# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- QueC PF06508.13 AFI82863.1 - 1.5e-79 266.4 0.0 1.7e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AFI82863.1 - 2.3e-06 27.5 0.0 2.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 AFI82863.1 - 0.0037 16.9 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 2 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 AFI82863.1 - 0.0089 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.20 AFI82863.1 - 0.013 15.3 0.0 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 PP-loop family tRNA_Me_trans PF03054.16 AFI82863.1 - 0.022 13.5 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase 2-Hacid_dh PF00389.30 AFI82863.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Radical_SAM PF04055.21 AFI82864.1 - 1.4e-13 51.6 0.1 2e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AFI82864.1 - 1.1e-09 38.4 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AFI82864.1 - 1.4e-06 28.6 0.1 2.2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain TolA_bind_tri PF16331.5 AFI82865.1 - 7.9e-23 80.3 15.6 7.9e-23 80.3 15.6 1.8 2 0 0 2 2 1 1 TolA binding protein trimerisation TPR_6 PF13174.6 AFI82865.1 - 2.9e-21 74.6 1.3 4.2e-07 30.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat YfiO PF13525.6 AFI82865.1 - 1.1e-11 44.8 1.1 3.9e-11 43.1 1.1 1.8 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_2 PF07719.17 AFI82865.1 - 1.2e-11 43.7 0.1 5.9e-05 22.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AFI82865.1 - 1.5e-10 41.6 0.2 0.00018 22.1 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AFI82865.1 - 8.1e-09 34.9 0.1 0.00015 21.5 0.0 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AFI82865.1 - 6.8e-08 32.7 0.1 0.12 13.3 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 AFI82865.1 - 8.6e-07 28.9 3.2 1.6e-05 24.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 AFI82865.1 - 1.5e-05 25.4 7.4 0.0056 17.2 0.3 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AFI82865.1 - 1.8e-05 25.0 0.1 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AFI82865.1 - 8.8e-05 22.4 0.0 0.38 11.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_18 PF13512.6 AFI82865.1 - 0.00017 21.7 4.6 0.00037 20.6 1.4 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 AFI82865.1 - 0.00026 21.1 0.2 0.0042 17.2 0.0 2.9 2 2 0 2 2 2 1 Tetratricopeptide repeat CENP-H PF05837.12 AFI82865.1 - 0.0033 17.8 3.9 0.13 12.7 1.5 2.6 2 0 0 2 2 2 1 Centromere protein H (CENP-H) UPF0242 PF06785.11 AFI82865.1 - 0.0047 17.0 4.1 0.008 16.3 4.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4446 PF14584.6 AFI82865.1 - 0.0097 15.9 0.6 0.024 14.6 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) DHR10 PF18595.1 AFI82865.1 - 0.01 15.9 8.6 0.026 14.6 8.6 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain GAS PF13851.6 AFI82865.1 - 0.028 13.8 6.2 0.06 12.7 3.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ANAPC3 PF12895.7 AFI82865.1 - 0.051 13.8 0.3 0.37 11.1 0.2 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2362 PF10154.9 AFI82865.1 - 0.051 12.5 3.5 0.071 12.0 3.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Speriolin_N PF15058.6 AFI82865.1 - 0.052 13.6 0.7 0.1 12.7 0.5 1.6 2 0 0 2 2 1 0 Speriolin N terminus HemY_N PF07219.13 AFI82865.1 - 0.052 13.7 0.1 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus FliD_C PF07195.12 AFI82865.1 - 0.062 12.7 3.9 0.042 13.3 2.1 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF465 PF04325.13 AFI82865.1 - 0.082 13.0 1.9 3.9 7.6 0.0 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF465) MCC-bdg_PDZ PF10506.9 AFI82865.1 - 0.087 12.8 5.2 1.8 8.7 2.1 3.0 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome LytR_C PF13399.6 AFI82865.1 - 0.1 13.6 2.2 0.85 10.7 0.2 2.6 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Phage_GP20 PF06810.11 AFI82865.1 - 0.12 12.2 3.5 0.22 11.3 2.9 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 AFI82865.1 - 0.24 11.5 3.2 0.17 12.0 0.8 2.1 2 0 0 2 2 1 0 bZIP transcription factor FUSC PF04632.12 AFI82865.1 - 0.25 9.9 1.9 0.32 9.5 1.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 AFI82865.1 - 0.54 10.7 10.8 1.4 9.5 9.7 2.2 1 1 0 1 1 1 0 Cell division protein ZapB Spc24 PF08286.11 AFI82865.1 - 1.1 9.6 4.9 3.2 8.1 4.9 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 GIT_CC PF16559.5 AFI82865.1 - 1.3 9.0 6.5 0.62 10.0 3.3 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 AFI82865.1 - 2.2 9.0 5.2 4.2 8.1 5.2 1.6 1 1 0 1 1 1 0 Initiation control protein YabA OmpA PF00691.20 AFI82866.1 - 1.6e-19 70.1 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 OmpA family PD40 PF07676.12 AFI82867.1 - 5.4e-40 134.5 5.7 1.5e-10 40.8 0.1 6.4 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat TolB_N PF04052.13 AFI82867.1 - 1.4e-32 112.0 0.0 3.8e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 TolB amino-terminal domain DPPIV_N PF00930.21 AFI82867.1 - 1.7e-11 43.5 0.0 0.00042 19.2 0.0 3.9 1 1 3 4 4 4 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.6 AFI82867.1 - 1.9e-05 23.5 0.0 0.35 9.5 0.0 4.1 2 2 2 5 5 5 2 Oligogalacturonate lyase Gmad1 PF10647.9 AFI82867.1 - 7.1e-05 22.7 0.2 1.3 8.7 0.0 3.1 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain SGL PF08450.12 AFI82867.1 - 0.0019 17.8 0.0 0.05 13.2 0.0 2.6 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 AFI82867.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Esterase-like activity of phytase Peptidase_S9_N PF02897.15 AFI82867.1 - 0.044 12.6 0.0 0.34 9.6 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 AFI82867.1 - 4.6 7.0 9.1 1e+02 2.7 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TonB_2 PF13103.6 AFI82868.1 - 2.2e-14 53.5 0.0 4.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 TonB C terminal TonB_C PF03544.14 AFI82868.1 - 3.8e-08 33.6 0.0 1.3e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TolA PF06519.11 AFI82868.1 - 4.5e-07 30.0 0.0 9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 TolA C-terminal TFIIA PF03153.13 AFI82868.1 - 0.45 10.5 29.1 0.53 10.2 29.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ExbD PF02472.16 AFI82869.1 - 3.1e-29 101.8 0.1 3.6e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 AFI82870.1 - 1.5e-41 141.1 0.1 2.2e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family 4HBT PF03061.22 AFI82871.1 - 1.6e-18 66.8 0.0 2.3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AFI82871.1 - 7.8e-14 52.2 0.0 8.9e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AFI82871.1 - 0.0036 16.6 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase RuvB_N PF05496.12 AFI82872.1 - 2e-81 271.4 0.0 2.7e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AFI82872.1 - 9.4e-32 108.6 1.6 1.8e-31 107.7 1.6 1.5 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AFI82872.1 - 4.9e-27 93.6 0.0 9e-27 92.8 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AFI82872.1 - 9e-19 68.2 0.0 1.7e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI82872.1 - 1e-07 32.0 0.1 0.0016 18.5 0.0 2.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AFI82872.1 - 3.6e-05 23.6 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI82872.1 - 0.0001 21.7 0.3 0.12 11.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AFI82872.1 - 0.00027 20.3 0.1 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 AFI82872.1 - 0.0003 20.5 0.0 0.84 9.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 AFI82872.1 - 0.00059 20.1 0.2 0.082 13.2 0.0 2.5 1 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AFI82872.1 - 0.00093 19.2 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain DUF4129 PF13559.6 AFI82872.1 - 0.0058 16.9 0.7 0.038 14.3 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) AAA_16 PF13191.6 AFI82872.1 - 0.0059 17.0 0.1 0.19 12.1 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 AFI82872.1 - 0.0068 17.0 0.0 0.016 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AFI82872.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AFI82872.1 - 0.018 14.9 0.1 0.16 11.9 0.0 2.5 3 0 0 3 3 3 0 NTPase Bac_DnaA PF00308.18 AFI82872.1 - 0.049 13.5 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 AFI82872.1 - 0.056 13.8 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 AFI82872.1 - 0.066 13.1 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 AFI82872.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 AFI82872.1 - 0.081 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 AFI82872.1 - 0.098 13.0 0.6 1.5 9.2 0.1 2.3 1 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AFI82872.1 - 0.12 12.1 1.0 0.37 10.5 0.1 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 AFI82872.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 AFI82872.1 - 0.14 11.3 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 AFI82872.1 - 0.15 11.2 0.0 0.35 10.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 AFI82872.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AFI82872.1 - 0.26 11.0 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RuvA_N PF01330.21 AFI82873.1 - 3.3e-23 81.5 0.0 5.3e-22 77.7 0.0 2.4 2 0 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 AFI82873.1 - 3.6e-17 62.7 0.5 3.7e-16 59.5 0.2 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 AFI82873.1 - 2.2e-14 53.6 0.4 4e-14 52.8 0.4 1.4 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 AFI82873.1 - 3e-07 30.0 2.2 0.0026 17.5 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_8 PF14716.6 AFI82873.1 - 0.00033 21.0 0.1 0.059 13.7 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_3 PF12836.7 AFI82873.1 - 0.0025 18.1 1.1 0.088 13.1 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 AFI82873.1 - 0.003 17.8 0.1 0.058 13.7 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif Transposase_20 PF02371.16 AFI82873.1 - 0.0049 17.2 0.0 0.13 12.6 0.0 2.4 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family Ribosomal_S13 PF00416.22 AFI82873.1 - 0.011 16.1 0.1 2.9 8.3 0.0 2.6 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DUF3173 PF11372.8 AFI82873.1 - 0.034 14.0 0.6 0.45 10.4 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3173) 5_3_exonuc PF01367.20 AFI82873.1 - 0.067 13.8 0.2 2.1 9.0 0.0 2.4 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold RuvC PF02075.17 AFI82874.1 - 1.2e-53 181.0 0.7 1.4e-53 180.8 0.7 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC MCR_beta_N PF02783.15 AFI82874.1 - 0.07 12.8 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Transcrip_reg PF01709.20 AFI82875.1 - 5.5e-98 327.2 0.3 6.2e-98 327.0 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator CHASE PF03924.13 AFI82875.1 - 0.08 12.9 0.2 12 5.8 0.0 2.5 3 0 0 3 3 3 0 CHASE domain Aminotran_4 PF01063.19 AFI82876.1 - 2.9e-54 184.3 0.0 3.3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV GlnE PF03710.15 AFI82877.1 - 6.3e-167 553.2 0.5 2.4e-84 282.7 0.1 2.4 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AFI82877.1 - 5.7e-57 191.9 11.4 7.4e-45 152.6 2.8 3.4 3 0 0 3 3 3 2 GlnD PII-uridylyltransferase DUF2273 PF10031.9 AFI82878.1 - 0.081 13.0 1.8 0.081 13.0 1.8 1.9 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Leu_leader PF08054.11 AFI82878.1 - 0.2 11.3 1.8 0.37 10.4 1.8 1.5 1 0 0 1 1 1 0 Leucine operon leader peptide Cpn60_TCP1 PF00118.24 AFI82879.1 - 8.8e-97 324.8 16.8 1.5e-96 324.0 16.8 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2125 PF09898.9 AFI82879.1 - 0.026 14.2 0.7 0.026 14.2 0.7 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) Cpn10 PF00166.21 AFI82880.1 - 1.3e-34 118.1 0.2 1.4e-34 118.0 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit FxsA PF04186.13 AFI82881.1 - 2e-35 121.2 10.4 2.6e-35 120.9 10.4 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein Porin_O_P PF07396.11 AFI82882.1 - 7.2e-42 143.8 4.0 1.8e-41 142.5 4.0 1.5 1 1 0 1 1 1 1 Phosphate-selective porin O and P EAL PF00563.20 AFI82883.1 - 3e-52 177.5 0.0 4.5e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI82883.1 - 5.7e-17 61.9 0.1 2.1e-16 60.1 0.1 2.0 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CBS PF00571.28 AFI82883.1 - 0.02 15.3 0.0 2.9 8.4 0.0 2.6 2 0 0 2 2 2 0 CBS domain LMWPc PF01451.21 AFI82884.1 - 5.9e-19 68.9 0.0 7.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3_3 PF08239.11 AFI82885.1 - 5.2e-07 29.8 0.2 1.2e-06 28.7 0.0 1.6 2 0 0 2 2 1 1 Bacterial SH3 domain bZIP_1 PF00170.21 AFI82885.1 - 8.5e-05 22.6 11.9 0.0057 16.7 2.9 2.8 1 1 1 2 2 2 2 bZIP transcription factor Dynamitin PF04912.14 AFI82885.1 - 0.00019 20.9 5.5 0.00025 20.5 5.5 1.1 1 0 0 1 1 1 1 Dynamitin GAS PF13851.6 AFI82885.1 - 0.00022 20.7 14.3 0.0003 20.2 14.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 AFI82885.1 - 0.0045 16.6 0.6 0.0048 16.5 0.6 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit MAD PF05557.13 AFI82885.1 - 0.0046 15.4 9.0 0.006 15.0 9.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Rab5-bind PF09311.11 AFI82885.1 - 0.0093 15.4 7.3 0.016 14.6 6.9 1.5 2 0 0 2 2 1 1 Rabaptin-like protein Occludin_ELL PF07303.13 AFI82885.1 - 0.011 16.5 4.2 0.017 15.8 4.2 1.3 1 0 0 1 1 1 0 Occludin homology domain PKcGMP_CC PF16808.5 AFI82885.1 - 0.011 15.6 0.3 0.011 15.6 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 AFI82885.1 - 0.012 14.7 6.0 0.016 14.3 6.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 AFI82885.1 - 0.014 14.0 5.1 0.015 13.9 5.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF262 PF03235.14 AFI82885.1 - 0.015 15.5 0.4 0.018 15.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Cnn_1N PF07989.11 AFI82885.1 - 0.016 15.3 2.6 0.016 15.3 2.6 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF2353 PF09789.9 AFI82885.1 - 0.017 14.5 8.7 0.024 14.0 8.7 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 AFI82885.1 - 0.018 15.5 11.3 0.04 14.4 11.3 1.5 1 1 0 1 1 1 0 Fez1 RFX5_DNA_bdg PF14621.6 AFI82885.1 - 0.021 14.6 0.2 0.03 14.1 0.2 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain ZapB PF06005.12 AFI82885.1 - 0.024 15.0 17.7 0.36 11.3 6.4 2.3 1 1 1 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 AFI82885.1 - 0.025 12.5 0.6 0.027 12.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 AFI82885.1 - 0.038 13.8 11.6 0.084 12.7 11.6 1.6 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 AFI82885.1 - 0.039 13.2 5.0 0.049 12.9 5.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 AFI82885.1 - 0.04 14.5 5.0 0.04 14.5 5.0 2.2 1 1 1 2 2 2 0 SlyX TMF_TATA_bd PF12325.8 AFI82885.1 - 0.043 14.0 12.6 0.61 10.3 10.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4208 PF13907.6 AFI82885.1 - 0.053 14.0 1.6 0.088 13.2 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Sipho_Gp157 PF05565.11 AFI82885.1 - 0.057 13.4 1.2 0.057 13.4 1.2 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 CENP-F_leu_zip PF10473.9 AFI82885.1 - 0.062 13.3 11.5 0.11 12.5 11.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFP_35_N PF07334.13 AFI82885.1 - 0.067 13.3 8.1 0.45 10.6 2.3 2.6 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF812 PF05667.11 AFI82885.1 - 0.068 12.0 9.8 0.09 11.7 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 AFI82885.1 - 0.073 11.3 12.3 0.16 10.2 12.1 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 AFI82885.1 - 0.08 13.4 8.4 2.9 8.4 1.1 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Tho2 PF11262.8 AFI82885.1 - 0.09 12.0 5.8 0.12 11.6 5.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3584 PF12128.8 AFI82885.1 - 0.1 10.1 12.6 0.13 9.8 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 AFI82885.1 - 0.1 11.4 12.6 0.14 11.0 12.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LpxB PF02684.15 AFI82885.1 - 0.11 11.3 1.2 0.15 10.9 1.2 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Tropomyosin PF00261.20 AFI82885.1 - 0.13 11.6 12.4 1.7 8.0 11.8 1.9 1 1 0 1 1 1 0 Tropomyosin FapA PF03961.13 AFI82885.1 - 0.14 10.7 8.5 0.19 10.3 8.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 AFI82885.1 - 0.15 12.3 14.2 0.42 10.8 14.2 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 AFI82885.1 - 0.16 12.1 14.1 0.47 10.6 8.1 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase PCRF PF03462.18 AFI82885.1 - 0.16 11.8 4.2 0.28 11.0 4.2 1.4 1 0 0 1 1 1 0 PCRF domain HMMR_N PF15905.5 AFI82885.1 - 0.17 11.3 11.1 0.25 10.8 11.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CCCAP PF15964.5 AFI82885.1 - 0.19 10.0 11.4 0.27 9.5 4.3 2.0 1 1 1 2 2 2 0 Centrosomal colon cancer autoantigen protein family ADIP PF11559.8 AFI82885.1 - 0.21 11.6 14.6 0.8 9.8 14.5 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 AFI82885.1 - 0.24 11.5 14.6 0.8 9.8 5.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 AFI82885.1 - 0.25 12.0 10.9 3.7 8.2 1.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 AFI82885.1 - 0.27 10.5 13.9 0.17 11.1 9.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 AFI82885.1 - 0.31 11.6 15.5 0.79 10.3 15.1 1.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 AFI82885.1 - 0.33 11.4 8.0 0.56 10.7 8.0 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.15 AFI82885.1 - 0.34 10.7 17.7 0.29 10.9 2.1 3.3 1 1 2 3 3 3 0 Septum formation initiator Leu_zip PF15294.6 AFI82885.1 - 0.35 10.4 11.7 1.9 8.0 1.6 2.0 1 1 1 2 2 2 0 Leucine zipper Paralemmin PF03285.15 AFI82885.1 - 0.35 10.4 9.6 0.63 9.6 9.6 1.5 1 1 0 1 1 1 0 Paralemmin FAM76 PF16046.5 AFI82885.1 - 0.37 10.1 3.4 0.49 9.7 3.4 1.2 1 0 0 1 1 1 0 FAM76 protein bZIP_2 PF07716.15 AFI82885.1 - 0.46 10.6 13.8 6 7.0 0.4 3.5 1 1 2 3 3 3 0 Basic region leucine zipper ERM PF00769.19 AFI82885.1 - 0.46 10.3 15.8 4.3 7.1 15.5 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Csm1_N PF18504.1 AFI82885.1 - 0.49 10.8 12.8 1.5 9.2 2.0 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain CENP-H PF05837.12 AFI82885.1 - 0.5 10.8 11.1 0.78 10.2 11.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4239 PF14023.6 AFI82885.1 - 0.57 9.9 2.4 0.75 9.5 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Uso1_p115_C PF04871.13 AFI82885.1 - 0.61 10.5 12.7 2.1 8.7 12.1 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fzo_mitofusin PF04799.13 AFI82885.1 - 0.62 9.6 7.1 0.82 9.2 5.1 1.9 1 1 1 2 2 2 0 fzo-like conserved region Sec34 PF04136.15 AFI82885.1 - 0.64 9.9 8.0 1.7 8.5 7.9 1.7 1 1 0 1 1 1 0 Sec34-like family Phage_GP20 PF06810.11 AFI82885.1 - 0.74 9.6 9.2 2.5 7.9 9.3 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 CLZ PF16526.5 AFI82885.1 - 0.77 10.2 9.4 0.59 10.5 6.9 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlxA PF14282.6 AFI82885.1 - 0.84 9.7 15.7 0.42 10.6 5.2 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF724 PF05266.14 AFI82885.1 - 1 9.1 8.8 2 8.2 8.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FUSC PF04632.12 AFI82885.1 - 1.1 7.6 2.1 1.5 7.3 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nup54 PF13874.6 AFI82885.1 - 1.4 9.1 10.0 2.1 8.4 10.0 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.8 AFI82885.1 - 1.5 8.9 16.5 8.7 6.4 16.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.9 AFI82885.1 - 1.7 8.6 11.9 7.6 6.4 10.8 2.2 2 1 0 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.11 AFI82885.1 - 1.8 8.8 15.5 2.2 8.5 6.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 AFI82885.1 - 1.9 8.7 8.9 3.2 8.0 8.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APC_N_CC PF16689.5 AFI82885.1 - 1.9 8.6 9.1 4.6 7.4 3.7 2.6 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain TSC22 PF01166.18 AFI82885.1 - 2.1 8.7 9.9 3.5 8.0 1.1 3.0 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF1664 PF07889.12 AFI82885.1 - 2.3 8.3 5.4 7.2 6.7 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 AFI82885.1 - 2.4 8.7 8.9 4.2 7.9 0.8 2.6 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TolA_bind_tri PF16331.5 AFI82885.1 - 3.6 7.7 15.2 1.1 9.4 5.0 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF5320 PF17253.2 AFI82885.1 - 3.6 8.7 12.2 18 6.4 1.0 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5320) GrpE PF01025.19 AFI82885.1 - 4.4 6.9 13.0 92 2.6 13.0 2.1 1 1 0 1 1 1 0 GrpE YlqD PF11068.8 AFI82885.1 - 4.9 7.5 10.9 10 6.5 10.2 1.8 1 1 0 1 1 1 0 YlqD protein Fmp27_WPPW PF10359.9 AFI82885.1 - 4.9 5.9 10.8 11 4.7 10.8 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Swi5 PF07061.11 AFI82885.1 - 6 7.0 9.7 6e+02 0.6 9.7 2.6 1 1 0 1 1 1 0 Swi5 Cep57_CLD_2 PF14197.6 AFI82885.1 - 6.8 6.8 17.4 0.38 10.9 2.4 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2730 PF10805.8 AFI82885.1 - 9.8 6.3 8.9 27 4.9 4.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Putative_PNPOx PF01243.20 AFI82886.1 - 5.8e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 AFI82886.1 - 0.006 16.6 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Plk4_PB1 PF18190.1 AFI82886.1 - 0.023 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 Bile_Hydr_Trans PF04775.14 AFI82886.1 - 0.17 12.0 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region ABC_membrane PF00664.23 AFI82888.1 - 9.6e-34 117.3 13.5 1.2e-33 116.9 13.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AFI82888.1 - 2.6e-32 112.2 0.0 4.6e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AFI82888.1 - 4.1e-06 26.4 0.0 3.1e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AFI82888.1 - 7.3e-05 22.7 0.0 0.00044 20.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AFI82888.1 - 0.00021 21.0 0.1 0.0006 19.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI82888.1 - 0.00057 20.3 0.1 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AFI82888.1 - 0.0018 18.3 0.0 0.0056 16.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AFI82888.1 - 0.004 17.4 0.1 0.026 14.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain ABC_membrane_3 PF13748.6 AFI82888.1 - 0.0062 15.8 5.7 0.0062 15.8 5.7 2.4 2 1 0 2 2 2 1 ABC transporter transmembrane region IstB_IS21 PF01695.17 AFI82888.1 - 0.013 15.2 0.7 3.6 7.3 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 AFI82888.1 - 0.02 15.0 0.4 0.046 13.8 0.1 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_28 PF13521.6 AFI82888.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AFI82888.1 - 0.044 12.8 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 AFI82888.1 - 0.05 13.2 1.6 0.47 10.0 1.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AFI82888.1 - 0.067 13.2 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 AFI82888.1 - 0.082 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Dynamin family DUF815 PF05673.13 AFI82888.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 AFI82888.1 - 0.15 11.8 0.2 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase DUF4714 PF15833.5 AFI82888.1 - 0.16 11.9 1.0 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) AIG1 PF04548.16 AFI82888.1 - 0.17 11.2 1.5 3.4 6.9 0.1 2.4 2 0 0 2 2 2 0 AIG1 family Halogen_Hydrol PF10112.9 AFI82888.1 - 5.5 7.0 8.1 0.11 12.5 0.6 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ILVD_EDD PF00920.21 AFI82889.1 - 7.5e-222 737.5 2.5 8.5e-222 737.3 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_S27 PF01599.19 AFI82889.1 - 0.71 10.1 4.2 12 6.2 0.7 3.1 3 0 0 3 3 3 0 Ribosomal protein S27a AA_kinase PF00696.28 AFI82890.1 - 3.1e-17 63.0 0.3 6.1e-17 62.0 0.3 1.4 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_7 PF13508.7 AFI82890.1 - 1.4e-09 38.2 0.0 3.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AFI82890.1 - 8.1e-09 35.7 0.0 2.1e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AFI82890.1 - 6.4e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 AFI82891.1 - 1.1e-25 90.1 0.6 1.4e-25 89.8 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 AFI82891.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase HAD PF12710.7 AFI82892.1 - 4.2e-38 131.6 0.1 5.1e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AFI82892.1 - 0.0029 17.4 0.1 0.48 10.1 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase GatB_N PF02934.15 AFI82893.1 - 1.8e-114 381.7 0.0 2.5e-114 381.3 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AFI82893.1 - 6.9e-54 181.8 0.2 1.2e-53 181.0 0.2 1.4 1 0 0 1 1 1 1 GatB domain YqeY PF09424.10 AFI82893.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Yqey-like protein FIST PF08495.10 AFI82894.1 - 6.5e-37 127.2 0.0 1.1e-35 123.1 0.0 2.1 2 0 0 2 2 2 1 FIST N domain FIST_C PF10442.9 AFI82894.1 - 9.5e-31 106.5 0.0 1.2e-27 96.4 0.0 2.5 3 0 0 3 3 3 2 FIST C domain tRNA_bind PF01588.20 AFI82894.1 - 0.032 14.3 0.2 0.078 13.1 0.2 1.6 1 0 0 1 1 1 0 Putative tRNA binding domain GshA PF08886.11 AFI82895.1 - 9.5e-194 643.5 0.0 1.1e-193 643.4 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase ATPgrasp_YheCD PF14398.6 AFI82895.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp Response_reg PF00072.24 AFI82897.1 - 1.8e-27 95.7 0.0 2e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF5615 PF18480.1 AFI82897.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Response_reg PF00072.24 AFI82898.1 - 1.8e-25 89.3 0.2 2e-25 89.1 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain LUD_dom PF02589.15 AFI82898.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 LUD domain B12-binding PF02310.19 AFI82898.1 - 0.018 15.1 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain Redoxin PF08534.10 AFI82898.1 - 0.022 14.5 0.0 0.96 9.1 0.0 2.0 1 1 1 2 2 2 0 Redoxin Chaperone_III PF07824.12 AFI82898.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III secretion chaperone domain CheW PF01584.19 AFI82899.1 - 1.7e-21 76.3 0.0 2.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 CheW-like domain MCPsignal PF00015.21 AFI82900.1 - 5.1e-41 140.4 44.5 2.8e-40 138.0 26.5 2.5 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 AFI82900.1 - 0.0052 17.0 25.3 2.8 8.3 0.1 5.1 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF948) ALS2CR8 PF15299.6 AFI82900.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Reticulon PF02453.17 AFI82900.1 - 0.097 12.6 5.6 0.3 11.1 0.5 3.7 2 1 1 3 3 3 0 Reticulon T3SchapCesA PF11439.8 AFI82900.1 - 0.73 10.0 4.6 14 5.9 0.1 3.9 2 1 2 4 4 4 0 Type III secretion system filament chaperone CesA Fumble PF03630.14 AFI82900.1 - 1.6 7.8 8.5 0.67 9.1 0.6 2.3 2 0 0 2 2 2 0 Fumble HAMP PF00672.25 AFI82900.1 - 3.3 8.2 8.2 8.6 6.8 0.4 5.1 4 2 1 5 5 5 0 HAMP domain Syntaxin_2 PF14523.6 AFI82900.1 - 4.5 7.7 20.7 6 7.3 5.9 4.2 1 1 2 3 3 3 0 Syntaxin-like protein BLOC1_2 PF10046.9 AFI82900.1 - 4.7 7.6 20.4 0.35 11.2 1.5 4.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Suppressor_APC PF11414.8 AFI82900.1 - 6.6 6.9 9.2 8.9 6.5 0.1 3.9 3 1 1 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein Laminin_II PF06009.12 AFI82900.1 - 6.9 6.7 26.6 7.6 6.5 7.2 3.3 2 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 AFI82900.1 - 8.4 6.5 24.2 1.1 9.3 2.2 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF155 PF02582.14 AFI82900.1 - 9.8 6.2 11.4 2.6 8.1 4.9 2.8 2 1 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Hpt PF01627.23 AFI82901.1 - 1.1e-32 112.1 47.8 1.2e-15 57.6 0.1 9.0 8 1 1 9 9 9 4 Hpt domain Response_reg PF00072.24 AFI82901.1 - 3.4e-26 91.6 0.2 1.7e-25 89.4 0.2 2.4 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 AFI82901.1 - 6.8e-16 58.2 0.2 1.7e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AFI82901.1 - 1.4e-14 54.6 0.2 3.5e-14 53.3 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AFI82901.1 - 0.017 15.0 0.1 0.08 12.9 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF285 PF03382.14 AFI82901.1 - 0.038 13.7 0.2 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 CheW PF01584.19 AFI82902.1 - 1.5e-08 34.3 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 CheW-like domain SLT PF01464.20 AFI82903.1 - 3.5e-28 97.6 0.0 7.7e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_L PF14718.6 AFI82903.1 - 6.3e-13 48.7 1.9 6.3e-13 48.7 1.9 5.6 4 1 1 5 5 5 1 Soluble lytic murein transglycosylase L domain Cucumo_coat PF00760.18 AFI82903.1 - 0.00027 20.6 0.3 0.00067 19.4 0.3 1.6 1 0 0 1 1 1 1 Cucumovirus coat protein TPR_4 PF07721.14 AFI82903.1 - 0.087 13.5 6.9 0.23 12.2 1.5 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_lysozyme2 PF18013.1 AFI82903.1 - 0.13 12.3 3.4 0.17 11.9 0.0 2.7 2 1 1 3 3 3 0 Phage tail lysozyme TPR_6 PF13174.6 AFI82903.1 - 0.23 12.1 0.1 0.23 12.1 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 AFI82903.1 - 2.8 8.5 12.4 1.5 9.4 0.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat PolyA_pol PF01743.20 AFI82904.1 - 2.3e-19 70.1 0.0 5e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AFI82904.1 - 8e-14 51.2 0.2 1.5e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 AFI82904.1 - 2.9e-06 27.5 0.6 6.6e-06 26.4 0.6 1.6 1 0 0 1 1 1 1 HD domain MCH PF02289.16 AFI82905.1 - 1.6e-132 441.6 0.0 1.7e-132 441.4 0.0 1.0 1 0 0 1 1 1 1 Cyclohydrolase (MCH) tify PF06200.14 AFI82905.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 tify domain RimK PF08443.11 AFI82906.1 - 5.7e-26 91.3 0.0 7.4e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AFI82906.1 - 6.5e-08 32.9 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AFI82906.1 - 6.6e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AFI82906.1 - 1.2e-05 24.8 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AFI82906.1 - 1.5e-05 25.1 0.0 3.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AFI82906.1 - 0.00015 21.1 0.0 0.17 11.1 0.0 2.5 1 1 1 2 2 2 2 YheC/D like ATP-grasp R2K_3 PF14243.6 AFI82906.1 - 0.0052 16.8 0.2 0.017 15.1 0.2 1.8 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 3 CP_ATPgrasp_2 PF14403.6 AFI82906.1 - 0.012 14.5 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 R2K_2 PF18299.1 AFI82906.1 - 0.032 14.1 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 TTL PF03133.15 AFI82906.1 - 0.071 12.2 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family Dala_Dala_lig_C PF07478.13 AFI82906.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus CitG PF01874.16 AFI82907.1 - 2.4e-64 217.7 0.4 2.8e-64 217.5 0.4 1.0 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase Fae PF08714.11 AFI82908.1 - 5.5e-66 221.4 0.4 6.2e-66 221.2 0.4 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) His_biosynth PF00977.21 AFI82909.1 - 3.3e-25 88.9 0.0 3.8e-24 85.4 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein IGPS PF00218.21 AFI82909.1 - 0.025 13.7 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase CTK3_C PF12350.8 AFI82910.1 - 0.004 17.3 0.1 0.0052 16.9 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus preATP-grasp_3 PF18301.1 AFI82910.1 - 0.0057 16.9 0.0 0.0067 16.7 0.0 1.1 1 0 0 1 1 1 1 pre ATP-grasp 3 domain Phage_tail_APC PF16778.5 AFI82910.1 - 0.0085 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Phage tail assembly chaperone protein ATP-grasp_3 PF02655.14 AFI82911.1 - 6.9e-33 114.0 0.0 4.5e-32 111.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain preATP-grasp_3 PF18301.1 AFI82911.1 - 3.1e-08 33.8 0.0 9.5e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 pre ATP-grasp 3 domain RimK PF08443.11 AFI82911.1 - 1.1e-05 25.1 0.2 1.8e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 AFI82911.1 - 0.00042 19.7 0.1 0.041 13.1 0.1 2.2 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AFI82911.1 - 0.00063 19.5 0.0 0.0027 17.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 AFI82911.1 - 0.0084 15.7 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AFI82911.1 - 0.14 11.9 0.0 0.65 9.7 0.0 1.9 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ISET-FN3_linker PF16625.5 AFI82911.1 - 0.15 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO Hydantoinase_A PF01968.18 AFI82912.1 - 3.4e-11 43.0 0.0 1.5e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase Chorismate_bind PF00425.18 AFI82913.1 - 1.1e-97 326.7 0.0 1.4e-97 326.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AFI82913.1 - 1.2e-31 109.8 0.0 2.8e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region AA_kinase PF00696.28 AFI82914.1 - 8.7e-06 25.5 0.0 1.6e-05 24.6 0.0 1.5 1 1 1 2 2 2 1 Amino acid kinase family DUF3343 PF11823.8 AFI82914.1 - 0.00031 20.1 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3343) Pyridoxal_deC PF00282.19 AFI82915.1 - 2e-33 115.7 0.0 2.9e-32 111.8 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 AFI82915.1 - 1.7e-05 24.0 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AFI82915.1 - 0.018 14.2 0.4 0.1 11.7 0.0 2.1 3 0 0 3 3 3 0 Aminotransferase class I and II OKR_DC_1 PF01276.20 AFI82915.1 - 0.041 12.6 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 AFI82915.1 - 0.072 12.3 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase AAA_22 PF13401.6 AFI82916.1 - 3.4e-08 33.9 0.8 2.7e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AFI82916.1 - 2.4e-06 28.0 0.0 9.5e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SPOR PF05036.13 AFI82916.1 - 0.00052 20.3 0.3 0.043 14.2 0.0 3.1 4 0 0 4 4 3 1 Sporulation related domain ATPase_2 PF01637.18 AFI82916.1 - 0.0095 15.9 0.1 0.23 11.4 0.1 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AFI82916.1 - 0.021 15.2 6.5 0.08 13.3 2.8 2.9 2 1 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 AFI82916.1 - 0.026 13.7 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 AFI82916.1 - 0.036 13.2 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CmcI PF04989.12 AFI82916.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase AAA_7 PF12775.7 AFI82916.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 AFI82916.1 - 0.12 12.9 0.4 1.3 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain Topo-VIb_trans PF09239.11 AFI82916.1 - 0.13 12.1 0.1 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer AAA_30 PF13604.6 AFI82916.1 - 0.14 11.9 0.1 0.84 9.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF4045 PF13254.6 AFI82916.1 - 0.85 9.2 5.4 1.1 8.8 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) NACHT PF05729.12 AFI82916.1 - 1.5 8.7 9.7 1.9 8.4 6.1 2.6 2 1 0 2 2 2 0 NACHT domain DHQ_synthase PF01761.20 AFI82917.1 - 8.3e-111 369.3 0.0 9.9e-111 369.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AFI82917.1 - 6.2e-16 58.9 0.0 1.4e-15 57.7 0.0 1.5 1 1 1 2 2 2 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AFI82917.1 - 2.1e-09 36.7 0.5 5.1e-09 35.4 0.5 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Biotin_carb_N PF00289.22 AFI82917.1 - 0.016 15.8 0.0 0.95 10.0 0.0 2.5 2 0 0 2 2 2 0 Biotin carboxylase, N-terminal domain SKI PF01202.22 AFI82918.1 - 4e-54 183.0 1.1 4.5e-54 182.8 1.1 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AFI82918.1 - 9.3e-09 35.9 0.1 1.7e-08 35.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AFI82918.1 - 2e-06 28.0 0.3 2.8e-05 24.3 0.3 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.6 AFI82918.1 - 8.1e-06 26.1 0.2 1.7e-05 25.0 0.1 1.6 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 AFI82918.1 - 2.2e-05 24.3 1.9 0.00048 19.9 0.0 2.4 2 1 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 AFI82918.1 - 0.0024 18.3 0.4 0.013 16.0 0.4 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI82918.1 - 0.0029 18.0 2.0 0.14 12.5 2.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 AFI82918.1 - 0.0041 17.6 0.7 0.044 14.2 0.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AFI82918.1 - 0.011 15.7 0.2 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AFI82918.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 AFI82918.1 - 0.021 14.7 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase DRTGG PF07085.12 AFI82918.1 - 0.043 13.6 0.2 0.058 13.2 0.2 1.2 1 0 0 1 1 1 0 DRTGG domain AAA_22 PF13401.6 AFI82918.1 - 0.061 13.6 0.3 0.12 12.7 0.3 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AFI82918.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase BppL_N PF18338.1 AFI82918.1 - 0.17 11.7 5.2 0.13 12.1 1.9 2.1 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain MOZ_SAS PF01853.18 AFI82919.1 - 0.069 12.8 0.0 0.074 12.7 0.0 1.0 1 0 0 1 1 1 0 MOZ/SAS family Secretin PF00263.21 AFI82920.1 - 2.4e-47 160.7 2.4 2.4e-47 160.7 2.4 2.0 2 0 0 2 2 2 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AFI82920.1 - 1.4e-16 60.6 1.1 6.1e-16 58.6 0.1 2.7 3 0 0 3 3 3 1 Bacterial type II/III secretion system short domain AMIN PF11741.8 AFI82920.1 - 1.2e-11 44.6 4.6 2e-07 31.0 0.1 3.9 4 0 0 4 4 4 2 AMIN domain STN PF07660.14 AFI82920.1 - 2e-11 43.5 2.9 4.3e-10 39.2 0.0 3.6 4 0 0 4 4 4 1 Secretin and TonB N terminus short domain bPH_3 PF14470.6 AFI82920.1 - 0.029 14.7 0.0 0.26 11.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial PH domain PilP PF04351.13 AFI82921.1 - 1.7e-46 157.8 0.1 1.9e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Pilus assembly protein, PilP PagP PF07017.11 AFI82921.1 - 0.17 11.3 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP PilO PF04350.13 AFI82922.1 - 3.2e-53 179.8 0.3 3.9e-53 179.5 0.3 1.1 1 0 0 1 1 1 1 Pilus assembly protein, PilO HAUS5 PF14817.6 AFI82922.1 - 0.045 12.5 0.6 0.052 12.3 0.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DivIC PF04977.15 AFI82922.1 - 0.052 13.3 0.3 0.083 12.7 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator PilN PF05137.13 AFI82923.1 - 2.7e-16 59.4 0.2 6.6e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) Rab_bind PF16704.5 AFI82923.1 - 0.006 16.6 0.3 0.031 14.3 0.2 2.1 2 0 0 2 2 2 1 Rab binding domain DNA_ligase_A_M PF01068.21 AFI82923.1 - 0.012 15.2 0.5 0.016 14.9 0.5 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Pertactin PF03212.14 AFI82923.1 - 0.04 13.9 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Pertactin DUF2304 PF10066.9 AFI82923.1 - 0.085 13.1 0.4 0.14 12.4 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) AI-2E_transport PF01594.16 AFI82923.1 - 0.14 11.3 0.7 0.2 10.7 0.7 1.1 1 0 0 1 1 1 0 AI-2E family transporter PilM_2 PF11104.8 AFI82924.1 - 5.7e-135 449.7 0.3 6.4e-135 449.6 0.3 1.0 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.6 AFI82924.1 - 4e-09 36.8 0.1 1.1e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 AFI82924.1 - 1.6e-05 23.9 0.4 0.053 12.3 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Transgly PF00912.22 AFI82925.1 - 1.6e-61 206.8 0.0 2.6e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AFI82925.1 - 5e-27 94.9 0.0 2e-24 86.4 0.0 2.9 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain PCB_OB PF17092.5 AFI82925.1 - 8.5e-25 87.7 0.0 1.7e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain MCPsignal PF00015.21 AFI82926.1 - 5.1e-33 114.3 8.4 1.1e-32 113.2 8.4 1.6 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain CZB PF13682.6 AFI82926.1 - 7.8e-13 48.7 0.0 2.2e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain DUF1664 PF07889.12 AFI82926.1 - 0.048 13.7 5.6 4.3 7.4 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 AFI82926.1 - 0.17 11.9 6.7 4 7.5 0.3 3.0 2 1 1 3 3 3 0 Laminin Domain II WRNPLPNID PF15017.6 AFI82926.1 - 0.32 11.9 2.8 0.42 11.5 0.3 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF948 PF06103.11 AFI82926.1 - 0.37 11.1 5.8 5 7.4 0.5 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AFI82926.1 - 0.54 10.4 7.6 3.1 8.0 0.0 3.4 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.11 AFI82926.1 - 0.77 10.0 4.4 11 6.3 0.6 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF1319) CENP-H PF05837.12 AFI82926.1 - 7.8 7.0 21.1 7.7 7.0 2.0 4.2 4 0 0 4 4 4 0 Centromere protein H (CENP-H) NnrS PF05940.12 AFI82927.1 - 1.3e-46 159.7 48.9 1.8e-46 159.2 48.9 1.1 1 0 0 1 1 1 1 NnrS protein DUF2723 PF11028.8 AFI82927.1 - 0.039 13.9 6.6 0.17 11.8 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2723) Rrf2 PF02082.20 AFI82928.1 - 4.2e-23 81.5 0.0 6.3e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 AFI82928.1 - 2.3e-07 30.6 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AFI82928.1 - 0.00022 21.6 0.0 0.00046 20.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AFI82928.1 - 0.00079 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AFI82928.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AFI82928.1 - 0.0013 18.3 0.0 0.007 15.9 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 AFI82928.1 - 0.0017 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_34 PF13601.6 AFI82928.1 - 0.014 15.6 0.0 0.038 14.2 0.0 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_10 PF04967.12 AFI82928.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_36 PF13730.6 AFI82928.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AFI82928.1 - 0.044 13.8 0.1 0.091 12.8 0.0 1.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AFI82928.1 - 0.045 13.7 0.1 0.074 13.0 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 AFI82928.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SgrR_N PF12793.7 AFI82928.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term PuR_N PF09182.10 AFI82928.1 - 0.078 12.9 0.1 0.29 11.1 0.1 1.9 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal YjcQ PF09639.10 AFI82928.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 YjcQ protein SpoIIID PF12116.8 AFI82928.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_23 PF13384.6 AFI82928.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Hemerythrin PF01814.23 AFI82929.1 - 1.2e-24 87.4 5.1 1.2e-24 87.4 5.1 1.7 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain ScdA_N PF04405.14 AFI82929.1 - 3.8e-21 74.5 0.1 6.4e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) NUC202 PF08166.12 AFI82929.1 - 0.068 13.3 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 NUC202 domain Peptidase_M48 PF01435.18 AFI82931.1 - 9.3e-36 123.4 0.1 1.3e-35 122.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Ribosomal_L31 PF01197.18 AFI82932.1 - 1.7e-33 114.6 0.1 1.9e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 zf-TFIIB PF13453.6 AFI82932.1 - 0.063 12.6 1.8 0.1 11.9 1.8 1.3 1 0 0 1 1 1 0 Transcription factor zinc-finger TehB PF03848.14 AFI82933.1 - 2.2e-10 40.2 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 AFI82933.1 - 1e-09 38.9 0.0 1.5e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI82933.1 - 6.2e-09 35.9 0.0 8.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI82933.1 - 2.7e-07 31.2 0.0 4.3e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI82933.1 - 5.5e-07 29.5 0.0 7.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AFI82933.1 - 6.1e-07 29.1 0.1 9.5e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 AFI82933.1 - 4.7e-05 24.1 0.0 6.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AFI82933.1 - 9.6e-05 22.1 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 AFI82933.1 - 0.00013 21.7 0.0 0.00067 19.4 0.0 1.8 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 AFI82933.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 AFI82933.1 - 0.033 13.8 0.1 4.2 6.9 0.0 2.1 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_15 PF09445.10 AFI82933.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FmrO PF07091.11 AFI82933.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TrkH PF02386.16 AFI82934.1 - 1.9e-86 290.6 19.5 6.6e-86 288.7 19.5 1.7 1 1 0 1 1 1 1 Cation transport protein DUF3290 PF11694.8 AFI82934.1 - 1.2 9.1 4.0 21 5.1 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) CN_hydrolase PF00795.22 AFI82935.1 - 1e-27 97.2 0.0 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CorC_HlyC PF03471.17 AFI82936.1 - 6e-21 74.3 0.1 1.4e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AFI82936.1 - 1.3e-15 57.6 5.0 5.6e-09 36.3 0.9 2.9 3 0 0 3 3 3 2 CBS domain UPF0054 PF02130.17 AFI82937.1 - 2.4e-38 130.8 0.0 2.8e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PhoH PF02562.16 AFI82938.1 - 3.1e-91 304.4 0.0 4.1e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AFI82938.1 - 1.3e-10 41.4 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AFI82938.1 - 1.7e-05 25.2 0.0 5e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AFI82938.1 - 0.00038 20.2 0.0 0.00097 18.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AFI82938.1 - 0.0026 18.1 0.0 0.0095 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Fumerase PF05681.14 AFI82938.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Zot PF05707.12 AFI82938.1 - 0.065 12.9 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_25 PF13481.6 AFI82938.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain BSP PF04450.12 AFI82938.1 - 0.085 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria AAA PF00004.29 AFI82938.1 - 0.088 13.2 0.1 0.2 12.1 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI82938.1 - 0.09 13.2 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 AFI82938.1 - 0.097 12.4 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Radical_SAM PF04055.21 AFI82939.1 - 3.9e-29 102.2 0.1 6.1e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AFI82939.1 - 5.1e-29 100.2 0.0 1.3e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AFI82939.1 - 8e-20 70.6 0.1 1.3e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 AFI82939.1 - 0.0026 17.9 0.1 0.012 15.7 0.1 2.1 1 1 0 1 1 1 1 TRAM domain CodY PF06018.14 AFI82939.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Haem_degrading PF03928.14 AFI82942.1 - 5.8e-31 107.0 0.2 6.5e-31 106.9 0.2 1.0 1 0 0 1 1 1 1 Haem-degrading TSP_C PF05735.12 AFI82943.1 - 7.4e-36 123.9 4.0 1.1e-35 123.3 4.0 1.2 1 0 0 1 1 1 1 Thrombospondin C-terminal region YcaO PF02624.16 AFI82944.1 - 5.2e-78 262.6 0.0 9.6e-78 261.7 0.0 1.5 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding YcaO_C PF18381.1 AFI82944.1 - 5.2e-56 189.2 0.1 7.8e-56 188.7 0.1 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase C-terminal domain Na_H_Exchanger PF00999.21 AFI82945.1 - 4e-38 131.2 49.0 1.2e-37 129.6 49.0 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AFI82945.1 - 2e-18 66.7 0.0 3.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 AFI82945.1 - 5.9e-05 22.5 0.0 9.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 AFI82945.1 - 0.0049 16.4 0.0 0.0082 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 AFI82945.1 - 0.023 14.3 0.2 0.035 13.7 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 AFI82945.1 - 0.079 13.8 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AFI82945.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 AFI82945.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF1840 PF08895.11 AFI82946.1 - 2.9e-30 104.8 0.1 1.1e-29 103.0 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1840) ETC_C1_NDUFA4 PF04800.12 AFI82948.1 - 0.045 14.0 0.0 0.061 13.6 0.0 1.1 1 0 0 1 1 1 0 ETC complex I subunit conserved region DUF1971 PF09313.11 AFI82949.1 - 2.6e-24 85.0 0.0 3e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1971) UDG PF03167.19 AFI82950.1 - 9.7e-28 97.1 0.0 1.1e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4918 PF16265.5 AFI82950.1 - 0.067 12.7 0.0 0.9 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4918) DUF1488 PF07369.11 AFI82951.1 - 6.6e-10 38.8 0.0 7e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1488) DUF4010 PF13194.6 AFI82952.1 - 1.3e-66 224.3 16.9 1.3e-66 224.3 16.9 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4010) MgtC PF02308.16 AFI82952.1 - 6.1e-20 71.8 9.1 6.1e-20 71.8 9.1 3.4 2 1 1 3 3 3 1 MgtC family DUF5360 PF17314.2 AFI82952.1 - 0.059 13.4 0.1 0.059 13.4 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5360) DUF1664 PF07889.12 AFI82952.1 - 7.7 6.6 5.6 19 5.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PLDc_2 PF13091.6 AFI82953.1 - 1.5e-27 96.1 0.0 6.9e-23 81.0 0.0 3.0 2 1 1 3 3 3 2 PLD-like domain PP_kinase_C PF13090.6 AFI82953.1 - 0.034 13.6 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 2 PP_kinase_C_1 PF17941.1 AFI82953.1 - 0.038 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 Metallophos PF00149.28 AFI82954.1 - 3.2e-13 50.7 0.0 1.5e-12 48.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 AFI82954.1 - 0.00069 20.1 0.1 0.0016 19.0 0.1 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 AFI82954.1 - 0.0068 16.6 0.0 0.34 11.1 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PBP_like_2 PF12849.7 AFI82955.1 - 4.6e-51 174.1 0.7 5.7e-51 173.8 0.7 1.0 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 AFI82955.1 - 6.4e-13 49.3 0.3 1.4e-12 48.2 0.3 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AFI82955.1 - 4.9e-10 38.9 0.0 7.9e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain Virul_fac_BrkB PF03631.15 AFI82956.1 - 7.6e-60 202.7 26.2 8.7e-60 202.5 26.2 1.0 1 0 0 1 1 1 1 Virulence factor BrkB DUF3290 PF11694.8 AFI82956.1 - 0.93 9.5 4.3 0.22 11.5 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4179 PF13786.6 AFI82956.1 - 1.2 9.6 3.5 2.5 8.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Ldh_1_N PF00056.23 AFI82958.1 - 1.7e-32 112.5 0.1 2.5e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AFI82958.1 - 1.1e-28 100.3 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 AFI82958.1 - 0.00083 19.0 0.2 0.02 14.5 0.2 2.4 1 1 0 1 1 1 1 Family 4 glycosyl hydrolase ALF PF03752.13 AFI82960.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Short repeats of unknown function PsiE PF06146.12 AFI82961.1 - 3.2e-19 69.1 6.2 3.2e-19 69.1 6.2 1.6 2 0 0 2 2 2 1 Phosphate-starvation-inducible E PROCT PF08084.11 AFI82961.1 - 0.091 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 PROCT (NUC072) domain MOSC PF03473.17 AFI82962.1 - 2.1e-26 92.5 0.0 3.1e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 AFI82962.1 - 1.8e-10 40.5 3.1 3e-10 39.8 3.1 1.4 1 0 0 1 1 1 1 3-alpha domain p450 PF00067.22 AFI82964.1 - 1.4e-26 93.3 0.0 3.5e-22 78.8 0.0 3.1 1 1 0 1 1 1 1 Cytochrome P450 NusB PF01029.18 AFI82964.1 - 0.037 14.2 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 NusB family LtuB PF17455.2 AFI82964.1 - 0.1 13.2 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Late transcription unit B RadC PF04002.15 AFI82965.1 - 2.2e-44 150.3 0.0 3.2e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AFI82965.1 - 0.00022 21.0 0.1 0.00034 20.4 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TrkA_TMD PF18613.1 AFI82965.1 - 0.36 10.3 1.5 0.81 9.2 1.5 1.5 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain PepSY_TM PF03929.16 AFI82966.1 - 4e-59 200.6 5.2 4.8e-59 200.4 5.2 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AFI82966.1 - 9.2e-08 32.5 0.0 6.6e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain Ni_hydr_CYTB PF01292.20 AFI82967.1 - 1.4e-32 112.8 9.9 1.6e-32 112.6 9.9 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AFI82967.1 - 0.0015 19.0 23.3 0.33 11.5 10.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4405) Cytochrom_B561 PF03188.16 AFI82967.1 - 0.047 13.8 1.2 0.047 13.8 1.2 2.4 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 PepSY_TM PF03929.16 AFI82967.1 - 3.1 7.4 7.3 8.9 5.9 7.3 1.9 1 1 0 1 1 1 0 PepSY-associated TM region Hemerythrin PF01814.23 AFI82968.1 - 0.00015 22.4 0.2 0.00053 20.6 0.2 1.7 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4119 PF13494.6 AFI82968.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Usg PF06233.12 AFI82968.1 - 0.05 13.7 0.7 0.15 12.3 0.0 2.1 2 1 0 2 2 2 0 Usg-like family Integrase_1 PF12835.7 AFI82968.1 - 0.077 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Integrase Thymidylat_synt PF00303.19 AFI82969.1 - 2.7e-110 367.7 0.0 3.4e-110 367.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DUF1205 PF06722.12 AFI82969.1 - 0.12 12.5 0.1 2 8.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1205) Sigma54_activat PF00158.26 AFI82970.1 - 4.4e-44 150.2 0.1 1e-43 149.0 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AFI82970.1 - 4.6e-17 62.4 0.2 1.1e-16 61.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AFI82970.1 - 8.8e-15 54.2 1.3 8.8e-15 54.2 1.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI82970.1 - 8.8e-08 32.2 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AFI82970.1 - 0.00027 21.1 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AFI82970.1 - 0.00067 19.1 0.3 0.024 14.0 0.1 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_30 PF13556.6 AFI82970.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 AFI82970.1 - 0.0022 17.5 0.1 0.0067 16.0 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain MCM PF00493.23 AFI82970.1 - 0.0043 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_7 PF12775.7 AFI82970.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 AFI82970.1 - 0.013 15.8 0.0 0.16 12.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 AFI82970.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF900 PF05990.12 AFI82970.1 - 0.068 12.7 0.1 0.097 12.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) AAA_18 PF13238.6 AFI82970.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AFI82970.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DsbD_2 PF13386.6 AFI82971.1 - 1.1e-50 172.4 21.5 1.3e-50 172.2 21.5 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD PF02683.15 AFI82971.1 - 0.00019 21.4 18.1 0.0017 18.3 17.5 1.9 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region COX7C PF02935.16 AFI82971.1 - 0.16 12.3 0.3 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Cytochrome_CBB3 PF13442.6 AFI82972.1 - 2.4e-12 47.0 0.1 3.4e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AFI82972.1 - 0.00011 23.3 0.5 0.00044 21.3 0.5 1.9 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 AFI82972.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 1 0 1 1 1 0 Cytochrome c-550 domain Ppx-GppA PF02541.16 AFI82974.1 - 2.7e-78 263.3 0.8 4.2e-78 262.7 0.8 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family HD PF01966.22 AFI82974.1 - 0.005 17.0 0.6 0.014 15.6 0.6 1.7 1 0 0 1 1 1 1 HD domain BsuBI_PstI_RE_N PF17728.1 AFI82974.1 - 0.093 12.6 0.1 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease HTH domain FtsA PF14450.6 AFI82974.1 - 0.17 12.3 0.0 30 5.1 0.0 3.3 3 0 0 3 3 3 0 Cell division protein FtsA PhoU PF01895.19 AFI82975.1 - 2.5e-42 143.2 4.8 1.5e-23 83.1 0.3 2.2 2 0 0 2 2 2 2 PhoU domain ABC_tran PF00005.27 AFI82976.1 - 1.8e-30 106.3 0.0 2.6e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI82976.1 - 2.2e-10 40.9 0.3 0.00022 21.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI82976.1 - 4.4e-07 29.6 0.2 3.5e-05 23.3 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AFI82976.1 - 4.1e-06 27.4 0.1 8.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AFI82976.1 - 6.6e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AFI82976.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFI82976.1 - 0.00074 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AFI82976.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AFI82976.1 - 0.005 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AFI82976.1 - 0.0088 16.4 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AFI82976.1 - 0.034 13.7 0.0 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 AFI82976.1 - 0.07 12.5 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 AFI82976.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AFI82976.1 - 0.094 12.4 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 AFI82977.1 - 2.4e-14 53.5 17.0 2.4e-14 53.5 17.0 2.6 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component PNPase PF03726.14 AFI82977.1 - 0.16 12.5 2.1 0.3 11.6 2.1 1.4 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain BPD_transp_1 PF00528.22 AFI82978.1 - 1.7e-13 50.7 32.2 2.8e-12 46.8 27.5 3.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Utp8 PF10395.9 AFI82978.1 - 0.13 10.8 0.0 0.28 9.6 0.0 1.4 2 0 0 2 2 2 0 Utp8 family Sigma_reg_N PF13800.6 AFI82978.1 - 0.86 9.9 3.6 67 3.9 0.2 3.6 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PBP_like_2 PF12849.7 AFI82979.1 - 4.7e-33 115.1 0.6 8.4e-33 114.2 0.6 1.3 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AFI82979.1 - 3e-11 42.8 0.0 4.2e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AFI82979.1 - 1.9e-07 31.1 0.0 3.3e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AFI82979.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain PhoR PF11808.8 AFI82980.1 - 2.2e-21 76.0 2.1 3.5e-21 75.4 0.9 2.0 2 0 0 2 2 2 1 Phosphate regulon sensor protein PhoR HATPase_c PF02518.26 AFI82980.1 - 2.2e-20 73.2 0.0 3.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI82980.1 - 5e-19 68.1 1.7 1.4e-18 66.7 0.5 2.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AFI82980.1 - 0.00074 19.5 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4446 PF14584.6 AFI82980.1 - 0.017 15.1 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HATPase_c_5 PF14501.6 AFI82980.1 - 0.02 14.8 0.0 0.093 12.6 0.0 2.1 2 0 0 2 2 2 0 GHKL domain PAS PF00989.25 AFI82980.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 AFI82980.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain ApoLp-III PF07464.11 AFI82980.1 - 0.069 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) HATPase_c_3 PF13589.6 AFI82980.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FixQ PF05545.11 AFI82980.1 - 0.45 10.5 2.5 0.88 9.6 2.5 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Response_reg PF00072.24 AFI82981.1 - 3.5e-32 110.9 0.0 5.7e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI82981.1 - 1.9e-26 91.9 0.1 3.5e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AFI82981.1 - 0.078 13.3 0.0 0.23 11.9 0.0 1.9 2 1 0 2 2 2 0 Flagellar regulatory protein FleQ MFS_1 PF07690.16 AFI82982.1 - 5.5e-16 58.4 59.4 3.4e-15 55.9 28.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.20 AFI82983.1 - 6.2e-109 364.1 21.8 9.4e-109 363.5 21.8 1.3 1 0 0 1 1 1 1 Phosphate transporter family TMPIT PF07851.13 AFI82983.1 - 0.006 15.9 4.3 0.011 15.1 4.3 1.3 1 0 0 1 1 1 1 TMPIT-like protein FapA PF03961.13 AFI82983.1 - 0.0092 14.6 1.7 0.014 14.0 1.7 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A MscS_porin PF12795.7 AFI82983.1 - 0.047 13.2 4.3 0.066 12.8 4.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain EzrA PF06160.12 AFI82983.1 - 0.05 11.8 7.1 0.072 11.3 7.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 AFI82983.1 - 0.35 9.5 5.5 0.48 9.0 5.5 1.1 1 0 0 1 1 1 0 AAA domain DUF1043 PF06295.12 AFI82983.1 - 0.62 10.1 2.7 4.5 7.3 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) APG6_N PF17675.1 AFI82983.1 - 1.2 9.7 8.1 2.2 8.8 8.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 AFI82983.1 - 5.5 7.5 12.7 0.038 14.4 4.1 1.8 3 0 0 3 3 3 0 Cell division protein ZapB DsbC PF11412.8 AFI82984.1 - 1.7e-27 95.9 0.0 2.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC DsbD PF02683.15 AFI82984.1 - 7.1e-18 65.3 17.7 1.2e-17 64.5 17.7 1.4 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin PF00085.20 AFI82984.1 - 9.2e-13 48.1 0.0 1.4e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AFI82984.1 - 2.6e-10 40.7 0.0 5.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AFI82984.1 - 3.2e-10 40.0 0.1 5.7e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like DsbD_2 PF13386.6 AFI82984.1 - 1.4e-08 34.9 24.7 1.4e-08 34.9 24.7 2.5 1 1 2 3 3 3 1 Cytochrome C biogenesis protein transmembrane region Thioredox_DsbH PF03190.15 AFI82984.1 - 0.00041 20.4 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 DHquinase_II PF01220.19 AFI82985.1 - 1.4e-60 202.9 0.1 1.6e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II MoaE PF02391.17 AFI82985.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 MoaE protein Biotin_lipoyl PF00364.22 AFI82986.1 - 5.8e-24 83.7 0.7 1.2e-23 82.7 0.2 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AFI82986.1 - 8.8e-08 31.9 0.3 0.014 15.3 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 AFI82986.1 - 0.0029 17.5 0.2 0.0042 17.0 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 AFI82986.1 - 0.046 13.6 0.1 0.16 11.9 0.1 1.8 1 1 1 2 2 2 0 Glycine cleavage H-protein CPSase_L_D2 PF02786.17 AFI82987.1 - 2.4e-81 272.3 0.0 3.4e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AFI82987.1 - 6.3e-43 145.8 0.0 1.6e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AFI82987.1 - 4.2e-38 129.8 0.0 8.5e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AFI82987.1 - 1.4e-08 34.5 0.0 3.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AFI82987.1 - 8.3e-07 29.2 0.0 2.3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 AFI82987.1 - 0.028 14.6 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 PrmA PF06325.13 AFI82988.1 - 1.2e-92 310.5 0.0 1.3e-92 310.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AFI82988.1 - 9.2e-10 38.3 0.0 1.4e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AFI82988.1 - 7.3e-09 35.6 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI82988.1 - 1.7e-07 31.9 0.0 3.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI82988.1 - 8.1e-06 25.8 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI82988.1 - 5.1e-05 23.8 0.1 0.00013 22.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AFI82988.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AFI82988.1 - 0.00031 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 AFI82988.1 - 0.0011 18.7 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 AFI82988.1 - 0.0023 17.7 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_9 PF08003.11 AFI82988.1 - 0.0088 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 AFI82988.1 - 0.0091 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase N6_N4_Mtase PF01555.18 AFI82988.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 DNA methylase UPF0020 PF01170.18 AFI82988.1 - 0.014 15.1 1.1 0.089 12.5 1.0 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 AFI82988.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 AFI82988.1 - 0.046 13.2 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 AFI82988.1 - 0.054 14.2 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AFI82988.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 AFI82988.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Dus PF01207.17 AFI82989.1 - 3.8e-110 367.8 0.4 4.5e-110 367.6 0.4 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AFI82989.1 - 7.1e-06 25.4 0.1 0.075 12.2 0.0 2.4 1 1 2 3 3 3 2 Dihydroorotate dehydrogenase Pterin_bind PF00809.22 AFI82989.1 - 0.0048 16.6 0.1 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 Pterin binding enzyme NanE PF04131.14 AFI82989.1 - 0.0069 15.6 0.3 0.019 14.1 0.1 1.8 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.17 AFI82989.1 - 0.0082 15.9 2.7 0.096 12.5 0.5 2.5 1 1 2 3 3 3 1 SOR/SNZ family ThiG PF05690.14 AFI82989.1 - 0.19 11.0 3.8 0.15 11.4 0.3 2.2 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG HTH_8 PF02954.19 AFI82990.1 - 9.5e-17 60.5 0.2 1.4e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Phage_NinH PF06322.11 AFI82990.1 - 0.00058 19.7 0.1 0.0025 17.6 0.1 1.9 1 1 1 2 2 2 1 Phage NinH protein HTH_30 PF13556.6 AFI82990.1 - 0.0012 18.6 0.1 0.0028 17.4 0.1 1.6 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AFI82990.1 - 0.0039 17.3 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.13 AFI82990.1 - 0.057 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_psq PF05225.16 AFI82990.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_23 PF13384.6 AFI82990.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain AICARFT_IMPCHas PF01808.18 AFI82991.1 - 1.8e-117 392.0 4.7 2.2e-117 391.7 4.7 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 AFI82991.1 - 3.1e-30 104.2 0.0 1e-29 102.5 0.0 2.0 2 0 0 2 2 2 1 MGS-like domain Adenylate_cycl PF01295.18 AFI82992.1 - 2.2e-46 158.7 16.6 3e-46 158.3 16.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase, class-I Adenyl_cycl_N PF12633.7 AFI82992.1 - 2e-33 116.0 0.0 1.8e-32 112.9 0.0 2.5 1 1 0 1 1 1 1 Adenylate cyclase NT domain Semialdhyde_dh PF01118.24 AFI82993.1 - 1.8e-37 128.4 0.0 3.1e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AFI82993.1 - 8e-19 68.4 0.0 1.2e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 AFI82993.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 AFI82993.1 - 0.072 13.7 0.0 0.25 12.0 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4917 PF16263.5 AFI82995.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4917) SlyX PF04102.12 AFI82995.1 - 3.5 8.3 13.1 7.4 7.3 13.1 1.6 1 0 0 1 1 1 0 SlyX Bactofilin PF04519.13 AFI82996.1 - 3.3e-24 85.0 0.8 4e-24 84.8 0.8 1.1 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Fe-S_biosyn PF01521.20 AFI82997.1 - 6.9e-19 68.1 0.0 7.9e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2254 PF10011.9 AFI82998.1 - 2.8e-104 348.9 3.9 3.4e-104 348.6 3.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) NS3_envE PF02723.14 AFI82998.1 - 0.1 12.7 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E TetR_N PF00440.23 AFI82999.1 - 3.3e-13 49.2 0.1 5e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_10 PF16295.5 AFI82999.1 - 9.7e-07 29.1 0.1 2.9e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 AFI82999.1 - 0.0002 21.5 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_3 PF01381.22 AFI82999.1 - 0.078 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_40 PF14493.6 AFI82999.1 - 0.1 13.1 0.0 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AFI82999.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase MerR_1 PF13411.6 AFI82999.1 - 0.14 12.2 0.0 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein HlyD_D23 PF16576.5 AFI83000.1 - 2.3e-14 53.2 2.7 7.3e-14 51.5 2.7 1.8 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI83000.1 - 7.8e-12 45.8 1.2 9.9e-09 35.9 0.1 3.0 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI83000.1 - 9.4e-11 41.4 6.9 8.1e-09 35.2 0.3 3.4 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD PF00529.20 AFI83000.1 - 1.5e-05 24.7 0.3 1.5e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS DUF3324 PF11797.8 AFI83000.1 - 0.065 13.2 0.1 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) OEP PF02321.18 AFI83000.1 - 0.37 10.6 16.4 0.13 12.1 12.1 2.3 3 1 0 3 3 3 0 Outer membrane efflux protein ACR_tran PF00873.19 AFI83001.1 - 0 1272.6 16.2 0 1272.4 16.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI83001.1 - 2.2e-10 40.0 8.7 2.2e-10 40.0 8.7 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AFI83001.1 - 0.067 12.6 35.7 0.0081 15.6 14.7 3.1 4 0 0 4 4 4 0 Protein export membrane protein OEP PF02321.18 AFI83002.1 - 1.1e-52 178.7 31.6 2.7e-26 92.5 15.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein 2OG-Fe_Oxy_2 PF10014.9 AFI83002.1 - 0.028 14.2 0.5 0.22 11.3 0.1 2.3 2 0 0 2 2 2 0 2OG-Fe dioxygenase Cadherin_2 PF08266.12 AFI83002.1 - 0.071 13.0 0.4 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Cadherin-like PLDc_N PF13396.6 AFI83003.1 - 7e-09 35.5 17.8 1.4e-08 34.5 17.6 1.6 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal BCCT PF02028.17 AFI83004.1 - 1.8e-186 620.4 50.0 2.1e-186 620.1 50.0 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter DUF4235 PF14019.6 AFI83004.1 - 0.056 13.5 0.3 0.26 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) LysR_substrate PF03466.20 AFI83006.1 - 7.6e-21 74.4 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AFI83006.1 - 3.3e-15 55.8 1.3 5.6e-15 55.0 0.7 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AFI83006.1 - 0.0053 16.5 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AFI83006.1 - 0.056 13.0 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AFI83006.1 - 0.074 13.1 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain GGDEF PF00990.21 AFI83007.1 - 2.8e-50 170.2 0.0 5.3e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AFI83007.1 - 1.6e-34 118.1 1.0 1.9e-16 60.1 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AFI83007.1 - 6.8e-20 71.4 0.0 1.1e-12 48.2 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AFI83007.1 - 7.7e-19 67.8 0.0 5.8e-13 48.8 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AFI83007.1 - 1.1e-17 64.2 0.0 1e-09 38.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 AFI83007.1 - 5.7e-09 36.1 0.1 3e-05 24.1 0.0 3.1 3 1 0 3 3 3 2 PAS domain PAS_8 PF13188.7 AFI83007.1 - 0.0017 18.3 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 PAS domain Glyoxalase PF00903.25 AFI83008.1 - 2e-20 73.3 0.1 2.6e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AFI83008.1 - 8.7e-15 54.9 0.0 6e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AFI83008.1 - 4.5e-05 24.2 0.0 0.00013 22.7 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AFI83008.1 - 0.00088 19.2 0.0 0.084 12.8 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase-like domain CorA PF01544.18 AFI83009.1 - 1.5e-57 195.2 0.5 1.7e-57 195.0 0.5 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 AFI83009.1 - 0.082 13.0 5.7 1.5 8.9 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_12 PF08242.12 AFI83010.1 - 6.4e-11 42.9 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83010.1 - 1.5e-09 38.4 0.0 2.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83010.1 - 3.9e-08 33.3 0.0 5.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83010.1 - 4.9e-07 29.7 0.0 6.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AFI83010.1 - 1.4e-05 24.2 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 AFI83010.1 - 3.1e-05 23.5 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 AFI83010.1 - 6.9e-05 22.3 0.0 8.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 AFI83010.1 - 0.00018 22.1 0.0 0.00025 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AFI83010.1 - 0.00051 19.7 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AFI83010.1 - 0.0048 16.5 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 AFI83010.1 - 0.0048 16.8 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AFI83010.1 - 0.0058 16.6 0.0 0.0074 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AFI83010.1 - 0.025 13.9 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_5 PF01795.19 AFI83010.1 - 0.045 13.2 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family AAA_9 PF12781.7 AFI83010.1 - 0.089 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region NodS PF05401.11 AFI83010.1 - 0.092 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MnmE_helical PF12631.7 AFI83011.1 - 1.4e-56 191.9 4.2 1.9e-56 191.5 4.2 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 AFI83011.1 - 1.6e-38 131.6 0.6 1e-37 129.0 0.1 2.5 3 0 0 3 3 3 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 AFI83011.1 - 2.6e-20 72.6 0.0 5.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI83011.1 - 1.3e-07 31.3 0.0 3.6e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AFI83011.1 - 0.00045 20.2 0.1 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 AFI83011.1 - 0.0023 17.3 0.1 0.006 15.9 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 AFI83011.1 - 0.0038 17.3 0.1 0.033 14.3 0.0 2.3 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.6 AFI83011.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AFI83011.1 - 0.054 12.8 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF4350 PF14258.6 AFI83011.1 - 0.069 13.6 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Gtr1_RagA PF04670.12 AFI83011.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region YidC_periplas PF14849.6 AFI83012.1 - 5.4e-80 269.3 0.2 7e-80 268.9 0.2 1.1 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 AFI83012.1 - 2.9e-61 206.2 8.0 4.1e-61 205.7 8.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Ribonuclease_P PF00825.18 AFI83013.1 - 1.2e-26 93.0 0.0 1.3e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P Complex1_LYR PF05347.15 AFI83013.1 - 0.057 13.5 0.9 0.1 12.7 0.7 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Ribosomal_L34 PF00468.17 AFI83014.1 - 1.7e-24 85.5 10.0 1.8e-24 85.4 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Bac_DnaA PF00308.18 AFI83015.1 - 1.2e-92 309.8 0.1 2.8e-92 308.5 0.1 1.7 2 0 0 2 2 2 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AFI83015.1 - 3.3e-32 110.3 0.2 1.1e-31 108.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 AFI83015.1 - 1.3e-12 47.3 0.0 2.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 AFI83015.1 - 1e-09 38.4 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 AFI83015.1 - 8.4e-07 29.5 0.0 3.3e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI83015.1 - 0.0002 21.8 0.5 0.00057 20.3 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 AFI83015.1 - 0.0015 18.5 0.1 0.0039 17.1 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AFI83015.1 - 0.006 16.9 1.9 0.31 11.3 0.5 3.0 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 AFI83015.1 - 0.0064 16.5 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain Kinesin PF00225.23 AFI83015.1 - 0.0086 15.0 0.0 0.013 14.5 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain ResIII PF04851.15 AFI83015.1 - 0.01 15.8 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AFI83015.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 1 0 NACHT domain Microtub_bd PF16796.5 AFI83015.1 - 0.034 14.1 0.0 0.16 11.9 0.0 2.2 2 2 0 2 2 2 0 Microtubule binding RNA_helicase PF00910.22 AFI83015.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 AFI83015.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_beta_2 PF02767.16 AFI83016.1 - 1.2e-42 144.8 1.5 3.5e-36 123.9 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AFI83016.1 - 6.2e-42 142.6 3.0 2.9e-34 117.8 0.1 3.1 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 AFI83016.1 - 1.3e-34 118.6 2.0 8.4e-34 116.0 0.7 2.3 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain Peroxin-3 PF04882.12 AFI83016.1 - 0.041 12.9 0.4 0.059 12.4 0.1 1.3 1 1 0 1 1 1 0 Peroxin-3 Fimbrial_CS1 PF04449.12 AFI83016.1 - 0.093 12.9 1.0 0.23 11.6 0.3 2.0 2 0 0 2 2 2 0 CS1 type fimbrial major subunit HemY_N PF07219.13 AFI83017.1 - 5.9e-31 106.8 3.7 5.9e-31 106.8 3.7 3.4 4 1 0 4 4 3 1 HemY protein N-terminus TPR_14 PF13428.6 AFI83017.1 - 4.6e-07 30.1 25.7 0.19 12.7 0.0 6.6 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 AFI83017.1 - 5e-06 26.9 26.4 0.0029 18.1 4.4 5.5 2 2 2 5 5 5 2 Tetratricopeptide repeat Methyltransf_9 PF08003.11 AFI83017.1 - 0.0018 17.3 0.3 0.0051 15.8 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1698) ANAPC3 PF12895.7 AFI83017.1 - 0.0074 16.5 10.7 1.9 8.8 0.1 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2897 PF11446.8 AFI83017.1 - 0.0089 15.9 4.1 0.011 15.6 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2897) TPR_MalT PF17874.1 AFI83017.1 - 0.011 15.1 0.6 0.011 15.1 0.6 3.3 2 1 1 3 3 3 0 MalT-like TPR region 7TM_GPCR_Sri PF10327.9 AFI83017.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri TPR_12 PF13424.6 AFI83017.1 - 0.017 15.4 3.5 0.017 15.4 3.5 5.4 3 2 2 5 5 5 0 Tetratricopeptide repeat DUF3566 PF12089.8 AFI83017.1 - 0.032 14.6 0.1 0.093 13.1 0.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) TPR_10 PF13374.6 AFI83017.1 - 0.16 11.9 12.7 0.58 10.1 0.3 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 AFI83017.1 - 0.16 12.2 16.3 3.2 8.1 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 AFI83017.1 - 0.37 10.9 14.2 0.89 9.7 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 AFI83017.1 - 0.95 10.2 0.1 0.95 10.2 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AFI83017.1 - 1.6 8.6 20.2 0.25 11.2 0.3 4.1 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_8 PF13181.6 AFI83017.1 - 4.5 7.7 5.9 13 6.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 AFI83017.1 - 9.8 6.9 23.4 3.3 8.4 0.6 6.0 5 1 0 6 6 6 0 Tetratricopeptide repeat HemX PF04375.14 AFI83018.1 - 9.2e-49 166.5 18.6 1.2e-48 166.1 18.6 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 AFI83018.1 - 0.002 17.9 2.7 0.0051 16.6 2.7 1.7 1 0 0 1 1 1 1 Septum formation initiator GPS2_interact PF15784.5 AFI83018.1 - 0.027 14.9 2.1 0.027 14.9 2.1 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain CENP-F_leu_zip PF10473.9 AFI83018.1 - 0.057 13.4 5.6 0.12 12.4 3.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3671 PF12420.8 AFI83018.1 - 0.077 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2749 PF10907.8 AFI83018.1 - 0.16 12.1 0.6 0.33 11.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) FtsL PF04999.13 AFI83018.1 - 0.3 11.1 3.6 1 9.4 0.4 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Spc24 PF08286.11 AFI83018.1 - 0.45 10.8 4.0 1.1 9.5 1.5 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.6 AFI83018.1 - 0.62 10.5 7.4 1.2 9.6 2.3 2.7 2 0 0 2 2 2 0 Snapin/Pallidin HEM4 PF02602.15 AFI83019.1 - 6.4e-38 130.4 0.0 7.4e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Porphobil_deam PF01379.20 AFI83020.1 - 4.5e-82 274.5 0.0 5.7e-82 274.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AFI83020.1 - 9.5e-21 74.0 0.0 2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lyase_1 PF00206.20 AFI83021.1 - 2.7e-80 270.1 0.0 3.6e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AFI83021.1 - 1.1e-24 87.0 0.2 2.4e-24 85.8 0.2 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF2914 PF11141.8 AFI83022.1 - 1.9e-20 72.3 1.2 2.6e-20 71.9 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2914) 2TM PF13239.6 AFI83023.1 - 0.69 10.3 4.4 0.87 9.9 4.4 1.2 1 0 0 1 1 1 0 2TM domain DUF3325 PF11804.8 AFI83024.1 - 4.4e-29 100.6 18.9 5.7e-29 100.2 18.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) NapE PF06796.11 AFI83024.1 - 0.24 10.9 4.8 0.5 9.9 4.8 1.6 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE PepSY_TM PF03929.16 AFI83025.1 - 1e-57 196.0 7.6 1.6e-57 195.4 7.6 1.3 1 0 0 1 1 1 1 PepSY-associated TM region Gram_pos_anchor PF00746.21 AFI83025.1 - 0.2 11.6 0.7 0.85 9.6 0.7 2.1 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4834 PF16118.5 AFI83025.1 - 2.2 9.3 3.7 8.9 7.4 2.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3649 PF12365.8 AFI83026.1 - 4.6e-09 35.8 0.1 4.6e-09 35.8 0.1 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3649) DUF3810 PF12725.7 AFI83026.1 - 0.16 11.3 2.6 0.18 11.1 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_U4 PF03419.13 AFI83026.1 - 1.2 8.4 9.6 1.2 8.3 9.6 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TonB_dep_Rec PF00593.24 AFI83027.1 - 1.8e-46 160.0 28.7 1.8e-46 160.0 28.7 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI83027.1 - 3.8e-13 49.9 0.9 3.8e-13 49.9 0.9 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI83027.1 - 1.4e-08 34.4 0.0 3.3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AFI83028.1 - 2.8e-23 82.4 0.1 5.7e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI83028.1 - 4.3e-09 36.1 8.2 7.9e-09 35.3 8.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) Sigma70_r2 PF04542.14 AFI83029.1 - 5e-13 48.6 1.2 9.3e-13 47.8 1.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AFI83029.1 - 1.9e-07 30.6 0.1 4e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI83029.1 - 3e-06 27.2 0.3 3.8e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AFI83029.1 - 0.00039 20.1 0.1 0.07 13.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AFI83029.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 MerR PF00376.23 AFI83029.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein FaeA PF04703.12 AFI83029.1 - 0.031 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein DUF134 PF02001.16 AFI83029.1 - 0.036 14.6 0.0 0.087 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF134 DUF3080 PF11279.8 AFI83029.1 - 0.05 12.8 0.6 0.075 12.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) Catalase PF00199.19 AFI83030.1 - 1.2e-177 590.8 0.1 1.5e-177 590.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AFI83030.1 - 1.3e-23 82.9 0.4 2.8e-23 81.9 0.4 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 AFI83030.1 - 1.2e-16 60.7 0.0 8.5e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 AFI83030.1 - 1.8e-06 27.9 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF748 PF05359.11 AFI83031.1 - 7.3e-18 65.2 0.2 3e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF748) Chorein_N PF12624.7 AFI83031.1 - 0.0095 16.1 0.1 0.029 14.5 0.1 1.9 1 1 0 1 1 1 1 N-terminal region of Chorein or VPS13 AsmA PF05170.14 AFI83031.1 - 0.01 14.7 1.4 0.04 12.7 0.9 2.2 1 1 1 2 2 2 0 AsmA family Rho_N PF07498.12 AFI83032.1 - 1.5e-06 28.0 3.4 1.6e-06 27.9 0.1 2.1 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain DUF4407 PF14362.6 AFI83032.1 - 1.6 8.0 6.8 1.5 8.1 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TonB_dep_Rec PF00593.24 AFI83033.1 - 1.9e-45 156.6 37.0 1.9e-45 156.6 37.0 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI83033.1 - 7.5e-15 55.4 0.9 7.5e-15 55.4 0.9 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI83033.1 - 3.3e-08 33.2 0.4 1.1e-07 31.5 0.4 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AFI83034.1 - 5.3e-19 68.6 0.5 9.7e-19 67.8 0.5 1.5 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI83034.1 - 7e-09 35.4 7.5 7e-09 35.4 7.5 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AFI83034.1 - 0.0019 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) HTH_47 PF16221.5 AFI83034.1 - 0.13 11.9 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 winged helix-turn-helix Sigma70_r4_2 PF08281.12 AFI83035.1 - 5.9e-14 51.5 0.0 1.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI83035.1 - 4e-13 48.9 0.3 7e-13 48.1 0.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AFI83035.1 - 4e-06 26.9 0.5 5.7e-06 26.3 0.5 1.2 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AFI83035.1 - 2.1e-05 24.0 0.0 4.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AFI83035.1 - 0.00076 19.2 0.0 0.0038 17.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain GerE PF00196.19 AFI83035.1 - 0.00084 18.8 0.7 0.0015 18.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 AFI83035.1 - 0.0023 17.5 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 AFI83035.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 AFI83035.1 - 0.012 16.1 0.1 0.037 14.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 AFI83035.1 - 0.012 15.4 0.1 0.047 13.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AFI83035.1 - 0.018 15.1 0.0 0.34 11.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 AFI83035.1 - 0.03 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_Mga PF08280.11 AFI83035.1 - 0.042 13.9 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_10 PF04967.12 AFI83035.1 - 0.043 13.6 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Sigma70_r3 PF04539.16 AFI83035.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 region 3 TnsD PF15978.5 AFI83035.1 - 0.066 12.2 1.1 0.17 10.9 0.0 1.9 2 1 0 2 2 2 0 Tn7-like transposition protein D HTH_3 PF01381.22 AFI83035.1 - 0.071 13.2 0.2 0.24 11.5 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 AFI83035.1 - 0.073 13.4 0.0 0.36 11.2 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AFI83035.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain ICMT PF04140.14 AFI83036.1 - 2e-13 50.5 0.3 2e-13 50.5 0.3 2.2 1 1 2 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 AFI83036.1 - 5.9e-11 42.7 0.2 5.9e-11 42.7 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase PepSY_TM PF03929.16 AFI83038.1 - 2.9e-52 178.1 5.5 3.4e-52 177.9 5.5 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY_TM_like_2 PF16357.5 AFI83038.1 - 9.9e-06 25.7 0.9 0.0012 18.8 0.0 2.7 2 1 0 2 2 2 1 Putative PepSY_TM-like DUF4405 PF14358.6 AFI83038.1 - 0.00022 21.7 8.6 0.0035 17.8 0.3 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 AFI83038.1 - 0.00042 20.0 4.8 0.0073 15.9 0.3 2.8 3 0 0 3 3 3 2 Prokaryotic cytochrome b561 DUF1129 PF06570.11 AFI83038.1 - 0.0082 15.7 0.5 0.02 14.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) TonB_dep_Rec PF00593.24 AFI83039.1 - 2e-50 173.0 19.1 3e-50 172.5 19.1 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83039.1 - 1.7e-13 51.1 0.2 2.9e-13 50.3 0.2 1.4 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain AbiGii_2 PF16873.5 AFI83039.1 - 0.14 10.9 0.0 2 7.1 0.0 2.0 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGii toxin HTH_18 PF12833.7 AFI83040.1 - 5.3e-18 65.1 0.0 9.7e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AFI83040.1 - 1.3e-13 50.7 0.0 3.8e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Esterase PF00756.20 AFI83043.1 - 2.5e-21 76.5 0.0 3.1e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AFI83043.1 - 1.5e-06 27.9 0.1 4.7e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AFI83043.1 - 6e-05 22.4 0.0 0.00015 21.1 0.0 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AFI83043.1 - 0.00049 20.0 0.0 0.00063 19.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 AFI83043.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AFI83043.1 - 0.073 13.7 0.0 0.25 11.9 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 AFI83043.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TonB_dep_Rec PF00593.24 AFI83044.1 - 2.1e-59 202.7 29.6 2.1e-59 202.7 29.6 1.7 2 1 1 3 3 3 1 TonB dependent receptor Plug PF07715.15 AFI83044.1 - 1.9e-21 76.7 0.1 6e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI83044.1 - 2.3e-08 33.7 1.1 9.8e-08 31.7 0.1 2.6 3 0 0 3 3 3 1 Secretin and TonB N terminus short domain FecR PF04773.13 AFI83045.1 - 4.8e-19 68.8 1.1 4.8e-19 68.8 1.1 1.8 3 0 0 3 3 3 1 FecR protein DUF4880 PF16220.5 AFI83045.1 - 3.5e-13 49.2 14.5 3.5e-13 49.2 14.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) DUF1681 PF07933.14 AFI83045.1 - 0.016 15.0 1.0 0.047 13.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Cthe_2159 PF14262.6 AFI83045.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 REV1_C PF16727.5 AFI83045.1 - 0.056 13.8 2.6 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain TACC_C PF05010.14 AFI83045.1 - 0.14 12.0 0.9 0.34 10.7 0.4 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sigma70_r4_2 PF08281.12 AFI83046.1 - 2.5e-19 68.7 1.9 5e-19 67.7 0.4 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI83046.1 - 3.2e-10 39.6 0.4 6.8e-10 38.6 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI83046.1 - 7.2e-09 35.0 0.9 1.9e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI83046.1 - 7.7e-08 32.4 0.1 2.2e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AFI83046.1 - 9.3e-07 28.5 0.5 2.9e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 AFI83046.1 - 0.00034 20.5 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_38 PF13936.6 AFI83046.1 - 0.00036 20.2 0.3 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain PCI PF01399.27 AFI83046.1 - 0.00039 20.9 0.5 0.0007 20.1 0.4 1.4 1 1 0 1 1 1 1 PCI domain HTH_24 PF13412.6 AFI83046.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 AFI83046.1 - 0.0015 18.0 0.0 0.0044 16.5 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_40 PF14493.6 AFI83046.1 - 0.003 18.0 0.1 0.011 16.2 0.0 1.9 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 AFI83046.1 - 0.0056 17.0 0.0 0.032 14.6 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 AFI83046.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 AFI83046.1 - 0.025 14.6 0.5 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix Spo0A_C PF08769.11 AFI83046.1 - 0.035 14.2 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal HTH_29 PF13551.6 AFI83046.1 - 0.047 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix TnsD PF15978.5 AFI83046.1 - 0.061 12.3 0.5 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 Tn7-like transposition protein D HTH_Tnp_4 PF13613.6 AFI83046.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_25 PF13413.6 AFI83046.1 - 0.064 13.1 0.2 0.41 10.5 0.0 2.4 2 2 1 3 3 3 0 Helix-turn-helix domain HTH_10 PF04967.12 AFI83046.1 - 0.074 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_36 PF13730.6 AFI83046.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.13 AFI83046.1 - 0.095 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 NUMOD1 domain PepSY_TM PF03929.16 AFI83048.1 - 9.7e-59 199.4 11.3 1.1e-58 199.2 11.3 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AFI83048.1 - 0.1 13.2 0.0 1.6 9.3 0.0 2.5 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain DUF2306 PF10067.9 AFI83048.1 - 0.5 10.6 10.5 2.2 8.5 0.3 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) MaAIMP_sms PF16951.5 AFI83048.1 - 5.2 6.9 7.5 28 4.6 2.6 2.6 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit TonB_dep_Rec PF00593.24 AFI83049.1 - 1.3e-42 147.2 19.5 1.3e-42 147.2 19.5 1.6 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83049.1 - 8.4e-15 55.3 2.0 2.3e-14 53.9 1.0 2.4 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI83049.1 - 1.7e-10 40.4 2.7 8e-10 38.3 0.1 2.5 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family STN PF07660.14 AFI83049.1 - 1.8e-09 37.3 0.1 5.7e-09 35.6 0.1 2.0 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain LptD PF04453.14 AFI83049.1 - 0.0022 17.3 1.8 0.94 8.6 0.0 3.5 2 1 0 3 3 3 1 LPS transport system D FecR PF04773.13 AFI83050.1 - 2e-21 76.4 0.1 2.9e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI83050.1 - 1.2e-13 50.7 13.9 2.9e-13 49.5 13.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) Sigma70_r4_2 PF08281.12 AFI83051.1 - 1e-15 57.1 0.6 5.1e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI83051.1 - 8.3e-13 47.9 0.2 1.4e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI83051.1 - 7e-07 28.7 0.1 2.3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AFI83051.1 - 9.6e-05 22.1 0.0 0.0019 17.9 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AFI83051.1 - 0.00055 19.9 0.0 0.00087 19.2 0.0 1.6 1 1 0 1 1 1 1 ECF sigma factor GerE PF00196.19 AFI83051.1 - 0.0038 16.7 0.0 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 AFI83051.1 - 0.02 14.4 0.2 0.048 13.2 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AFI83051.1 - 0.045 13.7 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 HTH domain TnsD PF15978.5 AFI83051.1 - 0.045 12.7 0.1 0.098 11.6 0.0 1.5 1 1 0 1 1 1 0 Tn7-like transposition protein D HTH_7 PF02796.15 AFI83051.1 - 0.15 12.2 0.1 0.42 10.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Fic PF02661.18 AFI83052.1 - 1.6e-11 45.0 0.0 5e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Fic/DOC family TonB_dep_Rec PF00593.24 AFI83055.1 - 4.5e-46 158.7 16.2 4.5e-46 158.7 16.2 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI83055.1 - 1.8e-19 70.3 0.8 3.6e-19 69.3 0.2 1.9 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI83055.1 - 5.2e-08 32.6 0.2 1.5e-07 31.1 0.2 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AFI83056.1 - 8.7e-17 61.5 0.5 1.7e-16 60.6 0.5 1.5 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI83056.1 - 3.9e-15 55.4 2.2 1.4e-14 53.7 2.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) V_ATPase_prox PF18274.1 AFI83056.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe Sigma70_r4_2 PF08281.12 AFI83057.1 - 1.2e-13 50.5 0.3 2e-13 49.8 0.1 1.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AFI83057.1 - 3.8e-08 32.7 0.0 7.4e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AFI83057.1 - 5.1e-07 29.3 0.4 2.1e-06 27.4 0.0 2.2 2 1 1 3 3 3 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AFI83057.1 - 1.3e-05 25.1 0.0 1.6e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_11 PF08279.12 AFI83057.1 - 0.00012 21.9 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain GerE PF00196.19 AFI83057.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_20 PF12840.7 AFI83057.1 - 0.00031 20.7 0.1 0.0025 17.8 0.1 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AFI83057.1 - 0.00077 19.5 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AFI83057.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_40 PF14493.6 AFI83057.1 - 0.0071 16.8 0.0 0.013 16.0 0.0 1.5 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AFI83057.1 - 0.008 15.7 0.6 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF1804 PF08822.11 AFI83057.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) Terminase_5 PF06056.12 AFI83057.1 - 0.083 12.8 0.2 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Spo0A_C PF08769.11 AFI83057.1 - 0.093 12.8 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal HTH_38 PF13936.6 AFI83057.1 - 0.12 12.2 0.7 0.32 10.8 0.0 2.2 3 1 0 3 3 3 0 Helix-turn-helix domain Sigma70_r2 PF04542.14 AFI83058.1 - 7.7e-07 28.8 0.1 8.6e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Sigma-70 region 2 TonB_dep_Rec PF00593.24 AFI83059.1 - 1.2e-67 229.9 27.7 1.8e-67 229.2 27.7 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83059.1 - 1.1e-20 74.2 0.5 3.9e-20 72.4 0.5 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI83059.1 - 1.8e-09 37.2 0.5 7.1e-09 35.3 0.5 2.1 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AFI83060.1 - 1.9e-15 57.3 0.2 3.1e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI83060.1 - 4.1e-11 42.6 14.8 4.1e-11 42.6 14.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) DDE_Tnp_ISL3 PF01610.17 AFI83060.1 - 0.049 13.3 1.1 0.11 12.2 1.1 1.5 1 0 0 1 1 1 0 Transposase Terminase_4 PF05119.12 AFI83060.1 - 0.11 13.0 0.9 0.25 11.8 0.2 2.0 2 0 0 2 2 2 0 Phage terminase, small subunit Sigma70_r4_2 PF08281.12 AFI83061.1 - 1.5e-16 59.8 0.2 7.2e-16 57.6 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI83061.1 - 3e-15 55.7 0.6 4.4e-15 55.2 0.6 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI83061.1 - 7.2e-08 31.8 0.0 1.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI83061.1 - 1.5e-05 24.9 1.1 3.4e-05 23.8 1.0 1.4 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AFI83061.1 - 0.00026 20.7 0.2 0.00085 19.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 AFI83061.1 - 0.0041 17.2 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 AFI83061.1 - 0.0095 15.9 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 HTH domain HTH_38 PF13936.6 AFI83061.1 - 0.026 14.3 0.4 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 AFI83061.1 - 0.028 14.7 0.0 0.081 13.3 0.0 1.9 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 AFI83061.1 - 0.043 13.9 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 AFI83061.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF148 PF02520.17 AFI83061.1 - 0.062 13.4 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF148 Med15_fungi PF05397.12 AFI83061.1 - 0.066 13.5 0.2 0.13 12.5 0.2 1.5 1 1 0 1 1 1 0 Mediator complex subunit 15 HTH_5 PF01022.20 AFI83061.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TonB_dep_Rec PF00593.24 AFI83062.1 - 5.9e-38 131.9 24.7 8.5e-38 131.4 24.7 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83062.1 - 1.8e-18 67.1 4.6 3.6e-18 66.1 3.2 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI83062.1 - 6.1e-05 22.2 0.1 0.00017 20.7 0.1 1.7 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family Autotransporter PF03797.19 AFI83062.1 - 0.00063 19.5 0.3 0.00063 19.5 0.3 3.3 4 0 0 4 4 4 1 Autotransporter beta-domain OMP_b-brl PF13505.6 AFI83062.1 - 0.013 15.7 0.8 0.013 15.7 0.8 3.3 2 1 0 3 3 3 0 Outer membrane protein beta-barrel domain FecR PF04773.13 AFI83063.1 - 7.8e-21 74.5 0.1 1.5e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI83063.1 - 3.2e-11 42.9 1.1 3.2e-11 42.9 1.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AFI83063.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Sigma70_r4_2 PF08281.12 AFI83064.1 - 2.2e-18 65.7 0.4 4.8e-18 64.6 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AFI83064.1 - 7.6e-12 44.6 0.1 1.6e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI83064.1 - 2.1e-06 27.8 0.2 2.5e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 ECF sigma factor GerE PF00196.19 AFI83064.1 - 4e-06 26.3 0.0 7.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AFI83064.1 - 5.9e-06 25.9 0.1 1.7e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 AFI83064.1 - 0.00053 19.5 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AFI83064.1 - 0.00055 19.9 0.1 0.00099 19.1 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AFI83064.1 - 0.0007 19.3 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AFI83064.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r2 PF04542.14 AFI83064.1 - 0.0084 15.9 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 HTH_11 PF08279.12 AFI83064.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain DUF1492 PF07374.11 AFI83064.1 - 0.011 15.9 0.1 0.014 15.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) DUF2774 PF11242.8 AFI83064.1 - 0.032 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) HTH_28 PF13518.6 AFI83064.1 - 0.035 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 AFI83064.1 - 0.047 14.1 0.1 0.17 12.4 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain TnsD PF15978.5 AFI83064.1 - 0.052 12.5 0.0 0.081 11.9 0.0 1.3 1 1 0 1 1 1 0 Tn7-like transposition protein D HBD PF18534.1 AFI83064.1 - 0.064 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Helical bundle domain HTH_Tnp_ISL3 PF13542.6 AFI83064.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_DeoR PF08220.12 AFI83064.1 - 0.093 12.5 0.5 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain NUMOD1 PF07453.13 AFI83064.1 - 0.21 11.9 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 NUMOD1 domain TerB PF05099.13 AFI83065.1 - 4.9e-36 123.8 5.5 6e-36 123.5 5.5 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF3335 PF11814.8 AFI83066.1 - 2.2e-85 285.4 0.1 2.9e-85 284.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family Acetyltransf_1 PF00583.25 AFI83066.1 - 6.8e-18 65.0 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AFI83066.1 - 5.1e-17 62.0 0.0 9.7e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AFI83066.1 - 2.3e-12 47.2 0.1 4.7e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AFI83066.1 - 1.5e-05 25.1 0.0 5.1e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AFI83066.1 - 2.3e-05 24.3 0.2 6.9e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Peptidase_C39_2 PF13529.6 AFI83066.1 - 6.8e-05 23.4 0.2 0.0026 18.3 0.2 2.2 1 1 0 1 1 1 1 Peptidase_C39 like family Acetyltransf_3 PF13302.7 AFI83066.1 - 0.0028 18.3 0.0 0.01 16.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 AFI83066.1 - 0.0074 16.1 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AFI83066.1 - 0.015 15.4 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Guanylate_cyc_2 PF09778.9 AFI83066.1 - 0.021 14.2 0.2 2.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Guanylylate cyclase Phytochelatin PF05023.14 AFI83066.1 - 0.035 13.3 0.2 0.077 12.2 0.2 1.5 1 1 0 1 1 1 0 Phytochelatin synthase Peptidase_C70 PF12385.8 AFI83066.1 - 0.037 14.0 0.2 0.87 9.6 0.0 2.3 1 1 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 Acetyltransf_15 PF17013.5 AFI83066.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 AFI83066.1 - 0.088 12.9 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 1 0 GCN5-related N-acetyl-transferase DUF2817 PF10994.8 AFI83067.1 - 6.8e-80 269.0 0.1 3.6e-79 266.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2817) RLAN PF14401.6 AFI83069.1 - 1.6e-50 170.6 0.0 3.2e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain RimK PF08443.11 AFI83069.1 - 9.8e-11 41.6 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 AFI83069.1 - 5.2e-09 35.9 0.0 8.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AFI83069.1 - 3.1e-05 24.1 0.0 0.00023 21.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AFI83069.1 - 9.7e-05 21.8 0.0 0.04 13.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 AFI83069.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PepSY_like PF11396.8 AFI83069.1 - 0.012 16.1 0.1 2.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like ATP-grasp_4 PF13535.6 AFI83069.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain TonB_dep_Rec PF00593.24 AFI83070.1 - 5.3e-38 132.1 30.9 7.6e-38 131.6 30.9 1.2 1 0 0 1 1 1 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AFI83070.1 - 3.2e-15 56.0 7.4 1.6e-14 53.7 7.4 1.9 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family Plug PF07715.15 AFI83070.1 - 1.5e-12 48.1 0.5 3.6e-12 46.8 0.5 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DnaJ_C PF01556.18 AFI83071.1 - 1.3e-36 125.9 0.0 1.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AFI83071.1 - 2.8e-28 97.8 1.6 9.1e-27 93.0 1.7 2.1 2 0 0 2 2 2 1 DnaJ domain NPCBM_assoc PF10633.9 AFI83071.1 - 0.0091 16.2 3.1 0.2 12.0 0.0 3.4 3 1 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Trypsin_2 PF13365.6 AFI83072.1 - 7.6e-32 111.3 1.3 1.5e-31 110.3 1.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AFI83072.1 - 2.3e-23 82.3 6.4 7.6e-16 58.2 1.3 3.4 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 AFI83072.1 - 8.5e-20 70.4 2.7 1e-08 34.9 0.4 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AFI83072.1 - 1e-16 61.0 0.8 1.8e-09 37.8 0.4 3.5 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AFI83072.1 - 1.5e-15 57.6 0.0 2.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_1 PF12812.7 AFI83072.1 - 2.9e-05 24.0 0.0 0.0009 19.2 0.0 2.7 2 0 0 2 2 2 1 PDZ-like domain Tricorn_PDZ PF14685.6 AFI83072.1 - 0.0012 18.7 0.3 0.29 11.1 0.2 2.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 AFI83072.1 - 0.0014 17.4 0.2 0.2 10.3 0.3 2.2 2 0 0 2 2 2 2 Peptidase S46 SseB_C PF14581.6 AFI83072.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain DUF1348 PF07080.11 AFI83073.1 - 4.3e-67 224.0 7.5 5e-67 223.7 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 AFI83073.1 - 1.1e-05 26.0 0.3 1.4e-05 25.6 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain TetR_N PF00440.23 AFI83074.1 - 3.4e-16 58.8 0.7 5.3e-16 58.1 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 AFI83074.1 - 0.0023 18.1 0.5 0.026 14.7 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase Rsm22 PF09243.10 AFI83074.1 - 0.012 14.9 0.1 0.017 14.4 0.0 1.2 1 1 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 HTH_10 PF04967.12 AFI83074.1 - 0.091 12.6 0.2 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain DUF5071 PF16804.5 AFI83074.1 - 0.11 12.7 0.0 19 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Ferritin PF00210.24 AFI83076.1 - 2.8e-37 127.8 4.1 3.4e-37 127.6 4.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain OAM_alpha PF16552.5 AFI83076.1 - 0.094 12.6 0.4 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit PemK_toxin PF02452.17 AFI83077.1 - 9.7e-08 32.4 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system JIP_LZII PF16471.5 AFI83077.1 - 0.018 15.2 3.9 0.05 13.8 3.9 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II YabA PF06156.13 AFI83077.1 - 0.035 14.7 0.8 0.086 13.5 0.8 1.6 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 AFI83077.1 - 0.051 13.8 2.4 2.6 8.3 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Viral_P18 PF04521.13 AFI83077.1 - 0.052 13.3 0.2 0.093 12.5 0.2 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Fungal_TACC PF12709.7 AFI83077.1 - 0.057 13.9 3.5 0.11 12.9 3.5 1.5 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins SWIRM-assoc_1 PF16495.5 AFI83077.1 - 0.095 12.7 3.7 5.4 7.1 4.4 2.3 2 0 0 2 2 2 0 SWIRM-associated region 1 DUF1542 PF07564.11 AFI83077.1 - 1.3 9.2 4.1 10 6.3 1.