR64986.1 - 2e-08 33.8 0.0 0.00087 18.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Malate_synthase PF01274.22 KIR64986.1 - 0.0003 19.2 0.0 0.12 10.6 0.0 2.5 3 0 0 3 3 3 2 Malate synthase DUF4190 PF13828.6 KIR64987.1 - 1.2e-19 69.8 11.8 1.2e-19 69.8 11.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4190) adh_short_C2 PF13561.6 KIR64988.1 - 1.8e-55 188.1 3.8 2.1e-55 187.8 3.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR64988.1 - 8.8e-45 152.6 1.2 1.1e-44 152.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KIR64988.1 - 0.063 13.3 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIR64988.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIR64988.1 - 0.26 11.7 1.0 0.71 10.3 0.2 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF4190 PF13828.6 KIR64989.1 - 5.8e-17 61.2 1.3 5.8e-17 61.2 1.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4190) FA_desaturase PF00487.24 KIR64989.1 - 0.0088 15.9 0.0 0.012 15.5 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase COX8 PF02285.15 KIR64989.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.7 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII DUF2076 PF09849.9 KIR64989.1 - 2.1 8.3 4.4 2.2 8.2 4.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Acyl-CoA_dh_1 PF00441.24 KIR64990.1 - 2.9e-46 157.4 4.8 4.6e-46 156.7 4.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR64990.1 - 5.4e-32 110.8 0.6 1.3e-31 109.6 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIR64990.1 - 2.5e-19 69.3 0.1 5.3e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIR64990.1 - 3.8e-19 69.3 3.1 6.1e-19 68.6 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoA_binding_2 PF13380.6 KIR64991.1 - 5.2e-40 136.6 0.8 5.9e-40 136.4 0.8 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KIR64991.1 - 0.0041 17.8 0.0 0.0059 17.3 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain E3_binding PF02817.17 KIR64991.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain DUF393 PF04134.12 KIR64992.1 - 9.3e-16 59.2 0.1 1.1e-15 59.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 zf-FLZ PF04570.14 KIR64992.1 - 0.082 12.4 1.3 0.12 11.8 1.3 1.3 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 HSP70 PF00012.20 KIR64993.1 - 9.5e-21 73.6 0.0 2.6e-18 65.6 0.0 2.2 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KIR64993.1 - 0.01 14.7 0.1 0.063 12.1 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein FGGY_C PF02782.16 KIR64993.1 - 0.021 14.6 1.8 0.043 13.5 1.6 1.5 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KIR64993.1 - 0.042 13.4 2.1 5.3 6.5 0.3 2.4 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KIR64993.1 - 0.15 12.5 0.1 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 Cell division protein FtsA Dynamin_N PF00350.23 KIR64994.1 - 3.6e-09 36.9 0.0 1.6e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KIR64994.1 - 0.00023 21.2 0.0 0.00083 19.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3987 PF13148.6 KIR64994.1 - 0.007 15.4 3.5 2.2 7.2 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF3987) AAA_16 PF13191.6 KIR64994.1 - 0.0089 16.4 0.6 0.0089 16.4 0.6 3.7 3 2 0 3 3 3 1 AAA ATPase domain DUF2267 PF10025.9 KIR64994.1 - 0.012 15.8 1.0 0.012 15.8 1.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) RsgA_GTPase PF03193.16 KIR64994.1 - 0.019 14.9 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KIR64994.1 - 0.028 14.3 0.2 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 KIR64994.1 - 0.095 12.6 0.8 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MCM PF00493.23 KIR64994.1 - 0.098 11.7 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain NUC130_3NT PF08158.12 KIR64994.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.2 3 0 0 3 3 3 0 NUC130/3NT domain AAA_5 PF07728.14 KIR64994.1 - 0.13 12.3 0.7 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3006 PF11213.8 KIR64994.1 - 0.13 12.5 0.5 0.44 10.8 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) AAA_29 PF13555.6 KIR64994.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KIR64994.1 - 0.17 12.1 0.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF842 PF05811.13 KIR64994.1 - 0.33 10.6 1.6 0.5 10.1 0.5 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) AAA_33 PF13671.6 KIR64994.1 - 4.6 7.4 12.1 9.1 6.4 0.0 3.5 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KIR64995.1 - 9.8e-08 32.2 0.0 0.00042 20.4 0.0 2.2 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 KIR64995.1 - 6.3e-05 23.0 0.0 0.00048 20.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 KIR64995.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Thioredoxin PF00085.20 KIR64997.1 - 5.3e-26 90.6 0.0 6.2e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIR64997.1 - 1.8e-08 34.8 0.0 2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIR64997.1 - 1.5e-07 31.7 0.0 0.00012 22.3 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KIR64997.1 - 6.9e-05 22.6 0.0 8.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KIR64997.1 - 0.00013 21.7 0.0 0.11 12.2 0.0 2.1 1 1 1 2 2 2 2 Redoxin OST3_OST6 PF04756.13 KIR64997.1 - 0.0049 16.3 0.0 0.0055 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIR64997.1 - 0.022 15.0 0.0 0.039 14.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 KIR64997.1 - 0.065 13.2 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family TetR_C_20 PF17925.1 KIR64998.1 - 0.069 13.5 2.3 0.22 11.9 0.8 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SpoU_methylase PF00588.19 KIR64999.1 - 4.3e-24 85.3 0.0 5.1e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family bPH_2 PF03703.14 KIR65001.1 - 2.9e-13 49.8 0.0 4.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain Tom5 PF10642.9 KIR65001.1 - 0.24 11.5 1.7 4.5 7.4 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase Sigma70_r4_2 PF08281.12 KIR65002.1 - 7.5e-16 57.5 0.2 1.2e-15 56.9 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR65002.1 - 1.7e-12 46.6 0.6 2.8e-12 45.9 0.6 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR65002.1 - 5.9e-08 32.4 0.6 5.9e-08 32.4 0.6 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 GerE PF00196.19 KIR65002.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 KIR65002.1 - 0.035 14.0 0.2 0.051 13.5 0.2 1.2 1 0 0 1 1 1 0 ECF sigma factor PHP PF02811.19 KIR65004.1 - 2.4e-06 28.0 0.0 2.4e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 PHP domain Acyl-CoA_dh_N PF02771.16 KIR65004.1 - 0.0017 19.0 2.2 2.5 8.8 0.2 3.6 3 1 1 4 4 4 2 Acyl-CoA dehydrogenase, N-terminal domain DUF3052 PF11253.8 KIR65004.1 - 0.0029 17.5 0.1 0.63 10.0 0.0 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF3052) MarC PF01914.17 KIR65005.1 - 7.4e-49 165.9 12.8 8.4e-49 165.7 12.8 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein DUF998 PF06197.13 KIR65005.1 - 0.64 9.6 26.8 2 7.9 2.8 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF998) CPP1-like PF11833.8 KIR65005.1 - 4.7 6.8 8.7 0.18 11.5 1.0 2.1 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2236 PF09995.9 KIR65006.1 - 8.5e-52 176.6 15.7 1.1e-51 176.2 15.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) FUR PF01475.19 KIR65007.1 - 3e-22 79.0 0.0 3.3e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 KIR65007.1 - 0.0033 17.3 0.2 0.0066 16.3 0.0 1.7 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Nudix_N_2 PF14803.6 KIR65007.1 - 0.014 15.3 0.6 0.014 15.3 0.6 2.3 2 0 0 2 2 2 0 Nudix N-terminal DUF2551 PF10826.8 KIR65007.1 - 0.099 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) RcpC PF16976.5 KIR65010.1 - 0.007 16.4 0.3 0.015 15.4 0.3 1.6 1 1 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB NTP_transferase PF00483.23 KIR65012.1 - 6.9e-22 78.2 0.0 9.3e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR65012.1 - 4.4e-08 33.6 0.8 1.1e-07 32.4 0.8 1.9 1 1 1 2 2 2 1 MobA-like NTP transferase domain MoeA_N PF03453.17 KIR65013.1 - 4.6e-34 117.5 3.2 4.7e-34 117.4 0.7 2.0 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KIR65013.1 - 3e-23 82.1 0.2 5.2e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KIR65013.1 - 2.9e-11 43.4 0.0 8.3e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF3426 PF11906.8 KIR65013.1 - 0.083 13.1 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) Glyco_hydro_46 PF01374.18 KIR65014.1 - 0.029 14.0 1.7 0.04 13.6 1.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 FA_desaturase PF00487.24 KIR65014.1 - 0.91 9.3 4.2 0.27 11.0 1.0 1.8 2 1 0 2 2 2 0 Fatty acid desaturase Abhydrolase_1 PF00561.20 KIR65015.1 - 4.7e-20 72.3 1.3 1.5e-19 70.6 0.3 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR65015.1 - 2.1e-13 51.4 16.3 2.6e-13 51.1 16.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR65015.1 - 1.5e-05 24.4 0.4 2.1e-05 23.9 0.4 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIR65015.1 - 0.037 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase BTAD PF03704.17 KIR65016.1 - 7e-39 133.6 13.1 7e-39 133.6 13.1 3.7 4 1 0 4 4 4 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KIR65016.1 - 9.1e-08 32.1 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_2 PF07719.17 KIR65016.1 - 0.0074 16.3 2.4 0.088 13.0 0.7 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KIR65019.1 - 9.8e-23 80.6 0.0 1.7e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR65019.1 - 7e-18 65.1 0.0 1.4e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR65019.1 - 3.7e-17 62.7 0.0 5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65019.1 - 1.5e-09 38.5 0.0 2.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR65019.1 - 1.9e-09 37.2 0.0 3.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIR65019.1 - 6.1e-09 35.8 0.0 8.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIR65019.1 - 0.0046 16.3 0.0 0.006 15.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KIR65019.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase UDPGT PF00201.18 KIR65021.1 - 7.8e-22 77.7 0.0 1.1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase p450 PF00067.22 KIR65022.1 - 6.9e-29 100.9 0.0 7.4e-19 67.8 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 AMP-binding PF00501.28 KIR65023.1 - 2.7e-189 629.1 0.0 1e-102 343.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KIR65023.1 - 3.8e-91 306.1 0.0 6.1e-48 163.6 0.0 2.8 2 1 0 2 2 2 2 Condensation domain Thioesterase PF00975.20 KIR65023.1 - 5.2e-31 108.5 0.0 1.6e-29 103.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KIR65023.1 - 2.7e-28 98.1 0.1 6.2e-15 55.3 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR65023.1 - 1.1e-17 64.7 0.2 1.4e-08 35.6 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Abhydrolase_1 PF00561.20 KIR65023.1 - 0.0035 17.0 0.1 0.0066 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tri3 PF07428.11 KIR65023.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 HTH_8 PF02954.19 KIR65023.1 - 0.17 11.7 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family adh_short PF00106.25 KIR65024.1 - 5.7e-40 136.9 0.0 7.5e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR65024.1 - 4.5e-30 104.9 0.0 5.9e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIR65024.1 - 2.5e-10 40.2 0.0 2.8e-08 33.5 0.0 2.0 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.10 KIR65024.1 - 2.8e-06 27.3 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4352 PF11611.8 KIR65025.1 - 3.1e-06 27.5 0.0 4.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) DUF1942 PF09167.11 KIR65025.1 - 0.078 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) VIT1 PF01988.19 KIR65025.1 - 0.085 12.7 0.1 0.085 12.7 0.1 1.4 2 0 0 2 2 2 0 VIT family 4PPT_N PF17837.1 KIR65026.1 - 6.7e-23 80.6 2.5 1.1e-22 79.9 2.5 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 KIR65026.1 - 5.7e-10 39.3 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PMT PF02366.18 KIR65028.1 - 1.7e-25 90.0 4.5 1.7e-25 90.0 4.5 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIR65028.1 - 1.5e-21 76.9 1.1 1.5e-21 76.9 1.1 3.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 KIR65028.1 - 1.4e-05 25.3 5.8 1.4e-05 25.3 5.8 4.9 5 3 0 5 5 5 2 Dolichyl-phosphate-mannose-protein mannosyltransferase OCC1 PF15506.6 KIR65028.1 - 1.8 8.8 7.1 22 5.3 0.1 2.4 2 0 0 2 2 2 0 OCC1 family TP_methylase PF00590.20 KIR65029.1 - 3.7e-30 105.5 2.9 6.1e-30 104.8 2.9 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_1g PF09334.11 KIR65030.1 - 2.7e-148 493.9 0.0 3.3e-148 493.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIR65030.1 - 4.3e-16 58.3 0.6 4e-08 32.0 0.1 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KIR65030.1 - 3e-09 36.6 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KIR65030.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 KIR65030.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) zf-ribbon_3 PF13248.6 KIR65030.1 - 2.6 7.6 6.2 4.9 6.7 0.5 2.2 1 1 0 2 2 2 0 zinc-ribbon domain Abhydrolase_1 PF00561.20 KIR65031.1 - 6.7e-30 104.6 0.0 1.1e-28 100.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR65031.1 - 6.3e-27 95.6 2.6 7.4e-27 95.4 2.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR65031.1 - 7.5e-21 74.5 0.0 9.7e-20 70.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR65031.1 - 0.0019 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF915 PF06028.11 KIR65031.1 - 0.0042 16.5 0.0 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 KIR65031.1 - 0.013 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 KIR65031.1 - 0.027 14.2 0.8 0.15 11.7 0.1 2.1 1 1 1 2 2 2 0 PGAP1-like protein Peptidase_S15 PF02129.18 KIR65031.1 - 0.059 13.0 0.1 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.10 KIR65031.1 - 0.074 12.1 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.12 KIR65031.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 KIR65031.1 - 0.17 11.7 0.0 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.15 KIR65031.1 - 0.22 10.7 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 KIR65031.1 - 0.25 10.8 0.0 0.69 9.4 0.0 1.8 1 1 0 1 1 1 0 Lipase (class 2) GHMP_kinases_C PF08544.13 KIR65033.1 - 1.2e-07 31.9 3.3 1.5e-07 31.7 2.1 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KIR65033.1 - 4.1e-07 30.2 2.1 1.7e-06 28.2 2.1 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain ABC_tran PF00005.27 KIR65034.1 - 3.6e-51 173.3 0.0 5.4e-25 88.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIR65034.1 - 1.2e-20 74.6 1.9 1.4e-05 25.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 KIR65034.1 - 4.4e-09 36.5 13.3 4.4e-09 36.5 13.3 2.1 2 0 0 2 2 2 1 ABC transporter C-terminal domain AAA_16 PF13191.6 KIR65034.1 - 7.8e-08 32.9 5.8 8.5e-05 23.0 0.2 3.2 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 KIR65034.1 - 1.3e-07 31.3 0.0 1.2 8.6 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR65034.1 - 3.4e-07 30.3 0.1 0.014 15.5 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_13 PF13166.6 KIR65034.1 - 2.4e-06 26.6 2.0 0.045 12.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain ABC_tran_Xtn PF12848.7 KIR65034.1 - 4.8e-06 26.5 2.3 0.00014 21.8 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIR65034.1 - 5.8e-06 25.9 0.2 0.027 14.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR65034.1 - 1.9e-05 24.9 1.1 0.12 12.6 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIR65034.1 - 4.1e-05 24.1 0.4 1.1 9.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 KIR65034.1 - 7.2e-05 23.1 3.3 0.044 14.0 0.1 3.5 3 1 0 3 3 3 1 AAA domain MeaB PF03308.16 KIR65034.1 - 9.1e-05 21.6 2.1 0.014 14.4 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KIR65034.1 - 0.00013 22.6 10.7 0.83 10.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain Arf PF00025.21 KIR65034.1 - 0.00016 21.2 0.7 0.13 11.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIR65034.1 - 0.00024 21.0 0.3 0.68 9.8 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase NACHT PF05729.12 KIR65034.1 - 0.00087 19.2 0.0 0.38 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KIR65034.1 - 0.0015 18.1 0.4 0.82 9.2 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIR65034.1 - 0.0019 18.4 2.6 0.23 11.6 0.0 3.4 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.6 KIR65034.1 - 0.0033 17.6 0.7 10 6.4 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KIR65034.1 - 0.0097 16.0 0.8 3.4 7.7 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 KIR65034.1 - 0.013 15.3 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Wbp11 PF09429.10 KIR65034.1 - 0.016 15.6 2.6 0.051 14.0 2.6 1.8 1 0 0 1 1 1 0 WW domain binding protein 11 Roc PF08477.13 KIR65034.1 - 0.017 15.3 0.0 6.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KIR65034.1 - 0.017 14.4 0.0 2.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 KIR65034.1 - 0.018 14.2 0.1 4.6 6.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 KIR65034.1 - 0.022 14.5 0.0 7.7 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 KIR65034.1 - 0.024 12.2 14.0 0.026 12.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 KIR65034.1 - 0.024 15.1 3.4 0.059 13.9 3.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region MobB PF03205.14 KIR65034.1 - 0.027 14.4 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TMF_TATA_bd PF12325.8 KIR65034.1 - 0.042 14.1 2.5 0.099 12.9 2.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_30 PF13604.6 KIR65034.1 - 0.047 13.4 11.6 0.65 9.7 0.2 3.6 3 2 0 3 3 3 0 AAA domain DLIC PF05783.11 KIR65034.1 - 0.062 12.1 1.0 1.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) ATP-synt_ab PF00006.25 KIR65034.1 - 0.066 12.9 0.0 9.1 5.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain dNK PF01712.19 KIR65034.1 - 0.069 13.0 0.3 6.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Med21 PF11221.8 KIR65034.1 - 0.087 13.1 1.2 0.21 11.8 1.2 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex AAA_27 PF13514.6 KIR65034.1 - 0.089 12.4 4.9 2.8 7.5 0.0 3.6 3 1 1 4 4 4 0 AAA domain Dynamin_N PF00350.23 KIR65034.1 - 0.098 12.7 0.0 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 KIR65034.1 - 0.1 12.6 0.1 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KIR65034.1 - 0.11 12.0 2.4 4 7.0 0.0 2.5 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KIR65034.1 - 0.13 12.7 0.5 24 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KIR65034.1 - 0.2 11.7 0.3 20 5.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain YlqD PF11068.8 KIR65034.1 - 0.25 11.7 1.7 0.42 11.0 1.7 1.3 1 0 0 1 1 1 0 YlqD protein PduV-EutP PF10662.9 KIR65034.1 - 0.25 11.1 0.7 4.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF724 PF05266.14 KIR65034.1 - 0.4 10.5 2.0 0.63 9.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-H PF05837.12 KIR65034.1 - 0.91 10.0 5.0 2.2 8.7 5.0 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 KIR65034.1 - 4.6 7.1 10.0 0.45 10.3 3.2 2.6 2 1 1 3 3 3 0 Septum formation initiator Thymidylate_kin PF02223.17 KIR65034.1 - 6.4 6.4 6.1 13 5.4 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase DUF4383 PF14325.6 KIR65035.1 - 1.9e-09 37.8 16.3 2.2e-09 37.6 16.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF4383 PF14325.6 KIR65036.1 - 4.5e-19 68.9 17.2 5.2e-19 68.7 17.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF308 PF03729.13 KIR65036.1 - 0.001 19.3 16.0 0.64 10.4 8.9 3.1 2 1 1 3 3 3 3 Short repeat of unknown function (DUF308) CD20 PF04103.15 KIR65036.1 - 0.003 17.6 6.9 0.003 17.6 6.9 1.5 2 0 0 2 2 2 1 CD20-like family DUF4199 PF13858.6 KIR65036.1 - 1.6 9.1 9.4 0.77 10.1 6.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DUF2700 PF10912.8 KIR65036.1 - 2.3 8.2 9.2 4.2 7.4 6.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2700) DUF2892 PF11127.8 KIR65036.1 - 3.9 7.6 22.8 3.8 7.6 3.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2892) FA_desaturase PF00487.24 KIR65037.1 - 3.8e-17 63.0 26.0 3.8e-17 63.0 26.0 2.2 1 1 1 2 2 2 1 Fatty acid desaturase TMEM169 PF15052.6 KIR65037.1 - 0.24 11.5 2.8 0.6 10.2 0.7 2.2 2 0 0 2 2 2 0 TMEM169 protein family Pribosyltran_N PF13793.6 KIR65038.1 - 7.7e-42 141.9 0.0 2.9e-41 140.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIR65038.1 - 5.4e-28 98.3 0.4 3.4e-27 95.7 0.1 2.3 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIR65038.1 - 2.6e-19 69.3 0.4 1.6e-18 66.8 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIR65038.1 - 1.1e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_L25p PF01386.19 KIR65039.1 - 6.6e-25 87.4 0.0 2.3e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 KIR65039.1 - 3.4e-19 69.0 2.2 9.3e-19 67.6 2.2 1.8 2 0 0 2 2 2 1 Ribosomal protein TL5, C-terminal domain PARM PF17061.5 KIR65039.1 - 0.026 14.7 2.4 0.035 14.3 2.4 1.1 1 0 0 1 1 1 0 PARM Pept_tRNA_hydro PF01195.19 KIR65040.1 - 4.8e-55 186.1 0.0 5.5e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Inositol_P PF00459.25 KIR65041.1 - 8e-27 94.4 0.2 2.6e-26 92.7 0.2 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family PAPS_reduct PF01507.19 KIR65042.1 - 1.4e-48 165.2 0.0 1.7e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 KIR65042.1 - 0.055 13.2 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 KIR65042.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC GalKase_gal_bdg PF10509.9 KIR65043.1 - 5.3e-22 77.1 1.0 2.1e-21 75.2 0.1 2.4 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KIR65043.1 - 1.6e-17 63.7 0.1 3.9e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KIR65043.1 - 4e-16 59.0 4.2 5.2e-16 58.6 1.6 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain Epimerase PF01370.21 KIR65044.1 - 1.9e-48 165.0 0.0 2.3e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65044.1 - 1.8e-41 142.7 0.0 2.7e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR65044.1 - 3.1e-11 42.8 0.0 4.4e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIR65044.1 - 5.3e-10 38.9 0.1 9.9e-10 38.0 0.1 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIR65044.1 - 7.9e-08 31.8 0.4 3e-06 26.6 0.4 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KIR65044.1 - 1.2e-07 31.8 0.2 1.9e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR65044.1 - 2.2e-05 24.1 0.6 0.00026 20.6 0.6 2.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIR65044.1 - 0.00048 19.4 0.2 0.3 10.2 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein KR PF08659.10 KIR65044.1 - 0.0076 16.2 0.8 0.066 13.1 0.4 2.2 1 1 1 2 2 2 1 KR domain adh_short PF00106.25 KIR65044.1 - 0.023 14.2 0.3 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIR65044.1 - 0.053 13.1 0.3 0.087 12.4 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KIR65044.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CBS PF00571.28 KIR65045.1 - 3.6e-17 62.6 6.2 6.2e-08 33.0 1.1 4.3 2 1 1 3 3 3 2 CBS domain CorC_HlyC PF03471.17 KIR65045.1 - 6.5e-17 61.3 0.0 6.8e-15 54.9 0.0 2.6 2 0 0 2 2 2 1 Transporter associated domain DUF4129 PF13559.6 KIR65045.1 - 0.34 11.2 0.2 0.34 11.2 0.2 4.6 4 2 0 4 4 4 0 Domain of unknown function (DUF4129) tRNA-synt_1b PF00579.25 KIR65046.1 - 5.7e-81 272.1 0.0 7.2e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Eno-Rase_NADH_b PF12242.8 KIR65046.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3775 PF12616.8 KIR65046.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) baeRF_family2 PF18844.1 KIR65046.1 - 0.16 12.0 1.4 0.68 10.0 0.3 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 2_5_RNA_ligase2 PF13563.6 KIR65047.1 - 3.7e-19 69.1 0.6 4.3e-19 68.9 0.6 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIR65047.1 - 4.3e-12 46.1 0.9 1.8e-05 24.8 0.2 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase Virul_fac_BrkB PF03631.15 KIR65048.1 - 2.6e-35 122.3 23.4 3.1e-35 122.1 23.4 1.0 1 0 0 1 1 1 1 Virulence factor BrkB PHO4 PF01384.20 KIR65048.1 - 5.7 5.9 8.3 0.65 9.0 3.9 1.6 2 0 0 2 2 2 0 Phosphate transporter family Multi_Drug_Res PF00893.19 KIR65050.1 - 1.3e-29 102.7 8.5 1.5e-29 102.5 8.5 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 KIR65050.1 - 0.00018 21.7 11.8 0.00021 21.5 11.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family Oxidored_FMN PF00724.20 KIR65051.1 - 1.8e-76 257.7 0.0 2.1e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIR65051.1 - 0.016 14.7 1.1 3.3 7.1 0.1 2.9 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Alpha-amylase PF00128.24 KIR65052.1 - 7e-82 275.7 0.0 1.4e-81 274.7 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 KIR65052.1 - 2.6e-11 43.7 2.1 4.1e-11 43.1 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 KIR65052.1 - 0.00065 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KIR65052.1 - 0.056 12.5 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Peripla_BP_3 PF13377.6 KIR65053.1 - 2.6e-39 135.2 1.8 4e-39 134.6 0.4 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR65053.1 - 1.4e-19 70.6 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR65053.1 - 5.3e-13 48.5 0.1 1.2e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR65053.1 - 1.7e-07 31.1 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR65053.1 - 0.0015 18.8 0.8 0.0015 18.8 0.8 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KIR65053.1 - 0.037 13.8 0.6 0.2 11.5 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_26 PF13443.6 KIR65053.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain SBP_bac_8 PF13416.6 KIR65054.1 - 3.2e-43 148.6 8.1 4.7e-43 148.0 8.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR65054.1 - 1.4e-30 107.4 12.5 1.4e-30 107.4 12.5 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR65054.1 - 5.1e-06 26.4 4.3 1.3e-05 25.0 4.0 1.9 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein TM_PBP2_N PF16296.5 KIR65055.1 - 1.3e-36 124.6 0.7 2.3e-36 123.8 0.1 1.8 2 0 0 2 2 2 1 N-terminal of TM subunit in PBP-dependent ABC transporters BPD_transp_1 PF00528.22 KIR65055.1 - 5.5e-18 65.3 17.2 5.5e-18 65.3 17.2 2.2 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component MalF_P2 PF14785.6 KIR65055.1 - 0.044 13.8 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain BPD_transp_1 PF00528.22 KIR65056.1 - 2.3e-18 66.6 20.3 2.3e-18 66.6 20.3 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3096 PF11295.8 KIR65056.1 - 0.045 13.4 0.8 0.045 13.4 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) TetR_N PF00440.23 KIR65057.1 - 1.5e-18 66.3 0.0 2.7e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 KIR65057.1 - 1.6e-12 47.7 1.1 1.6e-12 47.7 1.1 1.7 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 KIR65057.1 - 8.1e-11 42.2 1.2 8.1e-11 42.2 1.2 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_31 PF17940.1 KIR65057.1 - 0.0017 18.6 4.5 0.0017 18.6 4.5 2.5 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_14 PF17754.1 KIR65057.1 - 0.014 15.3 0.7 0.63 10.0 0.1 2.6 2 1 0 2 2 2 0 MftR C-terminal domain TetR_C_21 PF17926.1 KIR65057.1 - 0.097 12.8 0.4 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ferritin PF00210.24 KIR65057.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain DUF5353 PF17304.2 KIR65058.1 - 0.1 12.4 1.4 0.24 11.2 1.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5353) CPP1-like PF11833.8 KIR65058.1 - 0.66 9.6 3.4 0.5 10.0 0.4 1.9 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Cyd_oper_YbgE PF09600.10 KIR65058.1 - 2.1 8.8 10.3 1.3 9.5 0.8 2.5 2 1 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Bmp PF02608.14 KIR65059.1 - 6.6e-55 186.2 5.0 3e-54 184.1 5.0 1.8 1 1 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like ABC_tran PF00005.27 KIR65060.1 - 1.5e-48 164.8 0.0 3.3e-28 98.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR65060.1 - 4.7e-07 29.9 0.2 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR65060.1 - 0.00059 19.5 0.1 0.018 14.8 0.0 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR65060.1 - 0.0067 16.3 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KIR65060.1 - 0.0088 15.8 0.5 0.038 13.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR65060.1 - 0.064 13.7 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIR65060.1 - 0.078 12.4 0.0 2.6 7.4 0.0 2.5 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR65060.1 - 0.099 12.7 0.0 0.4 10.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase MukB PF04310.12 KIR65060.1 - 0.13 12.0 0.2 0.72 9.6 0.0 2.2 3 0 0 3 3 3 0 MukB N-terminal Dynamin_N PF00350.23 KIR65060.1 - 0.13 12.3 0.0 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KIR65060.1 - 0.16 11.6 0.0 0.65 9.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain BPD_transp_2 PF02653.16 KIR65061.1 - 3.1e-43 147.9 37.7 4.7e-43 147.3 32.4 2.1 2 0 0 2 2 2 2 Branched-chain amino acid transport system / permease component SLC3A2_N PF16028.5 KIR65061.1 - 0.048 13.2 0.5 0.18 11.4 0.5 1.9 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus BPD_transp_2 PF02653.16 KIR65062.1 - 4e-36 124.6 34.6 4e-36 124.6 34.6 2.2 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component PsbL PF02419.17 KIR65062.1 - 0.081 12.9 2.5 0.27 11.3 2.5 1.9 1 0 0 1 1 1 0 PsbL protein DUF4212 PF13937.6 KIR65062.1 - 0.74 10.2 0.0 0.74 10.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) dCMP_cyt_deam_1 PF00383.23 KIR65064.1 - 1.5e-11 44.1 0.1 3.7e-11 42.8 0.1 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KIR65064.1 - 3.3e-09 37.1 0.1 1.6e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Glycos_transf_3 PF00591.21 KIR65065.1 - 1.3e-33 116.6 0.9 1.9e-33 116.2 0.9 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 KIR65065.1 - 3.8e-20 71.3 0.8 4.6e-19 67.9 0.0 2.8 3 0 0 3 3 3 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 KIR65065.1 - 9e-18 63.9 0.2 9e-18 63.9 0.2 2.3 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain DUF4272 PF14094.6 KIR65066.1 - 5.3e-43 146.7 0.0 6.1e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4272) A_deaminase PF00962.22 KIR65067.1 - 8.4e-88 294.8 0.0 1e-87 294.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase PRK PF00485.18 KIR65068.1 - 4.1e-05 23.4 0.0 0.0027 17.5 0.0 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 KIR65068.1 - 0.015 15.6 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIR65068.1 - 0.04 13.6 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR65068.1 - 0.045 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIR65068.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR65068.1 - 0.085 12.8 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KIR65068.1 - 0.12 12.7 3.6 0.76 10.1 3.6 2.3 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 KIR65068.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 KIR65068.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KIR65068.1 - 0.23 10.7 0.5 0.49 9.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NIT PF08376.10 KIR65069.1 - 2.4e-37 129.6 11.8 2.4e-37 129.6 11.8 2.7 2 1 0 2 2 2 1 Nitrate and nitrite sensing HATPase_c PF02518.26 KIR65069.1 - 2.9e-10 40.6 0.0 5.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR65069.1 - 8.4e-09 35.7 0.0 6.9e-08 32.7 0.0 2.7 1 1 0 1 1 1 1 HAMP domain DUF4407 PF14362.6 KIR65069.1 - 0.0025 17.2 1.3 0.0025 17.2 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Keratin_B2_2 PF13885.6 KIR65069.1 - 0.026 14.5 4.0 0.21 11.6 4.0 2.1 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein KorB_C PF06613.11 KIR65069.1 - 0.12 12.3 0.5 0.85 9.6 0.0 2.4 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Robl_LC7 PF03259.17 KIR65070.1 - 1.1e-22 79.5 0.2 1.7e-22 79.0 0.2 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF2173 PF09941.9 KIR65070.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) ATP_bind_1 PF03029.17 KIR65071.1 - 2.2e-30 106.3 1.4 7.6e-29 101.2 1.4 2.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KIR65071.1 - 0.00033 20.6 0.8 0.018 15.0 1.3 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIR65071.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 KIR65071.1 - 0.0046 16.6 0.4 0.041 13.5 0.4 2.3 2 1 0 2 2 2 1 Ras family Roc PF08477.13 KIR65071.1 - 0.016 15.5 0.2 0.08 13.2 0.2 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KIR65071.1 - 0.028 14.2 0.2 0.064 13.0 0.3 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KIR65071.1 - 0.035 13.6 0.1 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 KIR65071.1 - 0.091 12.4 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 KIR65071.1 - 0.13 12.3 0.2 0.19 11.8 0.2 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 KIR65071.1 - 0.17 11.8 1.5 0.29 11.1 1.5 1.4 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 KIR65071.1 - 0.21 10.6 1.0 0.3 10.1 1.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 KIR65071.1 - 1.8 8.8 5.5 0.54 10.5 1.3 2.1 2 1 0 2 2 2 0 AAA domain DUF2722 PF10846.8 KIR65073.1 - 0.55 9.1 4.4 0.86 8.5 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PadR PF03551.14 KIR65074.1 - 3.7e-23 81.3 0.1 4.6e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KIR65074.1 - 9e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 KIR65074.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 KIR65074.1 - 0.016 15.7 0.1 0.035 14.6 0.1 1.6 1 1 0 1 1 1 0 Winged helix DNA-binding domain DUF1380 PF07128.12 KIR65075.1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Cyt_bd_oxida_II PF02322.15 KIR65076.1 - 1.9e-64 217.9 33.9 2.2e-64 217.7 33.9 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Cyt_bd_oxida_I PF01654.17 KIR65077.1 - 4e-111 371.6 38.3 6.2e-90 301.8 19.6 2.0 1 1 0 2 2 2 2 Cytochrome bd terminal oxidase subunit I UPF0220 PF05255.11 KIR65077.1 - 0.34 10.4 0.1 0.34 10.4 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0220) COX14 PF14880.6 KIR65077.1 - 0.86 9.5 0.0 0.86 9.5 0.0 2.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Peptidase_M48 PF01435.18 KIR65078.1 - 4.2e-12 46.3 0.1 7.9e-12 45.4 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 KIR65078.1 - 4.5e-06 26.1 0.0 6.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 Penicillinase_R PF03965.16 KIR65079.1 - 2e-21 76.5 0.0 2.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 KIR65079.1 - 0.00015 21.5 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 KIR65079.1 - 0.0089 15.8 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 2 1 LexA DNA binding domain RPA_C PF08784.11 KIR65079.1 - 0.012 16.3 0.0 0.02 15.5 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal PaaX PF07848.12 KIR65079.1 - 0.019 15.2 1.4 0.15 12.3 0.2 2.1 2 0 0 2 2 2 0 PaaX-like protein MarR_2 PF12802.7 KIR65079.1 - 0.025 14.4 2.0 0.12 12.3 0.6 2.5 2 1 0 2 2 2 0 MarR family GntR PF00392.21 KIR65079.1 - 0.044 13.4 0.6 0.14 11.8 0.7 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR PF01047.22 KIR65079.1 - 0.046 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 MarR family Aldedh PF00171.22 KIR65080.1 - 6e-32 110.7 5.1 1.2e-31 109.7 5.1 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DeoC PF01791.9 KIR65081.1 - 2e-27 96.4 0.2 2.6e-27 96.0 0.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 KIR65081.1 - 0.15 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase UPRTase PF14681.6 KIR65082.1 - 3.5e-59 199.7 0.0 4e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIR65082.1 - 3.6e-10 39.6 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GPP34 PF05719.11 KIR65083.1 - 5e-44 150.8 8.9 5.7e-44 150.6 8.9 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PGM_PMM_I PF02878.16 KIR65084.1 - 1.5e-35 121.9 0.0 3.1e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KIR65084.1 - 3.4e-25 88.7 0.1 2e-24 86.2 0.2 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIR65084.1 - 4.3e-18 65.6 0.0 7.8e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KIR65084.1 - 8.7e-09 35.4 0.5 2.9e-08 33.8 0.5 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SbcD_C PF12320.8 KIR65084.1 - 0.028 14.7 0.4 1.2 9.4 0.1 2.9 2 1 1 3 3 3 0 Type 5 capsule protein repressor C-terminal domain Collagen PF01391.18 KIR65084.1 - 0.44 10.3 10.0 0.1 12.4 5.4 2.2 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 KIR65085.1 - 2.1e-41 142.0 0.0 2.9e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR65085.1 - 1.7e-22 80.0 0.0 2.2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PsbP PF01789.16 KIR65085.1 - 6.2e-09 36.2 0.1 1.1e-08 35.4 0.1 1.4 1 0 0 1 1 1 1 PsbP APH PF01636.23 KIR65085.1 - 0.0027 17.6 3.1 1.1 9.1 0.7 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIR65085.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIR65085.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MM_CoA_mutase PF01642.22 KIR65086.1 - 7.7e-218 724.2 0.1 8.7e-218 724.0 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Peptidase_M20 PF01546.28 KIR65087.1 - 6.3e-31 107.7 0.1 8.2e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIR65087.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4349 PF14257.6 KIR65088.1 - 5.6e-64 215.5 5.5 7e-64 215.2 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DivIC PF04977.15 KIR65088.1 - 0.44 10.3 1.6 2.9 7.7 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4131 PF13567.6 KIR65088.1 - 0.8 9.3 0.0 0.8 9.3 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Lactamase_B_3 PF13483.6 KIR65089.1 - 1.9e-17 63.6 0.1 2.3e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KIR65089.1 - 6.1e-10 39.0 1.8 1.2e-09 37.9 1.8 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIR65089.1 - 9.4e-05 22.5 9.5 0.00048 20.2 9.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Acetyltransf_1 PF00583.25 KIR65092.1 - 5e-09 36.4 0.0 4.9e-08 33.2 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIR65092.1 - 2.3e-08 34.2 0.1 7.4e-07 29.3 0.0 2.6 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65092.1 - 2.5e-07 31.0 0.0 6.1e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR65092.1 - 0.00053 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65092.1 - 0.0014 18.6 0.0 0.0053 16.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein PanZ PF12568.8 KIR65092.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ AIG2_2 PF13772.6 KIR65093.1 - 4.2e-21 75.1 0.1 5.4e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 KIR65093.1 - 1.2e-10 42.0 0.1 1.5e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Pyr_redox_2 PF07992.14 KIR65094.1 - 6.1e-57 193.1 6.8 7.9e-57 192.7 6.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIR65094.1 - 1.7e-23 83.0 0.2 6.2e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIR65094.1 - 3.5e-22 78.8 4.3 8.5e-16 58.3 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR65094.1 - 2.9e-15 56.3 0.0 2.5e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR65094.1 - 6.1e-11 42.0 5.2 1.2e-06 27.9 0.7 3.4 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 KIR65094.1 - 2.5e-07 29.8 2.6 0.00073 18.4 1.9 2.5 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KIR65094.1 - 5.2e-07 29.1 13.6 0.00081 18.6 4.0 3.5 3 1 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 KIR65094.1 - 5.2e-07 29.0 5.9 7.9e-06 25.2 0.5 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KIR65094.1 - 1.3e-06 27.9 2.3 0.00028 20.3 0.5 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KIR65094.1 - 3.5e-05 23.5 21.3 0.12 12.0 0.2 4.4 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIR65094.1 - 0.00013 21.5 6.1 0.00013 21.5 6.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIR65094.1 - 0.00013 21.2 0.9 0.00025 20.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIR65094.1 - 0.00028 21.1 3.3 0.077 13.2 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIR65094.1 - 0.00083 19.8 2.8 0.15 12.5 0.4 3.0 3 1 0 3 3 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 KIR65094.1 - 0.0019 17.1 0.4 0.0019 17.1 0.4 1.7 2 0 0 2 2 2 1 Tryptophan halogenase XdhC_C PF13478.6 KIR65094.1 - 0.0032 18.0 1.7 1.7 9.2 0.3 2.7 2 1 0 2 2 2 2 XdhC Rossmann domain 3HCDH_N PF02737.18 KIR65094.1 - 0.0064 16.4 4.6 0.065 13.1 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIR65094.1 - 0.017 14.3 5.2 0.36 10.0 0.8 2.7 2 1 1 3 3 3 0 FAD binding domain Thi4 PF01946.17 KIR65094.1 - 0.042 13.1 1.1 0.073 12.3 0.5 1.9 2 0 0 2 2 2 0 Thi4 family DFP PF04127.15 KIR65094.1 - 0.16 11.7 3.3 0.86 9.4 0.1 2.6 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.18 KIR65094.1 - 0.37 11.0 2.4 36 4.7 0.2 3.3 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_9 PF13454.6 KIR65094.1 - 1.2 9.1 11.3 2.4 8.1 0.1 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding ABC_membrane PF00664.23 KIR65095.1 - 5.5e-62 209.9 4.4 6.9e-62 209.6 4.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR65095.1 - 2.3e-30 105.9 0.0 3.9e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR65095.1 - 0.0011 19.4 0.8 0.0039 17.6 0.2 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 KIR65095.1 - 0.0024 17.6 0.3 0.015 15.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR65095.1 - 0.0027 18.0 0.1 0.024 14.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KIR65095.1 - 0.0028 17.1 0.3 0.42 10.0 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIR65095.1 - 0.0045 17.4 0.0 0.039 14.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EI24 PF07264.11 KIR65095.1 - 0.0053 17.0 0.4 0.012 15.8 0.4 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) RsgA_GTPase PF03193.16 KIR65095.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_membrane_2 PF06472.15 KIR65095.1 - 0.007 15.8 0.6 0.014 14.8 0.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_23 PF13476.6 KIR65095.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIR65095.1 - 0.029 13.9 0.0 0.35 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR65095.1 - 0.035 14.3 0.2 0.24 11.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIR65095.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIR65095.1 - 0.067 12.9 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KIR65095.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KIR65095.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KIR65095.1 - 0.1 12.5 0.9 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KIR65095.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KIR65095.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KIR65095.1 - 0.14 11.3 0.0 0.34 10.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DEAD PF00270.29 KIR65095.1 - 0.15 11.8 0.1 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KIR65095.1 - 0.17 11.6 0.1 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIR65095.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KIR65095.1 - 0.2 11.6 0.5 0.64 9.9 0.0 2.1 3 0 0 3 3 3 0 NACHT domain ABC_membrane PF00664.23 KIR65096.1 - 5.4e-41 141.0 9.1 7e-41 140.7 9.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR65096.1 - 2.4e-27 96.1 0.0 3.6e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR65096.1 - 0.0032 17.9 0.2 0.0066 16.9 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIR65096.1 - 0.0032 16.9 0.0 0.11 11.9 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KIR65096.1 - 0.0037 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KIR65096.1 - 0.017 14.9 0.7 0.073 12.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KIR65096.1 - 0.02 14.0 0.0 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyco_hydro2_C5 PF18565.1 KIR65096.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 RsgA_GTPase PF03193.16 KIR65096.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KIR65096.1 - 0.06 13.4 0.3 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 KIR65096.1 - 0.061 13.0 0.9 0.091 12.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIR65096.1 - 0.18 11.4 0.2 0.41 10.2 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KIR65096.1 - 0.28 11.7 0.3 0.41 11.1 0.3 1.1 1 0 0 1 1 1 0 AAA domain MarR PF01047.22 KIR65097.1 - 1.5e-14 53.7 0.0 2.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR65097.1 - 9.5e-10 38.2 0.9 2.9e-09 36.7 0.9 1.9 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR65097.1 - 2.4e-09 37.5 0.2 4.2e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 KIR65097.1 - 0.00061 19.6 0.0 0.00093 19.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB SMC_ScpB PF04079.16 KIR65097.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HxlR PF01638.17 KIR65097.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 1 0 2 2 2 1 HxlR-like helix-turn-helix PadR PF03551.14 KIR65097.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.7 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_IclR PF09339.10 KIR65097.1 - 0.021 14.6 0.2 0.055 13.3 0.1 1.8 1 1 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 KIR65097.1 - 0.022 15.1 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DoxX_2 PF13564.6 KIR65098.1 - 2.9e-05 24.1 16.8 2.9e-05 24.1 16.8 1.9 2 1 0 2 2 2 1 DoxX-like family DoxX PF07681.12 KIR65098.1 - 0.005 17.4 12.5 0.005 17.4 12.5 2.3 3 0 0 3 3 3 1 DoxX TetR_C_33 PF13305.6 KIR65099.1 - 4.3e-18 66.0 6.5 4.3e-18 66.0 6.5 2.1 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65099.1 - 3.2e-11 42.8 0.9 3.2e-11 42.8 0.9 2.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 KIR65099.1 - 0.0012 19.0 3.0 0.0012 19.0 3.0 2.1 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal LacI PF00356.21 KIR65099.1 - 0.21 11.4 2.8 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family MarR PF01047.22 KIR65100.1 - 1.8e-09 37.4 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR65100.1 - 1.9e-08 34.1 1.3 1.9e-08 34.1 1.3 2.7 2 1 1 3 3 3 1 MarR family HTH_27 PF13463.6 KIR65100.1 - 5.8e-05 23.5 0.1 0.00036 21.0 0.0 2.2 1 1 1 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 KIR65100.1 - 0.0031 17.4 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 KIR65100.1 - 0.021 15.0 0.0 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain IMPDH PF00478.25 KIR65101.1 - 1e-102 343.7 3.3 1.3e-102 343.4 3.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KIR65101.1 - 6.4e-17 61.7 7.3 8.7e-08 32.5 0.0 4.0 4 1 1 5 5 5 2 CBS domain NMO PF03060.15 KIR65101.1 - 4.9e-05 22.9 5.2 4.9e-05 22.9 5.2 2.4 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 KIR65101.1 - 6.5e-05 22.1 11.6 0.00052 19.2 11.6 2.2 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KIR65101.1 - 7.4e-05 22.3 0.2 0.0046 16.5 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein Aldolase PF01081.19 KIR65101.1 - 0.0026 17.2 2.4 0.0053 16.2 1.1 2.0 2 0 0 2 2 2 1 KDPG and KHG aldolase Glu_synthase PF01645.17 KIR65101.1 - 0.0074 15.5 0.6 0.011 14.8 0.6 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Peptidase_A4 PF01828.17 KIR65101.1 - 0.054 13.0 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase A4 family Methyltransf_24 PF13578.6 KIR65101.1 - 0.16 13.0 1.4 0.75 10.8 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain CPSase_L_D2 PF02786.17 KIR65102.1 - 3.2e-78 262.1 0.0 6.3e-78 261.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIR65102.1 - 4.3e-43 146.3 0.1 8.8e-43 145.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIR65102.1 - 3.2e-37 126.9 0.0 6.9e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIR65102.1 - 2.4e-17 62.5 0.6 1.1e-16 60.5 0.6 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KIR65102.1 - 6.5e-09 35.6 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIR65102.1 - 8.9e-06 25.4 0.0 2.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KIR65102.1 - 0.0002 21.1 0.4 0.001 18.8 0.2 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like LAL_C2 PF18603.1 KIR65102.1 - 0.00021 21.4 1.1 0.0016 18.6 0.1 3.0 3 0 0 3 3 3 1 L-amino acid ligase C-terminal domain 2 HlyD_3 PF13437.6 KIR65102.1 - 0.00037 21.2 0.1 1.9 9.2 0.0 3.4 4 0 0 4 4 4 2 HlyD family secretion protein HlyD_D23 PF16576.5 KIR65102.1 - 0.013 14.8 0.5 2.5 7.3 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_Ter PF15632.6 KIR65102.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 KIR65102.1 - 0.12 12.4 0.8 0.39 10.7 0.3 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 KIR65102.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PadR PF03551.14 KIR65103.1 - 2.6e-11 43.3 0.0 3.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 KIR65103.1 - 6.2e-05 23.6 0.0 0.0001 22.9 0.0 1.4 1 0 0 1 1 1 1 Virulence activator alpha C-term HTH_34 PF13601.6 KIR65103.1 - 0.032 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 KIR65103.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain ABC_tran PF00005.27 KIR65104.1 - 1.7e-29 103.1 0.0 2.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF4162 PF13732.6 KIR65104.1 - 2.7e-11 44.0 0.0 4.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_21 PF13304.6 KIR65104.1 - 1.2e-10 41.7 0.0 6.2e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIR65104.1 - 5.4e-05 23.1 0.0 0.046 13.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SRP54 PF00448.22 KIR65104.1 - 0.00014 21.5 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KIR65104.1 - 0.0048 17.4 0.0 0.0076 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR65104.1 - 0.007 16.8 0.2 0.014 15.8 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIR65104.1 - 0.013 15.2 0.5 0.028 14.2 0.2 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KIR65104.1 - 0.014 15.6 0.0 0.17 12.1 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KIR65104.1 - 0.024 14.9 0.1 0.21 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR65104.1 - 0.032 14.0 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KIR65104.1 - 0.048 14.1 0.1 0.35 11.3 0.1 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 KIR65104.1 - 0.23 10.0 0.0 4.4 5.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 KIR65105.1 - 7.5e-30 103.9 13.0 9e-30 103.7 13.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR65105.1 - 5e-15 55.5 10.8 6.1e-15 55.2 10.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3488 PF11992.8 KIR65105.1 - 8.3 5.3 18.0 13 4.6 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Methyltransf_3 PF01596.17 KIR65106.1 - 2.7e-49 167.2 0.0 3.3e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIR65106.1 - 3.1e-16 60.3 0.0 5.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR65106.1 - 0.00013 22.6 0.0 0.00024 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KIR65106.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KIR65106.1 - 0.028 14.2 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65106.1 - 0.095 13.4 0.0 0.21 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Maf PF02545.14 KIR65107.1 - 5.8e-50 169.4 0.0 6.6e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MAF_flag10 PF01973.18 KIR65107.1 - 0.25 11.0 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 TFCD_C PF12612.8 KIR65108.1 - 0.0074 16.1 0.0 0.0085 15.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal MutL PF13941.6 KIR65108.1 - 0.011 14.4 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 0 MutL protein T2SSF PF00482.23 KIR65108.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ACC_epsilon PF13822.6 KIR65109.1 - 6.8e-14 52.3 12.6 7.9e-14 52.1 12.6 1.0 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.25 KIR65110.1 - 1.5e-44 152.4 0.0 2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR65110.1 - 1.4e-26 93.3 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIR65110.1 - 0.0002 21.4 1.3 0.00096 19.1 0.2 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIR65110.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIR65110.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIR65110.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FxsA PF04186.13 KIR65111.1 - 0.0055 16.8 2.1 0.0065 16.6 2.1 1.0 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein SLATT_1 PF18181.1 KIR65111.1 - 0.02 14.8 0.4 0.024 14.5 0.4 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4131 PF13567.6 KIR65111.1 - 0.044 13.4 2.6 0.054 13.1 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Glyco_hydro_25 PF01183.20 KIR65112.1 - 5.9e-51 173.2 1.6 7.3e-51 172.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Peptidase_M50B PF13398.6 KIR65113.1 - 7.4e-64 215.1 15.3 9.2e-64 214.8 15.3 1.0 1 0 0 1 1 1 1 Peptidase M50B-like DUF3267 PF11667.8 KIR65113.1 - 0.084 13.2 0.4 0.084 13.2 0.4 2.6 2 1 1 3 3 3 0 Putative zincin peptidase Sigma70_r4_2 PF08281.12 KIR65114.1 - 1.3e-14 53.6 0.2 1.3e-14 53.6 0.2 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR65114.1 - 7.7e-11 41.6 3.5 1.1e-10 41.1 2.9 1.6 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR65114.1 - 7.4e-08 31.8 0.2 7.4e-08 31.8 0.2 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Phage_antitermQ PF06530.12 KIR65114.1 - 6.7e-05 22.8 0.0 9.2e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 Phage antitermination protein Q Sigma70_ECF PF07638.11 KIR65114.1 - 0.023 14.6 0.2 0.033 14.1 0.2 1.3 1 1 0 1 1 1 0 ECF sigma factor FANCF PF11107.8 KIR65114.1 - 0.033 13.4 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) DUF3106 PF11304.8 KIR65114.1 - 0.034 14.6 0.2 0.5 10.9 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) TPR_12 PF13424.6 KIR65114.1 - 0.17 12.2 2.6 0.26 11.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIR65114.1 - 0.17 12.1 0.4 0.17 12.1 0.4 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIR65114.1 - 0.39 11.5 0.2 0.39 11.5 0.2 4.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Carboxyl_trans PF01039.22 KIR65116.1 - 2.2e-203 676.4 0.1 2.5e-203 676.2 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KIR65116.1 - 0.034 13.6 0.2 0.034 13.6 0.2 1.7 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) BPL_C PF02237.17 KIR65117.1 - 6.7e-12 45.1 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB PF03099.19 KIR65117.1 - 4.1e-11 42.9 0.0 7.7e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB_2 PF16917.5 KIR65117.1 - 5.7e-10 39.0 0.4 2.8e-09 36.8 0.1 1.9 1 1 1 2 2 2 1 Biotin/lipoate A/B protein ligase family Head-tail_con PF12236.8 KIR65117.1 - 0.11 11.0 0.5 0.52 8.7 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage head to tail connecting protein Flag1_repress PF03614.13 KIR65117.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin bPH_2 PF03703.14 KIR65118.1 - 4.6e-19 68.4 0.1 6.5e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain GtrA PF04138.14 KIR65119.1 - 8.9e-22 77.5 9.7 1.2e-21 77.1 9.7 1.2 1 0 0 1 1 1 1 GtrA-like protein PEPCK_GTP PF00821.18 KIR65120.1 - 4.6e-171 568.5 0.0 5.8e-171 568.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KIR65120.1 - 1.1e-103 345.5 0.0 1.4e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Stealth_CR1 PF17101.5 KIR65120.1 - 0.017 14.8 0.7 0.017 14.8 0.7 2.1 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 Prenyltransf PF01255.19 KIR65121.1 - 1.1e-70 237.6 0.0 1.4e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Trehalose_PPase PF02358.16 KIR65122.1 - 4.6e-27 94.7 0.0 6.8e-27 94.1 0.0 1.3 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 KIR65122.1 - 0.16 11.6 0.0 0.74 9.5 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR65122.1 - 0.25 11.7 8.8 1.7 9.0 1.3 3.4 1 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 KIR65123.1 - 0.36 11.3 1.7 0.62 10.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) HTH_3 PF01381.22 KIR65124.1 - 5.1e-08 32.8 0.0 8.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR65124.1 - 2.1e-06 28.0 1.7 2.1e-06 28.0 1.7 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR65124.1 - 6.7e-06 26.0 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1323 PF07037.11 KIR65124.1 - 0.00013 22.4 0.1 0.00036 20.9 0.2 1.6 2 0 0 2 2 2 1 Putative transcription regulator (DUF1323) HTH_23 PF13384.6 KIR65124.1 - 0.00013 21.6 0.6 0.00029 20.6 0.6 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_26 PF13443.6 KIR65124.1 - 0.00015 22.1 0.0 0.00024 21.5 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_29 PF13551.6 KIR65124.1 - 0.0011 18.9 1.0 0.0028 17.7 0.5 1.9 2 0 0 2 2 2 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 KIR65124.1 - 0.0028 18.1 0.6 0.006 17.1 0.6 1.6 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_28 PF13518.6 KIR65124.1 - 0.026 14.6 0.5 0.061 13.5 0.5 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 KIR65124.1 - 0.04 14.1 0.2 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.21 KIR65124.1 - 0.073 12.9 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_11 PF08279.12 KIR65124.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 HTH domain MerR PF00376.23 KIR65124.1 - 0.15 11.8 2.1 0.28 11.0 0.1 2.1 2 0 0 2 2 2 0 MerR family regulatory protein Phage_NinH PF06322.11 KIR65124.1 - 0.25 11.2 1.3 0.76 9.7 0.1 2.2 1 1 1 2 2 2 0 Phage NinH protein PhoH PF02562.16 KIR65126.1 - 1.7e-53 181.2 0.0 2.1e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 KIR65126.1 - 9.8e-28 97.0 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 KIR65126.1 - 1.2e-07 31.6 0.2 2.1e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR65126.1 - 0.021 15.1 0.3 0.073 13.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIR65126.1 - 0.068 12.9 0.1 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KIR65126.1 - 0.11 12.9 0.5 0.27 11.6 0.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain SLT PF01464.20 KIR65127.1 - 9.7e-05 22.0 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Menin PF05053.13 KIR65127.1 - 0.0061 15.0 1.5 0.0069 14.8 1.5 1.0 1 0 0 1 1 1 1 Menin TAF4 PF05236.14 KIR65127.1 - 0.02 14.7 4.3 0.021 14.6 4.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CT47 PF15623.6 KIR65127.1 - 0.18 11.6 9.8 0.25 11.2 9.8 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF2229 PF09989.9 KIR65127.1 - 3.2 7.4 6.6 4.4 6.9 6.6 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1068 PF06364.12 KIR65127.1 - 5 7.0 10.2 7.1 6.5 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Rhomboid PF01694.22 KIR65128.1 - 1.9e-23 83.1 10.7 3e-23 82.5 10.7 1.3 1 0 0 1 1 1 1 Rhomboid family DUF543 PF04418.12 KIR65128.1 - 3.3 7.8 7.9 5.4 7.1 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Pyr_redox_2 PF07992.14 KIR65129.1 - 1.6e-29 103.1 0.4 2.1e-29 102.7 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR65129.1 - 2.6e-17 63.0 0.0 7.3e-14 51.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR65129.1 - 1.2e-14 54.6 1.1 3.3e-11 43.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR65129.1 - 4.7e-09 35.8 6.8 1.4e-05 24.4 0.9 3.7 3 1 1 4 4 4 3 FAD binding domain HI0933_like PF03486.14 KIR65129.1 - 3.2e-08 32.7 0.1 6e-06 25.2 0.5 3.2 4 0 0 4 4 4 1 HI0933-like protein FAD_oxidored PF12831.7 KIR65129.1 - 9.7e-08 31.8 1.0 1e-05 25.1 1.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR65129.1 - 3.8e-07 30.2 3.6 1.9e-05 24.8 0.2 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR65129.1 - 4.2e-07 29.9 11.3 7e-05 22.6 1.0 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KIR65129.1 - 8.1e-06 25.2 0.5 0.00016 21.0 0.1 2.5 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 KIR65129.1 - 0.00012 21.4 1.3 0.0016 17.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KIR65129.1 - 0.0034 17.4 6.1 4.3 7.3 0.9 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIR65129.1 - 0.011 14.8 4.6 0.41 9.6 0.2 3.1 2 2 2 4 4 4 0 Lycopene cyclase protein GIDA PF01134.22 KIR65129.1 - 0.03 13.4 5.0 0.13 11.3 0.4 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KIR65129.1 - 0.056 12.6 0.1 0.69 9.0 0.0 2.4 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KIR65129.1 - 0.099 13.1 0.5 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding XdhC_C PF13478.6 KIR65129.1 - 0.14 12.7 0.9 13 6.3 0.1 2.6 2 1 1 3 3 3 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KIR65129.1 - 0.3 10.3 2.3 0.32 10.2 0.2 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TetR_C_33 PF13305.6 KIR65130.1 - 3.1e-23 82.5 6.3 3.1e-23 82.5 6.3 2.8 2 2 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65130.1 - 7.5e-08 32.0 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_51 PF18558.1 KIR65130.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Epimerase PF01370.21 KIR65131.1 - 3.9e-06 26.5 0.2 1.8e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 KIR65131.1 - 1.8e-05 24.2 0.5 3e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.6 KIR65131.1 - 0.00028 20.8 1.0 0.00053 19.9 1.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIR65131.1 - 0.0009 19.5 0.0 0.0016 18.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KIR65131.1 - 0.0042 16.7 0.9 0.0077 15.9 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KIR65131.1 - 0.0051 16.5 0.2 0.0086 15.7 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KIR65131.1 - 0.0058 16.8 1.1 0.018 15.3 1.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR65131.1 - 0.0067 15.7 0.3 0.0081 15.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR65131.1 - 0.019 15.5 0.3 0.04 14.5 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KIR65131.1 - 0.02 15.4 0.1 0.039 14.5 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 KIR65131.1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIR65131.1 - 0.035 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIR65131.1 - 0.046 14.3 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KIR65131.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KIR65131.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KIR65131.1 - 0.28 10.4 0.3 0.38 10.0 0.3 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR65131.1 - 2 7.4 7.8 2.8 6.9 1.9 2.3 2 1 0 2 2 2 0 FAD binding domain FBPase_glpX PF03320.13 KIR65132.1 - 1.2e-138 461.2 7.6 1.4e-138 461.0 7.6 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF4265 PF14085.6 KIR65132.1 - 0.079 12.9 0.5 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Invasin_D3 PF09134.10 KIR65133.1 - 0.022 15.1 2.0 0.072 13.4 0.2 2.3 2 0 0 2 2 2 0 Invasin, domain 3 Exonuc_VII_S PF02609.16 KIR65135.1 - 3e-18 65.6 0.1 3.4e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit YihI PF04220.12 KIR65135.1 - 0.065 13.0 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Cas_Csy1 PF09611.10 KIR65135.1 - 0.14 11.2 0.1 0.13 11.3 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Exonuc_VII_L PF02601.15 KIR65136.1 - 3.3e-78 263.3 0.5 4.1e-66 223.6 0.5 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 KIR65136.1 - 4.1e-13 49.4 0.0 1.2e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 KIR65136.1 - 3.1e-06 27.1 0.0 8.6e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Peptidase_S66 PF02016.15 KIR65136.1 - 0.0031 17.6 0.0 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 LD-carboxypeptidase N-terminal domain Apolipoprotein PF01442.18 KIR65136.1 - 0.6 9.9 9.3 0.2 11.5 4.6 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LYTB PF02401.18 KIR65137.1 - 2.9e-89 298.8 0.0 3.4e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 LytB protein DUF815 PF05673.13 KIR65137.1 - 0.008 15.4 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) GAD PF02938.14 KIR65137.1 - 0.084 13.1 0.2 0.66 10.3 0.1 2.2 2 0 0 2 2 2 0 GAD domain CoA_binding_2 PF13380.6 KIR65137.1 - 0.34 11.4 2.6 7.7 7.0 0.2 3.3 2 2 1 3 3 3 0 CoA binding domain LPAM_2 PF13627.6 KIR65138.1 - 1.5 8.8 6.5 3.6 7.6 6.5 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Peptidase_S8 PF00082.22 KIR65139.1 - 2.3e-56 191.2 5.8 2.3e-56 191.2 5.8 1.8 2 0 0 2 2 2 1 Subtilase family PPC PF04151.15 KIR65139.1 - 3.9e-05 24.7 7.9 6.5e-05 24.0 0.2 4.2 4 0 0 4 4 4 1 Bacterial pre-peptidase C-terminal domain DUF2076 PF09849.9 KIR65140.1 - 0.019 15.0 6.2 0.025 14.6 6.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SKG6 PF08693.10 KIR65140.1 - 0.09 12.2 2.5 0.17 11.3 2.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PEPcase PF00311.17 KIR65141.1 - 2.8e-285 948.5 0.0 3.2e-285 948.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Phage_TAC_6 PF09550.10 KIR65141.1 - 0.015 15.7 0.0 0.093 13.2 0.0 2.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC ABC2_membrane_3 PF12698.7 KIR65142.1 - 0.042 13.0 5.0 1.1 8.3 0.0 2.7 2 1 1 3 3 3 0 ABC-2 family transporter protein Peptidase_S66 PF02016.15 KIR65143.1 - 3.1e-24 85.4 0.0 6.6e-24 84.3 0.0 1.5 2 0 0 2 2 2 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 KIR65143.1 - 3.4e-20 72.8 0.0 5.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain PIG-L PF02585.17 KIR65143.1 - 0.033 14.8 0.1 4.8 7.8 0.0 2.4 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase GntR PF00392.21 KIR65144.1 - 1.7e-16 59.6 0.0 1.9e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KIR65144.1 - 6.3e-05 22.8 0.0 9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 KIR65144.1 - 9.8e-05 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 HTH domain PaaX PF07848.12 KIR65144.1 - 0.00025 21.2 0.0 0.00031 20.9 0.0 1.2 1 0 0 1 1 1 1 PaaX-like protein HTH_41 PF14502.6 KIR65144.1 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HrcA_DNA-bdg PF03444.15 KIR65144.1 - 0.026 14.1 0.0 0.028 14.1 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Rrf2 PF02082.20 KIR65144.1 - 0.029 14.7 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator Cob_adeno_trans PF01923.18 KIR65144.1 - 0.22 11.6 0.0 0.27 11.3 0.0 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF505 PF04458.12 KIR65144.1 - 0.3 9.4 0.0 0.33 9.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) CarD_CdnL_TRCF PF02559.16 KIR65146.1 - 3.9e-32 110.8 0.1 1.1e-31 109.3 0.1 1.9 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 KIR65146.1 - 1e-23 83.5 0.0 2.8e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 TRCF domain UvrB_inter PF17757.1 KIR65146.1 - 3.2e-21 75.3 0.0 6.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 KIR65146.1 - 2e-18 66.8 0.4 2.4e-17 63.2 0.5 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR65146.1 - 2.3e-17 63.3 0.4 4.9e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR65146.1 - 2.1e-06 27.9 0.0 3.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIR65146.1 - 0.0042 17.4 0.2 0.017 15.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 KIR65146.1 - 0.0043 15.8 0.0 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UB2H PF14814.6 KIR65146.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 Bifunctional transglycosylase second domain IstB_IS21 PF01695.17 KIR65146.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KIR65146.1 - 0.21 10.8 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SurA_N_3 PF13624.6 KIR65147.1 - 0.00026 20.8 0.8 0.00051 19.9 0.2 1.7 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 KIR65147.1 - 0.0028 17.5 0.2 0.0092 15.9 0.1 1.8 2 0 0 2 2 2 1 SurA N-terminal domain SmpA_OmlA PF04355.13 KIR65147.1 - 0.15 11.9 0.1 0.86 9.4 0.0 2.1 2 0 0 2 2 2 0 SmpA / OmlA family MazG PF03819.17 KIR65148.1 - 3.4e-23 81.6 0.0 7.9e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain TetR_C_25 PF17933.1 KIR65148.1 - 0.19 12.1 1.1 0.56 10.5 0.5 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF885 PF05960.11 KIR65149.1 - 3.5e-102 343.7 4.6 4e-102 343.6 4.6 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) NUDIX PF00293.28 KIR65150.1 - 2.3e-18 66.5 0.1 4.8e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 KIR65150.1 - 1.1e-05 25.0 2.9 1.7e-05 24.3 2.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 KIR65150.1 - 0.00071 20.2 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain DZR PF12773.7 KIR65150.1 - 0.07 13.2 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon Enolase_C PF00113.22 KIR65151.1 - 7.6e-131 435.7 0.0 1e-130 435.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KIR65151.1 - 5.5e-57 191.6 0.3 1.1e-56 190.6 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KIR65151.1 - 1.9e-10 40.7 0.1 2.8e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KIR65151.1 - 1.8e-05 24.0 0.1 3.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Acetyltransf_1 PF00583.25 KIR65152.1 - 5.2e-12 46.0 0.0 7.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR65152.1 - 1.3e-08 35.2 0.1 2.2e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR65152.1 - 7.3e-06 26.1 0.1 7.6e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR65152.1 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65152.1 - 0.0056 16.8 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 KIR65152.1 - 0.046 13.9 1.0 0.094 12.9 1.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ppx-GppA PF02541.16 KIR65153.1 - 4.5e-58 196.9 0.1 5.6e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF2474 PF10617.9 KIR65153.1 - 0.15 12.0 0.5 0.37 10.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) FtsA PF14450.6 KIR65153.1 - 1.3 9.5 4.2 6.4 7.2 1.2 2.8 2 2 0 2 2 2 0 Cell division protein FtsA DUF1996 PF09362.10 KIR65154.1 - 1.5e-24 87.3 0.0 1.8e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) DNA_photolyase PF00875.18 KIR65154.1 - 0.02 14.9 0.1 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 DNA photolyase HR1 PF02185.16 KIR65154.1 - 0.23 11.6 2.6 0.68 10.1 0.2 2.3 2 0 0 2 2 2 0 Hr1 repeat Phage_AlpA PF05930.12 KIR65155.1 - 0.027 14.3 0.3 0.067 13.0 0.3 1.6 1 1 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) PadR PF03551.14 KIR65157.1 - 5.1e-19 68.0 0.2 6.4e-19 67.7 0.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family DUF4872 PF16169.5 KIR65157.1 - 0.03 14.1 0.3 1.2 8.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4872) TrmB PF01978.19 KIR65157.1 - 0.097 12.6 0.1 4.9 7.1 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB SHOCT PF09851.9 KIR65157.1 - 0.27 11.0 1.7 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Short C-terminal domain DLH PF01738.18 KIR65158.1 - 6.1e-46 156.7 0.0 6.8e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIR65158.1 - 0.00013 21.5 0.0 0.0016 17.9 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KIR65158.1 - 0.0019 18.2 0.2 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KIR65158.1 - 0.02 14.5 0.3 0.023 14.3 0.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KIR65158.1 - 0.023 13.4 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UDG PF03167.19 KIR65159.1 - 3.8e-26 91.9 0.0 4.7e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Stealth_CR3 PF17102.5 KIR65159.1 - 0.16 11.9 0.2 0.3 11.0 0.2 1.4 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 Phage_holin_3_6 PF07332.11 KIR65160.1 - 0.0024 17.9 4.0 0.0033 17.4 4.0 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III AAA_3 PF07726.11 KIR65161.1 - 7.7e-64 213.4 0.0 1.5e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIR65161.1 - 1.1e-19 70.0 2.6 2.9e-19 68.7 2.6 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 KIR65161.1 - 4.7e-12 46.1 0.0 9.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KIR65161.1 - 7e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 KIR65161.1 - 0.00017 22.0 0.0 0.00058 20.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIR65161.1 - 0.0013 18.5 0.0 0.026 14.3 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KIR65161.1 - 0.0027 17.5 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIR65161.1 - 0.048 13.0 0.3 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Pyr_redox_2 PF07992.14 KIR65162.1 - 1.7e-39 135.8 0.0 2.1e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR65162.1 - 8.8e-10 39.0 0.0 9.2e-05 22.9 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR65162.1 - 1.4e-07 31.5 0.5 0.018 14.7 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR65162.1 - 2.2e-05 24.5 1.4 0.0024 17.9 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIR65162.1 - 0.00027 21.1 0.3 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIR65162.1 - 0.005 16.0 0.2 2.7 7.0 0.0 3.6 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KIR65162.1 - 0.0052 17.2 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KIR65162.1 - 0.03 13.9 0.1 0.069 12.7 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KIR65162.1 - 0.062 12.6 0.1 0.88 8.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIR65162.1 - 0.077 11.7 0.0 0.54 8.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF1188 PF06690.11 KIR65162.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) SARS_X4 PF08779.10 KIR65163.1 - 0.041 14.1 0.1 2.8 8.2 0.1 2.5 2 0 0 2 2 2 0 SARS coronavirus X4 like BaxI_1 PF12811.7 KIR65164.1 - 1.6e-84 283.1 13.9 1.7e-84 283.0 13.9 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like Bax1-I PF01027.20 KIR65164.1 - 2.6e-08 34.0 26.6 3.2e-08 33.7 26.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 YtpI PF14007.6 KIR65164.1 - 0.018 15.2 6.1 0.018 15.2 6.1 2.2 2 0 0 2 2 2 0 YtpI-like protein HisKA_7TM PF16927.5 KIR65164.1 - 8.7 6.3 22.8 0.83 9.7 18.4 1.5 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase Thiolase_N PF00108.23 KIR65166.1 - 1e-61 208.6 0.0 4.5e-61 206.5 0.0 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR65166.1 - 8.4e-47 157.8 0.4 1.6e-46 157.0 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR65166.1 - 1.9e-05 24.4 1.9 0.00023 20.8 0.3 2.5 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIR65166.1 - 0.036 13.9 0.4 7.9 6.4 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Lipase_GDSL_2 PF13472.6 KIR65167.1 - 9.9e-22 78.2 0.1 3.1e-21 76.6 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR65167.1 - 2.1e-09 37.7 0.0 3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PALP PF00291.25 KIR65168.1 - 8.7e-71 238.7 0.2 2.1e-70 237.5 0.1 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KIR65168.1 - 1.6e-14 54.1 0.2 2.1e-07 31.3 0.1 3.0 2 1 0 2 2 2 2 CBS domain DUF4531 PF15041.6 KIR65169.1 - 0.18 11.9 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) HTH_31 PF13560.6 KIR65171.1 - 4.9e-10 39.6 0.1 3.8e-09 36.7 0.0 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65171.1 - 3.2e-07 30.3 0.0 8.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix Response_reg PF00072.24 KIR65172.1 - 6e-31 106.9 0.1 8.7e-31 106.4 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR65172.1 - 2.3e-15 55.9 0.1 4e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 KIR65172.1 - 0.00023 20.6 0.1 0.00048 19.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIR65172.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Dioxygenase_C PF00775.21 KIR65175.1 - 1.9e-13 50.2 1.2 1.4e-07 31.1 0.0 3.2 2 1 0 2 2 2 2 Dioxygenase Acetyltransf_1 PF00583.25 KIR65176.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR65176.1 - 5.7e-09 36.0 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65176.1 - 1e-08 35.5 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR65176.1 - 7.5e-06 26.0 0.1 4.1e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65176.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIR65176.1 - 0.0001 23.0 0.3 0.00012 22.7 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65176.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1999 PF09390.10 KIR65176.1 - 0.1 12.3 0.0 1.7 8.3 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1999) Lactamase_B_2 PF12706.7 KIR65177.1 - 1.1e-16 61.0 0.9 2.5e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIR65177.1 - 3.1e-11 43.7 4.9 4e-11 43.3 0.8 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KIR65177.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIR65177.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease Peptidase_M42 PF05343.14 KIR65178.1 - 7.8e-55 185.9 0.4 9e-55 185.7 0.4 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KIR65178.1 - 1.1e-08 35.0 0.9 2.4e-08 33.9 0.9 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Iron_transport PF10634.9 KIR65178.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.6 1 1 0 1 1 1 0 Fe2+ transport protein RimK PF08443.11 KIR65179.1 - 7.2e-10 38.8 0.0 7.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIR65179.1 - 1.5e-06 27.9 0.0 5.3e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Acetyltransf_1 PF00583.25 KIR65179.1 - 5.8e-06 26.5 0.0 2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family ATPgrasp_ST PF14397.6 KIR65179.1 - 3.2e-05 23.3 0.0 0.00087 18.6 0.0 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp FR47 PF08445.10 KIR65179.1 - 0.00019 21.3 0.0 0.00043 20.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein ATP-grasp_3 PF02655.14 KIR65179.1 - 0.00043 20.4 0.0 0.003 17.6 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain Acetyltransf_10 PF13673.7 KIR65179.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65179.1 - 0.0024 18.3 0.0 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GSH-S_ATP PF02955.16 KIR65179.1 - 0.0024 17.3 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_YheCD PF14398.6 KIR65179.1 - 0.028 13.7 0.0 0.27 10.4 0.0 2.2 2 1 0 2 2 2 0 YheC/D like ATP-grasp CPSase_L_D2 PF02786.17 KIR65179.1 - 0.028 13.9 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Acetyltransf_6 PF13480.7 KIR65179.1 - 0.035 14.3 4.9 0.17 12.0 0.3 3.3 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain Asn_synthase PF00733.21 KIR65180.1 - 1e-87 295.1 0.0 1.3e-87 294.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KIR65180.1 - 5.2e-40 136.2 0.0 9e-40 135.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIR65180.1 - 6.4e-37 126.7 0.0 1.6e-36 125.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain tRNA_Me_trans PF03054.16 KIR65180.1 - 0.035 12.9 0.1 0.049 12.4 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 KIR65180.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PMSR PF01625.21 KIR65181.1 - 3e-67 225.6 0.1 3.5e-67 225.3 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HIT PF01230.23 KIR65182.1 - 7.1e-17 62.0 0.0 8.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIR65182.1 - 1e-07 32.4 0.0 1.3e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIR65182.1 - 0.19 11.6 0.1 0.84 9.5 0.1 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Cys_Met_Meta_PP PF01053.20 KIR65183.1 - 2.5e-143 477.2 0.0 2.8e-143 477.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIR65183.1 - 1.5e-06 27.6 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIR65183.1 - 2.2e-06 27.2 0.0 3.5e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIR65183.1 - 4.5e-06 25.9 0.0 2.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIR65183.1 - 0.0011 18.4 0.2 0.0015 17.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KIR65183.1 - 0.059 11.9 0.0 0.13 10.8 0.0 1.5 1 1 0 1 1 1 0 Methionine gamma-lyase Amidase PF01425.21 KIR65184.1 - 4.9e-87 292.7 0.6 1.6e-86 291.1 0.6 1.8 1 1 0 1 1 1 1 Amidase DUF4328 PF14219.6 KIR65185.1 - 5.2e-27 94.4 19.0 5.2e-27 94.4 19.0 2.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4328) SSF PF00474.17 KIR65185.1 - 0.018 13.9 0.4 0.52 9.1 0.2 2.1 2 0 0 2 2 2 0 Sodium:solute symporter family DZR PF12773.7 KIR65185.1 - 0.31 11.1 3.6 0.13 12.3 1.1 1.5 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KIR65185.1 - 0.76 9.3 4.4 1.7 8.2 4.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KIR65185.1 - 1.1 9.1 4.4 1.8 8.4 4.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PALP PF00291.25 KIR65186.1 - 7.8e-86 288.1 9.5 1.3e-85 287.4 9.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 KIR65186.1 - 9.5e-06 25.3 0.4 2.6e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 KIR65186.1 - 2.1e-05 25.0 0.0 4.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KIR65186.1 - 2.1e-05 24.4 0.0 5.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain DUF2103 PF09876.9 KIR65186.1 - 0.0065 16.4 0.1 0.048 13.7 0.0 2.3 2 0 0 2 2 2 1 Predicted metal-binding protein (DUF2103) GreA_GreB_N PF03449.15 KIR65187.1 - 5.1e-22 77.8 2.7 6.4e-22 77.5 2.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 KIR65187.1 - 5.5e-18 64.7 0.1 7.8e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF4307 PF14155.6 KIR65188.1 - 1.1e-27 96.0 2.0 1.3e-27 95.8 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) Pox_A14 PF05767.12 KIR65188.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 PIG-L PF02585.17 KIR65189.1 - 8e-27 94.4 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CutA1 PF03091.15 KIR65192.1 - 2.2e-19 69.2 0.0 2.4e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein HTH_31 PF13560.6 KIR65193.1 - 3.9e-12 46.3 3.6 3.9e-12 46.3 3.6 3.6 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65193.1 - 4.5e-06 26.6 0.1 9.2e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR65193.1 - 4.6e-05 23.4 0.0 9.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR65193.1 - 0.0012 18.6 0.2 0.0025 17.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_2 PF07719.17 KIR65193.1 - 0.017 15.2 7.9 2.9 8.2 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIR65193.1 - 0.073 13.6 0.6 0.073 13.6 0.6 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIR65193.1 - 0.08 13.0 1.7 3 8.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIR65193.1 - 6.6 7.6 6.3 2.1e+02 2.9 0.4 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Thioredox_DsbH PF03190.15 KIR65194.1 - 2.7e-70 235.5 0.0 4e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KIR65194.1 - 2e-09 37.5 0.1 4.2e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 KIR65194.1 - 2.4e-06 27.0 5.1 0.025 13.9 0.1 3.3 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 KIR65194.1 - 0.0087 14.6 0.0 0.06 11.8 0.0 2.1 2 1 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KIR65194.1 - 0.062 12.8 0.1 0.32 10.4 0.0 2.0 2 1 0 3 3 3 0 Glycosyl hydrolase family 76 ATP-grasp PF02222.22 KIR65195.1 - 9.1e-47 158.8 0.0 1.3e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KIR65195.1 - 2.7e-17 62.2 0.0 6.1e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KIR65195.1 - 6.1e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 KIR65195.1 - 0.0033 17.2 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PRODH PF18327.1 KIR65195.1 - 0.021 15.0 1.0 0.021 15.0 1.0 2.8 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain LAL_C2 PF18603.1 KIR65195.1 - 0.022 14.9 0.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 TPR_5 PF12688.7 KIR65195.1 - 0.034 14.4 0.1 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 Tetratrico peptide repeat NAD_binding_10 PF13460.6 KIR65195.1 - 0.04 13.8 0.5 0.074 12.9 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Dala_Dala_lig_C PF07478.13 KIR65195.1 - 0.095 12.2 0.0 0.84 9.1 0.0 2.0 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus AIRC PF00731.20 KIR65196.1 - 1.3e-66 222.8 1.2 1.6e-66 222.4 1.2 1.0 1 0 0 1 1 1 1 AIR carboxylase HypA PF01155.19 KIR65197.1 - 0.36 10.9 1.3 0.76 9.8 1.3 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KIR65197.1 - 0.9 9.6 3.8 1.4 9.0 3.8 1.2 1 0 0 1 1 1 0 zinc-ribbons UDPG_MGDP_dh_N PF03721.14 KIR65198.1 - 1.2e-56 191.2 0.0 1.9e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KIR65198.1 - 6.1e-31 106.5 0.0 1.3e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KIR65198.1 - 2.1e-26 92.4 0.0 9.4e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KIR65198.1 - 4.2e-06 27.0 0.0 0.0023 18.1 0.0 2.6 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIR65198.1 - 0.0029 18.1 0.2 7 7.3 0.0 3.6 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIR65198.1 - 0.0062 16.4 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR65198.1 - 0.016 14.6 0.0 0.91 8.9 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiA PF01656.23 KIR65198.1 - 0.2 11.7 0.0 1.4 9.0 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Acyl-CoA_dh_1 PF00441.24 KIR65199.1 - 2.9e-48 163.9 7.6 5.2e-48 163.1 7.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR65199.1 - 1e-29 103.5 0.2 2e-29 102.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIR65199.1 - 2.9e-28 97.9 0.0 5.6e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIR65199.1 - 8e-25 87.7 4.2 8e-25 87.7 4.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PsbX PF06596.11 KIR65200.1 - 1.5 8.9 5.7 0.36 10.8 0.6 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) 4HBT PF03061.22 KIR65201.1 - 6.4e-17 61.7 3.4 1e-16 61.0 3.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KIR65201.1 - 0.097 13.2 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily AMP-binding PF00501.28 KIR65202.1 - 2.5e-49 168.0 0.0 3.2e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIR65202.1 - 1.3e-13 50.6 0.4 3e-13 49.5 0.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIR65202.1 - 1.4e-06 29.1 0.1 4.5e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIR65203.1 - 1.7e-06 26.9 0.8 0.0002 20.1 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Glycos_transf_1 PF00534.20 KIR65204.1 - 6.2e-19 68.2 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR65204.1 - 1.3e-17 64.3 0.8 1.3e-17 64.3 0.8 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIR65204.1 - 7.3e-16 58.8 0.0 2.5e-15 57.1 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR65204.1 - 1e-10 42.3 6.1 1e-10 42.3 6.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIR65204.1 - 5.7e-08 33.1 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_20 PF12840.7 KIR65205.1 - 1.6e-08 34.5 3.3 1.6e-08 34.5 3.3 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR65205.1 - 1.7e-05 24.6 1.6 6.2e-05 22.8 1.6 2.0 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KIR65205.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 KIR65205.1 - 0.0015 18.1 0.0 0.0057 16.2 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 KIR65205.1 - 0.0058 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Fe_dep_repress PF01325.19 KIR65205.1 - 0.0093 16.1 0.0 0.024 14.9 0.0 1.6 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 KIR65205.1 - 0.048 14.0 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator F420_ligase PF01996.16 KIR65206.1 - 3.2e-46 157.7 0.9 3.2e-35 121.6 0.2 2.2 1 1 1 2 2 2 2 F420-0:Gamma-glutamyl ligase UPF0052 PF01933.18 KIR65207.1 - 2.1e-62 211.0 0.0 2.6e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Radical_SAM PF04055.21 KIR65209.1 - 1.1e-27 97.4 0.0 2.9e-14 53.8 0.0 2.7 3 0 0 3 3 3 2 Radical SAM superfamily DUF4331 PF14224.6 KIR65211.1 - 7e-145 483.4 0.0 7.9e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4331) Whib PF02467.16 KIR65213.1 - 2.9e-27 95.1 2.0 3.4e-27 94.8 2.0 1.1 1 0 0 1 1 1 1 Transcription factor WhiB RecO_C PF02565.15 KIR65213.1 - 0.015 15.1 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Recombination protein O C terminal Zincin_1 PF06262.11 KIR65214.1 - 7.5e-13 48.4 0.1 1.3e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Zincin-like metallopeptidase DUF3499 PF12005.8 KIR65215.1 - 2.4e-48 163.8 0.4 2.7e-48 163.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3499) DAO PF01266.24 KIR65216.1 - 1.8e-56 192.3 17.4 2.1e-56 192.0 17.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIR65216.1 - 7.5e-08 31.9 0.4 1.4e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIR65216.1 - 0.00011 21.5 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR65216.1 - 0.00038 20.6 0.3 0.00038 20.6 0.3 2.7 3 1 1 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIR65216.1 - 0.0086 16.6 0.0 0.82 10.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIR65216.1 - 0.02 14.0 0.1 0.085 11.9 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KIR65216.1 - 0.13 11.1 0.6 0.4 9.5 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Aminotran_3 PF00202.21 KIR65217.1 - 4.1e-96 322.1 0.0 5e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FAD_binding_2 PF00890.24 KIR65217.1 - 0.031 13.4 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Beta_elim_lyase PF01212.21 KIR65217.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Fer2_BFD PF04324.15 KIR65217.1 - 0.2 12.0 0.0 0.49 10.8 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain HTH_17 PF12728.7 KIR65218.1 - 0.077 13.2 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_35 PF13693.6 KIR65218.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 KIR65218.1 - 0.67 10.3 7.2 0.3 11.5 3.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR65219.1 - 2.8e-15 55.8 0.5 2.8e-15 55.8 0.5 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KIR65219.1 - 3.1e-12 46.3 0.9 4.9e-12 45.6 0.3 1.5 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 KIR65219.1 - 2.2e-10 39.9 0.4 9.8e-10 37.8 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KIR65219.1 - 7.1e-05 22.7 0.2 0.0002 21.2 0.0 1.8 2 0 0 2 2 2 1 HTH domain HTH_20 PF12840.7 KIR65219.1 - 0.00016 21.6 0.5 0.013 15.6 0.1 2.9 3 1 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR65219.1 - 0.00028 20.4 0.1 0.00067 19.1 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 KIR65219.1 - 0.034 14.0 2.4 0.46 10.4 0.4 2.9 2 2 1 3 3 3 0 MarR family HTH_28 PF13518.6 KIR65219.1 - 0.05 13.7 0.5 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIR65219.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 NapD PF03927.13 KIR65219.1 - 0.079 13.0 0.4 0.43 10.7 0.1 2.2 2 1 0 2 2 2 0 NapD protein HTH_9 PF08221.11 KIR65219.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Lipase_GDSL_2 PF13472.6 KIR65219.1 - 0.096 13.1 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ACT_4 PF13291.6 KIR65219.1 - 0.099 13.2 0.0 0.25 11.9 0.0 1.8 1 1 0 1 1 1 0 ACT domain SBP_bac_8 PF13416.6 KIR65220.1 - 3.9e-28 99.1 0.5 4.9e-28 98.8 0.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR65220.1 - 1.7e-24 86.6 0.2 2.2e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR65220.1 - 6.8e-16 59.1 0.5 9.4e-16 58.6 0.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR65220.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LPAM_2 PF13627.6 KIR65220.1 - 0.033 14.0 5.9 0.09 12.7 5.9 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site TAT_signal PF10518.9 KIR65220.1 - 9.8 6.2 11.0 36 4.4 11.0 2.0 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence BPD_transp_1 PF00528.22 KIR65221.1 - 1.8e-11 44.1 10.9 1.8e-11 44.1 10.9 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component CPP1-like PF11833.8 KIR65221.1 - 0.53 9.9 5.1 0.21 11.2 2.1 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like BPD_transp_1 PF00528.22 KIR65222.1 - 7.3e-18 64.9 16.3 7.3e-18 64.9 16.3 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SNARE_assoc PF09335.11 KIR65222.1 - 4.5 7.8 20.0 5.6e+02 1.0 15.2 3.0 2 1 0 2 2 2 0 SNARE associated Golgi protein DAO PF01266.24 KIR65223.1 - 1.5e-51 176.0 8.1 1.5e-51 176.0 8.1 1.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR65223.1 - 0.00019 20.8 0.4 0.0019 17.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR65223.1 - 0.00023 21.3 1.7 0.00075 19.7 1.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR65223.1 - 0.0033 16.6 9.5 0.012 14.7 8.1 2.4 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KIR65223.1 - 0.03 13.7 1.3 0.058 12.7 1.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR65223.1 - 0.049 12.3 0.3 0.17 10.6 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF5609 PF18429.1 KIR65223.1 - 0.17 11.7 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) Sacchrp_dh_C PF16653.5 KIR65224.1 - 1.4e-23 84.4 0.0 2.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KIR65224.1 - 1.4e-20 73.9 0.1 1.9e-20 73.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KIR65224.1 - 0.039 14.1 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIR65224.1 - 0.057 14.2 0.2 0.096 13.5 0.2 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.21 KIR65224.1 - 0.068 12.5 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 ThiF family GARS_N PF02844.15 KIR65224.1 - 0.089 13.6 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Gp49 PF05973.14 KIR65225.1 - 1.7e-21 76.1 0.0 2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) HTH_37 PF13744.6 KIR65226.1 - 1.8e-11 43.8 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65226.1 - 3.9e-11 42.8 0.1 6.6e-11 42.1 0.1 1.4 1 1 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR65226.1 - 1.2e-10 41.6 1.6 1.7e-10 41.1 0.9 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR65226.1 - 1.3e-07 31.6 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 KIR65226.1 - 1.6e-05 24.3 0.1 3.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_25 PF13413.6 KIR65226.1 - 2.3e-05 24.2 0.2 4.8e-05 23.1 0.2 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR65226.1 - 0.0016 18.2 0.1 0.0037 17.0 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain MqsA_antitoxin PF15731.5 KIR65226.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_Crp_2 PF13545.6 KIR65226.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KIR65226.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 MarR family YdaS_antitoxin PF15943.5 KIR65226.1 - 0.068 13.0 0.3 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 KIR65226.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Pou PF00157.17 KIR65226.1 - 0.088 12.8 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_24 PF13412.6 KIR65226.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PAS PF00989.25 KIR65227.1 - 0.00021 21.3 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold Cuticle_1 PF08140.11 KIR65227.1 - 0.00076 19.5 0.2 2.3 8.3 0.0 2.8 2 0 0 2 2 2 2 Crustacean cuticle protein repeat VBS PF08913.10 KIR65227.1 - 0.002 18.6 0.4 2 8.9 0.1 2.3 2 0 0 2 2 2 2 Vinculin Binding Site PAS_4 PF08448.10 KIR65227.1 - 0.0053 17.0 0.0 3.8 7.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold ChapFlgA PF13144.6 KIR65227.1 - 0.014 15.5 0.2 5.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Chaperone for flagella basal body P-ring formation TonB_C PF03544.14 KIR65227.1 - 0.025 15.0 0.1 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal DUF3483 PF11982.8 KIR65227.1 - 0.046 13.4 0.3 0.069 12.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) Barwin PF00967.17 KIR65227.1 - 0.13 12.1 0.8 7.9 6.4 0.1 2.5 2 1 0 2 2 2 0 Barwin family Tic110 PF16940.5 KIR65227.1 - 4.2 5.7 5.7 9.8 4.5 5.7 1.6 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF4126 PF13548.6 KIR65227.1 - 6.7 6.4 14.3 12 5.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) Aminotran_3 PF00202.21 KIR65228.1 - 3.4e-129 431.1 0.1 3.8e-129 430.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 KIR65229.1 - 2.6e-159 530.6 0.0 2.9e-159 530.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIR65229.1 - 0.012 14.7 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 KIR65230.1 - 8.7e-134 446.5 0.6 1e-133 446.3 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YbaB_DNA_bd PF02575.16 KIR65231.1 - 1.2e-13 51.0 0.0 1.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Occludin_ELL PF07303.13 KIR65231.1 - 0.18 12.6 0.0 0.25 12.1 0.0 1.2 1 0 0 1 1 1 0 Occludin homology domain Flg_hook PF02120.16 KIR65231.1 - 0.33 10.9 3.0 8.9 6.3 0.4 2.3 1 1 1 2 2 2 0 Flagellar hook-length control protein FliK T7SS_ESX_EspC PF10824.8 KIR65232.1 - 0.095 13.2 1.5 1.8 9.1 0.1 2.0 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Gln_amidase PF15644.6 KIR65233.1 - 3.3e-27 95.7 0.9 2.8e-26 92.7 0.0 3.0 3 0 0 3 3 3 1 Papain fold toxin 1, glutamine deamidase RelA_SpoT PF04607.17 KIR65233.1 - 1.3e-05 25.5 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins SseC PF04888.12 KIR65233.1 - 0.019 14.6 16.1 0.034 13.7 16.1 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Big_10 PF17964.1 KIR65235.1 - 2.5e-48 164.5 1.3 4.4e-48 163.7 1.3 1.4 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 KIR65235.1 - 7.1e-16 58.9 1.0 2.9e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 KIR65235.1 - 4.4e-05 24.1 5.6 0.018 15.8 3.8 3.3 3 0 0 3 3 3 1 Bacterial Ig-like domain Big_10 PF17964.1 KIR65236.1 - 4e-46 157.3 0.4 5.8e-46 156.8 0.4 1.3 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 KIR65236.1 - 4.5e-18 66.1 0.1 1e-17 64.9 0.1 1.6 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 KIR65236.1 - 4.1e-05 24.2 2.1 0.00043 20.9 0.5 2.9 2 1 1 3 3 3 1 Bacterial Ig-like domain HTH_18 PF12833.7 KIR65237.1 - 5.6e-26 90.6 1.8 5.6e-26 90.6 1.8 1.9 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR65237.1 - 3.5e-21 74.8 0.0 2e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 KIR65237.1 - 3.4e-20 72.5 0.1 4.5e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family TetR_N PF00440.23 KIR65237.1 - 0.00031 20.5 0.0 0.00095 18.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 KIR65237.1 - 0.0013 18.1 0.7 0.0033 16.8 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 GATase_3 PF07685.14 KIR65237.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain HTH_AsnC-type PF13404.6 KIR65237.1 - 0.048 13.5 0.2 0.22 11.4 0.2 2.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DinB_2 PF12867.7 KIR65237.1 - 0.076 13.5 2.6 0.18 12.3 2.6 1.6 1 0 0 1 1 1 0 DinB superfamily HTH_23 PF13384.6 KIR65237.1 - 0.085 12.7 0.6 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 KIR65237.1 - 0.091 12.8 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KIR65237.1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 KIR65237.1 - 0.32 11.4 4.4 0.11 12.9 0.9 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain RicinB_lectin_2 PF14200.6 KIR65239.1 - 3.7e-32 110.9 31.8 8.3e-15 55.3 4.6 4.8 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR65239.1 - 7.7e-30 103.8 11.8 1.6e-29 102.7 11.8 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF1565 PF07602.11 KIR65239.1 - 0.048 13.0 0.0 0.048 13.0 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1565) BiPBP_C PF06832.12 KIR65239.1 - 0.065 13.3 0.0 0.91 9.6 0.0 2.5 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family ET PF01684.16 KIR65239.1 - 5.3 7.5 5.4 20 5.6 0.1 3.1 1 1 2 3 3 3 0 ET module Flavoprotein PF02441.19 KIR65240.1 - 4.9e-21 75.1 0.1 5.6e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein HTH_38 PF13936.6 KIR65240.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_8 PF13181.6 KIR65241.1 - 5.1e-05 23.2 0.0 0.14 12.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIR65241.1 - 0.00012 22.3 5.4 0.18 12.1 0.3 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat UCR_Fe-S_N PF10399.9 KIR65241.1 - 0.0053 16.1 0.2 0.0053 16.1 0.2 2.8 3 0 0 3 3 3 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal HTH_31 PF13560.6 KIR65241.1 - 0.008 16.5 4.8 0.016 15.6 2.5 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain TAT_signal PF10518.9 KIR65241.1 - 0.017 14.9 0.2 0.017 14.9 0.2 3.1 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence TPR_9 PF13371.6 KIR65241.1 - 0.018 15.1 0.4 0.018 15.1 0.4 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_28 PF13518.6 KIR65241.1 - 0.036 14.2 0.5 0.15 12.2 0.5 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR65241.1 - 0.071 12.9 0.6 0.23 11.3 0.2 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KIR65241.1 - 0.13 12.1 1.4 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TPR_4 PF07721.14 KIR65241.1 - 0.92 10.3 9.1 22 6.1 1.3 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pentapeptide_4 PF13599.6 KIR65243.1 - 6.6e-23 80.7 0.1 3e-08 33.7 0.1 3.2 2 1 2 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KIR65243.1 - 3.8e-16 58.4 0.3 0.00021 20.9 0.0 4.5 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 KIR65243.1 - 2.9e-11 43.3 3.5 0.00012 22.2 0.1 4.4 2 1 2 4 4 4 4 Pentapeptide repeats (9 copies) Beta_helix PF13229.6 KIR65243.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 Right handed beta helix region CHCH PF06747.13 KIR65243.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 CHCH domain Replic_Relax PF13814.6 KIR65244.1 - 3.4e-48 164.3 0.0 4.8e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation Phage_AlpA PF05930.12 KIR65246.1 - 0.0025 17.6 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.7 KIR65246.1 - 0.0049 17.0 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR65246.1 - 0.21 11.4 0.2 0.21 11.4 0.2 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Phage_integrase PF00589.22 KIR65247.1 - 6.9e-17 61.8 0.1 1.5e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 KIR65247.1 - 2.1e-08 34.3 0.0 5.9e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain NACHT PF05729.12 KIR65248.1 - 2.2e-09 37.4 0.5 3.9e-08 33.4 0.5 2.7 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 KIR65248.1 - 2.2e-06 28.0 0.0 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KIR65248.1 - 0.00067 20.1 0.0 0.0078 16.6 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIR65248.1 - 0.0024 18.3 4.7 0.0064 16.9 0.3 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KIR65248.1 - 0.0025 17.6 0.9 0.0046 16.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIR65248.1 - 0.0043 17.4 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KIR65248.1 - 0.0088 15.1 0.1 0.018 14.1 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KIR65248.1 - 0.012 15.6 0.3 0.03 14.2 0.3 1.7 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIR65248.1 - 0.015 15.6 0.1 0.089 13.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR65248.1 - 0.12 12.6 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KIR65248.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rad17 PF03215.15 KIR65248.1 - 0.27 11.1 0.0 0.51 10.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain BMC PF00936.19 KIR65250.1 - 0.027 14.5 0.1 0.084 12.9 0.1 1.8 2 0 0 2 2 2 0 BMC domain Bys1 PF04681.12 KIR65250.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Blastomyces yeast-phase-specific protein TPR_2 PF07719.17 KIR65251.1 - 0.015 15.4 1.6 0.3 11.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIR65251.1 - 8.4 7.3 17.9 2.3 9.1 0.4 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PLDc_2 PF13091.6 KIR65252.1 - 3.9e-05 23.5 0.0 0.00011 22.0 0.0 1.7 2 0 0 2 2 2 1 PLD-like domain Lon_2 PF13337.6 KIR65253.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF429 PF04250.13 KIR65254.1 - 1.9e-36 125.8 14.8 2.2e-36 125.6 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF429) NACHT PF05729.12 KIR65255.1 - 4.7e-07 29.9 0.0 1.3e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KIR65255.1 - 3.9e-05 23.9 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR65255.1 - 0.011 16.1 0.4 0.039 14.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KIR65255.1 - 0.048 13.1 0.0 8.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 KIR65255.1 - 0.068 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 KIR65255.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain NB-ARC PF00931.22 KIR65255.1 - 0.18 10.9 0.0 1.2 8.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Response_reg PF00072.24 KIR65258.1 - 5.9e-24 84.4 0.3 1.1e-23 83.5 0.2 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR65258.1 - 1.6e-20 72.9 0.0 2.6e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal ABC_tran PF00005.27 KIR65259.1 - 5.3e-31 107.9 0.0 6.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65259.1 - 2.8e-05 24.1 0.1 0.03 14.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR65259.1 - 8.8e-05 22.9 1.0 0.00018 22.0 1.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIR65259.1 - 0.00011 21.7 0.0 0.0033 16.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR65259.1 - 0.00042 20.0 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR65259.1 - 0.0064 16.4 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KIR65259.1 - 0.007 16.7 0.2 0.011 16.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 KIR65259.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KIR65259.1 - 0.011 15.4 0.0 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR65259.1 - 0.012 15.7 3.6 0.16 12.1 3.6 2.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR65259.1 - 0.015 15.0 0.4 0.04 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIR65259.1 - 0.094 12.3 1.2 0.38 10.3 1.2 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIR65259.1 - 0.1 11.9 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KIR65259.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 KIR65259.1 - 0.14 11.8 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MacB_PCD PF12704.7 KIR65260.1 - 4.9e-14 53.1 1.9 1.2e-13 51.9 1.9 1.7 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 KIR65260.1 - 4e-11 43.2 0.4 4e-11 43.2 0.4 3.1 3 0 0 3 3 3 1 FtsX-like permease family MerR_1 PF13411.6 KIR65262.1 - 4e-12 46.1 0.0 6.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 KIR65262.1 - 4.8e-06 26.2 0.2 1.2e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 MerR family regulatory protein Glyco_hydro_11 PF00457.17 KIR65263.1 - 1.9e-75 252.4 14.9 1.9e-75 252.4 14.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 RskA PF10099.9 KIR65263.1 - 0.00097 19.5 0.2 2.1 8.6 0.0 2.5 2 1 0 2 2 2 2 Anti-sigma-K factor rskA AdoMet_dc PF02675.15 KIR65264.1 - 1.5e-14 54.1 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Glyco_tran_28_C PF04101.16 KIR65265.1 - 3.6e-05 23.8 0.0 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KIR65265.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 UDPGT PF00201.18 KIR65265.1 - 0.25 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Aldo_ket_red PF00248.21 KIR65266.1 - 3.3e-54 184.1 0.0 3.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_2 PF00535.26 KIR65267.1 - 1.1e-29 103.5 0.1 2.2e-29 102.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR65267.1 - 1.9e-18 67.2 0.2 4e-18 66.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR65267.1 - 2e-07 30.8 0.0 1.8e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIR65267.1 - 4.7e-07 29.9 3.7 1.6e-06 28.2 3.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KIR65267.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 KIR65267.1 - 0.0044 17.4 0.2 0.0069 16.8 0.2 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Chitin_synth_2 PF03142.15 KIR65267.1 - 0.098 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase Aminotran_3 PF00202.21 KIR65268.1 - 1.7e-65 221.3 0.0 2.3e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIR65268.1 - 0.0046 16.2 0.0 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Glycos_transf_2 PF00535.26 KIR65269.1 - 8.1e-31 107.1 0.1 1.1e-30 106.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR65269.1 - 1.7e-17 64.1 0.6 2.6e-17 63.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR65269.1 - 1.8e-08 34.2 0.0 6.8e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIR65269.1 - 2.4e-05 23.9 0.1 5.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KIR65269.1 - 0.0031 18.0 0.0 0.0078 16.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 SSFA2_C PF14723.6 KIR65270.1 - 0.16 11.9 0.1 0.18 11.7 0.1 1.0 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus HisKA_3 PF07730.13 KIR65271.1 - 4.6e-12 46.3 7.8 4.6e-12 46.3 7.8 3.0 4 1 0 4 4 4 1 Histidine kinase HATPase_c_2 PF13581.6 KIR65271.1 - 2.8e-06 27.3 0.6 7.7e-06 25.9 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR65271.1 - 2.8e-06 27.8 0.0 3.9e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIR65272.1 - 1.4e-24 86.4 0.1 2.9e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR65272.1 - 7.1e-19 67.1 0.5 1.2e-18 66.4 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR65272.1 - 0.00012 21.7 0.3 0.00031 20.4 0.3 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR65272.1 - 0.00035 20.0 1.1 0.0039 16.7 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR65272.1 - 0.0015 18.3 2.7 0.046 13.5 0.1 2.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KIR65272.1 - 0.0086 15.6 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 KIR65272.1 - 0.013 16.0 0.1 0.027 14.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 KIR65272.1 - 0.016 15.3 0.1 0.09 12.