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) NTP_transf_3 PF12804.7 AFI83078.1 - 1e-24 87.7 0.0 1.5e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 AFI83078.1 - 2.6e-18 65.0 18.4 1.9e-07 30.6 0.1 5.3 2 1 3 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 AFI83078.1 - 6.8e-14 52.0 0.1 1.1e-13 51.4 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 AFI83078.1 - 2e-09 37.5 1.5 2.4e-09 37.3 0.4 1.7 2 1 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 AFI83078.1 - 1.1e-08 34.7 13.7 2e-05 24.2 0.0 4.7 3 2 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 AFI83078.1 - 2e-07 31.2 0.1 7.1e-07 29.4 0.0 1.8 1 1 0 2 2 2 1 Cytidylyltransferase CofC PF01983.16 AFI83078.1 - 3e-06 26.6 0.0 5.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Guanylyl transferase CofC like Fucokinase PF07959.12 AFI83078.1 - 0.0034 16.4 0.7 0.035 13.1 0.8 2.2 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 AFI83078.1 - 0.019 13.1 5.4 0.039 12.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Glu_syn_central PF04898.14 AFI83078.1 - 0.02 14.4 0.1 0.056 12.9 0.1 1.7 2 0 0 2 2 2 0 Glutamate synthase central domain ATP-synt_DE_N PF02823.16 AFI83079.1 - 9.7e-29 99.1 0.2 1.4e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AFI83079.1 - 1.6e-08 34.7 10.5 3.3e-08 33.7 10.5 1.6 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF1999 PF09390.10 AFI83079.1 - 0.034 13.8 0.6 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1999) ATP-synt_ab PF00006.25 AFI83080.1 - 4.9e-63 212.6 0.0 7.4e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AFI83080.1 - 7.5e-21 74.4 0.9 1.5e-20 73.5 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AFI83080.1 - 0.12 12.2 0.5 0.46 10.4 0.0 2.2 3 0 0 3 3 3 0 T3SS EscN ATPase C-terminal domain ATP-synt PF00231.19 AFI83081.1 - 2.3e-87 293.3 0.3 2.5e-87 293.1 0.3 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 AFI83082.1 - 1.4e-72 243.8 0.0 2e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AFI83082.1 - 1e-45 155.1 0.7 1.6e-45 154.5 0.7 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AFI83082.1 - 1.7e-15 57.2 0.7 4.6e-15 55.9 0.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AFI83082.1 - 1.6e-05 25.0 0.2 4.5e-05 23.5 0.2 1.8 1 1 0 1 1 1 1 HAS barrel domain ATPase PF06745.13 AFI83082.1 - 6.9e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 KaiC CSD2 PF17876.1 AFI83082.1 - 0.058 13.6 0.3 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Cold shock domain ATPase_2 PF01637.18 AFI83082.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea OSCP PF00213.18 AFI83083.1 - 1.5e-52 178.2 0.5 1.6e-52 178.1 0.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_B PF00430.18 AFI83084.1 - 2.5e-36 124.7 11.3 2.9e-36 124.5 11.3 1.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) ApoLp-III PF07464.11 AFI83084.1 - 0.002 18.3 1.0 0.0028 17.8 1.0 1.4 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) HrpE PF06188.12 AFI83084.1 - 0.0043 16.9 8.1 0.0056 16.6 8.1 1.3 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E DivIVA PF05103.13 AFI83084.1 - 0.0069 16.5 8.6 0.0069 16.5 8.6 2.1 1 1 1 2 2 2 2 DivIVA protein DUF3552 PF12072.8 AFI83084.1 - 0.01 15.3 11.3 0.01 15.3 11.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) V-ATPase_G_2 PF16999.5 AFI83084.1 - 0.051 14.0 19.4 0.086 13.3 19.4 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit REF PF05755.12 AFI83084.1 - 0.081 12.7 1.0 0.099 12.5 1.0 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Mt_ATP-synt_B PF05405.14 AFI83084.1 - 0.14 11.8 4.2 2.4 7.8 4.2 2.1 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) YMF19 PF02326.15 AFI83084.1 - 0.21 12.4 0.0 0.38 11.6 0.0 1.4 1 0 0 1 1 1 0 Plant ATP synthase F0 FliH PF02108.16 AFI83084.1 - 0.28 11.3 5.3 5 7.2 0.2 2.2 2 0 0 2 2 2 0 Flagellar assembly protein FliH DUF883 PF05957.13 AFI83084.1 - 0.31 11.7 14.9 1 10.0 6.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 AFI83084.1 - 1.2 9.7 6.2 9.2 6.9 6.2 2.3 1 1 0 1 1 1 0 YtxH-like protein V-ATPase_G PF03179.15 AFI83084.1 - 2 9.0 13.8 11 6.6 11.3 2.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TetR_C_11 PF16859.5 AFI83084.1 - 3.2 8.1 13.1 0.46 10.8 3.5 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ATP-synt_C PF00137.21 AFI83085.1 - 1.1e-08 35.3 9.9 1.3e-08 35.0 9.5 1.4 1 1 0 1 1 1 1 ATP synthase subunit C ATP-synt_A PF00119.20 AFI83086.1 - 2.5e-56 191.0 22.5 3.1e-56 190.7 22.5 1.1 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_I PF03899.15 AFI83087.1 - 5.4e-07 29.9 3.1 7e-07 29.6 3.1 1.2 1 0 0 1 1 1 1 ATP synthase I chain ParBc PF02195.18 AFI83088.1 - 9.5e-30 102.7 0.1 3.7e-29 100.9 0.1 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 AFI83088.1 - 8.2e-15 54.4 0.8 8.2e-15 54.4 0.8 2.7 3 0 0 3 3 3 1 HTH domain found in ParB protein HTH_3 PF01381.22 AFI83088.1 - 0.00019 21.4 0.5 0.0019 18.2 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix HTH_31 PF13560.6 AFI83088.1 - 0.00032 21.0 0.8 0.001 19.3 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI83088.1 - 0.002 17.9 1.4 0.0096 15.7 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_19 PF12844.7 AFI83088.1 - 0.0032 17.5 0.1 0.0086 16.1 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AFI83088.1 - 0.0066 16.1 0.4 0.074 12.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_37 PF13744.6 AFI83088.1 - 0.01 15.8 4.3 0.028 14.4 0.2 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AFI83088.1 - 0.021 14.3 1.3 0.17 11.4 0.3 2.9 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 AFI83088.1 - 0.028 14.4 1.9 0.05 13.6 0.2 2.3 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain KorB PF08535.10 AFI83088.1 - 0.12 12.4 0.1 0.46 10.6 0.0 2.0 1 1 1 2 2 2 0 KorB domain HTH_38 PF13936.6 AFI83088.1 - 0.18 11.6 3.9 0.24 11.2 0.2 2.9 4 0 0 4 4 4 0 Helix-turn-helix domain PSK_trans_fac PF07704.11 AFI83088.1 - 8.9 7.2 9.2 19 6.1 1.2 3.0 3 1 0 3 3 2 0 Rv0623-like transcription factor AAA_31 PF13614.6 AFI83089.1 - 5e-64 215.5 0.1 8.8e-64 214.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AFI83089.1 - 3.8e-29 101.3 0.5 1.2e-28 99.7 0.5 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AFI83089.1 - 2.1e-12 46.9 0.3 1.6e-10 40.7 0.3 2.3 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 AFI83089.1 - 3.8e-12 46.2 0.7 2e-11 43.9 0.7 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AFI83089.1 - 4.1e-10 39.5 0.0 2.5e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AFI83089.1 - 1e-09 38.3 0.5 1.7e-07 31.0 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AFI83089.1 - 1.3e-07 31.1 0.6 1e-06 28.1 0.5 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AFI83089.1 - 7.2e-05 22.2 1.3 0.0077 15.5 0.2 2.2 1 1 0 2 2 2 2 VirC1 protein ATP_bind_1 PF03029.17 AFI83089.1 - 0.00063 19.6 0.2 0.0018 18.1 0.2 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 AFI83089.1 - 0.00076 19.2 1.1 0.0085 15.7 0.5 2.4 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 AFI83089.1 - 0.00086 18.4 0.2 0.0021 17.1 0.2 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1611 PF07755.11 AFI83089.1 - 0.002 17.4 0.7 0.0052 16.1 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain CLP1_P PF16575.5 AFI83089.1 - 0.0048 16.7 0.1 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Methyltransf_24 PF13578.6 AFI83089.1 - 0.018 16.1 0.0 0.046 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA_25 PF13481.6 AFI83089.1 - 0.025 14.1 0.2 0.083 12.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain FTHFS PF01268.19 AFI83089.1 - 0.031 12.5 0.1 0.053 11.7 0.1 1.3 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase AAA_24 PF13479.6 AFI83089.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain GidB PF02527.15 AFI83090.1 - 5.1e-56 188.9 0.0 6e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 AFI83090.1 - 6e-05 22.7 0.1 0.00021 20.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AFI83090.1 - 0.00019 21.3 0.1 0.00036 20.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83090.1 - 0.0019 18.9 0.0 0.0031 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AFI83090.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 AFI83090.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_11 PF08241.12 AFI83090.1 - 0.027 15.1 0.0 0.045 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GIDA PF01134.22 AFI83091.1 - 8.8e-170 565.0 0.0 5.1e-169 562.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 AFI83091.1 - 2.3e-80 269.7 0.6 3.7e-80 269.0 0.6 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 AFI83091.1 - 4.1e-09 36.3 4.1 4.1e-09 36.3 4.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AFI83091.1 - 3.8e-08 32.9 5.7 1.2e-05 24.7 1.6 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AFI83091.1 - 2.4e-06 27.0 2.9 8.3e-06 25.2 2.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AFI83091.1 - 2e-05 23.9 1.3 0.00011 21.5 1.3 2.0 1 1 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 AFI83091.1 - 0.00053 18.8 0.9 0.008 14.9 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 AFI83091.1 - 0.00088 18.9 3.5 0.13 11.8 0.3 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AFI83091.1 - 0.01 15.1 0.3 0.02 14.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 AFI83091.1 - 0.014 14.7 0.4 0.035 13.4 0.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AFI83091.1 - 0.015 15.5 1.3 0.27 11.5 0.8 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AFI83091.1 - 0.042 13.1 0.1 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI83091.1 - 0.062 13.9 0.4 0.17 12.5 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AFI83091.1 - 0.77 9.7 2.5 0.73 9.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAGK_prokar PF01219.19 AFI83092.1 - 3.1e-32 110.4 2.2 3.7e-32 110.2 2.2 1.1 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase LGT PF01790.18 AFI83093.1 - 5.1e-82 274.7 11.5 5.8e-82 274.6 11.5 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Gcw_chp PF09694.10 AFI83094.1 - 9e-43 146.9 16.4 1.1e-42 146.6 16.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) Porin_4 PF13609.6 AFI83094.1 - 0.0046 16.8 22.3 0.031 14.0 22.3 2.0 1 1 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.6 AFI83094.1 - 0.013 15.6 21.1 0.011 15.9 19.4 1.7 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain P-II PF00543.22 AFI83095.1 - 1e-43 148.1 0.9 1.1e-43 147.9 0.9 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Cdc6_C PF09079.11 AFI83095.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Ammonium_transp PF00909.21 AFI83096.1 - 3.8e-99 332.1 36.5 9.2e-99 330.8 36.5 1.5 1 1 0 1 1 1 1 Ammonium Transporter Family Proton_antipo_N PF00662.20 AFI83096.1 - 0.067 13.3 2.3 0.16 12.0 0.0 2.7 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF3948 PF13134.6 AFI83096.1 - 0.26 11.0 3.6 2.3 8.0 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) URO-D PF01208.17 AFI83097.1 - 2.7e-139 464.2 0.0 3e-139 464.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Fer4_20 PF14691.6 AFI83098.1 - 3.4e-39 133.1 0.2 5e-39 132.6 0.2 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AFI83098.1 - 1.2e-26 93.6 0.4 2.1e-26 92.8 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI83098.1 - 7.2e-12 45.7 4.4 3.4e-06 27.5 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AFI83098.1 - 2.6e-07 30.2 0.2 0.0093 15.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 AFI83098.1 - 5.2e-07 28.5 0.0 8.1e-05 21.2 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like FAD_oxidored PF12831.7 AFI83098.1 - 2.1e-06 27.3 2.7 1.7e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AFI83098.1 - 1.8e-05 24.9 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AFI83098.1 - 3.3e-05 23.3 0.1 5.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 AFI83098.1 - 4.2e-05 23.9 0.4 0.041 14.3 0.0 2.5 3 0 0 3 3 2 2 Putative NAD(P)-binding Thi4 PF01946.17 AFI83098.1 - 7.8e-05 22.0 0.2 0.00019 20.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 AFI83098.1 - 0.0011 19.0 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 AFI83098.1 - 0.0014 17.4 0.3 0.0033 16.2 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 AFI83098.1 - 0.0019 17.3 0.7 0.33 10.0 0.2 3.1 3 1 1 4 4 4 1 FAD binding domain F420_oxidored PF03807.17 AFI83098.1 - 0.0061 17.1 0.0 2.1 9.0 0.0 3.2 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.19 AFI83098.1 - 0.02 13.6 0.1 1.8 7.2 0.0 2.5 3 0 0 3 3 3 0 Nitrogenase component 1 type Oxidoreductase DAO PF01266.24 AFI83098.1 - 0.024 14.2 3.0 0.5 9.9 0.4 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 AFI83098.1 - 0.024 14.0 0.0 0.54 9.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AFI83098.1 - 0.056 13.5 0.2 14 5.7 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 AFI83098.1 - 0.058 12.7 4.2 0.53 9.6 0.5 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AFI83098.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 AFI83098.1 - 0.093 11.9 0.0 4.9 6.2 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 AFI83098.1 - 0.12 12.4 0.6 0.64 10.0 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding IlvN PF07991.12 AFI83098.1 - 0.13 11.8 0.0 20 4.7 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 AFI83098.1 - 0.2 10.7 0.2 0.36 9.9 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A GATase_2 PF00310.21 AFI83099.1 - 2e-166 553.9 0.0 2.5e-166 553.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 AFI83099.1 - 5.7e-151 502.8 0.0 9.7e-151 502.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AFI83099.1 - 1e-104 350.0 0.0 2e-104 349.0 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 AFI83099.1 - 6.5e-77 257.4 8.3 1.1e-76 256.6 8.3 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 AFI83099.1 - 0.00014 21.0 0.1 0.00031 19.9 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AIRC PF00731.20 AFI83101.1 - 4.8e-63 211.2 0.9 5.4e-63 211.0 0.9 1.0 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 AFI83102.1 - 1.6e-54 184.1 0.1 2.5e-54 183.4 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AFI83102.1 - 1.3e-19 69.6 0.0 2.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 AFI83102.1 - 2.6e-08 33.7 0.4 5.4e-08 32.6 0.4 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 AFI83102.1 - 3.2e-05 23.6 0.1 0.00029 20.4 0.1 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 AFI83102.1 - 0.00042 19.7 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 AFI83102.1 - 0.056 13.9 0.2 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 AFI83102.1 - 0.065 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rdx PF10262.9 AFI83103.1 - 3.3e-25 88.1 0.0 3.7e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Rdx family Topoisom_bac PF01131.20 AFI83104.1 - 8.3e-131 436.8 0.5 1.1e-130 436.4 0.5 1.2 1 0 0 1 1 1 1 DNA topoisomerase zf-C4_Topoisom PF01396.19 AFI83104.1 - 1.1e-42 143.6 26.2 4.6e-15 55.1 2.8 4.4 4 0 0 4 4 4 3 Topoisomerase DNA binding C4 zinc finger Toprim PF01751.22 AFI83104.1 - 2.6e-28 98.2 0.2 5.6e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AFI83104.1 - 0.0079 16.6 0.3 0.073 13.6 0.0 2.4 3 0 0 3 3 3 1 Toprim domain zf-ribbon_3 PF13248.6 AFI83104.1 - 0.6 9.6 15.6 3.2 7.3 0.3 5.0 5 0 0 5 5 5 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 AFI83104.1 - 0.95 9.7 12.0 5.2 7.3 0.4 4.1 4 0 0 4 4 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf_Rg PF17915.1 AFI83104.1 - 3.9 6.9 8.3 8.1 5.9 0.1 3.9 4 0 0 4 4 4 0 Reverse gyrase zinc finger DUF494 PF04361.13 AFI83105.1 - 9.2e-53 178.2 3.7 1e-52 178.1 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF494) DNA_processg_A PF02481.15 AFI83106.1 - 8.6e-80 266.9 0.0 1.1e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AFI83106.1 - 2.1e-16 59.7 0.0 7.1e-16 58.1 0.0 2.0 1 0 0 1 1 1 1 DprA winged helix domain LDcluster4 PF18306.1 AFI83106.1 - 0.00015 21.4 1.1 0.00052 19.6 1.1 2.0 1 1 0 1 1 1 1 SLOG cluster4 family HHH_5 PF14520.6 AFI83106.1 - 0.0016 19.0 0.0 0.16 12.6 0.0 2.5 2 1 1 3 3 3 2 Helix-hairpin-helix domain cpYpsA PF12694.7 AFI83106.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Circularly permutated YpsA SLOG family HHH PF00633.23 AFI83106.1 - 0.025 14.4 0.0 0.58 10.1 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif LysM PF01476.20 AFI83107.1 - 1.1e-11 44.6 0.0 2.6e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 LysM domain FlgT_C PF16538.5 AFI83107.1 - 0.0092 16.5 0.0 0.064 13.8 0.0 2.3 2 0 0 2 2 2 1 Flagellar assembly protein T, C-terminal domain Cytochrom_C PF00034.21 AFI83108.1 - 8.6e-10 39.6 2.2 2e-09 38.4 2.2 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AFI83108.1 - 2.8e-09 37.1 0.6 4e-09 36.7 0.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF2780 PF11075.8 AFI83108.1 - 0.011 15.8 0.7 0.013 15.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Pep_deformylase PF01327.21 AFI83109.1 - 2e-50 170.5 0.0 2.4e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Formyl_trans_N PF00551.19 AFI83110.1 - 1.3e-43 148.8 0.0 2.9e-43 147.7 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 AFI83110.1 - 5.5e-30 103.6 0.9 1.4e-29 102.3 0.4 1.9 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain tRNA-synt_1c_C PF03950.18 AFI83110.1 - 0.16 11.9 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Methyltr_RsmB-F PF01189.17 AFI83111.1 - 1.6e-62 210.7 0.0 2.4e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 AFI83111.1 - 3.2e-19 69.5 0.2 9.9e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 NusB family Methyltransf_31 PF13847.6 AFI83111.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83111.1 - 6.6e-07 30.0 0.0 7.8e-06 26.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 AFI83111.1 - 1.8e-05 25.1 0.0 4.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 AFI83111.1 - 0.00024 21.2 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 AFI83111.1 - 0.00078 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AFI83111.1 - 0.00088 19.1 0.2 0.018 14.9 0.0 2.8 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83111.1 - 0.00092 19.9 0.0 0.022 15.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_5 PF01795.19 AFI83111.1 - 0.0029 17.2 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 MraW methylase family Methyltransf_24 PF13578.6 AFI83111.1 - 0.0074 17.3 0.0 0.45 11.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI83111.1 - 0.01 16.4 0.0 0.075 13.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 AFI83111.1 - 0.043 14.1 0.1 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) Cons_hypoth95 PF03602.15 AFI83111.1 - 0.053 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 AFI83111.1 - 0.053 13.1 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 AFI83111.1 - 0.065 13.2 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 AFI83111.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4390 PF14334.6 AFI83112.1 - 4.3e-46 156.3 0.3 4.9e-46 156.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4390) HATPase_c PF02518.26 AFI83113.1 - 1.2e-20 74.1 0.0 2.7e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AFI83113.1 - 1.9e-15 57.0 2.3 2.9e-15 56.4 0.0 2.6 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 AFI83113.1 - 1.4e-11 44.3 0.4 1.5e-10 40.9 0.0 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AFI83113.1 - 1.7e-08 34.2 0.0 4.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 GHKL domain PAS_7 PF12860.7 AFI83113.1 - 1.3e-05 25.4 0.1 5.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AFI83113.1 - 0.0037 17.2 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF1045 PF06299.12 AFI83113.1 - 0.016 15.2 1.3 0.1 12.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) HATPase_c_3 PF13589.6 AFI83113.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4199 PF13858.6 AFI83113.1 - 0.23 11.8 5.6 0.062 13.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1129 PF06570.11 AFI83113.1 - 9.3 5.7 7.2 0.59 9.6 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Response_reg PF00072.24 AFI83114.1 - 1.7e-32 111.9 0.3 3.7e-32 110.8 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AFI83114.1 - 2.3e-23 82.8 0.1 5.2e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 AFI83114.1 - 9.2e-17 61.3 0.2 1.9e-08 34.2 0.0 3.0 1 1 1 2 2 2 2 Sigma-54 interaction domain HTH_8 PF02954.19 AFI83114.1 - 1.5e-09 37.5 2.9 2.2e-09 37.0 1.6 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family UPF0175 PF03683.13 AFI83114.1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) AAA_16 PF13191.6 AFI83114.1 - 0.17 12.3 4.0 0.36 11.2 0.0 3.0 2 1 0 4 4 4 0 AAA ATPase domain TrkA_N PF02254.18 AFI83115.1 - 3.4e-50 169.2 5.6 1.1e-26 93.3 0.3 2.6 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 AFI83115.1 - 4.8e-25 87.2 1.9 1.4e-11 44.0 0.1 3.2 3 0 0 3 3 3 2 TrkA-C domain NAD_binding_7 PF13241.6 AFI83115.1 - 1.5e-14 54.3 1.0 8.9e-07 29.3 0.1 3.5 2 1 1 3 3 3 2 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AFI83115.1 - 6e-08 33.0 1.3 1.8e-05 25.0 0.1 2.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AFI83115.1 - 1.4e-06 28.8 6.9 0.0031 18.1 0.0 3.9 3 2 1 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 AFI83115.1 - 4.3e-06 26.2 0.1 0.061 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AFI83115.1 - 7.9e-06 25.3 0.8 0.0011 18.4 0.2 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 AFI83115.1 - 1.3e-05 25.2 2.0 0.0048 16.8 0.6 2.6 2 0 0 2 2 2 2 NAD(P)H-binding 3HCDH_N PF02737.18 AFI83115.1 - 3e-05 24.0 0.1 0.0009 19.2 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AFI83115.1 - 3.1e-05 24.4 2.9 0.018 15.6 0.0 3.2 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AFI83115.1 - 4.3e-05 23.2 0.5 0.00019 21.1 0.0 2.4 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 AFI83115.1 - 5e-05 23.0 0.1 0.00036 20.2 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AFI83115.1 - 0.00012 22.3 0.8 0.015 15.5 0.0 3.2 3 1 1 4 4 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AFI83115.1 - 0.00042 20.3 0.1 0.022 14.7 0.0 2.8 2 1 1 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 AFI83115.1 - 0.00043 20.4 1.3 0.23 11.5 0.1 2.7 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 AFI83115.1 - 0.00093 18.9 0.5 0.019 14.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase XdhC_C PF13478.6 AFI83115.1 - 0.0018 18.8 0.9 0.13 12.8 0.1 2.7 3 0 0 3 3 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 AFI83115.1 - 0.0035 16.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CEP170_C PF15308.6 AFI83115.1 - 0.0075 14.9 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 CEP170 C-terminus DUF1188 PF06690.11 AFI83115.1 - 0.0097 15.5 0.2 0.46 10.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) GFO_IDH_MocA PF01408.22 AFI83115.1 - 0.019 15.8 0.2 2 9.3 0.0 3.0 3 0 0 3 3 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_8 PF13450.6 AFI83115.1 - 0.021 15.1 0.4 0.17 12.1 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Rossmann-like PF10727.9 AFI83115.1 - 0.021 14.7 0.9 0.64 9.9 0.1 2.8 3 0 0 3 3 3 0 Rossmann-like domain ThiF PF00899.21 AFI83115.1 - 0.031 13.6 1.4 0.12 11.7 0.3 2.4 2 1 1 3 3 3 0 ThiF family Gp_dh_N PF00044.24 AFI83115.1 - 0.034 14.5 0.1 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Glyco_trans_4_4 PF13579.6 AFI83115.1 - 0.054 13.9 0.5 0.29 11.6 0.1 2.3 3 0 0 3 3 2 0 Glycosyl transferase 4-like domain Staph_opine_DH PF10100.9 AFI83115.1 - 0.12 11.0 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Staphylopine dehydrogenase Epimerase PF01370.21 AFI83115.1 - 0.12 11.8 0.8 0.95 8.9 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PglD_N PF17836.1 AFI83115.1 - 0.15 12.7 0.3 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 PglD N-terminal domain DUF179 PF02622.15 AFI83116.1 - 8.6e-50 168.8 0.1 9.6e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 RuvX PF03652.15 AFI83117.1 - 1.1e-40 139.1 0.0 1.3e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase Pribosyltran PF00156.27 AFI83118.1 - 1.8e-17 63.3 0.0 2.1e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AFI83118.1 - 0.0022 17.5 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AFI83118.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase OTCace_N PF02729.21 AFI83119.1 - 2.4e-40 137.9 0.6 2.4e-40 137.9 0.6 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AFI83119.1 - 7.3e-27 94.4 0.0 1.8e-26 93.1 0.0 1.6 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Paralemmin PF03285.15 AFI83119.1 - 0.11 12.0 0.0 0.67 9.5 0.0 1.8 2 0 0 2 2 2 0 Paralemmin Amidohydro_1 PF01979.20 AFI83120.1 - 1.3e-15 57.5 0.0 3.1e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AFI83120.1 - 8.1e-11 42.0 0.2 3.1e-08 33.5 0.0 3.2 2 1 2 4 4 4 2 Amidohydrolase family DHOase PF12890.7 AFI83120.1 - 2.8e-05 24.1 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 Dihydro-orotase-like DUF3012 PF11216.8 AFI83121.1 - 7.3e-20 70.7 1.1 1.1e-19 70.2 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3012) HAD_2 PF13419.6 AFI83122.1 - 0.00066 19.8 0.4 0.0011 19.0 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Copper-bind PF00127.20 AFI83123.1 - 1.2e-13 51.3 0.1 3.6e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family SieB PF14163.6 AFI83123.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B Ndc1_Nup PF09531.10 AFI83123.1 - 0.12 11.1 1.7 0.13 10.9 1.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SfsA_N PF17746.1 AFI83123.1 - 0.14 12.3 0.0 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 SfsA N-terminal OB domain Zip PF02535.22 AFI83123.1 - 0.15 11.2 1.8 0.26 10.5 1.0 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4834 PF16118.5 AFI83123.1 - 0.18 12.8 1.9 0.7 10.9 1.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Hamartin PF04388.12 AFI83123.1 - 0.23 10.1 8.4 0.27 9.9 8.4 1.1 1 0 0 1 1 1 0 Hamartin protein MacB_PCD PF12704.7 AFI83123.1 - 0.34 11.2 4.3 0.71 10.2 4.0 1.6 1 1 1 2 2 2 0 MacB-like periplasmic core domain SID-1_RNA_chan PF13965.6 AFI83123.1 - 0.73 8.2 1.6 0.95 7.8 1.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 T2SSM PF04612.12 AFI83123.1 - 0.98 9.5 10.4 1.7 8.7 0.1 2.4 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M PA26 PF04636.13 AFI83123.1 - 1.9 7.3 7.3 2.4 7.0 7.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SBE2 PF17076.5 AFI83123.1 - 2.3 6.3 7.1 2.7 6.1 7.1 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation GREB1 PF15782.5 AFI83123.1 - 2.8 4.9 6.6 3.1 4.8 6.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 AFI83123.1 - 4.3 6.7 4.9 5.7 6.3 4.9 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BAF1_ABF1 PF04684.13 AFI83123.1 - 5.6 5.9 13.1 7.3 5.5 13.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IDH PF03971.14 AFI83124.1 - 0 1227.4 0.1 0 1227.2 0.1 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase ABC_tran PF00005.27 AFI83125.1 - 2.9e-31 108.8 0.0 4.3e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AFI83125.1 - 6.5e-07 29.4 0.0 2.8e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AFI83125.1 - 8.5e-06 25.8 0.4 0.0014 18.5 0.1 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI83125.1 - 0.00013 21.5 0.0 0.051 13.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AFI83125.1 - 0.0005 20.6 0.0 0.00079 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 AFI83125.1 - 0.00075 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AFI83125.1 - 0.0018 18.7 0.1 0.0037 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AFI83125.1 - 0.0032 17.9 0.2 0.0063 16.9 0.2 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI83125.1 - 0.0037 16.7 0.0 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AFI83125.1 - 0.0039 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFI83125.1 - 0.0046 16.9 0.1 0.0077 16.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 AFI83125.1 - 0.0047 16.9 0.1 0.0085 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AFI83125.1 - 0.007 16.6 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AFI83125.1 - 0.008 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 AFI83125.1 - 0.01 15.0 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 AFI83125.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 AFI83125.1 - 0.026 14.3 0.1 0.076 12.8 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 AFI83125.1 - 0.038 13.6 0.2 0.094 12.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFI83125.1 - 0.044 14.3 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AFI83125.1 - 0.046 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 AFI83125.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 AFI83125.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 AFI83125.1 - 0.089 13.0 0.3 0.31 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AFI83125.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AFI83125.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AFI83125.1 - 0.18 11.3 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 AFI83125.1 - 0.2 11.7 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit BPD_transp_1 PF00528.22 AFI83126.1 - 6.4e-30 104.3 41.6 2.8e-20 72.8 14.8 3.2 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component SBP_bac_6 PF13343.6 AFI83127.1 - 4.2e-12 46.0 0.0 5.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AFI83127.1 - 2.2e-08 34.1 0.4 1.7e-07 31.2 0.4 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AFI83127.1 - 1e-05 25.7 0.0 6.3e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AFI83127.1 - 0.0033 17.3 0.0 0.2 11.4 0.0 2.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein TAT_signal PF10518.9 AFI83127.1 - 0.0059 16.4 0.4 0.0059 16.4 0.4 2.2 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Arch_fla_DE PF04659.13 AFI83128.1 - 0.07 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Archaeal flagella protein 2_5_RNA_ligase2 PF13563.6 AFI83128.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily MtrG PF04210.13 AFI83128.1 - 0.24 11.3 0.7 8.7 6.3 0.1 2.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G NPV_P10 PF05531.12 AFI83128.1 - 0.55 10.7 3.8 14 6.3 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TonB_dep_Rec PF00593.24 AFI83130.1 - 4.2e-40 139.0 26.8 6e-40 138.5 26.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83130.1 - 2.5e-13 50.5 0.1 9.7e-13 48.6 0.1 2.1 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI83130.1 - 1.7e-06 27.3 10.8 0.00029 19.9 0.3 3.4 3 1 0 3 3 3 2 Outer membrane protein beta-barrel family Copper-bind PF00127.20 AFI83132.1 - 9.1e-17 61.3 0.3 1.4e-16 60.8 0.3 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family AI-2E_transport PF01594.16 AFI83133.1 - 8.7e-77 258.5 44.8 1e-76 258.2 44.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter Cyt_b-c1_8 PF10890.8 AFI83133.1 - 0.048 14.1 0.2 0.57 10.6 0.0 2.8 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 HlyD_D23 PF16576.5 AFI83136.1 - 2.9e-19 69.1 1.2 4.1e-19 68.7 1.2 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI83136.1 - 1.7e-13 51.2 0.1 4.8e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 HlyD family secretion protein HlyD PF00529.20 AFI83136.1 - 0.026 14.4 0.1 0.84 9.6 0.0 2.3 2 1 0 2 2 2 0 HlyD membrane-fusion protein of T1SS OEP PF02321.18 AFI83136.1 - 1.6 8.5 18.0 3.1 7.6 18.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4398 PF14346.6 AFI83136.1 - 4.6 7.9 22.8 8.8 7.0 22.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Phycobilisome PF00502.19 AFI83136.1 - 8.8 6.2 8.4 6.8 6.6 1.4 2.2 1 1 1 2 2 2 0 Phycobilisome protein ACR_tran PF00873.19 AFI83137.1 - 5.5e-186 620.2 11.9 1.3e-185 619.0 11.9 1.5 1 1 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI83137.1 - 4.6e-22 78.4 29.6 3.6e-11 42.6 5.6 2.4 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AFI83137.1 - 3.8e-06 26.4 29.5 0.0049 16.3 11.3 2.5 2 0 0 2 2 2 2 Protein export membrane protein DUF3215 PF11503.8 AFI83137.1 - 0.13 12.1 0.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) Lipocalin_2 PF08212.12 AFI83138.1 - 1.9e-41 141.4 0.0 2.2e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 AFI83138.1 - 4.4e-12 46.4 0.0 5.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family ApoM PF11032.8 AFI83138.1 - 0.17 11.6 0.0 5.8 6.6 0.0 2.1 2 0 0 2 2 2 0 ApoM domain DUF2805 PF10985.8 AFI83139.1 - 1.6e-34 118.1 0.0 1.9e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2805) MAPEG PF01124.18 AFI83140.1 - 5e-16 58.8 7.1 5.9e-16 58.6 7.1 1.1 1 0 0 1 1 1 1 MAPEG family FBPase PF00316.20 AFI83141.1 - 5.3e-66 221.7 0.0 6.8e-66 221.3 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 AFI83141.1 - 0.02 14.4 0.0 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 Inositol monophosphatase family GXGXG PF01493.19 AFI83142.1 - 1.8e-17 63.6 13.5 2.7e-17 63.0 13.5 1.2 1 0 0 1 1 1 1 GXGXG motif FTR_C PF02741.15 AFI83143.1 - 3.5e-66 221.8 0.6 5.7e-66 221.1 0.1 1.5 2 0 0 2 2 2 1 FTR, proximal lobe FTR PF01913.18 AFI83143.1 - 8.9e-62 207.2 0.0 1.3e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase Amidohydro_3 PF07969.11 AFI83144.1 - 3.3e-59 201.6 2.5 4e-59 201.3 2.5 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AFI83144.1 - 2.3e-06 27.2 1.1 0.033 13.5 0.3 2.6 3 0 0 3 3 3 2 Amidohydrolase family TPP_enzyme_M PF00205.22 AFI83145.1 - 0.03 14.0 0.1 0.13 12.0 0.0 2.2 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain SPOR PF05036.13 AFI83147.1 - 1.5e-17 63.7 0.1 3.1e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 Sporulation related domain eIF_4EBP PF05456.11 AFI83147.1 - 0.011 15.7 0.4 0.015 15.2 0.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DALR_1 PF05746.15 AFI83148.1 - 2.7e-33 114.6 0.4 5.1e-33 113.8 0.4 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AFI83148.1 - 8.2e-28 96.8 0.2 2.1e-27 95.5 0.2 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1d PF00750.19 AFI83148.1 - 7.2e-25 87.7 1.9 5.6e-12 45.3 0.4 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1g PF09334.11 AFI83148.1 - 0.0004 19.3 0.1 0.41 9.3 0.0 3.5 3 1 1 4 4 4 2 tRNA synthetases class I (M) Ceramidse_alk_C PF17048.5 AFI83148.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal PriA_3primeBD PF17764.1 AFI83149.1 - 1.1e-27 95.8 0.1 3.7e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 AFI83149.1 - 3e-21 76.0 0.1 1.3e-20 74.0 0.1 2.2 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain DEAD PF00270.29 AFI83149.1 - 2e-14 53.8 0.3 8.1e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AFI83149.1 - 1.5e-13 51.1 0.0 3.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AFI83149.1 - 5.9e-11 42.7 3.2 1.2e-05 25.6 0.1 3.7 3 1 1 4 4 4 2 Helicase conserved C-terminal domain PriA_CRR PF18319.1 AFI83149.1 - 6.6e-08 32.4 8.1 6.6e-08 32.4 8.1 2.8 3 0 0 3 3 2 1 PriA DNA helicase Cys-rich region (CRR) domain PIF1 PF05970.14 AFI83149.1 - 0.0006 19.1 0.2 0.0034 16.6 0.1 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 AFI83149.1 - 0.0017 18.1 0.1 0.008 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mtr2 PF10429.9 AFI83149.1 - 0.0031 17.5 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 T2SSE PF00437.20 AFI83149.1 - 0.0084 15.2 0.3 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_11 PF13086.6 AFI83149.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NOB1_Zn_bind PF08772.11 AFI83149.1 - 0.032 14.4 8.6 1.1 9.5 6.4 3.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like NOA36 PF06524.12 AFI83149.1 - 0.042 13.2 4.0 0.068 12.5 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_19 PF13245.6 AFI83149.1 - 0.052 13.9 0.1 0.27 11.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 AFI83149.1 - 0.085 13.2 1.2 0.87 10.0 0.0 2.9 3 1 0 3 3 2 0 AAA ATPase domain DUF2183 PF09949.9 AFI83149.1 - 0.097 13.0 0.1 3.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) AAA_22 PF13401.6 AFI83149.1 - 0.12 12.7 0.6 0.91 9.8 0.0 2.8 2 2 0 2 2 2 0 AAA domain Haemocyan_bet_s PF14830.6 AFI83149.1 - 0.12 12.4 0.2 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Haemocyanin beta-sandwich zinc-ribbons_6 PF07191.12 AFI83149.1 - 0.29 11.2 10.0 0.032 14.2 5.6 1.7 2 0 0 2 2 1 0 zinc-ribbons A2L_zn_ribbon PF08792.10 AFI83149.1 - 0.47 10.2 10.6 0.34 10.7 5.6 2.8 2 1 0 2 2 2 0 A2L zinc ribbon domain HypA PF01155.19 AFI83149.1 - 1.1 9.3 9.4 3.8 7.6 8.5 2.4 2 1 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1272 PF06906.11 AFI83149.1 - 7.8 6.7 7.6 17 5.6 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Na_Pi_cotrans PF02690.15 AFI83150.1 - 5.8e-48 162.5 33.0 8.1e-41 139.4 11.8 2.3 2 0 0 2 2 2 2 Na+/Pi-cotransporter UPF0542 PF15086.6 AFI83150.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DHFR_1 PF00186.19 AFI83151.1 - 8.1e-62 207.7 0.0 9e-62 207.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase PsiE PF06146.12 AFI83152.1 - 2.3e-10 40.7 0.0 2.7e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate-starvation-inducible E TonB_C PF03544.14 AFI83152.1 - 0.17 12.4 0.0 0.2 12.1 0.0 1.1 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Pentapeptide PF00805.22 AFI83154.1 - 4.3e-13 48.6 1.5 1.7e-06 27.5 1.2 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AFI83154.1 - 5.9e-06 26.4 0.0 8.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AFI83154.1 - 0.00012 22.2 0.2 0.0056 16.8 0.1 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) TatC PF00902.18 AFI83155.1 - 8.5e-65 218.4 21.5 9.8e-65 218.3 21.5 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF1565 PF07602.11 AFI83155.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) DUF4321 PF14209.6 AFI83155.1 - 1.6 8.7 9.6 3.7 7.5 0.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4321) MttA_Hcf106 PF02416.16 AFI83156.1 - 4e-07 29.2 3.9 7.8e-07 28.3 3.8 1.7 1 1 0 1 1 1 1 mttA/Hcf106 family MttA_Hcf106 PF02416.16 AFI83157.1 - 3e-16 58.5 0.5 4.9e-16 57.8 0.5 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family DUF4834 PF16118.5 AFI83157.1 - 0.006 17.5 0.1 0.0071 17.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) OFeT_1 PF16955.5 AFI83157.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF1980 PF09323.10 AFI83157.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ctr PF04145.15 AFI83157.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.0 1 0 0 1 1 1 0 Ctr copper transporter family Lectin_N PF03954.14 AFI83157.1 - 1.1 9.0 4.3 0.24 11.2 0.4 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DcpS_C PF11969.8 AFI83158.1 - 8.5e-25 87.5 0.0 9.5e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 AFI83158.1 - 2.1e-24 86.1 0.1 2.4e-24 85.9 0.1 1.0 1 0 0 1 1 1 1 HIT domain PRA-PH PF01503.17 AFI83159.1 - 3.1e-15 56.4 0.2 3.4e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 AFI83159.1 - 0.005 17.0 0.1 0.0089 16.2 0.1 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DD_K PF12121.8 AFI83159.1 - 2.7 8.2 4.3 0.61 10.3 0.6 1.9 2 0 0 2 2 2 0 Dermaseptin PRA-CH PF01502.18 AFI83160.1 - 5.2e-34 115.9 0.4 6.9e-34 115.5 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase His_biosynth PF00977.21 AFI83161.1 - 4e-92 307.8 1.6 4.5e-92 307.7 1.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AFI83161.1 - 9.8e-09 34.7 0.4 8e-06 25.2 0.2 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 AFI83161.1 - 5.7e-07 29.1 1.9 0.0059 15.9 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 AFI83161.1 - 2.3e-06 27.2 8.6 0.0014 18.1 1.9 2.1 1 1 1 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 AFI83161.1 - 0.00019 20.9 0.3 0.16 11.3 0.1 2.5 2 0 0 2 2 2 2 Thiamine monophosphate synthase DHO_dh PF01180.21 AFI83161.1 - 0.00024 20.4 0.2 0.039 13.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 AFI83161.1 - 0.00047 19.6 0.2 0.0093 15.4 0.0 2.2 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 AFI83161.1 - 0.0017 17.5 4.8 0.11 11.5 0.5 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AFI83161.1 - 0.0037 16.3 7.9 0.026 13.6 0.7 2.4 2 1 0 2 2 2 2 FMN-dependent dehydrogenase Trp_syntA PF00290.20 AFI83161.1 - 0.011 14.6 0.2 0.018 13.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain PcrB PF01884.17 AFI83161.1 - 0.031 13.7 0.0 0.086 12.3 0.0 1.7 2 0 0 2 2 2 0 PcrB family IGPS PF00218.21 AFI83161.1 - 0.1 11.8 0.1 1.1 8.3 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 AFI83161.1 - 0.15 11.2 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) His_biosynth PF00977.21 AFI83162.1 - 2.1e-79 266.2 1.4 2.4e-79 266.0 1.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AFI83162.1 - 2.2e-10 40.1 1.1 4.3e-06 26.1 0.2 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AFI83162.1 - 0.00012 21.6 1.6 0.0049 16.3 0.2 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase G3P_antiterm PF04309.12 AFI83162.1 - 0.00097 18.6 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 AFI83162.1 - 0.0014 18.0 0.1 0.056 12.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine monophosphate synthase IMPDH PF00478.25 AFI83162.1 - 0.0021 17.1 1.7 0.22 10.5 0.3 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 AFI83162.1 - 0.0069 15.6 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase DeoC PF01791.9 AFI83162.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 DeoC/LacD family aldolase PEP_mutase PF13714.6 AFI83162.1 - 0.022 14.2 0.1 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase PcrB PF01884.17 AFI83162.1 - 0.04 13.4 0.2 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 PcrB family DUF561 PF04481.12 AFI83162.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF561) GATase PF00117.28 AFI83163.1 - 2.5e-18 66.5 0.0 2.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AFI83163.1 - 0.00029 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 AFI83163.1 - 0.00092 19.0 0.2 0.11 12.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C26 SNO PF01174.19 AFI83163.1 - 0.012 15.4 0.2 0.17 11.7 0.2 2.0 1 1 0 1 1 1 0 SNO glutamine amidotransferase family NTP_transf_3 PF12804.7 AFI83163.1 - 0.069 13.5 0.0 16 5.8 0.0 2.1 1 1 1 2 2 2 0 MobA-like NTP transferase domain IGPD PF00475.18 AFI83164.1 - 2.8e-66 222.3 0.6 4.4e-66 221.6 0.6 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF916 PF06030.12 AFI83164.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) cNMP_binding PF00027.29 AFI83165.1 - 1.3e-14 54.0 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AFI83165.1 - 2.2e-14 53.2 0.7 4.5e-14 52.2 0.7 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AFI83165.1 - 4.1e-13 48.7 0.7 7.4e-13 47.9 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family OmpW PF03922.14 AFI83166.1 - 1.5e-07 31.5 0.0 1.5e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 OmpW family OmpW PF03922.14 AFI83167.1 - 1.1e-08 35.3 0.1 1.2e-08 35.0 0.1 1.0 1 0 0 1 1 1 1 OmpW family MurJ PF03023.14 AFI83168.1 - 7.6e-152 506.0 27.6 1e-151 505.6 27.6 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AFI83168.1 - 2.6e-11 43.8 34.5 1.3e-10 41.5 18.8 4.5 3 2 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 AFI83168.1 - 5e-07 29.5 16.5 3.2e-05 23.6 2.6 3.9 4 1 0 4 4 4 2 MatE SecE PF00584.20 AFI83168.1 - 3.8 7.5 8.3 1.7 8.7 0.3 3.7 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex SCO1-SenC PF02630.14 AFI83169.1 - 0.00059 19.8 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Redoxin PF08534.10 AFI83169.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 AFI83169.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family LysR_substrate PF03466.20 AFI83170.1 - 1.2e-42 145.7 1.5 1.5e-42 145.4 1.5 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AFI83170.1 - 8.1e-17 60.9 0.1 1.7e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Rubredoxin PF00301.20 AFI83171.1 - 1.2e-23 82.8 4.6 1.3e-23 82.7 4.6 1.0 1 0 0 1 1 1 1 Rubredoxin zf-RanBP PF00641.18 AFI83171.1 - 0.002 17.4 4.4 0.11 11.8 0.7 2.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-C2H2_3 PF13878.6 AFI83171.1 - 0.014 15.2 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO OrfB_Zn_ribbon PF07282.11 AFI83171.1 - 0.059 13.3 0.5 8.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PHD_4 PF16866.5 AFI83171.1 - 0.066 13.3 7.7 0.36 10.9 7.7 1.9 1 1 0 1 1 1 0 PHD-finger HalOD2 PF18547.1 AFI83171.1 - 0.083 12.8 1.1 6.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Halobacterial output domain 2 Rubredoxin_2 PF18073.1 AFI83171.1 - 0.14 11.9 5.0 5.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain RbpA PF13397.6 AFI83171.1 - 0.39 11.4 2.3 0.46 11.1 0.4 1.9 1 1 1 2 2 2 0 RNA polymerase-binding protein Zn_ribbon_SprT PF17283.2 AFI83171.1 - 0.65 10.0 3.6 13 5.8 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-MIZ PF02891.20 AFI83171.1 - 1.1 9.1 5.6 6.4 6.6 1.2 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger SMC_N PF02463.19 AFI83172.1 - 5.7e-23 81.5 0.0 2.7e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AFI83172.1 - 6.1e-11 42.7 0.1 1.8e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AFI83172.1 - 1.2e-07 31.8 0.1 2.1e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AFI83172.1 - 2e-07 31.7 0.1 5.3e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AFI83172.1 - 1.5e-06 27.8 0.2 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.6 AFI83172.1 - 0.00041 19.1 0.8 0.1 11.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 AFI83172.1 - 0.00068 20.2 0.0 0.014 15.9 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA PF00004.29 AFI83172.1 - 0.0071 16.8 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2813 PF11398.8 AFI83172.1 - 0.0095 15.2 0.2 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_16 PF13191.6 AFI83172.1 - 0.022 15.2 0.3 0.11 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 AFI83172.1 - 0.04 13.1 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_27 PF13514.6 AFI83172.1 - 0.05 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AFI83172.1 - 0.14 11.6 0.1 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 AFI83172.1 - 0.14 12.4 0.1 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AFI83172.1 - 0.19 11.5 0.4 1.5 8.5 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain DNA_gyraseB PF00204.25 AFI83173.1 - 4.6e-59 198.8 0.1 4.6e-59 198.8 0.1 2.2 3 0 0 3 3 3 1 DNA gyrase B GyrB_insert PF18053.1 AFI83173.1 - 4e-49 166.7 0.0 7.6e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain DNA_gyraseB_C PF00986.21 AFI83173.1 - 3.5e-30 104.0 0.5 7.5e-30 102.9 0.5 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AFI83173.1 - 1.4e-22 80.3 0.1 2.9e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AFI83173.1 - 1.4e-18 67.0 0.0 4.2e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AFI83173.1 - 0.0017 18.2 0.2 0.005 16.7 0.2 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAC3 PF12209.8 AFI83173.1 - 0.0025 18.0 0.3 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Peptidase_S8 PF00082.22 AFI83173.1 - 0.047 12.9 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 Subtilase family Pyr_redox_2 PF07992.14 AFI83174.1 - 2.2e-59 201.1 0.1 2.5e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI83174.1 - 1.5e-14 54.3 0.8 4.7e-09 36.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AFI83174.1 - 0.00015 21.8 0.1 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 AFI83174.1 - 0.0055 15.9 0.1 2.5 7.2 0.1 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AFI83174.1 - 0.013 15.7 1.0 2 8.7 0.2 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AFI83174.1 - 0.025 13.6 0.4 0.86 8.6 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AFI83174.1 - 0.08 12.2 0.6 2.4 7.3 0.1 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AFI83174.1 - 0.093 13.0 0.1 22 5.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain BssB_TutG PF18512.1 AFI83174.1 - 0.093 12.6 0.2 18 5.3 0.0 2.3 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit ThiF PF00899.21 AFI83174.1 - 0.17 11.2 1.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 ThiF family DAO PF01266.24 AFI83174.1 - 0.47 10.0 8.4 2.8 7.5 0.1 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase Flavoprotein PF02441.19 AFI83175.1 - 1.2e-11 44.6 0.0 3.4e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Flavoprotein Pterin_bind PF00809.22 AFI83176.1 - 0.0005 19.8 0.1 0.0017 18.0 0.1 1.8 1 1 0 1 1 1 1 Pterin binding enzyme DUF4346 PF14251.6 AFI83176.1 - 0.0049 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4346) Amdase PF17645.1 AFI83176.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase DUF447 PF04289.12 AFI83177.1 - 2.1e-45 154.6 0.0 2.4e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 AFI83177.1 - 0.00051 20.2 0.0 0.00088 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase 4HFCP_synth PF04476.13 AFI83178.1 - 7.9e-46 156.6 0.0 8.9e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 4-HFC-P synthase Meth_synt_2 PF01717.18 AFI83179.1 - 9.2e-161 534.5 0.1 1.6e-153 510.7 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 AFI83179.1 - 1.5e-125 418.9 0.0 2.8e-117 391.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 AFI83179.1 - 0.0034 16.6 0.4 1.6 7.8 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Toprim PF01751.22 AFI83179.1 - 0.11 12.8 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Toprim domain LysR_substrate PF03466.20 AFI83180.1 - 2.4e-26 92.4 0.7 2.8e-26 92.2 0.1 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AFI83180.1 - 1.1e-18 67.0 1.8 1.9e-18 66.1 1.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 AFI83180.1 - 0.00067 19.7 0.6 0.011 15.9 0.3 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_30 PF13556.6 AFI83180.1 - 0.0071 16.1 0.7 0.017 14.9 0.7 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 AFI83180.1 - 0.029 14.2 0.1 0.076 12.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AFI83180.1 - 0.12 12.4 1.5 0.28 11.3 0.4 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Response_reg PF00072.24 AFI83181.1 - 8.2e-43 145.1 1.1 4.6e-25 88.0 0.2 2.0 2 0 0 2 2 2 2 Response regulator receiver domain Glyco_hydro_49 PF03718.13 AFI83181.1 - 0.00053 20.0 0.0 0.0032 17.5 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 49 BRCT_3 PF18428.1 AFI83181.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1350 PF07082.11 AFI83181.1 - 0.097 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) DJ-1_PfpI PF01965.24 AFI83182.1 - 7.3e-43 146.2 0.0 8.3e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 AFI83182.1 - 0.00063 19.4 0.0 0.0009 18.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 AFI83182.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like YAcAr PF10686.9 AFI83182.1 - 0.052 13.5 0.1 0.91 9.5 0.1 2.4 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Peptidase_S41 PF03572.18 AFI83183.1 - 1.3e-58 197.2 0.3 1.8e-58 196.8 0.3 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 AFI83183.1 - 3e-14 53.1 0.1 6.6e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 AFI83183.1 - 3.1e-13 49.3 0.2 7.9e-13 48.0 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AFI83183.1 - 1.7e-08 34.7 0.2 5.1e-08 33.2 0.2 1.8 1 0 0 1 1 1 1 PDZ domain DUF2613 PF11021.8 AFI83183.1 - 0.086 13.0 0.3 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Peptidase_M23 PF01551.22 AFI83184.1 - 5e-25 87.5 0.3 1.3e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M23 Spc7 PF08317.11 AFI83184.1 - 0.0033 16.4 12.3 0.0033 16.4 12.3 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Golgin_A5 PF09787.9 AFI83184.1 - 0.0056 16.2 33.7 0.0077 15.7 12.7 2.1 2 0 0 2 2 2 2 Golgin subfamily A member 5 Phage_GPA PF05840.13 AFI83184.1 - 0.22 10.6 8.8 0.33 10.0 8.8 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) SIR2 PF02146.17 AFI83184.1 - 0.72 9.8 3.6 0.83 9.6 1.5 2.1 2 1 0 2 2 2 0 Sir2 family FapA PF03961.13 AFI83184.1 - 1.9 7.0 27.4 0.74 8.3 10.0 2.5 3 0 0 3 3 3 0 Flagellar Assembly Protein A GAS PF13851.6 AFI83184.1 - 2.1 7.7 38.0 0.8 9.0 14.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 AFI83184.1 - 2.5 8.6 28.7 0.13 12.8 3.5 4.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 AFI83184.1 - 3.3 7.8 20.9 0.31 11.1 5.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 AFI83184.1 - 6 7.1 28.9 0.11 12.7 9.1 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 AFI83184.1 - 6.4 7.1 31.6 9.1 6.6 4.4 3.5 1 1 2 3 3 3 0 Tho complex subunit 7 Metalloenzyme PF01676.18 AFI83185.1 - 1e-80 270.7 0.1 1.2e-80 270.5 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AFI83185.1 - 1.8e-79 266.2 0.4 2.5e-79 265.7 0.4 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 AFI83185.1 - 8.7e-07 28.8 0.1 2.1e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 AFI83185.1 - 0.0013 18.8 0.8 0.0084 16.2 0.0 2.5 3 0 0 3 3 3 1 PglZ domain Methyltransf_31 PF13847.6 AFI83185.1 - 0.0022 17.8 0.1 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Melibiase_2 PF16499.5 AFI83185.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A PGM_PMM_II PF02879.16 AFI83185.1 - 0.018 15.7 0.0 0.99 10.1 0.0 2.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HTH_5 PF01022.20 AFI83186.1 - 9.4e-14 51.0 0.3 1.5e-13 50.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AFI83186.1 - 5.7e-12 45.5 0.1 7.7e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AFI83186.1 - 5.4e-07 29.4 0.1 7e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AFI83186.1 - 1.6e-05 24.3 1.4 1.7e-05 24.3 0.1 1.8 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AFI83186.1 - 1.7e-05 24.7 0.3 1.9e-05 24.5 0.3 1.2 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AFI83186.1 - 0.00052 20.1 0.1 0.00072 19.7 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 AFI83186.1 - 0.00089 19.6 0.1 0.0012 19.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_IclR PF09339.10 AFI83186.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 AFI83186.1 - 0.0016 18.3 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_40 PF14493.6 AFI83186.1 - 0.0018 18.7 0.1 0.0021 18.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.27 AFI83186.1 - 0.0062 16.5 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TrmB PF01978.19 AFI83186.1 - 0.0064 16.4 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 AFI83186.1 - 0.01 15.5 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 DprA_WH PF17782.1 AFI83186.1 - 0.011 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain HNF-1_N PF04814.13 AFI83186.1 - 0.011 16.3 0.0 0.014 16.1 0.0 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Sigma70_r4 PF04545.16 AFI83186.1 - 0.012 15.1 0.0 0.032 13.8 0.0 1.7 1 1 1 2 2 2 0 Sigma-70, region 4 Penicillinase_R PF03965.16 AFI83186.1 - 0.042 14.2 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor HTH_28 PF13518.6 AFI83186.1 - 0.098 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AFI83186.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 LexA DNA binding domain HTH_11 PF08279.12 AFI83186.1 - 0.1 12.6 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 HTH domain Rhodanese PF00581.20 AFI83187.1 - 2.3e-18 66.7 0.1 3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Agarase_CBM PF17992.1 AFI83187.1 - 0.09 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Agarase CBM like domain LpxB PF02684.15 AFI83187.1 - 0.14 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Glutaredoxin PF00462.24 AFI83188.1 - 6.4e-26 90.4 0.1 8.4e-26 90.0 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AFI83188.1 - 6.8e-07 29.6 0.0 7.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 AFI83188.1 - 0.00028 20.9 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 AFI83188.1 - 0.00038 20.8 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) SH3BGR PF04908.15 AFI83188.1 - 0.00075 19.6 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Thioredoxin_4 PF13462.6 AFI83188.1 - 0.0015 18.7 1.5 0.77 9.9 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 AFI83188.1 - 0.0021 17.9 0.2 0.0063 16.3 0.2 1.6 1 1 1 2 2 2 1 DSBA-like thioredoxin domain GST_N PF02798.20 AFI83188.1 - 0.01 16.2 0.0 0.013 15.9 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 AFI83188.1 - 0.017 15.6 0.6 0.1 13.0 0.6 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_2 PF13409.6 AFI83188.1 - 0.049 13.9 0.0 0.059 13.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SecB PF02556.14 AFI83189.1 - 3e-54 182.8 0.1 3.6e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB FliW PF02623.15 AFI83189.1 - 0.064 13.2 0.3 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 FliW protein NAD_Gly3P_dh_C PF07479.14 AFI83190.1 - 1.4e-50 171.3 0.4 3.7e-50 169.9 0.5 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 AFI83190.1 - 1.3e-45 155.1 0.0 2e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 AFI83190.1 - 6.8e-10 38.8 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AFI83190.1 - 7.1e-06 26.5 0.0 4.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AFI83190.1 - 7.6e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 AFI83190.1 - 0.00039 20.4 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AFI83190.1 - 0.00053 20.2 0.0 0.024 14.9 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Rossmann-like PF10727.9 AFI83190.1 - 0.00068 19.5 0.2 0.0054 16.6 0.0 2.4 2 1 0 2 2 2 1 Rossmann-like domain Pyr_redox_2 PF07992.14 AFI83190.1 - 0.0031 16.8 0.1 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AFI83190.1 - 0.014 15.6 0.1 0.037 14.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AFI83190.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 AFI83190.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 AFI83190.1 - 0.034 14.7 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AFI83190.1 - 0.053 13.6 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 AFI83190.1 - 0.069 11.8 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pox_A_type_inc PF04508.12 AFI83190.1 - 0.098 12.5 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat XhlA PF10779.9 AFI83191.1 - 0.0087 16.2 4.0 0.015 15.5 4.0 1.4 1 0 0 1 1 1 1 Haemolysin XhlA DUF1664 PF07889.12 AFI83191.1 - 0.015 15.3 0.4 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Methyltransf_28 PF02636.17 AFI83192.1 - 2.9e-50 171.4 0.2 4.3e-50 170.8 0.2 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 AFI83192.1 - 0.009 15.2 0.1 0.97 8.5 0.0 2.4 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FlhD PF05247.13 AFI83192.1 - 0.056 13.7 0.2 2.7 8.3 0.3 2.5 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) adh_short_C2 PF13561.6 AFI83193.1 - 3.1e-29 102.2 0.0 3.5e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AFI83193.1 - 4.8e-25 88.1 0.0 5.8e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 AFI83193.1 - 3.6e-06 26.6 0.1 6.3e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 AFI83193.1 - 1.5e-05 24.6 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 AFI83193.1 - 3.6e-05 23.8 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 AFI83193.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AFI83193.1 - 0.00085 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DHquinase_II PF01220.19 AFI83193.1 - 0.0042 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Dehydroquinase class II GDP_Man_Dehyd PF16363.5 AFI83193.1 - 0.017 14.5 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 AFI83193.1 - 0.18 12.1 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FolB PF02152.18 AFI83194.1 - 3.7e-31 107.9 0.1 4.2e-31 107.8 0.1 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase G3P_acyltransf PF02660.15 AFI83196.1 - 1.5e-50 171.4 12.7 1.8e-50 171.2 12.7 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase Peptidase_U4 PF03419.13 AFI83196.1 - 1.4 8.1 6.5 2.3 7.4 6.5 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2070 PF09843.9 AFI83196.1 - 5 5.3 12.0 5.4 5.2 12.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_M22 PF00814.25 AFI83197.1 - 1e-98 330.4 0.1 1.2e-98 330.2 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AFI83197.1 - 1.2e-05 25.2 0.0 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus Ribosomal_S21 PF01165.20 AFI83198.1 - 5.1e-20 70.9 4.1 5.1e-20 70.9 4.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S21 YqeY PF09424.10 AFI83199.1 - 1e-53 181.3 9.8 1.1e-53 181.1 9.8 1.0 1 0 0 1 1 1 1 Yqey-like protein APP_E2 PF12925.7 AFI83199.1 - 0.058 13.1 0.4 1.6 8.4 0.1 2.1 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein MCR_C PF04609.12 AFI83199.1 - 0.085 11.9 2.1 0.12 11.4 1.7 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C FKBP_N PF01346.18 AFI83199.1 - 1.8 9.6 5.4 8.9 7.3 0.3 2.3 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Toprim_N PF08275.11 AFI83200.1 - 1.9e-44 150.8 0.3 3.6e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AFI83200.1 - 8.9e-40 134.5 0.0 1.7e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 AFI83200.1 - 2.9e-28 99.0 7.5 1.5e-27 96.6 2.6 2.8 3 0 0 3 3 2 1 DNA primase DnaG DnaB-binding Toprim_4 PF13662.6 AFI83200.1 - 3e-18 66.1 0.0 6.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 AFI83200.1 - 4.5e-17 62.2 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 AFI83200.1 - 5.6e-12 45.8 0.0 2.3e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DnaB_bind PF10410.9 AFI83200.1 - 2.4e-10 40.4 0.0 6.9e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 DnaB-helicase binding domain of primase Toprim_3 PF13362.6 AFI83200.1 - 3.1e-07 30.6 0.0 7.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain RasGEF_N_2 PF14663.6 AFI83200.1 - 0.065 13.6 0.1 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain H_kinase_N PF12282.8 AFI83200.1 - 0.09 12.7 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Signal transduction histidine kinase SopE_GEF PF07487.13 AFI83200.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 SopE GEF domain Sigma70_ner PF04546.13 AFI83201.1 - 6.4e-54 182.9 4.8 6.4e-54 182.9 4.8 2.9 3 0 0 3 3 3 1 Sigma-70, non-essential region Sigma70_r3 PF04539.16 AFI83201.1 - 1e-30 105.7 1.0 1e-30 105.7 1.0 4.0 4 0 0 4 4 4 1 Sigma-70 region 3 Sigma70_r1_1 PF03979.14 AFI83201.1 - 2.3e-25 88.4 3.5 2.3e-25 88.4 3.5 3.2 3 0 0 3 3 3 1 Sigma-70 factor, region 1.1 Sigma70_r2 PF04542.14 AFI83201.1 - 7.8e-22 76.8 0.2 1.7e-21 75.7 0.2 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI83201.1 - 4.4e-19 67.7 0.8 4.4e-19 67.7 0.8 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AFI83201.1 - 3.9e-13 49.2 3.3 4.1e-13 49.1 0.4 2.6 3 0 0 3 3 3 1 Sigma-70 factor, region 1.2 FliG_N PF14842.6 AFI83201.1 - 0.019 15.5 3.1 2.1 8.9 0.1 3.7 3 0 0 3 3 3 0 FliG N-terminal domain GAS PF13851.6 AFI83201.1 - 0.063 12.6 2.6 0.18 11.2 2.6 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YL1 PF05764.13 AFI83201.1 - 0.63 10.1 13.6 2.1 8.4 13.6 1.9 1 1 0 1 1 1 0 YL1 nuclear protein DinB_2 PF12867.7 AFI83201.1 - 0.65 10.5 2.1 7.9 7.0 0.1 3.1 3 0 0 3 3 3 0 DinB superfamily Phage_integrase PF00589.22 AFI83202.1 - 6.3e-17 61.9 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AFI83202.1 - 0.0016 18.7 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_3 PF14659.6 AFI83202.1 - 0.023 15.0 0.0 0.058 13.7 0.0 1.8 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Homeodomain PF00046.29 AFI83203.1 - 0.00018 21.3 0.0 0.4 10.6 0.0 2.9 2 1 1 3 3 3 2 Homeodomain HTH_31 PF13560.6 AFI83203.1 - 0.00019 21.7 0.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AFI83203.1 - 0.037 13.9 0.0 23 4.9 0.0 3.2 4 0 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_1 PF01527.20 AFI83203.1 - 0.094 13.0 0.0 25 5.3 0.0 2.6 2 0 0 2 2 2 0 Transposase Terminase_5 PF06056.12 AFI83203.1 - 0.098 12.6 0.1 18 5.3 0.0 2.8 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) Phage_CII PF05269.11 AFI83203.1 - 0.16 12.2 0.1 0.68 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage CII protein MobC PF05713.11 AFI83204.1 - 5.3e-12 46.0 1.8 1.1e-11 45.0 1.8 1.5 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) DASH_Dad3 PF08656.10 AFI83204.1 - 0.014 15.4 1.0 0.02 15.0 0.2 1.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 TraB PF01963.17 AFI83204.1 - 0.1 12.5 0.5 0.098 12.5 0.5 1.1 1 0 0 1 1 1 0 TraB family Relaxase PF03432.14 AFI83205.1 - 3.8e-16 59.4 0.2 4e-14 52.8 0.0 2.9 2 1 1 3 3 3 1 Relaxase/Mobilisation nuclease domain LPD7 PF18821.1 AFI83205.1 - 9.8e-09 35.2 1.2 3e-08 33.7 0.0 2.5 2 1 1 3 3 3 1 Large polyvalent protein-associated domain 7 SSP160 PF06933.11 AFI83205.1 - 0.06 11.5 3.0 0.083 11.1 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA PF00004.29 AFI83207.1 - 1.8e-14 54.3 0.0 1.2e-13 51.7 0.0 2.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI83207.1 - 0.00014 22.3 0.3 0.0042 17.5 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 AFI83207.1 - 0.00055 19.9 0.0 0.002 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 AFI83207.1 - 0.0073 16.2 0.0 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AFI83207.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 AFI83207.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AFI83207.1 - 0.014 15.5 0.0 0.062 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AFI83207.1 - 0.036 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AFI83207.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AFI83207.1 - 0.069 13.5 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AFI83207.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 AFI83207.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AFI83207.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AFI83207.1 - 0.11 12.8 0.1 0.69 10.2 0.0 2.2 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 AFI83207.1 - 0.12 11.7 0.1 0.64 9.4 0.0 2.1 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AFI83207.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 AFI83207.1 - 0.13 12.0 0.1 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 AFI83207.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase LAGLIDADG_1 PF00961.19 AFI83208.1 - 9e-08 33.0 0.1 1.3e-07 32.5 0.1 1.2 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.6 AFI83208.1 - 0.00097 19.4 0.1 0.0016 18.7 0.1 1.3 1 0 0 1 1 1 1 LAGLIDADG-like domain Peptidase_M15_3 PF08291.11 AFI83208.1 - 0.056 13.5 0.1 0.083 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase M15 Endonuc_subdom PF09062.10 AFI83208.1 - 0.074 13.9 0.1 0.11 13.3 0.1 1.4 1 1 0 1 1 1 0 PI-PfuI Endonuclease subdomain HTH_19 PF12844.7 AFI83209.1 - 1.9e-07 31.0 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AFI83209.1 - 3.5e-07 30.5 0.2 4.4e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AFI83209.1 - 1.6e-06 28.0 0.1 2.3e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix DUF1870 PF08965.10 AFI83209.1 - 0.00046 20.2 0.0 0.0005 20.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1870) MqsA_antitoxin PF15731.5 AFI83209.1 - 0.064 13.4 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_25 PF13413.6 AFI83209.1 - 0.16 11.9 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ABC2_membrane_3 PF12698.7 AFI83212.1 - 3.9e-33 115.0 11.2 4.9e-33 114.7 11.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AFI83212.1 - 4.6e-27 94.8 10.7 4.6e-27 94.8 10.7 2.6 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AFI83212.1 - 1.6e-16 60.5 11.3 2.1e-16 60.1 11.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AFI83212.1 - 4e-06 26.9 7.7 4e-06 26.9 7.7 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 AFI83213.1 - 5.5e-58 195.4 0.0 9.6e-28 97.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 AFI83213.1 - 1.7e-39 135.9 6.4 2.3e-39 135.5 6.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 AFI83213.1 - 9e-20 71.7 0.8 2e-05 24.6 0.1 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 AFI83213.1 - 4.5e-17 62.2 17.6 4.7e-17 62.1 14.7 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AFI83213.1 - 2.2e-16 60.0 7.8 3.3e-16 59.4 7.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_15 PF13175.6 AFI83213.1 - 5.4e-05 23.1 0.0 2.5 7.7 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain ABC2_membrane_4 PF12730.7 AFI83213.1 - 0.0001 22.3 10.7 0.0002 21.4 10.7 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 AFI83213.1 - 0.00013 21.6 0.8 0.31 10.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AFI83213.1 - 0.00031 20.7 0.4 0.1 12.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AFI83213.1 - 0.0013 19.2 0.0 0.63 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 AFI83213.1 - 0.0015 18.7 0.0 8.5 6.7 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AFI83213.1 - 0.0065 16.5 0.1 1 9.4 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AFI83213.1 - 0.014 15.7 0.8 5.1 7.4 0.1 3.1 3 1 0 3 3 3 0 AAA domain SMC_N PF02463.19 AFI83213.1 - 0.016 14.7 0.4 13 5.2 0.0 3.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AFI83213.1 - 0.029 14.9 0.4 0.66 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AFI83213.1 - 0.052 14.0 0.1 9.7 6.6 0.0 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AFI83213.1 - 0.052 13.9 0.1 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 AFI83213.1 - 0.055 13.5 0.2 6.8 6.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 AFI83213.1 - 0.07 13.4 1.1 16 5.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain VKG_Carbox PF05090.14 AFI83213.1 - 0.095 11.5 1.2 0.15 10.9 1.2 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase MeaB PF03308.16 AFI83213.1 - 0.11 11.4 0.6 12 4.7 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 AFI83213.1 - 0.13 12.2 0.0 2 8.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 AFI83213.1 - 0.28 10.9 0.3 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain HlyD_D23 PF16576.5 AFI83214.1 - 1e-17 64.1 6.7 4.4e-15 55.5 6.7 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI83214.1 - 7.8e-17 61.9 2.7 9.4e-13 48.8 0.1 3.3 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI83214.1 - 8.4e-08 31.9 0.1 4.7e-07 29.5 0.1 2.3 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AFI83214.1 - 0.00045 20.0 0.0 0.026 14.3 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AFI83214.1 - 0.0019 18.4 0.1 0.033 14.4 0.0 2.9 2 1 1 3 3 3 1 Peptidase family M23 HlyD PF00529.20 AFI83214.1 - 0.0069 16.2 2.2 0.014 15.3 2.2 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HrpB7 PF09486.10 AFI83214.1 - 0.007 16.8 25.3 0.099 13.0 11.9 2.4 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) OEP PF02321.18 AFI83214.1 - 0.0075 16.1 19.2 0.0075 16.1 19.2 1.5 2 0 0 2 2 2 1 Outer membrane efflux protein PTS_EIIA_1 PF00358.20 AFI83214.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Fez1 PF06818.15 AFI83214.1 - 0.074 13.5 5.3 0.13 12.7 5.3 1.3 1 0 0 1 1 1 0 Fez1 KH_2 PF07650.17 AFI83214.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 KH domain BLOC1S3 PF15753.5 AFI83214.1 - 0.13 12.3 3.8 0.46 10.6 0.4 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Inhibitor_I78 PF11720.8 AFI83214.1 - 0.18 11.9 2.1 6 7.0 0.2 3.2 3 0 0 3 3 3 0 Peptidase inhibitor I78 family Tropomyosin PF00261.20 AFI83214.1 - 0.78 9.1 12.5 1.8 7.9 8.2 2.1 2 0 0 2 2 2 0 Tropomyosin Spc7 PF08317.11 AFI83214.1 - 3.1 6.6 9.0 10 4.9 8.6 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein OEP PF02321.18 AFI83215.1 - 3.9e-56 189.8 21.2 3.1e-33 115.2 4.9 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein DUF1707 PF08044.11 AFI83215.1 - 0.00019 21.4 1.1 0.00074 19.5 1.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF348 PF03990.14 AFI83215.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain TetR_N PF00440.23 AFI83216.1 - 1.2e-15 57.1 0.3 2.2e-15 56.2 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AFI83216.1 - 5.3e-08 33.2 0.3 1.8e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AFI83216.1 - 2.7e-07 30.6 0.1 1.1e-06 28.7 0.0 2.0 2 1 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain DUF2887 PF11103.8 AFI83216.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2887) DUF4105 PF13387.6 AFI83218.1 - 1.1e-43 148.9 0.1 1.4e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) Abhydrolase_6 PF12697.7 AFI83219.1 - 5.1e-07 30.5 3.0 5.1e-07 30.5 3.0 2.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.13 AFI83219.1 - 8.5e-06 25.6 0.1 2.7e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 AFI83219.1 - 4e-05 23.2 0.0 9.4e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 AFI83219.1 - 0.0003 20.2 0.0 0.0032 16.8 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 AFI83219.1 - 0.0082 15.7 0.0 0.2 11.2 0.0 2.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 AFI83219.1 - 0.014 15.1 0.3 0.72 9.4 0.1 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 AFI83219.1 - 0.014 15.2 0.0 0.46 10.2 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 AFI83219.1 - 0.02 14.7 0.0 0.085 12.7 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_5 PF12695.7 AFI83219.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AFI83219.1 - 0.087 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 AFI83219.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Palmitoyl protein thioesterase DUF1940 PF09155.10 AFI83222.1 - 0.039 14.1 0.2 0.081 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) TIM PF00121.18 AFI83223.1 - 4.9e-79 265.1 0.0 6.2e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase FBPase PF00316.20 AFI83224.1 - 1.7e-63 213.6 0.0 2.2e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 AFI83224.1 - 0.0077 15.8 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family F_bP_aldolase PF01116.20 AFI83225.1 - 1e-88 297.5 0.0 1.3e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ank_2 PF12796.7 AFI83226.1 - 4.8e-22 78.4 0.7 5.1e-12 46.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 AFI83226.1 - 7.2e-22 77.2 4.1 6.4e-09 35.9 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 AFI83226.1 - 2.8e-19 68.6 3.6 3.3e-06 27.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 AFI83226.1 - 3.4e-19 68.9 0.1 6.5e-09 36.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 AFI83226.1 - 2.3e-16 58.2 0.9 9.8e-05 22.5 0.0 4.1 5 0 0 5 5 5 3 Ankyrin repeat NIT PF08376.10 AFI83226.1 - 0.0089 16.5 1.1 0.0094 16.4 1.1 1.2 1 0 0 1 1 1 1 Nitrate and nitrite sensing Ribosomal_L29 PF00831.23 AFI83226.1 - 2.3 8.2 4.4 0.55 10.2 0.5 2.0 3 0 0 3 3 3 0 Ribosomal L29 protein Pmp3 PF01679.17 AFI83227.1 - 1.1e-19 70.3 8.5 1.2e-19 70.2 8.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Entericidin PF08085.11 AFI83228.1 - 1e-07 31.8 4.5 1.3e-07 31.4 4.5 1.2 1 0 0 1 1 1 1 Entericidin EcnA/B family DUF1356 PF07092.12 AFI83229.1 - 0.053 12.8 0.1 0.055 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) FecR PF04773.13 AFI83230.1 - 1e-05 26.1 0.1 1.4e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 FecR protein POLO_box PF00659.18 AFI83230.1 - 0.035 14.3 0.2 0.059 13.6 0.2 1.4 1 0 0 1 1 1 0 POLO box duplicated region OmpA PF00691.20 AFI83231.1 - 2e-17 63.3 0.1 3.2e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 OmpA family OEP PF02321.18 AFI83232.1 - 1.4e-50 171.7 25.3 1.2e-26 93.7 5.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Amidase02_C PF12123.8 AFI83232.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF2452 PF10504.9 AFI83232.1 - 1.3 8.4 5.1 12 5.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) Redoxin PF08534.10 AFI83233.1 - 4.6e-24 84.8 0.1 5.4e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AFI83233.1 - 1.4e-15 57.3 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.12 AFI83233.1 - 0.026 14.1 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Fer2_2 PF01799.20 AFI83235.1 - 3.3e-27 94.3 0.1 3.3e-27 94.3 0.1 1.5 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2_3 PF13085.6 AFI83235.1 - 1.7e-06 28.0 0.1 2.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AFI83235.1 - 4.3e-06 26.6 1.5 7.2e-06 25.9 0.1 2.0 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Gly_rich_SFCGS PF14272.6 AFI83235.1 - 0.033 14.2 0.2 0.068 13.2 0.1 1.5 1 1 0 1 1 1 0 Glycine-rich SFCGS Ald_Xan_dh_C2 PF02738.18 AFI83236.1 - 1.7e-67 228.2 0.1 2e-32 112.4 0.0 3.0 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AFI83236.1 - 2.7e-07 30.9 0.0 6.2e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain TAT_signal PF10518.9 AFI83236.1 - 0.0045 16.8 0.2 0.0045 16.8 0.2 2.1 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence XdhC_C PF13478.6 AFI83237.1 - 3.9e-37 127.5 0.0 1.2e-36 125.9 0.0 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AFI83237.1 - 1.7e-18 66.6 0.2 2.2e-17 63.0 0.1 2.3 2 0 0 2 2 2 1 XdhC and CoxI family Pyr_redox PF00070.27 AFI83237.1 - 0.019 15.5 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AFI83237.1 - 0.056 12.7 0.0 0.46 9.7 0.0 2.3 1 1 2 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AFI83237.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NTP_transf_3 PF12804.7 AFI83238.1 - 3.4e-28 99.0 0.0 4.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain EcsC PF12787.7 AFI83238.1 - 0.0041 16.8 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 EcsC protein family DUF1328 PF07043.13 AFI83239.1 - 5.2e-14 52.2 19.2 7e-14 51.8 19.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1328) Wzy_C PF04932.15 AFI83239.1 - 0.071 12.7 7.6 0.036 13.7 5.9 1.4 1 1 0 1 1 1 0 O-Antigen ligase DUF2754 PF10953.8 AFI83239.1 - 0.28 11.4 5.2 0.38 11.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Rab5ip PF07019.12 AFI83239.1 - 0.32 11.6 6.9 0.37 11.4 6.9 1.2 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Phage_holin_3_6 PF07332.11 AFI83239.1 - 2.4 8.2 11.5 3.4 7.7 11.5 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4870 PF09685.10 AFI83239.1 - 6.7 6.9 10.2 7.8 6.7 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DUF4969 PF16339.5 AFI83240.1 - 0.056 13.8 0.0 0.063 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) MT0933_antitox PF14013.6 AFI83240.1 - 0.11 12.8 0.9 0.13 12.6 0.9 1.1 1 0 0 1 1 1 0 MT0933-like antitoxin protein Entericidin PF08085.11 AFI83240.1 - 0.78 9.9 6.5 4.8 7.3 0.2 2.5 3 0 0 3 3 3 0 Entericidin EcnA/B family DUF883 PF05957.13 AFI83241.1 - 7.9e-13 48.8 0.6 9.2e-13 48.6 0.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 AFI83241.1 - 1.2e-05 25.3 3.8 1.3e-05 25.1 3.8 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain KxDL PF10241.9 AFI83241.1 - 0.0028 17.9 2.2 0.0073 16.6 0.6 2.0 1 1 0 2 2 2 1 Uncharacterized conserved protein GOLGA2L5 PF15070.6 AFI83241.1 - 0.0038 16.0 1.0 0.0039 15.9 1.0 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 HBM PF16591.5 AFI83241.1 - 0.0073 15.8 1.5 0.0082 15.6 1.5 1.1 1 0 0 1 1 1 1 Helical bimodular sensor domain YtxH PF12732.7 AFI83241.1 - 0.009 16.5 4.8 0.016 15.7 1.2 2.1 1 1 0 1 1 1 1 YtxH-like protein IFT57 PF10498.9 AFI83241.1 - 0.022 13.8 2.8 0.023 13.7 2.8 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FlxA PF14282.6 AFI83241.1 - 0.026 14.5 3.3 0.033 14.2 3.3 1.2 1 0 0 1 1 1 0 FlxA-like protein EzrA PF06160.12 AFI83241.1 - 0.053 11.7 1.4 0.064 11.4 1.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rootletin PF15035.6 AFI83241.1 - 0.064 13.3 3.0 0.089 12.8 2.8 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cep57_MT_bd PF06657.13 AFI83241.1 - 0.065 13.7 0.7 0.096 13.1 0.7 1.3 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Lectin_N PF03954.14 AFI83241.1 - 0.066 13.0 0.8 0.079 12.7 0.8 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 AFI83241.1 - 0.08 13.1 1.9 0.098 12.8 1.9 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 AFI83241.1 - 0.083 11.8 2.3 0.09 11.6 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MT PF12777.7 AFI83241.1 - 0.094 11.7 0.9 0.097 11.7 0.9 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Enkurin PF13864.6 AFI83241.1 - 0.095 13.1 1.6 0.15 12.5 1.5 1.4 1 1 0 1 1 1 0 Calmodulin-binding Uso1_p115_C PF04871.13 AFI83241.1 - 0.1 13.0 3.9 0.13 12.6 3.9 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PRKG1_interact PF15898.5 AFI83241.1 - 0.11 13.4 2.2 0.14 13.1 2.2 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 AFI83241.1 - 0.11 12.5 5.0 0.14 12.2 5.0 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 AFI83241.1 - 0.11 12.6 0.3 0.11 12.6 0.3 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DASH_Hsk3 PF08227.11 AFI83241.1 - 0.13 12.7 1.3 2.9 8.3 0.2 2.3 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like CsoSCA PF08936.10 AFI83241.1 - 0.13 10.9 1.0 0.14 10.8 1.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase EIIA-man PF03610.16 AFI83241.1 - 0.13 12.5 0.3 0.18 12.0 0.2 1.3 1 1 0 1 1 1 0 PTS system fructose IIA component ApoO PF09769.9 AFI83241.1 - 0.13 12.2 0.6 0.2 11.6 0.6 1.4 1 1 0 1 1 1 0 Apolipoprotein O DUF4854 PF16146.5 AFI83241.1 - 0.16 12.3 2.7 5.6 7.4 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4854) Swi5 PF07061.11 AFI83241.1 - 0.25 11.4 2.5 0.41 10.7 2.5 1.5 1 1 0 1 1 1 0 Swi5 DUF1043 PF06295.12 AFI83241.1 - 1.2 9.2 6.9 0.35 10.9 1.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) Phage_holin_3_6 PF07332.11 AFI83242.1 - 1.4e-05 25.1 2.5 1.4e-05 25.1 2.5 1.5 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III MARVEL PF01284.23 AFI83242.1 - 0.056 13.5 4.4 0.092 12.8 4.4 1.3 1 0 0 1 1 1 0 Membrane-associating domain CPBP PF02517.16 AFI83242.1 - 0.19 12.1 5.6 22 5.5 5.6 2.5 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease CbtB PF09489.10 AFI83242.1 - 2.6 8.2 11.1 0.21 11.7 2.0 2.9 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF202 PF02656.15 AFI83242.1 - 6.6 7.3 9.5 3.6 8.1 6.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Syndecan PF01034.20 AFI83242.1 - 8.2 6.4 9.4 0.94 9.4 1.0 2.8 2 2 2 4 4 4 0 Syndecan domain Sigma70_r4 PF04545.16 AFI83243.1 - 0.00038 19.9 0.4 0.00074 19.0 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 GcrA PF07750.11 AFI83243.1 - 0.003 18.0 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 GcrA cell cycle regulator Phage_antitermQ PF06530.12 AFI83243.1 - 0.047 13.6 0.1 0.14 12.1 0.0 1.8 1 1 1 2 2 2 0 Phage antitermination protein Q YjfB_motility PF14070.6 AFI83244.1 - 1.5e-05 25.1 8.8 1.7e-05 24.8 8.8 1.1 1 0 0 1 1 1 1 Putative motility protein Phage_TAC_3 PF06896.11 AFI83244.1 - 0.049 14.2 0.2 0.056 14.0 0.2 1.1 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC SSF PF00474.17 AFI83245.1 - 3.3e-36 125.0 29.5 4.4e-36 124.6 29.0 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family MitoNEET_N PF10660.9 AFI83245.1 - 0.021 14.8 1.5 0.085 12.9 0.1 2.7 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus OEP PF02321.18 AFI83248.1 - 8.1e-31 107.3 38.2 6.2e-20 71.8 13.0 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein DUF2730 PF10805.8 AFI83248.1 - 0.41 10.8 6.3 7.5 6.7 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) HlyD_D23 PF16576.5 AFI83249.1 - 7.5e-26 90.7 0.1 2.1e-16 59.8 0.0 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI83249.1 - 1.3e-13 51.5 0.0 9.5e-09 35.9 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI83249.1 - 7.4e-06 25.7 0.2 2.4e-05 24.1 0.1 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AFI83249.1 - 8.1e-06 25.6 0.0 2.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme NQRA PF05896.11 AFI83249.1 - 0.00064 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 AFI83249.1 - 0.0038 17.2 0.1 0.012 15.5 0.1 1.8 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.20 AFI83249.1 - 0.0048 16.7 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS YqfD PF06898.11 AFI83249.1 - 0.025 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Lipocalin_7 PF14651.6 AFI83249.1 - 0.032 14.2 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family ATP-synt_ab_Xtn PF16886.5 AFI83249.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension Peptidase_M23 PF01551.22 AFI83249.1 - 0.13 12.5 0.5 1.1 9.6 0.2 2.6 2 1 1 3 3 3 0 Peptidase family M23 ACR_tran PF00873.19 AFI83250.1 - 0 1029.7 18.9 0 1029.5 18.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI83250.1 - 0.21 10.5 42.3 0.13 11.1 14.8 3.4 2 1 0 2 2 2 0 MMPL family DUF4168 PF13767.6 AFI83251.1 - 1.6e-17 64.4 4.0 2.6e-17 63.8 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4168) NOG1_N PF17835.1 AFI83251.1 - 0.00054 20.0 0.0 0.00068 19.6 0.0 1.2 1 0 0 1 1 1 1 NOG1 N-terminal helical domain DUF2574 PF10836.8 AFI83251.1 - 0.12 12.3 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) PepSY_2 PF13670.6 AFI83251.1 - 0.77 9.8 6.5 0.25 11.4 0.6 2.5 2 1 1 3 3 3 0 Peptidase propeptide and YPEB domain HATPase_c PF02518.26 AFI83252.1 - 7.3e-19 68.3 0.0 2.5e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI83252.1 - 3.7e-11 42.9 5.1 4.8e-11 42.5 0.6 3.3 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AFI83252.1 - 1.3e-09 38.3 0.4 1.3e-09 38.3 0.4 3.3 4 0 0 4 4 4 1 HAMP domain HATPase_c_2 PF13581.6 AFI83252.1 - 1.2e-08 34.9 0.0 3.4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain dCache_1 PF02743.18 AFI83252.1 - 1.4e-06 28.3 0.6 3.5e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 Cache domain HATPase_c_5 PF14501.6 AFI83252.1 - 2e-06 27.6 0.0 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 1 GHKL domain CHASE8 PF17152.4 AFI83252.1 - 7.9e-05 22.8 0.5 0.0025 18.1 0.0 2.4 2 0 0 2 2 2 1 Periplasmic sensor domain sCache_3_2 PF17203.4 AFI83252.1 - 0.0051 17.0 0.0 0.0051 17.0 0.0 2.8 4 1 1 5 5 5 1 Single cache domain 3 dCache_3 PF14827.6 AFI83252.1 - 0.013 15.2 0.2 0.047 13.3 0.2 1.9 1 1 0 1 1 1 0 Double sensory domain of two-component sensor kinase sCache_3_3 PF17202.4 AFI83252.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Single cache domain 3 HATPase_c_3 PF13589.6 AFI83252.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AFI83252.1 - 0.055 13.7 0.1 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 PAS fold Sigma54_activat PF00158.26 AFI83253.1 - 1.2e-66 223.5 0.1 1.7e-66 223.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AFI83253.1 - 7.7e-27 94.1 0.1 1.2e-25 90.2 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 AFI83253.1 - 2.2e-20 72.9 0.0 4.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AFI83253.1 - 1.6e-09 37.4 0.8 5.2e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA PF00004.29 AFI83253.1 - 4e-06 27.3 0.1 0.0001 22.7 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) HTH_23 PF13384.6 AFI83253.1 - 0.00014 21.5 0.0 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain AAA_5 PF07728.14 AFI83253.1 - 0.00018 21.6 0.0 0.00045 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_28 PF13518.6 AFI83253.1 - 0.00024 21.2 0.1 0.00079 19.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AFI83253.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix Mg_chelatase PF01078.21 AFI83253.1 - 0.0026 17.2 0.3 0.72 9.2 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI HTH_17 PF12728.7 AFI83253.1 - 0.0048 17.0 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 AFI83253.1 - 0.0061 17.0 2.4 0.0074 16.7 0.6 2.4 2 1 0 2 2 2 1 AAA ATPase domain HTH_Tnp_1_2 PF13022.6 AFI83253.1 - 0.0094 16.1 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HGD-D PF06050.13 AFI83253.1 - 0.019 14.8 0.0 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component WG_beta_rep PF14903.6 AFI83254.1 - 8.7e-92 300.9 21.1 4e-12 46.2 0.0 9.8 5 2 5 10 10 10 9 WG containing repeat DUF4380 PF14315.6 AFI83254.1 - 0.025 13.5 0.0 5.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4380) Retrotran_gag_3 PF14244.6 AFI83254.1 - 0.028 14.2 0.1 6.5 6.6 0.0 4.0 4 0 0 4 4 4 0 gag-polypeptide of LTR copia-type LLC1 PF14945.6 AFI83254.1 - 0.031 14.8 0.4 46 4.6 0.0 3.9 2 1 3 5 5 5 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF3761 PF12587.8 AFI83254.1 - 0.062 13.7 0.0 88 3.6 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3761) EAGR_box PF16713.5 AFI83254.1 - 1.3 8.8 13.2 9.4 6.0 0.3 5.4 6 0 0 6 6 6 0 Enriched in aromatic and glycine Residues box Pyr_redox_2 PF07992.14 AFI83255.1 - 1.9e-68 230.8 0.5 2.4e-68 230.5 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AFI83255.1 - 2.3e-34 118.0 0.3 4.9e-34 116.9 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AFI83255.1 - 4e-22 78.6 1.8 6.4e-20 71.5 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AFI83255.1 - 4e-16 59.2 0.4 9.7e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AFI83255.1 - 2.3e-08 33.2 1.3 0.00065 18.5 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 AFI83255.1 - 4.1e-06 26.4 0.1 0.0001 21.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AFI83255.1 - 1.9e-05 24.0 0.0 0.073 12.2 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AFI83255.1 - 4.1e-05 23.3 6.4 0.0011 18.6 0.0 3.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AFI83255.1 - 9.4e-05 21.9 0.0 0.00033 20.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AFI83255.1 - 0.00065 19.7 0.8 0.0016 18.5 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AFI83255.1 - 0.00074 18.9 1.6 0.062 12.6 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AFI83255.1 - 0.0009 18.4 5.6 0.0078 15.3 3.1 3.0 2 2 0 2 2 2 1 Glucose inhibited division protein A XdhC_C PF13478.6 AFI83255.1 - 0.03 14.8 0.1 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Thi4 PF01946.17 AFI83255.1 - 0.061 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 AFI83255.1 - 0.089 11.8 1.5 0.27 10.3 1.1 2.0 2 0 0 2 2 2 0 FAD binding domain DUF4988 PF16378.5 AFI83255.1 - 0.09 12.4 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function FAD_binding_3 PF01494.19 AFI83255.1 - 0.091 12.0 0.2 12 5.0 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 AFI83255.1 - 0.34 10.3 1.6 13 5.1 0.1 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AFI83255.1 - 0.39 10.6 2.2 21 4.9 0.2 3.1 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Redoxin PF08534.10 AFI83256.1 - 6.4e-26 90.8 0.0 7.8e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AFI83256.1 - 5.3e-10 39.3 0.0 6.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family EAL PF00563.20 AFI83257.1 - 1.9e-65 220.7 1.3 4.9e-65 219.4 1.3 1.8 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI83257.1 - 5.3e-38 130.3 1.3 1.4e-37 128.9 1.3 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AFI83257.1 - 9.4e-09 35.4 0.0 3.7e-08 33.5 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 AFI83257.1 - 7.8e-07 29.8 0.0 2.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AFI83257.1 - 1.8e-06 28.3 0.0 3.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AFI83257.1 - 0.0023 18.3 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain LDcluster4 PF18306.1 AFI83257.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 SLOG cluster4 family PAS_3 PF08447.12 AFI83258.1 - 5.6e-25 87.5 1.9 1.5e-17 63.6 0.3 3.4 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AFI83258.1 - 3.6e-24 85.0 0.0 1.6e-12 47.5 0.0 3.8 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 AFI83258.1 - 6.7e-23 80.9 0.1 2.9e-08 33.7 0.0 4.4 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 AFI83258.1 - 2.9e-21 75.8 0.6 2.1e-05 24.7 0.0 4.4 4 0 0 4 4 4 3 PAS fold HATPase_c PF02518.26 AFI83258.1 - 2e-19 70.1 0.0 3.9e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AFI83258.1 - 5e-18 65.3 0.0 1.2e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AFI83258.1 - 4.3e-09 36.2 0.0 1.6e-05 24.8 0.0 4.0 4 0 0 4 4 4 1 PAS domain HisKA PF00512.25 AFI83258.1 - 1.1e-07 31.8 1.0 3.7e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HPTransfase PF10090.9 AFI83258.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Ldh_1_N PF00056.23 AFI83258.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 5-FTHF_cyc-lig PF01812.20 AFI83259.1 - 6.7e-23 81.5 0.0 7.7e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rrf2 PF02082.20 AFI83260.1 - 2e-20 72.9 0.1 2.9e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_IclR PF09339.10 AFI83260.1 - 0.0077 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 AFI83260.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 AFI83260.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain NAD_binding_1 PF00175.21 AFI83261.1 - 4.4e-16 59.5 0.0 9.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AFI83261.1 - 1.6e-11 44.5 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 AFI83261.1 - 2.5e-09 37.6 0.3 2.5e-09 37.6 0.3 2.0 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 AFI83261.1 - 0.00012 22.2 0.0 0.0011 19.2 0.0 2.1 1 1 0 2 2 2 1 Ferric reductase NAD binding domain PepSY PF03413.19 AFI83262.1 - 4.1e-12 46.5 1.4 5.5e-12 46.1 1.4 1.2 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AFI83262.1 - 2e-07 30.9 1.5 3.6e-07 30.1 1.5 1.4 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain GhoS PF11080.8 AFI83262.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease GhoS HATPase_c PF02518.26 AFI83263.1 - 2.5e-13 50.5 0.0 5.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI83263.1 - 6.1e-06 26.1 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AFI83263.1 - 0.00065 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain FlgN PF05130.12 AFI83263.1 - 0.01 16.3 8.1 0.028 14.9 8.1 1.7 1 0 0 1 1 1 0 FlgN protein HATPase_c_3 PF13589.6 AFI83263.1 - 0.04 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PilJ PF13675.6 AFI83263.1 - 0.11 12.6 4.3 1.6 8.8 0.6 3.1 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3159 PF11361.8 AFI83263.1 - 0.12 12.1 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3159) HAMP PF00672.25 AFI83263.1 - 0.18 12.2 0.3 0.18 12.2 0.3 2.4 3 0 0 3 3 3 0 HAMP domain DASH_Spc19 PF08287.11 AFI83263.1 - 0.2 11.6 6.9 0.47 10.3 6.9 1.7 1 0 0 1 1 1 0 Spc19 Uso1_p115_C PF04871.13 AFI83263.1 - 0.21 12.0 3.3 0.33 11.3 0.6 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4795 PF16043.5 AFI83263.1 - 0.26 10.8 3.1 0.48 10.0 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CLZ PF16526.5 AFI83263.1 - 0.53 10.7 5.7 0.32 11.4 1.2 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GlutR_dimer PF00745.20 AFI83263.1 - 1 9.9 6.3 8.9 6.8 0.6 2.5 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Response_reg PF00072.24 AFI83264.1 - 5e-23 81.4 0.0 6.7e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI83264.1 - 1.8e-22 79.2 0.1 3.6e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal PepSY PF03413.19 AFI83265.1 - 8.6e-11 42.2 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AFI83265.1 - 6.5e-05 22.9 0.0 7.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DUF5643 PF18705.1 AFI83265.1 - 0.075 13.0 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Sperm_Ag_HE2 PF05324.13 AFI83265.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Sperm antigen HE2 CMAS PF02353.20 AFI83266.1 - 9.9e-91 303.8 1.0 9.9e-91 303.8 1.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 AFI83266.1 - 9.2e-15 54.9 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI83266.1 - 1.6e-14 54.3 0.0 7.6e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83266.1 - 3.9e-14 53.1 0.0 1.4e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83266.1 - 4e-10 40.3 0.0 1.2e-09 38.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83266.1 - 1.7e-08 34.4 0.0 4e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AFI83266.1 - 0.00097 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 AFI83266.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 AFI83266.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 AFI83266.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-P11 PF03854.14 AFI83266.1 - 0.086 12.5 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 P-11 zinc finger DUF938 PF06080.12 AFI83266.1 - 0.089 12.5 0.0 0.5 10.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 AFI83266.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 AFI83266.1 - 0.17 11.8 0.1 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Catalase PF00199.19 AFI83267.1 - 1.5e-190 633.2 1.2 2e-190 632.8 1.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AFI83267.1 - 3.2e-21 75.3 0.1 6.3e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ferritin PF00210.24 AFI83268.1 - 1e-27 96.8 0.7 1.2e-27 96.6 0.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain Aldedh PF00171.22 AFI83269.1 - 1.2e-127 426.2 0.2 1.5e-127 426.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPP_enzyme_N PF02776.18 AFI83270.1 - 3.8e-54 182.9 0.0 1.2e-53 181.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AFI83270.1 - 2.1e-38 131.5 0.0 3.6e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AFI83270.1 - 9.7e-34 116.0 0.0 6.9e-33 113.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 AFI83270.1 - 0.0049 16.1 0.1 0.0093 15.2 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Peptidase_M55 PF04951.13 AFI83270.1 - 0.022 14.1 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 D-aminopeptidase CO_dh PF02552.16 AFI83270.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF498 PF04430.14 AFI83270.1 - 0.09 12.9 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) OmpA PF00691.20 AFI83271.1 - 1.1e-15 57.7 0.1 1.1e-14 54.6 0.0 2.1 2 0 0 2 2 2 1 OmpA family MotB_plug PF13677.6 AFI83271.1 - 9.4e-14 50.7 1.6 1.9e-13 49.7 1.6 1.5 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB ExbD PF02472.16 AFI83271.1 - 1.1 9.4 8.2 5.9 7.1 8.2 2.0 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR EAL PF00563.20 AFI83273.1 - 8.8e-65 218.5 0.6 1.4e-64 217.8 0.6 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI83273.1 - 1.3e-48 164.8 0.3 3.8e-48 163.3 0.0 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain CHASE PF03924.13 AFI83273.1 - 2.3e-20 73.3 0.0 4.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 CHASE domain PAS PF00989.25 AFI83273.1 - 1.6e-19 70.0 0.1 6.5e-11 42.2 0.0 4.0 3 1 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AFI83273.1 - 4.9e-18 65.3 0.0 6.9e-11 42.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AFI83273.1 - 6.4e-17 61.2 0.0 5.7e-07 29.4 0.0 3.6 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 AFI83273.1 - 7.2e-13 48.8 0.0 5.5e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AFI83273.1 - 2.9e-09 37.1 0.2 2.9e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold DUF2653 PF10850.8 AFI83273.1 - 0.057 13.6 0.1 0.26 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) PAS_12 PF18095.1 AFI83273.1 - 0.059 13.0 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain SNF PF00209.18 AFI83274.1 - 2.9e-49 168.2 40.5 6.5e-26 91.1 7.5 2.1 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family SNARE_assoc PF09335.11 AFI83276.1 - 2.2e-22 79.8 7.8 4.5e-22 78.8 7.8 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PLDc_2 PF13091.6 AFI83276.1 - 6.2e-15 55.3 0.0 1.7e-11 44.2 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 AFI83276.1 - 9.8e-11 41.4 2.1 0.00027 21.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF2529 PF10740.9 AFI83276.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) RseC_MucC PF04246.12 AFI83276.1 - 4.6 7.2 9.6 0.43 10.5 2.1 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Exo_endo_phos PF03372.23 AFI83277.1 - 7e-11 42.1 0.0 9.2e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF748 PF05359.11 AFI83279.1 - 3.3e-72 241.6 10.0 4e-31 108.3 0.0 4.8 5 1 1 6 6 6 3 Domain of Unknown Function (DUF748) T2SSN PF01203.19 AFI83279.1 - 0.32 11.2 3.3 2.7 8.1 0.0 3.6 4 1 0 4 4 4 0 Type II secretion system (T2SS), protein N AAA_5 PF07728.14 AFI83282.1 - 1.5e-34 118.9 0.0 2.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 AFI83282.1 - 2e-28 98.5 0.1 3.8e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Mg_chelatase PF01078.21 AFI83282.1 - 6.9e-06 25.6 0.0 0.0081 15.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AFI83282.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI83282.1 - 0.00023 21.6 0.0 0.00033 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AFI83282.1 - 0.00035 21.0 0.0 0.00059 20.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 AFI83282.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 AFI83282.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_6 PF12774.7 AFI83282.1 - 0.0024 16.9 0.0 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 AFI83282.1 - 0.0026 17.8 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 AFI83282.1 - 0.0029 17.9 0.0 0.0077 16.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 AFI83282.1 - 0.0077 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.6 AFI83282.1 - 0.0081 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 AFI83282.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain RuvB_N PF05496.12 AFI83282.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 AFI83282.1 - 0.019 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 AFI83282.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AFI83282.1 - 0.026 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AFI83282.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 AFI83282.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 AFI83282.1 - 0.052 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AFI83282.1 - 0.095 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 AFI83282.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) VWA PF00092.28 AFI83283.1 - 3.7e-07 30.6 0.0 6.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AFI83283.1 - 2e-05 25.2 0.0 4.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AFI83283.1 - 0.013 14.9 0.0 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VGCC_alpha2 PF08473.11 AFI83283.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd COX1 PF00115.20 AFI83284.1 - 7.9e-77 258.9 55.4 1.1e-76 258.5 55.4 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_C PF00034.21 AFI83285.1 - 6.1e-10 40.1 0.0 8.5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AFI83285.1 - 1.1e-05 25.7 0.1 2e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 AFI83285.1 - 0.09 12.5 0.0 8.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c-550 domain MCR PF18509.1 AFI83285.1 - 0.59 9.8 2.8 0.46 10.1 0.5 1.9 2 0 0 2 2 2 0 Magnetochrome domain Sigma54_activat PF00158.26 AFI83286.1 - 1.3e-68 230.0 0.0 2.1e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AFI83286.1 - 3.2e-23 82.4 0.0 7.1e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AFI83286.1 - 1.2e-08 35.0 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AFI83286.1 - 2.5e-06 28.0 0.0 6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GAF PF01590.26 AFI83286.1 - 2.7e-06 28.0 0.0 5.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain HTH_8 PF02954.19 AFI83286.1 - 1.2e-05 25.0 0.0 4.2e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AFI83286.1 - 6.4e-05 22.4 0.0 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI GAF_2 PF13185.6 AFI83286.1 - 0.00026 21.3 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain AAA_2 PF07724.14 AFI83286.1 - 0.00056 20.1 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) GAF_3 PF13492.6 AFI83286.1 - 0.0016 18.8 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 GAF domain AAA_16 PF13191.6 AFI83286.1 - 0.0024 18.3 0.2 0.0084 16.5 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AFI83286.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AFI83286.1 - 0.015 15.6 0.1 0.06 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_tran_WecB PF03808.13 AFI83286.1 - 0.046 13.7 0.2 0.11 12.5 0.1 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family AAA_7 PF12775.7 AFI83286.