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 KIR65272.1 - 0.024 14.4 0.3 0.19 11.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 KIR65272.1 - 0.054 13.5 0.2 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.12 KIR65272.1 - 0.17 11.9 2.4 0.33 10.9 0.4 2.2 2 0 0 2 2 2 0 HTH domain AMP-binding PF00501.28 KIR65273.1 - 2.3e-26 92.3 0.0 3.4e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Ricin_B_lectin PF00652.22 KIR65274.1 - 1.2e-30 106.3 8.1 1.9e-30 105.7 6.7 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR65274.1 - 4e-27 94.8 17.7 3.3e-12 47.0 2.4 4.9 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Esterase_phd PF10503.9 KIR65274.1 - 0.0012 18.4 0.2 0.0012 18.4 0.2 2.4 2 1 1 3 3 3 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR65274.1 - 0.0076 15.8 0.3 0.015 14.8 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIR65274.1 - 0.079 12.7 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 KIR65274.1 - 0.36 10.3 2.8 0.41 10.2 0.8 1.8 1 1 1 2 2 2 0 Dienelactone hydrolase family ET PF01684.16 KIR65274.1 - 0.46 10.9 2.5 59 4.1 0.1 3.4 1 1 1 3 3 3 0 ET module RCC1_2 PF13540.6 KIR65275.1 - 5.1e-53 175.9 67.5 2.2e-09 36.9 0.5 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KIR65275.1 - 6e-53 177.3 54.2 7.6e-08 32.9 2.1 8.1 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat FGAR-AT_N PF18076.1 KIR65275.1 - 1 9.4 5.1 2.2 8.3 0.2 3.0 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Reg_prop PF07494.11 KIR65276.1 - 0.011 15.8 1.0 0.49 10.8 0.1 3.5 3 0 0 3 3 3 0 Two component regulator propeller PQQ_3 PF13570.6 KIR65276.1 - 0.29 11.7 16.8 0.79 10.3 0.2 5.9 6 0 0 6 6 6 0 PQQ-like domain DUF72 PF01904.18 KIR65277.1 - 5.5e-52 177.0 1.0 6.8e-52 176.7 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 FtsK_SpoIIIE PF01580.18 KIR65279.1 - 5.2e-118 392.7 0.0 8e-47 159.6 0.0 5.4 6 0 0 6 6 5 5 FtsK/SpoIIIE family AAA_22 PF13401.6 KIR65279.1 - 4.7e-14 52.8 0.0 0.00066 20.0 0.0 4.9 4 1 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KIR65279.1 - 2.8e-11 44.1 6.2 0.026 14.9 0.0 5.2 4 0 0 4 4 4 3 AAA ATPase domain NACHT PF05729.12 KIR65279.1 - 2.1e-10 40.7 0.1 0.0039 17.1 0.1 5.3 4 1 0 4 4 4 2 NACHT domain Peptidase_C14 PF00656.22 KIR65279.1 - 2.1e-09 37.7 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Caspase domain AAA_19 PF13245.6 KIR65279.1 - 1.9e-07 31.6 0.4 0.054 13.8 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KIR65279.1 - 3.2e-06 26.9 1.2 0.04 13.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 KIR65279.1 - 1.2e-05 25.4 0.1 0.68 10.0 0.0 4.1 4 0 0 4 4 4 2 50S ribosome-binding GTPase AAA_30 PF13604.6 KIR65279.1 - 1.8e-05 24.5 2.3 0.013 15.3 0.1 4.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 KIR65279.1 - 0.00013 21.6 0.2 1.7 8.5 0.3 3.8 4 0 0 4 4 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIR65279.1 - 0.00017 22.1 1.3 0.13 12.8 0.1 3.9 4 0 0 4 4 4 1 ABC transporter AAA PF00004.29 KIR65279.1 - 0.00032 21.1 0.3 2.2 8.7 0.1 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIR65279.1 - 0.0015 18.5 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KIR65279.1 - 0.002 18.3 0.5 2.4 8.3 0.0 3.8 4 0 0 4 4 3 1 AAA domain Roc PF08477.13 KIR65279.1 - 0.0048 17.1 0.0 6.5 7.0 0.0 3.7 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KIR65279.1 - 0.009 16.4 0.0 23 5.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase DUF87 PF01935.17 KIR65279.1 - 0.013 15.6 0.4 0.26 11.4 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain Peptidase_C13 PF01650.18 KIR65279.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family AAA_24 PF13479.6 KIR65279.1 - 0.019 14.7 0.0 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 KIR65279.1 - 0.024 14.0 0.0 2.8 7.2 0.0 2.8 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 KIR65279.1 - 0.026 14.1 0.0 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KIR65279.1 - 0.031 14.7 0.2 57 4.1 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 KIR65279.1 - 0.048 13.9 1.8 45 4.3 0.0 4.2 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 KIR65279.1 - 0.061 13.3 1.1 2.2 8.3 0.0 3.0 4 0 0 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIR65279.1 - 0.072 13.6 0.8 70 4.0 0.1 4.1 4 0 0 4 4 4 0 AAA domain DUF853 PF05872.12 KIR65279.1 - 0.083 11.5 2.5 1.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) NB-ARC PF00931.22 KIR65279.1 - 0.086 12.0 0.1 0.41 9.8 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 KIR65279.1 - 0.09 12.7 1.2 7.9 6.4 0.2 2.8 3 0 0 3 3 3 0 NTPase Mg_chelatase PF01078.21 KIR65279.1 - 0.091 12.1 4.6 2.8 7.3 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MobB PF03205.14 KIR65279.1 - 0.1 12.5 1.2 3.3 7.6 0.1 3.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B TniB PF05621.11 KIR65279.1 - 0.14 11.6 0.0 36 3.7 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein PduV-EutP PF10662.9 KIR65279.1 - 0.18 11.6 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KIR65279.1 - 0.19 11.0 0.5 7.1 5.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin TrwB_AAD_bind PF10412.9 KIR65279.1 - 0.2 10.5 0.1 3.9 6.3 0.1 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KIR65279.1 - 1.5 8.4 4.2 2 7.9 0.2 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Clp_N PF02861.20 KIR65280.1 - 2e-26 91.9 3.8 3.2e-12 46.4 0.2 2.6 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component HTH_AsnC-type PF13404.6 KIR65280.1 - 0.065 13.1 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PGM_PMM_I PF02878.16 KIR65282.1 - 4.5e-30 104.2 0.0 7.9e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KIR65282.1 - 4.2e-25 88.3 0.0 1.2e-24 86.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIR65282.1 - 4.2e-24 84.9 0.0 7.9e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KIR65282.1 - 9.1e-16 57.8 0.3 8.2e-15 54.7 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Trm112p PF03966.16 KIR65283.1 - 8.2e-09 35.9 0.5 4.8e-08 33.5 0.5 1.9 1 1 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.12 KIR65283.1 - 0.00081 18.9 0.1 0.0015 18.0 0.1 1.5 1 1 1 2 2 2 1 TFIIB zinc-binding zf-RING_7 PF02591.15 KIR65283.1 - 0.017 15.3 0.9 0.083 13.1 0.8 2.3 2 1 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2_12 PF18658.1 KIR65283.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KIR65283.1 - 0.077 13.1 1.2 0.24 11.5 0.2 2.0 1 1 1 2 2 2 0 Zinc ribbon domain bact-PGI_C PF10432.9 KIR65284.1 - 5.4e-46 156.4 0.0 1.1e-45 155.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 KIR65284.1 - 6e-06 26.1 0.0 0.0014 18.5 0.0 2.5 2 1 0 2 2 2 2 SIS domain SIS_2 PF13580.6 KIR65284.1 - 4.4e-05 23.5 0.5 0.00016 21.7 0.2 2.1 2 0 0 2 2 2 1 SIS domain Cation_efflux PF01545.21 KIR65285.1 - 3e-32 112.0 8.4 3.7e-32 111.7 8.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIR65285.1 - 0.00024 21.2 0.1 0.00036 20.6 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter TctB PF07331.11 KIR65285.1 - 0.23 11.7 12.5 1 9.6 1.4 2.7 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Halogen_Hydrol PF10112.9 KIR65285.1 - 0.61 10.1 2.4 2.4 8.2 0.3 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4131 PF13567.6 KIR65285.1 - 0.85 9.3 5.2 0.16 11.6 0.2 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) PMI_typeI PF01238.21 KIR65286.1 - 3.9e-60 204.0 0.0 2.5e-34 119.1 0.0 2.1 2 0 0 2 2 2 2 Phosphomannose isomerase type I Cupin_2 PF07883.11 KIR65286.1 - 0.083 12.6 0.2 1.8 8.3 0.0 2.8 2 1 1 3 3 3 0 Cupin domain AdoHcyase PF05221.17 KIR65287.1 - 1.4e-151 503.8 0.0 1.5e-151 503.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KIR65287.1 - 6.1e-83 276.7 2.3 8.6e-83 276.2 2.3 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR65287.1 - 2.3e-07 30.3 0.1 4e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KIR65287.1 - 3.1e-06 26.8 0.2 5.1e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KIR65287.1 - 0.00023 21.2 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KIR65287.1 - 0.0037 17.5 0.1 0.0083 16.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 KIR65287.1 - 0.0047 16.3 1.0 0.019 14.3 1.0 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 KIR65287.1 - 0.017 15.7 0.1 0.041 14.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KIR65287.1 - 0.026 15.0 0.1 0.058 13.8 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KIR65287.1 - 0.12 11.6 1.4 0.29 10.4 1.4 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIR65287.1 - 0.15 11.9 0.3 0.43 10.4 0.4 1.7 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FTR1 PF03239.14 KIR65288.1 - 7.2e-52 176.4 14.8 8.9e-52 176.1 14.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF1129 PF06570.11 KIR65288.1 - 2.9 7.3 5.4 0.49 9.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Peptidase_M75 PF09375.10 KIR65289.1 - 2.9e-43 148.4 3.8 3.6e-43 148.1 3.8 1.1 1 0 0 1 1 1 1 Imelysin Cupredoxin_1 PF13473.6 KIR65289.1 - 2.1e-11 43.9 0.0 3.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain HSCB_C PF07743.13 KIR65289.1 - 0.07 13.6 1.1 4.3 7.9 0.1 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4363 PF14276.6 KIR65289.1 - 0.11 12.7 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Dyp_perox PF04261.12 KIR65290.1 - 3.3e-105 351.7 0.0 3.8e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Response_reg PF00072.24 KIR65291.1 - 4.1e-28 97.8 0.0 5.9e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR65291.1 - 1.3e-27 95.7 0.2 3.8e-27 94.2 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 KIR65292.1 - 2.2e-20 73.2 0.0 4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR65292.1 - 5.2e-14 52.0 1.9 7.6e-14 51.5 0.6 2.0 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR65292.1 - 1.4e-10 41.4 1.9 1.4e-10 41.4 1.9 2.2 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 KIR65292.1 - 0.00073 19.5 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4132 PF13569.6 KIR65292.1 - 0.052 13.3 0.2 0.096 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Gmad1 PF10647.9 KIR65293.1 - 1.4e-11 44.6 8.2 1.4e-11 44.6 8.2 1.8 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Pribosyltran PF00156.27 KIR65294.1 - 0.0013 18.2 0.5 0.0024 17.4 0.5 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIR65294.1 - 0.065 12.7 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosom_S30AE_C PF16321.5 KIR65295.1 - 3.8e-22 77.7 0.0 7.2e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 KIR65295.1 - 1.4e-21 77.0 0.7 2.2e-21 76.4 0.7 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein DUF3912 PF13051.6 KIR65295.1 - 0.16 12.2 0.3 0.32 11.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) Acetyltransf_3 PF13302.7 KIR65296.1 - 5.9e-50 169.5 0.0 1.6e-23 83.9 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65296.1 - 1.4e-17 64.0 0.1 1.6e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR65296.1 - 4.3e-10 39.4 0.8 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65296.1 - 3.7e-06 26.8 0.6 0.032 14.2 0.1 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 KIR65297.1 - 5.3e-53 179.4 1.1 1.2e-26 94.1 0.1 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65297.1 - 8.3e-15 55.1 0.1 2.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR65297.1 - 3.5e-10 39.7 4.1 0.00027 20.7 0.6 3.2 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65297.1 - 0.16 12.4 0.0 9.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SecA_DEAD PF07517.14 KIR65298.1 - 4.2e-128 426.7 0.1 6.6e-128 426.0 0.1 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 KIR65298.1 - 1.7e-64 217.6 2.5 3.9e-64 216.4 2.5 1.6 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 KIR65298.1 - 1.7e-34 118.8 0.1 5.4e-34 117.2 0.1 1.9 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 KIR65298.1 - 7.3e-10 38.6 7.6 1.2e-09 37.8 7.6 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 KIR65298.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lge1 PF11488.8 KIR65298.1 - 0.035 14.3 0.8 0.18 12.0 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Helicase_C PF00271.31 KIR65298.1 - 0.062 13.6 1.2 0.44 10.9 0.0 2.5 2 0 0 2 2 2 0 Helicase conserved C-terminal domain HTH_17 PF12728.7 KIR65300.1 - 1.1e-13 51.1 0.1 1.7e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain AbiEi_4 PF13338.6 KIR65300.1 - 0.013 15.6 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_23 PF13384.6 KIR65300.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Tom37 PF10568.9 KIR65300.1 - 0.052 13.9 0.0 0.054 13.8 0.0 1.0 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Phage_AlpA PF05930.12 KIR65300.1 - 0.071 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Myc_target_1 PF15179.6 KIR65302.1 - 0.32 10.9 2.2 0.87 9.5 0.0 2.3 3 0 0 3 3 3 0 Myc target protein 1 Aldedh PF00171.22 KIR65303.1 - 3.6e-96 322.5 0.0 4.2e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PCRF PF03462.18 KIR65304.1 - 5.1e-56 189.6 1.1 6.4e-56 189.3 0.1 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KIR65304.1 - 2.8e-37 127.2 0.1 2.8e-37 127.2 0.1 1.7 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 KIR65304.1 - 0.0019 18.4 1.3 0.0019 18.4 1.3 3.8 4 1 0 4 4 4 1 ABC transporter C-terminal domain ACT_4 PF13291.6 KIR65304.1 - 0.058 14.0 0.1 5.8 7.6 0.0 2.7 3 0 0 3 3 3 0 ACT domain MIR PF02815.19 KIR65304.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 MIR domain ABC_tran PF00005.27 KIR65305.1 - 5.5e-36 124.1 0.0 8.2e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65305.1 - 8.4e-10 38.9 0.4 0.00011 22.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR65305.1 - 4.3e-06 27.2 0.0 9.2e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIR65305.1 - 1.3e-05 24.7 0.0 0.00074 19.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR65305.1 - 2e-05 24.2 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KIR65305.1 - 3.1e-05 23.8 0.0 0.0046 16.7 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIR65305.1 - 5.1e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR65305.1 - 0.00015 22.0 0.0 0.0012 19.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR65305.1 - 0.00021 21.2 0.1 0.0005 20.0 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KIR65305.1 - 0.0019 17.8 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIR65305.1 - 0.0021 18.1 0.0 0.009 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIR65305.1 - 0.0026 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KIR65305.1 - 0.0045 17.4 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KIR65305.1 - 0.0083 15.9 0.0 0.049 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.7 KIR65305.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 KIR65305.1 - 0.011 16.2 0.1 0.04 14.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KIR65305.1 - 0.012 15.2 0.1 0.13 11.9 0.0 2.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KIR65305.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KIR65305.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin PIF1 PF05970.14 KIR65305.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.6 KIR65305.1 - 0.017 15.6 0.0 0.062 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIR65305.1 - 0.022 13.7 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KIR65305.1 - 0.022 13.8 0.2 0.043 12.9 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KIR65305.1 - 0.025 14.7 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KIR65305.1 - 0.032 14.7 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIR65305.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KIR65305.1 - 0.037 14.1 0.1 0.055 13.6 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KIR65305.1 - 0.042 13.6 0.3 0.69 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 KIR65305.1 - 0.044 13.1 0.0 0.095 12.0 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 KIR65305.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.21 KIR65305.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase MobB PF03205.14 KIR65305.1 - 0.15 12.0 0.1 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zot PF05707.12 KIR65305.1 - 0.2 11.2 0.9 2.2 7.9 0.9 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) NB-ARC PF00931.22 KIR65305.1 - 0.25 10.5 0.8 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain FtsX_ECD PF18075.1 KIR65306.1 - 2.6e-25 88.9 2.4 3.7e-25 88.4 2.4 1.2 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 KIR65306.1 - 8.7e-07 29.3 7.2 8.7e-07 29.3 7.2 2.9 3 0 0 3 3 3 1 FtsX-like permease family IncD PF17628.2 KIR65306.1 - 3.3 7.5 8.5 1.1 9.1 1.7 2.6 2 1 1 3 3 3 0 Inclusion membrane protein D SmpB PF01668.18 KIR65307.1 - 3e-61 205.5 0.1 3.5e-61 205.3 0.1 1.0 1 0 0 1 1 1 1 SmpB protein TPP_enzyme_N PF02776.18 KIR65309.1 - 5.3e-43 146.6 0.2 5.3e-43 146.6 0.2 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIR65309.1 - 9.2e-26 90.5 0.0 2.5e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIR65309.1 - 3e-20 72.4 0.0 5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 KIR65309.1 - 0.0019 17.4 0.0 0.0045 16.2 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KIR65309.1 - 0.026 13.5 0.0 0.059 12.3 0.0 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component PNP_UDP_1 PF01048.20 KIR65310.1 - 1.1e-38 132.9 0.3 1.3e-38 132.6 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily TetR_C_6 PF13977.6 KIR65310.1 - 0.028 14.6 0.1 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Aminotran_3 PF00202.21 KIR65311.1 - 4.2e-97 325.4 0.0 5.1e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Met_asp_mut_E PF06368.11 KIR65312.1 - 2.9e-117 391.9 0.0 3.9e-117 391.4 0.0 1.0 1 0 0 1 1 1 1 Methylaspartate mutase E chain (MutE) BTAD PF03704.17 KIR65314.1 - 1.9e-38 132.2 15.5 1.9e-38 132.2 15.5 4.2 4 0 0 4 4 3 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 KIR65314.1 - 3.4e-27 94.5 37.0 4.5e-11 42.9 1.9 5.7 2 1 5 7 7 7 5 Tetratricopeptide repeat NB-ARC PF00931.22 KIR65314.1 - 1e-09 38.0 0.0 3e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain Trans_reg_C PF00486.28 KIR65314.1 - 1e-08 35.1 0.0 3.7e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_7 PF13176.6 KIR65314.1 - 4.5e-08 32.6 7.7 0.13 12.4 0.1 6.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIR65314.1 - 1.8e-07 30.8 24.4 0.16 12.2 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIR65314.1 - 6.6e-06 25.7 8.4 1.4 8.8 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIR65314.1 - 1.5e-05 24.8 0.0 1.7 9.0 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 KIR65314.1 - 0.00029 21.1 0.0 0.00091 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR65314.1 - 0.00041 20.8 0.2 0.00041 20.8 0.2 3.7 4 1 0 4 4 4 1 AAA ATPase domain TPR_MalT PF17874.1 KIR65314.1 - 0.00056 19.4 7.7 0.00056 19.4 7.7 2.9 2 1 1 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 KIR65314.1 - 0.0012 19.3 0.8 0.0012 19.3 0.8 5.8 5 1 1 7 7 6 1 Tetratricopeptide repeat AAA_25 PF13481.6 KIR65314.1 - 0.013 15.0 0.0 0.071 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_10 PF13374.6 KIR65314.1 - 0.014 15.2 38.8 0.041 13.7 0.4 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIR65314.1 - 0.015 15.6 2.3 2.5 8.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 KIR65314.1 - 0.069 12.6 0.1 0.9 8.9 0.0 2.7 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP CbiA PF01656.23 KIR65314.1 - 0.09 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_6 PF13174.6 KIR65314.1 - 0.29 11.9 20.5 16 6.4 0.3 8.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIR65314.1 - 0.93 10.5 55.0 0.082 13.8 0.7 10.4 6 4 4 10 10 9 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KIR65314.1 - 6.9 6.5 9.2 1.9 8.4 0.2 3.4 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal EamA PF00892.20 KIR65315.1 - 3.9e-30 104.8 28.1 9.5e-16 58.2 10.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KIR65315.1 - 2.9 7.1 9.2 8 5.7 4.7 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family zf-CGNR PF11706.8 KIR65316.1 - 2.6e-18 65.6 9.9 4e-18 65.0 9.9 1.3 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 KIR65316.1 - 5.5e-14 52.9 16.9 9.5e-14 52.2 16.9 1.3 1 0 0 1 1 1 1 Putative stress-induced transcription regulator DUF826 PF05696.11 KIR65316.1 - 2.2 8.5 3.6 0.67 10.1 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF826) DDE_Tnp_4 PF13359.6 KIR65317.1 - 3.3e-31 108.1 0.0 4.6e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR65317.1 - 1e-12 47.6 0.0 3.3e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR65317.1 - 2.9e-11 43.4 1.2 2.9e-11 43.4 1.2 2.1 2 1 0 2 2 2 1 Transposase DDE domain CobU PF02283.16 KIR65317.1 - 0.058 13.0 0.2 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase HTH_31 PF13560.6 KIR65318.1 - 8.1e-12 45.3 0.5 8.1e-12 45.3 0.5 4.8 5 2 0 5 5 5 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR65318.1 - 0.00019 21.4 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65318.1 - 0.00035 20.6 0.0 0.00094 19.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix TPR_8 PF13181.6 KIR65318.1 - 0.16 12.3 0.1 73 4.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-NADH-PPase PF09297.11 KIR65319.1 - 0.042 13.5 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain HTH_31 PF13560.6 KIR65320.1 - 1.8e-14 53.8 0.3 1.8e-14 53.8 0.3 3.1 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65320.1 - 1.2e-09 38.1 0.4 4.1e-09 36.4 0.1 2.2 3 0 0 3 3 3 1 Helix-turn-helix HTH_19 PF12844.7 KIR65320.1 - 7.3e-06 25.9 0.1 1.8e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR65320.1 - 0.00047 20.0 0.3 0.0027 17.6 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR65320.1 - 0.00098 18.9 0.0 0.0061 16.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR65320.1 - 0.14 12.6 0.1 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF397 PF04149.12 KIR65321.1 - 2.9e-19 68.9 0.4 3.4e-19 68.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Helicase_C PF00271.31 KIR65322.1 - 7.6e-20 71.3 0.0 1.8e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3883 PF13020.6 KIR65322.1 - 5.9e-13 48.7 0.0 1.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) SNF2_N PF00176.23 KIR65322.1 - 3.6e-11 42.4 0.0 1e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KIR65322.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIR65322.1 - 5.1e-07 29.6 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KIR65322.1 - 0.0094 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 KIR65322.1 - 0.047 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) OmpH PF03938.14 KIR65322.1 - 0.4 11.0 6.6 0.071 13.5 0.9 2.5 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) TetR_C_15 PF17918.1 KIR65323.1 - 0.018 15.8 1.2 0.039 14.7 0.5 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_12 PF13087.6 KIR65324.1 - 5.6e-25 88.1 0.0 8.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIR65324.1 - 1.2e-24 87.5 0.3 8.3e-12 45.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIR65324.1 - 4.1e-12 46.2 9.0 4.6e-07 29.7 0.8 4.3 3 1 1 4 4 4 2 AAA domain Peptidase_C14 PF00656.22 KIR65324.1 - 4.2e-09 36.7 0.0 7.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Caspase domain AAA_19 PF13245.6 KIR65324.1 - 1.3e-06 28.8 0.0 2.5e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KIR65324.1 - 1.5e-06 27.9 1.4 4.3e-06 26.5 0.1 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 KIR65324.1 - 2.7e-05 24.1 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.18 KIR65324.1 - 0.0022 17.8 0.3 1.5 8.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KIR65324.1 - 0.0028 17.1 0.2 0.017 14.6 0.3 2.0 2 0 0 2 2 2 1 PhoH-like protein MTES_1575 PF18741.1 KIR65324.1 - 0.0096 16.1 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 REase_MTES_1575 IstB_IS21 PF01695.17 KIR65324.1 - 0.041 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KIR65324.1 - 0.061 13.5 0.1 0.59 10.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 KIR65324.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RsgA_GTPase PF03193.16 KIR65324.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KIR65324.1 - 0.3 11.4 9.0 6.1 7.2 9.0 3.0 1 1 0 1 1 1 0 AAA ATPase domain Chlorophyllase2 PF12740.7 KIR65325.1 - 0.16 10.9 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF748 PF05359.11 KIR65325.1 - 1.3 9.2 3.8 2.9 8.1 1.6 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF748) AMP-binding PF00501.28 KIR65326.1 - 2.8e-87 293.1 0.2 4.1e-87 292.5 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR65326.1 - 3.6e-53 180.9 0.0 4.7e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KIR65326.1 - 9.7e-26 89.9 0.4 1.6e-12 47.6 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIR65326.1 - 3e-10 40.9 0.3 1.7e-09 38.5 0.3 2.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Prot_ATP_ID_OB PF16450.5 KIR65326.1 - 0.052 13.5 0.3 4.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain p450 PF00067.22 KIR65327.1 - 1.4e-22 80.1 0.0 5.3e-16 58.4 0.0 3.1 2 1 0 3 3 3 3 Cytochrome P450 Condensation PF00668.20 KIR65328.1 - 1e-13 50.8 0.0 1.5e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain DUF3085 PF11284.8 KIR65328.1 - 0.04 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Pribosyltran PF00156.27 KIR65329.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DNA_processg_A PF02481.15 KIR65330.1 - 6.4e-64 215.1 0.2 8.7e-64 214.6 0.2 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A LDcluster4 PF18306.1 KIR65330.1 - 7.7e-06 25.6 6.0 6e-05 22.7 6.0 2.0 1 1 0 1 1 1 1 SLOG cluster4 family YAcAr PF10686.9 KIR65330.1 - 0.85 9.6 6.1 1.8 8.6 2.5 2.8 2 1 1 3 3 3 0 YspA, cpYpsA-related SLOG family DUF397 PF04149.12 KIR65332.1 - 1.9e-20 72.7 1.3 2.1e-20 72.5 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Aldo_ket_red PF00248.21 KIR65333.1 - 2.7e-69 233.6 0.0 3.3e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.24 KIR65333.1 - 0.13 11.7 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Mg_chelatase PF01078.21 KIR65334.1 - 4.8e-07 29.4 0.1 0.014 14.8 0.0 2.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KIR65334.1 - 5.5e-06 26.2 0.0 0.00052 19.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 KIR65334.1 - 7.8e-06 25.9 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIR65334.1 - 0.00088 19.1 0.0 0.0058 16.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 KIR65334.1 - 0.0018 17.3 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 2 PrkA AAA domain Asparaginase_2 PF01112.18 KIR65334.1 - 0.024 13.7 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Asparaginase NACHT PF05729.12 KIR65334.1 - 0.028 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIR65334.1 - 0.031 14.7 0.8 0.081 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KIR65334.1 - 0.054 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KIR65334.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain VWA_2 PF13519.6 KIR65335.1 - 8e-08 32.9 0.0 7.6e-07 29.8 0.0 2.6 1 1 0 1 1 1 1 von Willebrand factor type A domain NifQ PF04891.12 KIR65335.1 - 0.039 14.3 0.6 0.16 12.3 0.6 2.0 1 1 0 1 1 1 0 NifQ VWA PF00092.28 KIR65335.1 - 0.072 13.3 0.0 0.27 11.4 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4226 PF10774.9 KIR65335.1 - 0.32 11.3 8.3 8.9 6.6 0.5 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) TPR_6 PF13174.6 KIR65335.1 - 3.8 8.3 5.1 25 5.8 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat NTP_transf_9 PF04248.12 KIR65337.1 - 2.6e-32 110.6 0.1 2.8e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) FAD_binding_4 PF01565.23 KIR65338.1 - 2.1e-11 43.7 0.2 3.6e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain CMAS PF02353.20 KIR65339.1 - 6.6e-96 320.8 0.0 7.9e-96 320.5 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIR65339.1 - 2.8e-11 43.5 0.0 5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR65339.1 - 1.3e-10 41.9 0.0 2.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65339.1 - 1.6e-10 41.5 0.0 3.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65339.1 - 1e-06 29.4 0.0 2.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65339.1 - 7.6e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR65339.1 - 0.0042 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KIR65339.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 KIR65339.1 - 0.052 13.1 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KIR65339.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AHSA1 PF08327.11 KIR65340.1 - 1.4e-22 80.2 1.3 1.2e-11 44.9 0.0 2.2 2 0 0 2 2 2 2 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KIR65340.1 - 1.8e-14 54.2 8.1 1e-08 35.6 1.3 2.3 2 1 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR65340.1 - 0.084 13.1 1.5 7.8 6.7 0.1 2.9 2 2 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 KIR65340.1 - 0.14 12.3 0.3 1.3 9.1 0.1 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2505) zinc_ribbon_15 PF17032.5 KIR65341.1 - 9.5e-09 35.9 0.2 1.2e-08 35.6 0.2 1.1 1 0 0 1 1 1 1 zinc-ribbon family Zn-ribbon_8 PF09723.10 KIR65341.1 - 0.033 14.3 0.7 9 6.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KIR65341.1 - 0.047 13.4 2.2 5.4 6.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIR65341.1 - 0.12 11.9 2.1 3 7.4 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KIR65341.1 - 0.25 11.3 3.6 3.2 7.8 4.2 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF35_N PF12172.8 KIR65341.1 - 1.2 9.1 5.9 6 6.8 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RhlB PF12300.8 KIR65342.1 - 0.085 13.0 6.8 0.099 12.8 6.8 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB MFS_1 PF07690.16 KIR65343.1 - 1.8e-39 135.7 73.1 6.8e-38 130.5 61.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIR65343.1 - 4.3 5.5 10.1 0.22 9.8 1.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MCD_N PF17408.2 KIR65344.1 - 0.11 12.7 0.3 0.26 11.5 0.3 1.7 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain GntP_permease PF02447.16 KIR65346.1 - 1.5e-130 435.9 48.5 1.7e-74 251.1 11.4 2.0 2 0 0 2 2 2 2 GntP family permease CitMHS PF03600.16 KIR65346.1 - 3.7e-20 72.3 47.6 9.3e-20 71.0 47.6 1.6 1 1 0 1 1 1 1 Citrate transporter FGGY_N PF00370.21 KIR65347.1 - 5.3e-65 219.4 0.0 6.7e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIR65347.1 - 1.3e-35 122.9 0.2 2e-35 122.4 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KIR65347.1 - 0.0026 17.3 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family YidD PF01809.18 KIR65349.1 - 1.5e-19 69.6 0.3 2.5e-19 68.9 0.3 1.3 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor CxC4 PF18717.1 KIR65349.1 - 0.13 12.1 2.1 0.22 11.4 2.1 1.3 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases Trypsin_2 PF13365.6 KIR65350.1 - 0.0008 20.3 1.4 0.0014 19.5 0.5 1.9 1 1 1 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 KIR65350.1 - 0.0054 16.6 0.7 0.011 15.6 0.1 1.7 2 0 0 2 2 2 1 Trypsin AIPR PF10592.9 KIR65351.1 - 2.2e-78 263.9 0.0 2.8e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 AIPR protein Terminase_6C PF17289.2 KIR65351.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Terminase RNaseH-like domain DUF4420 PF14390.6 KIR65352.1 - 4e-77 259.4 0.0 5e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Putative PD-(D/E)XK family member, (DUF4420) Z1 PF10593.9 KIR65353.1 - 1.4e-80 270.1 0.1 4.9e-80 268.3 0.0 1.8 2 0 0 2 2 2 1 Z1 domain HATPase_c_3 PF13589.6 KIR65354.1 - 1.7e-25 89.5 0.0 3.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIR65354.1 - 0.0068 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIR65355.1 - 2.4e-24 85.7 0.0 4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIR65355.1 - 2e-05 25.1 0.0 3.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_3 PF01381.22 KIR65356.1 - 0.011 15.7 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Auto_anti-p27 PF06677.12 KIR65356.1 - 0.52 10.5 2.8 1.1 9.5 2.8 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AP_endonuc_2 PF01261.24 KIR65359.1 - 1.2e-24 86.9 0.7 1.6e-24 86.5 0.7 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 KIR65359.1 - 0.084 12.6 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus RNaseH_pPIWI_RE PF13032.6 KIR65359.1 - 0.38 10.6 4.6 3.5 7.5 0.2 2.6 4 0 0 4 4 4 0 RNaseH domain of pPIWI_RE AAA_30 PF13604.6 KIR65360.1 - 1.1e-08 35.0 1.5 2.1e-08 34.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KIR65360.1 - 3e-07 30.5 0.0 0.0004 20.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KIR65360.1 - 6.6e-06 25.9 0.0 9.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIR65360.1 - 4.4e-05 23.3 0.1 0.53 10.0 0.0 3.2 2 1 1 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KIR65360.1 - 0.00011 22.5 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KIR65360.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 KIR65360.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KIR65360.1 - 0.0097 14.9 0.8 0.014 14.4 0.1 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KIR65360.1 - 0.036 13.7 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KIR65360.1 - 0.27 11.2 0.0 0.43 10.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CBM_3 PF00942.18 KIR65362.1 - 4.2e-07 30.3 0.0 7.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Cellulose binding domain fn3 PF00041.21 KIR65362.1 - 1.6e-06 28.4 0.9 4.6e-06 26.9 0.5 2.1 2 1 0 2 2 2 1 Fibronectin type III domain Acetyltransf_3 PF13302.7 KIR65363.1 - 2.3e-32 112.5 0.1 3e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65363.1 - 3e-11 43.6 0.0 4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR65363.1 - 8.9e-06 25.4 0.7 0.00014 21.6 0.7 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65363.1 - 0.0099 15.8 0.1 0.05 13.6 0.0 2.1 1 1 0 2 2 2 1 FR47-like protein GNAT_acetyltran PF12746.7 KIR65363.1 - 0.027 14.1 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.7 KIR65363.1 - 0.06 13.5 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 KIR65364.1 - 2.5e-45 154.9 0.0 2.7e-43 148.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Endonuclease_1 PF04231.13 KIR65365.1 - 4.3e-40 137.9 0.1 6.2e-40 137.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease I ABC2_membrane_2 PF12679.7 KIR65366.1 - 0.00034 20.0 13.6 0.00034 20.0 13.6 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR65366.1 - 0.0018 18.3 7.3 0.0061 16.5 7.2 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein BTP PF05232.12 KIR65366.1 - 0.035 14.2 1.5 0.035 14.2 1.5 2.7 3 0 0 3 3 3 0 Chlorhexidine efflux transporter UPF0182 PF03699.13 KIR65366.1 - 0.091 10.9 1.7 0.11 10.6 1.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF2062 PF09835.9 KIR65366.1 - 0.36 10.7 11.3 0.06 13.2 6.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2070 PF09843.9 KIR65366.1 - 4.1 5.6 10.5 5.6 5.1 10.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC_tran PF00005.27 KIR65367.1 - 5.9e-24 85.1 0.0 7.8e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65367.1 - 2.7e-10 40.5 0.1 3.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR65367.1 - 0.011 16.3 0.1 0.016 15.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR65367.1 - 0.032 14.0 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR65367.1 - 0.13 12.5 0.0 0.6 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KIR65367.1 - 0.17 11.5 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain HisKA_3 PF07730.13 KIR65368.1 - 4.5e-16 59.1 3.1 4.5e-16 59.1 3.1 2.5 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 KIR65368.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bax1-I PF01027.20 KIR65368.1 - 0.044 13.6 3.1 0.064 13.1 3.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF234 PF03008.14 KIR65369.1 - 3.1e-05 24.4 0.0 3.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Archaea bacterial proteins of unknown function Putative_PNPOx PF01243.20 KIR65372.1 - 2.6e-14 53.2 0.0 3.7e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KIR65372.1 - 1.6e-05 24.5 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like NAD_binding_10 PF13460.6 KIR65373.1 - 8.4e-23 81.2 0.1 9.6e-23 81.0 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR65373.1 - 1.3e-07 31.4 0.5 1.8e-07 31.0 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIR65373.1 - 8.4e-05 22.1 0.2 0.00014 21.5 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4774 PF15999.5 KIR65373.1 - 0.0025 17.6 1.1 0.0066 16.2 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4774) DapB_N PF01113.20 KIR65373.1 - 0.093 12.8 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Beta-lactamase PF00144.24 KIR65374.1 - 4.6e-70 236.5 4.3 5.3e-70 236.3 4.3 1.0 1 0 0 1 1 1 1 Beta-lactamase Pentapeptide PF00805.22 KIR65375.1 - 3e-25 87.4 7.8 1.8e-10 40.3 0.3 4.3 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KIR65375.1 - 2.7e-17 62.7 0.3 5.5e-11 42.5 0.0 3.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KIR65375.1 - 2.1e-12 47.0 12.2 0.0009 19.3 0.0 4.2 3 2 1 4 4 4 3 Pentapeptide repeats (9 copies) DNA_ligase_OB PF03120.16 KIR65375.1 - 0.013 15.4 0.0 0.25 11.3 0.0 2.2 1 1 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain FAP PF07174.11 KIR65376.1 - 0.0063 16.0 11.8 0.0089 15.5 11.8 1.2 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) YjbE PF11106.8 KIR65376.1 - 0.29 11.4 8.3 7.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Fe-S_biosyn PF01521.20 KIR65377.1 - 8.8e-06 25.9 0.0 1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Sulfotransfer_1 PF00685.27 KIR65378.1 - 2.9e-30 105.6 0.0 3.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KIR65378.1 - 7.6e-05 23.2 1.0 0.039 14.3 0.3 3.1 1 1 1 2 2 2 2 Sulfotransferase family Sensor PF13796.6 KIR65378.1 - 0.37 10.8 5.8 0.27 11.2 0.9 2.7 2 0 0 2 2 2 0 Putative sensor Cupin_2 PF07883.11 KIR65379.1 - 2.4e-19 68.8 0.5 3.9e-19 68.1 0.5 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIR65379.1 - 1.5e-07 31.4 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIR65379.1 - 9.5e-07 28.5 0.1 1.2e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KIR65379.1 - 4.3e-05 23.1 0.2 6.8e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ARD PF03079.14 KIR65379.1 - 0.00017 21.8 0.0 0.00026 21.2 0.0 1.4 1 1 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 KIR65379.1 - 0.00064 19.5 0.2 0.00069 19.4 0.2 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 KIR65379.1 - 0.0057 16.5 0.0 0.0077 16.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase JmjC PF02373.22 KIR65379.1 - 0.083 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase Pirin_C PF05726.13 KIR65379.1 - 0.085 13.2 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Pirin C-terminal cupin domain Glyco_hydro_15 PF00723.21 KIR65380.1 - 1.2e-41 143.0 0.0 7.2e-36 123.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 PALP PF00291.25 KIR65381.1 - 7.6e-61 206.1 4.9 8.9e-61 205.9 4.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trm112p PF03966.16 KIR65381.1 - 0.28 11.8 0.8 1.7 9.3 0.1 2.5 3 0 0 3 3 3 0 Trm112p-like protein LigD_N PF13298.6 KIR65382.1 - 1.6e-34 118.3 0.4 2.3e-34 117.8 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) DNA_ligase_A_M PF01068.21 KIR65382.1 - 2.5e-13 50.2 0.0 6.7e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Aldo_ket_red PF00248.21 KIR65383.1 - 1.2e-41 142.8 0.0 3.2e-29 102.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Glyco_hydro_12 PF01670.16 KIR65384.1 - 8.1e-67 225.3 3.1 8.1e-67 225.3 3.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 CBM_2 PF00553.19 KIR65384.1 - 2.7e-33 114.3 11.2 2.7e-33 114.3 11.2 2.8 3 0 0 3 3 3 1 Cellulose binding domain DUF11 PF01345.18 KIR65384.1 - 0.049 13.9 1.0 0.049 13.9 1.0 2.3 2 1 1 3 3 3 0 Domain of unknown function DUF11 CBM49 PF09478.10 KIR65384.1 - 0.2 12.0 3.4 0.2 12.0 1.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 FAD_binding_3 PF01494.19 KIR65385.1 - 2.3e-20 73.1 0.4 3.9e-19 69.1 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR65385.1 - 4.6e-05 22.8 0.2 0.028 13.7 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR65385.1 - 0.00022 20.9 3.5 0.0034 17.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR65385.1 - 0.00043 20.5 0.2 0.001 19.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIR65385.1 - 0.014 14.2 0.1 6.2 5.6 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 KIR65385.1 - 0.016 15.8 0.1 0.036 14.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIR65385.1 - 0.017 14.4 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 KIR65385.1 - 0.045 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 KIR65385.1 - 0.087 11.9 4.6 0.97 8.4 0.2 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIR65385.1 - 0.13 11.5 0.0 0.9 8.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIR65385.1 - 0.14 11.5 0.3 0.26 10.5 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain COX1 PF00115.20 KIR65386.1 - 4e-156 520.2 68.2 4.5e-156 520.0 68.2 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Isochorismatase PF00857.20 KIR65387.1 - 4.5e-36 124.6 0.1 5.3e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Flavi_NS5 PF00972.20 KIR65387.1 - 0.043 12.0 0.0 0.055 11.6 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase NAPRTase_N PF17767.1 KIR65388.1 - 1.9e-27 96.1 0.0 4.1e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain QRPTase_C PF01729.19 KIR65388.1 - 5.7e-06 26.2 0.8 9.2e-06 25.5 0.8 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NAPRTase PF04095.16 KIR65388.1 - 0.00019 21.1 0.1 0.0018 17.9 0.1 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DRTGG PF07085.12 KIR65388.1 - 0.0041 16.9 0.7 0.011 15.5 0.1 1.9 2 0 0 2 2 2 1 DRTGG domain ClpS PF02617.17 KIR65389.1 - 6.5e-22 77.1 0.0 8.3e-22 76.8 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF2017 PF09438.10 KIR65390.1 - 1.7e-39 135.5 0.6 5.2e-35 120.9 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2017) Prok-JAB PF14464.6 KIR65391.1 - 2.4e-28 98.3 1.0 2.9e-28 98.0 1.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KIR65391.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.6 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SpoIIP PF07454.11 KIR65391.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PALP PF00291.25 KIR65392.1 - 8.9e-60 202.6 0.1 1.1e-59 202.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VWA_2 PF13519.6 KIR65392.1 - 0.21 12.3 0.0 31 5.3 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain Lactamase_B_2 PF12706.7 KIR65393.1 - 2.6e-20 72.8 0.0 3.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIR65393.1 - 8.2e-10 39.0 0.1 1.2e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KIR65393.1 - 0.0025 17.7 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glycos_transf_1 PF00534.20 KIR65394.1 - 4.5e-26 91.4 0.0 7.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR65394.1 - 3.8e-24 85.6 1.9 4.5e-24 85.4 0.6 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR65394.1 - 1.7e-21 76.9 10.1 1.7e-21 76.9 10.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIR65394.1 - 1.1e-10 42.2 24.2 1.1e-10 42.2 24.2 3.2 1 1 2 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIR65394.1 - 8.3e-09 35.7 0.0 2.8e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peripla_BP_4 PF13407.6 KIR65394.1 - 0.33 10.5 1.8 5.5 6.5 0.6 2.5 2 1 0 2 2 2 0 Periplasmic binding protein domain YAcAr PF10686.9 KIR65394.1 - 2.1 8.4 7.2 3 7.8 3.2 3.0 2 2 0 2 2 2 0 YspA, cpYpsA-related SLOG family RNase_PH PF01138.21 KIR65395.1 - 4.8e-21 75.6 0.1 1.1e-20 74.4 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIR65395.1 - 4.7e-11 42.5 0.3 7.8e-11 41.8 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ham1p_like PF01725.16 KIR65396.1 - 2.8e-60 203.4 0.0 3.2e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Mem_trans PF03547.18 KIR65397.1 - 3.1e-19 68.7 18.2 1e-11 43.9 3.2 2.0 2 0 0 2 2 2 2 Membrane transport protein Lyase_aromatic PF00221.19 KIR65398.1 - 3.7e-180 599.5 10.1 4.5e-180 599.3 10.1 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Amidohydro_1 PF01979.20 KIR65399.1 - 1.5e-41 142.9 0.5 1.8e-41 142.6 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Peptidase_M20 PF01546.28 KIR65400.1 - 3.1e-22 79.3 0.4 4.5e-22 78.8 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KIR65400.1 - 1.1e-05 25.2 0.6 1.7e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 KIR65400.1 - 0.0015 18.4 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Urocanase_C PF17392.2 KIR65401.1 - 6.2e-93 309.7 0.3 1.7e-92 308.3 0.3 1.7 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 KIR65401.1 - 2.8e-78 262.4 0.0 3.7e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 KIR65401.1 - 8.5e-58 193.6 0.0 1.3e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Urocanase N-terminal domain HTH_6 PF01418.17 KIR65402.1 - 6.6e-12 45.3 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS PF01380.22 KIR65402.1 - 2.6e-07 30.5 0.1 4.8e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 SIS domain HTH_IclR PF09339.10 KIR65402.1 - 0.0071 16.1 3.2 0.039 13.8 0.2 3.3 3 1 0 3 3 3 1 IclR helix-turn-helix domain AstE_AspA PF04952.14 KIR65402.1 - 0.0084 15.2 0.1 0.033 13.3 0.1 2.1 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family MarR_2 PF12802.7 KIR65402.1 - 0.015 15.1 0.4 0.015 15.1 0.4 3.0 3 1 0 3 3 3 0 MarR family HTH_31 PF13560.6 KIR65402.1 - 0.02 15.2 0.8 0.02 15.2 0.8 4.0 3 2 2 5 5 5 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR65402.1 - 0.025 14.6 0.5 0.069 13.1 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_26 PF13443.6 KIR65402.1 - 0.097 13.1 0.1 54 4.3 0.0 3.4 4 0 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.7 KIR65402.1 - 0.099 12.8 0.0 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Polysacc_synt_C PF14667.6 KIR65404.1 - 3.3e-10 40.2 3.5 3.3e-10 40.2 3.5 4.6 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 KIR65404.1 - 0.00024 20.4 6.3 0.00024 20.4 6.3 2.5 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 KIR65404.1 - 0.0024 17.3 12.3 0.0024 17.3 12.3 3.3 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein PS_pyruv_trans PF04230.13 KIR65405.1 - 1.6e-20 74.2 0.0 2.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Csm4_C PF17953.1 KIR65405.1 - 0.2 11.5 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain DUF4253 PF14062.6 KIR65406.1 - 8.2e-37 125.7 0.0 1.3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4253) Response_reg PF00072.24 KIR65407.1 - 1.4e-14 54.2 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR65407.1 - 3.8e-12 45.6 0.0 5.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR65407.1 - 8.5e-07 28.5 0.1 1.7e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR65407.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR65407.1 - 0.0055 16.5 0.3 0.0055 16.5 0.3 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 KIR65407.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KIR65407.1 - 0.099 12.8 1.5 0.23 11.6 0.6 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KIR65407.1 - 1.4 9.0 5.4 0.9 9.6 0.2 2.9 2 1 1 3 3 3 0 Winged helix-turn helix HisKA_3 PF07730.13 KIR65408.1 - 1.1e-11 45.1 8.3 3.5e-11 43.4 2.8 3.1 3 0 0 3 3 3 1 Histidine kinase Sensor PF13796.6 KIR65408.1 - 3.4e-11 43.4 28.8 3.4e-11 43.4 28.8 3.4 3 1 1 4 4 4 1 Putative sensor HATPase_c_2 PF13581.6 KIR65408.1 - 8.9e-06 25.7 0.9 3.1e-05 23.9 0.6 2.1 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR65408.1 - 0.00023 21.7 0.0 0.00055 20.4 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_24 PF13578.6 KIR65409.1 - 3.6e-17 63.3 0.8 6.6e-17 62.5 0.1 1.8 2 1 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 KIR65409.1 - 5.1e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Cephalosporin hydroxylase AbiEi_4 PF13338.6 KIR65409.1 - 0.013 15.6 1.0 0.054 13.7 1.0 2.1 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Pollen_allerg_1 PF01357.21 KIR65410.1 - 3.3e-10 39.9 0.0 5.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.18 KIR65410.1 - 5.6e-10 39.4 0.1 1.5e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Lytic transglycolase Acetyltransf_1 PF00583.25 KIR65411.1 - 2.1e-09 37.6 0.1 2.7e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR65411.1 - 3e-08 33.7 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65411.1 - 1.5e-07 31.7 0.1 2.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65411.1 - 0.00079 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIR65411.1 - 0.034 14.2 0.2 0.083 13.0 0.2 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65411.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Putative_PNPOx PF01243.20 KIR65412.1 - 6e-08 32.8 0.0 9.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KIR65412.1 - 0.00012 22.1 0.5 0.00019 21.5 0.5 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Alpha-amyl_C2 PF07821.12 KIR65412.1 - 0.044 14.0 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Alpha-amylase C-terminal beta-sheet domain AhpC-TSA PF00578.21 KIR65413.1 - 2.9e-37 127.3 0.0 3.4e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR65413.1 - 4e-25 88.2 0.0 4.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KIR65413.1 - 7.6e-05 22.8 0.0 0.00021 21.4 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 KIR65413.1 - 0.0015 18.1 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) CbiM PF01891.16 KIR65414.1 - 5.4e-55 186.4 28.3 6.2e-55 186.2 28.3 1.0 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region ECF_trnsprt PF12822.7 KIR65414.1 - 2.6 8.1 26.5 1.3 9.1 22.8 1.9 2 0 0 2 2 2 0 ECF transporter, substrate-specific component PDGLE PF13190.6 KIR65415.1 - 7.6e-22 77.0 0.1 1.1e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 PDGLE domain DUF4307 PF14155.6 KIR65415.1 - 0.06 13.2 0.0 6.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) CbiQ PF02361.16 KIR65416.1 - 9.1e-30 103.9 6.8 1.1e-29 103.6 6.8 1.1 1 0 0 1 1 1 1 Cobalt transport protein ABC_tran PF00005.27 KIR65417.1 - 4.7e-29 101.6 0.0 5.9e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65417.1 - 9.3e-12 45.4 2.7 5.3e-08 33.0 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR65417.1 - 0.00019 21.0 0.0 0.015 14.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIR65417.1 - 0.00048 19.8 1.3 0.0015 18.2 1.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR65417.1 - 0.002 18.5 0.5 0.0033 17.8 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIR65417.1 - 0.004 16.9 0.1 0.0074 16.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KIR65417.1 - 0.0065 16.6 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KIR65417.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.6 1 1 1 2 2 2 0 NTPase AAA_23 PF13476.6 KIR65417.1 - 0.022 15.2 0.0 0.031 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR65417.1 - 0.024 14.0 0.3 0.046 13.1 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KIR65417.1 - 0.032 13.9 0.7 0.046 13.4 0.7 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR65417.1 - 0.036 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 KIR65417.1 - 0.043 13.6 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIR65417.1 - 0.063 13.0 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIR65417.1 - 0.071 13.4 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 KIR65417.1 - 0.11 11.2 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 KIR65417.1 - 0.12 12.3 0.2 0.41 10.5 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KIR65417.1 - 0.15 12.1 0.2 0.45 10.5 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KIR65417.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thioredoxin_4 PF13462.6 KIR65418.1 - 4e-25 88.9 0.0 5e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KIR65418.1 - 2.2e-11 43.9 0.1 6.7e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain RskA PF10099.9 KIR65418.1 - 0.054 13.8 0.3 0.054 13.8 0.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MauE PF07291.11 KIR65419.1 - 3.3e-11 43.3 6.0 4.2e-11 42.9 6.0 1.3 1 1 0 1 1 1 1 Methylamine utilisation protein MauE DoxX PF07681.12 KIR65419.1 - 5.6e-06 26.9 13.2 1.1e-05 25.9 13.2 1.5 1 0 0 1 1 1 1 DoxX Sigma70_r2 PF04542.14 KIR65420.1 - 2.2e-13 49.7 3.7 5.2e-13 48.6 3.7 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR65420.1 - 1.7e-12 46.8 0.1 3.3e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR65420.1 - 5.8e-05 22.5 0.2 0.00011 21.7 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR65420.1 - 0.00067 19.6 0.4 0.0014 18.6 0.4 1.5 1 1 0 1 1 1 1 ECF sigma factor DUF1775 PF07987.11 KIR65421.1 - 1.8e-51 174.3 3.1 2.3e-51 174.0 3.1 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) DUF4190 PF13828.6 KIR65421.1 - 0.039 13.7 7.0 0.35 10.7 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF2275 PF10039.9 KIR65421.1 - 0.25 11.4 7.0 2.1 8.4 7.0 2.0 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF3040 PF11239.8 KIR65421.1 - 0.39 11.0 7.1 5.9 7.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4605 PF15378.6 KIR65422.1 - 0.13 12.1 4.9 2.4 8.1 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) GT87 PF09594.10 KIR65423.1 - 3.1e-54 184.2 40.9 3.1e-54 184.2 40.9 3.1 4 0 0 4 4 4 2 Glycosyltransferase family 87 Mannosyl_trans PF05007.13 KIR65423.1 - 0.038 13.9 0.1 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Mannosyltransferase (PIG-M) RNase_T PF00929.24 KIR65424.1 - 1.3e-24 87.6 0.0 1.5e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Acetyltransf_1 PF00583.25 KIR65425.1 - 2.1e-06 27.9 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KIR65425.1 - 5.9e-06 27.0 0.0 8.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65425.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 KIR65425.1 - 0.0001 22.0 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_8 PF13523.6 KIR65425.1 - 0.016 14.9 1.0 0.034 13.8 1.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65425.1 - 0.02 15.3 0.1 0.031 14.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 KIR65425.1 - 0.035 13.8 2.8 0.052 13.3 0.8 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_10 PF13673.7 KIR65425.1 - 0.046 13.7 0.1 0.065 13.2 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR65425.1 - 0.13 12.4 4.2 0.064 13.4 1.8 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TetR_C_23 PF17931.1 KIR65426.1 - 9.3e-34 116.3 0.0 1.3e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65426.1 - 7.7e-19 67.2 0.3 2.2e-18 65.7 0.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family RmlD_sub_bind PF04321.17 KIR65426.1 - 0.034 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF393 PF04134.12 KIR65427.1 - 2.5e-10 41.7 0.1 3e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF872 PF05915.12 KIR65428.1 - 0.16 12.1 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Glyco_hydro_3 PF00933.21 KIR65429.1 - 6e-72 242.7 0.4 7.7e-72 242.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ROK PF00480.20 KIR65430.1 - 1.6e-36 126.3 0.0 2.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR65430.1 - 8e-07 28.9 3.0 8e-07 28.9 3.0 3.1 3 1 0 3 3 2 1 MarR family HTH_24 PF13412.6 KIR65430.1 - 2.4e-05 23.8 1.5 2.7e-05 23.6 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIR65430.1 - 6.4e-05 22.8 0.1 0.0002 21.2 0.1 1.8 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 KIR65430.1 - 0.00011 22.1 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KIR65430.1 - 0.0003 20.7 0.6 0.00067 19.6 0.6 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_27 PF13463.6 KIR65430.1 - 0.0026 18.2 0.0 0.0068 16.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KIR65430.1 - 0.0048 16.7 2.8 0.0048 16.7 2.8 3.1 3 0 0 3 3 3 1 IclR helix-turn-helix domain BcrAD_BadFG PF01869.20 KIR65430.1 - 0.0078 15.7 3.2 0.033 13.7 1.7 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Fe_dep_repress PF01325.19 KIR65430.1 - 0.0098 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Crp PF00325.20 KIR65430.1 - 0.014 15.1 0.5 0.031 13.9 0.5 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_AsnC-type PF13404.6 KIR65430.1 - 0.018 14.9 0.7 0.018 14.9 0.7 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 KIR65430.1 - 0.022 14.7 0.1 0.053 13.5 0.1 1.6 1 0 0 1 1 1 0 HTH domain SMC_ScpB PF04079.16 KIR65430.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB HTH_20 PF12840.7 KIR65430.1 - 3.3 7.9 9.9 0.43 10.7 3.5 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain ABC2_membrane_2 PF12679.7 KIR65431.1 - 8.7e-09 35.1 2.9 1.1e-08 34.7 2.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DinB_2 PF12867.7 KIR65431.1 - 0.048 14.2 0.1 0.097 13.2 0.1 1.5 1 0 0 1 1 1 0 DinB superfamily Ac76 PF05814.11 KIR65431.1 - 0.13 12.3 0.1 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) ABC2_membrane_4 PF12730.7 KIR65431.1 - 0.13 12.2 6.4 0.21 11.6 0.3 2.6 3 0 0 3 3 3 0 ABC-2 family transporter protein FtsL PF04999.13 KIR65431.1 - 0.55 10.3 3.9 0.25 11.4 0.2 2.2 2 0 0 2 2 2 0 Cell division protein FtsL DUF4282 PF14110.6 KIR65431.1 - 5.1 7.9 0.0 5.1 7.9 0.0 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) ABC2_membrane_3 PF12698.7 KIR65431.1 - 7.1 5.6 10.5 0.5 9.4 1.6 2.7 2 1 1 3 3 3 0 ABC-2 family transporter protein ABC_tran PF00005.27 KIR65432.1 - 2.9e-26 92.6 0.0 3.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65432.1 - 5.4e-08 33.0 0.9 0.0015 18.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR65432.1 - 0.0069 16.8 0.7 0.019 15.4 0.7 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIR65432.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1633 PF07794.11 KIR65432.1 - 0.028 12.6 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) AAA_23 PF13476.6 KIR65432.1 - 0.029 14.9 0.0 0.044 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR65432.1 - 0.041 13.8 0.0 0.085 12.8 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KIR65432.1 - 0.045 14.0 0.1 1 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIR65432.1 - 0.098 12.9 0.2 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KIR65432.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.8 KIR65432.1 - 0.13 9.7 0.0 0.16 9.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SMC_N PF02463.19 KIR65432.1 - 0.15 11.5 0.0 3.8 6.9 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIR65432.1 - 0.21 12.0 0.0 0.52 10.7 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PfkB PF00294.24 KIR65433.1 - 2.4e-56 191.3 10.2 2.7e-56 191.1 10.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIR65433.1 - 0.0033 16.9 0.4 0.0058 16.0 0.4 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF948 PF06103.11 KIR65434.1 - 0.0098 16.1 0.7 0.11 12.8 0.1 2.6 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) PMC2NT PF08066.12 KIR65434.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Apolipoprotein PF01442.18 KIR65434.1 - 0.44 10.4 5.4 4.5 7.1 0.1 2.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TM140 PF14985.6 KIR65435.1 - 0.017 14.7 0.8 0.023 14.3 0.8 1.3 1 0 0 1 1 1 0 TM140 protein family DUF5353 PF17304.2 KIR65435.1 - 0.11 12.3 0.9 1.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5353) ECH_1 PF00378.20 KIR65436.1 - 3.8e-73 245.9 0.1 4.3e-73 245.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR65436.1 - 2e-32 113.0 0.6 3.2e-31 109.1 0.2 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DIMCO_N PF16844.5 KIR65436.1 - 0.01 16.1 0.3 0.025 14.9 0.3 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Peptidase_S49 PF01343.18 KIR65436.1 - 0.01 15.8 0.1 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 SDH_sah PF01972.16 KIR65436.1 - 0.074 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DNA_binding_1 PF01035.20 KIR65436.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 1 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain TPP_enzyme_N PF02776.18 KIR65437.1 - 2.5e-44 150.9 4.4 3.1e-42 144.1 0.5 3.0 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIR65437.1 - 1.5e-31 109.3 0.0 7.8e-31 106.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIR65437.1 - 3.9e-23 81.7 0.4 1.1e-22 80.3 0.4 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ACP_syn_III PF08545.10 KIR65437.1 - 0.085 12.7 0.4 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HEV_ORF1 PF02444.16 KIR65437.1 - 2.6 8.7 5.7 3.3 8.3 1.2 3.1 3 1 0 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) ABC_tran PF00005.27 KIR65438.1 - 3.7e-27 95.5 0.0 5.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65438.1 - 4.7e-11 43.1 0.0 2.1e-06 27.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KIR65438.1 - 1.8e-06 28.6 0.0 3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) KdpD PF02702.17 KIR65438.1 - 8.7e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_16 PF13191.6 KIR65438.1 - 9e-05 22.9 1.2 9e-05 22.9 1.2 1.8 1 1 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 KIR65438.1 - 0.00095 18.8 0.2 0.0015 18.2 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 KIR65438.1 - 0.0048 17.3 0.0 0.049 14.1 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIR65438.1 - 0.0051 16.6 4.0 0.006 16.3 2.8 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR65438.1 - 0.0083 16.4 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Phosphoprotein PF00922.17 KIR65438.1 - 0.03 13.9 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein AAA_23 PF13476.6 KIR65438.1 - 0.039 14.5 0.0 0.055 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR65438.1 - 0.047 13.4 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BCA_ABC_TP_C PF12399.8 KIR65438.1 - 0.052 13.5 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter cobW PF02492.19 KIR65438.1 - 0.22 11.1 0.3 4.2 6.9 0.1 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KIR65438.1 - 0.28 11.1 0.0 0.41 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 KIR65438.1 - 0.34 10.6 0.0 9.5 5.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane PF01061.24 KIR65439.1 - 1.1e-28 100.1 9.9 1.1e-28 100.1 9.9 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR65439.1 - 4.1e-15 55.7 11.3 7.1e-15 55.0 11.2 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein PLDc_N PF13396.6 KIR65440.1 - 5.6e-12 45.4 4.4 9e-12 44.7 4.4 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal MARVEL PF01284.23 KIR65440.1 - 0.25 11.4 2.6 0.38 10.8 2.6 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF202 PF02656.15 KIR65441.1 - 4.3e-10 39.9 8.4 4.3e-10 39.9 8.4 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF202) LPAM_1 PF08139.12 KIR65441.1 - 0.085 13.4 0.2 0.085 13.4 0.2 3.7 5 1 0 5 5 5 0 Prokaryotic membrane lipoprotein lipid attachment site DUF202 PF02656.15 KIR65442.1 - 5.3e-12 46.0 14.7 1.8e-10 41.1 14.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Acetyltransf_6 PF13480.7 KIR65443.1 - 0.011 15.9 3.0 0.011 15.9 3.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ETF PF01012.21 KIR65445.1 - 5.7e-49 166.5 4.1 6.9e-49 166.2 4.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Usp PF00582.26 KIR65445.1 - 0.025 15.1 0.1 0.84 10.1 0.1 2.5 1 1 0 1 1 1 0 Universal stress protein family DeoRC PF00455.22 KIR65445.1 - 0.084 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 DeoR C terminal sensor domain RskA PF10099.9 KIR65446.1 - 1.4e-25 90.7 15.1 1.9e-25 90.2 15.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DMRT-like PF15791.5 KIR65446.1 - 0.49 10.8 3.6 0.19 12.1 1.1 1.6 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Sigma70_r2 PF04542.14 KIR65447.1 - 5.7e-17 61.3 0.4 1e-16 60.4 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR65447.1 - 7.1e-15 54.4 0.0 1.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR65447.1 - 1.4e-13 50.2 1.5 3.1e-13 49.0 0.0 2.2 2 1 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR65447.1 - 3.4e-08 33.6 0.1 5.4e-08 32.9 0.1 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 KIR65447.1 - 0.0088 15.6 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 KIR65447.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF4397 PF14344.6 KIR65448.1 - 1e-26 94.1 2.4 1.1e-23 84.3 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4397) Sortase PF04203.13 KIR65449.1 - 1.7e-14 53.7 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Sortase domain DAGK_cat PF00781.24 KIR65449.1 - 0.13 11.9 0.7 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Aminotran_5 PF00266.19 KIR65450.1 - 7.9e-64 215.9 0.0 9.3e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIR65450.1 - 7.4e-13 48.4 0.3 1.1e-12 47.8 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase BtpA PF03437.15 KIR65450.1 - 0.0033 16.9 0.8 0.043 13.3 0.5 2.1 2 0 0 2 2 2 1 BtpA family DegT_DnrJ_EryC1 PF01041.17 KIR65450.1 - 0.062 12.6 0.4 0.089 12.1 0.4 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lsr2 PF11774.8 KIR65450.1 - 0.88 9.7 4.1 0.63 10.2 1.7 2.1 2 1 0 2 2 2 0 Lsr2 tRNA_Me_trans PF03054.16 KIR65451.1 - 1.4e-110 369.5 0.0 1.6e-110 369.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KIR65451.1 - 0.0027 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Usp PF00582.26 KIR65451.1 - 0.015 15.8 0.4 0.055 14.0 0.4 2.0 1 1 0 1 1 1 0 Universal stress protein family QueC PF06508.13 KIR65451.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KIR65451.1 - 0.076 12.1 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD synthase Asn_synthase PF00733.21 KIR65451.1 - 0.077 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Meth_synt_2 PF01717.18 KIR65452.1 - 1.6e-13 50.6 0.0 6.9e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Glyoxalase_6 PF18029.1 KIR65453.1 - 2.6e-27 95.7 0.8 2.9e-27 95.5 0.8 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KIR65453.1 - 0.025 14.8 0.0 0.034 14.3 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADP_ribosyl_GH PF03747.14 KIR65454.1 - 1.4e-57 195.7 11.4 1.6e-57 195.5 11.4 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase EAL PF00563.20 KIR65455.1 - 6e-70 235.5 0.0 1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR65455.1 - 7.5e-44 149.3 0.0 1.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Band_7 PF01145.25 KIR65455.1 - 0.014 15.4 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 SPFH domain / Band 7 family Amidase PF01425.21 KIR65456.1 - 6.6e-155 516.5 0.2 8.1e-155 516.2 0.2 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.15 KIR65457.1 - 3.9e-103 344.6 0.0 5.4e-103 344.1 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KIR65457.1 - 4.9e-41 140.1 0.0 6.7e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 GatB domain YqeY PF09424.10 KIR65457.1 - 0.16 12.0 0.2 0.46 10.6 0.2 1.8 1 0 0 1 1 1 0 Yqey-like protein Metallophos PF00149.28 KIR65458.1 - 1.3e-12 48.7 0.0 2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR65458.1 - 1.3e-08 35.2 0.0 4e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4131 PF13567.6 KIR65458.1 - 0.015 15.0 0.5 0.015 15.0 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF998 PF06197.13 KIR65458.1 - 0.13 11.9 8.2 0.19 11.3 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF998) GSDH PF07995.11 KIR65459.1 - 4.9e-68 229.9 0.2 7.2e-68 229.3 0.2 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 KIR65459.1 - 0.0024 17.8 0.0 0.16 12.1 0.0 3.5 4 0 0 4 4 4 1 NHL repeat 2-Hacid_dh_C PF02826.19 KIR65460.1 - 9.5e-48 161.9 0.0 1.2e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIR65460.1 - 0.0048 17.0 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIR65460.1 - 0.014 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh PF00389.30 KIR65460.1 - 0.015 15.0 0.0 0.046 13.4 0.0 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 KIR65460.1 - 0.018 15.5 0.1 0.037 14.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 KIR65460.1 - 0.051 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KIR65460.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KIR65460.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 ThiF family IlvN PF07991.12 KIR65460.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain bPH_6 PF10756.9 KIR65461.1 - 1e-09 38.4 8.7 1e-09 38.4 8.7 1.5 2 0 0 2 2 2 1 Bacterial PH domain Peripla_BP_3 PF13377.6 KIR65462.1 - 1.7e-33 116.3 0.9 2.9e-33 115.6 0.4 1.6 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR65462.1 - 1.3e-16 60.1 0.0 2.6e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 KIR65462.1 - 2.4e-16 60.0 0.0 3.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family MarR_2 PF12802.7 KIR65462.1 - 3e-05 23.8 1.2 0.054 13.4 0.0 3.6 2 2 1 3 3 3 2 MarR family HTH_IclR PF09339.10 KIR65462.1 - 0.0024 17.6 0.4 3.4 7.5 0.0 3.5 3 0 0 3 3 3 1 IclR helix-turn-helix domain TetR_N PF00440.23 KIR65462.1 - 0.0043 16.8 0.8 0.023 14.5 0.1 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Peripla_BP_4 PF13407.6 KIR65462.1 - 0.0048 16.5 0.0 0.0075 15.9 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR65462.1 - 0.0077 16.6 2.4 0.028 14.8 0.4 2.7 2 1 1 3 3 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65462.1 - 0.014 15.5 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.6 KIR65462.1 - 0.025 14.1 0.1 0.75 9.4 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_AraC PF00165.23 KIR65462.1 - 0.029 14.5 0.1 3.9 7.7 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_10 PF04967.12 KIR65462.1 - 0.034 13.9 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 HTH DNA binding domain HTH_AsnC-type PF13404.6 KIR65462.1 - 0.26 11.1 2.3 10 6.0 0.0 3.2 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 KIR65462.1 - 0.34 10.7 1.5 28 4.6 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR65462.1 - 0.66 9.8 2.8 4.9 7.1 0.0 3.1 2 1 1 3 3 3 0 Homeodomain-like domain SBP_bac_1 PF01547.25 KIR65463.1 - 2.4e-27 96.7 10.8 2.4e-27 96.7 10.8 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR65463.1 - 5.5e-27 95.3 9.8 7.1e-27 94.9 9.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR65463.1 - 0.0021 17.5 0.3 0.0061 16.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR65464.1 - 1e-20 74.3 12.4 1e-20 74.3 12.4 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Glyco_hydro_2 PF00703.21 KIR65465.1 - 6.1e-10 39.7 0.0 1.2e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KIR65465.1 - 0.0029 16.8 0.0 0.017 14.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain CBM60 PF16841.5 KIR65465.1 - 0.18 12.2 0.8 2.7 8.5 0.0 2.8 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding Cadherin-like PF12733.7 KIR65465.1 - 2.4 8.8 4.2 7.3 7.2 0.0 3.3 4 0 0 4 4 4 0 Cadherin-like beta sandwich domain Sulfate_transp PF00916.20 KIR65466.1 - 3.9e-68 229.9 23.0 3.9e-68 229.9 23.0 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KIR65466.1 - 3.9e-14 52.3 0.0 8.3e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain HCO3_cotransp PF00955.21 KIR65466.1 - 0.26 10.1 4.8 1.4 7.7 0.2 2.8 3 0 0 3 3 3 0 HCO3- transporter family ILVD_EDD PF00920.21 KIR65469.1 - 7.2e-213 707.9 0.6 8.1e-213 707.7 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family TPP_enzyme_N PF02776.18 KIR65470.1 - 7.8e-56 188.4 1.2 1.9e-55 187.1 0.7 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIR65470.1 - 5.9e-49 165.3 0.1 1.6e-48 163.9 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIR65470.1 - 4.3e-48 163.0 0.4 3.5e-47 160.0 0.3 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KIR65470.1 - 0.011 15.5 0.3 0.02 14.6 0.3 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.16 KIR65470.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit XFP_N PF09364.10 KIR65470.1 - 0.023 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain ALS_ss_C PF10369.9 KIR65471.1 - 8.5e-30 102.8 0.1 3.2e-29 100.9 0.0 1.8 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 KIR65471.1 - 4.5e-19 68.0 0.0 1.1e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 KIR65471.1 - 2.9e-17 62.1 0.1 5.7e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KIR65471.1 - 2.6e-05 24.7 0.2 4.6e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 ACT domain Saccharop_dh_N PF04455.12 KIR65471.1 - 0.036 14.5 0.1 0.21 12.0 0.1 2.0 1 1 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region IlvN PF07991.12 KIR65472.1 - 8e-75 250.0 0.3 1.1e-74 249.6 0.3 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIR65472.1 - 7.7e-66 220.8 0.1 1e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KIR65472.1 - 1.5e-06 28.7 0.1 2.7e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIR65472.1 - 1.9e-06 27.3 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIR65472.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KIR65472.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mur_ligase PF01225.25 KIR65472.1 - 0.055 13.8 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Polysacc_deac_2 PF04748.13 KIR65472.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase 2-Hacid_dh_C PF02826.19 KIR65473.1 - 1.8e-59 200.1 0.0 6e-59 198.4 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIR65473.1 - 5.6e-32 110.2 0.7 9.4e-32 109.5 0.7 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KIR65473.1 - 3.6e-11 42.6 0.4 6.6e-09 35.4 0.1 3.1 3 0 0 3 3 3 1 ACT domain NAD_binding_2 PF03446.15 KIR65473.1 - 0.0092 16.2 1.9 0.035 14.3 0.0 2.8 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 KIR65473.1 - 0.026 15.1 0.0 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 ACT domain ACT_5 PF13710.6 KIR65473.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain AdoHcyase_NAD PF00670.21 KIR65473.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbE PF02424.15 KIR65475.1 - 2.3e-32 112.5 0.1 6.4e-26 91.4 0.8 2.2 1 1 1 2 2 2 2 ApbE family Iso_dh PF00180.20 KIR65476.1 - 3.9e-85 286.1 0.0 4.6e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LPD37 PF18853.1 KIR65476.1 - 0.036 13.6 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 37 Aminotran_4 PF01063.19 KIR65477.1 - 3.4e-34 118.7 0.0 4e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV CMD PF02627.20 KIR65479.1 - 2.6e-14 53.0 2.7 2.6e-14 53.0 2.7 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family AhpC-TSA PF00578.21 KIR65480.1 - 4.5e-33 113.8 0.0 5.4e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIR65480.1 - 3.9e-15 55.8 0.0 4.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 KIR65480.1 - 0.0033 17.3 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC 1-cysPrx_C PF10417.9 KIR65480.1 - 0.027 14.3 0.0 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin HMGL-like PF00682.19 KIR65481.1 - 1.8e-40 139.2 1.5 2.6e-40 138.6 1.5 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIR65481.1 - 6.9e-28 97.2 0.0 1.3e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Candida_ALS_N PF11766.8 KIR65482.1 - 0.092 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding AAA_3 PF07726.11 KIR65483.1 - 9.9e-61 203.4 0.0 2.1e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KIR65483.1 - 5.2e-18 64.6 6.0 1.7e-17 63.0 6.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 KIR65483.1 - 1.3e-13 51.2 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIR65483.1 - 0.0012 19.2 0.0 0.0028 18.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIR65483.1 - 0.0024 17.3 0.7 0.038 13.4 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KIR65483.1 - 0.0035 17.0 0.1 0.038 13.7 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 KIR65483.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 1 0 1 1 1 0 MCM P-loop domain RuvB_N PF05496.12 KIR65483.1 - 0.028 14.2 0.1 0.29 10.9 0.1 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIR65483.1 - 0.04 14.3 0.9 0.09 13.2 0.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain VWA_2 PF13519.6 KIR65484.1 - 4.3e-19 69.1 0.0 9.2e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIR65484.1 - 2.1e-17 63.9 0.0 2.9e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 KIR65484.1 - 1.1e-08 35.3 7.4 2e-08 34.5 7.4 1.4 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal DUF1194 PF06707.11 KIR65484.1 - 0.008 15.4 2.6 0.041 13.1 2.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1194) SPC12 PF06645.13 KIR65484.1 - 0.01 15.9 0.1 11 6.2 0.0 3.0 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Neurensin PF14927.6 KIR65484.1 - 0.013 15.2 0.4 0.086 12.6 0.4 2.3 1 1 0 1 1 1 0 Neurensin VWA_3 PF13768.6 KIR65484.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF3522 PF12036.8 KIR65484.1 - 0.12 12.7 0.2 0.47 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) DUF4131 PF13567.6 KIR65484.1 - 1.6 8.4 5.0 0.56 9.8 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Trypsin_2 PF13365.6 KIR65485.1 - 3.6e-34 118.8 4.1 5.8e-34 118.2 4.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KIR65485.1 - 5.4e-11 42.7 0.1 8.8e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.13 KIR65485.1 - 0.0049 16.1 2.7 0.58 9.3 0.6 2.3 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 KIR65485.1 - 0.011 14.4 0.2 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S29 PF02907.15 KIR65485.1 - 0.028 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.21 KIR65485.1 - 0.19 11.6 0.3 0.32 10.8 0.3 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Metal_resist PF13801.6 KIR65486.1 - 0.39 10.9 6.4 4.7 7.4 1.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance FtsX PF02687.21 KIR65486.1 - 3.7 8.1 5.7 15 6.1 5.7 1.8 1 1 0 1 1 1 0 FtsX-like permease family RF-1 PF00472.20 KIR65487.1 - 1.1e-19 70.5 0.0 1.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain CBM_2 PF00553.19 KIR65488.1 - 4.6e-29 100.7 6.4 4.6e-29 100.7 6.4 2.2 3 0 0 3 3 3 1 Cellulose binding domain Lipase_GDSL_2 PF13472.6 KIR65488.1 - 1.6e-20 74.3 0.7 1.6e-20 74.3 0.7 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR65488.1 - 1.9e-08 34.5 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KIR65488.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CARDB PF07705.11 KIR65488.1 - 0.026 14.8 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 CARDB OSK PF17182.4 KIR65488.1 - 0.058 12.6 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 OSK domain CBM49 PF09478.10 KIR65488.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 Lipase_GDSL_lke PF16255.5 KIR65488.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase TALPID3 PF15324.6 KIR65488.1 - 6.8 4.2 11.7 9.2 3.8 11.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DotU PF09850.9 KIR65490.1 - 1.8 8.2 4.3 1.8 8.2 0.3 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU CcmD PF04995.14 KIR65490.1 - 5.8 7.1 10.0 4.4 7.5 2.2 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) FAA_hydrolase PF01557.18 KIR65491.1 - 3.8e-63 213.1 0.0 4.4e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 KIR65491.1 - 1.8e-12 47.9 1.4 4.1e-12 46.8 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2437) IclR PF01614.18 KIR65492.1 - 1.8e-20 73.1 0.7 1.5e-18 66.8 0.1 3.0 2 1 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR65492.1 - 5.7e-09 35.6 2.3 1.1e-08 34.8 0.4 2.4 3 0 0 3 3 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR65492.1 - 0.093 12.6 0.2 0.093 12.6 0.2 3.0 4 0 0 4 4 4 0 MarR family Aconitase PF00330.20 KIR65493.1 - 3.4e-160 534.0 0.0 3.8e-160 533.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 KIR65493.1 - 0.079 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Aconitase_C PF00694.19 KIR65494.1 - 3.4e-27 95.4 0.0 9.8e-27 93.9 0.0 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain Bac_DNA_binding PF00216.21 KIR65495.1 - 8.4e-24 83.6 1.0 8.4e-24 83.6 1.0 2.6 2 1 1 3 3 3 1 Bacterial DNA-binding protein HU-HIG PF18291.1 KIR65495.1 - 0.00031 20.8 0.0 0.00075 19.6 0.0 1.7 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif TFIIA PF03153.13 KIR65495.1 - 9.6 6.1 16.7 12 5.8 16.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.23 KIR65496.1 - 1.2e-13 51.1 0.3 2.2e-13 50.2 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NUDIX PF00293.28 KIR65497.1 - 1.5e-16 60.6 0.2 2.7e-16 59.8 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain His_Phos_1 PF00300.22 KIR65497.1 - 3.6e-10 39.9 0.3 7.1e-10 38.9 0.3 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CSD PF00313.22 KIR65498.1 - 0.065 13.1 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain TruB-C_2 PF09157.11 KIR65498.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal Acyltransferase PF01553.21 KIR65499.1 - 8.6e-28 96.6 0.0 1.1e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 KIR65499.1 - 0.0019 17.2 0.0 0.073 12.0 0.0 2.1 1 1 1 2 2 2 2 Diacylglycerol acyltransferase Lip_A_acyltrans PF03279.13 KIR65499.1 - 0.037 13.2 0.0 0.094 11.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase DUF397 PF04149.12 KIR65500.1 - 3e-24 84.8 0.6 4.2e-24 84.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KIR65501.1 - 1.6e-15 57.2 5.2 2.5e-15 56.6 3.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65501.1 - 3.1e-13 49.6 0.1 1.7e-12 47.2 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR65501.1 - 2.9e-08 33.6 0.0 5.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR65501.1 - 0.0031 17.3 1.6 0.013 15.4 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR65501.1 - 0.088 12.6 0.4 0.33 10.8 0.2 2.0 1 1 0 1 1 1 0 Homeodomain-like domain Sigma54_DBD PF04552.13 KIR65501.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain DUF5575 PF17738.1 KIR65502.1 - 0.086 11.9 0.2 0.096 11.7 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Dala_Dala_lig_C PF07478.13 KIR65504.1 - 2.5e-64 216.6 0.0 3.2e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 KIR65504.1 - 1.2e-30 106.0 0.0 2.1e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 KIR65504.1 - 2.8e-09 36.8 0.0 3.3e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KIR65504.1 - 0.00027 20.5 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KIR65504.1 - 0.00075 19.1 0.0 0.0026 17.4 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KIR65504.1 - 0.0018 18.4 0.0 0.025 14.7 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KIR65504.1 - 0.0089 15.3 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp TTL PF03133.15 KIR65504.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.4 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family DUF3515 PF12028.8 KIR65505.1 - 1.4e-17 63.8 8.4 2.3e-17 63.2 8.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3515) DUF1467 PF07330.12 KIR65505.1 - 0.32 10.9 0.1 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) AsnC_trans_reg PF01037.21 KIR65506.1 - 1e-09 38.2 0.1 1.2e-09 38.0 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 KIR65506.1 - 0.0086 16.1 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 1 NapD protein GYD PF08734.11 KIR65506.1 - 0.097 12.6 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 GYD domain AIRS PF00586.24 KIR65507.1 - 4.9e-22 78.4 5.5 7.4e-22 77.8 3.8 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 KIR65507.1 - 9.4e-07 29.1 3.1 1.5e-06 28.5 0.2 2.6 2 2 1 3 3 3 1 AIR synthase related protein, C-terminal domain Acetyltransf_1 PF00583.25 KIR65508.1 - 1.7e-14 54.1 0.1 2.1e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR65508.1 - 1.4e-10 41.2 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65508.1 - 5.1e-10 39.6 0.0 7.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65508.1 - 5.7e-06 26.2 0.0 8.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIR65508.1 - 0.0002 22.0 0.0 0.00022 21.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65508.1 - 0.00032 20.7 0.1 0.00086 19.4 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KIR65508.1 - 0.034 14.2 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIR65508.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LAL_C2 PF18603.1 KIR65509.1 - 5.7e-23 80.9 3.8 1.6e-22 79.5 3.8 1.8 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 KIR65509.1 - 1.5e-15 57.2 0.0 2.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KIR65509.1 - 0.00018 21.4 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KIR65509.1 - 0.00029 20.9 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KIR65509.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ribosomal_L28 PF00830.19 KIR65510.1 - 2.1e-23 82.3 3.2 2.5e-23 82.0 3.2 1.0 1 0 0 1 1 1 1 Ribosomal L28 family Epiglycanin_C PF14654.6 KIR65510.1 - 0.045 13.8 0.2 0.052 13.6 0.2 1.1 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Dak1_2 PF13684.6 KIR65511.1 - 4.6e-85 285.4 0.0 5.9e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Dak2 PF02734.17 KIR65511.1 - 2.2e-32 112.3 10.6 2.2e-32 112.3 10.6 2.1 2 0 0 2 2 2 1 DAK2 domain TrkA_N PF02254.18 KIR65511.1 - 0.062 13.6 1.0 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Ribosomal_S28e PF01200.18 KIR65511.1 - 0.07 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S28e Helicase_C PF00271.31 KIR65512.1 - 1.4e-21 76.9 0.0 2e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KIR65512.1 - 2.1e-14 53.7 0.0 3.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecG_wedge PF17191.4 KIR65512.1 - 6.9e-09 35.5 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 RecG wedge domain ResIII PF04851.15 KIR65512.1 - 6.6e-08 32.7 0.0 3.8e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 KIR65512.1 - 4.5e-05 23.3 0.1 9.8e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AAA_30 PF13604.6 KIR65512.1 - 0.024 14.4 5.9 0.1 12.3 5.9 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIR65512.1 - 0.088 13.1 0.1 0.44 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KIR65512.1 - 0.12 11.3 0.2 0.23 10.4 0.1 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Cons_hypoth95 PF03602.15 KIR65513.1 - 1.5e-50 171.4 0.0 1.7e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KIR65513.1 - 0.00078 18.9 0.0 0.00095 18.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RsmJ PF04378.13 KIR65513.1 - 0.0011 18.2 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ MethyltransfD12 PF02086.15 KIR65513.1 - 0.0034 17.1 0.2 0.41 10.3 0.0 2.1 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase TetR_C_6 PF13977.6 KIR65513.1 - 6.7 7.0 12.7 27 5.0 4.2 2.4 1 1 1 2 2 2 0 BetI-type transcriptional repressor, C-terminal CTP_transf_like PF01467.26 KIR65514.1 - 5.6e-23 81.7 0.0 6.5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 KIR65514.1 - 0.00018 21.2 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain Phage_int_SAM_6 PF18644.1 KIR65514.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Phage integrase SAM-like domain V-ATPase_G_2 PF16999.5 KIR65515.1 - 0.0012 19.2 9.9 0.042 14.3 2.9 2.4 1 1 1 2 2 2 2 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KIR65515.1 - 0.0019 18.3 11.2 0.056 13.5 10.3 2.1 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) DivIVA PF05103.13 KIR65515.1 - 0.13 12.3 3.8 1.8 8.6 3.8 2.3 1 1 0 1 1 1 0 DivIVA protein ERM PF00769.19 KIR65515.1 - 0.3 10.9 5.1 2.6 7.8 5.3 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family YceD PF02620.17 KIR65516.1 - 8.7e-30 103.3 0.4 1.1e-29 103.0 0.4 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Ribosomal_L32p PF01783.23 KIR65517.1 - 8.3e-25 86.8 5.4 8.9e-25 86.7 5.4 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-tcix PF14952.6 KIR65517.1 - 0.0034 16.9 2.3 0.027 14.1 0.2 2.2 2 0 0 2 2 2 1 Putative treble-clef, zinc-finger, Zn-binding zf-RanBP PF00641.18 KIR65517.1 - 0.021 14.2 3.9 1.6 8.1 0.6 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 KIR65517.1 - 0.069 12.6 6.4 4.5 6.8 6.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KIR65517.1 - 0.22 11.7 4.6 1.2 9.3 1.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Fapy_DNA_glyco PF01149.24 KIR65518.1 - 1.4e-36 125.6 0.1 2.5e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KIR65518.1 - 5.5e-26 90.4 0.0 8.9e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 KIR65518.1 - 6.5e-11 41.9 5.3 1.5e-10 40.7 5.3 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FbpA PF05833.11 KIR65518.1 - 0.00066 18.6 0.0 0.00084 18.2 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Auto_anti-p27 PF06677.12 KIR65518.1 - 0.076 13.2 1.4 0.17 12.1 1.4 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KIR65518.1 - 0.16 12.0 1.2 0.27 11.3 1.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Glyco_hydro_114 PF03537.13 KIR65519.1 - 1.4e-47 162.0 0.0 1.6e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 CAP PF00188.26 KIR65520.1 - 8.2e-21 75.2 1.3 8.2e-21 75.2 1.3 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ORC6 PF05460.13 KIR65520.1 - 6.5 5.9 8.8 12 5.1 8.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PikAIV_N PF18605.1 KIR65521.1 - 0.0016 18.0 0.4 0.0016 18.0 0.4 2.3 2 0 0 2 2 2 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Shugoshin_N PF07558.11 KIR65521.1 - 0.0037 17.1 0.1 0.005 16.7 0.1 1.2 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF1192 PF06698.11 KIR65521.1 - 0.01 15.8 2.9 0.014 15.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.6 KIR65521.1 - 0.011 15.8 2.4 0.014 15.5 2.4 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Filament PF00038.21 KIR65521.1 - 0.015 14.9 0.1 0.017 14.7 0.1 1.0 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 KIR65521.1 - 0.024 14.4 0.4 0.026 14.3 0.4 1.2 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 KIR65521.1 - 0.025 15.0 0.4 0.039 14.4 0.4 1.4 1 1 0 1 1 1 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 KIR65521.1 - 0.03 14.5 0.2 0.034 14.4 0.2 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 KIR65521.1 - 0.035 12.7 2.0 0.035 12.6 2.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TSC22 PF01166.18 KIR65521.1 - 0.035 14.4 0.2 0.041 14.2 0.2 1.1 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KIR65521.1 - 0.037 14.1 0.1 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 bZIP transcription factor CCDC158 PF15921.5 KIR65521.1 - 0.041 11.7 0.1 0.045 11.6 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Pox_A_type_inc PF04508.12 KIR65521.1 - 0.093 12.6 0.5 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HALZ PF02183.18 KIR65521.1 - 0.12 12.6 0.3 0.52 10.6 0.1 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper kleA_kleC PF17383.2 KIR65521.1 - 0.24 11.7 3.7 0.35 11.2 3.4 1.5 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A HAD_2 PF13419.6 KIR65522.1 - 5e-11 43.0 0.0 7.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR65522.1 - 2.7e-10 40.9 2.1 6.1e-10 39.7 2.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR65522.1 - 0.00017 21.6 0.0 0.00054 20.0 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIR65522.1 - 0.035 14.5 0.2 0.05 14.0 0.2 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIR65522.1 - 0.12 12.5 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF664 PF04978.12 KIR65523.1 - 7e-44 149.9 0.6 8e-44 149.7 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR65523.1 - 2.7e-07 31.1 2.4 3.3e-07 30.9 2.4 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 KIR65523.1 - 0.0016 18.4 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 DinB family MarR_2 PF12802.7 KIR65524.1 - 9.4e-15 54.3 0.6 2.1e-14 53.1 0.6 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KIR65524.1 - 2.5e-13 49.7 0.1 4.1e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR65524.1 - 2.5e-10 40.7 0.1 4.1e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KIR65524.1 - 2.3e-07 30.5 0.4 5.8e-07 29.2 0.4 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 KIR65524.1 - 2.6e-06 27.4 0.4 2.6e-06 27.4 0.4 2.2 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_34 PF13601.6 KIR65524.1 - 6.9e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 KIR65524.1 - 1.6e-05 24.7 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 KIR65524.1 - 0.0001 21.8 0.1 0.00021 20.8 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 KIR65524.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_DeoR PF08220.12 KIR65524.1 - 0.00027 20.6 0.1 0.0006 19.5 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 KIR65524.1 - 0.00084 19.2 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 KIR65524.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KIR65524.1 - 0.0026 17.7 0.2 0.0058 16.6 0.2 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_1 PF00126.27 KIR65524.1 - 0.01 15.8 1.2 0.094 12.7 0.8 2.7 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 KIR65524.1 - 0.013 15.4 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain DprA_WH PF17782.1 KIR65524.1 - 0.029 14.5 0.2 0.049 13.8 0.2 1.4 1 0 0 1 1 1 0 DprA winged helix domain Fe_dep_repress PF01325.19 KIR65524.1 - 0.038 14.2 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Phage_CI_repr PF07022.13 KIR65524.1 - 0.042 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Mga PF05043.13 KIR65524.1 - 0.045 14.4 0.0 0.067 13.8 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain GntR PF00392.21 KIR65524.1 - 0.05 13.3 0.2 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family PadR PF03551.14 KIR65524.1 - 0.057 13.4 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_3 PF01381.22 KIR65524.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HrcA_DNA-bdg PF03444.15 KIR65524.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_10 PF04967.12 KIR65524.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain PhoD PF09423.10 KIR65525.1 - 7.6e-17 61.3 0.8 2.6e-14 53.0 1.4 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase SRP54 PF00448.22 KIR65526.1 - 1.2e-71 240.4 0.8 1.5e-71 240.1 0.8 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KIR65526.1 - 2.8e-11 43.5 0.3 6.7e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KIR65526.1 - 1.1e-05 25.3 1.3 2e-05 24.4 1.3 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIR65526.1 - 8.8e-05 22.6 0.0 0.00025 21.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KIR65526.1 - 0.00017 22.0 0.8 0.00036 21.0 0.2 1.8 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 KIR65526.1 - 0.00019 20.8 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 KIR65526.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIR65526.1 - 0.017 14.8 0.2 0.067 12.9 0.1 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.6 KIR65526.1 - 0.037 14.4 0.8 0.065 13.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIR65526.1 - 0.039 14.4 0.1 0.039 14.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIR65526.1 - 0.044 13.7 0.9 0.063 13.2 0.1 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 KIR65526.1 - 0.05 13.4 0.2 0.095 12.5 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KIR65526.1 - 0.13 12.5 0.7 0.18 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_27 PF13514.6 KIR65526.1 - 0.13 11.8 0.0 2.5 7.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KIR65526.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KIR65526.1 - 0.15 12.0 1.3 0.39 10.6 0.5 2.0 2 0 0 2 2 2 0 NTPase AAA PF00004.29 KIR65526.1 - 0.29 11.5 1.4 0.71 10.3 0.2 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KIR65526.1 - 0.37 10.4 2.0 12 5.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APH PF01636.23 KIR65527.1 - 1.6e-14 54.4 8.1 3.3e-13 50.1 7.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIR65527.1 - 1.3e-05 24.9 0.0 5.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase HNH_3 PF13392.6 KIR65527.1 - 0.0028 17.4 1.4 0.066 13.0 0.4 2.5 2 0 0 2 2 2 1 HNH endonuclease Ammonium_transp PF00909.21 KIR65528.1 - 2.2e-125 418.5 38.4 2.6e-125 418.3 38.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family P-II PF00543.22 KIR65529.1 - 1.1e-38 132.0 2.1 1.2e-38 131.8 2.1 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 KIR65529.1 - 0.023 14.8 0.1 0.031 14.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) HD PF01966.22 KIR65530.1 - 9.5e-10 38.8 0.4 2.1e-09 37.6 0.4 1.6 1 0 0 1 1 1 1 HD domain ACT PF01842.25 KIR65530.1 - 6.2e-07 29.1 2.3 0.05 13.4 0.0 3.7 3 0 0 3 3 3 2 ACT domain GlnD_UR_UTase PF08335.11 KIR65530.1 - 2.1e-05 24.7 1.2 0.071 13.2 0.0 2.7 1 1 1 2 2 2 2 GlnD PII-uridylyltransferase ACT_4 PF13291.6 KIR65530.1 - 0.00095 19.7 0.0 2.5 8.7 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 KIR65530.1 - 0.02 14.9 0.6 5.3 7.1 0.0 2.8 2 0 0 2 2 2 0 ACT domain SRP54 PF00448.22 KIR65531.1 - 3e-69 232.6 0.0 4.7e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KIR65531.1 - 1.3e-31 109.1 0.8 3.5e-31 107.7 0.8 1.8 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 KIR65531.1 - 6.9e-22 77.5 0.2 1.6e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 KIR65531.1 - 5.3e-07 29.7 0.6 2.6e-06 27.5 0.1 2.4 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 KIR65531.1 - 9.6e-06 25.3 0.6 5.6e-05 22.8 0.5 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KIR65531.1 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR65531.1 - 0.00052 19.8 1.3 0.0013 18.4 1.3 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIR65531.1 - 0.00059 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KIR65531.1 - 0.00076 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KIR65531.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KIR65531.1 - 0.0021 18.0 0.3 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 NTPase ArsA_ATPase PF02374.15 KIR65531.1 - 0.0058 15.9 0.6 0.092 11.9 0.0 2.6 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KIR65531.1 - 0.0064 16.4 0.0 0.019 14.9 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIR65531.1 - 0.0068 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 KIR65531.1 - 0.0071 16.2 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 KIR65531.1 - 0.0083 16.2 1.3 0.063 13.4 0.4 2.6 2 1 0 2 2 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIR65531.1 - 0.0091 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_16 PF13191.6 KIR65531.1 - 0.01 16.2 0.0 0.04 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 KIR65531.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase CLP1_P PF16575.5 KIR65531.1 - 0.013 15.3 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 KIR65531.1 - 0.031 14.2 0.6 0.058 13.3 0.6 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 KIR65531.1 - 0.034 13.6 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_26 PF13500.6 KIR65531.1 - 0.039 13.8 0.4 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIR65531.1 - 0.074 12.6 4.2 1.6 8.3 2.1 2.9 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIR65531.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KIR65531.1 - 0.099 13.1 0.0 0.33 11.4 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIR65531.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIR65531.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIR65531.1 - 0.14 11.9 0.0 0.62 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 KIR65531.1 - 0.21 11.0 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Uma2 PF05685.12 KIR65532.1 - 5.6e-27 94.4 0.5 7.3e-27 94.0 0.5 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease Amidohydro_1 PF01979.20 KIR65533.1 - 5.1e-14 52.3 0.3 3e-13 49.8 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIR65533.1 - 0.00011 21.8 14.3 0.018 14.5 6.8 3.3 1 1 1 2 2 2 2 Amidohydrolase family TetR_C_35 PF18556.1 KIR65534.1 - 5e-29 100.5 8.0 1.1e-28 99.5 8.0 1.5 1 0 0 1 1 1 1 Bacterial Tetracyclin repressor, C-terminal domain TetR_N PF00440.23 KIR65534.1 - 3.5e-11 42.7 0.1 7.5e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 KIR65534.1 - 0.021 14.6 0.1 0.063 13.1 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DUF883 PF05957.13 KIR65534.1 - 0.068 13.8 0.8 0.068 13.8 0.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HTH_28 PF13518.6 KIR65534.1 - 0.15 12.2 0.9 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain TetR_C_15 PF17918.1 KIR65534.1 - 3.9 8.3 14.7 0.76 10.6 1.7 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HGTP_anticodon PF03129.20 KIR65535.1 - 2.1e-14 53.4 0.0 4.5e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIR65535.1 - 2.3e-11 44.0 0.0 3.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TPR_12 PF13424.6 KIR65536.1 - 7.1e-55 183.2 72.0 5.5e-14 52.2 3.0 7.2 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 KIR65536.1 - 1.3e-46 155.3 49.5 7.4e-07 28.9 0.4 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TIR_2 PF13676.6 KIR65536.1 - 0.00052 20.6 0.0 0.003 18.2 0.0 2.3 3 0 0 3 3 3 1 TIR domain NB-ARC PF00931.22 KIR65536.1 - 0.00053 19.3 0.0 0.00092 18.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.6 KIR65536.1 - 0.0026 18.0 0.8 31 5.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIR65536.1 - 0.0059 16.4 2.8 5.1 7.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 KIR65536.1 - 0.052 13.9 0.1 0.052 13.9 0.1 4.1 3 2 0 3 3 3 0 AAA ATPase domain TPR_7 PF13176.6 KIR65536.1 - 0.8 9.9 29.0 3 8.1 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIR65538.1 - 2.2e-09 37.5 7.6 1.2e-05 25.5 0.3 7.7 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIR65538.1 - 6.8e-07 29.0 39.4 0.04 13.8 0.7 8.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIR65538.1 - 0.0033 17.5 0.3 4.3 7.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIR65538.1 - 0.0098 16.4 44.1 4.8 7.8 1.4 11.1 8 2 3 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIR65538.1 - 1.7 8.4 5.2 57 3.5 0.2 4.8 6 0 0 6 6 6 0 TPR repeat TPR_2 PF07719.17 KIR65538.1 - 8.1 6.8 23.7 1.3 9.3 0.4 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat AAA_5 PF07728.14 KIR65539.1 - 2e-08 34.3 0.0 5.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIR65539.1 - 2.6e-06 27.9 0.2 3.4e-05 24.3 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIR65539.1 - 0.00024 21.5 2.1 0.0028 18.1 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIR65539.1 - 0.00026 21.3 0.1 0.0032 17.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIR65539.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIR65539.1 - 0.0021 18.2 0.0 0.0045 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KIR65539.1 - 0.0026 17.7 0.1 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KIR65539.1 - 0.004 17.7 0.0 0.0072 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KIR65539.1 - 0.005 16.8 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 1 1 NTPase Sigma54_activat PF00158.26 KIR65539.1 - 0.0085 15.8 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KIR65539.1 - 0.0086 16.4 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KIR65539.1 - 0.0099 15.6 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 KIR65539.1 - 0.018 14.8 0.0 0.078 12.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KIR65539.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KIR65539.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIR65539.1 - 0.044 13.9 0.0 0.085 12.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ArsA_ATPase PF02374.15 KIR65539.1 - 0.062 12.5 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase TIP49 PF06068.13 KIR65539.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KIR65539.1 - 0.087 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIR65539.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIR65539.1 - 0.13 12.3 0.0 0.48 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KIR65539.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ParA PF10609.9 KIR65539.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ABC_tran PF00005.27 KIR65539.1 - 0.17 12.4 0.1 0.45 11.0 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_19 PF13245.6 KIR65539.1 - 0.19 12.1 0.1 0.68 10.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIR65539.1 - 0.24 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 KIR65539.1 - 0.25 11.1 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 KIR65539.1 - 0.29 10.6 0.0 0.51 9.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Trypsin_2 PF13365.6 KIR65540.1 - 5.9e-14 53.2 1.0 1.2e-13 52.2 1.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF402 PF04167.13 KIR65541.1 - 5.4e-15 55.3 2.8 1.2e-14 54.2 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF402) Ribosomal_S16 PF00886.19 KIR65542.1 - 1.8e-23 82.3 0.1 3.7e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 KH_4 PF13083.6 KIR65543.1 - 2.2e-18 65.9 0.1 2.5e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KIR65543.1 - 0.0023 17.7 0.5 0.0028 17.5 0.5 1.2 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 KIR65543.1 - 0.021 14.9 0.6 0.037 14.1 0.6 1.4 1 0 0 1 1 1 0 NusA-like KH domain KH_1 PF00013.29 KIR65543.1 - 0.021 14.6 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 KH domain RimM PF01782.18 KIR65544.1 - 4.2e-23 81.4 0.0 7.8e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 KIR65544.1 - 1.8e-07 31.1 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 PRC-barrel domain tRNA_m1G_MT PF01746.21 KIR65545.1 - 2.6e-63 213.3 0.0 3e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L19 PF01245.20 KIR65546.1 - 1.8e-46 156.7 2.7 2e-46 156.5 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_S24 PF00717.23 KIR65547.1 - 1.8e-18 66.3 1.5 3.8e-10 39.6 0.1 2.7 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 KIR65547.1 - 1.7e-08 34.4 0.0 4.1e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 MaoC_dehydrat_N PF13452.6 KIR65547.1 - 0.018 15.2 0.4 7.9 6.6 0.1 2.8 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase Peptidase_S24 PF00717.23 KIR65548.1 - 7.6e-18 64.2 0.1 1.2e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIR65548.1 - 2e-05 24.4 0.0 4.5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 RNase_HII PF01351.18 KIR65549.1 - 3.9e-36 124.8 0.0 5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF2469 PF10611.9 KIR65550.1 - 2.6e-53 178.8 7.0 2.9e-53 178.6 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) Aminotran_5 PF00266.19 KIR65551.1 - 1e-22 80.7 0.0 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIR65551.1 - 4.2e-08 32.9 1.7 1.3e-07 31.3 1.7 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIR65551.1 - 1.6e-07 30.2 0.0 2.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIR65551.1 - 3.4e-06 26.5 0.0 5.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Phage_integrase PF00589.22 KIR65552.1 - 8.2e-39 133.1 0.0 2.4e-38 131.6 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KIR65552.1 - 2.2e-14 53.5 1.8 2.4e-14 53.4 0.4 1.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KIR65552.1 - 0.14 12.7 0.0 0.41 11.1 0.0 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DNA_processg_A PF02481.15 KIR65553.1 - 4e-63 212.5 0.9 4.6e-63 212.3 0.0 1.5 2 0 0 2 2 2 1 DNA recombination-mediator protein A LDcluster4 PF18306.1 KIR65553.1 - 3.8e-08 33.1 0.8 3.8e-08 33.1 0.8 1.7 2 0 0 2 2 2 1 SLOG cluster4 family DprA_WH PF17782.1 KIR65553.1 - 1e-05 25.6 4.1 1e-05 25.6 4.1 2.6 2 0 0 2 2 2 1 DprA winged helix domain HTH_20 PF12840.7 KIR65553.1 - 0.011 15.8 0.6 0.048 13.7 0.6 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 KIR65553.1 - 0.012 15.4 0.0 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_29 PF13551.6 KIR65553.1 - 0.014 15.4 4.8 11 6.1 0.1 4.1 4 0 0 4 4 4 0 Winged helix-turn helix HTH_36 PF13730.6 KIR65553.1 - 0.037 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 KIR65553.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 KIR65553.1 - 0.058 13.2 0.5 0.058 13.2 0.5 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR65553.1 - 1.4 8.9 11.5 0.18 11.7 0.9 3.8 3 1 0 3 3 3 0 MarR family Mg_chelatase PF01078.21 KIR65554.1 - 2e-81 272.4 0.0 2.9e-81 271.