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 AFI83286.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Methyltransf_10 PF05971.12 AFI83286.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase COX3 PF00510.18 AFI83287.1 - 1.2e-10 41.7 20.8 2.6e-10 40.6 20.8 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III DUF4271 PF14093.6 AFI83287.1 - 0.011 15.7 10.8 0.011 15.7 10.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) MTABC_N PF16185.5 AFI83287.1 - 0.097 12.2 8.7 0.13 11.8 7.7 1.6 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region MARVEL PF01284.23 AFI83287.1 - 7.7 6.5 16.3 0.039 14.0 3.9 2.4 2 1 0 2 2 2 0 Membrane-associating domain COX4_pro PF03626.14 AFI83288.1 - 3.4e-07 30.6 9.6 4.5e-07 30.2 9.6 1.1 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV NnrS PF05940.12 AFI83289.1 - 1.3e-71 242.0 54.8 1.5e-71 241.8 54.8 1.0 1 0 0 1 1 1 1 NnrS protein ISK_Channel PF02060.15 AFI83289.1 - 2 8.1 4.0 0.97 9.2 1.0 2.0 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Mob_synth_C PF06463.13 AFI83290.1 - 9.9e-35 119.3 0.0 1.5e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AFI83290.1 - 5.2e-30 105.0 0.0 7.2e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AFI83290.1 - 1.1e-09 38.6 0.0 3e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AFI83290.1 - 1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain DGC PF08859.11 AFI83291.1 - 2.5e-19 69.3 0.2 3e-19 69.1 0.2 1.1 1 0 0 1 1 1 1 DGC domain PilJ PF13675.6 AFI83292.1 - 2.1e-23 82.5 3.0 9.4e-22 77.2 0.0 3.3 3 0 0 3 3 3 1 Type IV pili methyl-accepting chemotaxis transducer N-term HisKA_3 PF07730.13 AFI83292.1 - 5.5e-16 58.9 4.0 1.4e-15 57.6 1.9 2.7 3 0 0 3 3 3 1 Histidine kinase HAMP PF00672.25 AFI83292.1 - 4.3e-13 49.4 0.0 1.2e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 HAMP domain GAF_2 PF13185.6 AFI83292.1 - 1.3e-11 45.0 0.0 2.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AFI83292.1 - 1.2e-09 38.6 0.0 2.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 AFI83292.1 - 5.6e-08 33.3 0.7 1.6e-07 31.8 0.7 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 AFI83292.1 - 3.8e-07 30.8 0.0 8.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 AFI83292.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain UL42 PF17638.2 AFI83292.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 HCMV UL42 Response_reg PF00072.24 AFI83293.1 - 2.9e-28 98.3 0.1 1.4e-27 96.1 0.0 2.0 1 1 1 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AFI83293.1 - 1.2e-20 72.7 0.4 2.2e-20 71.9 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI83293.1 - 8.1e-09 35.0 0.1 1.7e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AFI83293.1 - 7.4e-05 22.2 0.1 0.00018 21.0 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AFI83293.1 - 0.0006 19.5 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI83293.1 - 0.00085 19.1 0.0 0.003 17.3 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_40 PF14493.6 AFI83293.1 - 0.03 14.8 0.1 0.13 12.7 0.1 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 AFI83293.1 - 0.054 13.4 0.1 0.098 12.5 0.1 1.5 1 1 0 1 1 1 0 ECF sigma factor HTH_24 PF13412.6 AFI83293.1 - 0.055 13.0 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 AFI83295.1 - 1.6e-41 142.4 70.0 4.3e-41 141.0 48.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4525 PF15027.6 AFI83295.1 - 0.13 12.0 0.4 0.59 9.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) MFS_1 PF07690.16 AFI83296.1 - 4.2e-12 45.7 67.0 2.4e-10 39.9 10.1 3.8 2 1 2 4 4 4 3 Major Facilitator Superfamily Molybdopterin PF00384.22 AFI83297.1 - 1e-136 456.4 0.3 1.6e-136 455.8 0.3 1.3 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI83297.1 - 1.8e-20 73.0 0.1 4.6e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Nitr_red_alph_N PF14710.6 AFI83297.1 - 1.6e-18 66.9 2.1 3.9e-18 65.6 2.1 1.7 1 0 0 1 1 1 1 Respiratory nitrate reductase alpha N-terminal Molybdop_Fe4S4 PF04879.16 AFI83297.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Fe4S4 domain Fer4_11 PF13247.6 AFI83298.1 - 1.3e-36 124.7 7.5 3.2e-36 123.5 7.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 AFI83298.1 - 4.8e-26 90.3 0.0 8e-26 89.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_6 PF12837.7 AFI83298.1 - 1e-07 31.7 21.2 0.0012 18.9 0.2 4.5 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_10 PF13237.6 AFI83298.1 - 1.1e-07 31.8 18.1 1.1e-05 25.4 5.2 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI83298.1 - 1.4e-07 32.0 18.1 0.00016 22.2 6.4 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI83298.1 - 1.3e-06 28.2 23.9 0.0031 17.5 1.7 4.6 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 AFI83298.1 - 1.9e-05 24.7 18.2 0.0044 17.2 5.3 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AFI83298.1 - 2.5e-05 24.9 3.6 0.04 14.6 0.7 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4 PF00037.27 AFI83298.1 - 0.00017 21.2 18.3 0.0065 16.2 1.7 4.7 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_4 PF12800.7 AFI83298.1 - 0.0046 17.4 29.0 0.024 15.1 1.3 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AFI83298.1 - 0.021 15.0 22.9 0.042 14.0 4.0 3.5 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AFI83298.1 - 0.083 13.4 0.1 0.083 13.4 0.1 3.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 AFI83298.1 - 0.15 12.6 18.6 1.1 9.9 0.1 4.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI83298.1 - 0.21 12.1 0.1 0.21 12.1 0.1 4.0 2 1 1 3 3 2 0 4Fe-4S dicluster domain Nitrate_red_del PF02613.15 AFI83299.1 - 2.3e-12 47.1 1.1 2.9e-12 46.8 1.1 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit Nitrate_red_gam PF02665.14 AFI83300.1 - 2.8e-85 285.3 9.8 3.2e-85 285.1 9.8 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF4014 PF13198.6 AFI83300.1 - 1.9 8.9 6.6 5.2 7.5 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) Pro_CA PF00484.19 AFI83301.1 - 1.7e-48 164.8 0.0 2e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PqqD PF05402.12 AFI83303.1 - 1.7e-11 44.3 0.0 2.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) N_Asn_amidohyd PF14736.6 AFI83303.1 - 0.0041 16.3 0.0 0.005 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Radical_SAM PF04055.21 AFI83304.1 - 3.8e-22 79.4 0.0 5.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AFI83304.1 - 1.7e-09 38.0 0.3 3.9e-09 36.9 0.3 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AFI83304.1 - 2.5e-06 27.8 0.0 7.5e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AFI83304.1 - 1.5e-05 25.1 0.6 3.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain NmrA PF05368.13 AFI83304.1 - 0.068 12.7 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Urate_ox_N PF06181.11 AFI83305.1 - 3.3e-07 29.9 0.1 3.6e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Urate oxidase N-terminal Aminotran_5 PF00266.19 AFI83306.1 - 2.1e-51 175.1 0.0 2.4e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DHO_dh PF01180.21 AFI83307.1 - 1.4e-24 86.8 0.0 2e-08 33.8 0.0 3.0 2 1 1 3 3 3 3 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AFI83307.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein FMN_dh PF01070.18 AFI83307.1 - 0.0045 16.1 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AFI83307.1 - 0.035 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain QRPTase_C PF01729.19 AFI83307.1 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.17 AFI83307.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase NMO PF03060.15 AFI83307.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4096 PF13340.6 AFI83308.1 - 6.9e-26 90.3 3.0 1.2e-25 89.5 1.4 2.2 3 0 0 3 3 3 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 AFI83308.1 - 1.2e-17 64.3 5.4 1.6e-16 60.6 3.2 2.4 2 1 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI83308.1 - 2.1e-16 60.1 0.2 4.2e-16 59.1 0.2 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AFI83308.1 - 3.1e-08 33.8 0.0 5.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI83308.1 - 2.1e-06 27.5 0.1 5e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Fer4_5 PF12801.7 AFI83309.1 - 1.1e-21 76.5 10.5 1.3e-14 53.8 4.5 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain FMN_bind PF04205.14 AFI83309.1 - 7.5e-08 32.8 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 FMN-binding domain DUF3995 PF13160.6 AFI83309.1 - 0.076 13.4 4.5 0.13 12.7 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) GASA PF02704.14 AFI83309.1 - 0.16 12.1 10.8 0.28 11.4 10.8 1.3 1 0 0 1 1 1 0 Gibberellin regulated protein Fer4 PF00037.27 AFI83309.1 - 4.8 7.2 6.5 20 5.2 0.9 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain NosD PF05048.13 AFI83310.1 - 6.8e-67 225.2 27.3 9.4e-64 215.0 27.3 2.1 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 AFI83310.1 - 3.7e-29 101.6 43.1 1.6e-20 73.5 12.2 3.0 1 1 2 3 3 3 3 Right handed beta helix region ABC_tran PF00005.27 AFI83311.1 - 4.4e-30 105.0 0.0 7.8e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI83311.1 - 1.2e-11 45.0 0.4 3.4e-07 30.4 0.0 2.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AFI83311.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AFI83311.1 - 0.017 15.6 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AFI83311.1 - 0.049 13.9 0.5 0.32 11.3 0.4 2.3 1 1 0 1 1 1 0 AAA domain DUF4162 PF13732.6 AFI83311.1 - 0.061 14.1 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Thymidylate_kin PF02223.17 AFI83311.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 AFI83311.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AFI83311.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MukB PF04310.12 AFI83311.1 - 0.14 12.0 0.1 0.42 10.4 0.1 1.9 1 1 0 1 1 1 0 MukB N-terminal AAA_24 PF13479.6 AFI83311.1 - 0.18 11.5 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 AFI83312.1 - 2.6e-40 138.5 23.3 3.8e-40 138.0 23.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AFI83312.1 - 5.3e-09 36.3 14.6 5.3e-09 36.3 14.6 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AFI83312.1 - 3.5e-07 29.7 27.8 3.5e-07 29.7 27.8 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AFI83312.1 - 2e-06 27.5 16.5 2e-06 27.5 16.5 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF3671 PF12420.8 AFI83312.1 - 5.4 7.1 7.7 0.83 9.8 1.5 2.6 2 2 0 2 2 2 0 Protein of unknown function NosL PF05573.12 AFI83313.1 - 3.1e-51 173.1 0.4 3.7e-51 172.9 0.4 1.0 1 0 0 1 1 1 1 NosL NRDD PF13597.6 AFI83314.1 - 2.9e-173 577.7 0.0 4.4e-173 577.1 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase ATP-cone PF03477.16 AFI83314.1 - 6.4e-21 74.7 0.8 1.3e-20 73.8 0.8 1.5 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.6 AFI83315.1 - 2.4e-08 33.3 0.4 2.7e-08 33.1 0.4 1.0 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Radical_SAM PF04055.21 AFI83316.1 - 1.8e-16 61.0 0.0 2.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AFI83316.1 - 1.5e-09 38.3 0.0 2.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AFI83316.1 - 8.4e-06 25.9 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Hydrolase_6 PF13344.6 AFI83316.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SOR_SNZ PF01680.17 AFI83317.1 - 1.3e-109 364.8 1.5 1.8e-109 364.3 1.5 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 AFI83317.1 - 8.6e-08 31.8 6.6 7.9e-06 25.4 1.0 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AFI83317.1 - 0.0017 17.9 0.2 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 AFI83317.1 - 0.0039 16.6 2.7 0.004 16.6 0.4 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase NanE PF04131.14 AFI83317.1 - 0.014 14.6 1.6 0.12 11.6 0.0 2.8 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 AFI83317.1 - 0.028 13.5 0.3 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 AFI83317.1 - 0.082 12.2 0.6 4.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase IGPS PF00218.21 AFI83317.1 - 0.11 11.6 0.2 1.1 8.3 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase SNO PF01174.19 AFI83318.1 - 2.8e-47 161.0 0.0 3.4e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AFI83318.1 - 2.6e-07 30.5 0.0 7.8e-07 28.9 0.0 1.6 1 1 1 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AFI83318.1 - 0.0047 16.7 0.1 0.025 14.3 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 AFI83318.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 1 0 1 1 1 0 Peptidase family S51 MoCF_biosynth PF00994.24 AFI83319.1 - 2.1e-30 105.3 0.0 2.5e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain SCP2 PF02036.17 AFI83320.1 - 8.8e-19 67.9 0.1 1.2e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 AFI83320.1 - 0.00015 22.0 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MDMPI_C PF07398.11 AFI83320.1 - 0.0002 22.2 0.0 0.00027 21.7 0.0 1.2 1 0 0 1 1 1 1 MDMPI C-terminal domain Tube PF17212.3 AFI83320.1 - 0.12 12.5 0.0 5.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Tail tubular protein Peptidase_U32 PF01136.19 AFI83321.1 - 2.8e-65 219.8 0.0 3.6e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family U32 AP_endonuc_2 PF01261.24 AFI83321.1 - 0.0059 16.1 0.1 0.0097 15.4 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SAM_MT PF04445.13 AFI83321.1 - 0.16 11.4 0.1 0.29 10.5 0.0 1.4 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Peptidase_U32 PF01136.19 AFI83322.1 - 4.1e-17 62.1 0.0 5.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family U32 Cytochrome_CBB3 PF13442.6 AFI83323.2 - 4e-11 43.1 0.1 7.9e-11 42.1 0.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AFI83323.2 - 4.1e-11 43.9 0.0 6.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 AFI83323.2 - 0.00065 19.4 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome c-550 domain Cyc-maltodext_C PF10438.9 AFI83323.2 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Not3 PF04065.15 AFI83326.1 - 0.032 13.7 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component FAM150 PF15129.6 AFI83326.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 FAM150 family CopD PF05425.13 AFI83327.1 - 3.2e-07 30.7 4.2 3.2e-07 30.7 4.2 1.7 2 0 0 2 2 2 1 Copper resistance protein D DUF2269 PF10027.9 AFI83327.1 - 0.31 11.1 17.1 0.05 13.7 8.0 2.5 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) GAPT PF11770.8 AFI83327.1 - 5.8 6.8 5.6 15 5.4 0.1 2.6 1 1 2 3 3 3 0 GRB2-binding adapter (GAPT) MFS_1 PF07690.16 AFI83328.1 - 1.9e-45 155.3 134.3 9e-27 93.9 44.3 4.0 1 1 3 4 4 4 3 Major Facilitator Superfamily Sprouty PF05210.13 AFI83328.1 - 0.2 12.0 0.5 0.68 10.3 0.1 2.1 2 0 0 2 2 2 0 Sprouty protein (Spry) Rotamase_3 PF13616.6 AFI83329.1 - 2e-21 76.7 0.0 3.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AFI83329.1 - 6.6e-21 75.1 0.0 1.3e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AFI83329.1 - 1.1e-06 29.5 0.0 1.8e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Olduvai PF06758.13 AFI83329.1 - 0.067 13.5 0.5 0.19 12.0 0.3 1.8 1 1 0 1 1 1 0 Olduvai domain Nitrate_red_gam PF02665.14 AFI83330.1 - 4.3e-83 278.2 11.9 4.8e-83 278.0 11.9 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit ResB PF05140.14 AFI83330.1 - 0.02 13.6 0.4 0.026 13.3 0.4 1.1 1 0 0 1 1 1 0 ResB-like family DHHC PF01529.20 AFI83330.1 - 0.47 10.6 4.3 14 5.8 4.3 2.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Nitrate_red_del PF02613.15 AFI83331.1 - 1.4e-09 38.1 0.7 1.4e-09 38.1 0.7 1.7 2 0 0 2 2 2 1 Nitrate reductase delta subunit Fer4_11 PF13247.6 AFI83332.1 - 3.3e-38 129.8 6.2 1e-37 128.3 6.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 AFI83332.1 - 6.3e-31 105.9 0.1 1.6e-30 104.7 0.1 1.7 2 0 0 2 2 2 1 Respiratory nitrate reductase beta C-terminal Fer4_10 PF13237.6 AFI83332.1 - 2.7e-09 37.0 16.0 2.1e-06 27.7 3.9 3.4 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI83332.1 - 1.7e-07 31.7 19.0 9e-05 23.0 5.7 3.7 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI83332.1 - 4.6e-06 26.5 19.0 0.0018 18.3 0.2 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 AFI83332.1 - 0.0002 21.5 18.9 0.22 11.7 0.3 3.3 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AFI83332.1 - 0.0028 17.4 24.1 0.016 15.0 2.0 4.7 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_2 PF12797.7 AFI83332.1 - 0.003 17.6 22.4 0.015 15.4 1.9 4.0 4 0 0 4 4 3 3 4Fe-4S binding domain Fer4_13 PF13370.6 AFI83332.1 - 0.006 17.1 7.2 0.039 14.5 0.1 3.5 3 0 0 3 3 3 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_21 PF14697.6 AFI83332.1 - 0.019 15.1 21.1 0.048 13.8 4.1 3.1 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AFI83332.1 - 0.019 15.7 7.8 1.4 9.7 0.1 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 AFI83332.1 - 0.024 15.2 14.5 1 9.9 0.2 3.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI83332.1 - 0.066 13.8 1.2 0.066 13.8 1.2 3.9 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_8 PF13183.6 AFI83332.1 - 0.18 12.3 0.1 0.18 12.3 0.1 3.8 3 1 0 3 3 1 0 4Fe-4S dicluster domain Fusion_gly PF00523.18 AFI83332.1 - 0.23 9.6 0.1 0.39 8.9 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Fer4_16 PF13484.6 AFI83332.1 - 3 8.8 16.4 51 4.9 0.1 3.9 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Molybdopterin PF00384.22 AFI83333.1 - 2.8e-156 520.8 0.0 3.5e-156 520.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI83333.1 - 9.3e-21 73.9 0.1 1.9e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Nitr_red_alph_N PF14710.6 AFI83333.1 - 3.8e-17 62.5 3.9 1.1e-16 61.0 3.9 1.9 1 0 0 1 1 1 1 Respiratory nitrate reductase alpha N-terminal Molybdop_Fe4S4 PF04879.16 AFI83333.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain VWA PF00092.28 AFI83334.1 - 4.5e-05 23.8 0.0 9.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 AFI83334.1 - 0.0013 18.6 0.0 0.0059 16.6 0.0 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AFI83334.1 - 0.0018 17.7 2.2 0.023 14.1 0.7 2.8 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein AAA_5 PF07728.14 AFI83335.1 - 1e-34 119.5 0.0 2e-34 118.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 AFI83335.1 - 9.9e-26 89.8 0.4 1.7e-25 89.1 0.4 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Sigma54_activat PF00158.26 AFI83335.1 - 0.00027 20.7 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AFI83335.1 - 0.00032 20.1 0.1 0.22 10.9 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AFI83335.1 - 0.00032 20.5 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 AFI83335.1 - 0.00049 19.2 0.0 0.0039 16.2 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 AFI83335.1 - 0.00054 20.4 0.0 0.00083 19.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI83335.1 - 0.00088 19.7 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 AFI83335.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AFI83335.1 - 0.042 13.9 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AFI83335.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AFI83335.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 AFI83335.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 AFI83335.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AFI83335.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AFI83335.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain COX1 PF00115.20 AFI83336.1 - 1.3e-57 195.6 62.0 1.7e-57 195.2 62.0 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_C PF00034.21 AFI83337.1 - 2e-20 73.7 0.0 2.3e-10 41.5 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AFI83337.1 - 6.2e-11 42.5 0.2 0.00076 19.8 0.0 3.3 2 1 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DUF2059 PF09832.9 AFI83337.1 - 0.01 15.8 0.5 0.85 9.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) Cytochrome_C7 PF14522.6 AFI83337.1 - 0.01 15.8 0.4 6 6.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 AFI83337.1 - 0.024 15.1 0.6 6.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c3 FixO PF02433.15 AFI83337.1 - 0.03 13.8 2.4 0.78 9.2 0.0 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase, mono-heme subunit/FixO DHC PF09626.10 AFI83337.1 - 0.043 14.7 2.0 1.4 9.8 0.1 3.1 3 0 0 3 3 3 0 Dihaem cytochrome c MCR PF18509.1 AFI83337.1 - 0.07 12.7 5.4 0.16 11.6 0.4 2.3 2 0 0 2 2 2 0 Magnetochrome domain Cytochrom_CIII PF02085.16 AFI83337.1 - 0.092 13.1 0.4 9.4 6.6 0.2 2.2 2 0 0 2 2 2 0 Class III cytochrome C family DUF1924 PF09086.11 AFI83337.1 - 0.58 10.6 2.1 2.8 8.4 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1924) 2TM PF13239.6 AFI83338.1 - 0.1 12.9 0.8 0.11 12.9 0.8 1.1 1 0 0 1 1 1 0 2TM domain Radical_SAM PF04055.21 AFI83341.1 - 3.1e-15 56.9 0.0 4.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AFI83341.1 - 3.2e-11 43.1 0.2 9.8e-11 41.6 0.2 1.9 1 0 0 1 1 1 1 HemN C-terminal domain Lysine_decarbox PF03641.14 AFI83342.1 - 8.9e-32 110.0 0.0 1.5e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AFI83342.1 - 2.5e-14 53.2 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AFI83342.1 - 0.00063 19.1 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 DNA recombination-mediator protein A SipA_VBS PF17985.1 AFI83342.1 - 0.025 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 SipA vinculin binding site STALD PF18185.1 AFI83342.1 - 0.055 12.8 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family LacAB_rpiB PF02502.18 AFI83342.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribose/Galactose Isomerase GARS_A PF01071.19 AFI83343.1 - 5.2e-80 267.8 0.1 7.5e-80 267.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AFI83343.1 - 5.6e-38 129.6 0.0 1.2e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AFI83343.1 - 2e-30 104.9 5.5 4.2e-30 103.9 2.7 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 AFI83343.1 - 1e-05 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AFI83343.1 - 0.0003 20.3 0.1 0.00056 19.5 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AFI83343.1 - 0.00038 20.1 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AFI83343.1 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 AFI83343.1 - 0.015 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AFI83343.1 - 0.066 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 AFI83343.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PRK PF00485.18 AFI83344.1 - 3.9e-69 232.3 0.0 5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family XS PF03468.14 AFI83344.1 - 0.0038 17.5 0.1 0.0072 16.6 0.1 1.6 1 0 0 1 1 1 1 XS domain Zeta_toxin PF06414.12 AFI83344.1 - 0.02 14.2 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin PAS_10 PF13596.6 AFI83344.1 - 0.1 13.2 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain Sua5_yciO_yrdC PF01300.18 AFI83345.1 - 9e-38 129.5 0.0 1e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Coprogen_oxidas PF01218.18 AFI83346.1 - 1.1e-136 454.4 0.0 1.2e-136 454.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PCRF PF03462.18 AFI83347.1 - 1.2e-73 247.1 2.9 1.9e-73 246.5 0.3 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AFI83347.1 - 2.1e-42 143.7 2.0 2.1e-42 143.7 2.0 1.7 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 AFI83347.1 - 0.0094 16.2 0.0 0.0094 16.2 0.0 3.0 3 0 0 3 3 3 1 ABC transporter C-terminal domain MIR PF02815.19 AFI83347.1 - 0.055 13.3 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 MIR domain GlutR_N PF05201.15 AFI83348.1 - 3.7e-50 169.5 0.0 1e-49 168.1 0.0 1.8 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AFI83348.1 - 1.5e-47 161.1 0.2 3.3e-47 160.0 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AFI83348.1 - 2.2e-25 88.9 1.0 5.1e-25 87.8 1.0 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 AFI83348.1 - 0.002 17.1 0.4 0.0071 15.3 0.1 1.8 1 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 AFI83348.1 - 0.0091 16.6 0.5 0.028 15.0 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 AFI83348.1 - 0.14 12.6 0.3 0.45 11.0 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding TPR_2 PF07719.17 AFI83349.1 - 2.6e-27 92.7 25.3 4.5e-05 23.2 0.5 13.1 12 1 2 14 14 14 3 Tetratricopeptide repeat TPR_16 PF13432.6 AFI83349.1 - 2.7e-20 72.7 17.3 0.0002 21.9 0.0 9.0 5 1 5 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 AFI83349.1 - 5e-20 70.5 26.1 0.32 11.9 0.1 11.5 3 3 9 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 AFI83349.1 - 1.2e-19 70.5 31.4 0.0015 19.0 0.0 8.9 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 AFI83349.1 - 2.8e-18 64.9 12.8 0.00045 19.9 0.1 9.6 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 AFI83349.1 - 5.5e-18 63.6 15.7 0.0042 17.2 0.0 10.6 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 AFI83349.1 - 2.7e-14 53.2 26.8 3.9e-09 36.7 3.0 9.4 4 2 6 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 AFI83349.1 - 8.6e-14 50.9 19.9 0.0039 17.5 0.2 9.5 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 AFI83349.1 - 8.8e-13 47.7 13.8 0.00022 20.8 0.1 8.5 7 1 2 9 9 9 3 TPR repeat TPR_15 PF13429.6 AFI83349.1 - 1.4e-10 40.9 18.7 0.0026 17.0 0.2 5.4 2 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 AFI83349.1 - 2.4e-09 37.2 18.1 5.5e-05 23.2 0.3 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI83349.1 - 3.7e-09 36.7 7.2 0.00035 20.7 0.1 5.1 3 1 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 AFI83349.1 - 2e-08 33.7 4.3 0.54 9.1 0.0 4.8 3 2 2 5 5 5 4 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 AFI83349.1 - 6.8e-07 29.5 20.0 2.4 9.0 0.2 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 AFI83349.1 - 8.7e-07 28.6 26.3 0.00022 21.0 0.3 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AFI83349.1 - 2.4e-05 24.3 12.9 4.7 7.4 0.3 7.1 4 2 3 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 AFI83349.1 - 2.6e-05 24.4 2.8 1.1 10.1 0.0 7.2 9 0 0 9 9 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 AFI83349.1 - 0.00015 20.7 0.7 0.33 9.6 0.1 2.8 1 1 2 3 3 3 3 Protein kinase G tetratricopeptide repeat TPR_MalT PF17874.1 AFI83349.1 - 0.0005 19.6 11.0 0.58 9.5 0.5 5.1 2 1 2 5 5 5 1 MalT-like TPR region HrpB1_HrpK PF09613.10 AFI83349.1 - 0.00052 19.7 2.7 0.74 9.5 0.1 4.0 4 1 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) Mad3_BUB1_I_2 PF17014.5 AFI83349.1 - 0.0016 18.6 0.0 0.24 11.5 0.0 3.1 3 0 0 3 3 3 1 Putative Mad3/BUB1 like region 1 protein TPR_7 PF13176.6 AFI83349.1 - 0.0031 17.4 14.7 5.6 7.2 0.1 7.9 7 2 2 9 9 8 1 Tetratricopeptide repeat PPR PF01535.20 AFI83349.1 - 0.004 17.3 2.2 41 4.7 0.1 5.7 6 0 0 6 6 5 0 PPR repeat TPR_21 PF09976.9 AFI83349.1 - 0.0087 15.8 10.3 0.56 9.9 0.1 4.0 3 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 AFI83349.1 - 0.0098 15.9 5.0 31 4.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat FAT PF02259.23 AFI83349.1 - 0.011 14.9 1.9 4 6.6 0.1 3.3 1 1 0 2 2 2 0 FAT domain DUF5113 PF17140.4 AFI83349.1 - 0.14 12.0 1.0 0.88 9.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) LolB PF03550.14 AFI83350.1 - 5.7e-43 146.6 0.1 6.8e-43 146.4 0.1 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein LolB DUF5535 PF17687.1 AFI83350.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5535) GHMP_kinases_N PF00288.26 AFI83351.1 - 8e-11 42.0 0.1 1.8e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AFI83351.1 - 2.3e-05 24.7 0.0 4.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GH97_C PF14509.6 AFI83351.1 - 0.12 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Pribosyltran_N PF13793.6 AFI83352.1 - 8.8e-49 164.3 0.5 2.6e-48 162.8 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AFI83352.1 - 6.3e-29 101.3 2.3 6.8e-28 97.9 0.8 2.4 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AFI83352.1 - 6.6e-20 71.2 4.0 1.5e-19 70.1 0.9 2.6 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AFI83352.1 - 0.031 13.7 0.2 0.055 12.9 0.2 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_TL5_C PF14693.6 AFI83353.1 - 9.8e-33 112.4 0.3 2.1e-32 111.3 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AFI83353.1 - 1.2e-26 93.0 0.8 2e-26 92.3 0.4 1.6 2 0 0 2 2 2 1 Ribosomal L25p family DUF550 PF04447.12 AFI83353.1 - 0.024 14.7 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Pept_tRNA_hydro PF01195.19 AFI83354.1 - 6.9e-61 205.2 0.0 7.7e-61 205.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase YchF-GTPase_C PF06071.13 AFI83355.1 - 2.1e-38 130.3 1.2 3.2e-38 129.8 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AFI83355.1 - 8.9e-23 80.6 0.0 1.8e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI83355.1 - 6.9e-08 32.2 0.1 2.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 AFI83355.1 - 0.00035 20.5 0.3 0.027 14.5 0.0 3.1 3 0 0 3 3 3 1 TGS domain PLA1 PF02253.15 AFI83356.1 - 7.2e-102 340.4 5.9 8.9e-102 340.1 5.9 1.1 1 0 0 1 1 1 1 Phospholipase A1 MS_channel PF00924.18 AFI83357.1 - 4.2e-43 147.3 1.8 6.9e-43 146.6 1.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Myco_arth_vir_N PF09610.10 AFI83357.1 - 1.8 8.7 3.8 1.7 8.8 1.3 2.3 1 1 1 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Phage_holin_2_2 PF10746.9 AFI83357.1 - 2.4 7.9 6.2 0.53 10.0 1.7 2.2 2 1 0 2 2 2 0 Phage holin T7 family, holin superfamily II DDE_Tnp_1_2 PF13586.6 AFI83359.1 - 6.2e-18 65.0 0.7 7e-18 64.8 0.7 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI83359.1 - 3.9e-10 39.7 4.2 4e-08 33.2 4.2 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AFI83359.1 - 1.1e-06 28.7 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI83359.1 - 4.9e-06 26.3 0.1 6e-06 26.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Cellulase PF00150.18 AFI83359.1 - 0.047 13.1 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4096 PF13340.6 AFI83360.1 - 3.7e-25 87.9 3.8 7e-25 87.0 3.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Peptidase_M91 PF14891.6 AFI83362.1 - 0.03 14.6 0.2 0.033 14.5 0.2 1.2 1 0 0 1 1 1 0 Effector protein FG-GAP PF01839.23 AFI83363.1 - 0.01 15.9 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 FG-GAP repeat DUF5305 PF17231.2 AFI83364.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) LapA_dom PF06305.11 AFI83364.1 - 0.082 12.7 0.6 0.19 11.6 0.6 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Gram_pos_anchor PF00746.21 AFI83364.1 - 0.17 11.9 1.6 0.32 11.0 1.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MscL PF01741.18 AFI83365.1 - 9.4e-46 155.1 5.1 1.1e-45 154.9 5.1 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF4577 PF15145.6 AFI83365.1 - 0.14 12.2 0.3 0.24 11.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) S_4TM PF18159.1 AFI83365.1 - 0.28 10.4 1.4 0.69 9.2 0.0 1.8 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF2976 PF11190.8 AFI83365.1 - 0.51 10.2 5.2 0.39 10.5 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) DUF3487 PF11990.8 AFI83365.1 - 1.7 8.5 7.5 0.26 11.2 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) YfhO PF09586.10 AFI83366.1 - 0.0008 17.8 0.6 0.001 17.4 0.6 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF2593 PF10767.9 AFI83366.1 - 0.072 13.2 0.8 0.1 12.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) DUF4149 PF13664.6 AFI83366.1 - 0.6 10.5 9.4 7.3 7.0 9.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Wzy_C PF04932.15 AFI83366.1 - 2.6 7.7 6.3 17 5.0 6.3 2.0 1 1 0 1 1 1 0 O-Antigen ligase DUF751 PF05421.11 AFI83366.1 - 2.6 8.8 6.6 1 10.1 2.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF751) PepSY_TM PF03929.16 AFI83366.1 - 6.9 6.2 8.6 1.8 8.2 0.3 2.3 1 1 1 2 2 2 0 PepSY-associated TM region LysR_substrate PF03466.20 AFI83367.1 - 1.2e-45 155.4 0.3 1.6e-45 155.0 0.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AFI83367.1 - 4.1e-21 74.7 0.4 1.3e-20 73.1 0.4 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 AFI83367.1 - 6.7e-06 25.3 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain Mak_N_cap PF18085.1 AFI83367.1 - 0.013 16.6 0.1 0.42 11.7 0.1 2.7 2 0 0 2 2 2 0 Maltokinase N-terminal cap domain RuBisCO_large PF00016.20 AFI83368.1 - 9.4e-133 442.0 0.2 1.2e-132 441.7 0.2 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.16 AFI83368.1 - 2.4e-44 150.3 0.0 5.2e-44 149.3 0.0 1.6 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain RuBisCO_small PF00101.20 AFI83369.1 - 8.3e-38 128.3 0.0 9.8e-38 128.1 0.0 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain CbbQ_C PF08406.10 AFI83370.1 - 7.8e-34 115.8 0.3 1.4e-33 115.0 0.3 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_5 PF07728.14 AFI83370.1 - 7.1e-33 113.5 0.0 9.9e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 AFI83370.1 - 8.9e-07 28.2 0.0 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 AFI83370.1 - 0.00076 19.2 0.0 0.0021 17.8 0.0 1.7 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 AFI83370.1 - 0.005 17.1 0.0 0.009 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AFI83370.1 - 0.0079 16.1 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 AFI83370.1 - 0.0084 16.5 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI83370.1 - 0.019 14.4 0.0 2.4 7.5 0.0 2.2 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AFI83370.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AFI83370.1 - 0.032 14.6 0.0 0.071 13.5 0.0 1.6 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 AFI83370.1 - 0.054 13.7 0.0 0.094 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain VWA PF00092.28 AFI83371.1 - 7.9e-09 36.0 0.0 2.1e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AFI83371.1 - 4.1e-05 24.2 0.0 0.00031 21.4 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain CobT_C PF11775.8 AFI83371.1 - 0.0089 15.7 0.1 0.17 11.5 0.0 2.6 3 0 0 3 3 3 1 Cobalamin biosynthesis protein CobT VWA domain FCD PF07729.12 AFI83371.1 - 0.051 14.0 0.4 0.28 11.6 0.4 2.3 1 0 0 1 1 1 0 FCD domain EAL PF00563.20 AFI83373.1 - 9.6e-70 234.8 0.1 2.1e-69 233.7 0.1 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI83373.1 - 2.2e-51 173.8 0.6 1e-50 171.6 0.2 2.4 3 0 0 3 3 3 1 Diguanylate cyclase, GGDEF domain NMT1 PF09084.11 AFI83373.1 - 9e-48 163.1 0.1 6.6e-47 160.2 0.0 2.4 3 0 0 3 3 3 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AFI83373.1 - 1.3e-41 142.5 0.1 9.3e-40 136.4 0.1 2.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 PAS_9 PF13426.7 AFI83373.1 - 1.6e-25 89.4 0.1 4e-18 65.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AFI83373.1 - 2.2e-20 72.8 0.0 4.1e-15 55.8 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AFI83373.1 - 1.1e-14 54.0 0.0 2.3e-08 33.9 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AFI83373.1 - 1.7e-10 41.1 0.0 9.3e-08 32.3 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AFI83373.1 - 2.6e-07 30.8 0.1 5.5e-05 23.4 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 AFI83373.1 - 0.14 12.3 0.1 41 4.4 0.0 3.6 3 1 0 3 3 3 0 PAS fold VWA_2 PF13519.6 AFI83374.1 - 1.9e-10 41.3 0.0 3.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TPR_19 PF14559.6 AFI83375.1 - 0.014 15.9 1.7 0.99 10.0 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AFI83375.1 - 0.032 14.4 0.7 24 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI83375.1 - 0.082 12.8 5.6 8.5 6.4 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 AFI83375.1 - 0.53 10.0 5.0 2.2 8.1 0.2 3.3 3 1 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 AFI83375.1 - 0.58 10.7 4.8 40 4.9 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat VWA_2 PF13519.6 AFI83376.1 - 9.4e-17 61.6 0.0 2.3e-16 60.3 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 AFI83376.1 - 1.3e-11 45.1 0.0 1.9e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 AFI83376.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) DUF4381 PF14316.6 AFI83377.1 - 0.00069 19.9 0.9 0.0012 19.1 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF2189 PF09955.9 AFI83377.1 - 0.0035 17.6 0.8 0.0054 17.0 0.1 1.7 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2189) SYF2 PF08231.12 AFI83377.1 - 0.068 13.6 2.9 0.1 13.0 2.9 1.2 1 0 0 1 1 1 0 SYF2 splicing factor HemY_N PF07219.13 AFI83377.1 - 0.19 11.9 0.2 0.19 11.9 0.2 1.7 2 0 0 2 2 2 0 HemY protein N-terminus XG_FTase PF03254.13 AFI83378.1 - 0.0096 14.6 0.1 0.023 13.3 0.0 1.6 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase AAA_3 PF07726.11 AFI83379.1 - 1.8e-25 89.3 0.0 2.6e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI83379.1 - 2.8e-14 53.3 0.0 5.6e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 AFI83379.1 - 9.1e-11 41.5 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain TsaE PF02367.17 AFI83379.1 - 0.00014 21.8 0.1 0.00026 21.0 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AFI83379.1 - 0.00019 21.9 0.0 0.00041 20.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AFI83379.1 - 0.00065 19.5 0.1 0.016 14.9 0.1 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AFI83379.1 - 0.0025 18.2 0.0 0.0072 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AFI83379.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AFI83379.1 - 0.0056 17.2 0.0 0.041 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AFI83379.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 AFI83379.1 - 0.031 14.8 0.1 0.045 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AFI83379.1 - 0.032 14.4 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 AFI83379.1 - 0.033 13.9 0.1 0.53 10.0 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 AFI83379.1 - 0.046 12.8 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 AFI83379.1 - 0.046 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 AFI83379.1 - 0.08 12.0 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 AFI83379.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 AFI83379.1 - 0.083 12.8 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 AFI83379.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase MDH PF02315.16 AFI83380.1 - 9.9e-43 144.1 0.5 1.1e-42 143.9 0.5 1.0 1 0 0 1 1 1 1 Methanol dehydrogenase beta subunit Cytochrome_CBB3 PF13442.6 AFI83381.1 - 4.4e-11 42.9 0.5 8.3e-11 42.1 0.1 1.7 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AFI83381.1 - 2.1e-05 25.5 1.1 0.00034 21.7 0.5 2.7 2 1 0 2 2 2 1 Cytochrome c SBP_bac_3 PF00497.20 AFI83382.1 - 7.2e-17 61.6 0.0 9.9e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PQQ PF01011.21 AFI83383.1 - 1.3e-35 119.7 7.2 4.7e-07 29.4 0.0 7.2 7 0 0 7 7 7 6 PQQ enzyme repeat PQQ_2 PF13360.6 AFI83383.1 - 8.2e-14 51.8 2.8 3.3e-06 26.9 0.6 3.4 3 1 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 AFI83383.1 - 6.3e-10 39.2 3.0 0.012 16.1 0.0 5.7 4 0 0 4 4 4 4 PQQ-like domain Response_reg PF00072.24 AFI83384.1 - 7e-26 90.6 0.0 1.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AFI83384.1 - 6.7e-17 60.8 0.1 1.2e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI83384.1 - 4.4e-05 23.1 0.0 9.2e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AFI83384.1 - 0.0029 18.0 0.0 0.0082 16.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI83384.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 AFI83384.1 - 0.033 13.9 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AFI83384.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AFI83384.1 - 0.1 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HisKA_3 PF07730.13 AFI83385.1 - 1.8e-09 38.0 0.0 5.2e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 AFI83385.1 - 1.1e-06 29.1 0.0 8e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AFI83385.1 - 0.00024 21.1 0.1 0.00055 19.9 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Polyketide_cyc2 PF10604.9 AFI83387.1 - 1.5e-25 90.2 0.0 1.7e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AFI83387.1 - 0.081 13.1 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 AFI83387.1 - 0.14 11.9 0.1 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) Lactonase PF10282.9 AFI83388.1 - 1.4e-16 60.8 0.1 1.7e-06 27.6 0.0 3.1 1 1 2 3 3 3 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AFI83388.1 - 1e-11 44.0 0.2 3.9e-05 22.4 0.0 2.7 1 1 1 3 3 3 3 Cytochrome D1 heme domain NHL PF01436.21 AFI83388.1 - 7.6e-10 38.3 1.6 0.034 14.2 0.0 5.8 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 AFI83388.1 - 7.2e-08 32.3 0.1 0.0056 16.3 0.0 3.7 1 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF4221 PF13970.6 AFI83388.1 - 1.4e-06 28.1 2.4 0.19 11.2 0.3 3.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4221) DUF5128 PF17170.4 AFI83388.1 - 3.9e-06 26.2 0.1 0.24 10.5 0.1 3.2 1 1 2 3 3 3 3 6-bladed beta-propeller Arylesterase PF01731.20 AFI83388.1 - 5.6e-05 23.3 0.0 0.047 13.9 0.0 3.8 2 2 1 3 3 3 1 Arylesterase Glu_cyclase_2 PF05096.12 AFI83388.1 - 0.00022 20.8 0.2 0.0051 16.3 0.1 2.5 1 1 2 3 3 3 1 Glutamine cyclotransferase Me-amine-dh_H PF06433.11 AFI83388.1 - 0.0021 17.0 0.4 0.042 12.7 0.1 2.8 2 1 1 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) Beta_propel PF09826.9 AFI83388.1 - 0.0079 15.1 0.6 0.78 8.5 0.2 2.6 1 1 1 3 3 3 1 Beta propeller domain DUF1513 PF07433.11 AFI83388.1 - 0.01 14.9 0.0 28 3.6 0.0 4.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1513) DKNYY PF13644.6 AFI83388.1 - 0.025 15.4 0.0 0.3 11.8 0.0 2.3 1 1 0 1 1 1 0 DKNYY family HPS6 PF15702.5 AFI83388.1 - 0.14 10.1 0.0 0.78 7.7 0.0 1.9 1 1 0 2 2 2 0 Hermansky-Pudlak syndrome 6 protein SpoU_methylase PF00588.19 AFI83389.1 - 5.5e-34 117.4 0.0 6.1e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Malate_DH PF12434.8 AFI83389.1 - 0.0049 16.9 0.2 0.0098 15.9 0.2 1.4 1 0 0 1 1 1 1 Malate dehydrogenase enzyme LysM PF01476.20 AFI83390.1 - 5.5e-40 135.2 2.3 5.4e-14 52.0 0.2 3.9 4 0 0 4 4 4 3 LysM domain SLT PF01464.20 AFI83390.1 - 5.2e-24 84.2 0.0 1.1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain OapA PF04225.12 AFI83390.1 - 0.044 13.9 0.0 35 4.6 0.0 3.3 2 1 1 3 3 3 0 Opacity-associated protein A LysM-like domain DUF2797 PF10977.8 AFI83391.1 - 2.3e-96 322.2 0.1 2.6e-96 322.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) DHO_dh PF01180.21 AFI83392.1 - 2.3e-87 293.0 0.0 2.8e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 AFI83392.1 - 1.9e-06 27.5 0.1 2.6e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 AFI83392.1 - 0.0026 17.3 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF3372 PF11852.8 AFI83392.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) G3P_antiterm PF04309.12 AFI83392.1 - 0.024 14.1 0.0 0.075 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 AFI83392.1 - 0.029 13.4 0.0 0.084 11.9 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Dus PF01207.17 AFI83392.1 - 0.05 12.7 0.1 0.16 11.1 0.1 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) IMPDH PF00478.25 AFI83392.1 - 0.065 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Fe-ADH PF00465.19 AFI83392.1 - 0.09 11.6 0.7 0.65 8.7 0.0 2.2 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase DUF4358 PF14270.6 AFI83392.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) PcrB PF01884.17 AFI83392.1 - 0.17 11.3 0.2 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 PcrB family MS_channel PF00924.18 AFI83393.1 - 8.3e-56 188.8 4.6 1.1e-55 188.4 4.6 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel TM_helix PF05552.12 AFI83393.1 - 0.0014 18.6 2.7 0.0014 18.6 2.7 2.1 1 1 1 2 2 2 1 Conserved TM helix AP_endonuc_2 PF01261.24 AFI83393.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HAGH_C PF16123.5 AFI83394.1 - 1e-26 93.2 0.3 1.7e-26 92.6 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AFI83394.1 - 1.8e-18 67.3 4.8 6.2e-17 62.2 4.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AFI83394.1 - 0.0036 16.8 2.8 0.0075 15.8 2.5 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AFI83394.1 - 0.072 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Methyltransf_11 PF08241.12 AFI83395.1 - 1.7e-08 35.0 0.0 3.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83395.1 - 6e-06 26.2 0.2 7.7e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AFI83395.1 - 0.0019 17.6 0.0 0.0038 16.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AFI83395.1 - 0.007 17.0 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AFI83395.1 - 0.017 14.7 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 AFI83395.1 - 0.045 13.5 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83395.1 - 0.16 12.7 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNase_H PF00075.24 AFI83396.1 - 7e-50 168.9 0.0 7.8e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 AFI83396.1 - 9.4e-05 22.2 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_T PF00929.24 AFI83397.1 - 2.2e-40 138.9 0.3 3.2e-40 138.4 0.3 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 AFI83397.1 - 0.0001 22.4 0.0 0.00062 19.8 0.0 2.1 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 AFI83397.1 - 0.00092 19.0 1.0 0.067 12.9 0.2 2.4 2 1 0 2 2 2 2 3'-5' exonuclease KR PF08659.10 AFI83397.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 KR domain GrpE PF01025.19 AFI83398.1 - 1.1e-50 171.5 1.9 1.3e-50 171.3 1.9 1.1 1 0 0 1 1 1 1 GrpE DUF1087 PF06465.13 AFI83398.1 - 0.28 11.3 3.5 0.22 11.6 1.8 1.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1087) HSP70 PF00012.20 AFI83399.1 - 6.4e-266 883.3 18.7 7.4e-266 883.1 18.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AFI83399.1 - 1.6e-18 66.6 3.7 1.4e-14 53.7 0.6 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 AFI83399.1 - 0.0045 17.4 9.3 0.52 10.8 0.2 3.6 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 AFI83399.1 - 0.0074 15.6 2.1 0.027 13.7 0.2 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 AFI83399.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1090 PF06476.12 AFI83399.1 - 0.53 10.4 8.0 1.4 9.0 8.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DnaJ_C PF01556.18 AFI83400.1 - 4.2e-43 147.0 0.0 5.3e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AFI83400.1 - 1e-27 96.0 2.8 1.7e-27 95.4 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AFI83400.1 - 1.7e-14 53.9 19.1 3.9e-14 52.8 19.1 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AFI83400.1 - 0.00018 21.4 19.7 0.0067 16.4 5.6 3.2 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein LTXXQ PF07813.12 AFI83400.1 - 0.012 16.3 0.9 3.5 8.4 0.2 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein HypA PF01155.19 AFI83400.1 - 0.035 14.1 1.0 0.035 14.1 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 AFI83400.1 - 0.7 9.5 7.0 0.72 9.5 1.0 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 RseC_MucC PF04246.12 AFI83400.1 - 1.9 8.4 7.7 4.5 7.2 3.3 2.3 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC zinc-ribbons_6 PF07191.12 AFI83400.1 - 4.3 7.4 7.9 11 6.1 7.9 1.7 1 1 0 1 1 1 0 zinc-ribbons A2L_zn_ribbon PF08792.10 AFI83400.1 - 4.4 7.1 9.4 3.8 7.3 0.2 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain DapB_C PF05173.14 AFI83401.1 - 1.7e-42 144.3 0.1 2.3e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 AFI83401.1 - 3.8e-41 140.1 0.9 1.1e-40 138.6 0.1 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 AFI83401.1 - 0.029 14.7 0.0 0.096 13.0 0.0 1.9 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AFI83401.1 - 0.043 14.1 0.2 0.16 12.2 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 AFI83401.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TPR_8 PF13181.6 AFI83402.1 - 5.2e-07 29.4 5.5 0.021 15.0 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AFI83402.1 - 1.7e-06 28.4 5.7 7.5e-05 23.2 1.2 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AFI83402.1 - 2.8e-06 27.9 5.8 8.3e-05 23.2 2.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 AFI83402.1 - 3.8e-06 26.5 3.5 7e-06 25.6 3.5 1.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_11 PF13414.6 AFI83402.1 - 1.9e-05 24.2 1.4 4.6e-05 23.0 1.4 1.7 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 AFI83402.1 - 2.8e-05 24.2 3.0 0.0011 19.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AFI83402.1 - 0.00057 19.8 9.0 0.037 14.1 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AFI83402.1 - 0.001 19.7 6.1 0.02 15.7 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AFI83402.1 - 0.0069 16.2 4.4 0.13 12.1 0.5 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI83402.1 - 0.0093 16.2 0.5 0.018 15.3 0.4 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AFI83402.1 - 0.017 15.1 4.2 14 6.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AFI83402.1 - 0.047 13.8 2.1 0.054 13.7 0.3 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AFI83402.1 - 0.058 13.7 6.5 0.17 12.2 3.6 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 AFI83402.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.3 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 AFI83402.1 - 5.9 7.7 11.2 15 6.4 0.8 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Transgly PF00912.22 AFI83404.1 - 8.1e-58 194.8 0.0 1.3e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AFI83404.1 - 1.4e-24 86.9 0.0 5.9e-24 84.8 0.0 1.8 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain UB2H PF14814.6 AFI83404.1 - 4.4e-23 81.1 0.0 8.9e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain DUF898 PF05987.13 AFI83405.1 - 5.3e-101 338.1 31.2 1.3e-100 336.8 31.2 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF4658 PF15555.6 AFI83405.1 - 0.06 13.5 0.0 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Peptidase_M48 PF01435.18 AFI83406.1 - 4e-25 88.7 0.2 8.4e-25 87.7 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.6 AFI83406.1 - 0.06 12.9 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain AhpC-TSA PF00578.21 AFI83407.1 - 8.6e-21 74.1 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AFI83407.1 - 3.9e-14 52.6 0.0 5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 AFI83407.1 - 0.0001 22.7 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AFI83407.1 - 0.0078 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.6 AFI83407.1 - 0.091 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Transketolase_N PF00456.21 AFI83408.1 - 4.6e-163 541.9 0.2 6.2e-163 541.5 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AFI83408.1 - 4.9e-44 150.1 0.0 8.6e-44 149.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AFI83408.1 - 1.5e-16 60.4 0.2 5e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 AFI83408.1 - 1.1e-05 24.6 0.1 2.6e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 AFI83408.1 - 7.4e-05 22.1 0.0 0.07 12.3 0.0 3.0 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AFI83408.1 - 0.0058 16.4 0.6 4.1 7.2 0.0 2.8 1 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Gp_dh_C PF02800.20 AFI83409.1 - 4.7e-68 227.8 0.0 6.6e-68 227.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AFI83409.1 - 2.5e-40 136.9 0.0 5.5e-40 135.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PGK PF00162.19 AFI83410.1 - 6.7e-143 476.2 0.3 7.6e-143 476.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PK PF00224.21 AFI83411.1 - 3.4e-115 384.6 3.7 3.4e-115 384.6 3.7 2.0 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AFI83411.1 - 7.1e-32 110.1 0.4 2.8e-31 108.2 0.3 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 AFI83411.1 - 0.00048 19.2 0.5 0.00092 18.3 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain HpcH_HpaI PF03328.14 AFI83411.1 - 0.0095 15.1 0.7 0.0095 15.1 0.7 3.0 3 0 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family DUF3006 PF11213.8 AFI83411.1 - 0.021 15.0 1.8 1.6 9.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3006) PhnA PF03831.14 AFI83411.1 - 0.17 11.8 3.5 0.31 10.9 0.6 2.8 3 0 0 3 3 3 0 PhnA domain F_bP_aldolase PF01116.20 AFI83412.1 - 1e-88 297.5 0.1 1.3e-88 297.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CRCB PF02537.15 AFI83413.1 - 1.2e-24 86.4 12.3 1.4e-24 86.2 12.3 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Vma12 PF11712.8 AFI83413.1 - 0.055 13.5 2.0 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP19 PF11022.8 AFI83413.1 - 0.093 13.1 1.1 0.32 11.4 0.1 2.2 1 1 1 2 2 2 0 ATP synthase subunit K DUF190 PF02641.15 AFI83414.1 - 3.4e-18 65.8 0.0 4.5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 RLL PF10036.9 AFI83414.1 - 0.063 13.1 0.1 0.11 12.4 0.1 1.3 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein tRNA-synt_2b PF00587.25 AFI83415.1 - 2.5e-34 118.8 0.0 4.2e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AFI83415.1 - 3.4e-30 104.5 2.5 6.8e-30 103.5 2.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 AFI83415.1 - 0.011 16.2 4.6 0.031 14.7 4.6 1.8 1 0 0 1 1 1 0 Cell division protein ZapB Cep57_CLD PF14073.6 AFI83415.1 - 0.022 14.8 0.8 0.046 13.7 0.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 SBF2 PF12335.8 AFI83415.1 - 0.032 13.9 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Myotubularin protein TMF_TATA_bd PF12325.8 AFI83415.1 - 0.083 13.1 4.9 0.15 12.3 2.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 AFI83415.1 - 1.2 9.7 3.6 2.7 8.5 1.5 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Peptidase_M50 PF02163.22 AFI83416.1 - 1.9e-07 30.6 13.1 5.7e-05 22.5 2.5 3.0 1 1 1 2 2 2 2 Peptidase family M50 tRNA-synt_1b PF00579.25 AFI83417.1 - 4.4e-62 210.1 0.0 6.2e-48 163.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Cytidylate_kin2 PF13189.6 AFI83417.1 - 0.014 15.5 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family BshC PF10079.9 AFI83417.1 - 0.3 9.8 1.6 0.44 9.2 1.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PseudoU_synth_2 PF00849.22 AFI83418.1 - 2.3e-16 60.3 0.0 4.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AFI83418.1 - 5.6e-11 42.0 0.1 1.1e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 S4 domain GGDEF PF00990.21 AFI83419.1 - 1.2e-46 158.4 0.3 1.9e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AFI83419.1 - 0.00084 19.6 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 GGDEF-like domain adh_short PF00106.25 AFI83420.1 - 3.8e-37 127.6 0.1 4.4e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AFI83420.1 - 7.1e-36 123.9 0.0 2.1e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AFI83420.1 - 5.2e-11 42.8 0.2 7.3e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AFI83420.1 - 9.5e-08 31.8 0.2 5.2e-07 29.4 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AFI83420.1 - 2.8e-07 30.0 0.0 3.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 AFI83420.1 - 0.0034 16.8 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 AFI83420.1 - 0.02 14.7 0.1 0.054 13.3 0.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AlaDh_PNT_C PF01262.21 AFI83420.1 - 0.046 13.0 0.8 1.2 8.4 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AFI83420.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 AFI83420.1 - 0.11 11.6 0.1 0.25 10.4 0.1 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 AFI83420.1 - 0.14 11.5 0.1 0.28 10.5 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF3862 PF12978.7 AFI83421.1 - 6.1e-05 22.9 0.0 8.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3862) DUF4972 PF16342.5 AFI83421.1 - 0.02 14.6 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Amino_oxidase PF01593.24 AFI83422.1 - 2.7e-33 116.0 0.0 3.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AFI83422.1 - 6.4e-11 42.3 0.8 2.1e-10 40.6 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AFI83422.1 - 2.7e-07 30.5 0.1 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AFI83422.1 - 2.8e-06 26.8 0.1 0.068 12.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AFI83422.1 - 3.2e-05 23.2 0.3 0.00047 19.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AFI83422.1 - 9.4e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AFI83422.1 - 0.00011 21.1 0.8 0.0096 14.7 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 AFI83422.1 - 0.00013 21.2 1.7 0.077 12.1 0.2 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A MCRA PF06100.11 AFI83422.1 - 0.027 13.3 0.1 0.077 11.8 0.0 1.7 2 0 0 2 2 2 0 MCRA family Thi4 PF01946.17 AFI83422.1 - 0.1 11.8 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 AFI83422.1 - 0.11 13.1 0.1 1.2 9.8 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SQS_PSY PF00494.19 AFI83423.1 - 1.8e-81 273.5 1.6 2.1e-81 273.3 1.6 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF2824 PF11039.8 AFI83423.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Suc_Fer-like PF06999.12 AFI83424.1 - 0.01 15.7 0.1 0.01 15.7 0.1 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like polyprenyl_synt PF00348.17 AFI83425.1 - 1.4e-76 257.0 1.0 1.8e-76 256.6 1.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L21p PF00829.21 AFI83426.1 - 2.6e-42 143.1 1.9 2.9e-42 143.0 1.9 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Biotin_lipoyl PF00364.22 AFI83426.1 - 0.013 15.3 2.4 3 7.7 0.2 2.9 1 1 2 3 3 3 0 Biotin-requiring enzyme Ribosomal_L27 PF01016.19 AFI83427.1 - 1.5e-36 124.2 3.7 1.7e-36 124.1 3.7 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein RCC1_2 PF13540.6 AFI83427.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat GTP1_OBG PF01018.22 AFI83428.1 - 6.6e-60 201.2 2.0 6.6e-60 201.2 2.0 1.5 2 0 0 2 2 2 1 GTP1/OBG MMR_HSR1 PF01926.23 AFI83428.1 - 4.7e-23 81.5 0.0 7.3e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI83428.1 - 1.8e-09 37.3 0.0 1.7e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 AFI83428.1 - 2.1e-06 27.0 0.0 0.0053 15.8 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 AFI83428.1 - 0.0033 17.0 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AFI83428.1 - 0.0034 17.3 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 AFI83428.1 - 0.0044 16.5 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 AFI83428.1 - 0.1 12.4 0.0 11 5.8 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 AFI83428.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PCDO_beta_N PF12391.8 AFI83428.1 - 0.12 12.0 0.4 0.28 10.8 0.4 1.6 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal AA_kinase PF00696.28 AFI83429.1 - 5.6e-48 163.6 1.7 1.8e-47 162.0 0.7 1.9 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 AFI83429.1 - 3.2e-19 68.6 0.0 6.8e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 AFI83429.1 - 0.055 13.3 0.1 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 PUA-like domain YqfQ PF14181.6 AFI83429.1 - 0.83 9.8 2.6 1.7 8.8 0.7 2.0 2 0 0 2 2 2 0 YqfQ-like protein Ribosomal_S20p PF01649.18 AFI83430.1 - 5.5e-25 87.8 12.8 6e-25 87.7 12.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 DUF612 PF04747.12 AFI83430.1 - 0.031 13.4 3.4 0.034 13.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 SMBP PF16785.5 AFI83430.1 - 0.054 13.7 5.5 0.05 13.8 4.7 1.4 1 1 0 1 1 1 0 Small metal-binding protein Exo_endo_phos PF03372.23 AFI83431.1 - 7.5e-21 74.7 0.0 9.6e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AFI83431.1 - 0.00034 20.4 0.1 0.00083 19.2 0.1 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RQC PF09382.10 AFI83433.1 - 2.6e-43 146.4 0.0 5.7e-43 145.3 0.0 1.6 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 AFI83433.1 - 4e-24 84.4 0.0 1.2e-23 82.8 0.0 1.9 1 0 0 1 1 1 1 HRDC domain HTH_40 PF14493.6 AFI83433.1 - 1e-22 80.4 0.1 8.4e-22 77.4 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain DEAD PF00270.29 AFI83433.1 - 7.8e-20 71.4 0.0 1.8e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI83433.1 - 1.1e-19 70.8 0.0 4.5e-14 52.7 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 AFI83433.1 - 5.2e-18 65.5 1.8 1.6e-17 64.0 1.8 1.9 1 0 0 1 1 1 1 RecQ zinc-binding Sigma70_r4_2 PF08281.12 AFI83433.1 - 0.0016 18.1 0.1 0.011 15.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 AFI83433.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DNA_pol_A_exoN PF18305.1 AFI83433.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Cys_Met_Meta_PP PF01053.20 AFI83433.1 - 0.07 11.6 0.1 0.52 8.8 0.0 2.2 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF2508 PF10704.9 AFI83433.1 - 0.09 13.0 3.0 2.2 8.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) SecA_DEAD PF07517.14 AFI83433.1 - 0.25 10.6 2.3 17 4.6 0.0 3.0 3 0 0 3 3 3 0 SecA DEAD-like domain STAC2_u1 PF16664.5 AFI83434.1 - 0.0057 17.1 1.8 0.0073 16.8 1.8 1.2 1 0 0 1 1 1 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 OATP PF03137.20 AFI83434.1 - 0.033 12.5 0.2 0.038 12.3 0.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family O-antigen_lig PF13425.6 AFI83434.1 - 0.044 12.6 1.3 0.043 12.6 1.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PCM1_C PF15717.5 AFI83434.1 - 0.061 12.0 8.6 0.074 11.7 8.6 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus U79_P34 PF03064.16 AFI83434.1 - 0.13 11.6 11.4 0.17 11.2 11.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 AFI83434.1 - 0.13 11.0 7.7 0.16 10.7 7.7 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 AFI83434.1 - 0.19 11.8 2.7 0.24 11.5 2.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Hid1 PF12722.7 AFI83434.1 - 0.23 9.5 4.8 0.27 9.3 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.6 AFI83434.1 - 0.29 9.8 6.3 0.33 9.6 6.3 1.0 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.10 AFI83434.1 - 0.92 8.8 17.9 1.1 8.6 17.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 AFI83434.1 - 0.94 8.6 10.2 1 8.5 10.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lipl32 PF12103.8 AFI83434.1 - 1.2 8.8 3.5 1.5 8.4 3.5 1.1 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order RR_TM4-6 PF06459.12 AFI83434.1 - 1.2 8.9 10.1 1.3 8.8 10.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 AFI83434.1 - 1.4 6.7 7.3 1.5 6.6 7.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 AFI83434.1 - 1.9 8.5 3.1 2.2 8.3 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Conotoxin PF02950.17 AFI83434.1 - 4.9 8.2 7.4 2.5e+02 2.8 7.4 2.7 1 1 0 1 1 1 0 Conotoxin CRA PF06589.11 AFI83434.1 - 6.5 6.9 11.8 16 5.6 11.8 1.7 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) SelP_N PF04592.14 AFI83434.1 - 7.4 5.9 16.9 9.5 5.5 16.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cupin_3 PF05899.12 AFI83435.1 - 2.5e-22 78.3 0.7 3.2e-22 78.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AFI83435.1 - 1.7e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AFI83435.1 - 0.005 16.4 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 AFI83435.1 - 0.0054 16.5 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 AFI83435.1 - 0.0085 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ HTH_3 PF01381.22 AFI83436.1 - 5.4e-15 55.2 0.1 7.4e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AFI83436.1 - 1.3e-09 38.3 0.2 1.6e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AFI83436.1 - 2.2e-07 31.2 0.0 3.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 AFI83436.1 - 2.1e-06 27.6 0.1 2.7e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AFI83436.1 - 0.00011 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AFI83436.1 - 0.00023 21.0 0.2 0.0003 20.7 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AFI83436.1 - 0.00027 20.4 0.3 0.00055 19.4 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AFI83436.1 - 0.00076 19.0 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_5 PF01022.20 AFI83436.1 - 0.0024 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_psq PF05225.16 AFI83436.1 - 0.0059 16.3 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_IclR PF09339.10 AFI83436.1 - 0.0064 16.3 0.3 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain CENP-B_N PF04218.13 AFI83436.1 - 0.0079 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain CUTL PF16557.5 AFI83436.1 - 0.0084 16.3 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 CUT1-like DNA-binding domain of SATB HNF-1_N PF04814.13 AFI83436.1 - 0.0095 16.6 0.0 0.01 16.5 0.0 1.1 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Sigma70_r4_2 PF08281.12 AFI83436.1 - 0.033 13.9 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.7 AFI83436.1 - 0.035 14.0 0.3 0.16 11.9 0.1 2.0 1 1 1 2 2 2 0 MarR family HTH_20 PF12840.7 AFI83436.1 - 0.049 13.7 0.4 0.3 11.2 0.1 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain PTA_PTB PF01515.19 AFI83436.1 - 0.049 12.9 0.3 0.061 12.6 0.2 1.3 1 1 1 2 2 2 0 Phosphate acetyl/butaryl transferase MarR PF01047.22 AFI83436.1 - 0.05 13.5 0.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 AFI83436.1 - 0.06 13.2 0.1 0.38 10.6 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 AFI83436.1 - 0.065 13.4 0.3 3.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AFI83436.1 - 0.068 13.1 0.2 0.49 10.3 0.2 2.0 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_AsnC-type PF13404.6 AFI83436.1 - 0.43 10.4 3.6 0.63 9.9 0.3 2.4 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain HigB-like_toxin PF05015.13 AFI83437.1 - 0.0031 17.9 0.0 0.0036 17.7 0.0 1.2 1 1 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB YoeB_toxin PF06769.14 AFI83437.1 - 0.017 15.1 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system ParE_toxin PF05016.15 AFI83437.1 - 0.02 15.5 0.2 0.038 14.6 0.2 1.6 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE YafQ_toxin PF15738.5 AFI83437.1 - 0.049 14.0 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ IMS PF00817.20 AFI83440.1 - 7.7e-51 172.0 0.0 1.5e-50 171.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AFI83440.1 - 3e-13 50.5 0.0 6.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AFI83440.1 - 1.2e-05 25.3 0.1 3.2e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 IMS family HHH motif MA3 PF02847.17 AFI83440.1 - 0.061 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 MA3 domain MFS_1 PF07690.16 AFI83442.1 - 3.3e-19 69.0 60.3 5e-12 45.4 26.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 AFI83442.1 - 9e-06 24.5 13.7 9e-06 24.5 13.7 2.7 2 1 0 2 2 2 1 Acetyl-coenzyme A transporter 1 Lumazine_bd_2 PF12893.7 AFI83444.1 - 2e-29 102.6 0.0 2.3e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding SnoaL_4 PF13577.6 AFI83444.1 - 0.026 14.6 0.1 0.044 13.9 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 AFI83444.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4878 PF12870.7 AFI83444.1 - 0.16 12.3 0.1 0.23 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) DUF3412 PF11892.8 AFI83445.1 - 9.6e-52 174.2 0.0 2.8e-51 172.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3412) DUF4478 PF14793.6 AFI83445.1 - 6.6e-42 141.8 0.2 1.2e-41 140.9 0.2 1.5 1 0 0 1 1 1 1 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Lysine_decarbox PF03641.14 AFI83445.1 - 1.3e-27 96.5 0.0 2.4e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AFI83445.1 - 8e-07 28.8 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 SLOG cluster4 family SSB PF00436.25 AFI83446.1 - 1.7e-39 134.0 1.0 2.1e-39 133.7 1.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MFS_1 PF07690.16 AFI83447.1 - 1.1e-45 156.1 53.2 1.4e-35 122.9 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AFI83447.1 - 9.4e-08 31.3 11.1 9.4e-08 31.3 11.1 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 AFI83447.1 - 0.054 11.9 26.0 0.01 14.2 3.9 2.1 1 1 1 2 2 2 0 Transmembrane secretion effector Gaa1 PF04114.14 AFI83447.1 - 3.5 6.5 12.6 0.28 10.1 7.3 1.7 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component UvrA_inter PF17760.1 AFI83448.1 - 6.9e-37 125.9 0.1 1.7e-36 124.6 0.1 1.7 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AFI83448.1 - 4.1e-34 117.3 0.0 6.7e-33 113.3 0.0 2.6 2 0 0 2 2 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AFI83448.1 - 7.2e-20 71.9 0.6 4.2e-09 37.0 0.2 4.5 3 2 0 3 3 3 3 ABC transporter AAA_29 PF13555.6 AFI83448.1 - 1.9e-08 33.9 0.2 0.00053 19.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 AFI83448.1 - 2.2e-08 33.8 0.0 0.17 11.3 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AFI83448.1 - 2.9e-07 31.0 0.2 0.047 14.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AFI83448.1 - 2.9e-06 27.9 0.2 0.014 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AFI83448.1 - 1.5e-05 25.3 0.1 0.11 12.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain DnaJ_CXXCXGXG PF00684.19 AFI83448.1 - 2e-05 24.8 1.9 0.094 13.1 0.2 3.5 3 0 0 3 3 3 1 DnaJ central domain AAA_18 PF13238.6 AFI83448.1 - 5.9e-05 23.6 0.2 1.7 9.2 0.1 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 AFI83448.1 - 8.2e-05 22.6 0.3 0.14 12.1 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 AFI83448.1 - 0.00035 20.8 0.0 0.95 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AFI83448.1 - 0.0011 18.7 0.1 0.072 12.8 0.1 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 AFI83448.1 - 0.0014 18.5 1.7 0.65 9.9 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 AFI83448.1 - 0.002 17.7 0.1 0.3 10.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AFI83448.1 - 0.0022 17.3 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AFI83448.1 - 0.0029 17.6 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 AFI83448.1 - 0.0043 16.7 2.4 0.23 11.0 1.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain BCA_ABC_TP_C PF12399.8 AFI83448.1 - 0.0076 16.1 1.6 2.7 8.0 0.4 2.7 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter AAA_14 PF13173.6 AFI83448.1 - 0.0082 16.2 0.0 15 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 AFI83448.1 - 0.0089 15.1 2.2 1.7 7.6 0.1 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_21 PF13304.6 AFI83448.1 - 0.017 15.0 7.2 0.44 10.3 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 AFI83448.1 - 0.024 14.4 2.6 2.4 7.8 0.1 3.5 4 0 0 4 4 3 0 AAA domain Zn-ribbon_8 PF09723.10 AFI83448.1 - 0.024 14.7 8.7 1 9.5 0.6 3.6 3 0 0 3 3 3 0 Zinc ribbon domain AAA_30 PF13604.6 AFI83448.1 - 0.033 13.9 0.7 8.1 6.1 0.3 3.2 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 AFI83448.1 - 0.047 13.6 0.1 14 5.6 0.1 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 AFI83448.1 - 0.048 13.0 0.1 10 5.3 0.0 2.5 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 AFI83448.1 - 0.057 13.5 1.4 2.5 8.2 0.1 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AFI83448.1 - 0.16 11.2 0.0 23 4.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 AFI83448.1 - 0.17 11.4 0.1 5 6.6 0.2 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 AFI83448.1 - 0.17 12.3 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 AFI83448.1 - 0.18 11.6 3.0 13 5.4 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 AFI83448.1 - 0.19 11.7 3.7 1.2 9.1 0.6 3.1 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 AFI83448.1 - 0.24 11.7 1.2 14 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 AFI83448.1 - 0.24 10.4 2.2 1.4 7.8 0.2 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CobU PF02283.16 AFI83448.1 - 0.26 10.8 0.6 40 3.7 0.1 3.1 3 0 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Anti-TRAP PF15777.5 AFI83448.1 - 0.46 10.5 5.4 5.7 7.0 0.3 3.5 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein CYTH PF01928.21 AFI83449.1 - 4.5e-20 72.3 0.5 5.1e-20 72.2 0.5 1.0 1 0 0 1 1 1 1 CYTH domain TonB_C PF03544.14 AFI83450.1 - 6.4e-14 52.1 0.0 2.5e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AFI83450.1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 TonB C terminal ApbE PF02424.15 AFI83451.1 - 1.1e-70 238.1 0.1 1.3e-70 237.9 0.1 1.0 1 0 0 1 1 1 1 ApbE family GSH-S_ATP PF02955.16 AFI83452.1 - 1.3e-80 268.9 0.0 1.8e-80 268.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AFI83452.1 - 6.8e-46 155.3 0.0 1.1e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AFI83452.1 - 3.8e-10 39.7 0.0 5.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AFI83452.1 - 2.5e-05 23.7 0.0 4.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AFI83452.1 - 0.0024 18.0 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Rimk_N PF18030.1 AFI83452.1 - 0.015 15.7 0.0 0.042 14.2 0.0 1.8 1 1 0 1 1 1 0 RimK PreATP-grasp domain ATPgrasp_ST PF14397.6 AFI83452.1 - 0.066 12.4 0.1 0.17 11.1 0.1 1.7 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp GpcrRhopsn4 PF10192.9 AFI83452.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain tRNA-synt_2e PF02091.15 AFI83453.1 - 3.4e-154 512.0 0.0 3.8e-154 511.8 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit tRNA_synt_2f PF02092.17 AFI83454.1 - 2.3e-214 713.2 0.0 3.1e-214 712.9 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 AFI83454.1 - 1.2e-10 41.6 0.4 2.8e-10 40.4 0.4 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Hydrolase_like PF13242.6 AFI83455.1 - 3e-13 49.6 0.1 5e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AFI83455.1 - 2.7e-09 37.4 0.0 5.4e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI83455.1 - 7.7e-08 32.9 0.0 1.6e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 AFI83455.1 - 9.1e-08 32.0 0.0 9.6e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_6 PF13344.6 AFI83455.1 - 2.4e-05 24.4 0.0 8.3e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AFI83455.1 - 0.0033 17.2 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI83455.1 - 0.0048 17.3 0.1 0.016 15.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 AFI83455.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) S6PP PF05116.13 AFI83455.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Acyltransferase PF01553.21 AFI83456.1 - 2.9e-22 78.8 0.0 4.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EAL PF00563.20 AFI83457.1 - 1.9e-56 191.3 1.2 3.3e-56 190.5 1.2 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI83457.1 - 2e-29 102.4 1.4 2e-29 102.4 1.4 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AFI83457.1 - 2.7e-08 34.0 0.3 2.4e-07 30.9 0.0 2.7 3 0 0 3 3 3 1 PAS domain Response_reg PF00072.24 AFI83457.1 - 4.9e-08 33.1 0.1 2.1e-07 31.1 0.1 2.1 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AFI83457.1 - 6.9e-08 32.5 0.0 3.8e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AFI83457.1 - 1.6e-06 28.0 0.2 1.2e-05 25.2 0.0 2.6 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.12 AFI83457.1 - 0.0022 18.3 0.0 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold AAA_16 PF13191.6 AFI83457.1 - 0.01 16.2 1.0 0.1 12.9 0.2 2.6 2 0 0 2 2 2 0 AAA ATPase domain GGDEF_2 PF17853.1 AFI83457.1 - 0.028 14.7 0.1 0.24 11.7 0.0 2.7 2 1 0 2 2 2 0 GGDEF-like domain Peptidase_M48 PF01435.18 AFI83458.1 - 2.9e-41 141.4 0.1 4.7e-41 140.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AFI83458.1 - 5.1e-05 22.6 0.0 0.00012 21.4 0.0 1.8 2 0 0 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.9 AFI83458.1 - 0.00041 20.2 0.0 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 SprT-like family DUF423 PF04241.15 AFI83458.1 - 0.0036 17.5 1.0 0.011 16.0 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Peptidase_M1 PF01433.20 AFI83458.1 - 0.0059 16.2 0.1 0.009 15.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain HisKA_7TM PF16927.5 AFI83458.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.8 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase Ldr_toxin PF13940.6 AFI83458.1 - 2.8 8.1 6.2 0.31 11.1 0.7 2.2 2 1 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system ATP-grasp_3 PF02655.14 AFI83459.1 - 6.5e-16 58.8 0.0 9.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AFI83459.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.6 AFI83459.1 - 0.0041 16.4 0.0 0.01 15.1 0.0 1.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_Ter PF15632.6 AFI83459.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 AFI83459.1 - 0.03 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DNA_pol3_delt_C PF14840.6 AFI83459.1 - 0.078 13.3 0.5 0.75 10.1 0.2 2.1 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term ATP-grasp PF02222.22 AFI83459.1 - 0.098 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 AFI83459.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Mpt_N PF09176.11 AFI83460.1 - 3.1e-37 126.6 0.1 7e-37 125.4 0.1 1.6 1 0 0 1 1 1 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal AlaDh_PNT_C PF01262.21 AFI83460.1 - 0.019 14.3 0.8 0.029 13.7 0.8 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 AFI83460.1 - 0.034 14.0 2.9 0.55 10.1 1.4 2.3 1 1 1 2 2 2 0 NAD(P)H-binding GHMP_kinases_C PF08544.13 AFI83461.1 - 1.2e-06 28.7 0.0 2.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AFI83461.1 - 9.1e-05 22.6 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain RNA_bind PF08675.11 AFI83461.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain Mpt_N PF09176.11 AFI83462.1 - 4.7e-31 106.7 1.3 9.6e-31 105.8 0.5 2.0 2 0 0 2 2 2 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Shikimate_DH PF01488.20 AFI83462.1 - 1.6e-07 31.5 0.1 2.6e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AFI83462.1 - 1e-05 25.9 0.1 1.7e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AFI83462.1 - 5.4e-05 23.5 0.1 0.00011 22.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AFI83462.1 - 0.00058 19.8 0.2 0.0013 18.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 AFI83462.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 AFI83462.1 - 0.0023 18.4 0.0 0.0058 17.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 AFI83462.1 - 0.0029 17.6 0.6 0.0039 17.1 0.1 1.5 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 AFI83462.1 - 0.0057 16.0 0.1 0.017 14.5 0.1 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 AFI83462.1 - 0.0069 15.9 0.2 0.013 15.0 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DAO PF01266.24 AFI83462.1 - 0.0076 15.9 0.2 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase adh_short_C2 PF13561.6 AFI83462.1 - 0.013 15.1 0.8 0.022 14.3 0.1 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Glu_dehyd_C PF16912.5 AFI83462.1 - 0.015 14.8 0.3 0.028 13.9 0.3 1.6 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus THF_DHG_CYH_C PF02882.19 AFI83462.1 - 0.019 14.3 0.4 0.064 12.6 0.2 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ELFV_dehydrog PF00208.21 AFI83462.1 - 0.031 14.0 1.4 0.042 13.6 0.1 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Staph_opine_DH PF10100.9 AFI83462.1 - 0.051 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase TrkA_N PF02254.18 AFI83462.1 - 0.052 13.8 0.5 0.098 12.9 0.1 1.8 2 0 0 2 2 1 0 TrkA-N domain Pyr_redox PF00070.27 AFI83462.1 - 0.11 13.0 1.2 0.28 11.8 0.1 2.3 3 1 0 3 3 1 0 Pyridine nucleotide-disulphide oxidoreductase CBM_15 PF03426.14 AFI83463.1 - 0.012 15.2 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) SoxY PF13501.6 AFI83465.1 - 1.4e-37 128.3 0.0 5.5e-36 123.2 0.0 2.2 2 1 0 2 2 2 1 Sulfur oxidation protein SoxY SoxZ PF08770.11 AFI83465.1 - 1.9e-25 88.5 0.1 3.3e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ ASH PF15780.5 AFI83465.1 - 0.017 15.3 0.0 20 5.4 0.0 3.3 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Desulfoferrodox PF01880.18 AFI83465.1 - 0.027 15.1 0.0 6 7.5 0.0 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin Lactamase_B PF00753.27 AFI83466.1 - 2.9e-18 66.6 0.9 4.3e-18 66.0 0.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AFI83466.1 - 0.015 14.8 0.5 0.098 12.2 0.1 2.0 1 1 1 2 2 2 0 Beta-lactamase superfamily domain tRNA-synt_1c PF00749.21 AFI83467.1 - 5.1e-109 364.0 0.0 6.4e-109 363.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PQQ PF01011.21 AFI83468.1 - 2.8e-27 93.3 14.1 1.1e-06 28.2 0.0 7.6 7 0 0 7 7 7 5 PQQ enzyme repeat PQQ_2 PF13360.6 AFI83468.1 - 6.8e-17 61.8 0.4 5.3e-09 36.0 0.0 2.9 3 0 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 AFI83468.1 - 4.2e-11 43.0 6.8 0.0069 16.9 0.2 6.0 5 0 0 5 5 5 4 PQQ-like domain SBP_bac_3 PF00497.20 AFI83469.1 - 2.9e-08 33.4 0.0 2.8e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 OpuAC PF04069.12 AFI83469.1 - 0.058 13.0 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system RNase_Zc3h12a PF11977.8 AFI83470.1 - 0.0049 16.7 0.2 0.0053 16.5 0.2 1.1 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF302 PF03625.14 AFI83470.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF302 HAMP PF00672.25 AFI83472.1 - 4.6e-12 46.1 1.6 2.1e-11 44.0 0.1 2.5 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 AFI83472.1 - 1.8e-09 37.5 0.1 6.9e-09 35.6 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 AFI83472.1 - 1.1e-07 32.4 0.1 3.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI83472.1 - 1.6e-05 24.7 0.6 0.0011 18.8 0.1 2.9 2 1 1 3 3 3 1 GHKL domain Raco_middle PF17651.1 AFI83472.1 - 0.014 15.1 0.1 25 4.5 0.0 3.4 3 0 0 3 3 3 0 RACo middle region HATPase_c_3 PF13589.6 AFI83472.1 - 0.015 15.1 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF43 PF01861.16 AFI83472.1 - 0.02 14.1 0.1 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain TBCC_N PF16752.5 AFI83472.1 - 0.031 14.7 1.5 3.8 8.0 0.0 2.8 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HATPase_c_2 PF13581.6 AFI83472.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain GLE1 PF07817.13 AFI83472.1 - 0.094 11.9 0.8 1.4 8.1 0.2 2.5 2 0 0 2 2 2 0 GLE1-like protein Sigma54_activat PF00158.26 AFI83473.1 - 1.9e-50 170.9 0.4 2.7e-50 170.4 0.4 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AFI83473.1 - 8.3e-26 90.4 0.1 2.3e-25 88.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AFI83473.1 - 9.2e-21 74.4 0.0 2.5e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AFI83473.1 - 8.4e-15 54.3 1.6 2e-14 53.1 1.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI83473.1 - 3.3e-07 30.4 0.2 1.1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AFI83473.1 - 3.3e-07 30.8 0.2 3.9e-06 27.3 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI83473.1 - 1e-05 25.0 0.3 0.00029 20.3 0.3 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AFI83473.1 - 8e-05 22.8 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AFI83473.1 - 0.00022 21.5 0.1 0.027 14.7 0.1 3.2 1 1 0 1 1 1 1 AAA domain HTH_30 PF13556.6 AFI83473.1 - 0.0017 18.1 0.1 0.0017 18.1 0.1 2.7 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain AAA_16 PF13191.6 AFI83473.1 - 0.0026 18.1 0.1 0.0059 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 AFI83473.1 - 0.035 13.5 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 AFI83473.1 - 0.049 13.0 0.1 0.69 9.2 0.0 2.8 2 1 1 3 3 3 0 KaiC HTH_1 PF00126.27 AFI83473.1 - 0.083 12.9 0.4 0.52 10.3 0.0 2.5 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family DNA_ligase_A_N PF04675.14 AFI83473.1 - 0.087 13.1 0.9 0.48 10.7 0.2 2.6 2 1 0 2 2 2 0 DNA ligase N terminus AAA_30 PF13604.6 AFI83473.1 - 0.096 12.4 0.1 0.28 10.9 0.0 1.7 1 1 1 2 2 2 0 AAA domain SspB PF04386.13 AFI83474.1 - 8.4e-32 110.3 0.0 1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Stringent starvation protein B GST_N_3 PF13417.6 AFI83475.1 - 3.3e-11 43.4 0.0 8.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AFI83475.1 - 2.3e-10 40.6 0.0 8.3e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AFI83475.1 - 3.7e-10 39.9 0.0 5.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AFI83475.1 - 2.4e-09 37.4 0.0 5.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AFI83475.1 - 1.4e-05 25.1 0.1 4.3e-05 23.5 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 AFI83475.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Cytochrom_C1 PF02167.15 AFI83476.1 - 9.4e-20 71.3 1.3 6.1e-18 65.4 1.3 2.5 1 1 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 AFI83476.1 - 0.0023 18.2 0.1 0.0052 17.1 0.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_B PF00033.19 AFI83477.1 - 7.4e-69 231.4 15.6 7.4e-69 231.4 15.6 1.9 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_C PF00032.17 AFI83477.1 - 1.8e-45 153.4 2.4 1.8e-45 153.4 2.4 3.9 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N_2 PF13631.6 AFI83477.1 - 8.5e-44 149.5 6.7 8.5e-44 149.5 6.7 2.3 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Rieske PF00355.26 AFI83478.1 - 2.9e-13 49.6 0.0 6.9e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.9 AFI83478.1 - 5.8e-09 35.2 1.7 9.7e-09 34.4 1.7 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Copper-bind PF00127.20 AFI83479.1 - 7.7e-11 42.3 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Zn-ribbon_8 PF09723.10 AFI83481.1 - 4.9e-18 65.0 0.5 4.9e-18 65.0 0.5 1.5 2 0 0 2 2 2 1 Zinc ribbon domain DUF1178 PF06676.11 AFI83481.1 - 0.00086 19.7 0.5 0.0013 19.2 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1178) HypA PF01155.19 AFI83481.1 - 0.0051 16.8 0.1 0.008 16.2 0.1 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 AFI83481.1 - 0.015 15.2 0.3 0.015 15.2 0.3 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Anti-TRAP PF15777.5 AFI83481.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.7 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein NOB1_Zn_bind PF08772.11 AFI83481.1 - 0.035 14.3 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Cys_rich_CPXG PF14255.6 AFI83481.1 - 0.045 13.7 2.2 0.11 12.4 2.2 1.7 1 1 0 1 1 1 0 Cysteine-rich CPXCG zinc_ribbon_4 PF13717.6 AFI83481.1 - 0.091 12.7 1.1 11 6.0 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.16 AFI83481.1 - 1.3 9.0 6.4 4.4 7.3 0.5 2.9 3 0 0 3 3 3 0 HIT zinc finger Rubredoxin_2 PF18073.1 AFI83481.1 - 2.5 7.9 7.2 3.2 7.6 0.3 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF502 PF04367.13 AFI83482.1 - 3.2e-37 126.7 1.2 3.7e-37 126.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF502) tRNA-synt_2 PF00152.20 AFI83483.1 - 3.7e-113 377.8 0.0 4.5e-113 377.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AFI83483.1 - 2.1e-29 101.6 0.0 3.8e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 AFI83483.1 - 1.4e-17 63.5 0.2 3.5e-17 62.2 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AFI83483.1 - 0.00012 21.7 0.1 0.17 11.3 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 AFI83483.1 - 0.044 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) NadA PF02445.16 AFI83484.1 - 2.2e-105 352.1 0.0 2.9e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Quinolinate synthetase A protein RRM_DME PF15628.6 AFI83484.1 - 0.16 12.1 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 RRM in Demeter zf-CHCC PF10276.9 AFI83485.1 - 1.5e-09 37.8 0.4 2.6e-09 37.0 0.4 1.5 1 1 0 1 1 1 1 Zinc-finger domain zinc_ribbon_9 PF14369.6 AFI83485.1 - 0.014 15.7 0.3 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon zf-RING_7 PF02591.15 AFI83485.1 - 0.025 14.7 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain NUDIX PF00293.28 AFI83486.1 - 7.3e-20 71.3 1.7 8.9e-20 71.1 1.7 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AFI83486.1 - 5.7e-19 68.1 0.4 6.5e-19 68.0 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain YacG PF03884.14 AFI83487.1 - 3.8e-23 81.0 4.3 4.4e-23 80.8 4.3 1.0 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG Lar_restr_allev PF14354.6 AFI83487.1 - 0.0071 16.7 0.9 0.0075 16.6 0.9 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Vhr1 PF04001.13 AFI83487.1 - 0.035 14.4 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Vhr1 OrfB_Zn_ribbon PF07282.11 AFI83487.1 - 0.083 12.8 1.9 0.11 12.4 1.9 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 AFI83487.1 - 0.16 12.0 0.9 0.17 11.9 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sgf11 PF08209.11 AFI83487.1 - 0.27 10.8 0.3 0.27 10.8 0.3 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF2310 PF10071.9 AFI83487.1 - 6.1 6.0 5.6 7.8 5.7 5.6 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) ZapD PF07072.11 AFI83488.1 - 2e-77 259.7 0.2 2.3e-77 259.5 0.2 1.0 1 0 0 1 1 1 1 Cell division protein FUSC PF04632.12 AFI83488.1 - 0.02 13.5 1.6 0.032 12.8 1.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family GABP-alpha PF11620.8 AFI83488.1 - 0.025 14.8 0.2 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF2785 PF10978.8 AFI83488.1 - 0.097 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) GvpG PF05120.12 AFI83488.1 - 0.51 10.4 4.0 12 6.0 0.5 2.4 1 1 1 2 2 2 0 Gas vesicle protein G CoaE PF01121.20 AFI83489.1 - 3.1e-64 215.9 1.2 3.6e-64 215.7 1.2 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 AFI83489.1 - 0.00058 20.0 0.4 0.0036 17.5 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AFI83489.1 - 0.029 14.9 0.6 0.16 12.5 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AFI83489.1 - 0.03 14.8 1.0 0.23 11.9 0.4 2.6 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 AFI83489.1 - 0.13 12.5 4.1 0.18 12.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 AFI83489.1 - 0.19 11.8 2.5 2.1 8.4 2.4 2.2 1 1 0 1 1 1 0 Shikimate kinase DiS_P_DiS PF06750.13 AFI83490.1 - 4.7e-35 119.6 0.4 9e-35 118.7 0.4 1.5 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 AFI83490.1 - 7.6e-25 87.4 13.0 7.6e-25 87.4 13.0 2.4 2 1 1 3 3 3 1 Type IV leader peptidase family DZR PF12773.7 AFI83490.1 - 0.051 13.6 0.8 0.092 12.8 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 AFI83490.1 - 0.06 12.8 1.6 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AFI83490.1 - 0.23 11.4 2.2 0.75 9.8 0.3 2.2 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 AFI83490.1 - 0.74 9.6 3.3 1.7 8.5 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AFI83490.1 - 4.9 7.2 5.7 17 5.5 5.7 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ogr_Delta PF04606.12 AFI83490.1 - 4.9 7.2 5.2 1.4 9.0 0.7 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger UPF0547 PF10571.9 AFI83490.1 - 5.9 7.1 8.6 4.5 7.5 1.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Rubredoxin_2 PF18073.1 AFI83490.1 - 6.5 6.6 5.8 17 5.3 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain GNVR PF13807.6 AFI83490.1 - 7.5 6.6 7.1 0.61 10.1 0.4 2.5 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase T2SSF PF00482.23 AFI83491.1 - 2.3e-63 211.8 10.1 1.3e-31 109.2 2.5 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F Goodbye PF17109.5 AFI83491.1 - 0.084 13.3 0.5 7 7.1 0.1 3.0 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF4190 PF13828.6 AFI83491.1 - 0.42 10.4 0.0 0.42 10.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) DUF2207 PF09972.9 AFI83491.1 - 0.65 8.7 2.5 0.32 9.7 0.5 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.12 AFI83491.1 - 6.5 6.7 8.1 0.35 10.8 1.0 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC T2SSE PF00437.20 AFI83492.1 - 7.3e-87 290.9 0.3 1.1e-86 290.4 0.3 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AFI83492.1 - 3.3e-17 62.7 1.2 1.1e-16 61.0 1.2 2.0 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_30 PF13604.6 AFI83492.1 - 0.0012 18.6 0.1 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AFI83492.1 - 0.0055 17.0 0.3 0.032 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 AFI83492.1 - 0.0065 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 AFI83492.1 - 0.0079 16.6 1.7 0.015 15.7 0.0 2.3 2 2 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 AFI83492.1 - 0.052 13.3 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 AFI83492.1 - 0.089 12.6 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AFI83492.1 - 0.16 12.0 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain LPAM_2 PF13627.6 AFI83493.1 - 1.2e-08 34.6 2.1 1.4e-08 34.3 2.1 1.1 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site Orn_Arg_deC_N PF02784.16 AFI83494.1 - 4.1e-74 249.1 0.0 1.8e-73 247.0 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AFI83494.1 - 2.8e-27 94.8 0.0 4.4e-27 94.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AFI83494.1 - 4.1e-07 29.9 0.0 1.1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DUF1955 PF09205.10 AFI83494.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) HTH_IclR PF09339.10 AFI83494.1 - 0.17 11.7 1.9 8.6 6.2 0.2 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain DAP_epimerase PF01678.19 AFI83495.1 - 2.8e-65 218.0 0.2 6.7e-33 113.4 0.1 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase DUF484 PF04340.12 AFI83496.1 - 2.4e-55 187.7 4.0 2.8e-55 187.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 GAF PF01590.26 AFI83496.1 - 0.0079 16.8 0.2 0.022 15.4 0.0 1.8 2 0 0 2 2 2 1 GAF domain Fmp27_WPPW PF10359.9 AFI83496.1 - 0.023 13.6 2.0 0.027 13.3 2.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1826 PF08856.11 AFI83496.1 - 0.058 13.3 2.7 0.061 13.2 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) Exonuc_VII_L PF02601.15 AFI83496.1 - 0.1 12.1 1.2 0.12 11.9 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMU163 PF17119.5 AFI83496.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis OmpH PF03938.14 AFI83496.1 - 0.73 10.2 4.7 1.7 9.0 4.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TEX13 PF15186.6 AFI83496.1 - 1.5 8.5 8.0 2.5 7.8 8.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family 7tm_7 PF08395.12 AFI83496.1 - 5 6.2 6.7 6.8 5.8 6.7 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Phage_integrase PF00589.22 AFI83497.1 - 1e-46 158.8 0.5 2.3e-45 154.5 0.0 2.1 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AFI83497.1 - 7.5e-26 90.3 2.5 2.2e-25 88.7 0.4 2.4 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AFI83497.1 - 1.6e-10 41.3 0.2 4.5e-10 39.9 0.2 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AFI83497.1 - 0.00037 20.8 0.0 0.00091 19.5 0.0 1.6 1 0 0 1 1 1 1 Phage integrase SAM-like domain DUF3435 PF11917.8 AFI83497.1 - 0.0014 17.6 0.4 0.0024 16.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MdcG PF10620.9 AFI83497.1 - 0.012 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Phage_int_SAM_2 PF12834.7 AFI83497.1 - 0.012 16.2 0.1 0.081 13.6 0.0 2.3 3 0 0 3 3 3 0 Phage integrase, N-terminal PAS_5 PF07310.13 AFI83497.1 - 0.023 14.5 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Integrase_1 PF12835.7 AFI83497.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Integrase Na_Ca_ex PF01699.24 AFI83498.1 - 1.6e-30 106.1 31.0 2.7e-15 56.7 14.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PPE PF00823.19 AFI83498.1 - 0.056 13.5 0.5 0.17 11.9 0.2 1.9 2 0 0 2 2 2 0 PPE family Transposase_20 PF02371.16 AFI83499.1 - 1.3e-18 67.1 0.1 3.8e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AFI83499.1 - 0.053 13.4 1.7 0.065 13.1 0.4 1.8 2 0 0 2 2 2 0 Transposase DUF4485 PF14846.6 AFI83499.1 - 0.095 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) FAD_binding_7 PF03441.14 AFI83500.1 - 4.2e-80 268.0 1.1 1.8e-79 265.9 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AFI83500.1 - 9.4e-39 133.0 1.2 1.6e-38 132.3 1.2 1.3 1 0 0 1 1 1 1 DNA photolyase DPRP PF04244.13 AFI83501.1 - 1.5e-68 231.0 0.3 2.6e-68 230.2 0.3 1.4 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein DUF3429 PF11911.8 AFI83502.1 - 3.2e-19 69.7 20.8 3.5e-19 69.5 20.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) RNase_T PF00929.24 AFI83503.1 - 3e-36 125.5 0.0 5.9e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease GIY-YIG PF01541.24 AFI83503.1 - 8.8e-09 35.5 0.0 2.4e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain DDE_Tnp_1_3 PF13612.6 AFI83504.1 - 2e-74 248.8 0.2 2.6e-74 248.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI83504.1 - 1.2e-21 77.4 0.9 6.7e-20 71.7 0.9 2.1 1 1 0 1 1 1 1 Transposase DDE domain RNase_T PF00929.24 AFI83505.1 - 5e-33 115.0 0.0 5.7e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF1380 PF07128.12 AFI83505.1 - 0.16 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Peptidase_M48_N PF16491.5 AFI83506.1 - 9.4e-55 185.3 1.8 9.4e-55 185.3 1.8 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 AFI83506.1 - 1.4e-43 149.0 0.0 2.1e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AFI83506.1 - 1.3e-08 34.5 0.4 1.6e-07 30.9 0.0 2.7 3 0 0 3 3 3 1 BlaR1 peptidase M56 DUF2268 PF10026.9 AFI83506.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 AFI83506.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family GGDEF PF00990.21 AFI83508.1 - 9.6e-38 129.5 0.3 9.6e-38 129.5 0.3 1.7 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain BRE1 PF08647.11 AFI83508.1 - 0.32 11.1 6.6 3.7 7.7 1.1 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 AFI83508.1 - 0.36 9.7 8.5 0.58 9.0 8.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tektin PF03148.14 AFI83508.1 - 0.59 8.8 9.4 1.1 8.0 9.4 1.4 1 0 0 1 1 1 0 Tektin family DASH_Dad4 PF08650.10 AFI83508.1 - 1.6 8.8 5.1 1.1 9.3 0.2 3.1 3 1 1 4 4 4 0 DASH complex subunit Dad4 PRKG1_interact PF15898.5 AFI83508.1 - 3.9 8.4 9.6 2.9 8.8 1.3 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 AFI83508.1 - 5.2 7.1 13.2 2.3 8.3 3.7 2.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 AFI83508.1 - 8.3 6.9 12.5 41 4.7 12.5 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region MFS_1 PF07690.16 AFI83509.1 - 1.4e-20 73.6 43.0 2e-20 73.1 43.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 AFI83509.1 - 2.1e-05 23.1 15.4 0.00016 20.2 1.2 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Rer1 PF03248.13 AFI83509.1 - 0.0077 16.0 0.3 0.029 14.1 0.3 2.0 1 0 0 1 1 1 1 Rer1 family Kinocilin PF15033.6 AFI83509.1 - 1.2 8.8 4.4 3.3 7.4 4.4 1.8 1 0 0 1 1 1 0 Kinocilin protein Usp PF00582.26 AFI83510.1 - 5.8e-30 104.6 0.0 7e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family IF3_N PF05198.16 AFI83510.1 - 0.045 14.0 0.0 3.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Pyr_redox_2 PF07992.14 AFI83511.1 - 2.7e-51 174.6 1.0 3.1e-51 174.4 1.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AFI83511.1 - 2.4e-20 73.0 1.0 4.3e-17 62.3 0.1 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI83511.1 - 1.7e-19 70.2 2.3 2e-18 66.7 0.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AFI83511.1 - 1.2e-07 31.6 6.6 0.23 11.0 0.0 4.1 2 2 2 4 4 4 4 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AFI83511.1 - 3.4e-06 26.4 7.3 0.035 13.2 0.6 4.3 2 2 3 5 5 5 2 FAD binding domain FAD_oxidored PF12831.7 AFI83511.1 - 2.3e-05 24.0 0.5 0.0014 18.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 AFI83511.1 - 0.0005 19.3 3.7 0.17 10.9 0.2 3.9 3 1 0 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.14 AFI83511.1 - 0.0017 17.1 3.8 2.6 6.7 0.1 4.0 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.6 AFI83511.1 - 0.0037 17.7 0.0 0.033 14.6 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 AFI83511.1 - 0.0053 16.0 0.1 0.29 10.2 0.0 2.4 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AFI83511.1 - 0.028 14.6 0.1 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AFI83511.1 - 0.031 13.5 0.5 2.7 7.2 0.1 2.7 2 1 1 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 AFI83511.1 - 0.054 12.3 0.4 0.37 9.6 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 AFI83511.1 - 0.06 13.4 0.0 2.1 8.4 0.0 3.1 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 AFI83511.1 - 0.12 11.7 0.7 8.6 5.6 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AFI83511.1 - 0.16 11.2 4.4 9 5.4 0.2 3.7 2 2 2 4 4 4 0 FAD binding domain FtsK_SpoIIIE PF01580.18 AFI83512.1 - 7.3e-69 231.8 0.7 5.7e-68 228.9 0.7 2.1 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_4TM PF13491.6 AFI83512.1 - 1.1e-40 139.1 19.3 1.7e-40 138.5 19.3 1.3 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE FtsK_alpha PF17854.1 AFI83512.1 - 7.1e-30 103.1 0.1 1.8e-29 101.8 0.1 1.7 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 AFI83512.1 - 6.8e-27 93.1 1.5 9.4e-27 92.6 0.4 1.9 2 0 0 2 2 2 1 Ftsk gamma domain AAA_10 PF12846.7 AFI83512.1 - 2.6e-07 29.9 0.0 0.0023 16.9 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 AFI83512.1 - 0.00015 21.9 0.1 0.00015 21.9 0.1 1.7 2 0 0 2 2 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AFI83512.1 - 0.00083 18.4 0.1 0.0083 15.1 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 AFI83512.1 - 0.0016 18.7 0.1 0.037 14.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI83512.1 - 0.0022 17.1 0.0 0.0062 15.6 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 AFI83512.1 - 0.0061 16.3 0.3 0.022 14.5 0.3 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase TniB PF05621.11 AFI83512.1 - 0.016 14.6 0.1 3.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 AFI83512.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_3 PF07859.13 AFI83512.1 - 0.083 12.7 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Cupin_4 PF08007.12 AFI83512.1 - 0.11 11.9 0.7 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 Cupin superfamily protein DUF815 PF05673.13 AFI83512.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) LolA PF03548.15 AFI83513.1 - 1.1e-49 168.4 0.5 1.2e-49 168.1 0.5 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 AFI83513.1 - 6.6e-07 28.9 0.1 0.018 14.4 0.0 2.1 2 0 0 2 2 2 2 Predicted periplasmic protein (DUF2092) MgsA_C PF12002.8 AFI83514.1 - 2.9e-65 219.3 0.1 5.6e-65 218.3 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AFI83514.1 - 1e-23 83.4 0.5 2.6e-23 82.1 0.5 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 AFI83514.1 - 2.9e-16 60.1 0.0 7.6e-16 58.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AFI83514.1 - 3.6e-14 52.8 0.0 1.3e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AFI83514.1 - 6.8e-07 29.8 0.6 0.00067 20.1 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 AFI83514.1 - 5.2e-06 26.0 0.1 0.00066 19.1 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AFI83514.1 - 1.3e-05 25.0 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 AFI83514.1 - 1.9e-05 24.7 0.2 0.004 17.2 0.1 2.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AFI83514.1 - 9.1e-05 22.7 0.2 0.0083 16.4 0.3 3.2 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 AFI83514.1 - 0.00015 21.8 0.1 0.2 11.7 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AFI83514.1 - 0.00053 19.8 0.3 0.0036 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AFI83514.1 - 0.00054 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AFI83514.1 - 0.0019 18.2 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AFI83514.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase_C PF13335.6 AFI83514.1 - 0.0053 17.4 1.1 4.2 8.1 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_19 PF13245.6 AFI83514.1 - 0.0055 17.1 0.1 0.53 10.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 AFI83514.1 - 0.012 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AFI83514.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 AFI83514.1 - 0.025 15.0 0.0 0.053 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AFI83514.1 - 0.026 13.9 0.1 9.9 5.5 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein AAA_2 PF07724.14 AFI83514.1 - 0.03 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 AFI83514.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AFI83514.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFI83514.1 - 0.035 14.7 0.0 0.091 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AFI83514.1 - 0.038 14.5 0.0 0.061 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 AFI83514.1 - 0.057 13.3 0.0 8.2 6.3 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 AFI83514.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 AFI83514.