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 KIR65554.1 - 3.5e-39 133.4 0.0 5.5e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 KIR65554.1 - 1.3e-24 86.7 0.2 7.8e-24 84.1 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal Lon_C PF05362.13 KIR65554.1 - 9.5e-07 28.6 0.3 1.6e-06 27.8 0.3 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_5 PF07728.14 KIR65554.1 - 1e-05 25.5 0.0 0.049 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIR65554.1 - 0.00011 22.5 0.0 0.00049 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 KIR65554.1 - 0.00013 21.2 0.0 0.00048 19.3 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 KIR65554.1 - 0.0041 17.5 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 KIR65554.1 - 0.0047 16.6 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 KIR65554.1 - 0.018 15.5 0.0 0.07 13.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIR65554.1 - 0.023 14.4 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KIR65554.1 - 0.026 14.3 0.0 0.62 9.8 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KIR65554.1 - 0.055 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR65554.1 - 0.088 13.0 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2285 PF10074.9 KIR65554.1 - 0.31 11.7 5.3 4.7 7.9 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2285) UPF0102 PF02021.17 KIR65555.1 - 3.3e-26 91.3 0.0 4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NucS PF01939.16 KIR65555.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease NucS Ribosomal_S2 PF00318.20 KIR65557.1 - 1.8e-95 318.3 0.0 2e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 EF_TS PF00889.19 KIR65558.1 - 1.6e-64 217.4 0.6 2.2e-64 216.9 0.6 1.2 1 0 0 1 1 1 1 Elongation factor TS DUF348 PF03990.14 KIR65558.1 - 0.027 14.2 1.0 0.62 9.8 0.1 2.7 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain AA_kinase PF00696.28 KIR65559.1 - 1.9e-26 93.1 0.3 2.3e-26 92.9 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family TP_methylase PF00590.20 KIR65559.1 - 0.0041 17.1 1.0 2.9 7.8 0.1 3.0 1 1 1 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases RRF PF01765.19 KIR65560.1 - 1.1e-57 194.5 0.1 1.4e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.13 KIR65560.1 - 1.6 9.4 5.8 1.6 9.4 2.4 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CTP_transf_1 PF01148.20 KIR65561.1 - 4e-52 177.6 10.9 5e-52 177.3 10.9 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family PgpA PF04608.13 KIR65561.1 - 0.15 12.1 2.8 12 5.9 0.2 2.5 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A DUF3488 PF11992.8 KIR65561.1 - 0.47 9.4 8.9 0.81 8.6 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Radical_SAM PF04055.21 KIR65562.1 - 4e-18 66.4 0.0 8.6e-18 65.3 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KIR65562.1 - 0.035 14.2 0.0 0.099 12.8 0.0 1.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain DivIVA PF05103.13 KIR65563.1 - 2e-10 40.8 2.5 0.013 15.6 0.1 4.1 4 0 0 4 4 4 4 DivIVA protein DUF2631 PF10939.8 KIR65564.1 - 1.9e-13 50.1 0.1 2.6e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2631) SdpI PF13630.6 KIR65564.1 - 0.039 14.1 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family MLTD_N PF06474.12 KIR65564.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 MltD lipid attachment motif Rieske PF00355.26 KIR65565.1 - 1.7e-08 34.3 0.1 3.5e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Lactamase_B_3 PF13483.6 KIR65565.1 - 3e-06 27.2 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KIR65565.1 - 3.8e-05 23.3 0.1 6.6e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Complex1_LYR_1 PF13232.6 KIR65565.1 - 0.086 13.4 0.9 2.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Complex1_LYR-like DUF1211 PF06736.11 KIR65566.1 - 5.7e-25 87.6 3.7 5.7e-25 87.6 3.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1211) AAA PF00004.29 KIR65567.1 - 2.4e-28 99.2 0.0 4.7e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIR65567.1 - 1.4e-06 28.8 3.8 0.00013 22.4 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIR65567.1 - 0.00086 19.5 0.9 0.0081 16.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIR65567.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KIR65567.1 - 0.0021 18.4 0.2 0.4 10.9 0.1 3.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 KIR65567.1 - 0.01 15.9 0.1 0.07 13.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Cas_Cas2CT1978 PF09707.10 KIR65567.1 - 0.041 14.0 0.1 0.41 10.8 0.1 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) AAA_2 PF07724.14 KIR65567.1 - 0.047 13.8 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 KIR65567.1 - 0.057 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 KIR65567.1 - 0.067 12.3 0.0 0.19 10.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Peptidase_C14 PF00656.22 KIR65570.1 - 2.8e-19 70.0 0.0 4.2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Amino_oxidase PF01593.24 KIR65571.1 - 1.3e-10 41.2 7.7 3e-06 26.8 0.0 2.6 3 1 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR65571.1 - 9.9e-10 38.5 0.1 4.1e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR65571.1 - 5.2e-08 32.9 8.9 0.00054 19.6 3.5 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR65571.1 - 4.3e-07 29.4 5.9 4.7e-05 22.7 4.6 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIR65571.1 - 1.9e-06 27.5 2.1 2.3e-05 23.9 1.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIR65571.1 - 2.9e-05 23.4 0.2 5.1e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KIR65571.1 - 0.00016 21.1 2.9 0.00029 20.2 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR65571.1 - 0.00018 20.9 0.2 0.0032 16.7 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR65571.1 - 0.002 18.6 0.7 1.3 9.6 1.8 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR65571.1 - 0.0078 15.0 1.2 0.087 11.5 2.8 1.8 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KIR65571.1 - 0.01 14.7 0.7 0.17 10.7 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 KIR65571.1 - 0.01 14.9 0.7 0.025 13.7 0.8 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIR65571.1 - 0.027 13.5 5.3 2.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KIR65571.1 - 0.14 11.7 0.3 0.22 11.1 0.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KIR65571.1 - 0.29 10.4 1.4 0.4 9.9 1.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MMPL PF03176.15 KIR65572.1 - 6.1e-83 278.5 42.4 1e-55 189.0 17.6 2.5 2 1 0 2 2 2 2 MMPL family ACR_tran PF00873.19 KIR65572.1 - 1.3e-07 29.7 9.9 1.3e-07 29.7 9.9 1.9 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Sterol-sensing PF12349.8 KIR65572.1 - 0.48 10.3 14.4 0.15 11.9 2.9 3.2 2 1 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Clostridium_P47 PF06597.11 KIR65572.1 - 0.98 8.1 3.5 1.7 7.3 3.5 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein Patched PF02460.18 KIR65572.1 - 8.7 4.3 12.9 0.22 9.5 5.2 1.9 2 0 0 2 2 2 0 Patched family DUF839 PF05787.13 KIR65573.1 - 1e-32 114.0 5.3 3.5e-12 46.3 0.0 4.7 1 1 1 4 4 4 4 Bacterial protein of unknown function (DUF839) PD40 PF07676.12 KIR65573.1 - 9e-08 31.9 0.1 9e-08 31.9 0.1 2.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat VCBS PF13517.6 KIR65574.1 - 2.2e-11 44.2 14.4 1.4e-05 25.6 0.7 5.5 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KIR65574.1 - 0.0099 16.0 25.5 0.18 11.9 0.2 5.3 5 0 0 5 5 5 3 FG-GAP repeat HTH_31 PF13560.6 KIR65575.1 - 6.5e-15 55.2 0.1 6.5e-15 55.2 0.1 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR65575.1 - 0.022 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KIR65575.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.6 KIR65575.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF397 PF04149.12 KIR65576.1 - 1.5e-21 76.2 0.6 1.7e-21 76.0 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Virul_fac_BrkB PF03631.15 KIR65577.1 - 2.9e-19 69.7 22.4 3.2e-19 69.5 22.4 1.0 1 0 0 1 1 1 1 Virulence factor BrkB RhodobacterPufX PF11511.8 KIR65578.1 - 7.4 6.3 10.5 2 8.1 6.2 2.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Uma2 PF05685.12 KIR65579.1 - 6e-17 61.7 0.0 7.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease DXP_reductoisom PF02670.16 KIR65580.1 - 5.4e-38 130.6 0.1 1.4e-37 129.3 0.1 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 KIR65580.1 - 5.5e-38 129.0 0.0 1.4e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXPR_C PF13288.6 KIR65580.1 - 1.7e-31 108.8 0.0 3e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Peptidase_M50 PF02163.22 KIR65581.1 - 1.5e-45 155.5 0.0 2.1e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 KIR65581.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KIR65581.1 - 3.3e-08 33.2 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KIR65581.1 - 0.0016 18.8 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GcpE PF04551.14 KIR65582.1 - 3.4e-133 444.1 0.1 4.3e-133 443.7 0.1 1.0 1 0 0 1 1 1 1 GcpE protein MR_MLE_C PF13378.6 KIR65582.1 - 0.02 14.5 0.4 2.8 7.5 0.1 2.5 1 1 2 3 3 3 0 Enolase C-terminal domain-like zf-RING_7 PF02591.15 KIR65582.1 - 0.092 13.0 0.1 0.27 11.4 0.1 1.9 1 0 0 1 1 1 0 C4-type zinc ribbon domain PadR PF03551.14 KIR65583.1 - 6e-23 80.6 0.0 2.2e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family AphA_like PF14557.6 KIR65583.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator RTP PF02334.16 KIR65583.1 - 0.023 15.4 0.0 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 Replication terminator protein HTH_32 PF13565.6 KIR65583.1 - 0.058 14.0 4.7 2.2 8.9 0.2 2.8 1 1 2 3 3 3 0 Homeodomain-like domain ABC_tran PF00005.27 KIR65584.1 - 1.5e-50 171.3 0.0 2.6e-26 92.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIR65584.1 - 9.6e-16 58.2 0.3 1.2e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 KIR65584.1 - 1.1e-09 38.9 6.6 8.5e-05 23.0 1.3 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KIR65584.1 - 2.1e-08 33.9 0.0 0.42 10.0 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR65584.1 - 3e-08 33.3 0.3 0.003 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIR65584.1 - 7e-08 32.8 1.4 0.024 14.9 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KIR65584.1 - 1.2e-06 28.6 0.0 0.0026 17.6 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIR65584.1 - 3e-06 27.9 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIR65584.1 - 3.1e-05 24.0 1.8 0.24 11.5 0.0 3.0 4 0 0 4 4 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR65584.1 - 3.5e-05 23.8 0.2 0.33 10.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 KIR65584.1 - 0.00013 22.0 0.4 0.74 9.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KIR65584.1 - 0.00026 21.2 0.4 0.0013 18.8 0.1 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 KIR65584.1 - 0.00035 20.7 0.3 0.23 11.5 0.1 2.2 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 KIR65584.1 - 0.00039 19.8 0.0 0.32 10.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 KIR65584.1 - 0.00043 19.8 0.3 0.52 9.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KIR65584.1 - 0.00044 20.4 2.8 0.85 9.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KIR65584.1 - 0.00051 19.8 9.1 0.036 13.8 1.1 3.4 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 KIR65584.1 - 0.00067 19.3 0.4 1.1 8.8 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KIR65584.1 - 0.00076 20.0 0.1 2.4 8.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_PrkA PF08298.11 KIR65584.1 - 0.00077 18.5 0.1 0.013 14.4 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA PF00004.29 KIR65584.1 - 0.0009 19.7 0.0 0.75 10.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KIR65584.1 - 0.0022 17.1 0.0 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 KIR65584.1 - 0.0026 17.7 0.7 2.4 8.1 0.2 2.5 2 0 0 2 2 2 2 NACHT domain AAA_27 PF13514.6 KIR65584.1 - 0.0051 16.4 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIR65584.1 - 0.012 16.0 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KIR65584.1 - 0.013 14.9 0.1 4.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KIR65584.1 - 0.015 14.4 0.2 1.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 KIR65584.1 - 0.016 15.2 2.4 4.4 7.3 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KIR65584.1 - 0.021 14.4 10.5 0.5 9.9 0.0 3.9 4 1 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 KIR65584.1 - 0.027 14.2 0.1 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 KIR65584.1 - 0.035 14.3 0.7 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KIR65584.1 - 0.037 13.9 0.1 5.2 6.9 0.0 2.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 KIR65584.1 - 0.043 13.2 0.8 5 6.4 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 KIR65584.1 - 0.051 13.3 0.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.7 KIR65584.1 - 0.051 12.5 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 KIR65584.1 - 0.052 13.3 0.8 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KIR65584.1 - 0.077 12.7 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIR65584.1 - 0.11 12.2 0.0 6.1 6.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain dNK PF01712.19 KIR65584.1 - 0.15 11.9 0.4 12 5.7 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 KIR65584.1 - 0.16 11.7 0.4 18 5.0 0.1 2.7 3 0 0 3 3 3 0 Cytidylate kinase ATPase_2 PF01637.18 KIR65584.1 - 0.18 11.7 0.0 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 KIR65584.1 - 0.2 11.1 0.3 5.3 6.6 0.0 2.5 3 0 0 3 3 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 KIR65584.1 - 0.41 9.8 1.4 3.4 6.8 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain Oxidored_FMN PF00724.20 KIR65585.1 - 3.4e-70 237.0 0.0 4.2e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Thiolase_N PF00108.23 KIR65586.1 - 1.3e-72 244.3 0.1 1.8e-72 243.8 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR65586.1 - 1.8e-41 140.6 0.2 3.1e-41 139.9 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR65586.1 - 5.9e-05 22.8 0.5 5.9e-05 22.8 0.5 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF456 PF04306.13 KIR65587.1 - 7.4e-28 97.6 29.1 7.4e-28 97.6 29.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF456) DUF397 PF04149.12 KIR65588.1 - 7.3e-23 80.4 0.6 8e-23 80.3 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KIR65589.1 - 1.2e-11 44.8 0.6 1.2e-11 44.8 0.6 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65589.1 - 1.1e-08 34.9 0.1 2.6e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR65589.1 - 8.3e-05 22.5 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR65589.1 - 0.056 13.4 0.5 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 KIR65589.1 - 0.08 12.7 0.7 0.08 12.7 0.7 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 KIR65589.1 - 0.093 12.7 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 MarR family AA_permease_2 PF13520.6 KIR65593.1 - 4.3e-54 184.0 49.1 5.5e-54 183.6 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIR65593.1 - 5.2e-24 84.7 40.8 6.8e-24 84.3 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease Gln-synt_C PF00120.24 KIR65594.1 - 1.3e-99 333.5 0.0 1.5e-99 333.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KIR65594.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain adh_short_C2 PF13561.6 KIR65595.1 - 5.5e-74 248.7 1.7 6.3e-74 248.4 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR65595.1 - 1.4e-53 181.3 0.1 1.7e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR65595.1 - 1.3e-07 31.7 1.0 3.4e-07 30.4 1.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR65595.1 - 1.7e-06 27.7 0.5 4.3e-06 26.4 0.3 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 KIR65595.1 - 0.00083 19.8 6.0 0.041 14.3 0.2 2.3 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Methyltransf_25 PF13649.6 KIR65595.1 - 0.0084 16.8 0.2 0.015 16.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KIR65595.1 - 0.012 15.1 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIR65595.1 - 0.033 14.1 2.7 0.036 13.9 1.0 2.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIR65595.1 - 0.045 13.7 1.1 0.12 12.4 1.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIR65595.1 - 0.046 14.0 0.4 0.1 12.8 0.4 1.6 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 KIR65595.1 - 0.084 13.5 0.6 0.2 12.4 0.6 1.7 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KIR65595.1 - 0.1 12.0 0.2 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Putative_PNPOx PF01243.20 KIR65596.1 - 5.8e-12 45.6 0.0 1.3e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase SpoIIE PF07228.12 KIR65597.1 - 4.8e-47 160.4 0.8 9.3e-47 159.4 0.8 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c PF02518.26 KIR65597.1 - 8.8e-29 100.3 0.1 2.5e-25 89.2 0.0 2.8 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIR65597.1 - 1.7e-23 82.9 0.0 3.6e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 KIR65597.1 - 8.8e-20 70.9 0.8 2.2e-14 53.5 0.1 3.0 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HisKA PF00512.25 KIR65597.1 - 3.3e-15 55.9 0.1 9.5e-15 54.4 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 KIR65597.1 - 1.1e-05 25.8 2.2 0.058 13.8 0.2 3.7 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 KIR65597.1 - 1.8e-05 25.0 16.1 0.00021 21.6 1.5 5.4 5 1 0 5 5 5 1 GAF domain GAF PF01590.26 KIR65597.1 - 0.014 16.0 0.1 0.09 13.4 0.0 2.4 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.6 KIR65597.1 - 0.11 12.4 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 KIR65597.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.5 4 0 0 4 4 4 0 PAS fold Peptidase_M24 PF00557.24 KIR65598.1 - 3.2e-53 180.5 0.7 3.7e-53 180.3 0.7 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 VIT1 PF01988.19 KIR65599.1 - 4.1e-64 216.4 7.0 4.7e-64 216.2 7.0 1.0 1 0 0 1 1 1 1 VIT family FAM165 PF14981.6 KIR65599.1 - 0.064 13.1 0.9 0.12 12.2 0.9 1.4 1 0 0 1 1 1 0 FAM165 family Lysis_col PF02402.16 KIR65599.1 - 0.48 10.1 2.4 0.81 9.4 1.9 1.7 1 1 0 1 1 1 0 Lysis protein DUF4781 PF16013.5 KIR65599.1 - 0.7 8.6 6.2 0.21 10.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) F420H2_quin_red PF04075.14 KIR65601.1 - 3.3e-30 104.9 0.3 3.8e-30 104.7 0.3 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase FtsX PF02687.21 KIR65602.1 - 7.7e-06 26.3 0.6 7.7e-06 26.3 0.6 4.7 4 1 0 4 4 4 2 FtsX-like permease family PadR PF03551.14 KIR65603.1 - 2.8e-15 56.0 0.1 4.2e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 KIR65603.1 - 1.4e-10 41.7 0.2 2.3e-10 41.0 0.2 1.3 1 0 0 1 1 1 1 Virulence activator alpha C-term AphA_like PF14557.6 KIR65603.1 - 0.058 13.1 0.1 0.1 12.3 0.1 1.4 1 1 0 1 1 1 0 Putative AphA-like transcriptional regulator TrmB PF01978.19 KIR65603.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.8 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4439 PF14530.6 KIR65604.1 - 1.3e-42 145.6 12.0 1.5e-42 145.4 12.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) DUF150 PF02576.17 KIR65605.1 - 6e-23 81.0 0.2 1.2e-22 80.1 0.2 1.5 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 KIR65605.1 - 1.4e-08 34.7 0.1 1.6e-07 31.3 0.1 2.4 1 1 0 1 1 1 1 RimP C-terminal SH3 domain KH_5 PF13184.6 KIR65606.1 - 2.8e-28 97.8 0.1 5.9e-27 93.5 0.0 2.7 3 1 0 3 3 3 1 NusA-like KH domain NusA_N PF08529.11 KIR65606.1 - 2e-19 70.1 0.0 4.5e-09 36.7 0.0 2.3 1 1 1 2 2 2 2 NusA N-terminal domain KH_1 PF00013.29 KIR65606.1 - 0.00096 18.9 0.0 0.71 9.7 0.0 2.5 2 0 0 2 2 2 2 KH domain S1 PF00575.23 KIR65606.1 - 0.0083 16.4 0.2 0.11 12.9 0.3 2.4 2 0 0 2 2 2 1 S1 RNA binding domain IF-2 PF11987.8 KIR65607.1 - 2.5e-35 120.8 0.6 7.1e-35 119.3 0.6 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 KIR65607.1 - 2.6e-34 118.5 6.4 6.6e-34 117.2 2.4 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 KIR65607.1 - 8.4e-21 73.6 0.0 1.6e-13 50.2 0.1 2.7 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 KIR65607.1 - 2.4e-09 37.5 2.1 3.3e-05 24.2 0.2 3.0 3 0 0 3 3 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIR65607.1 - 1.4e-08 34.8 0.1 2.5e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KIR65607.1 - 7.8e-05 22.3 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KIR65607.1 - 0.00059 19.3 0.0 0.0019 17.7 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIR65607.1 - 0.0063 16.0 0.1 0.015 14.8 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KIR65607.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIR65607.1 - 0.017 15.0 0.2 0.1 12.5 0.1 2.2 1 1 1 2 2 2 0 RsgA GTPase Arf PF00025.21 KIR65607.1 - 0.049 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.9 KIR65607.1 - 0.18 11.6 0.2 0.8 9.4 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF503 PF04456.12 KIR65608.1 - 1.7e-26 91.9 0.0 1.8e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF503) DHHA1 PF02272.19 KIR65609.1 - 7.7e-09 36.1 0.2 1.7e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 KIR65609.1 - 4.8e-07 29.9 0.0 9.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 DHH family TruB_N PF01509.18 KIR65612.1 - 1.3e-50 171.7 0.1 2.5e-50 170.7 0.0 1.5 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C PF09142.11 KIR65612.1 - 2.4e-18 65.7 5.4 3.7e-18 65.0 1.8 3.0 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal TruB_C_2 PF16198.5 KIR65612.1 - 6.2e-11 42.3 0.2 1.6e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 KIR65612.1 - 0.067 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain FAD_syn PF06574.12 KIR65613.1 - 1.1e-51 174.9 0.0 1.8e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 KIR65613.1 - 1e-35 122.4 0.0 3.3e-35 120.8 0.0 1.9 3 0 0 3 3 3 1 Riboflavin kinase ATPgrasp_N PF18130.1 KIR65613.1 - 0.012 16.2 0.3 4 8.0 0.0 3.4 3 1 0 3 3 3 0 ATP-grasp N-terminal domain CTP_transf_like PF01467.26 KIR65613.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase-like Ribosomal_S15 PF00312.22 KIR65614.1 - 1.8e-37 127.4 2.2 2.1e-37 127.2 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RNase_PH PF01138.21 KIR65615.1 - 4.5e-38 130.7 0.0 8.1e-20 71.7 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 KIR65615.1 - 4.8e-17 62.2 3.7 4.8e-17 62.2 3.7 1.9 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.29 KIR65615.1 - 2.6e-11 43.2 0.7 2.6e-11 43.2 0.7 1.9 2 0 0 2 2 2 1 KH domain S1 PF00575.23 KIR65615.1 - 8.5e-11 42.1 0.2 1.7e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain RNase_PH_C PF03725.15 KIR65615.1 - 4.6e-09 36.2 0.1 0.004 17.2 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 KH_2 PF07650.17 KIR65615.1 - 0.00038 20.2 0.1 0.00093 19.0 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIR65615.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 2.2 3 0 0 3 3 3 1 KH domain KH_5 PF13184.6 KIR65615.1 - 0.53 10.4 2.3 0.67 10.1 0.3 2.1 2 0 0 2 2 2 0 NusA-like KH domain Peptidase_M16_C PF05193.21 KIR65616.1 - 5.1e-45 153.7 0.0 1.8e-42 145.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIR65616.1 - 5.8e-39 133.4 0.0 8.3e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Phage_Mu_Gp45 PF06890.12 KIR65616.1 - 0.064 13.0 0.2 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein Acetyltransf_1 PF00583.25 KIR65617.1 - 1.7e-10 41.2 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR65617.1 - 1e-06 29.1 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR65617.1 - 4e-05 24.3 0.0 5.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR65617.1 - 6e-05 23.0 0.0 8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR65617.1 - 0.00045 19.9 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65617.1 - 0.0038 17.2 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Peripla_BP_3 PF13377.6 KIR65618.1 - 8e-22 78.3 0.9 8e-22 78.3 0.9 2.5 2 2 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR65618.1 - 5e-19 68.8 0.0 7.7e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR65618.1 - 2.9e-13 49.3 1.2 6e-13 48.4 1.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR65618.1 - 1.5e-06 28.0 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain ZnuA PF01297.17 KIR65618.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic HTH_Tnp_ISL3 PF13542.6 KIR65618.1 - 0.061 12.8 0.4 0.17 11.3 0.4 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 KIR65618.1 - 0.11 12.9 2.8 0.6 10.5 0.3 2.9 1 1 1 2 2 2 0 Helix-turn-helix domain HATPase_c_2 PF13581.6 KIR65618.1 - 0.12 12.4 0.4 0.2 11.6 0.4 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HTH_23 PF13384.6 KIR65618.1 - 0.23 11.3 2.0 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain SBP_bac_8 PF13416.6 KIR65619.1 - 5.2e-34 118.3 9.0 7.4e-34 117.8 9.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR65619.1 - 2.1e-29 103.5 10.8 2.9e-29 103.0 10.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR65619.1 - 0.00016 21.2 0.9 0.16 11.4 0.1 2.6 2 1 1 3 3 3 2 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR65620.1 - 7.9e-21 74.6 14.8 7.9e-21 74.6 14.8 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5472 PF17566.2 KIR65620.1 - 0.94 9.5 3.3 1.9 8.5 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5472) NADH-u_ox-rdase PF10785.9 KIR65620.1 - 1.2 9.8 8.0 7.5 7.3 0.4 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit BPD_transp_1 PF00528.22 KIR65621.1 - 2.8e-18 66.3 10.0 2.8e-18 66.3 10.0 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Acetyltransf_1 PF00583.25 KIR65622.1 - 4.4e-07 30.2 0.0 5.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR65622.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65623.1 - 1.9e-12 47.5 0.0 2.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR65623.1 - 5.9e-07 29.8 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR65623.1 - 1.2e-06 29.3 0.2 1.4e-06 29.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65623.1 - 2.6e-05 24.1 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KIR65623.1 - 0.00049 20.0 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65623.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase HTH_42 PF06224.12 KIR65624.1 - 1.5e-78 264.6 32.9 1.8e-78 264.4 32.9 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF2752 PF10825.8 KIR65625.1 - 8.1e-17 61.0 6.1 8.1e-17 61.0 6.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2752) DEC-1_N PF04625.13 KIR65625.1 - 4.1 6.3 6.9 5 6.0 6.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DHDPS PF00701.22 KIR65626.1 - 2.6e-81 272.5 0.0 2.9e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peripla_BP_6 PF13458.6 KIR65626.1 - 0.015 15.0 0.8 3.7 7.1 0.0 2.9 2 1 1 3 3 3 0 Periplasmic binding protein Amidohydro_2 PF04909.14 KIR65626.1 - 0.016 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase RNase_J_C PF17770.1 KIR65627.1 - 3.5e-13 50.4 0.0 6.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain RMMBL PF07521.12 KIR65627.1 - 1.3e-12 47.4 0.3 4.9e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KIR65627.1 - 6.7e-10 38.8 0.7 1.4e-09 37.8 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIR65627.1 - 5.7e-09 36.3 2.2 5.7e-09 36.3 2.2 2.6 2 2 0 2 2 2 1 Metallo-beta-lactamase superfamily Pro_Al_protease PF02983.14 KIR65628.1 - 1.4e-16 60.3 1.7 1.4e-16 60.3 1.7 2.4 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Trypsin PF00089.26 KIR65628.1 - 1.1e-10 41.8 7.4 2.9e-10 40.4 7.4 1.7 1 1 0 1 1 1 1 Trypsin YbjN PF10722.9 KIR65629.1 - 2.4e-13 50.2 0.2 4.3e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator YbjN PF10722.9 KIR65630.1 - 1.7e-24 86.3 0.1 2e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator FtsK_SpoIIIE PF01580.18 KIR65631.1 - 1.8e-58 197.7 0.5 1.7e-56 191.3 0.5 2.2 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_alpha PF17854.1 KIR65631.1 - 2.5e-26 91.8 0.0 4.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 KIR65631.1 - 3.5e-23 81.2 0.0 7.2e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_4TM PF13491.6 KIR65631.1 - 2.8e-15 56.5 3.3 2.8e-15 56.5 3.3 1.8 1 1 1 2 2 2 1 4TM region of DNA translocase FtsK/SpoIIIE AAA_10 PF12846.7 KIR65631.1 - 0.00045 19.2 0.0 0.0048 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain TrwB_AAD_bind PF10412.9 KIR65631.1 - 0.0014 17.6 0.0 0.0041 16.1 0.0 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 KIR65631.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 KIR65631.1 - 0.009 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIR65631.1 - 0.026 14.6 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KIR65631.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIR65631.1 - 0.045 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF853 PF05872.12 KIR65631.1 - 0.077 11.6 0.1 3.9 5.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Adeno_IVa2 PF02456.15 KIR65631.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein TniB PF05621.11 KIR65631.1 - 0.13 11.6 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KIR65631.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF3377 PF11857.8 KIR65631.1 - 9.1 6.3 6.5 19 5.2 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Rick_17kDa_Anti PF05433.15 KIR65632.1 - 0.068 13.0 8.2 0.11 12.4 8.2 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain CPBP PF02517.16 KIR65632.1 - 0.27 11.6 3.1 0.4 11.1 3.1 1.4 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease RseC_MucC PF04246.12 KIR65632.1 - 2.5 8.0 8.4 3.1 7.7 8.4 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC VIT1 PF01988.19 KIR65632.1 - 3.8 7.3 11.2 4.4 7.1 11.2 1.1 1 0 0 1 1 1 0 VIT family Phage_holin_5_2 PF16079.5 KIR65632.1 - 4 7.8 9.3 1.2 9.5 4.3 2.1 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF4231 PF14015.6 KIR65632.1 - 9.8 6.7 7.1 30 5.1 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Multi_Drug_Res PF00893.19 KIR65633.1 - 1.4e-23 83.3 7.6 1.8e-23 83.0 7.6 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein DUF378 PF04070.12 KIR65633.1 - 0.037 13.9 1.7 0.037 13.9 1.7 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF378) EamA PF00892.20 KIR65633.1 - 0.34 11.1 10.7 0.46 10.6 10.7 1.3 1 1 0 1 1 1 0 EamA-like transporter family DUF2721 PF11026.8 KIR65633.1 - 0.92 9.4 8.3 0.07 13.0 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) OCD_Mu_crystall PF02423.15 KIR65634.1 - 1.2e-43 149.3 3.8 1.5e-43 148.9 3.8 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KIR65634.1 - 8.4e-06 25.9 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIR65634.1 - 0.00078 20.0 0.2 0.0019 18.7 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UPF0004 PF00919.20 KIR65635.1 - 2e-29 101.5 0.2 3.2e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KIR65635.1 - 5.9e-21 75.6 0.0 1.2e-20 74.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily TRAM_2 PF18693.1 KIR65635.1 - 7.1e-14 51.7 1.3 2.5e-13 50.0 0.5 2.3 3 0 0 3 3 3 1 TRAM domain TraT PF05818.12 KIR65635.1 - 0.055 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein CLP1_P PF16575.5 KIR65635.1 - 0.086 12.6 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CDP-OH_P_transf PF01066.21 KIR65636.1 - 2.8e-14 53.6 1.4 2.8e-14 53.6 1.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2700 PF10912.8 KIR65636.1 - 0.016 15.3 0.4 0.035 14.1 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2700) SseC PF04888.12 KIR65636.1 - 3.3 7.2 4.7 4.4 6.8 4.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family HXXEE PF13787.6 KIR65636.1 - 5 8.0 8.7 3 8.7 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif HTH_31 PF13560.6 KIR65637.1 - 3.8e-12 46.4 3.2 8e-12 45.3 3.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65637.1 - 7.8e-11 41.9 0.2 1.1e-10 41.4 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR65637.1 - 1e-06 28.6 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR65637.1 - 0.00015 21.6 0.4 0.0003 20.6 0.4 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR65637.1 - 0.00038 20.8 0.0 0.00055 20.3 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain PspA_IM30 PF04012.12 KIR65638.1 - 6.7e-45 153.4 30.1 8.6e-45 153.0 30.1 1.1 1 0 0 1 1 1 1 PspA/IM30 family DUF883 PF05957.13 KIR65638.1 - 0.017 15.7 0.3 0.017 15.7 0.3 4.2 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) Jnk-SapK_ap_N PF09744.9 KIR65638.1 - 9.3 6.4 19.9 3.1 8.0 4.4 2.4 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 SLATT_1 PF18181.1 KIR65639.1 - 0.004 17.1 6.5 0.014 15.3 2.0 2.9 3 0 0 3 3 3 2 SMODS and SLOG-associating 2TM effector domain 1 zf-FPG_IleRS PF06827.14 KIR65640.1 - 3.7e-10 39.5 4.6 7.3e-10 38.5 4.6 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS H2TH PF06831.14 KIR65640.1 - 1.8e-09 37.4 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 KIR65640.1 - 6.7e-06 26.7 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Phageshock_PspD PF09584.10 KIR65640.1 - 0.0015 18.5 0.5 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 Phage shock protein PspD (Phageshock_PspD) DZR PF12773.7 KIR65640.1 - 0.077 13.0 0.7 0.13 12.3 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon SAM_adeno_trans PF01887.16 KIR65641.1 - 2.8e-78 262.6 0.1 3.2e-78 262.4 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase Ser_hydrolase PF06821.13 KIR65642.1 - 2.3e-44 151.2 0.1 2.7e-44 151.1 0.1 1.0 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 KIR65642.1 - 1.2e-05 25.1 0.0 0.078 12.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR65642.1 - 0.00024 21.8 18.0 0.00058 20.5 18.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR65642.1 - 0.0056 16.0 0.0 0.0092 15.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR65642.1 - 0.014 15.5 0.1 2.4 8.3 0.0 2.3 2 1 0 2 2 2 0 TAP-like protein HTH_31 PF13560.6 KIR65643.1 - 2.7e-13 50.0 0.8 2.7e-13 50.0 0.8 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR65643.1 - 5.1e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_12 PF13424.6 KIR65643.1 - 0.035 14.4 0.6 0.035 14.4 0.6 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIR65643.1 - 1.3 9.8 0.1 1.3 9.8 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_31 PF13560.6 KIR65644.1 - 5.2e-11 42.7 3.5 5.2e-11 42.7 3.5 4.5 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR65644.1 - 6.8e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65644.1 - 0.00016 21.6 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix KorB PF08535.10 KIR65644.1 - 0.017 15.1 0.0 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 KorB domain HTH_23 PF13384.6 KIR65644.1 - 0.018 14.8 0.3 0.077 12.8 0.2 2.2 1 1 0 1 1 1 0 Homeodomain-like domain TPR_14 PF13428.6 KIR65644.1 - 0.023 15.5 2.8 0.023 15.5 2.8 7.2 4 2 4 8 8 8 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 KIR65644.1 - 0.025 14.1 0.0 0.52 9.9 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 TPR_12 PF13424.6 KIR65644.1 - 0.057 13.7 0.9 0.057 13.7 0.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_38 PF13936.6 KIR65644.1 - 0.071 12.9 0.1 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4081 PF13312.6 KIR65645.1 - 0.093 12.9 0.1 0.13 12.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4081) FAD_binding_3 PF01494.19 KIR65646.1 - 7.3e-95 318.2 0.0 8.7e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR65646.1 - 8.9e-07 28.8 5.0 0.0019 17.9 0.2 2.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR65646.1 - 2.7e-06 26.4 0.1 0.00011 21.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KIR65646.1 - 1.4e-05 24.5 0.1 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR65646.1 - 6.1e-05 23.5 0.1 0.0048 17.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR65646.1 - 0.00029 21.0 0.1 0.0013 18.9 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR65646.1 - 0.0003 20.0 0.4 0.0021 17.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KIR65646.1 - 0.0012 17.8 0.0 0.52 9.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 KIR65646.1 - 0.014 14.5 0.1 0.025 13.7 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIR65646.1 - 0.017 14.4 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2384 PF09722.10 KIR65646.1 - 0.046 13.8 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Ricin_B_lectin PF00652.22 KIR65647.1 - 1.9e-29 102.5 14.4 2.8e-29 102.0 13.5 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR65647.1 - 1.9e-25 89.4 28.8 5.8e-12 46.2 4.5 4.5 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Peptidase_S9 PF00326.21 KIR65647.1 - 0.0013 18.2 0.9 0.0013 18.2 0.9 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family ET PF01684.16 KIR65647.1 - 1.2 9.5 5.8 33 4.9 0.4 3.3 1 1 2 3 3 3 0 ET module DUF4139 PF13598.6 KIR65649.1 - 2.4e-55 187.5 0.0 3.2e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIR65649.1 - 3.8e-23 81.8 11.5 5.9e-23 81.2 0.2 4.2 4 1 1 5 5 5 1 N-terminal domain of unknown function (DUF4140) DUF11 PF01345.18 KIR65649.1 - 0.00047 20.4 1.6 0.0022 18.2 0.2 2.8 1 1 1 2 2 2 1 Domain of unknown function DUF11 Proton_antipo_M PF00361.20 KIR65650.1 - 4e-58 196.9 17.1 4e-58 196.9 17.1 2.4 3 0 0 3 3 3 1 Proton-conducting membrane transporter MnhB PF04039.13 KIR65650.1 - 5.9e-27 94.4 18.0 5.9e-27 94.4 18.0 7.8 2 1 7 10 10 10 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 KIR65650.1 - 2e-20 72.7 10.1 2e-20 72.7 10.1 5.5 6 2 0 6 6 6 1 Domain of unknown function (DUF4040) Proton_antipo_N PF00662.20 KIR65650.1 - 3.2e-07 30.3 2.3 3.8e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q3 PF00499.20 KIR65650.1 - 0.00013 21.7 0.0 0.00013 21.7 0.0 4.3 2 2 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Oxidored_q2 PF00420.24 KIR65651.1 - 6.7e-24 83.5 1.2 8.6e-24 83.2 1.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ost4 PF10215.9 KIR65651.1 - 0.067 13.0 1.6 0.067 13.0 1.6 2.2 2 0 0 2 2 2 0 Oligosaccaryltransferase Proton_antipo_M PF00361.20 KIR65652.1 - 1e-61 208.7 18.4 1e-61 208.7 18.4 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 KIR65652.1 - 0.00039 20.4 0.3 0.00039 20.4 0.3 2.9 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Pox_A9 PF04835.12 KIR65652.1 - 1.9 8.7 6.8 7.1 6.9 0.1 3.5 2 1 1 3 3 3 0 A9 protein conserved region MrpF_PhaF PF04066.13 KIR65653.1 - 2.3e-11 43.9 5.9 2.3e-11 43.9 5.9 2.1 1 1 1 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF2567 PF10821.8 KIR65653.1 - 0.63 10.1 8.7 0.068 13.2 3.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2567) DUF5305 PF17231.2 KIR65653.1 - 1.5 8.1 4.1 0.72 9.2 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF21 PF01595.20 KIR65654.1 - 9.1e-40 136.2 3.0 1.3e-39 135.7 3.0 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIR65654.1 - 1.7e-09 38.0 0.1 0.00056 20.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain MIase PF02426.16 KIR65654.1 - 0.038 14.1 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Muconolactone delta-isomerase Spo0M PF07070.11 KIR65655.1 - 3e-40 138.0 0.0 3.9e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 SpoOM protein LysE PF01810.18 KIR65656.1 - 2.2e-47 161.1 9.7 2.6e-47 160.8 9.7 1.1 1 0 0 1 1 1 1 LysE type translocator DUF3792 PF12670.7 KIR65656.1 - 7.1 6.8 13.2 0.53 10.5 6.1 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3792) Pyridox_ox_2 PF12900.7 KIR65657.1 - 8.4e-44 149.0 2.1 2.4e-43 147.5 0.4 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Acetyltransf_3 PF13302.7 KIR65657.1 - 7.5e-22 78.5 0.1 1.2e-21 77.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65657.1 - 0.0038 17.4 0.0 0.0068 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR65657.1 - 0.005 16.5 0.2 0.014 15.0 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FMN_bind_2 PF04299.12 KIR65657.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative FMN-binding domain Aminotran_1_2 PF00155.21 KIR65658.1 - 1.1e-16 61.0 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 KIR65658.1 - 8.1e-14 51.0 0.6 6.6e-13 48.1 0.4 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 KIR65658.1 - 0.00019 21.4 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KIR65658.1 - 0.00079 19.3 0.4 0.00079 19.3 0.4 4.0 4 0 0 4 4 4 1 MarR family HTH_28 PF13518.6 KIR65658.1 - 0.0015 18.6 2.5 0.0026 17.9 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR65658.1 - 0.003 17.4 0.1 0.013 15.3 0.1 2.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 KIR65658.1 - 0.0032 17.2 0.2 0.02 14.7 0.2 2.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Aminotran_MocR PF12897.7 KIR65658.1 - 0.0041 16.0 0.0 0.0078 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_24 PF13412.6 KIR65658.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 KIR65658.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 KIR65658.1 - 0.0082 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 KIR65658.1 - 0.0094 16.0 0.1 0.04 13.9 0.1 2.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIR65658.1 - 0.019 14.8 2.2 0.058 13.2 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KIR65658.1 - 0.03 13.7 0.3 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 KIR65658.1 - 0.071 13.5 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator E3_binding PF02817.17 KIR65658.1 - 0.095 13.1 2.2 0.11 12.8 0.1 2.3 2 0 0 2 2 2 0 e3 binding domain HTH_11 PF08279.12 KIR65658.1 - 0.098 12.6 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 HTH domain TrmB PF01978.19 KIR65658.1 - 0.12 12.3 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 KIR65658.1 - 0.16 11.8 0.0 0.53 10.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain UDG PF03167.19 KIR65659.1 - 6.1e-34 117.3 0.0 7.6e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MFS_1 PF07690.16 KIR65660.1 - 3.4e-27 95.3 54.4 1.6e-17 63.5 17.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR65660.1 - 1.8e-11 43.6 26.1 1.4e-07 30.8 7.0 2.8 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KIR65660.1 - 3.2e-05 22.7 16.0 0.017 13.7 3.2 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein Bclt PF15318.6 KIR65660.1 - 0.99 9.2 3.9 1.6 8.5 3.9 1.3 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis Nuc_H_symport PF03825.16 KIR65660.1 - 3 6.7 9.0 0.085 11.8 1.9 2.0 2 1 1 3 3 3 0 Nucleoside H+ symporter DUF3046 PF11248.8 KIR65661.1 - 3e-25 88.3 0.1 3.3e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3046) RecA PF00154.21 KIR65662.1 - 1.5e-143 477.0 2.4 1.8e-143 476.7 2.4 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KIR65662.1 - 1.4e-09 37.7 0.3 5.9e-08 32.3 0.3 2.6 1 1 0 1 1 1 1 KaiC Rad51 PF08423.11 KIR65662.1 - 5.8e-09 35.6 0.1 1.9e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 Rad51 ATPase_2 PF01637.18 KIR65662.1 - 0.00027 20.9 0.0 0.00061 19.8 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KIR65662.1 - 0.0009 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIR65662.1 - 0.002 17.7 0.8 0.048 13.2 0.8 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIR65662.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIR65662.1 - 0.014 15.8 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain CobU PF02283.16 KIR65662.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RecX PF02631.16 KIR65663.1 - 1.9e-26 92.9 0.3 9e-25 87.5 0.1 2.0 1 1 1 2 2 2 2 RecX family LpxI_N PF17930.1 KIR65663.1 - 0.071 13.0 0.1 0.68 9.8 0.0 2.0 1 1 1 2 2 2 0 LpxI N-terminal domain DUF3552 PF12072.8 KIR65664.1 - 7.8e-20 71.2 48.6 7.8e-20 71.2 48.6 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3552) HD PF01966.22 KIR65664.1 - 3.3e-16 59.6 2.5 3.3e-16 59.6 2.5 2.8 2 1 0 2 2 2 1 HD domain KH_1 PF00013.29 KIR65664.1 - 6.7e-06 25.9 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIR65664.1 - 0.00045 20.0 1.7 0.0011 18.7 0.2 2.5 2 0 0 2 2 2 1 KH domain DUF3776 PF12618.8 KIR65664.1 - 0.49 11.0 6.7 0.13 12.9 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3776) BPD_transp_1 PF00528.22 KIR65665.1 - 8.4e-17 61.5 16.1 1.5e-16 60.7 16.1 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 KIR65666.1 - 1.6e-50 171.6 1.3 2.1e-50 171.3 1.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 KIR65666.1 - 0.03 14.2 0.5 5.1 7.0 0.0 2.4 2 1 0 2 2 2 0 NMT1/THI5 like Phosphonate-bd PF12974.7 KIR65666.1 - 0.034 13.8 0.1 0.098 12.2 0.0 1.7 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Lig_chan-Glu_bd PF10613.9 KIR65666.1 - 0.083 13.1 0.0 0.23 11.7 0.0 1.9 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site ABC_tran PF00005.27 KIR65667.1 - 1.6e-34 119.4 0.0 2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65667.1 - 6.7e-12 45.8 0.0 1e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR65667.1 - 7.3e-09 35.4 0.4 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR65667.1 - 4e-05 24.1 0.4 7.3e-05 23.2 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR65667.1 - 0.00011 22.4 0.0 0.00027 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR65667.1 - 0.00012 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KIR65667.1 - 0.00018 20.4 0.4 0.38 9.5 0.1 2.6 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_18 PF13238.6 KIR65667.1 - 0.00053 20.6 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR65667.1 - 0.0017 18.1 0.1 0.0032 17.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR65667.1 - 0.003 17.5 0.1 0.0064 16.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 KIR65667.1 - 0.0048 17.1 0.1 0.013 15.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR65667.1 - 0.0052 17.3 0.0 0.0084 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR65667.1 - 0.0093 16.2 0.3 0.03 14.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KIR65667.1 - 0.0097 15.7 0.1 0.029 14.2 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_13 PF13166.6 KIR65667.1 - 0.012 14.3 0.0 0.88 8.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain CobU PF02283.16 KIR65667.1 - 0.028 14.0 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PduV-EutP PF10662.9 KIR65667.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 KIR65667.1 - 0.038 13.6 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIR65667.1 - 0.04 13.6 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 KIR65667.1 - 0.042 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KIR65667.1 - 0.044 14.2 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIR65667.1 - 0.047 13.8 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KIR65667.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 KIR65667.1 - 0.063 13.0 0.0 0.27 10.9 0.0 1.8 1 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 KIR65667.1 - 0.064 13.5 0.3 0.57 10.5 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KIR65667.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR65667.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KIR65667.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIR65667.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIR65667.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KIR65667.1 - 0.16 12.0 0.0 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 KIR65667.1 - 0.32 9.8 0.5 0.6 8.9 0.1 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AIRS PF00586.24 KIR65668.1 - 1.6e-20 73.5 0.7 5.4e-20 71.9 0.1 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 KIR65668.1 - 1.1e-13 51.6 0.3 2.1e-13 50.7 0.3 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain DUF2277 PF10041.9 KIR65670.1 - 8.4e-27 93.3 0.6 9e-27 93.2 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) Pec_lyase_C PF00544.19 KIR65671.1 - 1e-39 136.3 11.5 7.8e-39 133.4 11.5 2.0 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIR65671.1 - 4.1e-12 46.2 19.4 4.3e-10 39.7 12.9 2.1 1 1 1 2 2 2 2 Right handed beta helix region Glyco_hydro_49 PF03718.13 KIR65671.1 - 0.029 14.4 1.0 0.046 13.7 0.1 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 Cellulase PF00150.18 KIR65672.1 - 8.6e-59 199.3 2.7 1.1e-58 198.9 2.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_2 PF00553.19 KIR65672.1 - 1.5e-23 83.0 14.9 1.5e-23 83.0 14.9 2.3 2 0 0 2 2 2 1 Cellulose binding domain Glyco_hydro_42 PF02449.15 KIR65672.1 - 0.00088 18.7 0.1 0.56 9.5 0.0 2.7 2 1 1 3 3 3 2 Beta-galactosidase DUF11 PF01345.18 KIR65672.1 - 0.0011 19.2 4.3 0.0034 17.7 4.3 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF11 DUF349 PF03993.12 KIR65673.1 - 5.3e-55 183.6 53.0 1.4e-23 83.0 7.5 4.5 4 1 0 4 4 4 3 Domain of Unknown Function (DUF349) DUF1090 PF06476.12 KIR65673.1 - 0.0028 17.8 6.4 0.0028 17.8 6.4 4.3 2 1 1 4 4 4 3 Protein of unknown function (DUF1090) DUF4363 PF14276.6 KIR65673.1 - 0.29 11.3 16.2 0.59 10.3 1.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4363) LigB PF02900.18 KIR65674.1 - 0.00032 19.8 0.0 0.039 13.0 0.0 2.1 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase IPPT PF01715.17 KIR65675.1 - 5.1e-75 252.2 0.0 6e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KIR65675.1 - 1.7e-06 27.6 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 KIR65675.1 - 0.00064 19.9 0.1 0.0015 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KIR65675.1 - 0.0053 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_25 PF13481.6 KIR65675.1 - 0.037 13.6 0.5 0.11 12.0 0.5 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIR65675.1 - 0.068 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KIR65675.1 - 0.1 11.7 0.2 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain PGM_PMM_IV PF00408.20 KIR65675.1 - 0.13 12.4 0.7 2.8 8.2 0.2 2.8 2 1 1 3 3 3 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain AAA_16 PF13191.6 KIR65675.1 - 0.15 12.4 4.1 0.5 10.7 4.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KIR65675.1 - 0.2 12.1 0.1 0.37 11.3 0.1 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KIR65675.1 - 0.21 12.1 0.0 0.32 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DAP_epimerase PF01678.19 KIR65676.1 - 5.5e-53 178.3 0.1 4.6e-32 110.7 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase Pro_racemase PF05544.11 KIR65676.1 - 0.0017 17.4 0.1 0.067 12.2 0.0 2.1 2 0 0 2 2 2 2 Proline racemase Flavi_propep PF01570.17 KIR65676.1 - 0.034 14.1 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide malic PF00390.19 KIR65677.1 - 2.2e-30 105.8 0.0 4e-28 98.5 0.0 2.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KIR65677.1 - 8.9e-23 80.9 2.5 8.9e-23 80.9 2.5 2.9 3 1 0 3 3 3 1 Malic enzyme, NAD binding domain ThiF PF00899.21 KIR65677.1 - 0.00031 20.2 0.5 0.00065 19.1 0.5 1.5 1 0 0 1 1 1 1 ThiF family ELFV_dehydrog PF00208.21 KIR65677.1 - 0.0048 16.7 0.3 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 KIR65677.1 - 0.011 15.7 0.2 0.037 14.1 0.1 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ACT_4 PF13291.6 KIR65677.1 - 0.013 16.0 0.1 0.19 12.4 0.0 3.0 3 0 0 3 3 3 0 ACT domain AlaDh_PNT_C PF01262.21 KIR65677.1 - 0.016 14.5 0.3 0.016 14.5 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIR65677.1 - 0.029 13.7 0.1 0.072 12.4 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NapD PF03927.13 KIR65677.1 - 0.13 12.3 0.1 11 6.1 0.0 2.9 2 0 0 2 2 2 0 NapD protein GTP-bdg_N PF13167.6 KIR65678.1 - 5.3e-33 113.6 0.0 1.5e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 KIR65678.1 - 7.6e-30 103.3 9.0 7.6e-30 103.3 9.0 2.8 2 1 1 3 3 3 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 KIR65678.1 - 2.2e-20 72.8 0.0 5.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIR65678.1 - 4.4e-07 29.6 0.0 8.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIR65678.1 - 1.6e-05 24.9 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KIR65678.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain cobW PF02492.19 KIR65678.1 - 0.00016 21.4 0.6 0.037 13.6 0.0 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KIR65678.1 - 0.00048 20.2 0.0 0.0016 18.5 0.0 1.8 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 KIR65678.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KIR65678.1 - 0.0015 18.1 0.1 0.2 11.2 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIR65678.1 - 0.0063 16.9 0.8 0.023 15.1 0.2 2.1 2 0 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 KIR65679.1 - 0.0017 18.3 0.4 1.2 9.2 0.1 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Phytase-like PF13449.6 KIR65679.1 - 0.017 15.1 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 Esterase-like activity of phytase Pollen_allerg_2 PF01620.16 KIR65679.1 - 3.4 7.9 5.6 0.5 10.6 1.4 1.8 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) LexA_DNA_bind PF01726.16 KIR65680.1 - 5e-27 93.5 0.0 7.8e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 KIR65680.1 - 1.8e-15 56.6 0.0 2.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like MarR_2 PF12802.7 KIR65680.1 - 8.1e-06 25.6 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KIR65680.1 - 5e-05 23.1 0.0 9.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR65680.1 - 0.00051 19.5 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 KIR65680.1 - 0.0065 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KIR65680.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR65680.1 - 0.031 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain FaeA PF04703.12 KIR65680.1 - 0.037 14.4 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 FaeA-like protein HTH_27 PF13463.6 KIR65680.1 - 0.051 14.1 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 KIR65680.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DsrC PF04358.13 KIR65680.1 - 0.18 12.4 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 DsrC like protein ATP-cone PF03477.16 KIR65681.1 - 3.2e-14 53.3 0.0 4.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 ATP cone domain TF_Zn_Ribbon PF08271.12 KIR65681.1 - 0.0024 17.3 2.1 0.92 9.1 0.1 2.6 3 0 0 3 3 3 2 TFIIB zinc-binding Cys_rich_CPXG PF14255.6 KIR65681.1 - 0.017 15.0 0.5 0.83 9.6 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C2H2_4 PF13894.6 KIR65681.1 - 0.033 15.0 1.0 0.93 10.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KIR65681.1 - 0.07 12.6 1.9 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 KIR65681.1 - 0.071 13.0 1.4 0.18 11.7 1.4 1.7 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.6 KIR65681.1 - 0.11 13.2 1.6 5.2 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_4 PF13717.6 KIR65681.1 - 0.26 11.2 1.8 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KIR65681.1 - 0.47 10.8 3.1 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2 PF00096.26 KIR65681.1 - 0.52 10.9 4.1 0.9 10.1 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.7 KIR65681.1 - 0.62 10.1 5.5 1.6 8.8 5.6 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 KIR65681.1 - 1 9.9 4.0 1.6 9.3 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zinc_ribbon_2 PF13240.6 KIR65681.1 - 1.1 9.1 4.7 13 5.7 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KIR65681.1 - 5.7 7.1 5.7 0.83 9.7 0.2 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2332 PF10094.9 KIR65682.1 - 3.2e-82 276.7 13.7 2.3e-80 270.6 13.7 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2332) Abhydrolase_1 PF00561.20 KIR65683.1 - 6.7e-10 39.0 0.0 8.4e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR65683.1 - 1.7e-07 30.8 0.2 3.5e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 KIR65684.1 - 9.4e-19 67.9 0.0 2.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65684.1 - 7.4e-16 58.6 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR65684.1 - 4.7e-14 52.5 0.0 5.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65684.1 - 2.2e-07 31.5 0.0 6.1e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65684.1 - 6.5e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR65684.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.7 KIR65684.1 - 0.12 12.3 0.1 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase TehB PF03848.14 KIR65684.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 KIR65684.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF5522 PF17653.1 KIR65685.1 - 1.3e-19 69.9 0.3 1.6e-19 69.6 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5522) ABA_WDS PF02496.16 KIR65685.1 - 0.0091 16.5 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 ABA/WDS induced protein DUF3558 PF12079.8 KIR65686.1 - 0.045 13.8 0.8 0.048 13.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Fe_dep_repr_C PF02742.15 KIR65687.1 - 7.4e-26 90.0 0.1 2.2e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 KIR65687.1 - 1.5e-19 69.9 0.1 3.4e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain FeoA PF04023.14 KIR65687.1 - 6.6e-10 39.1 2.8 7.6e-10 38.9 0.5 2.1 2 1 0 2 2 2 1 FeoA domain MarR_2 PF12802.7 KIR65687.1 - 1.1e-05 25.2 0.4 4.4e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 MarR family RepB PF07506.11 KIR65687.1 - 6.5e-05 23.1 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 RepB plasmid partitioning protein HTH_24 PF13412.6 KIR65687.1 - 0.0013 18.2 0.4 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 KIR65687.1 - 0.0014 19.1 0.6 0.019 15.5 0.1 2.8 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 KIR65687.1 - 0.0015 18.4 0.6 0.006 16.5 0.1 2.2 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HemN_C PF06969.16 KIR65687.1 - 0.0019 18.3 0.1 0.0065 16.5 0.1 2.0 1 0 0 1 1 1 1 HemN C-terminal domain HTH_20 PF12840.7 KIR65687.1 - 0.0054 16.8 0.7 0.034 14.2 0.1 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain MarR PF01047.22 KIR65687.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 MarR family LexA_DNA_bind PF01726.16 KIR65687.1 - 0.032 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain HTH_1 PF00126.27 KIR65687.1 - 0.049 13.6 0.3 0.15 12.0 0.3 1.9 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family ABATE PF07336.11 KIR65687.1 - 0.98 10.1 7.0 0.12 13.0 1.0 2.3 2 1 1 3 3 3 0 Putative stress-induced transcription regulator Rhodanese PF00581.20 KIR65688.1 - 6.7e-29 100.5 0.0 6.3e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Hist_deacetyl PF00850.19 KIR65689.1 - 1.8e-72 244.4 0.0 2.7e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-grasp_5 PF13549.6 KIR65690.1 - 2.6e-55 187.3 0.1 4.2e-55 186.6 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KIR65690.1 - 1.5e-39 134.9 5.4 6.1e-39 133.0 0.0 3.5 3 2 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIR65690.1 - 1.5e-20 73.9 1.7 1.5e-20 73.9 1.7 3.1 4 0 0 4 4 4 1 CoA binding domain Acetyltransf_1 PF00583.25 KIR65690.1 - 4.7e-12 46.2 1.5 1e-11 45.1 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KIR65690.1 - 6.5e-08 33.4 0.0 1.7e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 KIR65690.1 - 1.9e-07 31.7 1.1 5.4e-06 27.0 1.1 2.7 2 0 0 2 2 2 1 CoA binding domain Acetyltransf_4 PF13420.7 KIR65690.1 - 2.3e-06 27.9 0.0 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65690.1 - 1.4e-05 25.4 0.3 0.00021 21.7 0.1 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR65690.1 - 0.00011 22.2 0.7 0.00043 20.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65690.1 - 0.00021 21.2 0.2 0.003 17.5 0.0 2.7 2 1 1 3 3 3 1 FR47-like protein Acetyltransf_CG PF14542.6 KIR65690.1 - 0.028 14.5 1.8 0.042 14.0 0.1 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Sigma70_r2 PF04542.14 KIR65691.1 - 2.9e-23 81.4 0.4 7.2e-23 80.1 0.3 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 KIR65691.1 - 1.2e-19 70.2 0.3 1.4e-17 63.5 0.1 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 KIR65691.1 - 6.4e-18 64.0 8.4 2.5e-17 62.1 2.8 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 KIR65691.1 - 7.9e-15 54.6 0.4 2.1e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 HTH_10 PF04967.12 KIR65691.1 - 0.037 13.8 0.0 8.2 6.3 0.0 2.9 3 0 0 3 3 3 0 HTH DNA binding domain HTH_28 PF13518.6 KIR65691.1 - 0.065 13.4 0.3 0.8 9.9 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Tyr_Deacylase PF02580.16 KIR65692.1 - 8.1e-49 165.9 0.1 9e-49 165.7 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase HhH-GPD PF00730.25 KIR65693.1 - 4e-11 43.3 0.0 6.3e-11 42.7 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein LtrA PF06772.11 KIR65694.1 - 3.3e-90 302.9 43.0 3.7e-90 302.7 43.0 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2644 PF10841.8 KIR65694.1 - 0.029 14.6 3.6 0.84 9.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) DUF1430 PF07242.11 KIR65694.1 - 0.18 12.0 2.9 13 6.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF1129 PF06570.11 KIR65694.1 - 0.38 10.2 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1211 PF06736.11 KIR65694.1 - 0.75 10.3 12.9 1.1 9.8 1.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) Ycf9 PF01737.17 KIR65694.1 - 9.6 6.2 12.7 5.9 6.8 0.8 3.7 3 0 0 3 3 3 0 YCF9 DUF3099 PF11298.8 KIR65695.1 - 1.6e-25 89.1 0.6 2.1e-25 88.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) LtrA PF06772.11 KIR65695.1 - 0.023 13.9 0.3 0.028 13.6 0.3 1.0 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) FA_desaturase PF00487.24 KIR65695.1 - 0.086 12.7 0.1 0.094 12.5 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Adipogenin PF15202.6 KIR65695.1 - 0.09 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Adipogenin PfkB PF00294.24 KIR65696.1 - 6.7e-49 166.8 8.6 8.1e-49 166.5 8.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Nitro_FeMo-Co PF02579.17 KIR65696.1 - 0.37 11.1 1.7 18 5.8 0.1 3.2 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor Indigoidine_A PF04227.12 KIR65697.1 - 4.7e-113 377.4 2.8 5.3e-113 377.2 2.8 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein DUF3039 PF11238.8 KIR65698.1 - 2.1e-26 91.4 0.4 2.5e-26 91.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) UPF0126 PF03458.13 KIR65699.1 - 1.3e-41 140.3 31.8 1.2e-21 76.4 7.0 2.6 3 0 0 3 3 3 2 UPF0126 domain ResIII PF04851.15 KIR65700.1 - 3.2e-12 46.8 0.0 6.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIR65700.1 - 2.8e-06 27.2 0.0 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KIR65700.1 - 8.5e-06 25.6 1.1 8.5e-06 25.6 1.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIR65700.1 - 0.00032 21.0 0.3 0.00091 19.6 0.3 1.8 1 0 0 1 1 1 1 AAA domain Helicase_C PF00271.31 KIR65700.1 - 0.00042 20.6 0.0 0.00081 19.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIR65700.1 - 0.001 19.4 0.2 0.014 15.6 0.1 2.8 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 KIR65700.1 - 0.012 16.0 0.0 0.075 13.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KIR65700.1 - 0.012 15.2 0.6 0.012 15.2 0.6 3.8 4 1 0 4 4 4 0 AAA domain PhoH PF02562.16 KIR65700.1 - 0.014 14.8 0.2 0.031 13.7 0.2 1.5 1 1 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KIR65700.1 - 0.096 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 KIR65700.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KIR65700.1 - 0.17 11.9 0.0 0.93 9.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Pentapeptide_3 PF13576.6 KIR65700.1 - 0.21 11.7 0.8 3.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Inositol_P PF00459.25 KIR65701.1 - 5.4e-54 183.5 0.6 6.4e-54 183.3 0.6 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family LytR_C PF13399.6 KIR65702.1 - 3.5e-13 50.3 0.3 6.2e-13 49.5 0.3 1.4 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator FeoB_associated PF12669.7 KIR65702.1 - 0.031 14.7 0.6 0.056 13.9 0.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4193 PF13834.6 KIR65703.1 - 8.4e-41 138.4 2.0 9.3e-41 138.3 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) DUF3093 PF11292.8 KIR65704.1 - 5.9e-45 153.0 9.2 6.9e-45 152.7 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) dUTPase PF00692.19 KIR65705.1 - 1.1e-29 102.7 0.0 1.3e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF3710 PF12502.8 KIR65706.1 - 9.1e-61 204.6 2.2 1.1e-60 204.3 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) tRNA_anti-codon PF01336.25 KIR65707.1 - 0.0024 17.8 0.1 0.0082 16.1 0.1 1.9 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain TrkA_N PF02254.18 KIR65708.1 - 1.6e-25 89.6 0.2 2.6e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 KIR65708.1 - 5.2e-15 55.0 1.7 2.3e-14 53.0 0.2 2.5 2 0 0 2 2 2 1 TrkA-C domain NAD_binding_10 PF13460.6 KIR65708.1 - 1.8e-08 34.5 0.4 3.7e-08 33.5 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KIR65708.1 - 4.5e-07 30.4 0.1 9.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KIR65708.1 - 3.9e-06 27.2 0.5 7.9e-06 26.3 0.3 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIR65708.1 - 0.0001 21.7 0.1 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIR65708.1 - 0.0001 22.3 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIR65708.1 - 0.00021 21.8 0.0 0.00053 20.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIR65708.1 - 0.00041 20.0 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KIR65708.1 - 0.00053 20.2 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KIR65708.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 KIR65708.1 - 0.0012 19.3 0.1 0.0048 17.4 0.0 1.9 1 1 1 2 2 2 1 XdhC Rossmann domain Epimerase PF01370.21 KIR65708.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIR65708.1 - 0.0024 18.0 0.1 0.0053 16.8 0.1 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DFP PF04127.15 KIR65708.1 - 0.0079 16.0 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein FAD_binding_3 PF01494.19 KIR65708.1 - 0.009 15.3 0.1 0.015 14.6 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain AdoHcyase_NAD PF00670.21 KIR65708.1 - 0.028 14.5 0.2 0.049 13.7 0.2 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NmrA PF05368.13 KIR65708.1 - 0.035 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family IlvN PF07991.12 KIR65708.1 - 0.044 13.4 0.2 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glyco_transf_4 PF13439.6 KIR65708.1 - 0.054 13.5 0.8 0.31 11.0 0.1 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Rossmann-like PF10727.9 KIR65708.1 - 0.059 13.2 0.8 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 Rossmann-like domain Lycopene_cycl PF05834.12 KIR65708.1 - 0.075 12.1 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KIR65708.1 - 0.11 12.8 0.2 0.2 11.9 0.2 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KIR65708.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KIR65708.1 - 0.14 12.5 1.2 0.58 10.5 0.1 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIR65709.1 - 1.2e-25 90.0 0.1 1.8e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 KIR65709.1 - 3.9e-08 33.0 0.0 1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-C domain XdhC_C PF13478.6 KIR65709.1 - 0.00019 21.9 0.1 0.00029 21.3 0.1 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain DAO PF01266.24 KIR65709.1 - 0.00057 19.6 1.0 0.013 15.1 1.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIR65709.1 - 0.00088 18.9 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIR65709.1 - 0.002 18.1 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIR65709.1 - 0.002 17.4 0.1 0.0025 17.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain F420_oxidored PF03807.17 KIR65709.1 - 0.0027 18.2 0.1 0.019 15.5 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIR65709.1 - 0.0029 17.3 0.1 0.0046 16.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KIR65709.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 KIR65709.1 - 0.0042 16.9 1.2 0.0079 16.0 0.2 1.9 1 1 2 3 3 3 1 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KIR65709.1 - 0.0044 17.3 0.1 0.0063 16.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KIR65709.1 - 0.011 16.1 0.1 0.018 15.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KIR65709.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 KIR65709.1 - 0.026 14.0 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIR65709.1 - 0.029 14.9 0.1 0.073 13.6 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIR65709.1 - 0.046 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiA PF01656.23 KIR65709.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_transf_4 PF13439.6 KIR65709.1 - 0.1 12.6 0.5 1.1 9.2 0.4 2.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_8 PF13450.6 KIR65709.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KIR65709.1 - 0.13 11.6 0.1 0.32 10.3 0.1 1.6 2 0 0 2 2 2 0 ThiF family AA_permease_2 PF13520.6 KIR65710.1 - 3.3e-27 95.4 33.1 4.6e-27 94.9 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease K_trans PF02705.16 KIR65710.1 - 0.0048 15.5 20.9 0.03 12.8 1.0 2.5 3 0 0 3 3 3 2 K+ potassium transporter AnmK PF03702.14 KIR65711.1 - 1.3e-114 383.1 0.1 1.5e-114 383.0 0.1 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase DXP_synthase_N PF13292.6 KIR65712.1 - 1e-109 366.0 0.0 1.5e-109 365.4 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 KIR65712.1 - 2.3e-36 125.1 0.1 5.7e-36 123.8 0.1 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIR65712.1 - 4.4e-23 81.5 0.4 1.6e-22 79.7 0.4 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KIR65712.1 - 1.1e-08 35.0 1.7 1.4e-06 28.2 0.4 3.6 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KIR65712.1 - 7.5e-06 25.1 0.1 0.00092 18.2 0.0 2.2 2 0 0 2 2 2 2 Dehydrogenase E1 component PFOR_II PF17147.4 KIR65712.1 - 1.1e-05 25.6 0.3 2.7e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_N PF00456.21 KIR65712.1 - 0.12 11.3 1.4 1.7 7.5 0.0 2.9 2 1 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain Peptidase_U4 PF03419.13 KIR65714.1 - 1.1 8.5 3.3 0.99 8.6 0.7 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA IspD PF01128.19 KIR65715.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CPP1-like PF11833.8 KIR65715.1 - 2.4 7.8 19.0 0.12 12.0 3.3 2.8 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PQQ_2 PF13360.6 KIR65716.1 - 4.8e-08 32.9 18.1 1.5e-05 24.7 3.5 3.5 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 KIR65716.1 - 0.001 18.9 0.3 0.73 9.9 0.0 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 KIR65716.1 - 0.38 11.3 0.1 0.38 11.3 0.1 6.5 6 1 0 6 6 6 0 PQQ-like domain Response_reg PF00072.24 KIR65717.1 - 3.2e-24 85.2 0.0 5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR65717.1 - 3.4e-20 71.9 0.0 6e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Glyoxalase_6 PF18029.1 KIR65718.1 - 3.4e-29 101.8 0.5 3.9e-29 101.6 0.5 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain DUF5056 PF16479.5 KIR65719.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF4366 PF14283.6 KIR65719.1 - 0.09 12.8 0.7 0.24 11.4 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) 3HCDH_N PF02737.18 KIR65720.1 - 1.2e-57 194.7 0.5 2e-57 194.0 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 KIR65720.1 - 3.7e-22 78.9 0.0 8.6e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR65720.1 - 1.4e-15 57.6 0.0 2.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 KIR65720.1 - 7.3e-12 45.7 0.0 4.9e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Thiolase_N PF00108.23 KIR65721.1 - 1.2e-58 198.6 0.1 1.5e-58 198.2 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR65721.1 - 4.3e-36 123.3 2.6 4.4e-36 123.2 0.0 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR65721.1 - 0.04 13.5 2.8 0.069 12.7 2.4 1.6 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DNA_pol_A_exo1 PF01612.20 KIR65722.1 - 8.8e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exoN PF18305.1 KIR65722.1 - 3.8e-28 97.6 1.0 3.8e-28 97.6 1.0 2.2 2 0 0 2 2 2 1 3' to 5' exonuclease C-terminal domain HRDC PF00570.23 KIR65722.1 - 2.8e-15 56.1 1.2 4.4e-15 55.4 0.2 1.9 2 0 0 2 2 2 1 HRDC domain Trypsin_2 PF13365.6 KIR65723.1 - 3.6e-20 73.4 3.7 1e-19 71.9 3.7 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KIR65723.1 - 1.8e-07 31.2 0.2 3e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 KIR65723.1 - 0.049 13.4 0.2 0.093 12.6 0.2 1.4 1 1 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 KIR65723.1 - 0.16 10.6 0.1 0.24 10.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase S46 LMBR1 PF04791.16 KIR65724.1 - 0.0018 17.3 0.2 0.0022 17.0 0.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein OmpH PF03938.14 KIR65724.1 - 0.0099 16.2 2.7 0.016 15.6 2.7 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) SesA PF17107.5 KIR65724.1 - 0.018 15.2 1.2 0.026 14.7 1.2 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CENP-F_leu_zip PF10473.9 KIR65724.1 - 0.024 14.7 1.4 0.032 14.2 1.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KIR65724.1 - 0.077 13.4 4.9 0.1 13.0 4.9 1.1 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.12 KIR65724.1 - 0.094 12.8 1.5 0.15 12.1 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 KIR65724.1 - 0.12 12.8 5.5 0.055 13.8 2.4 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Nsp1_C PF05064.13 KIR65724.1 - 0.14 11.9 0.7 0.22 11.3 0.7 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region FH2 PF02181.23 KIR65724.1 - 0.17 11.0 1.7 0.22 10.6 1.7 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Mer2 PF09074.10 KIR65724.1 - 0.18 11.6 2.3 0.24 11.2 2.3 1.1 1 0 0 1 1 1 0 Mer2 Spc7 PF08317.11 KIR65724.1 - 0.23 10.3 3.4 0.29 9.9 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KIR65724.1 - 0.35 11.0 1.3 0.49 10.5 1.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cytochrom_B562 PF07361.11 KIR65724.1 - 1 10.0 3.9 1.6 9.4 3.9 1.2 1 0 0 1 1 1 0 Cytochrome b562 GrpE PF01025.19 KIR65724.1 - 1.2 8.7 5.3 1.6 8.4 5.3 1.1 1 0 0 1 1 1 0 GrpE DUF4407 PF14362.6 KIR65724.1 - 2.3 7.5 8.7 4.2 6.6 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KIR65724.1 - 2.5 5.9 3.2 3.2 5.5 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3000 PF11452.8 KIR65725.1 - 1.2e-71 239.9 0.2 1.3e-71 239.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3000) URO-D PF01208.17 KIR65726.1 - 6e-128 426.8 0.0 6.7e-128 426.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Amino_oxidase PF01593.24 KIR65727.1 - 1e-47 163.5 3.0 1.2e-47 163.3 3.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR65727.1 - 1e-10 41.7 1.0 2.3e-10 40.5 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR65727.1 - 1.5e-07 31.4 16.2 5.5e-06 26.2 16.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR65727.1 - 1.1e-05 25.5 2.7 0.00036 20.5 0.5 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIR65727.1 - 2.2e-05 23.8 0.7 0.005 16.1 1.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KIR65727.1 - 0.006 15.4 0.1 0.0084 14.9 0.1 1.1 1 0 0 1 1 1 1 MCRA family HI0933_like PF03486.14 KIR65727.1 - 0.0061 15.3 0.6 0.022 13.5 0.9 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KIR65727.1 - 0.0089 15.4 3.3 0.015 14.7 3.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIR65727.1 - 0.03 13.6 0.9 0.051 12.8 0.9 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KIR65727.1 - 0.045 12.8 10.9 0.024 13.7 3.3 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KIR65727.1 - 0.046 14.3 0.8 0.13 12.8 0.8 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIR65727.1 - 0.42 9.4 1.4 0.58 8.9 1.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Chlor_dismutase PF06778.12 KIR65728.1 - 8.8e-75 250.6 0.2 1.1e-74 250.3 0.2 1.1 1 0 0 1 1 1 1 Chlorite dismutase LPMO_10 PF03067.15 KIR65729.1 - 3.2e-34 119.3 2.1 3.2e-34 119.3 2.1 1.4 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_2 PF00553.19 KIR65729.1 - 6.9e-24 84.1 14.0 6.9e-24 84.1 14.0 2.1 2 0 0 2 2 2 1 Cellulose binding domain Acetyltransf_10 PF13673.7 KIR65730.1 - 2.9e-14 53.1 0.0 4.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65730.1 - 1.6e-07 31.6 0.1 2e-07 31.3 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65730.1 - 1.4e-05 25.3 0.1 1.6e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIR65730.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65730.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Zn_Tnp_IS1595 PF12760.7 KIR65731.1 - 0.0024 17.8 9.3 0.081 12.9 4.7 2.1 1 1 1 2 2 2 2 Transposase zinc-ribbon domain Metallothio_Pro PF02069.16 KIR65731.1 - 0.036 14.3 3.1 0.036 14.3 3.1 2.2 1 1 1 2 2 2 0 Prokaryotic metallothionein zf-UBR PF02207.20 KIR65731.1 - 1.6 9.0 11.9 0.35 11.1 8.1 1.8 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AMPK1_CBM PF16561.5 KIR65732.1 - 3.1e-07 30.5 0.0 3.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KIR65732.1 - 0.01 16.1 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SelR PF01641.18 KIR65733.1 - 9.5e-51 171.0 0.0 1.1e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.9 KIR65733.1 - 0.00038 19.4 0.1 0.25 10.1 0.0 2.0 1 1 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_L37e PF01907.19 KIR65733.1 - 0.0049 17.0 4.1 0.19 11.9 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L37e Tnp_zf-ribbon_2 PF13842.6 KIR65733.1 - 0.0056 17.5 0.8 0.23 12.3 0.1 2.3 2 0 0 2 2 2 1 DDE_Tnp_1-like zinc-ribbon Zn_ribbon_SprT PF17283.2 KIR65733.1 - 0.0065 16.3 0.9 0.95 9.4 0.0 2.3 2 0 0 2 2 2 1 SprT-like zinc ribbon domain HypA PF01155.19 KIR65733.1 - 0.013 15.5 0.1 0.028 14.4 0.1 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 KIR65733.1 - 0.038 14.0 2.1 0.3 11.1 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF678 PF05077.12 KIR65733.1 - 0.038 14.1 0.0 11 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Yippee-Mis18 PF03226.14 KIR65733.1 - 0.041 14.1 0.2 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 KIR65733.1 - 0.051 13.3 0.2 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 KIR65733.1 - 0.09 12.7 0.9 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KIR65733.1 - 0.094 12.8 4.0 0.38 10.8 0.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KIR65733.1 - 0.17 11.4 4.8 6.3 6.4 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain DNA_primase_S PF01896.19 KIR65734.1 - 0.00075 19.6 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 DNA primase small subunit Ribosomal_L12 PF00542.19 KIR65735.1 - 5.1e-05 23.5 0.0 7.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain DUF4733 PF15878.5 KIR65735.1 - 0.0079 16.6 0.1 0.0088 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4733) Neurensin PF14927.6 KIR65735.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 Neurensin FtsX PF02687.21 KIR65736.1 - 3.3e-07 30.7 14.0 0.00052 20.4 2.0 3.9 4 0 0 4 4 4 2 FtsX-like permease family DUF4112 PF13430.6 KIR65736.1 - 0.071 13.4 0.2 6.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) ABC_tran PF00005.27 KIR65737.1 - 1.4e-26 93.6 0.0 2.2e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 KIR65737.1 - 7.9e-06 25.6 0.1 0.027 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KIR65737.1 - 2.5e-05 24.2 0.5 0.0073 16.2 1.5 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR65737.1 - 3.3e-05 23.4 0.0 0.029 13.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIR65737.1 - 6.4e-05 22.7 1.8 0.22 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIR65737.1 - 0.00014 22.2 0.4 0.0061 16.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KIR65737.1 - 0.00037 20.2 0.1 0.00068 19.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIR65737.1 - 0.00041 20.4 0.2 0.0012 18.9 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR65737.1 - 0.00054 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIR65737.1 - 0.0019 18.6 2.0 0.0048 17.3 2.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIR65737.1 - 0.0021 18.3 3.1 0.03 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 KIR65737.1 - 0.016 15.3 0.2 0.031 14.4 0.2 1.4 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 KIR65737.1 - 0.017 15.6 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIR65737.1 - 0.035 13.5 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KIR65737.1 - 0.043 14.1 0.1 0.13 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIR65737.1 - 0.066 12.6 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Ploopntkinase3 PF18751.1 KIR65737.1 - 0.075 12.9 0.3 3 7.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 KIR65737.1 - 0.11 12.0 0.1 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 KIR65737.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KIR65737.1 - 0.16 12.5 1.7 0.37 11.3 0.2 2.3 2 1 1 3 3 3 0 AAA domain Acetyltransf_1 PF00583.25 KIR65738.1 - 1e-17 64.5 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR65738.1 - 2.3e-12 47.2 0.0 3.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR65738.1 - 1.2e-10 41.4 0.0 2.1e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65738.1 - 5.1e-05 23.2 0.1 8e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIR65738.1 - 0.00023 21.3 0.0 0.0004 20.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIR65738.1 - 0.00054 20.7 0.0 0.00064 20.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65738.1 - 0.0014 18.7 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KIR65738.1 - 0.011 15.4 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ion_trans_2 PF07885.16 KIR65739.1 - 6.7e-15 54.8 3.4 9.4e-15 54.4 3.4 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KIR65739.1 - 0.00022 20.5 0.2 0.00033 20.0 0.2 1.3 1 1 0 1 1 1 1 Ion transport protein Abhydrolase_1 PF00561.20 KIR65740.1 - 9.4e-41 140.1 0.0 1.5e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIR65740.1 - 5.3e-24 84.3 0.0 1.8e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KIR65740.1 - 0.00021 20.7 0.0 0.00042 19.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KIR65740.1 - 0.046 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DNA_ligase_A_M PF01068.21 KIR65741.1 - 3.3e-36 124.9 0.0 4.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 KIR65741.1 - 8.5e-16 58.4 0.0 1.8e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KIR65741.1 - 0.00054 20.3 0.0 0.00083 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KIR65741.1 - 0.0015 18.4 0.0 12 5.6 0.0 3.1 3 0 0 3 3 3 3 mRNA capping enzyme, catalytic domain Polyketide_cyc2 PF10604.9 KIR65743.1 - 1.1e-15 58.1 3.1 1.2e-15 58.0 3.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR65743.1 - 1.8e-07 31.4 0.7 3e-07 30.7 0.7 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIR65743.1 - 0.034 14.4 0.1 0.041 14.1 0.1 1.1 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Acetyltransf_10 PF13673.7 KIR65744.1 - 2.5e-16 59.7 0.0 2.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR65744.1 - 1.2e-11 44.9 0.1 1.6e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR65744.1 - 2.2e-11 44.0 0.1 3.4e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR65744.1 - 5.8e-08 32.9 0.0 7.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65744.1 - 0.00021 21.2 0.1 0.00032 20.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KIR65744.1 - 0.00059 19.6 0.2 0.00078 19.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ DUF1990 PF09348.10 KIR65745.1 - 1.5e-51 174.4 2.0 1.8e-51 174.2 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) HhH-GPD PF00730.25 KIR65746.1 - 0.0033 17.8 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 KIR65746.1 - 0.12 13.0 0.1 0.29 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_8 PF14716.6 KIR65746.1 - 0.16 12.4 1.8 0.32 11.4 0.5 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Lipoprotein_15 PF03640.15 KIR65747.1 - 2.9e-31 106.7 7.4 2.5e-16 58.9 2.4 2.5 2 0 0 2 2 2 2 Secreted repeat of unknown function LPAM_1 PF08139.12 KIR65747.1 - 0.035 14.6 1.1 0.07 13.7 1.1 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site MAR_sialic_bdg PF10564.9 KIR65747.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat zf-HC2 PF13490.6 KIR65748.1 - 6.6e-05 23.1 1.9 6.6e-05 23.1 1.9 2.2 3 0 0 3 3 3 1 Putative zinc-finger Sigma70_r2 PF04542.14 KIR65749.1 - 1.5e-15 56.7 0.4 2.8e-15 55.8 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR65749.1 - 1.1e-11 44.1 0.2 1.9e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIR65749.1 - 1.8e-08 33.9 0.1 3e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR65749.1 - 4.7e-05 23.4 1.3 7.2e-05 22.8 1.3 1.3 1 0 0 1 1 1 1 ECF sigma factor HTH_28 PF13518.6 KIR65749.1 - 0.017 15.3 0.1 0.051 13.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain ADSL_C PF10397.9 KIR65749.1 - 0.027 15.0 0.1 0.056 14.0 0.1 1.5 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Methyltransf_11 PF08241.12 KIR65750.1 - 9.5e-05 23.0 0.0 0.00017 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 KIR65750.1 - 0.00059 19.3 0.0 0.00079 18.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KIR65750.1 - 0.0006 20.5 0.0 0.0013 19.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIR65750.1 - 0.097 13.7 0.0 0.28 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain AAA_23 PF13476.6 KIR65752.1 - 2.3e-18 67.4 0.0 5.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KIR65752.1 - 5.7e-13 48.9 0.7 1.8e-12 47.4 0.7 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KIR65752.1 - 3.4e-11 43.0 0.0 1.4e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR65752.1 - 5.5e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIR65752.1 - 3.3e-05 24.4 0.0 0.0049 17.4 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_27 PF13514.6 KIR65752.1 - 0.0005 19.7 0.0 0.0005 19.7 0.0 4.7 4 1 1 5 5 5 1 AAA domain AAA_21 PF13304.6 KIR65752.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIR65752.1 - 0.069 12.9 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIR65752.1 - 0.11 12.8 0.0 0.56 10.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF4201 PF13870.6 KIR65752.1 - 0.56 9.9 5.3 0.18 11.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF2353 PF09789.9 KIR65752.1 - 0.73 9.1 3.2 1.6 8.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Metallophos PF00149.28 KIR65753.1 - 2.7e-11 44.3 0.0 3.7e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR65753.1 - 3.1e-09 37.3 0.1 1.6e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SbcD_C PF12320.8 KIR65753.1 - 8.4e-07 29.2 0.2 2.2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Type 5 capsule protein repressor C-terminal domain Epimerase_2 PF02350.19 KIR65753.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF834 PF05754.14 KIR65753.1 - 0.017 15.1 1.7 0.34 10.9 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF834) Peptidase_M4_C PF02868.15 KIR65754.1 - 2.4e-52 177.2 0.4 4.9e-52 176.2 0.4 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KIR65754.1 - 2.6e-50 170.7 7.0 5.9e-50 169.6 7.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain FTP PF07504.13 KIR65754.1 - 1.4e-14 53.6 0.1 3.7e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 KIR65754.1 - 0.0034 17.9 0.6 0.008 16.7 0.1 1.9 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain PRiA4_ORF3 PF07929.11 KIR65755.1 - 2.5e-63 212.9 0.0 2.8e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein SBP_bac_8 PF13416.6 KIR65757.1 - 2.8e-32 112.7 9.7 4.2e-32 112.1 9.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR65757.1 - 2.5e-22 80.3 11.7 2.5e-22 80.3 11.7 1.7 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR65757.1 - 1.8e-05 24.6 0.2 0.24 11.1 0.0 2.8 3 1 0 3 3 3 2 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR65757.1 - 6.7e-05 22.4 0.5 0.00041 19.8 0.3 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR65758.1 - 3.7e-18 65.9 19.0 3.7e-18 65.9 19.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 KIR65758.1 - 3.6 7.8 7.1 2.1 8.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) FtsX PF02687.21 KIR65758.1 - 5.1 7.6 21.3 0.28 11.7 3.8 3.5 3 1 0 3 3 3 0 FtsX-like permease family BPD_transp_1 PF00528.22 KIR65759.1 - 1.7e-20 73.6 13.6 1.7e-20 73.6 13.6 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4064 PF13273.6 KIR65759.1 - 0.24 11.7 8.7 0.04 14.2 1.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1658 PF07871.11 KIR65759.1 - 2.4 8.2 5.1 5.7 7.1 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Glyco_hydro_1 PF00232.18 KIR65760.1 - 7.5e-164 545.4 0.0 9.3e-164 545.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Topo_C_assoc PF14370.6 KIR65760.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal topoisomerase domain Acyl-CoA_dh_1 PF00441.24 KIR65761.1 - 1.2e-35 122.9 3.9 2e-35 122.2 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR65761.1 - 9.6e-22 77.0 0.0 1.6e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIR65761.1 - 5.7e-13 49.3 2.1 5.7e-13 49.3 2.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR65761.1 - 3.8e-12 46.9 0.6 1.2e-11 45.3 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Cyclase PF04199.13 KIR65761.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative cyclase APH PF01636.23 KIR65762.1 - 6e-42 144.2 4.6 8.9e-42 143.7 4.6 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ACT PF01842.25 KIR65763.1 - 0.00035 20.3 0.7 0.00066 19.4 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 KIR65763.1 - 0.00076 20.0 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 ACT domain Acetyltransf_1 PF00583.25 KIR65764.1 - 3e-08 33.9 0.1 8.9e-08 32.4 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family ACT PF01842.25 KIR65764.1 - 3.6e-06 26.6 0.1 9.6e-06 25.3 0.1 1.8 1 0 0 1 1 1 1 ACT domain Acetyltransf_3 PF13302.7 KIR65764.1 - 4.8e-05 24.1 0.0 9.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR65764.1 - 0.00011 22.1 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR65764.1 - 0.0015 18.4 0.4 0.0054 16.7 0.2 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 KIR65764.1 - 0.0019 18.6 0.0 0.0059 17.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ACT_6 PF13740.6 KIR65764.1 - 0.0052 16.7 0.1 0.025 14.5 0.1 2.2 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 KIR65764.1 - 0.055 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain Acetyltransf_6 PF13480.7 KIR65764.1 - 4.8 7.3 12.0 0.26 11.4 3.2 2.5 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Gram_pos_anchor PF00746.21 KIR65765.1 - 0.018 15.0 1.6 0.035 14.0 1.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Trypan_PARP PF05887.11 KIR65765.1 - 0.18 11.8 14.8 0.061 13.3 11.9 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.10 KIR65765.1 - 1.1 7.9 2.1 1.6 7.3 2.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BES1_N PF05687.13 KIR65765.1 - 2.4 8.5 4.9 4.1 7.8 4.9 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Glyco_hydro_9 PF00759.19 KIR65766.1 - 9e-140 466.7 26.1 1.4e-139 466.1 26.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_2 PF00553.19 KIR65766.1 - 3.2e-31 107.6 11.1 3.2e-31 107.6 11.1 3.6 4 0 0 4 4 4 1 Cellulose binding domain fn3 PF00041.21 KIR65766.1 - 2.4e-24 85.5 7.8 3.6e-12 46.5 0.2 2.8 2 0 0 2 2 2 2 Fibronectin type III domain CBM_3 PF00942.18 KIR65766.1 - 5.8e-08 33.0 0.0 1.2e-06 28.8 0.0 2.8 2 0 0 2 2 2 1 Cellulose binding domain fn3_2 PF16893.5 KIR65766.1 - 1.2e-05 25.4 0.1 0.0069 16.5 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain DUF2369 PF10179.9 KIR65766.1 - 0.00096 19.5 0.0 0.54 10.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) C1_1 PF00130.22 KIR65767.1 - 0.011 15.5 1.4 2.4 8.1 0.1 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 KIR65767.1 - 0.07 12.7 1.2 7 6.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KIR65767.1 - 0.096 12.7 4.4 0.37 10.8 4.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon Radical_SAM PF04055.21 KIR65768.1 - 1.8e-15 57.7 0.1 5.4e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily BATS PF06968.13 KIR65768.1 - 7.6e-12 45.2 0.0 2.2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain His_biosynth PF00977.21 KIR65768.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein p450 PF00067.22 KIR65769.1 - 1e-19 70.6 0.0 1.4e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 PrmA PF06325.13 KIR65770.1 - 2.9e-09 36.8 3.1 3.6e-09 36.4 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIR65770.1 - 4.8e-08 32.7 0.2 6.6e-08 32.3 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIR65770.1 - 4e-06 27.4 0.9 8.5e-06 26.4 0.9 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KIR65770.1 - 1.6e-05 24.7 0.0 3.1e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 KIR65770.1 - 0.00047 19.8 0.5 0.00067 19.3 0.5 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KIR65770.1 - 0.0017 19.0 0.8 0.0027 18.3 0.8 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65770.1 - 0.045 13.6 0.0 0.055 13.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIR65770.1 - 0.062 13.1 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KIR65770.1 - 0.14 11.9 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein FA_desaturase PF00487.24 KIR65771.1 - 4.5e-31 108.6 25.8 7.6e-30 104.6 11.6 2.9 2 1 1 3 3 3 2 Fatty acid desaturase CPBP PF02517.16 KIR65771.1 - 0.013 15.8 3.3 0.4 11.1 0.5 2.6 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease TetR_C_6 PF13977.6 KIR65772.1 - 2.4e-22 79.3 3.8 2.4e-22 79.3 3.8 2.4 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 KIR65772.1 - 5.9e-13 48.4 0.2 5.9e-13 48.4 0.2 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 KIR65772.1 - 7.8e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 KIR65772.1 - 0.0049 17.1 0.4 0.01 16.1 0.0 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 KIR65772.1 - 0.04 14.0 1.1 0.14 12.2 0.1 2.3 2 1 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain SfLAP PF11139.8 KIR65773.1 - 0.0075 15.7 0.8 0.0077 15.7 0.8 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein DUF202 PF02656.15 KIR65773.1 - 0.74 10.3 4.4 1.1 9.8 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Glyco_hydro_3 PF00933.21 KIR65774.1 - 2.2e-29 102.9 0.0 4.5e-28 98.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIR65774.1 - 2.6e-28 99.4 0.1 4.4e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIR65774.1 - 1.2e-15 57.3 1.1 8.8e-15 54.6 0.1 2.8 3 0 0 3 3 3 1 Fibronectin type III-like domain Big_2 PF02368.18 KIR65774.1 - 5.2e-08 32.7 8.6 1e-06 28.5 0.8 3.2 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 2) RQC PF09382.10 KIR65775.1 - 5.1e-35 119.7 0.0 8.7e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 KIR65775.1 - 7.9e-23 80.2 0.0 1.5e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 KIR65775.1 - 1.5e-18 67.2 0.0 2.8e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIR65775.1 - 7.7e-18 65.0 0.9 1.4e-17 64.1 0.9 1.5 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 KIR65775.1 - 1.4e-17 64.1 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glycos_transf_N PF04413.16 KIR65775.1 - 0.17 11.5 0.4 0.5 10.0 0.3 1.8 1 1 1 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) TetR_N PF00440.23 KIR65776.1 - 1.6e-08 34.2 0.3 3.5e-08 33.1 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 KIR65776.1 - 0.00048 20.4 6.8 0.00048 20.4 6.8 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_21 PF17926.1 KIR65776.1 - 0.0033 17.6 1.1 0.0059 16.7 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NmrA PF05368.13 KIR65777.1 - 5.8e-46 156.9 0.0 8.7e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIR65777.1 - 5.6e-24 85.0 0.5 7.5e-24 84.6 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIR65777.1 - 6.2e-09 35.7 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR65777.1 - 1.7e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIR65777.1 - 0.00068 19.1 0.0 0.00097 18.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIR65777.1 - 0.01 15.3 0.3 0.016 14.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KIR65778.1 - 5.2e-06 26.1 0.0 0.0018 17.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF664 PF04978.12 KIR65780.1 - 6.8e-44 149.9 1.4 7.9e-44 149.7 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR65780.1 - 3e-12 47.2 1.6 4.2e-12 46.7 1.6 1.1 1 0 0 1 1 1 1 DinB superfamily TAT_signal PF10518.9 KIR65781.1 - 0.013 15.3 5.2 0.013 15.3 5.2 2.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Response_reg PF00072.24 KIR65782.1 - 6.2e-23 81.1 0.0 9.8e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR65782.1 - 7.9e-19 67.0 0.4 1.3e-18 66.3 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR65782.1 - 2.2e-07 30.4 0.5 1e-06 28.3 0.2 2.1 1 1 1 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR65782.1 - 0.0022 17.5 0.1 0.0056 16.2 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR65782.1 - 0.0025 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 KIR65782.1 - 0.0031 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR65782.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain GAF_2 PF13185.6 KIR65783.1 - 1.1e-28 100.2 13.2 1.5e-16 60.9 0.1 3.7 4 0 0 4 4 4 2 GAF domain GAF PF01590.26 KIR65783.1 - 2.7e-21 76.6 1.3 4.1e-13 50.1 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KIR65783.1 - 6.2e-20 71.9 0.5 2.5e-08 34.3 0.3 3.1 2 2 0 2 2 2 2 GAF domain HisKA_3 PF07730.13 KIR65783.1 - 2.7e-13 50.2 1.5 2.7e-13 50.2 1.5 3.0 3 0 0 3 3 3 1 Histidine kinase HATPase_c_2 PF13581.6 KIR65783.1 - 1.4e-08 34.7 1.0 3.8e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR65783.1 - 1e-06 29.2 0.0 1.7e-05 25.3 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 KIR65783.1 - 0.0052 17.1 0.2 0.9 10.0 0.2 3.1 3 0 0 3 3 3 1 Signal transducing histidine kinase, homodimeric domain Nitroreductase PF00881.24 KIR65784.1 - 2.1e-09 37.6 5.1 0.00062 19.8 0.1 3.7 2 2 1 3 3 3 3 Nitroreductase family TM1586_NiRdase PF14512.6 KIR65784.1 - 0.24 10.9 0.0 0.48 9.9 0.0 1.5 2 0 0 2 2 2 0 Putative TM nitroreductase Hydrolase PF00702.26 KIR65785.1 - 9.3e-36 124.1 1.3 9.3e-36 124.1 1.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIR65785.1 - 1.5e-33 115.9 0.6 1.5e-33 115.9 0.6 2.8 3 0 0 3 3 3 2 E1-E2 ATPase Hemerythrin PF01814.23 KIR65785.1 - 1.7e-16 61.0 1.1 1.7e-16 61.0 1.1 2.3 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain HAD PF12710.7 KIR65785.1 - 0.0028 18.1 0.2 0.0028 18.1 0.2 3.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR65785.1 - 0.021 14.6 0.9 0.11 12.2 0.5 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Usp PF00582.26 KIR65786.1 - 4.3e-57 192.6 8.9 4.3e-29 101.8 3.1 2.1 2 0 0 2 2 2 2 Universal stress protein family XFP_N PF09364.10 KIR65787.1 - 7.8e-178 590.8 0.0 1e-177 590.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KIR65787.1 - 1.4e-95 318.5 0.0 2e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KIR65787.1 - 7.9e-89 296.0 0.0 1.1e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KIR65787.1 - 0.018 14.8 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Usp PF00582.26 KIR65788.1 - 1.8e-29 103.0 14.2 1e-18 68.2 2.8 2.3 2 1 0 2 2 2 2 Universal stress protein family DUF2855 PF11017.8 KIR65788.1 - 0.24 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) HTH_11 PF08279.12 KIR65789.1 - 6.2e-05 22.9 0.1 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 HTH domain HTH_23 PF13384.6 KIR65789.1 - 7.3e-05 22.4 1.1 0.00029 20.5 1.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR65789.1 - 0.00031 20.4 0.1 0.0041 16.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.6 KIR65789.1 - 0.001 18.8 4.3 0.017 15.0 0.4 2.6 1 1 1 2 2 2 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 KIR65789.1 - 0.002 17.6 0.1 0.038 13.5 0.0 2.1 1 1 1 2 2 2 1 Sigma-70, region 4 UPF0122 PF04297.14 KIR65789.1 - 0.0054 16.9 0.0 0.0064 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_3 PF01381.22 KIR65789.1 - 0.0088 16.1 0.0 0.068 13.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_ECF PF07638.11 KIR65789.1 - 0.013 15.5 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 ECF sigma factor Terminase_5 PF06056.12 KIR65789.1 - 0.051 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 KIR65789.1 - 0.062 13.4 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF433 PF04255.14 KIR65789.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) HTH_15 PF12324.8 KIR65789.1 - 0.16 12.0 0.3 1.1 9.2 0.3 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase HTH_31 PF13560.6 KIR65789.1 - 0.52 10.7 7.7 0.5 10.7 5.1 2.1 1 1 2 3 3 3 0 Helix-turn-helix domain Clp_N PF02861.20 KIR65790.1 - 1.5e-28 98.7 17.1 1.2e-15 57.3 2.2 3.4 3 1 0 3 3 3 3 Clp amino terminal domain, pathogenicity island component DUF3572 PF12096.8 KIR65790.1 - 0.00075 19.6 1.8 0.046 13.9 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3572) TFIID_30kDa PF03540.13 KIR65790.1 - 0.15 12.0 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Virul_fac_BrkB PF03631.15 KIR65791.1 - 1.8e-41 142.5 13.2 2e-41 142.3 13.2 1.0 1 0 0 1 1 1 1 Virulence factor BrkB PAP2 PF01569.21 KIR65792.1 - 1.7e-30 105.6 37.6 4e-18 65.5 8.9 3.8 4 2 1 5 5 5 2 PAP2 superfamily PAP2_3 PF14378.6 KIR65792.1 - 7.2e-09 35.6 36.6 2e-05 24.4 11.0 3.8 3 2 0 3 3 3 2 PAP2 superfamily Phage_holin_8 PF16931.5 KIR65792.1 - 0.011 15.7 2.2 0.073 13.0 0.0 3.2 4 0 0 4 4 4 0 Putative phage holin PAP2_C PF14360.6 KIR65792.1 - 0.13 12.8 11.8 0.87 10.2 0.1 3.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Exo_endo_phos PF03372.23 KIR65793.1 - 1.2e-07 31.6 6.5 1.9e-07 30.9 6.5 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PspC PF04024.12 KIR65793.1 - 0.052 13.4 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 PspC domain Bac_luciferase PF00296.20 KIR65794.1 - 9.6e-53 179.6 2.4 1.2e-52 179.4 2.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PGM_PMM_II PF02879.16 KIR65794.1 - 0.14 12.7 0.1 0.4 11.3 0.1 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Cellulase PF00150.18 KIR65795.1 - 3.6e-37 128.3 2.8 4.8e-37 127.9 2.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_2 PF00553.19 KIR65795.1 - 9.1e-26 90.1 12.7 9.1e-26 90.1 12.7 2.3 2 0 0 2 2 2 1 Cellulose binding domain DeoC PF01791.9 KIR65795.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase Mito_fiss_reg PF05308.11 KIR65795.1 - 2.2 8.3 3.5 3.5 7.6 3.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MerR_1 PF13411.6 KIR65796.1 - 1.9e-14 53.5 0.0 3.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein PP2C_2 PF13672.6 KIR65796.1 - 1.3e-09 38.0 0.7 3.6e-09 36.6 0.7 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C MerR PF00376.23 KIR65796.1 - 6.9e-09 35.3 0.2 1.8e-08 34.0 0.2 1.8 1 0 0 1 1 1 1 MerR family regulatory protein PP2C PF00481.21 KIR65796.1 - 8.5e-06 25.6 0.0 2.7e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C MerR-DNA-bind PF09278.11 KIR65796.1 - 0.00015 22.2 0.3 0.00045 20.7 0.3 1.9 1 0 0 1 1 1 1 MerR, DNA binding HTH_35 PF13693.6 KIR65796.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Melibiase PF02065.18 KIR65797.1 - 3.6e-109 364.9 0.0 4.4e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KIR65797.1 - 8.6e-48 163.1 0.0 1.1e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KIR65797.1 - 1.2e-08 35.4 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain BPD_transp_1 PF00528.22 KIR65798.1 - 8.3e-17 61.5 11.5 8.3e-17 61.5 11.5 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR65799.1 - 1.2e-12 48.0 23.5 1.3e-11 44.6 23.5 2.2 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component MrpF_PhaF PF04066.13 KIR65799.1 - 0.026 14.9 0.1 0.026 14.9 0.1 3.5 3 0 0 3 3 3 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Oleosin PF01277.17 KIR65799.1 - 0.038 13.8 2.1 0.038 13.8 2.1 3.5 4 1 0 4 4 4 0 Oleosin SBP_bac_8 PF13416.6 KIR65800.1 - 4.2e-20 72.7 12.3 5.5e-20 72.3 12.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR65800.1 - 4.3e-19 69.6 15.9 5.9e-19 69.2 15.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR65800.1 - 0.00014 21.4 2.7 0.0036 16.8 2.6 2.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein TAT_signal PF10518.9 KIR65800.1 - 2.2 8.3 9.3 4.4 7.3 9.3 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Glyco_hydro_42 PF02449.15 KIR65801.1 - 6.1e-147 489.8 0.0 7.4e-147 489.6 0.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 KIR65801.1 - 8e-61 205.1 0.1 1.6e-60 204.2 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.10 KIR65801.1 - 9.7e-13 47.6 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Glyco_hydro_35 PF01301.19 KIR65801.1 - 0.00015 21.5 0.0 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_14 PF01373.17 KIR65801.1 - 0.00021 20.4 0.1 0.001 18.1 0.0 2.1 3 0 0 3 3 3 1 Glycosyl hydrolase family 14 Glyco_hydro_2_C PF02836.17 KIR65801.1 - 0.021 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4434 PF14488.6 KIR65801.1 - 0.024 14.6 0.0 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) DUF4350 PF14258.6 KIR65801.1 - 0.082 13.4 0.1 0.42 11.1 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) NiFeSe_Hases PF00374.19 KIR65801.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DUF3459 PF11941.8 KIR65801.1 - 0.57 10.5 8.9 0.2 12.0 0.3 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF3459) DeoRC PF00455.22 KIR65802.1 - 2.3e-49 167.4 0.1 2.9e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 KIR65802.1 - 2.3e-19 68.9 0.3 3.9e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KIR65802.1 - 1.3e-06 28.3 0.1 2.3e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 KIR65802.1 - 1.1e-05 25.2 0.5 5.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 MarR family GntR PF00392.21 KIR65802.1 - 3.5e-05 23.4 0.2 8.8e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KIR65802.1 - 7.1e-05 22.6 0.6 0.00026 20.8 0.6 1.9 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KIR65802.1 - 0.0048 17.2 0.1 0.22 11.9 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator HTH_20 PF12840.7 KIR65802.1 - 0.01 15.9 2.0 0.018 15.1 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_27 PF13463.6 KIR65802.1 - 0.016 15.7 0.1 0.037 14.5 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain CoA_trans PF01144.23 KIR65802.1 - 0.029 13.7 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 Coenzyme A transferase HTH_IclR PF09339.10 KIR65802.1 - 0.037 13.8 2.2 0.04 13.7 0.2 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR65802.1 - 0.062 12.9 0.1 0.37 10.4 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FaeA PF04703.12 KIR65802.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein HTH_5 PF01022.20 KIR65802.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HemN_C PF06969.16 KIR65802.1 - 0.087 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 HemN C-terminal domain TrmB PF01978.19 KIR65802.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3489 PF11994.8 KIR65802.1 - 0.17 12.0 0.3 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) HTH_23 PF13384.6 KIR65802.1 - 0.49 10.3 3.9 0.19 11.5 0.3 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Lipase_GDSL_2 PF13472.6 KIR65804.1 - 5e-24 85.7 1.4 5.7e-24 85.5 1.4 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR65804.1 - 7.5e-06 26.0 0.0 1.3e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TPR_12 PF13424.6 KIR65805.1 - 2e-13 50.4 15.7 1.7e-07 31.4 0.8 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIR65805.1 - 1.1e-05 25.1 14.5 7.5e-05 22.5 0.4 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIR65805.1 - 2.9e-05 23.6 10.2 4.7e-05 22.9 6.6 2.0 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KIR65805.1 - 0.0024 18.3 9.9 0.012 16.1 0.7 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIR65805.1 - 0.44 11.5 27.5 1.1 10.3 0.6 5.7 2 1 3 5 5 5 0 Tetratricopeptide repeat Glyoxalase PF00903.25 KIR65806.1 - 4.7e-16 59.2 0.0 6.6e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR65806.1 - 2.4e-06 28.3 0.1 3.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIR65806.1 - 9.7e-06 25.8 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KIR65806.1 - 0.0002 21.5 0.2 0.0078 16.3 0.2 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KIR65806.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Ion_trans_2 PF07885.16 KIR65808.1 - 2.1e-13 50.0 2.7 4.7e-13 48.9 2.7 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 KIR65808.1 - 0.00023 20.5 0.1 0.00039 19.7 0.1 1.4 2 0 0 2 2 2 1 Ion transport protein IRK PF01007.20 KIR65808.1 - 0.019 14.8 2.5 0.046 13.5 2.5 1.7 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Phage_holin_5_2 PF16079.5 KIR65808.1 - 0.45 10.9 4.7 0.28 11.5 1.4 2.1 1 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF4236 PF14020.6 KIR65809.1 - 1.8e-09 38.0 0.4 2.1e-09 37.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4236) Flavin_Reduct PF01613.18 KIR65810.1 - 1.5e-32 112.7 0.3 1.9e-32 112.5 0.3 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Rrf2 PF02082.20 KIR65811.1 - 1.8e-26 92.3 0.1 2.7e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 KIR65811.1 - 0.066 13.1 0.9 0.26 11.2 0.4 2.1 1 1 1 2 2 2 0 MarR family TrmB PF01978.19 KIR65811.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB adh_short_C2 PF13561.6 KIR65812.1 - 1.6e-55 188.3 0.4 1.9e-55 188.0 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR65812.1 - 1.8e-51 174.4 0.0 2.3e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR65812.1 - 9.9e-09 35.4 0.1 1.4e-08 34.9 0.1 1.3 1 1 0 1 1 1 1 KR domain TRI9 PF08195.11 KIR65812.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 TRI9 protein NAD_binding_7 PF13241.6 KIR65812.1 - 0.03 14.7 0.6 0.11 12.9 0.3 1.9 2 2 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_4 PF07993.12 KIR65812.1 - 0.036 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein ATPgrasp_N PF18130.1 KIR65812.1 - 0.056 14.0 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp N-terminal domain THF_DHG_CYH_C PF02882.19 KIR65812.1 - 0.14 11.5 1.0 0.92 8.8 0.0 2.4 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KIR65812.1 - 0.17 11.3 0.2 0.74 9.2 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SsgA PF04686.12 KIR65813.1 - 9.5e-36 121.7 0.1 1.4e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Streptomyces sporulation and cell division protein, SsgA HTH_31 PF13560.6 KIR65814.1 - 2.6e-10 40.5 4.6 2.6e-10 40.5 4.6 5.9 3 1 3 6 6 6 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65814.1 - 0.00048 20.1 0.5 0.0056 16.7 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix TPR_12 PF13424.6 KIR65814.1 - 0.008 16.4 5.9 0.008 16.4 5.9 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_19 PF12844.7 KIR65814.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Nre_C PF04895.12 KIR65814.1 - 0.44 10.5 2.1 0.87 9.5 0.3 2.2 2 0 0 2 2 2 0 Archaeal Nre, C-terminal GntR PF00392.21 KIR65815.1 - 5.5e-17 61.2 0.0 6.1e-17 61.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family PP2C_C PF07830.13 KIR65815.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Rrf2 PF02082.20 KIR65815.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_31 PF13560.6 KIR65816.1 - 4.7e-13 49.3 5.4 4.7e-13 49.3 5.4 4.1 5 0 0 5 5 5 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65816.1 - 2.7e-12 46.6 0.4 7.8e-12 45.1 0.4 1.9 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR65816.1 - 8.7e-10 38.5 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR65816.1 - 1.6e-05 25.2 0.0 4.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 KIR65816.1 - 0.00096 19.0 2.2 0.0042 16.9 2.2 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KIR65816.1 - 0.00098 18.6 0.5 0.0044 16.6 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 KIR65816.1 - 0.0059 16.5 1.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MerR PF00376.23 KIR65816.1 - 0.019 14.7 0.6 0.68 9.8 0.0 3.2 3 0 0 3 3 3 0 MerR family regulatory protein TPR_12 PF13424.6 KIR65816.1 - 0.026 14.8 1.7 0.026 14.8 1.7 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 KIR65816.1 - 0.027 14.0 1.6 0.19 11.3 1.7 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 GntR PF00392.21 KIR65816.1 - 0.054 13.1 0.5 2.5 7.8 0.4 2.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TPR_2 PF07719.17 KIR65816.1 - 0.18 12.0 5.4 12 6.3 0.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat Usp PF00582.26 KIR65816.1 - 2.2 8.8 7.2 0.53 10.8 1.1 3.0 2 1 1 3 3 3 0 Universal stress protein family HTH_31 PF13560.6 KIR65817.1 - 4.4e-09 36.5 3.0 4.4e-09 36.5 3.0 5.1 4 1 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65817.1 - 0.00063 19.8 0.0 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR65817.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SnoaL_2 PF12680.7 KIR65819.1 - 0.0015 19.2 1.7 0.0027 18.3 1.7 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 KIR65819.1 - 0.059 13.5 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain adh_short PF00106.25 KIR65820.1 - 1.5e-48 164.8 0.0 2e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR65820.1 - 1.3e-39 136.2 0.0 1.6e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR65820.1 - 1.4e-13 51.1 0.0 2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIR65820.1 - 7.6e-06 25.9 0.1 0.0011 18.9 0.0 2.3 2 1 0 2 2 2 2 NAD(P)H-binding TetR_N PF00440.23 KIR65821.1 - 5.7e-17 61.2 0.2 2e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 KIR65821.1 - 0.052 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase NAD_binding_10 PF13460.6 KIR65822.1 - 2.4e-24 86.3 1.3 3.4e-24 85.8 1.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR65822.1 - 9.3e-23 81.0 0.0 2.4e-22 79.6 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIR65822.1 - 2.7e-07 30.3 0.3 1.1e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65822.1 - 0.0016 17.9 0.0 0.0097 15.3 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIR65822.1 - 0.009 15.5 0.3 0.017 14.6 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KIR65822.1 - 0.0093 15.1 0.2 0.17 11.0 0.1 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KIR65822.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KIR65822.1 - 0.04 14.2 0.1 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 KIR65822.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SnoaL_2 PF12680.7 KIR65823.1 - 1.4e-10 41.7 0.2 1.8e-10 41.4 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KIR65823.1 - 0.00016 21.4 0.0 0.00045 20.0 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KIR65823.1 - 0.0002 21.7 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) MarR_2 PF12802.7 KIR65824.1 - 2.5e-12 46.5 3.1 8.9e-12 44.7 0.3 2.5 3 0 0 3 3 3 1 MarR family MarR PF01047.22 KIR65824.1 - 3.5e-07 30.0 0.0 1.1e-06 28.5 0.0 1.8 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 KIR65824.1 - 5.6e-07 30.0 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain TetR_N PF00440.23 KIR65825.1 - 1.4e-14 53.5 0.3 3e-14 52.5 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 KIR65825.1 - 6e-12 45.5 1.0 6e-12 45.5 1.0 1.6 2 0 0 2 2 2 1 MftR C-terminal domain TetR_C_11 PF16859.5 KIR65825.1 - 0.0007 19.9 4.4 0.0007 19.9 4.4 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_31 PF17940.1 KIR65825.1 - 3.2 8.0 13.1 0.43 10.8 7.1 2.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FAD_binding_3 PF01494.19 KIR65826.1 - 1.5e-20 73.8 5.5 4e-19 69.1 5.5 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIR65826.1 - 9.3e-06 25.8 0.3 2.3e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR65826.1 - 0.00096 18.8 0.3 0.0021 17.7 0.3 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR65826.1 - 0.0013 18.0 0.2 0.0029 16.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR65826.1 - 0.014 14.5 0.2 0.024 13.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KIR65826.1 - 0.072 13.7 0.2 0.18 12.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIR65826.1 - 0.081 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KIR65826.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TetR_C_1 PF02909.17 KIR65827.1 - 3.6e-13 49.6 0.1 5.6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65827.1 - 5.9e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 KIR65827.1 - 0.00094 18.9 0.1 0.007 16.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KIR65827.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain adh_short PF00106.25 KIR65828.1 - 2.3e-26 92.4 0.1 1.4e-25 89.9 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR65828.1 - 1.9e-18 66.9 0.1 2.4e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR65828.1 - 3.7e-06 27.0 1.6 7.2e-06 26.0 1.6 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR65828.1 - 0.00034 20.2 0.1 0.00046 19.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 KIR65828.1 - 0.087 12.1 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MLTR_LBD PF17765.1 KIR65829.1 - 5.3e-50 169.8 3.0 5.3e-50 169.8 3.0 1.8 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KIR65829.1 - 3.2e-17 62.6 7.9 3.2e-17 62.6 7.9 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65829.1 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR65829.1 - 0.17 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ricin_B_lectin PF00652.22 KIR65830.1 - 2.1e-30 105.6 6.4 3.1e-30 105.0 6.4 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR65830.1 - 5.7e-25 87.9 14.9 7.7e-13 49.0 0.5 3.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Lipase_GDSL_2 PF13472.6 KIR65830.1 - 4e-17 63.2 1.4 8.4e-17 62.1 1.4 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR65830.1 - 4.6e-11 43.1 0.1 9e-11 42.1 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KIR65830.1 - 0.0023 18.1 0.0 0.0033 17.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KIR65830.1 - 0.16 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 OSK domain BTAD PF03704.17 KIR65831.1 - 1.7e-10 41.5 4.6 3.9e-10 40.4 4.6 1.6 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KIR65831.1 - 0.00084 19.4 1.4 0.0028 17.7 0.0 2.6 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal HTH_15 PF12324.8 KIR65831.1 - 0.026 14.5 0.2 11 6.1 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase PNP_UDP_1 PF01048.20 KIR65831.1 - 0.032 13.5 0.1 0.15 11.3 0.0 2.0 2 1 0 2 2 2 0 Phosphorylase superfamily TPR_14 PF13428.6 KIR65831.1 - 1.5 9.9 11.3 7.5 7.7 3.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Lentiviral_Tat PF02998.14 KIR65833.1 - 0.012 15.6 1.2 0.15 12.1 0.1 2.4 2 0 0 2 2 2 0 Lentiviral Tat protein HSP70 PF00012.20 KIR65834.1 - 1.6e-90 304.1 0.3 1.1e-67 228.7 0.0 3.0 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 KIR65834.1 - 4.1e-14 52.1 0.0 1.5e-13 50.3 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein HSCB_C PF07743.13 KIR65835.1 - 2 9.0 7.3 6.4 7.4 7.3 1.9 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF3487 PF11990.8 KIR65836.1 - 0.42 10.5 9.4 0.89 9.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Phage_holin_3_6 PF07332.11 KIR65836.1 - 2.6 8.1 22.6 0.57 10.2 5.6 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1232 PF06803.12 KIR65837.1 - 0.0013 18.4 7.0 0.0013 18.4 7.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1232) G3P_acyltransf PF02660.15 KIR65837.1 - 0.081 13.0 3.2 0.096 12.7 3.2 1.0 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase FUR PF01475.19 KIR65838.1 - 6.1e-21 74.8 0.0 6.8e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 KIR65838.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KIR65838.1 - 0.0006 19.7 1.7 0.0014 18.5 1.7 1.7 1 1 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR65838.1 - 0.016 15.2 0.7 0.055 13.5 0.3 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain TOBE_3 PF12857.7 KIR65838.1 - 0.025 14.5 0.1 0.069 13.1 0.1 1.7 2 0 0 2 2 2 0 TOBE-like domain Nudix_N_2 PF14803.6 KIR65838.1 - 0.052 13.5 1.3 0.052 13.5 1.3 2.6 2 0 0 2 2 2 0 Nudix N-terminal Penicillinase_R PF03965.16 KIR65838.1 - 0.057 13.8 0.0 0.064 13.6 0.0 1.1 1 0 0 1 1 1 0 Penicillinase repressor HTH_5 PF01022.20 KIR65838.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.8 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family Zn_ribbon_SprT PF17283.2 KIR65838.1 - 3.2 7.7 7.4 0.39 10.7 0.4 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain peroxidase PF00141.23 KIR65839.1 - 6e-86 287.9 0.0 4.5e-45 154.1 0.0 2.3 2 0 0 2 2 2 2 Peroxidase TROVE PF05731.11 KIR65840.1 - 1.4e-13 50.7 0.0 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 TROVE domain VWA_2 PF13519.6 KIR65840.1 - 0.00072 20.2 0.0 0.0018 18.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain PQQ_3 PF13570.6 KIR65840.1 - 0.013 16.0 2.4 0.1 13.1 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain Cupin_2 PF07883.11 KIR65841.1 - 6.1e-07 29.1 0.1 0.045 13.5 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_6 PF12852.7 KIR65841.1 - 0.0025 17.6 1.6 0.7 9.6 0.4 2.4 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.19 KIR65841.1 - 0.03 14.2 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain ADP_PFK_GK PF04587.15 KIR65842.1 - 6e-29 100.9 0.0 8.3e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region PfkB PF00294.24 KIR65842.1 - 1.1e-07 31.4 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase GST_C_2 PF13410.6 KIR65842.1 - 0.019 15.0 3.7 0.96 9.5 0.1 3.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain F_bP_aldolase PF01116.20 KIR65843.1 - 8.2e-89 297.8 0.0 9.2e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_1 PF01979.20 KIR65843.1 - 0.0049 16.2 0.1 0.055 12.8 0.1 2.1 1 1 1 2 2 2 1 Amidohydrolase family ThiG PF05690.14 KIR65843.1 - 0.087 12.1 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG BPD_transp_1 PF00528.22 KIR65844.1 - 7.1e-16 58.5 17.8 7.1e-16 58.5 17.8 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ATP1G1_PLM_MAT8 PF02038.16 KIR65844.1 - 0.021 14.2 0.5 0.39 10.2 0.1 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family BPD_transp_1 PF00528.22 KIR65845.1 - 1.3e-18 67.4 19.3 1.3e-18 67.4 19.3 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4357 PF14267.6 KIR65845.1 - 0.1 12.6 1.0 0.29 11.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) RskA PF10099.9 KIR65845.1 - 0.29 11.4 2.7 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SBP_bac_8 PF13416.6 KIR65846.1 - 2e-42 146.0 10.3 2.9e-42 145.4 10.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR65846.1 - 7.2e-35 121.4 10.9 1e-34 120.9 10.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR65846.1 - 1.4e-05 25.0 0.2 0.00033 20.5 0.2 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR65846.1 - 7.2e-05 22.3 0.8 0.062 12.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_3 PF00497.20 KIR65846.1 - 0.025 14.0 0.2 0.14 11.6 0.2 2.1 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF4328 PF14219.6 KIR65846.1 - 0.079 12.5 0.8 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) DeoRC PF00455.22 KIR65847.1 - 1.2e-41 142.4 0.3 1.9e-41 141.7 0.3 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 KIR65847.1 - 2.8e-18 65.4 0.2 6.7e-18 64.2 0.1 1.7 2 0 0 2 2 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KIR65847.1 - 7.4e-08 32.2 0.0 2e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 KIR65847.1 - 2e-06 27.4 0.1 4.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KIR65847.1 - 6.6e-05 22.7 0.4 0.00018 21.3 0.4 1.8 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR65847.1 - 0.00056 19.9 0.7 0.003 17.6 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR65847.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR65847.1 - 0.0026 17.1 0.2 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KIR65847.1 - 0.0027 17.8 0.1 0.0057 16.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 KIR65847.1 - 0.003 17.3 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein HTH_24 PF13412.6 KIR65847.1 - 0.0032 17.0 0.0 0.014 14.9 0.0 2.2 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding FeoC PF09012.10 KIR65847.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator FaeA PF04703.12 KIR65847.1 - 0.011 16.1 0.1 0.039 14.3 0.0 1.9 2 0 0 2 2 2 0 FaeA-like protein SpoIIID PF12116.8 KIR65847.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D MarR PF01047.22 KIR65847.1 - 0.017 15.1 0.0 0.057 13.3 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 KIR65847.1 - 0.019 14.7 0.1 0.06 13.2 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain EutK_C PF16365.5 KIR65847.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus EAP30 PF04157.16 KIR65847.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 EAP30/Vps36 family Rrf2 PF02082.20 KIR65847.1 - 0.056 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_29 PF13551.6 KIR65847.1 - 0.071 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix PaaX PF07848.12 KIR65847.1 - 0.094 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein LacI PF00356.21 KIR65847.1 - 0.098 12.5 0.1 23 4.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Sigma70_r4 PF04545.16 KIR65847.1 - 0.11 12.0 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_5 PF01022.20 KIR65847.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Aldo_ket_red PF00248.21 KIR65848.1 - 2.1e-21 76.4 0.0 1.2e-19 70.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HTH_Tnp_1 PF01527.20 KIR65848.1 - 0.088 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Transposase DUF1707 PF08044.11 KIR65848.1 - 0.12 12.5 8.3 0.85 9.7 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) adh_short PF00106.25 KIR65849.1 - 5.3e-24 84.8 0.0 2.2e-23 82.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR65849.1 - 3.9e-10 39.7 0.0 5.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR65849.1 - 1.5e-05 25.0 0.2 2.4e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR65849.1 - 8.1e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KIR65849.1 - 0.14 12.0 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF11 PF01345.18 KIR65850.1 - 3.9e-06 27.1 5.2 0.035 14.4 0.1 4.4 3 3 0 3 3 3 2 Domain of unknown function DUF11 Keratin_2_head PF16208.5 KIR65850.1 - 0.2 11.8 0.2 0.2 11.8 0.2 2.7 3 0 0 3 3 3 0 Keratin type II head Methyltransf_25 PF13649.6 KIR65851.1 - 3.5e-14 53.3 0.0 7.9e-14 52.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65851.1 - 7.7e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65851.1 - 2.3e-10 40.5 0.0 4.4e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR65851.1 - 1.9e-09 37.2 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIR65851.1 - 6.7e-07 29.3 0.0 3.3e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65851.1 - 1e-06 29.4 0.0 1.8e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR65851.1 - 0.00014 21.5 0.1 0.0027 17.3 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 KIR65851.1 - 0.0044 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KIR65851.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KIR65851.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KIR65851.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KIR65851.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 ArabFuran-catal PF09206.11 KIR65852.1 - 6.2e-155 515.3 9.2 9.1e-155 514.7 9.2 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CBM_2 PF00553.19 KIR65852.1 - 6.1e-34 116.4 11.2 6.1e-34 116.4 11.2 1.9 2 0 0 2 2 2 1 Cellulose binding domain Alpha_L_fucos PF01120.17 KIR65853.1 - 3e-87 293.3 6.2 3.8e-87 293.0 6.2 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase CBM_2 PF00553.19 KIR65853.1 - 3.3e-26 91.5 15.3 1.4e-25 89.5 15.3 2.2 1 0 0 1 1 1 1 Cellulose binding domain Fucosidase_C PF16757.5 KIR65853.1 - 3e-07 30.9 0.0 1e-06 29.2 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain Rhodanese PF00581.20 KIR65854.1 - 8.4e-21 74.5 0.0 5.9e-12 46.1 0.0 2.8 3 0 0 3 3 3 2 Rhodanese-like domain Lactamase_B PF00753.27 KIR65854.1 - 5.8e-09 36.2 6.3 8.4e-08 32.4 6.3 2.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR65854.1 - 0.015 14.8 0.5 0.21 11.1 0.2 2.7 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Rhodanese PF00581.20 KIR65855.1 - 1.7e-11 44.6 0.0 7.2e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 KIR65855.1 - 1.2e-05 25.5 9.8 3.4e-05 23.9 9.8 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4350 PF14258.6 KIR65855.1 - 0.081 13.4 3.0 7.2 7.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Rhodanese PF00581.20 KIR65856.1 - 5e-17 62.4 0.0 6.7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF2892 PF11127.8 KIR65856.1 - 5e-11 42.5 3.8 1.1e-10 41.4 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) TauE PF01925.19 KIR65857.1 - 1.9e-54 184.8 48.6 1.9e-54 184.8 48.6 1.8 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DUF3784 PF12650.7 KIR65857.1 - 0.76 10.0 0.1 0.76 10.0 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Pyr_redox_2 PF07992.14 KIR65858.1 - 7.3e-32 110.8 0.5 3.7e-31 108.5 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR65858.1 - 1.8e-15 57.0 0.2 2.1e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Response_reg PF00072.24 KIR65858.1 - 9.3e-12 45.1 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox PF00070.27 KIR65858.1 - 4.6e-08 33.5 0.8 0.00036 21.0 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR65858.1 - 1.3e-07 31.5 11.4 0.00019 21.2 11.4 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIR65858.1 - 1.8e-07 30.8 4.9 6.4e-07 29.1 1.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR65858.1 - 2.7e-05 23.1 0.6 0.0041 15.9 1.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KIR65858.1 - 2.7e-05 23.6 3.5 0.00028 20.3 0.9 2.4 2 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIR65858.1 - 4.7e-05 22.7 3.3 0.00037 19.8 0.5 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KIR65858.1 - 0.00019 20.6 2.5 0.0035 16.5 1.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIR65858.1 - 0.00052 20.2 5.6 0.0036 17.5 1.3 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR65858.1 - 0.0007 18.8 4.0 0.0007 18.8 4.0 2.8 2 1 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 KIR65858.1 - 0.0079 16.2 5.7 0.022 14.7 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIR65858.1 - 0.02 14.1 0.1 5.2 6.1 0.0 2.7 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KIR65858.1 - 0.064 12.3 2.9 0.42 9.6 1.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HATPase_c PF02518.26 KIR65859.1 - 2.6e-21 76.2 0.0 4.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase cNMP_binding PF00027.29 KIR65859.1 - 2.7e-10 40.2 0.1 7.3e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HisKA PF00512.25 KIR65859.1 - 0.00037 20.5 1.7 0.0028 17.7 0.5 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Ish1 PF10281.9 KIR65859.1 - 0.02 15.2 0.0 0.33 11.3 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein HATPase_c_5 PF14501.6 KIR65859.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.5 1 1 0 1 1 1 0 GHKL domain DUF2771 PF10969.8 KIR65860.1 - 0.17 12.0 0.5 0.18 11.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) APH PF01636.23 KIR65861.1 - 5.7e-18 65.7 12.1 9.5e-18 65.0 12.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KIR65861.1 - 0.034 13.4 0.0 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase GDP_Man_Dehyd PF16363.5 KIR65862.1 - 2.3e-72 244.2 0.0 4.7e-72 243.2 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIR65862.1 - 2.3e-59 200.8 0.0 2.8e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR65862.1 - 5.7e-15 55.1 0.0 7.3e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIR65862.1 - 5.9e-14 51.8 0.0 7.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIR65862.1 - 1.2e-13 50.8 0.1 6.6e-12 45.1 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KIR65862.1 - 9e-10 38.2 0.0 2e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KIR65862.1 - 2.4e-05 24.3 0.0 3.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KIR65862.1 - 0.0091 15.5 0.3 2.7 7.4 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase Methyltransf_15 PF09445.10 KIR65862.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NmrA PF05368.13 KIR65862.1 - 0.22 11.0 0.0 0.44 10.1 0.0 1.4 2 0 0 2 2 2 0 NmrA-like family ABC_tran PF00005.27 KIR65863.1 - 1.9e-24 86.7 0.0 2.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65863.1 - 3.7e-13 49.9 0.0 9.8e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KIR65863.1 - 7.4e-09 36.2 0.0 1.4e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) KdpD PF02702.17 KIR65863.1 - 0.0014 18.2 0.0 0.0082 15.6 0.0 1.9 1 1 1 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain AAA_18 PF13238.6 KIR65863.1 - 0.0026 18.3 0.7 0.012 16.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR65863.1 - 0.0087 16.5 2.8 0.014 15.8 0.3 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KIR65863.1 - 0.024 14.4 1.4 0.041 13.6 0.1 2.1 2 2 1 3 3 3 0 AAA domain AAA_23 PF13476.6 KIR65863.1 - 0.024 15.1 0.0 0.034 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain BCA_ABC_TP_C PF12399.8 KIR65863.1 - 0.027 14.4 0.0 0.088 12.8 0.0 2.0 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter AAA_22 PF13401.6 KIR65863.1 - 0.031 14.6 0.0 0.23 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIR65863.1 - 0.035 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 KIR65863.1 - 0.057 13.1 0.0 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KIR65863.1 - 0.069 13.6 0.0 0.46 10.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ACT PF01842.25 KIR65863.1 - 0.072 12.9 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 ACT domain SbcCD_C PF13558.6 KIR65863.1 - 0.077 13.2 0.0 0.98 9.7 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIR65863.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KIR65863.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain CbiA PF01656.23 KIR65863.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNF2_N PF00176.23 KIR65864.1 - 2.3e-48 164.7 0.0 4.1e-48 163.9 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF3670 PF12419.8 KIR65864.1 - 1.1e-22 80.4 2.9 1.1e-22 80.4 2.9 2.2 2 1 0 2 2 2 1 SNF2 Helicase protein Helicase_C PF00271.31 KIR65864.1 - 2.3e-19 69.8 0.0 4.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR65864.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_31 PF13560.6 KIR65865.1 - 1.6e-10 41.2 0.3 1.6e-10 41.2 0.3 4.5 5 1 0 5 5 5 2 Helix-turn-helix domain HTH_3 PF01381.22 KIR65865.1 - 0.00016 21.6 0.0 0.00053 20.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR65865.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DEAD PF00270.29 KIR65865.1 - 0.049 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase KorB PF08535.10 KIR65865.1 - 0.16 12.0 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 KorB domain Bim_N PF06773.11 KIR65866.1 - 0.2 11.4 3.0 0.25 11.1 2.7 1.4 1 1 0 1 1 1 0 Bim protein N-terminus GntR PF00392.21 KIR65867.1 - 1e-15 57.1 0.0 1.2e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 KIR65867.1 - 0.00017 21.4 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.20 KIR65867.1 - 0.00097 19.4 0.0 0.0012 19.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 KIR65867.1 - 0.0053 16.6 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 KIR65867.1 - 0.0087 16.0 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KIR65867.1 - 0.013 15.7 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 KIR65867.1 - 0.024 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KIR65867.1 - 0.027 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 KIR65867.1 - 0.04 13.6 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 KIR65867.1 - 0.045 13.7 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 MarR family RepL PF05732.11 KIR65867.1 - 0.092 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) GntR PF00392.21 KIR65868.1 - 5.7e-16 57.9 0.1 6.3e-16 57.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 KIR65868.1 - 8e-05 22.3 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.16 KIR65868.1 - 0.0066 16.2 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Crp_2 PF13545.6 KIR65868.1 - 0.0076 16.2 0.2 0.048 13.6 0.1 1.9 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_36 PF13730.6 KIR65868.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR65868.1 - 0.023 14.5 0.1 0.064 13.1 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 KIR65868.1 - 0.027 14.4 0.1 0.055 13.4 0.1 1.6 2 0 0 2 2 2 0 HTH domain TetR_C_1 PF02909.17 KIR65869.1 - 5e-21 75.0 0.0 6.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65869.1 - 1.7e-07 30.9 0.0 5.4e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Trypsin PF00089.26 KIR65870.1 - 9.6e-07 28.8 7.2 3.1e-06 27.1 7.2 1.8 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KIR65870.1 - 0.00016 22.6 10.1 0.0022 18.9 10.1 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain Pro_Al_protease PF02983.14 KIR65870.1 - 0.0044 17.0 6.6 0.0044 17.0 6.6 2.6 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Herpes_UL32 PF06070.11 KIR65870.1 - 5.8 4.5 5.5 9 3.9 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 MEDS PF14417.6 KIR65871.1 - 2.2e-24 86.1 0.0 3.5e-23 82.2 0.0 2.3 2 1 0 2 2 2 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HATPase_c_2 PF13581.6 KIR65871.1 - 9.7e-14 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain FMN_red PF03358.15 KIR65872.1 - 3.8e-37 127.4 0.1 5.3e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIR65872.1 - 7.6e-11 42.1 0.0 1.2e-10 41.5 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold ROK PF00480.20 KIR65873.1 - 1.6e-36 126.3 0.0 1.1e-35 123.5 0.0 1.9 1 1 0 1 1 1 1 ROK family Attacin_N PF03768.15 KIR65873.1 - 0.28 11.3 3.1 20 5.4 0.2 2.7 2 0 0 2 2 2 0 Attacin, N-terminal region DoxX_2 PF13564.6 KIR65874.1 - 3.7e-20 72.0 14.9 4.3e-20 71.7 14.9 1.1 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 KIR65874.1 - 3.7e-06 27.4 9.3 3.7e-06 27.4 9.3 1.9 2 0 0 2 2 2 1 DoxX DUF3742 PF12553.8 KIR65874.1 - 0.059 13.5 3.3 0.097 12.8 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3742) DHquinase_II PF01220.19 KIR65875.1 - 1.6e-44 150.9 0.0 1.8e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II DUF727 PF05303.12 KIR65875.1 - 0.25 11.4 0.0 0.38 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF727) DegT_DnrJ_EryC1 PF01041.17 KIR65876.1 - 2.3e-114 382.5 0.0 2.8e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIR65876.1 - 1.9e-08 33.9 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR65876.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GFO_IDH_MocA PF01408.22 KIR65877.1 - 7.3e-23 81.7 0.1 1.3e-22 80.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR65877.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KIR65877.1 - 8.1e-06 26.3 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 KIR65877.1 - 0.028 15.1 0.0 0.19 12.4 0.0 2.3 3 0 0 3 3 3 0 CoA binding domain HAD_2 PF13419.6 KIR65878.1 - 3e-31 108.9 0.0 3.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR65878.1 - 1.2e-20 74.8 0.0 6.5e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR65878.1 - 4.2e-08 33.8 0.1 1e-07 32.6 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR65878.1 - 6.6e-08 32.5 0.4 1.2e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIR65878.1 - 0.00088 19.4 0.0 0.073 13.2 0.0 2.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR65878.1 - 0.053 13.3 0.0 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KIR65878.1 - 0.13 12.1 0.0 0.55 10.1 0.0 1.9 1 1 0 1 1 1 0 Acid Phosphatase Methyltransf_25 PF13649.6 KIR65879.1 - 1.7e-12 47.9 0.0 3.7e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65879.1 - 3.5e-11 43.6 0.3 8.2e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR65879.1 - 1.7e-09 37.7 0.0 3.3e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65879.1 - 1.8e-05 25.4 0.0 4.4e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65879.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KIR65879.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DHQ_synthase PF01761.20 KIR65881.1 - 5.2e-80 268.4 0.2 3.6e-79 265.6 0.2 1.9 1 1 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KIR65881.1 - 2.2e-07 30.9 0.1 6.3e-06 26.1 0.1 2.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 KIR65881.1 - 2.5e-05 23.2 5.4 0.00042 19.2 5.4 2.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase ketoacyl-synt PF00109.26 KIR65882.1 - 1.2e-175 582.0 15.3 5.4e-89 298.1 0.5 3.8 4 0 0 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65882.1 - 8.1e-151 502.0 7.2 3.2e-94 316.0 1.0 2.5 2 0 0 2 2 2 2 Acyl transferase domain KR PF08659.10 KIR65882.1 - 4.6e-114 378.6 29.0 4e-54 183.3 0.3 5.7 4 1 0 4 4 4 3 KR domain AMP-binding PF00501.28 KIR65882.1 - 5.3e-101 338.3 0.0 1e-100 337.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.22 KIR65882.1 - 6.2e-88 290.7 5.9 3.7e-43 146.3 0.5 3.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR65882.1 - 5e-68 229.5 39.4 8e-52 176.3 6.9 5.2 5 1 0 5 5 5 2 Polyketide synthase dehydratase PP-binding PF00550.25 KIR65882.1 - 2.1e-36 124.1 0.0 5.9e-12 45.8 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KIR65882.1 - 2.4e-28 98.8 0.0 2.9e-13 50.3 0.0 3.1 4 0 0 4 4 2 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KIR65882.1 - 1.2e-20 73.8 16.2 1.8e-12 47.2 0.8 4.7 5 0 0 5 5 5 2 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KIR65882.1 - 5.2e-20 72.9 1.9 1.7e-19 71.2 0.1 3.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 KIR65882.1 - 8.8e-18 64.6 1.5 8.4e-08 31.9 0.1 3.1 3 0 0 3 3 3 2 Thiolase, N-terminal domain AMP-binding_C PF13193.6 KIR65882.1 - 1.9e-16 60.8 0.1 1.9e-16 60.8 0.1 4.8 2 1 1 3 3 2 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 KIR65882.1 - 8.8e-15 54.8 0.4 1e-12 48.2 0.0 4.4 5 0 0 5 5 3 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KIR65882.1 - 6.2e-11 42.2 7.4 2.7e-07 30.3 0.7 3.2 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65882.1 - 4.4e-08 32.9 0.2 0.00011 21.7 0.1 2.7 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIR65882.1 - 1.8e-06 27.3 0.0 9.3e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ADH_N PF08240.12 KIR65882.1 - 2e-05 24.4 0.1 7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 KIR65882.1 - 0.00069 19.9 7.9 0.0012 19.1 0.5 3.9 4 0 0 4 4 3 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KIR65882.1 - 0.00089 18.3 0.0 0.0031 16.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Erythro-docking PF09277.11 KIR65882.1 - 0.0052 16.7 0.4 0.035 14.0 0.4 2.6 1 0 0 1 1 1 1 Erythronolide synthase, docking NmrA PF05368.13 KIR65882.1 - 0.03 13.9 8.9 0.29 10.7 1.9 2.9 3 0 0 3 3 3 0 NmrA-like family ACP_syn_III PF08545.10 KIR65882.1 - 0.14 12.0 8.5 0.88 9.5 0.3 4.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 KIR65882.1 - 0.29 10.8 11.0 0.43 10.3 2.9 3.5 2 1 1 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis NAD_binding_4 PF07993.12 KIR65882.1 - 2.3 7.3 6.7 6.2 5.9 1.2 2.7 2 1 0 2 2 2 0 Male sterility protein FAD_binding_3 PF01494.19 KIR65883.1 - 9e-60 202.8 0.0 1.2e-59 202.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR65883.1 - 0.00058 19.5 0.5 0.22 11.1 0.1 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR65883.1 - 0.004 16.4 0.1 0.21 10.8 0.1 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIR65883.1 - 0.0041 16.4 0.0 0.093 12.0 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KIR65883.1 - 0.0062 15.7 0.0 0.05 12.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KIR65883.1 - 0.013 14.3 0.3 0.87 8.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KIR65883.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIR65883.1 - 0.065 12.6 0.0 0.18 11.1 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR65883.1 - 0.089 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KIR65883.1 - 0.2 11.2 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KIR65884.1 - 2.8e-19 69.6 0.0 6.7e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65884.1 - 5.4e-19 68.6 0.0 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65884.1 - 7.7e-16 58.2 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIR65884.1 - 2.4e-13 50.0 0.0 3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KIR65884.1 - 7.2e-13 48.4 0.0 1.4e-12 47.5 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KIR65884.1 - 1.4e-07 32.2 0.0 2.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR65884.1 - 8.7e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR65884.1 - 9.5e-05 22.0 0.0 0.00021 20.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 KIR65884.1 - 0.00085 19.1 0.0 0.0026 17.4 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KIR65884.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIR65884.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIR65884.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KIR65884.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase Thioesterase PF00975.20 KIR65885.1 - 2.2e-53 181.8 0.0 2.4e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KIR65885.1 - 2e-09 38.4 6.9 2.8e-09 37.9 6.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR65885.1 - 3e-05 23.8 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR65885.1 - 0.014 14.7 0.0 0.074 12.3 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KIR65885.1 - 0.07 12.7 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 KIR65885.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 KIR65886.1 - 7.1e-87 291.2 2.4 8.1e-87 291.0 0.6 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KIR65886.1 - 2e-58 197.3 0.7 1e-57 195.0 0.9 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KIR65886.1 - 3.6e-58 197.6 0.2 5.8e-58 196.9 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KIR65886.1 - 1.7e-54 185.1 9.2 4e-54 183.9 9.2 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KIR65886.1 - 7.4e-45 151.8 0.6 1.8e-44 150.6 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR65886.1 - 8.7e-16 58.4 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65886.1 - 7.6e-14 51.8 0.0 2.9e-13 50.0 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Docking PF08990.11 KIR65886.1 - 5.1e-11 42.0 12.5 5.1e-11 42.0 12.5 2.5 2 0 0 2 2 2 1 Erythronolide synthase docking adh_short PF00106.25 KIR65886.1 - 5.3e-11 42.3 0.1 1.3e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KIR65886.1 - 1.5e-08 34.3 0.1 6.2e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KIR65886.1 - 5.8e-07 29.3 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIR65886.1 - 0.00029 20.4 0.1 0.00049 19.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACP_syn_III PF08545.10 KIR65886.1 - 0.0041 16.9 0.8 0.016 15.0 0.8 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 KIR65886.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIR65886.1 - 0.04 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.26 KIR65887.1 - 2.9e-264 872.4 23.1 1.2e-89 300.2 1.1 5.1 5 0 0 5 5 5 3 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65887.1 - 8.7e-177 587.3 6.7 4.5e-59 200.5 0.1 3.4 3 0 0 3 3 3 3 Acyl transferase domain KR PF08659.10 KIR65887.1 - 1.1e-168 556.6 21.2 1e-56 191.7 1.4 4.6 4 0 0 4 4 4 3 KR domain Ketoacyl-synt_C PF02801.22 KIR65887.1 - 3.4e-137 449.6 14.4 4.1e-45 152.6 1.1 4.5 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR65887.1 - 5.5e-46 155.6 0.0 6.1e-15 55.6 0.0 3.5 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KIR65887.1 - 1.7e-40 138.5 7.9 9.4e-14 51.3 0.8 3.8 3 0 0 3 3 3 3 short chain dehydrogenase PP-binding PF00550.25 KIR65887.1 - 6.4e-40 135.4 0.4 5.7e-12 45.8 0.0 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site Thiolase_N PF00108.23 KIR65887.1 - 4.7e-27 95.0 3.9 3.8e-08 33.0 0.2 4.6 4 0 0 4 4 4 3 Thiolase, N-terminal domain PKS_DE PF18369.1 KIR65887.1 - 1.3e-21 76.9 22.0 8.1e-13 48.7 6.3 8.3 7 0 0 7 7 4 2 Polyketide synthase dimerisation element domain adh_short_C2 PF13561.6 KIR65887.1 - 2.8e-21 76.2 17.1 2.1e-07 30.8 1.9 4.2 4 0 0 4 4 4 3 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIR65887.1 - 9.8e-15 54.7 8.0 6.9e-07 29.0 0.1 3.4 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIR65887.1 - 2e-14 53.4 0.0 0.0021 17.3 0.0 3.2 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIR65887.1 - 5.9e-12 45.6 0.0 0.01 15.3 0.0 3.2 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase Docking PF08990.11 KIR65887.1 - 3.4e-09 36.2 2.6 9.9e-09 34.7 2.6 1.9 1 0 0 1 1 1 1 Erythronolide synthase docking NmrA PF05368.13 KIR65887.1 - 2.1e-06 27.5 13.8 0.017 14.7 0.5 3.6 3 0 0 3 3 3 3 NmrA-like family ACP_syn_III PF08545.10 KIR65887.1 - 5.8e-06 26.1 7.5 0.95 9.4 0.2 4.1 3 0 0 3 3 3 3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 2-Hacid_dh_C PF02826.19 KIR65887.1 - 4.2e-05 23.0 4.0 1 8.7 0.1 3.7 3 0 0 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KIR65887.1 - 0.01 15.0 14.0 0.13 11.3 1.5 3.4 3 0 0 3 3 3 0 RmlD substrate binding domain SAT PF16073.5 KIR65887.1 - 0.34 10.6 9.9 63 3.2 0.0 6.1 7 0 0 7 7 7 0 Starter unit:ACP transacylase in aflatoxin biosynthesis F420_oxidored PF03807.17 KIR65887.1 - 0.69 10.5 7.2 4.4 8.0 0.1 3.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Metallophos PF00149.28 KIR65888.1 - 2.5e-16 60.8 0.2 3.3e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIR65888.1 - 1.2e-05 25.5 0.0 0.0076 16.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Plant_tran PF04827.14 KIR65888.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein ketoacyl-synt PF00109.26 KIR65889.1 - 0 1189.0 31.3 5.2e-92 308.0 1.0 7.2 8 0 0 8 8 8 4 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65889.1 - 7.9e-247 817.4 9.9 6.2e-83 278.9 0.0 4.6 4 0 0 4 4 4 4 Acyl transferase domain KR PF08659.10 KIR65889.1 - 1.8e-225 741.5 38.7 3e-58 196.7 4.5 5.3 4 0 0 4 4 4 4 KR domain Ketoacyl-synt_C PF02801.22 KIR65889.1 - 7.9e-184 600.1 19.2 1.4e-45 154.1 0.8 5.2 5 0 0 5 5 5 4 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR65889.1 - 4.9e-164 544.7 36.0 1.2e-55 188.8 6.4 4.0 3 0 0 3 3 3 3 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIR65889.1 - 2.8e-62 208.1 0.0 1.3e-15 57.8 0.0 4.6 4 0 0 4 4 4 4 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KIR65889.1 - 2.8e-60 203.2 13.7 2.3e-19 70.8 0.1 6.1 5 0 0 5 5 4 3 Zinc-binding dehydrogenase PP-binding PF00550.25 KIR65889.1 - 5e-49 164.5 0.0 1.4e-11 44.6 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 KIR65889.1 - 5.1e-39 133.2 13.3 5.5e-12 45.8 0.2 6.1 4 0 0 4 4 4 3 Zinc-binding dehydrogenase adh_short PF00106.25 KIR65889.1 - 1.5e-37 128.9 29.1 1.7e-10 40.6 0.1 5.3 5 0 0 5 5 5 4 short chain dehydrogenase Thiolase_N PF00108.23 KIR65889.1 - 4.1e-33 114.9 10.1 1.4e-08 34.5 0.2 5.6 5 0 0 5 5 5 4 Thiolase, N-terminal domain ADH_N PF08240.12 KIR65889.1 - 2.4e-26 91.8 4.6 1.1e-07 31.7 0.0 4.5 5 0 0 5 5 3 3 Alcohol dehydrogenase GroES-like domain PKS_DE PF18369.1 KIR65889.1 - 6.4e-13 49.0 7.3 6.4e-13 49.0 7.3 7.3 10 0 0 10 10 3 1 Polyketide synthase dimerisation element domain Docking PF08990.11 KIR65889.1 - 3.7e-10 39.2 5.6 1.3e-09 37.5 5.6 2.1 1 0 0 1 1 1 1 Erythronolide synthase docking Epimerase PF01370.21 KIR65889.1 - 2.6e-08 33.6 18.2 0.00015 21.3 0.3 4.6 4 0 0 4 4 4 4 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIR65889.1 - 9.7e-05 21.6 2.0 0.005 16.0 0.0 3.4 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIR65889.1 - 0.00013 21.5 0.1 0.0093 15.4 0.0 3.2 4 0 0 4 4 4 1 GDP-mannose 4,6 dehydratase Thiolase_C PF02803.18 KIR65889.1 - 0.0082 15.8 0.0 6.6 6.4 0.0 4.9 5 0 0 5 5 5 1 Thiolase, C-terminal domain NmrA PF05368.13 KIR65889.1 - 0.017 14.7 26.3 0.053 13.1 0.2 4.7 4 0 0 4 4 4 0 NmrA-like family AlaDh_PNT_C PF01262.21 KIR65889.1 - 0.082 12.2 12.6 6.3 6.0 0.4 4.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FA_desaturase PF00487.24 KIR65889.1 - 0.23 11.3 7.7 8.2 6.2 0.2 3.4 3 0 0 3 3 3 0 Fatty acid desaturase DUF4232 PF14016.6 KIR65889.1 - 0.37 10.9 31.2 0.83 9.8 4.2 5.9 4 0 0 4 4 3 0 Protein of unknown function (DUF4232) RmlD_sub_bind PF04321.17 KIR65889.1 - 0.45 9.6 13.2 0.13 11.3 0.3 4.0 4 0 0 4 4 4 0 RmlD substrate binding domain Rhomboid PF01694.22 KIR65889.1 - 3.2 7.7 11.1 32 4.5 0.2 3.7 3 0 0 3 3 3 0 Rhomboid family ACP_syn_III PF08545.10 KIR65889.1 - 3.5 7.6 34.2 0.88 9.5 0.4 6.6 7 0 0 7 7 6 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KIR65890.1 - 0 1833.9 50.3 1.7e-94 316.1 0.5 9.8 12 0 0 12 12 12 6 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65890.1 - 0 1131.1 44.4 2.6e-71 240.8 2.1 6.5 6 0 0 6 6 6 6 Acyl transferase domain KR PF08659.10 KIR65890.1 - 6.1e-295 967.9 62.4 3.4e-61 206.3 2.3 8.1 6 1 1 7 7 7 6 KR domain Ketoacyl-synt_C PF02801.22 KIR65890.1 - 4.3e-273 888.0 36.6 7.6e-46 155.0 0.8 7.0 6 0 0 6 6 6 6 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR65890.1 - 7.9e-154 511.2 30.0 9.4e-55 185.9 2.8 3.9 3 0 0 3 3 3 3 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIR65890.1 - 1.4e-86 286.3 0.0 1.5e-15 57.6 0.0 6.6 6 0 0 6 6 6 6 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65890.1 - 3.7e-80 264.2 0.7 9.1e-12 45.2 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site adh_short PF00106.25 KIR65890.1 - 3.8e-60 202.7 33.8 3e-14 52.9 1.8 6.2 6 0 0 6 6 6 5 short chain dehydrogenase Thiolase_N PF00108.23 KIR65890.1 - 7.9e-54 182.7 17.6 6.6e-08 32.2 0.1 8.1 7 0 0 7 7 7 6 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KIR65890.1 - 9.2e-41 139.9 37.5 1.6e-09 37.7 0.1 6.2 6 0 0 6 6 6 5 Enoyl-(Acyl carrier protein) reductase PKS_DE PF18369.1 KIR65890.1 - 7.3e-28 96.9 58.8 5.6e-13 49.2 6.3 9.4 7 0 0 7 7 3 3 Polyketide synthase dimerisation element domain Epimerase PF01370.21 KIR65890.1 - 6.2e-24 84.8 27.6 8.9e-11 41.7 0.6 6.2 6 0 0 6 6 6 5 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65890.1 - 4.4e-22 78.9 5.6 1.3e-05 24.8 0.0 6.2 6 0 0 6 6 6 5 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIR65890.1 - 3.9e-16 59.0 3.4 0.00027 20.2 0.0 5.2 5 0 0 5 5 5 4 Polysaccharide biosynthesis protein PikAIV_N PF18605.1 KIR65890.1 - 1.2e-12 47.2 3.6 1.2e-12 47.2 3.6 4.5 4 0 0 4 4 3 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ACP_syn_III PF08545.10 KIR65890.1 - 1.1e-09 38.0 25.4 0.41 10.5 0.2 7.6 6 0 0 6 6 6 5 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 KIR65890.1 - 2.9e-07 30.5 2.1 1.7 8.3 0.0 7.3 6 1 0 7 7 7 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_C PF02803.18 KIR65890.1 - 0.0016 18.1 0.0 27 4.5 0.0 5.8 6 0 0 6 6 6 0 Thiolase, C-terminal domain RVT_3 PF13456.6 KIR65890.1 - 0.022 14.6 0.0 44 3.9 0.0 4.9 5 0 0 5 5 5 0 Reverse transcriptase-like NmrA PF05368.13 KIR65890.1 - 0.026 14.1 35.9 0.0075 15.8 1.9 5.6 5 0 0 5 5 5 0 NmrA-like family NAD_binding_4 PF07993.12 KIR65890.1 - 0.047 12.8 15.1 6.8 5.8 0.2 4.8 5 0 0 5 5 5 0 Male sterility protein HTH_31 PF13560.6 KIR65893.1 - 1.3e-11 44.7 4.5 1.3e-11 44.7 4.5 4.3 4 2 0 4 4 4 2 Helix-turn-helix domain HTH_3 PF01381.22 KIR65893.1 - 8.4e-06 25.8 0.0 2.6e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR65893.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain ketoacyl-synt PF00109.26 KIR65894.1 - 2.4e-175 581.0 13.8 6.8e-91 304.3 0.2 3.8 5 0 0 5 5 5 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65894.1 - 5e-138 460.0 6.0 8.4e-80 268.6 0.7 2.8 2 0 0 2 2 2 2 Acyl transferase domain KR PF08659.10 KIR65894.1 - 7.5e-109 361.6 6.2 2.8e-58 196.8 0.2 3.5 3 0 0 3 3 2 2 KR domain Ketoacyl-synt_C PF02801.22 KIR65894.1 - 1e-88 293.3 11.8 1.7e-44 150.6 0.6 3.3 3 0 0 3 3 2 2 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR65894.1 - 8.1e-44 150.0 5.5 1.9e-43 148.8 5.5 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIR65894.1 - 8.7e-33 113.1 0.0 2.5e-17 63.3 0.0 2.6 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65894.1 - 3.9e-26 91.2 0.1 5.8e-12 45.8 0.0 3.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 KIR65894.1 - 1.5e-19 70.2 0.0 2.6e-08 33.5 0.0 3.4 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 KIR65894.1 - 2.3e-15 56.7 0.6 8.9e-09 35.2 0.1 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KIR65894.1 - 3.1e-12 46.4 8.5 3e-06 26.8 0.1 3.6 3 0 0 3 3 3 2 Thiolase, N-terminal domain PKS_DE PF18369.1 KIR65894.1 - 8.4e-12 45.5 6.9 8.4e-12 45.5 6.9 5.2 4 0 0 4 4 1 1 Polyketide synthase dimerisation element domain Docking PF08990.11 KIR65894.1 - 3.9e-11 42.4 1.3 3.9e-11 42.4 1.3 2.2 2 0 0 2 2 1 1 Erythronolide synthase docking Polysacc_synt_2 PF02719.15 KIR65894.1 - 5.1e-08 32.4 0.0 0.00062 19.0 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIR65894.1 - 9.1e-08 31.9 0.0 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIR65894.1 - 6.4e-05 22.6 4.0 0.027 14.0 0.5 2.4 2 0 0 2 2 2 2 NmrA-like family ACP_syn_III PF08545.10 KIR65894.1 - 0.0013 18.6 3.0 0.33 10.8 0.3 3.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_10 PF13460.6 KIR65894.1 - 0.0038 17.1 1.4 0.0038 17.1 1.4 6.9 8 0 0 8 8 8 2 NAD(P)H-binding Shikimate_DH PF01488.20 KIR65894.1 - 0.023 14.8 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KIR65894.1 - 0.05 12.6 0.1 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family SAT PF16073.5 KIR65894.1 - 0.19 11.4 11.0 0.77 9.4 2.1 3.7 2 2 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis RmlD_sub_bind PF04321.17 KIR65894.1 - 0.22 10.6 6.4 0.32 10.0 0.1 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIR65894.1 - 0.48 9.6 3.7 8.2 5.5 0.1 2.4 2 0 0 2 2 2 0 Male sterility protein ketoacyl-synt PF00109.26 KIR65895.1 - 9.2e-279 919.8 13.2 1.3e-95 319.8 0.1 5.7 7 0 0 7 7 7 3 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65895.1 - 7.8e-194 643.3 8.1 6.4e-87 292.0 0.1 3.7 3 0 0 3 3 3 3 Acyl transferase domain KR PF08659.10 KIR65895.1 - 1.2e-161 533.5 25.4 2.5e-57 193.7 2.4 4.8 4 0 0 4 4 4 3 KR domain Ketoacyl-synt_C PF02801.22 KIR65895.1 - 2.7e-135 443.5 10.1 1.6e-45 153.9 0.2 4.1 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR65895.1 - 5.1e-56 190.1 9.3 5.1e-56 190.1 9.3 2.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIR65895.1 - 1.8e-50 170.1 0.0 5.7e-17 62.2 0.0 3.6 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65895.1 - 8.2e-38 128.6 0.0 5.4e-12 45.9 0.0 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site adh_short PF00106.25 KIR65895.1 - 3.7e-34 117.9 15.9 2.7e-13 49.8 0.7 4.0 4 0 0 4 4 4 3 short chain dehydrogenase Thiolase_N PF00108.23 KIR65895.1 - 2.3e-24 86.2 4.2 6.4e-08 32.3 0.1 3.8 3 0 0 3 3 3 3 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KIR65895.1 - 1.4e-22 80.5 17.8 8e-10 38.7 2.7 3.9 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase PKS_DE PF18369.1 KIR65895.1 - 3.3e-20 72.4 19.1 1.9e-12 47.5 7.7 8.7 8 0 0 8 8 5 2 Polyketide synthase dimerisation element domain Epimerase PF01370.21 KIR65895.1 - 1.4e-16 60.7 10.3 1.5e-05 24.6 0.7 3.4 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65895.1 - 6.5e-15 55.4 0.0 0.00022 20.8 0.0 3.2 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIR65895.1 - 1.2e-13 50.8 0.0 5.6e-05 22.4 0.0 3.2 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein Docking PF08990.11 KIR65895.1 - 1.3e-08 34.3 4.2 1.3e-08 34.3 4.2 2.3 2 0 0 2 2 1 1 Erythronolide synthase docking Sacchrp_dh_NADP PF03435.18 KIR65895.1 - 0.00012 22.4 8.5 0.097 12.9 0.2 3.8 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain SAT PF16073.5 KIR65895.1 - 0.003 17.3 14.4 2.5 7.7 0.5 5.8 4 2 0 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis NmrA PF05368.13 KIR65895.1 - 0.026 14.1 13.5 2.2 7.8 1.1 3.7 3 0 0 3 3 3 0 NmrA-like family ACP_syn_III PF08545.10 KIR65895.1 - 0.26 11.2 16.7 0.47 10.3 0.2 5.4 5 0 0 5 5 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GBP_PSP PF02425.15 KIR65895.1 - 0.73 9.5 3.6 87 2.9 0.1 3.6 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide RmlD_sub_bind PF04321.17 KIR65895.1 - 2.8 7.0 11.5 2.8 7.0 2.3 3.7 4 0 0 4 4 4 0 RmlD substrate binding domain ketoacyl-synt PF00109.26 KIR65896.1 - 7.6e-181 599.0 15.6 1.6e-93 313.0 3.2 3.5 4 0 0 4 4 3 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65896.1 - 3.7e-140 467.0 10.3 2.6e-79 267.0 0.4 2.7 2 0 0 2 2 2 2 Acyl transferase domain KR PF08659.10 KIR65896.1 - 3.6e-117 388.7 11.8 1.4e-59 201.1 2.9 3.2 3 0 0 3 3 2 2 KR domain Ketoacyl-synt_C PF02801.22 KIR65896.1 - 2.1e-86 285.8 14.3 4.2e-44 149.3 1.7 3.4 3 0 0 3 3 2 2 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KIR65896.1 - 1.6e-56 191.8 3.8 3.5e-56 190.6 3.8 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KIR65896.1 - 8.6e-33 113.1 0.0 3.1e-16 59.8 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65896.1 - 7.9e-27 93.4 0.1 1.3e-12 47.9 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 KIR65896.1 - 4.6e-23 81.7 10.8 2.1e-15 56.7 0.5 3.8 5 0 0 5 5 3 2 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KIR65896.1 - 7.2e-20 72.4 3.9 9.9e-19 68.7 0.1 4.2 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR65896.1 - 9.7e-18 64.4 3.0 4.5e-17 62.2 0.1 3.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PKS_DE PF18369.1 KIR65896.1 - 1.3e-14 54.4 7.9 1.3e-14 54.4 7.9 7.9 6 2 1 7 7 6 1 Polyketide synthase dimerisation element domain adh_short_C2 PF13561.6 KIR65896.1 - 7.8e-14 51.8 5.3 1.1e-09 38.2 1.9 2.9 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Docking PF08990.11 KIR65896.1 - 4.4e-11 42.2 7.4 1.5e-10 40.5 7.4 2.1 1 0 0 1 1 1 1 Erythronolide synthase docking Thiolase_N PF00108.23 KIR65896.1 - 9.6e-11 41.5 13.7 3.2e-07 30.0 0.2 3.8 4 0 0 4 4 4 2 Thiolase, N-terminal domain Epimerase PF01370.21 KIR65896.1 - 5.3e-09 35.9 11.4 2.1e-05 24.1 0.3 3.0 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIR65896.1 - 1.2e-08 34.4 0.0 0.0045 16.2 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIR65896.1 - 1.6e-07 31.0 0.0 0.00072 19.0 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 KIR65896.1 - 7.5e-06 25.8 2.6 2.7e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 KIR65896.1 - 0.0033 17.0 1.5 1.1 8.8 0.1 2.6 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 KIR65896.1 - 0.0099 14.9 0.0 0.097 11.7 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family SAT PF16073.5 KIR65896.1 - 0.025 14.3 8.9 0.23 11.1 0.0 3.8 2 2 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KIR65896.1 - 0.22 11.4 3.3 1.8 8.5 0.4 3.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3864 PF12980.7 KIR65896.1 - 0.29 11.5 0.6 4.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) YAcAr PF10686.9 KIR65896.1 - 4.8 7.2 13.8 8 6.5 0.1 5.7 5 0 0 5 5 4 0 YspA, cpYpsA-related SLOG family ketoacyl-synt PF00109.26 KIR65897.1 - 1.9e-271 895.8 29.4 1.6e-92 309.6 2.3 6.6 7 0 0 7 7 6 3 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65897.1 - 1.7e-225 747.4 14.7 1.1e-91 307.7 1.7 3.6 3 0 0 3 3 3 3 Acyl transferase domain KR PF08659.10 KIR65897.1 - 9.3e-175 576.3 32.6 1.8e-61 207.2 2.3 4.9 6 0 0 6 6 5 3 KR domain Ketoacyl-synt_C PF02801.22 KIR65897.1 - 4.6e-137 449.2 14.2 7.8e-46 154.9 0.4 4.2 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR65897.1 - 1.3e-47 160.9 0.0 5.5e-16 59.0 0.0 3.6 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65897.1 - 4.6e-44 148.6 0.0 2.6e-14 53.3 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site adh_short PF00106.25 KIR65897.1 - 1.1e-35 122.9 13.9 1.5e-11 44.1 0.2 5.1 5 0 0 5 5 5 3 short chain dehydrogenase PKS_DE PF18369.1 KIR65897.1 - 2e-33 114.7 34.1 1.2e-13 51.4 5.5 8.6 10 0 0 10 10 5 3 Polyketide synthase dimerisation element domain Epimerase PF01370.21 KIR65897.1 - 6.2e-23 81.5 10.7 1.2e-07 31.5 0.6 3.6 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KIR65897.1 - 2.2e-22 79.7 13.0 1.3e-07 31.3 0.1 4.4 4 0 0 4 4 3 3 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KIR65897.1 - 1.3e-18 67.6 0.0 2.7e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIR65897.1 - 1.7e-14 53.7 0.0 0.00027 20.2 0.0 3.2 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein Docking PF08990.11 KIR65897.1 - 1.7e-08 33.9 9.3 6.1e-08 32.1 9.3 2.1 1 0 0 1 1 1 1 Erythronolide synthase docking NmrA PF05368.13 KIR65897.1 - 4.5e-07 29.7 10.1 0.035 13.6 0.4 3.4 3 0 0 3 3 3 3 NmrA-like family 3Beta_HSD PF01073.19 KIR65897.1 - 9.2e-07 28.1 0.0 0.0021 17.1 0.0 3.2 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family SAT PF16073.5 KIR65897.1 - 2.7e-06 27.3 13.1 0.35 10.6 0.0 5.3 3 2 0 3 3 3 3 Starter unit:ACP transacylase in aflatoxin biosynthesis RmlD_sub_bind PF04321.17 KIR65897.1 - 0.00065 18.9 11.0 0.21 10.6 0.3 3.4 3 0 0 3 3 3 3 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIR65897.1 - 0.0013 18.7 5.9 0.0013 18.7 5.9 6.0 6 0 0 6 6 5 2 NAD(P)H-binding NAD_binding_4 PF07993.12 KIR65897.1 - 0.0054 15.9 3.5 1.6 7.8 0.1 3.3 3 0 0 3 3 3 2 Male sterility protein ACP_syn_III PF08545.10 KIR65897.1 - 0.031 14.1 16.1 0.68 9.8 0.7 5.0 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III F420_oxidored PF03807.17 KIR65897.1 - 0.06 13.9 7.4 5.8 7.6 0.2 4.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent GBP_PSP PF02425.15 KIR65897.1 - 0.14 11.8 5.8 4.8 6.9 0.1 3.7 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Semialdhyde_dh PF01118.24 KIR65897.1 - 0.87 10.0 4.6 8.3 6.9 0.2 3.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 KIR65898.1 - 2.3e-176 584.4 15.9 1.2e-90 303.5 0.2 3.5 4 0 0 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65898.1 - 2.4e-136 454.4 7.5 3.7e-79 266.5 0.3 2.5 2 0 0 2 2 2 2 Acyl transferase domain KR PF08659.10 KIR65898.1 - 5e-114 378.4 19.3 6.9e-58 195.5 2.8 3.8 4 0 0 4 4 4 2 KR domain PS-DH PF14765.6 KIR65898.1 - 2.8e-105 351.8 5.7 4.4e-52 177.2 0.3 2.7 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KIR65898.1 - 3.2e-88 291.7 13.7 2.3e-44 150.2 0.6 3.2 3 0 0 3 3 2 2 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR65898.1 - 1.5e-32 112.4 0.0 1.4e-15 57.7 0.0 2.5 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 KIR65898.1 - 2.5e-27 95.0 0.0 1e-13 51.4 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 KIR65898.1 - 2.2e-23 82.8 5.4 2.6e-12 46.6 0.1 3.9 4 0 0 4 4 4 2 short chain dehydrogenase Docking PF08990.11 KIR65898.1 - 6.1e-13 48.1 6.2 1.5e-12 46.9 6.2 1.8 1 0 0 1 1 1 1 Erythronolide synthase docking Thiolase_N PF00108.23 KIR65898.1 - 3e-10 39.9 8.5 1.8e-05 24.2 0.2 3.2 3 0 0 3 3 3 2 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 KIR65898.1 - 1.5e-07 30.9 0.0 0.00062 19.0 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIR65898.1 - 6.3e-07 29.1 7.4 0.00078 19.0 0.3 2.8 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65898.1 - 0.00018 21.0 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIR65898.1 - 0.0041 16.3 2.2 0.96 8.6 0.2 2.4 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KIR65898.1 - 0.0041 16.7 6.0 0.62 9.6 0.5 2.5 2 0 0 2 2 2 2 NmrA-like family ACP_syn_III PF08545.10 KIR65898.1 - 0.03 14.2 3.0 7.4 6.5 0.4 3.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAT PF16073.5 KIR65898.1 - 0.079 12.7 6.6 0.72 9.5 1.2 3.5 3 1 0 3 3 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Semialdhyde_dh PF01118.24 KIR65898.1 - 0.15 12.5 1.4 8.5 6.8 0.1 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KIR65898.1 - 0.15 11.1 3.6 4.2 6.4 0.5 2.6 2 1 0 2 2 2 0 RmlD substrate binding domain ketoacyl-synt PF00109.26 KIR65899.1 - 5.7e-92 307.9 0.1 1.8e-91 306.2 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65899.1 - 5.6e-80 269.2 1.1 1e-79 268.4 1.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KIR65899.1 - 2.9e-54 183.7 5.2 5.1e-54 182.9 1.8 2.9 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.22 KIR65899.1 - 3.4e-44 149.6 0.3 9.6e-44 148.2 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR65899.1 - 4.1e-14 53.0 0.0 9.1e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PKS_DE PF18369.1 KIR65899.1 - 4.3e-13 49.6 4.4 4.3e-13 49.6 4.4 5.5 6 0 0 6 6 5 1 Polyketide synthase dimerisation element domain adh_short PF00106.25 KIR65899.1 - 4.7e-13 49.0 1.0 1.7e-11 44.0 0.1 2.7 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 KIR65899.1 - 1.2e-12 48.0 0.0 3.3e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Docking PF08990.11 KIR65899.1 - 7.9e-09 35.0 1.7 2.2e-08 33.6 1.7 1.8 1 0 0 1 1 1 1 Erythronolide synthase docking Epimerase PF01370.21 KIR65899.1 - 1.2e-06 28.2 0.1 2.2e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 KIR65899.1 - 1.4e-06 27.9 2.8 1.8e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 KIR65899.1 - 0.00057 19.4 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIR65899.1 - 0.0051 16.0 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SAT PF16073.5 KIR65899.1 - 0.0072 16.1 1.8 0.13 12.0 0.0 2.8 1 1 1 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis NmrA PF05368.13 KIR65899.1 - 0.11 12.1 0.2 0.27 10.7 0.2 1.7 1 0 0 1 1 1 0 NmrA-like family ketoacyl-synt PF00109.26 KIR65900.1 - 4.1e-90 301.8 5.9 8.3e-90 300.8 2.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIR65900.1 - 1e-53 182.9 0.4 1e-53 182.9 0.4 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KIR65900.1 - 2.6e-46 156.5 0.9 2.6e-46 156.5 0.9 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KIR65900.1 - 8e-21 75.2 0.4 3.5e-17 63.3 0.0 3.6 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KIR65900.1 - 1e-15 57.8 0.2 2.2e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KIR65900.1 - 1e-15 58.1 0.0 2.5e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PikAIV_N PF18605.1 KIR65900.1 - 1.8e-10 40.2 3.3 5.4e-10 38.7 3.3 1.9 1 0 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Thiolase_N PF00108.23 KIR65900.1 - 2.7e-07 30.2 0.3 1.3e-06 28.0 0.2 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KIR65900.1 - 1.8e-06 28.8 14.8 1.8e-06 28.8 14.8 6.3 2 1 3 5 5 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR65900.1 - 0.0054 16.0 0.9 1.7 7.9 0.2 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIR65900.1 - 0.0064 16.3 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR65900.1 - 0.021 14.5 0.3 0.78 9.3 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold ABC_tran PF00005.27 KIR65901.1 - 2.5e-28 99.3 0.0 4.8e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65901.1 - 1e-07 32.1 0.4 0.00044 20.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KIR65901.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KIR65901.1 - 0.0019 18.0 1.8 0.005 16.6 0.7 2.1 1 1 0 2 2 2 1 AAA domain DUF4162 PF13732.6 KIR65901.1 - 0.0052 17.5 0.0 0.033 14.9 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 KIR65901.1 - 0.0061 16.0 0.2 0.051 13.0 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR65901.1 - 0.019 15.4 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIR65901.1 - 0.065 12.1 0.1 0.29 10.0 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 KIR65901.1 - 0.14 12.6 1.9 7.4 7.0 1.9 3.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIR65901.1 - 0.16 12.5 0.8 0.26 11.8 0.8 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KIR65902.1 - 5.6e-19 68.4 19.4 8.9e-19 67.7 19.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR65902.1 - 5.7e-07 29.0 17.4 5.7e-07 29.0 17.4 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein Gly-zipper_OmpA PF13436.6 KIR65902.1 - 0.012 15.4 1.8 0.012 15.4 1.8 2.2 2 0 0 2 2 2 0 Glycine-zipper domain DUF2427 PF10348.9 KIR65902.1 - 1.2 9.0 5.1 0.42 10.4 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Bacteriocin_IIc PF10439.9 KIR65902.1 - 1.4 9.1 7.8 6.6 6.9 0.7 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide AMP-binding PF00501.28 KIR65903.1 - 4.8e-52 177.0 0.1 6.8e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR65903.1 - 1.3e-16 61.3 0.3 1.3e-16 61.3 0.3 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 4PPT_N PF17837.1 KIR65904.1 - 1.3e-27 95.7 0.4 3.3e-27 94.4 0.4 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 KIR65904.1 - 2.6e-11 43.7 0.0 6.7e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily AMP-binding PF00501.28 KIR65905.1 - 8.9e-71 238.7 0.1 3e-70 237.0 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR65905.1 - 8.6e-19 68.3 0.3 8.6e-19 68.3 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KIR65906.1 - 7.4e-29 101.0 0.0 1.1e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65906.1 - 2.8e-10 40.5 0.0 4.7e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KIR65906.1 - 4.2e-05 24.2 0.0 0.00018 22.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 KIR65906.1 - 4.3e-05 23.0 0.0 0.024 14.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIR65906.1 - 0.00016 21.4 0.8 0.0015 18.3 0.8 2.1 1 1 0 1 1 1 1 AAA domain KdpD PF02702.17 KIR65906.1 - 0.00093 18.7 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain ATP_bind_1 PF03029.17 KIR65906.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KIR65906.1 - 0.0043 17.6 0.1 0.0072 16.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KIR65906.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIR65906.1 - 0.033 14.6 1.4 0.071 13.5 1.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 KIR65906.1 - 0.039 13.5 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KIR65906.1 - 0.04 14.2 0.1 2.6 8.3 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KIR65906.1 - 0.042 14.1 0.2 0.17 12.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIR65906.1 - 0.061 13.0 0.1 19 4.9 0.0 3.1 3 1 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 KIR65906.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lantibiotic_a PF14867.6 KIR65906.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Lantibiotic alpha ABC2_membrane PF01061.24 KIR65907.1 - 3.2e-25 88.8 8.9 4.8e-25 88.2 8.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR65907.1 - 5.7e-16 58.6 6.5 5.7e-16 58.6 6.5 1.7 1 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KIR65907.1 - 0.00014 21.3 15.8 0.00036 19.9 15.8 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR65907.1 - 0.01 15.8 4.7 0.018 15.0 4.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF373 PF04123.13 KIR65907.1 - 0.054 12.9 3.0 0.082 12.3 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2070 PF09843.9 KIR65907.1 - 0.48 8.6 8.8 0.69 8.1 8.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_30 PF13604.6 KIR65908.1 - 1.9e-44 151.7 0.3 1.9e-44 151.7 0.3 1.9 2 0 0 2 2 2 1 AAA domain HHH_4 PF14490.6 KIR65908.1 - 1.2e-37 127.8 0.0 2.6e-32 110.6 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix containing domain AAA_19 PF13245.6 KIR65908.1 - 1.5e-33 116.2 0.1 4e-33 114.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KIR65908.1 - 7.4e-20 70.5 0.0 1.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 KIR65908.1 - 1.6e-19 69.4 1.0 4.8e-19 67.9 1.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KIR65908.1 - 6.2e-10 39.2 0.0 0.00081 19.2 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase HHH_5 PF14520.6 KIR65908.1 - 1.3e-06 29.0 5.4 7.7e-06 26.4 0.2 3.5 4 0 0 4 4 3 1 Helix-hairpin-helix domain AAA_11 PF13086.6 KIR65908.1 - 3.6e-06 27.0 1.4 0.0022 17.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 KIR65908.1 - 1.7e-05 24.7 3.5 0.00051 19.9 3.5 2.4 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 KIR65908.1 - 0.0025 17.0 0.8 0.013 14.7 0.0 2.2 2 1 0 2 2 2 1 PIF1-like helicase UvrD_C PF13361.6 KIR65908.1 - 0.0076 15.7 0.1 0.014 14.8 0.1 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KIR65908.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KIR65908.1 - 0.021 14.2 0.6 0.056 12.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 KIR65908.1 - 0.045 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain IMS_HHH PF11798.8 KIR65908.1 - 0.052 13.9 0.3 25 5.5 0.0 3.3 3 0 0 3 3 3 0 IMS family HHH motif HHH PF00633.23 KIR65908.1 - 0.069 13.1 0.9 0.6 10.1 0.3 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 KIR65908.1 - 0.11 12.3 0.1 22 5.0 0.0 2.9 2 1 0 2 2 2 0 Fingers domain of DNA polymerase lambda AAA_16 PF13191.6 KIR65908.1 - 0.11 12.8 0.2 0.37 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIR65908.1 - 0.17 11.8 0.2 0.56 10.1 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.7 KIR65908.1 - 0.18 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 KIR65908.1 - 0.18 12.3 0.0 0.67 10.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF664 PF04978.12 KIR65909.1 - 1.4e-18 67.7 0.9 4.5e-18 66.1 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR65909.1 - 2.5e-16 60.4 2.3 3.1e-16 60.0 2.3 1.1 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 KIR65909.1 - 0.025 14.5 0.0 0.071 13.0 0.0 1.6 1 1 0 1 1 1 0 DinB family ADH_N PF08240.12 KIR65910.1 - 9.9e-27 93.0 0.3 2.6e-26 91.6 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR65910.1 - 3.6e-21 75.5 0.4 8.1e-21 74.4 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR65910.1 - 5.4e-10 40.4 0.1 1.4e-09 39.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Met_10 PF02475.16 KIR65910.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 KIR65910.1 - 0.15 11.6 0.1 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase small domain 2-Hacid_dh_C PF02826.19 KIR65910.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIR65910.1 - 0.65 9.3 4.0 0.16 11.3 0.7 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SCP2 PF02036.17 KIR65911.1 - 3.6e-09 37.0 0.0 4.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIR65911.1 - 0.0026 18.0 0.0 0.003 17.8 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal GDE_N_bis PF14742.6 KIR65912.1 - 6.3e-38 130.3 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of (some) glycogen debranching enzymes GDE_C PF06202.14 KIR65912.1 - 8.5e-06 24.9 0.0 5e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase DUF664 PF04978.12 KIR65913.1 - 2.2e-45 154.8 3.7 2.5e-45 154.6 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 KIR65913.1 - 1.7e-11 44.7 13.9 6e-11 43.0 7.2 1.9 1 1 1 2 2 2 2 DinB superfamily MDMPI_N PF11716.8 KIR65913.1 - 0.00045 20.9 15.1 0.0041 17.8 9.5 2.3 1 1 1 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.12 KIR65913.1 - 0.0018 18.2 0.1 0.02 14.8 0.1 2.1 1 1 0 1 1 1 1 DinB family GSK-3_bind PF05350.12 KIR65913.1 - 0.0033 16.8 0.1 0.0046 16.3 0.1 1.2 1 0 0 1 1 1 1 Glycogen synthase kinase-3 binding TetR_C_34 PF17929.1 KIR65913.1 - 0.046 13.8 0.3 1.4 9.0 0.0 2.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF72 PF01904.18 KIR65914.1 - 7.6e-57 192.9 0.0 8.7e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 CopD PF05425.13 KIR65915.1 - 0.018 15.4 3.4 0.037 14.4 3.4 1.6 1 0 0 1 1 1 0 Copper resistance protein D Transgly_assoc PF04226.13 KIR65915.1 - 1.8 8.9 6.3 22 5.4 0.0 3.3 3 0 0 3 3 3 0 Transglycosylase associated protein Hydrolase_4 PF12146.8 KIR65916.1 - 2.3e-16 59.8 0.9 1.2e-15 57.5 0.9 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR65916.1 - 1.8e-14 54.0 0.1 2.1e-11 43.9 0.3 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR65916.1 - 1.4e-08 35.7 25.7 1.4e-08 35.7 25.7 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KIR65916.1 - 0.00026 21.2 0.2 0.00041 20.5 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KIR65916.1 - 0.0051 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 KIR65916.1 - 0.0073 16.2 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Esterase PF00756.20 KIR65916.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative esterase LIDHydrolase PF10230.9 KIR65916.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Glycos_transf_1 PF00534.20 KIR65917.1 - 8.5e-32 110.0 0.0 1.5e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR65917.1 - 1.3e-29 103.3 0.7 3e-29 102.1 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR65917.1 - 5.3e-29 101.7 21.3 5.3e-29 101.7 21.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR65917.1 - 1.6e-28 99.8 6.7 1.6e-28 99.8 6.7 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIR65917.1 - 1.2e-10 41.6 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIR65917.1 - 8.4e-05 22.4 0.1 0.059 13.1 0.0 2.4 2 0 0 2 2 2 2 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 KIR65917.1 - 0.00026 21.0 0.0 0.00074 19.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glycogen_syn PF05693.13 KIR65917.1 - 0.12 10.9 0.3 0.2 10.2 0.0 1.6 2 0 0 2 2 2 0 Glycogen synthase Globin PF00042.22 KIR65918.1 - 1.7e-10 41.5 0.0 2.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 KIR65918.1 - 3.4e-10 40.5 0.0 6.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIR65918.1 - 1.2e-08 35.2 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 KIR65918.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 KIR65918.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Rrf2 PF02082.20 KIR65919.1 - 5.4e-17 61.9 0.6 9.3e-17 61.2 0.6 1.4 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 KIR65919.1 - 1.5e-05 24.8 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 KIR65919.1 - 3.3e-05 23.6 2.0 0.00016 21.4 0.5 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR65919.1 - 0.00014 21.7 1.0 0.00014 21.7 1.0 2.4 2 1 1 3 3 3 1 MarR family HTH_24 PF13412.6 KIR65919.1 - 0.00052 19.5 0.1 0.00087 18.8 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KIR65919.1 - 0.00072 19.5 0.9 0.001 19.0 0.2 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 KIR65919.1 - 0.0017 18.2 0.1 0.0029 17.5 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_28 PF13518.6 KIR65919.1 - 0.0031 17.6 0.1 0.0031 17.6 0.1 2.2 2 2 0 3 3 3 1 Helix-turn-helix domain HTH_27 PF13463.6 KIR65919.1 - 0.0052 17.3 0.1 0.013 15.9 0.1 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain DUF4423 PF14394.6 KIR65919.1 - 0.0057 16.4 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) DprA_WH PF17782.1 KIR65919.1 - 0.0098 16.0 4.1 0.01 15.9 0.4 2.4 2 0 0 2 2 2 1 DprA winged helix domain HTH_20 PF12840.7 KIR65919.1 - 0.0099 15.9 1.6 0.0099 15.9 1.6 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain EPSP_synthase PF00275.20 KIR65919.1 - 0.017 13.9 0.2 0.02 13.6 0.2 1.1 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HTH_AsnC-type PF13404.6 KIR65919.1 - 0.024 14.4 0.7 0.06 13.2 0.7 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 KIR65919.1 - 0.035 14.1 0.5 0.073 13.1 0.2 1.8 2 0 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 KIR65919.1 - 0.035 13.8 2.6 0.047 13.4 1.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family MarR PF01047.22 KIR65919.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 KIR65919.1 - 0.075 12.9 0.9 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Fe_dep_repress PF01325.19 KIR65919.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MukE PF04288.13 KIR65919.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 MukE-like family IF2_N PF04760.15 KIR65919.1 - 0.21 11.4 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Methyltransf_11 PF08241.12 KIR65920.1 - 9.2e-19 67.9 0.0 1.8e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR65920.1 - 7.6e-15 55.4 0.5 4.6e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR65920.1 - 4.5e-12 46.1 0.0 5.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65920.1 - 5.5e-09 36.7 0.0 5.7e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR65920.1 - 2.2e-08 33.7 0.0 2.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIR65920.1 - 7.1e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIR65920.1 - 9.4e-05 22.4 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_17 PF12692.7 KIR65920.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine methyltransferase DUF412 PF04217.13 KIR65920.1 - 0.067 13.1 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF412 Lipase_GDSL_2 PF13472.6 KIR65921.1 - 5e-07 30.3 2.2 7.7e-06 26.4 2.2 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR65921.1 - 0.00013 22.0 0.0 0.058 13.4 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase DNA_topoisoIV PF00521.20 KIR65922.1 - 1.5e-141 472.2 0.0 1.7e-141 472.0 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 KIR65922.1 - 1e-14 53.7 0.5 9.3e-05 21.8 0.0 5.6 5 0 0 5 5 5 3 DNA gyrase C-terminal domain, beta-propeller Lzipper-MIP1 PF14389.6 KIR65922.1 - 0.051 13.9 0.6 0.096 13.0 0.6 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Xan_ur_permease PF00860.20 KIR65923.1 - 1e-84 284.5 36.1 1.2e-84 284.3 36.1 1.0 1 0 0 1 1 1 1 Permease family 2OG-FeII_Oxy_2 PF13532.6 KIR65924.1 - 9.8e-14 52.0 0.0 1.2e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1616 PF07760.11 KIR65925.1 - 0.033 13.6 1.1 0.099 12.0 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) CTP_transf_3 PF02348.19 KIR65926.1 - 1.7e-24 87.0 0.0 2.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 KIR65926.1 - 1.2e-07 32.3 9.1 5.5e-07 30.1 9.1 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain LolB PF03550.14 KIR65926.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.5 1 1 1 2 2 2 0 Outer membrane lipoprotein LolB Methyltransf_23 PF13489.6 KIR65927.1 - 0.0093 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65927.1 - 0.022 15.4 0.0 0.064 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DegT_DnrJ_EryC1 PF01041.17 KIR65929.1 - 3.4e-113 378.6 0.0 3.9e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIR65929.1 - 8e-05 22.0 0.0 0.00019 20.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR65929.1 - 0.00078 18.1 0.1 0.0011 17.6 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PALP PF00291.25 KIR65929.1 - 0.0021 17.5 2.8 0.0029 17.1 2.8 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Polysacc_synt_2 PF02719.15 KIR65930.1 - 6e-98 327.6 0.0 6.9e-98 327.4 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIR65930.1 - 5e-25 88.4 0.2 3e-24 85.8 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR65930.1 - 5.3e-16 58.5 0.0 1.6e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KIR65930.1 - 6.1e-16 58.7 0.0 1.1e-14 54.6 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR65930.1 - 9.4e-15 54.3 0.0 1.9e-14 53.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIR65930.1 - 1.2e-12 48.1 0.2 1.6e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR65930.1 - 1.7e-07 31.1 0.1 2.9e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIR65930.1 - 2e-07 30.4 1.0 0.00017 20.8 0.9 3.0 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 KIR65930.1 - 3.5e-06 26.6 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR65930.1 - 3.3e-05 23.9 0.0 6.2e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NeuB PF03102.14 KIR65931.1 - 9.7e-80 267.5 0.0 1.2e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 KIR65931.1 - 9.9e-08 32.5 0.1 1.9e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 SAF domain Isochorismatase PF00857.20 KIR65931.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 Isochorismatase family PS_pyruv_trans PF04230.13 KIR65932.1 - 1.2e-21 78.0 0.0 1.8e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase GARP PF16731.5 KIR65934.1 - 0.0052 16.5 8.3 0.0052 16.5 8.3 2.2 2 0 0 2 2 2 1 Glutamic acid/alanine-rich protein of Trypanosoma Sigma70_r1_2 PF00140.20 KIR65934.1 - 0.094 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 M64_N PF16217.5 KIR65934.1 - 0.22 11.1 0.1 0.36 10.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M64 N-terminus Peptidase_C39_2 PF13529.6 KIR65935.1 - 2.9e-18 66.8 0.0 4.5e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Phytochelatin PF05023.14 KIR65935.1 - 5.1e-05 22.6 0.1 0.00084 18.6 0.1 2.1 1 1 0 1 1 1 1 Phytochelatin synthase BtrH_N PF14399.6 KIR65935.1 - 0.088 13.1 0.2 0.38 11.0 0.1 2.1 2 1 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal PRCC PF10253.9 KIR65935.1 - 0.1 13.4 2.6 0.13 13.1 2.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting HoxA13_N PF12284.8 KIR65935.1 - 0.35 11.5 10.9 0.046 14.3 6.8 1.6 2 0 0 2 2 2 0 Hox protein A13 N terminal Glyphos_transf PF04464.14 KIR65936.1 - 7.1e-07 28.5 0.0 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase EI24 PF07264.11 KIR65936.1 - 0.96 9.7 9.0 6.1 7.1 9.0 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) IspD PF01128.19 KIR65937.1 - 4.3e-49 167.2 0.9 7.6e-49 166.4 0.9 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.25 KIR65937.1 - 3.6e-33 114.7 0.1 1.1e-30 106.6 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR65937.1 - 1e-28 100.5 0.1 4.2e-28 98.5 0.1 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NTP_transf_3 PF12804.7 KIR65937.1 - 8.9e-12 45.7 0.5 2.5e-11 44.2 0.2 2.0 1 1 1 2 2 2 1 MobA-like NTP transferase domain KR PF08659.10 KIR65937.1 - 9.2e-08 32.2 0.3 1.8e-06 28.0 0.1 2.3 1 1 1 2 2 2 1 KR domain NTP_transferase PF00483.23 KIR65937.1 - 3e-05 23.7 0.0 6.9e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase RmlD_sub_bind PF04321.17 KIR65937.1 - 0.00048 19.3 0.1 0.00076 18.7 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIR65937.1 - 0.041 13.3 0.2 0.14 11.6 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CTP_transf_3 PF02348.19 KIR65937.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase 2-Hacid_dh_C PF02826.19 KIR65937.1 - 0.098 12.0 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPGP PF01704.18 KIR65937.1 - 0.25 9.9 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase ABC2_membrane PF01061.24 KIR65938.1 - 3.3e-15 56.1 16.4 3.3e-15 56.1 16.4 1.4 2 0 0 2 2 2 1 ABC-2 type transporter DUF202 PF02656.15 KIR65938.1 - 4.1 7.9 7.5 3.6 8.1 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TetR_C_11 PF16859.5 KIR65939.1 - 8.7e-30 103.3 8.6 8.7e-30 103.3 8.6 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65939.1 - 5.6e-13 48.5 0.1 1.3e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 KIR65939.1 - 0.00042 20.1 0.7 0.0013 18.5 0.7 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 KIR65939.1 - 0.0025 17.6 0.9 0.0062 16.3 0.9 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TetR_C_7 PF14246.6 KIR65939.1 - 0.0027 17.7 0.8 0.0027 17.7 0.8 1.6 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain HTH_20 PF12840.7 KIR65939.1 - 0.024 14.7 2.1 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KIR65939.1 - 0.084 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 KIR65939.1 - 0.091 12.9 0.9 0.3 11.2 0.9 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 KIR65939.1 - 5.5 7.4 12.8 0.08 13.3 1.1 3.0 3 1 0 3 3 3 0 Helix-turn-helix domain DAO PF01266.24 KIR65940.1 - 1.7e-64 218.7 9.9 2e-64 218.4 9.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR65940.1 - 1.9e-05 24.0 3.3 0.094 11.9 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR65940.1 - 0.00023 21.3 1.6 0.0005 20.2 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIR65940.1 - 0.00053 19.4 0.6 0.0063 15.8 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIR65940.1 - 0.0015 17.7 1.8 0.0053 15.8 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Mqo PF06039.15 KIR65940.1 - 0.0015 17.2 0.2 6 5.3 0.0 3.0 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 KIR65940.1 - 0.0026 18.3 0.4 0.12 13.0 0.4 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIR65940.1 - 0.0095 15.9 2.8 0.59 10.1 0.3 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIR65940.1 - 0.011 15.1 0.2 3.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR65940.1 - 0.02 14.0 4.5 0.95 8.5 4.5 2.2 1 1 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KIR65940.1 - 0.028 14.7 0.6 0.1 12.9 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain GMC_oxred_N PF00732.19 KIR65940.1 - 0.031 13.6 0.2 0.072 12.4 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase PTH2 PF01981.16 KIR65940.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 DegT_DnrJ_EryC1 PF01041.17 KIR65941.1 - 8.1e-106 354.4 0.0 9.2e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIR65941.1 - 2e-08 33.9 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KIR65941.1 - 5e-08 32.5 0.0 8.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR65941.1 - 0.00012 20.7 0.0 0.00019 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1967 PF09269.11 KIR65941.1 - 0.0077 16.1 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) SHMT PF00464.19 KIR65941.1 - 0.091 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Epimerase PF01370.21 KIR65942.1 - 1.2e-53 182.0 0.0 1.5e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65942.1 - 1.4e-51 175.9 0.0 1.8e-50 172.2 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR65942.1 - 8.6e-26 90.6 0.0 1.1e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIR65942.1 - 2.2e-20 73.3 0.0 7.3e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIR65942.1 - 4e-13 49.1 0.0 7.5e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIR65942.1 - 6.3e-13 48.5 0.0 3.1e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIR65942.1 - 3.8e-10 39.4 0.0 1.4e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KIR65942.1 - 5.9e-08 32.5 0.4 8.7e-07 28.7 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KIR65942.1 - 0.0001 21.8 0.2 0.0002 20.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR65942.1 - 0.011 15.7 0.4 0.035 14.0 0.4 1.9 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 KIR65942.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 KIR65942.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Glycos_transf_1 PF00534.20 KIR65943.1 - 8.6e-20 71.0 0.0 1.3e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR65943.1 - 1e-19 71.5 5.4 1e-19 71.5 5.4 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KIR65943.1 - 2.6e-18 66.7 0.2 4.5e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR65943.1 - 1.1e-17 64.5 0.7 1.1e-17 64.5 0.7 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 KIR65943.1 - 2e-08 34.4 0.0 5.7e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KIR65943.1 - 4.3e-06 27.0 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIR65943.1 - 0.095 12.4 0.3 1 9.0 0.1 2.3 1 1 1 2 2 2 0 Starch synthase catalytic domain RPN1_C PF18051.1 KIR65943.1 - 0.099 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Hexapep_2 PF14602.6 KIR65944.1 - 2.4e-10 40.0 9.6 8.6e-09 35.0 2.1 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KIR65944.1 - 2.2e-09 36.7 7.4 5.9e-06 25.8 2.3 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KIR65945.1 - 4.4e-05 23.7 0.4 7e-05 23.1 0.4 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site LytR_cpsA_psr PF03816.14 KIR65945.1 - 0.0033 17.6 0.0 0.0044 17.2 0.0 1.3 1 1 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain PP-binding_2 PF14573.6 KIR65945.1 - 0.025 14.8 0.1 0.028 14.6 0.1 1.1 1 0 0 1 1 1 0 Acyl-carrier adh_short_C2 PF13561.6 KIR65946.1 - 3e-60 203.7 14.3 3.9e-60 203.3 14.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR65946.1 - 6.2e-51 172.6 7.5 8.1e-51 172.3 7.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR65946.1 - 5e-13 49.4 11.9 2.5e-12 47.1 11.9 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR65946.1 - 3.2e-05 23.5 3.6 9e-05 22.0 3.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIR65946.1 - 0.0021 18.1 0.2 0.0046 17.0 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIR65946.1 - 0.0086 16.6 0.7 0.018 15.6 0.5 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 KIR65946.1 - 0.014 15.4 4.7 0.014 15.4 4.7 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KIR65946.1 - 0.041 14.1 0.3 0.085 13.1 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HEAT_PBS PF03130.16 KIR65946.1 - 0.073 13.8 0.3 0.073 13.8 0.3 3.7 3 1 1 4 4 3 0 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 KIR65946.1 - 0.61 10.5 7.0 0.25 11.8 2.9 2.5 2 1 0 2 2 2 0 HEAT repeats Robl_LC7 PF03259.17 KIR65946.1 - 4.9 7.0 12.1 6.5 6.6 0.9 3.3 2 2 1 3 3 3 0 Roadblock/LC7 domain AMP-binding PF00501.28 KIR65947.1 - 1.7e-47 162.0 0.0 2.4e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme GGDEF_2 PF17853.1 KIR65947.1 - 0.019 15.2 0.9 0.31 11.3 0.0 2.6 2 0 0 2 2 2 0 GGDEF-like domain CbiG_N PF11760.8 KIR65947.1 - 0.047 13.7 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal LuxE PF04443.12 KIR65948.1 - 4.4e-44 151.0 0.0 5.1e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Acyl-protein synthetase, LuxE AMP-binding PF00501.28 KIR65948.1 - 0.057 12.0 0.2 0.13 10.9 0.2 1.7 1 1 0 1 1 1 0 AMP-binding enzyme LuxC PF05893.14 KIR65949.1 - 3.2e-35 121.9 0.0 1.6e-34 119.7 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) LPG_synthase_TM PF03706.13 KIR65950.1 - 6.1e-23 81.8 47.6 7.9e-23 81.4 47.6 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DegT_DnrJ_EryC1 PF01041.17 KIR65951.1 - 7.6e-121 403.8 0.0 8.5e-121 403.6 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIR65951.1 - 3.9e-06 26.3 0.3 1.4e-05 24.5 0.3 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIR65951.1 - 7.6e-06 25.1 0.0 5.6e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR65951.1 - 3.2e-05 22.6 0.0 4.6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyphos_transf PF04464.14 KIR65952.1 - 1.6e-07 30.7 0.0 2.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Hexapep PF00132.24 KIR65953.1 - 1.5e-21 75.3 12.4 6.4e-07 28.9 1.5 3.9 2 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIR65953.1 - 7.3e-15 54.4 12.7 1.3e-06 28.0 2.4 4.0 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase GatD_N PF18195.1 KIR65953.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 GatD N-terminal domain DUF952 PF06108.12 KIR65954.1 - 4.8e-32 109.8 0.0 5.5e-32 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF569 PF04601.13 KIR65954.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF569) Response_reg PF00072.24 KIR65955.1 - 1.6e-23 83.0 0.0 2.2e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR65955.1 - 3e-21 75.3 0.2 5.8e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 KIR65956.1 - 9.5e-16 58.3 0.0 1.9e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR65956.1 - 6e-10 39.4 0.1 2.3e-09 37.5 0.1 2.1 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 KIR65956.1 - 1.6e-09 37.7 3.5 1.6e-09 37.7 3.5 2.3 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KIR65956.1 - 0.00055 19.9 0.3 0.0014 18.6 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KIR65956.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 KIR65956.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Cache domain SLATT_1 PF18181.1 KIR65956.1 - 0.29 11.1 6.6 5.6 6.9 0.5 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 H2O2_YaaD PF03883.14 KIR65957.1 - 9.3e-36 123.5 0.0 1.1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA Laminin_G_3 PF13385.6 KIR65958.1 - 3.8e-28 98.6 6.2 3.8e-28 98.6 6.2 3.9 3 1 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily VCBS PF13517.6 KIR65958.1 - 2.2e-08 34.5 57.3 0.0044 17.6 0.7 7.8 6 2 2 8 8 8 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KIR65958.1 - 1.7e-07 31.2 26.7 0.013 15.6 0.0 6.6 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 KIR65958.1 - 0.012 14.9 8.2 1.2 8.5 0.1 4.4 5 1 1 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region W_rich_C PF07483.11 KIR65958.1 - 0.46 10.7 4.0 0.62 10.3 0.1 2.8 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain NifZ PF04319.13 KIR65960.1 - 0.039 13.8 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 NifZ domain Sensor PF13796.6 KIR65963.1 - 0.27 11.3 10.1 0.025 14.6 3.6 2.2 2 0 0 2 2 2 0 Putative sensor Asn_synthase PF00733.21 KIR65964.1 - 3.4e-45 155.2 0.1 1.1e-44 153.6 0.0 1.8 2 1 0 2 2 2 1 Asparagine synthase GATase_6 PF13522.6 KIR65964.1 - 1.7e-34 118.9 0.0 2.9e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIR65964.1 - 7.8e-34 116.2 0.0 1.3e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KIR65964.1 - 1.6e-07 31.0 0.0 3.7e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Aluminium induced protein CBM_48 PF02922.18 KIR65965.1 - 1.1e-23 83.3 0.1 4.2e-19 68.7 0.0 3.1 3 0 0 3 3 3 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 KIR65965.1 - 3.8e-20 72.2 0.0 1.1e-19 70.6 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KIR65965.1 - 2.3e-14 53.7 0.0 2.6e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 KIR65965.1 - 0.0028 17.8 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase DUF3459 PF11941.8 KIR65965.1 - 0.031 14.6 0.1 0.16 12.3 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_hydro_70 PF02324.16 KIR65965.1 - 0.052 11.7 0.0 0.082 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 DUF3416 PF11896.8 KIR65966.1 - 1.5e-50 172.0 1.4 2.4e-50 171.3 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Alpha-amylase PF00128.24 KIR65966.1 - 8.1e-05 22.3 0.0 0.003 17.2 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain GHL6 PF14871.6 KIR65966.1 - 0.00027 21.1 0.0 0.0008 19.6 0.0 1.7 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Sulfotransfer_3 PF13469.6 KIR65967.1 - 2.2e-12 47.9 0.0 1.7e-08 35.1 0.0 3.3 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_4 PF17784.1 KIR65967.1 - 0.024 14.5 0.0 0.062 13.1 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase domain TPR_19 PF14559.6 KIR65967.1 - 0.038 14.5 3.2 0.73 10.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Sulphotransf PF09037.10 KIR65967.1 - 0.075 12.6 0.1 3.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Stf0 sulphotransferase GntR PF00392.21 KIR65968.1 - 5.8e-20 70.7 0.0 6.5e-20 70.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 KIR65968.1 - 0.00033 20.3 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 KIR65968.1 - 0.027 15.0 0.0 0.028 14.9 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.20 KIR65968.1 - 0.037 14.4 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator LexA_DNA_bind PF01726.16 KIR65968.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 LexA DNA binding domain HTH_31 PF13560.6 KIR65970.1 - 3.9e-10 39.9 3.5 3.9e-10 39.9 3.5 4.2 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR65970.1 - 1.4e-06 28.3 0.2 4.2e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KIR65970.1 - 6.6e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR65970.1 - 0.026 14.5 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain KorB PF08535.10 KIR65970.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 KorB domain HTH_23 PF13384.6 KIR65970.1 - 0.17 11.7 3.8 0.22 11.4 0.2 3.0 2 1 1 3 3 3 0 Homeodomain-like domain Glyco_transf_4 PF13439.6 KIR65971.1 - 2.3e-32 112.4 4.2 3.3e-32 111.8 1.8 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIR65971.1 - 1.1e-28 100.0 0.0 1.5e-27 96.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR65971.1 - 7.7e-25 87.9 3.6 1.6e-24 86.8 0.6 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR65971.1 - 6.2e-22 78.7 9.5 6.2e-22 78.7 9.5 3.3 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIR65971.1 - 1.9e-09 37.8 0.8 2.4e-08 34.3 0.2 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIR65971.1 - 1.9e-05 24.5 0.7 0.002 17.9 0.3 2.4 1 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 KIR65971.1 - 0.0026 17.8 0.0 0.0051 16.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like DUF3492 PF11997.8 KIR65971.1 - 0.073 12.8 2.1 3.2 7.4 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) NTP_transferase PF00483.23 KIR65972.1 - 1e-67 228.3 0.0 1.3e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR65972.1 - 2e-08 34.7 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KIR65972.1 - 0.012 14.5 0.0 3.1 6.7 0.1 2.4 2 1 0 2 2 2 0 L-fucokinase Hexapep PF00132.24 KIR65972.1 - 0.054 13.2 0.1 0.054 13.2 0.1 3.3 3 1 1 4 4 4 0 Bacterial transferase hexapeptide (six repeats) PGM_PMM_I PF02878.16 KIR65973.1 - 4.9e-37 126.7 0.0 1.2e-36 125.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIR65973.1 - 4.5e-29 101.0 0.0 1e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIR65973.1 - 1e-11 45.4 0.1 2.6e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIR65973.1 - 3.7e-10 39.8 0.1 1.6e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Epimerase PF01370.21 KIR65974.1 - 1.2e-51 175.5 0.0 1.4e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR65974.1 - 3.3e-44 151.6 0.0 3.9e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR65974.1 - 5e-20 71.7 0.0 6.7e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIR65974.1 - 5e-12 45.6 0.0 4.2e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KIR65974.1 - 1.4e-10 40.8 0.0 1.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIR65974.1 - 5.8e-08 32.8 0.0 9.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIR65974.1 - 5.2e-05 22.5 0.6 0.052 12.7 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KIR65974.1 - 0.00085 18.9 0.1 0.0021 17.6 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Ldh_1_N PF00056.23 KIR65974.1 - 0.0067 16.5 0.4 0.018 15.1 0.3 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KIR65975.1 - 3e-92 308.9 0.0 3.4e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIR65975.1 - 4.7e-22 78.6 0.2 7.2e-21 74.7 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR65975.1 - 3.6e-17 62.3 0.0 4.8e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIR65975.1 - 6.1e-14 52.2 0.0 4.5e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_syn_2C PF08485.10 KIR65975.1 - 1.3e-13 50.4 0.0 2.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein C-terminal NAD_binding_10 PF13460.6 KIR65975.1 - 8.1e-13 48.7 0.5 1.3e-12 48.0 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIR65975.1 - 3e-08 33.1 0.0 1.8e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KIR65975.1 - 5.1e-07 29.8 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KIR65975.1 - 6.8e-07 29.1 0.0 8.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIR65975.1 - 1.1e-06 28.3 0.3 2.7e-06 27.0 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KIR65975.1 - 1.7e-06 27.4 2.8 0.00024 20.4 2.8 2.9 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KIR65975.1 - 3.6e-05 23.5 0.9 0.00012 21.7 0.9 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 KIR65975.1 - 0.0082 16.7 0.0 0.035 14.7 0.0 2.1 3 0 0 3 3 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIR65975.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KIR65975.1 - 0.061 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KIR65975.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KIR65976.1 - 9.3e-06 25.3 0.1 0.00043 19.8 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GPI PF06560.11 KIR65976.1 - 0.21 10.9 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) 2TM PF13239.6 KIR65977.1 - 1.3 9.4 3.5 3.4 8.0 0.0 3.0 3 0 0 3 3 3 0 2TM domain Glyco_trans_1_4 PF13692.6 KIR65978.1 - 6.6e-27 94.6 0.1 1e-26 94.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIR65978.1 - 4.5e-25 88.1 0.0 6.5e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIR65978.1 - 0.00045 20.5 0.0 0.0037 17.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 LpxI_N PF17930.1 KIR65978.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 LpxI N-terminal domain Polysacc_synt_2 PF02719.15 KIR65979.1 - 2e-91 306.2 0.0 2.3e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIR65979.1 - 2.6e-23 82.7 0.2 3.7e-22 79.0 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR65979.1 - 3.7e-16 59.0 0.1 5.4e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIR65979.1 - 3.8e-14 52.8 0.0 2.7e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIR65979.1 - 7.1e-13 48.8 0.7 1.1e-12 48.2 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIR65979.1 - 6.5e-10 38.6 0.0 5.4e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_syn_2C PF08485.10 KIR65979.1 - 2.8e-08 33.3 0.0 5.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein C-terminal NmrA PF05368.13 KIR65979.1 - 3.3e-08 33.4 0.1 4.1e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KIR65979.1 - 2.2e-07 30.9 0.1 3.9e-07 30.2 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KIR65979.1 - 5.8e-07 28.9 2.1 0.071 12.3 0.0 3.1 2 1 1 3 3 3 3 Male sterility protein adh_short PF00106.25 KIR65979.1 - 1.9e-05 24.2 0.3 4.8e-05 22.9 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR65979.1 - 4e-05 23.3 0.8 4e-05 23.3 0.8 1.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GPP34 PF05719.11 KIR65979.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.5 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) NAD_Gly3P_dh_N PF01210.23 KIR65979.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KIR65979.1 - 0.026 15.1 0.0 0.077 13.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIR65979.1 - 0.063 13.4 0.1 0.77 9.9 0.0 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIR65979.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Acetyltransf_1 PF00583.25 KIR65980.1 - 4.5e-12 46.2 0.0 8.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIR65980.1 - 2.4e-06 27.4 0.0 6.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KIR65980.1 - 9.2e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR65980.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR65980.1 - 0.00061 20.0 0.3 0.00061 20.0 0.3 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIR65980.1 - 0.018 15.1 0.0 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Lactamase_B_2 PF12706.7 KIR65981.1 - 7.6e-53 179.0 2.1 1e-52 178.6 2.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIR65981.1 - 3.6e-20 72.5 0.0 4.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIR65981.1 - 0.09 12.8 6.6 0.58 10.1 6.6 2.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KIR65981.1 - 0.17 11.3 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain ADH_N PF08240.12 KIR65982.1 - 2.9e-27 94.7 0.1 4.9e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KIR65982.1 - 4.2e-15 55.4 0.4 9.3e-15 54.2 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KIR65982.1 - 1.2e-13 51.2 1.7 7e-10 39.0 0.1 2.5 2 1 1 3 3 3 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIR65982.1 - 0.057 12.8 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer2_3 PF13085.6 KIR65983.1 - 3.2e-25 88.2 0.4 2.1e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 KIR65983.1 - 1e-10 41.9 1.5 1e-10 41.9 1.5 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR65983.1 - 1.3e-09 38.5 4.0 1.3e-09 38.5 4.0 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KIR65983.1 - 3.3e-09 37.1 8.5 5.5e-08 33.2 1.0 2.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIR65983.1 - 3.2e-07 30.3 6.2 3.2e-07 30.3 6.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIR65983.1 - 3.9e-07 30.1 7.3 5.3e-05 23.3 0.1 2.8 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KIR65983.1 - 2.1e-06 27.9 0.6 0.074 13.3 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KIR65983.1 - 6e-06 25.9 3.8 6e-06 25.9 3.8 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 KIR65983.1 - 6.5e-06 26.0 1.1 6.5e-06 26.0 1.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KIR65983.1 - 4.3e-05 24.3 1.5 0.022 15.6 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KIR65983.1 - 6.6e-05 23.1 1.0 6.6e-05 23.1 1.0 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KIR65983.1 - 0.0001 22.1 3.0 0.0001 22.1 3.0 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_3 PF12798.7 KIR65983.1 - 0.00074 20.3 22.2 0.0035 18.2 6.3 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer2 PF00111.27 KIR65983.1 - 0.00078 19.3 4.0 0.0012 18.8 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 KIR65983.1 - 0.0024 18.0 8.4 0.048 13.8 8.4 2.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR65983.1 - 0.0064 17.4 10.1 0.014 16.3 0.4 2.6 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 KIR65983.1 - 0.0094 16.7 3.6 0.1 13.3 0.9 2.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 KIR65983.1 - 0.69 10.5 12.3 0.63 10.6 4.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I FAD_binding_2 PF00890.24 KIR65984.1 - 2.5e-57 194.8 1.1 2.5e-57 194.8 1.1 1.5 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIR65984.1 - 5.3e-38 129.9 0.0 9.6e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KIR65984.1 - 6.3e-05 22.3 1.2 0.0091 15.3 0.6 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR65984.1 - 9.6e-05 22.1 2.9 0.0021 17.7 2.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR65984.1 - 0.002 18.3 0.7 0.01 16.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIR65984.1 - 0.0033 16.6 1.6 0.007 15.5 0.5 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIR65984.1 - 0.026 13.8 0.4 0.044 13.0 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KIR65984.1 - 0.092 11.4 0.2 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein YjeF_N PF03853.15 KIR65984.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus LysR_substrate PF03466.20 KIR65985.1 - 2.9e-45 154.2 10.5 4.1e-45 153.7 10.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 KIR65985.1 - 8.2e-23 80.1 4.0 1e-22 79.8 0.8 2.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 KIR65985.1 - 0.0095 15.7 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 KIR65985.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain RE_TdeIII PF09520.10 KIR65985.1 - 0.34 10.5 0.0 0.46 10.1 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DUF3418 PF11898.8 KIR65986.1 - 5.1e-241 801.4 2.2 8.7e-241 800.7 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) HA2 PF04408.23 KIR65986.1 - 4.7e-19 68.7 0.0 1.4e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIR65986.1 - 2.6e-18 66.1 0.0 5.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIR65986.1 - 1e-09 38.7 0.0 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIR65986.1 - 1.9e-06 27.8 0.2 7.6e-06 25.8 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIR65986.1 - 0.0001 22.6 0.1 0.00039 20.7 0.1 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIR65986.1 - 0.00026 20.1 0.0 0.00054 19.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KIR65986.1 - 0.00035 20.9 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KIR65986.1 - 0.0013 18.7 0.2 0.004 17.1 0.2 1.8 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KIR65986.1 - 0.0062 16.3 3.3 0.02 14.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIR65986.1 - 0.0073 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KIR65986.1 - 0.089 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KIR65986.1 - 0.2 11.3 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KIR65986.1 - 0.77 9.3 5.4 1.3 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain dCMP_cyt_deam_1 PF00383.23 KIR65987.1 - 9.7e-08 31.8 0.1 1.2e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KIR65987.1 - 0.011 15.4 1.4 1 9.0 0.2 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Cu-oxidase_2 PF07731.14 KIR65988.1 - 7.2e-23 80.8 0.1 1.5e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIR65988.1 - 1.1e-06 28.7 0.3 0.15 12.1 0.0 3.8 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 KIR65988.1 - 0.03 14.5 0.0 0.15 12.1 0.0 2.1 2 1 0 2 2 2 0 Multicopper oxidase TAT_signal PF10518.9 KIR65988.1 - 0.55 10.2 8.0 1.2 9.1 7.1 2.2 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence FecCD PF01032.18 KIR65989.1 - 5.4e-85 285.1 32.1 6.4e-85 284.9 32.1 1.0 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 KIR65990.1 - 3.2e-30 105.4 0.0 4.1e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR65990.1 - 8.2e-09 35.7 0.0 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR65990.1 - 4.1e-06 26.4 0.0 0.026 14.0 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR65990.1 - 4e-05 23.3 0.1 8.4e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR65990.1 - 4.9e-05 23.8 0.9 0.00012 22.5 0.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 KIR65990.1 - 0.00034 19.5 0.1 0.019 13.8 0.0 2.3 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 KIR65990.1 - 0.00043 20.1 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIR65990.1 - 0.00093 19.0 0.3 0.0022 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR65990.1 - 0.001 19.6 0.0 0.0014 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 KIR65990.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR65990.1 - 0.0082 16.4 0.1 0.024 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR65990.1 - 0.0085 16.3 0.1 0.031 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KIR65990.1 - 0.012 15.4 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 KIR65990.1 - 0.017 14.7 2.8 0.045 13.3 2.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIR65990.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain Adeno_IVa2 PF02456.15 KIR65990.1 - 0.042 12.6 0.1 0.076 11.8 0.0 1.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 KIR65990.1 - 0.049 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KIR65990.1 - 0.051 13.8 0.0 0.072 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR65990.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 KIR65990.1 - 0.065 13.3 0.0 0.23 11.