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 AFI83514.1 - 0.12 11.6 0.0 1.3 8.2 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SAM_MT PF04445.13 AFI83515.1 - 1.4e-93 312.6 0.1 1.6e-93 312.4 0.1 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Cons_hypoth95 PF03602.15 AFI83515.1 - 0.00021 21.0 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 AFI83515.1 - 0.0099 16.6 0.2 0.026 15.2 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83515.1 - 0.022 14.5 0.0 0.05 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 AFI83515.1 - 0.032 14.1 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 AFI83515.1 - 0.064 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 AFI83515.1 - 0.13 13.3 0.0 0.22 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lactonase PF10282.9 AFI83516.1 - 2.1e-22 79.9 4.5 4.2e-08 32.8 0.1 3.9 1 1 1 3 3 3 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AFI83516.1 - 8.9e-18 64.0 4.7 6.7e-08 31.5 0.3 3.0 1 1 1 3 3 3 3 Cytochrome D1 heme domain SGL PF08450.12 AFI83516.1 - 1.9e-10 40.8 4.2 0.0016 18.0 0.6 3.4 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF4221 PF13970.6 AFI83516.1 - 1.7e-09 37.7 2.3 0.0026 17.4 0.1 4.9 1 1 4 5 5 5 3 Domain of unknown function (DUF4221) Arylesterase PF01731.20 AFI83516.1 - 7.2e-09 35.7 3.0 0.28 11.4 0.1 5.4 2 2 3 5 5 5 2 Arylesterase NHL PF01436.21 AFI83516.1 - 2e-07 30.7 2.3 1.1 9.4 0.0 5.1 5 0 0 5 5 5 2 NHL repeat ANAPC4_WD40 PF12894.7 AFI83516.1 - 5.1e-07 29.9 6.1 2.2 8.6 0.0 6.0 1 1 5 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Glu_cyclase_2 PF05096.12 AFI83516.1 - 7.1e-07 28.9 1.9 0.0041 16.6 0.2 3.2 1 1 1 2 2 2 2 Glutamine cyclotransferase ThaI PF15514.6 AFI83516.1 - 0.00033 20.4 1.0 0.038 13.6 0.0 3.2 3 1 1 4 4 4 1 Restriction endonuclease ThaI Me-amine-dh_H PF06433.11 AFI83516.1 - 0.0083 15.0 2.8 0.71 8.7 0.1 3.5 2 1 0 3 3 3 1 Methylamine dehydrogenase heavy chain (MADH) DUF5050 PF16472.5 AFI83516.1 - 0.011 15.0 0.9 0.03 13.6 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5050) DUF3261 PF11659.8 AFI83516.1 - 0.017 15.0 0.0 0.28 11.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3261) Str_synth PF03088.16 AFI83516.1 - 0.033 14.3 0.2 4 7.6 0.0 3.5 3 0 0 3 3 3 0 Strictosidine synthase PPC PF04151.15 AFI83516.1 - 0.042 15.0 0.5 0.17 13.0 0.5 2.1 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain UPF0262 PF06793.12 AFI83516.1 - 0.065 13.3 0.2 1.9 8.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0262) DUF1513 PF07433.11 AFI83516.1 - 0.079 12.0 0.1 13 4.7 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) CN_hydrolase PF00795.22 AFI83516.1 - 0.085 12.2 0.3 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Carbon-nitrogen hydrolase ZFYVE21_C PF16696.5 AFI83516.1 - 0.11 12.4 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus Polyketide_cyc2 PF10604.9 AFI83517.1 - 5.1e-26 91.7 0.3 4.4e-25 88.6 0.3 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 AFI83517.1 - 0.0012 18.6 0.1 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 Carbon monoxide dehydrogenase subunit G (CoxG) AHSA1 PF08327.11 AFI83517.1 - 0.013 15.7 0.2 0.024 14.8 0.2 1.6 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 AFI83517.1 - 0.014 15.6 0.1 0.017 15.3 0.1 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABC_tran PF00005.27 AFI83518.1 - 7.1e-29 101.1 0.0 1.2e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 AFI83518.1 - 0.00012 22.1 0.2 0.00025 21.0 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AFI83518.1 - 0.00024 21.4 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AFI83518.1 - 0.00033 20.3 0.4 0.15 11.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AFI83518.1 - 0.0007 19.3 0.3 0.0014 18.3 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI83518.1 - 0.0016 18.8 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AFI83518.1 - 0.0017 18.9 0.3 0.0027 18.3 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AFI83518.1 - 0.0018 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AFI83518.1 - 0.0077 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AFI83518.1 - 0.011 15.1 0.1 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 KaiC ABC_ATPase PF09818.9 AFI83518.1 - 0.013 14.4 3.1 1.7 7.4 0.7 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 AFI83518.1 - 0.015 15.1 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 AFI83518.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 AFI83518.1 - 0.032 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 AFI83518.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_28 PF13521.6 AFI83518.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFI83518.1 - 0.17 12.4 0.1 0.33 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AFI83518.1 - 0.17 12.2 1.2 0.22 11.9 0.9 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AFI83518.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 AFI83518.1 - 0.22 10.2 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase MlaE PF02405.16 AFI83519.1 - 1.6e-75 253.5 13.6 1.9e-75 253.2 13.6 1.1 1 0 0 1 1 1 1 Permease MlaE MlaD PF02470.20 AFI83520.1 - 7.2e-26 90.3 0.1 9.6e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 MlaD protein MlaC PF05494.12 AFI83521.1 - 1.4e-56 190.8 0.1 2.1e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 MlaC protein STAS_2 PF13466.6 AFI83522.1 - 7.8e-14 51.8 0.0 9.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AFI83522.1 - 0.028 14.0 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 STAS domain BolA PF01722.18 AFI83523.1 - 1.3e-13 51.0 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein EPSP_synthase PF00275.20 AFI83524.1 - 2.7e-117 392.0 4.7 3.1e-117 391.8 4.7 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Ribosomal_L12 PF00542.19 AFI83524.1 - 1.2 9.6 3.6 12 6.3 0.1 3.7 3 1 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain HisG PF01634.18 AFI83525.1 - 1.9e-48 164.5 0.1 2.3e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Histidinol_dh PF00815.20 AFI83526.1 - 2e-171 570.5 2.4 2.4e-171 570.3 2.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase UCMA PF17085.5 AFI83526.1 - 0.02 14.9 0.3 0.041 13.9 0.3 1.5 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Retrotrans_gag PF03732.17 AFI83526.1 - 0.055 13.7 0.4 0.18 12.1 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein Aminotran_1_2 PF00155.21 AFI83527.1 - 6.1e-54 183.6 0.0 6.9e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4124 PF13511.6 AFI83528.1 - 2.1e-08 34.3 0.0 5.6e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) UPF0242 PF06785.11 AFI83528.1 - 0.072 13.2 21.9 0.12 12.5 21.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMEM208_SND2 PF05620.11 AFI83528.1 - 0.75 9.6 0.0 0.75 9.6 0.0 2.4 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF4407 PF14362.6 AFI83528.1 - 1.5 8.1 23.5 3.1 7.0 23.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.6 AFI83528.1 - 3.5 7.8 27.7 0.046 13.9 4.3 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit XhlA PF10779.9 AFI83528.1 - 3.8 7.8 6.6 13 6.1 0.7 2.8 1 1 1 2 2 2 0 Haemolysin XhlA Exonuc_VII_L PF02601.15 AFI83528.1 - 7.5 6.0 21.2 17 4.9 20.6 1.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF3087 PF11286.8 AFI83528.1 - 7.8 5.9 9.7 0.88 9.0 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) TauE PF01925.19 AFI83529.1 - 1.2e-34 119.9 37.7 1.5e-34 119.7 37.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Pribosyltran PF00156.27 AFI83530.1 - 3.5e-14 52.6 0.1 4.6e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PA PF02225.22 AFI83530.1 - 0.00024 21.1 0.1 0.00036 20.5 0.1 1.3 1 0 0 1 1 1 1 PA domain DHBP_synthase PF00926.19 AFI83530.1 - 0.0037 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase UPRTase PF14681.6 AFI83530.1 - 0.13 11.7 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase MetW PF07021.12 AFI83531.1 - 4.8e-77 257.9 0.0 5.4e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 AFI83531.1 - 5.7e-14 52.5 0.0 1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83531.1 - 8.7e-12 45.2 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83531.1 - 2.6e-10 40.3 0.2 6.2e-10 39.1 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83531.1 - 3.7e-10 40.4 0.0 6.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83531.1 - 7.1e-10 39.5 0.0 1.3e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 AFI83531.1 - 0.0018 18.6 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_18 PF12847.7 AFI83531.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AFI83531.1 - 0.019 14.6 0.1 0.042 13.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 AFI83531.1 - 0.028 14.3 0.0 0.073 12.9 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase THB PF18362.1 AFI83531.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Tri-helix bundle domain Abhydrolase_1 PF00561.20 AFI83532.1 - 5.6e-36 124.5 0.0 7.4e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AFI83532.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 AFI83532.1 - 0.0097 16.5 0.1 0.012 16.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AFI83532.1 - 0.055 13.3 0.4 0.33 10.8 0.0 2.2 3 0 0 3 3 3 0 Serine hydrolase Hydrolase_4 PF12146.8 AFI83532.1 - 0.11 11.8 0.1 0.31 10.3 0.1 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 YGGT PF02325.17 AFI83533.1 - 2.6e-30 104.6 19.2 3.7e-17 62.5 5.2 2.2 2 0 0 2 2 2 2 YGGT family P5CR_dimer PF14748.6 AFI83534.1 - 7.4e-36 122.5 1.2 1.5e-35 121.5 1.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AFI83534.1 - 2.2e-23 82.7 0.3 5e-23 81.5 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AFI83534.1 - 6.8e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AFI83534.1 - 8.7e-06 25.8 0.7 1.5e-05 25.0 0.5 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AFI83534.1 - 0.00014 22.7 0.2 0.00081 20.2 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 AFI83534.1 - 0.00028 20.9 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AFI83534.1 - 0.00041 20.0 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PDH PF02153.17 AFI83534.1 - 0.0036 16.3 0.4 0.012 14.6 0.4 1.8 1 1 0 1 1 1 1 Prephenate dehydrogenase OCD_Mu_crystall PF02423.15 AFI83534.1 - 0.01 14.8 0.3 0.024 13.6 0.1 1.7 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 AFI83534.1 - 0.022 15.0 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 AFI83534.1 - 0.037 14.4 0.1 0.088 13.2 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_7 PF13241.6 AFI83534.1 - 0.043 14.2 0.0 0.25 11.8 0.0 2.1 2 1 1 3 3 3 0 Putative NAD(P)-binding Ala_racemase_N PF01168.20 AFI83535.1 - 3.3e-30 105.4 0.2 4e-30 105.1 0.2 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain T2SSE PF00437.20 AFI83536.1 - 1.2e-47 162.3 0.4 2.2e-47 161.4 0.4 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 AFI83536.1 - 5.8e-05 22.6 0.1 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AFI83536.1 - 0.00011 22.5 0.1 0.00031 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI83536.1 - 0.00011 21.9 0.1 0.00022 20.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI83536.1 - 0.00013 22.4 0.0 0.00021 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AFI83536.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DAP3 PF10236.9 AFI83536.1 - 0.00019 20.7 0.0 0.00072 18.8 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ResIII PF04851.15 AFI83536.1 - 0.00039 20.5 0.0 0.00077 19.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 AFI83536.1 - 0.00043 20.9 0.2 0.001 19.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AFI83536.1 - 0.00086 19.1 0.0 0.0051 16.6 0.0 2.2 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 AFI83536.1 - 0.0013 19.3 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TK PF00265.18 AFI83536.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 AFI83536.1 - 0.0033 17.4 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AFI83536.1 - 0.0038 17.6 0.2 0.01 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 AFI83536.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain SRP54 PF00448.22 AFI83536.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 AFI83536.1 - 0.015 15.1 0.0 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 AFI83536.1 - 0.017 15.0 0.0 0.072 13.0 0.0 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 AFI83536.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 AFI83536.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 AFI83536.1 - 0.024 14.1 0.0 0.19 11.2 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein cobW PF02492.19 AFI83536.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AFI83536.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.29 AFI83536.1 - 0.055 13.9 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AFI83536.1 - 0.062 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AFI83536.1 - 0.076 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 AFI83536.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 AFI83536.1 - 0.11 12.5 0.4 1 9.3 0.2 2.3 1 1 1 2 2 2 0 NTPase Sigma54_activat PF00158.26 AFI83536.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DEAD PF00270.29 AFI83536.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.9 AFI83536.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 AFI83537.1 - 5.7e-38 130.5 1.0 8e-38 130.1 1.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AFI83537.1 - 6.1e-05 23.6 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AFI83537.1 - 0.0017 17.8 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 AFI83537.1 - 0.0017 17.9 0.2 0.0053 16.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_29 PF13555.6 AFI83537.1 - 0.0025 17.5 0.4 0.0055 16.4 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AFI83537.1 - 0.0061 17.1 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AFI83537.1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AFI83537.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 AFI83537.1 - 0.016 14.8 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 AFI83537.1 - 0.019 15.1 0.2 0.033 14.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AFI83537.1 - 0.02 14.1 0.2 0.19 10.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 AFI83537.1 - 0.064 13.3 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AFI83537.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 AFI83537.1 - 0.1 11.5 0.2 0.21 10.4 0.2 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain OmpA PF00691.20 AFI83538.1 - 1.1e-26 93.1 0.1 1.5e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 OmpA family TSP_3 PF02412.18 AFI83538.1 - 0.0012 18.5 18.4 0.0039 16.8 3.1 2.8 3 0 0 3 3 3 2 Thrombospondin type 3 repeat Bacteriocin_IIc PF10439.9 AFI83538.1 - 0.023 14.8 16.6 0.06 13.5 16.6 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Antistasin PF02822.14 AFI83538.1 - 0.14 12.8 3.3 20 5.9 0.2 3.5 3 0 0 3 3 3 0 Antistasin family Gly-zipper_OmpA PF13436.6 AFI83538.1 - 0.31 10.9 26.3 0.83 9.5 26.3 1.7 1 0 0 1 1 1 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 AFI83538.1 - 1.1 9.0 28.3 0.31 10.8 24.9 1.8 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 AFI83538.1 - 1.6 8.7 26.6 3.6 7.5 26.6 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF3482 PF11981.8 AFI83538.1 - 1.7 8.0 7.9 3.4 7.0 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_Omp PF13488.6 AFI83538.1 - 2.4 8.2 27.9 6.1 6.9 27.9 1.7 1 0 0 1 1 1 0 Glycine zipper TraT PF05818.12 AFI83538.1 - 2.7 7.6 5.4 4.6 6.9 5.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein CsbD PF05532.12 AFI83539.1 - 6.4e-19 67.6 2.5 7.2e-19 67.4 2.5 1.0 1 0 0 1 1 1 1 CsbD-like PqqD PF05402.12 AFI83539.1 - 0.093 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) BON PF04972.17 AFI83540.1 - 4.3e-34 116.6 9.7 2.3e-17 63.1 0.7 2.1 2 0 0 2 2 2 2 BON domain SBD PF17882.1 AFI83540.1 - 0.025 14.4 3.4 0.1 12.4 3.1 2.1 1 1 0 1 1 1 0 OAA-family lectin sugar binding domain DUF4015 PF13200.6 AFI83540.1 - 0.044 12.8 2.5 0.19 10.7 0.3 2.0 2 0 0 2 2 2 0 Putative glycosyl hydrolase domain DUF2383 PF09537.10 AFI83541.1 - 1.6e-05 25.2 0.1 2.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Sigma54_activat PF00158.26 AFI83542.1 - 2.7e-63 212.6 0.0 4.2e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AFI83542.1 - 1.6e-22 80.1 0.0 8.9e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AFI83542.1 - 2e-11 43.4 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI83542.1 - 8.8e-08 32.2 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AFI83542.1 - 2.2e-06 28.1 0.0 9.2e-06 26.1 0.0 2.1 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AFI83542.1 - 0.00024 21.3 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AFI83542.1 - 0.0012 18.3 0.0 0.047 13.1 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AFI83542.1 - 0.0021 18.4 0.0 0.0052 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain HTH_30 PF13556.6 AFI83542.1 - 0.01 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MCM PF00493.23 AFI83542.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 AFI83542.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_8 PF12780.7 AFI83542.1 - 0.03 13.6 0.1 0.063 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 HTH_Tnp_ISL3 PF13542.6 AFI83542.1 - 0.032 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 AAA_7 PF12775.7 AFI83542.1 - 0.055 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AFI83542.1 - 0.092 12.5 0.1 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein HTH_29 PF13551.6 AFI83542.1 - 0.094 12.8 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix ATP-synt_ab PF00006.25 AFI83542.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain HTH_23 PF13384.6 AFI83542.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HipA_C PF07804.12 AFI83543.1 - 2.5e-52 177.6 0.0 3.4e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 AFI83543.1 - 2.7e-25 88.9 0.0 6.1e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 HipA N-terminal domain HTH_3 PF01381.22 AFI83544.1 - 6.1e-12 45.4 0.1 1.2e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AFI83544.1 - 9.3e-09 35.5 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AFI83544.1 - 3.5e-08 33.3 0.0 7.7e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AFI83544.1 - 1.4e-05 24.9 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AFI83544.1 - 0.0022 18.4 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AFI83544.1 - 0.003 17.4 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AFI83544.1 - 0.021 14.3 0.3 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 MqsA_antitoxin PF15731.5 AFI83544.1 - 0.066 13.3 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA FliJ PF02050.16 AFI83546.1 - 7.8e-05 22.9 2.4 0.0001 22.5 2.4 1.2 1 0 0 1 1 1 1 Flagellar FliJ protein DUF3958 PF13125.6 AFI83546.1 - 0.011 15.9 5.3 0.04 14.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) CdvA PF18822.1 AFI83546.1 - 0.02 14.7 1.1 0.02 14.7 1.1 1.9 1 1 1 2 2 2 0 CdvA-like coiled-coil domain CHIP_TPR_N PF18391.1 AFI83546.1 - 0.028 15.2 4.8 0.097 13.5 2.8 2.1 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain KIP1 PF07765.12 AFI83546.1 - 0.041 14.0 3.7 0.061 13.5 3.2 1.6 1 1 0 1 1 1 0 KIP1-like protein REF PF05755.12 AFI83546.1 - 0.046 13.5 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Ribosomal_L18_c PF14204.6 AFI83546.1 - 0.065 14.2 3.3 0.13 13.2 2.2 1.9 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region ER PF01133.17 AFI83546.1 - 0.11 12.5 2.3 4.9 7.3 0.4 2.2 1 1 1 2 2 2 0 Enhancer of rudimentary PSI_PsaF PF02507.15 AFI83546.1 - 0.12 12.2 0.9 0.75 9.6 0.1 1.9 1 1 1 2 2 2 0 Photosystem I reaction centre subunit III FapA PF03961.13 AFI83546.1 - 0.13 10.9 3.7 0.14 10.7 3.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ribosomal_S20p PF01649.18 AFI83546.1 - 0.14 12.8 1.7 3.1 8.5 0.1 2.3 1 1 1 2 2 2 0 Ribosomal protein S20 DivIVA PF05103.13 AFI83546.1 - 0.15 12.2 0.7 0.15 12.2 0.7 2.0 1 1 0 2 2 2 0 DivIVA protein APG6_N PF17675.1 AFI83546.1 - 0.44 11.1 5.3 1.5 9.3 5.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region HTH_Tnp_1 PF01527.20 AFI83548.1 - 0.0053 17.0 0.3 0.0069 16.7 0.3 1.2 1 0 0 1 1 1 1 Transposase DUF4355 PF14265.6 AFI83548.1 - 0.0088 16.3 0.3 0.0092 16.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) rve PF00665.26 AFI83549.1 - 6.4e-18 65.1 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AFI83549.1 - 6.7e-12 45.4 6.6 1.4e-11 44.3 6.6 1.5 1 0 0 1 1 1 1 HTH-like domain SNARE_assoc PF09335.11 AFI83550.1 - 1.7e-21 76.9 3.8 1.7e-21 76.9 3.8 2.0 3 1 0 3 3 3 1 SNARE associated Golgi protein Epiglycanin_C PF14654.6 AFI83550.1 - 0.2 11.7 0.3 0.2 11.7 0.3 2.7 2 1 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF3099 PF11298.8 AFI83550.1 - 5.8 7.1 6.5 21 5.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Glycos_transf_1 PF00534.20 AFI83551.1 - 9.7e-40 135.9 0.7 1.1e-38 132.5 0.3 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI83551.1 - 1.6e-33 116.1 1.2 1.4e-32 113.0 0.1 2.6 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AFI83551.1 - 1.5e-28 99.9 0.0 6.6e-27 94.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AFI83551.1 - 2.4e-17 63.8 0.0 5.9e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AFI83551.1 - 4.2e-12 46.3 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 AFI83551.1 - 1.1e-08 35.3 0.0 3.3e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 AFI83551.1 - 0.00031 20.5 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain CompInhib_SCIN PF11546.8 AFI83551.1 - 0.057 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Response_reg PF00072.24 AFI83552.1 - 1.4e-28 99.3 0.0 2.5e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI83552.1 - 9.2e-14 51.3 0.1 3.3e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Cytochrome_B PF00033.19 AFI83552.1 - 0.064 13.1 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome b/b6/petB HATPase_c PF02518.26 AFI83553.1 - 4.2e-11 43.3 0.3 8.3e-11 42.4 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI83553.1 - 1.8e-08 34.3 1.0 5.6e-08 32.7 1.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AFI83553.1 - 0.0004 20.7 0.1 0.0029 18.0 0.0 2.4 2 0 0 2 2 2 1 HAMP domain PspB PF06667.12 AFI83553.1 - 0.035 14.2 0.7 0.13 12.3 0.7 2.0 1 0 0 1 1 1 0 Phage shock protein B Exonuc_VII_L PF02601.15 AFI83553.1 - 0.04 13.5 4.3 0.063 12.8 4.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMV_coat PF00721.21 AFI83553.1 - 0.046 13.6 0.2 0.086 12.7 0.2 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) DUF3972 PF13118.6 AFI83553.1 - 0.049 14.1 1.4 0.11 13.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) DUF3764 PF12594.8 AFI83553.1 - 0.13 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) Imm59 PF15597.6 AFI83553.1 - 0.16 12.5 0.4 0.16 12.5 0.4 3.0 4 0 0 4 4 4 0 Immunity protein 59 DAGK_prokar PF01219.19 AFI83554.1 - 1.1e-21 76.5 3.6 1.2e-21 76.4 3.6 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase Sulfatase PF00884.23 AFI83555.1 - 1.7e-38 132.8 0.0 2.8e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Glyco_hydro_26 PF02156.15 AFI83555.1 - 0.028 13.9 0.1 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 PSP PF04046.16 AFI83555.1 - 0.067 13.1 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 PSP BacA PF02673.18 AFI83556.1 - 1.1e-51 176.0 5.8 1.3e-51 175.8 5.8 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA TauE PF01925.19 AFI83556.1 - 3.3e-05 23.6 12.5 4.1e-05 23.3 12.5 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE SLATT_1 PF18181.1 AFI83556.1 - 6.6 6.7 6.2 4.3 7.3 3.5 2.0 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4181 PF13789.6 AFI83557.1 - 0.0087 16.3 0.3 0.01 16.1 0.2 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4181) LapA_dom PF06305.11 AFI83557.1 - 0.039 13.8 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2681 PF10883.8 AFI83557.1 - 0.068 13.6 0.1 0.085 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ParD_like PF11903.8 AFI83558.1 - 1.9e-11 43.9 0.0 2.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system HTH_Tnp_1 PF01527.20 AFI83562.1 - 1.1e-14 54.5 0.3 1.5e-14 54.1 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AFI83562.1 - 1.2e-08 35.0 0.4 2.1e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI83562.1 - 8.9e-07 28.5 0.3 1.4e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 AFI83562.1 - 5.8e-06 25.8 0.0 8.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 AFI83562.1 - 0.0031 16.9 0.2 0.0081 15.6 0.0 1.8 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 TnpB_IS66 PF05717.13 AFI83563.1 - 5.1e-43 145.1 0.1 5.7e-43 144.9 0.1 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 AFI83564.1 - 1.2e-103 346.5 1.1 1.2e-103 346.4 0.1 1.5 2 0 0 2 2 2 1 Transposase IS66 family LZ_Tnp_IS66 PF13007.7 AFI83564.1 - 3.3e-16 59.8 4.4 7.9e-16 58.6 4.4 1.7 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain zf-IS66 PF13005.7 AFI83564.1 - 5.5e-16 58.7 2.2 1.2e-15 57.6 2.2 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 DDE_Tnp_IS66_C PF13817.6 AFI83564.1 - 1e-14 54.5 0.0 2.2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 IS66 C-terminal element DZR PF12773.7 AFI83564.1 - 0.066 13.3 1.4 0.12 12.4 1.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Sgf11 PF08209.11 AFI83564.1 - 0.41 10.2 3.0 13 5.5 0.3 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) HipA_C PF07804.12 AFI83565.1 - 5.5e-48 163.5 0.0 7.2e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 AFI83565.1 - 1.7e-26 92.8 0.0 2.8e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 HipA N-terminal domain HTH_3 PF01381.22 AFI83566.1 - 6.2e-12 45.4 0.1 1.2e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AFI83566.1 - 1.6e-08 34.8 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AFI83566.1 - 3.9e-08 33.2 0.1 8.7e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AFI83566.1 - 4.8e-06 26.4 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AFI83566.1 - 0.0022 18.4 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AFI83566.1 - 0.003 17.4 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AFI83566.1 - 0.021 14.3 0.3 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 MqsA_antitoxin PF15731.5 AFI83566.1 - 0.065 13.3 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_AraC PF00165.23 AFI83567.1 - 0.033 14.3 0.1 0.24 11.6 0.0 2.5 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family RWP-RK PF02042.15 AFI83567.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain HTH_31 PF13560.6 AFI83567.1 - 0.099 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2220 PF09983.9 AFI83568.1 - 2.2e-05 23.9 0.1 0.00026 20.4 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) AAA_29 PF13555.6 AFI83569.1 - 0.0084 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AFI83569.1 - 0.011 15.7 0.3 0.1 12.7 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase TPR_8 PF13181.6 AFI83569.1 - 0.95 9.8 2.9 8.3 6.9 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-Q PF13094.6 AFI83570.1 - 3.1e-05 24.2 2.7 0.00022 21.5 2.7 2.2 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4559 PF15112.6 AFI83570.1 - 0.0042 16.8 1.7 0.0073 16.0 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) DNA_ligase_A_N PF04675.14 AFI83570.1 - 0.091 13.1 1.4 1.3 9.4 0.2 2.7 2 1 0 2 2 2 0 DNA ligase N terminus DUF489 PF04356.12 AFI83570.1 - 0.091 12.8 0.5 0.25 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF489) HATPase_c PF02518.26 AFI83572.1 - 0.0016 18.9 0.0 0.0035 17.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_24 PF13412.6 AFI83572.1 - 0.033 13.8 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TnsD PF15978.5 AFI83572.1 - 0.1 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_DeoR PF08220.12 AFI83573.1 - 0.0072 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HemN_C PF06969.16 AFI83573.1 - 0.0089 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 HemN C-terminal domain MarR_2 PF12802.7 AFI83573.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AFI83573.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AFI83573.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain EAP30 PF04157.16 AFI83573.1 - 0.16 11.2 0.0 0.45 9.8 0.0 1.7 1 1 0 1 1 1 0 EAP30/Vps36 family FaeA PF04703.12 AFI83573.1 - 0.17 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 FaeA-like protein Multi_ubiq PF14452.6 AFI83574.1 - 5.2e-08 33.0 0.0 6.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Multiubiquitin ThiF PF00899.21 AFI83575.1 - 6.2e-29 101.1 0.0 1.2e-28 100.2 0.0 1.3 1 1 0 1 1 1 1 ThiF family Prok-JAB PF14464.6 AFI83575.1 - 0.00053 19.7 0.0 0.00094 18.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RadC PF04002.15 AFI83575.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RadC-like JAB domain Phage_integrase PF00589.22 AFI83576.1 - 2.3e-14 53.5 0.7 1.5e-10 41.1 0.2 3.4 3 0 0 3 3 3 2 Phage integrase family TF_AP-2 PF03299.14 AFI83576.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor AP-2 Arm-DNA-bind_2 PF12167.8 AFI83579.1 - 7.3e-25 86.7 0.2 1.5e-24 85.7 0.2 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 AFI83579.1 - 8e-20 71.3 0.1 1.7e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 AFI83579.1 - 3.8e-05 23.9 0.9 0.00011 22.4 0.0 2.3 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Imm74 PF15603.6 AFI83579.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 74 ResIII PF04851.15 AFI83580.1 - 1.3e-35 122.9 0.1 7.2e-35 120.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EcoEI_R_C PF08463.10 AFI83580.1 - 2.1e-26 93.1 1.2 3.9e-26 92.2 1.2 1.5 1 0 0 1 1 1 1 EcoEI R protein C-terminal SWI2_SNF2 PF18766.1 AFI83580.1 - 4.1e-18 65.9 0.0 8.7e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N_2 PF13588.6 AFI83580.1 - 4.6e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DEAD PF00270.29 AFI83580.1 - 4.9e-08 33.0 0.0 3.4e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase HSDR_N PF04313.14 AFI83580.1 - 8.8e-08 32.3 0.3 6.2e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Type I restriction enzyme R protein N terminus (HSDR_N) Helicase_C PF00271.31 AFI83580.1 - 2e-06 28.1 0.5 5.7e-06 26.6 0.5 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_25 PF13481.6 AFI83580.1 - 0.032 13.8 0.0 0.19 11.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 AFI83580.1 - 0.033 13.4 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 AFI83580.1 - 0.19 11.5 0.0 5.4 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 AFI83581.1 - 4.6e-13 49.6 7.6 5.3e-12 46.2 5.5 2.9 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI83581.1 - 1.9e-09 37.3 1.1 1.4e-08 34.5 1.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AFI83581.1 - 2.3e-08 34.1 8.5 0.00075 19.3 1.8 2.4 1 1 1 2 2 2 2 AAA ATPase domain DUF2813 PF11398.8 AFI83581.1 - 2.5e-05 23.7 0.5 0.15 11.2 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2813) ABC_tran PF00005.27 AFI83581.1 - 0.0002 21.9 0.1 0.0061 17.1 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AAA_22 PF13401.6 AFI83581.1 - 0.002 18.4 0.1 0.53 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AFI83581.1 - 0.011 16.2 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 AFI83581.1 - 0.021 14.4 0.1 0.053 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 AFI83581.1 - 0.022 14.7 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 AFI83581.1 - 0.029 14.8 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AFI83581.1 - 0.067 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AFI83581.1 - 0.11 12.6 0.2 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AFI83581.1 - 0.37 11.3 7.7 11 6.5 7.7 2.9 1 1 0 1 1 1 0 AAA domain N6_Mtase PF02384.16 AFI83582.1 - 9.7e-64 215.6 0.0 1.5e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AFI83582.1 - 1.7e-11 44.9 0.0 5.4e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 HsdM N-terminal domain Eco57I PF07669.11 AFI83582.1 - 0.00039 20.9 0.4 0.0035 17.8 0.1 2.5 3 0 0 3 3 3 1 Eco57I restriction-modification methylase UPF0020 PF01170.18 AFI83582.1 - 0.002 17.9 0.0 0.0083 15.8 0.0 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 AFI83582.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methylase_S PF01420.19 AFI83583.1 - 3.8e-26 92.3 2.0 1.9e-14 54.2 0.0 2.3 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain SIR2_2 PF13289.6 AFI83584.1 - 1.7e-13 50.9 0.0 4.8e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 SIR2-like domain DUF87 PF01935.17 AFI83585.1 - 1.2e-33 117.2 0.0 1.8e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AFI83585.1 - 4.4e-07 29.2 0.0 3.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 AFI83585.1 - 5.3e-07 29.2 0.8 0.0005 19.5 0.2 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.7 AFI83585.1 - 0.0028 16.7 0.0 0.015 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain DEAD PF00270.29 AFI83585.1 - 0.0057 16.4 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ABC_tran PF00005.27 AFI83585.1 - 0.01 16.4 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF853 PF05872.12 AFI83585.1 - 0.021 13.4 0.1 0.27 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) PriA_3primeBD PF17764.1 AFI83585.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) AAA_22 PF13401.6 AFI83585.1 - 0.13 12.5 0.0 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Phosphorylase PF00343.20 AFI83586.1 - 0 1106.8 0.0 0 1106.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase MMR_HSR1 PF01926.23 AFI83587.1 - 4e-19 68.8 0.0 5.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AFI83587.1 - 5.1e-07 29.7 0.0 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 AFI83587.1 - 2.6e-05 23.8 0.0 3.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 AFI83587.1 - 0.0016 18.5 0.1 0.11 12.5 0.1 2.2 1 1 1 2 2 2 1 Dynamin family PNPase_C PF12111.8 AFI83587.1 - 0.33 10.4 2.1 0.83 9.1 0.1 2.2 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Cytochrom_C PF00034.21 AFI83588.1 - 2.8e-20 73.3 8.1 2.9e-09 37.9 1.0 3.2 2 2 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AFI83588.1 - 2.7e-17 62.9 1.6 9e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DUF1924 PF09086.11 AFI83588.1 - 0.0025 18.2 1.3 2.7 8.4 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1924) CCP_MauG PF03150.14 AFI83588.1 - 0.0036 17.9 0.1 2.4 8.8 0.0 2.4 2 1 0 2 2 2 2 Di-haem cytochrome c peroxidase Paired_CXXCH_1 PF09699.10 AFI83588.1 - 0.0038 16.9 0.3 1 9.2 0.1 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) DUF3365 PF11845.8 AFI83588.1 - 0.013 15.8 3.8 1.6 9.0 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) Cytochrom_NNT PF03264.14 AFI83588.1 - 0.046 13.4 0.0 6.3 6.5 0.0 2.2 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Cytochrome_C7 PF14522.6 AFI83588.1 - 0.048 13.7 0.3 13 5.8 0.0 2.4 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF2059 PF09832.9 AFI83588.1 - 0.12 12.5 0.4 21 5.2 0.0 2.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2059) ResB PF05140.14 AFI83589.1 - 1.1e-155 519.2 0.0 1.2e-155 519.0 0.0 1.0 1 0 0 1 1 1 1 ResB-like family Cytochrom_C_asm PF01578.20 AFI83590.1 - 9.3e-52 175.9 19.5 9.3e-52 175.9 19.5 2.4 2 1 0 2 2 2 1 Cytochrome C assembly protein Gram_pos_anchor PF00746.21 AFI83590.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.7 7 0 0 7 7 7 0 LPXTG cell wall anchor motif DSBA PF01323.20 AFI83591.1 - 3.8e-19 69.2 1.3 1.8e-16 60.5 1.3 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AFI83591.1 - 2e-12 47.6 0.0 2.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.6 AFI83591.1 - 4.2e-07 29.8 0.2 0.00059 19.6 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin PF00085.20 AFI83591.1 - 0.00088 19.2 0.1 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin ArsD PF06953.11 AFI83591.1 - 0.012 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD DUF953 PF06110.11 AFI83591.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Conotoxin PF02950.17 AFI83591.1 - 0.17 12.9 0.0 0.39 11.8 0.0 1.5 1 0 0 1 1 1 0 Conotoxin Glutaredoxin PF00462.24 AFI83591.1 - 0.38 11.0 3.5 1.5 9.1 0.0 2.8 2 1 1 3 3 3 0 Glutaredoxin SBP_bac_3 PF00497.20 AFI83592.1 - 7.6e-32 110.6 0.0 9.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SLT PF01464.20 AFI83592.1 - 1.6e-26 92.2 0.2 4.6e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Transglycosylase SLT domain Lig_chan-Glu_bd PF10613.9 AFI83592.1 - 0.015 15.5 0.0 0.094 12.9 0.0 2.1 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Lysozyme_like PF13702.6 AFI83592.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 Lysozyme-like MafB19-deam PF14437.6 AFI83593.1 - 6.7e-32 110.1 0.0 7.4e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AFI83593.1 - 2.5e-27 94.7 0.0 3.2e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 AFI83593.1 - 0.00026 21.1 0.2 0.00037 20.6 0.2 1.4 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 AFI83593.1 - 0.00027 21.0 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 AFI83593.1 - 0.00029 20.9 0.0 0.00048 20.2 0.0 1.3 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 AFI83593.1 - 0.0055 16.8 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 AFI83593.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 APOBEC_N PF08210.11 AFI83593.1 - 0.018 15.0 0.2 0.027 14.4 0.1 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 AFI83593.1 - 0.055 13.5 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Glycos_transf_N PF04413.16 AFI83594.1 - 5.5e-70 234.6 0.0 8e-70 234.1 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glycos_transf_1 PF00534.20 AFI83594.1 - 4.7e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI83594.1 - 0.0026 18.2 0.0 0.0094 16.4 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI83594.1 - 0.0079 16.6 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 AFI83594.1 - 0.068 12.0 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Lip_A_acyltrans PF03279.13 AFI83595.1 - 1e-70 238.3 0.1 1.2e-70 238.0 0.1 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase PagL PF09411.10 AFI83596.1 - 2.8e-17 63.1 0.6 6e-17 62.0 0.6 1.7 1 1 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) OMP_b-brl PF13505.6 AFI83596.1 - 0.0042 17.2 0.9 0.42 10.7 0.5 2.5 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain DUF2917 PF11142.8 AFI83596.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Ribosomal_S9 PF00380.19 AFI83597.1 - 3.3e-47 160.0 0.5 3.7e-47 159.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 AFI83598.1 - 7.6e-57 191.0 0.4 8.7e-57 190.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 BacA PF02673.18 AFI83599.1 - 1.7e-82 277.0 14.0 2e-82 276.8 14.0 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA ECF-ribofla_trS PF07155.12 AFI83599.1 - 0.016 15.2 0.7 0.016 15.2 0.7 2.6 1 1 0 2 2 2 0 ECF-type riboflavin transporter, S component DUF3683 PF12447.8 AFI83600.1 - 1.9e-29 102.1 1.6 1.9e-29 102.1 1.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3683) FAD-oxidase_C PF02913.19 AFI83600.1 - 4e-29 102.0 3.1 6.3e-20 71.9 0.5 3.1 3 0 0 3 3 3 2 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 AFI83600.1 - 2.1e-27 95.6 0.5 9.8e-27 93.4 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain DUF3400 PF11880.8 AFI83600.1 - 7.4e-23 79.8 0.3 2.2e-22 78.3 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3400) CCG PF02754.16 AFI83600.1 - 3.1e-09 36.9 7.7 1.1e-05 25.6 0.0 3.4 4 0 0 4 4 3 2 Cysteine-rich domain Fer4_8 PF13183.6 AFI83600.1 - 3.3e-07 30.6 4.0 3.3e-07 30.6 4.0 2.6 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AFI83600.1 - 1.3e-06 28.8 4.8 0.031 14.8 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI83600.1 - 0.00072 20.1 5.8 0.00072 20.1 5.8 2.6 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AFI83600.1 - 0.0013 18.8 7.4 0.009 16.1 0.4 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 AFI83600.1 - 0.011 15.9 2.9 0.2 11.8 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain DctP PF03480.13 AFI83600.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Fer4_9 PF13187.6 AFI83600.1 - 0.17 12.1 13.9 0.4 10.9 9.4 3.2 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI83600.1 - 0.36 11.0 16.8 0.25 11.5 10.5 3.4 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AFI83600.1 - 1 10.3 12.2 0.45 11.5 6.5 3.2 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AFI83600.1 - 8.4 7.3 11.6 25 5.8 0.4 4.1 4 0 0 4 4 4 0 4Fe-4S dicluster domain Fer4 PF00037.27 AFI83600.1 - 8.5 6.4 17.9 4 7.4 2.9 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain HopJ PF08888.11 AFI83601.1 - 2.6e-47 159.6 0.1 2.9e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 HopJ type III effector protein Nitroreductase PF00881.24 AFI83602.1 - 1e-34 120.0 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AFI83602.1 - 2.8e-13 50.0 0.1 0.00055 19.6 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase DUF454 PF04304.13 AFI83603.1 - 1.6e-32 111.9 8.3 1.9e-32 111.7 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) Amastin PF07344.11 AFI83603.1 - 0.071 13.0 2.8 2.1 8.2 0.2 2.2 2 0 0 2 2 2 0 Amastin surface glycoprotein SdpI PF13630.6 AFI83603.1 - 3.8 7.7 9.4 1.3 9.2 0.6 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family MMR_HSR1 PF01926.23 AFI83605.1 - 1.5e-16 60.4 0.0 3.8e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI83605.1 - 5.6e-11 42.2 0.2 2.8e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AFI83605.1 - 1.2e-06 28.5 0.9 5.6e-06 26.4 0.9 2.1 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 AFI83605.1 - 1.8e-05 24.8 0.2 0.01 15.9 0.0 3.3 3 1 1 4 4 4 1 Dynamin family Arf PF00025.21 AFI83605.1 - 0.0033 16.9 0.1 0.076 12.5 0.1 2.3 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AFI83605.1 - 0.0053 16.3 0.0 0.59 9.6 0.0 2.3 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 AFI83605.1 - 0.012 15.4 0.1 2.5 7.8 0.1 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 AFI83605.1 - 0.022 15.3 0.0 0.049 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 AFI83605.1 - 0.034 13.1 0.3 0.1 11.6 0.1 1.8 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AFI83605.1 - 0.072 13.6 0.4 0.15 12.6 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 AFI83605.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Slp PF03843.13 AFI83606.1 - 3.4e-43 146.6 0.0 4.1e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein Slp family PepSY_TM_like_2 PF16357.5 AFI83610.1 - 0.00023 21.2 0.2 0.023 14.7 0.0 2.2 2 0 0 2 2 2 2 Putative PepSY_TM-like Polbeta PF18765.1 AFI83611.1 - 1.9e-06 27.9 0.7 1.4e-05 25.1 0.2 2.2 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase MdcG PF10620.9 AFI83611.1 - 8.2e-05 22.5 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG NTP_transf_2 PF01909.23 AFI83611.1 - 0.0027 17.9 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain 6PGD PF00393.19 AFI83612.1 - 3.1e-128 427.2 0.0 3.8e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AFI83612.1 - 5.1e-51 173.0 0.0 7.5e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AFI83612.1 - 0.0011 19.1 0.4 0.0036 17.4 0.0 2.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AFI83612.1 - 0.086 12.2 0.2 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phage_portal PF04860.12 AFI83612.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein 3HCDH_N PF02737.18 AFI83612.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SdiA-regulated PF06977.11 AFI83613.1 - 3.4e-60 203.3 0.0 4.2e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 SdiA-regulated Phytase-like PF13449.6 AFI83613.1 - 2e-07 31.2 0.7 0.00065 19.7 0.1 3.8 1 1 1 2 2 2 2 Esterase-like activity of phytase SBBP PF06739.11 AFI83613.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 Beta-propeller repeat NusG_II PF07009.11 AFI83613.1 - 0.018 15.3 0.2 0.3 11.3 0.2 2.9 3 1 0 3 3 3 0 NusG domain II DUF4394 PF14339.6 AFI83613.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) DUF4221 PF13970.6 AFI83613.1 - 0.06 12.9 0.0 0.32 10.5 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) NHL PF01436.21 AFI83613.1 - 0.073 13.1 0.2 5.6 7.2 0.0 3.8 5 0 0 5 5 5 0 NHL repeat DUF3180 PF11377.8 AFI83614.1 - 0.025 14.7 2.1 0.081 13.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) WTF PF03303.13 AFI83614.1 - 0.036 13.8 2.8 0.065 13.0 2.8 1.4 1 1 0 1 1 1 0 WTF protein TetM_leader PF08076.11 AFI83614.1 - 0.13 12.0 1.5 0.25 11.1 1.5 1.5 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide DUF2070 PF09843.9 AFI83614.1 - 2.3 6.4 8.8 2.7 6.2 8.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Acylphosphatase PF00708.18 AFI83615.1 - 5.6e-17 61.9 0.0 5.9e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase FTA4 PF13093.6 AFI83616.1 - 0.038 13.9 1.8 0.065 13.1 1.8 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FlxA PF14282.6 AFI83616.1 - 0.057 13.4 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 FlxA-like protein bZIP_1 PF00170.21 AFI83616.1 - 0.13 12.4 3.0 0.42 10.8 1.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 AFI83616.1 - 0.18 12.0 1.8 0.33 11.2 0.9 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 AFI83616.1 - 0.96 9.8 3.5 0.51 10.7 1.3 1.6 2 0 0 2 2 2 0 YlqD protein HD_4 PF13328.6 AFI83617.1 - 3.4e-08 33.4 0.0 6.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.22 AFI83617.1 - 0.027 14.7 0.2 0.051 13.8 0.2 1.6 1 1 0 1 1 1 0 HD domain DUF2802 PF10975.8 AFI83617.1 - 0.1 12.7 0.0 2.4 8.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) GMP_synt_C PF00958.22 AFI83624.1 - 4.9e-43 145.1 0.0 9.8e-43 144.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 AFI83624.1 - 1.3e-37 129.5 0.0 2.1e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 AFI83624.1 - 6.3e-13 48.4 0.1 2.5e-09 36.6 0.0 2.8 3 0 0 3 3 3 2 NAD synthase Peptidase_C26 PF07722.13 AFI83624.1 - 3.9e-12 46.4 0.0 8.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AFI83624.1 - 7.3e-06 25.0 0.1 3.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 AFI83624.1 - 2.4e-05 24.2 0.0 0.00086 19.1 0.0 2.3 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 AFI83624.1 - 8.9e-05 22.1 0.0 0.11 12.0 0.0 3.0 2 1 0 3 3 3 2 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 AFI83624.1 - 0.0017 18.1 0.9 0.0052 16.5 0.0 2.1 2 1 0 2 2 2 1 PP-loop family Arginosuc_synth PF00764.19 AFI83624.1 - 0.0046 16.3 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.14 AFI83624.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) IMPDH PF00478.25 AFI83625.1 - 3.9e-163 542.4 11.0 4.4e-163 542.2 11.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AFI83625.1 - 2.4e-19 69.5 5.4 5.7e-12 45.9 1.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 AFI83625.1 - 7.2e-12 45.3 18.0 5.5e-06 26.0 0.1 2.4 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AFI83625.1 - 2.5e-06 26.7 19.8 4.3e-06 26.0 18.0 2.2 2 1 0 2 2 2 1 FMN-dependent dehydrogenase B12-binding PF02310.19 AFI83625.1 - 0.011 15.8 1.1 0.011 15.8 1.1 1.9 2 0 0 2 2 2 0 B12 binding domain QRPTase_C PF01729.19 AFI83625.1 - 0.018 14.8 0.2 0.054 13.3 0.2 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Ubie_methyltran PF01209.18 AFI83625.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family His_biosynth PF00977.21 AFI83625.1 - 0.1 12.1 11.2 1 8.8 0.5 3.4 3 1 1 4 4 4 0 Histidine biosynthesis protein TMP-TENI PF02581.17 AFI83625.1 - 0.29 10.4 12.0 1.6 8.1 3.9 2.5 1 1 1 2 2 2 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 AFI83625.1 - 0.72 8.9 14.4 0.12 11.5 9.7 1.9 1 1 1 2 2 2 0 Conserved region in glutamate synthase NAD_binding_7 PF13241.6 AFI83625.1 - 2.1 8.8 4.4 5.6 7.5 2.5 2.6 3 1 0 3 3 3 0 Putative NAD(P)-binding Exonuc_VII_L PF02601.15 AFI83626.1 - 2.8e-104 349.0 19.4 6.1e-85 285.4 1.1 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 AFI83626.1 - 6.1e-31 106.5 0.0 2.5e-30 104.5 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 AFI83626.1 - 2.8e-06 27.2 0.0 5.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Baculo_PEP_C PF04513.12 AFI83626.1 - 0.008 16.2 8.2 0.13 12.4 2.0 2.7 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus RhoGAP-FF1 PF16512.5 AFI83626.1 - 0.0097 16.6 4.6 0.012 16.2 0.5 2.6 2 0 0 2 2 2 1 p190-A and -B Rho GAPs FF domain RecJ_OB PF17768.1 AFI83626.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 RecJ OB domain Peptidase_M23 PF01551.22 AFI83627.1 - 5.4e-31 106.7 0.6 9.1e-31 105.9 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M23 Peptidase_M23_N PF18421.1 AFI83627.1 - 3.9e-21 74.7 0.8 7.2e-21 73.9 0.8 1.5 1 0 0 1 1 1 1 Peptidase family M23 N-terminal domain NMT1 PF09084.11 AFI83628.1 - 6.8e-50 170.0 0.1 1e-48 166.2 0.0 2.4 3 0 0 3 3 3 1 NMT1/THI5 like HATPase_c PF02518.26 AFI83628.1 - 4.4e-25 88.4 0.2 1.2e-24 86.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI83628.1 - 1.6e-20 72.9 4.1 2e-20 72.6 0.4 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AFI83628.1 - 1.4e-15 57.4 0.0 3.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 AFI83628.1 - 4e-15 55.9 0.0 1.4e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AFI83628.1 - 8.5e-13 48.3 0.1 1.6e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI83628.1 - 8e-09 35.7 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI83628.1 - 8.3e-06 25.7 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AFI83628.1 - 0.00039 20.6 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_10 PF13596.6 AFI83628.1 - 0.096 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 AFI83628.1 - 0.19 11.9 0.4 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 PAS fold ABC_tran PF00005.27 AFI83629.1 - 1.7e-32 112.8 0.0 2.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AFI83629.1 - 1.9e-06 27.6 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AFI83629.1 - 8e-05 22.6 0.6 0.083 12.7 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AFI83629.1 - 0.064 13.7 0.5 0.1 13.1 0.1 1.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 AFI83629.1 - 0.068 12.6 0.3 1.7 8.0 0.3 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AFI83629.1 - 0.088 13.1 0.2 1.4 9.2 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit OstA PF03968.14 AFI83630.1 - 4.9e-24 84.7 0.5 9e-24 83.9 0.5 1.4 1 0 0 1 1 1 1 OstA-like protein SH3_3 PF08239.11 AFI83630.1 - 1e-11 44.9 0.2 2.2e-11 43.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 AFI83630.1 - 0.028 14.3 0.1 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4124 PF13511.6 AFI83630.1 - 0.65 10.4 6.6 0.39 11.1 3.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4124) LptC PF06835.13 AFI83631.1 - 6.2e-36 123.6 0.1 6.9e-36 123.4 0.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related OstA PF03968.14 AFI83631.1 - 0.078 13.2 0.1 0.18 12.0 0.1 1.8 1 1 0 1 1 1 0 OstA-like protein Hydrolase_3 PF08282.12 AFI83632.1 - 1.3e-13 51.3 0.0 5.5e-10 39.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI83632.1 - 3.1e-09 37.4 0.4 5.2e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AFI83632.1 - 9.2e-08 32.4 1.7 5.3e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AFI83632.1 - 0.018 15.2 0.2 0.038 14.1 0.2 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SIS PF01380.22 AFI83633.1 - 2.5e-28 98.5 0.7 5e-28 97.6 0.1 1.8 3 0 0 3 3 3 1 SIS domain CBS PF00571.28 AFI83633.1 - 8.3e-17 61.4 0.3 6.4e-08 32.9 0.1 3.4 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 AFI83633.1 - 0.014 15.4 0.4 0.34 10.9 0.0 2.8 2 1 1 3 3 3 0 SIS domain Na_Ca_ex PF01699.24 AFI83634.1 - 3.1e-55 186.3 37.7 1.8e-29 102.6 13.4 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MlaA PF04333.13 AFI83635.1 - 3.5e-78 261.8 0.3 4.1e-78 261.6 0.3 1.0 1 0 0 1 1 1 1 MlaA lipoprotein Glyco_transf_4 PF13439.6 AFI83636.1 - 7.3e-19 68.4 0.2 5.8e-18 65.5 0.5 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 AFI83636.1 - 4.4e-18 65.4 0.0 9e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI83636.1 - 1e-17 64.8 0.0 3.2e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AFI83636.1 - 2.8e-06 27.8 0.9 6.2e-06 26.7 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AFI83636.1 - 0.00024 21.4 0.0 0.0007 19.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AFI83636.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like Metallophos_2 PF12850.7 AFI83637.1 - 3e-12 47.1 0.5 2.7e-11 43.9 0.5 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AFI83637.1 - 4.8e-12 46.8 1.5 7.2e-12 46.2 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2200 PF09966.9 AFI83637.1 - 0.029 14.5 0.0 0.094 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Peptidase_M3 PF01432.20 AFI83638.1 - 5.8e-160 533.5 0.5 5.8e-160 533.5 0.5 1.9 2 0 0 2 2 2 1 Peptidase family M3 Thr_dehydrat_C PF00585.18 AFI83638.1 - 0.063 13.0 0.1 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase DUF4375 PF14300.6 AFI83638.1 - 8.3 6.7 7.0 24 5.2 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF2277 PF10041.9 AFI83639.1 - 0.044 14.1 0.2 0.076 13.4 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) zf-dskA_traR PF01258.17 AFI83641.1 - 4.8e-12 45.6 3.7 6.4e-12 45.2 3.7 1.2 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Auto_anti-p27 PF06677.12 AFI83641.1 - 0.0065 16.6 1.0 0.0097 16.1 1.0 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 AFI83641.1 - 0.0072 16.3 0.8 0.012 15.6 0.8 1.4 1 1 0 1 1 1 1 Double zinc ribbon zf-UBR PF02207.20 AFI83641.1 - 0.034 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) C1_1 PF00130.22 AFI83641.1 - 0.066 13.1 0.7 0.16 11.8 0.7 1.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 AFI83641.1 - 0.098 12.3 3.3 0.73 9.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PSCyt3 PF07627.11 AFI83641.1 - 0.11 12.8 0.5 4 7.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) YoeB_toxin PF06769.14 AFI83642.1 - 2e-42 143.1 0.4 2.2e-42 143.0 0.4 1.0 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system ParE_toxin PF05016.15 AFI83642.1 - 0.00029 21.4 0.0 0.00037 21.0 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HigB-like_toxin PF05015.13 AFI83642.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.5 1 1 1 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB PhdYeFM_antitox PF02604.19 AFI83643.1 - 7.7e-20 70.5 0.0 1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AFI83643.1 - 0.00013 22.0 0.1 0.00014 21.9 0.1 1.1 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system UbiD PF01977.16 AFI83645.1 - 3.6e-176 586.0 0.0 4.2e-176 585.8 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase MAPEG PF01124.18 AFI83646.1 - 1.3e-18 67.1 4.7 1.5e-18 67.0 4.7 1.0 1 0 0 1 1 1 1 MAPEG family MFS_1 PF07690.16 AFI83647.1 - 3.7e-28 98.5 54.9 3.8e-14 52.4 22.7 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily HemY_N PF07219.13 AFI83647.1 - 6.6 7.0 6.8 34 4.7 0.7 3.2 3 0 0 3 3 3 0 HemY protein N-terminus FdsD PF11390.8 AFI83648.1 - 1.6e-18 66.8 0.3 1.9e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 NADH-dependant formate dehydrogenase delta subunit FdsD FATC PF02260.20 AFI83648.1 - 0.074 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 FATC domain TraY PF05509.11 AFI83648.1 - 0.077 13.0 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 TraY domain MCD_N PF17408.2 AFI83648.1 - 0.15 12.2 0.6 1.8 8.7 0.1 2.0 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain FdhD-NarQ PF02634.15 AFI83649.1 - 1.6e-72 244.0 0.7 2.1e-72 243.7 0.7 1.0 1 0 0 1 1 1 1 FdhD/NarQ family HopW1-1 PF15457.6 AFI83649.1 - 0.075 12.3 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA Molybdopterin PF00384.22 AFI83650.1 - 6.2e-75 252.8 0.0 8.2e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI83650.1 - 1.5e-25 89.4 0.0 2.7e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer2_4 PF13510.6 AFI83650.1 - 1e-21 76.8 0.8 1.4e-20 73.1 0.3 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 AFI83650.1 - 1.1e-17 63.3 0.3 1.1e-17 63.3 0.3 3.2 4 0 0 4 4 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molybdop_Fe4S4 PF04879.16 AFI83650.1 - 2.1e-14 53.2 1.8 8.1e-14 51.4 1.8 2.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4_21 PF14697.6 AFI83650.1 - 9.3e-08 32.1 6.7 9.3e-08 32.1 6.7 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI83650.1 - 9.5e-08 32.5 16.5 3.3e-06 27.6 9.9 4.3 2 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 AFI83650.1 - 7.8e-07 28.7 19.6 4.2e-05 23.2 1.6 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AFI83650.1 - 4.3e-06 26.8 9.0 4.3e-06 26.8 9.0 3.7 3 1 2 5 5 4 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI83650.1 - 6e-05 23.1 19.2 0.0025 17.9 6.2 3.6 4 0 0 4 4 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI83650.1 - 6.5e-05 22.8 10.9 0.00015 21.7 2.0 4.1 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 AFI83650.1 - 0.00012 22.5 6.9 0.00012 22.5 6.9 3.5 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI83650.1 - 0.0013 18.7 3.2 0.0013 18.7 3.2 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AFI83650.1 - 0.0055 17.6 2.2 0.0055 17.6 2.2 3.9 4 1 0 4 4 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 AFI83650.1 - 0.0069 16.6 13.2 0.089 13.0 1.6 3.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AFI83650.1 - 0.021 15.6 9.9 0.15 12.8 0.7 3.1 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 AFI83650.1 - 0.037 14.6 10.1 0.35 11.5 2.3 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I pPIWI_RE_Z PF18155.1 AFI83650.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z Fer4_17 PF13534.6 AFI83650.1 - 1.1 9.8 21.7 0.17 12.5 0.8 4.1 5 0 0 5 5 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AFI83650.1 - 5.7 7.9 17.5 4.9 8.1 3.1 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI83650.1 - 6 7.6 24.1 0.095 13.3 2.7 4.2 4 0 0 4 4 3 0 4Fe-4S binding domain Complex1_51K PF01512.17 AFI83651.1 - 8.2e-44 149.1 0.0 1.2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AFI83651.1 - 5.7e-30 103.2 0.6 9.4e-30 102.5 0.6 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AFI83651.1 - 0.00065 19.5 0.4 0.0016 18.2 0.4 1.7 1 0 0 1 1 1 1 SLBB domain 2Fe-2S_thioredx PF01257.19 AFI83652.1 - 2.7e-42 144.1 0.1 3.1e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1450 PF07293.11 AFI83652.1 - 1.2 9.0 5.9 14 5.6 4.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1450) PBP_like PF12727.7 AFI83653.1 - 3e-53 179.8 0.0 4e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain HTH_1 PF00126.27 AFI83653.1 - 3.8e-09 36.4 0.8 1.8e-08 34.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Phosphonate-bd PF12974.7 AFI83653.1 - 2.4e-05 24.0 0.0 0.00029 20.5 0.0 2.1 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 AFI83653.1 - 0.00063 19.2 0.1 0.0031 16.9 0.1 2.1 1 1 0 1 1 1 1 LysR substrate binding domain T7SS_ESX_EspC PF10824.8 AFI83653.1 - 0.033 14.6 0.7 0.082 13.4 0.7 1.7 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Baculo_PEP_C PF04513.12 AFI83653.1 - 0.08 13.0 0.6 0.17 11.9 0.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PdxJ PF03740.13 AFI83653.1 - 0.14 11.3 1.2 1.7 7.7 0.4 2.1 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ MoaE PF02391.17 AFI83654.1 - 7.3e-30 103.6 0.0 8.6e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 AFI83655.1 - 9e-16 58.3 0.0 1e-15 58.1 0.0 1.0 1 0 0 1 1 1 1 ThiS family Ub-Mut7C PF14451.6 AFI83655.1 - 0.021 14.7 0.1 0.085 12.7 0.1 1.8 1 1 0 1 1 1 0 Mut7-C ubiquitin DUF3465 PF11948.8 AFI83655.1 - 0.048 13.5 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3465) COX6A PF02046.15 AFI83655.1 - 0.049 14.1 0.0 0.054 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa MoaC PF01967.21 AFI83656.1 - 6.8e-58 194.6 3.1 7.8e-58 194.4 3.1 1.0 1 0 0 1 1 1 1 MoaC family Porin_O_P PF07396.11 AFI83657.1 - 7.2e-52 176.8 0.7 8.6e-52 176.5 0.7 1.1 1 0 0 1 1 1 1 Phosphate-selective porin O and P PaRep2b PF07775.11 AFI83657.1 - 0.08 11.4 0.1 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 PaRep2b protein Porin_O_P PF07396.11 AFI83658.1 - 2.6e-68 230.8 3.2 3.1e-68 230.6 3.2 1.1 1 0 0 1 1 1 1 Phosphate-selective porin O and P PBP_like_2 PF12849.7 AFI83659.1 - 4.6e-29 102.0 0.5 5.5e-29 101.7 0.5 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AFI83659.1 - 1.9e-07 30.4 0.0 2.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AFI83659.1 - 7.9e-06 25.8 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AFI83659.1 - 9.5e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain DUF2333 PF10095.9 AFI83660.1 - 5e-160 531.9 0.2 5.9e-160 531.7 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) 7TM_GPCR_Srd PF10317.9 AFI83660.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd ABC_tran PF00005.27 AFI83661.1 - 1.1e-26 94.0 0.0 3.7e-26 92.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AFI83661.1 - 9.5e-10 38.8 0.1 7.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AFI83661.1 - 0.00013 21.8 0.1 0.56 9.9 0.0 2.1 1 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AFI83661.1 - 0.00069 19.1 0.1 0.26 10.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AFI83661.1 - 0.0024 18.4 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI83661.1 - 0.0072 16.0 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AFI83661.1 - 0.047 13.4 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AFI83661.1 - 0.071 13.4 0.1 0.26 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AFI83661.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 AFI83662.1 - 1.1e-08 34.7 12.0 1.1e-08 34.7 12.0 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein CcmB PF03379.13 AFI83662.1 - 1.2e-07 31.5 1.7 1.2e-07 31.5 1.7 1.8 3 1 0 3 3 3 1 CcmB protein ABC2_membrane_4 PF12730.7 AFI83662.1 - 1.1e-05 25.5 10.0 1.1e-05 25.5 10.0 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AFI83662.1 - 6.1e-05 22.3 36.6 0.001 18.2 36.0 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AFI83662.1 - 0.0058 16.2 20.4 0.024 14.2 19.6 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF2798 PF11391.8 AFI83662.1 - 0.0074 16.3 0.9 0.0074 16.3 0.9 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF2798) ABC_transp_aux PF09822.9 AFI83663.1 - 4e-68 229.8 0.1 1.9e-67 227.5 0.0 1.9 2 0 0 2 2 2 1 ABC-type uncharacterized transport system ATP1G1_PLM_MAT8 PF02038.16 AFI83663.1 - 0.11 11.9 0.5 0.28 10.6 0.5 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4340 PF14238.6 AFI83664.1 - 1.1e-11 45.1 0.0 2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4340) CheW PF01584.19 AFI83665.1 - 5.5e-33 113.5 0.1 8.6e-33 112.9 0.1 1.3 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AFI83665.1 - 2.6e-16 59.8 0.7 5.1e-16 58.8 0.7 1.5 1 0 0 1 1 1 1 Response regulator receiver domain ChapFlgA PF13144.6 AFI83666.1 - 7.1e-34 116.5 4.6 1.1e-33 115.9 4.6 1.3 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation ChapFlgA_N PF17656.1 AFI83666.1 - 7.2e-11 42.1 0.1 1.7e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 FlgA N-terminal domain SAF PF08666.12 AFI83666.1 - 3.9e-06 27.4 0.2 1.3e-05 25.7 0.1 1.9 2 0 0 2 2 2 1 SAF domain FlgM PF04316.13 AFI83667.1 - 5.3e-18 65.1 2.3 5.3e-18 65.1 2.3 1.5 2 0 0 2 2 2 1 Anti-sigma-28 factor, FlgM DUF2460 PF09343.10 AFI83667.1 - 0.0062 16.1 0.1 0.0068 15.9 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) IL33 PF15095.6 AFI83667.1 - 0.0065 16.0 0.2 0.0074 15.8 0.2 1.0 1 0 0 1 1 1 1 Interleukin 33 CCB1 PF12046.8 AFI83667.1 - 0.014 14.7 0.8 1.6 8.1 0.3 2.0 1 1 1 2 2 2 0 Cofactor assembly of complex C subunit B Spc7 PF08317.11 AFI83667.1 - 0.03 13.2 1.2 0.036 12.9 1.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4404 PF14357.6 AFI83667.1 - 0.048 14.3 2.2 0.1 13.3 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ABC_tran_CTD PF16326.5 AFI83667.1 - 0.17 12.2 1.7 0.87 9.9 1.1 2.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 AFI83667.1 - 0.29 11.2 3.1 9.1 6.4 1.6 2.3 2 1 0 2 2 2 0 TolA binding protein trimerisation FlgN PF05130.12 AFI83668.1 - 5.9e-27 95.0 0.8 6.5e-27 94.8 0.8 1.0 1 0 0 1 1 1 1 FlgN protein Ferrochelatase PF00762.19 AFI83669.1 - 1.4e-92 310.2 0.0 1.8e-92 309.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Epimerase PF01370.21 AFI83670.1 - 7e-22 78.1 0.0 9.4e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 AFI83670.1 - 2.8e-19 68.7 0.0 6.4e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) GDP_Man_Dehyd PF16363.5 AFI83670.1 - 9.9e-09 35.0 0.0 3.3e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AFI83670.1 - 2.7e-07 30.0 0.0 8.9e-07 28.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AFI83670.1 - 5.4e-05 22.7 0.3 0.00024 20.6 0.1 2.0 2 1 1 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AFI83670.1 - 9.2e-05 21.7 0.2 0.0064 15.7 0.1 2.9 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 AFI83670.1 - 0.00025 21.0 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AFI83670.1 - 0.00087 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 AFI83670.1 - 0.0016 18.4 0.1 0.0085 16.0 0.1 2.0 1 1 1 2 2 2 1 KR domain NAD_binding_2 PF03446.15 AFI83670.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AFI83670.1 - 0.0049 17.4 0.0 0.014 16.0 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 AFI83670.1 - 0.0071 15.5 0.0 0.043 12.9 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AFI83670.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1722 PF08349.11 AFI83671.1 - 2.9e-44 150.1 3.1 4.1e-44 149.6 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF523 PF04463.12 AFI83671.1 - 1.1e-32 112.9 0.0 2.3e-32 111.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF523) Hist_deacetyl PF00850.19 AFI83672.1 - 5.6e-81 272.4 3.6 3.3e-77 260.0 0.5 2.0 1 1 1 2 2 2 2 Histone deacetylase domain ECH_1 PF00378.20 AFI83673.1 - 2.8e-21 76.0 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 AFI83673.1 - 4.5e-09 36.3 0.1 6e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HATPase_c PF02518.26 AFI83674.1 - 1.9e-27 96.0 1.0 2.8e-27 95.4 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AFI83674.1 - 1.4e-25 89.7 1.0 3.6e-24 85.1 0.4 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AFI83674.1 - 2.3e-18 66.0 3.8 4.8e-18 65.0 0.2 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AFI83674.1 - 1.9e-05 24.8 0.8 6.5e-05 23.1 0.5 2.1 2 0 0 2 2 2 1 Hpt domain FliG_C PF01706.16 AFI83674.1 - 0.037 14.2 0.2 0.13 12.5 0.2 1.9 1 0 0 1 1 1 0 FliG C-terminal domain HATPase_c_3 PF13589.6 AFI83674.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 AFI83674.1 - 0.1 13.0 0.6 1.4 9.3 0.1 3.0 2 1 1 3 3 3 0 Flagellar regulatory protein FleQ Wzy_C PF04932.15 AFI83674.1 - 1.4 8.6 7.5 0.14 11.8 0.9 2.2 2 0 0 2 2 2 0 O-Antigen ligase Response_reg PF00072.24 AFI83675.1 - 2.7e-24 85.5 0.2 4.8e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AFI83675.1 - 1.4e-19 70.5 0.8 2.9e-19 69.5 0.3 1.8 2 0 0 2 2 2 1 HD domain HD_5 PF13487.6 AFI83675.1 - 3.6e-15 56.0 0.2 8e-15 54.9 0.2 1.6 1 0 0 1 1 1 1 HD domain FleQ PF06490.11 AFI83675.1 - 0.013 15.8 0.1 0.027 14.8 0.1 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ BRCT_3 PF18428.1 AFI83675.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CbiX PF01903.17 AFI83676.1 - 1.8e-25 89.3 0.1 2.1e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 AFI83676.1 - 0.0013 18.1 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) ILVD_EDD PF00920.21 AFI83679.1 - 5.5e-214 711.6 4.4 6.3e-214 711.4 4.4 1.0 1 0 0 1 1 1 1 Dehydratase family FA_desaturase PF00487.24 AFI83680.1 - 2.5e-34 119.3 26.7 2.5e-34 119.3 26.7 1.9 1 1 1 2 2 2 2 Fatty acid desaturase DUF4191 PF13829.6 AFI83680.1 - 5.2 6.4 7.1 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TFIIE_alpha PF02002.17 AFI83681.1 - 0.00013 21.8 0.3 0.2 11.5 0.1 2.9 1 1 2 3 3 3 2 TFIIE alpha subunit HTH_27 PF13463.6 AFI83681.1 - 0.00048 20.6 0.0 0.00088 19.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AFI83681.1 - 0.00096 19.0 0.0 0.0035 17.2 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 AFI83681.1 - 0.0016 19.1 0.0 0.0034 18.0 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal DUF2250 PF10007.9 AFI83681.1 - 0.0017 18.4 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) MarR PF01047.22 AFI83681.1 - 0.0082 16.0 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_45 PF14947.6 AFI83681.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix MarR_2 PF12802.7 AFI83681.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family HemN_C PF06969.16 AFI83681.1 - 0.03 14.4 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 HemN C-terminal domain Pkinase PF00069.25 AFI83682.1 - 1.2e-32 113.3 0.0 1.7e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AFI83682.1 - 1.3e-24 86.9 0.0 1.8e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AFI83682.1 - 0.001 19.0 0.0 0.02 14.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AFI83682.1 - 0.006 15.4 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 AFI83682.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_RNA_pol PF03293.14 AFI83682.1 - 0.078 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit DUF2299 PF10061.9 AFI83682.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) ELF PF03317.13 AFI83683.1 - 0.074 13.0 0.1 0.27 11.3 0.1 1.9 1 0 0 1 1 1 0 ELF protein PP2C_2 PF13672.6 AFI83684.1 - 2.5e-07 30.5 0.0 1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 AFI83684.1 - 5.4e-06 26.5 0.1 2.1e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 AFI83684.1 - 5.1e-05 23.0 0.1 0.099 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Cullin_Nedd8 PF10557.9 AFI83684.1 - 0.067 13.2 1.2 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Cullin protein neddylation domain Pep_deformylase PF01327.21 AFI83685.1 - 0.068 12.8 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 Polypeptide deformylase GutM PF06923.11 AFI83685.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) IstB_IS21 PF01695.17 AFI83686.1 - 2.6e-54 183.6 0.2 3.5e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein IstB_IS21_ATP PF08483.11 AFI83686.1 - 9e-12 44.7 0.1 2.2e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding N-terminal PhoH PF02562.16 AFI83686.1 - 0.00022 20.7 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 AFI83686.1 - 0.00039 20.4 1.1 0.0022 17.9 0.1 2.4 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 AFI83686.1 - 0.0006 20.2 0.1 0.0012 19.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AFI83686.1 - 0.00073 19.8 3.1 0.0014 18.9 0.9 2.5 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 AFI83686.1 - 0.00075 19.5 0.2 0.0015 18.5 0.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 AFI83686.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 AFI83686.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AFI83686.1 - 0.0035 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 AFI83686.1 - 0.0039 17.6 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 AFI83686.1 - 0.0043 17.1 0.0 0.013 15.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 AFI83686.1 - 0.0047 17.4 0.0 0.0068 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AFI83686.1 - 0.0048 17.5 0.0 0.0096 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AFI83686.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 AFI83686.1 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Sigma54_activat PF00158.26 AFI83686.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ArsA_ATPase PF02374.15 AFI83686.1 - 0.015 14.5 0.1 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase Microtub_bd PF16796.5 AFI83686.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding Sigma54_activ_2 PF14532.6 AFI83686.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 AFI83686.1 - 0.022 15.3 0.1 0.065 13.7 0.1 1.9 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta2 PF13177.6 AFI83686.1 - 0.028 14.2 0.3 1.7 8.4 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 AFI83686.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 AFI83686.1 - 0.05 13.4 0.2 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase PduV-EutP PF10662.9 AFI83686.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 AFI83686.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 AFI83686.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 AFI83686.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AFI83686.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC rve PF00665.26 AFI83687.1 - 4.6e-18 65.5 0.0 1.9e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 AFI83687.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AFI83687.1 - 0.019 14.4 0.0 0.095 12.2 0.0 2.2 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.7 AFI83687.1 - 0.047 13.6 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 MarR family LuxQ-periplasm PF09308.10 AFI83687.1 - 0.078 12.5 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 LuxQ, periplasmic DUF4167 PF13763.6 AFI83687.1 - 0.093 12.9 0.1 3.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) CoiA PF06054.11 AFI83688.1 - 1.7e-06 27.5 0.7 4.2e-06 26.2 0.7 1.6 1 0 0 1 1 1 1 Competence protein CoiA-like family DNA_ligase_ZBD PF03119.16 AFI83688.1 - 0.0035 17.3 0.1 0.0065 16.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_11 PF11682.8 AFI83688.1 - 0.042 13.9 0.2 0.083 12.9 0.2 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon Acetyltransf_10 PF13673.7 AFI83689.1 - 3.1e-07 30.4 0.0 1.5e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AFI83689.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AFI83689.1 - 2.2e-05 24.7 0.0 2.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family VEK-30 PF12107.8 AFI83689.1 - 0.09 12.7 0.2 0.28 11.1 0.2 1.9 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF1731 PF08338.11 AFI83689.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) DUF1778 PF08681.11 AFI83690.1 - 5.1e-06 26.3 0.3 5.4e-06 26.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) DUF2149 PF09919.9 AFI83692.1 - 2.3e-27 95.0 0.1 2.6e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) Synaptobrevin PF00957.21 AFI83692.1 - 0.53 10.1 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Synaptobrevin MotA_ExbB PF01618.16 AFI83693.1 - 7.5e-06 25.7 0.7 1e-05 25.3 0.7 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family CobN-Mg_chel PF02514.16 AFI83694.1 - 1.9e-289 963.1 0.9 2.2e-289 962.8 0.9 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase DUF2451 PF10474.9 AFI83694.1 - 0.017 14.9 0.7 0.082 12.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) SF3A3 PF16837.5 AFI83694.1 - 0.07 13.6 0.1 0.85 10.2 0.0 2.9 4 0 0 4 4 4 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TonB_dep_Rec PF00593.24 AFI83695.1 - 4.4e-53 181.8 12.0 4.4e-53 181.8 12.0 1.6 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83695.1 - 4.8e-25 88.2 0.1 1.5e-24 86.7 0.1 1.9 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI83695.1 - 1.6e-10 40.6 0.6 7.5e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family Porin_4 PF13609.6 AFI83695.1 - 9.8e-08 32.1 2.6 2.5e-07 30.8 2.6 1.7 1 1 0 1 1 1 1 Gram-negative porin DUF502 PF04367.13 AFI83696.1 - 1.7e-23 82.5 0.0 2.5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF502) DrsE_2 PF13686.6 AFI83697.1 - 2.3e-50 170.4 0.1 2.6e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 DsrE/DsrF/DrsH-like family DrsE PF02635.15 AFI83697.1 - 9e-09 35.7 0.0 2e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 DsrE/DsrF-like family TusA PF01206.17 AFI83698.1 - 1.9e-21 75.6 0.0 2.1e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA Peptidase_M48 PF01435.18 AFI83699.1 - 1.7e-31 109.6 0.0 2.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 TPR_19 PF14559.6 AFI83699.1 - 8.4e-11 42.2 12.8 0.00018 21.9 0.6 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI83699.1 - 2.7e-08 33.9 7.0 5.7e-06 26.5 1.2 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AFI83699.1 - 6.7e-08 32.7 12.5 0.0068 17.1 0.5 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AFI83699.1 - 5.6e-07 30.1 12.2 7.7e-06 26.5 0.4 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 AFI83699.1 - 0.0065 16.6 3.4 0.3 11.4 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AFI83699.1 - 0.0083 16.2 7.1 1.4 9.2 0.2 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AFI83699.1 - 0.019 15.6 9.4 0.075 13.7 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 AFI83699.1 - 0.02 15.3 3.6 9.8 6.6 0.0 3.2 1 1 2 3 3 3 0 Bacterial transcriptional activator domain SprT-like PF10263.9 AFI83699.1 - 0.041 13.7 0.1 0.087 12.7 0.1 1.5 1 0 0 1 1 1 0 SprT-like family HPP PF04982.13 AFI83699.1 - 0.041 14.1 0.5 0.073 13.3 0.5 1.3 1 0 0 1 1 1 0 HPP family HTH_20 PF12840.7 AFI83699.1 - 0.042 13.9 0.9 5.9 7.0 0.2 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4157 PF13699.6 AFI83699.1 - 0.076 13.3 0.3 0.21 11.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Fis1_TPR_C PF14853.6 AFI83699.1 - 0.083 13.0 0.2 0.34 11.0 0.2 2.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 AFI83699.1 - 0.16 12.3 15.0 0.81 10.0 3.4 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AFI83699.1 - 0.21 12.3 0.3 0.21 12.3 0.3 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 AFI83699.1 - 1.4 9.5 8.9 33 5.2 0.4 4.5 4 1 0 4 4 3 0 Tetratricopeptide repeat SoxY PF13501.6 AFI83700.1 - 3e-25 88.6 0.0 3.9e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Sulfur oxidation protein SoxY SoxZ PF08770.11 AFI83701.1 - 1.3e-27 95.4 0.0 1.5e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ HisKA_3 PF07730.13 AFI83702.1 - 3.2e-13 50.0 0.6 3.2e-13 50.0 0.6 3.4 4 0 0 4 4 3 1 Histidine kinase PAS PF00989.25 AFI83702.1 - 3.7e-11 43.0 0.0 1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AFI83702.1 - 5.4e-10 39.5 0.0 1.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AFI83702.1 - 6.7e-10 39.2 0.0 2e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AFI83702.1 - 3.6e-08 33.9 0.3 1.1e-07 32.4 0.3 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AFI83702.1 - 1e-05 25.8 0.6 6.1e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 AFI83702.1 - 0.0001 22.2 0.2 0.00023 21.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AFI83702.1 - 0.0009 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AFI83702.1 - 0.0029 17.6 0.0 0.0077 16.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain LapD_MoxY_N PF16448.5 AFI83702.1 - 0.0048 16.8 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 LapD/MoxY periplasmic domain PAS_10 PF13596.6 AFI83702.1 - 0.0084 16.7 0.0 0.034 14.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain Saf_2TM PF18303.1 AFI83702.1 - 0.059 13.0 0.6 1.7 8.2 0.3 2.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PAS_7 PF12860.7 AFI83702.1 - 0.078 13.1 0.0 2.2 8.5 0.0 3.2 2 1 0 2 2 2 0 PAS fold Response_reg PF00072.24 AFI83703.1 - 1.5e-29 102.4 0.0 2.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AFI83703.1 - 5e-22 77.2 0.5 8.2e-22 76.5 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI83703.1 - 1.1e-06 28.2 0.0 3.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_7 PF02796.15 AFI83703.1 - 4.2e-05 23.5 0.0 0.0002 21.4 0.0 2.1 3 0 0 3 3 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 AFI83703.1 - 0.00012 21.7 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 AFI83703.1 - 0.00013 21.6 0.0 0.00048 19.8 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AFI83703.1 - 0.0002 20.8 0.0 0.0005 19.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AFI83703.1 - 0.00046 20.6 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AFI83703.1 - 0.0013 18.1 0.0 0.0072 15.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 AFI83703.1 - 0.0026 17.8 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AFI83703.1 - 0.0044 17.0 0.0 0.019 15.0 0.0 2.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_5 PF01022.20 AFI83703.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AFI83703.1 - 0.0098 15.9 0.1 0.091 12.8 0.0 2.4 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 AFI83703.1 - 0.043 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AFI83703.1 - 0.047 13.6 0.1 2.7 8.0 0.0 3.0 4 0 0 4 4 4 0 HTH domain Hjc PF01870.18 AFI83703.1 - 0.078 13.0 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) HisKA_3 PF07730.13 AFI83704.1 - 1.2e-09 38.5 1.0 2.6e-09 37.5 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AFI83704.1 - 3.5e-05 24.3 0.3 0.0014 19.1 0.3 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2062 PF09835.9 AFI83704.1 - 0.0027 17.6 0.2 0.005 16.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) HATPase_c_2 PF13581.6 AFI83704.1 - 0.021 14.8 0.0 0.061 13.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain LRR_6 PF13516.6 AFI83704.1 - 0.06 13.4 0.9 0.38 10.9 0.6 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Response_reg PF00072.24 AFI83705.1 - 4.2e-29 101.0 0.2 6.6e-29 100.3 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AFI83705.1 - 5.8e-14 51.4 0.0 9.8e-14 50.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF5338 PF17273.2 AFI83705.1 - 0.042 13.9 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5338) HTH_40 PF14493.6 AFI83705.1 - 0.061 13.8 0.0 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 AFI83705.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase PQQ PF01011.21 AFI83706.1 - 9.3e-27 91.7 15.8 5.3e-07 29.3 0.0 7.6 7 0 0 7 7 7 6 PQQ enzyme repeat PQQ_2 PF13360.6 AFI83706.1 - 5.5e-17 62.1 0.2 2.4e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 AFI83706.1 - 3.9e-11 43.1 8.1 0.0046 17.4 0.3 5.9 5 0 0 5 5 5 4 PQQ-like domain Lactamase_B_2 PF12706.7 AFI83707.1 - 1.2e-47 162.0 0.2 1.5e-47 161.8 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TENA_THI-4 PF03070.16 AFI83708.1 - 8.1e-63 212.0 0.3 9.2e-63 211.8 0.3 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Glutaredoxin2_C PF04399.13 AFI83708.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Ecotin PF03974.13 AFI83708.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Ecotin PqqD PF05402.12 AFI83709.1 - 8.4e-11 42.0 0.2 9.9e-11 41.8 0.2 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) MPTase-PolyVal PF18818.1 AFI83709.1 - 0.009 16.1 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase superfamily domain HTH_5 PF01022.20 AFI83709.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Radical_SAM PF04055.21 AFI83710.1 - 2.9e-25 89.6 0.0 6.6e-25 88.4 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 AFI83710.1 - 1.9e-10 41.1 0.3 4.3e-10 40.0 0.3 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AFI83710.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AFI83710.1 - 2e-06 27.9 0.0 4.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain HMGL-like PF00682.19 AFI83710.1 - 0.012 15.2 0.0 0.039 13.5 0.0 1.7 1 1 0 1 1 1 0 HMGL-like Peripla_BP_6 PF13458.6 AFI83710.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein ABC_tran PF00005.27 AFI83711.1 - 8.7e-30 104.0 0.0 1.2e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI83711.1 - 8.5e-10 38.9 1.3 1.2e-06 28.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI83711.1 - 0.0073 15.8 0.0 0.03 13.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 AFI83711.1 - 0.017 15.8 0.0 0.038 14.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_29 PF13555.6 AFI83711.1 - 0.019 14.7 0.1 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 AFI83711.1 - 0.029 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 AFI83711.1 - 0.035 13.8 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AFI83711.1 - 0.046 14.2 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 AFI83712.1 - 2.2e-32 112.2 21.4 2.2e-32 112.2 21.4 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AFI83712.1 - 2.3e-17 63.1 30.8 2.8e-17 62.8 30.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AFI83712.1 - 8.5e-10 38.4 22.3 1.1e-09 38.0 22.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein CcmB PF03379.13 AFI83712.1 - 0.00029 20.4 20.1 0.00029 20.4 20.1 2.0 1 1 0 2 2 2 1 CcmB protein ABC2_membrane_4 PF12730.7 AFI83712.1 - 0.0005 20.1 19.5 0.00094 19.2 16.5 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AFI83712.1 - 1.1 8.8 26.2 2.7 7.5 26.2 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein PCMT PF01135.19 AFI83713.1 - 1.5e-39 135.9 0.0 1.8e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AFI83713.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83713.1 - 2e-06 28.4 0.1 7.6e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI83713.1 - 4.1e-06 27.4 0.1 1.1e-05 26.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 AFI83713.1 - 4.9e-06 25.8 0.0 7.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 AFI83713.1 - 6.1e-06 26.2 0.0 3.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 AFI83713.1 - 0.00015 21.3 0.1 0.00066 19.2 0.0 2.0 1 1 1 2 2 2 1 Putative methyltransferase CMAS PF02353.20 AFI83713.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 AFI83713.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 AFI83713.1 - 0.089 12.3 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 AFI83713.1 - 0.16 12.7 0.0 0.34 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.20 AFI83714.1 - 1.3e-14 54.6 0.0 1.5e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Vert_IL3-reg_TF PF06529.11 AFI83714.1 - 0.076 12.1 0.0 0.085 12.0 0.0 1.0 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor FleQ PF06490.11 AFI83714.1 - 0.08 13.3 0.2 0.12 12.8 0.2 1.4 1 1 0 1 1 1 0 Flagellar regulatory protein FleQ RuBisCO_large PF00016.20 AFI83714.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Acetyltransf_18 PF18014.1 AFI83714.1 - 0.14 12.0 0.2 1.5 8.6 0.2 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain OEP PF02321.18 AFI83715.1 - 4.4e-50 170.1 28.2 8.6e-27 94.2 6.2 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein SPATA24 PF15175.6 AFI83715.1 - 0.015 15.2 0.1 0.046 13.6 0.1 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 CbiX PF01903.17 AFI83715.1 - 0.026 14.9 0.0 0.088 13.1 0.0 1.9 1 0 0 1 1 1 0 CbiX YjbR PF04237.13 AFI83715.1 - 0.1 13.2 0.0 0.36 11.4 0.0 2.0 1 0 0 1 1 1 0 YjbR Isochorismatase PF00857.20 AFI83716.1 - 7e-34 117.5 0.3 8e-34 117.3 0.3 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1289 PF06945.13 AFI83717.1 - 5.3e-18 64.6 5.1 6.8e-18 64.2 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Radical_SAM PF04055.21 AFI83718.1 - 1.8e-15 57.7 0.0 8.3e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AFI83718.1 - 2.6e-15 56.5 0.0 4.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain DUF4080 PF13311.6 AFI83718.1 - 2.7e-09 37.5 0.0 1.1e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4080) Exonuc_X-T_C PF08411.10 AFI83719.1 - 1.1e-95 319.8 0.3 1.4e-95 319.5 0.3 1.1 1 0 0 1 1 1 1 Exonuclease C-terminal RNase_T PF00929.24 AFI83719.1 - 7.8e-26 91.6 0.0 1.4e-25 90.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Aminotran_3 PF00202.21 AFI83720.1 - 1.9e-76 257.3 0.1 2.6e-76 256.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AFI83720.1 - 0.002 17.4 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF167 PF02594.16 AFI83720.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 LapD_MoxY_N PF16448.5 AFI83721.1 - 3e-20 72.4 0.0 5.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 LapD/MoxY periplasmic domain HisKA_3 PF07730.13 AFI83721.1 - 5.4e-10 39.6 2.6 7.3e-10 39.2 0.6 2.4 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AFI83721.1 - 1.2e-09 38.6 0.2 7.7e-09 36.0 0.2 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AFI83721.1 - 5.4e-08 33.1 0.2 5.8e-07 29.8 0.1 2.7 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 AFI83721.1 - 2.2e-05 24.4 0.0 5.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AFI83721.1 - 0.00069 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GST_C PF00043.25 AFI83721.1 - 0.021 15.0 0.0 20 5.5 0.0 3.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain TilS PF09179.11 AFI83721.1 - 0.022 15.3 0.9 0.12 12.9 0.1 2.6 3 0 0 3 3 3 0 TilS substrate binding domain Response_reg PF00072.24 AFI83722.1 - 6.1e-29 100.4 0.0 9.7e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AFI83722.1 - 5.9e-16 57.8 0.2 1e-15 57.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI83722.1 - 4.5e-06 26.3 0.1 8.9e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AFI83722.1 - 7.1e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF2089 PF09862.9 AFI83722.1 - 0.00029 20.9 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) Sigma70_r4 PF04545.16 AFI83722.1 - 0.00084 18.8 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI83722.1 - 0.0014 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 ECF sigma factor HTH_10 PF04967.12 AFI83722.1 - 0.0019 17.9 0.1 0.4 10.5 0.0 2.7 2 0 0 2 2 2 1 HTH DNA binding domain HTH_38 PF13936.6 AFI83722.1 - 0.002 17.9 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 AFI83722.1 - 0.0026 17.8 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AFI83722.1 - 0.0044 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 AFI83722.1 - 0.012 15.0 0.0 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 AFI83722.1 - 0.019 14.9 0.8 0.052 13.5 0.3 1.9 2 0 0 2 2 2 0 HTH domain HTH_40 PF14493.6 AFI83722.1 - 0.02 15.3 0.1 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 AFI83722.1 - 0.026 14.1 0.1 0.059 12.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 AFI83722.1 - 0.055 13.5 0.0 2.7 8.1 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix AbrB_C PF18277.1 AFI83722.1 - 0.13 11.9 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 AbrB C-terminal domain HTH_28 PF13518.6 AFI83722.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3450 PF11932.8 AFI83723.1 - 1.3e-91 306.2 11.1 1.5e-91 306.0 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMPIT PF07851.13 AFI83723.1 - 0.048 12.9 1.8 0.065 12.5 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein KLRAQ PF10205.9 AFI83723.1 - 0.049 13.9 3.2 0.12 12.6 3.2 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein MukB PF04310.12 AFI83723.1 - 0.11 12.3 0.3 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 MukB N-terminal DUF948 PF06103.11 AFI83723.1 - 0.64 10.3 3.5 10 6.5 3.4 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 AFI83723.1 - 2.2 7.3 7.1 0.88 8.6 4.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 AFI83723.1 - 3.5 8.3 5.9 22 5.7 5.9 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Arg_decarbox_C PF17944.1 AFI83723.1 - 7.4 7.2 8.4 10 6.7 0.2 3.7 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension MotA_ExbB PF01618.16 AFI83724.1 - 2.4e-29 101.7 1.4 2.4e-29 101.7 1.4 2.6 2 2 0 3 3 3 1 MotA/TolQ/ExbB proton channel family Bac_transf PF02397.16 AFI83724.1 - 0.051 13.2 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial sugar transferase Phage_holin_5_2 PF16079.5 AFI83724.1 - 0.056 13.8 1.5 0.68 10.3 0.1 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DUF2370 PF10176.9 AFI83724.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TPR_20 PF14561.6 AFI83724.1 - 0.19 12.1 6.0 1.1 9.7 3.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4342 PF14242.6 AFI83724.1 - 0.31 11.1 3.4 3.6 7.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) SieB PF14163.6 AFI83724.1 - 0.32 10.5 1.6 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B MotA_ExbB PF01618.16 AFI83725.1 - 4.2e-21 75.0 0.7 5.2e-21 74.7 0.7 1.1 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AFI83726.1 - 4e-32 111.1 0.2 4.4e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR SDH_sah PF01972.16 AFI83726.1 - 0.046 12.7 0.1 0.096 11.7 0.1 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase TonB_C PF03544.14 AFI83727.1 - 4.4e-24 84.7 0.2 8.3e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AFI83727.1 - 0.002 18.3 0.1 0.002 18.3 0.1 1.7 2 0 0 2 2 2 1 TonB C terminal TPR_16 PF13432.6 AFI83728.1 - 3.9e-18 65.8 16.0 0.00012 22.7 0.0 5.4 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 AFI83728.1 - 5.8e-14 51.6 22.0 0.11 13.4 0.1 8.3 3 2 6 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 AFI83728.1 - 3.1e-12 45.7 15.4 0.004 17.3 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 AFI83728.1 - 5.6e-12 44.8 23.0 0.033 14.3 0.9 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI83728.1 - 9.3e-11 41.8 15.3 2.6e-06 27.5 0.6 5.2 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 AFI83728.1 - 1.6e-10 41.3 24.9 2.3e-05 24.8 0.3 5.8 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 AFI83728.1 - 1.9e-08 33.7 23.5 0.0083 15.9 0.0 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 AFI83728.1 - 2.2e-07 31.1 25.5 0.0094 16.2 4.8 6.7 4 1 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 AFI83728.1 - 1.9e-06 27.9 13.4 0.75 10.0 0.0 6.6 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 AFI83728.1 - 2.4e-05 24.6 14.5 0.026 14.9 0.2 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 AFI83728.1 - 7.7e-05 22.5 25.4 2.5 8.3 0.3 8.6 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 AFI83728.1 - 0.00061 20.0 11.4 0.28 11.7 0.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_18 PF13512.6 AFI83728.1 - 0.0028 17.8 16.7 0.45 10.6 0.8 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AFI83728.1 - 0.003 18.1 27.6 0.52 11.1 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 AFI83728.1 - 0.028 14.5 0.2 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 AFI83728.1 - 0.069 13.2 3.9 8.8 6.5 0.0 4.4 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat YvbH_ext PF11724.8 AFI83728.1 - 0.49 10.8 4.1 20 5.6 0.1 3.6 3 1 0 3 3 3 0 YvbH-like oligomerisation region HemY_N PF07219.13 AFI83728.1 - 1.7 8.8 9.9 0.5 10.6 0.2 3.2 4 1 0 4 4 3 0 HemY protein N-terminus TPR_10 PF13374.6 AFI83728.1 - 3.2 7.8 27.6 2.3 8.2 0.5 6.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 AFI83728.1 - 10 5.9 19.2 3.9 7.2 0.2 5.6 7 1 0 7 7 7 0 TPR repeat Aldolase_II PF00596.21 AFI83729.1 - 1.2e-32 113.4 0.4 1.4e-32 113.2 0.4 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FGE-sulfatase PF03781.16 AFI83730.1 - 2.4e-30 106.0 8.7 1.1e-29 103.8 8.7 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 AFI83730.1 - 6.5e-13 49.3 0.1 1.6e-12 48.1 0.1 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_31 PF13847.6 AFI83730.1 - 3.8e-12 46.3 0.0 6.6e-10 39.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83730.1 - 8.1e-10 38.8 0.0 2.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83730.1 - 4.7e-09 36.8 0.5 5.6e-07 30.2 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI83730.1 - 5.1e-08 33.5 0.1 1.5e-06 28.7 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83730.1 - 9.2e-08 32.7 0.2 6.8e-07 30.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 AFI83730.1 - 5.7e-05 22.3 0.0 0.0087 15.2 0.0 2.9 3 0 0 3 3 3 1 DREV methyltransferase Ubie_methyltran PF01209.18 AFI83730.1 - 0.011 15.1 0.1 0.081 12.2 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 AFI83730.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Aminotran_1_2 PF00155.21 AFI83731.1 - 4.5e-36 124.8 0.0 5e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2582 PF10771.9 AFI83732.1 - 6.3e-18 64.7 0.4 6.7e-18 64.6 0.4 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix domain (DUF2582) HTH_36 PF13730.6 AFI83732.1 - 0.0038 17.2 0.1 0.0057 16.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AFI83732.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_9 PF08221.11 AFI83732.1 - 0.069 13.3 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 AFI83732.1 - 0.097 12.5 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_26 PF13443.6 AFI83732.1 - 0.11 13.0 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3365 PF11845.8 AFI83733.1 - 3.5e-29 102.1 0.1 4.3e-29 101.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) DUF4030 PF13222.6 AFI83733.1 - 0.07 13.3 0.3 0.12 12.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4030) DNA_gyraseB PF00204.25 AFI83734.1 - 1.3e-39 135.5 0.0 2.2e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AFI83734.1 - 2e-21 75.9 0.5 4e-21 75.0 0.5 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AFI83734.1 - 3e-18 66.4 0.1 5.4e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AFI83734.1 - 2.4e-11 43.8 0.0 2.1e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 AFI83734.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_topoisoIV PF00521.20 AFI83735.1 - 4.1e-136 454.3 0.0 4.9e-136 454.0 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AFI83735.1 - 1.4e-07 30.9 0.0 0.0002 20.7 0.0 3.7 5 0 0 5 5 5 2 DNA gyrase C-terminal domain, beta-propeller DUF4890 PF16231.5 AFI83735.1 - 0.049 14.1 2.4 0.12 12.9 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) DUF3305 PF11749.8 AFI83736.1 - 7.9e-37 126.5 0.0 9.2e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3305) DUF3306 PF11748.8 AFI83737.1 - 5.6e-14 53.0 13.2 4.9e-12 46.8 4.6 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3306) Fer4 PF00037.27 AFI83738.1 - 5.1e-23 79.9 37.1 1.3e-07 31.1 2.9 4.8 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_6 PF12837.7 AFI83738.1 - 6.2e-20 70.4 43.4 7.8e-07 28.9 2.7 4.9 6 0 0 6 6 4 4 4Fe-4S binding domain Fer4_7 PF12838.7 AFI83738.1 - 9.4e-19 67.8 28.0 3.5e-08 33.9 9.3 3.7 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 AFI83738.1 - 7.8e-15 55.6 26.5 0.0033 18.3 0.2 4.7 4 1 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AFI83738.1 - 1.5e-14 53.8 31.2 6.5e-07 29.4 10.8 3.9 3 1 2 5 5 5 4 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI83738.1 - 6.9e-12 45.3 35.9 3.1e-05 24.0 11.4 3.8 3 2 1 4 4 4 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI83738.1 - 5.5e-11 41.9 41.5 0.00043 20.2 2.3 5.4 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_21 PF14697.6 AFI83738.1 - 1.9e-09 37.5 36.1 1.1e-05 25.5 6.3 3.9 2 1 3 5 5 5 4 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI83738.1 - 2.3e-08 34.4 28.6 0.0048 17.3 3.0 4.6 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AFI83738.1 - 2.3e-08 34.4 24.9 0.0055 17.2 4.1 4.8 5 0 0 5 5 4 4 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI83738.1 - 1.2e-07 31.7 41.8 0.001 19.4 2.6 5.1 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_15 PF13459.6 AFI83738.1 - 1.9e-05 25.3 20.3 0.023 15.5 0.6 4.6 4 0 0 4 4 4 2 4Fe-4S single cluster domain Fer4_3 PF12798.7 AFI83738.1 - 9.4e-05 23.1 57.3 0.026 15.4 6.4 5.1 6 0 0 6 6 4 4 4Fe-4S binding domain Fer4_13 PF13370.6 AFI83738.1 - 0.024 15.2 34.3 0.31 11.6 1.9 4.8 4 1 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AFI83738.1 - 1.9 8.7 27.4 0.13 12.5 7.8 3.8 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_19 PF06902.11 AFI83738.1 - 7 6.8 13.4 61 3.8 8.1 4.0 2 1 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Nitrate_red_del PF02613.15 AFI83739.1 - 2e-24 86.2 0.0 3.2e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Nitrate reductase delta subunit Molybdopterin PF00384.22 AFI83740.1 - 5.8e-59 200.2 0.8 7.6e-59 199.8 0.8 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI83740.1 - 3.9e-21 75.2 0.5 2.3e-20 72.7 0.0 2.5 3 0 0 3 3 3 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AFI83740.1 - 3.3e-11 43.0 0.9 7.1e-11 41.9 0.9 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AFI83740.1 - 0.0001 22.0 1.4 0.00026 20.7 1.4 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_7 PF12838.7 AFI83741.1 - 1.1e-14 54.7 20.0 1.6e-08 35.0 0.3 2.7 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.6 AFI83741.1 - 8e-12 45.2 18.9 4.2e-10 39.6 10.9 3.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI83741.1 - 1.9e-10 40.8 25.0 2.1e-06 27.8 3.4 2.9 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI83741.1 - 6.8e-10 38.9 30.5 1.4e-06 28.3 5.7 3.0 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AFI83741.1 - 4.4e-09 35.8 15.1 1.7e-07 30.7 2.4 5.7 6 0 0 6 6 6 2 4Fe-4S binding domain Fer4_2 PF12797.7 AFI83741.1 - 1.1e-08 34.6 31.6 4.9e-05 23.2 0.9 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_6 PF12837.7 AFI83741.1 - 8.2e-08 32.0 13.8 1.5e-06 28.0 2.2 4.3 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_21 PF14697.6 AFI83741.1 - 5.4e-05 23.2 31.2 0.011 15.9 2.8 3.4 2 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AFI83741.1 - 5.8e-05 23.7 40.9 0.0046 17.8 3.8 4.6 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 AFI83741.1 - 0.0027 18.1 13.5 0.02 15.4 3.3 4.0 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 AFI83741.1 - 0.0046 17.4 30.2 0.7 10.4 14.3 3.7 2 2 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AFI83741.1 - 0.12 13.1 0.3 0.12 13.1 0.3 4.2 3 2 0 3 3 3 0 4Fe-4S single cluster domain Fer4_16 PF13484.6 AFI83741.1 - 0.17 12.9 32.0 0.11 13.5 5.8 4.1 2 2 2 4 4 4 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AFI83741.1 - 3.6 8.2 34.5 0.71 10.5 5.5 4.4 3 1 0 4 4 4 0 4Fe-4S dicluster domain Ni_hydr_CYTB PF01292.20 AFI83743.1 - 3.2e-25 88.8 18.6 9e-23 80.8 11.6 2.8 2 1 1 3 3 3 2 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AFI83743.1 - 0.0018 18.8 5.9 0.0018 18.8 5.9 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4405) 7tm_7 PF08395.12 AFI83743.1 - 0.004 16.4 3.0 0.0074 15.5 1.5 2.0 2 1 0 2 2 2 1 7tm Chemosensory receptor Ndc1_Nup PF09531.10 AFI83743.1 - 0.012 14.3 0.3 0.016 13.9 0.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Holin_SPP1 PF04688.13 AFI83743.1 - 0.056 13.6 3.4 0.06 13.5 0.2 2.6 3 0 0 3 3 3 0 SPP1 phage holin Herpes_US9 PF06072.11 AFI83743.1 - 0.55 10.1 1.7 32 4.5 0.0 2.8 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF5367 PF17329.2 AFI83743.1 - 1.7 8.8 9.7 2.7 8.2 0.1 4.5 5 1 0 5 5 5 0 Family of unknown function (DUF5367) DUF2269 PF10027.9 AFI83743.1 - 3.4 7.7 21.1 3 7.9 0.1 4.1 4 1 0 4 4 4 0 Predicted integral membrane protein (DUF2269) Complex1_51K PF01512.17 AFI83744.1 - 5.5e-39 133.5 0.0 1.9e-38 131.7 0.0 1.9 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit 2Fe-2S_thioredx PF01257.19 AFI83744.1 - 1.4e-27 96.4 0.1 2.5e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NADH_4Fe-4S PF10589.9 AFI83744.1 - 1.2e-21 76.5 0.0 4.9e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AFI83744.1 - 3.2e-09 36.5 0.1 6.8e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 SLBB domain Molybdopterin PF00384.22 AFI83745.1 - 6.8e-96 321.9 0.0 8.7e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI83745.1 - 1.3e-24 86.3 0.0 2.6e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AFI83745.1 - 1e-16 60.6 0.9 1e-16 60.6 0.9 2.0 1 1 1 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_4 PF13510.6 AFI83745.1 - 6.9e-14 51.7 0.2 1.8e-13 50.3 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AFI83745.1 - 4e-09 36.3 0.6 1.3e-08 34.7 0.6 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AFI83745.1 - 3.5e-07 29.8 21.5 7.7e-06 25.5 4.1 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AFI83745.1 - 4.2e-07 30.0 9.2 4.2e-07 30.0 9.2 2.9 3 1 0 4 4 3 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AFI83745.1 - 7.2e-07 29.2 10.3 7.2e-07 29.2 10.3 2.5 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI83745.1 - 7.3e-05 23.3 31.5 8.9e-05 23.0 14.2 3.2 2 1 2 4 4 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI83745.1 - 8e-05 22.5 15.9 0.00096 19.1 3.6 3.3 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AFI83745.1 - 0.00023 21.2 20.7 0.016 15.3 0.9 3.0 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI83745.1 - 0.00041 20.7 8.0 0.00041 20.7 8.0 2.4 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 AFI83745.1 - 0.0012 19.6 4.2 0.2 12.5 0.4 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI83745.1 - 0.0021 18.0 2.1 0.0021 18.0 2.1 4.0 5 0 0 5 5 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 AFI83745.1 - 0.011 16.7 3.9 0.011 16.7 3.9 2.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain TPP_enzyme_M PF00205.22 AFI83745.1 - 0.045 13.5 0.0 0.67 9.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CDC48_N PF02359.18 AFI83745.1 - 0.13 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Fer4_13 PF13370.6 AFI83745.1 - 0.22 12.1 15.2 1.7 9.2 3.3 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AFI83745.1 - 0.55 10.4 13.3 0.31 11.2 2.3 2.8 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AFI83745.1 - 5.5 7.8 13.8 1.3e+02 3.4 13.8 2.7 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 AFI83745.1 - 9.3 6.9 23.8 0.055 14.0 12.6 3.0 3 1 1 4 4 2 0 4Fe-4S dicluster domain SurE PF01975.17 AFI83746.1 - 1.2e-53 181.8 0.0 1.4e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE PCMT PF01135.19 AFI83747.1 - 4.6e-60 203.0 0.0 5.7e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AFI83747.1 - 3.1e-06 27.8 0.0 5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83747.1 - 1.1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83747.1 - 7.1e-05 22.7 0.0 0.00013 21.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 AFI83747.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 AFI83747.1 - 0.0034 18.0 0.0 0.0076 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 AFI83747.1 - 0.004 16.6 0.0 0.036 13.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase GCD14 PF08704.10 AFI83747.1 - 0.037 13.7 0.0 0.079 12.6 0.0 1.5 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit NodS PF05401.11 AFI83747.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 AFI83747.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 AFI83747.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SNARE_assoc PF09335.11 AFI83748.1 - 1.4e-13 51.4 10.7 2.2e-12 47.5 9.2 2.2 1 1 1 2 2 2 2 SNARE associated Golgi protein FtsX PF02687.21 AFI83748.1 - 0.028 14.9 10.6 0.53 10.8 1.7 2.4 1 1 1 2 2 2 0 FtsX-like permease family Peptidase_M23 PF01551.22 AFI83750.1 - 1.2e-28 99.2 0.1 1.5e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 AFI83750.1 - 0.00029 20.6 0.2 0.00086 19.1 0.1 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 AFI83750.1 - 0.019 14.9 0.1 0.073 13.0 0.0 1.9 1 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 AFI83750.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AFI83750.1 - 0.096 12.4 0.2 3 7.6 0.0 2.1 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Gifsy-2 PF13856.6 AFI83750.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 1 0 1 1 1 0 ATP-binding sugar transporter from pro-phage PCRF PF03462.18 AFI83751.1 - 4.1e-55 186.6 0.3 4.1e-55 186.6 0.3 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AFI83751.1 - 6.6e-42 142.1 2.4 1.2e-41 141.3 2.4 1.4 1 0 0 1 1 1 1 RF-1 domain Ferritin PF00210.24 AFI83751.1 - 0.0031 17.4 1.4 0.0058 16.6 1.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain MIR PF02815.19 AFI83751.1 - 0.0042 17.0 0.2 0.038 13.8 0.0 2.1 1 1 1 2 2 2 1 MIR domain DUF2408 PF10303.9 AFI83751.1 - 0.2 12.2 4.9 1.1 9.8 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) ABC_tran_CTD PF16326.5 AFI83751.1 - 1.1 9.5 9.1 8.2 6.8 0.0 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain tRNA-synt_2 PF00152.20 AFI83752.1 - 6e-84 281.8 0.2 7.5e-84 281.5 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AFI83752.1 - 1.8e-15 56.7 0.0 3.6e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AFI83752.1 - 0.00016 21.2 0.7 0.089 12.3 0.3 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Phage_integrase PF00589.22 AFI83753.1 - 2.4e-44 151.1 0.2 3.6e-44 150.6 0.2 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 AFI83753.1 - 1.7e-19 70.1 0.9 4.3e-19 68.8 0.1 2.1 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 AFI83753.1 - 0.00024 21.4 0.6 0.003 17.8 0.0 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 AFI83753.1 - 0.012 15.7 0.7 0.6 10.2 0.7 2.4 1 1 0 1 1 1 0 Integrase Phage_integr_3 PF16795.5 AFI83753.1 - 0.045 13.7 0.3 0.36 10.7 0.0 2.3 2 1 0 2 2 2 0 Archaeal phage integrase DUF2192 PF09958.9 AFI83754.1 - 0.034 13.7 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) EF-hand_7 PF13499.6 AFI83756.1 - 0.039 14.4 0.8 0.07 13.6 0.3 1.7 2 0 0 2 2 2 0 EF-hand domain pair AKNA PF12443.8 AFI83756.1 - 0.077 13.7 0.3 0.99 10.1 0.0 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Mrr_cat PF04471.12 AFI83759.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease RHH_1 PF01402.21 AFI83760.1 - 0.0074 16.2 0.5 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family ParG PF09274.10 AFI83760.1 - 0.013 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 ParG HicB PF05534.12 AFI83760.1 - 0.049 13.5 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 HicB family RHH_5 PF07878.11 AFI83760.1 - 0.089 12.7 0.3 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Thioredoxin PF00085.20 AFI83761.1 - 4.2e-14 52.4 0.0 4.9e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AFI83761.1 - 0.00011 22.4 0.0 0.087 13.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 AFI83761.1 - 0.00045 20.6 0.0 0.00061 20.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 AFI83761.1 - 0.0093 16.4 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.6 AFI83761.1 - 0.0098 16.1 0.0 0.013 15.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 AFI83761.1 - 0.03 14.3 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF953 PF06110.11 AFI83761.1 - 0.16 11.6 0.2 0.35 10.5 0.2 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 AFI83761.1 - 0.19 11.7 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HTH_3 PF01381.22 AFI83763.1 - 4.6e-11 42.6 0.0 7.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix MqsA_antitoxin PF15731.5 AFI83763.1 - 2e-08 34.4 0.0 2.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_31 PF13560.6 AFI83763.1 - 9.3e-08 32.3 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AFI83763.1 - 3.1e-05 23.9 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 AFI83763.1 - 4.8e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_psq PF05225.16 AFI83763.1 - 0.0011 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 AFI83763.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI83763.1 - 0.0049 16.6 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain MerR_1 PF13411.6 AFI83763.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein Phage_CI_repr PF07022.13 AFI83763.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.6 1 1 1 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain DNA_ligase_OB_2 PF14743.6 AFI83764.1 - 6.2e-32 109.4 0.1 9.6e-32 108.8 0.1 1.3 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 AFI83764.1 - 2.1e-08 34.0 0.0 4.4e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.19 AFI83764.1 - 0.12 12.2 0.0 11 5.8 0.0 2.3 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Thioredoxin PF00085.20 AFI83765.1 - 5.1e-12 45.7 0.0 6.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AFI83765.1 - 0.0001 22.6 0.0 0.21 11.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 AFI83765.1 - 0.00052 20.4 0.0 0.0017 18.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 AFI83765.1 - 0.013 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 AFI83765.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 AFI83765.1 - 0.024 14.8 0.0 0.028 14.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.11 AFI83765.1 - 0.027 14.1 0.3 0.069 12.8 0.3 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF836 PF05768.14 AFI83765.1 - 0.14 12.6 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) YoeB_toxin PF06769.14 AFI83766.1 - 3.1e-40 136.1 0.8 3.5e-40 135.9 0.8 1.0 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system ParE_toxin PF05016.15 AFI83766.1 - 0.002 18.7 0.1 0.0021 18.6 0.1 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HigB-like_toxin PF05015.13 AFI83766.1 - 0.032 14.6 0.1 0.04 14.3 0.1 1.3 1 1 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB PhdYeFM_antitox PF02604.19 AFI83767.1 - 1e-21 76.5 0.1 1.2e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AFI83767.1 - 3.8e-05 23.7 0.1 4.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system SLT PF01464.20 AFI83768.1 - 2e-08 33.9 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain PepSY_TM PF03929.16 AFI83769.1 - 5.1e-41 141.2 8.2 6.4e-41 140.9 8.2 1.0 1 0 0 1 1 1 1 PepSY-associated TM region Ni_hydr_CYTB PF01292.20 AFI83769.1 - 0.00086 18.9 2.3 0.00086 18.9 2.3 2.7 3 0 0 3 3 3 1 Prokaryotic cytochrome b561 PepSY_TM_like_2 PF16357.5 AFI83769.1 - 0.081 12.9 7.8 3.6 7.5 2.5 3.2 2 1 1 3 3 3 0 Putative PepSY_TM-like DUF1430 PF07242.11 AFI83769.1 - 0.48 10.7 0.1 0.48 10.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) DHHC PF01529.20 AFI83769.1 - 4.2 7.5 4.9 9.8 6.3 1.4 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase TonB_dep_Rec PF00593.24 AFI83770.1 - 1.6e-41 143.7 14.0 1.6e-41 143.7 14.0 1.9 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI83770.1 - 1.5e-15 57.7 0.3 3.6e-15 56.4 0.3 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI83770.1 - 2.5e-11 43.2 3.0 3.3e-08 32.9 0.9 2.3 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family Phenol_MetA_deg PF13557.6 AFI83770.1 - 4.7 7.1 13.3 2.3 8.1 1.9 3.4 2 1 1 3 3 3 0 Putative MetA-pathway of phenol degradation HTH_18 PF12833.7 AFI83771.1 - 5e-24 84.4 0.0 1.5e-23 82.8 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AFI83771.1 - 1.7e-18 66.2 0.0 1.2e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4096 PF13340.6 AFI83772.1 - 2.8e-24 85.1 3.3 2.8e-24 85.1 3.3 1.9 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AFI83773.1 - 5.9e-18 65.0 0.7 6.7e-18 64.9 0.7 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI83773.1 - 4.6e-10 39.5 3.7 4.7e-08 32.9 3.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI83773.1 - 1.3e-06 28.2 0.1 1.6e-06 27.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AFI83773.1 - 2.2e-06 27.7 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Cellulase PF00150.18 AFI83773.1 - 0.047 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) YhhN PF07947.14 AFI83775.1 - 0.0038 16.9 0.2 0.005 16.5 0.2 1.1 1 0 0 1 1 1 1 YhhN family Glucan_synthase PF02364.15 AFI83775.1 - 0.027 12.7 2.4 0.033 12.4 2.4 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component YlaC PF10777.9 AFI83775.1 - 0.062 13.1 2.6 0.092 12.6 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC SpoIISA_toxin PF14171.6 AFI83775.1 - 0.088 12.5 4.3 0.13 11.9 4.3 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Pox_T4_N PF04491.12 AFI83775.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus DUF3420 PF11900.8 AFI83775.1 - 0.18 12.0 1.0 0.45 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DUF4191 PF13829.6 AFI83775.1 - 0.35 10.2 1.4 0.48 9.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3043 PF11241.8 AFI83775.1 - 1.7 8.6 3.1 2.5 8.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Methyltransf_11 PF08241.12 AFI83776.1 - 2.3e-17 63.4 0.0 4.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83776.1 - 2e-15 56.9 0.0 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83776.1 - 3e-15 56.7 0.0 5.6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83776.1 - 2.6e-13 50.5 0.0 5.4e-13 49.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83776.1 - 1e-11 44.9 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AFI83776.1 - 8.7e-10 38.3 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 AFI83776.1 - 4.8e-06 25.7 0.0 6.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 AFI83776.1 - 0.00018 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 AFI83776.1 - 0.00032 20.0 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 AFI83776.1 - 0.0021 17.2 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 AFI83776.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 AFI83776.1 - 0.019 13.5 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_5 PF01795.19 AFI83776.1 - 0.026 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Methyltransf_28 PF02636.17 AFI83776.1 - 0.027 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 AFI83776.1 - 0.034 14.2 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 AFI83776.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 AFI83776.1 - 0.074 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase RHH_1 PF01402.21 AFI83777.1 - 7.4e-07 28.9 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family PSK_trans_fac PF07704.11 AFI83777.1 - 0.0032 18.2 0.2 0.004 17.9 0.2 1.1 1 0 0 1 1 1 1 Rv0623-like transcription factor DUF4336 PF14234.6 AFI83777.1 - 0.035 13.3 0.5 0.038 13.2 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) DUF3323 PF11796.8 AFI83777.1 - 0.1 12.5 4.3 0.15 11.9 4.3 1.2 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF2270 PF10028.9 AFI83777.1 - 0.14 11.7 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) ParE_toxin PF05016.15 AFI83778.1 - 2.4e-13 50.5 0.0 2.6e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF3144 PF11342.8 AFI83780.1 - 6.4e-29 100.1 7.3 8.3e-29 99.7 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3144) DUF761 PF05553.11 AFI83780.1 - 0.1 12.1 6.0 5.2 6.7 0.1 3.4 2 1 1 3 3 3 0 Cotton fibre expressed protein Rep_2 PF01719.17 AFI83781.1 - 0.018 14.8 0.9 0.02 14.7 0.9 1.0 1 0 0 1 1 1 0 Plasmid replication protein Spermine_synth PF01564.17 AFI83782.1 - 5.3e-06 26.0 0.0 9.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 AFI83782.1 - 0.0002 22.0 0.0 0.00048 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83782.1 - 0.0017 18.2 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI83782.1 - 0.1 13.2 0.0 0.28 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 AFI83783.1 - 5.2e-68 228.9 0.0 6.5e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 AFI83783.1 - 5.6e-07 30.2 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83783.1 - 8.9e-07 28.8 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AFI83783.1 - 3.8e-06 26.2 0.0 5.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 AFI83783.1 - 4.7e-06 27.2 0.0 1.3e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI83783.1 - 2.7e-05 24.0 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AFI83783.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 AFI83783.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 AFI83783.1 - 0.13 13.0 0.0 0.3 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RIO1 PF01163.22 AFI83784.1 - 7.3e-43 146.4 0.2 9.4e-43 146.0 0.2 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AFI83784.1 - 3.9e-07 30.3 1.6 0.00089 19.2 0.2 2.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 AFI83784.1 - 6.8e-06 25.6 0.5 4.6e-05 22.9 0.5 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 AFI83784.1 - 0.0055 16.1 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.9 AFI83784.1 - 0.015 14.8 1.9 0.023 14.2 0.5 2.0 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Exo_endo_phos PF03372.23 AFI83785.1 - 1.8e-17 63.7 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0242 PF06785.11 AFI83785.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF294 PF03445.13 AFI83787.1 - 1.3e-47 161.1 0.0 2.4e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 DUF294_C PF10335.9 AFI83787.1 - 9.1e-43 145.5 0.3 1.5e-42 144.8 0.3 1.3 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain cNMP_binding PF00027.29 AFI83787.1 - 1.4e-13 50.7 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CBS PF00571.28 AFI83787.1 - 3.1e-13 49.9 1.7 7.2e-08 32.8 0.1 2.9 2 0 0 2 2 2 2 CBS domain GlnD_UR_UTase PF08335.11 AFI83787.1 - 0.006 16.7 0.1 0.016 15.3 0.1 1.8 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase RNase_T PF00929.24 AFI83788.1 - 1e-15 58.7 0.0 1.7e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease CAF1 PF04857.20 AFI83788.1 - 0.038 13.2 0.0 2.4 7.2 0.0 2.3 2 1 0 2 2 2 0 CAF1 family ribonuclease RNase_H_2 PF13482.6 AFI83788.1 - 0.052 13.5 0.0 0.087 12.8 0.0 1.6 1 1 0 1 1 1 0 RNase_H superfamily BCCT PF02028.17 AFI83789.1 - 2.8e-179 596.6 37.8 3.1e-179 596.5 37.8 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter CCDC53 PF10152.9 AFI83790.1 - 0.0055 17.1 0.0 0.0075 16.7 0.0 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex FlaC_arch PF05377.11 AFI83790.1 - 0.013 15.9 2.1 0.023 15.1 2.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) BicD PF09730.9 AFI83790.1 - 0.019 13.4 0.2 0.026 13.0 0.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D FlxA PF14282.6 AFI83790.1 - 0.051 13.6 0.3 0.086 12.8 0.3 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF1192 PF06698.11 AFI83790.1 - 0.11 12.5 3.3 0.19 11.8 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.15 AFI83790.1 - 0.15 11.9 3.5 0.33 10.7 3.5 1.5 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 AFI83790.1 - 0.16 12.6 0.9 0.28 11.8 0.9 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF3584 PF12128.8 AFI83790.1 - 0.35 8.3 0.8 0.47 7.9 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 AFI83790.1 - 0.38 11.3 4.8 0.57 10.7 4.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region IFP_35_N PF07334.13 AFI83790.1 - 0.59 10.2 3.7 2.2 8.4 3.7 1.8 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Med21 PF11221.8 AFI83790.1 - 0.68 10.2 3.3 1.1 9.5 3.3 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex CASP_C PF08172.12 AFI83790.1 - 1.8 7.9 4.3 2.8 7.2 4.3 1.2 1 0 0 1 1 1 0 CASP C terminal ABC_tran_CTD PF16326.5 AFI83790.1 - 2.1 8.6 7.4 3.7 7.9 7.4 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Usp PF00582.26 AFI83791.1 - 3.5e-13 50.3 0.2 4.5e-13 49.9 0.2 1.2 1 0 0 1 1 1 1 Universal stress protein family CdhD PF03599.16 AFI83791.1 - 0.029 13.1 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit AA_kinase PF00696.28 AFI83791.1 - 0.044 13.4 0.2 5.1 6.6 0.0 2.1 1 1 1 2 2 2 0 Amino acid kinase family SQS_PSY PF00494.19 AFI83793.1 - 4e-47 160.9 0.3 5.1e-47 160.6 0.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RmuC PF02646.16 AFI83794.1 - 1.6e-96 322.9 1.9 1.6e-96 322.9 1.9 2.0 2 0 0 2 2 2 1 RmuC family DUF4808 PF16066.5 AFI83794.1 - 0.014 15.9 1.9 0.017 15.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4808) DUF948 PF06103.11 AFI83794.1 - 0.017 15.4 6.1 0.19 12.0 2.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BCAS2 PF05700.11 AFI83794.1 - 0.023 14.4 10.2 0.063 13.0 10.1 1.8 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DinB_2 PF12867.7 AFI83794.1 - 0.024 15.2 1.7 7.7 7.0 0.1 2.5 1 1 1 2 2 2 0 DinB superfamily Glu_cys_ligase PF04262.14 AFI83794.1 - 0.039 12.6 4.7 1 7.9 4.8 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase DUF1043 PF06295.12 AFI83794.1 - 0.041 13.9 18.5 0.07 13.1 2.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) BPD_transp_2 PF02653.16 AFI83794.1 - 0.076 12.2 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component ApoO PF09769.9 AFI83794.1 - 0.082 12.9 2.9 4.5 7.3 0.0 3.2 2 1 0 2 2 2 0 Apolipoprotein O ApoLp-III PF07464.11 AFI83794.1 - 0.089 12.9 16.5 1.6 8.8 11.2 2.7 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) NAD_kinase PF01513.21 AFI83794.1 - 0.093 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-NAD kinase DUF3584 PF12128.8 AFI83794.1 - 0.19 9.2 17.5 0.33 8.4 17.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rep_1 PF01446.17 AFI83794.1 - 0.2 11.1 5.8 0.67 9.4 0.5 3.0 3 0 0 3 3 3 0 Replication protein DLP_helical PF18709.1 AFI83794.1 - 0.77 8.9 14.7 6.3 5.9 12.3 2.4 2 0 0 2 2 2 0 Dynamin-like helical domain Laminin_II PF06009.12 AFI83794.1 - 2.5 8.1 16.9 0.37 10.8 5.7 3.2 2 1 1 3 3 3 0 Laminin Domain II Phage_GPO PF05929.11 AFI83794.1 - 2.8 7.5 12.2 5 6.7 12.2 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase dCache_1 PF02743.18 AFI83794.1 - 4.3 7.0 9.2 6.8 6.4 8.5 1.7 1 1 0 1 1 1 0 Cache domain Cob_adeno_trans PF01923.18 AFI83794.1 - 4.4 7.4 8.8 28 4.8 0.5 3.1 2 1 1 3 3 3 0 Cobalamin adenosyltransferase FRB_dom PF08771.11 AFI83794.1 - 5.7 7.4 8.9 2.2 8.8 3.8 2.5 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain DUF4446 PF14584.6 AFI83794.1 - 7.7 6.5 8.3 8.9 6.3 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HAD_2 PF13419.6 AFI83795.1 - 4.8e-32 111.5 0.0 5.6e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI83795.1 - 6.4e-13 49.5 0.2 1.9e-11 44.6 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI83795.1 - 4.9e-11 42.5 0.0 1.6e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 AFI83795.1 - 1.3e-09 38.8 0.0 2e-09 38.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AFI83795.1 - 0.063 13.0 0.4 8.6 6.0 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AFI83795.1 - 0.19 11.9 0.0 2.4 8.3 0.0 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 AFI83796.1 - 4.1e-22 78.8 0.0 5.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI83796.1 - 5.5e-18 65.4 0.0 1.6e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83796.1 - 1.3e-15 57.9 0.0 2.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI83796.1 - 7.8e-15 55.0 0.0 9.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI83796.1 - 8.2e-14 52.2 0.0 1.4e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AFI83796.1 - 8.4e-09 35.1 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 AFI83796.1 - 7e-07 28.9 0.0 9.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 AFI83796.1 - 1.4e-06 27.8 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 AFI83796.1 - 2.3e-05 24.4 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AFI83796.1 - 4.3e-05 23.1 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AFI83796.1 - 8.1e-05 22.3 0.0 0.0001 22.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 AFI83796.1 - 0.00011 21.3 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AFI83796.1 - 0.0031 17.5 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AFI83796.1 - 0.0039 16.8 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 AFI83796.1 - 0.014 15.7 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DREV PF05219.12 AFI83796.1 - 0.045 12.9 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase TPMT PF05724.11 AFI83796.1 - 0.063 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Amidohydro_1 PF01979.20 AFI83797.1 - 1.5e-69 234.9 0.2 1.8e-69 234.7 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AFI83797.1 - 2.6e-24 86.5 3.2 5.3e-23 82.2 0.3 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 AFI83797.1 - 6.4e-07 29.0 0.0 3.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase TatD_DNase PF01026.21 AFI83797.1 - 0.01 15.3 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 0 TatD related DNase IF-2B PF01008.17 AFI83798.1 - 1.5e-79 267.1 0.1 1.9e-79 266.9 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1961 PF09224.11 AFI83798.1 - 0.072 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) adh_short PF00106.25 AFI83799.1 - 1.9e-29 102.6 0.0 2.4e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AFI83799.1 - 8.4e-24 84.4 0.0 1.1e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 AFI83799.1 - 5.1e-06 26.5 0.0 6.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AFI83799.1 - 0.0011 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AFI83799.1 - 0.0023 17.1 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 AFI83799.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 KR domain APH PF01636.23 AFI83800.1 - 3.5e-06 27.1 0.6 5.8e-06 26.4 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2783 PF10932.8 AFI83800.1 - 0.37 10.5 2.5 56 3.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2783) NMN_transporter PF04973.12 AFI83801.1 - 2.2e-47 161.3 28.4 2.6e-47 161.1 28.4 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter Phage_holin_3_3 PF16083.5 AFI83801.1 - 0.0058 16.7 0.1 0.0058 16.7 0.1 2.8 2 1 1 3 3 3 1 LydA holin phage, holin superfamily III Ykof PF07615.11 AFI83802.1 - 4.8e-07 30.2 0.0 5.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 YKOF-related Family Thiamine_BP PF01910.17 AFI83802.1 - 0.0057 16.6 0.0 0.0062 16.4 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein DUF4615 PF15393.6 AFI83802.1 - 0.053 14.1 0.0 0.054 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) TonB_dep_Rec PF00593.24 AFI83803.1 - 1.6e-31 110.7 46.3 1.7e-31 110.7 45.7 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83803.1 - 3.1e-19 69.5 1.7 1.3e-18 67.5 0.6 2.4 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Sugarporin_N PF11471.8 AFI83803.1 - 0.22 11.5 0.1 0.43 10.6 0.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Polyketide_cyc2 PF10604.9 AFI83804.1 - 2.9e-26 92.4 0.1 1.2e-25 90.5 0.1 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AFI83804.1 - 0.002 18.3 0.0 0.0027 17.9 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LysR_substrate PF03466.20 AFI83805.1 - 8.7e-40 136.3 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AFI83805.1 - 5.9e-17 61.4 0.3 1.1e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF3300 PF11737.8 AFI83805.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) MarR_2 PF12802.7 AFI83805.1 - 0.097 12.6 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 MarR family HTH_30 PF13556.6 AFI83805.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain TauE PF01925.19 AFI83807.1 - 6.1e-46 157.0 36.4 7e-46 156.8 36.4 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE PAPS_reduct PF01507.19 AFI83808.1 - 1.2e-42 145.9 0.0 1.5e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.19 AFI83809.1 - 2.3e-63 213.3 0.0 2.8e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family GTP_EFTU PF00009.27 AFI83810.1 - 7.6e-44 149.6 0.0 1.1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AFI83810.1 - 2.2e-07 30.9 0.1 1.9e-05 24.7 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AFI83810.1 - 2.7e-05 24.5 0.1 6.8e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 AFI83810.1 - 0.016 15.4 0.1 3.1 8.0 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D3 PF03143.17 AFI83810.1 - 0.02 15.2 0.2 0.043 14.1 0.2 1.6 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain SRPRB PF09439.10 AFI83810.1 - 0.023 14.1 0.1 0.69 9.3 0.0 2.3 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit ATP-sulfurylase PF01747.17 AFI83810.1 - 0.036 13.5 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 ATP-sulfurylase RAMA PF18755.1 AFI83810.1 - 0.038 14.4 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated RMI1_C PF16099.5 AFI83810.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold EAL PF00563.20 AFI83812.1 - 1.6e-46 158.7 0.2 2e-46 158.4 0.2 1.1 1 0 0 1 1 1 1 EAL domain BPL_C PF02237.17 AFI83812.1 - 1.1 9.2 3.0 33 4.5 0.1 2.8 3 0 0 3 3 3 0 Biotin protein ligase C terminal domain UDG PF03167.19 AFI83813.1 - 1.5e-12 47.8 0.0 1.7e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF3465 PF11948.8 AFI83814.1 - 4.2e-51 172.1 0.2 4.9e-51 171.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3465) DUF4131 PF13567.6 AFI83814.1 - 0.0023 17.6 0.0 0.0044 16.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) tRNA_anti-codon PF01336.25 AFI83814.1 - 0.079 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FAD_binding_4 PF01565.23 AFI83815.1 - 0.0068 16.2 0.0 0.0068 16.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NIR_SIR PF01077.22 AFI83816.1 - 1.4e-53 180.6 0.0 1.3e-41 141.7 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AFI83816.1 - 7.3e-33 112.2 0.0 8.3e-16 57.6 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF934 PF06073.12 AFI83817.1 - 4.6e-37 126.2 0.0 6.2e-37 125.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF934) Metallophos PF00149.28 AFI83818.1 - 2e-14 54.6 2.2 2.5e-14 54.2 1.7 1.6 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AFI83818.1 - 2.3e-07 31.2 0.1 1.5e-05 25.2 0.2 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 AFI83818.1 - 0.094 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase PTS_EIIB PF00367.20 AFI83818.1 - 0.16 11.5 0.3 0.31 10.6 0.3 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB DMRL_synthase PF00885.19 AFI83819.1 - 2.1e-57 192.9 0.4 2.4e-57 192.7 0.4 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase NusB PF01029.18 AFI83820.1 - 2.4e-31 108.7 0.1 3e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 NusB family AIRS PF00586.24 AFI83821.1 - 7.5e-24 84.2 0.1 1.6e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AFI83821.1 - 2.1e-07 31.2 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain PgpA PF04608.13 AFI83822.1 - 1.3e-52 177.6 9.0 1.5e-52 177.4 9.0 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A EcsB PF05975.12 AFI83822.1 - 7.4e-05 21.8 2.5 8.6e-05 21.6 2.5 1.2 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB GtrA PF04138.14 AFI83822.1 - 0.78 10.0 6.7 1.8 8.8 6.7 1.8 1 1 0 1 1 1 0 GtrA-like protein PfkB PF00294.24 AFI83823.1 - 2.5e-40 138.6 0.0 3.2e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DNA_pol_A_exo1 PF01612.20 AFI83824.1 - 8.1e-37 126.6 1.1 3.9e-36 124.4 0.7 2.0 2 0 0 2 2 2 1 3'-5' exonuclease HRDC PF00570.23 AFI83824.1 - 3.8e-18 65.2 1.8 3.8e-18 65.2 1.8 2.2 2 0 0 2 2 2 1 HRDC domain Slx4 PF09494.10 AFI83824.1 - 0.045 13.7 0.3 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Slx4 endonuclease RasGEF_N_2 PF14663.6 AFI83824.1 - 0.083 13.3 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1992 PF09350.10 AFI83824.1 - 0.13 12.4 2.2 0.25 11.6 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1992) Abhydrolase_1 PF00561.20 AFI83825.1 - 3.2e-13 49.9 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AFI83825.1 - 3.2e-11 44.3 0.0 5.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 AFI83825.1 - 0.00086 19.5 0.1 0.0023 18.1 0.1 1.7 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 AFI83825.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AFI83825.1 - 0.0025 16.6 0.0 0.0062 15.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 AFI83825.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 AFI83825.1 - 0.026 14.3 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1057 PF06342.12 AFI83825.1 - 0.14 11.2 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF836 PF05768.14 AFI83826.1 - 4.9e-16 58.9 0.1 5.6e-16 58.7 0.1 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 AFI83826.1 - 0.00081 19.4 0.0 0.001 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Glutaredoxin PF00462.24 AFI83826.1 - 0.038 14.2 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF1223 PF06764.11 AFI83826.1 - 0.042 13.9 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) MoCF_biosynth PF00994.24 AFI83827.1 - 4.4e-33 114.0 0.1 5.4e-33 113.7 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF4115 PF13464.6 AFI83827.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) CsoS2_M PF12288.8 AFI83827.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region OmpA PF00691.20 AFI83828.1 - 2e-23 82.6 0.2 7e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 OmpA family Gly-zipper_Omp PF13488.6 AFI83828.1 - 5.2e-09 36.0 19.9 7.6e-09 35.4 19.9 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 AFI83828.1 - 2.1e-06 27.3 22.3 3.2e-06 26.8 22.3 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 AFI83828.1 - 5.4e-05 23.0 20.9 8.2e-05 22.4 20.9 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF3482 PF11981.8 AFI83828.1 - 0.00045 19.7 3.8 0.00074 19.0 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) TraT PF05818.12 AFI83828.1 - 0.0032 17.2 0.3 0.0037 17.0 0.3 1.3 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Nup188_C PF18378.1 AFI83828.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Gly-zipper_OmpA PF13436.6 AFI83828.1 - 0.16 11.8 22.3 0.28 11.0 22.3 1.3 1 0 0 1 1 1 0 Glycine-zipper domain Bacteriocin_IIc PF10439.9 AFI83828.1 - 0.66 10.1 11.3 1.2 9.3 11.3 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 AFI83828.1 - 0.74 10.1 8.9 2.3 8.5 1.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1269) DUF1043 PF06295.12 AFI83828.1 - 3 7.8 5.9 0.37 10.8 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) SpoU_methylase PF00588.19 AFI83829.1 - 1.5e-40 138.6 0.0 2.8e-40 137.8 0.0 1.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AFI83829.1 - 2.4e-18 66.2 0.0 8.7e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding DUF2183 PF09949.9 AFI83829.1 - 0.18 12.1 0.0 0.92 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Ribosomal_S6 PF01250.17 AFI83830.1 - 1.5e-26 92.5 0.0 1.9e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 BTD PF09270.10 AFI83830.1 - 0.085 13.1 0.2 0.11 12.8 0.2 1.4 1 1 0 1 1 1 0 Beta-trefoil DNA-binding domain Ribosomal_S18 PF01084.20 AFI83831.1 - 2.1e-25 88.7 0.1 2.7e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 DUF2232 PF09991.9 AFI83832.1 - 8.9e-05 21.8 40.0 0.00082 18.6 40.0 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) Ribosomal_L9_C PF03948.14 AFI83833.1 - 2.3e-24 85.7 0.5 4.5e-24 84.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AFI83833.1 - 2.5e-19 68.6 0.7 2.5e-19 68.6 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Cytochrom_C_2 PF01322.20 AFI83833.1 - 0.06 14.3 0.1 0.06 14.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C' DUF2175 PF09943.9 AFI83833.1 - 3.7 7.9 5.1 14 6.1 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DnaB_C PF03796.15 AFI83834.1 - 5e-120 399.6 0.0 6.5e-120 399.2 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AFI83834.1 - 1.3e-34 118.3 0.0 2.7e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AFI83834.1 - 2.7e-13 49.9 0.0 4.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AFI83834.1 - 1.1e-05 24.9 0.0 0.00023 20.6 0.0 2.5 2 1 1 3 3 3 1 KaiC AAA PF00004.29 AFI83834.1 - 7.5e-05 23.2 0.0 0.00029 21.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AFI83834.1 - 0.00024 21.3 0.0 0.0025 18.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AFI83834.1 - 0.00071 19.9 0.0 0.0021 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AFI83834.1 - 0.007 16.1 0.1 0.3 10.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AFI83834.1 - 0.0089 16.1 0.0 0.1 12.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.10 AFI83834.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 AFI83834.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AFI83834.1 - 0.054 13.5 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AFI83834.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 AFI83834.1 - 0.098 13.0 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Ala_racemase_N PF01168.20 AFI83835.1 - 1.7e-59 201.1 0.1 2.2e-59 200.8 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AFI83835.1 - 1e-41 141.6 0.1 1.7e-41 140.9 0.1 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain ATPase PF06745.13 AFI83836.1 - 2.6e-20 72.8 0.3 1.1e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 AFI83836.1 - 1.2e-15 57.6 0.1 4.2e-15 55.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 AFI83836.1 - 2.2e-12 46.5 5.5 3.3e-12 45.9 5.5 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 AFI83836.1 - 2.6e-08 33.7 0.0 6.5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 AFI83836.1 - 1.8e-06 27.5 0.1 4.1e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Lon_C PF05362.13 AFI83836.1 - 2.8e-06 27.0 0.3 7.2e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Rad51 PF08423.11 AFI83836.1 - 3.8e-06 26.4 0.4 1.5e-05 24.4 0.4 1.9 1 1 0 1 1 1 1 Rad51 AAA_24 PF13479.6 AFI83836.1 - 1.2e-05 25.1 0.0 8.2e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain PAXNEB PF05625.11 AFI83836.1 - 5.9e-05 22.4 0.3 0.0001 21.6 0.3 1.3 1 0 0 1 1 1 1 PAXNEB protein AAA_22 PF13401.6 AFI83836.1 - 0.00013 22.3 0.3 0.00035 20.9 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI83836.1 - 0.00058 20.3 1.6 0.0029 18.0 1.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain RecA PF00154.21 AFI83836.1 - 0.00059 19.4 0.2 0.0016 17.9 0.1 1.6 1 1 1 2 2 2 1 recA bacterial DNA recombination protein AAA PF00004.29 AFI83836.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 AFI83836.1 - 0.0013 17.4 0.1 0.65 8.5 0.0 2.5 1 1 1 2 2 2 2 GvpD gas vesicle protein NACHT PF05729.12 AFI83836.1 - 0.0052 16.7 0.6 0.015 15.2 0.6 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 AFI83836.1 - 0.015 15.7 0.6 0.066 13.5 0.2 2.2 2 1 0 2 2 2 0 AAA domain CobU PF02283.16 AFI83836.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_14 PF13173.6 AFI83836.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AFI83836.1 - 0.033 13.5 0.1 0.055 12.7 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 AFI83836.1 - 0.037 13.2 0.5 0.087 12.0 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 AFI83836.1 - 0.043 13.2 0.5 0.23 10.9 0.5 2.2 1 1 1 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 AFI83836.1 - 0.056 12.7 0.0 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 AFI83836.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AFI83836.1 - 0.067 13.1 0.2 0.6 10.0 0.0 2.3 1 1 0 2 2 2 0 NTPase Isochorismatase PF00857.20 AFI83836.1 - 0.071 13.3 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Isochorismatase family zf-RING_10 PF16685.5 AFI83836.1 - 0.11 12.6 0.3 0.19 11.9 0.3 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 AFI83836.1 - 0.15 12.1 0.8 0.27 11.3 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon ABC_tran PF00005.27 AFI83836.1 - 0.3 11.6 2.0 0.34 11.4 0.3 2.0 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 AFI83836.1 - 0.33 10.7 1.1 0.61 9.9 0.3 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain PilZ PF07238.14 AFI83837.1 - 3.5e-09 36.9 0.0 4.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 PilZ domain UPF0093 PF03653.13 AFI83838.1 - 1.8e-51 174.2 11.8 2e-51 174.1 11.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) CopD PF05425.13 AFI83838.1 - 7.1e-07 29.6 2.8 7.1e-07 29.6 2.8 1.9 1 1 1 2 2 2 1 Copper resistance protein D Coiled-coil_56 PF09813.9 AFI83838.1 - 0.021 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Sdh_cyt PF01127.22 AFI83838.1 - 3.9 7.5 11.2 0.054 13.5 1.9 2.1 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit BON PF04972.17 AFI83839.1 - 1.5e-29 102.1 0.4 1e-13 51.3 0.1 2.2 2 0 0 2 2 2 2 BON domain AcetylCoA_hyd_C PF13336.6 AFI83839.1 - 0.019 14.9 0.1 0.048 13.6 0.1 1.6 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain UPF0102 PF02021.17 AFI83840.1 - 2.9e-29 101.1 0.0 3.4e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 AFI83840.1 - 0.00029 21.3 0.0 0.00051 20.5 0.0 1.4 1 1 0 1 1 1 1 Nuclease-related domain Mrr_cat PF04471.12 AFI83840.1 - 0.005 16.9 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF4143 PF13635.6 AFI83840.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) NucS PF01939.16 AFI83840.1 - 0.023 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS DUF234 PF03008.14 AFI83840.1 - 0.1 13.1 0.0 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 Archaea bacterial proteins of unknown function LppC PF04348.13 AFI83841.1 - 2.4e-103 346.8 10.4 2.8e-103 346.6 10.4 1.0 1 0 0 1 1 1 1 LppC putative lipoprotein Peripla_BP_6 PF13458.6 AFI83841.1 - 1.2e-13 51.5 0.4 2.7e-13 50.3 0.1 1.7 2 0 0 2 2 2 1 Periplasmic binding protein ANF_receptor PF01094.28 AFI83841.1 - 9.5e-06 24.9 0.1 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region TP_methylase PF00590.20 AFI83842.1 - 9.9e-29 100.8 0.5 1.8e-28 100.0 0.2 1.5 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TetR_C_7 PF14246.6 AFI83843.1 - 6.9e-11 42.2 2.1 2.8e-09 37.0 0.7 2.2 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AFI83843.1 - 5.3e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 AFI83843.1 - 1.9e-07 31.4 0.1 3.8e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_2 PF08361.11 AFI83843.1 - 4.9e-05 23.4 0.2 0.00015 21.9 0.2 1.9 1 1 1 2 2 2 1 MAATS-type transcriptional repressor, C-terminal region TetR_C_13 PF16925.5 AFI83843.1 - 9.5e-05 22.3 0.0 0.00018 21.4 0.0 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AFI83843.1 - 9.9e-05 22.5 0.3 9.9e-05 22.5 0.3 1.9 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_29 PF17938.1 AFI83843.1 - 0.00017 21.7 0.8 0.00024 21.2 0.2 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 AFI83843.1 - 0.00066 20.0 3.9 0.00083 19.6 0.9 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 AFI83843.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_15 PF17918.1 AFI83843.1 - 0.0064 17.2 0.8 0.0064 17.2 0.8 2.2 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 AFI83843.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 AFI83843.1 - 0.025 15.3 0.3 0.1 13.4 0.1 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HlyD_3 PF13437.6 AFI83844.1 - 3.8e-09 37.2 0.0 0.0029 18.3 0.0 3.8 2 2 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI83844.1 - 4.9e-05 23.1 0.0 0.0019 18.0 0.0 3.0 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 AFI83844.1 - 9e-05 21.8 1.8 0.025 13.8 0.0 2.9 3 0 0 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ACR_tran PF00873.19 AFI83845.1 - 1.5e-161 539.4 1.4 1.7e-161 539.2 1.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI83845.1 - 8.3e-08 31.5 11.6 8.3e-08 31.5 11.6 3.1 4 0 0 4 4 4 1 MMPL family SecD_SecF PF02355.16 AFI83845.1 - 7.9e-07 28.6 11.0 7.9e-07 28.6 11.0 2.3 2 0 0 2 2 2 1 Protein export membrane protein ZT_dimer PF16916.5 AFI83845.1 - 0.0028 17.7 0.1 0.68 10.1 0.1 3.1 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter AMP-binding_C PF13193.6 AFI83845.1 - 0.058 14.4 0.3 0.69 10.9 0.0 3.0 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain Imm47 PF15573.6 AFI83845.1 - 0.3 10.6 1.5 0.87 9.0 0.2 2.2 2 0 0 2 2 2 0 Immunity protein 47 Cytochrom_C_2 PF01322.20 AFI83846.1 - 7.5e-09 36.5 2.6 3.6e-08 34.3 2.6 1.9 1 1 0 1 1 1 1 Cytochrome C' Alpha-E PF04168.12 AFI83846.1 - 0.00046 20.1 0.2 0.00059 19.7 0.2 1.3 1 1 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. DDE_Tnp_1_3 PF13612.6 AFI83847.1 - 1.9e-77 258.6 0.0 2.7e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI83847.1 - 7.9e-23 81.2 0.1 1.1e-21 77.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI83847.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_ISL3 PF01610.17 AFI83848.1 - 1.2e-61 208.5 1.4 2e-61 207.8 1.4 1.3 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 AFI83848.1 - 6.1e-11 42.8 1.1 6.1e-11 42.8 1.1 2.0 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 AFI83848.1 - 0.0019 17.6 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HemX PF04375.14 AFI83848.1 - 0.017 14.4 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Zn-ribbon_8 PF09723.10 AFI83848.1 - 0.021 14.9 0.2 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-IS66 PF13005.7 AFI83848.1 - 0.056 13.9 2.9 0.16 12.4 2.9 1.9 1 1 0 1 1 1 0 zinc-finger binding domain of transposase IS66 rve_3 PF13683.6 AFI83848.1 - 0.14 11.9 0.4 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Integrase core domain Osteopontin PF00865.18 AFI83848.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Osteopontin MraZ PF02381.18 AFI83849.1 - 1.5e-38 130.6 0.0 1.3e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like DUF2375 PF09558.10 AFI83849.1 - 0.0013 18.7 0.0 0.065 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2375) Methyltransf_5 PF01795.19 AFI83850.1 - 2e-114 382.3 0.0 2.4e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 AFI83850.1 - 0.0013 18.6 0.0 0.54 10.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 AFI83850.1 - 0.0087 16.7 0.0 0.099 13.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 AFI83850.1 - 0.071 13.2 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase FtsL PF04999.13 AFI83851.1 - 2.6e-25 88.3 0.3 2.9e-25 88.1 0.3 1.0 1 0 0 1 1 1 1 Cell division protein FtsL DivIC PF04977.15 AFI83851.1 - 0.0024 17.6 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Septum formation initiator Transpeptidase PF00905.22 AFI83852.1 - 4.9e-74 249.3 0.0 6e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AFI83852.1 - 6.8e-22 78.7 0.0 2.2e-20 73.8 0.0 2.2 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Mur_ligase_M PF08245.12 AFI83853.1 - 8.3e-56 189.0 0.7 2.3e-55 187.6 0.2 1.9 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AFI83853.1 - 1.1e-20 73.6 0.0 5.3e-20 71.5 0.0 2.2 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AFI83853.1 - 0.00076 19.8 0.1 0.004 17.4 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 AFI83854.1 - 8.2e-50 169.5 0.0 1.6e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AFI83854.1 - 2.5e-13 50.1 0.0 1.7e-12 47.4 0.0 2.4 2 1 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AFI83854.1 - 7.8e-10 39.0 0.2 3.5e-09 36.8 0.2 2.2 1 1 0 1 1 1 1 Mur ligase family, catalytic domain Glycos_transf_4 PF00953.21 AFI83855.1 - 1.7e-35 122.3 13.6 1.7e-35 122.3 13.6 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 AFI83855.1 - 0.038 13.5 2.3 0.038 13.5 2.3 3.0 3 0 0 3 3 3 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Mur_ligase_M PF08245.12 AFI83856.1 - 5.9e-28 98.2 0.0 1.1e-27 97.3 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AFI83856.1 - 5e-07 29.9 0.0 1.5e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DAO PF01266.24 AFI83856.1 - 0.00011 22.0 0.0 0.0028 17.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 AFI83856.1 - 0.00027 21.2 0.0 0.0013 19.0 0.0 2.2 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 AFI83856.1 - 0.00041 20.5 0.0 0.0045 17.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AFI83856.1 - 0.0026 17.1 0.4 0.21 10.8 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 AFI83856.1 - 0.0044 17.2 0.0 0.86 9.7 0.0 3.1 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 AFI83856.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 AFI83856.1 - 0.045 14.2 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 AFI83856.1 - 0.07 13.7 0.3 0.89 10.2 0.0 3.0 2 2 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FTSW_RODA_SPOVE PF01098.19 AFI83857.1 - 4.5e-103 345.0 30.0 5.3e-103 344.8 30.0 1.0 1 0 0 1 1 1 1 Cell cycle protein Glyco_tran_28_C PF04101.16 AFI83858.1 - 9.2e-44 149.4 0.5 1.4e-43 148.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 AFI83858.1 - 9.7e-42 142.3 0.1 1.6e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_transf_4 PF13439.6 AFI83858.1 - 2e-05 24.7 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI83858.1 - 0.00018 22.0 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 AFI83858.1 - 0.00032 20.3 0.1 0.00056 19.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI83858.1 - 0.04 14.3 0.1 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 UDPGT PF00201.18 AFI83858.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Mur_ligase_M PF08245.12 AFI83859.1 - 6.9e-29 101.2 0.0 9.8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AFI83859.1 - 2.1e-28 98.5 0.5 2.1e-28 98.5 0.5 1.7 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AFI83859.1 - 2.3e-22 79.1 0.0 6.6e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain F420_oxidored PF03807.17 AFI83859.1 - 0.0011 19.5 0.4 0.0037 17.8 0.4 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_trans_4_5 PF16994.5 AFI83859.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 MurB_C PF02873.16 AFI83860.1 - 2.7e-30 104.9 0.0 6.4e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 AFI83860.1 - 8.9e-20 70.9 0.1 1.5e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Dala_Dala_lig_C PF07478.13 AFI83861.1 - 1.1e-59 201.4 0.0 1.5e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AFI83861.1 - 9e-20 71.1 0.2 6.6e-19 68.3 0.2 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp_3 PF02655.14 AFI83861.1 - 1.7e-08 34.6 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AFI83861.1 - 1.1e-07 31.6 0.0 4e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AFI83861.1 - 3.8e-07 29.8 0.0 3.8e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 AFI83861.1 - 3.1e-05 23.6 0.0 6.3e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 AFI83861.1 - 0.00054 19.8 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 AFI83861.1 - 0.0018 17.6 0.0 1.9 7.7 0.0 2.8 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 AFI83861.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp FtsQ PF03799.15 AFI83862.1 - 3.1e-20 73.1 0.1 5.9e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Cell division protein FtsQ POTRA_1 PF08478.10 AFI83862.1 - 7.5e-16 58.2 0.1 1.9e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 POTRA domain, FtsQ-type Neurensin PF14927.6 AFI83862.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Neurensin Sigma_reg_N PF13800.6 AFI83862.1 - 0.15 12.4 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal FtsA PF14450.6 AFI83863.1 - 1.1e-37 128.6 1.6 1.1e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AFI83863.1 - 2e-33 114.6 2.2 2e-33 114.6 0.2 2.2 3 0 0 3 3 2 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 AFI83863.1 - 3.7e-14 52.3 1.0 7.7e-13 48.0 0.5 2.3 2 0 0 2 2 2 1 MreB/Mbl protein EutA PF06277.11 AFI83863.1 - 2.1e-06 26.9 1.6 5.4e-06 25.5 0.3 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 AFI83863.1 - 3.5e-05 23.0 0.4 0.0075 15.3 0.0 3.1 3 0 0 3 3 3 1 Type IV pilus assembly protein PilM; HSP70 PF00012.20 AFI83863.1 - 0.00091 17.5 1.4 0.27 9.4 0.1 2.5 3 0 0 3 3 3 2 Hsp70 protein DDR PF08841.10 AFI83863.1 - 0.0018 17.4 0.2 0.0034 16.4 0.2 1.5 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Actin PF00022.19 AFI83863.1 - 0.0068 15.1 0.3 0.14 10.8 0.0 2.6 2 1 0 3 3 3 1 Actin Hydantoinase_A PF01968.18 AFI83863.1 - 0.043 13.1 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase SrfB PF07520.11 AFI83863.1 - 0.044 11.7 0.1 0.061 11.2 0.1 1.1 1 0 0 1 1 1 0 Virulence factor SrfB IstB_IS21 PF01695.17 AFI83863.1 - 0.14 11.9 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Tubulin PF00091.25 AFI83864.1 - 3.9e-40 138.2 1.6 6.1e-40 137.5 0.9 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AFI83864.1 - 1.1e-38 131.4 3.5 4.6e-38 129.4 3.5 2.2 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 AFI83864.1 - 0.019 14.9 0.6 0.059 13.3 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 AFI83864.1 - 0.13 11.8 1.1 1.9 8.0 0.1 2.5 2 1 1 3 3 3 0 NmrA-like family Tubulin_2 PF13809.6 AFI83864.1 - 0.67 9.1 8.6 6.8 5.8 3.9 2.7 1 1 1 2 2 2 0 Tubulin like LpxC PF03331.13 AFI83865.1 - 2.7e-107 358.3 0.0 3.1e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase DciA PF05258.12 AFI83866.1 - 3e-13 50.0 0.2 4.7e-13 49.4 0.2 1.3 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA Arc_PepC PF06819.11 AFI83866.1 - 0.023 14.8 0.1 0.042 14.0 0.1 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain FTA4 PF13093.6 AFI83866.1 - 0.032 14.1 1.3 0.18 11.7 0.2 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3251 PF11622.8 AFI83866.1 - 0.14 11.8 3.3 1.3 8.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) Peptidase_M23 PF01551.22 AFI83867.1 - 4e-33 113.5 1.2 5.8e-33 113.0 1.2 1.2 1 0 0 1 1 1 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 AFI83867.1 - 0.0019 18.0 0.2 0.0062 16.3 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like SecA_DEAD PF07517.14 AFI83868.1 - 5.2e-132 439.5 1.2 1.1e-131 438.5 1.2 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 AFI83868.1 - 6.9e-70 235.2 7.1 1.2e-69 234.4 5.5 2.2 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AFI83868.1 - 9.9e-41 138.9 0.1 3.4e-40 137.2 0.1 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AFI83868.1 - 1.3e-10 41.0 6.9 2.2e-10 40.3 6.9 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 AFI83868.1 - 0.0011 18.8 0.0 0.0053 16.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Baculo_gp41 PF04700.12 AFI83868.1 - 0.0036 17.1 0.1 0.0088 15.8 0.1 1.6 1 0 0 1 1 1 1 Structural glycoprotein p40/gp41 conserved region Helicase_C PF00271.31 AFI83868.1 - 0.032 14.6 1.3 0.11 12.8 0.0 2.5 2 0 0 2 2 2 0 Helicase conserved C-terminal domain ArgJ PF01960.18 AFI83869.1 - 1.4e-142 474.9 5.9 1.6e-142 474.7 5.9 1.0 1 0 0 1 1 1 1 ArgJ family LPD7 PF18821.1 AFI83869.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 DUF3549 PF12069.8 AFI83870.1 - 2.1e-103 346.0 0.1 2.3e-103 345.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) Putative_PNPOx PF01243.20 AFI83871.1 - 4.9e-11 42.7 0.0 7.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pep_deformylase PF01327.21 AFI83872.1 - 2.9e-48 163.5 0.0 3.3e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase DUF4792 PF16040.5 AFI83872.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4792) 2OG-FeII_Oxy_3 PF13640.6 AFI83873.1 - 4.6e-22 78.7 0.2 1.1e-21 77.6 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 AFI83873.1 - 5.5e-17 62.2 0.3 1.2e-16 61.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 AFI83873.1 - 0.065 13.6 0.1 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Gate PF07670.14 AFI83874.1 - 4.9e-12 46.1 23.3 1.5e-08 34.9 4.3 3.7 3 2 0 3 3 3 2 Nucleoside recognition DEAD PF00270.29 AFI83875.1 - 6.5e-47 159.5 0.1 2.5e-46 157.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI83875.1 - 2.1e-31 108.5 0.2 9.3e-30 103.2 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AFI83875.1 - 1.1e-21 76.6 0.0 4.1e-21 74.7 0.0 2.1 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 AFI83875.1 - 2.1e-06 27.8 0.0 7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AFI83875.1 - 0.00013 22.4 0.3 0.0035 17.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 AFI83875.1 - 0.001 18.5 0.2 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF410 PF04190.13 AFI83875.1 - 0.0023 17.8 0.1 0.0038 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) AAA_30 PF13604.6 AFI83875.1 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain GTP_cyclohydro2 PF00925.20 AFI83875.1 - 0.0089 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 GTP cyclohydrolase II UvrA_inter PF17760.1 AFI83875.1 - 0.0094 16.0 0.2 0.033 14.2 0.1 2.0 2 0 0 2 2 2 1 UvrA interaction domain Form_Nir_trans PF01226.17 AFI83876.1 - 7.3e-79 264.4 25.3 8.3e-79 264.3 25.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Dodecin PF07311.12 AFI83877.1 - 2.1e-28 98.4 1.1 2.3e-28 98.2 1.1 1.0 1 0 0 1 1 1 1 Dodecin Endopep_inhib PF16800.5 AFI83877.1 - 0.092 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor Ysc84 PF04366.12 AFI83878.1 - 5.9e-11 42.2 0.2 1.2e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF1134 PF06577.12 AFI83878.1 - 0.00048 19.9 1.0 0.00063 19.5 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1134) DUF1741 PF08427.10 AFI83878.1 - 0.00078 19.2 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) ABC_tran PF00005.27 AFI83879.1 - 1.3e-43 148.8 0.0 2e-20 73.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AFI83879.1 - 9.1e-25 86.5 6.7 1.9e-22 79.1 3.5 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AFI83879.1 - 2.4e-14 53.9 10.5 0.00056 19.8 0.0 4.8 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI83879.1 - 6.9e-07 28.9 7.5 0.34 10.3 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 AFI83879.1 - 3.5e-06 26.9 0.4 0.0042 16.8 0.2 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AFI83879.1 - 5e-06 26.9 0.3 0.096 13.1 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_29 PF13555.6 AFI83879.1 - 1.2e-05 25.0 0.2 0.21 11.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AFI83879.1 - 3.9e-05 23.6 0.0 0.1 12.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 AFI83879.1 - 4.8e-05 23.4 0.2 0.42 10.7 0.0 3.9 5 0 0 5 5 4 1 AAA domain AAA_28 PF13521.6 AFI83879.1 - 6.1e-05 23.3 0.1 0.64 10.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 AFI83879.1 - 6.6e-05 23.1 0.2 0.33 11.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 AFI83879.1 - 8.7e-05 22.5 0.4 0.091 12.7 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 AFI83879.1 - 0.00011 22.6 0.3 0.096 13.1 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AFI83879.1 - 0.00012 22.1 0.3 0.59 10.0 0.0 3.1 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_15 PF13175.6 AFI83879.1 - 0.00013 21.8 7.1 0.083 12.6 2.3 3.4 2 1 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.17 AFI83879.1 - 0.00037 20.6 1.4 0.25 11.4 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 AFI83879.1 - 0.00047 20.2 0.1 1 9.5 0.3 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 AFI83879.1 - 0.00058 20.4 0.0 1.8 9.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 AFI83879.1 - 0.00086 18.4 1.6 0.25 10.3 0.1 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 AFI83879.1 - 0.0012 18.3 0.0 4.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 AFI83879.1 - 0.0013 18.1 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 AFI83879.1 - 0.0014 18.9 1.7 0.17 12.2 0.1 3.2 2 2 1 3 3 2 1 AAA domain ATPase_2 PF01637.18 AFI83879.1 - 0.002 18.1 0.4 4.2 7.2 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 AFI83879.1 - 0.0029 17.6 0.5 0.28 11.2 0.1 2.8 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AFI83879.1 - 0.0043 17.5 0.0 0.45 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 AFI83879.1 - 0.0066 16.5 1.5 1.6 8.7 0.0 3.2 3 0 0 3 3 3 1 Dynamin family Roc PF08477.13 AFI83879.1 - 0.017 15.4 0.0 0.95 9.7 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 AFI83879.1 - 0.029 14.1 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 AFI83879.1 - 0.044 13.6 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase GcpE PF04551.14 AFI83879.1 - 0.056 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 GcpE protein AAA_5 PF07728.14 AFI83879.1 - 0.058 13.4 0.2 20 5.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 AFI83879.1 - 0.067 13.4 0.2 11 6.3 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 AFI83879.1 - 0.069 12.7 0.7 1 8.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 AFI83879.1 - 0.079 12.9 0.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 AFI83879.1 - 0.082 12.5 0.1 3.3 7.3 0.2 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 AFI83879.1 - 0.083 12.2 0.3 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family BRE1 PF08647.11 AFI83879.1 - 0.093 12.8 6.1 0.19 11.8 6.1 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SL4P PF17618.2 AFI83879.1 - 0.11 12.5 0.3 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein ATP-synt_ab PF00006.25 AFI83879.1 - 0.12 12.0 0.4 7.6 6.1 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 AFI83879.1 - 0.12 12.1 0.8 0.48 10.1 0.0 2.4 3 0 0 3 3 2 0 IstB-like ATP binding protein T2SSE PF00437.20 AFI83879.1 - 0.13 11.3 1.0 0.28 10.2 0.0 2.1 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.6 AFI83879.1 - 0.15 11.8 0.2 23 4.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 AFI83879.1 - 0.15 11.8 3.6 3.7 7.3 0.0 2.7 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_23 PF13476.6 AFI83879.1 - 0.16 12.4 16.7 0.22 12.0 0.0 3.3 2 1 1 3 3 2 0 AAA domain MukB PF04310.12 AFI83879.1 - 0.19 11.5 1.2 13 5.5 0.0 2.8 3 0 0 3 3 2 0 MukB N-terminal ATP_bind_1 PF03029.17 AFI83879.1 - 0.21 11.3 4.5 2.1 8.1 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 AFI83879.1 - 0.26 10.8 1.1 9.8 5.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain GrpE PF01025.19 AFI83879.1 - 1.2 8.8 5.8 19 4.9 3.9 2.4 2 0 0 2 2 2 0 GrpE NTPase_1 PF03266.15 AFI83879.1 - 7.2 6.5 10.3 0.4 10.6 0.3 3.5 5 0 0 5 5 3 0 NTPase Spore_IV_A PF09547.10 AFI83879.1 - 9 5.1 7.6 23 3.7 0.3 3.0 2 1 1 3 3 3 0 Stage IV sporulation protein A (spore_IV_A) GIY-YIG PF01541.24 AFI83880.1 - 6.4e-14 52.0 0.2 7.3e-14 51.8 0.2 1.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 AFI83880.1 - 0.0028 18.2 0.1 0.0032 18.0 0.1 1.1 1 0 0 1 1 1 1 T5orf172 domain SelR PF01641.18 AFI83881.1 - 2.7e-55 185.6 0.8 3.1e-55 185.5 0.8 1.0 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.9 AFI83881.1 - 0.0018 17.2 0.2 0.081 11.8 0.0 2.0 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 AFI83881.1 - 0.0039 17.4 1.0 0.0075 16.5 1.0 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37e PF01907.19 AFI83881.1 - 0.056 13.6 0.9 0.056 13.6 0.9 2.1 2 0 0 2 2 2 0 Ribosomal protein L37e SBP_bac_3 PF00497.20 AFI83882.1 - 4.2e-75 252.0 2.3 6e-40 137.0 0.0 2.7 3 0 0 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 HATPase_c PF02518.26 AFI83882.1 - 5.6e-31 107.3 0.4 1.6e-30 105.9 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AFI83882.1 - 1.9e-20 73.1 2.6 4.1e-20 72.0 0.7 2.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 AFI83882.1 - 6.2e-20 71.0 1.0 1.6e-19 69.7 0.2 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AFI83882.1 - 3.9e-06 26.7 0.0 8.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lig_chan-Glu_bd PF10613.9 AFI83882.1 - 0.00012 22.3 0.0 1.1 9.5 0.0 3.9 2 2 0 2 2 2 2 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 AFI83882.1 - 0.0017 18.0 0.6 1.5 8.3 0.1 2.8 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein PAS_9 PF13426.7 AFI83882.1 - 0.0081 16.4 0.0 0.03 14.6 0.0 2.1 1 0 0 1 1 1 1 PAS domain Inj_translocase PF16928.5 AFI83882.1 - 0.03 13.8 0.6 11 5.4 0.0 3.2 3 0 0 3 3 3 0 DNA/protein translocase of phage P22 injectosome Response_reg PF00072.24 AFI83883.1 - 1.3e-31 109.1 0.1 2.8e-31 108.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AFI83883.1 - 1.7e-19 70.3 1.7 4.2e-19 69.0 1.7 1.7 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AFI83883.1 - 9.6e-18 64.2 0.0 6.2e-17 61.6 0.1 2.4 2 0 0 2 2 2 1 HD domain PHTB1_C PF14728.6 AFI83883.1 - 0.0086 15.2 1.5 0.013 14.6 1.5 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus UDG PF03167.19 AFI83884.1 - 1.2e-25 90.3 0.1 1.9e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Thioredoxin_11 PF18078.1 AFI83884.1 - 0.066 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain ABC_tran PF00005.27 AFI83885.1 - 2.4e-45 154.4 2.9 9.4e-22 78.0 0.0 3.5 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 AFI83885.1 - 6e-29 99.9 5.0 6e-29 99.9 5.0 3.6 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 AFI83885.1 - 6.3e-19 68.9 3.8 0.0002 21.2 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI83885.1 - 2.6e-10 40.1 3.2 0.0066 15.9 0.0 4.3 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AFI83885.1 - 7.3e-07 29.7 8.3 0.00017 22.0 0.6 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 AFI83885.1 - 2.4e-06 27.2 0.4 0.048 13.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 AFI83885.1 - 1.5e-05 25.5 0.4 0.3 11.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain KAP_NTPase PF07693.14 AFI83885.1 - 1.6e-05 24.3 0.4 0.011 15.0 0.0 2.8 2 2 0 2 2 2 2 KAP family P-loop domain RsgA_GTPase PF03193.16 AFI83885.1 - 3.3e-05 23.8 2.2 0.034 14.1 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 AFI83885.1 - 5.1e-05 23.3 0.0 0.21 11.7 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA PF00004.29 AFI83885.1 - 0.00015 22.2 0.0 0.18 12.2 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AFI83885.1 - 0.00024 21.7 21.5 0.11 13.0 0.0 4.3 4 0 0 4 4 4 2 AAA domain DUF815 PF05673.13 AFI83885.1 - 0.00045 19.5 0.0 0.89 8.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ABC_tran_CTD PF16326.5 AFI83885.1 - 0.00051 20.2 13.0 0.00051 20.2 13.0 3.4 3 0 0 3 3 3 1 ABC transporter C-terminal domain AAA_22 PF13401.6 AFI83885.1 - 0.00079 19.7 1.9 2.7 8.3 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 AFI83885.1 - 0.0023 18.2 2.4 1.6 8.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 AFI83885.1 - 0.0025 18.2 0.3 2.5 8.5 0.0 3.2 3 1 0 3 3 2 1 RNA helicase NTPase_1 PF03266.15 AFI83885.1 - 0.0051 16.7 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 NTPase MeaB PF03308.16 AFI83885.1 - 0.0054 15.8 6.0 0.29 10.1 0.0 3.0 4 0 0 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 AFI83885.1 - 0.0057 16.3 0.1 1.4 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 AFI83885.1 - 0.012 15.6 1.0 3.4 7.6 0.0 3.3 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 AFI83885.1 - 0.017 14.8 1.7 4 7.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 AFI83885.1 - 0.028 14.1 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 AFI83885.1 - 0.032 13.4 0.0 7.6 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 AFI83885.1 - 0.053 13.2 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 AFI83885.1 - 0.06 12.9 0.0 13 5.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD_C PF13361.6 AFI83885.1 - 0.071 12.5 0.1 0.071 12.5 0.1 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Dynamin_N PF00350.23 AFI83885.1 - 0.078 13.0 3.2 34 4.4 0.1 4.0 4 0 0 4 4 4 0 Dynamin family Thymidylate_kin PF02223.17 AFI83885.1 - 0.085 12.5 1.6 1 9.0 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase TsaE PF02367.17 AFI83885.1 - 0.12 12.3 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AFI83885.1 - 0.18 11.8 1.1 11 6.0 0.0 3.5 4 1 0 4 4 2 0 AAA domain AAA_15 PF13175.6 AFI83885.1 - 0.89 9.2 10.2 15 5.1 0.2 4.1 3 1 1 4 4 4 0 AAA ATPase domain DUF4201 PF13870.6 AFI83885.1 - 2.6 7.8 16.7 4.5 7.0 8.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ABC_tran PF00005.27 AFI83886.1 - 8.5e-52 175.3 2.4 8.7e-26 91.1 0.1 3.6 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AFI83886.1 - 5.5e-19 69.1 12.0 2.8e-07 30.7 0.9 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 AFI83886.1 - 2.2e-16 59.9 12.1 2.2e-16 59.9 12.1 3.7 4 0 0 4 4 2 1 ABC transporter C-terminal domain ABC_tran_Xtn PF12848.7 AFI83886.1 - 6.7e-12 45.3 18.6 1.1e-10 41.3 0.9 3.7 2 1 1 3 3 3 2 ABC transporter SMC_N PF02463.19 AFI83886.1 - 1.3e-11 44.4 2.6 0.00014 21.4 0.2 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AFI83886.1 - 4.5e-08 32.7 0.1 0.0052 16.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AFI83886.1 - 1.2e-07 31.8 0.4 0.0043 17.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 AFI83886.1 - 1.6e-07 31.4 0.0 0.029 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 AFI83886.1 - 1.7e-07 31.8 7.7 0.00012 22.5 0.1 3.3 3 1 1 4 4 3 2 AAA ATPase domain AAA_15 PF13175.6 AFI83886.1 - 8.9e-07 28.9 9.1 0.068 12.9 0.0 4.4 4 1 1 5 5 5 2 AAA ATPase domain AAA_30 PF13604.6 AFI83886.1 - 1.5e-05 24.8 0.0 0.038 13.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AFI83886.1 - 3.9e-05 24.0 0.0 0.5 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 AFI83886.1 - 4.2e-05 24.0 0.0 0.2 12.1 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 AFI83886.1 - 5.1e-05 22.6 0.1 0.17 11.1 0.1 3.3 3 0 0 3 3 3 2 Zeta toxin ATP-synt_ab PF00006.25 AFI83886.1 - 0.00012 21.8 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 AFI83886.1 - 0.00014 20.9 0.3 0.21 10.6 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 AFI83886.1 - 0.0002 21.0 0.0 0.36 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AFI83886.1 - 0.00021 21.9 0.1 0.045 14.3 0.0 4.8 5 1 0 5 5 3 2 AAA domain NACHT PF05729.12 AFI83886.1 - 0.00037 20.4 3.8 0.23 11.4 0.0 3.3 2 1 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 AFI83886.1 - 0.00038 20.6 0.3 1.4 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 AFI83886.1 - 0.0007 19.9 0.1 0.47 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AFI83886.1 - 0.0012 18.6 0.2 2.2 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 AFI83886.1 - 0.0016 18.4 0.1 2.6 8.1 0.1 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AFI83886.1 - 0.0022 18.5 0.2 1.1 9.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AFI83886.1 - 0.0025 17.0 0.6 1.1 8.4 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.13 AFI83886.1 - 0.0036 16.5 0.1 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Roc PF08477.13 AFI83886.1 - 0.0051 17.0 1.8 2.6 8.3 0.0 3.5 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 AFI83886.1 - 0.0052 17.1 7.7 0.21 11.9 0.1 4.0 3 2 0 3 3 2 1 AAA domain AAA_7 PF12775.7 AFI83886.1 - 0.0055 16.2 1.9 2.2 7.8 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 AFI83886.1 - 0.0064 16.2 0.3 4.3 7.0 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein Rad17 PF03215.15 AFI83886.1 - 0.007 16.3 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 AFI83886.1 - 0.0096 15.8 3.7 0.86 9.5 0.0 3.5 3 0 0 3 3 3 1 NTPase ATPase_2 PF01637.18 AFI83886.1 - 0.013 15.4 0.8 0.96 9.3 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 AFI83886.1 - 0.018 14.7 1.0 2.6 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 AFI83886.1 - 0.023 14.7 4.9 2.9 7.9 0.0 3.3 3 1 0 3 3 2 0 Dynamin family PduV-EutP PF10662.9 AFI83886.1 - 0.032 14.0 0.2 3.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 AFI83886.1 - 0.033 14.2 0.5 6.3 6.8 0.0 3.6 3 1 0 3 3 3 0 AAA domain TsaE PF02367.17 AFI83886.1 - 0.042 13.9 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gtr1_RagA PF04670.12 AFI83886.1 - 0.059 12.7 0.3 6.8 6.0 0.0 2.9 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region Ploopntkinase3 PF18751.1 AFI83886.1 - 0.095 12.6 0.1 6 6.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 AFI83886.1 - 0.096 12.3 0.1 12 5.4 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 AFI83886.1 - 0.19 11.8 9.4 0.68 10.0 0.0 4.0 5 0 0 5 5 3 0 Helicase HerA, central domain CCDC-167 PF15188.6 AFI83886.1 - 4.3 7.7 10.0 0.19 12.1 1.7 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Cytochrom_C PF00034.21 AFI83887.1 - 0.00045 21.3 0.0 0.056 14.6 0.0 2.4 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AFI83887.1 - 0.03 14.6 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Haem_bd PF14376.6 AFI83887.1 - 0.059 13.3 0.1 0.18 11.7 0.1 1.6 1 1 1 2 2 2 0 Haem-binding domain DUF4197 PF13852.6 AFI83888.1 - 6.8e-80 267.5 0.5 8e-80 267.3 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4197) MR_MLE_C PF13378.6 AFI83888.1 - 0.043 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like CdiA_C PF18451.1 AFI83888.1 - 0.057 13.6 0.2 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Polyoma_coat2 PF00761.20 AFI83888.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 Polyomavirus coat protein Ribosomal_L22 PF00237.19 AFI83888.1 - 0.076 13.3 0.1 0.24 11.7 0.0 1.8 1 1 1 2 2 2 0 Ribosomal protein L22p/L17e CSD PF00313.22 AFI83889.1 - 1.5e-29 101.6 0.3 1.7e-29 101.5 0.3 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AFI83889.1 - 0.0098 15.6 0.3 0.013 15.2 0.3 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 AFI83889.1 - 0.038 13.9 0.0 0.06 13.2 0.0 1.4 1 1 0 1 1 1 0 Rho termination factor, RNA-binding domain Iron_traffic PF04362.14 AFI83890.1 - 5.2e-42 141.4 0.0 5.6e-42 141.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking HhH-GPD PF00730.25 AFI83891.1 - 7.4e-17 61.8 0.0 1.7e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 AFI83891.1 - 4.9e-11 42.6 0.0 1.5e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 AFI83891.1 - 7.5e-06 25.6 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Whib PF02467.16 AFI83891.1 - 0.0059 17.2 3.1 0.73 10.5 0.5 3.1 3 0 0 3 3 3 1 Transcription factor WhiB EndIII_4Fe-2S PF10576.9 AFI83891.1 - 0.057 13.8 7.3 0.11 12.9 7.3 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HHH_8 PF14716.6 AFI83891.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain TPR_6 PF13174.6 AFI83891.1 - 0.15 12.8 0.1 2.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_5 PF14520.6 AFI83891.1 - 0.19 12.4 0.0 0.42 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain AsmA PF05170.14 AFI83892.1 - 1.2e-82 278.7 34.0 1.6e-82 278.2 34.0 1.2 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 AFI83892.1 - 9.7e-28 97.2 20.0 5.6e-26 91.5 5.7 3.6 2 2 1 3 3 3 2 AsmA-like C-terminal region DUF748 PF05359.11 AFI83892.1 - 0.7 10.0 9.6 0.51 10.5 0.5 4.5 3 3 3 6 6 6 0 Domain of Unknown Function (DUF748) CSN5_C PF18323.1 AFI83892.1 - 1.8 9.5 6.2 5.2 8.0 0.1 3.3 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF21 PF01595.20 AFI83894.1 - 1.9e-46 158.0 10.1 2.7e-46 157.5 10.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AFI83894.1 - 1.4e-18 66.6 0.0 2.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AFI83894.1 - 4.6e-10 39.8 0.1 5.1e-05 23.6 0.0 3.0 2 0 0 2 2 2 2 CBS domain Cytochrom_C_asm PF01578.20 AFI83895.1 - 4.7e-33 114.8 21.5 6.3e-33 114.4 21.5 1.3 1 1 0 1 1 1 1 Cytochrome C assembly protein PufQ PF05398.11 AFI83895.1 - 0.093 12.9 1.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 PufQ cytochrome subunit SRP54 PF00448.22 AFI83896.1 - 4e-75 251.8 1.7 7.3e-75 250.9 1.7 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AFI83896.1 - 6.9e-35 119.6 5.4 6.9e-35 119.6 5.4 3.4 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 AFI83896.1 - 9.1e-23 80.3 0.8 9.1e-23 80.3 0.8 2.5 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 AFI83896.1 - 8.3e-07 29.1 0.0 3.7e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AFI83896.1 - 3.3e-06 27.4 0.0 3.5e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AFI83896.1 - 6.8e-06 25.5 0.0 1.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AFI83896.1 - 0.00013 21.8 0.8 0.00029 20.6 0.2 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 AFI83896.1 - 0.0019 17.7 1.3 0.039 13.4 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 AFI83896.1 - 0.0025 18.2 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain 6PF2K PF01591.18 AFI83896.1 - 0.0029 17.0 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 AFI83896.1 - 0.0044 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Peptidase_C23 PF05379.11 AFI83896.1 - 0.0044 17.1 0.0 3.9 7.7 0.0 2.8 2 0 0 2 2 2 1 Carlavirus endopeptidase DnaB_C PF03796.15 AFI83896.1 - 0.0052 16.2 0.2 0.012 14.9 0.2 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain APS_kinase PF01583.20 AFI83896.1 - 0.009 15.9 0.0 0.037 13.9 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase PIF1 PF05970.14 AFI83896.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_24 PF13479.6 AFI83896.1 - 0.016 15.0 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AFI83896.1 - 0.018 14.6 0.2 0.057 13.0 0.2 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AFI83896.1 - 0.02 15.1 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 AFI83896.1 - 0.021 14.5 0.2 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase TPP_enzyme_M PF00205.22 AFI83896.1 - 0.033 13.9 0.2 9.1 6.0 0.1 2.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ABC_tran PF00005.27 AFI83896.1 - 0.082 13.4 0.1 0.83 10.2 0.0 2.5 3 1 0 3 3 2 0 ABC transporter NACHT PF05729.12 AFI83896.1 - 0.087 12.7 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 NACHT domain AAA_31 PF13614.6 AFI83896.1 - 0.1 12.5 1.5 0.23 11.4 0.2 2.2 2 1 0 2 2 2 0 AAA domain Adaptin_binding PF10199.9 AFI83896.1 - 0.11 13.1 1.0 21 5.7 0.4 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF2075 PF09848.9 AFI83896.1 - 0.12 11.6 0.1 0.27 10.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 AFI83896.1 - 0.14 12.3 1.0 0.94 9.6 0.3 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase ArsA_ATPase PF02374.15 AFI83896.1 - 0.27 10.4 4.5 0.8 8.8 0.1 2.9 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_25 PF13481.6 AFI83896.1 - 0.55 9.8 4.1 12 5.5 4.1 2.6 1 1 0 1 1 1 0 AAA domain Mcm10 PF09332.11 AFI83896.1 - 1.1 8.7 3.7 3.2 7.1 3.7 1.7 1 1 0 1 1 1 0 Mcm10 replication factor Ribosomal_S16 PF00886.19 AFI83897.1 - 3.6e-26 91.0 0.1 4.3e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RimM PF01782.18 AFI83898.1 - 7.4e-23 80.6 0.0 1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AFI83898.1 - 5.1e-11 42.5 3.0 8.2e-10 38.6 0.3 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 AFI83898.1 - 0.08 13.2 0.2 0.39 11.0 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2171) HisG_C PF08029.11 AFI83898.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 HisG, C-terminal domain tRNA_m1G_MT PF01746.21 AFI83899.1 - 8.4e-65 218.1 0.0 9.7e-65 217.9 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L19 PF01245.20 AFI83900.1 - 4.3e-50 168.3 1.7 4.8e-50 168.1 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 Phage_integrase PF00589.22 AFI83901.1 - 5e-51 172.9 0.2 1.1e-50 171.8 0.1 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AFI83901.1 - 1.8e-19 69.8 5.4 3.6e-19 68.8 1.6 2.6 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AFI83901.1 - 1.7e-08 34.8 2.5 4.6e-08 33.4 0.2 2.6 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain DUF3435 PF11917.8 AFI83901.1 - 0.0064 15.5 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) 7TMR-DISMED2 PF07696.11 AFI83901.1 - 0.087 12.9 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 DUF520 PF04461.13 AFI83902.1 - 8.1e-64 214.6 5.7 9.1e-64 214.4 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) DinI PF06183.13 AFI83902.1 - 0.004 17.5 1.5 0.024 15.0 0.3 2.2 2 1 0 2 2 2 1 DinI-like family Thioredoxin_2 PF13098.6 AFI83903.1 - 5.4e-27 94.4 0.0 7.9e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 AFI83903.1 - 1.6e-13 49.9 0.0 2.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 AFI83903.1 - 4.1e-07 30.0 0.1 0.0019 18.0 0.0 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AFI83903.1 - 5.5e-07 29.9 0.2 0.024 14.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 AFI83903.1 - 0.02 14.9 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain DUF1507 PF07408.11 AFI83903.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Metallophos_2 PF12850.7 AFI83904.1 - 5.3e-11 43.0 0.3 4.8e-10 39.9 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AFI83904.1 - 7.8e-11 42.8 0.0 1.5e-10 41.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MTP18 PF10558.9 AFI83904.1 - 0.0092 16.0 0.2 0.043 13.8 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) PriA_C PF18074.1 AFI83904.1 - 0.074 13.9 0.2 0.16 12.8 0.2 1.5 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Pro_isomerase PF00160.21 AFI83905.1 - 1e-49 168.8 2.3 1.2e-49 168.6 2.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_1c PF00749.21 AFI83906.1 - 1.3e-106 356.1 0.0 2e-106 355.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AFI83906.1 - 7.3e-52 175.7 0.0 1.1e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 AFI83907.1 - 7e-134 445.9 0.0 9e-134 445.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AFI83907.1 - 5.5e-19 68.4 5.6 1.1e-18 67.4 2.9 2.7 3 0 0 3 3 3 1 DALR domain tRNA-synt_1g PF09334.11 AFI83907.1 - 2.6e-16 59.4 0.3 4.8e-07 28.9 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AFI83907.1 - 2.2e-08 32.9 0.0 2e-05 23.1 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AFI83907.1 - 5.3e-06 25.6 0.2 0.001 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Mut7-C PF01927.16 AFI83907.1 - 0.0031 17.6 0.1 0.0058 16.7 0.1 1.4 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF4473 PF14747.6 AFI83907.1 - 0.051 14.1 0.1 6.1 7.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4473) DUF5615 PF18480.1 AFI83907.1 - 0.069 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) HDOD PF08668.12 AFI83907.1 - 0.078 12.5 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 HDOD domain tRNA-synt_1c PF00749.21 AFI83907.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1d PF00750.19 AFI83907.1 - 0.13 11.2 0.1 0.3 10.0 0.1 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (R) Ribosomal_S11 PF00411.19 AFI83907.1 - 0.14 12.6 0.0 2.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein S11 Acetate_kinase PF00871.17 AFI83908.1 - 2.4e-114 382.1 0.0 2.7e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 AFI83909.1 - 6.5e-188 624.0 0.1 9.4e-188 623.5 0.1 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 AFI83909.1 - 2.2e-93 311.3 0.0 5.7e-93 310.0 0.0 1.7 2 0 0 2 2 2 1 XFP C-terminal domain XFP PF03894.15 AFI83909.1 - 1e-89 298.9 0.0 1.5e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 AFI83909.1 - 0.0065 16.3 0.1 0.02 14.7 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain THF_DHG_CYH_C PF02882.19 AFI83910.1 - 5e-69 230.7 0.4 7.9e-69 230.1 0.4 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AFI83910.1 - 3.3e-40 137.0 0.1 4.9e-40 136.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Proton_antipo_M PF00361.20 AFI83911.1 - 3.7e-30 105.1 27.1 3.7e-30 105.1 27.1 2.6 2 1 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_M PF00361.20 AFI83912.1 - 1.2e-60 205.2 18.4 1.9e-60 204.5 18.4 1.3 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AFI83912.1 - 0.00019 21.5 1.5 0.00051 20.1 0.1 2.5 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 AFI83913.1 - 1.4e-45 155.7 27.5 1.4e-45 155.7 27.5 2.4 3 0 0 3 3 3 1 Proton-conducting membrane transporter Oxidored_q2 PF00420.24 AFI83914.1 - 5.8e-12 45.2 2.6 7.2e-12 44.9 2.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PhaG_MnhG_YufB PF03334.14 AFI83914.1 - 0.015 15.5 4.4 0.023 14.9 4.4 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter subunit DUF2107 PF09880.9 AFI83914.1 - 0.042 14.0 3.1 0.094 12.8 3.0 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2107) DUF4418 PF14387.6 AFI83914.1 - 0.78 10.0 6.3 4.7 7.4 5.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) MnhB PF04039.13 AFI83915.1 - 7e-16 58.7 7.4 7e-16 58.7 7.4 3.3 2 1 1 3 3 3 2 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 AFI83915.1 - 3.8e-14 52.6 9.5 3.8e-14 52.6 9.5 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4040) Sec20 PF03908.13 AFI83915.1 - 0.3 11.0 1.3 10 6.1 0.0 3.1 3 0 0 3 3 3 0 Sec20 PhaG_MnhG_YufB PF03334.14 AFI83916.1 - 6.2e-22 77.6 5.7 7.8e-22 77.3 5.7 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit DUF2207 PF09972.9 AFI83916.1 - 0.46 9.2 0.8 0.53 9.0 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MrpF_PhaF PF04066.13 AFI83917.1 - 1.9e-10 41.0 6.2 1.9e-10 41.0 6.2 1.9 2 0 0 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) GDP_Man_Dehyd PF16363.5 AFI83919.1 - 6.7e-101 338.0 0.0 7.6e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AFI83919.1 - 2.7e-69 233.3 0.0 3.3e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AFI83919.1 - 1.5e-14 53.7 0.0 3.4e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AFI83919.1 - 1.3e-13 50.7 0.0 2.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AFI83919.1 - 1.5e-13 50.5 0.0 2.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AFI83919.1 - 6.8e-11 41.8 0.1 2.3e-06 27.0 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AFI83919.1 - 9.6e-06 25.2 0.0 0.027 13.9 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 AFI83919.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Gp_dh_N PF00044.24 AFI83919.1 - 0.033 14.5 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AFI83919.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding NTP_transferase PF00483.23 AFI83920.1 - 7.5e-72 241.9 0.0 9.9e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI83920.1 - 1.1e-11 45.4 0.0 1.4e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AFI83920.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.26 AFI83920.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 M60-like_N PF17291.2 AFI83920.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases dTDP_sugar_isom PF00908.17 AFI83921.1 - 4.9e-72 241.1 0.0 6e-72 240.8 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase RmlD_sub_bind PF04321.17 AFI83922.1 - 3e-108 361.3 0.1 3.4e-108 361.1 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AFI83922.1 - 1.1e-17 64.3 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI83922.1 - 1.1e-10 41.5 0.4 2e-10 40.6 0.1 1.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AFI83922.1 - 2.3e-05 23.7 0.4 8.6e-05 21.8 0.4 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AFI83922.1 - 0.00058 19.1 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein PSII_Pbs31 PF18240.1 AFI83922.1 - 0.0081 16.6 0.8 0.029 14.8 0.1 1.9 2 0 0 2 2 2 1 Photosystem II Psb31 protein Polysacc_synt_2 PF02719.15 AFI83923.1 - 1.6e-122 408.3 1.6 2e-122 408.0 1.6 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AFI83923.1 - 2.9e-16 59.7 0.1 2.2e-15 56.8 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI83923.1 - 5.6e-09 35.8 0.0 2.9e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase CoA_binding_3 PF13727.6 AFI83923.1 - 3.5e-08 33.6 0.1 3.5e-08 33.6 0.1 2.4 1 1 1 2 2 2 1 CoA-binding domain RmlD_sub_bind PF04321.17 AFI83923.1 - 4.5e-08 32.5 0.6 2.5e-06 26.8 0.6 2.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AFI83923.1 - 3.6e-07 29.5 0.1 5.6e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AFI83923.1 - 0.0006 19.3 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 AFI83923.1 - 0.00075 18.7 3.2 0.48 9.5 0.0 3.0 2 1 1 3 3 3 2 Male sterility protein KR PF08659.10 AFI83923.1 - 0.0067 16.4 0.6 0.014 15.3 0.2 1.7 2 0 0 2 2 2 1 KR domain DapB_N PF01113.20 AFI83923.1 - 0.09 12.9 0.0 15 5.8 0.0 2.9 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus PglD_N PF17836.1 AFI83923.1 - 0.15 12.7 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 AFI83924.1 - 2.8e-32 111.8 0.1 4.8e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AFI83924.1 - 6.2e-27 93.6 0.0 1.7e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AFI83924.1 - 5.4e-09 36.4 1.6 8.2e-07 29.4 0.1 2.6 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 AFI83924.1 - 1e-05 25.3 0.1 1.7e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 AFI83924.1 - 1.7e-05 24.8 0.2 3.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AFI83924.1 - 0.00021 21.8 0.6 0.0024 18.4 0.1 2.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AFI83924.1 - 0.00023 21.1 1.3 0.0022 17.9 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 AFI83924.1 - 0.00025 21.3 0.9 0.0074 16.5 0.5 3.0 2 1 0 2 2 1 1 TrkA-N domain NAD_binding_2 PF03446.15 AFI83924.1 - 0.00069 19.8 0.3 0.0066 16.6 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 AFI83924.1 - 0.00074 20.0 0.1 0.002 18.6 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 AFI83924.1 - 0.0014 18.7 0.1 0.003 17.6 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Methyltransf_16 PF10294.9 AFI83924.1 - 0.0033 17.2 0.1 0.0079 15.9 0.1 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Glyco_hydro_4 PF02056.16 AFI83924.1 - 0.0071 15.9 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase DapB_N PF01113.20 AFI83924.1 - 0.027 14.6 0.1 0.08 13.1 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Rol_Rep_N PF18106.1 AFI83924.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain Pyr_redox PF00070.27 AFI83924.1 - 0.042 14.4 0.0 0.62 10.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF11 PF01345.18 AFI83924.1 - 0.062 13.6 0.1 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF11 DAO PF01266.24 AFI83924.1 - 0.73 9.3 2.1 0.97 8.9 1.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase SIS PF01380.22 AFI83925.1 - 1.9e-56 189.5 1.2 5.1e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AFI83925.1 - 5.6e-19 68.7 0.2 1.3e-18 67.4 0.1 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AFI83925.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AFI83925.1 - 0.00073 18.5 0.1 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 AFI83925.1 - 0.12 11.0 0.1 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II HTH_24 PF13412.6 AFI83926.1 - 1.1e-14 53.7 0.3 1.1e-14 53.7 0.3 1.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AFI83926.1 - 2.9e-05 23.9 0.1 4.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AFI83926.1 - 0.00045 20.7 0.0 0.00094 19.6 0.0 1.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_AsnC-type PF13404.6 AFI83926.1 - 0.0005 19.8 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain DUF4423 PF14394.6 AFI83926.1 - 0.0011 18.7 2.3 0.061 13.0 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4423) HTH_20 PF12840.7 AFI83926.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Replic_Relax PF13814.6 AFI83926.1 - 0.004 17.2 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation MarR_2 PF12802.7 AFI83926.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.6 AFI83926.1 - 0.017 15.3 0.6 0.022 14.9 0.2 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_5 PF01022.20 AFI83926.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TFIIE_alpha PF02002.17 AFI83926.1 - 0.023 14.5 0.7 0.046 13.6 0.7 1.6 1 1 0 1 1 1 0 TFIIE alpha subunit DUF1712 PF08217.11 AFI83926.1 - 0.023 13.2 0.4 0.025 13.1 0.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) HTH_23 PF13384.6 AFI83926.1 - 0.024 14.4 0.3 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain RepL PF05732.11 AFI83926.1 - 0.035 13.5 0.8 0.083 12.3 0.8 1.6 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_Crp_2 PF13545.6 AFI83926.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain FeoC PF09012.10 AFI83926.1 - 0.056 13.5 0.2 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_11 PF08279.12 AFI83926.1 - 0.061 13.3 0.1 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 HTH domain HrpB7 PF09486.10 AFI83926.1 - 0.063 13.7 0.5 0.079 13.3 0.5 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HTH_IclR PF09339.10 AFI83926.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 AFI83926.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Transposase DUF2250 PF10007.9 AFI83926.1 - 0.12 12.5 1.5 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DegT_DnrJ_EryC1 PF01041.17 AFI83927.1 - 2e-105 353.1 0.0 2.5e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AFI83927.1 - 4.8e-05 22.1 0.0 7.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AFI83927.1 - 0.0002 20.7 0.2 0.0013 18.1 0.2 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AFI83927.1 - 0.0007 18.9 0.1 0.0017 17.6 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AFI83927.1 - 0.002 17.1 0.2 0.0049 15.9 0.2 1.6 1 1 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 AFI83927.1 - 0.026 13.1 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase WbqC PF08889.11 AFI83928.1 - 1.3e-68 231.1 0.1 1.6e-68 230.9 0.1 1.0 1 0 0 1 1 1 1 WbqC-like protein family Epimerase PF01370.21 AFI83929.1 - 1.1e-28 100.4 0.2 1.4e-28 100.0 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI83929.1 - 1.4e-17 64.1 0.3 2.7e-17 63.2 0.3 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AFI83929.1 - 5.4e-14 51.8 1.1 1e-13 51.0 1.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AFI83929.1 - 6.9e-11 41.8 0.3 6.2e-09 35.4 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 AFI83929.1 - 4.7e-06 25.9 0.4 0.002 17.3 0.3 3.4 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AFI83929.1 - 6e-05 23.0 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AFI83929.1 - 0.063 13.2 0.4 5.8 6.8 0.4 2.6 1 1 0 1 1 1 0 KR domain DXP_reductoisom PF02670.16 AFI83929.1 - 0.097 13.4 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DASH_Spc19 PF08287.11 AFI83929.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Spc19 Sulfotransfer_1 PF00685.27 AFI83930.1 - 0.002 17.7 2.4 0.0087 15.6 2.4 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AFI83930.1 - 0.084 13.2 0.1 0.58 10.5 0.1 2.1 1 1 0 1 1 1 0 Sulfotransferase family PA28_alpha PF02251.18 AFI83930.1 - 0.13 12.3 4.3 1.1 9.4 0.2 3.5 4 0 0 4 4 4 0 Proteasome activator pa28 alpha subunit Sulfotransfer_4 PF17784.1 AFI83931.1 - 8.3e-24 84.6 0.7 8.7e-23 81.3 0.7 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AFI83931.1 - 7.8e-07 29.7 0.2 0.00043 20.7 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family MTS_N PF08468.11 AFI83931.1 - 0.054 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Polysacc_synt_3 PF13440.6 AFI83932.1 - 4.9e-78 262.3 22.1 4.9e-78 262.3 22.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AFI83932.1 - 2.6e-30 105.7 23.8 2.6e-30 105.7 23.8 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AFI83932.1 - 1.4e-10 41.4 10.6 1.4e-10 41.4 10.6 4.1 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF2456 PF10445.9 AFI83932.1 - 0.8 9.8 13.7 0.5 10.5 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2456) Glycos_transf_2 PF00535.26 AFI83933.1 - 2.2e-16 60.1 0.6 3.6e-16 59.4 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AFI83933.1 - 6.6e-07 29.4 0.0 9.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AFI83933.1 - 0.015 15.8 0.1 0.033 14.7 0.1 1.7 1 1 1 2 2 2 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 AFI83934.1 - 7.2e-27 94.3 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AFI83934.1 - 6.5e-14 52.4 0.0 1.2e-13 51.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AFI83934.1 - 5.7e-13 49.0 0.3 8.8e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AFI83934.1 - 0.0049 16.8 0.1 0.015 15.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 FBPase_3 PF01950.16 AFI83934.1 - 0.056 12.6 0.0 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase Glyco_tranf_2_3 PF13641.6 AFI83935.1 - 1.5e-09 38.1 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 AFI83935.1 - 1.5e-08 34.2 0.0 2.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 AFI83935.1 - 8.1e-06 25.8 0.1 2.3e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AFI83935.1 - 1.3e-05 24.9 0.1 1.7e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AFI83935.1 - 1.6e-05 24.5 0.0 3.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AFI83935.1 - 2.1e-05 24.5 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 PGM_PMM_I PF02878.16 AFI83936.1 - 1e-34 119.2 0.0 3.8e-34 117.4 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AFI83936.1 - 4.9e-25 87.9 0.0 8.4e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AFI83936.1 - 1.8e-21 76.6 0.1 3.8e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AFI83936.1 - 6.6e-10 39.0 0.1 1.6e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AtuA PF07287.11 AFI83936.1 - 0.052 12.3 0.0 0.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Acyclic terpene utilisation family protein AtuA DUF2218 PF09981.9 AFI83936.1 - 0.18 12.2 0.0 0.53 10.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) Epimerase PF01370.21 AFI83937.1 - 2.4e-36 125.4 0.0 3.1e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AFI83937.1 - 7.6e-24 84.3 0.1 2.1e-16 59.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 AFI83937.1 - 8.7e-24 84.0 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AFI83937.1 - 3.3e-22 79.3 0.0 1.6e-21 77.1 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AFI83937.1 - 9.7e-21 74.1 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AFI83937.1 - 1.8e-20 73.6 0.0 2.4e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AFI83937.1 - 6.3e-11 41.9 1.8 1.9e-09 37.1 1.8 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 AFI83937.1 - 4.9e-10 39.4 1.1 8.2e-10 38.6 1.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AFI83937.1 - 0.00032 20.2 1.1 0.00062 19.3 1.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DDE_Tnp_1_3 PF13612.6 AFI83937.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DapB_N PF01113.20 AFI83937.1 - 0.016 15.4 0.1 0.032 14.4 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 AFI83937.1 - 0.023 14.6 1.0 0.095 12.6 0.9 2.0 2 1 0 2 2 2 0 KR domain F420_oxidored PF03807.17 AFI83937.1 - 0.028 15.0 0.1 0.092 13.3 0.1 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Bac_transf PF02397.16 AFI83938.1 - 8.7e-51 172.1 0.1 1e-50 171.9 0.1 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase NTP_transferase PF00483.23 AFI83939.1 - 5.7e-43 147.3 0.0 6.8e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 AFI83939.1 - 6.9e-13 48.7 0.1 3.2e-12 46.6 0.2 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase SBP_bac_8 PF13416.6 AFI83940.1 - 0.0012 18.8 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Capsule_synth PF05159.14 AFI83940.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein GP38 PF05268.11 AFI83940.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 bZIP_1 PF00170.21 AFI83940.1 - 0.18 11.9 2.5 0.18 11.9 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor HMGL-like PF00682.19 AFI83941.1 - 4.3e-17 62.6 0.0 6.1e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Csd3_N PF18059.1 AFI83941.1 - 0.12 12.9 1.6 0.69 10.5 0.1 2.4 2 1 0 2 2 2 0 Csd3 N-terminal CTP_transf_3 PF02348.19 AFI83942.1 - 4.1e-44 151.1 0.5 5.1e-44 150.8 0.5 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AFI83942.1 - 3.5e-05 24.2 0.0 4.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AFI83942.1 - 0.00067 19.5 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_3 PF00591.21 AFI83942.1 - 0.00072 19.2 0.0 0.00096 18.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Sacchrp_dh_NADP PF03435.18 AFI83942.1 - 0.074 13.3 2.3 5.5 7.3 0.2 2.8 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Mitoc_L55 PF09776.9 AFI83942.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 TMEM240 PF15207.6 AFI83942.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM240 family HAD_2 PF13419.6 AFI83943.1 - 4.8e-18 65.9 0.3 8.1e-18 65.1 0.3 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 AFI83943.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 AFI83943.1 - 0.012 16.1 0.0 0.042 14.2 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CAS_C PF12026.8 AFI83943.1 - 0.029 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Hydrolase_like PF13242.6 AFI83943.1 - 0.083 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Glycos_transf_1 PF00534.20 AFI83944.1 - 7.1e-13 48.4 0.0 1.5e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI83944.1 - 1.3e-07 32.2 0.0 2.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI83944.1 - 0.00026 21.3 0.0 0.0015 18.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Methyltransf_21 PF05050.12 AFI83945.1 - 3.5e-14 53.2 0.1 4.7e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain GDP_Man_Dehyd PF16363.5 AFI83946.1 - 6.3e-137 456.4 0.0 7.1e-137 456.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AFI83946.1 - 4.9e-67 225.9 0.0 6.2e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AFI83946.1 - 4.1e-07 29.4 0.0 6.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AFI83946.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 AFI83946.1 - 0.04 13.8 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AFI83947.1 - 1.1e-39 136.8 1.0 4.6e-35 121.6 0.0 2.5 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AFI83947.1 - 6.6e-39 133.8 0.1 8.8e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AFI83947.1 - 1.5e-14 53.8 0.1 1.8e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AFI83947.1 - 5.7e-11 42.1 2.6 3.5e-10 39.5 0.4 2.8 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 AFI83947.1 - 8.6e-10 38.1 1.2 8.5e-08 31.5 0.2 2.3 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AFI83947.1 - 6.5e-06 26.2 0.2 2.7e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AFI83947.1 - 0.00019 20.7 1.9 0.00036 19.8 0.6 2.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 AFI83947.1 - 0.014 15.0 0.3 0.5 9.9 0.0 2.4 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_1 PF00534.20 AFI83948.1 - 5.3e-29 100.9 0.0 8.4e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI83948.1 - 1.2e-20 74.3 0.0 2.5e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI83948.1 - 8.5e-08 32.5 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI83948.1 - 4.3e-07 30.1 0.2 1.1e-06 28.8 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI83948.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain HPD PF05044.12 AFI83948.1 - 0.048 13.5 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Homeo-prospero domain Glycos_transf_1 PF00534.20 AFI83949.1 - 1.6e-27 96.1 0.0 2.4e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI83949.1 - 2.8e-20 73.1 0.0 4.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI83949.1 - 3.6e-12 46.6 0.5 6.7e-12 45.7 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI83949.1 - 3.1e-07 31.0 0.0 4.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AFI83949.1 - 8.3e-07 29.3 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AFI83949.1 - 0.006 16.6 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like ABC_tran PF00005.27 AFI83950.1 - 3.5e-20 72.9 0.0 8e-20 71.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI83950.1 - 1.8e-05 24.7 4.9 0.0022 17.9 1.8 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AFI83950.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI83950.1 - 0.0014 18.3 0.2 0.0029 17.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AFI83950.1 - 0.0042 17.6 1.3 0.0066 17.0 1.1 1.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFI83950.1 - 0.0077 16.1 0.1 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AFI83950.1 - 0.015 15.7 0.0 0.018 15.5 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AFI83950.1 - 0.089 12.9 1.0 0.15 12.2 0.3 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 AFI83950.1 - 0.1 12.3 0.8 0.14 11.8 0.7 1.3 1 1 0 1 1 1 0 AAA ATPase domain YajC PF02699.15 AFI83950.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit AAA_13 PF13166.6 AFI83950.1 - 0.17 10.5 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AFI83950.1 - 0.19 11.1 0.7 1 8.7 0.1 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 AFI83950.1 - 0.31 10.9 1.4 5 7.0 0.2 2.2 2 0 0 2 2 2 0 NTPase ABC2_membrane PF01061.24 AFI83951.1 - 7.8e-19 67.9 26.7 1.1e-18 67.5 26.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter TPR_16 PF13432.6 AFI83951.1 - 4.4e-18 65.6 8.9 3.7e-08 33.9 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 AFI83951.1 - 6.3e-13 49.0 5.9 1.4e-05 25.5 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 AFI83951.1 - 4.2e-09 36.5 1.9 0.038 14.8 0.1 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI83951.1 - 0.00011 22.3 0.2 0.023 14.9 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 AFI83951.1 - 0.00088 19.2 4.3 6.6 7.1 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.9 AFI83951.1 - 0.0035 16.2 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 AFI83951.1 - 0.0097 16.5 3.2 2 9.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 AFI83951.1 - 0.02 15.2 8.0 3.5 8.0 0.2 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AFI83951.1 - 0.054 13.6 1.6 8 6.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 AFI83951.1 - 0.13 12.7 0.7 61 4.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI83951.1 - 0.18 11.7 0.5 41 4.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat APS_kinase PF01583.20 AFI83953.1 - 6.7e-75 250.3 0.0 8.2e-75 250.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AFI83953.1 - 5.6e-07 29.8 0.0 7.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AFI83953.1 - 0.002 18.6 0.0 0.0038 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AFI83953.1 - 0.0056 16.2 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 AFI83953.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI83953.1 - 0.04 14.3 0.0 0.054 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 AFI83953.1 - 0.06 13.4 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DHHA1 PF02272.19 AFI83954.1 - 2.7e-05 24.6 0.0 6.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 AFI83954.1 - 0.00067 19.9 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 DHH family HHH_3 PF12836.7 AFI83955.1 - 2.2e-24 85.5 0.4 2.8e-24 85.1 0.4 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AFI83955.1 - 4e-15 54.8 0.1 1.1e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 AFI83955.1 - 4.2e-07 30.5 1.3 0.00012 22.6 0.4 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 AFI83955.1 - 1.5e-06 28.2 0.3 0.0022 18.0 0.0 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_6 PF14579.6 AFI83955.1 - 9.8e-06 25.7 0.1 6.4e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 AFI83955.1 - 3.5e-05 23.3 0.2 5.2e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K PsbU PF06514.11 AFI83955.1 - 5.8e-05 23.0 0.0 7.