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KIR65990.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KIR65990.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MutS_V PF00488.21 KIR65990.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 MutS domain V RNA_helicase PF00910.22 KIR65990.1 - 0.23 11.8 0.0 0.59 10.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Peripla_BP_2 PF01497.18 KIR65991.1 - 4.9e-28 98.3 0.3 6.9e-28 97.8 0.3 1.2 1 0 0 1 1 1 1 Periplasmic binding protein MTES_1575 PF18741.1 KIR65992.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 KIR65992.1 - 0.0057 16.5 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) DUF3516 PF12029.8 KIR65994.1 - 1.2e-219 730.1 1.1 1.5e-219 729.7 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) DEAD PF00270.29 KIR65994.1 - 3e-12 46.7 0.0 8.8e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR65994.1 - 2.2e-06 28.0 0.0 4.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR65994.1 - 0.00031 20.8 0.0 0.001 19.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RecO_N PF11967.8 KIR65994.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Recombination protein O N terminal IstB_IS21 PF01695.17 KIR65994.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3638 PF12340.8 KIR65994.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Methyltransf_4 PF02390.17 KIR65995.1 - 3e-49 166.8 0.0 3.5e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIR65995.1 - 5.7e-05 23.7 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR65995.1 - 0.0016 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR65995.1 - 0.0027 18.3 0.0 0.0062 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR65995.1 - 0.0033 18.1 0.0 0.021 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIR65995.1 - 0.024 15.7 0.1 0.086 13.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain NIR_SIR_ferr PF03460.17 KIR65995.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Glyoxalase_6 PF18029.1 KIR65996.1 - 1.3e-39 135.3 7.5 1e-20 74.5 0.4 2.0 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 KIR65996.1 - 0.00095 19.4 0.0 0.5 10.6 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TetR_C_1 PF02909.17 KIR65997.1 - 1.4e-10 41.2 0.1 2.6e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR65997.1 - 2.6e-08 33.5 0.0 2.6e-08 33.5 0.0 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family ABM PF03992.16 KIR65998.1 - 5.6e-19 68.0 0.1 7.8e-19 67.6 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Exo_endo_phos PF03372.23 KIR65999.1 - 4.4e-22 78.7 1.0 5.4e-22 78.5 1.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KIR65999.1 - 0.066 13.1 0.0 0.47 10.3 0.0 2.1 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase PAC2 PF09754.9 KIR66000.1 - 4.1e-47 161.0 0.0 5.3e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 PAC2 family EcsC PF12787.7 KIR66002.1 - 4e-12 46.3 0.6 8.7e-12 45.2 0.6 1.4 1 1 0 1 1 1 1 EcsC protein family DUF697 PF05128.12 KIR66002.1 - 0.00057 19.6 2.6 0.0012 18.6 2.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF697) Lipase_GDSL_2 PF13472.6 KIR66003.1 - 8.8e-19 68.6 0.2 1.5e-18 67.8 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR66003.1 - 1.1e-12 48.3 0.0 1.9e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Phage_holin_3_6 PF07332.11 KIR66004.1 - 0.00023 21.1 5.8 0.00025 21.1 5.8 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Sensor PF13796.6 KIR66004.1 - 0.0065 16.5 10.1 0.0081 16.2 10.1 1.1 1 0 0 1 1 1 1 Putative sensor DUF4191 PF13829.6 KIR66004.1 - 0.016 14.5 1.1 0.018 14.4 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.9 KIR66004.1 - 0.053 12.3 1.1 0.054 12.3 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VirB3 PF05101.13 KIR66004.1 - 0.058 13.6 3.4 0.078 13.2 3.4 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein FA_desaturase PF00487.24 KIR66004.1 - 0.16 11.8 2.9 0.16 11.8 2.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Aldedh PF00171.22 KIR66005.1 - 1.4e-142 475.5 0.1 1.5e-142 475.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIR66005.1 - 0.0035 16.4 0.2 0.013 14.6 0.2 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Bac_luciferase PF00296.20 KIR66006.1 - 2.6e-44 151.9 10.1 3.1e-44 151.7 10.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Na_H_Exchanger PF00999.21 KIR66007.1 - 2.5e-50 171.4 45.4 3.1e-50 171.1 45.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-UBP PF02148.19 KIR66008.1 - 1e-11 45.0 5.8 1.5e-11 44.5 5.8 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Glyco_hydro_9 PF00759.19 KIR66009.1 - 8e-100 335.1 7.3 1.3e-99 334.5 7.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CelD_N PF02927.14 KIR66009.1 - 2.8e-29 101.8 1.5 1.2e-28 99.8 0.1 2.7 3 0 0 3 3 3 1 Cellulase N-terminal ig-like domain CBM_2 PF00553.19 KIR66009.1 - 1.7e-25 89.3 8.1 6.4e-25 87.4 8.1 2.1 1 0 0 1 1 1 1 Cellulose binding domain CBM_4_9 PF02018.17 KIR66009.1 - 1.1e-15 58.1 0.2 6.1e-15 55.7 0.0 2.3 3 0 0 3 3 3 1 Carbohydrate binding domain Pec_lyase PF09492.10 KIR66009.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Pectic acid lyase CARDB PF07705.11 KIR66009.1 - 0.17 12.2 0.5 0.73 10.1 0.3 2.2 2 0 0 2 2 2 0 CARDB PP2C_2 PF13672.6 KIR66010.1 - 4.1e-13 49.5 2.1 7.9e-13 48.5 2.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KIR66010.1 - 2.2e-10 40.6 0.0 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KIR66010.1 - 0.001 19.0 2.2 0.0025 17.8 2.2 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HrpB_C PF08482.10 KIR66011.1 - 1.3e-53 180.9 0.0 2.3e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Helicase_C PF00271.31 KIR66011.1 - 2e-10 41.0 0.0 3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KIR66011.1 - 1.8e-07 31.4 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_30 PF13604.6 KIR66011.1 - 0.0033 17.1 1.2 0.0091 15.7 1.2 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KIR66011.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KIR66011.1 - 0.052 13.9 2.3 0.17 12.2 1.0 2.2 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 KIR66011.1 - 0.23 11.9 0.1 0.4 11.1 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF397 PF04149.12 KIR66012.1 - 1.2e-23 82.9 1.2 1.3e-23 82.7 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KIR66013.1 - 1.6e-14 54.0 1.7 1.6e-14 54.0 1.7 2.7 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR66013.1 - 2.5e-06 27.4 0.1 4.5e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66013.1 - 4.1e-06 26.7 0.1 9.2e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 KIR66013.1 - 0.00064 19.5 1.5 0.0011 18.8 0.3 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR66013.1 - 0.0031 17.4 1.5 0.02 14.8 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR66013.1 - 0.017 15.0 0.4 0.16 11.9 0.2 2.4 2 0 0 2 2 2 0 MarR family HTH_20 PF12840.7 KIR66013.1 - 0.025 14.6 0.6 0.025 14.6 0.6 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain GPP34 PF05719.11 KIR66014.1 - 3.2e-39 135.1 6.7 3.8e-39 134.8 6.7 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) AA_permease PF00324.21 KIR66015.1 - 1.7e-25 89.6 35.8 2.1e-25 89.3 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIR66015.1 - 1.9e-25 89.6 38.8 2.4e-25 89.3 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 KIR66016.1 - 2e-09 37.7 0.7 5.4e-09 36.3 0.7 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR66016.1 - 1e-08 35.5 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR66016.1 - 3.3e-08 33.5 0.0 5.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR66016.1 - 0.0003 20.9 0.0 0.0027 17.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Sigma70_r4 PF04545.16 KIR66017.1 - 4.2e-20 71.0 2.1 1.7e-18 65.9 0.9 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR66017.1 - 4.3e-17 61.6 0.0 7.8e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 KIR66017.1 - 1.4e-13 50.7 0.2 1.3e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 KIR66017.1 - 4.5e-11 42.2 0.2 4.5e-11 42.2 0.2 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 MarR_2 PF12802.7 KIR66017.1 - 2.1e-05 24.3 3.7 0.013 15.4 0.2 3.0 3 0 0 3 3 3 2 MarR family HTH_Crp_2 PF13545.6 KIR66017.1 - 9.3e-05 22.3 1.3 0.0029 17.5 0.1 2.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KIR66017.1 - 0.00032 20.4 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.22 KIR66017.1 - 0.00035 20.4 0.2 0.0016 18.3 0.1 2.0 2 0 0 2 2 2 1 MarR family GerE PF00196.19 KIR66017.1 - 0.0011 18.5 0.1 0.0046 16.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_3 PF01381.22 KIR66017.1 - 0.005 16.9 0.1 0.02 14.9 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_ECF PF07638.11 KIR66017.1 - 0.0077 16.1 0.1 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 ECF sigma factor HTH_AsnC-type PF13404.6 KIR66017.1 - 0.0082 16.0 0.1 6.5 6.7 0.0 3.1 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR66017.1 - 0.01 15.4 0.3 0.054 13.1 0.2 2.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 KIR66017.1 - 0.013 14.9 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF134 PF02001.16 KIR66017.1 - 0.014 15.9 0.0 0.028 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_10 PF04967.12 KIR66017.1 - 0.015 15.1 0.3 0.089 12.6 0.1 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_5 PF01022.20 KIR66017.1 - 0.025 14.5 0.1 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_38 PF13936.6 KIR66017.1 - 0.029 14.1 0.6 0.15 11.9 0.1 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 KIR66017.1 - 0.029 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Phage antitermination protein Q HTH_31 PF13560.6 KIR66017.1 - 0.033 14.5 0.5 0.033 14.5 0.5 2.6 3 0 0 3 3 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR66017.1 - 0.035 14.0 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_37 PF13744.6 KIR66017.1 - 0.036 14.0 0.4 0.16 12.0 0.2 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 KIR66017.1 - 0.058 13.5 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_IclR PF09339.10 KIR66017.1 - 2.2 8.1 5.3 2.9 7.8 0.1 3.1 4 0 0 4 4 3 0 IclR helix-turn-helix domain ADC PF06314.11 KIR66018.1 - 5.6e-07 29.4 0.5 8e-07 28.9 0.5 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) PLDc_2 PF13091.6 KIR66019.1 - 4e-11 42.9 0.0 3.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIR66019.1 - 2.6e-05 24.2 3.5 0.095 12.9 0.6 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif Pirin_C PF05726.13 KIR66020.1 - 5.6e-30 103.8 0.0 1.8e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 KIR66020.1 - 1.8e-29 101.9 0.8 3.9e-29 100.8 0.5 1.8 2 0 0 2 2 2 1 Pirin Cupin_2 PF07883.11 KIR66020.1 - 9e-05 22.1 2.4 0.11 12.2 0.0 2.9 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 KIR66020.1 - 0.07 12.7 0.2 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 Cupin DR2241 PF18069.1 KIR66020.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 DR2241 stabilising domain MarR_2 PF12802.7 KIR66021.1 - 6.3e-14 51.6 0.6 2.6e-12 46.5 0.1 2.3 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KIR66021.1 - 2.9e-10 39.9 0.0 5.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR66021.1 - 5.1e-05 23.7 0.0 9.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 KIR66021.1 - 0.015 15.6 0.0 0.028 14.8 0.0 1.5 1 1 0 1 1 1 0 Transcriptional regulator Acetyltransf_3 PF13302.7 KIR66022.1 - 6.3e-26 91.7 0.0 8.3e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR66022.1 - 1.5e-09 38.1 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR66022.1 - 0.15 11.8 3.5 1.5 8.5 3.5 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_3 PF01381.22 KIR66024.1 - 5.5e-06 26.4 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_28 PF13518.6 KIR66024.1 - 4.7e-05 23.4 0.1 0.00011 22.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR66024.1 - 7.7e-05 22.6 0.1 0.00016 21.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIR66024.1 - 8.4e-05 22.3 0.5 0.0002 21.1 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 KIR66024.1 - 0.00032 20.8 0.2 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_35 PF13693.6 KIR66024.1 - 0.0013 18.8 0.5 0.0044 17.0 0.5 1.9 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 KIR66024.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 KIR66024.1 - 0.0026 18.1 1.4 0.0026 18.1 1.4 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR66024.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_CI_repr PF07022.13 KIR66024.1 - 0.027 14.6 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR66024.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_26 PF13443.6 KIR66024.1 - 0.038 14.4 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.6 KIR66024.1 - 0.058 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_8 PF02954.19 KIR66024.1 - 0.11 12.3 0.6 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 KIR66024.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KIR66024.1 - 0.19 11.8 0.6 1.7 8.6 0.0 2.6 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KIR66024.1 - 0.21 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF397 PF04149.12 KIR66025.1 - 3.1e-21 75.2 0.7 4e-21 74.8 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) Gly-zipper_YMGG PF13441.6 KIR66026.1 - 3.6e-05 23.4 11.7 0.00013 21.6 11.6 2.1 1 1 0 1 1 1 1 YMGG-like Gly-zipper Romo1 PF10247.9 KIR66026.1 - 0.091 13.1 0.9 0.091 13.1 0.9 2.4 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 FA_desaturase PF00487.24 KIR66026.1 - 0.22 11.3 2.3 0.27 11.0 2.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Gly-zipper_OmpA PF13436.6 KIR66026.1 - 0.41 10.5 21.1 0.22 11.3 2.8 3.1 3 0 0 3 3 3 0 Glycine-zipper domain Gly-zipper_Omp PF13488.6 KIR66026.1 - 3 7.9 20.6 2.2 8.4 4.6 2.7 1 1 1 2 2 2 0 Glycine zipper DUF2207 PF09972.9 KIR66026.1 - 6.5 5.4 4.7 8.5 5.0 4.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2530 PF10745.9 KIR66026.1 - 7.3 6.9 12.2 9.5 6.5 11.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) Phage_holin_3_6 PF07332.11 KIR66026.1 - 8.8 6.4 12.8 12 6.0 12.8 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III adh_short_C2 PF13561.6 KIR66027.1 - 9.3e-64 215.2 0.1 1.1e-63 214.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66027.1 - 7.1e-49 165.9 0.0 8.3e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66027.1 - 1e-10 41.8 0.2 2.2e-10 40.8 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR66027.1 - 0.012 15.0 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_6 PF01341.17 KIR66028.1 - 1.1e-65 222.4 2.4 1.5e-65 222.0 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_2 PF00553.19 KIR66028.1 - 7.5e-23 80.8 6.2 2.1e-22 79.3 6.2 1.8 1 0 0 1 1 1 1 Cellulose binding domain HTH_3 PF01381.22 KIR66029.1 - 1.4e-14 53.9 0.2 2.3e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR66029.1 - 6.3e-14 52.1 5.7 1.4e-13 50.9 5.7 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 KIR66029.1 - 1.3e-12 47.2 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 KIR66029.1 - 1.6e-09 38.0 0.2 2.9e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 KIR66029.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR66029.1 - 0.00031 20.5 1.8 0.00055 19.8 1.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 KIR66029.1 - 0.0007 19.3 1.8 0.002 17.9 1.8 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 KIR66029.1 - 0.0022 17.8 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 KIR66029.1 - 0.0025 17.3 0.5 0.004 16.7 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Cupin_1 PF00190.22 KIR66029.1 - 0.0026 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KIR66029.1 - 0.0043 17.0 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Sigma70_r4 PF04545.16 KIR66029.1 - 0.025 14.1 2.1 0.086 12.4 1.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_37 PF13744.6 KIR66029.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_35 PF13693.6 KIR66029.1 - 0.069 13.2 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MerR PF00376.23 KIR66029.1 - 0.14 12.0 0.7 0.63 9.9 0.1 2.5 4 0 0 4 4 2 0 MerR family regulatory protein HTH_10 PF04967.12 KIR66029.1 - 0.15 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_AsnC-type PF13404.6 KIR66029.1 - 0.31 10.9 3.4 0.84 9.5 3.0 2.0 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain Amino_oxidase PF01593.24 KIR66030.1 - 2.6e-18 66.6 2.9 3.1e-10 40.0 0.2 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR66030.1 - 4.9e-15 55.5 0.5 1e-14 54.5 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR66030.1 - 2.2e-05 23.9 0.2 3.4e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR66030.1 - 5.6e-05 22.7 1.3 7.5e-05 22.2 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KIR66030.1 - 7.3e-05 22.5 5.3 7.3e-05 22.5 5.3 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR66030.1 - 0.0003 20.0 2.5 0.0003 20.0 2.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KIR66030.1 - 0.0016 19.0 0.2 0.0029 18.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR66030.1 - 0.0023 17.1 1.9 0.0031 16.7 1.9 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIR66030.1 - 0.0031 16.8 1.3 0.005 16.1 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIR66030.1 - 0.0042 15.8 1.0 0.006 15.3 1.0 1.1 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KIR66030.1 - 0.0087 15.4 1.9 0.014 14.7 1.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIR66030.1 - 0.017 14.4 1.7 0.023 13.9 1.7 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIR66030.1 - 0.02 14.2 0.3 0.032 13.5 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KIR66030.1 - 0.17 10.9 1.0 0.27 10.3 1.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Na_H_Exchanger PF00999.21 KIR66031.1 - 1.3e-37 129.5 28.2 1.5e-37 129.3 28.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ion_trans PF00520.31 KIR66031.1 - 0.06 12.6 1.2 0.14 11.4 1.2 1.6 1 0 0 1 1 1 0 Ion transport protein DUF2070 PF09843.9 KIR66031.1 - 0.49 8.6 2.4 0.8 7.9 2.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HAD_2 PF13419.6 KIR66032.1 - 1.1e-22 80.9 0.0 1.4e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIR66032.1 - 2.1e-19 70.7 0.2 2.8e-19 70.2 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR66032.1 - 1.2e-12 48.7 2.2 1.7e-12 48.2 2.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIR66032.1 - 3.9e-08 33.3 0.1 8.2e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIR66032.1 - 0.00055 20.0 0.0 0.26 11.4 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR66032.1 - 0.27 10.9 0.0 26 4.4 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase SpoIIE PF07228.12 KIR66033.1 - 3.1e-40 138.2 1.7 6.7e-40 137.1 1.7 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 KIR66033.1 - 1.2e-10 41.5 0.0 2.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 KIR66033.1 - 3.3e-05 24.1 0.2 0.00014 22.1 0.2 2.2 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 KIR66033.1 - 0.0049 17.5 0.3 0.26 11.9 0.1 2.6 2 0 0 2 2 2 1 GAF domain PAS_9 PF13426.7 KIR66033.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 PAS domain HATPase_c PF02518.26 KIR66033.1 - 0.021 15.3 0.0 0.054 14.0 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KIR66033.1 - 0.032 14.2 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 PAS domain sCache_3_3 PF17202.4 KIR66033.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Single cache domain 3 TM_helix PF05552.12 KIR66034.1 - 1.2e-17 63.6 13.6 6.9e-15 54.8 2.9 4.7 5 0 0 5 5 5 2 Conserved TM helix Colicin_V PF02674.16 KIR66034.1 - 0.31 11.0 22.6 0.22 11.5 0.4 3.2 2 1 1 3 3 3 0 Colicin V production protein DUF2070 PF09843.9 KIR66034.1 - 7.6 4.7 11.4 13 3.9 11.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) HemY_N PF07219.13 KIR66034.1 - 8.9 6.6 19.0 0.14 12.4 0.8 3.3 3 1 0 3 3 3 0 HemY protein N-terminus DUF3333 PF11812.8 KIR66035.1 - 0.037 14.2 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) DUF1110 PF06533.12 KIR66036.1 - 0.0011 19.0 0.5 0.0022 18.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1110) DUF4407 PF14362.6 KIR66037.1 - 0.08 12.3 3.1 0.094 12.1 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ODC_AZ PF02100.17 KIR66037.1 - 0.12 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Polyketide_cyc PF03364.20 KIR66039.1 - 1.1e-17 64.5 0.6 1.4e-17 64.2 0.6 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KIR66039.1 - 4.7e-08 33.4 2.9 5.9e-08 33.1 2.9 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2795 PF11387.8 KIR66040.1 - 4.3e-09 36.4 0.2 6.8e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) ChaB PF06150.12 KIR66041.1 - 3.3e-20 72.4 0.8 5.6e-20 71.7 0.8 1.4 1 0 0 1 1 1 1 ChaB Rho_N PF07498.12 KIR66041.1 - 2.5e-06 27.3 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Mso1_C PF14477.6 KIR66041.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 Aldedh PF00171.22 KIR66042.1 - 1.1e-125 419.8 1.5 1.2e-125 419.6 1.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIR66042.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glycos_transf_2 PF00535.26 KIR66043.1 - 5.3e-30 104.5 0.0 6.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66043.1 - 1.4e-14 54.5 0.0 1.7e-14 54.3 0.0 1.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIR66043.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Polyketide_cyc2 PF10604.9 KIR66044.1 - 8.1e-13 48.9 2.1 1e-12 48.5 2.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIR66044.1 - 2.5e-09 37.4 0.1 2.6e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 KIR66044.1 - 0.0039 17.4 0.4 0.0048 17.1 0.4 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glycos_transf_1 PF00534.20 KIR66045.1 - 6.9e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR66045.1 - 0.00028 21.3 0.1 0.00069 20.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIR66045.1 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 SIS_2 PF13580.6 KIR66046.1 - 3.6e-21 75.6 0.1 5.1e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 KIR66046.1 - 0.00056 19.8 0.1 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 SIS domain PfkB PF00294.24 KIR66047.1 - 6.9e-26 91.2 1.2 1.2e-25 90.5 1.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 KIR66047.1 - 3e-13 50.2 0.0 4.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 KIR66047.1 - 4.1e-05 23.1 0.2 4.1e-05 23.1 0.2 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase FAD_syn PF06574.12 KIR66047.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase adh_short PF00106.25 KIR66048.1 - 5.8e-36 123.8 2.3 2.2e-35 121.9 2.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR66048.1 - 1.1e-27 97.1 0.8 1.8e-27 96.4 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR66048.1 - 2.5e-06 27.5 3.7 0.0003 20.8 3.7 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR66048.1 - 2.1e-05 24.1 0.1 3.5e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KIR66048.1 - 0.28 11.0 1.4 1 9.1 0.8 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_9 PF01075.17 KIR66049.1 - 4e-28 98.4 0.0 6.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Topoisom_I PF01028.20 KIR66050.1 - 4.6e-28 98.0 0.0 5.8e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Glyco_hydro_19 PF00182.19 KIR66050.1 - 0.014 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Chitinase class I HxlR PF01638.17 KIR66051.1 - 1.1e-22 79.7 0.0 2.3e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 HxlR-like helix-turn-helix HTH_20 PF12840.7 KIR66051.1 - 0.0054 16.8 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.14 KIR66051.1 - 0.0074 16.2 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 KIR66051.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 KIR66051.1 - 0.014 15.2 0.4 0.031 14.1 0.4 1.6 1 1 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 KIR66051.1 - 0.03 14.3 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Replic_Relax PF13814.6 KIR66051.1 - 0.032 14.3 0.1 0.045 13.8 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation GntR PF00392.21 KIR66051.1 - 0.11 12.2 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MerR PF00376.23 KIR66051.1 - 0.14 12.0 0.1 2.1 8.2 0.1 2.2 1 1 0 1 1 1 0 MerR family regulatory protein DUF2513 PF10711.9 KIR66051.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) Aldo_ket_red PF00248.21 KIR66052.1 - 5.1e-46 157.2 0.0 4.9e-44 150.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RsdA_SigD_bd PF16751.5 KIR66052.1 - 0.023 15.0 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region TetR_C_31 PF17940.1 KIR66053.1 - 0.038 14.2 4.5 0.027 14.7 2.8 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Helicase_C PF00271.31 KIR66054.1 - 5.9e-20 71.7 0.0 1.3e-17 64.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIR66054.1 - 8.8e-15 54.9 0.0 2.7e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KIR66054.1 - 3.6e-12 46.8 0.4 7e-12 45.9 0.4 1.4 1 0 0 1 1 1 1 RecQ zinc-binding DUF3553 PF12073.8 KIR66054.1 - 2.2e-06 27.3 0.0 4.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3553) ResIII PF04851.15 KIR66054.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KIR66054.1 - 0.0034 17.4 1.6 0.009 16.0 0.1 2.4 2 0 0 2 2 2 1 HRDC domain HEM4 PF02602.15 KIR66054.1 - 0.018 14.4 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD TrmB PF01978.19 KIR66054.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB AAA_30 PF13604.6 KIR66054.1 - 0.081 12.6 0.0 0.43 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Bac_luciferase PF00296.20 KIR66055.1 - 1.7e-50 172.2 6.3 3.8e-50 171.1 6.3 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase Acetyltransf_CG PF14542.6 KIR66056.1 - 2.3e-24 85.3 0.0 2.6e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KIR66056.1 - 4.8e-07 30.0 0.0 5.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 KIR66056.1 - 0.0053 16.9 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR66056.1 - 0.0056 17.1 0.0 0.006 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR66056.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR66056.1 - 0.044 13.8 0.0 0.066 13.3 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1206 PF06724.11 KIR66058.1 - 6.8e-56 186.3 36.5 2.2e-22 78.9 8.9 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) COX4_pro_2 PF07835.12 KIR66058.1 - 0.1 12.7 2.9 0.25 11.4 0.8 2.6 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2207 PF09972.9 KIR66058.1 - 0.14 10.9 1.4 2 7.1 0.1 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DctQ PF04290.12 KIR66058.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.6 2 1 2 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component Abhydrolase_9_N PF15420.6 KIR66058.1 - 0.67 9.9 11.0 0.36 10.8 4.0 2.9 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Phage_holin_3_6 PF07332.11 KIR66059.1 - 6.9e-34 116.3 15.0 7.9e-34 116.1 15.0 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KIR66059.1 - 0.017 13.9 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 KIR66059.1 - 0.047 13.4 0.2 0.055 13.2 0.2 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 KIR66059.1 - 1.2 8.8 5.7 1.6 8.4 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3618 PF12277.8 KIR66060.1 - 1.3e-12 47.7 7.7 1.3e-12 47.7 7.7 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF3618) DotU PF09850.9 KIR66060.1 - 0.0053 16.5 2.8 0.0058 16.4 1.3 1.6 1 1 1 2 2 2 1 Type VI secretion system protein DotU DUF883 PF05957.13 KIR66060.1 - 0.0064 17.1 13.3 0.02 15.5 13.3 1.8 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KIR66060.1 - 0.015 15.2 6.7 0.023 14.6 6.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CagE_TrbE_VirB PF03135.14 KIR66060.1 - 0.15 12.1 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF4235 PF14019.6 KIR66061.1 - 7.5e-27 93.2 6.6 8.6e-27 93.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) CSD PF00313.22 KIR66062.1 - 1.4e-31 108.1 0.7 1.5e-31 108.0 0.7 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KIR66062.1 - 0.00045 19.9 0.2 0.00067 19.3 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 KIR66062.1 - 0.01 16.1 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 S1 RNA binding domain DUF202 PF02656.15 KIR66063.1 - 0.026 14.9 5.1 0.036 14.5 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) YtpI PF14007.6 KIR66063.1 - 0.028 14.5 2.0 0.44 10.7 1.9 2.0 1 1 0 1 1 1 0 YtpI-like protein DUF4199 PF13858.6 KIR66063.1 - 0.048 14.1 0.4 0.051 14.0 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PIRT PF15099.6 KIR66063.1 - 0.052 13.1 3.9 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family MerC PF03203.14 KIR66063.1 - 0.064 13.7 2.2 0.19 12.2 1.1 1.8 1 1 1 2 2 2 0 MerC mercury resistance protein Phage_holin_2_4 PF16082.5 KIR66063.1 - 0.076 12.8 3.3 0.11 12.2 3.3 1.3 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4307 PF14155.6 KIR66063.1 - 1.2 8.9 7.8 2.2 8.2 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) Trp_oprn_chp PF09534.10 KIR66063.1 - 2 8.2 8.2 0.97 9.2 2.4 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 KIR66063.1 - 3.3 7.3 6.5 6.1 6.5 6.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.21 KIR66064.1 - 3.3e-56 190.7 0.0 3.7e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_25 PF13649.6 KIR66065.1 - 4.5e-14 52.9 0.0 8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR66065.1 - 1.7e-12 47.4 0.0 2.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR66065.1 - 6.1e-11 42.8 0.0 9.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR66065.1 - 9.4e-09 35.2 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66065.1 - 2.5e-07 31.3 0.0 4.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR66065.1 - 3.3e-07 30.0 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIR66065.1 - 0.00027 20.9 0.0 0.00041 20.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIR66065.1 - 0.0048 17.0 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIR66065.1 - 0.0057 16.0 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KIR66065.1 - 0.0063 16.0 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 KIR66065.1 - 0.2 11.2 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW A_deaminase PF00962.22 KIR66066.1 - 1.7e-84 284.0 0.0 1.9e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Trans_reg_C PF00486.28 KIR66067.1 - 2.6e-26 91.5 0.1 5.6e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KIR66067.1 - 7e-24 84.2 0.1 9.3e-24 83.8 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain MarR_2 PF12802.7 KIR66067.1 - 0.029 14.3 0.8 0.081 12.8 0.1 2.2 2 0 0 2 2 2 0 MarR family TrkA_N PF02254.18 KIR66067.1 - 0.032 14.5 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ADP_ribosyl_GH PF03747.14 KIR66068.1 - 2.5e-45 155.5 12.1 3.1e-45 155.1 12.1 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase tRNA-synt_2b PF00587.25 KIR66069.1 - 1.9e-32 112.7 0.0 3.6e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIR66069.1 - 3e-19 69.0 0.1 5.9e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KIR66069.1 - 1.1e-13 51.0 0.0 2.5e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HIT PF01230.23 KIR66070.1 - 2.4e-14 53.8 0.0 3.4e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 KIR66070.1 - 2.8e-07 30.5 0.0 3.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 KIR66070.1 - 6.9e-05 23.3 0.0 9.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Aldo_ket_red PF00248.21 KIR66071.1 - 3.2e-54 184.1 0.0 3.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EFG_IV PF03764.18 KIR66072.1 - 9.9e-41 138.3 0.0 1.6e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 KIR66072.1 - 1.3e-35 122.7 0.0 1.9e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIR66072.1 - 3.6e-21 75.0 0.0 6.4e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIR66072.1 - 8e-21 73.9 0.0 1.3e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIR66072.1 - 6.5e-10 39.3 0.1 2.7e-09 37.3 0.1 2.2 2 0 0 2 2 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIR66072.1 - 5.9e-08 32.8 0.0 7.7e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 KIR66072.1 - 7.3e-05 22.2 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 KIR66072.1 - 9.5e-05 22.8 0.1 0.00025 21.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KIR66072.1 - 0.0006 20.3 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KIR66072.1 - 0.0014 18.8 0.2 0.0028 17.8 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KIR66072.1 - 0.0019 18.7 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR66072.1 - 0.0037 17.2 0.3 0.0079 16.1 0.3 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KIR66072.1 - 0.0038 16.9 0.2 0.0082 15.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRPRB PF09439.10 KIR66072.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 KIR66072.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIR66072.1 - 0.029 14.3 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIR66072.1 - 0.056 13.4 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KIR66072.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KIR66072.1 - 0.062 13.3 0.1 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 KIR66072.1 - 0.065 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KIR66072.1 - 0.086 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KIR66072.1 - 0.11 12.8 1.1 0.24 11.6 1.1 1.6 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KIR66072.1 - 0.14 11.7 1.1 2.7 7.5 0.1 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 KIR66072.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein PduV-EutP PF10662.9 KIR66072.1 - 0.19 11.4 0.1 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KIR66072.1 - 0.25 11.3 0.2 0.47 10.4 0.2 1.4 1 0 0 1 1 1 0 NACHT domain TetR_C_17 PF17922.1 KIR66072.1 - 0.25 11.5 0.0 33 4.7 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF815 PF05673.13 KIR66072.1 - 0.28 10.3 0.1 0.46 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CDP-OH_P_transf PF01066.21 KIR66073.1 - 6.1e-11 42.9 2.7 6.1e-11 42.9 2.7 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Lip_A_acyltrans PF03279.13 KIR66074.1 - 3.1e-54 184.2 0.0 3.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Glyco_trans_1_4 PF13692.6 KIR66075.1 - 4.4e-26 91.9 0.2 1.1e-24 87.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR66075.1 - 1.2e-25 90.5 1.1 1.9e-25 89.8 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIR66075.1 - 3.8e-19 68.8 0.0 6.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR66075.1 - 1.6e-16 61.2 6.5 1.6e-16 61.2 6.5 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIR66075.1 - 6.3e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR66075.1 - 1.3e-05 25.3 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like EutK_C PF16365.5 KIR66075.1 - 0.016 15.2 0.6 0.061 13.4 0.6 2.0 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus Nif11 PF07862.11 KIR66075.1 - 0.13 12.6 0.0 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 Nif11 domain Glyco_transf_5 PF08323.11 KIR66075.1 - 0.16 11.6 0.1 0.71 9.5 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Wzy_C_2 PF11846.8 KIR66076.1 - 0.021 14.7 1.0 0.032 14.2 1.0 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Tad PF13400.6 KIR66076.1 - 0.039 14.2 1.4 0.039 14.2 1.4 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like SOR_SNZ PF01680.17 KIR66077.1 - 1.4e-106 354.9 3.3 1.8e-106 354.5 3.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KIR66077.1 - 7.3e-10 38.6 6.4 7.3e-07 28.7 0.4 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KIR66077.1 - 2.7e-05 23.4 0.1 0.0091 15.1 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KIR66077.1 - 0.00016 21.0 2.2 0.0065 15.7 0.1 2.9 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KIR66077.1 - 0.00031 20.3 0.2 0.0038 16.7 0.0 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.15 KIR66077.1 - 0.0017 17.9 7.0 0.003 17.0 1.1 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.21 KIR66077.1 - 0.0021 17.3 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase DHO_dh PF01180.21 KIR66077.1 - 0.018 14.3 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KIR66077.1 - 0.02 14.0 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.18 KIR66077.1 - 0.059 12.4 0.1 0.059 12.4 0.1 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase SNO PF01174.19 KIR66078.1 - 1.1e-55 188.4 0.0 1.3e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIR66078.1 - 2.2e-09 37.2 0.0 5.4e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KIR66078.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KIR66078.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KIR66078.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 DJ-1/PfpI family Transcrip_reg PF01709.20 KIR66079.1 - 9.4e-91 303.5 0.1 1.1e-90 303.3 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF2628 PF10947.8 KIR66080.1 - 0.04 14.3 0.1 0.04 14.3 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2628) PadR PF03551.14 KIR66081.1 - 2.4e-18 65.9 0.0 3.5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HxlR PF01638.17 KIR66081.1 - 0.0032 17.3 0.2 0.092 12.6 0.0 2.1 1 1 1 2 2 2 1 HxlR-like helix-turn-helix HTH_27 PF13463.6 KIR66081.1 - 0.022 15.3 0.0 0.079 13.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain MCPVI PF02993.14 KIR66082.1 - 1.9 8.2 7.1 3.4 7.5 7.1 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Neisseria_TspB PF05616.13 KIR66082.1 - 4.2 5.7 14.4 5.5 5.3 14.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF1205 PF06722.12 KIR66083.1 - 6.6e-23 80.6 0.2 1.7e-22 79.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1205) UDPGT PF00201.18 KIR66083.1 - 1.6e-07 30.5 0.0 8.5e-07 28.1 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIR66083.1 - 0.00053 20.0 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 KIR66083.1 - 0.27 11.2 3.2 0.5 10.4 0.2 2.7 2 2 0 2 2 2 0 Glycosyltransferase Family 4 DegT_DnrJ_EryC1 PF01041.17 KIR66084.1 - 1.8e-95 320.3 0.0 2.1e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KIR66084.1 - 0.0003 20.1 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIR66084.1 - 0.0062 15.1 0.0 0.0087 14.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIR66084.1 - 0.012 14.6 0.0 0.031 13.2 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V ATPgrasp_N PF18130.1 KIR66084.1 - 0.06 13.9 0.0 0.17 12.5 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp N-terminal domain RmlD_sub_bind PF04321.17 KIR66085.1 - 7.2e-44 150.0 0.0 8.6e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIR66085.1 - 5e-15 55.6 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR66085.1 - 3.7e-12 45.8 0.0 5.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIR66085.1 - 1e-10 41.5 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIR66085.1 - 4.4e-09 35.9 0.0 8.2e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KIR66085.1 - 7.8e-06 25.9 0.0 2.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KIR66085.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIR66085.1 - 1.7e-05 24.1 0.1 2.5e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KIR66085.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 KIR66086.1 - 1.3e-29 103.3 0.6 3.5e-25 88.7 1.5 3.0 2 1 0 2 2 2 2 Cytochrome P450 DUF1205 PF06722.12 KIR66087.1 - 1.4e-16 60.4 0.0 2.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1205) UDPGT PF00201.18 KIR66087.1 - 4.5e-05 22.4 0.0 6.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIR66087.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 KIR66087.1 - 0.00087 19.7 0.4 0.0048 17.3 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR66087.1 - 0.11 12.5 5.2 0.17 11.9 0.5 2.8 1 1 2 3 3 3 0 Glycosyltransferase Family 4 NAD_binding_2 PF03446.15 KIR66088.1 - 1.3e-36 126.2 1.4 1.9e-36 125.6 1.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIR66088.1 - 5.9e-15 55.6 0.2 1.3e-14 54.5 0.2 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KIR66088.1 - 4e-08 33.7 0.2 1e-07 32.4 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIR66088.1 - 8.4e-07 28.5 0.2 1.1e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KIR66088.1 - 2.9e-05 23.7 0.1 5.1e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KIR66088.1 - 0.00011 22.1 0.7 0.00021 21.2 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIR66088.1 - 0.00071 19.6 1.6 0.0044 17.0 0.5 2.3 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KIR66088.1 - 0.003 17.6 0.1 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIR66088.1 - 0.016 14.9 0.2 0.027 14.1 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DpaA_N PF16924.5 KIR66088.1 - 0.027 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain NAD_binding_8 PF13450.6 KIR66088.1 - 0.066 13.5 0.3 0.22 11.8 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 KIR66088.1 - 0.25 11.8 2.7 15 6.1 0.2 2.6 3 0 0 3 3 3 0 XdhC Rossmann domain zf-UBP PF02148.19 KIR66089.1 - 5.6e-12 45.8 5.7 7.2e-12 45.5 5.7 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Abhydrolase_6 PF12697.7 KIR66090.1 - 1.3e-17 65.2 14.3 1.5e-17 64.9 14.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR66090.1 - 2e-08 33.8 0.1 3.7e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIR66090.1 - 5.2e-06 26.3 0.4 7.6e-06 25.8 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR66090.1 - 7.8e-06 25.7 1.1 0.0026 17.4 0.2 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KIR66090.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 KIR66090.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KIR66090.1 - 0.17 11.6 0.3 0.34 10.6 0.3 1.4 1 0 0 1 1 1 0 PGAP1-like protein Acetyltransf_9 PF13527.7 KIR66091.1 - 1.6e-14 54.1 0.0 4.2e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR66091.1 - 1.8 8.7 8.9 0.5 10.5 1.0 3.1 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain FAA_hydrolase PF01557.18 KIR66092.1 - 2.3e-71 240.0 0.0 2.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 2-Hacid_dh_C PF02826.19 KIR66093.1 - 1.1e-45 155.2 0.0 1.9e-45 154.4 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIR66093.1 - 7e-11 41.9 0.0 9.2e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Epimerase PF01370.21 KIR66094.1 - 0.00027 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIR66094.1 - 0.00058 19.5 0.0 0.00089 18.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIR66094.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding BPD_transp_1 PF00528.22 KIR66095.1 - 7.8e-20 71.4 11.0 7.8e-20 71.4 11.0 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4389 PF14333.6 KIR66095.1 - 0.067 13.1 0.1 0.067 13.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) Popeye PF04831.13 KIR66095.1 - 9.8 6.3 8.1 1.1 9.4 1.9 2.2 2 0 0 2 2 2 0 Popeye protein conserved region BPD_transp_1 PF00528.22 KIR66096.1 - 1.5e-18 67.2 14.6 1.5e-18 67.2 14.6 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF997 PF06196.12 KIR66096.1 - 0.41 10.7 0.2 0.41 10.7 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF997) SBP_bac_1 PF01547.25 KIR66097.1 - 1.1e-33 117.6 13.1 1.5e-33 117.1 13.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR66097.1 - 1.3e-28 100.7 9.2 1.7e-28 100.3 9.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR66097.1 - 0.0025 17.3 0.1 0.18 11.1 0.1 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein GFO_IDH_MocA PF01408.22 KIR66098.1 - 2.1e-21 76.9 0.2 3.7e-21 76.2 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR66098.1 - 6.4e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IclR PF01614.18 KIR66099.1 - 8.7e-28 96.7 0.0 1.5e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR66099.1 - 1.2e-12 47.4 5.7 4.6e-12 45.5 0.3 3.4 3 1 0 3 3 3 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR66099.1 - 3.2e-05 23.7 0.9 0.00014 21.6 0.1 2.5 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 KIR66099.1 - 0.013 15.6 3.1 0.046 13.8 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2802 PF10975.8 KIR66099.1 - 0.015 15.4 1.7 0.45 10.7 0.0 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF2802) HTH_23 PF13384.6 KIR66099.1 - 0.022 14.6 3.0 0.048 13.5 0.0 3.0 4 0 0 4 4 4 0 Homeodomain-like domain HTH_38 PF13936.6 KIR66099.1 - 0.023 14.5 1.4 13 5.7 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_29 PF13551.6 KIR66099.1 - 0.041 13.9 0.7 0.23 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 KIR66099.1 - 0.1 12.0 0.1 0.4 10.1 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TrmB PF01978.19 KIR66099.1 - 0.19 11.7 0.0 2.9 7.8 0.0 2.5 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_AraC PF00165.23 KIR66099.1 - 0.19 11.9 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DprA_WH PF17782.1 KIR66099.1 - 0.29 11.3 3.4 3.1 8.0 0.3 3.3 3 0 0 3 3 3 0 DprA winged helix domain HTH_18 PF12833.7 KIR66099.1 - 0.41 10.9 1.8 0.9 9.9 0.0 2.3 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR66099.1 - 1.2 9.0 5.0 1.5 8.7 0.1 3.3 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain HTH_31 PF13560.6 KIR66099.1 - 8.7 6.8 11.4 1.8 9.0 0.4 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain Aminotran_3 PF00202.21 KIR66100.1 - 3.7e-55 187.2 0.0 4.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIR66100.1 - 0.0057 15.9 0.0 0.023 13.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II MR_MLE_C PF13378.6 KIR66101.1 - 9.8e-60 201.8 0.8 1.5e-59 201.3 0.8 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR66101.1 - 2.5e-12 47.0 0.0 8.3e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Amidohydro_2 PF04909.14 KIR66102.1 - 6.7e-32 111.4 7.9 7.4e-32 111.3 7.9 1.0 1 0 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.6 KIR66103.1 - 3.1e-59 200.4 1.9 3.6e-59 200.2 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66103.1 - 1.5e-55 187.7 0.1 1.8e-55 187.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66103.1 - 3e-15 56.6 0.7 4.1e-15 56.2 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR66103.1 - 0.013 15.0 0.3 0.1 12.0 0.3 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMN_red PF03358.15 KIR66104.1 - 2.6e-14 53.3 0.0 4.2e-14 52.6 0.0 1.4 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIR66104.1 - 6.8e-05 22.7 0.0 8.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Thioredoxin_3 PF13192.6 KIR66105.1 - 0.18 11.9 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin domain Omp_AT PF11557.8 KIR66105.1 - 0.19 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain CMD PF02627.20 KIR66106.1 - 1.2e-20 73.3 0.1 1.6e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family UDPGT PF00201.18 KIR66107.1 - 2.7e-13 49.5 0.0 4.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIR66107.1 - 7.6e-08 32.5 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KIR66107.1 - 0.0027 17.0 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 AbfB PF05270.13 KIR66108.1 - 1.9e-47 160.8 2.2 4.2e-44 149.9 1.7 2.4 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) domain YpM PF09144.10 KIR66108.1 - 0.01 16.0 0.1 0.22 11.7 0.0 2.5 2 0 0 2 2 2 0 Yersinia pseudo-tuberculosis mitogen Glyco_hydro_43 PF04616.14 KIR66109.1 - 2.4e-40 138.7 6.8 3.8e-40 138.0 6.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RicinB_lectin_2 PF14200.6 KIR66109.1 - 4.5e-32 110.6 27.4 7.3e-22 77.9 5.5 4.4 4 1 1 5 5 5 2 Ricin-type beta-trefoil lectin domain-like GH43_C2 PF17851.1 KIR66109.1 - 1.9e-28 99.6 2.8 2e-28 99.5 0.1 2.4 3 0 0 3 3 3 1 Beta xylosidase C-terminal Concanavalin A-like domain Ricin_B_lectin PF00652.22 KIR66109.1 - 7.4e-14 52.1 2.6 1.5e-13 51.1 2.2 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain PAS_7 PF12860.7 KIR66109.1 - 0.0006 20.0 0.0 1.7 8.8 0.0 3.3 1 1 2 3 3 3 2 PAS fold adh_short_C2 PF13561.6 KIR66110.1 - 7.2e-60 202.5 0.3 8.7e-60 202.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66110.1 - 1.7e-54 184.3 0.0 2e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66110.1 - 1.8e-12 47.5 0.2 2.5e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR66110.1 - 0.0025 17.3 0.3 0.0094 15.4 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIR66110.1 - 0.22 10.8 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_N PF08240.12 KIR66111.1 - 1.6e-32 111.6 0.6 3.6e-32 110.5 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR66111.1 - 6.7e-26 90.8 0.4 8.1e-25 87.3 0.2 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIR66111.1 - 8.6e-09 35.2 2.4 1.2e-08 34.7 2.4 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIR66111.1 - 2.1e-06 28.8 0.3 4.7e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KIR66111.1 - 0.00051 19.4 1.2 0.001 18.4 1.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIR66111.1 - 0.0027 17.0 2.3 0.0048 16.2 2.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KIR66111.1 - 0.005 16.9 0.5 0.0095 16.0 0.2 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 KIR66111.1 - 0.0091 16.5 0.4 0.0091 16.5 0.4 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR66111.1 - 0.027 13.7 0.2 0.039 13.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR66111.1 - 0.035 12.8 0.1 0.051 12.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 KIR66111.1 - 0.04 14.2 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIR66111.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain rhaM PF05336.13 KIR66112.1 - 2.9e-34 117.4 0.3 3.2e-34 117.2 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase MR_MLE_C PF13378.6 KIR66113.1 - 3.7e-60 203.2 2.4 6.1e-60 202.5 2.4 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR66113.1 - 2.9e-10 40.4 0.0 6.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF3025 PF11227.8 KIR66113.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) BPD_transp_2 PF02653.16 KIR66114.1 - 9.5e-42 143.0 45.6 9.5e-42 143.0 45.6 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 KIR66115.1 - 1e-42 145.9 0.0 3.5e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR66115.1 - 1.2e-06 28.6 0.2 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66115.1 - 7e-05 22.4 1.2 1.1 8.7 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR66115.1 - 0.0006 19.5 1.9 0.0079 15.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR66115.1 - 0.011 15.7 0.1 0.033 14.1 0.1 1.8 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KIR66115.1 - 0.011 15.8 0.1 0.062 13.4 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KIR66115.1 - 0.024 14.4 6.4 0.08 12.7 0.1 3.1 3 1 0 3 3 3 0 AAA domain HTH_39 PF14090.6 KIR66115.1 - 0.11 12.3 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain STAS PF01740.21 KIR66115.1 - 0.15 11.7 0.2 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 STAS domain Zeta_toxin PF06414.12 KIR66115.1 - 0.25 10.6 4.7 4.6 6.5 0.3 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 KIR66115.1 - 0.91 9.1 11.8 0.079 12.5 1.8 3.5 3 1 0 3 3 3 0 AAA domain Peripla_BP_4 PF13407.6 KIR66116.1 - 4e-51 174.1 0.4 4.8e-51 173.8 0.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KIR66116.1 - 1.6e-09 37.6 0.0 2.1e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_6 PF13458.6 KIR66116.1 - 9.4e-05 22.2 0.7 0.00025 20.8 0.4 1.8 1 1 1 2 2 2 2 Periplasmic binding protein Peripla_BP_3 PF13377.6 KIR66116.1 - 0.00088 19.6 0.0 0.0025 18.2 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain CytB6-F_Fe-S PF08802.10 KIR66116.1 - 0.52 10.4 2.1 1.1 9.3 2.1 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Alpha_L_fucos PF01120.17 KIR66117.1 - 9.2e-89 298.3 1.6 1.3e-88 297.8 1.6 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase RicinB_lectin_2 PF14200.6 KIR66117.1 - 2.3e-24 86.0 29.0 8.3e-11 42.5 3.0 4.0 2 1 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66117.1 - 3.3e-09 37.1 3.8 9.6e-09 35.6 2.6 2.4 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Fucosidase_C PF16757.5 KIR66117.1 - 3.2e-05 24.4 0.0 7.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Crystall PF00030.19 KIR66117.1 - 5.1e-05 23.4 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin TAT_signal PF10518.9 KIR66117.1 - 6.8e-05 22.5 3.9 0.00016 21.3 3.9 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence DUF1464 PF07318.12 KIR66117.1 - 0.042 13.0 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) CytB6-F_Fe-S PF08802.10 KIR66117.1 - 0.35 10.9 1.6 0.75 9.9 0.9 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit AbfB PF05270.13 KIR66119.1 - 1.2e-44 151.7 1.4 1.1e-39 135.6 0.3 2.5 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) domain Glyco_hydro_43 PF04616.14 KIR66119.1 - 2.7e-07 30.2 1.6 6.4e-07 29.0 1.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 HisKA_3 PF07730.13 KIR66120.1 - 1.2e-15 57.8 7.1 5.5e-15 55.6 7.1 2.2 1 0 0 1 1 1 1 Histidine kinase Response_reg PF00072.24 KIR66121.1 - 2.2e-25 89.0 0.0 3.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR66121.1 - 7.1e-18 63.9 0.0 1.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR66121.1 - 1.5e-09 37.4 0.0 2.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66121.1 - 7.7e-06 25.3 0.0 1.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR66121.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KIR66121.1 - 0.0051 16.6 1.3 0.16 11.8 0.0 2.6 3 0 0 3 3 3 1 HTH DNA binding domain MarR_2 PF12802.7 KIR66121.1 - 0.0057 16.5 0.4 0.022 14.7 0.1 2.1 2 0 0 2 2 2 1 MarR family HTH_38 PF13936.6 KIR66121.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR66121.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 Homeodomain-like domain TadZ_N PF16968.5 KIR66121.1 - 0.052 13.2 1.5 0.097 12.4 0.3 2.2 2 1 0 2 2 2 0 Pilus assembly protein TadZ N-terminal ACR_tran PF00873.19 KIR66122.1 - 8.6e-215 715.6 30.7 1.5e-166 555.9 20.4 2.0 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family MMPL PF03176.15 KIR66122.1 - 1.2e-12 47.4 59.5 1.5e-08 34.0 12.2 3.7 3 1 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 KIR66122.1 - 1e-05 25.0 41.2 0.00079 18.9 16.1 2.9 3 0 0 3 3 3 2 Protein export membrane protein HMA PF00403.26 KIR66122.1 - 0.00072 20.0 8.7 4.2 7.9 0.1 5.2 4 1 1 5 5 5 2 Heavy-metal-associated domain Alpha_L_fucos PF01120.17 KIR66123.1 - 6.9e-87 292.1 6.4 9.6e-87 291.7 6.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase RicinB_lectin_2 PF14200.6 KIR66123.1 - 2.4e-26 92.3 17.4 1.1e-16 61.3 3.5 3.2 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66123.1 - 8.8e-11 42.2 0.4 1.7e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Fucosidase_C PF16757.5 KIR66123.1 - 2.8e-05 24.6 0.0 7.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain MLTR_LBD PF17765.1 KIR66124.1 - 6.6e-45 153.2 6.3 6.6e-45 153.2 6.3 1.6 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KIR66124.1 - 3.6e-16 59.3 7.2 3.6e-16 59.3 7.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66124.1 - 3.2e-09 36.7 0.1 5.9e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR66124.1 - 0.00052 20.0 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR66124.1 - 0.0073 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain SGL PF08450.12 KIR66125.1 - 6.5e-09 35.7 0.0 0.0018 17.9 0.0 3.2 2 1 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region He_PIG PF05345.12 KIR66125.1 - 0.0014 18.7 1.1 0.0069 16.6 0.1 2.6 2 0 0 2 2 2 1 Putative Ig domain NHL PF01436.21 KIR66125.1 - 0.0035 17.3 0.1 0.15 12.1 0.0 3.2 3 0 0 3 3 3 1 NHL repeat SGL PF08450.12 KIR66126.1 - 1.2e-69 234.6 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Acetyltransf_1 PF00583.25 KIR66127.1 - 4.6e-14 52.6 0.0 5.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR66127.1 - 4.4e-10 39.6 0.0 5.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIR66127.1 - 7e-10 39.2 0.0 9.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KIR66127.1 - 0.005 16.6 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 KIR66127.1 - 0.0051 16.7 0.0 0.0091 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KIR66127.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KIR66127.1 - 0.065 13.9 0.0 0.086 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_10 PF00331.20 KIR66128.1 - 2.7e-65 220.6 0.0 3.8e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_2 PF00553.19 KIR66128.1 - 2.9e-20 72.5 9.1 8.3e-20 71.0 9.1 1.8 1 0 0 1 1 1 1 Cellulose binding domain MSA-2c PF12238.8 KIR66128.1 - 0.015 15.3 7.6 0.024 14.7 7.6 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c FtsK_SpoIIIE PF01580.18 KIR66129.1 - 9.4e-87 290.4 0.0 6e-47 160.0 0.0 5.2 4 1 1 5 5 5 4 FtsK/SpoIIIE family AAA_16 PF13191.6 KIR66129.1 - 8.8e-08 32.7 6.6 0.019 15.4 0.2 4.4 4 1 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.6 KIR66129.1 - 9.4e-07 29.2 0.2 0.0048 17.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KIR66129.1 - 0.00016 21.6 0.1 0.25 11.3 0.1 3.8 4 0 0 4 4 4 1 NACHT domain DUF87 PF01935.17 KIR66129.1 - 0.00023 21.3 5.2 0.2 11.7 0.3 3.1 3 0 0 3 3 3 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIR66129.1 - 0.0012 18.9 0.5 0.93 9.6 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 KIR66129.1 - 0.0017 17.2 0.4 0.6 8.8 0.1 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein AAA_29 PF13555.6 KIR66129.1 - 0.0018 18.0 3.1 0.84 9.4 0.3 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KIR66129.1 - 0.0018 18.6 0.0 21 5.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 KIR66129.1 - 0.0043 17.6 2.8 2.2 8.8 0.1 3.2 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.6 KIR66129.1 - 0.006 16.2 0.4 4.2 6.9 0.3 3.2 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KIR66129.1 - 0.006 16.3 0.1 4.5 6.9 0.1 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Roc PF08477.13 KIR66129.1 - 0.0061 16.8 0.1 3.2 8.0 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KIR66129.1 - 0.013 16.0 0.9 29 5.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KIR66129.1 - 0.015 15.6 0.2 3.5 8.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 KIR66129.1 - 0.027 13.4 1.0 0.67 8.8 0.1 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_21 PF13304.6 KIR66129.1 - 0.03 14.1 0.2 0.82 9.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KIR66129.1 - 0.053 13.7 0.0 3.5 7.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 KIR66129.1 - 0.058 12.4 0.6 4.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.7 KIR66129.1 - 0.1 11.5 0.4 4.7 6.0 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.6 KIR66129.1 - 0.11 13.0 0.1 27 5.2 0.1 2.7 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 KIR66129.1 - 0.26 11.2 0.7 56 3.6 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KIR66129.1 - 0.27 11.0 0.1 11 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain YukD PF08817.10 KIR66130.1 - 4.8e-17 62.4 0.9 1.9e-16 60.5 0.9 2.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD T7SS_ESX1_EccB PF05108.13 KIR66131.1 - 5.8e-84 282.4 7.3 6.6e-84 282.2 7.3 1.0 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B WXG100 PF06013.12 KIR66132.1 - 1.2e-07 31.9 5.4 1.6e-07 31.4 5.4 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG HiaBD2 PF15403.6 KIR66132.1 - 0.02 15.3 0.6 0.15 12.5 0.0 2.1 1 1 1 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) WXG100 PF06013.12 KIR66133.1 - 2.4e-12 46.9 0.7 2.6e-12 46.8 0.7 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 KIR66133.1 - 0.0057 17.1 1.0 0.0069 16.8 1.0 1.1 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm Apolipoprotein PF01442.18 KIR66133.1 - 0.018 15.0 0.2 0.022 14.7 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain QIL1 PF15884.5 KIR66133.1 - 0.037 14.6 0.0 0.048 14.3 0.0 1.2 1 0 0 1 1 1 0 MICOS complex subunit MIC13, QIL1 DUF1640 PF07798.11 KIR66133.1 - 0.054 13.5 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) HsbA PF12296.8 KIR66133.1 - 0.059 13.8 2.2 0.076 13.5 2.2 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DASH_Duo1 PF08651.10 KIR66133.1 - 0.063 13.1 0.4 2.8 7.8 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 CBP PF12192.8 KIR66133.1 - 0.11 12.7 0.3 0.23 11.7 0.3 1.7 1 1 0 1 1 1 0 Fungal calcium binding protein Baculo_PEP_C PF04513.12 KIR66134.1 - 0.011 15.8 0.4 0.016 15.2 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF240 PF03086.14 KIR66134.1 - 0.13 12.1 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF240) YbaB_DNA_bd PF02575.16 KIR66135.1 - 2.4e-07 30.9 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Gln_amidase PF15644.6 KIR66137.1 - 2.6e-10 41.3 0.6 4.3e-05 24.5 0.3 4.1 2 0 0 2 2 2 2 Papain fold toxin 1, glutamine deamidase ThuA PF06283.11 KIR66141.1 - 1.1e-38 133.6 0.1 1.2e-38 133.4 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation GFO_IDH_MocA PF01408.22 KIR66142.1 - 3.1e-16 60.3 0.2 5e-16 59.6 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KIR66142.1 - 1.3e-05 25.8 1.0 4e-05 24.3 0.7 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIR66142.1 - 0.028 14.7 0.2 0.077 13.3 0.2 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 KIR66142.1 - 0.19 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KIR66143.1 - 2.6e-16 59.8 0.5 1.1e-15 57.8 0.5 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR66143.1 - 2.3e-09 36.9 0.3 0.00046 19.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR66143.1 - 1.4e-07 31.4 6.9 9.9e-06 25.4 1.8 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR66143.1 - 2.2e-06 27.8 0.8 7.1e-06 26.2 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIR66143.1 - 4.9e-05 22.8 0.1 0.1 11.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIR66143.1 - 7.4e-05 22.1 0.0 0.059 12.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR66143.1 - 0.0011 18.1 3.3 0.0016 17.6 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KIR66143.1 - 0.0065 15.6 0.4 0.027 13.5 0.4 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KIR66143.1 - 0.024 13.4 0.2 0.35 9.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KIR66143.1 - 0.045 13.8 0.7 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KIR66143.1 - 0.065 12.5 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KIR66143.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KIR66143.1 - 0.41 9.9 1.6 0.9 8.8 1.6 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TetR_N PF00440.23 KIR66144.1 - 9.7e-08 31.7 0.5 2.3e-07 30.5 0.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 KIR66144.1 - 0.21 11.9 11.1 0.06 13.7 7.6 1.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_25 PF13649.6 KIR66145.1 - 1.8e-12 47.8 0.2 3.2e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR66145.1 - 5e-12 45.9 0.0 6.5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66145.1 - 2e-09 38.1 0.1 3.7e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR66145.1 - 5.7e-09 36.0 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR66145.1 - 1e-08 34.9 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KIR66145.1 - 1.6e-07 31.9 0.1 2.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KIR66145.1 - 0.00015 22.7 1.1 0.00028 21.8 1.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIR66145.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KIR66145.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 KIR66145.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIR66145.1 - 0.015 14.6 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KIR66145.1 - 0.058 12.8 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Response_reg PF00072.24 KIR66146.1 - 1.1e-26 93.1 0.1 1.8e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR66146.1 - 2.9e-21 75.3 0.4 7.7e-21 74.0 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal ABC_tran PF00005.27 KIR66147.1 - 7.6e-32 110.7 0.0 1e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR66147.1 - 1.2e-05 24.9 0.0 0.034 13.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIR66147.1 - 7.1e-05 22.8 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR66147.1 - 0.00024 20.8 0.1 0.00049 19.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR66147.1 - 0.0012 19.2 1.1 0.0023 18.3 1.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR66147.1 - 0.0059 16.9 0.2 0.012 15.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR66147.1 - 0.0087 15.8 1.0 0.096 12.4 1.4 2.1 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIR66147.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MobB PF03205.14 KIR66147.1 - 0.017 15.0 0.3 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 KIR66147.1 - 0.026 14.1 0.6 0.079 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR66147.1 - 0.033 14.3 1.5 0.083 13.1 1.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIR66147.1 - 0.033 14.7 0.1 0.051 14.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIR66147.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KIR66147.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KIR66147.1 - 0.2 11.4 0.2 0.68 9.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIR66147.1 - 0.21 11.2 0.4 1.2 8.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MacB_PCD PF12704.7 KIR66148.1 - 1.2e-13 51.8 2.6 1.2e-13 51.8 2.6 1.9 2 1 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 KIR66148.1 - 1.4e-11 44.7 1.5 1.4e-11 44.7 1.5 3.7 4 1 0 4 4 4 1 FtsX-like permease family Amidohydro_1 PF01979.20 KIR66149.1 - 2.9e-25 89.3 0.0 1.1e-12 48.0 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIR66149.1 - 9.1e-13 48.5 4.0 1.2e-08 34.9 0.1 3.0 2 1 0 3 3 3 2 Amidohydrolase family Uricase PF01014.18 KIR66150.1 - 1.3e-56 190.5 0.0 3.9e-30 104.8 0.0 2.0 2 0 0 2 2 2 2 Uricase DUF2379 PF09543.10 KIR66150.1 - 0.0062 16.7 0.7 0.067 13.4 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2379) Transthyretin PF00576.21 KIR66151.1 - 3.3e-30 105.0 0.0 3.8e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family OHCU_decarbox PF09349.10 KIR66152.1 - 8.3e-37 127.1 1.2 9.3e-37 126.9 1.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase XdhC_C PF13478.6 KIR66153.1 - 3.6e-39 134.1 0.3 5.8e-39 133.4 0.3 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 KIR66153.1 - 1.2e-32 111.9 16.7 5.6e-22 77.7 3.8 2.9 2 0 0 2 2 2 2 XdhC and CoxI family DUF5348 PF17295.2 KIR66153.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) FAD_binding_5 PF00941.21 KIR66154.1 - 2.1e-13 50.4 0.0 3.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C2 PF02738.18 KIR66155.1 - 5.4e-151 503.8 6.9 7.6e-151 503.3 6.9 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 KIR66155.1 - 1e-28 99.9 0.1 2.2e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KIR66155.1 - 4.2e-23 81.2 0.7 9.2e-23 80.1 0.7 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KIR66155.1 - 0.001 19.0 3.7 0.0014 18.5 2.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 KIR66155.1 - 0.0036 17.3 0.1 0.027 14.5 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r4_2 PF08281.12 KIR66157.1 - 1.2e-15 56.9 0.2 2e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR66157.1 - 1.5e-09 37.5 4.9 2e-09 37.1 4.0 1.8 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR66157.1 - 7e-07 28.7 0.3 7e-07 28.7 0.3 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Phage_antitermQ PF06530.12 KIR66157.1 - 7e-05 22.7 0.3 0.00012 22.0 0.3 1.4 1 1 0 1 1 1 1 Phage antitermination protein Q Sigma70_ECF PF07638.11 KIR66157.1 - 7.3e-05 22.7 4.4 0.00027 20.9 4.4 1.9 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 KIR66157.1 - 9.5e-05 22.1 0.2 9.5e-05 22.1 0.2 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Terminase_5 PF06056.12 KIR66157.1 - 0.0001 22.1 0.0 0.00031 20.6 0.0 1.9 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_ISL3 PF13542.6 KIR66157.1 - 0.0012 18.3 0.1 0.0049 16.2 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KIR66157.1 - 0.0014 18.7 0.3 0.0065 16.6 0.2 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 KIR66157.1 - 0.0022 17.8 0.6 0.0048 16.7 0.6 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GerE PF00196.19 KIR66157.1 - 0.0022 17.5 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_AsnC-type PF13404.6 KIR66157.1 - 0.004 16.9 0.1 0.016 15.0 0.1 2.0 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 KIR66157.1 - 0.0076 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_25 PF13649.6 KIR66157.1 - 0.024 15.3 0.1 0.056 14.1 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPR_12 PF13424.6 KIR66157.1 - 0.028 14.7 1.2 0.028 14.7 1.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIR66157.1 - 0.094 12.9 1.2 0.31 11.2 1.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIR66157.1 - 0.12 13.0 8.6 0.1 13.2 5.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_24 PF13412.6 KIR66157.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 KIR66157.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_14 PF13428.6 KIR66157.1 - 1.4 10.0 7.9 0.6 11.1 3.3 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat FAP PF07174.11 KIR66158.1 - 0.0026 17.3 15.7 0.0037 16.8 15.7 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) VirB8 PF04335.13 KIR66158.1 - 0.14 12.0 0.4 0.26 11.1 0.1 1.5 2 0 0 2 2 2 0 VirB8 protein DUF3040 PF11239.8 KIR66158.1 - 0.95 9.8 3.9 0.28 11.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) HMGL-like PF00682.19 KIR66159.1 - 3.9e-61 206.9 4.1 4.7e-61 206.7 4.1 1.1 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.11 KIR66159.1 - 1.4e-32 111.0 0.3 3.2e-32 109.8 0.3 1.7 1 0 0 1 1 1 1 DmpG-like communication domain AcetDehyd-dimer PF09290.11 KIR66160.1 - 8.4e-63 210.7 0.2 1.2e-62 210.2 0.2 1.2 1 0 0 1 1 1 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Semialdhyde_dh PF01118.24 KIR66160.1 - 5.4e-12 46.2 0.1 2.1e-11 44.3 0.0 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KIR66160.1 - 0.0006 20.6 0.0 0.0015 19.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KIR66160.1 - 0.0031 18.2 0.2 0.01 16.5 0.0 2.0 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 KIR66160.1 - 0.0092 16.7 0.1 0.035 14.8 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Flagellin_IN PF07196.13 KIR66160.1 - 0.044 14.0 0.2 0.093 12.9 0.2 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif ABC_tran PF00005.27 KIR66162.1 - 1.2e-41 142.4 0.0 9.1e-20 71.6 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIR66162.1 - 2.3e-17 63.8 4.9 0.0028 17.5 0.0 4.1 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66162.1 - 3.2e-11 43.1 0.1 0.016 14.6 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KIR66162.1 - 2.8e-07 30.7 0.1 0.0057 16.9 0.0 2.9 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KIR66162.1 - 4.4e-07 30.6 0.1 0.054 14.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KIR66162.1 - 1.2e-06 28.2 0.1 0.01 15.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR66162.1 - 4.9e-05 23.3 0.0 0.068 13.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KIR66162.1 - 5.1e-05 23.1 4.1 0.016 14.9 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR66162.1 - 0.00018 21.9 15.6 0.041 14.3 0.3 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIR66162.1 - 0.00019 21.7 1.0 0.16 12.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran_Xtn PF12848.7 KIR66162.1 - 0.00023 21.1 5.1 0.00048 20.1 5.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 KIR66162.1 - 0.0016 18.9 0.4 4.4 7.7 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIR66162.1 - 0.0061 16.6 0.5 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KIR66162.1 - 0.012 15.7 9.7 0.92 9.7 0.1 3.7 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KIR66162.1 - 0.042 13.1 5.7 0.88 8.8 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 KIR66162.1 - 0.074 13.0 1.0 14 5.6 0.2 2.7 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.6 KIR66162.1 - 0.074 12.8 0.0 2.5 7.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KIR66162.1 - 0.075 12.6 1.9 4.6 6.8 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KIR66162.1 - 0.094 13.3 0.7 5.6 7.5 0.0 2.9 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 KIR66162.1 - 0.097 12.6 0.2 3 7.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KIR66162.1 - 0.11 12.0 4.9 4.7 6.7 0.0 3.6 3 1 0 3 3 3 0 AAA domain MCU PF04678.13 KIR66162.1 - 0.12 12.4 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Dynamin_N PF00350.23 KIR66162.1 - 0.16 12.0 0.5 6.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_28 PF13521.6 KIR66162.1 - 0.42 10.8 0.0 0.42 10.8 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_27 PF13514.6 KIR66162.1 - 0.49 9.9 7.1 1.7 8.2 0.0 3.3 3 1 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 KIR66162.1 - 0.51 10.0 7.1 4.3 7.0 0.0 3.3 3 1 0 3 3 3 0 Cytidylate kinase GrpE PF01025.19 KIR66162.1 - 0.58 9.8 3.7 0.95 9.1 3.7 1.2 1 0 0 1 1 1 0 GrpE Atg14 PF10186.9 KIR66162.1 - 0.85 8.6 4.7 1.2 8.1 4.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 KIR66162.1 - 4.1 4.8 23.5 0.24 8.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF3592 PF12158.8 KIR66164.1 - 0.057 13.5 0.9 0.15 12.1 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Peptidase_M48 PF01435.18 KIR66165.1 - 2.9e-13 50.0 0.0 6.8e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2336 PF10098.9 KIR66166.1 - 4.5e-10 39.4 30.6 2.6e-07 30.4 21.5 3.2 1 1 1 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2336) LRV PF01816.17 KIR66166.1 - 1.9e-09 37.3 72.7 0.00053 20.2 0.5 9.4 8 1 2 10 10 10 4 Leucine rich repeat variant HEAT_2 PF13646.6 KIR66166.1 - 0.0021 18.4 30.5 0.098 13.1 4.0 6.8 1 1 3 4 4 4 2 HEAT repeats HEAT PF02985.22 KIR66166.1 - 0.11 12.8 26.5 5.9 7.4 0.0 8.2 9 0 0 9 9 9 0 HEAT repeat RHH_6 PF16762.5 KIR66166.1 - 0.12 13.0 1.0 15 6.3 0.0 3.3 2 1 1 3 3 3 0 Ribbon-helix-helix domain GNAT_C PF18164.1 KIR66168.1 - 6.3e-43 146.1 0.0 1.6e-42 144.8 0.0 1.4 1 1 0 1 1 1 1 GNAT-like C-terminal domain DUF5596 PF18082.1 KIR66168.1 - 5.5e-20 71.0 0.6 1.1e-19 70.0 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5596) Bac_luciferase PF00296.20 KIR66169.1 - 3.5e-27 95.7 6.8 5.8e-27 94.9 6.8 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Aldo_ket_red PF00248.21 KIR66170.1 - 1.1e-52 179.1 0.0 1.4e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FtsX PF02687.21 KIR66171.1 - 4.6e-06 27.0 0.2 4.6e-06 27.0 0.2 4.5 3 1 1 4 4 4 2 FtsX-like permease family PadR PF03551.14 KIR66172.1 - 8.1e-17 61.0 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family DUF3375 PF11855.8 KIR66172.1 - 0.00072 18.6 0.8 0.00094 18.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) Vir_act_alpha_C PF10400.9 KIR66172.1 - 0.01 16.5 1.9 0.02 15.6 1.9 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term RTP PF02334.16 KIR66172.1 - 0.013 16.1 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 Replication terminator protein Replic_Relax PF13814.6 KIR66172.1 - 0.019 15.1 0.3 0.044 13.9 0.1 1.6 1 1 1 2 2 2 0 Replication-relaxation HTH_34 PF13601.6 KIR66172.1 - 0.05 13.8 0.0 0.092 12.9 0.0 1.6 1 1 0 1 1 1 0 Winged helix DNA-binding domain Mrr_N PF14338.6 KIR66172.1 - 0.062 13.4 0.0 1.7 8.8 0.0 2.9 2 1 0 2 2 2 0 Mrr N-terminal domain TrmB PF01978.19 KIR66172.1 - 0.11 12.4 0.2 0.51 10.3 0.0 2.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DUF2513 PF10711.9 KIR66172.1 - 0.18 12.1 0.0 0.62 10.4 0.0 1.8 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) DAO PF01266.24 KIR66173.1 - 4.9e-51 174.4 11.7 5.6e-51 174.2 11.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR66173.1 - 0.00032 20.7 1.6 0.026 14.5 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIR66173.1 - 0.00041 20.5 2.6 0.00041 20.5 2.6 2.4 3 1 0 3 3 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIR66173.1 - 0.0016 19.0 3.3 0.0023 18.5 2.3 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIR66173.1 - 0.0022 17.3 6.6 0.01 15.1 3.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIR66173.1 - 0.025 13.7 8.5 0.041 13.0 7.9 1.8 1 1 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KIR66173.1 - 0.028 14.9 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIR66173.1 - 0.034 14.0 1.9 0.052 13.4 1.9 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KIR66173.1 - 0.085 11.9 2.9 0.88 8.6 1.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 KIR66173.1 - 0.18 12.0 0.7 0.33 11.2 0.7 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KIR66173.1 - 0.2 10.5 2.5 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 KIR66173.1 - 0.25 11.3 0.9 0.41 10.6 0.9 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.7 KIR66173.1 - 0.26 10.6 1.8 0.27 10.5 0.9 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIR66173.1 - 0.27 10.8 0.8 0.4 10.2 0.8 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KIR66173.1 - 0.39 9.9 2.4 0.63 9.2 2.4 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KIR66173.1 - 0.4 9.9 5.1 0.72 9.1 5.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIR66173.1 - 1.9 7.1 3.4 2.5 6.7 2.4 1.6 2 0 0 2 2 2 0 HI0933-like protein GerE PF00196.19 KIR66174.1 - 1.8e-13 49.8 0.0 3.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_29 PF13551.6 KIR66174.1 - 0.00023 21.1 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KIR66174.1 - 0.006 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KIR66174.1 - 0.057 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain EutC PF05985.11 KIR66174.1 - 0.062 12.6 2.4 0.14 11.4 1.4 1.8 1 1 1 2 2 2 0 Ethanolamine ammonia-lyase light chain (EutC) PGP_phosphatase PF09419.10 KIR66174.1 - 0.089 12.4 0.4 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Beta_helix PF13229.6 KIR66175.1 - 3.6e-24 85.4 0.0 1e-12 48.2 0.0 3.5 1 1 1 3 3 3 3 Right handed beta helix region AAA PF00004.29 KIR66175.1 - 4.7e-17 62.7 0.0 7.4e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KIR66175.1 - 2.4e-14 53.3 1.6 1.5e-13 50.7 0.1 3.2 4 0 0 4 4 3 1 AAA lid domain AAA_16 PF13191.6 KIR66175.1 - 5.3e-07 30.2 2.1 0.015 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NosD PF05048.13 KIR66175.1 - 4.9e-06 26.0 0.0 4.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) AAA_5 PF07728.14 KIR66175.1 - 2e-05 24.6 0.2 0.005 16.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIR66175.1 - 3.5e-05 24.1 1.2 0.12 12.7 0.1 4.0 3 2 1 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KIR66175.1 - 0.00036 20.0 0.4 0.044 13.2 0.1 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KIR66175.1 - 0.00074 19.3 2.6 0.0039 16.9 0.4 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KIR66175.1 - 0.00093 19.1 0.3 0.094 12.6 0.1 2.6 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.12 KIR66175.1 - 0.0035 17.1 0.0 0.0093 15.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KIR66175.1 - 0.017 15.5 0.2 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR66175.1 - 0.052 13.7 0.4 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIR66175.1 - 0.078 13.5 0.1 0.44 11.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF1565 PF07602.11 KIR66175.1 - 0.083 12.2 0.2 0.21 10.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1565) DUF815 PF05673.13 KIR66175.1 - 0.25 10.5 0.1 3.2 6.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KIR66175.1 - 6.1 5.9 5.1 12 5.0 0.1 2.8 3 1 1 4 4 4 0 TIP49 P-loop domain GerE PF00196.19 KIR66177.1 - 5.9e-18 64.2 0.0 1e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 KIR66177.1 - 5.1e-16 58.8 0.0 7.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4 PF04545.16 KIR66177.1 - 7.6e-05 22.1 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIR66177.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 KIR66177.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR66177.1 - 0.028 14.0 0.0 0.084 12.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 KIR66177.1 - 0.038 14.5 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 KIR66177.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KIR66177.1 - 0.06 13.2 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KIR66177.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ART PF01129.18 KIR66179.1 - 8.5e-06 25.2 0.0 0.11 11.8 0.0 3.4 4 0 0 4 4 4 2 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 KIR66179.1 - 0.00021 20.7 0.0 0.56 9.5 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosyltransferase exoenzyme BLOC1_2 PF10046.9 KIR66179.1 - 0.028 14.7 0.0 15 6.0 0.0 4.0 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SCO1-SenC PF02630.14 KIR66179.1 - 0.039 13.9 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 SCO1/SenC DUF948 PF06103.11 KIR66179.1 - 8.6 6.7 11.9 7.3 6.9 0.1 5.3 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) T7SS_ESX_EspC PF10824.8 KIR66180.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm YbaB_DNA_bd PF02575.16 KIR66181.1 - 2.2e-09 37.4 0.0 2.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family WXG100 PF06013.12 KIR66182.1 - 1.7e-14 53.8 7.2 2.6e-14 53.2 7.2 1.3 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF5082 PF16888.5 KIR66182.1 - 0.0031 17.8 0.2 0.0037 17.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) RPN13_C PF16550.5 KIR66182.1 - 0.0032 17.6 1.1 0.0032 17.6 1.1 1.7 1 1 1 2 2 2 1 UCH-binding domain AATF-Che1 PF13339.6 KIR66182.1 - 0.03 15.0 1.1 0.56 10.9 1.1 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF2232 PF09991.9 KIR66182.1 - 0.03 13.5 0.3 0.036 13.2 0.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) ZapA PF05164.13 KIR66182.1 - 0.051 14.0 1.2 3.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Cell division protein ZapA FAP206 PF12018.8 KIR66182.1 - 0.052 13.1 0.2 0.058 12.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function GrpE PF01025.19 KIR66182.1 - 0.095 12.4 0.3 0.12 12.1 0.3 1.1 1 0 0 1 1 1 0 GrpE WXG100 PF06013.12 KIR66183.1 - 2e-10 40.7 6.6 2.3e-10 40.5 6.6 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG FeThRed_A PF02941.15 KIR66183.1 - 0.13 12.4 0.1 1.8 8.7 0.0 2.1 1 1 1 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain T7SS_ESX_EspC PF10824.8 KIR66183.1 - 0.16 12.4 6.1 0.21 12.1 6.1 1.1 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm FtsK_SpoIIIE PF01580.18 KIR66187.1 - 2.6e-91 305.3 0.0 5e-52 176.7 0.0 5.6 5 1 0 5 5 5 3 FtsK/SpoIIIE family AAA_16 PF13191.6 KIR66187.1 - 1e-11 45.5 2.2 0.021 15.2 0.2 3.8 3 0 0 3 3 3 3 AAA ATPase domain AAA_22 PF13401.6 KIR66187.1 - 1.3e-07 32.0 0.0 0.033 14.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 KIR66187.1 - 5.7e-06 26.4 0.0 0.3 11.0 0.0 4.0 3 2 0 3 3 3 2 NACHT domain DUF87 PF01935.17 KIR66187.1 - 2.2e-05 24.6 0.1 0.038 14.1 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_29 PF13555.6 KIR66187.1 - 6.9e-05 22.5 0.3 0.18 11.6 0.1 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIR66187.1 - 0.00014 21.9 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 KIR66187.1 - 0.0004 19.4 0.2 0.41 9.5 0.0 3.0 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 KIR66187.1 - 0.00075 19.9 0.0 0.28 11.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KIR66187.1 - 0.0025 18.0 0.3 5.5 7.1 0.0 3.6 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KIR66187.1 - 0.0038 17.6 0.0 15 6.0 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_10 PF12846.7 KIR66187.1 - 0.0039 16.2 0.0 2.2 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain ABC_tran PF00005.27 KIR66187.1 - 0.0053 17.3 0.4 1.8 9.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 KIR66187.1 - 0.011 14.9 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KIR66187.1 - 0.011 15.3 6.3 1 8.9 0.0 3.8 4 1 0 4 4 4 0 AAA domain Adeno_IVa2 PF02456.15 KIR66187.1 - 0.017 13.9 0.1 0.78 8.5 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein MID_pPIWI_RE PF18157.1 KIR66187.1 - 0.027 14.7 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 MID domain of pPIWI_RE AAA_18 PF13238.6 KIR66187.1 - 0.029 14.9 0.0 9.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIR66187.1 - 0.031 14.0 0.1 9.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 KIR66187.1 - 0.045 12.7 0.5 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF853 PF05872.12 KIR66187.1 - 0.067 11.8 0.1 0.23 10.0 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Zeta_toxin PF06414.12 KIR66187.1 - 0.099 11.9 1.2 13 5.0 0.1 3.5 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 KIR66187.1 - 0.18 11.2 0.7 1.4 8.3 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KIR66187.1 - 0.2 11.4 0.7 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system YukD PF08817.10 KIR66188.1 - 5.4e-15 55.8 1.5 9.9e-15 55.0 0.2 2.2 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD YbaB_DNA_bd PF02575.16 KIR66189.1 - 2.4e-21 75.8 0.0 2.9e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family AAA_19 PF13245.6 KIR66190.1 - 3e-12 47.1 0.0 8.3e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIR66190.1 - 3e-09 36.8 0.0 0.00035 20.2 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIR66190.1 - 5.8e-09 35.6 0.0 5.2e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KIR66190.1 - 1.3e-08 34.5 0.0 0.00079 18.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.18 KIR66190.1 - 1.4e-07 31.5 0.0 4.4e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIR66190.1 - 9.9e-06 25.4 0.0 0.0058 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KIR66190.1 - 7.3e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIR66190.1 - 0.00053 19.3 0.3 0.031 13.5 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KIR66190.1 - 0.0021 17.6 0.0 0.0073 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR66190.1 - 0.016 15.6 0.4 0.076 13.4 0.1 2.4 3 0 0 3 3 3 0 AAA ATPase domain DEAD PF00270.29 KIR66190.1 - 0.016 15.0 0.0 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase T2SSE PF00437.20 KIR66190.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C PF13361.6 KIR66190.1 - 0.083 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ATPase PF06745.13 KIR66190.1 - 0.11 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC S4 PF01479.25 KIR66190.1 - 0.15 11.8 0.9 0.49 10.2 0.4 2.0 2 0 0 2 2 2 0 S4 domain CBM_2 PF00553.19 KIR66191.1 - 1.8e-27 95.6 7.8 1.8e-27 95.6 7.8 2.0 2 0 0 2 2 2 1 Cellulose binding domain Esterase_phd PF10503.9 KIR66191.1 - 1.4e-22 80.3 1.0 1.4e-22 80.3 1.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR66191.1 - 2.7e-13 49.9 0.5 5.1e-13 49.0 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIR66191.1 - 0.0018 18.2 0.0 0.035 13.9 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KIR66191.1 - 0.0092 15.9 0.1 0.029 14.2 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KIR66191.1 - 0.011 15.4 4.0 0.074 12.7 2.9 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 KIR66191.1 - 0.013 15.2 0.6 0.027 14.1 0.6 1.4 1 1 0 1 1 1 0 Putative esterase CBP_BcsO PF17037.5 KIR66191.1 - 0.54 10.4 5.1 1 9.5 5.1 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO PaaX_C PF08223.11 KIR66192.1 - 6.8e-21 74.4 0.2 1.1e-20 73.7 0.2 1.3 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain PaaX PF07848.12 KIR66192.1 - 5.2e-14 52.2 2.1 5.2e-14 52.2 2.1 1.8 2 0 0 2 2 2 1 PaaX-like protein GntR PF00392.21 KIR66192.1 - 0.0042 16.7 0.6 0.01 15.5 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Penicillinase_R PF03965.16 KIR66192.1 - 0.032 14.6 0.0 0.074 13.4 0.0 1.5 2 0 0 2 2 2 0 Penicillinase repressor DUF1801 PF08818.11 KIR66193.1 - 0.00078 19.9 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DU1801) Glyco_hydro_10 PF00331.20 KIR66194.1 - 2.6e-104 348.8 0.0 3.1e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_2 PF00553.19 KIR66194.1 - 9.4e-18 64.4 10.7 3.5e-17 62.6 10.7 2.0 1 0 0 1 1 1 1 Cellulose binding domain Cellulase PF00150.18 KIR66194.1 - 0.0003 20.3 0.1 0.0028 17.1 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KIR66194.1 - 0.0083 15.5 0.0 0.069 12.5 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase Esterase_phd PF10503.9 KIR66195.1 - 1e-19 71.0 0.1 1.7e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_2 PF00553.19 KIR66195.1 - 3.2e-17 62.7 10.7 3.2e-17 62.7 10.7 2.2 2 0 0 2 2 2 1 Cellulose binding domain Peptidase_S9 PF00326.21 KIR66195.1 - 1.3e-07 31.4 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 KIR66195.1 - 0.0052 16.5 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 KIR66195.1 - 0.0053 16.7 0.0 0.0053 16.7 0.0 1.9 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3060 PF11259.8 KIR66195.1 - 0.012 15.3 0.0 6.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Abhydrolase_2 PF02230.16 KIR66195.1 - 0.018 14.9 0.3 0.04 13.7 0.1 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase CBM_2 PF00553.19 KIR66196.1 - 3.2e-17 62.7 10.7 3.2e-17 62.7 10.7 2.0 2 0 0 2 2 2 1 Cellulose binding domain Esterase PF00756.20 KIR66196.1 - 0.006 16.3 0.1 0.041 13.5 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KIR66196.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PRIMA1 PF16101.5 KIR66196.1 - 0.83 9.7 3.8 1.6 8.8 3.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FCD PF07729.12 KIR66197.1 - 8.8e-27 94.0 10.6 1.6e-26 93.1 10.6 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KIR66197.1 - 7.8e-18 63.9 0.1 1.7e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 KIR66197.1 - 0.0014 18.6 0.1 0.0067 16.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HSCB_C PF07743.13 KIR66197.1 - 0.0037 17.7 0.5 0.0089 16.5 0.5 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain MarR_2 PF12802.7 KIR66197.1 - 0.0056 16.6 1.3 0.021 14.7 0.1 2.6 3 0 0 3 3 3 1 MarR family HTH_41 PF14502.6 KIR66197.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR66197.1 - 0.016 14.8 0.8 0.095 12.3 0.1 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FadR_C PF07840.12 KIR66197.1 - 0.024 14.5 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 FadR C-terminal domain Rrf2 PF02082.20 KIR66197.1 - 0.026 14.9 0.2 0.95 9.9 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator HTH_CodY PF08222.11 KIR66197.1 - 0.032 13.8 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_11 PF08279.12 KIR66197.1 - 0.12 12.4 0.4 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 HTH domain HTH_17 PF12728.7 KIR66197.1 - 0.13 12.4 0.2 28 5.0 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain Glyco_hydro_59 PF02057.15 KIR66198.1 - 3.4e-113 377.7 0.8 4.5e-113 377.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Ricin_B_lectin PF00652.22 KIR66198.1 - 5.6e-27 94.5 11.1 1.5e-26 93.1 11.1 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66198.1 - 1.5e-26 93.0 20.8 3.7e-13 50.0 1.4 5.9 3 2 3 6 6 6 3 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_59M PF17387.2 KIR66198.1 - 1.7e-08 34.6 0.1 3.6e-06 27.1 0.1 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 central domain Laminin_G_3 PF13385.6 KIR66198.1 - 8.5e-06 26.0 5.2 8.5e-06 26.0 5.2 4.4 3 2 3 6 6 6 1 Concanavalin A-like lectin/glucanases superfamily SBP_bac_8 PF13416.6 KIR66199.1 - 1.3e-27 97.3 0.6 1.8e-27 96.9 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR66199.1 - 8.4e-24 85.1 3.6 1.6e-23 84.2 3.6 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR66200.1 - 1.8e-11 44.1 13.4 1.8e-11 44.1 13.4 2.1 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component MR_MLE_C PF13378.6 KIR66201.1 - 4.2e-42 144.2 1.5 4.2e-42 144.2 1.5 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR66201.1 - 8.9e-10 38.8 0.5 2.7e-09 37.2 0.5 1.8 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ricin_B_lectin PF00652.22 KIR66202.1 - 6.9e-28 97.4 13.1 6.9e-28 97.4 13.1 2.2 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66202.1 - 9.3e-26 90.4 23.5 4.9e-14 52.8 6.2 5.1 3 1 2 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Chloroplast_duf PF14476.6 KIR66202.1 - 0.55 9.2 2.9 1 8.3 2.9 1.3 1 0 0 1 1 1 0 Petal formation-expressed ET PF01684.16 KIR66202.1 - 1.3 9.4 6.2 9 6.7 0.2 3.5 1 1 2 3 3 3 0 ET module TetR_N PF00440.23 KIR66203.1 - 2.1e-11 43.4 0.1 7e-11 41.7 0.1 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 KIR66203.1 - 9.3e-10 39.2 3.6 9.3e-10 39.2 3.6 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 KIR66203.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_10 PF16295.5 KIR66203.1 - 0.2 11.9 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 KIR66204.1 - 7.5e-26 90.8 0.0 7.8e-25 87.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR66204.1 - 8.4e-16 58.2 0.1 4.4e-15 55.9 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIR66204.1 - 6.5e-06 25.8 0.0 7.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIR66204.1 - 3.2e-05 23.9 0.3 5.3e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIR66204.1 - 0.0013 18.7 4.0 0.0023 17.9 4.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding AdoHcyase_NAD PF00670.21 KIR66204.1 - 0.0033 17.5 0.3 0.006 16.7 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NmrA PF05368.13 KIR66204.1 - 0.012 15.1 1.1 0.018 14.6 1.1 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_zinc_N PF00107.26 KIR66204.1 - 0.027 14.5 0.2 0.1 12.6 0.3 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FAD_oxidored PF12831.7 KIR66204.1 - 0.24 10.7 3.0 0.31 10.3 3.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Peripla_BP_3 PF13377.6 KIR66205.1 - 1.5e-25 90.4 1.6 2.9e-25 89.5 1.6 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR66205.1 - 4.5e-19 68.0 0.2 8.4e-19 67.1 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 KIR66205.1 - 1.5e-15 57.4 0.0 1.9e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR66205.1 - 5.5e-05 22.9 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 KIR66205.1 - 0.00093 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR66205.1 - 0.0013 19.1 0.2 0.0048 17.2 0.2 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KIR66205.1 - 0.0022 17.7 0.1 0.0084 15.9 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR66205.1 - 0.0041 17.0 0.1 0.04 13.8 0.0 2.8 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 KIR66205.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.23 KIR66205.1 - 0.034 13.9 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 MerR family regulatory protein HTH_23 PF13384.6 KIR66205.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain YdaS_antitoxin PF15943.5 KIR66205.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_24 PF13412.6 KIR66205.1 - 0.083 12.5 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TetR_N PF00440.23 KIR66205.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 KIR66205.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_5 PF01022.20 KIR66205.1 - 0.1 12.5 1.0 0.34 10.8 0.0 2.4 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 KIR66205.1 - 0.11 12.6 0.5 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 KIR66205.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 MarR family Trehalase PF01204.18 KIR66206.1 - 8.6e-07 28.1 0.0 1.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase RicinB_lectin_2 PF14200.6 KIR66207.1 - 8.8e-26 90.5 19.3 7.5e-17 61.8 4.2 3.5 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66207.1 - 1e-15 58.1 13.9 2.5e-15 56.9 11.2 2.5 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_39 PF01229.17 KIR66207.1 - 0.00075 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 DUF4987 PF16377.5 KIR66207.1 - 0.083 13.1 0.4 0.24 11.6 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF1859 PF08948.10 KIR66207.1 - 0.18 11.8 3.1 0.13 12.2 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1859) DPBB_1 PF03330.18 KIR66207.1 - 0.47 10.8 2.7 10 6.5 0.1 3.0 2 1 1 3 3 3 0 Lytic transglycolase GerE PF00196.19 KIR66208.1 - 5.1e-15 54.8 0.0 8.3e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_12 PF13424.6 KIR66208.1 - 1.8e-06 28.1 18.3 0.0011 19.3 0.7 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat MctB PF11382.8 KIR66208.1 - 0.0045 16.8 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB TPR_4 PF07721.14 KIR66208.1 - 0.0059 17.1 0.5 0.0059 17.1 0.5 8.2 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIR66208.1 - 0.021 14.9 9.3 0.081 13.1 0.8 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_23 PF13384.6 KIR66208.1 - 0.032 14.0 0.7 0.095 12.5 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR66208.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR66208.1 - 0.11 12.4 1.1 0.56 10.1 0.0 2.7 3 0 0 3 3 3 0 ECF sigma factor TPR_MalT PF17874.1 KIR66208.1 - 0.11 11.8 16.5 0.01 15.3 8.0 2.8 2 1 1 3 3 3 0 MalT-like TPR region TPR_7 PF13176.6 KIR66208.1 - 0.46 10.6 2.4 13 6.1 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIR66208.1 - 1.4 8.9 9.4 1.6 8.7 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RimK PF08443.11 KIR66209.1 - 0.00043 19.9 0.0 0.00078 19.1 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain SurA_N_3 PF13624.6 KIR66210.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Haem_degrading PF03928.14 KIR66210.1 - 0.11 12.6 1.8 0.2 11.7 1.8 1.4 1 0 0 1 1 1 0 Haem-degrading DUF4132 PF13569.6 KIR66211.1 - 7.6e-26 91.0 0.0 1.3e-25 90.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4132) SWIM PF04434.17 KIR66212.1 - 4.8e-05 22.9 1.9 4.8e-05 22.9 1.9 1.8 2 0 0 2 2 2 1 SWIM zinc finger adh_short_C2 PF13561.6 KIR66213.1 - 1.3e-55 188.5 9.7 1.6e-55 188.2 9.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66213.1 - 5.6e-46 156.5 5.0 6.6e-46 156.2 5.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66213.1 - 3.7e-20 72.6 2.5 5.1e-20 72.1 2.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR66213.1 - 0.00025 20.6 2.9 0.00068 19.2 2.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 KIR66213.1 - 0.018 16.0 6.6 0.025 15.6 4.4 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator TetR_C_24 PF17932.1 KIR66214.1 - 1.1e-28 99.8 0.0 1.9e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR66214.1 - 3.5e-19 68.3 1.3 6.5e-19 67.5 0.2 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 KIR66214.1 - 0.00064 19.8 0.0 0.0015 18.6 0.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 KIR66214.1 - 0.0011 19.3 1.1 0.019 15.3 0.1 2.5 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 KIR66214.1 - 0.033 14.2 0.0 0.09 12.8 0.0 1.8 1 1 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain HTH_20 PF12840.7 KIR66214.1 - 0.084 12.9 0.0 8.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 KIR66214.1 - 0.12 12.8 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Acyl-CoA_dh_1 PF00441.24 KIR66215.1 - 1.9e-48 164.5 8.5 3.1e-48 163.8 8.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR66215.1 - 2.8e-29 101.2 0.0 5.2e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIR66215.1 - 3e-29 102.0 0.2 6.3e-29 100.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIR66215.1 - 5.5e-25 88.2 6.6 5.5e-25 88.2 6.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SnoaL_2 PF12680.7 KIR66216.1 - 2.5e-12 47.3 10.2 1.4e-06 28.9 4.4 3.9 2 2 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 KIR66216.1 - 3.3e-06 27.4 1.9 0.044 14.2 1.5 3.4 2 2 0 3 3 3 2 Domain of unknown function (DUF4440) WI12 PF07107.11 KIR66216.1 - 3.3e-05 23.9 0.2 0.0057 16.8 0.0 2.2 2 0 0 2 2 2 2 Wound-induced protein WI12 ADH_zinc_N PF00107.26 KIR66217.1 - 5.9e-23 81.3 1.8 1.2e-22 80.3 1.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR66217.1 - 3.7e-10 41.0 0.5 3.7e-10 41.0 0.5 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIR66217.1 - 0.016 14.7 1.5 0.016 14.7 1.5 1.6 2 0 0 2 2 2 0 short chain dehydrogenase ADH_N PF08240.12 KIR66217.1 - 0.12 12.2 1.9 0.73 9.7 0.1 2.8 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIR66217.1 - 8.6 5.6 13.6 3.8 6.8 7.5 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MaoC_dehydratas PF01575.19 KIR66218.1 - 5.3e-25 87.4 0.0 6.8e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIR66218.1 - 0.02 15.0 0.0 0.024 14.8 0.0 1.3 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase Flavin_Reduct PF01613.18 KIR66219.1 - 1.2e-29 103.3 0.2 1.4e-29 103.2 0.2 1.0 1 0 0 1 1 1 1 Flavin reductase like domain SBP_bac_5 PF00496.22 KIR66220.1 - 1.8e-53 181.9 9.6 2.6e-53 181.4 9.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KIR66221.1 - 1.3e-44 152.2 11.6 1.3e-44 152.2 11.6 1.8 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KIR66222.1 - 7.6e-27 94.5 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR66222.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR66222.1 - 2.9e-05 24.5 0.6 5.2e-05 23.7 0.6 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR66222.1 - 0.00013 22.2 0.3 0.00097 19.4 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR66222.1 - 0.00031 20.9 0.1 0.0014 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIR66222.1 - 0.00039 20.3 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system PhoH PF02562.16 KIR66222.1 - 0.00068 19.1 0.3 0.16 11.4 0.2 2.4 2 1 0 2 2 2 1 PhoH-like protein oligo_HPY PF08352.12 KIR66222.1 - 0.0037 17.7 0.0 0.0071 16.8 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region NACHT PF05729.12 KIR66222.1 - 0.0091 15.9 0.1 0.053 13.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 KIR66222.1 - 0.013 14.9 0.0 0.48 9.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KIR66222.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KIR66222.1 - 0.02 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 KIR66222.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 KIR66222.1 - 0.025 14.3 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 KIR66222.1 - 0.068 13.7 0.0 0.079 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR66222.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KIR66222.1 - 0.095 12.7 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KIR66222.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.29 KIR66222.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIR66222.1 - 0.16 11.9 1.2 0.22 11.4 0.2 1.7 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 KIR66222.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Tugs PF17840.1 KIR66222.1 - 0.49 10.6 4.7 1.2 9.4 0.1 3.2 2 1 1 3 3 3 0 Tethering Ubl4a to BAGS domain Thiolase_N PF00108.23 KIR66223.1 - 1.2e-17 64.2 2.4 4.9e-16 58.9 2.4 2.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIR66223.1 - 1.1e-08 34.7 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIR66223.1 - 0.023 14.3 0.2 0.023 14.3 0.2 3.0 4 1 1 5 5 5 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIR66223.1 - 0.061 13.2 1.0 10 6.1 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 KIR66224.1 - 3.8e-41 140.7 2.5 5.5e-41 140.2 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR66224.1 - 1.1e-33 116.8 6.7 9.1e-33 113.7 6.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR66224.1 - 2e-19 70.2 2.8 2.9e-19 69.7 2.8 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KIR66224.1 - 0.15 11.4 2.1 0.61 9.4 2.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyoxalase PF00903.25 KIR66225.1 - 2.8e-11 43.7 0.0 4.6e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIR66225.1 - 2.8e-05 24.4 0.0 5.5e-05 23.4 0.0 1.6 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR66225.1 - 8.4e-05 23.3 0.0 0.00017 22.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KIR66225.1 - 0.022 14.9 0.1 0.031 14.4 0.1 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Lactamase_B PF00753.27 KIR66226.1 - 1.3e-17 64.5 10.4 3.1e-17 63.2 10.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIR66226.1 - 7e-09 35.5 1.4 1.3e-07 31.4 1.4 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KIR66226.1 - 0.0059 16.1 0.0 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain DUF3562 PF12085.8 KIR66226.1 - 0.02 14.5 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) AMP-binding PF00501.28 KIR66227.1 - 1e-71 241.8 0.5 1.2e-71 241.5 0.5 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR66227.1 - 3.3e-16 60.0 2.4 5.2e-16 59.4 0.8 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_N PF02771.16 KIR66228.1 - 1.4e-22 80.5 0.1 3.9e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIR66228.1 - 1.6e-18 67.3 3.9 3.3e-18 66.3 3.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIR66228.1 - 4e-18 65.4 0.0 7e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KIR66228.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Bac_luciferase PF00296.20 KIR66229.1 - 1.4e-55 188.9 0.0 1.9e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ECH_1 PF00378.20 KIR66230.1 - 1e-26 93.8 0.1 2.3e-25 89.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIR66230.1 - 1.7e-08 34.4 0.0 3.9e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Bac_luciferase PF00296.20 KIR66231.1 - 2.4e-56 191.5 0.7 4e-56 190.8 0.7 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Glyoxalase_6 PF18029.1 KIR66232.1 - 1.2e-08 35.7 0.3 1.4e-08 35.5 0.3 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KIR66232.1 - 2.4e-06 27.8 0.0 5.5e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Neuralized PF07177.12 KIR66232.1 - 0.065 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Neuralized F420_oxidored PF03807.17 KIR66233.1 - 1.5e-20 73.6 0.2 3.1e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KIR66233.1 - 1.3e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KIR66233.1 - 0.00019 21.7 0.1 0.00043 20.5 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 KIR66233.1 - 0.0011 18.1 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 3HCDH_N PF02737.18 KIR66233.1 - 0.0024 17.8 0.5 0.0039 17.1 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIR66233.1 - 0.0024 17.2 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIR66233.1 - 0.01 15.8 0.1 0.18 11.8 0.1 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 KIR66233.1 - 0.017 14.6 0.8 0.03 13.8 0.8 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 KIR66233.1 - 0.031 14.7 2.2 0.051 14.0 0.8 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KIR66233.1 - 0.059 12.9 0.3 0.099 12.2 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.16 KIR66233.1 - 0.15 11.7 2.2 0.31 10.7 0.7 2.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ABC_tran PF00005.27 KIR66234.1 - 2.4e-27 96.1 0.0 3.1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66234.1 - 1.8e-07 31.3 0.4 0.0092 15.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR66234.1 - 0.0029 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KIR66234.1 - 0.0047 16.5 0.1 0.51 9.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIR66234.1 - 0.035 13.5 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR66234.1 - 0.04 14.4 0.0 0.064 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIR66234.1 - 0.052 13.5 0.1 0.51 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KIR66234.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase B12-binding PF02310.19 KIR66235.1 - 1.1e-12 48.1 0.9 8.2e-12 45.2 0.2 2.4 2 0 0 2 2 2 1 B12 binding domain Radical_SAM PF04055.21 KIR66235.1 - 2.7e-12 47.4 0.0 6.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily p450 PF00067.22 KIR66237.1 - 1.5e-29 103.1 0.0 2.9e-24 85.6 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 DUF5076 PF16826.5 KIR66237.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) MFS_1 PF07690.16 KIR66238.1 - 3.4e-26 92.0 49.7 3.4e-26 92.0 49.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KIR66238.1 - 2.2e-19 69.3 40.5 2.7e-19 69.0 40.