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_8 PF14716.6 AFI83955.1 - 6.6e-05 23.2 0.4 0.17 12.3 0.0 2.1 1 1 1 2 2 2 2 Helix-hairpin-helix domain Ribosomal_S13 PF00416.22 AFI83955.1 - 0.054 13.9 0.3 12 6.3 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein S13/S18 DUF655 PF04919.12 AFI83955.1 - 0.068 13.1 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) HRDC PF00570.23 AFI83955.1 - 0.096 12.7 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 HRDC domain LAGLIDADG_1 PF00961.19 AFI83956.1 - 1.2e-07 32.7 0.0 1.7e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_3 PF14528.6 AFI83956.1 - 0.0046 17.3 0.0 0.0069 16.7 0.0 1.3 1 0 0 1 1 1 1 LAGLIDADG-like domain Endonuc_subdom PF09062.10 AFI83956.1 - 0.0082 16.9 0.0 0.011 16.5 0.0 1.3 1 0 0 1 1 1 1 PI-PfuI Endonuclease subdomain Peptidase_M15_3 PF08291.11 AFI83956.1 - 0.012 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase M15 AAA PF00004.29 AFI83957.1 - 2.5e-15 57.1 0.0 1.3e-14 54.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI83957.1 - 1.6e-05 25.3 0.3 0.0042 17.5 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 AFI83957.1 - 2.1e-05 24.6 0.0 7.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AFI83957.1 - 0.00094 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 AFI83957.1 - 0.0036 17.8 0.0 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 AFI83957.1 - 0.0089 15.9 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AFI83957.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AFI83957.1 - 0.013 15.8 0.1 0.5 10.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AFI83957.1 - 0.035 13.9 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AFI83957.1 - 0.043 14.2 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 AFI83957.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AFI83957.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 AFI83957.1 - 0.074 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 AFI83957.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AFI83957.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 AFI83957.1 - 0.15 11.5 0.1 0.83 9.0 0.0 2.0 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AFI83957.1 - 0.15 12.0 0.1 2.5 8.0 0.0 2.5 2 1 1 3 3 3 0 NACHT domain DDE_Tnp_IS66 PF03050.14 AFI83959.1 - 5.1e-103 344.4 0.0 9.8e-103 343.5 0.0 1.5 1 0 0 1 1 1 1 Transposase IS66 family LZ_Tnp_IS66 PF13007.7 AFI83959.1 - 3.7e-16 59.6 4.4 7.9e-16 58.6 4.4 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain zf-IS66 PF13005.7 AFI83959.1 - 5.9e-16 58.6 2.2 1.2e-15 57.6 2.2 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 DDE_Tnp_IS66_C PF13817.6 AFI83959.1 - 9.9e-15 54.5 0.0 2.2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 IS66 C-terminal element DZR PF12773.7 AFI83959.1 - 0.074 13.1 1.2 0.13 12.3 1.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Sgf11 PF08209.11 AFI83959.1 - 0.5 10.0 3.1 13 5.5 0.3 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) TnpB_IS66 PF05717.13 AFI83960.1 - 5.1e-43 145.1 0.1 5.7e-43 144.9 0.1 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 AFI83961.1 - 1.1e-14 54.5 0.3 1.5e-14 54.1 0.3 1.2 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AFI83961.1 - 1.2e-08 35.0 0.4 2.1e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI83961.1 - 8.9e-07 28.5 0.3 1.4e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 AFI83961.1 - 5.8e-06 25.8 0.0 8.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 AFI83961.1 - 0.0031 16.9 0.2 0.0081 15.6 0.0 1.8 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 GlnD_UR_UTase PF08335.11 AFI83964.1 - 6.4e-37 126.9 5.8 5.2e-35 120.7 4.5 3.2 2 1 1 3 3 3 1 GlnD PII-uridylyltransferase HD PF01966.22 AFI83964.1 - 3.2e-10 40.3 0.0 1.5e-09 38.1 0.0 2.2 1 0 0 1 1 1 1 HD domain NTP_transf_2 PF01909.23 AFI83964.1 - 6.8e-07 29.5 0.1 8.5e-06 26.0 0.0 2.6 2 1 0 2 2 2 1 Nucleotidyltransferase domain ACT_6 PF13740.6 AFI83964.1 - 4.9e-06 26.4 0.2 0.03 14.3 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 AFI83964.1 - 1.8e-05 25.2 0.7 0.15 12.6 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AFI83964.1 - 0.00042 20.0 0.0 0.0017 18.1 0.0 2.1 1 0 0 1 1 1 1 ACT domain DUF294 PF03445.13 AFI83964.1 - 0.004 17.0 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 Polbeta PF18765.1 AFI83964.1 - 0.0097 16.0 0.0 0.036 14.2 0.0 2.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Peptidase_M24 PF00557.24 AFI83965.1 - 6.6e-54 182.8 0.9 7.5e-54 182.6 0.9 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S2 PF00318.20 AFI83966.1 - 1.8e-94 315.0 0.0 2e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Peripla_BP_1 PF00532.21 AFI83966.1 - 0.0014 18.1 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family PucR PF07905.11 AFI83966.1 - 0.043 14.1 0.0 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family EF_TS PF00889.19 AFI83967.1 - 1.2e-72 243.9 0.7 1.7e-72 243.4 0.7 1.2 1 0 0 1 1 1 1 Elongation factor TS HOIP-UBA PF16678.5 AFI83967.1 - 0.0037 17.3 0.5 0.12 12.4 0.1 2.3 2 1 1 3 3 3 2 HOIP UBA domain pair UBA PF00627.31 AFI83967.1 - 0.039 13.9 0.2 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 UBA/TS-N domain DUF1296 PF06972.11 AFI83967.1 - 0.041 14.0 0.0 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) AA_kinase PF00696.28 AFI83968.1 - 5.2e-30 104.8 0.2 6e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF647 PF04884.14 AFI83968.1 - 0.055 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis RRF PF01765.19 AFI83969.1 - 6.5e-61 205.0 0.9 6.5e-61 205.0 0.9 1.4 2 0 0 2 2 2 1 Ribosome recycling factor TBCA PF02970.16 AFI83969.1 - 0.013 15.8 1.7 0.13 12.6 0.6 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor A Prenyltransf PF01255.19 AFI83970.1 - 1.2e-78 263.7 0.0 1.4e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CTP_transf_1 PF01148.20 AFI83971.1 - 7.6e-59 199.6 26.2 8.5e-59 199.5 26.2 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family DXP_reductoisom PF02670.16 AFI83972.1 - 2.9e-44 150.9 1.3 5.3e-44 150.1 1.3 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 AFI83972.1 - 6.1e-43 145.8 0.1 1.2e-42 144.8 0.1 1.5 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AFI83972.1 - 2.6e-41 139.7 0.0 6.4e-41 138.4 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 AFI83972.1 - 0.007 16.8 0.2 0.033 14.6 0.2 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AFI83972.1 - 0.027 15.1 0.4 0.25 12.0 0.4 2.4 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.13 AFI83972.1 - 0.13 11.8 0.3 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family Peptidase_M50 PF02163.22 AFI83973.1 - 1.1e-82 277.0 0.3 1.3e-82 276.8 0.3 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AFI83973.1 - 5e-21 74.3 0.1 3e-12 46.2 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 AFI83973.1 - 8.3e-18 64.5 0.0 7.1e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AFI83973.1 - 3.5e-12 46.5 0.0 9.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.14 AFI83973.1 - 6.9e-05 23.2 0.0 0.53 10.6 0.0 2.5 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 AFI83973.1 - 0.00059 19.8 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain DUF3394 PF11874.8 AFI83973.1 - 0.0052 16.5 1.1 0.044 13.5 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3394) Bac_surface_Ag PF01103.23 AFI83974.1 - 5.1e-79 266.1 15.3 5.1e-79 266.1 15.3 2.3 2 1 1 3 3 3 1 Surface antigen POTRA PF07244.15 AFI83974.1 - 3e-64 213.6 20.6 9.7e-18 64.5 0.2 6.0 6 0 0 6 6 6 5 Surface antigen variable number repeat POTRA_2 PF08479.11 AFI83974.1 - 8.3e-10 38.4 0.5 0.0071 16.2 0.0 5.5 5 1 0 5 5 5 2 POTRA domain, ShlB-type POTRA_1 PF08478.10 AFI83974.1 - 6.8e-09 35.9 2.7 0.22 11.8 0.1 5.2 5 0 0 5 5 5 3 POTRA domain, FtsQ-type YqfD PF06898.11 AFI83974.1 - 0.008 15.0 0.4 0.46 9.3 0.0 3.0 3 0 0 3 3 3 1 Putative stage IV sporulation protein YqfD DUF1410 PF07198.11 AFI83974.1 - 0.12 12.8 0.1 0.36 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) UvrB_inter PF17757.1 AFI83974.1 - 0.14 12.3 0.4 2 8.7 0.1 3.0 2 1 0 2 2 2 0 UvrB interaction domain OmpH PF03938.14 AFI83975.1 - 2.2e-25 89.6 11.8 2.5e-25 89.4 11.8 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Synaptonemal_3 PF15191.6 AFI83975.1 - 0.02 14.7 2.6 4.7 7.0 0.1 2.9 1 1 0 2 2 2 0 Synaptonemal complex central element protein 3 Exonuc_VII_L PF02601.15 AFI83975.1 - 0.045 13.3 6.0 0.051 13.1 6.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 AFI83975.1 - 0.048 13.4 3.2 0.063 13.0 2.3 1.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Usp PF00582.26 AFI83975.1 - 0.052 14.1 5.5 0.11 13.0 5.5 1.5 1 1 0 1 1 1 0 Universal stress protein family TMPIT PF07851.13 AFI83975.1 - 2 7.6 5.7 2.5 7.3 5.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Hexapep PF00132.24 AFI83976.1 - 1.9e-26 90.7 38.8 6.8e-07 28.8 4.0 6.5 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 AFI83976.1 - 1.5e-22 79.2 0.2 2.3e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 AFI83976.1 - 6.4e-10 38.6 33.0 0.011 15.4 1.4 6.6 6 0 0 6 6 6 5 Hexapeptide repeat of succinyl-transferase zf-RING_6 PF14835.6 AFI83976.1 - 0.16 11.8 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FabA PF07977.13 AFI83977.1 - 2.2e-37 127.7 0.0 2.6e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 AFI83977.1 - 0.0039 16.7 0.0 0.0076 15.8 0.0 1.5 1 1 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 AFI83977.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 Thioesterase superfamily DUF2808 PF10989.8 AFI83977.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Acetyltransf_11 PF13720.6 AFI83978.1 - 1.5e-25 89.5 0.1 2.2e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AFI83978.1 - 7.5e-22 76.2 18.5 1.6e-09 37.1 1.1 5.7 4 2 2 6 6 6 5 Bacterial transferase hexapeptide (six repeats) MerR_1 PF13411.6 AFI83978.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Hexapep_2 PF14602.6 AFI83978.1 - 4.7 7.1 12.1 0.43 10.4 1.4 3.9 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase Ammonium_transp PF00909.21 AFI83979.1 - 1.1e-89 300.9 27.6 1.3e-89 300.7 27.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TPR_21 PF09976.9 AFI83980.1 - 9.3e-52 175.5 11.8 1.1e-51 175.3 11.8 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 AFI83980.1 - 0.0032 17.4 1.2 2.7 8.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.6 AFI83980.1 - 0.0049 16.6 5.0 0.0049 16.6 5.0 2.0 2 1 0 2 2 2 1 Outer membrane lipoprotein ANAPC3 PF12895.7 AFI83980.1 - 0.0057 16.9 5.7 0.015 15.5 1.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 AFI83980.1 - 0.0071 16.1 8.0 0.72 9.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 AFI83980.1 - 0.012 15.6 8.6 0.44 10.8 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 AFI83980.1 - 0.016 16.0 11.6 0.26 12.2 0.1 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 AFI83980.1 - 0.022 15.3 16.9 0.03 14.8 4.9 3.0 2 1 0 3 3 3 0 Tetratricopeptide repeat ESX-1_EspG PF14011.6 AFI83980.1 - 0.028 14.0 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 EspG family TPR_16 PF13432.6 AFI83980.1 - 0.033 14.8 11.4 0.096 13.3 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AFI83980.1 - 0.036 14.3 6.2 6.9 7.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 AFI83980.1 - 0.038 14.0 0.4 0.27 11.3 0.0 2.0 1 1 1 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.6 AFI83980.1 - 0.051 13.9 9.4 0.55 10.6 5.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat T6SS_VasJ PF16989.5 AFI83980.1 - 0.076 12.5 9.2 0.33 10.4 9.2 1.8 1 1 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_18 PF13512.6 AFI83980.1 - 0.082 13.0 8.0 0.04 14.0 2.7 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AFI83980.1 - 0.091 13.1 12.0 0.88 9.9 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 AFI83980.1 - 0.14 11.9 10.8 0.22 11.3 0.4 3.6 4 0 0 4 4 4 0 TPR repeat TPR_MalT PF17874.1 AFI83980.1 - 0.29 10.5 13.7 0.89 8.9 6.2 2.8 1 1 1 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 AFI83980.1 - 0.55 11.0 15.6 1.3 9.8 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 AFI83980.1 - 0.83 9.6 0.0 0.83 9.6 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AFI83980.1 - 2 9.3 5.5 2.4 9.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PQQ_2 PF13360.6 AFI83981.1 - 2.4e-59 200.8 15.8 4.8e-53 180.2 8.5 2.6 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AFI83981.1 - 1.2e-29 101.9 20.5 2.3e-05 24.7 0.1 8.4 8 1 0 8 8 8 7 PQQ-like domain PQQ PF01011.21 AFI83981.1 - 7.4e-24 82.5 5.6 6.7e-06 25.8 0.0 6.4 7 0 0 7 7 7 4 PQQ enzyme repeat Tachylectin PF14517.6 AFI83981.1 - 0.074 12.6 0.8 17 4.9 0.1 3.1 3 0 0 3 3 3 0 Tachylectin MMR_HSR1 PF01926.23 AFI83982.1 - 1e-51 173.8 0.7 2.9e-26 91.8 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI83982.1 - 1.1e-31 109.5 0.2 8.9e-15 54.6 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 AFI83982.1 - 2.2e-27 95.2 0.2 4.1e-27 94.3 0.2 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 AFI83982.1 - 2.6e-19 69.5 1.1 7.4e-09 35.4 0.0 5.1 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AFI83982.1 - 2.4e-12 47.3 0.7 0.0056 16.7 0.0 4.2 2 2 2 4 4 4 4 Dynamin family RsgA_GTPase PF03193.16 AFI83982.1 - 7.5e-10 39.0 0.1 0.0026 17.7 0.0 4.4 3 1 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 AFI83982.1 - 2.6e-08 33.5 0.1 0.00028 20.3 0.0 2.4 2 0 0 2 2 2 2 AIG1 family AAA_22 PF13401.6 AFI83982.1 - 1e-06 29.1 0.0 0.046 14.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 AFI83982.1 - 2.1e-06 27.9 0.0 0.032 14.5 0.0 2.9 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 AFI83982.1 - 4.2e-06 26.5 2.2 0.088 12.4 0.1 3.4 2 1 2 4 4 4 2 SRP54-type protein, GTPase domain SRPRB PF09439.10 AFI83982.1 - 5.9e-05 22.6 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 AFI83982.1 - 0.00011 21.9 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 AFI83982.1 - 0.00018 21.9 0.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Spore_IV_A PF09547.10 AFI83982.1 - 0.00018 20.6 0.0 0.089 11.7 0.0 2.4 2 0 0 2 2 2 2 Stage IV sporulation protein A (spore_IV_A) TniB PF05621.11 AFI83982.1 - 0.00018 21.0 0.0 0.36 10.2 0.0 2.9 3 0 0 3 3 3 2 Bacterial TniB protein Ras PF00071.22 AFI83982.1 - 0.00026 20.6 0.0 0.56 9.8 0.0 2.5 2 0 0 2 2 2 2 Ras family cobW PF02492.19 AFI83982.1 - 0.00026 20.6 6.9 2.1 7.9 0.2 4.2 2 2 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 AFI83982.1 - 0.00036 20.4 0.0 0.24 11.2 0.0 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AFI83982.1 - 0.00038 21.0 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 AFI83982.1 - 0.00042 20.5 0.0 1.9 8.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain PduV-EutP PF10662.9 AFI83982.1 - 0.00059 19.6 0.0 0.038 13.7 0.0 3.1 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 AFI83982.1 - 0.001 19.1 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AFI83982.1 - 0.0015 19.0 0.1 0.71 10.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 AFI83982.1 - 0.0021 17.1 1.3 4.4 6.2 0.0 3.9 3 2 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 AFI83982.1 - 0.0023 18.5 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AFI83982.1 - 0.0023 17.8 0.2 4.1 7.3 0.0 3.1 3 1 0 3 3 3 1 NTPase NB-ARC PF00931.22 AFI83982.1 - 0.004 16.4 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Septin PF00735.18 AFI83982.1 - 0.0048 16.2 0.0 0.81 8.9 0.0 2.7 2 1 0 2 2 2 1 Septin Ploopntkinase3 PF18751.1 AFI83982.1 - 0.0069 16.3 0.0 0.41 10.5 0.0 2.6 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 AFI83982.1 - 0.01 16.1 0.0 4.7 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain Nuc_deoxyri_tr2 PF15891.5 AFI83982.1 - 0.014 15.7 0.4 0.78 10.1 0.1 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like AAA_29 PF13555.6 AFI83982.1 - 0.018 14.7 0.0 6 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.14 AFI83982.1 - 0.039 13.9 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TPP_enzyme_N PF02776.18 AFI83982.1 - 0.05 13.2 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AAA_25 PF13481.6 AFI83982.1 - 0.074 12.6 1.4 25 4.4 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 AFI83982.1 - 0.11 12.9 0.0 16 5.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AFI83984.1 - 4.6e-32 111.4 0.0 4.1e-31 108.3 0.0 2.4 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 AFI83984.1 - 1e-23 84.4 12.7 1.5e-23 83.9 12.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AFI83984.1 - 8.7e-06 25.6 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C39 family SMC_N PF02463.19 AFI83984.1 - 0.00055 19.4 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AFI83984.1 - 0.0062 16.4 0.3 0.12 12.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AFI83984.1 - 0.052 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AFI83984.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HlyD_3 PF13437.6 AFI83985.1 - 6.9e-20 71.7 0.1 1.2e-15 58.1 0.0 2.9 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AFI83985.1 - 3.4e-09 36.2 4.9 2.9e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AFI83985.1 - 1.4e-07 31.3 0.2 1.5e-06 27.9 0.1 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.20 AFI83985.1 - 3.2e-06 26.9 0.0 4.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Baculo_PEP_C PF04513.12 AFI83985.1 - 0.0024 17.9 0.1 0.005 16.9 0.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Biotin_lipoyl PF00364.22 AFI83985.1 - 0.025 14.4 3.5 0.079 12.8 0.9 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme TPR_MLP1_2 PF07926.12 AFI83985.1 - 0.044 13.8 0.8 0.044 13.8 0.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 AFI83985.1 - 0.056 13.7 0.3 0.056 13.7 0.3 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein AAA_13 PF13166.6 AFI83985.1 - 0.17 10.5 3.6 0.24 10.0 3.6 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase_C PF13335.6 AFI83985.1 - 0.34 11.6 4.9 0.18 12.5 1.6 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal FlaC_arch PF05377.11 AFI83985.1 - 0.64 10.5 8.3 5.4 7.5 0.8 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) OEP PF02321.18 AFI83985.1 - 1.4 8.7 14.0 0.46 10.3 11.0 1.6 1 1 1 2 2 2 0 Outer membrane efflux protein Spc7 PF08317.11 AFI83985.1 - 1.6 7.5 14.7 4.6 6.0 14.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein GlutR_dimer PF00745.20 AFI83985.1 - 2.4 8.7 8.4 5.9 7.4 1.6 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF1664 PF07889.12 AFI83985.1 - 4.2 7.4 8.9 0.74 9.9 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GerE PF00196.19 AFI83986.1 - 1.3e-17 63.1 0.7 2.4e-17 62.2 0.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI83986.1 - 0.0012 18.5 0.1 0.004 16.8 0.1 2.1 2 1 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AFI83986.1 - 0.0048 16.4 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AFI83986.1 - 0.0054 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_40 PF14493.6 AFI83986.1 - 0.0066 16.9 0.2 0.034 14.6 0.1 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain Response_reg PF00072.24 AFI83986.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Response regulator receiver domain YlaC PF10777.9 AFI83986.1 - 0.086 12.7 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 Inner membrane protein YlaC HTH_10 PF04967.12 AFI83986.1 - 0.092 12.6 0.0 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_28 PF13518.6 AFI83986.1 - 0.1 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain OEP PF02321.18 AFI83987.1 - 5.9e-52 176.2 21.3 3.6e-28 98.7 8.0 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DUF262 PF03235.14 AFI83987.1 - 0.0087 16.3 1.0 0.0087 16.3 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 TetR_C_27 PF17935.1 AFI83987.1 - 0.15 12.1 2.2 0.52 10.4 0.1 2.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain FabA PF07977.13 AFI83988.1 - 1.6e-51 173.6 0.0 1.8e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain ketoacyl-synt PF00109.26 AFI83989.1 - 4.4e-42 144.4 2.9 7.1e-42 143.7 2.9 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AFI83989.1 - 8.1e-31 106.5 1.3 1.1e-29 102.8 0.5 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AFI83989.1 - 0.00094 18.6 4.0 0.032 13.6 1.4 2.3 1 1 1 2 2 2 2 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AFI83989.1 - 0.18 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension SurA_N_2 PF13623.6 AFI83990.1 - 0.083 12.8 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 SurA N-terminal domain Abhydrolase_1 PF00561.20 AFI83991.1 - 1.8e-27 96.6 0.1 3.8e-21 75.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AFI83991.1 - 9.3e-19 68.9 0.0 1.1e-18 68.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AFI83991.1 - 5.2e-12 45.5 0.0 6.7e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 AFI83991.1 - 6e-10 39.2 0.0 1.8e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 AFI83991.1 - 5.1e-08 33.3 0.0 1.7e-07 31.6 0.0 1.8 1 1 2 3 3 3 1 Thioesterase domain DUF676 PF05057.14 AFI83991.1 - 0.00025 20.6 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.14 AFI83991.1 - 0.0011 17.7 0.0 0.013 14.2 0.0 2.0 1 1 0 1 1 1 1 Ndr family PAF-AH_p_II PF03403.13 AFI83991.1 - 0.0012 17.5 0.0 0.047 12.2 0.0 2.2 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 AFI83991.1 - 0.005 16.6 0.0 1.4 8.7 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 AFI83991.1 - 0.0097 15.3 0.0 0.1 11.9 0.0 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 AFI83991.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Palm_thioest PF02089.15 AFI83991.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase UPF0227 PF05728.12 AFI83991.1 - 0.028 14.3 0.1 0.063 13.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydro_lipase PF04083.16 AFI83991.1 - 0.042 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 AFI83991.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Lipase PF00151.19 AFI83991.1 - 0.077 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Lipase Chlorophyllase2 PF12740.7 AFI83991.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1057 PF06342.12 AFI83991.1 - 0.14 11.1 0.0 0.43 9.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 AFI83991.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 AFI83991.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein MazG-like PF12643.7 AFI83992.1 - 3.9e-22 78.3 1.9 5.2e-22 77.9 1.9 1.2 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 AFI83992.1 - 9.2e-06 25.7 1.2 1.4e-05 25.2 0.8 1.6 2 1 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain Formyl_trans_N PF00551.19 AFI83993.1 - 2.2e-33 115.5 0.0 2.8e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AFI83993.1 - 4.8e-11 42.2 0.0 1.7e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AFI83993.1 - 0.0015 19.0 0.0 0.0043 17.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain SmaI PF17411.2 AFI83993.1 - 0.046 12.9 0.0 0.084 12.0 0.0 1.4 1 1 0 1 1 1 0 Type II site-specific deoxyribonuclease adh_short PF00106.25 AFI83994.1 - 3.5e-54 183.3 0.0 5.7e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AFI83994.1 - 4.1e-39 134.5 0.0 5e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AFI83994.1 - 1.3e-12 48.0 0.0 1.9e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AFI83994.1 - 0.0069 15.9 0.1 0.021 14.3 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AFI83994.1 - 0.029 13.5 0.0 0.076 12.1 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TonB_dep_Rec PF00593.24 AFI83995.1 - 5.9e-32 112.2 13.3 2.3e-31 110.2 13.3 1.8 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI83995.1 - 9.7e-20 71.2 3.3 1.4e-19 70.7 1.6 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI83995.1 - 5.6e-05 22.3 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family DUF2946 PF11162.8 AFI83996.1 - 0.0034 18.0 0.5 0.0052 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2946) G6PD_bact PF10786.9 AFI83996.1 - 0.032 13.8 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Peptidase_M20 PF01546.28 AFI83997.1 - 1e-45 156.0 0.2 1.2e-45 155.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AFI83997.1 - 2e-26 92.1 0.0 6.7e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M18 PF02127.15 AFI83997.1 - 0.042 12.6 0.1 0.062 12.1 0.1 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) ArsC PF03960.15 AFI83998.1 - 2.6e-19 69.0 0.0 2.8e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AFI83998.1 - 0.047 13.9 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin THDPS_N_2 PF14805.6 AFI83999.1 - 2.6e-27 94.8 1.0 4.1e-27 94.2 1.0 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep_2 PF14602.6 AFI83999.1 - 4.8e-13 48.6 10.7 5.7e-13 48.4 1.5 3.6 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AFI83999.1 - 2.7e-12 45.9 10.0 7.5e-07 28.6 0.9 3.6 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Aminotran_1_2 PF00155.21 AFI84000.1 - 1.8e-42 145.8 0.0 2.1e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AFI84000.1 - 4.5e-06 25.7 0.0 6.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 AFI84000.1 - 0.0037 15.9 0.0 0.0051 15.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Flexi_CP_N PF08358.10 AFI84000.1 - 0.086 12.8 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 Carlavirus coat EamA PF00892.20 AFI84001.1 - 2.7e-22 79.4 51.0 3.7e-14 53.0 20.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AFI84001.1 - 2.6e-08 33.5 1.9 2.6e-08 33.5 1.9 2.0 1 1 1 2 2 2 1 Triose-phosphate Transporter family US6 PF17616.2 AFI84001.1 - 2.3 8.1 3.2 5 7.0 0.1 2.2 2 0 0 2 2 2 0 Viral unique short region 6 DUF2613 PF11021.8 AFI84001.1 - 2.6 8.2 5.0 0.63 10.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) Glyoxalase PF00903.25 AFI84002.1 - 6.3e-13 49.0 0.0 9.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AFI84002.1 - 1.4e-08 35.4 0.0 1.8e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AFI84002.1 - 6e-05 23.3 0.0 9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 AFI84002.1 - 0.0025 17.7 0.0 0.0044 16.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AFI84002.1 - 0.055 13.6 0.0 0.076 13.1 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain ATP_bind_3 PF01171.20 AFI84004.1 - 9.5e-16 58.1 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 PP-loop family MoeA_N PF03453.17 AFI84005.1 - 2.6e-44 150.7 0.1 4.5e-44 150.0 0.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AFI84005.1 - 1.9e-31 108.6 0.0 3.7e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AFI84005.1 - 8e-20 70.8 0.0 2.1e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) MobB PF03205.14 AFI84006.1 - 2.7e-48 163.2 0.0 4.4e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NTP_transf_3 PF12804.7 AFI84006.1 - 6.9e-32 111.0 0.1 2.4e-31 109.2 0.0 1.9 2 1 0 2 2 2 1 MobA-like NTP transferase domain cobW PF02492.19 AFI84006.1 - 7.8e-05 22.3 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AFI84006.1 - 0.0038 16.2 0.3 0.0087 15.1 0.1 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 AFI84006.1 - 0.0045 17.0 0.0 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Glycos_transf_2 PF00535.26 AFI84006.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 gag-asp_proteas PF13975.6 AFI84007.1 - 4e-26 91.4 0.3 9.5e-26 90.2 0.2 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AFI84007.1 - 3.7e-22 78.8 0.2 6.5e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 AFI84007.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease YjcQ PF09639.10 AFI84007.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 YjcQ protein GCHY-1 PF02649.14 AFI84008.1 - 1.2e-100 336.4 2.5 1.3e-100 336.2 2.5 1.0 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 ISPD_C PF18706.1 AFI84008.1 - 0.021 14.5 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain PTPS PF01242.19 AFI84009.1 - 1.4e-31 109.0 0.3 1.5e-31 108.9 0.3 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase L_protein_N PF15518.6 AFI84009.1 - 0.091 12.6 0.1 1.6 8.7 0.0 2.2 1 1 1 2 2 2 0 L protein N-terminus DXP_synthase_N PF13292.6 AFI84010.1 - 2.6e-122 407.3 0.4 5.5e-122 406.2 0.1 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AFI84010.1 - 1.1e-36 126.1 0.0 2.3e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AFI84010.1 - 9.9e-26 90.1 0.0 2.4e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AFI84010.1 - 8.1e-07 28.9 0.2 8.2e-06 25.7 0.2 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 AFI84010.1 - 9.6e-07 28.1 0.7 7.7e-06 25.1 0.9 2.1 2 1 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 AFI84010.1 - 1.4e-05 24.2 0.2 2.5e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component polyprenyl_synt PF00348.17 AFI84011.1 - 1.5e-56 191.3 4.4 1.7e-56 191.1 4.4 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Exonuc_VII_S PF02609.16 AFI84012.1 - 1.9e-20 72.7 5.4 2.5e-20 72.3 5.4 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit Caskin-tail PF16632.5 AFI84012.1 - 0.021 15.2 0.8 8.3 6.9 0.3 2.3 1 1 1 2 2 2 0 C-terminal region of Caskin Vps53_N PF04100.12 AFI84012.1 - 0.074 12.0 0.8 0.083 11.8 0.8 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal HU-CCDC81_bac_2 PF18175.1 AFI84012.1 - 0.34 10.8 3.3 0.86 9.5 0.2 2.1 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 SHOCT PF09851.9 AFI84012.1 - 2.2 8.1 7.6 0.72 9.7 0.9 3.0 2 1 2 4 4 4 0 Short C-terminal domain FAD_syn PF06574.12 AFI84013.1 - 1.8e-54 183.9 0.1 3e-54 183.2 0.1 1.3 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 AFI84013.1 - 6.1e-41 139.2 0.0 1.4e-40 138.1 0.0 1.6 2 0 0 2 2 2 1 Riboflavin kinase CTP_transf_like PF01467.26 AFI84013.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2007 PF09413.10 AFI84014.1 - 2.1e-13 50.2 0.0 2.4e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Putative prokaryotic signal transducing protein NlpE_C PF17185.4 AFI84015.1 - 3.5e-26 91.3 0.0 7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 NlpE C-terminal OB domain META PF03724.16 AFI84015.1 - 3.5e-25 88.1 0.0 8.8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 META domain NlpE PF04170.12 AFI84015.1 - 5.7e-23 81.7 0.1 4.8e-22 78.7 0.1 2.4 2 0 0 2 2 2 1 NlpE N-terminal domain Inh PF02974.14 AFI84015.1 - 0.0048 16.9 0.0 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 Protease inhibitor Inh GreA_GreB PF01272.19 AFI84016.1 - 3.5e-18 65.3 0.1 4.7e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Rnk_N PF14760.6 AFI84016.1 - 3.3e-10 40.3 0.3 4.8e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Rnk N-terminus Kdo PF06293.14 AFI84018.1 - 2.9e-09 36.6 0.0 6.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 AFI84018.1 - 0.0061 15.9 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.9 AFI84018.1 - 0.022 14.3 0.0 0.074 12.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 AFI84018.1 - 0.15 11.0 0.2 0.42 9.5 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Multi_Drug_Res PF00893.19 AFI84020.1 - 9.3e-31 106.4 11.3 1.2e-30 106.0 11.3 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AFI84020.1 - 0.00071 19.8 15.7 0.0011 19.2 15.7 1.3 1 1 0 1 1 1 1 EamA-like transporter family UPF0060 PF02694.15 AFI84020.1 - 0.014 15.7 9.7 0.017 15.3 9.7 1.1 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF2207 PF09972.9 AFI84020.1 - 6.5 5.4 9.4 7.4 5.2 9.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 AFI84021.1 - 6.1e-16 58.6 9.5 2.9e-15 56.5 5.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) YtpI PF14007.6 AFI84021.1 - 0.007 16.5 4.8 0.017 15.3 1.8 2.3 2 1 0 2 2 2 1 YtpI-like protein DUF5336 PF17270.2 AFI84021.1 - 0.055 13.1 2.9 0.21 11.2 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5336) MrpF_PhaF PF04066.13 AFI84021.1 - 0.056 13.8 3.9 0.43 11.0 0.2 2.5 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) MHYT PF03707.16 AFI84021.1 - 0.06 13.5 0.7 0.37 11.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Asp4 PF16996.5 AFI84021.1 - 0.16 11.7 1.6 0.42 10.4 0.1 2.0 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 2OG-FeII_Oxy_3 PF13640.6 AFI84022.1 - 3.8e-07 30.9 0.0 6.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 AFI84022.1 - 1.5e-05 25.6 0.0 2.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.21 AFI84023.1 - 5.8e-17 62.3 0.0 8.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AFI84023.1 - 2.2e-05 24.7 0.0 4.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AFI84023.1 - 0.00027 21.1 0.0 0.0065 16.6 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Peptidase_M20 PF01546.28 AFI84024.1 - 1.1e-26 93.8 0.0 1.6e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AFI84024.1 - 2.1e-10 40.5 0.0 4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Aminotran_3 PF00202.21 AFI84025.1 - 1.3e-77 261.2 0.1 1.6e-77 260.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Cellulase PF00150.18 AFI84025.1 - 0.12 11.8 0.2 0.27 10.6 0.1 1.6 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Peptidase_M24 PF00557.24 AFI84026.1 - 5.3e-33 114.5 0.2 7.5e-33 114.0 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AFI84026.1 - 1.4e-19 71.1 0.0 5.8e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N_2 PF16189.5 AFI84026.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Aldedh PF00171.22 AFI84027.1 - 7.1e-137 456.7 0.0 8.6e-137 456.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AFI84027.1 - 0.00091 18.4 0.0 0.013 14.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 AFI84027.1 - 0.2 11.1 0.1 0.53 9.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ABC_trans_aux PF03886.13 AFI84028.1 - 2.8e-36 124.5 0.2 3.2e-36 124.3 0.2 1.0 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component E2_bind PF08825.10 AFI84028.1 - 0.025 14.7 0.1 0.39 10.9 0.0 2.3 2 1 0 2 2 2 0 E2 binding domain MlaD PF02470.20 AFI84029.1 - 1e-35 121.9 0.0 1.5e-12 47.6 0.0 3.6 3 0 0 3 3 3 3 MlaD protein ALIX_LYPXL_bnd PF13949.6 AFI84029.1 - 0.0024 17.2 0.1 0.0048 16.2 0.1 1.4 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF948 PF06103.11 AFI84029.1 - 0.057 13.7 0.8 18 5.7 0.0 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HisKA_3 PF07730.13 AFI84029.1 - 0.12 12.9 1.1 1.8 9.1 0.3 3.1 1 1 1 2 2 2 0 Histidine kinase DUF1664 PF07889.12 AFI84029.1 - 0.15 12.1 0.4 0.33 11.0 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 AFI84029.1 - 1.5 8.4 3.8 0.51 9.9 1.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) ZapB PF06005.12 AFI84029.1 - 4.2 7.9 5.7 40 4.7 5.7 2.3 1 1 0 1 1 1 0 Cell division protein ZapB PqiA PF04403.13 AFI84030.1 - 2.5e-99 329.5 38.7 1e-59 200.8 11.7 2.0 2 0 0 2 2 2 2 Paraquat-inducible protein A DZR PF12773.7 AFI84030.1 - 0.0059 16.6 2.6 1.5 8.9 0.1 2.4 2 0 0 2 2 2 2 Double zinc ribbon Tmemb_55A PF09788.9 AFI84030.1 - 0.0073 15.4 1.1 0.017 14.2 0.5 2.0 2 0 0 2 2 2 1 Transmembrane protein 55A Spt4 PF06093.13 AFI84030.1 - 0.0077 16.3 0.5 3.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Spt4/RpoE2 zinc finger zinc_ribbon_9 PF14369.6 AFI84030.1 - 0.097 12.9 1.8 0.25 11.7 1.8 1.6 1 0 0 1 1 1 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 AFI84030.1 - 0.11 12.4 5.4 4.1 7.4 0.7 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF2688 PF10892.8 AFI84030.1 - 0.12 11.8 2.7 0.35 10.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) zf-C4_Topoisom PF01396.19 AFI84030.1 - 0.23 11.3 1.5 4.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.6 AFI84030.1 - 0.23 10.9 7.6 0.49 9.9 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2HC5 PF06221.13 AFI84030.1 - 0.26 11.3 2.9 1.4 9.0 0.5 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Nudix_N_2 PF14803.6 AFI84030.1 - 0.36 10.8 0.1 0.36 10.8 0.1 3.8 4 0 0 4 4 4 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 AFI84030.1 - 0.38 10.9 7.2 0.34 11.1 0.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 AFI84030.1 - 0.75 9.8 2.0 29 4.7 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-tcix PF14952.6 AFI84030.1 - 0.94 9.1 4.9 30 4.4 0.1 3.3 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding ADK_lid PF05191.14 AFI84030.1 - 1.8 8.6 4.2 29 4.7 0.2 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 AFI84030.1 - 3.1 7.6 6.1 12 5.8 0.2 2.9 2 1 0 2 2 2 0 zinc-ribbon domain DUF4282 PF14110.6 AFI84033.1 - 1.9e-13 50.9 3.9 1.4e-12 48.2 3.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4282) DUF3040 PF11239.8 AFI84033.1 - 1.6 9.1 4.9 2 8.7 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) PhnA PF03831.14 AFI84034.1 - 9.3e-34 115.1 8.9 1.2e-33 114.8 8.9 1.1 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 AFI84034.1 - 3.2e-14 52.6 7.1 5.8e-14 51.7 7.1 1.4 1 0 0 1 1 1 1 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.10 AFI84034.1 - 3.6e-05 23.4 0.8 6.6e-05 22.5 0.8 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain DUF2318 PF10080.9 AFI84034.1 - 0.0073 16.4 0.3 0.012 15.7 0.3 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2318) OrfB_Zn_ribbon PF07282.11 AFI84034.1 - 0.015 15.2 0.4 0.026 14.4 0.4 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 AFI84034.1 - 0.021 14.7 1.6 0.04 13.8 1.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 UPF0547 PF10571.9 AFI84034.1 - 0.037 14.1 4.5 0.33 11.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 AFI84034.1 - 0.073 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbons RPA_interact_C PF14768.6 AFI84034.1 - 0.089 13.4 0.2 0.11 13.1 0.3 1.5 1 1 0 1 1 1 0 Replication protein A interacting C-terminal PHF5 PF03660.14 AFI84034.1 - 0.11 12.7 1.0 0.16 12.2 0.7 1.7 1 1 0 1 1 1 0 PHF5-like protein Zn_Tnp_IS1 PF03811.13 AFI84034.1 - 0.16 11.7 1.6 2.2 8.1 0.5 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zf-B_box PF00643.24 AFI84034.1 - 0.38 11.0 3.2 0.76 10.0 3.2 1.5 1 1 0 1 1 1 0 B-box zinc finger Zn_Tnp_IS1595 PF12760.7 AFI84034.1 - 0.46 10.5 2.6 5.7 7.0 3.5 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 AFI84034.1 - 0.98 9.7 4.8 11 6.4 0.2 2.5 1 1 1 2 2 2 0 zinc-ribbon HTH_20 PF12840.7 AFI84035.1 - 3.5e-11 43.0 0.0 4.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AFI84035.1 - 5.7e-05 22.9 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 AFI84035.1 - 0.0025 17.6 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_34 PF13601.6 AFI84035.1 - 0.0038 17.4 0.0 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AFI84035.1 - 0.004 17.0 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AFI84035.1 - 0.072 13.4 0.1 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator DUF4886 PF16227.5 AFI84035.1 - 0.14 11.4 0.0 3.9 6.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4886) ArsP_1 PF03773.13 AFI84036.1 - 1.1e-62 211.9 13.2 1.2e-62 211.7 13.2 1.0 1 0 0 1 1 1 1 Predicted permease Phage_holin_8 PF16931.5 AFI84036.1 - 0.14 12.2 7.4 0.28 11.2 0.1 3.5 3 1 0 3 3 3 0 Putative phage holin UPF0154 PF03672.13 AFI84036.1 - 1.9 8.5 0.0 1.9 8.5 0.0 2.9 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0154) 3-dmu-9_3-mt PF06983.13 AFI84037.1 - 2.4e-39 134.5 0.0 3.1e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 AFI84037.1 - 0.21 11.8 0.0 0.3 11.3 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YCII PF03795.14 AFI84038.1 - 1.7e-23 82.8 0.0 2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain MIase PF02426.16 AFI84038.1 - 0.03 14.5 0.0 0.71 10.1 0.1 2.1 1 1 1 2 2 2 0 Muconolactone delta-isomerase YCII PF03795.14 AFI84039.1 - 4.6e-18 65.4 0.0 8.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 YCII-related domain 3-dmu-9_3-mt PF06983.13 AFI84039.1 - 2.6e-10 40.8 0.0 4.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 AFI84039.1 - 0.001 19.2 0.0 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SnoaL_3 PF13474.6 AFI84040.1 - 1.5e-16 60.7 0.1 1.8e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AFI84040.1 - 1.1e-07 32.0 0.1 1.4e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_2 PF12680.7 AFI84040.1 - 2.5e-07 31.2 0.0 3.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AFI84040.1 - 1.3e-06 28.7 0.0 1.7e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 AFI84040.1 - 0.013 15.6 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 SnoaL-like domain MmlI PF09448.10 AFI84040.1 - 0.026 15.0 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Peptidase_C2 PF00648.21 AFI84040.1 - 0.038 13.0 0.4 0.06 12.4 0.4 1.4 1 1 0 1 1 1 0 Calpain family cysteine protease ComP_DUS PF16732.5 AFI84041.1 - 4.1e-08 34.0 0.1 1.7e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Type IV minor pilin ComP, DNA uptake sequence receptor T2SSG PF08334.11 AFI84041.1 - 7.2e-08 32.5 3.2 3.1e-05 24.0 3.2 3.0 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein G EAL PF00563.20 AFI84042.1 - 9.7e-74 247.9 0.3 2.5e-73 246.5 0.3 1.7 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI84042.1 - 1.2e-49 168.2 0.3 3.1e-49 166.8 0.3 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 AFI84042.1 - 7.1e-12 45.5 0.0 2.3e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 HAMP domain GAF PF01590.26 AFI84042.1 - 0.0095 16.6 0.0 0.044 14.4 0.0 2.1 2 0 0 2 2 2 1 GAF domain Sigma70_r2 PF04542.14 AFI84043.1 - 8.7e-12 44.6 0.2 3e-11 42.9 0.2 2.0 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AFI84043.1 - 3.7e-07 29.7 0.1 1.2e-06 28.1 0.1 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 TPR_7 PF13176.6 AFI84043.1 - 0.0012 18.8 1.5 0.25 11.5 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84043.1 - 0.0016 18.4 2.2 0.27 11.5 0.8 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Sigma70_r4 PF04545.16 AFI84043.1 - 0.0035 16.8 0.9 0.043 13.3 0.4 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 TPR_8 PF13181.6 AFI84043.1 - 0.011 15.9 1.1 0.45 10.9 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AFI84043.1 - 0.096 13.0 6.7 5 7.5 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84043.1 - 0.25 11.2 2.3 1.6 8.7 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AFI84043.1 - 1.7 9.7 11.7 1.4 9.9 2.7 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NAD_binding_10 PF13460.6 AFI84044.1 - 1.8e-42 145.3 0.0 2.1e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AFI84044.1 - 1.6e-15 57.3 0.5 2.7e-14 53.3 0.5 2.1 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 AFI84044.1 - 5.4e-08 32.2 0.1 7e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 AFI84044.1 - 9.1e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AFI84044.1 - 6.5e-05 22.2 0.0 0.056 12.6 0.0 2.4 1 1 2 3 3 3 2 Male sterility protein Semialdhyde_dh PF01118.24 AFI84044.1 - 9.8e-05 22.8 0.1 0.00043 20.7 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 AFI84044.1 - 0.0011 19.1 1.0 0.0021 18.2 0.3 1.8 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Biotin_carb_N PF00289.22 AFI84044.1 - 0.0022 18.5 0.1 1.2 9.7 0.0 2.9 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Polysacc_synt_2 PF02719.15 AFI84044.1 - 0.0083 15.3 0.0 0.74 8.9 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AFI84044.1 - 0.018 14.2 0.1 0.032 13.4 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain ApbA PF02558.16 AFI84044.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 AFI84044.1 - 0.026 14.6 0.7 0.05 13.7 0.7 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 AFI84044.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 AFI84044.1 - 0.07 12.5 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AFI84044.1 - 0.081 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF5610 PF18433.1 AFI84045.1 - 2.1e-37 128.2 0.3 3.1e-37 127.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5610) MFS_1 PF07690.16 AFI84046.1 - 8e-23 80.9 56.5 1.5e-15 57.0 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2238 PF09997.9 AFI84048.1 - 0.0029 17.4 7.5 0.0041 16.9 5.6 2.2 1 1 0 1 1 1 1 Predicted membrane protein (DUF2238) 60KD_IMP PF02096.20 AFI84048.1 - 2.1 8.2 7.8 7.6 6.4 7.8 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein DUF2070 PF09843.9 AFI84048.1 - 6.5 4.9 9.8 7.6 4.7 9.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) His_Phos_1 PF00300.22 AFI84049.1 - 7.5e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MS_channel PF00924.18 AFI84050.1 - 3.8e-33 114.8 1.1 3.8e-33 114.8 1.1 2.8 4 0 0 4 4 4 1 Mechanosensitive ion channel CENP-H PF05837.12 AFI84050.1 - 0.1 13.0 0.3 0.23 11.9 0.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3658 PF12395.8 AFI84051.1 - 0.029 14.3 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DEAD PF00270.29 AFI84054.1 - 9e-49 165.6 0.2 1.8e-48 164.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI84054.1 - 2.1e-31 108.5 0.0 7.7e-31 106.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 AFI84054.1 - 2.6e-23 81.8 1.1 1.1e-22 79.8 0.1 2.5 3 0 0 3 3 3 1 DbpA RNA binding domain ResIII PF04851.15 AFI84054.1 - 2.5e-07 30.9 0.0 1.6e-06 28.3 0.0 2.2 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AFI84054.1 - 0.00084 18.7 0.0 0.0021 17.4 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 AFI84054.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GGDEF PF00990.21 AFI84055.1 - 2.2e-50 170.5 0.1 3.1e-50 170.1 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AFI84055.1 - 2e-15 56.9 0.3 1.8e-14 53.8 0.3 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AFI84055.1 - 0.0018 18.5 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain Sec2p PF06428.11 AFI84055.1 - 0.038 13.9 0.9 0.2 11.6 0.2 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p GGDEF_2 PF17853.1 AFI84055.1 - 0.061 13.6 0.0 0.23 11.8 0.0 1.9 2 1 0 2 2 2 0 GGDEF-like domain PAS PF00989.25 AFI84055.1 - 0.066 13.2 0.0 0.25 11.4 0.0 2.0 1 1 0 1 1 1 0 PAS fold Lactamase_B PF00753.27 AFI84056.1 - 1.1e-17 64.7 0.7 1.1e-16 61.4 0.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AFI84056.1 - 0.00021 20.9 0.4 0.00079 19.0 0.4 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TauE PF01925.19 AFI84057.1 - 8.2e-44 150.0 41.8 9.7e-44 149.8 41.8 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phageshock_PspG PF09583.10 AFI84057.1 - 0.046 14.0 1.2 0.046 14.0 1.2 4.5 4 2 1 5 5 5 0 Phage shock protein G (Phageshock_PspG) BTP PF05232.12 AFI84057.1 - 2.2 8.4 22.0 0.58 10.3 2.2 4.1 4 1 0 4 4 4 0 Chlorhexidine efflux transporter DUF2892 PF11127.8 AFI84058.1 - 8.8e-11 41.7 2.5 1.2e-10 41.2 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) HTH_5 PF01022.20 AFI84059.1 - 4.2e-11 42.5 2.0 6.6e-11 41.9 2.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AFI84059.1 - 6.4e-10 38.9 1.7 1e-09 38.3 1.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AFI84059.1 - 2.7e-05 24.0 0.2 4.9e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 MarR family HxlR PF01638.17 AFI84059.1 - 0.00013 21.8 0.2 0.00033 20.5 0.1 1.7 1 1 0 1 1 1 1 HxlR-like helix-turn-helix Rrf2 PF02082.20 AFI84059.1 - 0.00091 19.5 0.5 0.0016 18.7 0.5 1.6 1 1 0 1 1 1 1 Transcriptional regulator HTH_34 PF13601.6 AFI84059.1 - 0.0028 17.8 0.1 0.0045 17.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 AFI84059.1 - 0.034 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AFI84059.1 - 0.043 13.7 0.1 0.072 13.0 0.1 1.4 1 1 0 1 1 1 0 TFIIE alpha subunit HTH_IclR PF09339.10 AFI84059.1 - 0.043 13.6 1.6 0.087 12.6 1.6 1.6 1 1 0 1 1 1 0 IclR helix-turn-helix domain MgtE_N PF03448.17 AFI84059.1 - 0.11 13.1 0.7 0.2 12.3 0.6 1.5 1 1 0 1 1 1 0 MgtE intracellular N domain CUTL PF16557.5 AFI84059.1 - 0.31 11.2 1.0 5.3 7.3 0.1 2.5 1 1 2 3 3 3 0 CUT1-like DNA-binding domain of SATB tRNA_edit PF04073.15 AFI84060.1 - 2.9e-26 92.0 0.0 3.4e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain UPF0016 PF01169.19 AFI84061.1 - 3e-42 142.8 14.9 7.1e-22 77.5 4.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 AFI84061.1 - 0.0015 18.2 11.9 0.0034 17.1 11.9 1.7 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3681 PF12442.8 AFI84061.1 - 0.064 13.7 0.6 0.064 13.7 0.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3681) DUF1290 PF06947.12 AFI84061.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1290) Tn7_TnsC_Int PF11426.8 AFI84062.1 - 0.07 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Arg_repressor PF01316.21 AFI84062.1 - 0.11 12.3 0.0 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain ThiF PF00899.21 AFI84063.1 - 4.3e-39 134.3 0.0 4.5e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 AFI84063.1 - 0.01 16.2 0.0 0.058 13.8 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 AFI84063.1 - 0.019 15.0 0.5 0.053 13.6 0.2 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AFI84063.1 - 0.024 14.9 0.2 0.12 12.7 0.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AFI84063.1 - 0.044 13.4 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cons_hypoth95 PF03602.15 AFI84063.1 - 0.052 13.2 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NPV_P10 PF05531.12 AFI84063.1 - 0.19 12.2 0.6 1.3 9.5 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3488 PF11992.8 AFI84064.1 - 3.1e-103 345.1 4.9 3.1e-103 345.1 4.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3488) Transglut_core PF01841.19 AFI84064.1 - 5e-28 97.8 0.0 9e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 AFI84064.1 - 0.00051 20.2 0.0 0.0015 18.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Dpy19 PF10034.9 AFI84064.1 - 1.4 7.1 7.5 2.5 6.2 7.5 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF58 PF01882.18 AFI84065.1 - 7.7e-09 35.7 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF58 PGG PF13962.6 AFI84065.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function AAA_3 PF07726.11 AFI84066.1 - 3.5e-63 211.3 0.1 5.4e-63 210.7 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AFI84066.1 - 1.4e-17 63.3 0.3 7.3e-17 61.0 0.0 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 AFI84066.1 - 1.8e-12 47.4 0.0 6.7e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AFI84066.1 - 3.2e-06 27.6 0.0 1.2e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AFI84066.1 - 8.4e-06 25.6 0.1 0.00017 21.3 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AFI84066.1 - 6.9e-05 22.0 0.0 0.0003 20.0 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AFI84066.1 - 0.00034 20.3 0.0 0.0037 17.0 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 AFI84066.1 - 0.0015 18.0 0.1 0.72 9.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AFI84066.1 - 0.035 14.5 0.9 0.15 12.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 AFI84066.1 - 0.055 14.0 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 AFI84066.1 - 0.058 13.5 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase CbiA PF01656.23 AFI84066.1 - 0.085 12.9 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 AFI84066.1 - 0.093 12.9 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AFI84066.1 - 0.095 13.0 0.3 0.39 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain Rubrerythrin PF02915.17 AFI84067.1 - 0.00023 21.6 1.2 0.0003 21.2 0.9 1.3 1 1 0 1 1 1 1 Rubrerythrin Coat_F PF07875.12 AFI84067.1 - 0.00025 21.2 0.1 0.031 14.5 0.0 2.4 1 1 1 2 2 2 1 Coat F domain COQ7 PF03232.13 AFI84067.1 - 0.0042 16.9 0.2 0.0052 16.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 GAD PF02938.14 AFI84067.1 - 0.025 14.8 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 GAD domain Ferritin PF00210.24 AFI84067.1 - 0.035 14.0 2.3 0.058 13.3 2.3 1.3 1 1 0 1 1 1 0 Ferritin-like domain PLN_propep PF16485.5 AFI84067.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Protealysin propeptide TetR_C_31 PF17940.1 AFI84067.1 - 0.096 12.9 0.2 0.18 12.0 0.2 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4621 PF15414.6 AFI84067.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) TatD_DNase PF01026.21 AFI84068.1 - 1.4e-63 214.7 0.0 1.6e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase DUF4203 PF13886.6 AFI84069.1 - 7.9e-05 22.4 2.0 7.9e-05 22.4 2.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) DUF373 PF04123.13 AFI84069.1 - 0.19 11.1 6.2 0.24 10.8 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1774 PF08611.10 AFI84069.1 - 1.4 9.3 8.9 1.4 9.3 3.4 2.2 1 1 0 2 2 2 0 Fungal protein of unknown function (DUF1774) G_glu_transpept PF01019.21 AFI84070.1 - 1.4e-163 545.3 0.2 1.6e-163 545.1 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UPF0176_N PF17773.1 AFI84071.1 - 3e-25 88.4 0.0 5.9e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 AFI84071.1 - 3.9e-11 43.4 0.0 7.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 AFI84071.1 - 6.9e-05 23.1 2.0 0.00016 22.0 2.0 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal zinc_ribbon_9 PF14369.6 AFI84071.1 - 0.047 13.9 2.7 0.11 12.8 2.7 1.6 1 0 0 1 1 1 0 zinc-ribbon DUF3450 PF11932.8 AFI84072.1 - 0.14 11.4 6.7 0.28 10.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) tify PF06200.14 AFI84072.1 - 0.56 9.6 2.9 0.54 9.6 1.4 1.8 1 1 1 2 2 2 0 tify domain Peptidase_M15_2 PF05951.13 AFI84073.1 - 1.6e-59 199.9 0.0 2.2e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 AFI84073.1 - 2.6e-11 43.6 0.0 4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M15 TAT_signal PF10518.9 AFI84073.1 - 0.0012 18.6 0.3 0.0024 17.6 0.3 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence VanY PF02557.17 AFI84073.1 - 0.084 12.7 0.2 1.3 8.8 0.2 2.3 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase FecCD PF01032.18 AFI84074.1 - 3.8e-91 305.3 34.8 4.5e-91 305.1 34.8 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AFI84074.1 - 7.4e-11 42.0 19.1 1.2e-10 41.3 19.1 1.4 1 0 0 1 1 1 1 ABC 3 transport family FAM176 PF14851.6 AFI84074.1 - 0.049 13.3 0.5 0.1 12.2 0.5 1.5 1 0 0 1 1 1 0 FAM176 family ABC_tran PF00005.27 AFI84075.1 - 5.8e-28 98.1 0.0 9.7e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AFI84075.1 - 5.3e-11 42.4 0.1 1.2e-10 41.2 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AFI84075.1 - 7.2e-10 39.2 2.2 4.7e-05 23.4 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AFI84075.1 - 0.0001 22.6 0.2 0.00065 20.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI84075.1 - 0.00033 21.1 0.3 0.0048 17.3 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AFI84075.1 - 0.00049 19.9 3.3 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AFI84075.1 - 0.00052 19.7 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AFI84075.1 - 0.0016 18.9 0.1 0.0042 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AFI84075.1 - 0.0021 18.0 0.3 0.045 13.7 0.0 2.4 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 AFI84075.1 - 0.0038 17.4 0.3 0.025 14.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 AFI84075.1 - 0.0065 15.9 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 AFI84075.1 - 0.0067 16.3 0.2 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 AFI84075.1 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Septin PF00735.18 AFI84075.1 - 0.017 14.4 0.0 0.041 13.1 0.0 1.7 1 1 1 2 2 2 0 Septin AAA_28 PF13521.6 AFI84075.1 - 0.017 15.3 0.2 0.063 13.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AFI84075.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AFI84075.1 - 0.05 13.0 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Spore_IV_A PF09547.10 AFI84075.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) TniB PF05621.11 AFI84075.1 - 0.068 12.6 0.1 3 7.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 AFI84075.1 - 0.093 12.8 0.0 0.31 11.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 AFI84075.1 - 0.1 12.2 0.1 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA PF00004.29 AFI84075.1 - 0.11 13.0 0.2 1.1 9.7 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AFI84075.1 - 0.11 12.1 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AFI84075.1 - 0.11 12.2 0.3 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 AFI84075.1 - 0.13 11.2 0.1 0.5 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 AFI84075.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 AFI84075.1 - 0.15 12.6 0.1 0.47 11.0 0.0 1.9 1 1 0 2 2 2 0 AAA domain Peripla_BP_2 PF01497.18 AFI84076.1 - 1e-27 97.3 0.1 1.2e-27 97.1 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Pribosyltran PF00156.27 AFI84077.1 - 8.9e-20 70.8 0.0 1.1e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PNP_UDP_1 PF01048.20 AFI84078.1 - 5.7e-42 143.6 0.0 6.3e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SIS PF01380.22 AFI84078.1 - 0.015 15.1 0.2 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 SIS domain DUF5613 PF18467.1 AFI84078.1 - 0.19 12.2 0.1 14 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) CsiV PF10972.8 AFI84079.1 - 9.4e-26 91.0 7.7 1.4e-11 44.6 0.6 3.2 1 1 2 3 3 3 3 Peptidoglycan-binding protein, CsiV cPLA2_C2 PF18695.1 AFI84079.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain Band_7 PF01145.25 AFI84080.1 - 6.2e-31 107.8 0.5 6.2e-31 107.8 0.5 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 AFI84080.1 - 3.5e-08 33.4 1.3 7.2e-08 32.4 1.3 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 AFI84080.1 - 0.041 13.6 0.1 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 SPFH domain-Band 7 family Flot PF15975.5 AFI84080.1 - 1 9.6 15.3 0.48 10.6 7.3 2.6 1 1 1 2 2 2 0 Flotillin NfeD PF01957.18 AFI84081.1 - 2.2e-16 60.0 0.0 4.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding DUF4131 PF13567.6 AFI84081.1 - 0.001 18.7 4.6 0.0029 17.3 4.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) His_Phos_1 PF00300.22 AFI84082.1 - 4.6e-44 150.4 0.0 5.6e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4110 PF13422.6 AFI84082.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Cupin_4 PF08007.12 AFI84083.1 - 1.7e-78 264.3 3.1 2.1e-78 264.0 3.1 1.1 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.19 AFI84083.1 - 0.00039 20.3 0.1 0.0011 18.8 0.1 1.8 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.6 AFI84083.1 - 0.00044 20.0 0.5 0.0071 16.1 0.2 2.6 1 1 1 3 3 3 1 Cupin-like domain Cupin_1 PF00190.22 AFI84083.1 - 0.0039 16.8 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.11 AFI84083.1 - 0.067 12.9 0.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Cupin domain DUF1451 PF07295.11 AFI84084.1 - 3.7e-52 176.3 0.2 4.6e-52 176.0 0.2 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 AFI84084.1 - 0.0042 17.2 1.0 0.012 15.7 1.0 1.8 1 0 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 AFI84084.1 - 0.025 14.6 0.3 0.048 13.7 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain HypA PF01155.19 AFI84084.1 - 0.034 14.2 1.6 0.046 13.7 0.6 1.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 AFI84084.1 - 0.038 14.0 0.4 0.067 13.2 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 AFI84084.1 - 0.056 13.1 2.8 0.095 12.4 2.8 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain CdiA_C_tRNase PF18664.1 AFI84084.1 - 0.066 13.4 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain PADR1 PF08063.12 AFI84084.1 - 0.073 12.9 1.5 0.13 12.1 0.2 1.9 1 1 1 2 2 2 0 PADR1 (NUC008) domain DALR_1 PF05746.15 AFI84084.1 - 0.09 13.0 1.3 0.15 12.2 1.3 1.4 1 1 0 1 1 1 0 DALR anticodon binding domain zf-RRN7 PF11781.8 AFI84084.1 - 0.22 11.2 2.5 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF349 PF03993.12 AFI84084.1 - 0.26 11.6 2.3 0.57 10.5 2.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DsbB PF02600.16 AFI84085.1 - 2.7e-40 138.2 10.6 3e-40 138.0 10.6 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB Jiraiya PF15038.6 AFI84085.1 - 0.018 14.5 3.2 0.018 14.5 3.2 1.5 1 1 0 1 1 1 0 Jiraiya eIF-1a PF01176.19 AFI84086.1 - 9.7e-27 92.6 0.1 1.1e-26 92.4 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 AFI84086.1 - 3.8e-05 23.4 0.0 5.5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 AFI84086.1 - 0.00073 19.8 0.1 0.00087 19.6 0.1 1.1 1 0 0 1 1 1 1 S1 RNA binding domain RNase_II_C_S1 PF18614.1 AFI84086.1 - 0.013 15.4 0.0 0.099 12.6 0.0 2.1 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Myosin_N PF02736.19 AFI84086.1 - 0.038 13.8 0.1 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain ATE_C PF04377.15 AFI84087.1 - 1.9e-38 132.1 0.3 2.5e-38 131.7 0.3 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 AFI84087.1 - 5e-20 71.7 0.6 8.3e-20 71.0 0.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 AFI84087.1 - 1e-05 25.7 0.1 2e-05 24.8 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Leu_Phe_trans PF03588.14 AFI84088.1 - 9.3e-76 253.0 0.1 1.1e-75 252.8 0.1 1.1 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 AFI84088.1 - 0.098 12.8 0.0 0.51 10.5 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain HDOD PF08668.12 AFI84089.1 - 1.3e-19 70.4 0.0 2.6e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 HDOD domain Toprim_4 PF13662.6 AFI84090.1 - 1.1e-24 86.7 0.0 2.7e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 Toprim domain RecR PF02132.15 AFI84090.1 - 5.5e-12 45.1 2.9 1.2e-11 43.9 2.9 1.6 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AFI84090.1 - 3.8e-10 39.9 0.0 1.2e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Toprim domain HHH PF00633.23 AFI84090.1 - 0.038 13.9 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 AFI84090.1 - 0.065 13.9 0.0 0.36 11.5 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain YbaB_DNA_bd PF02575.16 AFI84091.1 - 4e-34 116.7 11.9 4.5e-34 116.5 11.9 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family NDUF_B5 PF09781.9 AFI84091.1 - 0.0035 17.0 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit PIN_8 PF18476.1 AFI84091.1 - 0.042 13.7 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 PIN like domain MmoB_DmpM PF02406.17 AFI84091.1 - 0.052 13.7 0.4 0.088 13.0 0.2 1.5 1 1 0 1 1 1 0 MmoB/DmpM family AMIN PF11741.8 AFI84091.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AMIN domain Endotoxin_C2 PF18449.1 AFI84091.1 - 1.3 9.4 7.8 10 6.6 1.8 2.2 2 0 0 2 2 2 0 Delta endotoxin DNA_pol3_delta2 PF13177.6 AFI84092.1 - 3.8e-43 147.1 0.0 7.2e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 AFI84092.1 - 9.8e-29 100.1 2.6 9.8e-29 100.1 2.6 1.9 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_tau_5 PF12170.8 AFI84092.1 - 8.1e-16 58.4 6.6 8.1e-16 58.4 6.6 1.9 2 0 0 2 2 1 1 DNA polymerase III tau subunit V interacting with alpha AAA PF00004.29 AFI84092.1 - 2.9e-13 50.4 0.1 7e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AFI84092.1 - 3.9e-07 29.9 0.0 9.9e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AFI84092.1 - 1.9e-06 28.2 1.3 7.2e-05 23.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 AFI84092.1 - 2.4e-05 24.9 0.0 0.00014 22.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AFI84092.1 - 6.4e-05 23.0 0.1 0.59 10.1 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AFI84092.1 - 8.9e-05 22.5 0.1 0.00062 19.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 AFI84092.1 - 9e-05 22.5 0.2 0.0014 18.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AFI84092.1 - 0.00025 21.5 11.1 0.0037 17.7 0.1 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 AFI84092.1 - 0.00072 19.3 0.0 0.0035 17.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 AFI84092.1 - 0.0012 18.2 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_assoc_2 PF16193.5 AFI84092.1 - 0.0013 19.0 0.3 0.0078 16.5 0.3 2.5 1 1 0 1 1 1 1 AAA C-terminal domain TsaE PF02367.17 AFI84092.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 AFI84092.1 - 0.01 15.2 0.0 0.048 13.1 0.0 2.1 1 1 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 AFI84092.1 - 0.013 15.2 0.0 0.043 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 AFI84092.1 - 0.018 14.6 0.0 0.2 11.2 0.0 2.4 1 1 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 AFI84092.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 AFI84092.1 - 0.042 14.4 0.3 0.55 10.7 0.0 2.7 3 0 0 3 3 3 0 ABC transporter DNA_pol3_delta PF06144.13 AFI84092.1 - 0.049 13.4 2.1 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 AFI84092.1 - 0.062 12.7 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3646 PF12362.8 AFI84092.1 - 0.13 12.6 1.0 0.28 11.5 1.0 1.7 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal SKI PF01202.22 AFI84092.1 - 0.16 12.1 0.3 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase ATPase PF06745.13 AFI84092.1 - 0.17 11.2 0.1 24 4.2 0.0 2.5 2 0 0 2 2 2 0 KaiC Pan_kinase PF03309.14 AFI84093.1 - 4.8e-52 176.8 1.3 5.9e-52 176.5 1.3 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase BPL_LplA_LipB PF03099.19 AFI84094.1 - 1.3e-14 54.3 0.1 1.9e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 AFI84094.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF2069 PF09842.9 AFI84096.1 - 1.8e-30 105.2 8.8 2.1e-30 105.0 8.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2069) FMN_red PF03358.15 AFI84097.1 - 2.8e-10 40.2 0.0 3.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AFI84097.1 - 0.0028 17.4 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold ArsC PF03960.15 AFI84098.1 - 5.8e-21 74.3 0.7 6.9e-21 74.0 0.7 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AFI84098.1 - 0.0038 17.4 0.0 0.34 11.1 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin DUF1687 PF07955.11 AFI84098.1 - 0.025 15.0 0.4 0.05 14.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) TFIIE_beta PF02186.15 AFI84098.1 - 0.034 14.4 0.7 0.29 11.4 0.7 2.2 1 1 0 1 1 1 0 TFIIE beta subunit core domain DUF4760 PF15956.5 AFI84098.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) TPR_19 PF14559.6 AFI84099.1 - 7.3e-10 39.2 12.3 0.00084 19.8 0.3 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat Rubredoxin_2 PF18073.1 AFI84099.1 - 6.8e-09 35.3 6.0 1e-08 34.7 6.0 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain TPR_14 PF13428.6 AFI84099.1 - 1.2e-08 35.0 11.9 0.19 12.6 0.2 7.6 3 3 5 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI84099.1 - 7e-07 29.4 4.6 0.66 10.2 0.0 4.3 2 1 4 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 AFI84099.1 - 9e-07 29.4 1.7 0.035 14.8 0.0 4.0 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AFI84099.1 - 3e-06 27.5 4.8 4.4 8.1 0.0 6.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 AFI84099.1 - 0.00013 21.8 5.2 0.0026 17.7 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 AFI84099.1 - 0.00073 19.8 14.7 0.21 11.9 0.0 5.1 3 3 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84099.1 - 0.0082 16.2 10.7 19 5.7 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84099.1 - 0.031 14.1 7.6 43 4.2 0.0 6.0 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 AFI84099.1 - 0.05 14.0 0.3 8.3 7.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3958 PF13125.6 AFI84099.1 - 0.11 12.7 5.2 0.31 11.3 1.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Glyco_hydro_92 PF07971.12 AFI84099.1 - 0.13 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 TPR_21 PF09976.9 AFI84099.1 - 0.72 9.5 5.1 3.6 7.3 0.3 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 AFI84099.1 - 2.6 8.0 8.8 22 5.1 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat LapA_dom PF06305.11 AFI84100.1 - 7e-16 57.8 1.7 7e-16 57.8 1.7 1.9 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF1043 PF06295.12 AFI84100.1 - 0.0059 16.6 0.1 0.0094 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) FtsL PF04999.13 AFI84100.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.0 1 1 0 2 2 2 0 Cell division protein FtsL Oxidored_q4 PF00507.19 AFI84100.1 - 3.5 7.8 8.3 4.6 7.5 8.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3470 PF11953.8 AFI84101.1 - 3.4e-19 68.5 1.3 4.7e-19 68.1 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 AFI84101.1 - 3.9e-09 35.9 19.2 1.3e-06 28.0 5.0 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AFI84101.1 - 9e-08 32.1 7.6 8.6e-05 22.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI84101.1 - 1.4e-06 28.1 18.7 8.9e-05 22.4 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AFI84101.1 - 3.6e-06 27.0 12.3 0.0011 19.1 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI84101.1 - 8.1e-06 26.3 15.6 4.2e-05 24.0 15.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI84101.1 - 1e-05 25.3 14.0 0.01 15.9 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AFI84101.1 - 2.6e-05 25.0 11.5 0.0061 17.5 1.3 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AFI84101.1 - 3.1e-05 24.4 6.5 0.0039 17.7 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI84101.1 - 4.7e-05 23.5 24.6 0.00069 19.7 14.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI84101.1 - 0.0002 21.8 7.2 0.0057 17.1 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI84101.1 - 0.00058 20.2 14.2 0.08 13.5 1.4 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.6 AFI84101.1 - 0.09 12.9 6.2 0.14 12.3 6.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AFI84101.1 - 0.41 11.2 19.5 0.3 11.7 7.8 2.4 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AFI84101.1 - 1.7 9.7 18.8 1.8 9.7 6.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 AFI84101.1 - 2.6 8.9 12.2 0.64 10.8 3.8 2.5 2 1 0 2 2 2 0 4Fe-4S single cluster domain Sigma70_r2 PF04542.14 AFI84102.1 - 1.9e-18 66.0 0.0 5.1e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI84102.1 - 2.4e-15 55.8 2.1 3.4e-15 55.3 0.2 2.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AFI84102.1 - 2.5e-05 24.2 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 UCR_14kD PF02271.16 AFI84102.1 - 0.015 15.2 0.4 0.12 12.4 0.0 2.6 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit 2Fe-2S_thioredx PF01257.19 AFI84102.1 - 0.026 14.4 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin FtsX_ECD PF18075.1 AFI84103.1 - 4.5e-15 56.1 0.2 7.3e-15 55.4 0.2 1.3 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 AFI84103.1 - 0.017 15.6 3.4 0.017 15.6 3.4 2.9 3 0 0 3 3 3 0 FtsX-like permease family Ninjurin PF04923.12 AFI84103.1 - 0.21 11.6 1.7 15 5.6 0.4 2.5 2 0 0 2 2 2 0 Ninjurin DUF973 PF06157.11 AFI84103.1 - 4 6.4 9.6 0.46 9.5 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF1418 PF07214.12 AFI84103.1 - 5.5 6.9 6.3 0.4 10.5 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) ABC_tran PF00005.27 AFI84104.1 - 1.8e-32 112.8 0.0 2.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI84104.1 - 1e-10 41.9 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AFI84104.1 - 0.00014 21.8 0.1 0.00041 20.3 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 AFI84104.1 - 0.00027 20.6 0.1 0.00045 19.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI84104.1 - 0.0003 21.2 0.1 0.00093 19.6 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AFI84104.1 - 0.0013 18.3 0.0 0.15 11.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 AFI84104.1 - 0.003 17.0 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AFI84104.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AFI84104.1 - 0.014 15.9 0.1 0.023 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AFI84104.1 - 0.016 14.8 0.1 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AFI84104.1 - 0.019 15.2 0.1 0.069 13.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AFI84104.1 - 0.054 13.6 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AFI84104.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 AFI84104.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AFI84104.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.6 2 0 0 2 2 2 0 NACHT domain PIF1 PF05970.14 AFI84104.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase SRP54 PF00448.22 AFI84105.1 - 1.6e-79 266.1 4.7 1.6e-79 266.1 4.7 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 AFI84105.1 - 9.9e-12 44.9 0.7 2.5e-11 43.6 0.3 2.0 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 AFI84105.1 - 7.3e-06 25.4 0.1 1.2e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 AFI84105.1 - 7.9e-05 23.1 0.9 0.00015 22.2 0.2 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 AFI84105.1 - 9.2e-05 22.2 1.3 0.00018 21.3 1.3 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AFI84105.1 - 0.00042 20.7 0.4 0.0012 19.2 0.2 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AFI84105.1 - 0.00058 20.0 0.3 0.0012 19.0 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.6 AFI84105.1 - 0.00081 19.4 0.4 0.0015 18.5 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI84105.1 - 0.0009 19.5 1.4 0.0023 18.2 0.4 2.1 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AFI84105.1 - 0.0009 19.2 0.1 0.0034 17.3 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase CbiA PF01656.23 AFI84105.1 - 0.0011 19.1 0.1 0.0026 17.8 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 AFI84105.1 - 0.0015 19.1 0.8 0.0032 18.0 0.1 1.8 2 0 0 2 2 2 1 ABC transporter MeaB PF03308.16 AFI84105.1 - 0.0035 16.3 0.2 0.0085 15.1 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 AFI84105.1 - 0.006 16.7 1.3 0.035 14.2 0.4 2.4 2 2 0 2 2 2 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 AFI84105.1 - 0.017 14.8 0.4 0.058 13.1 0.2 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 AFI84105.1 - 0.02 15.5 0.1 0.13 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain DSBA PF01323.20 AFI84105.1 - 0.023 14.5 1.8 0.047 13.5 1.8 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_14 PF13173.6 AFI84105.1 - 0.03 14.3 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AFI84105.1 - 0.039 14.3 1.5 0.099 13.0 0.3 2.3 1 1 1 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 AFI84105.1 - 0.04 13.2 0.5 0.057 12.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 AFI84105.1 - 0.062 13.0 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AFI84105.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ArsA_ATPase PF02374.15 AFI84105.1 - 0.14 11.3 2.1 1.2 8.2 2.1 2.1 1 1 0 1 1 1 0 Anion-transporting ATPase ATP_bind_1 PF03029.17 AFI84105.1 - 0.14 11.9 0.4 0.55 10.0 0.2 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 AFI84105.1 - 0.16 11.8 1.0 0.75 9.7 0.4 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AFI84105.1 - 0.31 10.9 2.6 2.3 8.1 0.9 2.3 1 1 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 AFI84105.1 - 0.46 9.3 5.1 0.64 8.9 0.7 2.6 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Peptidase_M16_C PF05193.21 AFI84106.1 - 1.7e-32 113.0 0.0 6.4e-32 111.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AFI84106.1 - 1e-25 90.4 0.0 5.1e-25 88.2 0.0 2.0 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) DUF438 PF04282.13 AFI84106.1 - 0.11 12.5 0.6 4.1 7.4 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF438) Peptidase_M16_C PF05193.21 AFI84107.1 - 7.9e-34 117.3 0.0 4.1e-29 101.9 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AFI84107.1 - 7.1e-14 52.0 0.0 2e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Acyl_transf_2 PF02273.15 AFI84107.1 - 0.17 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase Cons_hypoth95 PF03602.15 AFI84108.1 - 1.1e-47 162.0 0.0 1.2e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AFI84108.1 - 1.1e-07 31.6 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.15 AFI84108.1 - 7.4e-06 25.8 0.1 0.00068 19.4 0.0 2.1 1 1 1 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 AFI84108.1 - 0.0013 18.3 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 AFI84108.1 - 0.003 16.8 0.0 0.0032 16.7 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 AFI84108.1 - 0.0056 16.5 0.0 0.0073 16.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AFI84108.1 - 0.0089 15.7 0.1 0.34 10.6 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 AFI84108.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SAM_MT PF04445.13 AFI84108.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase CTP_transf_like PF01467.26 AFI84109.1 - 2.8e-19 69.7 0.0 3.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AFI84109.1 - 1.1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.4 1 1 1 2 2 2 1 Citrate lyase ligase C-terminal domain Fer4 PF00037.27 AFI84110.1 - 5.9e-10 38.5 23.5 2.1e-06 27.3 4.2 3.2 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_7 PF12838.7 AFI84110.1 - 1.5e-06 28.7 14.9 1.6e-05 25.4 15.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI84110.1 - 1.3e-05 25.2 12.8 2.1e-05 24.6 12.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI84110.1 - 1.3e-05 25.2 22.6 0.00042 20.4 12.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI84110.1 - 1.5e-05 24.8 13.9 0.0024 17.8 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AFI84110.1 - 2.7e-05 25.0 12.8 0.011 16.6 5.4 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AFI84110.1 - 0.00012 22.0 18.6 0.03 14.4 3.4 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain GF_recep_IV PF14843.6 AFI84110.1 - 0.00065 19.5 9.5 0.00093 19.0 9.5 1.3 1 1 0 1 1 1 1 Growth factor receptor domain IV Fer4_4 PF12800.7 AFI84110.1 - 0.0031 17.9 17.0 0.0076 16.7 2.9 2.8 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 AFI84110.1 - 0.0099 16.0 19.9 0.043 13.9 19.9 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AFI84110.1 - 0.014 16.3 20.7 0.28 12.2 7.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AFI84110.1 - 0.12 13.0 4.2 0.12 13.0 4.2 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI84110.1 - 0.64 10.5 14.5 0.35 11.3 3.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_11 PF13247.6 AFI84110.1 - 0.88 9.7 10.9 0.22 11.7 3.3 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Histone_HNS PF00816.21 AFI84111.1 - 1.1e-12 48.6 10.3 5.4e-12 46.4 10.3 1.9 1 1 0 1 1 1 1 H-NS histone family F420_ligase PF01996.16 AFI84111.1 - 0.034 13.5 0.2 0.04 13.3 0.2 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase DUF2362 PF10154.9 AFI84111.1 - 0.048 12.6 0.6 0.053 12.5 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Ribosomal_L29 PF00831.23 AFI84111.1 - 0.059 13.3 5.3 0.13 12.3 5.3 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein HTH_26 PF13443.6 AFI84111.1 - 0.11 12.9 0.9 0.2 12.1 0.9 1.6 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3499 PF12005.8 AFI84111.1 - 0.12 13.0 1.8 0.19 12.3 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) tRNA-synt_1 PF00133.22 AFI84112.1 - 5.4e-81 272.6 5.4 6.9e-27 93.9 1.5 5.1 1 1 3 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 AFI84112.1 - 2.4e-80 268.4 0.0 3.6e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 AFI84112.1 - 2.6e-31 108.7 0.0 3e-19 69.0 0.0 4.5 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AFI84112.1 - 6.3e-16 58.7 0.0 1.5e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AFI84112.1 - 1.6e-06 27.7 0.0 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AFI84112.1 - 0.00011 21.3 0.0 0.097 11.6 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 AFI84112.1 - 0.0021 17.1 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) LptE PF04390.12 AFI84113.1 - 2.2e-11 44.4 1.2 2.6e-11 44.1 1.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly DNA_pol3_delta PF06144.13 AFI84114.1 - 4.9e-26 91.6 0.0 6.5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delt_C PF14840.6 AFI84114.1 - 0.00069 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Processivity clamp loader gamma complex DNA pol III C-term Aldedh PF00171.22 AFI84115.1 - 4.8e-24 84.7 1.7 7.9e-17 60.9 0.9 2.2 1 1 0 2 2 2 2 Aldehyde dehydrogenase family FlgT_N PF16548.5 AFI84115.1 - 0.19 12.3 2.6 0.24 12.0 0.1 2.4 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain CTP_transf_like PF01467.26 AFI84116.1 - 5.1e-28 98.1 0.0 6.1e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Suppressor_APC PF11414.8 AFI84116.1 - 0.075 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF218 PF02698.17 AFI84117.1 - 2.6e-26 92.2 0.0 3.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain RsfS PF02410.15 AFI84118.1 - 6.5e-28 97.1 0.1 8.1e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF3243 PF11588.8 AFI84118.1 - 0.00056 20.2 0.1 0.0019 18.5 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3243) DUF3403 PF11883.8 AFI84118.1 - 0.16 12.1 0.2 0.56 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) SPOUT_MTase PF02590.17 AFI84119.1 - 1.5e-53 180.9 0.0 1.7e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase Maf PF02545.14 AFI84120.1 - 5.6e-55 185.7 0.1 6.2e-55 185.5 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein RNase_E_G PF10150.9 AFI84121.1 - 2e-101 339.0 0.0 2.9e-101 338.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AFI84121.1 - 4e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain F-box-like_2 PF13013.6 AFI84121.1 - 0.02 14.9 0.1 0.059 13.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain DUF4809 PF16067.5 AFI84121.1 - 0.13 12.4 0.2 0.28 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) DUF3971 PF13116.6 AFI84122.1 - 2.6e-53 181.5 0.5 2.6e-53 181.5 0.5 3.3 3 0 0 3 3 3 1 Protein of unknown function AsmA_2 PF13502.6 AFI84122.1 - 7.9e-49 166.2 3.7 7.9e-49 166.2 3.7 5.0 4 1 1 5 5 5 2 AsmA-like C-terminal region PmbA_TldD PF01523.16 AFI84123.1 - 1.6e-68 231.5 0.1 2.9e-68 230.7 0.0 1.4 2 0 0 2 2 2 1 Putative modulator of DNA gyrase TusA PF01206.17 AFI84124.1 - 7.8e-20 70.5 0.1 8.5e-20 70.4 0.1 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA SH3_3 PF08239.11 AFI84124.1 - 0.0086 16.3 0.0 0.043 14.1 0.0 1.8 1 1 1 2 2 2 1 Bacterial SH3 domain Gln-synt_C PF00120.24 AFI84125.1 - 1.2e-139 465.2 0.0 1.4e-139 464.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AFI84125.1 - 3.4e-32 110.0 0.5 7.4e-32 108.9 0.5 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fea1 PF07692.11 AFI84125.1 - 0.14 11.2 0.0 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Low iron-inducible periplasmic protein DUF4124 PF13511.6 AFI84126.1 - 5.6e-15 55.4 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) HATPase_c PF02518.26 AFI84127.1 - 1.7e-15 57.5 0.0 3.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84127.1 - 5.5e-14 52.0 1.6 1.3e-13 50.8 0.4 2.2 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AFI84127.1 - 3.6e-05 23.7 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI84127.1 - 9.3e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI84127.1 - 0.0025 17.8 0.0 0.0076 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AFI84127.1 - 0.01 15.7 0.0 0.035 14.0 0.0 1.9 1 1 0 1 1 1 0 GHKL domain PAS_9 PF13426.7 AFI84127.1 - 0.012 15.8 0.0 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 PAS domain DUF1688 PF07958.11 AFI84127.1 - 0.019 13.7 0.6 0.028 13.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) PAS_7 PF12860.7 AFI84127.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold Syntaxin_2 PF14523.6 AFI84127.1 - 0.083 13.3 0.5 0.52 10.7 0.2 2.3 1 1 1 2 2 2 0 Syntaxin-like protein DUF2664 PF10867.8 AFI84127.1 - 0.46 11.0 3.5 0.51 10.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Sigma54_activat PF00158.26 AFI84128.1 - 3.6e-72 241.5 0.1 5.4e-72 241.0 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AFI84128.1 - 4e-27 94.6 0.0 8.9e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AFI84128.1 - 3.7e-25 88.7 0.0 1.9e-24 86.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AFI84128.1 - 6.8e-14 51.4 1.4 2.1e-12 46.6 0.8 2.7 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI84128.1 - 1.6e-07 31.4 0.0 3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AFI84128.1 - 0.00059 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AFI84128.1 - 0.00095 19.6 0.0 0.0043 17.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI84128.1 - 0.0096 15.3 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 AFI84128.1 - 0.031 13.4 0.0 0.072 12.2 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 AFI84128.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FleQ PF06490.11 AFI84128.1 - 0.16 12.3 0.0 0.83 10.0 0.0 2.2 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ DUF150 PF02576.17 AFI84129.1 - 5.9e-27 93.9 0.1 9e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 AFI84129.1 - 1.8e-18 66.4 0.0 2.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 RimP C-terminal SH3 domain NusA_N PF08529.11 AFI84130.1 - 3.2e-36 124.3 4.4 3.2e-36 124.3 4.4 1.9 2 0 0 2 2 2 1 NusA N-terminal domain KH_5 PF13184.6 AFI84130.1 - 9.3e-28 96.1 0.0 2.9e-26 91.4 0.0 2.5 2 0 0 2 2 2 1 NusA-like KH domain HHH_5 PF14520.6 AFI84130.1 - 8.6e-11 42.3 1.8 1.6e-08 35.0 0.8 3.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain S1 PF00575.23 AFI84130.1 - 6.7e-06 26.4 0.0 1.7e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain KH_2 PF07650.17 AFI84130.1 - 0.00041 20.1 0.0 0.0054 16.5 0.0 2.7 2 0 0 2 2 2 1 KH domain S1_2 PF13509.6 AFI84130.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 S1 domain DUF4332 PF14229.6 AFI84130.1 - 0.059 13.6 0.1 0.8 10.0 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4332) HHH_2 PF12826.7 AFI84130.1 - 0.099 12.8 2.0 5.5 7.2 0.3 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 AFI84130.1 - 0.1 12.4 0.1 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain GTP_EFTU PF00009.27 AFI84131.1 - 1.6e-34 119.1 2.2 1.6e-34 119.1 2.2 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AFI84131.1 - 1.1e-32 112.2 0.7 4.3e-32 110.4 0.7 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 AFI84131.1 - 2.8e-25 87.9 4.0 5.7e-15 54.9 0.2 3.0 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 AFI84131.1 - 8.3e-13 48.5 3.6 1.8e-05 25.1 0.2 4.0 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_assoc PF08364.11 AFI84131.1 - 1e-12 48.1 10.1 1e-12 48.1 10.1 2.5 2 0 0 2 2 2 1 Bacterial translation initiation factor IF-2 associated region MMR_HSR1 PF01926.23 AFI84131.1 - 7e-09 35.8 0.2 7e-09 35.8 0.2 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI84131.1 - 4.4e-05 23.1 0.0 0.00014 21.5 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 AFI84131.1 - 6e-05 22.6 1.0 0.00016 21.2 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 AFI84131.1 - 0.00072 19.2 0.0 0.0024 17.5 0.0 1.9 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AFI84131.1 - 0.1 12.8 0.1 0.31 11.3 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_M23 PF01551.22 AFI84131.1 - 0.13 12.5 0.7 2.4 8.5 0.3 3.3 2 1 0 2 2 2 0 Peptidase family M23 RBFA PF02033.18 AFI84132.1 - 4e-31 107.6 0.0 4.7e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A TruB_N PF01509.18 AFI84133.1 - 1.1e-58 197.9 0.0 1.5e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AFI84133.1 - 2.2e-12 47.0 0.4 4.4e-12 46.0 0.4 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AFI84133.1 - 2.7e-09 36.9 0.1 7.2e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Pseudouridine synthase II TruB, C-terminal Ribosomal_S15 PF00312.22 AFI84134.1 - 8e-37 125.3 0.8 9e-37 125.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RNase_PH PF01138.21 AFI84135.1 - 1.9e-44 151.3 0.0 3.5e-21 76.1 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 S1 PF00575.23 AFI84135.1 - 8.6e-21 74.1 1.6 2.2e-20 72.7 1.6 1.8 1 0 0 1 1 1 1 S1 RNA binding domain PNPase PF03726.14 AFI84135.1 - 4.3e-20 72.0 0.4 1.6e-19 70.2 0.4 2.1 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_PH_C PF03725.15 AFI84135.1 - 2.1e-19 69.3 3.0 4.1e-11 42.8 0.0 3.0 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 AFI84135.1 - 7.1e-14 51.4 1.0 4.1e-11 42.5 1.0 2.9 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 AFI84135.1 - 6.6e-05 22.7 0.1 0.00024 20.9 0.1 2.0 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AFI84135.1 - 0.047 13.6 1.4 0.089 12.7 0.2 2.1 2 0 0 2 2 2 0 KH domain S1_2 PF13509.6 AFI84135.1 - 0.13 12.3 0.0 0.55 10.3 0.0 2.1 1 1 0 1 1 1 0 S1 domain SBP_bac_11 PF13531.6 AFI84136.1 - 1.4e-33 116.6 0.1 1.6e-33 116.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AFI84136.1 - 0.0027 17.7 0.0 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AFI84136.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AFI84137.1 - 3.9e-23 82.2 10.1 5.4e-23 81.7 10.1 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AFI84138.1 - 1.8e-33 116.0 0.0 3.6e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI84138.1 - 2.6e-09 37.3 0.0 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AFI84138.1 - 3.3e-06 27.4 0.1 1.1e-05 25.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI84138.1 - 8.2e-05 23.1 0.1 0.00026 21.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 AFI84138.1 - 0.00029 20.3 0.1 0.27 10.6 0.2 2.2 2 0 0 2 2 2 2 Bacterial TniB protein SMC_N PF02463.19 AFI84138.1 - 0.00032 20.2 0.0 0.013 15.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 AFI84138.1 - 0.0014 18.8 0.1 0.0055 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AFI84138.1 - 0.002 18.6 0.1 0.034 14.6 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AFI84138.1 - 0.0031 17.2 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AFI84138.1 - 0.0033 17.2 0.1 0.0093 15.7 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AFI84138.1 - 0.01 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AFI84138.1 - 0.02 15.1 0.2 0.41 10.9 0.1 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 AFI84138.1 - 0.032 13.4 0.0 0.084 12.1 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 AFI84138.1 - 0.035 14.4 1.2 0.15 12.4 1.2 2.3 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 AFI84138.1 - 0.037 14.0 0.0 0.087 12.7 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 AFI84138.1 - 0.056 13.4 0.3 0.82 9.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AFI84138.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 AFI84138.1 - 0.11 12.0 0.2 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AFI84138.1 - 0.16 12.5 0.2 0.83 10.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 AFI84138.1 - 0.21 10.7 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit MotA_ExbB PF01618.16 AFI84139.1 - 9.8e-33 112.6 0.2 1.3e-32 112.2 0.2 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AFI84140.1 - 2.7e-13 50.2 0.1 3.3e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR ExbD PF02472.16 AFI84141.1 - 5.3e-23 81.6 4.1 6.5e-23 81.3 4.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR Sulf_transp PF04143.14 AFI84141.1 - 0.16 11.5 0.1 0.19 11.3 0.1 1.1 1 0 0 1 1 1 0 Sulphur transport TonB_C PF03544.14 AFI84142.1 - 9e-19 67.7 0.3 4.3e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AFI84142.1 - 3.8e-11 43.1 0.0 1.7e-10 41.0 0.0 2.1 1 1 1 2 2 2 1 TonB C terminal AdHead_fibreRBD PF16812.5 AFI84142.1 - 0.013 15.3 1.0 0.042 13.7 0.2 1.9 1 1 1 2 2 2 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Ndc1_Nup PF09531.10 AFI84142.1 - 2.9 6.5 5.1 3.1 6.4 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF815 PF05673.13 AFI84143.1 - 5.2e-97 323.9 0.0 5.8e-97 323.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 AFI84143.1 - 3.7e-07 30.7 1.9 3e-06 27.7 1.9 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AFI84143.1 - 0.00032 21.1 0.0 0.0011 19.4 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AFI84143.1 - 0.011 15.3 0.0 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 AFI84143.1 - 0.011 15.4 0.2 0.068 12.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 AFI84143.1 - 0.012 15.7 0.1 0.22 11.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 AFI84143.1 - 0.014 14.4 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 AFI84143.1 - 0.03 14.6 0.0 0.063 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 AFI84143.1 - 0.04 13.6 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 AFI84143.1 - 0.071 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RuvB_N PF05496.12 AFI84143.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 AFI84143.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AFI84143.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 AFI84143.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family HisKA PF00512.25 AFI84144.1 - 1.3e-11 44.3 3.9 1.6e-11 44.0 0.9 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF2649 PF10854.8 AFI84144.1 - 0.02 15.2 0.4 0.085 13.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) HAMP PF00672.25 AFI84144.1 - 0.065 13.6 0.0 0.51 10.8 0.0 2.3 2 0 0 2 2 2 0 HAMP domain MGDG_synth PF06925.11 AFI84144.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF2839 PF10999.8 AFI84144.1 - 0.15 12.4 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) His_kinase PF06580.13 AFI84144.1 - 0.62 10.4 4.1 1.3 9.4 0.3 2.7 3 0 0 3 3 3 0 Histidine kinase Response_reg PF00072.24 AFI84145.1 - 8e-27 93.6 0.1 1.2e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84145.1 - 3.3e-14 52.7 0.0 6.1e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HlyD_3 PF13437.6 AFI84146.1 - 5.5e-11 43.1 0.4 5.1e-09 36.8 0.1 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AFI84146.1 - 2.8e-08 33.3 2.9 6.3e-08 32.1 2.9 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AFI84146.1 - 0.0055 16.5 0.1 0.028 14.2 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like DUF2339 PF10101.9 AFI84146.1 - 0.053 12.1 0.7 0.078 11.6 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) OEP PF02321.18 AFI84146.1 - 0.53 10.1 13.5 3.3 7.5 7.7 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein OEP PF02321.18 AFI84147.1 - 2.3e-38 131.9 42.9 1.6e-20 73.7 19.1 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein MFS_1 PF07690.16 AFI84148.1 - 1e-35 123.3 46.6 1e-35 123.3 46.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AFI84148.1 - 3e-11 42.8 15.1 3e-11 42.8 15.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MS_channel PF00924.18 AFI84150.1 - 5.9e-45 153.3 5.8 8.5e-45 152.8 0.1 2.4 2 1 0 2 2 2 1 Mechanosensitive ion channel DUF92 PF01940.16 AFI84150.1 - 0.044 13.2 0.6 0.071 12.5 0.6 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 TANGO2 PF05742.12 AFI84150.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Transport and Golgi organisation 2 Sulfate_transp PF00916.20 AFI84151.1 - 3.1e-57 194.1 33.2 4.7e-30 104.6 17.0 2.4 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 AFI84151.1 - 2.8e-11 43.1 0.1 5.9e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AFI84151.1 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 AFI84151.1 - 0.0032 17.9 6.9 0.0032 17.9 6.9 4.2 4 1 0 4 4 4 2 Molybdate transporter of MFS superfamily Pho86 PF11124.8 AFI84151.1 - 1.4 8.3 0.0 1.4 8.3 0.0 3.1 3 1 1 4 4 4 0 Inorganic phosphate transporter Pho86 Usp PF00582.26 AFI84152.1 - 3.3e-27 95.7 0.6 5e-10 40.1 0.1 3.3 2 2 1 3 3 3 3 Universal stress protein family Methyltransf_24 PF13578.6 AFI84152.1 - 0.0037 18.3 2.3 1.8 9.6 0.2 3.1 1 1 1 2 2 2 2 Methyltransferase domain YcgR PF07317.12 AFI84152.1 - 0.016 15.1 0.2 0.046 13.6 0.2 1.9 1 1 1 2 2 2 0 Flagellar regulator YcgR zf-dskA_traR PF01258.17 AFI84153.1 - 1.1e-05 25.2 2.0 1.3e-05 25.0 0.4 1.8 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 AFI84153.1 - 0.031 14.3 0.2 0.047 13.7 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon GGDEF PF00990.21 AFI84154.1 - 4e-45 153.4 0.2 9.9e-45 152.2 0.2 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PHY PF00360.20 AFI84154.1 - 3.3e-19 68.9 0.9 7.3e-19 67.8 0.4 1.8 1 1 1 2 2 2 1 Phytochrome region PAS_2 PF08446.11 AFI84154.1 - 6.4e-16 59.0 0.9 2.4e-15 57.1 0.0 2.4 3 0 0 3 3 3 1 PAS fold GAF PF01590.26 AFI84154.1 - 7.8e-09 36.3 2.4 1.4e-08 35.5 0.2 2.4 2 0 0 2 2 2 1 GAF domain GGDEF_2 PF17853.1 AFI84154.1 - 0.0026 18.0 0.2 0.0026 18.0 0.2 3.1 4 0 0 4 4 4 1 GGDEF-like domain FlxA PF14282.6 AFI84154.1 - 0.088 12.8 0.2 0.088 12.8 0.2 2.2 2 0 0 2 2 2 0 FlxA-like protein AbiEi_3 PF11459.8 AFI84155.1 - 2.3e-53 180.1 0.1 3.3e-53 179.7 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system AbiEi_3_N PF17194.4 AFI84155.1 - 4.1e-30 103.7 2.8 7e-30 102.9 2.8 1.4 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin N-terminal domain AbiEii PF08843.11 AFI84156.1 - 2e-44 152.3 0.4 2.4e-44 152.1 0.4 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system GTP_EFTU PF00009.27 AFI84157.1 - 6.2e-50 169.4 0.0 8.9e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 AFI84157.1 - 8e-46 155.1 0.0 1.4e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AFI84157.1 - 1.5e-08 34.9 0.0 3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AFI84157.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AFI84157.1 - 8.9e-05 22.5 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 AFI84157.1 - 0.033 13.6 0.2 0.28 10.6 0.2 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CBS PF00571.28 AFI84158.1 - 1.1e-29 102.6 0.9 3.7e-15 56.1 0.1 2.1 2 0 0 2 2 2 2 CBS domain VAPB_antitox PF02697.14 AFI84158.1 - 0.045 14.5 0.1 0.68 10.8 0.0 2.4 2 1 0 2 2 2 0 Putative antitoxin DUF3579 PF12112.8 AFI84159.1 - 2.6e-33 114.4 0.0 3e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3579) tRNA-synt_1 PF00133.22 AFI84160.1 - 6.2e-222 738.1 0.0 7.5e-222 737.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AFI84160.1 - 4e-28 98.3 0.1 8.8e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AFI84160.1 - 1.2e-23 83.6 0.0 1.8e-11 43.4 0.0 3.5 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AFI84160.1 - 3.7e-10 39.6 0.0 6.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AFI84160.1 - 1.6e-08 34.3 0.0 9.5e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AFI84160.1 - 1.1e-06 27.8 0.0 4.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.14 AFI84160.1 - 7.7e-05 22.5 4.8 7.7e-05 22.5 4.8 2.8 3 0 0 3 3 3 1 Zinc finger found in FPG and IleRS Peptidase_A8 PF01252.18 AFI84161.1 - 1.9e-40 138.4 10.8 2.1e-40 138.2 10.8 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II MscL PF01741.18 AFI84161.1 - 0.018 15.3 1.0 0.038 14.3 1.0 1.6 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF4149 PF13664.6 AFI84161.1 - 0.18 12.1 4.6 0.22 11.9 2.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF1772 PF08592.11 AFI84161.1 - 1.6 9.0 7.6 2.5 8.4 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Aminotran_1_2 PF00155.21 AFI84162.1 - 1.9e-60 205.0 0.0 2.3e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AFI84162.1 - 2e-07 30.3 0.4 2.2e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AFI84162.1 - 0.0019 17.6 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 AFI84162.1 - 0.0034 16.1 0.0 0.0054 15.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 AFI84162.1 - 0.0034 16.0 0.1 0.0084 14.7 0.1 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme PDH PF02153.17 AFI84163.1 - 1.2e-78 263.7 0.0 1.4e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 AFI84163.1 - 1.8e-14 54.2 0.4 6.3e-14 52.4 0.8 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AFI84163.1 - 2.2e-13 50.6 1.3 4.7e-13 49.5 0.4 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 AFI84163.1 - 1.2e-07 31.4 0.3 2.4e-07 30.5 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 AFI84163.1 - 1.8e-07 31.0 0.3 3.6e-07 30.0 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 AFI84163.1 - 1.8e-06 27.4 0.4 1.1e-05 24.8 0.1 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AFI84163.1 - 9.5e-06 25.7 2.4 0.00069 19.6 1.8 2.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 AFI84163.1 - 4.6e-05 23.3 1.9 0.0001 22.2 1.9 1.5 1 0 0 1 1 1 1 Rossmann-like domain GFO_IDH_MocA PF01408.22 AFI84163.1 - 0.00025 21.8 0.7 0.0011 19.8 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 AFI84163.1 - 0.00097 19.6 0.6 0.0038 17.6 0.3 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AFI84163.1 - 0.0011 18.8 3.3 0.75 9.6 0.0 2.5 2 1 1 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 AFI84163.1 - 0.0036 17.8 0.7 0.039 14.5 0.1 2.3 2 1 0 2 2 2 1 CoA binding domain NAD_binding_10 PF13460.6 AFI84163.1 - 0.02 14.8 0.6 0.02 14.8 0.6 1.8 2 0 0 2 2 2 0 NAD(P)H-binding OCD_Mu_crystall PF02423.15 AFI84163.1 - 0.043 12.8 0.8 0.13 11.2 0.3 1.8 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family ADH_zinc_N PF00107.26 AFI84163.1 - 0.09 12.8 1.2 0.52 10.3 0.6 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 AFI84163.1 - 0.097 12.9 0.8 0.29 11.4 0.3 2.1 2 0 0 2 2 2 0 TrkA-N domain PGK PF00162.19 AFI84163.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoglycerate kinase Shikimate_DH PF01488.20 AFI84163.1 - 0.12 12.4 0.3 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 AFI84163.1 - 0.19 11.8 2.4 3.3 7.8 0.7 2.3 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain EPSP_synthase PF00275.20 AFI84164.1 - 4.9e-120 401.0 0.2 5.9e-120 400.8 0.2 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Cytidylate_kin PF02224.18 AFI84165.1 - 5.1e-77 258.4 0.1 5.7e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AFI84165.1 - 4.4e-09 36.7 0.1 1.8e-08 34.7 0.1 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AFI84165.1 - 5.3e-06 27.0 0.0 8.1e-05 23.2 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AFI84165.1 - 1.8e-05 25.2 0.2 0.00037 20.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AFI84165.1 - 0.00011 22.4 0.1 0.00032 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 AFI84165.1 - 0.0019 18.3 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase SKI PF01202.22 AFI84165.1 - 0.011 15.9 0.1 0.028 14.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate kinase NACHT PF05729.12 AFI84165.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain dNK PF01712.19 AFI84165.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_5 PF07728.14 AFI84165.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AFI84165.1 - 0.028 14.7 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AFI84165.1 - 0.029 14.3 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.6 AFI84165.1 - 0.059 13.8 1.2 0.19 12.1 1.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_2 PF03668.15 AFI84165.1 - 0.074 12.3 0.3 1 8.6 0.0 2.1 1 1 0 2 2 2 0 P-loop ATPase protein family NB-ARC PF00931.22 AFI84165.1 - 0.077 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 AFI84165.1 - 0.086 13.4 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 AFI84165.1 - 0.11 12.7 0.1 0.32 11.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 AFI84165.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AFI84165.1 - 0.23 11.9 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase S1 PF00575.23 AFI84166.1 - 8.5e-96 314.4 28.2 6.3e-23 80.9 0.7 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 AFI84166.1 - 2.4e-09 37.9 6.4 0.3 11.8 0.1 6.2 2 2 4 6 6 6 3 Penicillin-binding protein OB-like domain CsrA PF02599.16 AFI84166.1 - 2.9e-05 23.9 2.1 0.85 9.6 0.0 4.3 4 0 0 4 4 4 2 Global regulator protein family S1_2 PF13509.6 AFI84166.1 - 0.00023 21.1 7.6 1.2 9.2 0.3 5.8 5 3 0 5 5 5 2 S1 domain DUF4354 PF14263.6 AFI84166.1 - 0.044 13.6 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4354) DUF1344 PF07076.11 AFI84166.1 - 0.046 13.6 2.5 11 6.0 0.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1344) DUF2442 PF10387.9 AFI84166.1 - 0.057 13.7 0.0 13 6.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Ribosomal_L19 PF01245.20 AFI84166.1 - 0.058 13.3 0.8 28 4.7 0.0 4.1 4 0 0 4 4 4 0 Ribosomal protein L19 OB_aCoA_assoc PF01796.17 AFI84166.1 - 1.5 8.9 5.4 0.71 9.9 0.2 3.1 4 0 0 4 4 4 0 DUF35 OB-fold domain, acyl-CoA-associated BPL_C PF02237.17 AFI84166.1 - 2.2 8.3 11.6 15 5.5 0.0 5.3 5 1 1 6 6 6 0 Biotin protein ligase C terminal domain Bac_DNA_binding PF00216.21 AFI84167.1 - 6.5e-30 103.2 0.0 7.2e-30 103.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AFI84167.1 - 1.2e-06 28.6 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AFI84167.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AFI84167.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AFI84167.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 DUF498 PF04430.14 AFI84168.1 - 1.3e-15 57.4 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) COX1 PF00115.20 AFI84169.1 - 4.7e-99 332.2 63.5 4.7e-99 332.2 63.5 1.3 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I FixO PF02433.15 AFI84170.1 - 5.4e-84 281.0 0.5 1.8e-79 266.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_C PF00034.21 AFI84170.1 - 0.018 16.2 0.3 0.095 13.9 0.3 2.0 1 1 0 1 1 1 0 Cytochrome c FixQ PF05545.11 AFI84171.1 - 7.8e-12 45.0 0.0 9.5e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ DUF2615 PF11027.8 AFI84171.1 - 0.041 14.0 0.0 0.042 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) YajC PF02699.15 AFI84171.1 - 0.052 13.4 0.5 0.08 12.8 0.5 1.3 1 1 0 1 1 1 0 Preprotein translocase subunit Orf78 PF06024.12 AFI84171.1 - 0.075 13.3 0.2 0.1 12.9 0.1 1.3 1 1 0 1 1 1 0 Orf78 (ac78) Cytochrome_CBB3 PF13442.6 AFI84172.1 - 3e-19 69.1 0.4 6.2e-09 36.0 0.0 2.8 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III FixP_N PF14715.6 AFI84172.1 - 1.3e-18 66.4 2.4 2.8e-18 65.4 2.4 1.5 1 0 0 1 1 1 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrom_C PF00034.21 AFI84172.1 - 6.4e-17 62.5 0.1 1.6e-08 35.6 0.0 3.3 2 1 0 2 2 2 2 Cytochrome c Cytochrome_C7 PF14522.6 AFI84172.1 - 0.037 14.0 0.0 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF21 PF01595.20 AFI84172.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Syndecan PF01034.20 AFI84173.1 - 0.0044 16.9 1.5 0.0048 16.8 1.5 1.0 1 0 0 1 1 1 1 Syndecan domain DUF3302 PF11742.8 AFI84173.1 - 0.016 15.3 0.7 0.018 15.1 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Insulin_TMD PF17870.1 AFI84173.1 - 0.15 12.1 5.1 0.18 11.9 5.1 1.1 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FixH PF05751.11 AFI84174.1 - 1.1e-25 90.4 0.0 1.3e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 FixH YtkA PF13115.6 AFI84174.1 - 0.0089 16.6 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 YtkA-like DUF3796 PF12676.7 AFI84174.1 - 0.14 12.6 0.5 0.25 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF2142 PF09913.9 AFI84174.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) FixS PF03597.15 AFI84175.1 - 1.2e-21 76.1 0.6 1.7e-21 75.6 0.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type MSP1a PF11670.8 AFI84175.1 - 0.068 12.5 0.0 0.08 12.2 0.0 1.0 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) FixQ PF05545.11 AFI84175.1 - 0.097 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Peripla_BP_6 PF13458.6 AFI84176.1 - 5.7e-48 164.3 0.1 6.5e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AFI84176.1 - 1.1e-10 41.1 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AFI84176.1 - 5.4e-07 28.9 0.2 3.1e-06 26.4 0.1 2.0 2 1 0 2 2 2 1 Periplasmic binding protein domain EAL PF00563.20 AFI84177.1 - 4.8e-71 239.1 0.2 1.9e-70 237.1 0.2 2.1 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI84177.1 - 5.9e-52 175.7 3.1 2.6e-51 173.6 0.0 3.0 3 0 0 3 3 3 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AFI84177.1 - 1.5e-17 63.6 0.4 4.2e-09 36.4 0.0 3.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AFI84177.1 - 1.5e-17 63.7 0.0 8.9e-08 32.3 0.0 3.7 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 AFI84177.1 - 1.2e-09 38.0 0.0 0.0005 20.0 0.0 3.2 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AFI84177.1 - 2.8e-07 30.8 0.1 0.0081 16.4 0.0 3.3 3 0 0 3 3 3 2 PAS fold HAMP PF00672.25 AFI84177.1 - 6.6e-07 29.6 0.5 3.4e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 HAMP domain PAS_3 PF08447.12 AFI84177.1 - 0.001 19.3 0.0 0.017 15.4 0.0 2.7 2 0 0 2 2 2 1 PAS fold CrgA PF06781.12 AFI84177.1 - 0.066 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Cell division protein CrgA DUF3328 PF11807.8 AFI84177.1 - 0.37 10.5 2.8 0.53 10.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Phage_holin_1 PF04531.13 AFI84177.1 - 2 9.0 8.5 8.2 7.0 1.5 3.9 5 0 0 5 5 3 0 Bacteriophage holin Wzz PF02706.15 AFI84177.1 - 3.2 8.1 6.0 5.9 7.3 0.2 3.4 3 0 0 3 3 3 0 Chain length determinant protein Tyr_Deacylase PF02580.16 AFI84179.1 - 2.9e-50 170.5 0.0 3.6e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Abhydrolase_1 PF00561.20 AFI84180.1 - 2.5e-30 106.0 0.2 4.1e-30 105.3 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AFI84180.1 - 6.7e-17 61.5 0.0 1.6e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AFI84180.1 - 9.5e-12 46.0 1.4 1.4e-11 45.5 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AFI84180.1 - 0.0031 17.2 0.6 0.0055 16.3 0.6 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 AFI84180.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ndr PF03096.14 AFI84180.1 - 0.079 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family LIP PF03583.14 AFI84180.1 - 0.13 11.6 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 Secretory lipase ATP-grasp_2 PF08442.10 AFI84181.1 - 1.2e-75 253.6 0.1 1.8e-75 253.0 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AFI84181.1 - 1.6e-25 89.7 1.5 2.6e-25 89.0 1.5 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AFI84181.1 - 2.3e-16 60.0 0.2 3.9e-16 59.2 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AFI84181.1 - 0.001 18.9 0.1 0.002 18.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 AFI84181.1 - 0.024 14.4 0.2 0.052 13.3 0.2 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp PF02222.22 AFI84181.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain TLC PF03219.14 AFI84181.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 TLC ATP/ADP transporter CoA_binding PF02629.19 AFI84182.1 - 2.5e-31 108.2 1.4 2.5e-31 108.2 1.4 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AFI84182.1 - 9.8e-19 67.7 0.9 1.7e-18 66.9 0.9 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AFI84182.1 - 4e-10 39.6 0.3 1.9e-09 37.4 0.1 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AFI84182.1 - 0.0031 18.0 0.0 0.0081 16.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain NAD_synthase PF02540.17 AFI84183.1 - 4.8e-75 251.8 0.0 8.9e-75 250.9 0.0 1.4 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 AFI84183.1 - 1.1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_Me_trans PF03054.16 AFI84183.1 - 0.00094 18.1 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 AFI84183.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC P-II PF00543.22 AFI84184.1 - 2e-44 150.4 0.4 2.2e-44 150.2 0.5 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AFI84184.1 - 0.00086 19.4 0.0 0.001 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) YfiO PF13525.6 AFI84185.1 - 4.7e-65 219.1 11.8 6.8e-65 218.6 11.8 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 AFI84185.1 - 5.6e-44 149.8 7.6 6.4e-44 149.6 3.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AFI84185.1 - 7.7e-10 38.8 11.9 0.003 18.1 0.3 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 AFI84185.1 - 5.6e-09 36.5 17.1 7.4e-06 26.5 4.0 3.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AFI84185.1 - 0.0038 17.7 6.5 0.0099 16.4 1.4 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 AFI84185.1 - 0.004 16.9 0.3 0.009 15.7 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 AFI84185.1 - 0.0042 17.8 9.2 4.4 8.4 0.4 4.8 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 AFI84185.1 - 0.0067 16.4 1.7 0.059 13.4 0.6 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat LPAM_1 PF08139.12 AFI84185.1 - 0.007 16.8 1.3 0.015 15.7 1.3 1.6 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site ANAPC3 PF12895.7 AFI84185.1 - 0.012 15.9 7.9 0.016 15.4 0.9 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 AFI84185.1 - 0.037 14.0 1.9 0.09 12.8 0.4 2.1 2 0 0 2 2 2 0 Putative TPR-like repeat BTAD PF03704.17 AFI84185.1 - 0.044 14.2 2.5 0.15 12.5 0.4 2.5 1 1 2 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 AFI84185.1 - 0.076 13.2 5.2 0.22 11.7 0.1 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84185.1 - 0.096 12.9 10.4 0.4 10.9 0.5 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 AFI84185.1 - 0.11 12.8 5.9 1.4 9.3 0.4 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84185.1 - 4.8 7.2 8.5 3.9 7.5 1.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YkuD PF03734.14 AFI84186.1 - 7.4e-19 68.6 0.0 1.3e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain SPOR PF05036.13 AFI84186.1 - 0.028 14.8 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Sporulation related domain Alanine_zipper PF11839.8 AFI84187.1 - 1.3e-17 63.9 19.5 1.3e-17 63.9 19.5 1.6 2 0 0 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein RRF PF01765.19 AFI84187.1 - 0.068 13.1 1.0 0.077 12.9 1.0 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Inositol_P PF00459.25 AFI84188.1 - 2.3e-69 233.9 0.0 2.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family GTP_EFTU PF00009.27 AFI84189.1 - 4.2e-54 183.0 0.0 6.5e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AFI84189.1 - 2.2e-22 78.9 0.0 6.9e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AFI84189.1 - 2.5e-11 43.8 1.7 4.3e-11 43.1 0.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AFI84189.1 - 1.4e-06 28.4 0.0 3.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI84189.1 - 0.0015 18.1 0.0 0.24 10.9 0.0 3.5 3 1 0 3 3 3 1 Ferrous iron transport protein B Septin PF00735.18 AFI84189.1 - 0.0045 16.3 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Septin EFG_II PF14492.6 AFI84189.1 - 0.01 15.9 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.23 AFI84189.1 - 0.091 12.8 0.0 1.3 9.0 0.0 2.0 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 AFI84189.1 - 0.15 11.5 0.0 0.41 10.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit VATC PF18716.1 AFI84190.1 - 0.0058 16.5 0.7 0.0069 16.2 0.7 1.2 1 0 0 1 1 1 1 Vms1-associating treble clef domain Metallothio_Pro PF02069.16 AFI84190.1 - 0.0075 16.5 0.2 0.0096 16.1 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic metallothionein zf-RING_7 PF02591.15 AFI84190.1 - 0.013 15.7 0.6 0.022 14.9 0.2 1.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain FeoB_associated PF12669.7 AFI84190.1 - 0.09 13.2 1.1 0.18 12.2 1.1 1.5 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein NicO PF03824.16 AFI84190.1 - 0.13 11.6 0.1 0.13 11.6 0.1 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Cas9_PI2 PF18070.1 AFI84190.1 - 0.34 11.7 3.5 0.63 10.8 1.5 2.0 1 1 1 2 2 2 0 CRISPR-Cas9 PI domain HATPase_c PF02518.26 AFI84191.1 - 2.1e-20 73.3 0.0 4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84191.1 - 3.4e-14 52.6 1.6 3.4e-14 52.6 1.6 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AFI84191.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AFI84191.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AFI84191.1 - 0.00046 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI84191.1 - 0.0047 16.9 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AFI84191.1 - 0.012 15.5 0.0 0.044 13.7 0.0 1.9 3 0 0 3 3 3 0 GHKL domain NifQ PF04891.12 AFI84191.1 - 0.12 12.8 0.5 23 5.3 0.0 3.5 2 1 2 4 4 4 0 NifQ PAS_4 PF08448.10 AFI84191.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Sigma54_activat PF00158.26 AFI84192.1 - 6.5e-67 224.4 0.1 8.9e-67 224.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AFI84192.1 - 1.3e-26 92.9 0.1 3.2e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AFI84192.1 - 1.2e-25 90.2 0.0 4e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AFI84192.1 - 3.9e-16 58.5 3.2 9.5e-16 57.3 3.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI84192.1 - 0.0026 17.8 0.0 0.0079 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AFI84192.1 - 0.0081 15.6 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HTH_50 PF18024.1 AFI84192.1 - 0.076 12.6 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain GCV_T PF01571.21 AFI84193.1 - 2.1e-11 43.7 0.0 4.3e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain Cpta_toxin PF07254.12 AFI84194.1 - 0.0013 18.7 1.4 0.0024 17.8 1.4 1.4 1 1 0 1 1 1 1 Membrane-bound toxin component of toxin-antitoxin system FAD_binding_2 PF00890.24 AFI84195.1 - 1.4e-96 324.1 0.3 1.9e-96 323.7 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AFI84195.1 - 1.4e-15 57.5 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AFI84195.1 - 3e-06 26.7 0.4 0.0084 15.4 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AFI84195.1 - 3.2e-05 23.7 0.1 5.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AFI84195.1 - 0.07 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 AFI84195.1 - 0.14 11.3 0.9 0.37 10.0 0.1 2.1 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.6 AFI84195.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sigma70_r4_2 PF08281.12 AFI84196.1 - 2.6e-19 68.6 0.1 5.7e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI84196.1 - 1.7e-17 62.9 0.1 3.2e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AFI84196.1 - 1.7e-11 44.3 0.1 4.7e-11 42.9 0.1 1.7 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AFI84196.1 - 4.3e-11 42.1 0.0 7.1e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_16 PF12645.7 AFI84196.1 - 0.00026 21.0 0.1 0.00061 19.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI84196.1 - 0.00096 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_40 PF14493.6 AFI84196.1 - 0.006 17.0 0.7 0.53 10.8 0.0 2.7 2 1 1 3 3 3 1 Helix-turn-helix domain Phage_antitermQ PF06530.12 AFI84196.1 - 0.015 15.2 0.5 0.72 9.8 0.1 2.7 3 0 0 3 3 3 0 Phage antitermination protein Q GerE PF00196.19 AFI84196.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_20 PF12840.7 AFI84196.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain RseA_N PF03872.13 AFI84197.1 - 1.2e-10 41.7 0.0 2.1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Anti sigma-E protein RseA, N-terminal domain zf-HC2 PF13490.6 AFI84197.1 - 0.093 13.0 0.3 0.68 10.2 0.1 2.3 2 0 0 2 2 2 0 Putative zinc-finger DUF1439 PF07273.12 AFI84197.1 - 0.095 12.5 0.0 0.47 10.3 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1439) MucB_RseB PF03888.14 AFI84198.1 - 3.8e-61 205.7 0.0 5.1e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 MucB/RseB N-terminal domain MucB_RseB_C PF17188.4 AFI84198.1 - 1.2e-25 89.5 0.1 2.1e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 MucB/RseB C-terminal domain LolA_like PF17131.4 AFI84198.1 - 0.00014 21.6 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein-sorting protein DUF1571 PF07608.11 AFI84198.1 - 0.086 12.3 0.3 0.24 10.8 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1571) RseC_MucC PF04246.12 AFI84199.1 - 2.8e-30 104.9 0.1 3.1e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC YniB PF14002.6 AFI84199.1 - 0.025 14.4 0.9 0.23 11.2 0.1 2.0 1 1 1 2 2 2 0 YniB-like protein Trypsin_2 PF13365.6 AFI84200.1 - 1.9e-33 116.5 0.2 3e-33 115.8 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AFI84200.1 - 2.6e-25 88.6 1.3 8.7e-14 51.6 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 AFI84200.1 - 2.2e-20 72.3 1.8 1.1e-09 38.0 0.3 2.9 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AFI84200.1 - 1.8e-15 57.1 0.9 6.9e-07 29.5 0.2 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 AFI84200.1 - 4.8e-15 56.0 0.0 1.3e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 AFI84200.1 - 4e-05 22.5 0.3 0.047 12.3 0.2 2.1 2 0 0 2 2 2 2 Peptidase S46 Tricorn_PDZ PF14685.6 AFI84200.1 - 0.0023 17.8 0.4 2.3 8.3 0.0 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 AFI84200.1 - 0.0081 16.2 0.0 0.049 13.6 0.0 2.2 2 0 0 2 2 2 1 PDZ-like domain Peptidase_S29 PF02907.15 AFI84200.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Response_reg PF00072.24 AFI84202.1 - 9e-26 90.2 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84202.1 - 2.1e-20 72.6 0.1 4.6e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Glyco_transf_25 PF01755.17 AFI84202.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) HK_sensor PF16750.5 AFI84203.1 - 4.8e-39 133.1 0.3 3.1e-38 130.5 0.1 2.1 2 0 0 2 2 2 1 Sensor domain of 2-component histidine kinase HATPase_c PF02518.26 AFI84203.1 - 8.7e-20 71.3 0.0 2.2e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AFI84203.1 - 2.2e-11 44.0 0.0 4.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AFI84203.1 - 3.2e-10 39.9 1.7 3.2e-10 39.9 1.7 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AFI84203.1 - 0.0068 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4446 PF14584.6 AFI84203.1 - 0.0094 16.0 0.4 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) TonB_dep_Rec PF00593.24 AFI84204.1 - 9.1e-45 154.4 27.6 1.4e-44 153.7 27.6 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI84204.1 - 2.6e-16 60.1 0.7 5.9e-16 59.0 0.7 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AFI84204.1 - 6.9e-05 22.0 3.0 0.0089 15.1 0.0 3.0 2 1 1 3 3 3 2 Outer membrane protein beta-barrel family BBP2_2 PF10082.9 AFI84204.1 - 0.014 14.3 0.5 1.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Putative beta-barrel porin 2 OMP_b-brl PF13505.6 AFI84204.1 - 0.026 14.6 12.0 0.044 13.9 1.1 3.6 3 1 1 4 4 4 0 Outer membrane protein beta-barrel domain MatE PF01554.18 AFI84205.1 - 2.6e-37 128.0 46.1 1.2e-21 77.0 20.4 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 AFI84205.1 - 9.9e-08 32.2 6.9 9.9e-08 32.2 6.9 5.0 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain GTP_EFTU PF00009.27 AFI84206.1 - 1.3e-50 171.7 0.0 2.1e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AFI84206.1 - 1.5e-50 169.8 3.5 2.9e-50 168.9 3.5 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AFI84206.1 - 2.7e-19 69.0 0.0 6.1e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AFI84206.1 - 8.9e-09 35.6 1.6 2.4e-08 34.2 1.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 AFI84206.1 - 8e-05 22.3 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 AFI84206.1 - 0.00013 22.0 0.0 0.00053 20.0 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AFI84206.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 AFI84206.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 AFI84206.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 AFI84206.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Peptidase_S24 PF00717.23 AFI84207.1 - 3.8e-23 81.2 0.7 7.1e-23 80.4 0.2 1.7 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 AFI84207.1 - 5.8e-11 42.3 0.0 6.1e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF4845 PF16137.5 AFI84208.1 - 3.9e-22 78.9 0.3 4.7e-22 78.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4845) N_methyl PF07963.12 AFI84208.1 - 9.2e-06 25.0 0.7 1.5e-05 24.4 0.7 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF3139 PF11337.8 AFI84208.1 - 0.095 13.4 1.3 0.14 12.8 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) Ribonucleas_3_3 PF14622.6 AFI84209.1 - 2.9e-33 114.8 0.0 4.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AFI84209.1 - 1.8e-22 79.9 0.0 3.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 AFI84209.1 - 3.3e-06 27.7 0.3 8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif MMR_HSR1 PF01926.23 AFI84210.1 - 2.2e-26 92.2 0.1 4.7e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 AFI84210.1 - 3.8e-21 74.7 0.2 2.5e-20 72.1 0.0 2.3 2 0 0 2 2 2 1 KH domain FeoB_N PF02421.18 AFI84210.1 - 3.5e-16 59.1 0.0 5.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 AFI84210.1 - 3.1e-10 39.8 0.0 4.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 AFI84210.1 - 3.5e-10 39.7 0.1 3.2e-07 30.1 0.1 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AFI84210.1 - 2.1e-09 37.5 2.3 0.0013 18.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AFI84210.1 - 2.7e-08 34.0 0.2 0.00037 20.6 0.1 2.2 1 1 1 2 2 2 2 Dynamin family MMR_HSR1_Xtn PF16897.5 AFI84210.1 - 4.8e-06 26.5 0.1 9.2e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 AFI84210.1 - 4.7e-05 23.2 0.1 0.00027 20.7 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 AFI84210.1 - 0.00018 21.7 0.1 0.00063 19.9 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 AFI84210.1 - 0.0011 18.5 1.5 0.016 14.8 0.4 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Spore_IV_A PF09547.10 AFI84210.1 - 0.0018 17.3 2.4 0.11 11.4 0.2 2.4 2 1 1 3 3 3 2 Stage IV sporulation protein A (spore_IV_A) Ras PF00071.22 AFI84210.1 - 0.0023 17.5 0.1 0.014 15.0 0.1 2.1 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 AFI84210.1 - 0.0042 17.5 0.0 3.5 8.0 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Gtr1_RagA PF04670.12 AFI84210.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 AFI84210.1 - 0.023 15.1 0.2 0.14 12.6 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AFI84210.1 - 0.043 14.1 0.1 0.19 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AFI84210.1 - 0.058 13.2 0.1 1.9 8.2 0.1 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AFI84210.1 - 0.095 13.2 0.0 0.91 10.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter RecO_C PF02565.15 AFI84211.1 - 3e-22 79.1 3.2 6.8e-22 78.0 3.2 1.5 1 1 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 AFI84211.1 - 2.8e-19 68.9 0.0 8.3e-19 67.3 0.0 1.8 2 0 0 2 2 2 1 Recombination protein O N terminal E3_UbLigase_RBR PF18091.1 AFI84211.1 - 0.045 13.9 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain TetR_C_20 PF17925.1 AFI84211.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PdxJ PF03740.13 AFI84212.1 - 1.9e-103 344.6 4.7 2.2e-103 344.4 4.7 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 AFI84212.1 - 4e-05 23.2 1.9 0.00026 20.5 0.9 2.3 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel BKACE PF05853.12 AFI84212.1 - 0.0051 16.1 4.1 0.17 11.1 0.1 2.2 2 0 0 2 2 2 2 beta-keto acid cleavage enzyme DNA_pol3_tau_5 PF12170.8 AFI84212.1 - 0.095 12.8 0.2 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase III tau subunit V interacting with alpha ACPS PF01648.20 AFI84213.1 - 3.9e-19 68.9 0.0 4.4e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PALP PF00291.25 AFI84214.1 - 1.6e-64 218.2 0.1 2.2e-64 217.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pox_RNA_pol PF03293.14 AFI84214.1 - 0.0077 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus DNA-directed RNA polymerase, 18 kD subunit DctA-YdbH PF11739.8 AFI84215.1 - 2.1e-05 24.4 7.4 0.00037 20.3 0.2 4.9 4 3 0 4 4 4 2 Dicarboxylate transport DUF1318 PF07027.12 AFI84216.1 - 3.1e-24 85.2 1.2 5.1e-24 84.5 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) tRNA_U5-meth_tr PF05958.11 AFI84217.1 - 1.4e-28 99.9 0.0 1.1e-27 97.0 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 AFI84217.1 - 4.4e-09 36.3 0.0 9.5e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AFI84217.1 - 1.8e-08 33.8 0.0 3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AFI84217.1 - 1.1e-07 32.5 0.0 7e-07 29.9 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain PCMT PF01135.19 AFI84217.1 - 2.6e-07 30.6 0.0 4.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TRAM PF01938.20 AFI84217.1 - 9.7e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.10 AFI84217.1 - 3.9e-05 23.3 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 AFI84217.1 - 4.8e-05 23.2 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 AFI84217.1 - 0.0001 22.0 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AFI84217.1 - 0.00015 21.4 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AFI84217.1 - 0.0022 17.8 0.0 0.005 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI84217.1 - 0.0041 17.7 0.0 0.014 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AFI84217.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DOT1 PF08123.13 AFI84217.1 - 0.019 14.5 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 PrmA PF06325.13 AFI84217.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 AFI84217.1 - 0.2 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase PEP-CTERM PF07589.11 AFI84218.1 - 0.00028 20.8 1.3 0.00028 20.8 1.3 2.0 2 0 0 2 2 2 1 PEP-CTERM motif VPDSG-CTERM PF18205.1 AFI84218.1 - 0.82 9.5 5.6 0.38 10.6 0.6 2.4 2 0 0 2 2 2 0 VPDSG-CTERM motif DNA_alkylation PF08713.11 AFI84219.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 DNA alkylation repair enzyme HEAT_2 PF13646.6 AFI84219.1 - 0.00063 20.1 0.0 0.54 10.7 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 AFI84219.1 - 0.018 15.3 0.0 13 6.4 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat PPDK_N PF01326.19 AFI84220.1 - 4.7e-117 390.9 0.1 7.1e-117 390.3 0.1 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AFI84220.1 - 3.1e-59 200.5 0.0 4.9e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AFI84220.1 - 1.2e-24 85.8 0.6 2.5e-24 84.8 0.6 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF4470 PF14737.6 AFI84220.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Kinase-PPPase PF03618.14 AFI84221.1 - 3e-74 250.0 0.1 3.5e-74 249.8 0.1 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase Peptidase_S24 PF00717.23 AFI84222.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase S24-like NTP_transferase PF00483.23 AFI84223.1 - 3.5e-24 85.8 0.0 5.3e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI84223.1 - 0.0099 16.2 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain PQQ_3 PF13570.6 AFI84225.1 - 2.8e-66 218.5 0.9 1.8e-09 37.8 0.2 8.1 8 0 0 8 8 8 8 PQQ-like domain PQQ PF01011.21 AFI84225.1 - 4.8e-55 181.0 3.7 5.9e-08 32.3 0.1 8.5 9 0 0 9 9 9 7 PQQ enzyme repeat PQQ_2 PF13360.6 AFI84225.1 - 1.8e-46 158.7 0.3 1e-22 80.9 0.1 3.2 1 1 2 3 3 3 3 PQQ-like domain Tachylectin PF14517.6 AFI84225.1 - 0.0002 21.0 0.4 2.3 7.7 0.0 3.3 1 1 2 3 3 3 2 Tachylectin SUKH-4 PF14435.6 AFI84225.1 - 0.034 14.2 0.0 7.4 6.6 0.0 3.6 1 1 2 3 3 3 0 SUKH-4 immunity protein NTP_transferase PF00483.23 AFI84226.1 - 2.3e-29 102.7 0.0 3.3e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI84226.1 - 8e-05 23.0 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Epimerase PF01370.21 AFI84227.1 - 1.7e-49 168.4 0.0 2.1e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI84227.1 - 6.2e-48 163.9 0.0 9.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AFI84227.1 - 2.3e-19 69.5 0.0 5.3e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AFI84227.1 - 1.1e-11 44.4 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AFI84227.1 - 6.5e-09 35.3 0.0 6.2e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AFI84227.1 - 0.00032 19.9 0.1 0.0011 18.2 0.0 1.9 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 AFI84227.1 - 0.018 15.0 1.9 3 7.7 1.9 2.3 1 1 0 1 1 1 0 KR domain DapB_N PF01113.20 AFI84227.1 - 0.04 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UDPG_MGDP_dh_N PF03721.14 AFI84227.1 - 0.065 12.8 0.3 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 AFI84227.1 - 0.11 12.0 0.5 0.35 10.4 0.1 2.1 2 1 0 2 2 2 0 NmrA-like family MannoseP_isomer PF01050.18 AFI84228.1 - 7.2e-72 240.2 1.1 1.5e-71 239.1 1.1 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transferase PF00483.23 AFI84228.1 - 1.4e-71 241.0 0.1 6.1e-71 238.9 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI84228.1 - 4.7e-11 43.3 0.4 8.1e-08 32.8 0.0 2.9 2 1 1 3 3 3 2 MobA-like NTP transferase domain Cupin_2 PF07883.11 AFI84228.1 - 5.6e-11 42.0 0.1 1.1e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Vps16_N PF04841.13 AFI84228.1 - 0.0035 16.2 0.1 1.7 7.3 0.2 2.1 2 0 0 2 2 2 2 Vps16, N-terminal region Optomotor-blind PF11078.8 AFI84228.1 - 0.062 13.9 0.0 2.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region Bac_transf PF02397.16 AFI84229.1 - 9.5e-61 204.6 0.2 9.5e-61 204.6 0.2 1.6 2 0 0 2 2 2 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AFI84229.1 - 5.7e-33 114.4 0.8 9.6e-33 113.6 0.8 1.4 1 0 0 1 1 1 1 CoA-binding domain DUF4181 PF13789.6 AFI84229.1 - 0.015 15.6 1.8 0.015 15.6 1.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) 2-Hacid_dh_C PF02826.19 AFI84229.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBM_6 PF03422.15 AFI84230.1 - 0.036 14.4 1.0 0.06 13.7 1.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) PEP-CTERM PF07589.11 AFI84230.1 - 1.2 9.3 5.9 0.4 10.8 1.5 2.5 2 0 0 2 2 2 0 PEP-CTERM motif PEP-CTERM PF07589.11 AFI84231.1 - 1.1 9.4 6.0 0.33 11.1 1.4 2.6 2 0 0 2 2 2 0 PEP-CTERM motif CBM_6 PF03422.15 AFI84232.1 - 0.0086 16.4 0.9 0.015 15.6 0.9 1.3 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) PEP-CTERM PF07589.11 AFI84232.1 - 1.4 9.1 6.9 0.23 11.6 2.0 2.2 2 0 0 2 2 2 0 PEP-CTERM motif Poly_export PF02563.16 AFI84233.1 - 3e-22 78.6 0.7 7.7e-22 77.3 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AFI84233.1 - 1.2e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Peptidase_S24 PF00717.23 AFI84233.1 - 0.027 14.4 0.0 1.2 9.1 0.0 2.5 2 1 0 2 2 2 0 Peptidase S24-like BBP2_2 PF10082.9 AFI84234.1 - 4e-11 42.4 20.0 0.0003 19.8 3.6 3.1 2 1 1 3 3 3 3 Putative beta-barrel porin 2 Autotransporter PF03797.19 AFI84234.1 - 3.1e-06 27.0 20.9 7.5e-06 25.8 6.7 3.0 1 1 1 3 3 3 2 Autotransporter beta-domain DUF2490 PF10677.9 AFI84234.1 - 0.00034 20.6 8.3 0.039 13.9 0.4 3.6 2 1 2 4 4 4 3 Protein of unknown function (DUF2490) Bac_surface_Ag PF01103.23 AFI84234.1 - 0.0037 16.8 24.1 0.029 13.9 3.8 2.7 2 1 0 2 2 2 2 Surface antigen OMP_b-brl PF13505.6 AFI84234.1 - 0.009 16.2 11.7 0.009 16.2 11.7 2.9 1 1 1 2 2 2 1 Outer membrane protein beta-barrel domain TonB_dep_Rec PF00593.24 AFI84234.1 - 3.5 7.4 41.1 0.47 10.3 13.0 2.1 1 1 1 2 2 2 0 TonB dependent receptor Wzz PF02706.15 AFI84235.1 - 7.7e-06 26.1 0.4 7.7e-06 26.1 0.4 3.1 2 0 0 2 2 2 1 Chain length determinant protein ABC_tran_CTD PF16326.5 AFI84235.1 - 8.6e-06 25.9 35.4 0.0027 17.9 4.5 5.1 3 1 2 5 5 4 3 ABC transporter C-terminal domain GNVR PF13807.6 AFI84235.1 - 8.1e-05 22.5 0.5 0.0064 16.4 0.0 2.9 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Uds1 PF15456.6 AFI84235.1 - 0.00023 21.3 4.5 0.00023 21.3 4.5 2.9 2 2 0 2 2 2 1 Up-regulated During Septation Tropomyosin_1 PF12718.7 AFI84235.1 - 0.0013 18.9 9.5 0.0013 18.9 9.5 3.5 3 1 2 5 5 4 2 Tropomyosin like GAS PF13851.6 AFI84235.1 - 0.0042 16.4 1.9 0.0042 16.4 1.9 4.0 3 2 1 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 AFI84235.1 - 0.01 15.4 2.5 0.01 15.4 2.5 3.5 1 1 1 3 3 3 0 Intermediate filament protein Occludin_ELL PF07303.13 AFI84235.1 - 0.014 16.1 21.9 1.9 9.3 0.3 4.9 2 2 3 5 5 5 0 Occludin homology domain Tup_N PF08581.10 AFI84235.1 - 0.018 15.3 0.2 0.018 15.3 0.2 4.9 3 2 1 4 4 4 0 Tup N-terminal DUF2157 PF09925.9 AFI84235.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) ATG16 PF08614.11 AFI84235.1 - 0.023 14.9 39.8 0.029 14.6 6.9 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PHB_depo_C PF06850.11 AFI84235.1 - 0.053 13.0 0.1 0.084 12.3 0.1 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus NPV_P10 PF05531.12 AFI84235.1 - 0.063 13.8 7.1 11 6.5 0.6 4.8 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Rep_Org_C PF06926.11 AFI84235.1 - 0.091 13.1 0.9 0.29 11.5 0.6 2.1 2 0 0 2 2 1 0 Putative replisome organiser protein C-terminus DUF1664 PF07889.12 AFI84235.1 - 0.11 12.5 11.9 7 6.7 0.2 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 AFI84235.1 - 0.13 11.6 29.6 1.8 7.9 20.9 3.4 1 1 1 2 2 2 0 Tropomyosin ApoLp-III PF07464.11 AFI84235.1 - 0.21 11.7 18.6 0.13 12.4 1.5 3.9 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Snapin_Pallidin PF14712.6 AFI84235.1 - 0.32 11.4 26.9 0.73 10.3 1.9 4.8 4 1 1 5 5 5 0 Snapin/Pallidin UPF0242 PF06785.11 AFI84235.1 - 0.54 10.3 32.2 0.081 13.0 2.3 3.8 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus HrpB7 PF09486.10 AFI84235.1 - 0.64 10.4 29.9 0.09 13.2 2.5 3.7 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Scaffolding_pro PF11418.8 AFI84235.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.3 4 0 0 4 4 2 0 Phi29 scaffolding protein DUF4407 PF14362.6 AFI84235.1 - 1.5 8.1 33.1 0.16 11.3 13.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 AFI84235.1 - 2.3 8.8 38.2 1.3 9.5 5.3 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF5082 PF16888.5 AFI84235.1 - 2.8 8.3 20.5 2.5 8.4 2.6 4.6 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) ApoO PF09769.9 AFI84235.1 - 3.3 7.7 10.7 27 4.7 0.3 4.5 3 1 0 3 3 3 0 Apolipoprotein O DUF1548 PF07579.11 AFI84235.1 - 4.8 7.5 6.8 0.37 11.1 0.6 2.5 3 0 0 3 3 2 0 Domain of Unknown Function (DUF1548) Spc42p PF11544.8 AFI84235.1 - 5.6 7.0 10.5 12 6.0 0.7 3.6 2 1 1 3 3 2 0 Spindle pole body component Spc42p Spc7 PF08317.11 AFI84235.1 - 6.5 5.5 31.9 0.011 14.6 6.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein KxDL PF10241.9 AFI84235.1 - 7.5 6.9 18.6 38 4.6 0.1 5.0 3 2 0 4 4 4 0 Uncharacterized conserved protein Cep57_CLD_2 PF14197.6 AFI84235.1 - 8.7 6.5 29.9 1 9.5 2.5 5.7 4 1 0 4 4 4 0 Centrosome localisation domain of PPC89 ParA PF10609.9 AFI84236.1 - 1.2e-08 34.8 0.1 1.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 AFI84236.1 - 1.6e-08 34.6 0.1 2.5e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AFI84236.1 - 2.4e-08 34.1 0.0 8.6e-08 32.3 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 AFI84236.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ FTHFS PF01268.19 AFI84236.1 - 0.0072 14.6 0.0 0.0098 14.1 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase AAA_22 PF13401.6 AFI84237.1 - 2.3e-21 76.5 0.1 4.3e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI84237.1 - 2.1e-06 28.2 0.6 0.00016 22.1 0.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AFI84237.1 - 3.1e-06 27.1 0.3 1.6e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AFI84237.1 - 0.00012 21.8 1.4 0.0003 20.4 0.4 2.0 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 AFI84237.1 - 0.00014 21.9 0.4 0.039 13.9 0.2 3.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 AFI84237.1 - 0.00079 19.9 0.0 0.0022 18.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AFI84237.1 - 0.00097 19.7 1.5 0.0019 18.7 0.2 1.9 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AFI84237.1 - 0.0023 17.3 0.1 0.0042 16.4 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 AFI84237.1 - 0.0023 17.7 0.1 0.0048 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AFI84237.1 - 0.0036 17.8 0.4 0.0076 16.8 0.4 1.6 1 1 0 1 1 1 1 ABC transporter NTPase_1 PF03266.15 AFI84237.1 - 0.004 17.1 0.1 0.0082 16.1 0.1 1.5 1 1 0 1 1 1 1 NTPase TsaE PF02367.17 AFI84237.1 - 0.0043 17.0 0.4 0.01 15.9 0.2 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 AFI84237.1 - 0.0056 16.7 0.1 0.015 15.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI84237.1 - 0.0091 15.1 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 AFI84237.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 AFI84237.1 - 0.012 15.6 1.3 0.24 11.3 1.3 2.2 1 1 0 1 1 1 0 NACHT domain MobB PF03205.14 AFI84237.1 - 0.013 15.4 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 AFI84237.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 AFI84237.1 - 0.038 14.3 3.5 0.78 10.1 3.5 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AFI84237.1 - 0.051 13.7 0.2 0.14 12.3 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 AFI84237.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AFI84237.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 AFI84237.1 - 0.089 12.3 0.7 2.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Helicase_RecD PF05127.14 AFI84237.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_33 PF13671.6 AFI84237.1 - 0.15 12.2 0.0 0.85 9.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 AFI84237.1 - 0.16 11.7 0.3 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 AFI84237.1 - 0.19 11.1 4.1 0.79 9.1 0.1 2.5 2 1 1 3 3 3 0 PhoH-like protein AAA_18 PF13238.6 AFI84237.1 - 0.3 11.7 2.6 0.39 11.3 0.4 2.2 2 1 0 2 2 2 0 AAA domain Peroxin-22 PF12827.7 AFI84238.1 - 0.082 12.8 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Nucleotid_trans PF03407.16 AFI84240.1 - 2.5e-05 24.4 1.2 6.8e-05 22.9 1.2 1.7 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glycos_transf_2 PF00535.26 AFI84241.1 - 4.8e-35 120.9 0.0 7.9e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AFI84241.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AFI84241.1 - 2.1e-14 54.0 0.0 3.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AFI84241.1 - 0.012 16.1 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 PP1 PF07430.11 AFI84241.1 - 0.073 13.1 0.2 2.5 8.2 0.0 2.4 1 1 1 2 2 2 0 Phloem filament protein PP1 cystatin-like domain Polysacc_synt_3 PF13440.6 AFI84242.1 - 9e-47 159.7 15.7 9e-47 159.7 15.7 2.4 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 AFI84242.1 - 7.5e-26 91.1 23.4 7.5e-26 91.1 23.4 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Glyco_trans_1_4 PF13692.6 AFI84243.1 - 9e-18 65.0 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AFI84243.1 - 5.5e-16 58.6 0.0 3.3e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI84243.1 - 0.00011 22.6 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 MGDG_synth PF06925.11 AFI84243.1 - 0.12 12.4 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Epimerase PF01370.21 AFI84244.1 - 2.9e-54 184.1 0.0 3.8e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI84244.1 - 1.6e-44 152.7 0.0 5.8e-44 150.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AFI84244.1 - 3.7e-21 75.4 0.0 4.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AFI84244.1 - 2.7e-19 69.8 0.0 4.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AFI84244.1 - 1.4e-11 44.1 0.0 2.2e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 AFI84244.1 - 8.9e-11 41.8 0.0 8.3e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 AFI84244.1 - 5.7e-10 38.8 0.0 7.1e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AFI84244.1 - 2.3e-05 23.7 0.2 0.017 14.3 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein F420_oxidored PF03807.17 AFI84244.1 - 7.9e-05 23.2 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AFI84244.1 - 0.00048 20.3 0.0 0.00082 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 AFI84244.1 - 0.0011 18.5 0.3 0.0064 16.0 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 AFI84244.1 - 0.01 16.1 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 AFI84244.1 - 0.011 16.0 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 AFI84244.1 - 0.029 14.9 0.5 0.076 13.6 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AFI84244.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AFI84244.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 AFI84244.1 - 0.14 11.5 0.2 0.25 10.6 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Wzy_C PF04932.15 AFI84245.1 - 0.00047 19.8 0.0 0.00047 19.8 0.0 3.4 2 2 0 2 2 2 1 O-Antigen ligase Leader_Erm PF08253.11 AFI84246.1 - 0.0063 16.6 0.4 0.028 14.6 0.4 2.1 1 0 0 1 1 1 1 Erm Leader peptide Glycos_transf_2 PF00535.26 AFI84247.1 - 4.5e-16 59.1 0.1 9.8e-16 58.0 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AFI84247.1 - 1.1e-13 51.7 0.0 1.7e-13 51.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AFI84247.1 - 4.4e-06 26.7 0.3 1.1e-05 25.4 0.1 1.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 AFI84247.1 - 7.4e-05 22.4 0.1 0.00017 21.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 AFI84247.1 - 0.0038 16.9 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF4347 PF14252.6 AFI84247.1 - 0.044 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) TEX33 PF15400.6 AFI84247.1 - 0.095 13.2 0.0 0.72 10.4 0.0 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family Sulfotransfer_1 PF00685.27 AFI84248.1 - 4.4e-19 69.0 0.2 1.6e-18 67.1 0.2 1.8 1 1 1 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 AFI84248.1 - 3.1e-16 60.4 0.4 1.2e-11 45.4 0.2 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 AFI84248.1 - 0.00092 19.2 1.6 0.0015 18.5 1.6 1.4 1 1 0 1 1 1 1 Sulfotransferase family Hexapep PF00132.24 AFI84249.1 - 2.8e-06 26.8 14.5 5e-05 22.9 6.7 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AFI84249.1 - 0.00015 21.4 10.1 0.02 14.6 0.3 3.3 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.26 AFI84250.1 - 1.4e-15 57.5 0.0 2.9e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AFI84250.1 - 3.2e-06 27.2 1.0 7.4e-06 26.0 1.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 AFI84250.1 - 0.0002 21.0 0.0 0.00055 19.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AFI84250.1 - 0.00089 19.2 0.1 0.0075 16.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AFI84250.1 - 0.0044 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 AFI84250.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glyco_transf_34 PF05637.12 AFI84250.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family PMT_2 PF13231.6 AFI84251.1 - 9.2e-11 42.2 24.8 9.2e-11 42.2 24.8 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2198 PF09964.9 AFI84251.1 - 1.3 9.2 10.5 0.25 11.4 2.2 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) UbiA PF01040.18 AFI84252.1 - 1.9e-22 79.8 20.0 3e-22 79.1 20.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HAD PF12710.7 AFI84252.1 - 1.4e-06 28.8 0.7 3.7e-05 24.2 0.7 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI84252.1 - 0.043 14.1 0.4 0.98 9.7 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 AFI84252.1 - 0.063 13.1 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Multi_Drug_Res PF00893.19 AFI84253.1 - 5.2e-10 39.9 7.5 7.2e-10 39.4 7.5 1.2 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 AFI84253.1 - 5.9e-10 39.4 15.0 1.3e-09 38.3 15.0 1.6 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 AFI84253.1 - 0.00036 20.6 2.2 0.00036 20.6 2.2 1.4 1 1 0 1 1 1 1 Putative transmembrane family 234 DUF202 PF02656.15 AFI84253.1 - 0.37 11.3 13.0 0.96 9.9 1.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) NdhL PF10716.9 AFI84253.1 - 1 9.3 7.2 0.74 9.8 5.0 1.9 1 1 1 2 2 2 0 NADH dehydrogenase transmembrane subunit Glycos_transf_2 PF00535.26 AFI84254.1 - 3.5e-14 53.0 0.0 9.2e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AFI84254.1 - 0.0001 22.3 0.0 0.0012 18.8 0.0 2.0 1 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AFI84254.1 - 0.0054 17.2 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AFI84254.1 - 0.012 15.1 0.2 5 6.6 0.0 2.8 2 1 1 3 3 3 0 Glycosyl transferase family 21 EFhand_Ca_insen PF08726.10 AFI84254.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Glycos_transf_1 PF00534.20 AFI84255.1 - 5e-30 104.3 0.1 1.3e-29 102.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI84255.1 - 4.8e-28 98.3 0.0 1e-27 97.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI84255.1 - 3.7e-06 27.0 0.1 2.3e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AFI84255.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Asn_synthase PF00733.21 AFI84256.1 - 3.2e-71 240.9 0.0 4e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AFI84256.1 - 1e-43 148.2 0.0 1.8e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AFI84256.1 - 4.7e-38 130.4 0.0 1.1e-37 129.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 AFI84256.1 - 8.1e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 AFI84256.1 - 8.1e-05 21.8 0.1 0.00014 21.0 0.1 1.4 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 AFI84256.1 - 0.011 14.6 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF3700 PF12481.8 AFI84256.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein Poly_export PF02563.16 AFI84257.1 - 4.3e-31 107.0 0.5 4.3e-14 52.5 0.1 2.8 2 1 1 3 3 3 2 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AFI84257.1 - 6.3e-06 26.0 0.3 1.3e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 SLBB domain Tautomerase PF01361.21 AFI84257.1 - 0.054 13.4 0.3 5.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme Gal-bind_lectin PF00337.22 AFI84257.1 - 0.055 13.0 0.1 3.7 7.1 0.0 2.6 3 0 0 3 3 3 0 Galactoside-binding lectin GNVR PF13807.6 AFI84258.1 - 2.8e-07 30.4 0.1 8.1e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 AFI84258.1 - 1.1e-06 28.9 0.1 3.3e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 Chain length determinant protein SMP_2 PF10144.9 AFI84258.1 - 0.0077 15.9 0.8 0.02 14.5 0.8 1.7 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin Vac14_Fab1_bd PF12755.7 AFI84258.1 - 0.045 14.3 1.4 0.061 13.9 0.2 1.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region ATG16 PF08614.11 AFI84258.1 - 0.047 13.9 8.7 0.082 13.1 8.7 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc24 PF08286.11 AFI84258.1 - 6.6 7.0 7.4 0.67 10.2 0.7 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CbiA PF01656.23 AFI84259.1 - 5.5e-06 26.5 0.0 7.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AFI84259.1 - 1.6e-05 24.5 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 AFI84259.1 - 3.4e-05 23.9 0.2 0.00022 21.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain Wzy_C PF04932.15 AFI84260.1 - 1e-16 61.0 10.0 1e-16 61.0 10.0 4.0 2 2 1 4 4 4 1 O-Antigen ligase Polysacc_synt PF01943.17 AFI84261.1 - 6.1e-18 65.2 28.9 6.1e-18 65.2 28.9 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 AFI84261.1 - 1.5e-17 63.8 17.3 1.5e-17 63.8 17.3 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AFI84261.1 - 1.7e-13 50.8 25.6 1.7e-13 50.8 25.6 4.4 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 AFI84261.1 - 0.0056 15.3 47.2 0.0095 14.6 46.7 1.7 1 1 0 1 1 1 1 Lipid II flippase MurJ EVC2_like PF12297.8 AFI84261.1 - 0.47 9.1 1.2 1.7 7.2 1.2 2.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Glycos_transf_1 PF00534.20 AFI84262.1 - 1e-20 74.0 0.0 3.1e-20 72.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI84262.1 - 1.2e-18 67.8 0.0 3.9e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI84262.1 - 8.2e-15 55.2 0.0 1.4e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI84262.1 - 4.4e-09 37.0 0.0 8.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Hexapep PF00132.24 AFI84263.1 - 1.1e-06 28.1 2.9 4.4e-06 26.2 0.1 2.4 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AFI84263.1 - 0.00022 20.9 1.2 1.5 8.6 0.0 3.6 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AFI84264.1 - 7e-09 35.1 1.2 2.1e-08 33.5 0.9 1.9 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AFI84264.1 - 1.3e-06 28.1 2.6 3.4e-06 26.7 2.0 1.9 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Glycos_transf_2 PF00535.26 AFI84265.1 - 1.2e-22 80.6 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AFI84265.1 - 1.1e-16 61.4 0.0 2.1e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AFI84265.1 - 0.00058 19.8 1.6 0.0045 16.9 0.5 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 AFI84265.1 - 0.0018 17.8 0.3 0.0045 16.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AFI84265.1 - 0.003 18.0 0.0 0.0069 16.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 AFI84265.1 - 0.091 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glycos_transf_1 PF00534.20 AFI84266.1 - 1.4e-36 125.6 0.0 4.1e-36 124.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI84266.1 - 6.7e-30 104.2 0.0 1.3e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI84266.1 - 1e-13 51.7 0.0 2.5e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AFI84266.1 - 7.5e-05 23.0 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AFI84266.1 - 0.0012 19.3 0.0 0.0043 17.5 0.0 2.1 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Methyltransf_11 PF08241.12 AFI84267.1 - 2.6e-13 50.5 0.0 4.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI84267.1 - 9.2e-11 41.8 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI84267.1 - 9.2e-08 32.7 0.1 7.1e-07 29.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI84267.1 - 4.6e-07 29.8 0.0 1.4e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84267.1 - 2.4e-06 28.2 0.0 8.1e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 AFI84267.1 - 2.7e-05 24.5 0.1 8.2e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_29 PF03141.16 AFI84267.1 - 8.8e-05 21.2 0.0 0.22 10.0 0.0 2.1 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 AFI84267.1 - 0.00086 18.7 0.0 0.01 15.2 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AFI84267.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 AFI84267.1 - 0.01 15.2 0.0 0.026 13.8 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 AFI84267.1 - 0.012 15.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 DNA methylase MetW PF07021.12 AFI84267.1 - 0.05 13.2 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 AFI84267.1 - 0.085 12.7 0.0 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_9 PF08003.11 AFI84267.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Alpha-L-AF_C PF06964.12 AFI84268.1 - 0.00014 22.0 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_39 PF01229.17 AFI84268.1 - 0.0013 17.4 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase PF00150.18 AFI84268.1 - 0.065 12.6 0.1 0.27 10.6 0.1 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DRTGG PF07085.12 AFI84268.1 - 0.15 11.8 0.0 0.51 10.1 0.0 1.9 1 0 0 1 1 1 0 DRTGG domain DUF1972 PF09314.11 AFI84269.1 - 3.9e-22 78.7 0.1 8.9e-22 77.6 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1972) Glycos_transf_1 PF00534.20 AFI84269.1 - 2e-08 34.0 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI84269.1 - 7.6e-08 32.5 0.1 1.5e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AFI84269.1 - 0.00018 21.9 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI84269.1 - 0.0072 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AFI84269.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_tran_WecB PF03808.13 AFI84271.1 - 4.7e-49 166.6 0.0 8.9e-49 165.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family STAS_2 PF13466.6 AFI84271.1 - 2.5e-05 24.5 0.0 4.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain YcgR_2 PF12945.7 AFI84271.1 - 0.04 14.1 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Flagellar protein YcgR Exosortase_EpsH PF09721.10 AFI84272.1 - 6e-59 199.7 33.4 9.4e-59 199.0 33.4 1.3 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF3485 PF11984.8 AFI84272.1 - 2.4e-51 174.4 0.0 3.6e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3485) TPR_14 PF13428.6 AFI84273.1 - 8.3e-51 166.3 32.0 0.0011 19.6 0.1 19.1 4 4 14 19 19 19 13 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84273.1 - 1.4e-49 162.2 21.5 0.0021 18.0 0.0 16.4 17 0 0 17 17 16 10 Tetratricopeptide repeat TPR_8 PF13181.6 AFI84273.1 - 1e-45 150.1 30.9 0.00014 21.8 0.0 17.7 19 0 0 19 19 18 9 Tetratricopeptide repeat TPR_16 PF13432.6 AFI84273.1 - 6.7e-45 151.5 10.3 5.2e-06 27.0 0.0 13.8 10 3 3 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 AFI84273.1 - 4.4e-44 148.8 47.9 3.4e-07 30.7 2.1 13.1 5 3 10 15 15 15 11 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84273.1 - 1.8e-41 138.3 17.8 0.0021 17.8 0.0 14.9 15 0 0 15 15 14 9 Tetratricopeptide repeat TPR_12 PF13424.6 AFI84273.1 - 8.6e-28 96.5 37.0 6.4e-05 23.2 0.2 12.2 6 4 5 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 AFI84273.1 - 1.7e-27 94.8 25.0 4.9e-06 26.1 0.4 12.1 9 3 3 12 12 11 7 TPR repeat TPR_17 PF13431.6 AFI84273.1 - 4.5e-26 89.3 17.4 0.063 13.7 0.0 14.1 14 1 0 14 14 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 AFI84273.1 - 2.8e-22 77.8 32.0 0.025 15.2 0.0 17.6 20 0 0 20 20 18 2 Tetratricopeptide repeat TPR_7 PF13176.6 AFI84273.1 - 2.4e-21 74.1 25.8 0.00022 21.0 0.0 13.6 15 1 0 15 15 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI84273.1 - 1.5e-20 73.2 16.3 0.00011 22.3 0.1 8.4 4 2 6 10 10 10 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AFI84273.1 - 6.5e-18 64.7 19.2 0.056 13.6 0.0 11.1 8 3 4 13 13 13 6 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AFI84273.1 - 9.7e-11 41.4 10.6 0.0075 15.9 0.3 6.6 5 2 2 7 7 7 3 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 AFI84273.1 - 2.5e-09 37.1 20.4 1 9.5 0.1 9.6 6 2 4 10 10 10 3 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 AFI84273.1 - 6.6e-09 35.4 31.5 0.18 11.7 0.1 13.1 13 0 0 13 13 13 2 Tetratricopeptide repeat NARP1 PF12569.8 AFI84273.1 - 6.1e-08 32.0 20.3 0.00033 19.7 1.1 7.2 3 2 2 7 7 7 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 AFI84273.1 - 2.8e-07 30.8 26.9 0.69 10.3 0.7 9.1 5 2 4 10 10 9 2 Tetratricopeptide repeat ChAPs PF09295.10 AFI84273.1 - 3.3e-07 29.7 16.6 0.00068 18.7 4.3 4.8 2 2 3 5 5 5 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 AFI84273.1 - 3.7e-07 29.6 33.6 0.24 10.6 0.2 8.5 2 2 7 10 10 10 5 Tetratricopeptide repeat TPR_21 PF09976.9 AFI84273.1 - 1.5e-06 28.0 32.1 0.13 12.0 0.3 8.7 4 3 4 9 9 9 4 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 AFI84273.1 - 2.9e-06 27.4 0.5 1.4 9.7 0.0 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_5 PF12688.7 AFI84273.1 - 9.2e-05 22.7 9.4 0.095 12.9 1.1 5.1 3 2 3 6 6 6 2 Tetratrico peptide repeat BTAD PF03704.17 AFI84273.1 - 0.0015 19.0 20.0 2.3 8.6 0.3 7.2 4 3 3 7 7 7 2 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 AFI84273.1 - 0.0025 18.3 17.3 5.9 7.3 0.1 6.6 5 1 1 7 7 7 0 Alkyl sulfatase dimerisation DUF4192 PF13830.6 AFI84273.1 - 0.0061 16.7 0.2 0.27 11.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4192) Coatomer_E PF04733.14 AFI84273.1 - 0.026 13.9 25.5 0.033 13.6 0.8 5.8 4 2 1 5 5 5 0 Coatomer epsilon subunit DUF4919 PF16266.5 AFI84273.1 - 0.042 13.8 8.1 3.8 7.4 0.1 5.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4919) TraE PF05309.11 AFI84273.1 - 0.055 12.8 0.3 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 TraE protein TPR_3 PF07720.12 AFI84273.1 - 0.061 13.3 6.2 18 5.5 0.3 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat HemY_N PF07219.13 AFI84273.1 - 0.28 11.4 16.8 14 6.0 0.2 7.1 7 2 1 8 8 8 0 HemY protein N-terminus ANAPC5 PF12862.7 AFI84273.1 - 1.3 9.1 6.2 1.4 9.0 0.1 4.0 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 5 Ni_hydr_CYTB PF01292.20 AFI84274.1 - 3.4e-25 88.7 8.8 4e-25 88.5 8.8 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 AFI84274.1 - 0.011 15.9 0.5 0.17 12.1 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF3935 PF13071.6 AFI84274.1 - 0.048 14.2 2.5 3.4 8.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) LysR_substrate PF03466.20 AFI84275.1 - 7.5e-46 156.1 0.5 9.8e-46 155.7 0.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AFI84275.1 - 5e-17 61.6 0.0 1.1e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_50 PF18024.1 AFI84275.1 - 0.00082 18.9 0.1 0.0016 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AFI84275.1 - 0.011 15.4 0.2 0.011 15.4 0.2 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 AFI84275.1 - 0.028 13.9 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 PBP_like PF12727.7 AFI84275.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain HTH_Crp_2 PF13545.6 AFI84275.1 - 0.12 12.4 0.6 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain CPSase_L_D2 PF02786.17 AFI84276.1 - 1.8e-76 256.3 0.1 2.5e-76 255.9 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AFI84276.1 - 5.1e-44 149.3 0.0 1.2e-43 148.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AFI84276.1 - 2.4e-40 137.0 0.0 4.7e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AFI84276.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AFI84276.1 - 2.9e-07 30.2 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AFI84276.1 - 0.00036 20.2 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AFI84276.1 - 0.00058 20.0 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AFI84276.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain PYC_OADA PF02436.18 AFI84277.1 - 4.4e-56 189.8 0.0 9.2e-56 188.7 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 AFI84277.1 - 3.9e-49 167.6 0.0 5.3e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AFI84277.1 - 9.5e-17 60.6 2.0 1.9e-16 59.7 2.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AFI84277.1 - 1.6e-08 34.2 0.8 0.0023 17.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 AFI84277.1 - 0.0007 19.5 0.2 0.0016 18.4 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 AFI84277.1 - 0.0016 18.3 0.6 0.0088 16.0 0.5 2.2 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AFI84277.1 - 0.0027 17.0 0.3 0.56 9.4 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI84277.1 - 0.025 15.3 0.5 3.5 8.4 0.1 2.6 2 0 0 2 2 2 0 HlyD family secretion protein Acyl_transf_3 PF01757.22 AFI84278.1 - 1.1e-23 83.9 42.8 1.4e-23 83.6 42.8 1.1 1 0 0 1 1 1 1 Acyltransferase family OpgC_C PF10129.9 AFI84278.1 - 3.8e-08 32.6 20.3 2.4e-06 26.7 11.2 2.2 2 0 0 2 2 2 2 OpgC protein Cys_Met_Meta_PP PF01053.20 AFI84280.1 - 6.5e-106 354.1 0.0 8e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AFI84280.1 - 4.4e-08 32.7 0.0 6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AFI84280.1 - 9.8e-07 28.0 0.0 1.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AFI84280.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Fic PF02661.18 AFI84282.1 - 0.067 14.1 0.0 0.16 12.9 0.0 1.7 1 1 0 1 1 1 0 Fic/DOC family PRAI PF00697.22 AFI84282.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase ABC_tran PF00005.27 AFI84283.1 - 2e-27 96.4 0.0 2.8e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI84283.1 - 2.6e-08 34.1 0.0 0.0057 16.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI84283.1 - 3.3e-08 33.3 0.1 7.1e-08 32.1 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AFI84283.1 - 9.8e-07 28.8 0.0 1.8e-06 28.0 0.0 1.5 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 AFI84283.1 - 0.00035 19.8 0.0 0.00047 19.4 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 AFI84283.1 - 0.00061 20.4 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI84283.1 - 0.0016 18.7 0.0 0.0052 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI84283.1 - 0.002 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI84283.1 - 0.0034 17.8 0.0 0.048 14.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AFI84283.1 - 0.0062 16.5 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 AFI84283.1 - 0.0085 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 AFI84283.1 - 0.019 15.4 0.0 0.09 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 AFI84283.1 - 0.061 13.0 0.3 1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AFI84283.1 - 0.074 13.6 0.0 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AFI84283.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AFI84283.1 - 0.15 12.5 0.0 2.6 8.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 AFI84283.1 - 0.17 11.0 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit BPD_transp_1 PF00528.22 AFI84284.1 - 2.9e-22 79.3 18.7 2.9e-22 79.3 18.7 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AFI84285.1 - 9.5e-21 74.4 20.0 9.5e-21 74.4 20.0 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PBP_like_2 PF12849.7 AFI84286.1 - 8.8e-59 199.5 5.2 1.2e-58 199.1 5.2 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AFI84286.1 - 6.5e-11 41.7 0.0 1.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 PBP superfamily domain PQQ PF01011.21 AFI84287.1 - 4.2e-29 99.1 16.3 2.1e-09 36.8 0.1 7.2 7 0 0 7 7 7 5 PQQ enzyme repeat PQQ_2 PF13360.6 AFI84287.1 - 5.8e-19 68.6 0.0 8.6e-09 35.3 0.0 2.7 2 1 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 AFI84287.1 - 5.1e-12 45.9 7.5 0.00017 22.0 0.2 5.8 5 0 0 5 5 5 4 PQQ-like domain GXGXG PF01493.19 AFI84287.1 - 0.085 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 GXGXG motif DUF4061 PF13270.6 AFI84288.1 - 0.022 15.1 0.1 0.046 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Aminotran_1_2 PF00155.21 AFI84289.1 - 5.7e-70 236.3 0.0 6.5e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AFI84289.1 - 2.7e-06 26.4 0.0 4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 AFI84289.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AFI84289.1 - 0.00013 21.1 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AFI84289.1 - 0.0027 16.3 0.0 0.0051 15.4 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3606 PF12244.8 AFI84289.1 - 0.16 11.9 0.2 31 4.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) UvrB_inter PF17757.1 AFI84290.1 - 2.2e-33 114.3 0.4 6.4e-33 112.8 0.4 1.8 1 0 0 1 1 1 1 UvrB interaction domain UvrB PF12344.8 AFI84290.1 - 2.2e-22 78.6 0.2 5.3e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AFI84290.1 - 2.5e-18 66.4 0.1 6.1e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AFI84290.1 - 5.7e-09 36.2 0.0 6.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 AFI84290.1 - 2e-07 30.5 5.6 2e-07 30.5 5.6 2.7 3 0 0 3 3 3 1 UvrB/uvrC motif AAA_30 PF13604.6 AFI84290.1 - 6.4e-06 26.0 0.0 2.1e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AFI84290.1 - 0.00011 22.0 0.1 0.004 17.0 0.0 3.1 3 1 0 3 3 3 1 DEAD/DEAH box helicase HCMV_UL139 PF12507.8 AFI84290.1 - 0.0023 18.3 0.6 0.0068 16.8 0.2 2.0 2 0 0 2 2 1 1 Human Cytomegalovirus UL139 protein AAA_22 PF13401.6 AFI84290.1 - 0.025 14.8 1.0 1 9.7 0.0 3.5 4 1 0 4 4 4 0 AAA domain AAA_19 PF13245.6 AFI84290.1 - 0.026 14.9 0.0 5.9 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 AFI84290.1 - 0.031 14.3 0.3 0.88 9.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 AFI84290.1 - 0.033 14.6 2.6 1.3 9.4 0.0 4.0 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) CorA PF01544.18 AFI84290.1 - 0.043 13.1 7.6 0.59 9.4 0.1 3.2 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Kinesin PF00225.23 AFI84290.1 - 0.073 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain DUF4368 PF14287.6 AFI84290.1 - 0.094 13.0 0.6 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) IF2_N PF04760.15 AFI84290.1 - 0.14 12.0 0.5 0.44 10.4 0.5 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region NACHT PF05729.12 AFI84290.1 - 0.16 11.9 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_MLP1_2 PF07926.12 AFI84290.1 - 2.1 8.4 12.0 3.5 7.7 0.6 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein tRNA-synt_2b PF00587.25 AFI84291.1 - 3.7e-44 150.8 0.0 9.6e-44 149.5 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AFI84291.1 - 2.6e-23 82.0 0.4 6.1e-23 80.8 0.4 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 AFI84291.1 - 1.1e-17 63.9 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 AFI84291.1 - 8.1e-14 51.4 0.7 7.7e-13 48.3 0.1 2.6 2 1 0 2 2 2 1 TGS domain MgtE_N PF03448.17 AFI84291.1 - 0.019 15.6 1.1 0.019 15.6 1.1 2.8 3 0 0 3 3 3 0 MgtE intracellular N domain IF3_C PF00707.22 AFI84292.1 - 5.3e-39 132.1 0.6 7.7e-39 131.6 0.6 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AFI84292.1 - 1.4e-17 63.7 0.8 3.6e-17 62.4 0.6 1.9 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Polo_box_3 PF18544.1 AFI84292.1 - 0.086 13.5 2.2 9.3 7.0 0.2 2.1 1 1 1 2 2 2 0 Polo box domain Ribosomal_L35p PF01632.19 AFI84293.1 - 1.5e-24 86.2 9.8 1.6e-24 86.1 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 RAG1_imp_bd PF12560.8 AFI84293.1 - 0.023 14.3 1.2 0.026 14.1 1.2 1.0 1 0 0 1 1 1 0 RAG1 importin binding TruB_C_2 PF16198.5 AFI84293.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Ribosomal_L20 PF00453.18 AFI84294.1 - 1.2e-47 160.4 7.7 1.4e-47 160.2 7.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 SMC_ScpA PF02616.14 AFI84294.1 - 0.027 14.4 0.2 0.045 13.6 0.1 1.4 1 1 0 1 1 1 0 Segregation and condensation protein ScpA tRNA-synt_2d PF01409.20 AFI84295.1 - 4.2e-105 350.6 0.0 5e-105 350.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AFI84295.1 - 9.9e-20 70.3 1.9 1.6e-19 69.6 1.4 1.6 1 1 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 AFI84295.1 - 0.0031 17.0 0.0 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 AFI84296.1 - 1.6e-72 242.8 0.0 3.5e-72 241.7 0.0 1.6 2 0 0 2 2 2 1 B3/4 domain tRNA_synthFbeta PF17759.1 AFI84296.1 - 6.3e-61 205.5 0.0 9.3e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AFI84296.1 - 2e-26 92.2 0.0 4.3e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AFI84296.1 - 9.2e-23 80.2 0.2 1.8e-22 79.2 0.2 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 AFI84296.1 - 3.6e-20 72.0 0.5 1.3e-19 70.3 0.5 2.0 1 0 0 1 1 1 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 AFI84296.1 - 0.0084 16.3 0.0 11 6.3 0.0 3.4 4 0 0 4 4 4 2 Phe-tRNA synthetase beta subunit B1 domain Bac_DNA_binding PF00216.21 AFI84297.1 - 3.3e-32 110.6 0.1 3.6e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AFI84297.1 - 2.2e-06 27.8 0.0 2.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AFI84297.1 - 0.0003 20.6 0.2 0.00048 19.9 0.2 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AFI84297.1 - 0.048 13.8 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 MerR_1 PF13411.6 AFI84298.1 - 3.6e-23 81.4 0.5 8.2e-23 80.3 0.2 1.7 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AFI84298.1 - 8.7e-12 44.6 0.1 1.6e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 AFI84298.1 - 0.001 19.2 0.1 0.0028 17.8 0.1 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain DUF4158 PF13700.6 AFI84298.1 - 0.0029 17.5 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) Aldo_ket_red PF00248.21 AFI84299.1 - 8.1e-70 235.3 0.0 9.3e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EAL PF00563.20 AFI84300.1 - 1.2e-75 254.1 0.5 2.8e-73 246.3 0.0 2.3 2 0 0 2 2 2 2 EAL domain GGDEF PF00990.21 AFI84300.1 - 2.6e-49 167.0 1.9 1.4e-48 164.7 1.9 2.2 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AFI84300.1 - 8.2e-29 100.0 0.0 3e-28 98.2 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 AFI84300.1 - 1.4e-11 44.5 0.1 3.5e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 PAS fold MarR PF01047.22 AFI84301.1 - 2.7e-18 65.6 2.7 7.6e-18 64.2 1.1 2.2 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AFI84301.1 - 1.2e-13 50.7 0.7 2.8e-13 49.5 0.7 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AFI84301.1 - 1.1e-08 35.4 1.1 1.1e-08 35.4 1.1 2.1 3 0 0 3 3 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AFI84301.1 - 8e-07 28.5 0.2 3.2e-06 26.6 0.2 2.0 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AFI84301.1 - 2.9e-05 23.9 0.1 4.6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 AFI84301.1 - 5.9e-05 23.4 0.9 0.00012 22.5 0.8 1.8 1 1 0 1 1 1 1 Penicillinase repressor Fe_dep_repress PF01325.19 AFI84301.1 - 0.0003 20.9 0.1 0.00077 19.6 0.1 1.7 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 AFI84301.1 - 0.00031 20.6 0.8 0.00057 19.8 0.4 1.7 2 0 0 2 2 1 1 HTH domain TFIIE_alpha PF02002.17 AFI84301.1 - 0.00043 20.1 0.7 0.00092 19.0 0.2 1.8 1 1 1 2 2 2 1 TFIIE alpha subunit HTH_20 PF12840.7 AFI84301.1 - 0.00089 19.3 0.3 0.0027 17.7 0.3 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 AFI84301.1 - 0.0011 19.3 0.4 0.003 17.9 0.3 1.8 1 1 0 1 1 1 1 Transcriptional regulator HxlR PF01638.17 AFI84301.1 - 0.0025 17.6 1.0 0.0062 16.4 0.6 1.7 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 AFI84301.1 - 0.0028 17.5 0.1 0.0063 16.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_DeoR PF08220.12 AFI84301.1 - 0.0032 17.2 0.9 0.0066 16.2 0.9 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Mga PF05043.13 AFI84301.1 - 0.0033 18.0 0.1 0.0091 16.6 0.0 1.8 1 1 0 1 1 1 1 Mga helix-turn-helix domain HTH_IclR PF09339.10 AFI84301.1 - 0.0038 17.0 1.7 0.019 14.8 1.7 2.3 1 1 0 1 1 1 1 IclR helix-turn-helix domain TetR_C_35 PF18556.1 AFI84301.1 - 0.0046 17.1 0.7 0.0089 16.2 0.7 1.4 1 0 0 1 1 1 1 Bacterial Tetracyclin repressor, C-terminal domain PadR PF03551.14 AFI84301.1 - 0.0078 16.1 0.6 0.019 14.9 0.6 1.8 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_26 PF13443.6 AFI84301.1 - 0.0081 16.6 0.3 2.5 8.6 0.1 2.6 1 1 1 2 2 2 1 Cro/C1-type HTH DNA-binding domain Sulfolobus_pRN PF05584.11 AFI84301.1 - 0.0084 16.1 0.5 0.016 15.2 0.2 1.7 1 1 1 2 2 2 1 Sulfolobus plasmid regulatory protein GntR PF00392.21 AFI84301.1 - 0.011 15.4 0.4 0.025 14.2 0.4 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AFI84301.1 - 0.019 14.9 1.3 0.044 13.8 0.9 1.9 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_31 PF13560.6 AFI84301.1 - 0.081 13.3 0.7 4 7.9 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AFI84301.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 AFI84301.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_10 PF04967.12 AFI84301.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.6 3 1 1 4 4 3 0 HTH DNA binding domain DUF480 PF04337.12 AFI84301.1 - 0.24 11.5 4.1 1.3 9.1 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF480 HTH_37 PF13744.6 AFI84301.1 - 0.36 10.8 2.9 6.9 6.7 0.1 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain Acetyltransf_1 PF00583.25 AFI84302.1 - 3.4e-12 46.6 0.0 4.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 AFI84302.1 - 2.9e-05 24.8 0.0 3.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AFI84302.1 - 0.00027 21.3 0.0 0.00041 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AFI84302.1 - 0.0027 17.6 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 AFI84302.1 - 0.0029 17.5 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AFI84302.1 - 0.0077 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Aminotran_3 PF00202.21 AFI84303.1 - 2.1e-84 283.6 0.0 2.5e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AFI84303.1 - 0.00034 19.9 0.0 0.0019 17.5 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AFI84303.1 - 0.045 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ectoine_synth PF06339.12 AFI84304.1 - 2.3e-60 202.4 0.1 2.6e-60 202.2 0.1 1.0 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 AFI84304.1 - 9.9e-06 25.2 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 AFI84304.1 - 0.0017 18.2 0.4 0.0023 17.8 0.4 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 AFI84304.1 - 0.0088 15.7 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AA_kinase PF00696.28 AFI84305.1 - 2.3e-29 102.7 1.5 3.1e-29 102.3 0.2 1.8 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 AFI84305.1 - 1e-09 38.1 0.2 2.7e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 AFI84305.1 - 3.1e-05 23.6 0.1 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 1 ACT domain ANAPC5 PF12862.7 AFI84305.1 - 0.0047 17.0 0.6 9.7 6.3 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 ACT_6 PF13740.6 AFI84305.1 - 0.18 11.8 0.5 3.7 7.6 0.1 2.6 2 0 0 2 2 2 0 ACT domain PEP-utilisers_N PF05524.13 AFI84305.1 - 0.31 11.2 2.4 0.7 10.1 0.1 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Laminin_II PF06009.12 AFI84305.1 - 0.37 10.8 3.6 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II TPR_1 PF00515.28 AFI84306.1 - 5.9e-09 35.4 4.7 5.2e-05 22.9 0.8 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84306.1 - 3.3e-08 33.0 4.3 0.00069 19.5 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ChAPs PF09295.10 AFI84306.1 - 1.6e-06 27.4 2.3 2e-06 27.1 0.4 1.8 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 AFI84306.1 - 1.7e-05 25.2 0.8 4.3e-05 23.9 0.4 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI84306.1 - 0.0005 20.2 3.7 0.001 19.3 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 AFI84306.1 - 0.00056 20.1 0.8 0.0083 16.4 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AFI84306.1 - 0.00069 20.1 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation TPR_10 PF13374.6 AFI84306.1 - 0.0014 18.4 0.4 0.005 16.7 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 AFI84306.1 - 0.0027 18.0 0.6 0.0095 16.2 0.1 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 AFI84306.1 - 0.0052 16.9 1.1 0.0052 16.9 1.1 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AFI84306.1 - 0.0053 17.0 1.0 0.013 15.7 1.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 AFI84306.1 - 0.0091 16.7 0.8 2.4 9.2 0.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat PilJ PF13675.6 AFI84306.1 - 0.023 14.7 4.3 0.98 9.5 0.8 2.6 3 0 0 3 3 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_6 PF13174.6 AFI84306.1 - 0.03 15.0 0.4 0.11 13.1 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_S46 PF10459.9 AFI84306.1 - 0.031 12.9 1.8 0.38 9.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 Exonuc_VII_L PF02601.15 AFI84306.1 - 0.039 13.5 2.5 0.048 13.2 2.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_9 PF13371.6 AFI84306.1 - 0.051 13.7 0.8 4.7 7.4 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF948 PF06103.11 AFI84306.1 - 0.052 13.8 2.2 0.5 10.7 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_7 PF13176.6 AFI84306.1 - 0.097 12.7 5.2 1.4 9.1 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4562 PF15123.6 AFI84306.1 - 0.11 12.4 0.2 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) Peptidase_S49_N PF08496.10 AFI84306.1 - 0.14 12.3 1.8 0.2 11.7 0.9 1.7 1 1 1 2 2 2 0 Peptidase family S49 N-terminal TPR_11 PF13414.6 AFI84306.1 - 0.14 11.9 3.0 2.9 7.7 0.3 2.7 2 1 1 3 3 3 0 TPR repeat Spc24 PF08286.11 AFI84306.1 - 0.16 12.2 3.1 0.35 11.1 1.2 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Mis12 PF05859.12 AFI84306.1 - 1.8 8.6 8.3 4.9 7.2 6.7 2.6 1 1 0 1 1 1 0 Mis12 protein CCDC-167 PF15188.6 AFI84306.1 - 2.7 8.4 10.1 0.36 11.2 3.1 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1690 PF07956.11 AFI84306.1 - 4.7 7.6 9.8 12 6.3 0.2 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Chalcone_3 PF16036.5 AFI84307.1 - 2.9e-17 63.3 0.1 3.4e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Chalcone isomerase-like PA14 PF07691.12 AFI84307.1 - 0.06 13.1 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 PA14 domain DUF2358 PF10184.9 AFI84308.1 - 0.086 13.1 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) DDE_Tnp_1_2 PF13586.6 AFI84309.1 - 6e-18 65.0 0.7 6.7e-18 64.9 0.7 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI84309.1 - 4.6e-10 39.5 3.7 4.7e-08 32.9 3.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI84309.1 - 1.3e-06 28.2 0.1 1.6e-06 27.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AFI84309.1 - 2.2e-06 27.7 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Cellulase PF00150.18 AFI84309.1 - 0.047 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4096 PF13340.6 AFI84310.1 - 1.4e-25 89.3 3.8 2.6e-25 88.4 3.8 1.4 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) FA_desaturase PF00487.24 AFI84311.1 - 5e-21 75.7 23.6 7.3e-21 75.2 23.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF2975 PF11188.8 AFI84311.1 - 0.0023 17.8 2.9 0.26 11.2 0.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2975) DUF624 PF04854.14 AFI84311.1 - 0.13 12.4 5.3 0.48 10.6 5.3 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DUF456 PF04306.13 AFI84311.1 - 0.38 11.0 7.1 0.3 11.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Keratin_assoc PF09775.9 AFI84311.1 - 0.6 9.8 7.2 0.3 10.7 0.4 2.2 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Amino_oxidase PF01593.24 AFI84312.1 - 1.5e-22 80.6 0.0 5e-22 78.8 0.0 1.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AFI84312.1 - 4.2e-16 58.9 0.3 3.7e-15 55.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AFI84312.1 - 1.5e-12 47.8 0.4 1.3e-08 34.8 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 AFI84312.1 - 3.9e-06 26.3 0.0 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 AFI84312.1 - 7.4e-06 25.4 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI84312.1 - 3e-05 24.5 0.3 0.0068 16.9 0.1 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AFI84312.1 - 0.00016 21.7 0.0 0.061 13.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 AFI84312.1 - 0.00016 20.5 0.1 0.33 9.6 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein MCRA PF06100.11 AFI84312.1 - 0.00068 18.6 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_3 PF13738.6 AFI84312.1 - 0.0015 17.8 0.1 0.076 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AFI84312.1 - 0.003 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Prenylcys_lyase PF07156.14 AFI84312.1 - 0.026 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Prenylcysteine lyase FMO-like PF00743.19 AFI84312.1 - 0.043 12.3 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 AFI84312.1 - 0.061 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 AFI84312.1 - 0.13 12.0 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1365 PF07103.11 AFI84313.1 - 3.5e-74 249.5 5.5 4e-74 249.3 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF1759 PF03564.15 AFI84313.1 - 0.1 12.5 0.3 2.5 8.0 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) DUF3889 PF13028.6 AFI84313.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) CMAS PF02353.20 AFI84314.1 - 2.5e-78 263.2 0.1 3.2e-78 262.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AFI84314.1 - 3.3e-08 34.1 0.0 6.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI84314.1 - 3.8e-06 27.5 0.0 7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI84314.1 - 4.4e-05 23.4 0.0 6.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84314.1 - 6.1e-05 23.7 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AFI84314.1 - 0.0022 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 ADH_zinc_N PF00107.26 AFI84314.1 - 0.0024 17.8 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_PK PF05891.12 AFI84314.1 - 0.046 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 AFI84314.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AFI84314.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2878 PF11086.8 AFI84315.1 - 1.4e-42 145.6 23.5 1.6e-42 145.3 23.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2878) DUF1295 PF06966.12 AFI84316.1 - 4.5e-68 229.3 8.9 4.5e-68 229.3 8.9 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 AFI84316.1 - 7.4e-07 29.3 8.9 1.7e-06 28.1 8.0 2.1 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 AFI84316.1 - 0.0024 18.2 0.4 0.0068 16.8 0.4 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 AFI84316.1 - 0.0028 18.0 0.4 0.0028 18.0 0.4 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ArsP_2 PF11449.8 AFI84316.1 - 0.072 12.3 1.3 0.11 11.6 0.9 1.6 2 0 0 2 2 2 0 Putative, 10TM heavy-metal exporter CMAS PF02353.20 AFI84317.1 - 7.6e-39 133.6 2.1 1.1e-38 133.2 2.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 AFI84317.1 - 6.4e-15 55.6 0.0 1.6e-14 54.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI84317.1 - 3.3e-14 53.3 0.0 5.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84317.1 - 3.9e-12 46.8 0.0 8.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI84317.1 - 7.6e-12 45.4 0.1 1.5e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI84317.1 - 1.6e-11 44.2 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AFI84317.1 - 9.6e-09 35.0 0.0 3.3e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.11 AFI84317.1 - 1.8e-08 34.3 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 AFI84317.1 - 3.2e-06 26.7 0.0 6.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 AFI84317.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 AFI84317.1 - 0.00028 20.0 0.1 0.00086 18.4 0.1 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 AFI84317.1 - 0.00055 19.6 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F DUF938 PF06080.12 AFI84317.1 - 0.00081 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 AFI84317.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 AFI84317.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 AFI84317.1 - 0.0034 16.5 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase DUF268 PF03269.14 AFI84317.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.6 1 1 1 2 2 2 0 Caenorhabditis protein of unknown function, DUF268 GidB PF02527.15 AFI84317.1 - 0.057 12.7 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.19 AFI84317.1 - 0.17 12.0 0.0 1.6 8.8 0.0 1.9 1 1 1 2 2 2 0 FtsJ-like methyltransferase HATPase_c PF02518.26 AFI84318.1 - 3.5e-18 66.1 0.0 7.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84318.1 - 5.4e-12 45.6 1.2 1.2e-11 44.4 1.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AFI84318.1 - 0.00066 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI84318.1 - 0.0067 16.3 0.1 0.042 13.7 0.1 2.3 2 1 0 2 2 2 1 GHKL domain HAMP PF00672.25 AFI84318.1 - 0.012 16.0 0.3 0.035 14.5 0.0 2.0 2 0 0 2 2 2 0 HAMP domain TMEM252 PF15664.5 AFI84318.1 - 0.18 11.5 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family Response_reg PF00072.24 AFI84319.1 - 2.5e-30 104.9 0.1 4.2e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84319.1 - 8.5e-19 67.4 0.3 1.9e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Fer2_BFD PF04324.15 AFI84320.1 - 3.3e-07 30.5 0.6 4e-07 30.3 0.6 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Ferritin PF00210.24 AFI84321.1 - 6.9e-40 136.3 4.3 8e-40 136.1 4.3 1.0 1 0 0 1 1 1 1 Ferritin-like domain DUF1241 PF06840.11 AFI84321.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Queuosine_synth PF02547.15 AFI84322.1 - 6.6e-136 452.7 0.0 7.5e-136 452.5 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein SpoU_methylase PF00588.19 AFI84323.1 - 1.8e-33 115.7 0.0 2.7e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Arg_decarbox_C PF17944.1 AFI84323.1 - 0.11 13.1 0.3 9.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Hexapep PF00132.24 AFI84324.1 - 3.2e-10 39.3 7.4 2.6e-05 23.8 0.5 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 AFI84324.1 - 0.0054 17.1 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 AFI84324.1 - 0.0079 15.9 9.1 0.6 9.9 0.6 2.9 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Rrf2 PF02082.20 AFI84325.1 - 1.7e-28 98.8 0.2 2.5e-28 98.2 0.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_47 PF16221.5 AFI84325.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 winged helix-turn-helix MarR_2 PF12802.7 AFI84325.1 - 0.00045 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 MarR family YjhX_toxin PF09857.9 AFI84325.1 - 0.0016 18.4 0.0 0.0064 16.4 0.0 2.0 2 0 0 2 2 2 1 Putative toxin of bacterial toxin-antitoxin pair DUF4043 PF13252.6 AFI84325.1 - 0.0051 16.0 0.0 0.0062 15.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4043) HrcA_DNA-bdg PF03444.15 AFI84325.1 - 0.0051 16.4 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MarR PF01047.22 AFI84325.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AFI84325.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AFI84325.1 - 0.055 13.4 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AFI84325.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HemN_C PF06969.16 AFI84325.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 HemN C-terminal domain Aminotran_5 PF00266.19 AFI84326.1 - 3.9e-83 279.4 0.4 4.9e-83 279.1 0.4 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AFI84326.1 - 2.4e-10 40.1 0.1 4.6e-10 39.2 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AFI84326.1 - 3.8e-06 26.4 0.2 5.7e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AFI84326.1 - 0.0037 16.6 0.5 0.0059 16.0 0.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Nbl1_Borealin_N PF10444.9 AFI84326.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Fe-S_biosyn PF01521.20 AFI84327.1 - 4e-21 75.3 0.1 4.6e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_3 PF00202.21 AFI84328.1 - 1e-128 429.5 0.0 1.1e-128 429.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AFI84328.1 - 0.0064 15.8 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AFI84328.1 - 0.018 14.2 0.0 0.41 9.8 0.0 2.3 1 1 1 2 2 2 0 Aminotransferase class I and II AhpC-TSA PF00578.21 AFI84329.1 - 1.4e-35 121.9 0.0 1.7e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AFI84329.1 - 2.3e-14 53.3 0.0 2.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AFI84329.1 - 2.2e-07 30.6 0.0 4.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 AFI84329.1 - 3.4e-06 27.0 0.0 1.9e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC Pyr_redox_2 PF07992.14 AFI84330.1 - 1.4e-47 162.3 5.5 2.1e-47 161.8 5.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AFI84330.1 - 5.2e-19 68.6 3.7 8.4e-16 58.1 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI84330.1 - 6.4e-14 52.3 11.0 2e-12 47.5 1.0 3.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin_3 PF13192.6 AFI84330.1 - 1.5e-10 40.9 0.4 1.4e-09 37.9 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin domain HI0933_like PF03486.14 AFI84330.1 - 3.4e-08 32.6 8.9 0.0083 14.9 0.1 3.7 3 0 0 3 3 3 3 HI0933-like protein GIDA PF01134.22 AFI84330.1 - 1e-07 31.4 15.1 0.0012 18.0 0.8 3.7 2 2 1 4 4 4 3 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AFI84330.1 - 4.3e-07 29.4 13.4 0.0058 15.8 1.6 4.2 3 1 1 4 4 4 2 FAD binding domain DAO PF01266.24 AFI84330.1 - 2.1e-05 24.3 10.6 0.2 11.2 1.3 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AFI84330.1 - 6.1e-05 22.4 1.4 0.00047 19.5 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AFI84330.1 - 0.0003 20.3 1.8 0.0003 20.3 1.8 4.2 2 2 1 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 AFI84330.1 - 0.00086 18.5 0.5 0.0068 15.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AFI84330.1 - 0.00092 18.5 1.7 0.014 14.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 AFI84330.1 - 0.0032 16.8 1.7 1.4 8.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AFI84330.1 - 0.028 14.8 1.0 12 6.3 0.1 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 AFI84330.1 - 0.12 12.7 3.8 0.51 10.6 0.5 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AFI84330.1 - 0.22 11.5 5.5 1.3 9.0 0.1 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Glutaredoxin PF00462.24 AFI84330.1 - 0.39 11.0 3.7 0.58 10.4 0.0 3.2 4 0 0 4 4 4 0 Glutaredoxin Response_reg PF00072.24 AFI84331.1 - 1.5e-26 92.7 0.0 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AFI84331.1 - 1.6e-16 59.6 0.1 2.9e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AFI84331.1 - 0.00011 21.8 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AFI84331.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AFI84331.1 - 0.0017 18.1 0.0 0.0083 15.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AFI84331.1 - 0.0021 18.0 0.4 0.0046 16.9 0.4 1.7 1 0 0 1 1 1 1 HTH domain HTH_29 PF13551.6 AFI84331.1 - 0.0082 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4 PF04545.16 AFI84331.1 - 0.0091 15.5 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 AFI84331.1 - 0.014 14.9 1.4 0.047 13.3 0.5 2.4 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Phage_terminase PF10668.9 AFI84331.1 - 0.022 14.8 0.1 0.053 13.5 0.1 1.7 1 0 0 1 1 1 0 Phage terminase small subunit HTH_Tnp_ISL3 PF13542.6 AFI84331.1 - 0.033 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 AFI84331.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.22 AFI84331.1 - 0.096 12.6 0.2 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 MarR family HTH_7 PF02796.15 AFI84331.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HisKA_3 PF07730.13 AFI84332.1 - 9e-10 38.9 0.1 9e-10 38.9 0.1 2.6 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 AFI84332.1 - 2.4e-05 24.8 0.5 0.00011 22.7 0.5 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AFI84332.1 - 0.12 12.7 3.5 0.13 12.6 0.4 2.8 3 2 1 4 4 4 0 HAMP domain AAA_3 PF07726.11 AFI84333.1 - 3.7e-24 85.1 0.0 5.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI84333.1 - 1.3e-15 57.6 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 AFI84333.1 - 3e-13 49.4 0.0 7.2e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 AFI84333.1 - 6.5e-06 26.6 0.0 0.00035 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 AFI84333.1 - 8.9e-05 22.3 0.0 0.045 13.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 AFI84333.1 - 0.00017 21.4 0.1 0.02 14.6 0.1 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AFI84333.1 - 0.00036 21.0 0.0 0.00072 20.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI84333.1 - 0.0011 18.4 0.5 0.0024 17.3 0.5 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AFI84333.1 - 0.0012 18.9 0.2 0.002 18.1 0.2 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 AFI84333.1 - 0.0082 16.7 0.1 0.012 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI84333.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 AFI84333.1 - 0.0094 15.7 0.3 0.022 14.5 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI84333.1 - 0.019 14.7 0.1 0.049 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 AFI84333.1 - 0.025 15.1 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AFI84333.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 AFI84333.1 - 0.051 13.4 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_lid_8 PF17868.1 AFI84333.1 - 0.052 13.4 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA lid domain AAA_7 PF12775.7 AFI84333.1 - 0.079 12.5 0.0 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AFG1_ATPase PF03969.16 AFI84333.1 - 0.095 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.12 AFI84333.1 - 0.12 12.3 0.4 0.31 11.0 0.4 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 AFI84333.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 AFI84333.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF3584 PF12128.8 AFI84333.1 - 0.14 9.7 0.2 0.2 9.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MCM PF00493.23 AFI84333.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_19 PF13245.6 AFI84333.1 - 0.22 11.8 0.2 0.49 10.7 0.1 1.6 2 0 0 2 2 1 0 AAA domain VWA_CoxE PF05762.14 AFI84334.1 - 0.00033 20.1 3.0 0.00049 19.5 1.4 1.9 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF58 PF01882.18 AFI84334.1 - 0.0036 17.5 0.1 0.0065 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 AFI84336.1 - 1.4e-11 45.0 0.1 2.7e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AFI84336.1 - 2e-08 34.7 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 AFI84336.1 - 0.0035 16.8 0.1 1.1 8.6 0.0 2.2 1 1 1 2 2 2 2 VWA domain containing CoxE-like protein DUF1194 PF06707.11 AFI84336.1 - 0.0085 15.3 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) TPR_16 PF13432.6 AFI84337.1 - 0.00011 22.7 3.4 0.33 11.7 0.3 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AFI84337.1 - 0.0034 17.0 5.4 1.4 8.7 0.0 4.5 3 2 2 5 5 5 1 TPR repeat TPR_2 PF07719.17 AFI84337.1 - 0.019 15.0 2.6 19 5.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84337.1 - 0.028 14.3 1.2 6.1 6.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AFI84337.1 - 0.82 10.7 3.5 16 6.6 0.1 3.2 2 2 2 4 4 4 0 Tetratricopeptide repeat VWA_2 PF13519.6 AFI84338.1 - 5.9e-07 30.1 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain PilX_N PF14341.6 AFI84339.1 - 0.045 13.7 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 PilX N-terminal YkuD PF03734.14 AFI84340.1 - 7e-16 59.0 0.0 9.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Glyco_hydro_3 PF00933.21 AFI84341.1 - 9e-77 258.6 0.0 1.2e-76 258.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DNA_pol3_alpha PF07733.12 AFI84342.1 - 9.9e-107 356.4 0.0 1.6e-106 355.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AFI84342.1 - 4.9e-68 227.7 0.0 8.3e-68 226.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 AFI84342.1 - 1e-41 143.0 0.0 2e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 AFI84342.1 - 2.7e-29 101.3 0.0 6.4e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 AFI84342.1 - 1.8e-08 34.3 0.1 3.9e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 AFI84342.1 - 0.00072 19.5 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) T2SSE PF00437.20 AFI84343.1 - 2.9e-37 128.2 0.4 4.5e-37 127.6 0.4 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AFI84343.1 - 2.8e-05 24.7 0.0 6.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AFI84343.1 - 9.9e-05 21.8 0.1 0.00022 20.7 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.6 AFI84343.1 - 0.0017 18.1 0.3 0.0036 17.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AFI84343.1 - 0.0041 17.6 0.0 0.0089 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI84343.1 - 0.0042 17.4 0.2 0.0094 16.2 0.2 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AFI84343.1 - 0.0051 16.1 0.2 0.011 15.1 0.0 1.7 2 1 0 2 2 1 1 Zeta toxin Dynamin_N PF00350.23 AFI84343.1 - 0.0066 16.5 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family DUF87 PF01935.17 AFI84343.1 - 0.01 16.0 0.8 0.018 15.1 0.8 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 AFI84343.1 - 0.013 15.9 0.2 0.031 14.7 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 AFI84343.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AFI84343.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AFI84343.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AFI84343.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.6 AFI84343.1 - 0.029 14.7 1.0 0.11 12.8 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 AFI84343.1 - 0.037 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 AFI84343.1 - 0.041 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRP54 PF00448.22 AFI84343.1 - 0.052 13.2 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 AFI84343.1 - 0.069 12.0 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 AFI84343.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Microtub_bd PF16796.5 AFI84343.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding DAP3 PF10236.9 AFI84343.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Kinesin PF00225.23 AFI84343.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_25 PF13481.6 AFI84343.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AFI84343.1 - 0.23 11.6 0.4 0.47 10.6 0.4 1.5 1 1 0 1 1 1 0 AAA domain ACCA PF03255.14 AFI84344.1 - 3.1e-65 218.4 0.3 5.3e-65 217.7 0.0 1.5 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AFI84344.1 - 2.8e-19 69.2 0.0 3.2e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AFI84344.1 - 0.0009 18.8 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) ABC_tran_CTD PF16326.5 AFI84344.1 - 0.25 11.6 2.0 0.21 11.9 0.3 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain ATP_bind_3 PF01171.20 AFI84345.1 - 1.7e-54 184.4 1.0 2.5e-54 183.8 1.0 1.3 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 AFI84345.1 - 1e-21 76.1 0.0 2.2e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 TilS substrate C-terminal domain TilS PF09179.11 AFI84345.1 - 1.2e-18 67.3 0.7 1.2e-18 67.3 0.7 3.4 3 1 0 3 3 3 1 TilS substrate binding domain PAPS_reduct PF01507.19 AFI84345.1 - 0.0031 17.6 0.1 0.01 15.9 0.1 1.9 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 AFI84345.1 - 0.012 15.1 0.2 0.13 11.7 0.1 2.3 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC Torsin PF06309.11 AFI84345.1 - 0.13 12.4 0.3 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Torsin CTP_synth_N PF06418.14 AFI84346.1 - 3.5e-126 419.9 0.1 4.6e-126 419.5 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AFI84346.1 - 1.3e-56 191.4 0.0 2.1e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AFI84346.1 - 1.3e-05 25.1 0.0 0.057 13.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 CbiA PF01656.23 AFI84346.1 - 0.00018 21.5 0.0 0.00035 20.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DAHP_synth_1 PF00793.20 AFI84347.1 - 1.8e-69 233.7 0.0 2.2e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Enolase_C PF00113.22 AFI84348.1 - 7.7e-134 445.6 0.3 9.7e-134 445.2 0.3 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AFI84348.1 - 9.5e-57 190.8 0.2 1.7e-56 190.0 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AFI84348.1 - 4.8e-05 23.0 0.1 7.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AFI84348.1 - 0.014 14.5 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus CwsA PF10814.8 AFI84348.1 - 0.14 12.3 1.4 0.37 11.0 1.4 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DivIC PF04977.15 AFI84349.1 - 3.5e-21 74.8 0.0 4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.15 AFI84349.1 - 0.025 14.7 1.0 0.033 14.3 1.0 1.2 1 0 0 1 1 1 0 Basic region leucine zipper DUF2205 PF10224.9 AFI84349.1 - 0.04 13.9 0.9 0.11 12.5 0.7 1.7 1 1 1 2 2 2 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 AFI84349.1 - 0.067 13.2 1.7 0.087 12.8 1.7 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IspD PF01128.19 AFI84350.1 - 3.5e-70 236.2 0.0 3.9e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AFI84350.1 - 9.6e-09 35.8 0.0 1.7e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AFI84350.1 - 0.0089 16.0 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase YgbB PF02542.16 AFI84351.1 - 3.2e-65 219.2 0.2 3.5e-65 219.0 0.2 1.0 1 0 0 1 1 1 1 YgbB family TruD PF01142.18 AFI84352.1 - 1.1e-64 218.8 0.0 3.7e-39 134.7 0.0 2.0 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF1223 PF06764.11 AFI84353.1 - 4.7e-48 163.9 0.0 5.5e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Omp28 PF11551.8 AFI84353.1 - 0.00049 20.0 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Outer membrane protein Omp28 TP_methylase PF00590.20 AFI84354.1 - 8.6e-53 179.4 0.2 2e-52 178.2 0.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 AFI84354.1 - 4.6e-32 110.6 0.3 1.3e-31 109.1 0.1 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AFI84354.1 - 4.6e-18 64.7 0.1 2e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 AFI84354.1 - 3.7e-07 29.5 0.6 7.1e-07 28.6 0.6 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 AFI84354.1 - 0.00022 21.3 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 AFI84354.1 - 0.041 13.1 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AFI84354.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AFI84354.1 - 0.15 12.4 1.1 1.8 8.8 1.1 2.4 1 1 0 1 1 1 0 TrkA-N domain TonB_dep_Rec PF00593.24 AFI84355.1 - 3e-41 142.8 38.3 7.7e-41 141.4 37.9 1.8 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI84355.1 - 1.1e-11 45.3 0.6 2.9e-11 43.9 0.6 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain BBP2_2 PF10082.9 AFI84355.1 - 4.8e-05 22.4 0.6 0.00047 19.1 0.1 2.5 2 1 0 2 2 2 1 Putative beta-barrel porin 2 OMP_b-brl PF13505.6 AFI84355.1 - 9.7 6.3 29.5 0.12 12.5 4.1 3.9 3 1 2 5 5 5 0 Outer membrane protein beta-barrel domain QRPTase_C PF01729.19 AFI84356.1 - 1.6e-55 187.4 0.6 2.2e-55 187.0 0.6 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AFI84356.1 - 2.3e-27 94.9 0.0 1.6e-25 88.9 0.0 2.3 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.20 AFI84356.1 - 0.0044 16.4 0.1 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 LysR substrate binding domain Ribul_P_3_epim PF00834.19 AFI84356.1 - 0.027 13.9 0.2 0.054 12.9 0.1 1.5 1 1 0 1 1 1 0 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 AFI84356.1 - 0.085 12.2 1.3 0.43 9.9 1.3 2.0 1 1 0 1 1 1 0 Thiamine monophosphate synthase Amidase_2 PF01510.25 AFI84357.1 - 1.6e-26 93.2 0.0 2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase FKBP_C PF00254.28 AFI84358.1 - 3.9e-28 97.6 0.3 7.2e-27 93.5 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AFI84358.1 - 3.5e-24 85.6 10.8 5.5e-24 85.0 10.8 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4827 PF16109.5 AFI84358.1 - 0.0089 16.0 1.1 0.24 11.4 0.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4827) TERB2 PF15101.6 AFI84358.1 - 0.015 15.4 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4483 PF14825.6 AFI84358.1 - 0.015 15.1 1.0 0.024 14.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) Pal1 PF08316.11 AFI84358.1 - 0.023 15.5 1.1 0.038 14.8 1.1 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Rrf2 PF02082.20 AFI84359.1 - 5.8e-19 68.2 0.2 9e-19 67.6 0.2 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_IclR PF09339.10 AFI84359.1 - 0.00068 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HrcA_DNA-bdg PF03444.15 AFI84359.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF2250 PF10007.9 AFI84359.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) MarR_2 PF12802.7 AFI84359.1 - 0.15 11.9 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 MarR family UPF0051 PF01458.17 AFI84360.1 - 3.3e-67 226.4 0.1 4.2e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) CHIPS PF11434.8 AFI84360.1 - 0.083 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS ABC_tran PF00005.27 AFI84361.1 - 3.7e-22 79.3 0.0 5.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AFI84361.1 - 3.9e-05 23.2 0.7 0.17 11.3 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AFI84361.1 - 0.00025 21.0 0.1 0.00042 20.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 AFI84361.1 - 0.0021 17.9 1.0 0.22 11.3 0.2 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AFI84361.1 - 0.0033 17.2 0.1 0.007 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AFI84361.1 - 0.0051 17.3 0.3 0.01 16.4 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AFI84361.1 - 0.0083 16.7 0.1 0.015 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AFI84361.1 - 0.0097 16.0 0.3 0.018 15.1 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_13 PF13166.6 AFI84361.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 AFI84361.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AFI84361.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 1 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 AFI84361.1 - 0.022 15.0 0.0 0.089 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AFI84361.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AFI84361.1 - 0.085 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 AFI84361.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain UPF0051 PF01458.17 AFI84362.1 - 1.8e-77 259.9 4.8 2.5e-77 259.4 4.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Aminotran_5 PF00266.19 AFI84363.1 - 9.7e-150 498.6 0.8 1.1e-149 498.4 0.8 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AFI84363.1 - 7.3e-10 38.5 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AFI84363.1 - 0.00051 18.7 0.2 0.0011 17.5 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AFI84363.1 - 0.0072 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AFI84363.1 - 0.0083 15.4 0.2 0.0098 15.2 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3235 PF11574.8 AFI84363.1 - 0.15 13.0 1.1 4.7 8.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) NifU_N PF01592.16 AFI84364.1 - 1.6e-26 92.9 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain CO_deh_flav_C PF03450.17 AFI84364.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain FeS_assembly_P PF01883.19 AFI84365.1 - 2.3e-22 78.9 0.1 2.9e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Wzy_C_2 PF11846.8 AFI84366.1 - 2.9e-29 102.3 5.6 2.9e-29 102.3 5.6 3.5 4 1 1 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal Wzy_C PF04932.15 AFI84366.1 - 1.7e-15 57.0 14.6 1.7e-15 57.0 14.6 4.7 2 1 1 3 3 3 1 O-Antigen ligase PglL_A PF15864.5 AFI84366.1 - 1.1e-05 25.0 4.7 1.1e-05 25.0 4.7 3.3 2 0 0 2 2 2 1 Protein glycosylation ligase Imm64 PF15600.6 AFI84367.1 - 0.0029 17.3 0.0 0.003 17.3 0.0 1.0 1 0 0 1 1 1 1 Immunity protein 64 N_methyl PF07963.12 AFI84368.1 - 1.3e-09 37.2 1.6 2.4e-09 36.3 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif CobS_N PF12556.8 AFI84369.