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector Cellulase PF00150.18 KIR66239.1 - 6e-44 150.6 0.0 8.1e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_2 PF00553.19 KIR66239.1 - 3.6e-28 97.9 9.7 3.9e-28 97.7 7.3 2.2 2 0 0 2 2 2 1 Cellulose binding domain CBM49 PF09478.10 KIR66239.1 - 0.00032 21.0 0.1 0.00067 19.9 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PapD_C PF02753.17 KIR66239.1 - 0.021 15.2 0.0 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain OCD_Mu_crystall PF02423.15 KIR66240.1 - 1.4e-52 178.6 0.0 1.9e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Pro_Al_protease PF02983.14 KIR66244.1 - 4.3e-13 49.1 5.2 4.3e-13 49.1 5.2 4.3 4 1 0 5 5 5 1 Alpha-lytic protease prodomain Trypsin PF00089.26 KIR66244.1 - 2.5e-08 34.0 3.4 3.6e-08 33.5 2.3 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 KIR66244.1 - 0.0058 17.5 4.2 0.027 15.4 0.5 3.1 2 2 0 2 2 2 1 Trypsin-like peptidase domain Pico_P2A PF00947.19 KIR66244.1 - 3.6 7.6 5.6 0.93 9.5 1.7 1.9 2 1 0 2 2 2 0 Picornavirus core protein 2A HxlR PF01638.17 KIR66246.1 - 1.2e-24 86.0 0.0 1.5e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 KIR66246.1 - 1e-05 25.3 0.1 1.9e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KIR66246.1 - 1.1e-05 25.4 0.3 2e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KIR66246.1 - 0.0053 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KIR66246.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Polysacc_deac_1 PF01522.21 KIR66247.1 - 4e-31 107.5 0.0 4.6e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_43 PF04616.14 KIR66248.1 - 2e-97 326.0 0.1 2.5e-97 325.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIR66248.1 - 4.2e-44 150.7 0.0 6.7e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SBP_bac_1 PF01547.25 KIR66249.1 - 8.4e-39 134.4 12.9 8.4e-39 134.4 12.9 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR66249.1 - 8.8e-38 130.7 7.0 1.3e-37 130.1 7.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR66249.1 - 2.7e-06 27.0 0.2 9.9e-05 21.9 0.1 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein DUF3663 PF12404.8 KIR66249.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Peptidase BPD_transp_1 PF00528.22 KIR66250.1 - 1.5e-14 54.1 14.6 1.5e-14 54.1 14.6 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR66251.1 - 1.8e-18 67.0 16.4 1.8e-18 67.0 16.4 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3566 PF12089.8 KIR66251.1 - 0.22 11.9 3.7 0.48 10.8 0.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) Peripla_BP_3 PF13377.6 KIR66252.1 - 3.1e-44 151.2 0.1 3.5e-42 144.6 0.1 2.3 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66252.1 - 1.7e-26 93.3 0.0 2.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR66252.1 - 5.3e-14 51.7 1.5 5.4e-14 51.7 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR66252.1 - 5.2e-12 45.9 0.0 7.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR66252.1 - 0.00014 22.1 0.5 0.00054 20.3 0.5 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66252.1 - 0.00067 19.7 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix DUF3853 PF12964.7 KIR66252.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) HTH_29 PF13551.6 KIR66252.1 - 0.072 13.1 1.0 0.35 10.9 1.0 2.2 1 1 0 1 1 1 0 Winged helix-turn helix ATP-synt_F PF01990.17 KIR66252.1 - 0.15 12.4 0.0 0.49 10.8 0.0 1.7 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit TetR_N PF00440.23 KIR66252.1 - 0.17 11.7 0.4 0.74 9.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family CBM_2 PF00553.19 KIR66253.1 - 7.8e-29 100.0 10.5 2.6e-28 98.3 10.5 1.9 1 0 0 1 1 1 1 Cellulose binding domain Esterase_phd PF10503.9 KIR66253.1 - 7.6e-05 22.3 0.4 0.00015 21.3 0.4 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR66253.1 - 0.0018 17.8 0.2 0.0032 17.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIR66253.1 - 0.063 12.9 0.2 0.36 10.4 0.2 1.9 1 1 0 1 1 1 0 Putative esterase DLH PF01738.18 KIR66253.1 - 0.42 10.1 1.7 0.81 9.2 0.6 1.8 1 1 1 2 2 2 0 Dienelactone hydrolase family Trypsin PF00089.26 KIR66254.1 - 4.5e-05 23.4 1.9 0.0031 17.3 0.9 2.2 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 KIR66254.1 - 0.039 14.9 2.0 0.061 14.2 0.1 2.3 3 0 0 3 3 3 0 Trypsin-like peptidase domain BTAD PF03704.17 KIR66255.1 - 2.4e-29 102.6 7.3 3.9e-29 102.0 7.3 1.3 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Trans_reg_C PF00486.28 KIR66255.1 - 4.4e-08 33.1 0.0 8.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TPR_14 PF13428.6 KIR66255.1 - 0.014 16.2 15.0 0.37 11.7 0.2 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIR66255.1 - 0.017 15.7 17.5 1.4 9.7 3.9 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIR66255.1 - 0.017 15.2 2.3 0.35 11.1 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIR66255.1 - 0.049 13.9 2.2 2.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIR66255.1 - 0.079 13.6 1.6 0.079 13.6 1.6 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIR66255.1 - 0.084 13.4 7.5 0.9 10.1 1.8 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat GerE PF00196.19 KIR66256.1 - 2.1e-16 59.2 0.0 3.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 KIR66256.1 - 5.5e-16 59.4 3.3 5.5e-16 59.4 3.3 4.6 3 2 0 3 3 3 1 AAA ATPase domain HTH_38 PF13936.6 KIR66256.1 - 1.8e-05 24.4 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIR66256.1 - 3.4e-05 23.4 0.0 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR66256.1 - 0.00019 21.1 0.0 0.00095 18.9 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain AAA_22 PF13401.6 KIR66256.1 - 0.002 18.4 0.0 0.0084 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR66256.1 - 0.0028 17.4 0.1 0.011 15.4 0.1 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KIR66256.1 - 0.014 15.3 0.1 0.04 13.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain HTH_24 PF13412.6 KIR66256.1 - 0.04 13.5 0.0 0.17 11.5 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TPR_8 PF13181.6 KIR66256.1 - 0.064 13.5 0.1 0.22 11.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat NTPase_1 PF03266.15 KIR66256.1 - 0.19 11.6 0.2 0.32 10.9 0.2 1.3 1 0 0 1 1 1 0 NTPase DAP3 PF10236.9 KIR66256.1 - 0.23 10.6 0.1 0.32 10.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TPR_10 PF13374.6 KIR66256.1 - 2.3 8.2 10.6 0.27 11.1 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Kelch_1 PF01344.25 KIR66257.1 - 1.1e-38 130.6 8.6 2.3e-07 30.3 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Peptidase_S8 PF00082.22 KIR66257.1 - 2.9e-36 125.3 9.8 2.9e-36 125.3 9.8 3.0 3 0 0 3 3 3 1 Subtilase family CarboxypepD_reg PF13620.6 KIR66257.1 - 1.5e-33 114.9 43.8 4.1e-16 59.0 4.8 6.6 6 0 0 6 6 6 4 Carboxypeptidase regulatory-like domain Kelch_6 PF13964.6 KIR66257.1 - 1.6e-29 101.2 2.8 5.4e-06 26.5 0.0 5.9 2 1 3 5 5 5 5 Kelch motif CarbopepD_reg_2 PF13715.6 KIR66257.1 - 2.7e-26 91.4 0.4 2.2e-09 37.2 0.0 4.7 4 0 0 4 4 4 4 CarboxypepD_reg-like domain Kelch_3 PF13415.6 KIR66257.1 - 5.6e-21 74.3 17.0 3.2e-05 24.1 0.0 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KIR66257.1 - 1.8e-18 65.7 0.5 0.0055 16.6 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 KIR66257.1 - 1.5e-14 53.7 10.0 0.0006 19.8 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain PEGA PF08308.11 KIR66257.1 - 6.9e-06 25.9 0.0 2.6 8.0 0.0 3.9 3 0 0 3 3 3 2 PEGA domain Kelch_5 PF13854.6 KIR66257.1 - 2.4e-05 24.2 12.7 0.53 10.3 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Cleaved_Adhesin PF07675.11 KIR66257.1 - 0.00034 20.6 0.4 0.00034 20.6 0.4 3.5 4 1 1 5 5 4 1 Cleaved Adhesin Domain DUF3823 PF12866.7 KIR66257.1 - 0.05 13.9 0.0 9.3 6.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3823) N-terminal domain BsuPI PF12690.7 KIR66257.1 - 0.057 13.5 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 Intracellular proteinase inhibitor DUF1573 PF07610.11 KIR66257.1 - 0.066 13.2 0.2 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) Invasin_D3 PF09134.10 KIR66257.1 - 1.7 9.0 27.2 1.1 9.6 0.0 5.9 5 1 0 6 6 6 0 Invasin, domain 3 Trans_reg_C PF00486.28 KIR66258.1 - 1.8e-13 50.3 0.1 3e-13 49.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Polyketide_cyc2 PF10604.9 KIR66259.1 - 5.6e-08 33.2 6.0 6.2e-08 33.0 6.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Adeno_PX PF05829.12 KIR66260.1 - 0.11 12.4 0.2 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) GerE PF00196.19 KIR66261.1 - 5.3e-14 51.5 0.0 8.3e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 KIR66261.1 - 4.5e-12 46.7 0.7 4.5e-12 46.7 0.7 4.2 5 1 0 5 5 5 1 AAA ATPase domain HTH_23 PF13384.6 KIR66261.1 - 0.00026 20.7 0.9 0.0017 18.1 0.1 2.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KIR66261.1 - 0.0016 18.1 7.4 0.046 13.4 0.1 4.3 4 0 0 4 4 4 2 Sigma-70, region 4 AAA_22 PF13401.6 KIR66261.1 - 0.065 13.5 0.0 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR66261.1 - 0.18 11.7 0.0 0.6 10.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Phage_holin_8 PF16931.5 KIR66262.1 - 3.3 7.7 10.5 0.11 12.5 0.5 2.5 2 0 0 2 2 2 0 Putative phage holin Catalase PF00199.19 KIR66263.1 - 8.9e-167 555.0 0.0 1.1e-166 554.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KIR66263.1 - 1e-30 106.4 0.0 1.7e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KIR66263.1 - 4.8e-23 81.1 0.0 9.8e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Ferric_reduct PF01794.19 KIR66264.1 - 0.021 14.9 1.9 0.021 14.9 1.9 2.8 2 1 0 2 2 2 0 Ferric reductase like transmembrane component AMP-binding PF00501.28 KIR66265.1 - 2.9e-76 256.8 0.0 3.6e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR66265.1 - 0.002 19.1 2.3 0.0039 18.1 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TauD PF02668.16 KIR66266.1 - 7.7e-23 81.6 0.0 1e-22 81.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_N PF08240.12 KIR66267.1 - 2.2e-23 82.2 0.1 4e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIR66267.1 - 1.1e-21 77.2 0.4 1.1e-21 77.2 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR66267.1 - 6.7e-09 36.9 0.0 1.4e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIR66267.1 - 1.2e-05 24.9 0.1 1.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PALP PF00291.25 KIR66267.1 - 0.0026 17.2 3.3 0.0046 16.4 3.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.21 KIR66267.1 - 0.0062 15.8 2.6 0.011 15.1 2.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.22 KIR66268.1 - 4.6e-157 523.2 0.1 5.2e-157 523.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KIR66268.1 - 9.1e-06 25.3 0.0 0.00011 21.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) ADH_zinc_N PF00107.26 KIR66269.1 - 2.1e-26 92.4 0.8 3.7e-26 91.6 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR66269.1 - 7.2e-26 90.2 0.1 1.4e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIR66269.1 - 8.9e-16 59.2 0.2 1.9e-15 58.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIR66269.1 - 0.11 11.8 1.8 0.21 10.8 1.8 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MBOAT_2 PF13813.6 KIR66269.1 - 0.12 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family SIS_2 PF13580.6 KIR66269.1 - 0.13 12.3 2.7 0.12 12.3 1.2 1.7 2 0 0 2 2 2 0 SIS domain HupF_HypC PF01455.18 KIR66269.1 - 0.19 11.9 5.9 1.1 9.4 0.5 3.4 4 0 0 4 4 4 0 HupF/HypC family TrkA_C PF02080.21 KIR66269.1 - 0.25 11.2 1.6 21 5.0 0.1 2.9 3 0 0 3 3 3 0 TrkA-C domain Bmp PF02608.14 KIR66270.1 - 1.2e-20 73.7 0.1 3.4e-20 72.2 0.1 1.6 1 1 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Peripla_BP_1 PF00532.21 KIR66270.1 - 0.00028 20.4 0.1 0.00048 19.6 0.1 1.4 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family ABC_tran PF00005.27 KIR66271.1 - 3.1e-46 157.3 0.0 3.4e-28 98.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR66271.1 - 1.6e-06 28.2 0.2 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR66271.1 - 0.0036 17.0 0.1 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain FliT PF05400.13 KIR66271.1 - 0.016 16.0 0.9 0.043 14.6 0.9 1.8 1 0 0 1 1 1 0 Flagellar protein FliT AAA_10 PF12846.7 KIR66271.1 - 0.02 13.8 0.1 2.7 6.8 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain RsgA_GTPase PF03193.16 KIR66271.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KIR66271.1 - 0.053 13.9 0.0 0.34 11.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KIR66271.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIR66271.1 - 0.19 12.0 0.2 5.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIR66271.1 - 0.24 11.9 0.1 0.39 11.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 KIR66272.1 - 2.4e-33 115.5 32.6 3.1e-33 115.1 32.6 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component PadR PF03551.14 KIR66274.1 - 1.2e-08 34.8 0.0 3.3e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family TPR_12 PF13424.6 KIR66275.1 - 2.2e-09 37.4 7.2 0.026 14.8 0.1 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KIR66275.1 - 0.0061 16.4 0.1 0.0061 16.4 0.1 5.1 7 0 0 7 7 7 1 Tetratricopeptide repeat HHH_5 PF14520.6 KIR66276.1 - 6.5e-07 29.9 0.0 7.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 KIR66276.1 - 2.7e-06 27.0 0.0 3.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH PF00633.23 KIR66276.1 - 0.013 15.4 0.0 0.042 13.7 0.0 2.0 1 1 1 2 2 2 0 Helix-hairpin-helix motif HD_3 PF13023.6 KIR66277.1 - 6.2e-24 84.8 0.1 7.7e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KIR66277.1 - 1.4e-09 38.0 0.5 3.4e-09 36.7 0.5 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KIR66277.1 - 0.0011 19.2 1.2 0.0034 17.6 1.2 1.9 1 1 0 1 1 1 1 HD domain HTH_31 PF13560.6 KIR66279.1 - 0.01 16.1 0.9 0.033 14.5 0.9 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KIR66279.1 - 0.16 12.1 0.1 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_31 PF13560.6 KIR66281.1 - 2.4e-09 37.4 1.5 2.4e-09 37.4 1.5 3.8 4 1 1 5 5 5 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66281.1 - 3.8e-05 23.6 0.0 8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR66281.1 - 0.0038 17.2 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_12 PF13424.6 KIR66281.1 - 1.7 9.0 16.6 2.2 8.6 0.6 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIR66281.1 - 9.1 6.3 7.7 7 6.7 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 KIR66283.1 - 2.1e-17 63.9 11.4 3.4e-17 63.2 11.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Melibiase_2 PF16499.5 KIR66284.1 - 2.5e-76 256.6 2.7 3.5e-76 256.1 2.7 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 KIR66284.1 - 3.6e-23 82.2 8.9 1.8e-22 79.9 8.8 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66284.1 - 2e-22 79.7 15.8 3.6e-11 43.6 3.5 3.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Melibiase_C PF17801.1 KIR66284.1 - 6.3e-17 61.4 0.2 1.6e-16 60.1 0.2 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIR66284.1 - 5.5e-10 38.7 0.0 9.7e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 KIR66284.1 - 0.018 12.8 0.1 0.037 11.8 0.1 1.4 2 0 0 2 2 2 0 Raffinose synthase or seed imbibition protein Sip1 Aldo_ket_red PF00248.21 KIR66285.1 - 2.3e-70 237.1 0.0 2.6e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_28 PF13521.6 KIR66285.1 - 0.033 14.4 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Glyoxalase PF00903.25 KIR66286.1 - 4.2e-08 33.4 0.0 7.9e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR66286.1 - 0.00018 22.2 0.0 0.00026 21.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KIR66286.1 - 0.022 15.0 0.0 1.9 8.8 0.0 2.1 1 1 1 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HTH_IclR PF09339.10 KIR66287.1 - 8.8e-11 41.4 3.0 3e-10 39.7 3.0 2.0 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 KIR66287.1 - 4.6e-10 39.4 0.1 7e-09 35.6 0.1 2.5 1 1 0 1 1 1 1 Bacterial transcriptional regulator HTH_11 PF08279.12 KIR66287.1 - 1.9e-05 24.5 0.2 3.6e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 KIR66287.1 - 0.0012 18.7 1.1 0.004 17.0 1.1 1.9 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR66287.1 - 0.005 16.4 0.6 0.01 15.4 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KIR66287.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 KIR66288.1 - 3.3e-12 46.0 0.7 8.4e-12 44.7 0.7 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 KIR66288.1 - 4.8e-10 39.4 0.5 3.1e-09 36.7 0.1 2.4 2 2 0 2 2 2 1 Bacterial transcriptional regulator HTH_24 PF13412.6 KIR66288.1 - 0.00025 20.6 0.3 0.00061 19.3 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KIR66288.1 - 0.0016 18.3 0.1 0.0043 17.0 0.1 1.7 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 KIR66288.1 - 0.0063 16.4 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 MarR family Cytochrom_D1 PF02239.16 KIR66288.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Fer4 PF00037.27 KIR66290.1 - 1.9e-08 33.8 19.3 4.7e-07 29.4 4.7 2.9 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KIR66290.1 - 4.1e-07 30.0 3.8 2.3e-05 24.4 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR66290.1 - 7.4e-05 23.3 14.8 0.0012 19.4 14.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR66290.1 - 8e-05 22.6 3.9 8e-05 22.6 3.9 2.4 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 KIR66290.1 - 0.00013 22.3 5.7 0.00087 19.7 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KIR66290.1 - 0.00017 21.6 15.6 0.0053 16.8 15.9 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR66290.1 - 0.00023 22.0 7.0 0.008 17.1 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KIR66290.1 - 0.00024 21.3 1.3 0.00024 21.3 1.3 2.6 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 KIR66290.1 - 0.00025 21.0 4.2 0.00025 21.0 4.2 2.6 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KIR66290.1 - 0.00072 19.7 11.4 0.0013 18.9 11.4 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 KIR66290.1 - 0.0061 17.4 10.7 0.041 14.7 1.5 1.8 1 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIR66290.1 - 0.04 14.5 8.3 0.19 12.3 1.8 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 KIR66290.1 - 0.045 14.3 3.3 0.045 14.3 3.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIR66290.1 - 0.95 10.6 17.4 0.94 10.6 6.2 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain Pyr_redox_2 PF07992.14 KIR66291.1 - 4.9e-33 114.6 0.3 5.8e-33 114.4 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR66291.1 - 1.7e-19 70.2 0.0 3.1e-16 59.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR66291.1 - 7e-14 52.2 0.3 1.1e-11 45.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR66291.1 - 7.8e-09 34.7 0.2 2.4e-05 23.2 0.1 3.8 5 0 0 5 5 5 1 HI0933-like protein FAD_binding_2 PF00890.24 KIR66291.1 - 2.2e-08 33.6 3.5 0.00014 21.0 0.1 3.9 3 1 1 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 KIR66291.1 - 6.7e-08 32.7 0.1 3e-06 27.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIR66291.1 - 1.1e-06 28.0 0.2 8.8e-05 21.9 0.2 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KIR66291.1 - 4.9e-06 25.9 0.1 5.6e-05 22.5 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KIR66291.1 - 7.7e-06 25.5 2.2 0.0012 18.3 0.4 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase DAO PF01266.24 KIR66291.1 - 8.3e-06 25.6 8.9 0.035 13.7 0.4 3.9 2 2 2 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR66291.1 - 0.0017 18.4 7.6 0.23 11.5 0.1 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding GIDA PF01134.22 KIR66291.1 - 0.0032 16.6 3.5 0.42 9.6 0.3 3.6 3 1 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIR66291.1 - 0.0032 16.8 2.0 0.019 14.3 0.1 2.5 2 1 1 3 3 3 1 FAD binding domain XdhC_C PF13478.6 KIR66291.1 - 0.12 12.8 0.3 11 6.5 0.1 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 KIR66291.1 - 0.12 11.3 3.5 1.4 7.9 0.1 3.2 2 2 2 4 4 4 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KIR66291.1 - 0.16 12.4 0.3 0.45 11.0 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Cupin_2 PF07883.11 KIR66292.1 - 4.9e-09 35.8 0.1 7e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIR66292.1 - 3.3e-06 27.0 0.1 4e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIR66292.1 - 0.013 15.2 0.0 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) PCO_ADO PF07847.12 KIR66292.1 - 0.027 13.9 1.2 0.79 9.1 0.1 2.1 1 1 1 2 2 2 0 PCO_ADO Cupin_6 PF12852.7 KIR66292.1 - 0.041 13.6 0.1 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 Cupin ARD PF03079.14 KIR66292.1 - 0.09 13.0 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 ARD/ARD' family FmdA_AmdA PF03069.15 KIR66293.1 - 2e-28 99.3 0.0 7.7e-18 64.5 0.0 3.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family Ring_hydroxyl_B PF00866.18 KIR66294.1 - 8.5e-23 81.0 0.5 1.1e-22 80.7 0.5 1.1 1 0 0 1 1 1 1 Ring hydroxylating beta subunit SnoaL_4 PF13577.6 KIR66294.1 - 3.4e-07 30.4 2.5 4.6e-07 30.0 2.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Dabb PF07876.12 KIR66295.1 - 8.6e-17 61.6 0.0 9.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Glyoxalase PF00903.25 KIR66296.1 - 2.6e-16 60.0 3.2 8e-08 32.5 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CDC37_M PF08565.11 KIR66296.1 - 0.079 12.9 0.2 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain DUF2071 PF09844.9 KIR66297.1 - 1.8e-70 236.9 0.1 2e-70 236.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (COG2071) Abhydrolase_6 PF12697.7 KIR66298.1 - 0.00018 22.2 7.4 0.00018 22.2 7.4 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KIR66298.1 - 0.00027 21.1 0.1 0.00045 20.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KIR66298.1 - 0.0051 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KIR66298.1 - 0.028 14.3 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase DLH PF01738.18 KIR66298.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 KIR66298.1 - 0.23 11.3 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CHAT PF12770.7 KIR66299.1 - 1.2e-13 51.2 0.0 2.1e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 KIR66299.1 - 0.0075 15.5 0.2 0.012 14.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family C25 CHAT PF12770.7 KIR66300.1 - 4.7e-49 167.3 2.7 7.6e-49 166.7 2.7 1.3 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 KIR66301.1 - 4.7e-08 33.1 0.0 7.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIR66301.1 - 0.045 14.1 1.9 0.72 10.2 1.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Fer4_12 PF13353.6 KIR66302.1 - 2.4e-22 79.7 0.0 2.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIR66302.1 - 8.4e-08 32.4 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 KIR66302.1 - 2e-06 28.3 0.0 2.7e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Radical SAM superfamily AAA_2 PF07724.14 KIR66303.1 - 8.4e-32 110.6 0.0 1.2e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 KIR66303.1 - 6.9e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIR66303.1 - 1.2e-08 35.1 0.0 4.9e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIR66303.1 - 5.6e-06 26.8 0.0 1.6e-05 25.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIR66303.1 - 5.6e-05 22.9 0.1 0.00016 21.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KIR66303.1 - 0.0033 17.7 0.1 0.068 13.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIR66303.1 - 0.012 16.2 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR66303.1 - 0.022 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR66303.1 - 0.024 15.0 1.5 0.074 13.4 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 KIR66303.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR66303.1 - 0.071 12.5 0.1 0.32 10.3 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI CoiA PF06054.11 KIR66303.1 - 0.072 12.2 0.1 0.098 11.8 0.1 1.1 1 0 0 1 1 1 0 Competence protein CoiA-like family AAA_23 PF13476.6 KIR66303.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIR66303.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KIR66303.1 - 0.17 11.9 0.1 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KIR66303.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KIR66303.1 - 0.21 12.0 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KIR66303.1 - 0.23 11.4 0.3 3 7.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 KIR66305.1 - 3.1e-31 108.7 0.0 4.5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIR66305.1 - 2.2e-16 59.9 0.0 3.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2303 PF10065.9 KIR66305.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) GtrA PF04138.14 KIR66305.1 - 0.81 9.9 6.7 3.9 7.7 2.5 2.3 2 0 0 2 2 2 0 GtrA-like protein ABC_tran_CTD PF16326.5 KIR66306.1 - 0.025 14.8 0.9 0.21 11.9 0.1 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain HATPase_c_2 PF13581.6 KIR66307.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR66307.1 - 0.00012 22.6 0.0 0.00044 20.7 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rop-like PF05082.13 KIR66307.1 - 0.041 13.7 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Rop-like ACC_central PF08326.12 KIR66307.1 - 0.17 10.0 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region COX14 PF14880.6 KIR66307.1 - 0.6 10.0 3.3 5.2 7.0 0.2 2.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3775 PF12616.8 KIR66308.1 - 0.13 12.3 1.0 0.51 10.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) SrfB PF07520.11 KIR66309.1 - 0.00012 20.1 0.0 0.0002 19.4 0.0 1.2 1 0 0 1 1 1 1 Virulence factor SrfB MutL PF13941.6 KIR66309.1 - 0.057 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 MutL protein MreB_Mbl PF06723.13 KIR66309.1 - 0.064 12.1 0.9 0.087 11.6 0.2 1.5 2 0 0 2 2 2 0 MreB/Mbl protein StbA PF06406.11 KIR66309.1 - 0.22 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 StbA protein VWA_2 PF13519.6 KIR66311.1 - 2.5e-11 44.2 0.0 4.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIR66311.1 - 2e-07 31.4 0.0 2.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIR66311.1 - 2.6e-06 27.0 0.0 6.9e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 KIR66311.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Tubulin_2 PF13809.6 KIR66312.1 - 1.8e-39 135.9 0.0 2.6e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Tubulin PF00091.25 KIR66312.1 - 0.15 12.3 0.1 0.32 11.2 0.0 1.5 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain CBM_2 PF00553.19 KIR66313.1 - 1.5e-29 102.2 11.2 1.5e-29 102.2 11.2 2.8 3 1 0 3 3 3 1 Cellulose binding domain Pec_lyase_C PF00544.19 KIR66313.1 - 1.3e-18 67.4 10.8 1.3e-17 64.1 10.8 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIR66313.1 - 0.00055 19.8 10.5 0.00055 19.8 10.5 2.9 2 1 1 3 3 3 2 Right handed beta helix region NAD_binding_8 PF13450.6 KIR66314.1 - 1.6e-10 41.1 0.1 2.4e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KIR66314.1 - 2e-09 36.5 0.0 4.7e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIR66314.1 - 1.2e-08 34.5 1.9 1.9e-06 27.3 0.5 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR66314.1 - 5.2e-07 29.6 11.9 1.7e-05 24.6 0.4 3.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KIR66314.1 - 5.5e-07 29.1 0.0 3.1e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KIR66314.1 - 1.3e-06 27.9 0.1 0.0012 18.0 0.0 2.9 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KIR66314.1 - 3.7e-06 26.4 0.0 2.4e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR66314.1 - 4e-06 27.3 0.4 0.0061 17.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR66314.1 - 0.00017 21.1 0.4 0.00029 20.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIR66314.1 - 0.00018 21.5 3.0 0.77 9.7 0.1 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIR66314.1 - 0.0028 16.8 1.6 0.0074 15.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KIR66314.1 - 0.0048 16.2 0.4 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KIR66314.1 - 0.0076 15.4 1.0 0.73 8.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KIR66314.1 - 0.016 14.2 3.0 0.052 12.6 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KIR66314.1 - 0.067 13.3 0.7 0.45 10.6 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lipase_GDSL_2 PF13472.6 KIR66314.1 - 0.088 13.2 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HI0933_like PF03486.14 KIR66314.1 - 0.24 10.0 0.5 0.74 8.4 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KIR66314.1 - 0.32 10.2 3.9 0.87 8.8 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KIR66314.1 - 1.8 9.0 3.5 0.6 10.6 0.2 1.9 3 0 0 3 3 1 0 Putative NAD(P)-binding TetR_C_33 PF13305.6 KIR66315.1 - 1.5e-15 57.8 4.8 1.5e-15 57.8 4.8 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR66315.1 - 5.1e-09 35.8 0.8 1.5e-08 34.3 0.1 2.2 2 1 1 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 KIR66315.1 - 0.00013 22.7 0.8 0.0003 21.5 0.8 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 KIR66315.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family ACP_syn_III_C PF08541.10 KIR66316.1 - 6.3e-28 96.8 0.2 6.3e-28 96.8 0.2 2.3 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KIR66316.1 - 2.7e-18 65.6 1.3 2.7e-18 65.6 1.3 2.5 4 0 0 4 4 4 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KIR66316.1 - 1.5e-09 37.6 1.5 1.5e-09 37.6 1.5 1.5 1 1 1 2 2 2 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 KIR66316.1 - 0.0081 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain DUF357 PF04010.13 KIR66316.1 - 0.18 11.9 0.6 0.43 10.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) AAA_16 PF13191.6 KIR66317.1 - 1.1e-24 87.7 1.0 1.1e-24 87.7 1.0 4.0 3 1 1 4 4 3 1 AAA ATPase domain GerE PF00196.19 KIR66317.1 - 3.4e-18 64.9 0.1 8.5e-17 60.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 KIR66317.1 - 9.2e-05 22.7 0.0 0.00052 20.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Sigma70_r4_2 PF08281.12 KIR66317.1 - 0.00016 21.3 3.7 0.06 13.0 0.1 3.2 3 0 0 3 3 2 2 Sigma-70, region 4 DUF2791 PF10923.8 KIR66317.1 - 0.0031 16.4 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) HTH_38 PF13936.6 KIR66317.1 - 0.0067 16.2 0.1 0.023 14.4 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain TPR_19 PF14559.6 KIR66317.1 - 0.0097 16.4 2.9 0.0097 16.4 2.9 5.9 3 3 2 5 5 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIR66317.1 - 0.018 15.6 13.2 0.018 15.6 13.2 8.5 4 3 6 11 11 8 0 Tetratricopeptide repeat AAA PF00004.29 KIR66317.1 - 0.024 15.1 0.0 0.078 13.4 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KIR66317.1 - 0.025 14.3 0.2 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 KIR66317.1 - 0.029 14.3 0.2 0.34 10.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KIR66317.1 - 0.042 13.8 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KIR66317.1 - 0.049 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HTH_23 PF13384.6 KIR66317.1 - 0.15 11.9 3.8 0.34 10.8 0.4 3.5 2 1 1 3 3 3 0 Homeodomain-like domain HTH_40 PF14493.6 KIR66317.1 - 0.16 12.5 0.1 0.44 11.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_1 PF00515.28 KIR66317.1 - 1 9.3 4.0 40 4.3 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PP-binding PF00550.25 KIR66318.1 - 1.7e-11 44.3 0.1 2.1e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III_C PF08541.10 KIR66319.1 - 5e-06 26.6 0.0 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 KIR66319.1 - 1.8e-05 24.2 2.1 1.9e-05 24.1 0.9 1.7 1 1 1 2 2 2 1 Thiolase, N-terminal domain SpoVAD PF07451.11 KIR66319.1 - 0.0015 17.3 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.10 KIR66319.1 - 0.0086 15.9 1.0 0.33 10.8 1.2 2.9 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III L6_membrane PF05805.12 KIR66319.1 - 0.061 12.9 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 L6 membrane protein FAD_binding_3 PF01494.19 KIR66320.1 - 6.6e-79 265.7 0.8 8.3e-79 265.4 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR66320.1 - 1e-08 34.8 0.4 0.00032 20.0 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIR66320.1 - 1.1e-07 31.8 19.0 1.1e-06 28.5 0.9 3.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR66320.1 - 2.1e-07 31.4 0.0 0.00045 20.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR66320.1 - 6.9e-06 26.2 0.4 2.8e-05 24.3 0.4 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIR66320.1 - 0.0017 17.6 0.3 0.0027 17.0 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KIR66320.1 - 0.0041 17.6 1.5 0.021 15.3 0.1 2.6 2 0 0 2 2 2 1 XdhC Rossmann domain Thi4 PF01946.17 KIR66320.1 - 0.0061 15.8 0.1 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KIR66320.1 - 0.011 14.9 6.6 0.043 12.9 0.1 3.1 4 0 0 4 4 4 0 Lycopene cyclase protein HI0933_like PF03486.14 KIR66320.1 - 0.019 13.7 0.2 0.03 13.0 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KIR66320.1 - 0.032 14.5 0.4 0.079 13.2 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KIR66320.1 - 0.032 14.7 0.1 0.083 13.3 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIR66320.1 - 0.044 13.7 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 KIR66320.1 - 0.044 12.6 0.5 0.066 12.1 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KIR66320.1 - 0.071 13.1 1.1 0.6 10.1 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIR66320.1 - 0.18 10.9 8.5 0.035 13.2 0.8 2.7 3 0 0 3 3 3 0 FAD binding domain Amino_oxidase PF01593.24 KIR66320.1 - 0.42 9.9 5.4 1.6 7.9 0.2 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase SCP2 PF02036.17 KIR66321.1 - 1.1e-09 38.7 0.0 1.6e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family ketoacyl-synt PF00109.26 KIR66322.1 - 2e-51 175.0 8.1 2.7e-51 174.6 3.2 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIR66322.1 - 3e-37 127.2 4.2 5.8e-37 126.3 4.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KIR66322.1 - 6.8e-05 22.4 0.5 0.0049 16.3 0.0 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain DUF3237 PF11578.8 KIR66323.1 - 9.3e-38 129.4 0.0 1e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) p450 PF00067.22 KIR66324.1 - 4.3e-75 253.2 0.0 5.1e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KIR66325.1 - 2.2e-26 93.1 0.0 8.3e-20 71.5 0.2 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR66325.1 - 8.2e-23 82.2 23.9 1.1e-22 81.8 23.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR66325.1 - 1.3e-14 54.1 0.0 1.3e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR66325.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 KIR66325.1 - 2.3e-05 24.7 0.0 2.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KIR66325.1 - 0.0013 17.5 0.0 0.2 10.3 0.0 2.1 2 0 0 2 2 2 2 Ndr family DLH PF01738.18 KIR66325.1 - 0.15 11.6 0.0 8.4 5.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIR66325.1 - 0.16 11.4 0.0 6.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family CLP_protease PF00574.23 KIR66326.1 - 1.7e-72 243.1 0.0 2.1e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 KIR66326.1 - 0.033 14.1 0.2 0.066 13.2 0.1 1.6 2 0 0 2 2 2 0 Peptidase family S49 MFS_1 PF07690.16 KIR66327.1 - 1.4e-46 159.1 49.7 1.7e-45 155.5 42.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR66327.1 - 0.0041 16.0 7.3 0.0041 16.0 7.3 2.5 2 1 1 3 3 3 1 MFS_1 like family DUF4293 PF14126.6 KIR66327.1 - 0.33 11.2 0.1 0.33 11.2 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) SnoaL_2 PF12680.7 KIR66328.1 - 3e-10 40.7 0.3 3.4e-10 40.5 0.3 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KIR66328.1 - 0.00029 21.1 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ldt_C PF17969.1 KIR66328.1 - 0.097 13.4 0.1 0.15 12.8 0.1 1.4 1 0 0 1 1 1 0 L,D-transpeptidase C-terminal domain PsbX PF06596.11 KIR66329.1 - 0.17 11.9 4.9 0.33 11.0 4.9 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Abhydrolase_3 PF07859.13 KIR66330.1 - 2.4e-60 204.0 0.5 3.1e-60 203.7 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIR66330.1 - 1.7e-08 33.8 0.0 3.3e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIR66330.1 - 0.0016 18.0 0.0 0.53 9.7 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KIR66330.1 - 0.22 10.2 0.1 1.6 7.3 0.1 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) zf-FPG_IleRS PF06827.14 KIR66331.1 - 0.0051 16.7 0.3 0.02 14.8 0.3 1.8 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-NADH-PPase PF09297.11 KIR66331.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DNA_RNApol_7kD PF03604.13 KIR66331.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit NOB1_Zn_bind PF08772.11 KIR66331.1 - 0.065 13.4 0.1 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.12 KIR66331.1 - 0.23 11.0 1.3 0.33 10.5 1.3 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding T7SS_ESX_EspC PF10824.8 KIR66332.1 - 4e-08 33.6 3.0 4.3e-08 33.5 3.0 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm WXG100 PF06013.12 KIR66332.1 - 0.0028 17.9 0.2 0.42 10.9 0.0 2.3 2 0 0 2 2 2 2 Proteins of 100 residues with WXG GcpE PF04551.14 KIR66332.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 GcpE protein YbaB_DNA_bd PF02575.16 KIR66333.1 - 2.4e-05 24.5 0.1 3.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family NAD_binding_10 PF13460.6 KIR66334.1 - 4.2e-10 39.8 1.7 2.1e-08 34.3 1.7 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIR66334.1 - 1.1e-05 25.1 0.2 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 KIR66334.1 - 2.5e-05 23.9 0.0 0.00035 20.1 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIR66334.1 - 7.1e-05 22.0 0.1 0.0067 15.6 0.2 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain DapB_N PF01113.20 KIR66334.1 - 0.021 14.9 1.5 0.064 13.4 1.5 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2263 PF10021.9 KIR66334.1 - 0.094 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) Semialdhyde_dh PF01118.24 KIR66334.1 - 0.099 13.1 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydr_30_2 PF14587.6 KIR66335.1 - 4.3e-17 62.8 0.1 2.6e-14 53.6 0.0 2.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 RicinB_lectin_2 PF14200.6 KIR66335.1 - 1.6e-14 54.4 12.1 3e-10 40.7 0.4 4.6 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Big_4 PF07532.11 KIR66335.1 - 1e-13 50.8 4.4 3.6e-07 29.8 0.2 3.3 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 4) F5_F8_type_C PF00754.25 KIR66335.1 - 9.3e-06 25.8 0.1 9.3e-06 25.8 0.1 2.6 2 0 0 2 2 2 1 F5/8 type C domain Ricin_B_lectin PF00652.22 KIR66335.1 - 0.0053 17.0 0.0 0.11 12.8 0.0 2.3 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Cadherin-like PF12733.7 KIR66335.1 - 0.026 15.0 8.4 0.095 13.2 2.7 4.3 2 1 0 2 2 2 0 Cadherin-like beta sandwich domain PDZ_6 PF17820.1 KIR66335.1 - 0.042 13.7 0.0 2.8 7.8 0.0 3.0 2 0 0 2 2 2 0 PDZ domain Glyco_hydro_30C PF17189.4 KIR66335.1 - 0.063 13.5 2.2 0.2 11.9 1.2 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Urease_gamma PF00547.18 KIR66336.1 - 3.5e-45 152.3 0.0 3.9e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 KIR66337.1 - 2e-39 133.6 0.0 2.3e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_1 PF01979.20 KIR66338.1 - 9.4e-69 232.3 0.4 1.2e-68 232.0 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KIR66338.1 - 1.2e-54 183.7 0.3 2e-54 183.0 0.3 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 KIR66338.1 - 2.6e-08 33.8 9.4 1.5e-07 31.3 3.9 2.3 1 1 1 2 2 2 2 Amidohydrolase family Molybdopterin_N PF18364.1 KIR66338.1 - 0.089 12.8 2.0 0.2 11.7 0.3 2.3 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain UreF PF01730.16 KIR66339.1 - 8.2e-24 84.7 4.0 1.3e-23 84.0 4.0 1.3 1 0 0 1 1 1 1 UreF cobW PF02492.19 KIR66340.1 - 4.1e-34 117.7 0.0 4.9e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KIR66340.1 - 3.8e-05 22.8 3.6 0.00061 18.9 3.6 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIR66340.1 - 0.01 16.3 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.14 KIR66340.1 - 0.044 13.7 0.1 0.36 10.7 0.1 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 KIR66340.1 - 0.046 14.2 0.0 0.064 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KIR66340.1 - 0.065 13.3 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KIR66340.1 - 0.12 12.5 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KIR66340.1 - 0.13 12.9 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIR66340.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 KIR66340.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIR66340.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIR66340.1 - 0.2 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KIR66340.1 - 0.23 11.4 0.4 0.52 10.2 0.1 1.7 2 0 0 2 2 2 0 NACHT domain UreD PF01774.17 KIR66341.1 - 6.6e-25 88.3 0.1 7.8e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 UreD urease accessory protein MarR PF01047.22 KIR66342.1 - 7.1e-12 45.1 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR66342.1 - 2.7e-10 40.0 4.3 3.4e-10 39.7 0.1 2.8 3 1 0 3 3 3 1 MarR family HTH_24 PF13412.6 KIR66342.1 - 0.0015 18.1 0.0 0.0046 16.5 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR66342.1 - 0.0068 16.2 1.6 0.033 14.0 0.0 2.5 3 0 0 3 3 3 1 IclR helix-turn-helix domain DUF742 PF05331.11 KIR66342.1 - 0.0076 16.1 1.8 0.025 14.4 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF742) HTH_27 PF13463.6 KIR66342.1 - 0.026 15.0 0.2 0.17 12.4 0.0 2.4 3 0 0 3 3 3 0 Winged helix DNA-binding domain Rrf2 PF02082.20 KIR66342.1 - 0.038 14.3 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR PF03551.14 KIR66342.1 - 0.067 13.2 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_20 PF12840.7 KIR66342.1 - 2.8 8.1 8.2 0.77 9.9 0.9 3.2 2 2 0 2 2 2 0 Helix-turn-helix domain Peripla_BP_6 PF13458.6 KIR66343.1 - 9.1e-68 229.4 1.0 1.1e-67 229.2 1.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 KIR66343.1 - 2.1e-51 175.1 0.0 2.4e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain ANF_receptor PF01094.28 KIR66343.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region BPD_transp_2 PF02653.16 KIR66344.1 - 5.6e-48 163.4 41.9 6.3e-48 163.3 41.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF2304 PF10066.9 KIR66344.1 - 0.91 9.8 0.0 0.91 9.8 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2304) BPD_transp_2 PF02653.16 KIR66345.1 - 7e-33 113.9 29.6 1.2e-32 113.2 29.6 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 KIR66346.1 - 8.8e-32 110.5 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66346.1 - 1.7e-09 37.9 0.2 9.3e-05 22.4 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KIR66346.1 - 0.00019 21.2 1.3 0.00033 20.4 1.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR66346.1 - 0.00081 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR66346.1 - 0.016 15.7 0.0 0.024 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIR66346.1 - 0.029 13.7 0.2 0.068 12.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KIR66346.1 - 0.029 13.9 2.0 0.043 13.4 0.8 1.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIR66346.1 - 0.029 14.6 0.3 0.15 12.4 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR66346.1 - 0.039 14.3 0.8 0.057 13.8 0.8 1.4 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KIR66346.1 - 0.075 12.5 0.0 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KIR66346.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIR66346.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Glycoamylase PF10091.9 KIR66347.1 - 2.3e-14 53.5 0.0 4.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Putative glucoamylase DUF3131 PF11329.8 KIR66347.1 - 5e-10 39.0 0.2 7.1e-10 38.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3131) BPD_transp_1 PF00528.22 KIR66348.1 - 8.3e-21 74.6 13.5 1.6e-20 73.6 13.5 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF3149 PF11346.8 KIR66348.1 - 0.022 14.3 0.1 0.26 10.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) BPD_transp_1 PF00528.22 KIR66349.1 - 2.6e-15 56.6 14.8 2.6e-15 56.6 14.8 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 KIR66350.1 - 1.1e-37 130.7 13.0 1.1e-37 130.7 13.0 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 KIR66350.1 - 1.4e-37 130.0 7.4 1.4e-37 130.0 7.4 1.3 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 KIR66350.1 - 3.8e-07 29.8 0.1 0.019 14.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIR66350.1 - 4.7e-06 26.5 9.1 6.3e-06 26.1 3.8 2.9 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein LPAM_2 PF13627.6 KIR66350.1 - 0.29 11.1 3.2 0.53 10.2 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Kelch_6 PF13964.6 KIR66352.1 - 2.3e-06 27.7 10.4 5.8 7.4 0.1 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KIR66352.1 - 9.8e-06 25.5 12.3 1 9.4 0.2 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain PPV_E2_C PF00511.17 KIR66352.1 - 0.0072 16.5 0.6 44 4.4 0.0 4.4 5 0 0 5 5 5 1 E2 (early) protein, C terminal ABC_membrane PF00664.23 KIR66353.1 - 1.6e-26 93.6 0.0 1.9e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR66353.1 - 3e-24 86.1 0.0 4.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR66353.1 - 0.0011 19.4 3.0 0.0038 17.6 3.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KIR66353.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIR66353.1 - 0.0067 16.7 0.1 0.024 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR66353.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KIR66353.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIR66353.1 - 0.035 14.2 2.0 0.19 11.9 2.0 2.3 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIR66353.1 - 0.037 13.5 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIR66353.1 - 0.065 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KIR66353.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KIR66353.1 - 0.077 12.7 0.3 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 Cytidylate kinase Mg_chelatase PF01078.21 KIR66353.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIR66353.1 - 0.13 11.8 7.7 0.18 11.4 3.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIR66353.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KIR66353.1 - 0.26 11.1 0.1 0.79 9.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TetR_N PF00440.23 KIR66354.1 - 8.3e-14 51.1 0.2 2.4e-13 49.6 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 KIR66354.1 - 4.8e-11 42.6 7.9 4.8e-11 42.6 7.9 1.9 2 0 0 2 2 2 1 MftR C-terminal domain HTH_23 PF13384.6 KIR66354.1 - 0.00033 20.3 0.0 0.00098 18.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 KIR66354.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_AraC PF00165.23 KIR66354.1 - 0.044 13.9 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KIR66354.1 - 0.13 12.5 8.1 0.38 11.0 0.3 3.2 3 1 1 4 4 4 0 Helix-turn-helix domain TetR_C_16 PF17920.1 KIR66354.1 - 0.32 11.3 6.8 0.14 12.4 2.4 2.6 1 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 KIR66355.1 - 2.1e-46 158.5 56.2 2.6e-46 158.2 52.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR66355.1 - 5.3e-12 45.3 38.3 3.8e-11 42.5 11.8 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 KIR66355.1 - 0.00062 18.4 43.4 0.002 16.8 6.1 4.2 3 1 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KIR66355.1 - 0.26 9.6 8.0 1.5 7.0 3.3 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Mak_N_cap PF18085.1 KIR66356.1 - 2.3e-26 92.7 0.3 4.8e-26 91.6 0.3 1.6 1 0 0 1 1 1 1 Maltokinase N-terminal cap domain Response_reg PF00072.24 KIR66359.1 - 4.2e-14 52.7 0.0 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR66359.1 - 1.5e-12 46.9 0.0 2.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR66359.1 - 1.6e-06 27.6 0.0 3.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66359.1 - 0.00075 19.0 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR66359.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 KIR66359.1 - 0.15 12.1 1.0 4.2 7.5 0.1 3.1 2 1 1 3 3 3 0 Winged helix-turn helix HTH_38 PF13936.6 KIR66359.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF397 PF04149.12 KIR66360.1 - 8e-21 73.9 0.9 9e-21 73.7 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) DUF2238 PF09997.9 KIR66361.1 - 9e-57 190.8 0.2 1.6e-56 190.0 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2238) Trep_Strep PF09605.10 KIR66361.1 - 2.9 7.8 7.3 0.25 11.3 1.5 1.9 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DeoC PF01791.9 KIR66362.1 - 3.9e-36 124.8 0.5 4.5e-36 124.6 0.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase PP-binding PF00550.25 KIR66363.1 - 5.9e-10 39.4 0.3 7e-10 39.1 0.3 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1493 PF07377.12 KIR66363.1 - 0.04 14.4 0.0 0.044 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Aminotran_3 PF00202.21 KIR66364.1 - 4e-47 160.8 0.0 3.2e-27 95.2 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIR66364.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II AMP-binding PF00501.28 KIR66365.1 - 1e-30 106.7 6.2 1.4e-21 76.6 0.1 3.0 3 0 0 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 KIR66365.1 - 2.5e-15 57.2 0.7 6.9e-15 55.8 0.7 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_tran_28_C PF04101.16 KIR66366.1 - 3.9e-07 30.2 0.0 6.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 KIR66366.1 - 1.7e-06 27.5 0.0 6.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 1 UDPGT PF00201.18 KIR66366.1 - 0.00097 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 KIR66366.1 - 0.025 14.6 2.1 0.053 13.5 0.3 2.5 2 1 1 3 3 3 0 Glycosyltransferase Family 4 Acyl_transf_1 PF00698.21 KIR66367.1 - 1.4e-31 110.2 0.6 1.7e-31 109.9 0.6 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KIR66367.1 - 0.00041 20.1 1.6 0.0072 16.1 1.6 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short_C2 PF13561.6 KIR66368.1 - 6.4e-56 189.5 8.3 7.2e-56 189.4 8.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66368.1 - 1e-45 155.6 1.6 1.3e-45 155.3 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66368.1 - 8.1e-18 65.0 1.7 1.1e-17 64.5 1.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIR66368.1 - 0.00057 19.4 0.4 0.00085 18.8 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIR66368.1 - 0.00059 19.1 0.0 0.00071 18.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KIR66368.1 - 0.0038 17.3 0.1 0.0064 16.6 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 KIR66368.1 - 0.028 14.0 1.4 0.042 13.4 1.4 1.2 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIR66368.1 - 0.05 13.9 0.3 0.089 13.0 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RGP PF03214.13 KIR66369.1 - 1.6e-12 47.3 0.0 1.5e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Reversibly glycosylated polypeptide Epimerase PF01370.21 KIR66370.1 - 3.6e-51 174.0 0.0 4.7e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR66370.1 - 2.1e-31 109.5 0.0 2e-30 106.4 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIR66370.1 - 1.6e-08 34.6 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIR66370.1 - 3.8e-08 32.7 0.0 5.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIR66370.1 - 4.7e-05 22.7 0.0 0.0096 15.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KIR66370.1 - 0.00013 21.2 0.0 1.7 7.7 0.0 3.2 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NmrA PF05368.13 KIR66370.1 - 0.00091 18.8 0.0 0.0017 18.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KIR66370.1 - 0.13 11.3 0.0 0.76 8.8 0.0 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain Amidohydro_3 PF07969.11 KIR66371.1 - 8.2e-62 210.2 0.6 9.5e-62 210.0 0.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIR66371.1 - 1.3e-06 28.0 0.0 0.026 13.9 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family ABC2_membrane_6 PF06182.11 KIR66372.1 - 4.4e-46 157.5 1.5 5.2e-46 157.3 1.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_6 PF06182.11 KIR66373.1 - 1.1e-28 100.6 7.6 1.4e-28 100.3 7.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 KIR66373.1 - 0.0036 16.7 15.2 0.0058 16.1 15.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KIR66374.1 - 2e-22 80.2 0.0 3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66374.1 - 3.5e-09 36.9 0.1 1.4e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR66374.1 - 0.0039 16.9 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR66374.1 - 0.02 15.3 0.1 0.044 14.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KIR66374.1 - 0.052 13.9 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KIR66374.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIR66374.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 KIR66374.1 - 0.15 12.3 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIR66374.1 - 0.17 12.4 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIR66374.1 - 0.2 11.2 0.1 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Exo_endo_phos PF03372.23 KIR66375.1 - 3.9e-17 62.6 1.7 5.6e-17 62.0 1.7 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF839 PF05787.13 KIR66376.1 - 8.1e-68 229.8 1.8 1e-58 199.8 4.7 2.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF839) Glyoxalase_6 PF18029.1 KIR66377.1 - 6.6e-17 62.3 9.9 4.8e-10 40.2 0.4 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 KIR66377.1 - 0.00062 20.0 0.0 0.095 12.9 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIR66377.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_6 PF12697.7 KIR66378.1 - 6.3e-19 69.5 20.0 7.2e-19 69.3 20.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR66378.1 - 7.2e-10 38.9 0.3 2.5e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR66378.1 - 4.7e-05 22.8 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KIR66378.1 - 0.00015 21.7 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase DUF2974 PF11187.8 KIR66378.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KIR66378.1 - 0.013 15.6 1.4 0.11 12.6 0.8 2.2 1 1 1 2 2 2 0 Thioesterase domain Abhydrolase_5 PF12695.7 KIR66378.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KIR66378.1 - 0.096 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 KIR66378.1 - 0.18 11.4 0.1 0.48 10.0 0.1 1.6 2 0 0 2 2 2 0 Putative esterase Lipase_3 PF01764.25 KIR66378.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAPS_reduct PF01507.19 KIR66379.1 - 1.4e-48 165.2 0.0 1.7e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 KIR66379.1 - 0.055 13.2 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 KIR66379.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ABC_tran PF00005.27 KIR66380.1 - 1e-29 103.8 0.0 1.6e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66380.1 - 6.7e-08 32.7 0.9 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KIR66380.1 - 2.2e-05 24.2 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KIR66380.1 - 0.00093 18.3 0.2 0.0015 17.5 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIR66380.1 - 0.0022 18.4 0.4 0.007 16.8 0.2 1.9 1 1 1 2 2 2 1 AAA ATPase domain Fer4_NifH PF00142.18 KIR66380.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SMC_N PF02463.19 KIR66380.1 - 0.074 12.5 0.0 6.8 6.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR66380.1 - 0.098 13.2 0.6 0.16 12.5 0.6 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR66380.1 - 0.12 12.2 0.2 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4162 PF13732.6 KIR66380.1 - 0.14 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) CLP1_P PF16575.5 KIR66380.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 KIR66380.1 - 0.2 11.7 0.5 0.32 11.0 0.5 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Esterase_phd PF10503.9 KIR66381.1 - 1.5e-15 57.3 0.1 3e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 KIR66381.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KIR66381.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family PQQ_3 PF13570.6 KIR66382.1 - 0.072 13.6 25.2 0.24 12.0 0.4 7.2 7 1 0 7 7 7 0 PQQ-like domain Sulfotransfer_3 PF13469.6 KIR66383.1 - 1.5e-15 58.2 0.1 1.1e-09 39.0 0.0 3.1 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR66383.1 - 6.4e-11 42.2 0.0 4e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 KIR66383.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Abhydrolase_1 PF00561.20 KIR66384.1 - 2.1e-25 89.8 0.0 2.8e-22 79.6 0.0 2.0 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR66384.1 - 7.1e-22 79.1 12.1 8.4e-22 78.9 12.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR66384.1 - 2.7e-20 72.7 0.0 4.2e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIR66384.1 - 4.2e-05 23.8 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 KIR66384.1 - 0.00015 20.5 0.0 0.00041 19.2 0.0 1.5 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 KIR66384.1 - 0.027 14.1 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 KIR66384.1 - 0.036 13.7 0.0 0.08 12.5 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 KIR66384.1 - 0.11 12.2 0.0 1.2 8.8 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIR66384.1 - 0.23 10.9 0.0 2.2 7.7 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 KIR66384.1 - 0.27 10.0 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PP-binding PF00550.25 KIR66385.1 - 7.8e-08 32.6 0.3 1.3e-07 31.9 0.3 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site TauE PF01925.19 KIR66386.1 - 1.4e-34 119.8 37.2 1.4e-34 119.8 37.2 1.6 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE CBM_2 PF00553.19 KIR66387.1 - 1.6e-28 98.9 11.2 1.6e-28 98.9 11.2 2.6 3 0 0 3 3 3 1 Cellulose binding domain Esterase_phd PF10503.9 KIR66387.1 - 1.3e-19 70.5 0.0 1.3e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR66387.1 - 1.8e-08 34.2 0.1 3.3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIR66387.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Na_H_antiport_1 PF06965.12 KIR66388.1 - 3.2e-132 440.9 23.6 3.9e-132 440.7 23.6 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 RhodobacterPufX PF11511.8 KIR66388.1 - 0.81 9.3 6.5 4.5 6.9 0.2 3.5 3 0 0 3 3 3 0 Intrinsic membrane protein PufX SBP_bac_5 PF00496.22 KIR66389.1 - 1.4e-97 327.0 3.7 1.9e-97 326.6 3.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KIR66390.1 - 8e-43 146.3 10.1 8e-43 146.3 10.1 2.2 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR66391.1 - 1.8e-30 106.1 13.3 1.8e-30 106.1 13.3 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KIR66391.1 - 8.8e-05 22.4 0.0 8.8e-05 22.4 0.0 3.5 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 KIR66392.1 - 3.9e-26 92.2 0.0 5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR66392.1 - 6.7e-17 61.8 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR66392.1 - 1.4e-05 25.1 0.0 0.00018 21.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66392.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR66392.1 - 0.018 15.3 0.1 0.049 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIR66392.1 - 0.03 14.1 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KIR66392.1 - 0.12 12.1 0.2 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 KIR66392.1 - 0.26 11.7 1.2 0.53 10.6 1.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KIR66392.1 - 0.95 9.0 3.9 13 5.3 3.9 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIR66393.1 - 7.6e-33 113.9 0.0 1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR66393.1 - 3.9e-17 62.5 0.3 7.5e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR66393.1 - 1.2e-06 28.5 0.0 0.0038 17.1 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66393.1 - 4.7e-05 22.9 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR66393.1 - 0.004 17.5 1.6 0.007 16.8 1.6 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR66393.1 - 0.0077 16.5 0.4 0.056 13.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR66393.1 - 0.011 15.5 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 KIR66393.1 - 0.16 12.3 0.1 0.71 10.1 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KIR66393.1 - 0.17 11.4 2.0 1.2 8.7 2.0 2.2 1 1 0 1 1 1 0 AAA domain Peripla_BP_3 PF13377.6 KIR66394.1 - 9.2e-42 143.2 0.8 2e-41 142.1 0.8 1.6 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66394.1 - 3e-27 95.8 0.0 3.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR66394.1 - 5.7e-17 62.1 0.0 7.7e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 KIR66394.1 - 7.7e-12 44.8 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 KIR66394.1 - 0.00013 22.2 0.6 0.00013 22.2 0.6 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66394.1 - 0.0081 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix Peripla_BP_6 PF13458.6 KIR66394.1 - 0.024 14.3 0.2 0.77 9.4 0.0 2.2 1 1 0 2 2 2 0 Periplasmic binding protein HTH_23 PF13384.6 KIR66394.1 - 0.028 14.2 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 KIR66394.1 - 0.038 13.8 0.2 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 KIR66394.1 - 0.041 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KIR66394.1 - 0.044 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KIR66394.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain TetR_N PF00440.23 KIR66394.1 - 0.11 12.3 2.6 0.23 11.3 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family FGGY_C PF02782.16 KIR66395.1 - 4.9e-43 147.2 4.7 7.3e-43 146.6 4.7 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIR66395.1 - 1.3e-11 44.6 0.0 7.2e-11 42.1 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain AnmK PF03702.14 KIR66395.1 - 0.037 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase IU_nuc_hydro PF01156.19 KIR66395.1 - 0.099 12.2 0.5 0.17 11.4 0.5 1.3 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Peripla_BP_4 PF13407.6 KIR66396.1 - 7.8e-51 173.1 8.2 9.7e-51 172.8 8.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KIR66396.1 - 1.3e-16 60.9 0.6 1.9e-16 60.3 0.6 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 KIR66396.1 - 8.6e-09 35.9 0.0 1.5e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain ABC_sub_bind PF04392.12 KIR66396.1 - 1.7e-05 24.2 0.2 3.4e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_6 PF13458.6 KIR66396.1 - 0.0019 17.9 3.3 0.006 16.3 3.0 1.8 1 1 1 2 2 2 2 Periplasmic binding protein Helicase_C PF00271.31 KIR66396.1 - 0.028 14.8 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain ABC_tran PF00005.27 KIR66397.1 - 5.4e-53 179.2 0.0 5.8e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR66397.1 - 1.6e-13 51.2 0.1 0.00027 20.8 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66397.1 - 0.00038 19.9 0.3 0.0034 16.8 0.4 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KIR66397.1 - 0.00052 20.2 0.4 0.045 14.0 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIR66397.1 - 0.0012 18.5 0.1 0.0046 16.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR66397.1 - 0.0018 18.2 0.1 0.0097 15.8 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KIR66397.1 - 0.003 17.3 6.4 0.0033 17.2 2.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIR66397.1 - 0.0077 16.5 3.3 0.14 12.4 1.3 3.4 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIR66397.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR66397.1 - 0.011 16.1 0.9 0.44 10.9 0.1 3.1 3 1 0 3 3 3 0 AAA ATPase domain TsaE PF02367.17 KIR66397.1 - 0.02 14.9 0.5 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIR66397.1 - 0.056 13.2 0.0 0.3 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 KIR66397.1 - 0.069 12.9 0.1 9.8 5.9 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KIR66397.1 - 0.087 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 KIR66397.1 - 0.11 11.1 0.7 7.8 5.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIR66397.1 - 0.12 11.6 1.0 1.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin FeoB_N PF02421.18 KIR66397.1 - 0.32 10.5 1.7 5.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 KIR66397.1 - 0.34 10.5 5.8 1.2 8.7 0.0 3.4 3 1 1 4 4 4 0 AAA domain BPD_transp_2 PF02653.16 KIR66398.1 - 3.6e-42 144.4 43.2 5e-42 143.9 43.2 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF2434 PF10361.9 KIR66398.1 - 0.041 12.9 0.7 0.095 11.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) BPD_transp_2 PF02653.16 KIR66399.1 - 8e-46 156.4 44.6 1.3e-45 155.7 44.6 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Arabinose_Isome PF02610.15 KIR66400.1 - 3.1e-170 566.2 0.0 3.6e-170 565.9 0.0 1.0 1 0 0 1 1 1 1 L-arabinose isomerase Arabinose_Iso_C PF11762.8 KIR66400.1 - 1.5e-47 160.1 0.0 1.3e-46 157.1 0.0 2.6 3 0 0 3 3 3 1 L-arabinose isomerase C-terminal domain fn3_2 PF16893.5 KIR66400.1 - 0.038 14.1 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain Peripla_BP_3 PF13377.6 KIR66401.1 - 2.7e-39 135.2 1.1 1.1e-38 133.1 0.1 2.2 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66401.1 - 1.7e-22 80.2 0.0 2.3e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR66401.1 - 2.9e-22 78.2 0.4 6.6e-22 77.1 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR66401.1 - 1.8e-16 60.5 0.0 3.1e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 KIR66401.1 - 0.0097 15.3 0.1 0.042 13.3 0.1 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 KIR66401.1 - 0.011 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 KIR66401.1 - 0.048 14.0 0.2 0.048 14.0 0.2 3.3 3 1 1 4 4 4 0 Helix-turn-helix domain HTH_38 PF13936.6 KIR66401.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR66401.1 - 0.079 13.0 0.4 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain SelB-wing_3 PF09107.11 KIR66401.1 - 0.14 11.8 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Aminotran_1_2 PF00155.21 KIR66402.1 - 7.3e-18 64.9 0.0 9.5e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 KIR66402.1 - 2.9e-12 46.0 1.7 7.8e-12 44.7 1.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 KIR66402.1 - 0.00011 22.0 2.0 0.00011 22.0 2.0 2.8 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 KIR66402.1 - 0.0032 17.8 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 KIR66402.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 MarR family DegT_DnrJ_EryC1 PF01041.17 KIR66402.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_Crp_2 PF13545.6 KIR66402.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 KIR66402.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KIR66402.1 - 1.3 8.9 6.2 0.13 12.1 0.7 2.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain Pec_lyase_C PF00544.19 KIR66403.1 - 4e-34 118.0 5.8 6e-34 117.5 5.8 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIR66403.1 - 0.0023 17.8 25.2 0.022 14.6 5.8 3.0 2 1 2 4 4 4 3 Right handed beta helix region F5_F8_type_C PF00754.25 KIR66403.1 - 0.023 14.8 1.7 0.067 13.3 0.1 2.4 2 0 0 2 2 2 0 F5/8 type C domain Amidase PF01425.21 KIR66405.1 - 4.4e-73 246.8 6.5 2.5e-68 231.1 5.1 2.2 1 1 1 2 2 2 2 Amidase FMN_red PF03358.15 KIR66406.1 - 6.4e-34 116.9 0.0 8.9e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIR66406.1 - 5.9e-06 26.1 0.0 7.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KIR66406.1 - 0.074 13.3 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain DAGK_cat PF00781.24 KIR66407.1 - 8e-20 70.7 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peripla_BP_6 PF13458.6 KIR66407.1 - 0.00086 19.1 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein PEGA PF08308.11 KIR66407.1 - 0.19 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 PEGA domain PhoD PF09423.10 KIR66408.1 - 9.2e-116 386.7 0.1 1.1e-115 386.4 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KIR66408.1 - 2.6e-30 104.8 0.4 5.8e-30 103.7 0.4 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KIR66408.1 - 0.00029 21.3 0.0 0.0008 19.9 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 KIR66408.1 - 0.017 15.6 0.0 5.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Amidohydro_2 PF04909.14 KIR66409.1 - 1.7e-07 31.3 5.9 3.3e-07 30.4 5.9 1.7 1 1 0 1 1 1 1 Amidohydrolase GFO_IDH_MocA PF01408.22 KIR66410.1 - 1.4e-22 80.8 1.7 2.5e-22 80.0 1.7 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR66410.1 - 0.0045 17.0 0.0 0.017 15.1 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.6 KIR66410.1 - 0.048 14.2 4.7 0.055 14.0 3.0 2.0 2 0 0 2 2 2 0 CoA binding domain CoA_binding PF02629.19 KIR66410.1 - 4.3 8.1 5.7 0.45 11.2 0.6 2.1 2 1 0 2 2 2 0 CoA binding domain BPD_transp_1 PF00528.22 KIR66411.1 - 4.7e-12 46.0 20.9 4.7e-12 46.0 20.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR66412.1 - 2e-18 66.8 16.5 2e-18 66.8 16.5 1.9 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MotA_ExbB PF01618.16 KIR66412.1 - 0.21 11.3 1.7 16 5.3 0.1 2.4 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family E1_dh PF00676.20 KIR66413.1 - 3e-69 233.3 0.0 3.6e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KIR66413.1 - 2.8e-08 33.7 3.0 6.9e-08 32.4 0.7 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KIR66413.1 - 1.4e-06 27.7 0.5 2.1e-06 27.1 0.5 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.21 KIR66413.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Mst1_SARAH PF11629.8 KIR66413.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Transket_pyr PF02779.24 KIR66414.1 - 2.4e-42 144.6 0.1 5.1e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIR66414.1 - 5.9e-40 136.0 0.6 9.7e-40 135.3 0.6 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain MarR_2 PF12802.7 KIR66415.1 - 0.00045 20.1 3.8 0.00051 19.9 0.6 2.8 3 0 0 3 3 3 1 MarR family HTH_11 PF08279.12 KIR66415.1 - 0.016 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 KIR66415.1 - 0.13 12.4 2.3 0.85 9.8 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain YCII PF03795.14 KIR66416.1 - 7.3e-11 42.3 0.8 1e-10 41.8 0.8 1.1 1 0 0 1 1 1 1 YCII-related domain Phage_holin_7_1 PF16081.5 KIR66418.1 - 0.14 12.4 3.9 0.22 11.7 3.9 1.4 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF983 PF06170.12 KIR66418.1 - 0.6 10.5 5.2 0.24 11.9 2.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Ammonium_transp PF00909.21 KIR66418.1 - 1.2 7.7 11.1 1.5 7.5 5.9 2.5 1 1 1 2 2 2 0 Ammonium Transporter Family DUF4231 PF14015.6 KIR66418.1 - 2.3 8.7 8.1 1.9 9.0 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) YIEGIA PF14045.6 KIR66418.1 - 4.4 6.1 6.3 30 3.3 0.6 2.0 1 1 1 2 2 2 0 YIEGIA protein FA_hydroxylase PF04116.13 KIR66419.1 - 1e-26 93.8 12.3 1e-26 93.8 12.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GntR PF00392.21 KIR66420.1 - 4.4e-22 77.5 0.8 1.3e-21 76.0 0.3 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 KIR66420.1 - 1.1e-10 42.0 6.4 1.1e-10 42.0 6.4 2.0 2 0 0 2 2 2 1 FCD domain MarR_2 PF12802.7 KIR66420.1 - 0.0017 18.2 0.9 0.0017 18.2 0.9 2.5 3 0 0 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KIR66420.1 - 0.0021 18.0 0.2 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 KIR66420.1 - 0.014 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PaaX PF07848.12 KIR66420.1 - 0.02 15.1 1.2 0.056 13.7 0.8 1.9 2 0 0 2 2 2 0 PaaX-like protein TrmB PF01978.19 KIR66420.1 - 0.034 14.0 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_rep_org_N PF09681.10 KIR66420.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) MarR PF01047.22 KIR66420.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF4423 PF14394.6 KIR66420.1 - 0.24 11.1 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_28 PF13518.6 KIR66420.1 - 0.64 10.2 5.3 2.5 8.3 0.2 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain CDP-OH_P_transf PF01066.21 KIR66421.1 - 2.2e-07 31.6 3.8 2.2e-07 31.6 3.8 2.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF826 PF05696.11 KIR66421.1 - 0.19 11.8 0.2 0.38 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF826) 3HCDH_N PF02737.18 KIR66422.1 - 0.00014 21.9 0.4 0.00023 21.1 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIR66422.1 - 0.00036 20.5 0.2 0.0012 18.9 0.2 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KIR66422.1 - 0.0013 18.1 0.3 0.0019 17.5 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR66422.1 - 0.0019 18.4 0.8 0.0044 17.2 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIR66422.1 - 0.0033 17.1 1.8 0.0052 16.4 1.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 KIR66422.1 - 0.0045 17.3 0.1 0.0075 16.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 KIR66422.1 - 0.0073 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 KIR66422.1 - 0.0074 15.9 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KIR66422.1 - 0.0094 15.3 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KIR66422.1 - 0.043 13.4 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KIR66422.1 - 0.053 14.1 0.3 0.096 13.3 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KIR66422.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIR66422.1 - 0.12 11.7 0.8 0.18 11.1 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KIR66422.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PTPS PF01242.19 KIR66423.1 - 5.1e-21 74.9 0.0 5.7e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase GTP_cyclohydro2 PF00925.20 KIR66424.1 - 3e-60 202.5 0.0 3.6e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase II ADH_zinc_N PF00107.26 KIR66424.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ERAP1_C PF11838.8 KIR66424.1 - 0.074 12.6 0.3 0.1 12.1 0.3 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain MerR_1 PF13411.6 KIR66425.1 - 1.5e-25 89.1 0.1 3e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 MerR HTH family regulatory protein MerR PF00376.23 KIR66425.1 - 3.3e-21 74.7 15.7 5.4e-12 45.3 1.0 3.8 4 0 0 4 4 4 2 MerR family regulatory protein HTH_3 PF01381.22 KIR66425.1 - 3.5e-06 27.0 0.0 0.071 13.2 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix HTH_Tnp_1 PF01527.20 KIR66425.1 - 1.4e-05 25.3 0.3 0.18 12.1 0.0 3.4 3 0 0 3 3 3 2 Transposase HTH_17 PF12728.7 KIR66425.1 - 0.00027 21.0 1.4 0.055 13.7 0.0 3.3 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_28 PF13518.6 KIR66425.1 - 0.0068 16.5 2.6 2.1 8.5 0.1 3.4 3 0 0 3 3 3 2 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR66425.1 - 0.0097 15.8 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT AbiEi_4 PF13338.6 KIR66425.1 - 0.02 15.1 5.8 1 9.6 0.1 3.8 4 1 0 4 4 3 0 Transcriptional regulator, AbiEi antitoxin HTH_23 PF13384.6 KIR66425.1 - 0.027 14.3 5.1 0.27 11.1 0.0 3.7 4 0 0 4 4 4 0 Homeodomain-like domain DUF2259 PF10016.9 KIR66425.1 - 0.054 13.4 0.6 0.31 11.0 0.1 2.3 2 1 0 2 2 2 0 Predicted secreted protein (DUF2259) MarR_2 PF12802.7 KIR66425.1 - 0.084 12.8 5.3 3.2 7.7 0.1 3.8 4 0 0 4 4 4 0 MarR family Rrf2 PF02082.20 KIR66425.1 - 0.096 13.0 0.1 0.74 10.2 0.0 2.6 2 1 1 3 3 3 0 Transcriptional regulator DUF615 PF04751.14 KIR66425.1 - 0.12 12.3 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF615) HTH_29 PF13551.6 KIR66425.1 - 0.23 11.5 4.1 1.7 8.7 0.0 3.8 4 1 0 4 4 4 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 KIR66425.1 - 0.28 10.6 2.0 0.43 10.0 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 KIR66425.1 - 2.2 8.7 20.7 1.6 9.2 0.3 4.2 3 2 1 4 4 4 0 Helix-turn-helix domain AMP-binding PF00501.28 KIR66426.1 - 2.4e-80 270.2 0.3 3.5e-80 269.7 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR66426.1 - 7.5e-29 100.7 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KIR66426.1 - 3.2e-10 40.8 0.5 2.6e-09 37.9 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR66426.1 - 6.4e-10 39.3 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KIR66427.1 - 1.5e-92 310.4 0.1 2.3e-92 309.8 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR66427.1 - 2.7e-28 98.9 0.0 6.6e-28 97.6 0.0 1.5 2 0 0 2 2 2 1 Condensation domain AMP-binding_C PF13193.6 KIR66427.1 - 1e-11 45.6 0.1 8e-11 42.8 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR66427.1 - 3.4e-09 36.9 0.0 9.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KIR66428.1 - 1.5e-92 310.4 0.1 2.2e-92 309.8 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KIR66428.1 - 2.6e-28 98.9 0.0 6.5e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 Condensation domain AMP-binding_C PF13193.6 KIR66428.1 - 1.1e-11 45.6 0.1 7.9e-11 42.8 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 KIR66428.1 - 3.8e-09 36.8 0.0 9.8e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ABC_tran PF00005.27 KIR66430.1 - 7.8e-30 104.2 0.0 1e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66430.1 - 3.6e-10 40.1 0.0 9.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66430.1 - 1.9e-07 30.7 0.0 0.004 16.6 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIR66430.1 - 1.7e-06 28.0 0.0 1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 KIR66430.1 - 1.2e-05 25.8 0.4 3.3e-05 24.3 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 KIR66430.1 - 4.4e-05 22.5 0.0 0.015 14.1 0.0 2.3 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_27 PF13514.6 KIR66430.1 - 6.6e-05 22.6 0.0 0.00044 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2813 PF11398.8 KIR66430.1 - 0.00018 20.9 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_29 PF13555.6 KIR66430.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KIR66430.1 - 0.00052 20.6 0.0 0.00084 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR66430.1 - 0.002 18.4 0.1 0.007 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIR66430.1 - 0.0023 18.2 0.1 0.0064 16.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIR66430.1 - 0.0077 16.4 0.1 0.016 15.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KIR66430.1 - 0.011 15.4 0.1 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 KIR66430.1 - 0.013 14.4 0.0 0.028 13.2 0.0 1.5 1 1 0 1 1 1 0 Adenovirus IVa2 protein AAA_14 PF13173.6 KIR66430.1 - 0.016 15.2 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIR66430.1 - 0.031 13.9 0.1 0.095 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR66430.1 - 0.048 13.6 0.1 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KIR66430.1 - 0.074 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIR66430.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KIR66430.1 - 0.092 13.2 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIR66430.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KIR66430.1 - 0.12 12.5 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIR66430.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase FecCD PF01032.18 KIR66431.1 - 4.2e-71 239.5 33.3 5.1e-71 239.2 33.3 1.1 1 0 0 1 1 1 1 FecCD transport family Aa_trans PF01490.18 KIR66431.1 - 7.1 5.2 7.6 12 4.5 7.6 1.3 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein FecCD PF01032.18 KIR66432.1 - 1.8e-86 290.0 34.2 2.3e-86 289.7 34.2 1.0 1 0 0 1 1 1 1 FecCD transport family Kelch_1 PF01344.25 KIR66432.1 - 0.56 9.8 3.7 0.75 9.4 0.1 2.7 3 0 0 3 3 3 0 Kelch motif Peripla_BP_2 PF01497.18 KIR66433.1 - 5.8e-16 58.8 0.6 8.1e-16 58.3 0.6 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Pyridoxal_deC PF00282.19 KIR66434.1 - 1e-60 205.5 0.0 1.3e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIR66434.1 - 2.5e-05 23.4 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIR66434.1 - 0.001 18.5 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 KIR66434.1 - 0.0042 15.8 0.0 0.0061 15.3 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS K_oxygenase PF13434.6 KIR66435.1 - 7.3e-123 410.0 0.0 9.4e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIR66435.1 - 5.5e-08 32.4 0.0 4.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR66435.1 - 4.5e-06 26.2 0.0 0.0006 19.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ArabFuran-catal PF09206.11 KIR66436.1 - 7e-146 485.5 8.9 1e-145 485.0 8.9 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic RicinB_lectin_2 PF14200.6 KIR66436.1 - 4e-33 114.0 32.2 7.3e-15 55.5 4.4 4.3 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66436.1 - 7.1e-30 103.9 15.6 1.4e-29 102.9 15.6 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain ET PF01684.16 KIR66436.1 - 0.78 10.1 5.2 31 5.0 0.5 3.3 1 1 2 3 3 3 0 ET module Phage_capsid PF05065.13 KIR66437.1 - 0.0013 18.1 0.0 0.0047 16.3 0.0 1.8 1 1 0 1 1 1 1 Phage capsid family Methyltransf_31 PF13847.6 KIR66438.1 - 7.2e-19 68.1 0.0 9.2e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR66438.1 - 1e-17 64.6 0.0 3e-17 63.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR66438.1 - 1.5e-17 64.0 0.0 3.9e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR66438.1 - 1.3e-13 50.9 0.0 2.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KIR66438.1 - 6.9e-12 45.2 0.0 9.9e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KIR66438.1 - 1.3e-11 44.7 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66438.1 - 1e-07 32.6 0.0 2.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIR66438.1 - 2.8e-05 23.8 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KIR66438.1 - 0.00091 18.8 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KIR66438.1 - 0.0095 15.4 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.11 KIR66438.1 - 0.077 11.9 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 KIR66438.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short_C2 PF13561.6 KIR66439.1 - 1.4e-38 132.8 3.7 1.7e-38 132.5 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66439.1 - 3.6e-33 114.7 0.1 6.1e-33 113.9 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIR66439.1 - 1.6e-06 28.2 1.0 3.2e-06 27.2 1.0 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KIR66439.1 - 0.064 13.9 0.3 0.13 12.8 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KIR66439.1 - 0.086 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIR66439.1 - 0.15 11.9 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sulfotransfer_3 PF13469.6 KIR66440.1 - 2.2e-08 34.7 0.1 2.4e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR66440.1 - 1.3e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain MFS_1 PF07690.16 KIR66441.1 - 4.1e-43 147.6 54.8 2.2e-25 89.4 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR66441.1 - 1.4e-06 27.5 10.8 1.4e-06 27.5 10.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIR66441.1 - 3.5e-05 22.8 8.0 3.5e-05 22.8 8.0 2.1 2 0 0 2 2 2 1 MFS_1 like family MFS_5 PF05631.14 KIR66441.1 - 0.0001 21.4 4.0 0.012 14.5 0.3 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 KIR66441.1 - 0.00047 18.7 14.5 0.00047 18.7 14.5 2.8 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_4 PF06779.14 KIR66441.1 - 0.03 13.6 40.1 0.041 13.2 40.1 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 KIR66441.1 - 3.8 6.2 9.0 1.6 7.4 2.5 2.1 2 0 0 2 2 2 0 LacY proton/sugar symporter DegT_DnrJ_EryC1 PF01041.17 KIR66442.1 - 1.4e-59 202.2 0.0 1.9e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIR66442.1 - 6.7e-06 25.5 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIR66442.1 - 9.3e-06 25.1 0.0 7.9e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIR66442.1 - 0.014 14.0 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ABC_tran PF00005.27 KIR66444.1 - 6.8e-23 81.7 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KIR66444.1 - 2.2e-15 57.0 0.0 2.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 KIR66444.1 - 0.0082 15.9 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KIR66444.1 - 0.019 15.2 0.2 0.35 11.0 0.0 2.8 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 KIR66444.1 - 0.031 13.9 3.4 0.05 13.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIR66444.1 - 0.043 14.1 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KIR66444.1 - 0.05 13.0 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KIR66444.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KIR66444.1 - 0.16 12.4 6.4 0.13 12.7 1.5 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIR66444.1 - 0.19 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain LANC_like PF05147.13 KIR66447.1 - 1.2e-13 50.4 2.4 1.1e-06 27.5 0.0 4.3 3 2 1 4 4 4 3 Lanthionine synthetase C-like protein Pkinase PF00069.25 KIR66447.1 - 1.8e-10 40.6 0.0 2.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIR66447.1 - 4e-05 23.7 15.8 0.00018 21.5 0.3 3.4 2 2 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KIR66447.1 - 0.00074 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIR66447.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KIR66447.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 KIR66447.1 - 0.28 10.4 0.0 0.43 9.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like PGI PF00342.19 KIR66448.1 - 1.3e-213 710.0 0.0 1.5e-213 709.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase AAA_5 PF07728.14 KIR66451.1 - 6.2e-35 120.2 0.0 9.7e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIR66451.1 - 7.2e-06 26.5 0.1 1.7e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIR66451.1 - 0.00031 21.2 0.0 0.00093 19.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KIR66451.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KIR66451.1 - 0.00076 19.3 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIR66451.1 - 0.00077 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 KIR66451.1 - 0.0066 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KIR66451.1 - 0.012 15.0 0.0 0.042 13.2 0.0 1.8 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIR66451.1 - 0.013 15.0 0.2 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIR66451.1 - 0.063 13.8 0.0 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIR66451.1 - 0.071 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 KIR66451.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 KIR66451.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KIR66451.1 - 0.19 11.2 0.1 0.64 9.4 0.0 1.8 1 1 1 2 2 2 0 PhoH-like protein FAD_binding_2 PF00890.24 KIR66452.1 - 3.8e-112 375.4 7.4 4.3e-112 375.2 7.4 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR66452.1 - 1.3e-08 34.8 5.9 3.1e-08 33.6 5.9 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIR66452.1 - 2.7e-08 33.6 0.0 4.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR66452.1 - 9.5e-07 29.0 0.2 3.2e-06 27.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR66452.1 - 4e-06 26.3 0.2 0.00016 21.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR66452.1 - 7.6e-06 25.3 0.4 1.6e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIR66452.1 - 1.1e-05 24.3 0.4 1.1e-05 24.3 0.4 2.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KIR66452.1 - 0.00035 19.9 0.3 0.003 16.8 0.2 2.3 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 KIR66452.1 - 0.00037 19.9 0.1 0.00063 19.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIR66452.1 - 0.00067 19.0 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KIR66452.1 - 0.0014 17.7 2.9 0.0031 16.6 2.9 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KIR66452.1 - 0.18 11.7 0.2 0.29 11.0 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KIR66452.1 - 0.18 11.0 0.3 0.3 10.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-ribbon_3 PF13248.6 KIR66453.1 - 0.031 13.7 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TPR_19 PF14559.6 KIR66453.1 - 0.068 13.7 1.1 0.17 12.4 1.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M28 PF04389.17 KIR66454.1 - 1.2e-43 149.2 0.0 2e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF5013 PF16405.5 KIR66454.1 - 0.0077 16.5 0.3 0.033 14.5 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5013) Peptidase_M20 PF01546.28 KIR66454.1 - 3.4 7.3 9.2 3.1 7.4 7.9 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Oxidored_molyb PF00174.19 KIR66455.1 - 8.5e-48 162.2 0.0 1.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain SBP56 PF05694.11 KIR66457.1 - 1e-200 667.4 0.0 1.1e-200 667.2 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KIR66457.1 - 7.4e-06 25.4 0.0 0.086 12.1 0.0 3.1 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller LVIVD PF08309.11 KIR66457.1 - 0.16 11.3 0.0 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 LVIVD repeat NUDIX PF00293.28 KIR66458.1 - 2.3e-14 53.6 0.2 2.8e-14 53.3 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain DZR PF12773.7 KIR66458.1 - 0.041 13.9 0.8 0.066 13.2 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KIR66458.1 - 2.6 7.6 5.4 6.6 6.3 5.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KIR66458.1 - 2.6 7.8 6.7 13 5.5 6.7 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF1768 PF08719.11 KIR66459.1 - 1.4e-52 178.2 0.0 1.6e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF4129 PF13559.6 KIR66459.1 - 0.03 14.6 3.0 0.31 11.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) AHSA1 PF08327.11 KIR66460.1 - 2.4e-12 47.2 0.0 3.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KIR66460.1 - 0.00032 21.0 2.5 0.0005 20.4 1.2 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIR66460.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport YCII PF03795.14 KIR66461.1 - 2.9e-10 40.4 0.0 3.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Sigma70_r2 PF04542.14 KIR66462.1 - 1.7e-11 43.7 1.8 2.4e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR66462.1 - 2.3e-10 40.0 0.1 8.9e-10 38.1 0.1 2.1 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66462.1 - 9.3e-05 21.9 0.0 0.0095 15.4 0.0 2.9 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_2 PF07719.17 KIR66462.1 - 0.011 15.8 5.4 0.11 12.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sigma70_ECF PF07638.11 KIR66462.1 - 0.017 15.0 0.8 0.13 12.1 0.1 2.6 2 2 1 3 3 3 0 ECF sigma factor TPR_8 PF13181.6 KIR66462.1 - 0.047 13.9 0.2 0.87 10.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIR66462.1 - 3.2 8.1 15.2 0.24 11.7 3.4 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat ABC_membrane PF00664.23 KIR66463.1 - 1.2e-38 133.4 6.5 1.5e-38 133.0 6.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIR66463.1 - 3.9e-32 111.6 0.0 6.6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIR66463.1 - 5.3e-05 22.8 0.2 0.0056 16.1 0.0 2.4 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR66463.1 - 0.00033 21.1 0.9 0.00096 19.6 0.9 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR66463.1 - 0.0036 17.6 0.7 0.059 13.6 0.7 2.3 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 KIR66463.1 - 0.011 15.9 0.7 0.057 13.5 1.0 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KIR66463.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_membrane_2 PF06472.15 KIR66463.1 - 0.018 14.5 3.2 0.029 13.8 3.2 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 DEAD PF00270.29 KIR66463.1 - 0.018 14.8 0.1 0.094 12.5 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_33 PF13671.6 KIR66463.1 - 0.024 14.8 0.9 0.096 12.8 0.9 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KIR66463.1 - 0.032 14.4 2.1 0.28 11.4 0.6 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIR66463.1 - 0.039 13.7 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane_3 PF13748.6 KIR66463.1 - 0.18 11.0 10.1 0.48 9.6 10.1 1.7 1 1 0 1 1 1 0 ABC transporter transmembrane region DIM PF08194.12 KIR66463.1 - 0.2 11.9 1.7 37 4.6 0.0 2.8 2 0 0 2 2 2 0 DIM protein Acetyltransf_3 PF13302.7 KIR66464.1 - 5e-31 108.2 0.0 5.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR66464.1 - 3.4e-06 27.3 0.0 4.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIR66464.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GntR PF00392.21 KIR66466.1 - 7.6e-16 57.5 0.1 8.6e-16 57.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 KIR66466.1 - 4.2e-05 23.1 0.0 5.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain adh_short PF00106.25 KIR66467.1 - 1.9e-33 115.6 3.4 2.6e-33 115.1 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR66467.1 - 3.4e-24 85.7 1.5 4.1e-24 85.4 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KIR66467.1 - 5.7e-07 29.6 1.9 8.3e-07 29.1 1.9 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIR66467.1 - 3.1e-06 26.8 1.2 4.7e-06 26.2 1.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIR66467.1 - 1.1e-05 25.4 2.2 0.00011 22.2 2.2 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KIR66467.1 - 0.0014 17.8 0.5 0.0021 17.2 0.5 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Radical_SAM PF04055.21 KIR66468.1 - 7.3e-06 26.5 0.0 1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KIR66468.1 - 0.00023 21.5 0.0 0.00037 20.8 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIR66468.1 - 0.00088 19.4 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Nuc_deoxyrib_tr PF05014.15 KIR66469.1 - 1.2e-06 28.6 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Nuc_deoxyri_tr2 PF15891.5 KIR66469.1 - 2e-05 24.9 0.0 2.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like HisG PF01634.18 KIR66470.1 - 1.3e-15 57.7 0.0 1.9e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Thymidylat_synt PF00303.19 KIR66471.1 - 1.7e-08 33.9 0.0 2.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase Dor1 PF04124.12 KIR66472.1 - 0.099 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family DUF4381 PF14316.6 KIR66474.1 - 0.00028 21.2 0.9 0.0003 21.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) GRA6 PF05084.13 KIR66474.1 - 0.0048 16.9 0.1 0.0054 16.7 0.1 1.1 1 0 0 1 1 1 1 Granule antigen protein (GRA6) BatD PF13584.6 KIR66474.1 - 0.0078 15.1 0.7 0.008 15.0 0.7 1.0 1 0 0 1 1 1 1 Oxygen tolerance TauE PF01925.19 KIR66474.1 - 0.0096 15.6 0.0 0.0096 15.6 0.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4307 PF14155.6 KIR66474.1 - 0.01 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) FeoB_associated PF12669.7 KIR66474.1 - 0.035 14.5 0.7 0.051 14.0 0.7 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2905 PF11146.8 KIR66474.1 - 0.1 12.8 0.5 0.13 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) CcmH PF03918.14 KIR66474.1 - 0.1 11.9 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF3301 PF11743.8 KIR66474.1 - 0.15 11.7 2.7 0.31 10.7 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) FixQ PF05545.11 KIR66474.1 - 0.16 11.9 0.3 0.16 11.9 0.3 1.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF5385 PF17359.2 KIR66474.1 - 0.23 11.0 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Glyco_hydro_42M PF08532.10 KIR66475.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain NTP_transferase PF00483.23 KIR66476.1 - 4.8e-40 137.7 0.0 6.6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIR66476.1 - 2e-08 34.8 2.8 2e-08 34.8 2.8 2.4 2 1 0 2 2 2 1 MobA-like NTP transferase domain DIOX_N PF14226.6 KIR66477.1 - 6.9e-21 75.2 0.0 9.5e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIR66477.1 - 1.3e-10 41.7 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBM_2 PF00553.19 KIR66478.1 - 1.1e-26 93.0 11.5 1.1e-26 93.0 11.5 2.1 3 0 0 3 3 3 1 Cellulose binding domain HD_4 PF13328.6 KIR66479.1 - 3.7e-12 46.3 0.8 6.2e-12 45.5 0.8 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.22 KIR66479.1 - 0.11 12.7 2.1 0.22 11.8 2.1 1.6 1 1 0 1 1 1 0 HD domain AAA_16 PF13191.6 KIR66480.1 - 2.5e-05 24.7 0.4 0.00012 22.5 0.4 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KIR66480.1 - 0.0058 16.6 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 KIR66480.1 - 0.061 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIR66480.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain SNARE_assoc PF09335.11 KIR66481.1 - 4.1e-19 69.2 7.0 9.4e-19 68.1 7.0 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PsbJ PF01788.17 KIR66481.1 - 0.15 12.0 0.7 0.15 12.0 0.7 2.8 3 0 0 3 3 3 0 PsbJ Pec_lyase_C PF00544.19 KIR66482.1 - 1.8e-43 148.6 0.3 2.6e-43 148.1 0.3 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIR66482.1 - 0.0044 16.9 0.3 0.02 14.7 0.3 2.1 1 1 0 1 1 1 1 Right handed beta helix region GFO_IDH_MocA PF01408.22 KIR66483.1 - 1.3e-20 74.5 0.1 2.1e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KIR66483.1 - 0.00097 19.8 0.1 0.0019 18.8 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KIR66483.1 - 0.0017 18.9 0.8 0.0017 18.9 0.8 2.2 2 1 0 2 2 2 1 CoA binding domain Mannitol_dh_C PF08125.13 KIR66484.1 - 2.9e-63 213.6 0.0 4e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KIR66484.1 - 1.6e-32 112.8 0.0 2.9e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain MR_MLE_C PF13378.6 KIR66485.1 - 1.6e-54 184.8 2.8 3e-54 183.9 2.8 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR66485.1 - 2.6e-06 27.6 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UxaC PF02614.14 KIR66486.1 - 7.3e-72 242.7 0.0 9e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Glucuronate isomerase GFO_IDH_MocA_C PF02894.17 KIR66487.1 - 1.4e-18 67.0 0.5 7.1e-18 64.7 0.1 2.3 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KIR66487.1 - 4.1e-18 66.4 1.0 6e-18 65.8 0.4 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KIR66487.1 - 0.00051 20.7 0.4 0.00087 19.9 0.4 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peripla_BP_3 PF13377.6 KIR66488.1 - 2e-31 109.5 4.1 7.1e-31 107.8 2.8 2.4 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66488.1 - 7.4e-27 94.5 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR66488.1 - 1.1e-12 47.5 0.0 2.6e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR66488.1 - 1.5e-09 37.8 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_23 PF13384.6 KIR66488.1 - 0.018 14.8 0.5 0.56 10.1 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Sigma54_DBD PF04552.13 KIR66488.1 - 0.09 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Peptidase_M17_N PF02789.17 KIR66488.1 - 0.099 12.5 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain MerR PF00376.23 KIR66488.1 - 0.1 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 MerR family regulatory protein TetR_N PF00440.23 KIR66488.1 - 0.4 10.5 2.0 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family SBP_bac_1 PF01547.25 KIR66489.1 - 7e-22 78.8 16.8 1.1e-21 78.1 16.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein RskA PF10099.9 KIR66489.1 - 0.26 11.6 6.1 0.72 10.1 0.4 2.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA BPD_transp_1 PF00528.22 KIR66490.1 - 1.4e-15 57.5 17.3 1.4e-15 57.5 17.3 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR66491.1 - 3.1e-18 66.2 16.7 3.1e-18 66.2 16.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3042 PF11240.8 KIR66492.1 - 0.66 10.0 0.0 0.66 10.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) PRA1 PF03208.19 KIR66492.1 - 1.8 8.2 6.8 0.66 9.6 2.8 2.2 1 1 1 2 2 2 0 PRA1 family protein Aldolase PF01081.19 KIR66493.1 - 4.2e-37 127.5 0.2 5.1e-37 127.2 0.2 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase TMP-TENI PF02581.17 KIR66493.1 - 9.2e-05 21.8 0.2 0.00053 19.4 0.0 2.2 2 1 1 3 3 3 1 Thiamine monophosphate synthase DHO_dh PF01180.21 KIR66493.1 - 0.032 13.5 0.3 0.44 9.7 0.1 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.14 KIR66493.1 - 0.12 11.5 0.3 0.84 8.8 0.0 2.4 3 1 1 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase Peripla_BP_3 PF13377.6 KIR66494.1 - 1e-36 126.8 4.1 1.1e-36 126.7 1.8 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66494.1 - 2.5e-28 99.3 0.0 3.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR66494.1 - 2.6e-17 62.4 0.2 1.2e-16 60.2 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR66494.1 - 1.7e-11 44.2 0.0 6.1e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR66494.1 - 0.00025 21.3 0.6 0.00025 21.3 0.6 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66494.1 - 0.0016 18.4 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_IclR PF09339.10 KIR66494.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain TetR_N PF00440.23 KIR66494.1 - 0.16 11.8 0.2 0.51 10.2 0.2 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 KIR66494.1 - 0.16 11.8 0.1 0.7 9.7 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain GFO_IDH_MocA PF01408.22 KIR66495.1 - 9.4e-09 36.1 0.0 1.6e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR66495.1 - 0.019 14.9 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KIR66495.1 - 0.064 13.9 0.1 0.1 13.3 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF993 PF06187.11 KIR66496.1 - 1.7e-176 586.8 3.5 2e-176 586.5 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF993) NAD_binding_11 PF14833.6 KIR66496.1 - 0.25 11.6 1.7 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase FUSC_2 PF13515.6 KIR66497.1 - 1e-14 54.7 14.8 1e-14 54.7 14.8 1.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC-like PF12805.7 KIR66497.1 - 0.0027 16.8 0.4 0.004 16.3 0.4 1.2 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS ArAE_1 PF06081.11 KIR66497.1 - 0.0047 17.1 8.6 0.0047 17.1 8.6 1.5 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 DUF2955 PF11168.8 KIR66497.1 - 0.17 11.7 10.0 0.29 11.0 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) YwiC PF14256.6 KIR66497.1 - 1.5 9.2 15.0 1.6 9.1 13.5 1.8 1 1 1 2 2 2 0 YwiC-like protein MFS_1 PF07690.16 KIR66498.1 - 2.2e-12 46.6 54.0 2.2e-12 46.6 54.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CPT PF07931.12 KIR66500.1 - 1.6e-55 187.6 0.1 1.8e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PBP_like PF12727.7 KIR66500.1 - 0.0094 15.1 1.6 0.093 11.8 0.7 2.3 1 1 1 2 2 2 1 PBP superfamily domain AAA_29 PF13555.6 KIR66500.1 - 0.15 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain CobN-Mg_chel PF02514.16 KIR66501.1 - 0 1362.7 0.0 0 1362.5 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase CobA_CobO_BtuR PF02572.15 KIR66502.1 - 3e-53 180.6 0.0 3.4e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP GATase_3 PF07685.14 KIR66503.1 - 9.9e-23 80.8 0.0 1.3e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 KIR66503.1 - 4.3e-19 68.8 0.0 3.5e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KIR66503.1 - 2.9e-12 46.8 0.6 1.8e-08 34.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain MobB PF03205.14 KIR66503.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 KIR66503.1 - 0.24 11.1 0.1 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiD PF01888.17 KIR66504.1 - 1.5e-87 293.1 4.9 1.8e-87 292.8 4.9 1.1 1 0 0 1 1 1 1 CbiD TP_methylase PF00590.20 KIR66505.1 - 3.3e-35 122.0 7.8 3.3e-35 122.0 7.8 2.7 3 0 0 3 3 3 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiG_C PF01890.16 KIR66505.1 - 2.1e-32 112.1 1.8 2.1e-32 112.1 1.8 2.6 2 1 0 2 2 2 1 Cobalamin synthesis G C-terminus CbiG_N PF11760.8 KIR66505.1 - 3.7e-31 107.0 4.1 3.7e-31 107.0 4.1 2.1 2 0 0 2 2 2 1 Cobalamin synthesis G N-terminal CbiG_mid PF11761.8 KIR66505.1 - 0.00011 22.3 0.1 0.00059 19.9 0.0 2.3 3 0 0 3 3 3 1 Cobalamin biosynthesis central region Fer4 PF00037.27 KIR66506.1 - 5.7e-12 44.9 13.0 2.7e-06 27.0 2.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KIR66506.1 - 2.9e-09 36.9 8.5 4e-09 36.5 8.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIR66506.1 - 4.4e-09 36.8 20.1 6.7e-07 29.8 10.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIR66506.1 - 2.5e-08 33.6 14.0 0.0002 21.3 2.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KIR66506.1 - 5.8e-08 32.7 12.5 3.5e-07 30.3 12.5 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIR66506.1 - 2.2e-07 31.7 13.0 0.00051 20.9 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KIR66506.1 - 2e-06 27.8 23.8 0.00031 20.8 13.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIR66506.1 - 3e-06 27.8 16.9 0.0074 17.2 3.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIR66506.1 - 1.6e-05 25.1 10.2 0.0087 16.5 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KIR66506.1 - 2e-05 24.9 7.2 0.029 14.8 0.9 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KIR66506.1 - 0.00051 20.0 16.3 0.026 14.6 2.0 2.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIR66506.1 - 0.0011 19.4 12.0 0.092 13.3 1.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_22 PF17179.4 KIR66506.1 - 0.0049 17.7 8.6 0.35 11.8 1.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIR66506.1 - 0.034 14.7 13.4 0.18 12.4 1.7 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KIR66506.1 - 0.76 10.0 10.8 4.2 7.6 2.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KIR66506.1 - 1.3 9.8 18.6 3.7 8.4 4.6 3.4 2 2 1 3 3 3 0 4Fe-4S single cluster domain CbiC PF02570.15 KIR66507.1 - 4.9e-59 199.3 0.2 5.6e-59 199.1 0.2 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase FAD_binding_3 PF01494.19 KIR66508.1 - 8.6e-22 77.9 0.2 2.2e-21 76.5 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR66508.1 - 1.2e-12 48.1 1.4 1.3e-06 28.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR66508.1 - 3e-08 33.2 2.2 0.00074 18.7 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIR66508.1 - 1e-06 28.4 1.6 3.2e-06 26.8 1.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR66508.1 - 0.00034 19.9 0.3 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KIR66508.1 - 0.00067 19.1 0.2 0.0018 17.7 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIR66508.1 - 0.00085 19.5 0.0 0.0031 17.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KIR66508.1 - 0.02 14.0 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 KIR66508.1 - 0.022 13.5 0.1 0.4 9.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KIR66508.1 - 0.043 14.4 0.1 12 6.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIR66508.1 - 0.12 11.2 3.3 3.5 6.4 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 KIR66508.1 - 0.24 10.4 0.1 0.47 9.5 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIR66508.1 - 0.25 10.5 0.0 0.5 9.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PepSY_TM PF03929.16 KIR66509.1 - 1.8e-63 214.9 18.3 2.6e-63 214.4 18.3 1.2 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 KIR66509.1 - 0.053 14.1 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain UbiA PF01040.18 KIR66509.1 - 0.083 12.2 29.6 0.069 12.4 10.3 3.2 3 0 0 3 3 3 0 UbiA prenyltransferase family CstA_5TM PF13722.6 KIR66509.1 - 1.8 9.0 6.1 0.47 10.8 0.2 2.8 3 0 0 3 3 3 0 5TM C-terminal transporter carbon starvation CstA CopC PF04234.12 KIR66510.1 - 6.7e-24 84.7 0.5 1.2e-23 84.0 0.5 1.4 1 0 0 1 1 1 1 CopC domain Big_5 PF13205.6 KIR66510.1 - 0.0029 18.3 1.9 0.0051 17.5 1.9 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain DUF202 PF02656.15 KIR66510.1 - 0.1 13.1 1.3 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Dyp_perox PF04261.12 KIR66511.1 - 1.4e-77 260.9 0.0 1.6e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family PCuAC PF04314.13 KIR66512.1 - 4.9e-33 113.2 0.5 6.7e-33 112.8 0.5 1.2 1 0 0 1 1 1 1 Copper chaperone PCu(A)C DUF4712 PF15830.5 KIR66512.1 - 0.28 10.8 0.2 0.36 10.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) CopC PF04234.12 KIR66513.1 - 1.3e-15 58.2 1.2 1.8e-14 54.5 0.0 3.3 2 1 1 3 3 3 1 CopC domain Pyr_redox_2 PF07992.14 KIR66514.1 - 1.4e-56 191.9 2.8 1.8e-56 191.6 2.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIR66514.1 - 3.9e-27 94.7 0.2 2.4e-25 88.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIR66514.1 - 3e-25 88.6 4.5 4.7e-20 71.9 0.2 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR66514.1 - 8.3e-11 41.7 1.2 2.7e-07 30.1 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIR66514.1 - 3e-09 36.8 0.2 3e-09 36.8 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIR66514.1 - 2.2e-08 34.2 1.8 0.0012 19.0 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIR66514.1 - 1.1e-07 31.4 2.1 0.00061 19.2 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KIR66514.1 - 4.7e-07 30.4 0.4 0.0041 17.6 0.1 2.4 2 0 0 2 2 2 2 XdhC Rossmann domain HI0933_like PF03486.14 KIR66514.1 - 5.3e-07 28.7 7.7 0.0041 15.9 0.3 3.2 2 1 1 3 3 3 3 HI0933-like protein 3HCDH_N PF02737.18 KIR66514.1 - 2.7e-06 27.4 2.5 6.2e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KIR66514.1 - 3.8e-06 26.3 7.1 0.012 14.8 1.1 3.6 3 0 0 3 3 3 3 FAD binding domain GIDA PF01134.22 KIR66514.1 - 5.4e-05 22.4 3.8 0.021 13.9 0.7 2.9 3 1 0 3 3 3 2 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KIR66514.1 - 0.00012 21.5 0.2 0.0043 16.4 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KIR66514.1 - 0.00033 20.3 8.7 0.051 13.2 0.1 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIR66514.1 - 0.00046 19.5 3.2 0.22 10.7 0.3 2.8 2 1 1 3 3 3 2 FAD binding domain Thi4 PF01946.17 KIR66514.1 - 0.00083 18.7 0.6 0.36 10.0 0.0 2.5 2 0 0 2 2 2 2 Thi4 family UDPG_MGDP_dh_N PF03721.14 KIR66514.1 - 0.0029 17.2 0.2 0.025 14.2 0.0 2.3 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 KIR66514.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KIR66514.1 - 0.012 16.0 0.5 0.098 13.1 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 KIR66514.1 - 0.014 15.7 0.7 0.057 13.7 0.1 2.3 2 1 0 2 2 2 0 TrkA-N domain Glu_dehyd_C PF16912.5 KIR66514.1 - 0.02 14.4 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 KIR66514.1 - 0.02 14.0 0.3 0.12 11.5 0.0 2.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 KIR66514.1 - 0.046 13.4 0.7 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KIR66514.1 - 0.11 12.6 0.1 0.33 11.0 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KIR66514.1 - 3.1 6.8 7.1 10 5.1 0.1 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein DUF1304 PF06993.12 KIR66515.1 - 5.5e-33 113.2 8.1 8e-33 112.7 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) DUF4173 PF13777.6 KIR66515.1 - 0.0073 15.7 3.0 0.0074 15.7 2.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4173) ThrE_2 PF12821.7 KIR66516.1 - 0.0085 16.2 1.9 0.011 15.9 1.9 1.1 1 0 0 1 1 1 1 Threonine/Serine exporter, ThrE HlyIII PF03006.20 KIR66516.1 - 0.059 13.1 0.1 0.071 12.8 0.1 1.0 1 0 0 1 1 1 0 Haemolysin-III related DUF4131 PF13567.6 KIR66516.1 - 0.18 11.5 4.5 0.27 10.9 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CBM_2 PF00553.19 KIR66518.1 - 8.2e-28 96.7 15.6 8.2e-28 96.7 15.6 2.9 2 0 0 2 2 2 1 Cellulose binding domain ROK PF00480.20 KIR66519.1 - 1.5e-42 146.1 0.0 2.1e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 KIR66519.1 - 2.6e-05 24.0 1.2 6.7e-05 22.7 1.2 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KIR66519.1 - 0.0039 17.1 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR66519.1 - 0.0068 16.9 0.0 0.02 15.4 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 KIR66519.1 - 0.025 14.5 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 KIR66519.1 - 0.18 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_20 PF12840.7 KIR66519.1 - 0.36 10.9 3.2 0.29 11.2 0.7 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Cupin_2 PF07883.11 KIR66520.1 - 1.2e-10 40.9 2.4 2.4e-10 40.0 1.3 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KIR66520.1 - 9.4e-05 22.1 0.2 0.00014 21.5 0.2 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 KIR66520.1 - 0.0052 17.0 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family Cupin_8 PF13621.6 KIR66520.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain AraC_binding PF02311.19 KIR66520.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain LysR_substrate PF03466.20 KIR66521.1 - 6.8e-22 77.9 10.0 1e-21 77.3 10.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 KIR66521.1 - 1.5e-19 69.7 0.3 3.4e-19 68.5 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 KIR66521.1 - 0.019 14.8 0.3 0.21 11.5 0.2 2.8 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 KIR66521.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_30 PF13556.6 KIR66521.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 KIR66521.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family BPD_transp_1 PF00528.22 KIR66522.1 - 1.4e-13 51.0 16.4 1.4e-13 51.0 16.4 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KIR66522.1 - 0.00074 19.4 1.2 0.00074 19.4 1.2 3.0 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C Pmp3 PF01679.17 KIR66522.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.6 2 1 0 2 2 2 0 Proteolipid membrane potential modulator ABC_tran PF00005.27 KIR66523.1 - 2.4e-31 109.1 0.0 3.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR66523.1 - 2.6e-07 31.0 0.0 4.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR66523.1 - 1.8e-06 28.0 1.0 0.0023 17.8 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR66523.1 - 1.2e-05 25.7 7.5 2.6e-05 24.7 7.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIR66523.1 - 1.7e-05 24.4 0.1 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR66523.1 - 0.0011 19.2 1.2 0.024 14.9 1.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR66523.1 - 0.0013 18.5 0.1 0.0028 17.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KIR66523.1 - 0.0036 17.5 0.1 0.044 14.0 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 KIR66523.1 - 0.0054 15.8 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIR66523.1 - 0.0062 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 KIR66523.1 - 0.026 14.6 0.5 0.046 13.8 0.5 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KIR66523.1 - 0.033 14.3 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 KIR66523.1 - 0.042 12.7 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 KIR66523.1 - 0.059 13.1 5.4 0.79 9.4 5.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR66523.1 - 0.092 12.9 0.4 0.24 11.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIR66523.1 - 0.13 12.7 0.0 0.87 10.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIR66523.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KIR66523.1 - 0.22 11.4 2.4 0.28 11.1 0.1 2.1 2 1 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KIR66523.1 - 0.31 11.5 0.1 0.47 10.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 KIR66524.1 - 9.3e-62 209.3 0.9 1.2e-61 208.9 0.9 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIR66524.1 - 2.4e-06 26.9 14.9 0.007 15.5 6.7 2.5 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 KIR66524.1 - 3.6e-06 26.8 3.9 3.6e-06 26.8 3.9 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR66524.1 - 0.00015 21.1 1.3 0.0038 16.5 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIR66524.1 - 0.00029 21.0 0.7 0.001 19.3 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIR66524.1 - 0.00029 19.7 1.4 0.016 13.9 3.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KIR66524.1 - 0.0031 16.8 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIR66524.1 - 0.0072 15.6 0.6 0.012 14.9 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR66524.1 - 0.0096 16.5 2.7 0.15 12.6 1.8 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIR66524.1 - 0.027 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIR66524.1 - 0.033 13.8 0.5 0.059 12.9 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIR66524.1 - 0.037 13.9 1.4 0.1 12.5 1.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KIR66524.1 - 0.05 12.9 7.0 0.34 10.2 7.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KIR66524.1 - 0.088 11.9 3.1 0.12 11.4 3.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Hydrolase_4 PF12146.8 KIR66525.1 - 1.5e-08 34.2 0.3 0.0078 15.5 0.1 2.9 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIR66525.1 - 0.051 13.7 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Flavin_Reduct PF01613.18 KIR66526.1 - 8.7e-39 133.0 0.2 1e-38 132.8 0.2 1.0 1 0 0 1 1 1 1 Flavin reductase like domain GSDH PF07995.11 KIR66527.1 - 7.7e-73 245.7 0.1 1.1e-72 245.1 0.1 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase CBM_2 PF00553.19 KIR66527.1 - 4.8e-30 103.8 8.1 1.1e-29 102.8 8.1 1.6 1 0 0 1 1 1 1 Cellulose binding domain Reg_prop PF07494.11 KIR66527.1 - 0.0056 16.8 0.4 3.3 8.3 0.1 3.3 3 0 0 3 3 3 2 Two component regulator propeller PQQ_3 PF13570.6 KIR66527.1 - 5.5 7.6 19.0 18 5.9 0.1 5.9 4 1 2 6 6 6 0 PQQ-like domain Phage_holin_2_4 PF16082.5 KIR66528.1 - 0.36 10.6 3.1 0.32 10.8 0.9 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Peptidase_M48 PF01435.18 KIR66529.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M48 CBM_2 PF00553.19 KIR66530.1 - 5e-30 103.8 10.2 5e-30 103.8 10.2 1.7 2 0 0 2 2 2 1 Cellulose binding domain Lipase_GDSL_2 PF13472.6 KIR66530.1 - 5.2e-17 62.8 2.2 5.2e-17 62.8 2.2 2.6 2 1 1 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR66530.1 - 6.1e-10 39.4 0.8 4.1e-09 36.7 0.0 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KIR66530.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AbfB PF05270.13 KIR66531.1 - 8.6e-47 158.6 0.4 2.2e-46 157.3 0.4 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Glyco_hydro_43 PF04616.14 KIR66531.1 - 1.1e-06 28.1 0.7 2.9e-06 26.8 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KIR66531.1 - 0.012 15.2 0.3 0.044 13.4 0.3 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DUF1275 PF06912.11 KIR66531.1 - 2.6 7.9 4.7 22 4.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KIR66532.1 - 1e-54 185.9 42.7 1e-54 185.9 42.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR66532.1 - 2.4e-05 23.4 12.4 2.4e-05 23.4 12.4 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIR66532.1 - 5.7e-05 21.7 11.6 5.7e-05 21.7 11.6 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIR66532.1 - 0.0039 16.1 8.7 0.0039 16.1 8.7 2.3 2 0 0 2 2 2 1 MFS_1 like family Glyco_hydro_67M PF07488.12 KIR66534.1 - 1.1e-133 445.3 0.0 1.6e-133 444.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KIR66534.1 - 2.4e-91 305.2 0.0 3.3e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KIR66534.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF3526 PF12040.8 KIR66534.1 - 0.082 13.4 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) DUF624 PF04854.14 KIR66535.1 - 0.0013 18.8 2.3 0.0018 18.3 0.0 2.4 2 2 0 2 2 2 1 Protein of unknown function, DUF624 SBP_bac_8 PF13416.6 KIR66536.1 - 2.4e-21 76.8 2.9 3.7e-21 76.2 2.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR66536.1 - 3.1e-14 53.6 6.7 6.2e-14 52.7 6.7 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF2713 PF10897.8 KIR66536.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) BPD_transp_1 PF00528.22 KIR66537.1 - 1.4e-18 67.3 7.3 1.4e-18 67.3 7.3 1.9 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component Glyco_hydro_3 PF00933.21 KIR66538.1 - 6.4e-67 226.2 0.0 9.2e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KIR66538.1 - 1.7e-52 178.4 0.0 2.8e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KIR66538.1 - 1.7e-19 69.7 0.3 3.3e-19 68.8 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 KIR66538.1 - 0.017 15.4 0.8 0.017 15.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF11 CARDB PF07705.11 KIR66538.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 CARDB AXE1 PF05448.12 KIR66539.1 - 1.2e-95 319.9 0.0 1.4e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KIR66539.1 - 5.5e-06 26.0 0.0 9.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIR66539.1 - 1.5e-05 25.0 1.6 3.2e-05 23.9 0.3 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR66539.1 - 0.005 16.1 0.8 0.039 13.2 0.7 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIR66539.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KIR66539.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family MR_MLE_C PF13378.6 KIR66540.1 - 8.2e-45 153.0 0.5 1.2e-44 152.5 0.5 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIR66540.1 - 2.2e-31 108.5 0.0 4.2e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SWIM PF04434.17 KIR66541.1 - 1.2e-05 24.8 0.4 2.7e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger DprA_WH PF17782.1 KIR66541.1 - 0.00036 20.6 3.1 0.0013 18.8 3.1 1.9 1 0 0 1 1 1 1 DprA winged helix domain DUF2300 PF10062.9 KIR66542.1 - 0.096 12.8 2.0 0.37 10.9 0.1 2.7 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) IclR PF01614.18 KIR66543.1 - 7.9e-23 80.7 0.0 1.5e-22 79.8 0.0 1.4 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR66543.1 - 4.4e-16 58.4 0.6 1e-15 57.2 0.6 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 KIR66543.1 - 0.00056 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KIR66543.1 - 0.0035 17.2 3.8 0.0073 16.2 0.4 2.9 2 1 1 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 KIR66543.1 - 0.0038 17.2 0.1 0.015 15.2 0.0 2.0 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 KIR66543.1 - 0.0062 16.5 0.3 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_20 PF12840.7 KIR66543.1 - 0.0069 16.4 2.2 0.035 14.2 0.1 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain TrmB PF01978.19 KIR66543.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.6 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 KIR66543.1 - 0.041 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 KIR66543.1 - 0.042 13.5 0.8 0.15 11.7 0.1 2.3 2 1 1 3 3 3 0 Bacterial regulatory proteins, gntR family PI-TkoII_IV PF18714.1 KIR66543.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Rrf2 PF02082.20 KIR66543.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 KIR66543.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 KIR66543.1 - 0.11 12.4 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain SAVED PF18145.1 KIR66543.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain Citrate_synt PF00285.21 KIR66544.1 - 2.8e-21 76.0 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain LigB PF02900.18 KIR66545.1 - 1.8e-25 89.5 0.0 2.1e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LigA PF07746.11 KIR66546.1 - 0.0017 18.4 0.0 0.65 10.2 0.0 2.2 1 1 1 2 2 2 2 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Potass_KdpF PF09604.10 KIR66547.1 - 6.2e-08 32.4 7.5 6.9e-08 32.3 7.5 1.1 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) KdpA PF03814.15 KIR66548.1 - 7.8e-228 757.1 31.9 9.2e-228 756.9 31.9 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit E1-E2_ATPase PF00122.20 KIR66549.1 - 1e-30 106.6 2.5 1e-30 106.6 2.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KIR66549.1 - 3.7e-30 105.8 2.1 6.4e-30 105.0 2.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIR66549.1 - 3.4e-05 24.3 0.4 0.0034 17.8 0.0 3.0 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIR66549.1 - 0.0003 20.6 0.7 0.0017 18.1 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase KdpC PF02669.15 KIR66550.1 - 8.1e-56 188.7 0.1 5.8e-32 111.0 0.0 2.1 2 0 0 2 2 2 2 K+-transporting ATPase, c chain Response_reg PF00072.24 KIR66551.1 - 1.9e-28 98.9 0.0 2.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR66551.1 - 5.7e-22 77.6 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 KIR66551.1 - 0.029 14.3 0.0 0.088 12.7 0.0 2.0 1 0 0 1 1 1 0 MarR family YccF PF03733.13 KIR66552.1 - 1.5e-34 118.5 29.4 1e-18 67.7 11.0 2.0 2 0 0 2 2 2 2 Inner membrane component domain DUF3930 PF13067.6 KIR66552.1 - 7.6 6.9 7.7 7 7.0 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) Ribosomal_S4 PF00163.19 KIR66553.1 - 2.7e-21 76.3 0.7 4.9e-21 75.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KIR66553.1 - 1.9e-16 59.5 0.0 6.2e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KIR66553.1 - 0.0037 17.1 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 S4 domain Abhydrolase_6 PF12697.7 KIR66554.1 - 1.6e-23 84.5 15.1 1.8e-23 84.3 15.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIR66554.1 - 9.6e-18 64.7 0.1 3.3e-17 63.0 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIR66554.1 - 1.3e-12 47.6 0.1 1.8e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KIR66554.1 - 0.00073 18.7 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 KIR66554.1 - 0.00095 18.9 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KIR66554.1 - 0.0037 16.0 0.0 0.011 14.4 0.0 1.8 1 1 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KIR66554.1 - 0.0039 16.7 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KIR66554.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KIR66554.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KIR66554.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 KIR66554.1 - 0.025 13.1 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 KIR66554.1 - 0.025 14.4 0.2 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KIR66554.1 - 0.029 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KIR66554.1 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Ser_hydrolase PF06821.13 KIR66554.1 - 0.13 12.1 0.2 0.31 10.9 0.2 1.8 1 1 0 1 1 1 0 Serine hydrolase AXE1 PF05448.12 KIR66554.1 - 0.17 10.5 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Polyketide_cyc2 PF10604.9 KIR66555.1 - 3e-07 30.8 0.3 3e-07 30.8 0.3 2.5 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KIR66555.1 - 4e-07 30.3 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein CBM_2 PF00553.19 KIR66555.1 - 2.1e-06 27.9 0.0 3.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Cellulose binding domain DUF2505 PF10698.9 KIR66555.1 - 0.037 14.1 0.0 0.13 12.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2505) FAP PF07174.11 KIR66555.1 - 0.06 12.8 15.8 0.097 12.1 15.8 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Glyco_hydro_16 PF00722.21 KIR66556.1 - 2.1e-42 144.6 0.1 3e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ricin_B_lectin PF00652.22 KIR66556.1 - 1.6e-26 93.1 7.2 1.8e-26 92.8 3.4 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66556.1 - 3.5e-24 85.3 13.3 4.2e-11 43.4 0.4 3.8 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like SKN1 PF03935.15 KIR66556.1 - 1.2e-10 40.4 1.4 1.5e-06 26.9 0.0 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Peptidase_S8 PF00082.22 KIR66557.1 - 2.3e-22 79.6 15.9 5.5e-22 78.4 15.9 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIR66557.1 - 0.00032 21.3 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 HTH_32 PF13565.6 KIR66557.1 - 0.17 12.5 0.1 2.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_S8 PF00082.22 KIR66558.1 - 2.2e-35 122.4 22.8 4.8e-35 121.3 22.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIR66558.1 - 5e-09 36.7 0.0 8.6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 PfkB PF00294.24 KIR66559.1 - 1e-54 185.9 3.4 1.1e-54 185.8 3.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIR66559.1 - 7.9e-08 32.0 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 KIR66559.1 - 0.0001 21.9 0.1 0.00023 20.7 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate kinase BPD_transp_2 PF02653.16 KIR66560.1 - 2.8e-44 151.3 47.6 2.8e-44 151.3 47.6 1.6 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component Peripla_BP_4 PF13407.6 KIR66561.1 - 2e-47 162.0 2.8 3e-47 161.4 2.8 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KIR66561.1 - 3.8e-07 29.8 0.1 5.4e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 KIR66561.1 - 3e-05 24.4 0.0 0.0036 17.6 0.0 3.0 1 1 1 2 2 2 1 Periplasmic binding protein-like domain RbsD_FucU PF05025.13 KIR66562.1 - 9.9e-34 116.7 0.0 1.1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family FAD_binding_3 PF01494.19 KIR66563.1 - 2.2e-19 69.9 0.1 3.8e-19 69.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIR66563.1 - 1.4e-07 31.5 2.5 0.0021 17.7 1.2 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIR66563.1 - 7e-06 25.4 0.5 0.019 14.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KIR66563.1 - 2.7e-05 23.7 0.2 7.8e-05 22.2 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KIR66563.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KIR66563.1 - 0.0076 15.5 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR66563.1 - 0.0091 15.1 0.1 0.018 14.1 0.1 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KIR66563.1 - 0.02 14.2 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KIR66563.1 - 0.022 13.6 0.4 1 8.1 0.2 2.1 1 1 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KIR66563.1 - 0.03 13.0 0.0 0.66 8.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 KIR66563.1 - 0.05 13.0 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_8 PF13450.6 KIR66563.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KIR66563.1 - 0.056 13.3 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIR66563.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_alkylation PF08713.11 KIR66564.1 - 3.5e-06 26.9 0.1 5.2e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 DNA alkylation repair enzyme HEAT_2 PF13646.6 KIR66564.1 - 0.00028 21.2 2.8 0.1 13.0 0.1 3.3 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 KIR66564.1 - 0.00039 20.4 0.1 0.047 14.0 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat Cupredoxin_1 PF13473.6 KIR66564.1 - 0.21 11.7 0.0 0.82 9.8 0.0 1.8 2 1 0 2 2 2 0 Cupredoxin-like domain Aminotran_1_2 PF00155.21 KIR66565.1 - 2.1e-51 175.2 0.0 2.9e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PS-DH PF14765.6 KIR66565.1 - 1.5e-42 145.9 0.3 2.5e-42 145.2 0.3 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KIR66565.1 - 4.9e-40 137.4 0.0 8.6e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 KIR66565.1 - 5.1e-14 52.4 0.1 1.3e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KIR66565.1 - 8.8e-10 38.4 0.0 2.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Cys_Met_Meta_PP PF01053.20 KIR66565.1 - 2.2e-07 29.7 0.0 4.6e-07 28.7 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIR66565.1 - 2.1e-05 23.7 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIR66565.1 - 9.5e-05 21.9 0.7 0.00029 20.3 0.7 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Epimerase PF01370.21 KIR66565.1 - 0.00036 20.1 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta_elim_lyase PF01212.21 KIR66565.1 - 0.0057 16.0 0.1 0.0098 15.2 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 KIR66565.1 - 0.051 12.2 0.0 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III OKR_DC_1 PF01276.20 KIR66565.1 - 0.071 11.8 0.0 0.51 9.0 0.0 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 2-Hacid_dh_C PF02826.19 KIR66565.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SepSecS PF05889.13 KIR66565.1 - 0.17 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDP_Man_Dehyd PF16363.5 KIR66565.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ThiF PF00899.21 KIR66565.1 - 0.23 10.8 4.7 0.53 9.6 4.7 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_10 PF13460.6 KIR66565.1 - 2.2 8.1 4.4 0.45 10.4 0.2 2.1 3 0 0 3 3 1 0 NAD(P)H-binding DnaB_2 PF07261.11 KIR66566.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment DnaB_bind PF10410.9 KIR66566.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Hist_deacetyl PF00850.19 KIR66567.1 - 8.5e-75 252.1 1.1 1.5e-74 251.2 1.1 1.3 1 1 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.16 KIR66568.1 - 7.3e-43 146.8 49.8 7.4e-43 146.8 46.0 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR66568.1 - 0.00042 19.3 9.8 0.00042 19.3 9.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIR66568.1 - 0.00075 18.5 17.7 0.0067 15.3 7.1 2.3 2 0 0 2 2 2 2 MFS_1 like family TMEM117 PF15113.6 KIR66568.1 - 0.067 12.1 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 TMEM117 protein family OATP PF03137.20 KIR66568.1 - 0.77 8.0 16.0 8.9 4.5 9.8 3.2 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_32N PF00251.20 KIR66569.1 - 5.9e-17 62.2 0.0 7.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KIR66569.1 - 9e-08 31.8 0.1 5.5e-07 29.2 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 KIR66569.1 - 4e-07 29.3 1.3 5.5e-07 28.8 1.3 1.1 1 0 0 1 1 1 1 Levansucrase/Invertase BNR_4 PF15892.5 KIR66569.1 - 0.32 10.3 2.1 8.9 5.6 0.2 2.2 2 0 0 2 2 2 0 BNR repeat-containing family member Peripla_BP_3 PF13377.6 KIR66570.1 - 1.9e-29 103.1 7.1 6.2e-29 101.5 0.8 2.6 2 1 1 3 3 3 2 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66570.1 - 9.8e-27 94.1 0.0 1.9e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR66570.1 - 1.5e-15 57.5 0.0 2.9e-15 56.6 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 KIR66570.1 - 1.5e-14 53.5 0.0 2.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 KIR66570.1 - 0.016 15.5 1.4 0.055 13.8 1.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain SBP_bac_1 PF01547.25 KIR66571.1 - 4.8e-23 82.6 13.2 4.8e-23 82.6 13.2 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 KIR66572.1 - 8.8e-13 48.4 14.4 8.8e-13 48.4 14.4 2.3 1 1 2 3 3 3 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KIR66573.1 - 3.7e-17 62.7 14.3 3.7e-17 62.7 14.3 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Beta-lactamase PF00144.24 KIR66574.1 - 1.3e-71 241.5 9.3 1.6e-71 241.3 9.3 1.0 1 0 0 1 1 1 1 Beta-lactamase PT PF04886.12 KIR66576.1 - 0.0073 15.8 0.2 0.0073 15.8 0.2 2.5 3 0 0 3 3 3 1 PT repeat HlyD_D23 PF16576.5 KIR66577.1 - 1.5e-16 60.3 1.0 3e-15 56.0 1.0 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KIR66577.1 - 3.8e-16 59.7 4.6 6.5e-11 42.9 0.4 2.8 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KIR66577.1 - 6.5e-05 22.7 5.2 0.0069 16.2 0.4 3.0 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 KIR66577.1 - 0.00026 20.8 0.1 1 9.2 0.0 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme RnfC_N PF13375.6 KIR66577.1 - 0.00051 19.9 1.3 0.11 12.5 0.2 2.6 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 KIR66577.1 - 0.00052 20.2 0.4 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M23 TarH PF02203.15 KIR66577.1 - 0.05 13.5 3.2 1.1 9.1 0.3 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue PilZ PF07238.14 KIR66577.1 - 0.14 12.5 0.0 0.43 10.9 0.0 1.8 1 1 1 2 2 2 0 PilZ domain DUF4588 PF15251.6 KIR66577.1 - 0.19 11.5 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) OEP PF02321.18 KIR66577.1 - 0.57 10.0 5.5 1.4 8.7 0.3 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein DUF4398 PF14346.6 KIR66577.1 - 7.1 7.3 25.1 0.22 12.2 10.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) MacB_PCD PF12704.7 KIR66578.1 - 2e-36 126.2 13.4 2e-36 126.2 13.4 3.3 3 1 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 KIR66578.1 - 1.9e-09 37.9 14.5 2.5e-08 34.3 4.3 3.5 3 1 0 3 3 3 2 FtsX-like permease family ABC2_membrane_3 PF12698.7 KIR66578.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Na_H_Exchanger PF00999.21 KIR66579.1 - 2e-56 191.5 41.7 2.5e-56 191.1 41.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PP_kinase PF02503.17 KIR66579.1 - 0.13 11.8 1.0 0.2 11.2 1.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase middle domain ParA PF10609.9 KIR66582.1 - 0.0022 17.5 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIR66582.1 - 0.0047 17.0 0.0 0.009 16.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KIR66582.1 - 0.029 13.7 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 ATPase MipZ AAA_31 PF13614.6 KIR66582.1 - 0.23 11.3 0.0 18 5.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4148 PF13663.6 KIR66583.1 - 4.2 7.6 5.2 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Peptidase_M19 PF01244.21 KIR66584.1 - 3.2e-61 207.3 0.0 6.4e-61 206.3 0.0 1.4 1 1 1 2 2 2 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 KIR66584.1 - 0.00058 19.7 0.1 0.00079 19.3 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase SBP_bac_5 PF00496.22 KIR66585.1 - 7.4e-68 229.2 7.3 9.8e-68 228.8 7.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_3 PF00497.20 KIR66585.1 - 0.014 14.9 3.4 2.7 7.3 0.0 2.8 3 1 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 KIR66586.1 - 5.1e-40 137.2 6.8 5.1e-40 137.2 6.8 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SKG6 PF08693.10 KIR66586.1 - 1.6 8.2 5.1 0.63 9.5 0.5 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BPD_transp_1 PF00528.22 KIR66587.1 - 1.1e-19 70.9 19.8 1.1e-19 70.9 19.8 1.9 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KIR66587.1 - 2.1e-09 37.2 0.1 2.1e-09 37.2 0.1 4.8 4 1 1 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C GspL_C PF12693.7 KIR66587.1 - 8.4 6.2 6.8 1.7 8.5 0.4 2.4 2 0 0 2 2 2 0 GspL periplasmic domain Abhydrolase_1 PF00561.20 KIR66588.1 - 6.6e-29 101.3 0.0 3.8e-26 92.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR66588.1 - 4.6e-16 60.1 5.3 5.6e-16 59.8 5.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR66588.1 - 2.1e-15 56.6 0.1 1.3e-14 54.0 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KIR66588.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KIR66588.1 - 1.6e-06 27.7 0.0 0.0068 15.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 KIR66588.1 - 4.7e-05 23.6 0.0 5.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 KIR66588.1 - 0.00037 20.6 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 KIR66588.1 - 0.00049 20.0 1.4 0.028 14.3 0.8 2.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIR66588.1 - 0.0067 16.2 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KIR66588.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 KIR66588.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 KIR66588.1 - 0.098 11.3 0.0 0.31 9.7 0.0 1.7 2 0 0 2 2 2 0 Ndr family Bep_C_terminal PF17841.1 KIR66588.1 - 0.15 12.3 0.3 3.4 8.0 0.0 2.2 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) tRNA-synt_1d PF00750.19 KIR66589.1 - 5.8e-102 341.2 0.0 7.4e-102 340.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KIR66589.1 - 5.7e-30 103.9 0.0 1.2e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KIR66589.1 - 7e-14 52.2 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 KIR66589.1 - 0.0018 17.1 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIR66589.1 - 0.084 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) HTH_32 PF13565.6 KIR66589.1 - 0.13 12.8 0.6 35 5.1 0.0 3.4 3 0 0 3 3 3 0 Homeodomain-like domain tRNA-synt_1e PF01406.19 KIR66589.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TetR_C_14 PF17754.1 KIR66589.1 - 1.7 8.6 10.8 0.2 11.6 1.4 3.4 3 1 0 3 3 3 0 MftR C-terminal domain PAAR_motif PF05488.13 KIR66590.1 - 5.5e-12 45.7 9.8 2.8e-11 43.4 3.2 2.1 1 1 1 2 2 2 2 PAAR motif DZR PF12773.7 KIR66591.1 - 0.00017 21.6 0.1 0.00028 20.8 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KIR66591.1 - 0.0013 18.3 4.5 0.002 17.8 4.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIR66591.1 - 0.0019 17.5 3.9 0.0033 16.8 3.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain F5_F8_type_C PF00754.25 KIR66591.1 - 0.0065 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain zf-RanBP PF00641.18 KIR66591.1 - 0.016 14.5 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Mu-transpos_C PF09299.11 KIR66591.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Mu transposase, C-terminal Nudix_N_2 PF14803.6 KIR66591.1 - 0.46 10.4 5.4 2.5 8.1 0.3 2.6 2 0 0 2 2 2 0 Nudix N-terminal ketoacyl-synt PF00109.26 KIR66592.1 - 2.7e-71 240.1 0.6 4.6e-71 239.3 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KIR66592.1 - 5.1e-39 132.9 0.6 9.8e-39 132.0 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KIR66592.1 - 2.2e-08 34.5 0.0 3.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KIR66592.1 - 7e-06 25.6 0.4 1.5e-05 24.5 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KIR66593.1 - 5.5e-61 206.1 0.0 6.3e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIR66593.1 - 3.4e-12 46.2 0.0 5.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66593.1 - 0.006 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Enoyl_reductase PF12241.8 KIR66593.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Glyco_transf_4 PF13439.6 KIR66593.1 - 0.11 12.5 0.4 14 5.6 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 PaaA_PaaC PF05138.12 KIR66594.1 - 1.5e-19 70.2 0.0 1.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Phenylacetic acid catabolic protein MiaE_2 PF13794.6 KIR66594.1 - 0.00047 19.9 0.0 0.00057 19.6 0.0 1.1 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF455 PF04305.14 KIR66594.1 - 0.064 12.8 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF455) RicinB_lectin_2 PF14200.6 KIR66595.1 - 9.8e-34 116.0 22.1 4e-15 56.3 2.1 4.2 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66595.1 - 3e-32 111.5 7.0 8.2e-32 110.1 7.0 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Esterase_phd PF10503.9 KIR66595.1 - 7.6e-21 74.6 1.7 7.9e-21 74.6 0.3 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIR66595.1 - 1e-10 41.5 0.9 2.3e-10 40.3 0.9 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIR66595.1 - 0.00049 19.8 0.3 0.00086 19.0 0.3 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 KIR66595.1 - 0.0018 17.8 0.9 0.0038 16.8 0.2 1.9 1 1 1 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KIR66595.1 - 0.0019 18.0 0.2 0.0089 15.8 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 KIR66595.1 - 0.027 14.3 0.1 0.056 13.3 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KIR66595.1 - 0.045 13.7 0.0 0.085 12.8 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LPMO_10 PF03067.15 KIR66597.1 - 4.8e-27 95.9 4.5 5.4e-27 95.7 4.5 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading SnoaL_2 PF12680.7 KIR66598.1 - 6.7e-17 62.0 0.3 8e-17 61.8 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain PHZA_PHZB PF03284.13 KIR66598.1 - 2.4e-08 33.7 0.0 3e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B DUF4440 PF14534.6 KIR66598.1 - 8.8e-05 22.9 0.1 0.00012 22.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 KIR66598.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 KIR66598.1 - 0.00018 21.7 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 KIR66598.1 - 0.013 15.6 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain NTF2 PF02136.20 KIR66598.1 - 0.058 14.0 0.0 0.064 13.8 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain WI12 PF07107.11 KIR66598.1 - 0.11 12.6 0.1 0.18 11.9 0.0 1.3 1 1 0 1 1 1 0 Wound-induced protein WI12 RicinB_lectin_2 PF14200.6 KIR66599.1 - 7.1e-37 126.0 8.8 7.2e-24 84.3 1.7 2.8 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66599.1 - 6.1e-20 71.8 4.7 1.3e-19 70.7 4.6 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Cellulase PF00150.18 KIR66599.1 - 1.1e-18 67.6 3.6 2.6e-18 66.4 3.6 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chlorophyllase2 PF12740.7 KIR66601.1 - 0.065 12.1 0.5 2.5 6.9 0.0 3.0 3 1 0 3 3 3 0 Chlorophyllase enzyme FhuF PF06276.12 KIR66604.1 - 1.1e-09 38.9 1.3 1.6e-09 38.4 1.3 1.2 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter FhuF_C PF11575.8 KIR66604.1 - 0.074 13.0 9.4 0.15 12.0 9.4 1.6 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain HisKA PF00512.25 KIR66605.1 - 2.1e-16 59.7 1.1 5.8e-16 58.3 1.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR66605.1 - 7.3e-12 45.5 3.4 7.3e-12 45.5 3.4 3.2 3 0 0 3 3 3 1 HAMP domain HATPase_c PF02518.26 KIR66605.1 - 2e-11 44.4 0.0 3.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glycos_transf_2 PF00535.26 KIR66607.1 - 8.9e-23 80.9 0.0 1.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66607.1 - 1.2e-16 61.3 0.1 2.4e-16 60.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR66607.1 - 3.1e-10 40.0 0.0 0.00047 19.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 TPR_14 PF13428.6 KIR66607.1 - 0.003 18.3 1.4 0.003 18.3 1.4 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Sulfotransfer_3 PF13469.6 KIR66608.1 - 2.9e-17 63.8 0.9 1.4e-16 61.5 0.9 2.0 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR66608.1 - 8.8e-12 45.1 0.0 6.8e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain NADH-G_4Fe-4S_3 PF10588.9 KIR66608.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Sulfotransfer_3 PF13469.6 KIR66609.1 - 2.5e-13 50.9 0.0 3.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KIR66609.1 - 2.6e-06 27.1 0.0 1.2e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain MatE PF01554.18 KIR66611.1 - 3.2e-20 72.4 17.0 2e-12 47.1 4.8 2.9 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KIR66611.1 - 6.7e-19 68.4 15.1 6.7e-19 68.4 15.1 3.5 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 KIR66611.1 - 6.7e-08 32.1 0.1 6.7e-08 32.1 0.1 3.1 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein MurJ PF03023.14 KIR66611.1 - 7.4e-07 28.1 10.2 7.4e-07 28.1 10.2 1.9 2 0 0 2 2 2 1 Lipid II flippase MurJ Polysacc_synt PF01943.17 KIR66611.1 - 9.8e-07 28.4 5.4 9.8e-07 28.4 5.4 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein YrvL PF14184.6 KIR66611.1 - 0.56 10.3 2.8 1.2 9.3 2.8 1.5 1 0 0 1 1 1 0 Regulatory protein YrvL Glyco_hydro_26 PF02156.15 KIR66612.1 - 0.00057 19.4 0.1 0.00077 19.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Pectate_lyase PF03211.13 KIR66613.1 - 2.4e-81 272.1 3.9 3e-81 271.8 3.9 1.1 1 0 0 1 1 1 1 Pectate lyase DUF4805 PF16063.5 KIR66613.1 - 0.22 10.8 0.6 0.35 10.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) CBM_2 PF00553.19 KIR66614.1 - 2.7e-31 107.9 7.6 2.7e-31 107.9 7.6 2.5 2 0 0 2 2 2 1 Cellulose binding domain Glyco_hydro_30C PF17189.4 KIR66614.1 - 7.5e-07 29.3 4.8 8.6e-07 29.1 2.7 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 KIR66614.1 - 0.029 13.4 0.3 0.065 12.2 0.3 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydr_30_2 PF14587.6 KIR66614.1 - 0.1 12.2 3.0 0.14 11.8 0.3 2.3 2 1 1 3 3 3 0 O-Glycosyl hydrolase family 30 Alpha-amylase_C PF02806.18 KIR66614.1 - 0.13 12.7 0.1 0.35 11.4 0.1 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain HATPase_c PF02518.26 KIR66615.1 - 1.9e-25 89.6 0.0 5.3e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR66615.1 - 1.5e-17 63.4 3.1 8.4e-17 61.0 1.3 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR66615.1 - 4.3e-15 55.8 2.8 5.3e-15 55.5 0.6 2.3 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 KIR66615.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain LytR_cpsA_psr PF03816.14 KIR66617.1 - 1.3e-40 139.1 0.0 2.1e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Rhodanese PF00581.20 KIR66618.1 - 1.9e-15 57.3 0.0 2.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4224 PF13986.6 KIR66618.1 - 0.069 13.1 0.3 0.31 11.0 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4224) HATPase_c PF02518.26 KIR66619.1 - 3.5e-20 72.6 0.0 7.8e-20 71.5 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR66619.1 - 9.2e-12 44.8 0.1 2e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KIR66619.1 - 2.6e-07 30.8 0.0 0.0034 17.5 0.0 2.8 1 1 1 2 2 2 2 PAS fold PAS_8 PF13188.7 KIR66619.1 - 9.3e-07 28.7 0.0 2.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KIR66619.1 - 3.6e-06 26.9 0.0 8.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KIR66619.1 - 6.7e-06 26.3 0.7 2.2e-05 24.6 0.0 2.3 3 0 0 3 3 3 1 PAS fold HATPase_c_2 PF13581.6 KIR66619.1 - 0.0014 18.5 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_9 PF13426.7 KIR66619.1 - 0.018 15.3 0.0 0.13 12.5 0.0 2.1 1 1 1 2 2 2 0 PAS domain HATPase_c_3 PF13589.6 KIR66619.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zincin_1 PF06262.11 KIR66621.1 - 4.3e-33 113.3 0.7 5.7e-33 112.9 0.7 1.2 1 0 0 1 1 1 1 Zincin-like metallopeptidase GIT_SHD PF08518.11 KIR66621.1 - 0.022 14.4 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT DUF3810 PF12725.7 KIR66621.1 - 0.23 10.8 0.1 0.31 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2587 PF10759.9 KIR66622.1 - 1.8e-75 251.8 1.6 2.3e-75 251.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) Bim_N PF06773.11 KIR66623.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Bim protein N-terminus Jag_N PF14804.6 KIR66623.1 - 0.16 12.3 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Jag N-terminus GerE PF00196.19 KIR66624.1 - 3.3e-11 42.5 0.0 6.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 KIR66624.1 - 9e-11 42.5 0.5 9e-11 42.5 0.5 3.7 3 2 0 3 3 3 1 AAA ATPase domain ThiS PF02597.20 KIR66625.1 - 1.1e-09 38.8 0.0 1.2e-09 38.6 0.0 1.0 1 0 0 1 1 1 1 ThiS family Peptidase_A24 PF01478.18 KIR66626.1 - 1.6e-08 34.9 13.5 1.6e-08 34.9 13.5 2.5 1 1 0 2 2 2 1 Type IV leader peptidase family EamA PF00892.20 KIR66627.1 - 1.7e-30 106.0 33.3 2.8e-18 66.4 13.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KIR66627.1 - 0.0049 16.2 1.3 0.0077 15.6 1.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family TMEM234 PF10639.9 KIR66627.1 - 0.023 14.8 3.9 0.046 13.8 1.1 2.6 3 0 0 3 3 3 0 Putative transmembrane family 234 MoCF_biosynth PF00994.24 KIR66629.1 - 1.1e-29 103.0 0.3 1.2e-29 102.8 0.3 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain CPP1-like PF11833.8 KIR66630.1 - 0.18 11.4 3.6 0.28 10.8 3.6 1.5 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AMP-binding PF00501.28 KIR66630.1 - 1.8 7.1 4.8 3.3 6.2 4.8 1.4 1 1 0 1 1 1 0 AMP-binding enzyme SSB PF00436.25 KIR66631.1 - 8.5e-29 99.7 0.0 1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 KIR66631.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_S3_C PF00189.20 KIR66631.1 - 0.01 16.3 0.1 0.016 15.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain tRNA_anti_2 PF13742.6 KIR66631.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GRP PF07172.11 KIR66631.1 - 0.037 14.7 9.5 0.056 14.1 9.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family NNMT_PNMT_TEMT PF01234.17 KIR66631.1 - 0.25 10.5 0.0 0.33 10.1 0.0 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family GidB PF02527.15 KIR66633.1 - 7.2e-46 155.8 0.0 9.6e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 KIR66633.1 - 0.0055 16.3 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KIR66633.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Phenol_monoox PF04663.12 KIR66633.1 - 0.081 13.1 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Phenol hydroxylase conserved region DNA_topoisoIV PF00521.20 KIR66634.1 - 3.7e-141 470.9 0.1 7.7e-96 321.6 0.0 2.2 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 KIR66634.1 - 2.4e-75 247.8 9.9 8.7e-13 47.5 0.2 6.7 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller LAGLIDADG_3 PF14528.6 KIR66634.1 - 4.2e-20 71.8 0.3 4.9e-16 58.8 0.1 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain Intein_splicing PF14890.6 KIR66634.1 - 4.2e-08 33.2 0.0 9.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Intein splicing domain LAGLIDADG_WhiA PF14527.6 KIR66634.1 - 0.041 14.0 1.0 0.85 9.7 0.0 2.8 3 0 0 3 3 3 0 WhiA LAGLIDADG-like domain TPD52 PF04201.15 KIR66634.1 - 0.15 11.6 1.1 0.27 10.8 1.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Sua5_yciO_yrdC PF01300.18 KIR66635.1 - 2e-52 177.3 0.0 2.6e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KIR66635.1 - 2.7e-21 76.6 0.0 4.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding NAD_binding_10 PF13460.6 KIR66636.1 - 1e-15 58.1 0.6 1.6e-15 57.4 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIR66636.1 - 1.4e-08 34.5 0.7 2.7e-08 33.6 0.7 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIR66636.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KIR66636.1 - 0.00015 21.0 0.2 0.00053 19.2 0.1 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KIR66636.1 - 0.0018 17.8 0.4 0.0026 17.3 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KIR66636.1 - 0.0041 16.2 0.0 0.0073 15.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KIR66636.1 - 0.07 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 KR domain Hydrolase_4 PF12146.8 KIR66637.1 - 7.6e-06 25.4 1.0 9.3e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 KIR66637.1 - 0.00046 19.7 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_1 PF00561.20 KIR66637.1 - 0.013 15.1 0.0 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 KIR66637.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Gaa1 PF04114.14 KIR66637.1 - 10 5.0 8.5 16 4.4 8.5 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component HMGL-like PF00682.19 KIR66640.1 - 2.7e-48 164.8 0.3 3.1e-48 164.7 0.3 1.0 1 0 0 1 1 1 1 HMGL-like Lipase_GDSL_2 PF13472.6 KIR66640.1 - 0.041 14.3 0.0 8.7 6.7 0.0 2.4 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Gram_pos_anchor PF00746.21 KIR66641.1 - 2.8 8.0 11.0 0.86 9.6 1.9 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Glyco_tran_WecB PF03808.13 KIR66642.1 - 3.7e-52 176.7 0.0 5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.21 KIR66643.1 - 1.2e-35 123.1 0.1 6.7e-35 120.7 0.1 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR66643.1 - 3.7e-26 92.3 0.0 4.4e-25 88.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIR66643.1 - 1.7e-10 40.5 0.1 7.9e-10 38.3 0.1 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIR66643.1 - 1.7e-08 34.0 0.0 2.1e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIR66643.1 - 7e-08 32.0 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KIR66643.1 - 2.8e-07 29.8 0.0 4.3e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KIR66643.1 - 0.001 18.5 0.1 0.004 16.6 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIR66643.1 - 0.023 14.3 0.1 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIR66643.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 KR domain DUF21 PF01595.20 KIR66644.1 - 7.8e-36 123.4 0.4 1.2e-35 122.8 0.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 KIR66644.1 - 3.2e-22 78.3 2.4 3.7e-22 78.1 0.5 2.0 1 1 1 2 2 2 1 Transporter associated domain CBS PF00571.28 KIR66644.1 - 8.8e-07 29.3 2.2 0.00045 20.6 0.3 2.7 3 0 0 3 3 3 2 CBS domain AtuA PF07287.11 KIR66644.1 - 0.08 11.6 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA NLPC_P60 PF00877.19 KIR66645.1 - 1.1e-25 89.6 0.0 2.4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 KIR66645.1 - 0.0066 16.4 0.1 0.057 13.3 0.1 2.3 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase Fzo_mitofusin PF04799.13 KIR66645.1 - 0.022 14.3 3.1 0.04 13.5 0.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF3450 PF11932.8 KIR66645.1 - 0.037 13.3 7.2 1.1 8.5 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) THOC7 PF05615.13 KIR66645.1 - 0.043 14.1 9.2 0.069 13.4 2.6 2.1 1 1 0 2 2 2 0 Tho complex subunit 7 Jnk-SapK_ap_N PF09744.9 KIR66645.1 - 0.048 13.9 9.4 0.11 12.7 3.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF1175 PF06672.11 KIR66645.1 - 0.059 13.1 0.3 2.8 7.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) HemX PF04375.14 KIR66645.1 - 0.066 12.5 6.7 0.88 8.8 0.2 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_C92 PF05708.12 KIR66645.1 - 0.081 13.0 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family GAS PF13851.6 KIR66645.1 - 0.15 11.4 10.3 0.046 13.1 1.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 KIR66645.1 - 0.17 12.5 9.9 2.5 8.8 0.6 3.5 2 2 2 4 4 4 0 SlyX LRAT PF04970.13 KIR66645.1 - 0.17 12.2 0.1 0.5 10.7 0.0 1.8 2 0 0 2 2 2 0 Lecithin retinol acyltransferase YtxH PF12732.7 KIR66645.1 - 0.21 12.1 0.3 0.21 12.1 0.3 2.1 2 0 0 2 2 2 0 YtxH-like protein DUF349 PF03993.12 KIR66645.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF5082 PF16888.5 KIR66645.1 - 0.39 11.0 8.7 0.27 11.5 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) PI3K_P85_iSH2 PF16454.5 KIR66645.1 - 0.4 10.3 7.1 2.9 7.5 0.4 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Adhesin_P1_N PF18652.1 KIR66645.1 - 0.49 10.5 5.7 0.82 9.7 0.1 2.6 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Prefoldin_2 PF01920.20 KIR66645.1 - 1 9.3 11.4 5.3 7.1 0.5 2.6 2 1 1 3 3 3 0 Prefoldin subunit YlqD PF11068.8 KIR66645.1 - 1.6 9.1 9.1 2.2 8.7 1.5 2.3 2 0 0 2 2 2 0 YlqD protein AAA_13 PF13166.6 KIR66645.1 - 1.6 7.3 8.5 2.1 6.9 3.6 2.0 2 0 0 2 2 2 0 AAA domain DUF1664 PF07889.12 KIR66645.1 - 2 8.4 4.6 11 6.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KIR66645.1 - 2.1 8.9 7.6 5.1 7.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 GCN5L1 PF06320.13 KIR66645.1 - 2.3 8.4 7.7 1.3 9.2 1.1 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) TPR_MLP1_2 PF07926.12 KIR66645.1 - 2.6 8.1 11.6 3.3 7.8 3.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.6 KIR66645.1 - 3.1 7.9 9.1 13 5.8 3.6 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF5595 PF18077.1 KIR66645.1 - 5.8 7.1 5.1 1 9.5 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF4407 PF14362.6 KIR66645.1 - 6.3 6.0 10.8 6.4 6.0 4.0 1.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KIR66645.1 - 7.2 6.5 11.3 10 6.0 2.4 2.6 2 0 0 2 2 2 0 Septum formation initiator Colicin_Pyocin PF01320.18 KIR66646.1 - 0.0091 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Colicin immunity protein / pyocin immunity protein Dimerisation PF08100.11 KIR66646.1 - 0.17 11.9 0.4 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 Dimerisation domain HTH_17 PF12728.7 KIR66647.1 - 1e-08 35.3 0.2 1.2e-08 35.0 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain AbiEi_4 PF13338.6 KIR66647.1 - 0.00026 21.1 0.7 0.44 10.7 0.2 2.1 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin HTH_31 PF13560.6 KIR66647.1 - 0.015 15.6 1.2 0.052 13.9 0.2 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_18 PF12833.7 KIR66647.1 - 0.035 14.4 0.3 0.042 14.1 0.3 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 KIR66647.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix DUF2637 PF10935.8 KIR66648.1 - 4e-06 26.8 12.4 5.9e-06 26.3 12.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2637) DUF4231 PF14015.6 KIR66648.1 - 0.12 12.8 6.0 2.4 8.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) FtsK_SpoIIIE PF01580.18 KIR66649.1 - 1.4e-11 44.3 0.0 5.6e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 FtsK/SpoIIIE family FATC PF02260.20 KIR66650.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 FATC domain Pribosyltran PF00156.27 KIR66651.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CT_C_D PF02682.16 KIR66652.1 - 3.3e-57 193.5 0.5 3.8e-57 193.3 0.5 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D 2-oxoacid_dh PF00198.23 KIR66653.1 - 7.1e-76 254.7 0.0 9.1e-76 254.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIR66653.1 - 4.9e-22 77.5 0.1 1e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIR66653.1 - 1.6e-12 47.6 0.4 1.6e-12 47.6 0.4 2.6 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIR66653.1 - 0.031 14.1 0.0 0.94 9.4 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like PAP2 PF01569.21 KIR66654.1 - 1.4e-06 28.1 10.4 1.4e-06 28.1 10.4 2.0 1 1 1 2 2 2 1 PAP2 superfamily Fusion_F0 PF13044.6 KIR66654.1 - 0.074 11.7 0.7 0.096 11.3 0.7 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Pribosyltran PF00156.27 KIR66655.1 - 4e-13 49.2 0.5 5e-13 48.9 0.5 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIR66655.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PNKP_ligase PF16542.5 KIR66656.1 - 4.8e-135 450.2 0.0 7e-135 449.6 0.0 1.2 1 0 0 1 1 1 1 PNKP adenylyltransferase domain, ligase domain PNKP-ligase_C PF16536.5 KIR66656.1 - 1.3e-25 89.5 2.6 1.3e-25 89.5 2.6 2.1 2 0 0 2 2 2 1 PNKP adenylyltransferase domain, C-terminal region AAA_33 PF13671.6 KIR66656.1 - 3.7e-24 85.5 0.4 7.3e-24 84.6 0.4 1.5 1 0 0 1 1 1 1 AAA domain Metallophos PF00149.28 KIR66656.1 - 1.5e-10 41.9 0.0 3.3e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_18 PF13238.6 KIR66656.1 - 0.00096 19.7 0.1 0.0054 17.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIR66656.1 - 0.0025 18.2 0.3 0.0056 17.1 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 KIR66656.1 - 0.0034 17.2 4.1 0.073 12.9 4.1 2.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 KIR66656.1 - 0.028 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Metallophos_2 PF12850.7 KIR66656.1 - 0.035 14.3 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain AAA_24 PF13479.6 KIR66656.1 - 0.042 13.6 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIR66656.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KIR66656.1 - 0.18 12.3 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter LDcluster4 PF18306.1 KIR66657.1 - 1.3e-08 34.5 0.8 3.7e-06 26.6 0.5 2.3 2 0 0 2 2 2 2 SLOG cluster4 family Lysine_decarbox PF03641.14 KIR66657.1 - 0.023 14.8 0.2 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Possible lysine decarboxylase MTES_1575 PF18741.1 KIR66658.1 - 1.8e-06 28.1 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 KIR66658.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MaoC_dehydratas PF01575.19 KIR66659.1 - 4.3e-16 58.6 0.1 4.2e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIR66659.1 - 0.00041 20.5 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase YbjQ_1 PF01906.17 KIR66660.1 - 7.1e-25 87.7 0.0 8.7e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding HTH_17 PF12728.7 KIR66661.1 - 4.1e-13 49.3 0.1 4.7e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 KIR66661.1 - 2.8e-08 33.4 0.2 6.8e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR_1 PF13411.6 KIR66661.1 - 9.9e-07 28.8 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_29 PF13551.6 KIR66661.1 - 0.0021 18.1 0.1 0.0041 17.1 0.1 1.5 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KIR66661.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.9 1 1 0 1 1 1 0 Homeodomain-like domain AbiEi_4 PF13338.6 KIR66661.1 - 0.027 14.6 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Terminase_5 PF06056.12 KIR66661.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_ISL3 PF13542.6 KIR66661.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TadE PF07811.12 KIR66662.1 - 1.8e-05 24.9 5.7 3.1e-05 24.1 5.7 1.4 1 0 0 1 1 1 1 TadE-like protein Tad PF13400.6 KIR66662.1 - 5.5 7.4 17.7 21 5.5 17.7 1.9 1 1 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like TadE PF07811.12 KIR66663.1 - 1e-06 28.9 4.5 1.6e-06 28.3 4.5 1.3 1 0 0 1 1 1 1 TadE-like protein Tad PF13400.6 KIR66663.1 - 0.026 14.8 6.5 0.056 13.8 6.5 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Trp_oprn_chp PF09534.10 KIR66663.1 - 0.16 11.8 10.3 0.19 11.5 10.3 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) T2SSF PF00482.23 KIR66664.1 - 7e-10 38.9 0.1 7e-10 38.9 0.1 2.1 3 0 0 3 3 3 1 Type II secretion system (T2SS), protein F FTR1 PF03239.14 KIR66664.1 - 0.19 10.8 3.1 0.068 12.3 0.4 1.6 2 0 0 2 2 2 0 Iron permease FTR1 family T2SSF PF00482.23 KIR66665.1 - 1.2e-07 31.7 0.8 1.2e-07 31.7 0.8 2.6 4 0 0 4 4 4 1 Type II secretion system (T2SS), protein F TetR_C_20 PF17925.1 KIR66665.1 - 0.037 14.3 0.6 0.082 13.2 0.6 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ion_trans_2 PF07885.16 KIR66665.1 - 1.3 9.0 4.4 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Ion channel DUF1176 PF06674.11 KIR66667.1 - 0.29 10.5 2.1 0.44 9.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) HTH_31 PF13560.6 KIR66668.1 - 1.1e-05 25.6 2.9 0.0093 16.3 0.0 3.2 4 0 0 4 4 4 2 Helix-turn-helix domain DDE_Tnp_4 PF13359.6 KIR66669.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR66669.1 - 1.3e-13 50.4 0.0 2.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR66669.1 - 3.8e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR66669.1 - 0.018 15.1 0.1 0.064 13.3 0.0 1.9 2 0 0 2 2 2 0 Stage III sporulation protein D LZ_Tnp_IS481 PF13011.6 KIR66669.1 - 0.07 13.7 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HrpJ PF07201.11 KIR66670.1 - 0.019 15.3 0.4 0.025 14.9 0.4 1.1 1 0 0 1 1 1 0 HrpJ-like domain EFG_II PF14492.6 KIR66670.1 - 0.063 13.4 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Elongation Factor G, domain II RNA_pol_Rpb1_6 PF04992.14 KIR66670.1 - 0.19 11.5 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 HTH_3 PF01381.22 KIR66671.1 - 2.6e-15 56.2 0.1 3.6e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIR66671.1 - 8.2e-11 42.1 1.2 1.6e-10 41.1 1.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIR66671.1 - 5.3e-10 39.2 0.0 7.7e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KIR66671.1 - 4.1e-05 23.9 0.0 6.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Cupin_2 PF07883.11 KIR66671.1 - 0.0016 18.1 0.2 0.0024 17.6 0.2 1.2 1 0 0 1 1 1 1 Cupin domain HTH_25 PF13413.6 KIR66671.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KIR66671.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 KIR66671.1 - 0.14 11.9 3.6 0.16 11.8 0.4 2.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain MFS_1 PF07690.16 KIR66672.1 - 1.1e-09 37.7 66.2 2.9e-09 36.3 55.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR66672.1 - 4.2 6.1 12.3 5.4 5.8 0.2 2.3 2 0 0 2 2 2 0 MFS_1 like family SpoIIE PF07228.12 KIR66673.1 - 8.2e-14 52.0 2.7 6.5e-13 49.0 2.7 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 KIR66673.1 - 8.1e-06 25.8 0.1 2.5e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR66674.1 - 3e-24 85.7 0.0 5.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR66674.1 - 3.6e-18 65.4 0.3 3.6e-18 65.4 0.3 2.8 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Rootletin PF15035.6 KIR66674.1 - 0.0011 19.1 2.3 0.0018 18.3 2.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Taxilin PF09728.9 KIR66674.1 - 0.027 13.7 0.3 0.038 13.2 0.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ATP-synt_D PF01813.17 KIR66674.1 - 0.033 14.0 0.9 0.066 13.0 0.9 1.5 1 0 0 1 1 1 0 ATP synthase subunit D DUF3450 PF11932.8 KIR66674.1 - 0.036 13.4 2.7 0.056 12.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KIR66674.1 - 0.096 13.1 1.2 0.27 11.7 1.0 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.11 KIR66674.1 - 0.27 11.8 3.2 19 5.9 3.5 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HATPase_c_2 PF13581.6 KIR66674.1 - 0.38 10.7 4.0 0.4 10.7 0.0 3.0 4 2 0 4 4 4 0 Histidine kinase-like ATPase domain ZapB PF06005.12 KIR66674.1 - 1 9.8 7.4 2.5 8.6 7.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.12 KIR66674.1 - 1.5 9.3 4.7 1 9.8 2.6 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KIR66674.1 - 1.5 7.7 6.6 6.6 5.5 6.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 KIR66674.1 - 3.9 5.9 13.6 1.5 7.3 10.2 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family ABC2_membrane_3 PF12698.7 KIR66675.1 - 0.29 10.2 5.9 1.3 8.1 0.8 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Abhydrolase_1 PF00561.20 KIR66676.1 - 2.8e-23 82.9 0.5 2.2e-22 79.9 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIR66676.1 - 3.1e-23 83.5 11.8 3.7e-23 83.3 11.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIR66676.1 - 2e-08 33.8 0.2 3.1e-08 33.2 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIR66676.1 - 0.018 13.8 0.0 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 Ndr family ABC_tran PF00005.27 KIR66678.1 - 2.5e-29 102.5 0.0 3.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66678.1 - 1.5e-11 44.7 0.4 2.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR66678.1 - 2.4e-07 30.4 0.0 0.012 15.1 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR66678.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KIR66678.1 - 0.00026 19.9 0.5 0.34 9.7 0.0 2.4 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KIR66678.1 - 0.00093 19.5 0.3 0.0093 16.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 KIR66678.1 - 0.0014 18.3 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR66678.1 - 0.0023 18.3 1.1 0.0092 16.4 1.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KIR66678.1 - 0.0027 18.3 0.0 0.0043 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIR66678.1 - 0.0042 16.7 1.5 1.9 8.0 0.1 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KIR66678.1 - 0.0045 16.7 0.2 0.015 15.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR66678.1 - 0.034 14.3 1.3 0.24 11.6 0.1 2.4 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KIR66678.1 - 0.037 13.7 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 KIR66678.1 - 0.041 13.6 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KIR66678.1 - 0.045 14.3 0.0 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain HIG_1_N PF04588.13 KIR66678.1 - 0.056 13.7 0.3 4.1 7.7 0.1 2.8 2 0 0 2 2 2 0 Hypoxia induced protein conserved region SbcCD_C PF13558.6 KIR66678.1 - 0.072 13.3 0.1 1 9.7 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KIR66678.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KIR66678.1 - 0.085 12.9 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KIR66678.1 - 0.086 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR66678.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIR66678.1 - 0.16 11.8 0.1 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Adeno_IVa2 PF02456.15 KIR66678.1 - 0.25 10.1 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Amidase PF01425.21 KIR66679.1 - 2.7e-59 201.3 8.8 7.2e-38 130.7 7.7 3.6 1 1 2 3 3 3 3 Amidase Peptidase_M4 PF01447.18 KIR66680.1 - 6.4e-49 166.2 5.1 2.9e-48 164.1 3.8 2.3 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 KIR66680.1 - 7.6e-45 152.8 0.0 1.6e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain P_proprotein PF01483.20 KIR66680.1 - 2.9e-19 68.9 0.1 7e-19 67.6 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain FTP PF07504.13 KIR66680.1 - 2.7e-08 33.5 0.8 1e-07 31.6 0.8 2.1 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Sigma70_r2 PF04542.14 KIR66681.1 - 5.4e-21 74.1 2.6 5.4e-21 74.1 2.6 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR66681.1 - 1.1e-14 53.7 0.0 3.3e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KIR66681.1 - 3.9e-12 45.7 0.0 8.6e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR66681.1 - 6.4e-05 22.9 0.0 9.3e-05 22.4 0.0 1.2 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 KIR66681.1 - 0.012 15.3 0.0 0.049 13.4 0.0 2.1 1 1 0 1 1 1 0 Homeodomain-like domain GerE PF00196.19 KIR66681.1 - 0.015 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 KIR66681.1 - 0.017 15.2 0.2 0.26 11.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 KIR66681.1 - 0.023 14.6 0.3 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 MarR family DUF742 PF05331.11 KIR66681.1 - 0.037 13.8 0.1 0.1 12.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF742) WXG100 PF06013.12 KIR66682.1 - 2.2e-12 47.0 12.5 3e-12 46.6 12.5 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF4510 PF14971.6 KIR66682.1 - 0.0013 19.1 6.8 0.0014 19.0 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4510) T7SS_ESX_EspC PF10824.8 KIR66682.1 - 0.023 15.1 9.0 0.031 14.8 9.0 1.2 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm OmpH PF03938.14 KIR66682.1 - 0.43 10.9 6.0 0.56 10.5 6.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TraG_N PF07916.11 KIR66682.1 - 7.2 5.3 7.1 8.1 5.2 7.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SseB PF07179.12 KIR66683.1 - 1.4e-20 73.8 0.0 1.6e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 SseB protein N-terminal domain Peptidase_M6 PF05547.11 KIR66684.1 - 2.7e-104 349.8 23.4 6e-104 348.7 23.4 1.4 1 1 0 1 1 1 1 Immune inhibitor A peptidase M6 Reprolysin_5 PF13688.6 KIR66684.1 - 0.011 15.9 0.1 0.032 14.4 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 HxlR PF01638.17 KIR66685.1 - 1.1e-17 63.7 0.0 1.4e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_27 PF13463.6 KIR66685.1 - 0.07 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF559 PF04480.12 KIR66686.1 - 3.4e-11 43.0 0.1 1.4e-10 41.0 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 KIR66686.1 - 0.00064 19.9 0.1 0.0014 18.7 0.1 1.6 1 1 0 1 1 1 1 REase_MTES_1575 VHL PF01847.16 KIR66687.1 - 1.2e-10 41.1 0.2 1.5e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 VHL beta domain HTH_17 PF12728.7 KIR66688.1 - 0.0037 17.4 0.0 0.0073 16.5 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain Phage_AlpA PF05930.12 KIR66688.1 - 0.0044 16.8 0.1 0.0068 16.2 0.1 1.3 1 1 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) Sigma70_r4 PF04545.16 KIR66688.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 KIR66688.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain STAS PF01740.21 KIR66690.1 - 1.3e-18 66.8 0.0 1.4e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIR66690.1 - 6.6e-15 55.2 1.1 8.3e-15 54.9 1.1 1.2 1 0 0 1 1 1 1 STAS domain DUF559 PF04480.12 KIR66691.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) Thymidylate_kin PF02223.17 KIR66692.1 - 4.4e-51 173.2 0.0 5.9e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase MFS_1 PF07690.16 KIR66692.1 - 1.1e-11 44.3 63.7 4e-07 29.3 39.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KIR66692.1 - 3.1e-09 35.8 37.8 4.7e-09 35.2 37.8 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector AAA_28 PF13521.6 KIR66692.1 - 2.9e-07 30.9 0.1 5.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain MFS_2 PF13347.6 KIR66692.1 - 0.00013 20.7 17.4 0.00013 20.7 17.4 2.1 1 1 0 2 2 2 2 MFS/sugar transport protein AAA_30 PF13604.6 KIR66692.1 - 0.00024 20.9 0.2 0.00048 19.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIR66692.1 - 0.0028 18.1 0.0 1.4 9.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIR66692.1 - 0.0055 16.9 0.1 0.013 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF4350 PF14258.6 KIR66692.1 - 0.031 14.7 0.6 0.15 12.5 0.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) AAA_18 PF13238.6 KIR66692.1 - 0.078 13.5 0.0 0.82 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIR66692.1 - 0.15 12.4 1.0 0.61 10.4 1.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 KIR66692.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KIR66692.1 - 0.17 11.9 0.1 2.3 8.3 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_ATPase PF09818.9 KIR66692.1 - 3.6 6.3 5.0 0.32 9.7 0.1 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Beta-lactamase PF00144.24 KIR66693.1 - 3e-67 227.2 9.0 3e-67 227.2 9.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KIR66693.1 - 7.1e-06 25.8 0.0 0.049 13.2 0.0 2.6 3 0 0 3 3 3 2 Beta-lactamase enzyme family Glyco_transf_9 PF01075.17 KIR66694.1 - 2e-31 109.2 0.0 2.6e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glycos_transf_2 PF00535.26 KIR66695.1 - 1.5e-12 47.6 0.0 2.6e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66695.1 - 3e-09 37.1 0.1 4e-09 36.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIR66695.1 - 0.00099 18.6 0.0 0.031 13.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KIR66695.1 - 0.018 15.0 0.1 0.1 12.5 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Glyoxalase PF00903.25 KIR66697.1 - 4.5e-17 62.4 0.0 5.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIR66697.1 - 4.2e-07 30.7 0.0 7.4e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KIR66697.1 - 9.5e-07 28.8 0.0 0.0051 16.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain GntR PF00392.21 KIR66698.1 - 1.8e-14 53.1 0.0 2e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 KIR66698.1 - 0.00024 21.0 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 KIR66698.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.4 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 KIR66698.1 - 0.064 13.6 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator DUF4262 PF14081.6 KIR66698.1 - 0.16 12.2 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) CRISPR_assoc PF08798.11 KIR66699.1 - 2e-67 227.6 1.9 2.2e-67 227.5 1.9 1.0 1 0 0 1 1 1 1 CRISPR associated protein AMP-binding PF00501.28 KIR66700.1 - 5.9e-08 31.7 0.2 4.9e-06 25.4 0.1 2.0 2 0 0 2 2 2 2 AMP-binding enzyme MazE_antitoxin PF04014.18 KIR66700.1 - 0.018 14.9 0.2 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin PDZ_6 PF17820.1 KIR66700.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 PDZ domain Eco57I PF07669.11 KIR66701.1 - 5.4e-08 33.3 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 KIR66701.1 - 7.1e-08 32.6 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain N6_Mtase PF02384.16 KIR66701.1 - 8e-05 22.0 0.0 0.00045 19.6 0.0 1.9 1 1 0 1 1 1 1 N-6 DNA Methylase PNP_UDP_1 PF01048.20 KIR66702.1 - 2.3e-14 53.2 10.8 2.9e-14 52.9 10.8 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Xan_ur_permease PF00860.20 KIR66703.1 - 4.2e-28 98.1 37.3 6.1e-28 97.6 37.3 1.2 1 0 0 1 1 1 1 Permease family MarR PF01047.22 KIR66704.1 - 4.8e-15 55.2 0.0 1.1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KIR66704.1 - 4.1e-11 42.6 1.5 6.5e-11 42.0 0.3 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 KIR66704.1 - 6.3e-08 33.0 0.1 1.4e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KIR66704.1 - 3.1e-05 23.7 6.2 2.2 8.1 0.2 4.1 3 1 0 3 3 3 3 IclR helix-turn-helix domain TrmB PF01978.19 KIR66704.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KIR66704.1 - 0.0013 18.6 0.6 0.026 14.5 0.0 2.4 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KIR66704.1 - 0.0023 18.1 0.0 0.0085 16.3 0.0 1.8 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 KIR66704.1 - 0.0031 17.0 0.4 0.0095 15.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding FliG_M PF14841.6 KIR66704.1 - 0.0037 17.4 0.4 0.094 13.0 0.1 2.3 2 0 0 2 2 2 1 FliG middle domain Rrf2 PF02082.20 KIR66704.1 - 0.011 16.1 0.0 0.037 14.4 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HxlR PF01638.17 KIR66704.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix SMC_ScpB PF04079.16 KIR66704.1 - 0.017 14.8 0.1 0.029 14.0 0.1 1.5 1 1 0 1 1 1 0 Segregation and condensation complex subunit ScpB HTH_20 PF12840.7 KIR66704.1 - 0.022 14.8 2.4 0.037 14.1 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain SCP2_2 PF13530.6 KIR66704.1 - 0.1 13.0 0.4 0.16 12.4 0.0 1.6 2 0 0 2 2 2 0 Sterol carrier protein domain HTH_32 PF13565.6 KIR66704.1 - 0.67 10.6 6.2 13 6.5 0.5 3.0 2 2 0 2 2 2 0 Homeodomain-like domain LigT_PEase PF02834.16 KIR66705.1 - 7.2e-15 54.9 0.4 4.1e-06 26.9 0.0 2.7 2 1 1 3 3 3 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 KIR66705.1 - 4.1e-09 36.5 0.0 5.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily ABC2_membrane PF01061.24 KIR66706.1 - 4.2e-19 68.8 10.7 4.2e-19 68.8 10.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter p450 PF00067.22 KIR66707.1 - 2.9e-32 112.0 0.0 1.3e-27 96.7 0.0 3.1 1 1 0 1 1 1 1 Cytochrome P450 Hemerythrin PF01814.23 KIR66708.1 - 2.9e-15 57.0 20.2 4.2e-13 50.1 11.7 1.8 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain INT_SG_DDX_CT_C PF15300.6 KIR66708.1 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 INTS6/SAGE1/DDX26B/CT45 C-terminus FUSC PF04632.12 KIR66708.1 - 1.2 7.6 5.8 1.3 7.5 5.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Putative_PNPOx PF01243.20 KIR66709.1 - 3.3e-11 43.2 0.2 4.3e-11 42.9 0.2 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KIR66709.1 - 0.0004 20.0 0.0 0.00042 19.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like ABC_tran PF00005.27 KIR66710.1 - 4.7e-32 111.4 0.0 5.8e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KIR66710.1 - 1.1e-05 25.9 0.6 1.7e-05 25.3 0.5 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIR66710.1 - 7.8e-05 22.3 0.1 0.00017 21.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KIR66710.1 - 0.0014 18.3 4.5 0.056 13.0 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIR66710.1 - 0.0025 17.6 2.4 0.017 14.8 2.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIR66710.1 - 0.0074 16.1 0.0 0.05 13.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIR66710.1 - 0.0092 15.9 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 KIR66710.1 - 0.037 13.5 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR66710.1 - 0.047 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIR66710.1 - 0.05 13.8 0.2 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIR66710.1 - 0.051 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KIR66710.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 KIR66710.1 - 0.075 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIR66710.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIR66710.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KIR66710.1 - 0.11 11.5 0.7 0.25 10.4 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 KIR66710.1 - 0.15 10.8 0.1 3.6 6.3 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Peptidase_S8 PF00082.22 KIR66711.1 - 1.5e-40 139.4 0.2 2.4e-40 138.6 0.2 1.3 1 1 0 1 1 1 1 Subtilase family Pro_CA PF00484.19 KIR66712.1 - 5e-34 117.8 0.4 6.4e-34 117.5 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF305 PF03713.13 KIR66713.1 - 5e-57 192.3 11.3 6.7e-57 191.9 11.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 KIR66713.1 - 1.5e-15 57.7 3.1 5.9e-15 55.7 3.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4142) PspB PF06667.12 KIR66714.1 - 0.75 9.9 5.4 2.5 8.2 2.4 2.3 1 1 1 2 2 2 0 Phage shock protein B Abhydrolase_1 PF00561.20 KIR66715.1 - 2.9e-26 92.7 0.0 4e-25 88.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIR66715.1 - 1.7e-14 53.8 0.2 4.4e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KIR66715.1 - 2.3e-06 27.1 0.2 0.0036 16.6 0.1 3.4 2 2 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KIR66715.1 - 0.064 13.1 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase DUF3152 PF11350.8 KIR66716.1 - 7.7e-41 140.1 0.0 1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3152) Reprolysin_3 PF13582.6 KIR66716.1 - 0.17 12.4 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like STAS_2 PF13466.6 KIR66717.1 - 5.6e-18 65.1 3.9 7.3e-18 64.7 3.9 1.2 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KIR66717.1 - 9.5e-12 44.6 0.0 1e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 STAS domain ANTAR PF03861.14 KIR66718.1 - 1.6e-19 69.5 2.1 1.6e-19 69.5 2.1 2.4 4 0 0 4 4 4 1 ANTAR domain GAF_2 PF13185.6 KIR66718.1 - 4.5e-10 40.0 0.5 7.5e-10 39.2 0.5 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KIR66718.1 - 0.00039 21.1 0.2 0.00056 20.5 0.2 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KIR66718.1 - 0.028 14.8 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 GAF domain Glycos_transf_2 PF00535.26 KIR66719.1 - 1.3e-31 109.7 0.0 2.6e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66719.1 - 6.9e-18 65.4 0.0 1.4e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR66719.1 - 4.9e-09 36.1 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KIR66719.1 - 0.032 14.7 0.0 0.15 12.6 0.0 2.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2993 PF11209.8 KIR66719.1 - 0.085 13.1 4.5 0.13 12.5 3.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2993) Sigma70_r4_2 PF08281.12 KIR66720.1 - 4.4e-13 48.7 0.1 8.3e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 KIR66720.1 - 3.8e-08 33.4 1.9 5.2e-08 33.0 1.9 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 KIR66720.1 - 5.6e-07 29.0 0.3 1.1e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR66720.1 - 6.2e-07 29.1 5.3 7.8e-07 28.8 3.6 2.1 2 0 0 2 2 2 1 Sigma-70 region 2 Glyco_hydro_53 PF07745.13 KIR66721.1 - 2.4e-100 335.9 2.8 2.8e-100 335.6 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Sigma70_r4_2 PF08281.12 KIR66722.1 - 1.2e-14 53.7 0.2 2e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66722.1 - 1e-09 37.7 0.0 1.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 KIR66722.1 - 1.1e-06 28.4 0.8 2.1e-06 27.4 0.8 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 KIR66722.1 - 0.015 15.2 0.7 0.021 14.7 0.7 1.4 1 1 0 1 1 1 0 ECF sigma factor HTH_23 PF13384.6 KIR66722.1 - 0.088 12.6 0.7 0.45 10.4 0.7 2.2 1 1 0 1 1 1 0 Homeodomain-like domain Ricin_B_lectin PF00652.22 KIR66723.1 - 2.2e-28 99.0 12.1 1.1e-27 96.8 12.2 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66723.1 - 2e-24 86.2 24.4 7.5e-12 45.8 4.1 3.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Peptidase_S9 PF00326.21 KIR66723.1 - 6.3e-09 35.6 0.0 0.00039 19.9 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIR66723.1 - 1.8e-07 30.7 0.3 0.0013 18.0 0.3 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KIR66723.1 - 6.6e-07 29.2 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIR66723.1 - 1.1e-06 28.4 0.0 3.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KIR66723.1 - 1.2e-06 27.7 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 KIR66723.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIR66723.1 - 0.00054 18.7 0.5 0.0078 14.9 0.2 2.2 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.13 KIR66723.1 - 0.00098 17.7 0.1 0.021 13.4 0.0 2.2 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 KIR66723.1 - 0.0011 18.7 0.1 0.083 12.5 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KIR66723.1 - 0.0012 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.9 KIR66723.1 - 0.0019 17.8 1.6 0.14 11.6 0.2 2.4 1 1 1 2 2 2 2 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KIR66723.1 - 0.0022 18.6 1.6 0.0036 18.0 1.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ET PF01684.16 KIR66723.1 - 0.012 15.9 5.4 2.4 8.6 0.2 3.2 1 1 2 3 3 3 0 ET module Esterase PF00756.20 KIR66723.1 - 0.055 13.1 8.0 0.3 10.7 8.0 2.0 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KIR66723.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KIR66723.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BAAT_C PF08840.11 KIR66723.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 KIR66723.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) ADH_zinc_N_2 PF13602.6 KIR66724.1 - 1.4e-28 100.6 0.0 3e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR66724.1 - 2.1e-13 50.4 0.0 3.9e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR66724.1 - 2.9e-07 30.3 0.0 7.6e-05 22.6 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain IstB_IS21 PF01695.17 KIR66724.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AlaDh_PNT_C PF01262.21 KIR66724.1 - 0.017 14.4 0.4 0.024 13.9 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.8 KIR66724.1 - 0.038 13.8 0.2 0.066 13.0 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 KIR66724.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KIR66724.1 - 0.1 11.7 0.1 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Mur_ligase_C PF02875.21 KIR66724.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Barstar PF01337.18 KIR66725.1 - 1.7e-15 56.8 0.1 3.1e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Barstar (barnase inhibitor) Smr PF01713.21 KIR66726.1 - 0.043 14.2 0.1 0.085 13.2 0.1 1.4 1 1 0 1 1 1 0 Smr domain ALF PF03752.13 KIR66726.1 - 0.063 13.3 1.8 0.16 12.0 0.3 2.4 2 0 0 2 2 2 0 Short repeats of unknown function HTH_23 PF13384.6 KIR66726.1 - 0.23 11.3 2.9 0.19 11.6 0.6 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Amidinotransf PF02274.17 KIR66727.1 - 0.041 13.0 0.0 0.091 11.8 0.0 1.5 2 0 0 2 2 2 0 Amidinotransferase Methyltransf_25 PF13649.6 KIR66728.1 - 5.1e-20 72.0 0.0 8.7e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR66728.1 - 1.3e-13 51.4 0.0 2.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIR66728.1 - 1.7e-13 50.7 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR66728.1 - 3.8e-12 46.3 0.0 5.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66728.1 - 1.6e-08 35.2 0.0 2.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIR66728.1 - 9e-08 31.7 0.0 2.6e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIR66728.1 - 1.3e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KIR66728.1 - 9e-05 21.9 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 KIR66728.1 - 0.00016 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KIR66728.1 - 0.00033 20.1 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.16 KIR66728.1 - 0.00097 18.9 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 KIR66728.1 - 0.0058 16.8 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KIR66728.1 - 0.0062 15.5 0.0 1.5 7.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1698) MetW PF07021.12 KIR66728.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 KIR66728.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) tRNA_U5-meth_tr PF05958.11 KIR66728.1 - 0.24 10.4 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 KIR66728.1 - 0.29 10.5 0.1 0.39 10.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DivIVA PF05103.13 KIR66730.1 - 0.0074 16.4 0.0 0.0086 16.2 0.0 1.1 1 0 0 1 1 1 1 DivIVA protein HTH_ABP1_N PF18107.1 KIR66730.1 - 0.045 13.5 0.2 0.077 12.7 0.2 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain TPR_12 PF13424.6 KIR66731.1 - 0.0056 16.9 10.9 0.035 14.4 6.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIR66731.1 - 0.022 15.2 16.1 0.28 11.7 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIR66731.1 - 0.22 11.8 12.2 4.3 7.7 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIR66731.1 - 0.77 10.1 5.0 1.7 9.1 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIR66731.1 - 2.2 9.2 28.1 0.26 12.0 2.4 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIR66731.1 - 6.6 7.6 7.7 24 5.8 1.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pentapeptide_3 PF13576.6 KIR66732.1 - 1.3e-22 79.6 29.8 1.6e-10 41.0 7.1 3.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 KIR66732.1 - 9.7e-08 31.5 13.8 5.7e-05 22.7 0.1 5.3 1 1 4 5 5 5 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KIR66732.1 - 6.5e-05 23.0 2.8 0.0015 18.6 1.9 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) RTP1_C1 PF10363.9 KIR66732.1 - 0.18 12.0 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF11 PF01345.18 KIR66734.1 - 0.00011 22.5 7.2 0.0034 17.6 0.8 3.5 3 1 1 4 4 4 2 Domain of unknown function DUF11 MgtE_N PF03448.17 KIR66735.1 - 1e-27 96.7 8.6 2.6e-27 95.4 8.6 1.7 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 KIR66735.1 - 5.8e-15 55.5 0.6 4.9e-06 26.9 0.0 3.0 2 0 0 2 2 2 2 CBS domain FliG_M PF14841.6 KIR66735.1 - 8.3e-06 25.9 6.9 0.049 13.9 0.3 4.8 3 1 3 6 6 6 4 FliG middle domain PRC PF05239.16 KIR66735.1 - 0.00028 20.9 0.0 0.81 9.8 0.0 2.9 2 0 0 2 2 2 2 PRC-barrel domain GAF PF01590.26 KIR66735.1 - 0.0061 17.2 0.1 0.062 13.9 0.1 2.4 1 1 0 1 1 1 1 GAF domain FliG_C PF01706.16 KIR66735.1 - 0.029 14.6 0.9 1.2 9.4 0.1 2.6 1 1 1 2 2 2 0 FliG C-terminal domain FliG_N PF14842.6 KIR66735.1 - 0.032 14.8 0.3 0.59 10.7 0.1 2.7 1 1 1 2 2 2 0 FliG N-terminal domain hnRNP_Q_AcD PF18360.1 KIR66735.1 - 0.11 12.5 1.1 19 5.3 0.1 2.9 1 1 1 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain NapD PF03927.13 KIR66735.1 - 0.19 11.8 0.3 0.72 10.0 0.2 2.0 1 1 0 1 1 1 0 NapD protein DUF3459 PF11941.8 KIR66735.1 - 1.2 9.5 6.4 17 5.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3459) VKG_Carbox PF05090.14 KIR66736.1 - 3.9e-07 29.3 4.9 5.8e-07 28.7 4.9 1.3 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase MaoC_dehydratas PF01575.19 KIR66737.1 - 1.2e-15 57.2 0.0 1.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain SAM_PNT PF02198.16 KIR66737.1 - 0.17 11.9 0.0 0.41 10.6 0.0 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PDDEXK_1 PF12705.7 KIR66738.1 - 1.3e-31 110.5 0.0 1.6e-31 110.2 0.0 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 KIR66738.1 - 1.4e-05 24.6 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) Trep_Strep PF09605.10 KIR66739.1 - 0.011 15.7 2.4 0.011 15.7 0.2 1.8 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Wzy_C_2 PF11846.8 KIR66739.1 - 0.075 13.0 9.1 0.15 12.0 1.7 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal HlyIII PF03006.20 KIR66739.1 - 0.094 12.4 1.6 0.37 10.5 1.6 1.9 1 1 0 1 1 1 0 Haemolysin-III related DUF4131 PF13567.6 KIR66739.1 - 0.14 11.8 9.4 1.3 8.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MARVEL PF01284.23 KIR66739.1 - 0.31 11.1 7.0 5.9 6.9 7.0 2.1 1 1 0 1 1 1 0 Membrane-associating domain DUF202 PF02656.15 KIR66739.1 - 0.37 11.3 12.6 0.2 12.1 2.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GTA_holin_3TM PF11351.8 KIR66739.1 - 0.73 10.4 4.9 0.52 10.9 2.2 2.1 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release Intg_mem_TP0381 PF09529.10 KIR66739.1 - 2.1 7.8 5.6 33 3.9 5.8 2.1 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) ODV-E18 PF10717.9 KIR66739.1 - 4.2 7.3 6.3 6.6 6.7 0.5 2.6 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF1345 PF07077.11 KIR66739.1 - 4.6 6.9 8.0 4.9 6.8 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4231 PF14015.6 KIR66739.1 - 6.7 7.2 7.5 5.5 7.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1772 PF08592.11 KIR66739.1 - 6.9 7.0 12.5 2.6 8.3 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) GGDEF PF00990.21 KIR66740.1 - 9.9e-45 152.2 0.0 1.8e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 KIR66740.1 - 2.2e-16 60.0 2.2 2.2e-16 60.0 2.2 2.9 4 0 0 4 4 4 1 HAMP domain GAF PF01590.26 KIR66740.1 - 5.2e-09 36.8 0.3 1.6e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 KIR66740.1 - 1e-08 35.6 9.9 4.1e-05 23.9 0.8 3.5 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 KIR66740.1 - 0.00027 21.3 3.5 0.0089 16.4 0.0 3.7 4 1 0 4 4 4 1 GAF domain Acetyltransf_3 PF13302.7 KIR66741.1 - 9.6e-18 65.2 0.0 1.6e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR66741.1 - 1.3e-07 31.8 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIR66741.1 - 0.0033 17.6 0.0 0.0077 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR66741.1 - 0.0048 16.8 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIR66741.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.19 KIR66743.1 - 6.5e-22 78.3 2.2 8.7e-22 77.8 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIR66743.1 - 8.2e-05 22.8 1.9 8.2e-05 22.8 1.9 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIR66743.1 - 0.003 16.8 0.1 0.024 13.9 0.6 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR66743.1 - 0.0031 18.0 0.2 0.013 16.1 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIR66743.1 - 0.012 14.9 0.5 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 KIR66743.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 KIR66743.1 - 0.07 12.0 1.6 9.1 5.0 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KIR66743.1 - 0.082 12.2 1.8 0.15 11.3 1.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1269 PF06897.12 KIR66743.1 - 0.22 11.8 1.0 0.47 10.8 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) GIDA PF01134.22 KIR66743.1 - 0.59 9.2 3.1 0.8 8.7 3.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A VWA_2 PF13519.6 KIR66744.1 - 1.7e-11 44.7 0.1 5.4e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIR66744.1 - 1.9e-09 38.0 0.0 2.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIR66744.1 - 1.2e-08 35.0 0.0 3.4e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1194 PF06707.11 KIR66744.1 - 0.00052 19.3 0.0 0.00084 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 KIR66744.1 - 0.18 11.1 1.1 16 4.8 0.1 3.0 3 1 1 4 4 4 0 VWA domain containing CoxE-like protein DUF3040 PF11239.8 KIR66745.1 - 7 7.0 7.7 5.3 7.4 1.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) TatD_DNase PF01026.21 KIR66746.1 - 2e-61 207.6 0.0 2.4e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase RrnaAD PF00398.20 KIR66747.1 - 6.4e-40 136.9 0.0 8.4e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIR66747.1 - 0.072 13.8 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TetR_N PF00440.23 KIR66748.1 - 7.8e-17 60.8 0.2 2.4e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 KIR66748.1 - 0.02 15.2 0.1 0.048 13.9 0.1 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 KIR66749.1 - 3.3e-07 29.9 6.4 5.4e-06 26.0 0.2 3.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_IclR PF09339.10 KIR66749.1 - 2.6e-05 23.9 0.4 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_38 PF13936.6 KIR66749.1 - 3.4e-05 23.5 0.0 0.00016 21.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 KIR66749.1 - 5.3e-05 23.2 2.7 9.1e-05 22.4 0.3 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.7 KIR66749.1 - 0.00026 21.1 0.1 0.016 15.4 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR66749.1 - 0.0026 17.6 1.7 0.48 10.3 0.0 2.8 2 0 0 2 2 2 1 MarR family HTH_7 PF02796.15 KIR66749.1 - 0.0027 17.7 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase TetR_N PF00440.23 KIR66749.1 - 0.0042 16.8 0.4 0.33 10.8 0.0 2.9 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family Terminase_5 PF06056.12 KIR66749.1 - 0.0069 16.3 1.1 0.017 15.0 0.2 2.3 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 KIR66749.1 - 0.0087 16.2 9.1 0.0094 16.1 0.2 4.2 4 0 0 4 4 4 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIR66749.1 - 0.011 15.4 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 TrmB PF01978.19 KIR66749.1 - 0.019 14.8 0.0 7 6.6 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.22 KIR66749.1 - 0.027 14.5 0.0 15 5.7 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix HTH_Tnp_4 PF13613.6 KIR66749.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Hexapep PF00132.24 KIR66750.1 - 1.1e-16 59.8 2.2 0.00026 20.6 0.0 5.5 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KIR66750.1 - 5.1e-15 56.2 13.1 5.7e-15 56.0 11.1 2.3 1 1 1 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KIR66750.1 - 2.9e-14 53.3 0.0 4.1e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 KIR66750.1 - 1.7e-06 27.9 2.1 2.8e-06 27.3 2.1 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 KIR66750.1 - 0.0012 18.6 9.9 0.014 15.1 0.1 4.3 5 0 0 5 5 5 1 Hexapeptide repeat of succinyl-transferase DUF2064 PF09837.9 KIR66750.1 - 0.0035 17.2 0.8 0.0081 16.0 0.8 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) CTP_transf_3 PF02348.19 KIR66750.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase CofC PF01983.16 KIR66750.1 - 0.08 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Guanylyl transferase CofC like DHquinase_II PF01220.19 KIR66750.1 - 0.15 11.7 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Dehydroquinase class II GTP_EFTU PF00009.27 KIR66751.1 - 1.4e-40 138.9 0.0 1.7e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIR66751.1 - 1.7e-06 28.1 0.0 1.3e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIR66751.1 - 7.3e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Lipase_GDSL_2 PF13472.6 KIR66753.1 - 4.9e-13 49.9 2.9 1.6e-12 48.2 2.9 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR66753.1 - 7.1e-06 26.1 0.0 2.6e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SLT PF01464.20 KIR66753.1 - 0.0059 16.2 0.3 0.017 14.7 0.3 1.8 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF3480 PF11979.8 KIR66753.1 - 0.3 10.0 0.0 0.45 9.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) Methyltransf_25 PF13649.6 KIR66754.1 - 2.6e-05 24.9 0.0 7.6e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR66754.1 - 0.0015 19.2 0.1 0.0098 16.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66754.1 - 0.0025 18.5 0.0 0.007 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR66754.1 - 0.15 11.8 0.0 1.2 9.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 KIR66754.1 - 0.23 10.6 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_4 PF02390.17 KIR66754.1 - 0.26 10.8 0.0 1.3 8.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DUF742 PF05331.11 KIR66755.1 - 2.8e-30 104.5 1.3 3.2e-30 104.3 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Sigma70_r4 PF04545.16 KIR66755.1 - 0.0029 17.1 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 MarR_2 PF12802.7 KIR66755.1 - 0.015 15.1 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KIR66755.1 - 0.028 14.7 0.1 0.16 12.3 0.0 2.2 3 0 0 3 3 3 0 Transcriptional regulator Aldedh PF00171.22 KIR66756.1 - 2.2e-161 537.5 0.0 2.5e-161 537.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MaoC_dehydratas PF01575.19 KIR66758.1 - 1.4e-14 53.7 0.0 1.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIR66758.1 - 0.03 14.4 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase DUF1834 PF08873.11 KIR66758.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) FAD_binding_3 PF01494.19 KIR66759.1 - 7.1e-15 55.1 3.4 3.2e-12 46.4 1.2 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIR66759.1 - 3.2e-09 36.9 15.2 5.6e-05 22.9 2.7 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIR66759.1 - 9.1e-08 31.9 3.3 1.8e-07 30.9 3.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR66759.1 - 4.3e-07 29.5 0.4 7.6e-07 28.6 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR66759.1 - 1.6e-06 27.5 1.6 2.3e-06 27.0 1.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIR66759.1 - 4e-06 25.8 0.4 6.5e-06 25.1 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KIR66759.1 - 2.2e-05 24.6 0.3 2.2e-05 24.6 0.3 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIR66759.1 - 6e-05 22.3 3.6 6e-05 22.3 3.6 2.2 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KIR66759.1 - 0.00057 19.0 6.8 0.007 15.5 6.8 2.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KIR66759.1 - 0.00072 20.1 0.4 0.0027 18.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIR66759.1 - 0.0024 17.2 0.1 0.0036 16.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIR66759.1 - 0.0062 15.9 0.8 0.011 15.1 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KIR66759.1 - 0.02 13.7 0.2 0.11 11.4 0.4 1.9 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KIR66759.1 - 0.029 14.3 0.3 0.056 13.3 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KIR66759.1 - 0.03 13.6 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DMT_YdcZ PF04657.13 KIR66760.1 - 1.9e-42 144.8 43.6 2e-24 86.4 16.7 2.0 2 0 0 2 2 2 2 Putative inner membrane exporter, YdcZ Leu_leader PF08054.11 KIR66760.1 - 0.37 10.4 3.9 3.6 7.2 0.1 2.8 2 0 0 2 2 2 0 Leucine operon leader peptide DUF4245 PF14030.6 KIR66761.1 - 7.9e-43 146.3 0.1 9.7e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) SAP130_C PF16014.5 KIR66762.1 - 0.049 12.7 0.4 0.058 12.5 0.4 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DivIC PF04977.15 KIR66763.1 - 4.8e-14 51.9 0.8 6.6e-14 51.4 0.8 1.2 1 0 0 1 1 1 1 Septum formation initiator RskA PF10099.9 KIR66763.1 - 7.2 6.9 19.8 0.57 10.4 14.5 1.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF501 PF04417.12 KIR66764.1 - 1.1e-38 132.1 0.6 5.3e-38 130.0 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF501) DUF58 PF01882.18 KIR66766.1 - 1.5e-14 54.1 0.2 3.7e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF58 Phage_Coat_B PF05356.11 KIR66767.1 - 0.024 14.5 2.8 0.62 10.0 0.6 2.6 1 1 1 2 2 2 0 Phage Coat protein B Lipase_GDSL_2 PF13472.6 KIR66768.1 - 5.9e-22 78.9 1.1 7.5e-22 78.6 1.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIR66768.1 - 2.3e-09 37.5 0.0 3.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1232 PF06803.12 KIR66769.1 - 2.1e-10 40.2 1.8 2.1e-10 40.2 1.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) DUF397 PF04149.12 KIR66770.1 - 2.7e-21 75.3 0.1 3.1e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF397) PKD PF00801.20 KIR66771.1 - 6.2e-13 48.4 3.9 6.2e-13 48.4 3.9 3.7 3 0 0 3 3 3 1 PKD domain Laminin_G_3 PF13385.6 KIR66771.1 - 2.9e-12 47.0 0.6 2.9e-12 47.0 0.6 3.3 4 1 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 KIR66771.1 - 3.1e-10 40.7 0.0 5.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 KIR66771.1 - 1e-06 29.0 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain DUF5011 PF16403.5 KIR66771.1 - 0.0081 16.3 2.7 0.017 15.2 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5011) DUF4625 PF15418.6 KIR66771.1 - 0.22 11.8 0.0 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) EAL PF00563.20 KIR66773.1 - 4.2e-68 229.4 0.0 7.1e-68 228.7 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR66773.1 - 1.5e-41 141.9 0.0 2.6e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PI-PLC-C1 PF16670.5 KIR66774.1 - 2.2e-09 36.8 0.0 1e-07 31.3 0.0 2.5 1 1 1 2 2 2 2 Phosphoinositide phospholipase C, Ca2+-dependent NTP_transferase PF00483.23 KIR66775.1 - 6.9e-41 140.5 0.0 1e-40 139.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 KIR66775.1 - 1.2e-07 31.7 0.4 2.2e-07 30.9 0.2 1.5 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase NTP_transf_3 PF12804.7 KIR66775.1 - 8.3e-07 29.5 10.2 7.2e-06 26.4 10.2 2.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KIR66775.1 - 0.002 17.9 0.3 0.0036 17.1 0.0 1.5 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NUDIX PF00293.28 KIR66776.1 - 3.5e-12 46.5 0.0 5.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4185 PF13810.6 KIR66777.1 - 0.022 14.0 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) DUF397 PF04149.12 KIR66778.1 - 9.6e-21 73.6 0.3 1.1e-20 73.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) ABC_tran PF00005.27 KIR66779.1 - 3.7e-33 114.9 0.0 6.2e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 KIR66779.1 - 1.1e-14 54.3 0.5 3.6e-14 52.7 0.5 1.9 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 KIR66779.1 - 0.00085 19.2 0.2 1.1 9.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR66779.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KIR66779.1 - 0.015 15.5 1.0 0.12 12.6 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 KIR66779.1 - 0.051 13.1 0.3 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIR66779.1 - 0.058 13.7 0.5 0.14 12.4 0.5 1.8 1 1 0 1 1 1 0 AAA domain OB_MalK PF17912.1 KIR66779.1 - 0.093 13.6 0.0 0.32 11.9 0.0 2.0 1 0 0 1 1 1 0 MalK OB fold domain G-alpha PF00503.20 KIR66779.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SRP54 PF00448.22 KIR66779.1 - 0.15 11.7 0.2 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CysA_C_terminal PF17850.1 KIR66779.1 - 0.22 12.1 2.1 0.64 10.6 0.5 2.6 2 0 0 2 2 2 0 CysA C-terminal regulatory domain SUKH-3 PF14433.6 KIR66780.1 - 2.2e-35 122.2 0.0 9e-35 120.2 0.0 1.9 2 0 0 2 2 2 1 SUKH-3 immunity protein YwqJ-deaminase PF14431.6 KIR66780.1 - 3e-21 76.0 0.0 4.5e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 YwqJ-like deaminase Sucrose_synth PF00862.19 KIR66780.1 - 0.24 9.7 0.0 0.67 8.2 0.0 1.6 2 0 0 2 2 2 0 Sucrose synthase Radical_SAM PF04055.21 KIR66781.1 - 8.9e-16 58.7 0.1 1.6e-15 57.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KIR66781.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 KIR66781.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain HTH_31 PF13560.6 KIR66782.1 - 3.9e-14 52.7 15.8 1.6e-08 34.8 6.1 3.1 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 KIR66782.1 - 2e-09 37.3 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.7 KIR66782.1 - 1.8e-07 31.1 0.0 0.025 14.6 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_38 PF13936.6 KIR66782.1 - 0.00018 21.2 0.4 0.11 12.3 0.3 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 KIR66782.1 - 0.00069 19.3 1.1 0.17 11.7 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_37 PF13744.6 KIR66782.1 - 0.0013 18.6 0.1 0.0094 15.9 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR66782.1 - 0.0042 17.0 0.3 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR66782.1 - 0.005 16.2 1.9 0.0062 15.9 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 KIR66782.1 - 0.006 16.6 1.2 0.1 12.7 0.6 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_25 PF13413.6 KIR66782.1 - 0.016 15.1 0.2 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain AP_endonuc_2 PF01261.24 KIR66782.1 - 0.023 14.1 2.0 0.081 12.3 2.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel HTH_28 PF13518.6 KIR66782.1 - 0.091 12.9 0.0 0.091 12.9 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain Crp PF00325.20 KIR66782.1 - 0.099 12.3 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DDE_Tnp_4 PF13359.6 KIR66783.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR66783.1 - 4.7e-15 55.0 0.0 9.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR66783.1 - 3.7e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR66783.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_38 PF13936.6 KIR66783.1 - 0.06 13.1 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIR66783.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DEAD PF00270.29 KIR66784.1 - 3e-06 27.1 0.0 0.00032 20.5 0.0 2.4 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR66784.1 - 5.7e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIR66784.1 - 0.00016 21.9 0.1 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KIR66784.1 - 0.0056 16.7 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEC-1_N PF04625.13 KIR66785.1 - 0.088 11.8 2.0 0.1 11.6 2.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CBM_2 PF00553.19 KIR66786.1 - 5.9e-35 119.6 8.6 5.9e-35 119.6 8.6 2.5 3 0 0 3 3 3 1 Cellulose binding domain fn3 PF00041.21 KIR66786.1 - 1.2e-16 60.8 5.4 1.4e-08 34.9 0.1 3.1 2 1 0 2 2 2 2 Fibronectin type III domain CBM49 PF09478.10 KIR66786.1 - 0.0022 18.2 0.1 0.0055 17.0 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 fn3_2 PF16893.5 KIR66786.1 - 0.19 11.9 3.0 15 5.8 0.1 2.7 2 1 0 3 3 3 0 Fibronectin type III domain PG_binding_1 PF01471.18 KIR66787.1 - 3.6e-12 46.3 0.0 1.2e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 KIR66787.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain UbiA PF01040.18 KIR66788.1 - 4.2e-21 75.4 23.0 4.2e-21 75.4 23.0 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Cytochrom_B558a PF05038.13 KIR66788.1 - 0.26 10.8 2.1 0.66 9.5 0.1 2.3 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Epimerase PF01370.21 KIR66789.1 - 2.2e-33 115.7 0.0 2.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIR66789.1 - 2.5e-22 79.7 0.0 8.8e-22 77.9 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIR66789.1 - 5.8e-22 78.0 0.0 7.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIR66789.1 - 4e-15 56.2 0.2 4e-15 56.2 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIR66789.1 - 2.7e-09 36.6 1.2 1.2e-05 24.6 0.0 3.3 2 1 0 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 KIR66789.1 - 4.3e-09 35.9 0.1 5.7e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KIR66789.1 - 5.9e-09 35.8 0.0 9.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KIR66789.1 - 0.00031 20.0 3.0 0.01 15.0 3.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KIR66789.1 - 0.002 17.6 1.4 0.018 14.5 1.4 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIR66789.1 - 0.35 10.8 2.1 1.2 9.0 2.0 2.0 1 1 0 1 1 1 0 KR domain UbiA PF01040.18 KIR66790.1 - 6.7e-29 100.9 25.1 8.4e-29 100.6 25.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Endonuclease_5 PF04493.14 KIR66791.1 - 2.1e-65 220.1 0.0 2.6e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V PadR PF03551.14 KIR66792.1 - 3e-06 27.1 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 KIR66792.1 - 9.4e-06 26.2 0.2 1.8e-05 25.3 0.1 1.5 2 0 0 2 2 2 1 Virulence activator alpha C-term HTH_20 PF12840.7 KIR66792.1 - 2.2e-05 24.4 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AphA_like PF14557.6 KIR66792.1 - 2.7e-05 23.9 0.0 3.5e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator DUF4456 PF14644.6 KIR66792.1 - 0.0029 17.3 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) HTH_Crp_2 PF13545.6 KIR66792.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF2524 PF10732.9 KIR66792.1 - 0.082 13.2 0.4 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) HTH_5 PF01022.20 KIR66792.1 - 0.13 12.2 0.0 2 8.4 0.0 2.2 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF4880 PF16220.5 KIR66792.1 - 0.49 10.3 0.1 0.49 10.3 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4880) DUF179 PF02622.15 KIR66793.1 - 4.1e-38 130.8 0.0 5.2e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 FA_desaturase PF00487.24 KIR66794.1 - 8e-09 35.7 22.2 8e-09 35.7 22.2 2.7 1 1 1 3 3 3 3 Fatty acid desaturase SNF2_N PF00176.23 KIR66795.1 - 3.4e-30 105.0 0.1 2.4e-29 102.1 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIR66795.1 - 2.2e-13 50.5 0.0 1.1e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIR66795.1 - 2.5e-07 30.6 0.0 2.8e-06 27.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 KIR66795.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KIR66795.1 - 0.0013 18.7 0.9 0.22 11.5 0.1 3.1 3 0 0 3 3 3 1 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 KIR66795.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF1414 PF07208.11 KIR66795.1 - 0.022 14.8 0.1 0.072 13.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) AAA_22 PF13401.6 KIR66795.1 - 0.041 14.1 0.1 0.53 10.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain MbtH PF03621.13 KIR66796.1 - 2.4e-26 91.0 0.1 3e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein LPMO_10 PF03067.15 KIR66797.1 - 4.6e-34 118.8 0.0 6e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF347 PF03988.12 KIR66797.1 - 0.029 14.5 1.5 0.068 13.4 1.5 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) HTH_31 PF13560.6 KIR66798.1 - 1.5e-12 47.7 1.0 1.5e-12 47.7 1.0 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66798.1 - 5.1e-08 32.8 0.0 9.9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR66798.1 - 2.1e-05 24.4 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 KIR66798.1 - 0.026 14.4 0.2 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_S24 PF00717.23 KIR66799.1 - 9.8e-11 41.5 0.0 2.3e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIR66799.1 - 1.8e-05 24.6 0.1 0.057 13.2 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DJ-1_PfpI PF01965.24 KIR66800.1 - 1.7e-23 83.2 0.1 2.6e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 KIR66800.1 - 5.3e-21 74.7 3.6 8.8e-21 74.0 3.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KIR66800.1 - 2.6e-18 65.6 0.0 1.8e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 KIR66800.1 - 0.00054 19.7 1.6 0.0036 17.1 0.1 2.8 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family EAL PF00563.20 KIR66801.1 - 5.2e-74 248.8 0.0 7.7e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR66801.1 - 1.1e-38 132.5 0.0 1.8e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 KIR66801.1 - 0.018 15.3 0.7 0.018 15.3 0.7 3.3 2 2 1 3 3 3 0 GGDEF-like domain TilS_C PF11734.8 KIR66801.1 - 0.91 9.0 2.8 2.3 7.7 2.8 1.6 1 0 0 1 1 1 0 TilS substrate C-terminal domain DNA_methylase PF00145.17 KIR66802.1 - 6e-56 190.2 0.0 8.5e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 KIR66802.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KIR66802.1 - 0.081 13.6 0.1 0.2 12.4 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain EndIII_4Fe-2S PF10576.9 KIR66802.1 - 4.7 7.7 7.0 8.3 6.9 7.0 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III NAD_binding_1 PF00175.21 KIR66803.1 - 1.8e-15 57.5 0.0 3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIR66803.1 - 9.4e-09 35.5 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4648 PF15505.6 KIR66803.1 - 0.045 14.6 0.1 0.13 13.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) Response_reg PF00072.24 KIR66804.1 - 3.2e-25 88.5 0.0 4.7e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 KIR66804.1 - 5e-15 54.8 0.3 8.6e-15 54.0 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR66804.1 - 1.1e-05 25.0 1.7 1.1e-05 25.0 1.7 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66804.1 - 7.6e-05 22.2 0.4 0.00015 21.2 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KIR66804.1 - 0.001 18.6 0.0 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KIR66804.1 - 0.0097 15.7 0.4 0.032 14.0 0.4 1.9 1 0 0 1 1 1 1 Homeodomain-like domain Amidohydro_1 PF01979.20 KIR66807.1 - 1.8e-23 83.4 0.1 1.7e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIR66807.1 - 6.9e-20 72.0 12.7 2.1e-12 47.3 6.4 2.6 1 1 1 2 2 2 2 Amidohydrolase family Glycos_transf_2 PF00535.26 KIR66808.1 - 1.9e-13 50.6 0.0 2.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66808.1 - 5.8e-09 36.2 0.9 1.4e-08 34.9 0.9 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIR66808.1 - 0.0047 16.4 0.1 0.013 14.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KIR66808.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_hydro_10 PF00331.20 KIR66809.1 - 4.8e-102 341.3 0.0 5.5e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KIR66809.1 - 0.0075 15.7 0.8 0.02 14.2 0.5 1.7 1 1 1 2 2 2 1 Beta-galactosidase Glyco_hydro_1 PF00232.18 KIR66809.1 - 0.065 11.6 0.1 1.4 7.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 1 LytR_cpsA_psr PF03816.14 KIR66810.1 - 4.6e-46 156.7 0.0 6.4e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain CopC PF04234.12 KIR66812.1 - 2.6e-22 79.7 0.1 6.3e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 CopC domain CopD PF05425.13 KIR66812.1 - 1.9e-15 57.2 17.1 1.9e-15 57.2 17.1 3.6 3 1 0 3 3 3 1 Copper resistance protein D Big_5 PF13205.6 KIR66812.1 - 0.0073 17.0 1.7 0.023 15.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial Ig-like domain DUF1420 PF07220.11 KIR66812.1 - 0.025 13.2 0.5 0.035 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1420) ETF_alpha PF00766.19 KIR66814.1 - 5.7e-37 125.6 2.0 1.1e-36 124.7 0.6 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 KIR66814.1 - 4.2e-32 111.5 12.1 6.7e-32 110.8 12.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DNA_ligase_aden PF01653.18 KIR66815.1 - 1.3e-119 399.0 0.0 1.6e-119 398.7 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 KIR66815.1 - 3.6e-31 106.9 1.3 7.5e-31 105.9 1.3 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 KIR66815.1 - 4e-24 84.5 0.0 8.7e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif BRCT PF00533.26 KIR66815.1 - 3.9e-11 43.2 0.0 6.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 KIR66815.1 - 5.8e-10 39.6 0.0 7e-08 33.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_ligase_ZBD PF03119.16 KIR66815.1 - 3.3e-07 30.2 4.8 3.3e-07 30.2 4.8 2.1 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain HHH PF00633.23 KIR66815.1 - 4.3e-05 23.2 0.4 0.00012 21.8 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 KIR66815.1 - 5.3e-05 23.1 0.0 0.00019 21.3 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain HHH_8 PF14716.6 KIR66815.1 - 0.013 15.8 0.0 0.05 14.0 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_3 PF12836.7 KIR66815.1 - 0.018 15.3 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif EHD_N PF16880.5 KIR66815.1 - 0.13 12.1 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 N-terminal EH-domain containing protein Glu-tRNAGln PF02686.15 KIR66816.1 - 2e-16 60.0 0.1 2.9e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Transketolase_N PF00456.21 KIR66817.1 - 3.2e-19 69.1 0.0 4e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain PDH_E1_M PF17831.1 KIR66817.1 - 8.7e-13 48.3 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_C PF02780.20 KIR66817.1 - 5.9e-06 26.2 0.4 1.8e-05 24.6 0.4 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIR66817.1 - 0.00026 20.3 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase EAL PF00563.20 KIR66818.1 - 1.1e-50 172.5 0.0 1.6e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR66818.1 - 4.8e-23 81.7 0.0 7.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 KIR66818.1 - 4e-13 49.6 1.2 1.1e-12 48.2 1.2 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KIR66818.1 - 6e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KIR66818.1 - 0.00013 22.2 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KIR66818.1 - 0.002 18.4 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_10 PF13596.6 KIR66818.1 - 0.015 15.9 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 KIR66818.1 - 0.048 13.7 0.4 0.21 11.7 0.1 2.4 2 0 0 2 2 2 0 PAS domain BPD_transp_1 PF00528.22 KIR66819.1 - 3.5e-16 59.5 17.3 3.5e-16 59.5 17.3 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component NiFe_hyd_3_EhaA PF17367.2 KIR66819.1 - 7.7 6.7 9.6 1.9 8.7 4.0 2.8 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A FAD_oxidored PF12831.7 KIR66820.1 - 1.3e-125 420.1 1.6 1.6e-125 419.9 1.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIR66820.1 - 0.14 10.8 1.6 0.22 10.2 1.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KIR66820.1 - 0.16 11.2 1.5 5.9 6.1 1.2 3.2 4 0 0 4 4 4 0 Thi4 family EAL PF00563.20 KIR66821.1 - 3.8e-67 226.3 0.0 5.6e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR66821.1 - 1.8e-38 131.8 0.0 3.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Y_phosphatase3 PF13350.6 KIR66822.1 - 2.8e-62 210.7 0.0 3.2e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIR66822.1 - 0.00028 20.5 0.0 0.00033 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KIR66822.1 - 0.0034 17.0 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 KIR66822.1 - 0.023 13.6 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 KIR66822.1 - 0.034 14.0 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF3950 PF13132.6 KIR66822.1 - 0.043 13.6 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Exo_endo_phos PF03372.23 KIR66823.1 - 1.9e-09 37.4 3.9 3.5e-09 36.5 3.9 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_Gly3P_dh_C PF07479.14 KIR66824.1 - 5.5e-49 166.1 0.2 8.1e-49 165.6 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KIR66824.1 - 9.4e-49 165.4 0.0 1.6e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KIR66824.1 - 6.6e-10 39.4 0.0 2.3e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIR66824.1 - 1.7e-08 34.2 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KIR66824.1 - 3.9e-05 23.9 0.0 0.00019 21.6 0.0 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIR66824.1 - 0.00087 18.9 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KIR66824.1 - 0.0018 18.2 0.1 0.0046 16.9 0.1 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KIR66824.1 - 0.0022 18.5 0.2 0.024 15.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIR66824.1 - 0.0042 17.5 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIR66824.1 - 0.0044 16.3 0.3 0.094 11.9 0.0 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KIR66824.1 - 0.0057 16.5 0.9 0.036 13.9 0.2 2.7 2 1 1 3 3 3 1 Rossmann-like domain NAD_binding_8 PF13450.6 KIR66824.1 - 0.026 14.7 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KIR66824.1 - 0.035 14.4 0.0 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KIR66824.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIR66824.1 - 0.076 13.1 0.0 0.24 11.5 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PDH PF02153.17 KIR66824.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Cys_Met_Meta_PP PF01053.20 KIR66825.1 - 5.2e-75 252.4 0.0 1.7e-74 250.6 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIR66825.1 - 0.00084 18.4 0.0 0.0024 16.9 0.0 1.7 3 0 0 3 3 3 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KIR66825.1 - 0.089 11.3 0.0 2 6.8 0.0 2.0 2 0 0 2 2 2 0 Methionine gamma-lyase MTS PF05175.14 KIR66826.1 - 3.2e-11 43.1 0.0 9.7e-11 41.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIR66826.1 - 1.7e-07 31.8 0.0 5.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR66826.1 - 2.1e-07 30.9 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIR66826.1 - 4e-07 29.7 0.0 2.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 KIR66826.1 - 0.00022 21.7 1.8 0.036 14.6 0.1 2.8 1 1 1 2 2 2 1 PrmC N-terminal domain Methyltransf_11 PF08241.12 KIR66826.1 - 0.00048 20.7 0.0 0.0036 17.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 KIR66826.1 - 0.0018 17.8 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Cons_hypoth95 PF03602.15 KIR66826.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KIR66826.1 - 0.0038 17.1 0.0 0.0093 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KIR66826.1 - 0.031 14.0 0.1 0.11 12.2 0.1 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FtsJ PF01728.19 KIR66826.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CutC PF03932.14 KIR66826.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 CutC family Met_10 PF02475.16 KIR66826.1 - 0.19 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.12 KIR66826.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_15 PF09445.10 KIR66826.1 - 0.3 10.6 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FA_synthesis PF02504.15 KIR66827.1 - 4.3e-65 219.9 4.4 7.8e-61 205.9 1.2 2.0 2 0 0 2 2 2 2 Fatty acid synthesis protein PTA_PTB PF01515.19 KIR66827.1 - 0.0035 16.7 0.1 0.0049 16.2 0.1 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase NUDIX PF00293.28 KIR66828.1 - 1e-20 74.1 0.6 1.3e-20 73.8 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain AAA_lid_3 PF17862.1 KIR66828.1 - 0.027 14.3 0.0 0.095 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA+ lid domain Peptidase_M23 PF01551.22 KIR66829.1 - 1.6e-11 44.3 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M23 DUF4081 PF13312.6 KIR66830.1 - 3.5e-36 123.6 0.1 7e-36 122.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4081) Acetyltransf_1 PF00583.25 KIR66830.1 - 5.7e-12 45.9 0.1 1.1e-11 44.9 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIR66830.1 - 4.1e-08 33.5 0.0 8.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIR66830.1 - 9.4e-08 32.1 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR66830.1 - 9.1e-07 28.8 0.0 2.6e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIR66830.1 - 9.3e-07 29.6 0.0 1.7e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIR66830.1 - 0.0016 18.5 0.1 0.0037 17.3 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR66830.1 - 0.0086 15.8 0.5 0.052 13.2 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIR66830.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase SDF PF00375.18 KIR66831.1 - 2.2e-111 372.6 31.7 2.5e-111 372.5 31.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Methyltransf_19 PF04672.12 KIR66832.1 - 1.3e-91 306.8 0.2 1.5e-91 306.6 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_12 PF08242.12 KIR66832.1 - 0.00037 21.2 0.0 0.00071 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIR66832.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KIR66832.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIR66832.1 - 0.052 14.2 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain EAL PF00563.20 KIR66833.1 - 3.7e-63 213.2 0.0 3.9e-61 206.6 0.0 2.5 1 1 0 1 1 1 1 EAL domain GGDEF PF00990.21 KIR66833.1 - 2.4e-44 150.9 0.0 1.6e-43 148.3 0.0 2.2 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 KIR66833.1 - 3.1e-15 56.2 0.0 5.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KIR66833.1 - 1.5e-14 54.1 0.0 3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KIR66833.1 - 3.5e-11 43.1 0.0 7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KIR66833.1 - 7.3e-11 42.3 0.1 7.3e-11 42.3 0.1 3.6 3 1 1 4 4 4 1 PAS fold PAS_8 PF13188.7 KIR66833.1 - 2.9e-07 30.4 0.3 1.7e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 PAS domain Guanylate_cyc PF00211.20 KIR66833.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Aldedh PF00171.22 KIR66834.1 - 6.1e-157 522.8 0.0 6.9e-157 522.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3022 PF11226.8 KIR66834.1 - 0.027 14.9 2.0 0.049 14.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) DUF5133 PF17196.4 KIR66834.1 - 3.8 7.8 6.1 36 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF5133) STAS_2 PF13466.6 KIR66835.1 - 2.9e-10 40.3 3.6 4.3e-10 39.8 3.6 1.3 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 KIR66835.1 - 6.2e-05 22.6 0.0 9.3e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 STAS domain ABC_tran PF00005.27 KIR66836.1 - 1.1e-32 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KIR66836.1 - 0.00028 20.5 0.2 0.00059 19.5 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KIR66836.1 - 0.00035 20.3 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein SMC_N PF02463.19 KIR66836.1 - 0.00037 20.0 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIR66836.1 - 0.0088 16.3 0.6 0.072 13.4 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR66836.1 - 0.013 15.9 5.5 0.034 14.5 5.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KIR66836.1 - 0.02 14.5 2.0 0.13 11.9 0.3 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIR66836.1 - 0.035 14.0 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KIR66836.1 - 0.1 12.7 2.2 0.33 11.1 0.7 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIR66836.1 - 0.14 11.9 4.4 0.46 10.2 4.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIR66836.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2383 PF09537.10 KIR66837.1 - 0.094 13.1 0.2 11 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) RBFA PF02033.18 KIR66838.1 - 1.7e-26 92.7 0.1 2.1e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A CsbD PF05532.12 KIR66838.1 - 0.0099 15.8 1.2 2.6 8.0 0.4 2.8 2 0 0 2 2 2 2 CsbD-like DUF948 PF06103.11 KIR66838.1 - 0.047 13.9 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DapB_C PF05173.14 KIR66839.1 - 5.4e-31 107.1 0.0 7.7e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 KIR66839.1 - 5.5e-28 97.6 0.3 1.7e-26 92.8 0.3 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KIR66839.1 - 0.0019 18.6 0.1 0.16 12.4 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KIR66839.1 - 0.081 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KIR66839.1 - 0.12 12.6 0.7 2.6 8.3 0.1 2.4 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3156 PF11354.8 KIR66839.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) Sigma70_r2 PF04542.14 KIR66840.1 - 1.4e-20 72.8 0.5 1.4e-20 72.8 0.5 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR66840.1 - 2.3e-13 49.6 0.1 2.3e-13 49.6 0.1 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 SnoaL_2 PF12680.7 KIR66840.1 - 1.1e-06 29.2 1.0 8.6e-06 26.3 0.1 2.7 3 0 0 3 3 3 1 SnoaL-like domain Sigma70_r4 PF04545.16 KIR66840.1 - 0.00014 21.3 1.2 0.00018 20.9 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 DUF4754 PF15946.5 KIR66840.1 - 0.015 15.6 0.6 0.97 9.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) Thy1 PF02511.15 KIR66841.1 - 6.6e-54 182.6 1.2 8e-54 182.3 1.2 1.0 1 0 0 1 1 1 1 Thymidylate synthase complementing protein CHASE3 PF05227.13 KIR66841.1 - 0.0093 15.9 1.2 0.015 15.2 1.2 1.2 1 0 0 1 1 1 1 CHASE3 domain fn3 PF00041.21 KIR66842.1 - 2.2e-07 31.1 1.8 0.0017 18.6 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain Cu-oxidase_2 PF07731.14 KIR66842.1 - 2.5e-07 30.5 0.1 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Pur_ac_phosph_N PF16656.5 KIR66842.1 - 2.2e-06 28.1 1.8 0.52 10.9 0.2 3.4 3 0 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KIR66842.1 - 0.00033 21.1 0.2 8.8 6.9 0.0 3.6 3 0 0 3 3 3 2 PhoD-like phosphatase, N-terminal domain Cys_rich_CPCC PF14206.6 KIR66843.1 - 1e-16 60.5 0.0 1.4e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich CPCC APH PF01636.23 KIR66844.1 - 1.7e-28 100.2 11.3 2.6e-28 99.6 11.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DEAD_assoc PF08494.11 KIR66845.1 - 2.8e-74 249.1 1.0 5.2e-74 248.2 1.0 1.5 1 0 0 1 1 1 1 DEAD/H associated DEAD PF00270.29 KIR66845.1 - 2.8e-23 82.6 0.0 4.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIR66845.1 - 8.5e-13 48.6 0.0 2.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIR66845.1 - 3.7e-05 23.8 0.0 6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KIR66845.1 - 0.0066 16.1 0.4 0.0066 16.1 0.4 2.6 2 0 0 2 2 2 1 AAA domain MNHE PF01899.16 KIR66846.1 - 6.5e-36 123.3 0.7 7.7e-36 123.0 0.7 1.1 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit PhaG_MnhG_YufB PF03334.14 KIR66847.1 - 5.5e-26 90.6 5.3 6.6e-26 90.4 5.3 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit BPD_transp_1 PF00528.22 KIR66848.1 - 2.5e-16 59.9 15.9 2.5e-16 59.9 15.9 1.6 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ECF_trnsprt PF12822.7 KIR66848.1 - 7.4 6.6 18.7 0.18 11.9 8.9 2.6 2 1 0 2 2 2 0 ECF transporter, substrate-specific component Radical_SAM PF04055.21 KIR66849.1 - 4.9e-30 105.1 0.0 8.3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KIR66849.1 - 7.1e-26 90.1 0.0 1.4e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 B12-binding PF02310.19 KIR66849.1 - 0.037 14.1 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain Spo0M PF07070.11 KIR66850.1 - 3e-83 278.5 0.1 3.5e-83 278.3 0.1 1.0 1 0 0 1 1 1 1 SpoOM protein MTS PF05175.14 KIR66851.1 - 4.7e-17 62.1 0.0 1.8e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIR66851.1 - 2.8e-09 37.6 0.0 6.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR66851.1 - 3.5e-07 30.8 0.0 7.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIR66851.1 - 7.2e-07 28.9 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KIR66851.1 - 1.2e-05 25.1 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66851.1 - 0.00076 20.2 0.0 0.0021 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 KIR66851.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 KIR66851.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CopG_antitoxin PF12441.8 KIR66852.1 - 0.00093 19.7 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system RHH_1 PF01402.21 KIR66852.1 - 0.0013 18.5 1.4 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family Sigma70_r3 PF04539.16 KIR66854.1 - 5.6e-29 100.1 1.8 2.1e-28 98.2 0.9 2.6 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 KIR66854.1 - 8.9e-23 79.9 0.3 2.2e-22 78.6 0.3 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 KIR66854.1 - 1e-20 73.0 4.1 1.7e-18 65.8 0.7 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 KIR66854.1 - 1.3e-17 63.5 0.2 5.7e-17 61.4 0.2 2.3 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r1_1 PF03979.14 KIR66854.1 - 0.0011 18.9 0.4 0.007 16.4 0.0 2.4 3 0 0 3 3 3 1 Sigma-70 factor, region 1.1 HTH_15 PF12324.8 KIR66854.1 - 0.028 14.4 1.4 0.74 9.8 0.0 3.6 3 1 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Rrf2 PF02082.20 KIR66854.1 - 0.042 14.2 1.0 0.5 10.7 0.1 3.1 3 1 1 4 4 4 0 Transcriptional regulator TRAM PF01938.20 KIR66855.1 - 9.1e-13 48.0 0.8 1.9e-12 47.0 0.8 1.5 1 0 0 1 1 1 1 TRAM domain tRNA_U5-meth_tr PF05958.11 KIR66855.1 - 1e-06 28.0 0.0 1.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 KIR66855.1 - 0.00031 20.4 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KIR66855.1 - 0.00033 20.4 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 KIR66855.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KIR66855.1 - 0.0066 17.1 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KIR66855.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltrans_SAM PF10672.9 KIR66855.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase YtpI PF14007.6 KIR66856.1 - 0.047 13.8 0.4 0.047 13.8 0.4 2.3 3 0 0 3 3 3 0 YtpI-like protein DUF2298 PF10060.9 KIR66856.1 - 0.48 9.1 26.1 1.4 7.6 3.3 2.8 1 1 1 2 2 2 0 Uncharacterized membrane protein (DUF2298) HATPase_c PF02518.26 KIR66857.1 - 1.1e-16 61.3 0.0 2.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR66857.1 - 2.3e-11 43.6 3.1 3.7e-11 42.9 0.6 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KIR66857.1 - 7.4e-11 42.3 0.5 2.4e-10 40.6 0.5 2.0 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 KIR66857.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 GHKL domain SCAB_CC PF16712.5 KIR66857.1 - 0.13 12.1 1.2 0.2 11.5 1.2 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Malectin PF11721.8 KIR66858.1 - 9.5e-18 64.8 0.0 1.6e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Malectin domain DUF5122 PF17164.4 KIR66858.1 - 0.00011 22.4 19.3 2.5 8.5 0.8 7.0 7 0 0 7 7 7 4 Domain of unknown function (DUF5122) beta-propeller Malectin_like PF12819.7 KIR66858.1 - 0.00012 21.4 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Malectin-like domain HTH_17 PF12728.7 KIR66859.1 - 0.11 12.6 0.2 0.31 11.3 0.2 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain FtsX PF02687.21 KIR66860.1 - 0.0056 17.1 1.4 0.0056 17.1 1.4 4.5 3 1 1 4 4 4 1 FtsX-like permease family TOBE_3 PF12857.7 KIR66860.1 - 0.023 14.6 4.4 0.11 12.5 0.0 3.6 3 0 0 3 3 3 0 TOBE-like domain ABC_tran PF00005.27 KIR66861.1 - 3.8e-31 108.4 0.0 4.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66861.1 - 4.8e-05 23.3 0.1 0.0073 16.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIR66861.1 - 0.00094 19.6 2.3 0.0021 18.4 2.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KIR66861.1 - 0.004 16.9 1.2 0.012 15.3 1.2 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIR66861.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KIR66861.1 - 0.084 13.2 0.2 0.76 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KIR66861.1 - 0.095 12.6 0.1 0.21 11.5 0.1 1.6 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KIR66861.1 - 0.13 11.6 0.0 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR66861.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIR66861.1 - 0.19 11.7 0.0 4.9 7.0 0.0 2.1 2 0 0 2 2 2 0 NTPase TerD PF02342.18 KIR66862.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 TerD domain DUF2478 PF10649.9 KIR66862.1 - 0.11 12.1 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) Peripla_BP_3 PF13377.6 KIR66863.1 - 2.8e-37 128.6 2.2 3.5e-37 128.3 0.6 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66863.1 - 3.4e-20 72.6 0.0 4.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR66863.1 - 2.1e-15 57.0 0.0 3.9e-15 56.1 0.0 1.4 2 0 0 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 KIR66863.1 - 5.6e-15 54.9 0.2 1.2e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 KIR66863.1 - 0.00074 19.8 3.0 0.0017 18.6 1.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66863.1 - 0.0098 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix TetR_N PF00440.23 KIR66863.1 - 0.14 11.9 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Glyco_hydro_62 PF03664.13 KIR66864.1 - 4.9e-151 501.6 16.6 8.2e-151 500.9 16.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_10 PF00331.20 KIR66864.1 - 2.7e-102 342.2 0.0 4.2e-102 341.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Ricin_B_lectin PF00652.22 KIR66864.1 - 6.7e-29 100.7 12.8 6.7e-29 100.7 12.8 2.4 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66864.1 - 1.5e-26 93.0 30.8 2e-12 47.6 3.1 4.1 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like ET PF01684.16 KIR66864.1 - 0.52 10.7 8.1 4.4 7.7 0.3 3.6 2 1 2 4 4 4 0 ET module Acetyltransf_3 PF13302.7 KIR66865.1 - 3.1e-14 53.8 0.0 3.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR66865.1 - 3.3e-13 49.6 0.5 4.7e-13 49.1 0.5 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIR66865.1 - 7.8e-11 42.2 0.0 9.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIR66865.1 - 3.3e-07 30.3 0.0 4.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIR66865.1 - 1.4e-06 28.5 0.0 1.8e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIR66865.1 - 5.2e-06 26.3 0.0 2.1e-05 24.4 0.0 1.9 1 1 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 KIR66865.1 - 1.7e-05 25.2 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIR66865.1 - 0.0055 16.9 2.2 0.0055 16.9 2.2 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Aminotran_1_2 PF00155.21 KIR66866.1 - 2.8e-60 204.4 0.0 3.1e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIR66866.1 - 4.6e-07 29.4 0.3 6.1e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIR66866.1 - 8.8e-05 21.2 0.0 0.00013 20.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIR66866.1 - 0.00031 20.2 2.5 0.0005 19.5 2.5 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KIR66866.1 - 0.0007 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 KIR66866.1 - 0.022 13.3 0.3 0.036 12.7 0.3 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase UTRA PF07702.13 KIR66866.1 - 0.063 13.1 0.4 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 UTRA domain AAA_26 PF13500.6 KIR66867.1 - 6e-30 104.6 0.0 7.3e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF1611 PF07755.11 KIR66867.1 - 7.1e-08 32.0 5.7 4.8e-05 22.7 4.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF1611_C) P-loop domain CbiA PF01656.23 KIR66867.1 - 2.9e-07 30.6 0.0 3.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 KIR66867.1 - 0.00043 20.2 0.1 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KIR66867.1 - 0.22 11.1 0.9 2.1 7.9 0.9 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_trans_4_4 PF13579.6 KIR66867.1 - 8.9 6.7 17.7 56 4.1 17.7 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Peripla_BP_3 PF13377.6 KIR66868.1 - 9.4e-32 110.6 1.1 2.3e-31 109.4 0.2 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66868.1 - 4.3e-19 69.0 0.0 5.1e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 KIR66868.1 - 7.8e-18 64.0 0.1 1.5e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR66868.1 - 3.1e-08 33.5 0.0 7.3e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_31 PF13560.6 KIR66868.1 - 0.0006 20.1 0.2 0.0067 16.7 0.0 2.9 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KIR66868.1 - 0.0086 15.5 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 KIR66868.1 - 0.016 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix SnoaL_2 PF12680.7 KIR66869.1 - 5.9e-18 65.4 0.8 7.5e-18 65.1 0.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KIR66869.1 - 3e-10 40.0 0.2 3.4e-07 30.1 0.1 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KIR66869.1 - 1.6e-07 31.7 0.2 2.7e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KIR66869.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain LEH PF07858.12 KIR66869.1 - 0.049 13.7 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain MLTR_LBD PF17765.1 KIR66870.1 - 2e-32 112.6 3.6 3.1e-32 112.0 3.6 1.3 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 KIR66870.1 - 1.1e-12 48.1 3.9 1.1e-12 48.1 3.9 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 KIR66870.1 - 2.4e-09 37.1 0.0 5.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIR66870.1 - 7e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Nitroreductase PF00881.24 KIR66871.1 - 4.2e-11 43.2 0.9 7.4e-06 26.1 0.5 3.5 3 1 0 3 3 3 2 Nitroreductase family TM1586_NiRdase PF14512.6 KIR66871.1 - 0.015 14.9 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Putative TM nitroreductase DAGK_cat PF00781.24 KIR66872.1 - 3.1e-17 62.4 0.4 4.7e-17 61.8 0.4 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KIR66872.1 - 0.0062 15.8 0.2 0.0091 15.2 0.2 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Spo0M PF07070.11 KIR66873.1 - 2e-80 269.3 0.0 2.5e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 SpoOM protein DUF2076 PF09849.9 KIR66873.1 - 1.4e-05 25.2 1.4 2e-05 24.8 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TraT PF05818.12 KIR66873.1 - 0.14 11.9 2.0 0.22 11.2 2.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein AAA_19 PF13245.6 KIR66875.1 - 5.1e-13 49.6 0.0 1e-11 45.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIR66875.1 - 3.5e-10 39.5 0.0 1.2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIR66875.1 - 2.1e-09 37.3 0.0 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KIR66875.1 - 5.5e-09 36.1 0.0 0.00013 21.8 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 KIR66875.1 - 2.5e-06 27.1 0.0 5.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KIR66875.1 - 1.3e-05 24.8 0.0 0.024 14.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 KIR66875.1 - 3.1e-05 23.8 5.1 0.026 14.2 0.3 3.7 4 0 0 4 4 4 2 AAA domain DUF2075 PF09848.9 KIR66875.1 - 0.0008 18.7 0.1 0.0044 16.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KIR66875.1 - 0.0038 17.0 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIR66875.1 - 0.0042 17.4 0.1 1.3 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KIR66875.1 - 0.075 12.8 0.0 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase REV PF00424.18 KIR66875.1 - 9.6 6.3 8.2 0.87 9.6 0.1 3.1 4 0 0 4 4 3 0 REV protein (anti-repression trans-activator protein) MarR_2 PF12802.7 KIR66876.1 - 1.2e-13 50.7 1.1 2.3e-13 49.8 0.6 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KIR66876.1 - 4.3e-10 39.4 0.0 9.3e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KIR66876.1 - 2.1e-05 25.0 0.1 4.2e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 KIR66876.1 - 4.3e-05 23.0 0.0 0.00023 20.6 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KIR66876.1 - 6.7e-05 22.8 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 KIR66876.1 - 0.0002 21.1 0.4 0.00065 19.5 0.1 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain GntR PF00392.21 KIR66876.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family RP-C PF03428.13 KIR66876.1 - 0.0088 15.7 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Replication protein C N-terminal domain Rrf2 PF02082.20 KIR66876.1 - 0.013 15.9 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DprA_WH PF17782.1 KIR66876.1 - 0.034 14.2 1.7 5.5 7.2 0.1 2.6 2 0 0 2 2 2 0 DprA winged helix domain HTH_34 PF13601.6 KIR66876.1 - 0.052 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_5 PF01022.20 KIR66876.1 - 0.091 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 KIR66876.1 - 0.11 12.4 0.0 0.41 10.5 0.0 2.0 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Phage_CI_repr PF07022.13 KIR66876.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain AbiEi_4 PF13338.6 KIR66876.1 - 0.16 12.1 4.1 0.46 10.7 1.2 2.7 2 1 1 3 3 3 0 Transcriptional regulator, AbiEi antitoxin PGPGW PF09656.10 KIR66877.1 - 1.8e-22 78.6 9.7 1.8e-22 78.6 9.7 2.2 2 1 0 2 2 2 1 Putative transmembrane protein (PGPGW) DUF2892 PF11127.8 KIR66877.1 - 2.4 8.3 16.0 0.53 10.4 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) MerR_1 PF13411.6 KIR66878.1 - 8e-16 57.9 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein GyrI-like PF06445.15 KIR66878.1 - 2.7e-13 50.5 0.0 8.1e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 GyrI-like small molecule binding domain MerR PF00376.23 KIR66878.1 - 3.9e-12 45.7 0.1 9.1e-12 44.6 0.1 1.7 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 KIR66878.1 - 1.2e-05 25.7 2.8 2.1e-05 24.9 2.8 1.4 1 0 0 1 1 1 1 MerR, DNA binding HTH_17 PF12728.7 KIR66878.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CBM_2 PF00553.19 KIR66879.1 - 2.8e-23 82.1 6.3 5.6e-23 81.2 6.3 1.5 1 0 0 1 1 1 1 Cellulose binding domain Peptidase_S9 PF00326.21 KIR66879.1 - 3e-05 23.6 0.0 0.003 17.1 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KIR66879.1 - 0.00011 21.7 1.5 0.00014 21.5 0.4 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KIR66879.1 - 0.00015 21.1 0.1 0.016 14.5 0.1 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KIR66879.1 - 0.00022 20.9 0.0 0.00081 19.0 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KIR66879.1 - 0.0011 17.5 0.0 0.0042 15.7 0.0 1.7 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 KIR66879.1 - 0.0034 16.1 0.0 0.095 11.4 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KIR66879.1 - 0.0051 16.7 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIR66879.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KIR66879.1 - 0.039 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 KIR66879.1 - 0.049 13.3 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KIR66879.1 - 0.053 13.2 0.1 8.7 5.9 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF1547 PF07577.11 KIR66880.1 - 0.028 14.8 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) DUF3088 PF11287.8 KIR66880.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) MMR_HSR1 PF01926.23 KIR66880.1 - 0.21 11.6 0.0 1 9.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DZR PF12773.7 KIR66880.1 - 0.24 11.5 4.6 0.63 10.1 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KIR66880.1 - 2.3 7.8 7.9 3.8 7.0 2.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-IS66 PF13005.7 KIR66880.1 - 4.3 7.8 7.4 9 6.8 0.1 3.4 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 LPMO_10 PF03067.15 KIR66881.1 - 2.3e-34 119.8 3.9 2.3e-34 119.8 3.9 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_2 PF00553.19 KIR66881.1 - 7.3e-24 84.0 13.7 7.3e-24 84.0 13.7 2.9 3 0 0 3 3 3 1 Cellulose binding domain AP3B1_C PF14796.6 KIR66882.1 - 0.049 13.9 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal ABC2_membrane PF01061.24 KIR66883.1 - 1.4e-26 93.2 8.5 2e-26 92.7 8.5 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR66883.1 - 9.2e-12 44.7 1.7 1.4e-11 44.1 1.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KIR66883.1 - 0.005 16.2 5.0 0.0061 15.9 5.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KIR66883.1 - 0.037 14.0 2.4 0.06 13.3 2.4 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SWIM PF04434.17 KIR66884.1 - 0.00037 20.1 0.2 0.00037 20.1 0.2 1.6 2 0 0 2 2 2 1 SWIM zinc finger MEDS PF14417.6 KIR66885.1 - 5.6e-36 123.8 0.8 8.1e-36 123.3 0.8 1.2 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain T2SSN PF01203.19 KIR66885.1 - 0.0056 16.9 1.1 0.011 16.0 0.3 1.8 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein N DUF397 PF04149.12 KIR66886.1 - 8.8e-21 73.7 0.1 9.7e-21 73.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF397) HTH_31 PF13560.6 KIR66887.1 - 0.082 13.3 4.3 0.11 12.9 0.5 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 KIR66887.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_26 PF13443.6 KIR66887.1 - 0.18 12.2 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.6 KIR66887.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_16 PF13191.6 KIR66888.1 - 3.3e-18 66.6 2.2 3.3e-18 66.6 2.2 2.6 3 1 1 4 4 3 1 AAA ATPase domain GerE PF00196.19 KIR66888.1 - 8.5e-13 47.6 0.0 1.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_30 PF13604.6 KIR66888.1 - 1.9e-06 27.8 1.1 0.00013 21.7 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIR66888.1 - 0.00015 22.0 0.3 0.0013 19.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain Sigma70_r4_2 PF08281.12 KIR66888.1 - 0.00022 20.8 0.1 0.00064 19.3 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 TPR_12 PF13424.6 KIR66888.1 - 0.0013 19.0 18.7 0.0066 16.7 0.8 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat HTH_40 PF14493.6 KIR66888.1 - 0.0037 17.7 0.0 0.43 11.1 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain TPR_2 PF07719.17 KIR66888.1 - 0.0052 16.8 7.3 4.6 7.6 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat HTH_23 PF13384.6 KIR66888.1 - 0.0062 16.3 0.4 0.033 14.0 0.4 2.4 1 0 0 1 1 1 1 Homeodomain-like domain cobW PF02492.19 KIR66888.1 - 0.067 12.8 0.0 0.17 11.4 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KIR66888.1 - 0.083 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KIR66888.1 - 0.091 12.7 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea HTH_24 PF13412.6 KIR66888.1 - 0.095 12.3 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran PF00005.27 KIR66888.1 - 0.19 12.3 0.0 0.53 10.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TPR_19 PF14559.6 KIR66888.1 - 0.19 12.3 15.0 6.3 7.4 0.0 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat CSD PF00313.22 KIR66889.1 - 1.5e-14 53.6 0.0 2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KIR66889.1 - 0.00067 19.3 0.5 0.0014 18.2 0.5 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain 2_5_RNA_ligase2 PF13563.6 KIR66891.1 - 4.2e-12 46.2 0.2 4.9e-12 46.0 0.2 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DNA_gyraseB PF00204.25 KIR66893.1 - 2.1e-46 157.6 0.0 3.2e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 KIR66893.1 - 1.8e-23 82.5 0.0 4.4e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 KIR66893.1 - 4.7e-16 59.3 0.1 2e-15 57.2 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIR66893.1 - 2.4e-12 46.9 0.0 6.7e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KIR66893.1 - 8.8e-05 22.3 0.1 0.00023 21.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_tran_28_C PF04101.16 KIR66894.1 - 0.0007 19.6 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 KIR66894.1 - 0.022 14.7 0.3 0.073 13.1 0.3 1.9 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 KIR66894.1 - 0.024 14.7 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain YjeF_N PF03853.15 KIR66894.1 - 0.036 13.9 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus Acetyltransf_3 PF13302.7 KIR66895.1 - 1.6e-07 32.1 0.1 2.6e-07 31.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIR66895.1 - 8e-07 28.8 0.5 1.9e-05 24.4 0.4 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIR66895.1 - 1.6e-06 28.3 0.0 2.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyl_transf_3 PF01757.22 KIR66896.1 - 7.4e-30 104.2 33.6 8.4e-30 104.0 33.6 1.0 1 0 0 1 1 1 1 Acyltransferase family RseC_MucC PF04246.12 KIR66896.1 - 5 7.1 7.7 14 5.7 1.1 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_tran PF00005.27 KIR66897.1 - 6e-16 59.2 0.1 1.4e-14 54.8 0.1 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66897.1 - 4.2e-09 36.6 1.3 1.2e-05 25.3 0.7 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR66897.1 - 5.3e-05 22.9 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR66897.1 - 7.4e-05 22.3 0.1 0.025 14.0 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIR66897.1 - 0.00056 20.3 0.0 0.0034 17.8 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIR66897.1 - 0.0035 17.9 0.2 0.0058 17.1 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIR66897.1 - 0.011 16.0 0.0 0.046 14.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIR66897.1 - 0.011 15.1 0.7 0.13 11.6 0.2 2.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 KIR66897.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KIR66897.1 - 0.018 15.5 0.1 0.029 14.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KIR66897.1 - 0.022 14.7 0.2 0.046 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIR66897.1 - 0.037 13.7 0.6 0.17 11.5 0.6 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIR66897.1 - 0.048 13.7 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 KIR66897.1 - 0.067 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 KIR66897.1 - 0.076 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KIR66897.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF1525 PF07511.11 KIR66897.1 - 0.23 11.6 0.3 0.47 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) GFO_IDH_MocA PF01408.22 KIR66898.1 - 4.7e-14 53.2 0.0 7.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PolyA_pol PF01743.20 KIR66898.1 - 0.094 13.1 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Poly A polymerase head domain NMT1_3 PF16868.5 KIR66899.1 - 6e-58 196.6 0.0 1.3e-57 195.5 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 KIR66899.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KIR66899.1 - 5.8e-11 42.8 0.0 7.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KIR66899.1 - 0.0018 17.7 0.0 0.0052 16.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2183 PF09949.9 KIR66902.1 - 1.2e-30 105.7 0.0 1.9e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Bac_transf PF02397.16 KIR66903.1 - 1.1e-53 181.6 0.0 1.2e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase Epimerase_2 PF02350.19 KIR66904.1 - 1.7e-87 293.5 0.0 2.1e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 KIR66905.1 - 2.2e-22 80.2 9.3 2.2e-22 80.2 9.3 2.8 2 1 2 4 4 4 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KIR66905.1 - 8.4e-18 64.9 2.3 8.4e-18 64.9 2.3 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIR66905.1 - 2e-16 60.7 0.5 9.3e-16 58.5 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KIR66905.1 - 3.7e-16 59.1 0.0 6.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIR66905.1 - 0.0017 18.7 0.3 0.0052 17.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIR66905.1 - 0.028 14.4 0.1 0.49 10.4 0.1 2.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like DAHP_snth_FXD PF18152.1 KIR66905.1 - 0.072 12.9 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Tex_N PF09371.10 KIR66906.1 - 4.4e-69 231.8 0.1 6.8e-69 231.2 0.1 1.3 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 KIR66906.1 - 7.7e-50 168.6 0.0 1.2e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 KIR66906.1 - 1.2e-28 99.2 0.0 2.4e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 KIR66906.1 - 8.1e-23 81.1 0.1 2.7e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 HHH domain S1 PF00575.23 KIR66906.1 - 1.3e-19 70.3 1.4 2.5e-19 69.4 1.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 KIR66906.1 - 4.7e-09 36.5 0.0 9.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 KIR66906.1 - 5.4e-05 22.7 0.1 0.0073 15.7 0.0 2.3 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K YqgF PF14639.6 KIR66906.1 - 0.0002 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 KIR66906.1 - 0.0029 17.8 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif PCB_OB PF17092.5 KIR66906.1 - 0.0048 17.6 0.2 0.014 16.1 0.1 1.8 2 0 0 2 2 1 1 Penicillin-binding protein OB-like domain HHH PF00633.23 KIR66906.1 - 0.045 13.6 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif HD PF01966.22 KIR66907.1 - 1.2e-12 48.1 0.1 3.6e-12 46.6 0.0 2.0 2 1 0 2 2 2 1 HD domain HD_assoc PF13286.6 KIR66907.1 - 6.5e-07 29.8 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Phosphohydrolase-associated domain DegT_DnrJ_EryC1 PF01041.17 KIR66908.1 - 9.4e-95 318.0 0.0 1.1e-94 317.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIR66908.1 - 1.5e-08 34.3 0.0 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIR66908.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KIR66908.1 - 0.14 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KIR66908.1 - 0.21 10.3 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta-lactamase2 PF13354.6 KIR66909.1 - 6e-35 120.7 0.0 8.6e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 KIR66909.1 - 0.012 14.9 5.6 0.019 14.3 1.7 2.4 2 1 0 2 2 2 0 Beta-lactamase LHC PF00556.20 KIR66910.1 - 0.21 11.8 0.2 0.21 11.8 0.2 3.8 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit DUF2165 PF09933.9 KIR66910.1 - 0.35 10.9 7.9 0.46 10.5 2.2 2.2 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF4381 PF14316.6 KIR66910.1 - 0.84 9.9 6.2 0.41 10.9 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FxsA PF04186.13 KIR66910.1 - 1.5 9.0 8.8 0.14 12.3 0.5 2.6 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein Ferric_reduct PF01794.19 KIR66910.1 - 2.3 8.3 10.4 3.2 7.9 1.0 2.7 1 1 2 3 3 3 0 Ferric reductase like transmembrane component FecCD PF01032.18 KIR66911.1 - 9.7e-75 251.4 33.3 1.2e-74 251.1 33.3 1.1 1 0 0 1 1 1 1 FecCD transport family Glyoxalase_4 PF13669.6 KIR66912.1 - 7.2e-15 55.2 0.1 8.9e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KIR66912.1 - 2e-11 44.1 0.0 2.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KIR66912.1 - 1e-07 32.2 1.2 3e-07 30.7 1.2 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KIR66912.1 - 0.0022 18.8 1.2 0.02 15.6 1.2 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain PHP_C PF13263.6 KIR66913.1 - 0.00018 21.2 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 PHP-associated PHP PF02811.19 KIR66913.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 PHP domain Sortase PF04203.13 KIR66914.1 - 4.7e-17 62.0 0.0 5.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Sortase domain DUF4386 PF14329.6 KIR66915.1 - 7.5e-46 156.6 26.1 8.6e-46 156.5 26.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) Urease_gamma PF00547.18 KIR66915.1 - 0.15 12.4 0.3 0.25 11.7 0.3 1.4 1 0 0 1 1 1 0 Urease, gamma subunit 7TMR-DISM_7TM PF07695.11 KIR66915.1 - 1.4 8.8 10.2 1 9.2 1.4 2.5 1 1 0 2 2 2 0 7TM diverse intracellular signalling MFS_1 PF07690.16 KIR66917.1 - 2.3e-27 95.9 82.3 1.5e-22 80.0 53.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIR66917.1 - 0.00057 19.3 47.4 0.006 15.9 47.4 2.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Phage_holin_3_2 PF04550.12 KIR66917.1 - 0.022 15.3 4.5 0.022 15.3 4.5 3.4 2 1 1 3 3 3 0 Phage holin family 2 Virul_fac_BrkB PF03631.15 KIR66918.1 - 1.8e-59 201.4 20.8 2.1e-59 201.3 20.8 1.0 1 0 0 1 1 1 1 Virulence factor BrkB Amino_oxidase PF01593.24 KIR66919.1 - 4.3e-11 42.8 4.3 5.8e-06 25.8 0.1 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIR66919.1 - 7e-09 35.8 0.3 7e-09 35.8 0.3 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIR66919.1 - 1.2e-05 24.2 0.2 0.022 13.5 1.2 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KIR66919.1 - 7.6e-05 22.5 10.0 0.00077 19.1 0.9 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KIR66919.1 - 0.00011 21.5 0.6 0.0002 20.7 0.6 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KIR66919.1 - 0.00027 20.3 0.8 0.00048 19.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 KIR66919.1 - 0.00033 20.1 0.5 0.059 12.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 KIR66919.1 - 0.0015 17.7 9.7 0.014 14.5 9.7 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIR66919.1 - 0.043 13.1 0.7 0.099 11.8 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIR66919.1 - 0.048 12.7 2.0 0.24 10.5 2.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIR66919.1 - 0.12 11.7 5.8 0.1 11.9 4.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIR66919.1 - 0.22 12.1 0.8 1.9 9.1 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIR66919.1 - 0.33 9.9 2.3 18 4.3 1.5 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Glyco_transf_4 PF13439.6 KIR66920.1 - 6e-36 124.0 3.5 6e-36 124.0 3.5 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIR66920.1 - 6.6e-36 123.4 0.0 1.4e-35 122.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIR66920.1 - 1.6e-31 109.9 15.2 1.6e-31 109.9 15.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KIR66920.1 - 1.2e-30 106.7 0.1 2.9e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIR66920.1 - 8.7e-09 35.7 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIR66920.1 - 2e-07 31.0 0.1 0.0038 17.0 0.0 2.3 2 0 0 2 2 2 2 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 KIR66920.1 - 7.4e-06 26.0 0.0 2.6e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glycogen_syn PF05693.13 KIR66920.1 - 0.003 16.2 0.1 0.02 13.4 0.1 1.9 2 0 0 2 2 2 1 Glycogen synthase pPIWI_RE_REase PF18154.1 KIR66920.1 - 0.073 13.0 0.2 0.3 11.1 0.0 2.1 3 0 0 3 3 3 0 REase associating with pPIWI_RE HAMP PF00672.25 KIR66921.1 - 1.4e-09 38.2 0.5 1.4e-09 38.2 0.5 2.8 3 0 0 3 3 3 1 HAMP domain HATPase_c PF02518.26 KIR66921.1 - 6.8e-08 33.0 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIR66921.1 - 4.5e-06 26.6 0.3 8.2e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KIR66921.1 - 0.018 15.0 0.1 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain CrgA PF06781.12 KIR66921.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein CrgA Peptidase_M15_3 PF08291.11 KIR66922.1 - 9.4e-29 99.7 0.0 1.2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase M15 PG_binding_1 PF01471.18 KIR66922.1 - 5.6e-17 61.7 0.1 9.1e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 KIR66922.1 - 0.0012 19.0 0.1 1.5 9.2 0.0 2.6 1 1 1 2 2 2 2 Predicted Peptidoglycan domain Extensin-like_C PF06904.12 KIR66922.1 - 0.0025 17.9 1.2 0.7 9.9 0.2 2.2 1 1 1 2 2 2 2 Extensin-like protein C-terminus Peptidase_M15_2 PF05951.13 KIR66922.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF402 PF04167.13 KIR66923.1 - 5.9e-11 42.4 0.4 1e-10 41.7 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF402) p450 PF00067.22 KIR66924.1 - 5.6e-30 104.5 0.0 7.3e-23 81.0 0.1 3.1 1 1 1 2 2 2 2 Cytochrome P450 Fer4_15 PF13459.6 KIR66925.1 - 7.4e-11 42.6 0.6 9.6e-11 42.3 0.6 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 KIR66925.1 - 3e-10 40.0 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_13 PF13370.6 KIR66925.1 - 3.2e-10 40.4 0.1 3.5e-10 40.3 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_6 PF12837.7 KIR66925.1 - 0.038 14.1 0.6 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KIR66925.1 - 0.11 12.6 1.1 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain OAM_dimer PF16554.5 KIR66925.1 - 0.16 12.4 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase p450 PF00067.22 KIR66926.1 - 1.9e-26 92.8 0.0 1.7e-23 83.1 0.2 3.0 2 1 0 2 2 2 1 Cytochrome P450 IspD PF01128.19 KIR66926.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DHDPS PF00701.22 KIR66927.1 - 0.00019 20.3 0.0 0.00031 19.6 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribosomal_L18p PF00861.22 KIR66927.1 - 0.033 14.5 1.4 0.069 13.5 1.4 1.5 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ring_hydroxyl_B PF00866.18 KIR66929.1 - 6.8e-29 100.8 2.5 7.8e-29 100.6 2.5 1.0 1 0 0 1 1 1 1 Ring hydroxylating beta subunit RicinB_lectin_2 PF14200.6 KIR66930.1 - 4.9e-36 123.3 16.2 4.4e-22 78.6 4.4 3.3 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIR66930.1 - 9.3e-14 51.8 3.5 2.1e-13 50.6 3.4 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Esterase PF00756.20 KIR66930.1 - 0.00096 18.9 0.5 0.0051 16.5 0.5 2.2 1 1 0 1 1 1 1 Putative esterase PAS_7 PF12860.7 KIR66930.1 - 0.0051 17.0 0.0 0.27 11.4 0.0 2.4 1 1 1 2 2 2 1 PAS fold Peptidase_S9 PF00326.21 KIR66930.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIR66930.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rhomboid_SP PF12595.8 KIR66930.1 - 0.22 10.8 0.1 0.41 10.0 0.1 1.4 1 0 0 1 1 1 0 Rhomboid serine protease Amidohydro_2 PF04909.14 KIR66931.1 - 7.6e-45 153.9 7.9 8.9e-45 153.7 7.9 1.0 1 0 0 1 1 1 1 Amidohydrolase TetR_C_11 PF16859.5 KIR66932.1 - 1.2e-23 83.6 7.8 1.2e-23 83.6 7.8 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 KIR66932.1 - 6.2e-11 41.9 0.0 1.7e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 KIR66932.1 - 0.01 15.6 0.3 0.04 13.7 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 KIR66932.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LacI PF00356.21 KIR66932.1 - 0.019 14.8 0.2 0.067 13.0 0.2 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 KIR66932.1 - 6.5 6.7 7.7 1.6 8.6 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain AAA PF00004.29 KIR66933.1 - 7.5e-38 129.9 0.0 6.2e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KIR66933.1 - 2.1e-24 85.5 4.5 6.6e-13 48.6 0.2 3.2 4 0 0 4 4 2 2 AAA lid domain Beta_helix PF13229.6 KIR66933.1 - 5.3e-18 65.4 0.0 5.1e-07 29.7 0.0 3.2 1 1 2 3 3 3 3 Right handed beta helix region AAA_22 PF13401.6 KIR66933.1 - 4.9e-11 43.1 0.5 0.0043 17.3 0.1 4.5 2 2 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KIR66933.1 - 2.4e-10 40.5 0.9 0.00061 19.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIR66933.1 - 3.6e-08 33.0 2.7 0.038 13.4 0.1 4.2 2 2 2 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KIR66933.1 - 1.3e-07 32.2 3.4 0.0013 19.1 0.3 3.1 2 1 1 3 3 2 2 AAA ATPase domain DUF815 PF05673.13 KIR66933.1 - 1e-06 28.1 0.9 0.89 8.7 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIR66933.1 - 1.4e-06 28.1 0.9 0.025 14.4 0.1 3.2 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIR66933.1 - 5.7e-06 26.4 0.1 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIR66933.1 - 6.2e-06 26.8 0.1 0.14 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KIR66933.1 - 9.2e-06 25.9 0.1 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIR66933.1 - 2.4e-05 24.7 0.2 0.29 11.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KIR66933.1 - 5.5e-05 22.9 0.4 0.28 10.9 0.0 4.0 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 KIR66933.1 - 0.00022 21.5 0.3 0.8 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 KIR66933.1 - 0.0016 18.3 0.8 0.68 9.8 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.6 KIR66933.1 - 0.002 17.9 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIR66933.1 - 0.0029 17.2 5.2 0.92 9.0 0.4 2.9 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KIR66933.1 - 0.0046 17.1 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF853 PF05872.12 KIR66933.1 - 0.0071 15.0 1.6 0.74 8.3 0.1 3.1 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) Viral_helicase1 PF01443.18 KIR66933.1 - 0.0071 16.1 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KIR66933.1 - 0.01 15.7 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIR66933.1 - 0.016 14.7 0.1 5 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 KIR66933.1 - 0.019 14.8 0.0 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KIR66933.1 - 0.02 13.8 0.1 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KIR66933.1 - 0.049 14.0 0.1 6.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NosD PF05048.13 KIR66933.1 - 0.057 12.7 0.0 3.8 6.7 0.0 2.4 1 1 2 3 3 3 0 Periplasmic copper-binding protein (NosD) T2SSE PF00437.20 KIR66933.1 - 0.079 12.0 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIR66933.1 - 0.099 11.9 0.4 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 KIR66933.1 - 0.1 11.9 0.0 14 4.9 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.6 KIR66933.1 - 0.1 13.0 0.6 15 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain DinB_2 PF12867.7 KIR66933.1 - 0.14 12.7 5.2 0.98 9.9 0.0 3.3 3 1 0 3 3 3 0 DinB superfamily DUF1565 PF07602.11 KIR66933.1 - 0.15 11.4 0.5 7.2 5.9 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1565) TIP49 PF06068.13 KIR66933.1 - 0.17 11.1 0.5 1.1e+02 1.8 0.0 3.9 3 1 2 5 5 5 0 TIP49 P-loop domain TsaE PF02367.17 KIR66933.1 - 0.17 11.9 0.1 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KTI12 PF08433.10 KIR66933.1 - 0.18 11.3 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 KIR66933.1 - 0.43 9.8 2.2 6.1 6.0 0.1 2.5 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ricin_B_lectin PF00652.22 KIR66934.1 - 4.2e-22 78.7 3.2 4.6e-22 78.6 3.2 1.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66934.1 - 9e-13 48.8 9.5 5.4e-06 27.0 1.5 3.0 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like SH3_4 PF06347.13 KIR66934.1 - 0.031 14.1 0.3 1.9 8.4 0.0 2.5 2 1 0 2 2 2 0 Bacterial SH3 domain OmdA PF13376.6 KIR66935.1 - 2.6e-20 72.2 2.7 2.6e-20 72.2 2.7 1.8 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated PG_binding_1 PF01471.18 KIR66936.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 1 0 1 1 1 1 Putative peptidoglycan binding domain FliMN_C PF01052.20 KIR66936.1 - 0.089 12.8 0.9 0.48 10.5 0.3 2.6 3 0 0 3 3 3 0 Type III flagellar switch regulator (C-ring) FliN C-term DUF1905 PF08922.11 KIR66936.1 - 0.21 11.7 2.4 0.53 10.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) Allantoicase PF03561.15 KIR66937.1 - 1.5e-86 287.6 0.0 3.6e-42 143.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Amidohydro_1 PF01979.20 KIR66938.1 - 8.7e-55 186.4 0.0 1.1e-54 186.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIR66938.1 - 5.7e-12 45.9 4.8 1.1e-09 38.3 3.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family PucR PF07905.11 KIR66939.1 - 1.7e-26 92.8 0.0 3.7e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 KIR66939.1 - 8.5e-22 76.7 2.2 2.1e-21 75.5 2.2 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 KIR66939.1 - 4.9e-07 30.0 4.6 4.9e-07 30.0 4.6 3.4 2 1 1 3 3 3 1 GGDEF-like domain IclR PF01614.18 KIR66940.1 - 1.6e-26 92.6 0.0 3.3e-26 91.6 0.0 1.4 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 KIR66940.1 - 9.2e-18 63.8 4.0 1.8e-17 62.9 4.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 KIR66940.1 - 3.2e-07 30.1 1.8 1e-06 28.5 1.8 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KIR66940.1 - 0.0037 16.8 0.1 0.0071 15.9 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KIR66940.1 - 0.0045 17.0 1.7 0.013 15.6 1.7 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain RP-C PF03428.13 KIR66940.1 - 0.014 15.0 0.2 0.027 14.1 0.2 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain MarR PF01047.22 KIR66940.1 - 0.019 14.9 0.4 0.038 13.9 0.1 1.6 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 KIR66940.1 - 0.034 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_26 PF13443.6 KIR66940.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PIG-L PF02585.17 KIR66941.1 - 1.3e-28 100.3 0.3 3.4e-28 98.9 0.3 1.7 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Peripla_BP_3 PF13377.6 KIR66942.1 - 1.1e-40 139.7 3.1 2.4e-40 138.6 1.6 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 KIR66942.1 - 5.6e-27 94.9 0.0 7.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 KIR66942.1 - 1e-16 61.3 0.0 1.4e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 KIR66942.1 - 1.4e-13 50.4 1.1 2.8e-13 49.4 1.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 KIR66942.1 - 0.013 15.9 0.2 0.05 14.0 0.2 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 KIR66942.1 - 0.069 13.0 0.4 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KIR66942.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Peripla_BP_2 PF01497.18 KIR66942.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein AAA_33 PF13671.6 KIR66943.1 - 0.0056 16.9 0.3 0.0069 16.6 0.3 1.1 1 0 0 1 1 1 1 AAA domain DUF2267 PF10025.9 KIR66944.1 - 0.095 13.0 2.1 0.24 11.7 2.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) FCD PF07729.12 KIR66945.1 - 2.2e-24 86.2 10.6 3.4e-24 85.6 10.6 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 KIR66945.1 - 3.8e-17 61.7 0.1 1.3e-16 60.0 0.1 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FadR_C PF07840.12 KIR66945.1 - 0.0029 17.5 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 FadR C-terminal domain HTH_11 PF08279.12 KIR66945.1 - 0.0082 16.1 0.2 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 KIR66945.1 - 0.049 13.5 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TetR_C_15 PF17918.1 KIR66945.1 - 0.05 14.4 0.5 0.05 14.4 0.5 2.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rrf2 PF02082.20 KIR66945.1 - 0.072 13.5 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Ribosomal_S19e PF01090.19 KIR66945.1 - 0.075 12.7 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S19e HicA_toxin PF07927.12 KIR66945.1 - 0.11 12.6 0.0 0.95 9.5 0.0 2.4 3 0 0 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, DELLA PF12041.8 KIR66945.1 - 0.13 12.2 0.5 0.42 10.5 0.5 1.9 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal BPD_transp_1 PF00528.22 KIR66946.1 - 5e-10 39.4 19.9 5e-10 39.4 19.9 1.7 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ArabFuran-catal PF09206.11 KIR66947.1 - 1.4e-132 441.8 11.3 1.4e-132 441.8 11.3 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic Ricin_B_lectin PF00652.22 KIR66947.1 - 3.3e-28 98.5 12.7 8.3e-28 97.2 12.7 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIR66947.1 - 6.9e-21 74.8 31.5 8.3e-08 32.9 1.4 4.6 4 1 2 6 6 6 3 Ricin-type beta-trefoil lectin domain-like CHASE3 PF05227.13 KIR66948.1 - 0.041 13.8 0.7 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 CHASE3 domain AAA_5 PF07728.14 KIR66949.1 - 1.7e-35 122.0 0.0 2.9e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIR66949.1 - 0.00093 19.6 0.1 0.0019 18.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KIR66949.1 - 0.003 17.0 0.2 0.0053 16.2 0.2 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIR66949.1 - 0.0063 16.4 0.0 0.13 12.2 0.0 2.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIR66949.1 - 0.0085 15.8 0.1 0.52 10.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KIR66949.1 - 0.023 15.1 0.2 0.23 11.9 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VWA_CoxE PF05762.14 KIR66950.1 - 7.6e-58 195.5 2.4 1.8e-57 194.3 2.4 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 KIR66950.1 - 0.00037 21.1 0.2 0.002 18.7 0.2 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain ABC_tran PF00005.27 KIR66951.1 - 9e-28 97.5 0.0 1.2e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR66951.1 - 2.6e-06 27.5 0.0 0.0046 16.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KIR66951.1 - 0.00017 21.2 0.4 0.044 13.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIR66951.1 - 0.00027 21.3 1.0 0.00038 20.9 1.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIR66951.1 - 0.0009 19.5 0.7 0.0077 16.5 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR66951.1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR66951.1 - 0.0089 15.5 0.0 0.037 13.5 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain oligo_HPY PF08352.12 KIR66951.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region IstB_IS21 PF01695.17 KIR66951.1 - 0.017 14.8 0.2 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 KIR66951.1 - 0.057 12.9 0.3 0.21 11.0 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 KIR66951.1 - 0.058 13.3 0.2 0.13 12.2 0.2 1.5 1 1 0 1 1 1 0 NACHT domain DEAD PF00270.29 KIR66951.1 - 0.07 12.9 0.1 0.91 9.3 0.1 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KIR66951.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIR66951.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 KIR66951.1 - 0.2 10.8 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 KIR66951.1 - 0.2 10.8 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 KIR66951.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain BPD_transp_1 PF00528.22 KIR66952.1 - 4e-28 98.4 11.3 5.6e-28 97.9 11.3 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component AMP-binding PF00501.28 KIR66953.1 - 3e-87 293.0 0.0 3.5e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR66953.1 - 6.1e-25 88.0 1.1 1.8e-24 86.5 1.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KIR66954.1 - 1.7e-96 323.5 0.0 2e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIR66954.1 - 1.6e-20 73.9 1.9 1.9e-20 73.6 0.4 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glycos_transf_2 PF00535.26 KIR66955.1 - 3.5e-31 108.3 0.0 5.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66955.1 - 6.1e-25 88.4 7.8 7.8e-24 84.8 7.8 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 KIR66955.1 - 9.6e-14 50.9 0.0 1.3e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIR66955.1 - 2.8e-09 37.2 11.5 2.8e-09 37.2 11.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KIR66955.1 - 3.8e-08 33.0 2.8 6.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KIR66955.1 - 5.3e-08 32.7 0.0 7.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KIR66955.1 - 0.00024 21.6 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 UDPG_MGDP_dh_N PF03721.14 KIR66956.1 - 3.5e-36 124.5 0.0 7.1e-36 123.5 0.0 1.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KIR66956.1 - 5.9e-28 96.9 0.0 1.1e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KIR66956.1 - 5.6e-11 42.8 0.0 2.8e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 KIR66956.1 - 8.9e-06 26.0 0.0 2.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KIR66956.1 - 0.0004 20.3 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KIR66956.1 - 0.0023 17.6 0.0 0.0087 15.7 0.0 2.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KIR66956.1 - 0.012 14.9 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KIR66956.1 - 0.08 13.2 0.6 0.52 10.6 0.3 2.4 2 1 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.21 KIR66956.1 - 0.091 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 KIR66956.1 - 0.18 11.8 0.5 2.4 8.2 0.1 2.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIR66957.1 - 3.2e-19 70.3 0.1 6.3e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIR66957.1 - 7.7e-10 38.9 0.0 1.8e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIR66957.1 - 8.7e-08 32.0 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 KIR66957.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KIR66957.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_43 PF04616.14 KIR66958.1 - 6e-52 176.7 3.5 7.6e-52 176.4 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KIR66958.1 - 2.2e-39 134.6 1.6 2.2e-39 134.6 1.6 2.6 2 1 1 3 3 3 1 Carbohydrate binding module (family 6) CBM_2 PF00553.19 KIR66958.1 - 4.9e-25 87.8 10.6 4.9e-25 87.8 10.6 2.7 4 0 0 4 4 4 1 Cellulose binding domain DUF5010_C PF18099.1 KIR66958.1 - 4.6e-10 39.6 0.4 4.6e-10 39.6 0.4 2.1 2 0 0 2 2 2 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KIR66958.1 - 0.014 15.0 3.4 0.02 14.5 2.9 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DUF11 PF01345.18 KIR66958.1 - 0.015 15.6 1.8 0.05 13.9 1.8 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 Peptidase_M23 PF01551.22 KIR66959.1 - 2.1e-20 72.7 0.2 4.2e-20 71.8 0.2 1.4 1 1 0 1 1 1 1 Peptidase family M23 Trans_reg_C PF00486.28 KIR66960.1 - 3.4e-13 49.5 0.5 5.1e-13 48.9 0.5 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF3558 PF12079.8 KIR66961.1 - 2.8e-05 24.2 1.4 3.3e-05 24.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) MDMPI_N PF11716.8 KIR66962.1 - 2.3e-09 38.1 13.3 1.3e-08 35.7 7.5 2.8 2 1 1 3 3 3 2 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 KIR66962.1 - 0.0011 19.5 0.4 0.0033 17.9 0.4 1.9 1 1 0 1 1 1 1 DinB superfamily MDMPI_C PF07398.11 KIR66962.1 - 0.0081 17.0 8.5 0.0081 17.0 8.5 2.6 2 1 0 2 2 2 1 MDMPI C-terminal domain SBF_like PF13593.6 KIR66964.1 - 6.7e-86 288.4 19.3 7.5e-86 288.3 19.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 KIR66964.1 - 1.5e-11 44.3 8.7 1.5e-11 44.3 8.7 1.9 1 1 1 2 2 2 1 Sodium Bile acid symporter family Response_reg PF00072.24 KIR66965.1 - 1.4e-22 80.0 0.0 1.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 KIR66965.1 - 4.4e-15 55.5 0.1 1.2e-14 54.1 0.2 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Spo0M PF07070.11 KIR66966.1 - 1.7e-77 259.7 0.0 2.1e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 SpoOM protein DUF2076 PF09849.9 KIR66966.1 - 0.15 12.1 8.9 0.25 11.4 8.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_hydro_42 PF02449.15 KIR66967.1 - 1.2e-132 442.8 0.0 1.5e-132 442.4 0.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 KIR66967.1 - 3.7e-48 163.8 0.0 6e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.10 KIR66967.1 - 2.2e-09 36.9 0.2 7e-09 35.3 0.2 1.9 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Glyco_hydro_14 PF01373.17 KIR66967.1 - 1.9e-05 23.8 0.2 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 Cellulase PF00150.18 KIR66967.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) SnoaL_2 PF12680.7 KIR66968.1 - 9.6e-20 71.1 3.1 1.1e-19 70.9 3.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KIR66968.1 - 1e-11 44.7 0.1 1.9e-11 43.9 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 KIR66968.1 - 1.2e-07 32.0 0.3 1.7e-07 31.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) PfkB PF00294.24 KIR66969.1 - 1.7e-56 191.8 4.1 1.9e-56 191.6 4.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIR66969.1 - 2.5e-07 30.3 0.3 5.2e-07 29.3 0.3 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase GerE PF00196.19 KIR66970.1 - 1.1e-07 31.3 0.0 3.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 KIR66970.1 - 8.3e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66970.1 - 8.5e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Response_reg PF00072.24 KIR66970.1 - 0.00064 19.9 0.0 0.00085 19.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_38 PF13936.6 KIR66970.1 - 0.068 12.9 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Crp PF00325.20 KIR66970.1 - 0.098 12.3 0.6 0.37 10.5 0.3 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_29 PF13551.6 KIR66970.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Pectinesterase PF01095.19 KIR66971.1 - 1.6e-51 174.8 1.4 1.6e-51 174.8 1.4 1.4 2 0 0 2 2 2 1 Pectinesterase CBM_2 PF00553.19 KIR66971.1 - 4.9e-25 87.8 11.5 1.6e-24 86.1 11.5 2.0 1 0 0 1 1 1 1 Cellulose binding domain Clr2 PF10383.9 KIR66971.1 - 0.13 13.0 0.1 0.28 12.0 0.1 1.5 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DUF5092 PF17010.5 KIR66971.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5092) p450 PF00067.22 KIR66972.1 - 2.2e-71 241.0 0.0 2.6e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_r2 PF04542.14 KIR66973.1 - 2.7e-15 55.9 2.4 4.3e-15 55.2 0.4 2.2 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 KIR66973.1 - 2.1e-12 46.5 0.3 3.8e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR66973.1 - 1.2e-06 27.9 0.4 2.2e-06 27.1 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 DUF4440 PF14534.6 KIR66973.1 - 0.00058 20.2 0.1 0.0014 19.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KIR66973.1 - 0.00065 20.3 0.4 0.00065 20.3 0.4 1.8 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.6 KIR66973.1 - 0.095 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Peripla_BP_3 PF13377.6 KIR66974.1 - 5.4e-40 137.4 1.0 5.4e-40 137.4 1.0 2.2 3 0 0 3 3 3 1 Periplasmic binding protein-like domain LacI PF00356.21 KIR66974.1 - 8.8e-17 60.6 0.1 1.9e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 KIR66974.1 - 1e-15 58.0 0.0 1.8e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 KIR66974.1 - 3.4e-15 56.2 0.0 4.5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_31 PF13560.6 KIR66974.1 - 0.0013 19.1 0.6 0.0038 17.5 0.6 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Acetyltransf_5 PF13444.6 KIR66974.1 - 0.0077 16.9 1.0 0.06 14.1 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain HTH_Tnp_ISL3 PF13542.6 KIR66974.1 - 0.15 11.5 1.4 0.35 10.3 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Diphthamide_syn PF01866.17 KIR66974.1 - 0.22 10.9 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Peripla_BP_5 PF13433.6 KIR66975.1 - 1.2e-148 494.9 1.1 1.5e-148 494.6 1.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 KIR66975.1 - 1e-81 275.3 11.7 1.3e-81 275.0 11.7 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 KIR66975.1 - 3.5e-07 29.7 0.0 4.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region ABC_tran PF00005.27 KIR66976.1 - 1.6e-23 83.8 0.0 2.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 KIR66976.1 - 2.3e-09 36.9 0.7 6.1e-09 35.6 0.1 2.0 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 KIR66976.1 - 1.1e-07 32.0 0.0 5.2e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIR66976.1 - 1.2e-06 28.1 0.1 2.3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIR66976.1 - 0.00011 21.7 0.0 0.0072 15.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR66976.1 - 0.00024 21.6 0.0 0.00032 21.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 KIR66976.1 - 0.0019 17.8 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIR66976.1 - 0.004 16.9 2.5 0.012 15.4 2.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIR66976.1 - 0.0072 16.7 1.1 0.015 15.6 1.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIR66976.1 - 0.013 15.9 0.2 0.11 12.9 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIR66976.1 - 0.025 14.9 0.2 1.6 9.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIR66976.1 - 0.028 14.6 0.3 0.062 13.5 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIR66976.1 - 0.077 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIR66976.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KIR66976.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 KIR66976.1 - 0.16 11.9 0.3 1.2 9.1 0.1 2.3 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CBM_2 PF00553.19 KIR66977.1 - 5.3e-19 68.4 11.9 1.8e-18 66.7 11.9 2.0 1 0 0 1 1 1 1 Cellulose binding domain fn3 PF00041.21 KIR66977.1 - 2.5e-09 37.3 4.6 4.9e-09 36.4 0.1 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Glyco_hydro_30C PF17189.4 KIR66977.1 - 7e-05 23.0 0.1 0.00024 21.2 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Sensor PF13796.6 KIR66978.1 - 3.6e-18 66.1 23.9 3.6e-18 66.1 23.9 2.1 2 0 0 2 2 2 1 Putative sensor HisKA_3 PF07730.13 KIR66978.1 - 9.5e-12 45.3 4.2 9.5e-12 45.3 4.2 2.7 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 KIR66978.1 - 0.00011 22.7 0.0 0.0053 17.3 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KIR66978.1 - 0.00078 19.4 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DHQS PF01959.16 KIR66979.1 - 1.5e-90 303.6 0.1 1.8e-90 303.4 0.1 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II Ketoacyl-synt_C PF02801.22 KIR66980.1 - 8.7e-28 96.7 1.6 1.1e-27 96.3 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KIR66980.1 - 2.4e-12 47.0 10.8 1.7e-10 40.9 10.8 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIR66980.1 - 0.0002 21.2 0.5 0.0014 18.4 0.5 2.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KIR66980.1 - 0.014 14.7 0.2 0.021 14.2 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain GFO_IDH_MocA PF01408.22 KIR66981.1 - 1.5e-15 58.1 0.0 2.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIR66981.1 - 1.4e-08 34.7 0.0 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KIR66981.1 - 0.00052 20.5 0.1 0.00091 19.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KIR66981.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KIR66981.1 - 0.0011 19.2 0.2 0.0022 18.2 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KIR66981.1 - 0.0021 17.5 0.1 0.0033 16.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIR66981.1 - 0.0066 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 KIR66981.1 - 0.0098 16.0 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 KIR66981.1 - 0.014 15.3 0.5 0.014 15.3 0.5 1.8 2 0 0 2 2 2 0 NAD(P)H-binding Gp_dh_N PF00044.24 KIR66981.1 - 0.16 12.3 0.0 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PDH PF02153.17 KIR66981.1 - 0.18 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase ThiF PF00899.21 KIR66981.1 - 0.22 10.8 0.3 0.47 9.8 0.3 1.5 1 0 0 1 1 1 0 ThiF family Methyltransf_21 PF05050.12 KIR66982.1 - 1.1e-14 54.8 0.0 1.5e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain PCMT PF01135.19 KIR66982.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) V_cholerae_RfbT PF05575.11 KIR66982.1 - 0.0018 17.6 0.0 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Vibrio cholerae RfbT protein Met_10 PF02475.16 KIR66982.1 - 0.0056 16.5 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_24 PF13578.6 KIR66982.1 - 0.016 16.3 0.0 0.033 15.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Phage_min_cap2 PF06152.11 KIR66982.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 FtsJ PF01728.19 KIR66982.1 - 0.2 11.7 0.0 0.37 10.9 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase NTP_transf_2 PF01909.23 KIR66983.1 - 4.9e-08 33.1 0.0 6.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIR66983.1 - 1.6e-06 28.1 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF4037 PF13228.6 KIR66983.1 - 0.0058 17.4 0.0 0.01 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) ACP_syn_III PF08545.10 KIR66984.1 - 1.1e-14 54.0 0.2 2.4e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KIR66984.1 - 1.6e-14 53.8 0.0 2.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 KIR66984.1 - 1.4e-06 27.9 0.1 2.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KIR66984.1 - 0.00084 19.0 6.8 0.034 13.7 2.4 2.9 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.12 KIR66984.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Glycos_transf_2 PF00535.26 KIR66985.1 - 2.1e-24 86.3 0.0 3.2e-24 85.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIR66985.1 - 4.1e-11 43.2 0.9 5.1e-11 42.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIR66985.1 - 0.00029 20.4 0.0 0.00074 19.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KIR66985.1 - 0.012 16.2 0.0 0.029 14.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 Rhamno_transf PF11316.8 KIR66985.1 - 0.03 13.7 0.1 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative rhamnosyl transferase NTP_transf_3 PF12804.7 KIR66985.1 - 0.29 11.5 5.8 0.29 11.5 3.9 1.9 1 1 1 2 2 2 0 MobA-like NTP transferase domain p450 PF00067.22 KIR66986.1 - 9.3e-06 24.6 0.0 0.0072 15.1 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 Epimerase PF01370.21 KIR66987.1 - 9.5e-19 67.8 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIR66987.1 - 7.6e-13 48.1 0.0 3.8e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIR66987.1 - 3.3e-12 46.1 0.0 4.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIR66987.1 - 2.4e-07 30.2 0.0 8.5e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIR66987.1 - 2.8e-05 23.7 0.0 0.0075 15.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KIR66987.1 - 0.00055 19.9 3.6 0.006 16.5 2.9 2.7 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIR66987.1 - 0.011 15.3 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family SDH_sah PF01972.16 KIR66987.1 - 0.11 11.5 0.3 0.45 9.5 0.0 1.9 2 0 0 2 2 2 0 Serine dehydrogenase proteinase SLATT_1 PF18181.1 KIR66987.1 - 0.14 12.0 0.3 0.33 10.9 0.3 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 NYN PF01936.18 KIR66988.1 - 1.2e-33 116.7 0.0 1.9e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KIR66988.1 - 7.2e-13 48.2 0.0 3.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 OST-HTH/LOTUS domain PIN7 PF18475.1 KIR66988.1 - 0.035 14.7 0.0 0.074 13.7 0.0 1.5 1 0 0 1 1 1 0 PIN domain DUF1398 PF07166.11 KIR66988.1 - 0.26 11.4 0.0 0.56 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) GTP_EFTU PF00009.27 KIR66989.1 - 1.4e-40 138.9 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIR66989.1 - 1.7e-06 28.1 0.0 1.3e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIR66989.1 - 7.3e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ABC2_membrane PF01061.24 KIR66990.1 - 5e-16 58.8 14.5 6.5e-16 58.4 14.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KIR66990.1 - 0.00015 21.0 11.0 0.00019 20.7 11.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF997 PF06196.12 KIR66990.1 - 4 7.5 15.4 0.16 12.0 0.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF997) Cellulase PF00150.18 KIR66991.1 - 3e-46 158.1 0.9 4.2e-46 157.6 0.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_2 PF00553.19 KIR66991.1 - 3.5e-29 101.1 8.9 9.4e-29 99.7 8.9 1.8 1 0 0 1 1 1 1 Cellulose binding domain Aldolase_II PF00596.21 KIR66992.1 - 1.5e-47 162.0 0.3 1.7e-47 161.7 0.3 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Glyco_hydro_43 PF04616.14 KIR66993.1 - 2.1e-79 266.9 7.2 8.1e-69 232.1 2.5 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Laminin_G_3 PF13385.6 KIR66993.1 - 4.4e-21 75.6 4.7 1.1e-20 74.3 3.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_32N PF00251.20 KIR66993.1 - 7.4e-07 29.0 0.5 0.00062 19.4 0.6 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain DUF5018 PF16410.5 KIR66993.1 - 3.9e-05 22.5 0.0 7.9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5018) Sialidase PF02973.16 KIR66993.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Sialidase, N-terminal domain Ion_trans PF00520.31 KIR66994.1 - 3.5e-36 124.7 1.3 4e-36 124.5 1.3 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KIR66994.1 - 4.3e-12 45.5 1.5 7.7e-12 44.6 1.4 1.4 1 1 1 2 2 2 1 Polycystin cation channel DUF2157 PF09925.9 KIR66994.1 - 0.0038 17.0 3.7 0.0038 17.0 3.7 2.0 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) DUF1996 PF09362.10 KIR66995.1 - 5.5e-51 173.8 0.0 6.9e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SBP_bac_8 PF13416.6 KIR66996.1 - 3.2e-26 92.8 5.4 4.5e-26 92.3 5.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 KIR66996.1 - 1.5e-22 81.0 10.7 2.3e-22 80.4 10.7 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Glycos_transf_1 PF00534.20 KIR66997.1 - 2.7e-28 98.7 0.0 4.5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIR66997.1 - 9.6e-26 90.8 0.4 8.9e-25 87.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIR66997.1 - 2.2e-08 34.3 7.0 4.5e-08 33.3 0.2 3.6 2 2 1 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIR66997.1 - 1.8e-05 25.1 0.0 9.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Methyltransf_25 PF13649.6 KIR66998.1 - 8.8e-08 32.8 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIR66998.1 - 0.00014 21.7 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIR66998.1 - 0.00026 21.6 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIR66998.1 - 0.0091 16.7 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RibD_C PF01872.17 KIR66999.1 - 5.7e-40 137.3 0.0 6.3e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain IucA_IucC PF04183.12 KIR67000.1 - 1.2e-77 260.7 0.1 1.9e-77 260.1 0.1 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 KIR67000.1 - 2.7e-39 135.2 1.3 5.5e-39 134.2 1.3 1.6 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter SHOCT PF09851.9 KIR67000.1 - 0.024 14.4 0.0 0.069 12.9 0.0 1.9 1 0 0 1 1 1 0 Short C-terminal domain Asp_Glu_race PF01177.22 KIR67001.1 - 0.0074 16.1 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase DAO PF01266.24 KIR67002.1 - 3.9e-59 201.0 7.9 4.6e-59 200.8 7.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIR67002.1 - 6.1e-09 35.5 0.5 0.00039 19.7 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIR67002.1 - 2.8e-08 34.2 0.2 0.00019 21.9 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIR67002.1 - 5.5e-08 31.9 0.2 0.0032 16.2 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KIR67002.1 - 6.9e-08 32.0 5.3 2.9e-05 23.3 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIR67002.1 - 4.8e-07 29.9 2.3 6.1e-07 29.6 0.6 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIR67002.1 - 2.7e-06 26.9 0.3 0.00093 18.5 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain ApbA PF02558.16 KIR67002.1 - 3.7e-05 23.4 0.3 7.5e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIR67002.1 - 6.6e-05 22.3 0.1 0.03 13.6 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIR67002.1 - 0.0015 18.1 0.4 0.003 17.2 0.4 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 KIR67002.1 - 0.0048 16.3 1.2 0.9 8.8 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIR67002.1 - 0.0076 15.6 0.1 3.7 6.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KIR67002.1 - 0.012 15.6 3.1 1.9 8.4 0.3 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KIR67002.1 - 0.015 15.2 0.4 0.026 14.4 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIR67002.1 - 0.024 13.9 0.4 0.051 12.9 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.6 KIR67002.1 - 0.035 14.1 1.1 1.1 9.2 0.1 2.8 3 1 0 3 3 3 0 Glycosyltransferase Family 4 GIDA PF01134.22 KIR67002.1 - 0.072 12.2 1.7 0.18 10.8 1.6 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 KIR67002.1 - 0.15 11.4 1.2 0.23 10.8 1.2 1.3 1 0 0 1 1 1 0 ThiF family DUF305 PF03713.13 KIR67003.1 - 2.7e-21 76.3 0.5 3.7e-21 75.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 KIR67003.1 - 0.0046 17.2 0.1 0.079 13.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4142) HATPase_c_2 PF13581.6 KIR67004.1 - 2.2e-16 60.0 0.2 2.7e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 KIR67004.1 - 5.1e-05 23.8 0.0 0.00015 22.2 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 KIR67005.1 - 2.1e-72 239.4 43.6 2.4e-09 37.4 0.1 11.4 10 1 1 11 11 9 8 HAMP domain Response_reg PF00072.24 KIR67005.1 - 1.6e-31 108.8 0.4 1.3e-25 89.7 0.5 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 KIR67005.1 - 1.7e-28 99.4 0.0 4.7e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KIR67005.1 - 4.7e-18 65.8 0.4 1.8e-17 64.0 0.4 2.1 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KIR67005.1 - 5.4e-17 61.6 0.5 5.4e-17 61.6 0.5 3.4 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 KIR67005.1 - 2.3e-10 40.6 50.3 0.045 14.0 0.9 10.9 5 4 3 9 9 9 5 Bacterial protein of unknown function (DUF948) DUF1759 PF03564.15 KIR67005.1 - 3.5e-07 30.3 1.4 4.9 7.1 0.0 6.6 7 0 0 7 7 7 1 Protein of unknown function (DUF1759) Laminin_II PF06009.12 KIR67005.1 - 4.1e-07 30.1 40.6 0.046 13.7 0.6 8.3 8 0 0 8 8 8 3 Laminin Domain II GAF PF01590.26 KIR67005.1 - 1.5e-06 28.9 0.1 4.4e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 GAF domain PseudoU_synth_1 PF01416.20 KIR67005.1 - 5.5e-06 26.8 6.6 24 5.4 0.0 7.2 6 1 0 7 7 7 0 tRNA pseudouridine synthase SpoIIID PF12116.8 KIR67005.1 - 2.2e-05 24.4 0.1 84 3.4 0.0 6.9 7 0 0 7 7 7 0 Stage III sporulation protein D GAF_3 PF13492.6 KIR67005.1 - 3e-05 24.4 0.1 0.00011 22.6 0.1 2.0 1 0 0 1 1 1 1 GAF domain DUF4279 PF14106.6 KIR67005.1 - 6e-05 23.2 0.0 41 4.4 0.0 6.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4279) UDPG_MGDP_dh PF00984.19 KIR67005.1 - 0.00011 22.4 0.0 94 3.3 0.0 7.0 7 0 0 7 7 7 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF4795 PF16043.5 KIR67005.1 - 0.00018 21.2 16.6 0.1 12.2 4.1 5.7 3 2 0 5 5 5 1 Domain of unknown function (DUF4795) UPF0184 PF03670.13 KIR67005.1 - 0.0002 21.6 8.9 47 4.5 0.0 7.4 8 0 0 8 8 6 0 Uncharacterised protein family (UPF0184) CMD PF02627.20 KIR67005.1 - 0.0005 20.1 11.4 13 5.9 0.0 7.3 7 0 0 7 7 7 0 Carboxymuconolactone decarboxylase family OmpH PF03938.14 KIR67005.1 - 0.00075 19.9 6.4 0.0039 17.5 6.4 2.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) GatB_Yqey PF02637.18 KIR67005.1 - 0.0052 16.7 11.9 4.3 7.2 0.0 5.9 7 0 0 7 7 7 1 GatB domain DUF3552 PF12072.8 KIR67005.1 - 0.0053 16.2 10.9 0.0053 16.2 10.9 3.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3552) Myb_DNA-bind_5 PF13873.6 KIR67005.1 - 0.0094 16.0 4.0 14 5.9 0.0 6.2 7 0 0 7 7 6 0 Myb/SANT-like DNA-binding domain Anillin_N PF16018.5 KIR67005.1 - 0.019 15.5 11.8 5.6 7.6 0.0 6.4 7 0 0 7 7 6 0 Anillin N-terminus YscO-like PF16789.5 KIR67005.1 - 0.058 13.4 3.7 0.16 12.0 3.7 1.8 1 0 0 1 1 1 0 YscO-like protein Fez1 PF06818.15 KIR67005.1 - 0.062 13.7 13.2 0.083 13.3 2.5 4.1 3 1 0 3 3 3 0 Fez1 Atg14 PF10186.9 KIR67005.1 - 0.085 11.9 6.0 0.2 10.7 6.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KIR67005.1 - 0.092 11.6 18.7 0.02 13.8 12.0 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein ERM PF00769.19 KIR67005.1 - 0.16 11.7 15.6 0.41 10.4 15.6 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 KIR67005.1 - 0.38 9.3 14.3 6.5 5.3 0.1 3.7 3 1 1 4 4 4 0 AAA domain WXG100 PF06013.12 KIR67005.1 - 0.6 10.4 37.7 0.77 10.0 0.1 10.0 6 2 6 12 12 12 0 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 KIR67005.1 - 2.1 8.5 12.1 1.9 8.7 8.8 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Lipoprotein_7 PF01540.16 KIR67005.1 - 3.2 7.0 9.0 2.2 7.5 1.3 3.8 3 1 1 4 4 4 0 Adhesin lipoprotein Spectrin PF00435.21 KIR67005.1 - 3.2 8.3 13.3 20 5.7 7.3 4.5 4 2 1 5 5 4 0 Spectrin repeat DUF3584 PF12128.8 KIR67005.1 - 3.7 4.9 24.0 2.4 5.6 0.1 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KIR67005.1 - 5.2 6.4 14.8 0.39 10.1 6.6 3.0 3 1 0 3 3 3 0 Golgin subfamily A member 5 DUF4200 PF13863.6 KIR67005.1 - 8.4 6.8 20.6 8.8e+02 0.3 0.0 5.8 6 1 0 6 6 6 0 Domain of unknown function (DUF4200) DUF4337 PF14235.6 KIR67005.1 - 9.4 6.3 8.9 19 5.4 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GerE PF00196.19 KIR67006.1 - 1.4e-17 63.0 0.0 2.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 KIR67006.1 - 9e-13 48.4 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 KIR67006.1 - 7.2e-05 22.4 0.0 0.0002 21.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR67006.1 - 0.00031 20.2 0.2 0.00068 19.1 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 KIR67006.1 - 0.0019 17.9 1.0 0.024 14.5 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KIR67006.1 - 0.0023 18.0 0.3 0.0078 16.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KIR67006.1 - 0.0069 16.2 0.1 0.022 14.6 0.1 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain TadZ_N PF16968.5 KIR67006.1 - 0.013 15.2 1.6 0.013 15.2 1.6 1.5 2 0 0 2 2 2 0 Pilus assembly protein TadZ N-terminal HTH_38 PF13936.6 KIR67006.1 - 0.02 14.6 0.1 0.054 13.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 KIR67006.1 - 0.029 14.4 1.3 0.055 13.5 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.6 KIR67006.1 - 0.034 14.8 0.9 2.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.6 KIR67006.1 - 0.039 14.4 0.1 0.095 13.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KIR67006.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 KIR67006.1 - 0.1 12.4 0.9 5.3 6.9 0.3 3.2 2 1 0 2 2 2 0 HTH DNA binding domain GerE PF00196.19 KIR67007.1 - 9.5e-14 50.7 0.0 1.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF742 PF05331.11 KIR67007.1 - 0.0012 18.6 1.1 0.003 17.4 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF742) Sigma70_r4_2 PF08281.12 KIR67007.1 - 0.0075 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KIR67007.1 - 0.04 13.4 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 KIR67007.1 - 0.085 13.3 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Response_reg PF00072.24 KIR67007.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain HTH_30 PF13556.6 KIR67007.1 - 0.61 9.9 2.6 0.36 10.7 0.3 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain ABC_tran PF00005.27 KIR67008.1 - 3.9e-22 79.2 0.0 7.6e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR67008.1 - 0.00032 20.6 0.1 0.76 9.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR67008.1 - 0.00037 20.0 0.0 0.054 12.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIR67008.1 - 0.00085 19.7 0.4 0.0032 17.9 0.4 2.0 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KIR67008.1 - 0.0027 17.1 0.6 0.0058 16.0 0.6 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 KIR67008.1 - 0.006 16.7 0.3 0.01 15.9 0.3 1.2 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KIR67008.1 - 0.0071 16.6 0.1 0.03 14.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR67008.1 - 0.0079 15.9 0.2 0.02 14.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_membrane PF00664.23 KIR67008.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region RsgA_GTPase PF03193.16 KIR67008.1 - 0.031 14.2 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KIR67008.1 - 0.12 12.5 0.3 0.31 11.2 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIR67008.1 - 0.14 12.2 0.2 0.62 10.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIR67008.1 - 0.2 11.4 1.2 0.56 9.9 0.2 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KIR67008.1 - 0.24 11.0 6.6 0.13 11.9 0.2 3.0 2 1 1 3 3 3 0 AAA domain VWA_CoxE PF05762.14 KIR67009.1 - 7e-28 97.5 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 KIR67009.1 - 0.014 16.0 0.0 0.037 14.7 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain MarR PF01047.22 KIR67010.1 - 4.5e-14 52.1 0.0 1.8e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 KIR67010.1 - 7.4e-13 48.2 2.2 7.4e-13 48.2 2.2 2.3 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 KIR67010.1 - 5.6e-09 36.4 0.2 1.2e-08 35.3 0.1 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 KIR67010.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KIR67010.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 KIR67010.1 - 0.018 14.8 1.4 0.018 14.8 1.4 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain FtsK_gamma PF09397.10 KIR67010.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain HTH_Crp_2 PF13545.6 KIR67010.1 - 0.21 11.6 2.6 0.98 9.5 0.8 2.5 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain DivIVA PF05103.13 KIR67011.1 - 1.9e-05 24.8 0.0 2.2e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 DivIVA protein HxlR PF01638.17 KIR67012.1 - 2.9e-22 78.3 0.2 3.6e-22 78.0 0.2 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 KIR67012.1 - 0.0021 18.1 0.1 0.0035 17.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KIR67012.1 - 0.0042 16.9 0.2 0.0066 16.3 0.2 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KIR67012.1 - 0.041 13.8 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 MarR family PadR PF03551.14 KIR67012.1 - 0.042 13.8 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RmlD_sub_bind PF04321.17 KIR67013.1 - 5.8e-34 117.5 0.0 6.8e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIR67013.1 - 2.8e-17 63.0 0.0 3.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIR67013.1 - 6.1e-08 32.8 1.8 9.1e-08 32.2 0.0 2.0 2 1 1 3 3 3 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIR67013.1 - 4e-06 26.5 0.0 1.4e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KIR67013.1 - 0.019 15.5 0.0 0.084 13.5 0.0 2.0 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KIR67013.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KIR67013.1 - 0.023 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.12 KIR67013.1 - 0.038 13.2 0.0 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein LpxI_N PF17930.1 KIR67013.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 LpxI N-terminal domain NUDIX PF00293.28 KIR67014.1 - 7.8e-07 29.2 0.1 1e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 KIR67015.1 - 8.9e-26 90.6 75.1 3.7e-19 68.9 44.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIR67015.1 - 0.059 12.2 12.7 0.16 10.8 8.6 2.1 1 1 1 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 KIR67015.1 - 1.9 7.2 25.3 0.042 12.7 11.9 2.8 3 0 0 3 3 3 0 Sugar (and other) transporter MFS_3 PF05977.13 KIR67015.1 - 6.1 5.1 34.7 27 3.0 20.1 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector Barstar PF01337.18 KIR67016.1 - 1e-13 51.1 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Barstar (barnase inhibitor) AAA_22 PF13401.6 KIR67016.1 - 0.1 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain PmoA PF14100.6 KIR67017.1 - 2.2e-71 240.5 0.9 2.5e-71 240.4 0.9 1.0 1 0 0 1 1 1 1 Methane oxygenase PmoA AP_endonuc_2 PF01261.24 KIR67018.1 - 3e-29 102.0 0.3 4.7e-29 101.3 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MoCF_biosynth PF00994.24 KIR67018.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Probable molybdopterin binding domain UxuA PF03786.13 KIR67018.1 - 0.2 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) TP_methylase PF00590.20 KIR67019.1 - 5.9e-47 160.3 3.2 7.5e-47 160.0 3.2 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiX PF01903.17 KIR67020.1 - 1.5e-48 163.6 0.0 5.1e-23 81.4 0.0 2.9 3 0 0 3 3 3 2 CbiX TP_methylase PF00590.20 KIR67020.1 - 1.1e-45 156.2 8.5 2.5e-45 155.1 8.5 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiK PF06180.11 KIR67020.1 - 0.00035 20.0 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Cobalt chelatase (CbiK) Radical_SAM PF04055.21 KIR67020.1 - 0.034 14.5 0.0 0.47 10.8 0.0 2.6 2 2 0 2 2 2 0 Radical SAM superfamily Ferrochelatase PF00762.19 KIR67020.1 - 0.056 12.5 0.0 0.79 8.7 0.0 2.1 1 1 0 1 1 1 0 Ferrochelatase SelP_N PF04592.14 KIR67020.1 - 2.6 7.4 7.5 3.9 6.8 7.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4334 PF14232.6 KIR67021.1 - 1.8e-26 91.8 0.5 3.3e-26 91.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 KIR67021.1 - 5.6e-25 87.2 0.4 8.9e-25 86.5 0.4 1.3 1 0 0 1 1 1 1 GXWXG protein TPR_2 PF07719.17 KIR67022.1 - 2.5e-26 89.6 22.5 6.1e-05 22.8 0.0 9.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIR67022.1 - 1.2e-24 85.1 4.1 0.00029 20.5 0.0 7.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KIR67022.1 - 6.1e-20 70.1 9.2 0.0055 17.0 0.0 8.4 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 KIR67022.1 - 2.1e-17 63.0 59.0 1.8e-08 34.4 6.9 6.7 3 1 4 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KIR67022.1 - 3.8e-17 61.7 7.4 7.3e-06 25.6 0.3 5.7 3 2 3 6 6 6 3 TPR repeat TPR_12 PF13424.6 KIR67022.1 - 2.8e-16 59.5 42.3 0.00028 21.1 1.8 8.0 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 KIR67022.1 - 2.2e-13 50.6 90.6 1.8e-06 28.5 4.5 8.2 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIR67022.1 - 9.8e-12 44.1 0.0 0.46 10.8 0.0 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIR67022.1 - 1.4e-11 44.7 39.2 0.00013 22.4 1.4 7.2 4 3 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIR67022.1 - 3.8e-09 36.6 87.2 0.0046 17.7 0.8 11.4 5 2 7 12 12 11 6 Tetratricopeptide repeat NARP1 PF12569.8 KIR67022.1 - 5.7e-05 22.2 0.1 0.017 14.1 0.1 2.8 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 KIR67022.1 - 8.1e-05 22.4 22.6 0.93 9.7 0.1 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIR67022.1 - 0.00015 22.0 6.8 0.0061 17.1 3.2 12.4 12 1 0 12 12 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 KIR67022.1 - 0.00024 21.5 25.2 0.58 10.9 0.1 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat Sel1 PF08238.12 KIR67022.1 - 0.0049 17.5 3.5 0.022 15.5 0.7 3.5 3 0 0 3 3 3 1 Sel1 repeat AAA_16 PF13191.6 KIR67022.1 - 0.016 15.6 0.0 0.016 15.6 0.0 3.5 4 1 0 4 4 4 0 AAA ATPase domain TPR_10 PF13374.6 KIR67022.1 - 0.031 14.1 54.3 0.11 12.4 0.4 9.6 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF4248 PF14053.6 KIR67022.1 - 0.59 10.2 2.5 40 4.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) TPR_20 PF14561.6 KIR67022.1 - 8.7 6.8 13.5 0.9 9.9 0.1 4.4 3 1 0 4 4 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KIR67023.1 - 2.4e-39 135.6 0.0 2.9e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIR67023.1 - 1.2e-05 24.1 0.0 1.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KIR67023.1 - 0.02 14.2 0.0 0.042 13.1 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KIR67023.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_43 PF04616.14 KIR67024.1 - 5.9e-36 124.3 5.2 8.5e-36 123.7 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_2 PF00553.19 KIR67024.1 - 2.1e-32 111.4 13.5 2.1e-32 111.4 13.5 2.8 2 0 0 2 2 2 1 Cellulose binding domain GH43_C2 PF17851.1 KIR67024.1 - 6.6e-30 104.3 0.1 1.5e-29 103.2 0.1 1.6 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SBP_bac_3 PF00497.20 KIR67025.1 - 3.8e-27 95.2 0.0 7.7e-27 94.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_5 PF00496.22 KIR67026.1 - 4.3e-68 230.0 3.7 5.5e-68 229.6 3.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle NMT1 PF09084.11 KIR67026.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 NMT1/THI5 like EAL PF00563.20 KIR67026.1 - 0.057 12.9 0.0 25 4.3 0.0 3.1 3 0 0 3 3 3 0 EAL domain BPD_transp_1 PF00528.22 KIR67027.1 - 1.3e-31 109.8 13.8 1.3e-31 109.8 13.8 1.7 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MFS_1 PF07690.16 KIR67028.1 - 1.4e-38 132.8 47.6 1.4e-38 132.8 47.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIR67028.1 - 2.9e-09 36.3 10.2 2.9e-09 36.3 10.2 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter BPD_transp_1 PF00528.22 KIR67029.1 - 9.9e-09 35.2 26.7 1.6e-08 34.5 23.0 2.6 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component AMO PF02461.16 KIR67029.1 - 0.011 15.5 4.0 0.011 15.5 4.0 2.1 2 1 0 2 2 2 0 Ammonia monooxygenase Amidohydro_1 PF01979.20 KIR67030.1 - 7.7e-30 104.4 0.0 1e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIR67030.1 - 8.4e-14 51.9 8.3 1.4e-08 34.6 3.9 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 KIR67030.1 - 0.00072 19.4 3.4 0.0015 18.4 3.4 1.6 1 0 0 1 1 1 1 Amidohydrolase CoA_transf_3 PF02515.17 KIR67031.1 - 1.3e-117 393.1 0.0 1.4e-117 392.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DDE_Tnp_4 PF13359.6 KIR67032.1 - 1.4e-16 60.5 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 KIR67032.1 - 4.7e-15 55.0 0.0 9.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KIR67032.1 - 3.7e-11 43.1 0.3 5.6e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain SpoIIID PF12116.8 KIR67032.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Stage III sporulation protein D HTH_38 PF13936.6 KIR67032.1 - 0.06 13.1 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 KIR67032.1 - 0.088 13.4 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DUF2470 PF10615.9 KIR67033.1 - 2.8e-05 24.7 0.0 5.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) GDE_N_bis PF14742.6 KIR67034.1 - 1.9e-38 132.0 1.1 3.1e-38 131.3 1.1 1.3 1 0 0 1 1 1 1 N-terminal domain of (some) glycogen debranching enzymes GDE_C PF06202.14 KIR67034.1 - 0.01 14.8 0.0 0.031 13.2 0.0 1.7 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KIR67034.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Trehalase ABC_tran PF00005.27 KIR67035.1 - 5.4e-46 156.5 0.0 7.3e-29 101.0 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIR67035.1 - 4.7e-16 59.5 0.1 0.0001 22.2 0.0 3.1 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIR67035.1 - 0.0011 19.2 1.4 0.026 14.8 1.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIR67035.1 - 0.0024 17.6 0.1 0.0062 16.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIR67035.1 - 0.0035 17.7 0.5 0.0035 17.7 0.5 2.1 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIR67035.1 - 0.0045 16.9 0.1 0.0095 15.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 KIR67035.1 - 0.0046 17.1 0.1 0.031 14.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIR67035.1 - 0.0094 15.4 0.0 0.3 10.5 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIR67035.1 - 0.01 16.4 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KIR67035.1 - 0.015 15.5 1.1 7.8 6.8 0.2 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AFG1_ATPase PF03969.16 KIR67035.1 - 0.023 13.6 0.0 2.8 6.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Zeta_toxin PF06414.12 KIR67035.1 - 0.025 13.9 0.2 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KIR67035.1 - 0.026 14.2 3.3 0.69 9.6 3.3 2.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KIR67035.1 - 0.033 13.9 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KIR67035.1 - 0.098 12.2 8.9 2.1 7.9 4.4 3.4 2 1 0 2 2 2 0 AAA domain DLIC PF05783.11 KIR67035.1 - 0.15 10.8 0.1 0.23 10.2 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ABC_ATPase PF09818.9 KIR67035.1 - 0.27 10.0 2.0 3.7 6.2 0.1 3.0 4 0 0 4 4 4 0 Predicted ATPase of the ABC class AAA_10 PF12846.7 KIR67035.1 - 0.28 10.0 0.2 2.3 7.0 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain DeoC PF01791.9 KIR67036.1 - 0.00017 21.3 0.9 0.00021 21.0 0.9 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase UTRA PF07702.13 KIR67037.1 - 1.4e-36 125.5 0.1 3.3e-36 124.2 0.0 1.6 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 KIR67037.1 - 1.7e-16 59.6 0.3 3.3e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 KIR67037.1 - 0.00011 21.9 1.7 0.0002 21.1 0.3 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain AbiEi_4 PF13338.6 KIR67037.1 - 0.00012 22.2 0.4 0.00063 19.9 0.2 2.3 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin HTH_24 PF13412.6 KIR67037.1 - 0.0002 20.8 0.4 0.00071 19.1 0.1 2.2 3 0 0 3 3 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KIR67037.1 - 0.00025 21.1 1.6 0.0016 18.4 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KIR67037.1 - 0.00035 20.5 0.0 0.0017 18.3 0.0 2.2 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 KIR67037.1 - 0.00072 19.3 0.1 0.0022 17.7 0.1 1.8 2 0 0 2 2 1 1 DeoR-like helix-turn-helix domain HTH_41 PF14502.6 KIR67037.1 - 0.00072 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIR67037.1 - 0.0016 18.1 0.3 0.14 12.0 0.2 3.0 2 1 0 2 2 2 1 Homeodomain-like domain Rrf2 PF02082.20 KIR67037.1 - 0.0022 18.3 0.0 0.0096 16.3 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator HTH_11 PF08279.12 KIR67037.1 - 0.0038 17.1 0.2 0.011 15.7 0.1 1.8 2 0 0 2 2 1 1 HTH domain MarR_2 PF12802.7 KIR67037.1 - 0.0042 16.9 0.3 0.022 14.6 0.1 2.3 2 0 0 2 2 2 1 MarR family PaaX PF07848.12 KIR67037.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 PaaX-like protein HTH_31 PF13560.6 KIR67037.1 - 0.016 15.5 3.8 0.21 12.0 0.6 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 KIR67037.1 - 0.036 14.2 1.2 0.065 13.4 0.2 2.0 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_5 PF01022.20 KIR67037.1 - 0.039 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_8 PF02954.19 KIR67037.1 - 0.1 12.4 0.1 0.31 10.9 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_36 PF13730.6 KIR67037.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Ring_hydroxyl_A PF00848.19 KIR67038.1 - 7.7e-34 117.5 0.5 1.6e-33 116.5 0.5 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KIR67038.1 - 7.1e-15 54.7 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Trans_reg_C PF00486.28 KIR67039.1 - 1.4e-26 92.4 0.1 5e-26 90.6 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 KIR67039.1 - 3.7e-25 88.3 0.0 6.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HlyD_D23 PF16576.5 KIR67040.1 - 1.4e-14 53.8 1.8 1.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KIR67040.1 - 1.9e-11 44.6 5.0 4.9e-07 30.4 0.1 3.8 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KIR67040.1 - 2.3e-09 36.9 2.7 1.4e-08 34.4 0.4 2.9 2 1 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 KIR67040.1 - 0.00032 20.5 0.2 0.0098 15.7 0.0 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme DUF4398 PF14346.6 KIR67040.1 - 0.01 16.4 9.1 0.01 16.4 9.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) PTS_EIIA_1 PF00358.20 KIR67040.1 - 0.018 14.8 0.4 0.24 11.2 0.0 2.6 2 1 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 KIR67040.1 - 0.019 14.9 0.3 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 KIR67040.1 - 0.03 14.5 4.4 0.27 11.4 0.3 2.7 2 0 0 2 2 2 0 Peptidase family M23 Peptidase_M73 PF12389.8 KIR67040.1 - 0.15 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase OEP PF02321.18 KIR67040.1 - 0.52 10.1 5.1 0.47 10.2 2.9 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein HlyD PF00529.20 KIR67040.1 - 5.7 6.9 31.5 9.6e+02 -0.2 31.4 3.2 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS ABC_tran PF00005.27 KIR67041.1 - 2.7e-29 102.4 0.0 3.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIR67041.1 - 4.7e-05 23.4 0.9 0.072 12.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIR67041.1 - 6.9e-05 22.4 0.1 0.065 12.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIR67041.1 - 0.00028 20.6 0.5 0.00056 19.6 0.5 1.6 1 1 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIR67041.1 - 0.0038 17.1 0.1 0.0085 16.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase MeaB PF03308.16 KIR67041.1 - 0.027 13.4 0.1 0.054 12.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KIR67041.1 - 0.035 14.2 0.1 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KIR67041.1 - 0.043 13.9 0.3 0.071 13.2 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 KIR67041.1 - 0.082 13.1 2.4 4.8 7.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIR67041.1 - 0.14 11.9 0.0 0.76 9.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIR67041.1 - 0.15 11.8 0.2 1.1 8.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIR67041.1 - 0.39 11.1 3.8 1.6 9.1 3.8 2.1 1 1 0 1 1 1 0 AAA ATPase domain HlyD PF00529.20 KIR67042.1 - 0.048 13.5 4.8 0.43 10.5 1.8 2.5 2 0 0 2 2 2 0 HlyD membrane-fusion protein of T1SS tRNA_anti-like PF12869.7 KIR67042.1 - 0.059 13.0 0.6 0.1 12.2 0.6 1.4 1 0 0 1 1 1 0 tRNA_anti-like Myosin_N PF02736.19 KIR67042.1 - 6.2 6.7 7.8 6.7 6.6 4.8 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Cellulase PF00150.18 KIR67043.1 - 7.4e-56 189.6 0.2 1.1e-55 189.0 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM46 PF18448.1 KIR67043.1 - 6e-53 177.6 4.0 6e-53 177.6 4.0 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CBM_2 PF00553.19 KIR67043.1 - 2.4e-32 111.2 12.4 2.4e-32 111.2 12.4 3.3 4 0 0 4 4 4 1 Cellulose binding domain CBM_X2 PF03442.14 KIR67043.1 - 3.3e-20 72.0 2.4 1.2e-17 63.8 0.5 2.9 2 0 0 2 2 2 2 Carbohydrate binding domain X2 ChitinaseA_N PF08329.10 KIR67043.1 - 0.057 13.1 0.1 3.3 7.3 0.0 3.0 2 0 0 2 2 2 0 Chitinase A, N-terminal domain Glyco_hydro_35 PF01301.19 KIR67043.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 ABC_tran PF00005.27 KIR67045.1 - 3.5e-27 95.6 0.0 4.6e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KIR67045.1 - 6.7e-19 68.2 0.3 1.2e-18 67.4 0.3 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KIR67045.1 - 1.2e-06 28.6 0.8 2e-05 24.6 0.1 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TetR_C_11 PF16859.5 KIR67045.1 - 0.0057 16.9 3.4 0.0057 16.9 3.4 3.5 4 0 0 4 4 4 1 Tetracyclin repressor-like, C-terminal domain Mg_chelatase PF01078.21 KIR67045.1 - 0.0058 16.0 0.1 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIR67045.1 - 0.0065 16.7 0.4 0.088 13.1 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIR67045.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KIR67045.1 - 0.013 15.6 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 KIR67045.1 - 0.022 15.1 0.9 0.052 13.9 0.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KIR67045.1 - 0.024 14.1 0.0 0.27 10.6 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIR67045.1 - 0.024 15.1 0.0 0.076 13.4 0.0 1.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIR67045.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KIR67045.1 - 0.19 11.1 0.0 20 4.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Peptidase_M24 PF00557.24 KIR67046.1 - 7.2e-40 136.9 0.1 1e-39 136.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KIR67046.1 - 4.3e-10 40.4 0.0 9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Micromonospora_carbonacea_JXNU-1-ASM87622v1/GCA_000876225.1_ASM87622v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Micromonospora_carbonacea_JXNU-1-ASM87622v1/GCA_000876225.1_ASM87622v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Micromonospora_carbonacea_JXNU-1-ASM87622v1/GCA_000876225.1_ASM87622v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Micromonospora_carbonacea_JXNU-1-ASM87622v1/GCA_000876225.1_ASM87622v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:33:33 2019 # [ok]