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal N_methyl PF07963.12 AFI84370.1 - 1.4e-05 24.4 3.0 2.5e-05 23.6 3.0 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSG PF08334.11 AFI84370.1 - 0.023 14.8 0.1 2.3 8.3 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G MiaE_2 PF13794.6 AFI84370.1 - 0.087 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like N_methyl PF07963.12 AFI84371.1 - 1.9e-06 27.2 1.8 4.2e-06 26.1 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF2570 PF10828.8 AFI84372.1 - 0.11 12.3 5.7 1 9.2 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) CLZ PF16526.5 AFI84372.1 - 0.93 9.9 5.2 2 8.8 5.2 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 AFI84373.1 - 0.00038 20.1 6.4 0.0011 18.7 0.2 2.4 2 0 0 2 2 2 1 Septum formation initiator T2SSM PF04612.12 AFI84373.1 - 0.00053 20.1 6.6 0.0024 18.0 0.3 2.4 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein M IL34 PF15036.6 AFI84373.1 - 0.046 13.8 1.0 1 9.4 0.6 2.6 1 1 1 2 2 2 0 Interleukin 34 SLATT_2 PF18183.1 AFI84373.1 - 0.059 13.2 0.0 0.092 12.5 0.0 1.3 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 DUF4140 PF13600.6 AFI84373.1 - 0.16 12.5 5.4 0.37 11.3 3.7 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 AFI84373.1 - 0.22 11.1 1.1 0.42 10.1 1.1 1.5 1 0 0 1 1 1 0 fzo-like conserved region CCDC-167 PF15188.6 AFI84373.1 - 0.87 10.0 8.1 16 5.9 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 T2SSE PF00437.20 AFI84374.1 - 7.2e-73 245.0 0.1 1.1e-72 244.4 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AFI84374.1 - 2.1e-12 47.2 0.5 5e-12 46.0 0.5 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_16 PF13191.6 AFI84374.1 - 0.00026 21.4 0.0 0.00078 19.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 AFI84374.1 - 0.00041 20.0 0.1 0.0012 18.5 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AFI84374.1 - 0.016 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AFI84374.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AFI84374.1 - 0.021 15.3 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFI84374.1 - 0.027 15.0 0.0 0.44 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AFI84374.1 - 0.035 13.6 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 AFI84374.1 - 0.041 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 AFI84374.1 - 0.05 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AFI84374.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AFI84374.1 - 0.072 13.0 0.1 0.31 11.0 0.0 2.1 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.27 AFI84374.1 - 0.085 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SSF PF00482.23 AFI84375.1 - 2.6e-52 176.0 16.2 1.8e-28 99.0 5.9 2.4 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F TMP_2 PF06791.13 AFI84375.1 - 0.14 11.8 3.1 0.89 9.2 0.2 2.6 2 1 0 2 2 2 0 Prophage tail length tape measure protein DUF2207 PF09972.9 AFI84375.1 - 0.32 9.7 3.6 0.099 11.4 0.8 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Secretin PF00263.21 AFI84377.1 - 3.1e-38 131.1 3.6 3.1e-38 131.1 3.6 2.6 3 0 0 3 3 3 1 Bacterial type II and III secretion system protein DUF3438 PF11920.8 AFI84377.1 - 2.6e-11 43.3 0.0 4.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3438) DUF4974 PF16344.5 AFI84377.1 - 1.7e-05 24.7 0.2 0.00014 21.8 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4974) Secretin_N PF03958.17 AFI84377.1 - 0.0075 16.6 16.5 0.051 14.0 12.6 3.7 3 1 0 3 3 3 1 Bacterial type II/III secretion system short domain Adenine_deam_C PF13382.6 AFI84377.1 - 0.0087 15.4 0.2 0.018 14.4 0.2 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Lum_binding PF00677.17 AFI84377.1 - 0.093 12.7 0.7 0.31 11.0 0.7 1.9 1 0 0 1 1 1 0 Lumazine binding domain Pom PF17251.2 AFI84378.1 - 3.2e-103 344.9 3.3 3.7e-103 344.7 3.3 1.0 1 0 0 1 1 1 1 Protochlamydia outer membrane protein HisKA_3 PF07730.13 AFI84379.1 - 1.7e-11 44.4 0.3 3.2e-10 40.4 0.2 2.8 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AFI84379.1 - 3.7e-08 33.8 0.5 1.8e-06 28.4 0.5 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LapD_MoxY_N PF16448.5 AFI84379.1 - 6.1e-08 32.6 0.7 1.5e-07 31.3 0.7 1.7 1 0 0 1 1 1 1 LapD/MoxY periplasmic domain HATPase_c_2 PF13581.6 AFI84379.1 - 0.00034 20.5 0.0 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HAMP PF00672.25 AFI84379.1 - 0.001 19.4 0.8 0.036 14.5 0.0 3.0 2 0 0 2 2 2 1 HAMP domain DNA_repr_REX1B PF14966.6 AFI84379.1 - 0.071 13.8 3.1 0.096 13.4 0.6 2.4 2 1 1 3 3 3 0 DNA repair REX1-B Lyase_8_N PF08124.11 AFI84379.1 - 0.11 11.4 0.5 0.49 9.3 0.2 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Response_reg PF00072.24 AFI84380.1 - 3.1e-25 88.5 0.3 6.6e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AFI84380.1 - 9.5e-13 47.5 0.0 1.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI84380.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 AFI84380.1 - 0.18 11.7 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HSP20 PF00011.21 AFI84381.1 - 2e-24 85.7 0.2 2.4e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AFI84381.1 - 5.2e-09 35.5 0.2 2.1e-08 33.6 0.0 2.0 2 1 0 2 2 2 1 HSP20-like domain found in ArsA BON PF04972.17 AFI84381.1 - 0.011 16.0 0.5 0.43 10.9 0.1 2.8 2 1 1 3 3 3 0 BON domain PepSY PF03413.19 AFI84382.1 - 2.4e-17 63.2 2.1 3.2e-10 40.4 2.1 2.2 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 AFI84382.1 - 0.00066 19.6 4.3 0.41 10.7 0.6 2.6 2 1 0 2 2 2 2 Peptidase propeptide and YPEB domain GlgS PF08971.11 AFI84382.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Glycogen synthesis protein DUF3040 PF11239.8 AFI84382.1 - 0.16 12.2 0.0 0.58 10.5 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) tRNA-synt_1g PF09334.11 AFI84383.1 - 1.6e-158 527.6 0.0 2e-158 527.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 AFI84383.1 - 6e-24 84.0 0.0 1.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 AFI84383.1 - 2.4e-15 55.8 0.2 5.1e-09 34.9 0.0 2.8 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AFI84383.1 - 8e-12 45.1 0.2 4.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AFI84383.1 - 1e-06 27.9 0.1 0.00037 19.5 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 AFI84383.1 - 6.3e-06 26.2 0.9 3.1e-05 24.0 0.3 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1b PF00579.25 AFI84383.1 - 0.071 12.4 0.0 5.9 6.1 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) TPR_14 PF13428.6 AFI84384.1 - 0.058 14.2 1.9 2.9 8.9 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84384.1 - 0.068 13.0 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Sdh_cyt PF01127.22 AFI84385.1 - 0.00019 21.4 22.1 0.0014 18.7 2.3 2.1 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ninjurin PF04923.12 AFI84385.1 - 0.032 14.2 1.0 0.032 14.2 1.0 2.4 2 2 0 2 2 2 0 Ninjurin CitMHS PF03600.16 AFI84385.1 - 0.61 9.2 11.5 0.75 8.9 11.5 1.2 1 0 0 1 1 1 0 Citrate transporter FAD_binding_2 PF00890.24 AFI84386.1 - 7.4e-50 170.2 0.6 1.2e-49 169.5 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 AFI84386.1 - 8.8e-33 113.0 0.0 1.4e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 AFI84386.1 - 9.4e-07 28.7 0.2 6.5e-06 26.0 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AFI84386.1 - 1.8e-06 27.4 0.5 0.00021 20.6 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AFI84386.1 - 4.1e-05 22.9 0.6 0.00048 19.3 0.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AFI84386.1 - 0.0017 18.5 0.2 0.01 16.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AFI84386.1 - 0.0084 15.4 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AFI84386.1 - 0.025 13.3 0.1 0.094 11.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 AFI84386.1 - 0.031 13.5 0.1 0.058 12.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 AFI84386.1 - 0.047 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AFI84386.1 - 0.23 11.3 0.1 0.5 10.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fer2_3 PF13085.6 AFI84387.1 - 1.3e-24 86.3 0.3 3.8e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 AFI84387.1 - 1e-08 35.6 2.2 1e-08 35.6 2.2 2.2 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI84387.1 - 2.6e-08 34.2 2.8 2.6e-08 34.2 2.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI84387.1 - 3.8e-08 33.3 3.0 3.8e-08 33.3 3.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AFI84387.1 - 5.9e-07 29.9 14.8 6.6e-06 26.6 6.0 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 AFI84387.1 - 3.1e-06 26.7 3.5 3.1e-06 26.7 3.5 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 AFI84387.1 - 6.4e-06 26.0 3.2 6.4e-06 26.0 3.2 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 AFI84387.1 - 3.1e-05 24.1 0.4 0.022 14.9 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI84387.1 - 3.2e-05 23.8 4.0 3.2e-05 23.8 4.0 3.2 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_9 PF13187.6 AFI84387.1 - 3.7e-05 23.8 10.2 0.00011 22.3 0.2 3.0 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI84387.1 - 0.00015 22.0 1.1 0.00015 22.0 1.1 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer2 PF00111.27 AFI84387.1 - 0.0025 17.7 1.1 0.0025 17.7 1.1 2.3 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.6 AFI84387.1 - 0.0043 17.9 18.9 0.017 16.0 8.3 2.7 2 1 2 4 4 4 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 AFI84387.1 - 0.0047 17.8 5.6 0.0047 17.8 5.6 3.2 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_15 PF13459.6 AFI84387.1 - 0.0071 17.1 0.3 0.0071 17.1 0.3 2.1 2 0 0 2 2 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 AFI84387.1 - 0.0092 16.1 6.2 0.0092 16.1 6.2 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 AFI84387.1 - 0.013 16.3 0.2 0.013 16.3 0.2 2.8 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AFI84387.1 - 0.027 15.0 3.7 0.027 15.0 3.7 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Ribosomal_S27e PF01667.17 AFI84387.1 - 0.22 11.2 0.2 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 DUF389 PF04087.14 AFI84388.1 - 2.4e-36 124.9 13.7 2.4e-36 124.9 13.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF389) S6PP PF05116.13 AFI84390.1 - 3e-78 262.8 0.0 5.1e-78 262.0 0.0 1.4 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Glycos_transf_1 PF00534.20 AFI84390.1 - 8.5e-26 90.5 0.0 2.3e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.19 AFI84390.1 - 2e-17 62.7 0.2 6.3e-17 61.1 0.1 1.8 2 1 0 2 2 2 1 Sucrose synthase Glyco_transf_4 PF13439.6 AFI84390.1 - 2e-13 50.7 0.0 5.6e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI84390.1 - 8.9e-13 49.0 0.5 5.5e-12 46.4 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Hydrolase_3 PF08282.12 AFI84390.1 - 9.1e-13 48.5 0.0 2.3e-07 30.8 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.6 AFI84390.1 - 4.1e-12 46.7 0.0 1.9e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI84390.1 - 1.4e-06 28.6 0.0 1.4e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AFI84390.1 - 0.0067 16.5 0.1 0.035 14.1 0.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like S6PP PF05116.13 AFI84391.1 - 2e-49 168.3 0.2 2.8e-49 167.9 0.2 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 AFI84391.1 - 4.6e-17 62.6 0.0 2.7e-12 47.0 0.2 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI84391.1 - 0.14 12.6 0.0 20 5.5 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2844 PF11005.8 AFI84391.1 - 0.14 12.2 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) PfkB PF00294.24 AFI84392.1 - 3.6e-37 128.3 0.0 4.3e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Exo_endo_phos_2 PF14529.6 AFI84392.1 - 0.015 15.1 0.1 0.043 13.6 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Alpha-amylase PF00128.24 AFI84393.1 - 3.5e-43 148.4 0.1 7.1e-39 134.3 0.1 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 AFI84393.1 - 8.7e-08 31.7 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 AFI84393.1 - 6.1e-05 23.1 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF393 PF04134.12 AFI84394.1 - 2e-20 74.2 0.2 2.4e-20 73.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF836 PF05768.14 AFI84394.1 - 0.043 14.2 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.6 AFI84394.1 - 0.25 11.1 0.0 0.33 10.7 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein FAD_binding_7 PF03441.14 AFI84395.1 - 1.1e-42 145.8 2.5 1.8e-42 145.1 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AFI84395.1 - 1.8e-30 106.1 0.1 2.7e-30 105.5 0.1 1.2 1 0 0 1 1 1 1 DNA photolyase SET_assoc PF11767.8 AFI84395.1 - 0.15 11.7 0.0 0.47 10.1 0.0 1.8 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Na_Ca_ex PF01699.24 AFI84397.1 - 1.8e-53 180.5 35.0 2.6e-30 105.4 14.3 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HisG PF01634.18 AFI84397.1 - 0.035 14.1 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 ATP phosphoribosyltransferase GGDEF PF00990.21 AFI84398.1 - 1e-41 142.4 1.9 1.2e-41 142.2 0.8 1.6 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AFI84398.1 - 8.1e-22 77.3 0.4 1.6e-21 76.3 0.4 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AFI84398.1 - 0.00013 21.9 0.3 0.00041 20.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold DUF3847 PF12958.7 AFI84398.1 - 0.00031 20.8 2.1 0.0008 19.5 2.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3847) PAS_9 PF13426.7 AFI84398.1 - 0.00077 19.7 0.0 0.0025 18.0 0.0 1.9 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 AFI84398.1 - 0.0022 18.3 0.7 0.072 13.4 0.0 2.4 2 0 0 2 2 2 1 GGDEF-like domain PAS_11 PF14598.6 AFI84398.1 - 0.0035 17.4 0.2 0.01 16.0 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AFI84398.1 - 0.012 15.6 0.1 0.081 13.0 0.0 2.3 2 0 0 2 2 2 0 PAS domain Mut7-C PF01927.16 AFI84398.1 - 0.29 11.2 1.8 3.3 7.8 0.2 2.8 2 1 0 2 2 2 0 Mut7-C RNAse domain DivIC PF04977.15 AFI84398.1 - 0.63 9.8 3.5 2.4 8.0 0.2 2.7 1 1 1 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.11 AFI84398.1 - 1.2 9.0 5.7 0.17 11.7 1.3 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Radical_SAM PF04055.21 AFI84399.1 - 7.5e-30 104.5 0.0 5.6e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 AFI84399.1 - 5.7e-20 71.2 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM_2 PF18693.1 AFI84399.1 - 5.4e-19 68.1 1.7 1.1e-18 67.1 1.7 1.6 1 0 0 1 1 1 1 TRAM domain CLP1_P PF16575.5 AFI84399.1 - 0.069 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Hydrolase_like PF13242.6 AFI84400.1 - 2.2e-17 62.8 0.0 4.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AFI84400.1 - 5.3e-17 61.8 0.0 1.3e-15 57.3 0.0 2.7 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AFI84400.1 - 1.6e-06 28.3 0.0 2.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI84400.1 - 3.1e-05 24.4 0.9 0.004 17.5 0.2 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Memo PF01875.17 AFI84401.1 - 1.6e-52 178.4 0.2 1.9e-52 178.1 0.2 1.1 1 0 0 1 1 1 1 Memo-like protein Putative_PNPOx PF01243.20 AFI84402.1 - 8.2e-16 58.0 0.0 1.3e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LysR_substrate PF03466.20 AFI84403.1 - 6.3e-40 136.8 0.1 1.2e-39 135.9 0.0 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AFI84403.1 - 7.7e-19 67.4 2.0 7.7e-19 67.4 2.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AFI84403.1 - 0.08 12.8 1.9 0.1 12.4 0.4 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain NPR1_like_C PF12313.8 AFI84403.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Flavodoxin_2 PF02525.17 AFI84404.1 - 2.3e-39 135.2 0.0 2.8e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AFI84404.1 - 7.8e-14 51.7 0.0 9.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase BRCT PF00533.26 AFI84404.1 - 0.084 13.3 0.0 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Pirin PF02678.16 AFI84405.1 - 3e-37 126.9 0.0 6e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AFI84405.1 - 1.1e-30 106.1 0.1 1.9e-29 102.0 0.0 2.4 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 AFI84405.1 - 0.024 14.4 0.5 5.8 6.7 0.0 2.8 2 1 0 2 2 2 0 Cupin domain Pirin_C_2 PF17954.1 AFI84405.1 - 0.052 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain NTase_sub_bind PF08780.11 AFI84405.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like BON PF04972.17 AFI84406.1 - 2.5e-21 75.7 4.7 3.9e-21 75.1 4.7 1.3 1 0 0 1 1 1 1 BON domain HTH_Crp_2 PF13545.6 AFI84407.1 - 1.8e-14 53.5 1.4 2.5e-14 53.0 0.7 1.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Response_reg PF00072.24 AFI84408.1 - 1.8e-23 82.8 0.0 3.3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84408.1 - 3.7e-22 78.2 0.1 6.5e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AFI84408.1 - 0.0025 18.2 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ GerE PF00196.19 AFI84408.1 - 0.012 15.1 0.1 6.2 6.5 0.3 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_11 PF08279.12 AFI84408.1 - 0.013 15.4 0.5 0.068 13.1 0.2 2.3 2 1 0 2 2 2 0 HTH domain OKR_DC_1_N PF03709.15 AFI84408.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain HATPase_c PF02518.26 AFI84409.1 - 4.4e-15 56.2 0.0 8.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84409.1 - 3e-10 40.0 0.5 3e-10 40.0 0.5 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain 2CSK_N PF08521.10 AFI84409.1 - 9.1e-09 35.5 0.5 5.2e-08 33.1 0.3 2.2 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HATPase_c_2 PF13581.6 AFI84409.1 - 4.2e-06 26.7 0.1 8.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AFI84409.1 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 GHKL domain HAMP PF00672.25 AFI84409.1 - 0.0098 16.3 0.2 0.049 14.0 0.2 2.3 1 0 0 1 1 1 1 HAMP domain AlaDh_PNT_C PF01262.21 AFI84410.1 - 1.7e-73 246.5 1.8 2.3e-73 246.0 1.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AFI84410.1 - 8.8e-45 152.3 0.0 1.6e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 AFI84410.1 - 4.3e-06 26.2 0.1 7.9e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AFI84410.1 - 4.3e-05 23.7 0.5 0.0001 22.5 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AFI84410.1 - 8.5e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 AFI84410.1 - 0.00031 21.3 0.1 0.0006 20.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AFI84410.1 - 0.00068 19.0 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AFI84410.1 - 0.00076 19.4 0.2 0.0023 17.8 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AFI84410.1 - 0.0033 17.8 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 AFI84410.1 - 0.0075 15.9 0.5 0.018 14.7 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 AFI84410.1 - 0.01 16.1 0.1 0.025 14.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 AFI84410.1 - 0.034 13.7 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 AFI84410.1 - 0.066 13.8 0.4 0.27 11.8 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 AFI84410.1 - 0.41 10.0 1.7 0.93 8.8 1.0 1.9 1 1 1 2 2 2 0 ThiF family YdjM PF04307.14 AFI84411.1 - 0.00011 21.6 0.7 0.00016 21.0 0.7 1.3 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase TPR_1 PF00515.28 AFI84413.1 - 2.8e-52 172.5 21.6 4.2e-09 35.8 1.9 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84413.1 - 8.8e-49 159.7 23.0 3.4e-08 33.0 0.0 8.4 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 AFI84413.1 - 1.5e-48 162.2 25.5 3.7e-11 42.5 1.0 7.0 1 1 6 7 7 7 6 TPR repeat TPR_8 PF13181.6 AFI84413.1 - 5.4e-41 135.4 13.0 2.6e-07 30.3 1.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 AFI84413.1 - 2.1e-37 124.8 16.2 0.00013 22.1 0.0 7.4 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.6 AFI84413.1 - 2.6e-36 124.0 30.3 9.6e-12 45.4 2.2 5.5 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 AFI84413.1 - 1.9e-35 121.0 25.2 4.4e-10 39.7 1.3 6.4 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 AFI84413.1 - 4.2e-30 101.6 12.3 9.6e-05 22.1 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 AFI84413.1 - 6.2e-29 98.2 7.7 0.00059 20.5 0.1 7.8 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 AFI84413.1 - 1e-27 96.4 16.3 3.8e-07 30.5 2.3 5.8 4 1 3 7 7 6 5 Tetratricopeptide repeat 2OG-FeII_Oxy_5 PF13759.6 AFI84413.1 - 1.3e-25 89.8 0.1 2.5e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase TPR_10 PF13374.6 AFI84413.1 - 1.1e-20 72.7 21.0 0.0011 18.8 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 AFI84413.1 - 3.2e-19 68.2 19.2 0.00032 21.1 1.6 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 AFI84413.1 - 2.1e-11 43.8 3.2 0.018 15.2 0.0 4.4 2 1 3 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI84413.1 - 2.3e-11 43.7 12.2 2.6e-05 24.4 0.8 4.5 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 AFI84413.1 - 2.4e-11 43.4 4.8 3.2e-11 43.0 3.5 1.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AFI84413.1 - 2.7e-08 33.6 1.9 0.0036 16.7 0.1 3.4 2 1 1 3 3 3 2 MalT-like TPR region TPR_3 PF07720.12 AFI84413.1 - 6.7e-08 32.4 21.9 0.016 15.2 2.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 AFI84413.1 - 2e-07 31.0 0.2 2.9 8.8 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AFI84413.1 - 2e-05 24.2 0.0 0.04 13.3 0.0 3.4 1 1 1 4 4 4 1 Coatomer epsilon subunit NARP1 PF12569.8 AFI84413.1 - 2.4e-05 23.5 0.4 0.19 10.6 0.0 3.0 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 AFI84413.1 - 0.00056 19.7 9.2 0.1 12.3 3.2 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 AFI84413.1 - 0.00074 19.5 0.6 1.4 8.8 0.1 2.7 1 1 1 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 AFI84413.1 - 0.00077 19.9 4.5 0.38 11.2 0.3 3.8 2 1 2 4 4 4 1 Bacterial transcriptional activator domain DUF3856 PF12968.7 AFI84413.1 - 0.00081 19.5 1.1 2.9 7.9 0.1 4.9 1 1 2 3 3 3 1 Domain of Unknown Function (DUF3856) DUF627 PF04781.12 AFI84413.1 - 0.00081 19.4 0.2 0.92 9.5 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF627) 2OG-FeII_Oxy_3 PF13640.6 AFI84413.1 - 0.00083 20.2 0.0 0.002 19.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAT PF02259.23 AFI84413.1 - 0.0012 18.2 0.0 0.52 9.5 0.0 3.2 1 1 1 2 2 2 1 FAT domain TPR_5 PF12688.7 AFI84413.1 - 0.01 16.0 0.5 0.081 13.2 0.3 2.5 1 1 1 2 2 2 0 Tetratrico peptide repeat SHNi-TPR PF10516.9 AFI84413.1 - 0.017 14.5 4.3 0.84 9.1 0.0 4.7 4 1 1 5 5 5 0 SHNi-TPR HrpB1_HrpK PF09613.10 AFI84413.1 - 0.023 14.4 0.0 8.4 6.1 0.0 3.2 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF1402 PF07182.11 AFI84413.1 - 0.027 13.5 0.1 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1402) MIT PF04212.18 AFI84413.1 - 0.032 14.3 15.8 4.2 7.5 1.8 6.7 6 1 2 8 8 7 0 MIT (microtubule interacting and transport) domain DUF3808 PF10300.9 AFI84413.1 - 0.033 12.9 0.0 0.16 10.7 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3808) TOM20_plant PF06552.12 AFI84413.1 - 0.044 13.5 0.4 1.5 8.6 0.0 3.2 1 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 2OG-FeII_Oxy PF03171.20 AFI84413.1 - 0.16 12.5 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Exonuc_VII_S PF02609.16 AFI84413.1 - 2.6 8.2 8.7 53 4.0 0.0 5.4 7 0 0 7 7 4 0 Exonuclease VII small subunit Sel1 PF08238.12 AFI84413.1 - 5.6 7.8 11.2 11 6.9 2.4 4.1 3 2 0 3 3 2 0 Sel1 repeat AhpC-TSA PF00578.21 AFI84414.1 - 1.8e-35 121.5 0.0 2.1e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AFI84414.1 - 2.3e-16 59.8 0.0 2.6e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 AFI84414.1 - 3.9e-05 23.3 0.0 4.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 AFI84414.1 - 0.00029 20.9 0.0 0.0055 16.8 0.0 2.0 1 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme DHDPS PF00701.22 AFI84415.1 - 1.2e-107 359.0 0.0 1.3e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CutC PF03932.14 AFI84415.1 - 0.009 15.5 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 CutC family Lipoprotein_18 PF06804.11 AFI84416.1 - 2e-25 89.5 5.7 5e-24 84.9 5.7 2.6 1 1 0 1 1 1 1 NlpB/DapX lipoprotein DUF1998 PF09369.10 AFI84416.1 - 0.12 13.2 0.0 11 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) Lactamase_B_2 PF12706.7 AFI84417.1 - 2.2e-24 86.1 0.3 2.9e-24 85.7 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AFI84417.1 - 9.9e-19 68.1 0.2 1.5e-18 67.5 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 AFI84417.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AFI84417.1 - 0.00035 20.5 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 AFI84417.1 - 0.012 14.7 0.0 0.029 13.5 0.0 1.6 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II OKR_DC_1_N PF03709.15 AFI84417.1 - 0.021 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain SAICAR_synt PF01259.18 AFI84418.1 - 8.2e-66 222.2 0.0 9.3e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Wzy_C PF04932.15 AFI84419.1 - 4.6e-16 58.8 2.6 4.6e-16 58.8 2.6 3.9 1 1 1 3 3 3 1 O-Antigen ligase Wzy_C_2 PF11846.8 AFI84419.1 - 1.1e-12 48.2 4.5 1.1e-12 48.2 4.5 3.0 3 1 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal PglL_A PF15864.5 AFI84419.1 - 7e-07 28.8 0.3 4.8e-06 26.2 0.3 2.7 1 0 0 1 1 1 1 Protein glycosylation ligase UTP15_C PF09384.10 AFI84419.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal N_methyl PF07963.12 AFI84420.1 - 2.1e-11 42.8 2.5 4.1e-11 41.9 2.5 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Pilin PF00114.19 AFI84420.1 - 0.00026 21.9 0.4 0.00036 21.4 0.4 1.2 1 0 0 1 1 1 1 Pilin (bacterial filament) Zn_protease PF05618.11 AFI84421.1 - 1.6e-36 125.3 0.0 1.8e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependant zinc protease gag-asp_proteas PF13975.6 AFI84421.1 - 0.08 13.5 0.0 6.3 7.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RimK PF08443.11 AFI84422.1 - 2.9e-67 225.9 0.0 3.8e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AFI84422.1 - 2.6e-47 159.1 0.1 5e-47 158.2 0.1 1.5 1 0 0 1 1 1 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AFI84422.1 - 1.6e-15 56.9 0.2 2.5e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AFI84422.1 - 4.7e-08 32.6 0.0 0.0047 16.2 0.0 3.1 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AFI84422.1 - 2.4e-07 30.9 0.0 4.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AFI84422.1 - 0.0023 17.5 0.4 0.032 13.8 0.4 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus R2K_3 PF14243.6 AFI84422.1 - 0.003 17.6 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 ATPgrasp_YheCD PF14398.6 AFI84422.1 - 0.0045 16.3 0.0 0.44 9.7 0.0 2.9 1 1 2 3 3 3 1 YheC/D like ATP-grasp TTL PF03133.15 AFI84422.1 - 0.27 10.3 0.0 0.85 8.7 0.0 1.9 2 1 1 3 3 3 0 Tubulin-tyrosine ligase family AstE_AspA PF04952.14 AFI84423.1 - 2.7e-56 190.8 0.0 3.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 AFI84423.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Orn_Arg_deC_N PF02784.16 AFI84424.1 - 4.2e-35 121.3 0.0 6.2e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 AFI84424.1 - 7.5e-24 83.8 1.3 2.2e-23 82.3 0.4 2.2 2 0 0 2 2 2 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 AFI84424.1 - 1.1e-14 54.7 0.0 2.8e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension Sacchrp_dh_C PF16653.5 AFI84425.1 - 6.4e-38 131.4 0.0 8.5e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 AFI84425.1 - 1.3e-35 122.5 0.0 2.1e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AFI84425.1 - 0.0091 16.6 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AFI84425.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 AFI84425.1 - 0.025 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GARS_N PF02844.15 AFI84425.1 - 0.071 13.9 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Polysacc_synt_2 PF02719.15 AFI84425.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.22 AFI84425.1 - 0.093 13.6 0.0 0.17 12.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Orn_DAP_Arg_deC PF00278.22 AFI84426.1 - 2.7e-09 37.1 0.0 3e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Arginase PF00491.21 AFI84427.1 - 1.9e-61 208.0 0.0 2.3e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family SnoaL_2 PF12680.7 AFI84428.1 - 9.8e-18 64.7 0.1 1.1e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AFI84428.1 - 7.1e-13 48.5 0.1 7.9e-13 48.3 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 AFI84428.1 - 1.8e-06 28.3 0.1 2.5e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AFI84428.1 - 0.0002 21.6 0.1 0.00026 21.2 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 AFI84428.1 - 0.00081 20.0 0.0 0.00095 19.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 AFI84428.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF5335 PF17269.2 AFI84428.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Acetyltransf_1 PF00583.25 AFI84429.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AFI84429.1 - 0.0097 16.0 0.0 0.038 14.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CN_hydrolase PF00795.22 AFI84430.1 - 1.9e-20 73.3 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CsrA PF02599.16 AFI84430.1 - 0.18 11.8 0.0 0.44 10.5 0.0 1.6 2 0 0 2 2 2 0 Global regulator protein family ParA PF10609.9 AFI84431.1 - 1.1e-103 346.0 0.3 1.6e-103 345.4 0.3 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AFI84431.1 - 3.6e-14 52.9 0.0 2.4e-13 50.2 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AFI84431.1 - 1.1e-10 41.7 3.3 7.8e-09 35.7 1.3 2.5 2 1 0 2 2 2 1 AAA domain MipZ PF09140.11 AFI84431.1 - 5.6e-09 35.7 0.0 9.1e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AFI84431.1 - 3.3e-07 30.0 0.0 0.0007 19.1 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AFI84431.1 - 3.7e-05 23.1 3.0 0.0011 18.2 0.7 2.9 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.11 AFI84431.1 - 0.00028 20.3 0.1 0.0011 18.4 0.0 1.8 2 0 0 2 2 2 1 VirC1 protein FeS_assembly_P PF01883.19 AFI84431.1 - 0.0014 18.8 0.3 0.0046 17.1 0.3 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein AAA_26 PF13500.6 AFI84431.1 - 0.041 13.7 1.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AFI84431.1 - 0.048 13.2 0.1 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain dUTPase PF00692.19 AFI84432.1 - 7.5e-10 38.6 0.0 3.8e-09 36.3 0.0 1.8 1 1 1 2 2 2 1 dUTPase Flagellar_put PF12611.8 AFI84432.1 - 0.016 14.9 0.6 0.028 14.2 0.6 1.3 1 0 0 1 1 1 0 Putative flagellar WD40 PF00400.32 AFI84433.1 - 6.1e-13 49.0 4.7 2.1e-05 25.2 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 AFI84433.1 - 2.1e-08 34.3 0.0 1.4 9.3 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 AFI84433.1 - 0.001 19.0 0.3 0.027 14.3 0.0 2.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 AFI84433.1 - 0.024 13.3 1.2 0.66 8.6 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 AFI84433.1 - 0.073 12.4 0.2 11 5.3 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal CutA1 PF03091.15 AFI84434.1 - 0.0016 18.2 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF3458_C PF17432.2 AFI84435.1 - 1.7e-124 415.3 7.0 2.6e-124 414.8 7.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 AFI84435.1 - 1.6e-51 175.0 0.1 2.9e-51 174.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 AFI84435.1 - 1.1e-30 105.9 0.1 3e-30 104.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 AFI84435.1 - 6.3e-16 59.1 0.0 1.5e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 AFI84435.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 M61 glycyl aminopeptidase FliG_M PF14841.6 AFI84435.1 - 0.14 12.4 0.1 3.9 7.8 0.0 2.6 2 0 0 2 2 2 0 FliG middle domain HIT PF01230.23 AFI84436.1 - 2.3e-16 60.3 0.0 3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AFI84436.1 - 0.035 14.6 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding DUF2835 PF11197.8 AFI84437.1 - 2.5e-28 97.7 0.1 2.9e-28 97.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2835) DNA_gyraseA_C PF03989.13 AFI84437.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller RDD PF06271.12 AFI84438.1 - 1.9e-16 60.5 6.8 2.1e-16 60.4 6.8 1.0 1 0 0 1 1 1 1 RDD family DHHC PF01529.20 AFI84438.1 - 0.18 11.9 0.1 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase GATase_5 PF13507.6 AFI84439.1 - 1.3e-101 339.1 0.0 2e-101 338.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 AFI84439.1 - 5.2e-49 166.4 0.3 1.9e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 AFI84439.1 - 6.8e-36 122.8 0.0 1.1e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 AFI84439.1 - 2.9e-23 82.2 0.2 2.9e-22 78.9 0.1 2.4 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain Tegument_dsDNA PF12818.7 AFI84439.1 - 0.014 14.5 0.0 0.094 11.8 0.0 2.0 2 0 0 2 2 2 0 dsDNA viral tegument protein GGDEF PF00990.21 AFI84440.1 - 1.2e-33 116.2 0.1 3e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain 7TMR-DISM_7TM PF07695.11 AFI84440.1 - 0.00014 21.9 37.8 0.00024 21.1 37.8 1.3 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF3336 PF11815.8 AFI84440.1 - 0.53 10.0 2.4 0.99 9.1 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) DUF202 PF02656.15 AFI84440.1 - 9.9 6.7 17.5 0.73 10.3 2.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) GGDEF PF00990.21 AFI84441.1 - 9.9e-08 31.9 0.0 1.1e-07 31.8 0.0 1.0 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain 17kDa_Anti_2 PF16998.5 AFI84442.1 - 1.8e-09 37.5 0.8 2.1e-09 37.3 0.8 1.2 1 0 0 1 1 1 1 17 kDa outer membrane surface antigen Gly-zipper_Omp PF13488.6 AFI84442.1 - 1.3e-05 25.1 20.9 2.8e-05 24.0 20.9 1.6 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 AFI84442.1 - 1.6e-05 24.6 29.2 2.9e-05 23.8 29.2 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF5061 PF16587.5 AFI84442.1 - 0.0078 16.3 0.4 0.13 12.3 0.4 2.0 1 1 0 1 1 1 1 17 kDa common-antigen outer membrane protein TraT PF05818.12 AFI84442.1 - 0.054 13.2 5.0 0.073 12.7 5.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Peptidase_A8 PF01252.18 AFI84442.1 - 0.52 10.6 1.9 18 5.6 0.0 2.1 1 1 1 2 2 2 0 Signal peptidase (SPase) II EAL PF00563.20 AFI84443.1 - 3.4e-73 246.1 0.5 7.6e-73 244.9 0.0 1.9 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AFI84443.1 - 7.5e-53 178.6 0.1 2.2e-52 177.0 0.1 1.9 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AFI84443.1 - 1.5e-15 57.2 0.0 5e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AFI84443.1 - 5.3e-11 42.7 0.0 1.4e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain HAMP PF00672.25 AFI84443.1 - 1.2e-10 41.6 0.0 5.8e-10 39.4 0.0 2.3 1 0 0 1 1 1 1 HAMP domain PAS_4 PF08448.10 AFI84443.1 - 3.4e-07 30.5 0.2 2.1e-06 27.9 0.0 2.5 2 1 1 3 3 3 1 PAS fold PAS_8 PF13188.7 AFI84443.1 - 9.7e-07 28.7 0.1 0.00013 21.9 0.0 3.2 3 0 0 3 3 3 1 PAS domain NIT PF08376.10 AFI84443.1 - 1.4e-06 28.9 2.7 2.4e-06 28.2 0.9 2.1 1 1 1 2 2 2 1 Nitrate and nitrite sensing PAS_3 PF08447.12 AFI84443.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF423 PF04241.15 AFI84443.1 - 0.093 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF423) FAP206 PF12018.8 AFI84443.1 - 0.94 8.9 4.7 0.17 11.3 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function LysE PF01810.18 AFI84444.1 - 3.9e-22 78.7 16.3 5.1e-22 78.3 16.3 1.1 1 0 0 1 1 1 1 LysE type translocator MASE1 PF05231.14 AFI84445.1 - 2.1e-13 50.1 6.3 2.3e-13 49.9 6.3 1.0 1 0 0 1 1 1 1 MASE1 ABC_membrane_3 PF13748.6 AFI84445.1 - 0.035 13.3 0.2 0.046 12.9 0.2 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DPM3 PF08285.11 AFI84445.1 - 1.7 8.9 5.6 2.8 8.2 5.6 1.6 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) GGDEF PF00990.21 AFI84446.1 - 2e-47 161.0 1.9 6.1e-47 159.4 0.2 2.2 2 1 0 2 2 2 1 Diguanylate cyclase, GGDEF domain DUF4200 PF13863.6 AFI84446.1 - 0.034 14.5 4.5 0.071 13.5 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.15 AFI84446.1 - 4.3 7.2 9.9 0.1 12.4 1.9 2.5 3 1 1 4 4 4 0 Septum formation initiator ATP-grasp_4 PF13535.6 AFI84448.1 - 5.1e-06 26.2 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AFI84448.1 - 0.037 13.6 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GGDEF PF00990.21 AFI84449.1 - 6.8e-49 165.7 0.2 1.6e-48 164.5 0.2 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AFI84449.1 - 8e-19 68.4 0.9 1.9e-18 67.2 0.9 1.6 1 0 0 1 1 1 1 Cache domain GGDEF_2 PF17853.1 AFI84449.1 - 0.001 19.3 0.0 0.035 14.3 0.0 2.8 3 0 0 3 3 3 1 GGDEF-like domain PAS_4 PF08448.10 AFI84449.1 - 0.002 18.3 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold GCH_III PF05165.12 AFI84449.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase III sCache_3_2 PF17203.4 AFI84449.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Single cache domain 3 Sigma_reg_N PF13800.6 AFI84449.1 - 0.81 10.0 5.8 8.2 6.8 0.2 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal COX1 PF00115.20 AFI84450.1 - 1.4e-114 383.3 61.3 1.4e-114 383.3 61.3 1.3 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I CBS PF00571.28 AFI84452.1 - 2.3e-24 85.6 2.2 2.7e-11 43.7 0.1 2.1 2 0 0 2 2 2 2 CBS domain Acetyltransf_10 PF13673.7 AFI84452.1 - 0.0049 16.8 0.2 0.39 10.7 0.1 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain sCache_3_2 PF17203.4 AFI84452.1 - 0.022 14.9 0.1 0.062 13.4 0.1 1.9 1 1 0 1 1 1 0 Single cache domain 3 rhaM PF05336.13 AFI84452.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 L-rhamnose mutarotase DUF2383 PF09537.10 AFI84454.1 - 1.4e-15 57.6 0.1 6.4e-15 55.5 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF2383) DUF892 PF05974.12 AFI84454.1 - 3.7e-07 30.3 1.9 2.8e-05 24.2 2.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF892) Ferritin_2 PF13668.6 AFI84454.1 - 7.5e-06 26.2 0.3 0.0084 16.3 0.0 2.2 2 0 0 2 2 2 2 Ferritin-like domain Ferritin PF00210.24 AFI84454.1 - 0.00077 19.4 3.7 0.36 10.7 0.3 2.2 2 0 0 2 2 2 2 Ferritin-like domain COQ7 PF03232.13 AFI84454.1 - 0.0057 16.4 0.5 1.3 8.8 0.1 2.1 2 0 0 2 2 2 2 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 AFI84454.1 - 0.017 15.5 1.2 0.056 13.8 1.1 1.8 1 1 0 1 1 1 0 Rubrerythrin FMN_red PF03358.15 AFI84455.1 - 2.3e-15 56.7 0.0 3.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AFI84455.1 - 0.073 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Ion_trans_2 PF07885.16 AFI84456.1 - 4.8e-08 32.9 6.1 4.8e-08 32.9 6.1 2.1 2 0 0 2 2 2 1 Ion channel Spuma_A9PTase PF03539.14 AFI84457.1 - 0.026 14.7 0.3 0.027 14.6 0.3 1.1 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Sigma70_r4_2 PF08281.12 AFI84458.1 - 6.1e-16 57.8 0.0 1.3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI84458.1 - 1.5e-13 50.3 0.1 2.4e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI84458.1 - 7.2e-08 31.8 0.0 1.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AFI84458.1 - 0.00012 21.9 0.0 0.0023 17.9 0.0 2.8 3 0 0 3 3 3 1 HTH domain HTH_23 PF13384.6 AFI84458.1 - 0.00062 19.5 0.5 0.0015 18.2 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AFI84458.1 - 0.0012 18.8 0.1 0.0027 17.6 0.1 1.5 1 1 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 AFI84458.1 - 0.0041 16.6 0.1 0.0097 15.4 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 AFI84458.1 - 0.0058 16.2 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_40 PF14493.6 AFI84458.1 - 0.025 15.0 0.0 0.13 12.7 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.6 AFI84458.1 - 0.027 14.8 0.2 0.078 13.3 0.2 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AFI84458.1 - 0.032 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 AFI84458.1 - 0.034 14.2 0.3 0.2 11.7 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix HTH_38 PF13936.6 AFI84458.1 - 0.036 13.8 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 AFI84458.1 - 0.073 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase KORA PF16509.5 AFI84458.1 - 0.082 13.2 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Fe_dep_repress PF01325.19 AFI84458.1 - 0.094 12.9 0.2 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain DUF3885 PF13021.6 AFI84458.1 - 0.095 12.8 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) SseB_C PF14581.6 AFI84458.1 - 0.18 12.0 0.0 0.43 10.7 0.0 1.7 2 0 0 2 2 2 0 SseB protein C-terminal domain FecR PF04773.13 AFI84459.1 - 1.6e-16 60.7 0.2 2.7e-16 60.0 0.2 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI84459.1 - 7.8e-14 51.3 2.6 1.3e-13 50.6 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AFI84459.1 - 0.078 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) TonB_dep_Rec PF00593.24 AFI84461.1 - 2.5e-37 129.9 35.6 2.5e-37 129.9 35.6 2.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI84461.1 - 2e-16 60.5 0.3 2e-16 60.5 0.3 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI84461.1 - 1.2e-06 28.3 0.1 2.4e-05 24.0 0.0 2.7 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain PATR PF12951.7 AFI84463.1 - 0.33 11.1 2.0 0.64 10.2 2.0 1.5 1 0 0 1 1 1 0 Passenger-associated-transport-repeat HemolysinCabind PF00353.19 AFI84464.1 - 1.4e-35 120.8 128.0 5.1e-08 32.8 20.9 9.3 7 1 4 11 11 11 9 RTX calcium-binding nonapeptide repeat (4 copies) T2SSG PF08334.11 AFI84465.1 - 1.3e-41 141.0 1.5 1.6e-41 140.7 1.5 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AFI84465.1 - 4.5e-09 35.5 1.2 6.3e-09 35.0 1.2 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSF PF00482.23 AFI84466.1 - 1.9e-51 173.3 12.3 1.7e-26 92.6 3.7 2.3 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F Acetyltransf_11 PF13720.6 AFI84466.1 - 0.045 14.2 0.2 0.63 10.5 0.1 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF996 PF06195.13 AFI84466.1 - 0.27 11.5 6.8 0.13 12.5 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF996) T2SSE PF00437.20 AFI84467.1 - 1.3e-75 254.0 0.1 2e-75 253.4 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AFI84467.1 - 1.9e-12 47.4 1.7 7.7e-12 45.4 1.4 2.3 2 1 0 2 2 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_16 PF13191.6 AFI84467.1 - 0.0027 18.1 0.1 0.12 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AFI84467.1 - 0.0098 16.2 0.2 0.033 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AFI84467.1 - 0.011 16.1 0.2 0.039 14.3 0.2 1.9 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AFI84467.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 AFI84467.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AFI84467.1 - 0.018 14.8 0.2 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 AFI84467.1 - 0.021 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AFI84467.1 - 0.026 14.2 0.5 0.077 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AFI84467.1 - 0.039 13.9 0.1 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 AFI84467.1 - 0.042 13.4 0.6 0.3 10.6 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 AFI84467.1 - 0.06 13.9 0.2 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 AFI84467.1 - 0.067 13.6 0.3 0.66 10.4 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AFI84467.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 AFI84467.1 - 0.074 13.5 0.1 0.074 13.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 AFI84467.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ResIII PF04851.15 AFI84467.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit YrhC PF14143.6 AFI84469.1 - 0.064 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 YrhC-like protein Ly49 PF08391.10 AFI84469.1 - 0.092 13.1 0.1 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region FAM101 PF15068.6 AFI84469.1 - 0.094 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 FAM101 family PilO PF04350.13 AFI84470.1 - 1.7e-05 25.0 0.6 2.3e-05 24.6 0.6 1.3 1 0 0 1 1 1 1 Pilus assembly protein, PilO MMM1 PF10296.9 AFI84470.1 - 0.033 13.2 0.3 0.039 13.0 0.3 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 HofP PF10748.9 AFI84471.1 - 0.05 13.2 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 DNA utilization proteins HofP LysM PF01476.20 AFI84471.1 - 0.13 12.3 0.2 0.39 10.8 0.1 1.9 2 0 0 2 2 2 0 LysM domain Secretin PF00263.21 AFI84472.1 - 1.2e-39 135.7 3.2 3e-39 134.4 3.2 1.7 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein TPR_14 PF13428.6 AFI84472.1 - 3.8e-06 27.3 4.5 0.57 11.2 1.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat STN PF07660.14 AFI84472.1 - 4.3e-06 26.4 4.6 0.00077 19.2 0.4 3.7 3 1 1 4 4 4 2 Secretin and TonB N terminus short domain DUF4974 PF16344.5 AFI84472.1 - 0.00054 19.9 0.3 0.0012 18.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) TPR_19 PF14559.6 AFI84472.1 - 0.0013 19.2 6.8 1.9 9.1 0.6 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Secretin_N PF03958.17 AFI84472.1 - 0.0059 17.0 1.9 0.028 14.8 0.5 2.7 2 1 0 2 2 2 1 Bacterial type II/III secretion system short domain Fis1_TPR_C PF14853.6 AFI84472.1 - 0.31 11.1 2.3 1 9.5 0.3 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 AFI84472.1 - 0.34 11.4 5.3 0.27 11.7 1.2 2.6 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 AFI84472.1 - 0.54 11.0 6.7 22 6.0 1.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 AFI84472.1 - 0.67 10.7 7.8 8.1 7.4 2.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat N_methyl PF07963.12 AFI84473.1 - 5e-09 35.3 0.3 7.1e-09 34.9 0.3 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 AFI84474.1 - 5.2e-07 29.0 4.6 7.8e-07 28.4 4.6 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSG PF08334.11 AFI84474.1 - 0.0091 16.1 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein G ABC_tran PF00005.27 AFI84476.1 - 4.5e-30 104.9 0.0 8.6e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AFI84476.1 - 6.8e-13 48.9 14.8 9.9e-13 48.4 14.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AFI84476.1 - 7.2e-08 32.1 0.1 1.9e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AFI84476.1 - 1.2e-05 25.3 0.0 0.17 11.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AFI84476.1 - 0.0064 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 AFI84476.1 - 0.0075 16.0 0.2 0.019 14.7 0.2 1.8 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 AFI84476.1 - 0.02 14.6 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AFI84476.1 - 0.025 14.9 0.1 0.43 10.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AFI84476.1 - 0.03 14.5 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AFI84476.1 - 0.065 13.8 0.0 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1056 PF06341.11 AFI84476.1 - 0.069 13.5 0.6 0.069 13.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) PhoH PF02562.16 AFI84476.1 - 0.072 12.5 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 AFI84476.1 - 0.077 12.9 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 AFI84476.1 - 0.095 13.1 0.1 1 9.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AFI84476.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF325 PF03804.13 AFI84476.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral proteins of unknown function AAA_24 PF13479.6 AFI84476.1 - 0.14 11.9 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain FAM25 PF15825.5 AFI84476.1 - 0.2 12.0 0.8 0.35 11.2 0.0 1.8 2 0 0 2 2 1 0 FAM25 family HlyD PF00529.20 AFI84477.1 - 1.1e-18 66.9 0.1 1.7e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 AFI84477.1 - 3.9e-15 56.4 2.3 4.7e-13 49.8 0.0 3.0 3 0 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI84477.1 - 3.4e-08 33.2 1.2 0.00018 21.3 0.2 3.6 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AFI84477.1 - 3.6e-06 26.4 8.0 0.0011 18.2 0.4 2.9 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AFI84477.1 - 0.00039 20.2 1.0 0.0036 17.1 0.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 AFI84477.1 - 0.024 14.6 0.4 10 6.2 0.1 2.9 3 1 0 3 3 2 0 RnfC Barrel sandwich hybrid domain Tup_N PF08581.10 AFI84477.1 - 0.064 13.6 2.6 0.2 12.0 2.6 1.9 1 1 0 1 1 1 0 Tup N-terminal Spc7 PF08317.11 AFI84477.1 - 0.07 12.0 10.0 0.23 10.3 10.0 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 AFI84477.1 - 0.072 13.4 6.5 4.7 7.6 3.6 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 AFI84477.1 - 0.12 12.4 9.0 1.4 8.9 3.6 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 AFI84477.1 - 0.18 12.3 2.2 4 8.0 0.1 2.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 AFI84477.1 - 0.19 10.8 6.3 0.31 10.1 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 AFI84477.1 - 0.43 11.3 7.3 0.87 10.3 5.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF948 PF06103.11 AFI84477.1 - 0.66 10.3 3.9 21 5.5 0.1 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4559 PF15112.6 AFI84477.1 - 0.78 9.4 5.4 0.26 10.9 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) FAM76 PF16046.5 AFI84477.1 - 0.85 8.9 2.4 1.3 8.3 2.4 1.3 1 0 0 1 1 1 0 FAM76 protein Baculo_PEP_C PF04513.12 AFI84477.1 - 0.88 9.6 6.6 1.7 8.7 2.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 AFI84477.1 - 1.3 9.6 13.6 72 3.9 13.6 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 AFI84477.1 - 1.6 8.0 10.2 4 6.7 7.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 AFI84477.1 - 1.8 8.8 7.2 0.47 10.6 3.2 2.2 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 AFI84477.1 - 2.3 8.4 12.3 4.4 7.5 12.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 AFI84477.1 - 7 6.9 14.2 6.6 7.0 0.8 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Med21 PF11221.8 AFI84477.1 - 8.2 6.7 10.4 0.29 11.4 1.5 2.3 1 1 0 2 2 2 0 Subunit 21 of Mediator complex OEP PF02321.18 AFI84478.1 - 5.1e-55 186.2 31.4 9.6e-34 116.8 10.4 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein MotA_ExbB PF01618.16 AFI84479.1 - 1.5e-36 124.9 1.1 2.1e-36 124.4 1.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AFI84480.1 - 5.8e-29 100.9 3.2 6.5e-29 100.7 3.2 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_C PF03544.14 AFI84481.1 - 8.2e-12 45.4 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AFI84481.1 - 0.0015 18.7 0.0 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 TonB C terminal DUF488 PF04343.13 AFI84482.1 - 4.8e-12 46.5 0.2 6e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF488 CsrA PF02599.16 AFI84483.1 - 3e-27 94.3 1.5 3.4e-27 94.1 1.5 1.0 1 0 0 1 1 1 1 Global regulator protein family AA_kinase PF00696.28 AFI84484.1 - 2.9e-53 180.9 1.0 5.4e-53 180.1 1.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AFI84484.1 - 2e-20 72.4 0.3 2.9e-15 55.8 0.4 2.8 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AFI84484.1 - 1.4e-19 69.6 0.2 1e-10 41.2 0.0 2.9 2 0 0 2 2 2 2 ACT domain tRNA-synt_2c PF01411.19 AFI84485.1 - 7.6e-231 767.4 0.0 1e-230 767.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AFI84485.1 - 4.9e-29 101.5 2.9 1.2e-28 100.2 2.9 1.7 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 AFI84485.1 - 9.7e-18 64.0 1.9 2.2e-17 62.9 1.2 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3450 PF11932.8 AFI84485.1 - 0.017 14.5 2.6 0.035 13.4 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CALCOCO1 PF07888.11 AFI84485.1 - 0.021 13.7 2.3 0.033 13.1 2.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 AFI84485.1 - 0.021 14.9 3.0 0.053 13.6 3.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Zw10 PF06248.13 AFI84485.1 - 0.06 11.9 0.6 0.099 11.2 0.6 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 SPATA1_C PF15743.5 AFI84485.1 - 0.077 13.1 1.3 0.14 12.2 1.3 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Prefoldin_2 PF01920.20 AFI84485.1 - 0.13 12.2 3.6 0.38 10.7 3.6 1.8 1 0 0 1 1 1 0 Prefoldin subunit Spc7 PF08317.11 AFI84485.1 - 0.15 11.0 4.0 0.32 9.8 4.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 AFI84485.1 - 0.16 11.5 2.2 0.5 9.9 2.2 1.8 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Uso1_p115_C PF04871.13 AFI84485.1 - 0.18 12.1 4.0 0.41 11.0 3.2 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KxDL PF10241.9 AFI84485.1 - 0.46 10.8 3.5 0.34 11.2 0.5 2.4 3 0 0 3 3 1 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.9 AFI84485.1 - 1.6 8.8 8.1 3.6 7.6 6.2 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 AFI84485.1 - 2.4 8.6 8.6 9.9 6.7 0.0 3.3 3 1 0 3 3 2 0 Snapin/Pallidin Seryl_tRNA_N PF02403.22 AFI84485.1 - 3 8.1 9.3 8.4 6.7 4.8 3.2 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain RecX PF02631.16 AFI84486.1 - 1.6e-33 115.8 3.8 1.6e-33 115.8 3.8 1.7 1 1 1 2 2 2 1 RecX family DUF494 PF04361.13 AFI84486.1 - 0.00011 22.2 2.3 0.0017 18.2 0.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF494) Raf1_HTH PF18579.1 AFI84486.1 - 0.0011 18.6 1.8 12 5.7 0.1 3.8 3 1 1 4 4 4 3 Rubisco accumulation factor 1 helix turn helix domain UBA_3 PF09288.10 AFI84486.1 - 0.034 14.0 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain PanZ PF12568.8 AFI84486.1 - 0.05 13.3 0.6 0.12 12.1 0.6 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DUF2381 PF09544.10 AFI84486.1 - 0.06 12.9 1.9 0.083 12.4 1.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2381) RecA PF00154.21 AFI84487.1 - 7.3e-147 487.8 2.4 8.9e-147 487.6 2.4 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AFI84487.1 - 4.5e-10 39.2 0.4 1.3e-09 37.7 0.4 1.6 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AFI84487.1 - 5.5e-08 32.4 1.5 2.8e-06 26.9 1.5 2.7 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 AFI84487.1 - 8.1e-06 25.9 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AFI84487.1 - 0.00038 20.2 0.0 0.00064 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AFI84487.1 - 0.0015 18.1 0.7 0.015 14.9 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AFI84487.1 - 0.023 15.1 0.1 0.062 13.7 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI84487.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 AFI84487.1 - 0.085 12.8 0.1 0.46 10.4 0.0 2.1 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.16 AFI84487.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CinA PF02464.17 AFI84488.1 - 5.2e-58 195.0 0.0 5.8e-58 194.8 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein MutS_V PF00488.21 AFI84489.1 - 2e-84 282.3 0.1 5.2e-84 281.0 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AFI84489.1 - 6.5e-42 142.3 0.0 1.6e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 AFI84489.1 - 5.9e-39 134.3 5.3 1.1e-38 133.4 5.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 AFI84489.1 - 9.4e-29 99.6 0.7 2.1e-28 98.5 0.7 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 AFI84489.1 - 2.3e-25 89.4 0.0 8.8e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain II YcgL PF05166.13 AFI84490.1 - 4e-30 104.0 0.1 4.7e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 YcgL domain AHJR-like PF18743.1 AFI84490.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 REase_AHJR-like Glyoxalase PF00903.25 AFI84491.1 - 7.1e-15 55.3 0.0 8e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AFI84491.1 - 0.0042 17.9 0.0 0.0088 16.8 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AFI84491.1 - 0.0082 16.1 0.0 0.068 13.1 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 AFI84491.1 - 0.014 15.7 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily OsmC PF02566.19 AFI84492.1 - 2.2e-18 66.6 0.0 2.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein cNMP_binding PF00027.29 AFI84493.1 - 1.2e-15 57.3 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Crp PF00325.20 AFI84493.1 - 3.9e-09 36.0 0.2 7.8e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_Crp_2 PF13545.6 AFI84493.1 - 5.4e-08 32.7 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF977 PF06163.11 AFI84493.1 - 0.00032 20.7 0.2 0.0023 17.9 0.2 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF977) HTH_23 PF13384.6 AFI84493.1 - 0.0042 16.8 0.2 0.0085 15.9 0.2 1.5 1 0 0 1 1 1 1 Homeodomain-like domain SgrR_N PF12793.7 AFI84493.1 - 0.0088 16.3 0.3 0.023 14.9 0.1 1.7 2 0 0 2 2 2 1 Sugar transport-related sRNA regulator N-term Phage_rep_O PF04492.13 AFI84493.1 - 0.027 15.0 0.1 0.075 13.6 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage replication protein O TrmB PF01978.19 AFI84493.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 AFI84493.1 - 0.084 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain IGPS PF00218.21 AFI84494.1 - 2.3e-98 328.4 0.3 2.6e-98 328.3 0.3 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 AFI84494.1 - 0.00052 19.8 0.1 0.00091 19.0 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 AFI84494.1 - 0.12 11.5 0.2 9.7 5.3 0.0 3.0 3 1 1 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase Glycos_transf_3 PF00591.21 AFI84495.1 - 1.2e-101 339.6 4.5 1.2e-101 339.6 4.5 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AFI84495.1 - 3.9e-17 61.9 7.1 1.2e-16 60.3 6.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DUF434 PF04256.12 AFI84495.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF434) GATase PF00117.28 AFI84496.1 - 9.8e-58 195.1 0.2 1.1e-57 194.9 0.2 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AFI84496.1 - 2.8e-11 43.6 0.7 7.8e-11 42.1 0.7 1.6 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AFI84496.1 - 0.014 15.2 0.0 0.048 13.5 0.0 1.7 1 1 0 1 1 1 0 SNO glutamine amidotransferase family GATase_5 PF13507.6 AFI84496.1 - 0.14 11.2 0.2 9.9 5.2 0.0 2.1 1 1 1 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Chorismate_bind PF00425.18 AFI84497.1 - 1e-99 333.3 0.0 2.6e-99 332.0 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AFI84497.1 - 4e-35 121.1 0.0 3.1e-33 115.0 0.0 3.2 4 0 0 4 4 4 1 Anthranilate synthase component I, N terminal region Cytochrom_B562 PF07361.11 AFI84497.1 - 0.13 13.0 0.1 0.35 11.5 0.1 1.7 1 0 0 1 1 1 0 Cytochrome b562 HAD_2 PF13419.6 AFI84498.1 - 1.1e-35 123.3 0.0 1.3e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI84498.1 - 3.4e-21 76.5 0.0 2.7e-20 73.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI84498.1 - 3.3e-11 44.0 0.0 4.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI84498.1 - 5.6e-10 39.1 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 AFI84498.1 - 0.00085 19.1 0.6 5.6 6.6 0.0 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AFI84498.1 - 0.021 15.0 0.1 0.096 12.8 0.1 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribul_P_3_epim PF00834.19 AFI84499.1 - 1.6e-88 295.3 0.1 1.8e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AFI84499.1 - 3.2e-05 23.8 0.0 0.0079 16.0 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain PGM_PMM_II PF02879.16 AFI84499.1 - 0.03 14.9 0.0 0.75 10.4 0.0 2.5 2 1 1 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF3530 PF12048.8 AFI84500.1 - 1.4e-35 123.3 9.7 2.5e-35 122.4 9.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3530) DLH PF01738.18 AFI84500.1 - 7.9e-05 22.3 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 AFI84500.1 - 0.0032 17.1 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 AFI84500.1 - 0.05 13.5 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AFI84500.1 - 0.11 11.7 0.1 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1057 PF06342.12 AFI84500.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Spermine_synth PF01564.17 AFI84501.1 - 5.6e-12 45.5 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 AFI84501.1 - 0.00099 19.8 0.1 0.0019 18.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84501.1 - 0.12 13.1 0.1 0.33 11.7 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain YkuD PF03734.14 AFI84502.1 - 1.5e-19 70.8 0.0 2e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Radical_SAM_N PF08497.10 AFI84503.1 - 5.4e-143 475.6 0.0 8.1e-143 475.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM N-terminal DUF3362 PF11842.8 AFI84503.1 - 1.2e-48 165.2 0.6 2.1e-48 164.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) Radical_SAM PF04055.21 AFI84503.1 - 4.8e-20 72.6 0.0 2.1e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AFI84503.1 - 0.03 14.3 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain Ni_hydr_CYTB PF01292.20 AFI84504.1 - 6.3e-24 84.6 17.3 8.6e-24 84.1 17.3 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 AFI84504.1 - 0.00015 21.9 9.6 0.011 15.9 3.7 2.6 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 DUF4405 PF14358.6 AFI84504.1 - 0.00077 20.0 2.7 0.00077 20.0 2.7 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4405) DUF4079 PF13301.6 AFI84504.1 - 0.024 14.8 9.3 0.45 10.7 2.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF5134 PF17197.4 AFI84504.1 - 1 9.2 6.1 0.52 10.2 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) YceI PF04264.13 AFI84505.1 - 4.1e-33 115.0 0.1 4.9e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 YceI-like domain HMG_CoA_synt_C PF08540.10 AFI84505.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Peptidase_M22 PF00814.25 AFI84508.1 - 9.8e-29 100.9 0.3 4.4e-28 98.7 0.3 1.7 1 1 0 1 1 1 1 Glycoprotease family Methyltransf_25 PF13649.6 AFI84509.1 - 2.5e-11 44.1 0.0 5.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI84509.1 - 7.1e-11 42.6 0.0 1.4e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84509.1 - 1e-10 42.2 0.0 2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI84509.1 - 1.6e-10 41.0 0.1 2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI84509.1 - 3.6e-07 30.2 0.0 5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 AFI84509.1 - 9.4e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 AFI84509.1 - 0.00038 20.1 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AFI84509.1 - 0.00066 19.2 0.1 0.00099 18.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 AFI84509.1 - 0.00097 18.7 0.3 0.15 11.6 0.1 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 AFI84509.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 AFI84509.1 - 0.0031 17.5 0.2 0.0051 16.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 AFI84509.1 - 0.011 15.3 0.0 0.28 10.7 0.0 2.1 1 1 0 1 1 1 0 Histone methylation protein DOT1 Bin3 PF06859.12 AFI84509.1 - 0.018 15.6 0.0 0.077 13.6 0.0 2.0 1 1 1 2 2 2 0 Bicoid-interacting protein 3 (Bin3) PCMT PF01135.19 AFI84509.1 - 0.02 14.6 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 AFI84509.1 - 0.049 13.5 0.1 0.082 12.7 0.1 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.6 AFI84509.1 - 0.14 13.2 0.0 0.29 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 AFI84510.1 - 3.2e-134 446.8 0.2 3.6e-134 446.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 AFI84510.1 - 2.5e-09 37.2 0.0 4.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI84510.1 - 8.5e-08 32.1 0.0 2.1e-06 27.6 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI84510.1 - 1.5e-06 28.8 0.0 4.3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI84510.1 - 2.5e-06 28.1 0.0 9.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84510.1 - 0.00024 21.8 0.0 0.00046 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AFI84510.1 - 0.00098 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 AFI84510.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AFI84510.1 - 0.23 11.0 0.1 1 8.9 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase small domain Cys_rich_CPXG PF14255.6 AFI84513.1 - 4.6e-20 71.2 5.1 5.3e-20 71.1 5.1 1.1 1 0 0 1 1 1 1 Cysteine-rich CPXCG DUF3268 PF11672.8 AFI84513.1 - 0.0052 17.1 1.3 0.0057 17.0 1.3 1.1 1 0 0 1 1 1 1 zinc-finger-containing domain zf-ribbon_3 PF13248.6 AFI84513.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Acetyltransf_7 PF13508.7 AFI84515.1 - 2.6e-11 43.8 0.0 3.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AFI84515.1 - 9.4e-09 35.5 0.0 1.2e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AFI84515.1 - 1.7e-08 34.4 0.0 3.2e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AFI84515.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AFI84515.1 - 0.0084 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_16 PF05301.11 AFI84515.1 - 0.062 13.1 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase, Mec-17 GNAT_acetyltr_2 PF13718.6 AFI84515.1 - 0.16 11.4 0.0 0.37 10.2 0.0 1.5 1 1 1 2 2 2 0 GNAT acetyltransferase 2 CitMHS PF03600.16 AFI84516.1 - 3.9e-39 134.6 43.7 2e-24 86.3 18.8 2.2 1 1 1 2 2 2 2 Citrate transporter TrkA_C PF02080.21 AFI84516.1 - 1.1e-21 76.5 0.3 4.9e-10 39.1 0.1 2.4 2 0 0 2 2 2 2 TrkA-C domain DctM PF06808.12 AFI84516.1 - 0.0027 16.6 18.1 0.0027 16.6 18.1 2.7 2 1 0 2 2 2 1 Tripartite ATP-independent periplasmic transporter, DctM component Lipocalin_2 PF08212.12 AFI84517.1 - 2.5e-41 141.0 0.1 2.9e-41 140.8 0.1 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 AFI84517.1 - 0.00075 19.7 0.1 0.0015 18.7 0.1 1.5 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family GH43_C PF16369.5 AFI84517.1 - 0.073 13.7 0.3 0.2 12.3 0.3 1.8 1 1 0 1 1 1 0 C-terminal lipocalin-like domain MLTD_N PF06474.12 AFI84517.1 - 0.15 12.3 0.4 0.25 11.5 0.4 1.4 1 0 0 1 1 1 0 MltD lipid attachment motif Ion_trans PF00520.31 AFI84518.1 - 1.2e-43 149.1 23.4 1.4e-43 148.9 23.4 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 AFI84518.1 - 1.5e-07 30.5 21.9 5.3e-07 28.7 21.9 1.8 1 1 0 1 1 1 1 Polycystin cation channel DUF962 PF06127.11 AFI84518.1 - 0.0059 16.7 0.0 0.038 14.1 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF962) DUF2973 PF11189.8 AFI84518.1 - 0.032 14.3 0.1 0.032 14.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) Arc PF03869.14 AFI84519.1 - 9.4e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Arc-like DNA binding domain SAWADEE PF16719.5 AFI84519.1 - 0.13 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 SAWADEE domain EAL PF00563.20 AFI84520.1 - 2.1e-63 214.1 0.2 4.1e-63 213.1 0.2 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI84520.1 - 2.1e-34 118.6 0.0 1e-33 116.4 0.1 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AFI84520.1 - 1.4e-13 51.0 0.0 3.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AFI84520.1 - 3.2e-11 43.2 0.1 6.6e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI84520.1 - 4.1e-07 29.9 0.0 2.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 AFI84520.1 - 1.6e-06 28.3 0.0 4.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI84520.1 - 1.2e-05 25.5 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold GCH_III PF05165.12 AFI84520.1 - 0.027 13.7 0.1 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase III MerC PF03203.14 AFI84521.1 - 7e-27 94.2 6.0 7.9e-27 94.0 6.0 1.0 1 0 0 1 1 1 1 MerC mercury resistance protein PrgI PF12666.7 AFI84521.1 - 0.45 11.2 1.9 0.95 10.2 0.3 2.0 1 1 1 2 2 2 0 PrgI family protein zf-dskA_traR PF01258.17 AFI84522.1 - 5.5e-09 35.8 0.2 1.4e-08 34.5 0.2 1.8 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger CSS-motif PF12792.7 AFI84522.1 - 0.05 13.1 0.0 0.09 12.2 0.0 1.4 1 1 0 1 1 1 0 CSS motif domain associated with EAL cobW PF02492.19 AFI84523.1 - 1.2e-56 191.0 3.3 1.6e-56 190.7 3.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AFI84523.1 - 7.6e-28 96.3 0.0 1.8e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 AFI84523.1 - 0.00015 21.7 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 AFI84523.1 - 0.00096 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 AFI84523.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AFI84523.1 - 0.018 15.4 0.1 0.037 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 AFI84523.1 - 0.025 15.1 0.1 0.075 13.5 0.1 1.9 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 AFI84523.1 - 0.027 14.6 0.1 0.058 13.5 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 AFI84523.1 - 0.039 13.2 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 AFI84523.1 - 0.046 12.6 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 AFI84523.1 - 0.048 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 AFI84523.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 AFI84523.1 - 0.083 12.3 0.6 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 AFI84523.1 - 0.084 11.8 0.0 0.63 9.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 AFI84523.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1826 PF08856.11 AFI84524.1 - 1.5e-05 25.0 0.0 1.5e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) DUF1826 PF08856.11 AFI84525.1 - 7.2e-25 88.1 0.1 8e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) DUF2796 PF10986.8 AFI84526.1 - 2e-36 125.5 3.4 1.1e-22 80.8 0.8 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF2796) L6_membrane PF05805.12 AFI84526.1 - 0.2 11.2 0.2 0.39 10.3 0.0 1.5 2 0 0 2 2 2 0 L6 membrane protein FUR PF01475.19 AFI84527.1 - 6.9e-14 52.0 1.5 9e-14 51.6 1.5 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 AFI84527.1 - 0.0016 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain PadR PF03551.14 AFI84527.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family FYVE_2 PF02318.16 AFI84527.1 - 0.41 10.9 5.5 0.081 13.1 1.5 2.1 1 1 0 2 2 2 0 FYVE-type zinc finger ABC_tran PF00005.27 AFI84528.1 - 1.5e-29 103.2 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI84528.1 - 1.5e-12 48.0 0.2 9.8e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI84528.1 - 3.5e-05 23.3 0.4 8.7e-05 22.1 0.4 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AFI84528.1 - 6.4e-05 22.8 0.1 0.058 13.1 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AFI84528.1 - 0.0017 18.3 0.8 0.0088 16.0 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AFI84528.1 - 0.0088 16.6 0.3 0.018 15.5 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI84528.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 AFI84528.1 - 0.03 13.9 1.1 0.054 13.1 0.2 1.8 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain UMPH-1 PF05822.12 AFI84528.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) AAA_33 PF13671.6 AFI84528.1 - 0.037 14.2 0.3 0.15 12.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AFI84528.1 - 0.045 13.3 0.4 0.29 10.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AFI84528.1 - 0.049 12.4 0.1 0.089 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_30 PF13604.6 AFI84528.1 - 0.049 13.3 2.3 0.41 10.3 2.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AFI84528.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 AFI84528.1 - 0.077 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AFI84528.1 - 0.11 12.8 0.6 0.35 11.1 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AFI84528.1 - 0.12 12.7 1.5 0.51 10.7 1.5 2.1 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AFI84528.1 - 0.14 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 AFI84528.1 - 0.16 10.6 0.4 2.6 6.6 0.2 2.0 1 1 1 2 2 2 0 AAA domain TonB_dep_Rec PF00593.24 AFI84530.1 - 4.1e-22 79.7 28.2 4.1e-22 79.7 28.2 2.0 1 1 1 2 2 2 1 TonB dependent receptor DDE_Tnp_1_3 PF13612.6 AFI84531.1 - 1.9e-77 258.6 0.0 2.7e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI84531.1 - 7.9e-23 81.2 0.1 1.1e-21 77.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI84531.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain DUF3526 PF12040.8 AFI84533.1 - 1e-44 152.7 6.1 2e-44 151.8 6.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3526) ABC2_membrane_2 PF12679.7 AFI84533.1 - 8.3e-23 81.1 10.3 1.3e-22 80.5 10.3 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AFI84533.1 - 9e-10 38.2 17.0 9e-10 38.2 17.0 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AFI84533.1 - 5e-07 29.9 14.0 7.6e-07 29.2 11.4 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein Transport_MerF PF11431.8 AFI84533.1 - 0.085 12.8 0.1 0.085 12.8 0.1 3.0 4 0 0 4 4 4 0 Membrane transport protein MerF MSP1a PF11670.8 AFI84533.1 - 1.2 8.4 3.0 35 3.6 0.0 2.3 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) DUF3619 PF12279.8 AFI84533.1 - 6.8 7.0 7.9 0.69 10.2 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) MTABC_N PF16185.5 AFI84533.1 - 8.8 5.7 17.9 0.9 9.0 12.8 1.9 2 1 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF3526 PF12040.8 AFI84534.1 - 6.2e-32 111.2 12.2 1.1e-31 110.5 12.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3526) ABC2_membrane_2 PF12679.7 AFI84534.1 - 3.3e-08 33.2 3.7 5.8e-08 32.4 3.6 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein cobW PF02492.19 AFI84535.1 - 2.8e-40 137.8 0.0 4.4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AFI84535.1 - 0.00062 18.8 0.6 0.01 14.9 0.6 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 AFI84535.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 AFI84535.1 - 0.048 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AFI84535.1 - 0.17 11.8 0.1 8.6 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Amidohydro_3 PF07969.11 AFI84536.1 - 3.3e-48 165.3 0.4 4.5e-48 164.9 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AFI84536.1 - 0.00029 20.3 0.1 0.041 13.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family DUF3299 PF11736.8 AFI84537.1 - 3.6e-49 166.3 0.0 4.3e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3299) ABC_tran PF00005.27 AFI84538.1 - 2.5e-33 115.5 0.1 3.3e-33 115.1 0.1 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI84538.1 - 2.1e-10 40.9 2.0 1.3e-05 25.2 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AFI84538.1 - 4.4e-08 33.7 0.5 9e-08 32.7 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AFI84538.1 - 4.9e-06 26.2 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AFI84538.1 - 5.2e-06 26.1 1.0 1e-05 25.1 1.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 AFI84538.1 - 3.8e-05 24.0 0.0 8.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 AFI84538.1 - 8.9e-05 22.5 0.1 0.00033 20.6 0.0 1.9 2 1 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 AFI84538.1 - 0.00043 20.1 0.3 0.0045 16.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AFI84538.1 - 0.00048 19.8 0.1 0.059 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AFI84538.1 - 0.00096 19.1 0.2 0.0015 18.5 0.2 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 AFI84538.1 - 0.0011 18.8 0.5 0.071 12.8 0.0 2.4 1 1 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AFI84538.1 - 0.0012 19.1 1.9 0.014 15.7 1.9 2.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AFI84538.1 - 0.0021 17.5 0.1 0.89 8.9 0.0 2.3 2 1 0 2 2 2 1 KaiC Rad17 PF03215.15 AFI84538.1 - 0.003 17.5 0.1 0.034 14.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 AFI84538.1 - 0.0034 17.3 0.5 0.054 13.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 AFI84538.1 - 0.0038 17.7 2.0 0.02 15.4 2.0 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI84538.1 - 0.004 16.3 0.0 0.0086 15.2 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein PIF1 PF05970.14 AFI84538.1 - 0.0048 16.1 0.1 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_19 PF13245.6 AFI84538.1 - 0.0079 16.5 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 AFI84538.1 - 0.0091 16.1 0.3 0.019 15.0 0.3 1.6 1 1 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 AFI84538.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AFI84538.1 - 0.01 16.0 0.1 0.034 14.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AFI84538.1 - 0.011 15.7 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 AFI84538.1 - 0.012 15.4 0.1 0.055 13.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 AFI84538.1 - 0.013 16.0 0.1 0.024 15.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AFI84538.1 - 0.029 14.5 0.0 0.092 12.8 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 AFI84538.1 - 0.029 14.8 0.4 0.23 11.9 0.4 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 AFI84538.1 - 0.035 13.5 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 AFI84538.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AFI84538.1 - 0.042 13.9 0.3 0.13 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 AFI84538.1 - 0.042 13.6 0.8 0.33 10.7 0.7 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase CLP1_P PF16575.5 AFI84538.1 - 0.056 13.2 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 AFI84538.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 AFI84538.1 - 0.066 12.5 0.1 0.96 8.7 0.0 2.1 1 1 0 2 2 2 0 Septin Zeta_toxin PF06414.12 AFI84538.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 AFI84538.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 AFI84538.1 - 0.089 11.6 4.2 0.95 8.2 0.3 2.6 2 1 1 3 3 3 0 Predicted ATPase of the ABC class KAP_NTPase PF07693.14 AFI84538.1 - 0.092 12.0 0.6 0.18 11.0 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.20 AFI84538.1 - 0.1 11.8 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 AFI84538.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 AFI84538.1 - 0.16 11.5 0.6 0.64 9.5 0.1 2.3 2 1 1 3 3 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 AFI84538.1 - 0.58 8.7 3.2 1.5 7.4 0.1 2.3 1 1 0 2 2 2 0 AAA domain MacB_PCD PF12704.7 AFI84539.1 - 3.5e-12 47.1 0.3 6.2e-12 46.3 0.3 1.4 1 0 0 1 1 1 1 MacB-like periplasmic core domain FtsX PF02687.21 AFI84539.1 - 2.3e-09 37.6 4.9 2.3e-09 37.6 4.9 3.3 3 0 0 3 3 3 1 FtsX-like permease family DUF5408 PF17402.2 AFI84539.1 - 2.6 8.0 5.4 4.6 7.2 0.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF1129 PF06570.11 AFI84541.1 - 0.77 9.2 3.8 0.52 9.8 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) GGDEF PF00990.21 AFI84542.1 - 3.3e-46 157.0 0.0 4.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MASE1 PF05231.14 AFI84542.1 - 1.6e-09 37.4 42.2 2.5e-09 36.7 42.2 1.3 1 1 0 1 1 1 1 MASE1 GGDEF_2 PF17853.1 AFI84542.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 GGDEF-like domain PepSY_TM PF03929.16 AFI84544.1 - 1.2e-58 199.1 2.9 2.2e-58 198.2 2.9 1.4 1 0 0 1 1 1 1 PepSY-associated TM region PepSY_TM PF03929.16 AFI84545.1 - 7.5 6.1 9.8 0.67 9.6 0.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM region DUF2649 PF10854.8 AFI84546.1 - 0.14 12.4 4.7 0.15 12.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) TonB_dep_Rec PF00593.24 AFI84547.1 - 2.1e-37 130.1 37.5 2.1e-37 130.1 37.5 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI84547.1 - 1.6e-14 54.4 3.8 1.6e-14 54.4 3.8 2.4 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain 2-ph_phosp PF04029.14 AFI84547.1 - 0.12 11.5 0.7 0.2 10.8 0.7 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase HTH_18 PF12833.7 AFI84549.1 - 1.1e-20 73.7 0.9 2.1e-20 72.8 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AFI84549.1 - 4.8e-15 55.2 1.3 1.3e-06 28.4 0.1 3.5 4 0 0 4 4 4 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_ISL3 PF13542.6 AFI84549.1 - 0.016 14.6 0.1 0.072 12.5 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 TDP43_N PF18694.1 AFI84549.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain HTH_AsnC-type PF13404.6 AFI84549.1 - 0.064 13.1 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_8 PF02954.19 AFI84549.1 - 0.065 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family TetR_N PF00440.23 AFI84550.1 - 0.00048 19.9 0.0 0.00078 19.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family GxGYxYP_N PF16216.5 AFI84550.1 - 0.061 13.5 0.7 0.099 12.8 0.7 1.3 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal COQ9 PF08511.11 AFI84550.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 COQ9 DUF4574 PF15141.6 AFI84550.1 - 0.49 10.3 2.5 0.52 10.3 0.3 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 MS_channel PF00924.18 AFI84551.1 - 3.9e-47 160.5 0.2 6.7e-47 159.7 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel adh_short PF00106.25 AFI84552.1 - 2.3e-39 134.9 3.0 3e-39 134.5 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AFI84552.1 - 1.8e-31 109.5 5.0 2.3e-31 109.1 5.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AFI84552.1 - 8.9e-12 45.3 1.8 1.2e-11 44.8 1.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AFI84552.1 - 5.8e-06 25.9 2.3 3.7e-05 23.3 2.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AFI84552.1 - 0.00091 18.4 0.4 0.0013 17.9 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AFI84552.1 - 0.0013 18.7 2.8 0.0019 18.1 2.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AFI84552.1 - 0.014 14.4 0.3 0.023 13.7 0.3 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DNA_photolyase PF00875.18 AFI84552.1 - 0.027 14.5 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 DNA photolyase Shikimate_DH PF01488.20 AFI84552.1 - 0.059 13.4 0.3 0.17 11.9 0.3 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 AFI84552.1 - 0.095 11.9 3.0 9.1 5.4 2.1 2.9 1 1 0 2 2 2 0 Male sterility protein CSD PF00313.22 AFI84553.1 - 1.5e-29 101.6 0.9 1.6e-29 101.5 0.9 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AFI84553.1 - 0.012 15.3 0.7 0.015 14.9 0.7 1.5 1 1 0 1 1 1 0 Ribonuclease B OB domain Acyl_transf_3 PF01757.22 AFI84554.1 - 1.6e-24 86.6 47.8 2.9e-24 85.8 47.8 1.4 1 1 0 1 1 1 1 Acyltransferase family GGDEF PF00990.21 AFI84555.1 - 1.8e-44 151.4 0.1 3e-44 150.6 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 AFI84555.1 - 0.00021 21.6 0.0 0.00067 20.0 0.0 1.8 2 0 0 2 2 2 1 GAF domain DUF1818 PF08848.11 AFI84555.1 - 0.13 12.4 0.6 0.35 11.0 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1818) DUF3080 PF11279.8 AFI84556.1 - 2.2e-103 345.8 6.8 2.5e-103 345.7 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) FdtA PF05523.11 AFI84556.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal MCPsignal PF00015.21 AFI84557.1 - 5.9e-40 136.9 19.6 5.9e-40 136.9 19.6 3.4 2 1 2 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AFI84557.1 - 1.8e-12 47.4 0.4 2e-11 44.0 0.0 3.1 4 0 0 4 4 3 1 HAMP domain AI-2E_transport PF01594.16 AFI84557.1 - 0.00019 20.7 1.5 0.00019 20.7 1.5 2.9 3 1 0 3 3 3 1 AI-2E family transporter Phasin_2 PF09361.10 AFI84557.1 - 0.012 15.9 3.2 0.012 15.9 3.2 4.5 5 2 0 5 5 5 0 Phasin protein DUF948 PF06103.11 AFI84557.1 - 0.097 12.9 27.6 0.083 13.2 1.4 5.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HHH_2 PF12826.7 AFI84557.1 - 0.27 11.4 6.0 2.6 8.2 0.1 3.5 4 0 0 4 4 4 0 Helix-hairpin-helix motif DUF5383 PF17355.2 AFI84557.1 - 0.65 10.4 0.1 0.65 10.4 0.1 5.0 5 1 1 6 6 6 0 Family of unknown function (DUF5383) FadA PF09403.10 AFI84557.1 - 1.7 9.2 22.4 13 6.3 0.9 6.0 5 1 1 6 6 6 0 Adhesion protein FadA TMPIT PF07851.13 AFI84557.1 - 1.8 7.7 13.0 0.7 9.1 5.9 2.9 2 1 0 2 2 2 0 TMPIT-like protein Cauli_AT PF03233.13 AFI84557.1 - 3 7.7 10.3 0.21 11.5 1.2 3.0 3 0 0 3 3 3 0 Aphid transmission protein Vps53_N PF04100.12 AFI84557.1 - 4.5 6.1 15.7 0.13 11.2 5.9 3.0 2 1 1 3 3 3 0 Vps53-like, N-terminal Gp45_2 PF17470.2 AFI84558.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage gene product 45.2 DDE_Tnp_1_3 PF13612.6 AFI84559.1 - 1.9e-77 258.6 0.0 2.7e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI84559.1 - 7.9e-23 81.2 0.1 1.1e-21 77.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI84559.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain HTH_28 PF13518.6 AFI84560.1 - 7.2e-08 32.4 0.2 1.2e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI84560.1 - 1.5e-07 31.0 0.0 2.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AFI84560.1 - 1.2e-06 28.4 0.0 4.1e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AFI84560.1 - 0.002 17.8 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 FaeA PF04703.12 AFI84560.1 - 0.016 15.5 0.9 0.019 15.3 0.0 1.6 2 0 0 2 2 2 0 FaeA-like protein FMN_red PF03358.15 AFI84561.1 - 1.2e-27 96.5 0.0 1.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AFI84561.1 - 4.6e-06 26.5 0.0 5.6e-06 26.2 0.0 1.2 1 1 0 1 1 1 1 Flavodoxin-like fold Cupin_3 PF05899.12 AFI84562.1 - 3.1e-23 81.3 0.1 3.7e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AFI84562.1 - 9.5e-07 28.5 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AFI84562.1 - 0.0064 16.2 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 AFI84562.1 - 0.0092 15.8 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ TonB_dep_Rec PF00593.24 AFI84563.1 - 4.4e-40 139.0 36.4 4.4e-40 139.0 36.4 2.3 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI84563.1 - 3.4e-16 59.7 0.1 1e-15 58.2 0.1 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Malic_M PF03949.15 AFI84564.1 - 3.3e-97 324.8 0.7 5.4e-97 324.1 0.7 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AFI84564.1 - 1.5e-72 243.2 0.0 2.3e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2845 PF11006.8 AFI84565.1 - 2.4e-05 24.3 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) PPDFL PF15060.6 AFI84565.1 - 0.08 13.5 0.0 0.096 13.2 0.0 1.2 1 0 0 1 1 1 0 Differentiation and proliferation regulator HlyD_3 PF13437.6 AFI84567.1 - 2.5e-15 57.1 3.4 1.4e-11 45.0 0.1 2.7 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AFI84567.1 - 2.4e-13 49.8 7.4 1.6e-11 43.8 7.4 2.1 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AFI84567.1 - 7.8e-11 41.6 0.1 2.9e-10 39.8 0.1 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AFI84567.1 - 0.00011 21.9 0.3 0.0022 17.8 0.1 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AFI84567.1 - 0.03 14.5 0.8 0.2 11.9 0.0 2.5 2 1 1 3 3 3 0 Peptidase family M23 E2R135 PF11570.8 AFI84567.1 - 2.6 8.4 7.2 0.24 11.7 1.7 2.0 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 HlyD PF00529.20 AFI84567.1 - 4.6 7.2 10.5 6.9 6.6 10.5 1.4 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS ABC_tran PF00005.27 AFI84568.1 - 5.3e-59 198.6 0.0 1.2e-28 100.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 AFI84568.1 - 5.3e-37 127.7 10.3 8e-37 127.1 10.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AFI84568.1 - 5.8e-20 71.6 21.5 2.4e-19 69.6 18.0 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AFI84568.1 - 7.6e-19 68.1 10.1 1.3e-18 67.3 10.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 AFI84568.1 - 1.4e-18 67.8 0.9 3.3e-05 23.9 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_4 PF12730.7 AFI84568.1 - 9.5e-05 22.4 13.2 9.5e-05 22.4 13.2 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 AFI84568.1 - 0.00022 21.2 0.1 0.057 13.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 AFI84568.1 - 0.00038 20.5 0.0 0.093 12.8 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.6 AFI84568.1 - 0.00057 20.4 0.2 0.19 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AFI84568.1 - 0.0011 18.7 0.4 2.2 8.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI84568.1 - 0.0015 18.9 0.0 0.83 10.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 AFI84568.1 - 0.0054 16.5 1.1 1.3 8.6 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 AFI84568.1 - 0.012 15.9 0.4 3.7 7.8 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AFI84568.1 - 0.013 15.9 0.0 7 7.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AFI84568.1 - 0.02 14.6 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AFI84568.1 - 0.031 14.3 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 AFI84568.1 - 0.041 14.1 0.0 16 5.8 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 AFI84568.1 - 0.064 13.2 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain SMC_N PF02463.19 AFI84568.1 - 0.066 12.6 0.7 15 4.9 0.0 3.7 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 AFI84568.1 - 0.076 13.4 0.2 5 7.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Fijivirus_P9-2 PF06837.11 AFI84568.1 - 0.21 11.0 4.3 0.4 10.1 4.3 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein AAA_28 PF13521.6 AFI84568.1 - 0.32 11.2 2.5 12 6.1 0.5 3.2 3 0 0 3 3 3 0 AAA domain UPF0182 PF03699.13 AFI84568.1 - 1.2 7.2 5.3 1.8 6.6 5.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ABC2_membrane_3 PF12698.7 AFI84569.1 - 1.4e-34 119.7 12.8 2e-34 119.3 12.8 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AFI84569.1 - 9.4e-26 90.5 12.6 9.4e-26 90.5 12.6 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AFI84569.1 - 2.7e-15 56.4 11.9 6.2e-15 55.2 11.9 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AFI84569.1 - 0.00012 22.1 12.6 0.00012 22.1 12.6 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein HAD_2 PF13419.6 AFI84570.1 - 2.1e-33 115.9 0.1 2.5e-33 115.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI84570.1 - 4.8e-16 59.7 0.0 3e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI84570.1 - 4.9e-07 29.7 0.0 9.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AFI84570.1 - 0.00061 19.9 0.2 0.29 11.3 0.0 2.8 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI84570.1 - 0.0039 17.6 0.0 0.0049 17.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lipase_GDSL_2 PF13472.6 AFI84571.1 - 1.5e-23 84.1 0.0 2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AFI84571.1 - 1.6e-09 38.1 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ABC_tran PF00005.27 AFI84572.1 - 1.8e-33 116.0 0.0 2.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI84572.1 - 2.4e-06 27.6 1.2 0.029 14.2 0.7 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI84572.1 - 3.1e-06 26.8 0.1 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AFI84572.1 - 0.00069 19.9 1.1 0.015 15.6 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI84572.1 - 0.00098 18.8 0.2 0.002 17.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI84572.1 - 0.0019 18.6 0.6 0.0048 17.3 0.6 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AFI84572.1 - 0.016 14.9 0.2 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AFI84572.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 AFI84572.1 - 0.047 13.3 0.2 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 AFI84572.1 - 0.074 12.4 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 AFI84572.1 - 0.17 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsX PF02687.21 AFI84573.1 - 2.6e-11 43.9 7.7 4.5e-09 36.6 0.3 5.4 5 1 1 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 AFI84573.1 - 2e-05 25.0 7.8 0.00025 21.4 0.0 3.2 4 0 0 4 4 4 2 MacB-like periplasmic core domain Nucleoporin_C PF03177.14 AFI84573.1 - 0.019 13.7 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Transgly PF00912.22 AFI84574.1 - 1.1e-47 161.8 0.0 1.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SnoaL_2 PF12680.7 AFI84575.1 - 0.076 13.7 0.0 0.082 13.6 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain TUG-UBL1 PF11470.8 AFI84575.1 - 0.088 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain DUF2789 PF10982.8 AFI84576.1 - 2.9e-24 85.0 1.7 3.1e-24 84.9 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2789) Lyase_1 PF00206.20 AFI84577.1 - 6.7e-98 327.9 1.4 7.9e-98 327.7 1.4 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AFI84577.1 - 2.9e-19 69.2 0.0 5.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus MbeD_MobD PF04899.12 AFI84577.1 - 0.54 10.4 3.4 1.5 9.0 3.4 1.8 1 0 0 1 1 1 0 MbeD/MobD like DUF1232 PF06803.12 AFI84578.1 - 5e-14 51.8 10.5 5e-14 51.8 10.5 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1232) MCPsignal PF00015.21 AFI84579.1 - 1.2e-38 132.6 15.5 1.2e-38 132.6 15.5 3.7 3 1 1 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 AFI84579.1 - 3.1e-27 94.8 1.2 1.6e-13 50.8 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 AFI84579.1 - 9.3e-27 93.1 0.2 2.8e-12 46.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AFI84579.1 - 1.7e-19 70.1 0.0 2e-09 37.7 0.0 2.9 3 0 0 3 3 2 2 PAS fold PAS PF00989.25 AFI84579.1 - 3.5e-16 59.2 0.3 2.7e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AFI84579.1 - 5.1e-06 26.4 0.0 0.031 14.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain DUF1664 PF07889.12 AFI84579.1 - 0.00025 21.1 15.6 0.27 11.3 1.1 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1664) PAS_11 PF14598.6 AFI84579.1 - 0.0018 18.4 0.1 0.31 11.2 0.1 2.5 2 0 0 2 2 2 1 PAS domain Cache_3-Cache_2 PF17201.4 AFI84579.1 - 0.0026 17.1 2.3 0.75 9.0 0.0 3.1 2 1 1 3 3 3 1 Cache 3/Cache 2 fusion domain DUF948 PF06103.11 AFI84579.1 - 0.0033 17.6 22.3 0.0043 17.3 3.0 4.4 4 1 1 5 5 5 1 Bacterial protein of unknown function (DUF948) sCache_3_3 PF17202.4 AFI84579.1 - 0.012 16.0 0.6 6.3 7.3 0.0 3.3 3 1 0 3 3 3 0 Single cache domain 3 NPV_P10 PF05531.12 AFI84579.1 - 0.033 14.6 18.9 2 8.9 5.0 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Dak2 PF02734.17 AFI84579.1 - 0.13 12.2 3.1 0.25 11.2 2.0 2.0 1 1 1 2 2 2 0 DAK2 domain Sec20 PF03908.13 AFI84579.1 - 0.24 11.3 14.8 0.26 11.2 2.9 4.5 5 0 0 5 5 4 0 Sec20 CENP-H PF05837.12 AFI84579.1 - 0.4 11.1 18.8 0.31 11.5 1.5 3.5 4 0 0 4 4 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 AFI84579.1 - 0.52 10.5 14.3 3.6 7.7 0.7 4.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 AFI84579.1 - 0.71 10.0 5.0 1.6 8.8 5.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MCU PF04678.13 AFI84579.1 - 1 9.4 11.1 3.9 7.5 2.5 2.9 2 1 1 3 3 3 0 Mitochondrial calcium uniporter DUF3958 PF13125.6 AFI84579.1 - 1.1 9.5 5.8 1.4 9.1 3.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF3958) FlgN PF05130.12 AFI84579.1 - 2.4 8.7 11.8 5.8 7.4 9.6 2.7 2 1 0 2 2 2 0 FlgN protein BLOC1_2 PF10046.9 AFI84579.1 - 3.7 7.9 16.5 0.45 10.8 2.7 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.6 AFI84579.1 - 4.2 7.8 13.9 0.62 10.5 4.9 3.7 3 1 1 4 4 4 0 Syntaxin-like protein Seryl_tRNA_N PF02403.22 AFI84579.1 - 5.4 7.3 14.1 0.84 9.9 0.8 3.6 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Sec34 PF04136.15 AFI84579.1 - 6.1 6.7 12.6 2.4 8.0 0.9 3.8 5 0 0 5 5 4 0 Sec34-like family DASH_Dad2 PF08654.10 AFI84579.1 - 6.2 7.3 16.9 6.1 7.3 4.1 3.8 3 1 1 4 4 3 0 DASH complex subunit Dad2 DUF2935 PF11155.8 AFI84579.1 - 7.1 7.0 8.6 99 3.3 4.2 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF745 PF05335.13 AFI84579.1 - 7.4 6.3 16.6 2.2 8.0 2.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PRKCSH-like PF12999.7 AFI84579.1 - 8.7 6.1 7.6 1.1 9.1 0.5 2.7 3 0 0 3 3 3 0 Glucosidase II beta subunit-like NMT1 PF09084.11 AFI84580.1 - 2.1e-15 57.2 0.0 3.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 AFI84580.1 - 7.9e-14 51.9 0.1 3.9e-13 49.7 0.1 1.9 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 AFI84580.1 - 6.3e-08 32.3 0.0 5.3e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 YhfZ_C PF14503.6 AFI84580.1 - 8.7e-05 22.2 0.1 0.00039 20.0 0.0 1.9 1 1 0 1 1 1 1 YhfZ C-terminal domain Phosphonate-bd PF12974.7 AFI84580.1 - 0.00013 21.7 0.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 AFI84580.1 - 0.077 12.6 0.1 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system LysR_substrate PF03466.20 AFI84580.1 - 0.087 12.2 0.0 6.4 6.1 0.0 2.1 2 0 0 2 2 2 0 LysR substrate binding domain HATPase_c PF02518.26 AFI84581.1 - 3.1e-21 76.0 0.0 6.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AFI84581.1 - 1.7e-15 57.1 0.1 4.4e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 AFI84581.1 - 2.5e-10 40.5 0.0 9.9e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AFI84581.1 - 9.9e-09 35.1 0.5 7.6e-08 32.3 0.0 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AFI84581.1 - 8.8e-07 29.1 0.0 2.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 PAS domain HAMP PF00672.25 AFI84581.1 - 4.5e-06 27.0 0.1 1.3e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 HAMP domain HPTransfase PF10090.9 AFI84581.1 - 0.0013 18.6 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain HATPase_c_5 PF14501.6 AFI84581.1 - 0.051 13.5 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 GHKL domain PAS PF00989.25 AFI84581.1 - 0.064 13.3 0.1 0.58 10.2 0.0 2.3 1 1 1 2 2 2 0 PAS fold HATPase_c_2 PF13581.6 AFI84581.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS_4 PF08448.10 AFI84581.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold Lipase_GDSL PF00657.22 AFI84581.1 - 0.15 12.0 0.1 0.5 10.3 0.1 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase PsiE PF06146.12 AFI84582.1 - 4e-16 59.1 2.4 4e-16 59.1 2.4 2.0 2 0 0 2 2 2 1 Phosphate-starvation-inducible E DUF2339 PF10101.9 AFI84582.1 - 0.0016 17.1 0.8 0.0022 16.7 0.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) 60KD_IMP PF02096.20 AFI84582.1 - 0.63 9.9 6.3 0.73 9.7 6.3 1.3 1 1 0 1 1 1 0 60Kd inner membrane protein DUF4229 PF14012.6 AFI84582.1 - 3.3 7.9 9.2 2.6 8.2 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) NPR3 PF03666.13 AFI84583.1 - 0.0015 17.4 2.1 0.0015 17.4 2.1 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Anophelin PF10731.9 AFI84583.1 - 0.011 15.6 0.7 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Zn_peptidase PF04228.13 AFI84585.1 - 5.2e-119 397.0 0.1 5.8e-119 396.8 0.1 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Aspzincin_M35 PF14521.6 AFI84585.1 - 0.045 14.3 0.0 0.084 13.4 0.0 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Peptidase_M78 PF06114.13 AFI84585.1 - 0.067 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain Peptidase_M48 PF01435.18 AFI84585.1 - 2 8.2 5.4 13 5.5 0.0 2.4 1 1 1 2 2 2 0 Peptidase family M48 Fae PF08714.11 AFI84586.1 - 4.6e-61 205.4 0.7 5.2e-61 205.2 0.7 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Peptidase_S13 PF02113.15 AFI84587.1 - 2.5e-97 326.4 0.0 3.2e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 AFI84587.1 - 0.00016 21.3 0.4 0.0022 17.6 0.2 2.5 2 1 0 2 2 2 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 AFI84587.1 - 0.0029 17.1 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Voltage_CLC PF00654.20 AFI84588.1 - 0.028 13.7 2.0 0.03 13.6 2.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel SUR7 PF06687.12 AFI84588.1 - 0.083 12.5 2.6 0.12 12.0 2.6 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF5325 PF17259.2 AFI84588.1 - 0.16 11.9 9.7 0.73 9.7 2.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5325) DUF2937 PF11157.8 AFI84588.1 - 0.17 11.6 1.5 0.24 11.1 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF1418 PF07214.12 AFI84588.1 - 0.21 11.5 1.7 0.23 11.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF2207 PF09972.9 AFI84588.1 - 1.6 7.4 4.5 2 7.0 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 AFI84588.1 - 2.1 8.3 7.8 12 5.9 0.3 2.2 2 0 0 2 2 2 0 Syndecan domain Response_reg PF00072.24 AFI84590.1 - 6.7e-26 90.7 0.5 1e-25 90.1 0.5 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84590.1 - 2.6e-22 78.7 0.1 5.8e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF4118 PF13493.6 AFI84591.1 - 5.2e-26 90.5 13.6 1e-25 89.6 13.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AFI84591.1 - 9e-20 71.3 0.0 1.9e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84591.1 - 4.7e-16 58.6 2.7 2.2e-15 56.4 2.7 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AFI84591.1 - 2.7e-05 24.0 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AFI84591.1 - 0.00031 20.7 0.0 0.00078 19.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF2892 PF11127.8 AFI84591.1 - 0.14 12.2 3.8 0.45 10.6 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) JAKMIP_CC3 PF16034.5 AFI84591.1 - 0.51 10.2 2.7 0.3 11.0 0.7 1.5 2 0 0 2 2 2 0 JAKMIP CC3 domain TrkA_N PF02254.18 AFI84592.1 - 1.2e-51 173.8 4.0 6.7e-27 94.1 0.2 2.6 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 AFI84592.1 - 2e-23 82.0 2.2 2.4e-10 40.1 0.0 3.7 3 0 0 3 3 3 2 TrkA-C domain NAD_binding_7 PF13241.6 AFI84592.1 - 7.4e-12 45.6 1.4 3.7e-06 27.3 0.0 3.2 2 1 1 3 3 3 2 Putative NAD(P)-binding F420_oxidored PF03807.17 AFI84592.1 - 1.2e-09 38.6 3.0 0.00085 19.9 0.0 3.3 3 2 1 4 4 2 2 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AFI84592.1 - 1.5e-08 35.0 3.0 0.00016 21.9 0.2 2.6 2 1 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AFI84592.1 - 1.9e-07 31.3 1.0 0.006 16.6 0.1 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AFI84592.1 - 2.6e-07 30.4 1.7 0.00049 19.8 0.0 3.0 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 AFI84592.1 - 4.5e-07 30.3 0.4 0.00059 20.3 0.1 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AFI84592.1 - 4.5e-07 29.9 0.2 0.00032 20.6 0.1 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 AFI84592.1 - 8.1e-06 25.9 0.1 0.039 13.9 0.0 2.6 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 AFI84592.1 - 1e-05 24.9 2.1 0.00015 21.1 0.2 2.3 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 AFI84592.1 - 1.7e-05 24.2 0.1 0.036 13.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 AFI84592.1 - 3.1e-05 23.7 2.8 0.031 13.8 0.1 2.6 3 0 0 3 3 2 2 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.14 AFI84592.1 - 6.7e-05 22.5 0.1 0.0014 18.2 0.0 2.9 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 AFI84592.1 - 8.8e-05 23.0 0.6 0.022 15.2 0.0 2.6 2 1 0 2 2 2 1 XdhC Rossmann domain Epimerase PF01370.21 AFI84592.1 - 0.00013 21.5 0.7 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI84592.1 - 0.00022 20.7 0.6 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 AFI84592.1 - 0.00025 21.2 0.6 0.11 12.7 0.0 2.8 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AFI84592.1 - 0.00053 19.4 0.1 0.48 9.8 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 AFI84592.1 - 0.00079 18.9 0.2 0.73 9.3 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_8 PF13450.6 AFI84592.1 - 0.0008 19.6 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GFO_IDH_MocA PF01408.22 AFI84592.1 - 0.0016 19.3 1.2 0.54 11.1 0.1 2.8 3 0 0 3 3 2 1 Oxidoreductase family, NAD-binding Rossmann fold DAO PF01266.24 AFI84592.1 - 0.0024 17.5 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Gp_dh_N PF00044.24 AFI84592.1 - 0.0038 17.5 0.8 0.84 10.0 0.1 2.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PglD_N PF17836.1 AFI84592.1 - 0.005 17.4 4.1 1.8 9.3 0.1 3.2 3 0 0 3 3 3 2 PglD N-terminal domain HI0933_like PF03486.14 AFI84592.1 - 0.009 14.8 0.1 0.08 11.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein DapB_N PF01113.20 AFI84592.1 - 0.014 15.5 2.3 2 8.6 0.0 3.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus AdoHcyase_NAD PF00670.21 AFI84592.1 - 0.029 14.4 1.3 0.27 11.3 0.1 2.8 3 1 1 4 4 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 AFI84592.1 - 0.031 13.5 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain ELFV_dehydrog PF00208.21 AFI84592.1 - 0.08 12.6 0.2 0.67 9.6 0.1 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LysE PF01810.18 AFI84593.1 - 5.7e-33 114.0 12.4 7.3e-33 113.7 12.4 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 AFI84593.1 - 0.00039 20.1 8.9 0.0016 18.1 8.9 1.9 1 1 0 1 1 1 1 Integral membrane protein TerC family Cytochrom_B558a PF05038.13 AFI84593.1 - 0.024 14.2 1.8 0.036 13.6 1.8 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Abhydrolase_9_N PF15420.6 AFI84593.1 - 0.079 12.9 5.3 1.3 9.0 0.5 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DLH PF01738.18 AFI84598.1 - 5.8e-36 124.1 0.2 6.5e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AFI84598.1 - 5.1e-10 39.2 3.4 4.1e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 AFI84598.1 - 5.9e-06 26.4 0.2 0.0052 16.7 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AFI84598.1 - 9.2e-05 21.8 1.1 0.0015 17.9 0.5 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 AFI84598.1 - 0.00015 21.6 0.3 0.00025 20.8 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 AFI84598.1 - 0.039 14.5 0.0 0.048 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AFI84598.1 - 0.053 13.2 0.2 0.11 12.1 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold AbiEi_3 PF11459.8 AFI84600.1 - 0.027 14.2 0.5 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Peptidase_S49_N PF08496.10 AFI84600.1 - 0.05 13.7 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Trp_repressor PF01371.19 AFI84601.1 - 0.061 13.5 2.4 0.19 11.9 1.4 2.3 1 1 1 2 2 2 0 Trp repressor protein HRG PF16954.5 AFI84601.1 - 0.061 13.7 0.9 5.4 7.5 0.3 2.4 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Sigma_reg_N PF13800.6 AFI84601.1 - 0.092 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4381 PF14316.6 AFI84601.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4381) TPR_1 PF00515.28 AFI84601.1 - 0.57 10.1 5.4 4.9 7.1 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Ribosomal_L16 PF00252.18 AFI84601.1 - 3.4 7.7 5.5 8 6.5 0.4 3.5 2 1 0 3 3 3 0 Ribosomal protein L16p/L10e FRB_dom PF08771.11 AFI84601.1 - 6.8 7.2 14.0 1 9.8 0.3 4.0 1 1 2 4 4 4 0 FKBP12-rapamycin binding domain TPR_8 PF13181.6 AFI84601.1 - 8.7 6.8 12.5 13 6.3 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat PEGA PF08308.11 AFI84602.1 - 7e-37 125.2 8.4 1.7e-13 50.2 0.5 5.3 3 2 2 5 5 5 4 PEGA domain FGE-sulfatase PF03781.16 AFI84602.1 - 2.7e-33 115.7 0.6 2.2e-31 109.4 0.6 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 CarboxypepD_reg PF13620.6 AFI84602.1 - 2.1e-10 40.7 4.1 0.0034 17.6 0.1 5.7 5 1 0 5 5 5 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 AFI84602.1 - 4.8e-06 26.5 2.7 0.84 9.7 0.0 5.2 4 1 2 6 6 6 2 CarboxypepD_reg-like domain DUF1236 PF06823.12 AFI84602.1 - 0.1 12.5 0.1 2 8.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1236) MotA_ExbB PF01618.16 AFI84604.1 - 2.7e-17 62.7 0.1 2.7e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family NVEALA PF14055.6 AFI84604.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.5 3 0 0 3 3 3 0 NVEALA protein TerC PF03741.16 AFI84604.1 - 0.39 10.4 5.1 11 5.7 5.1 2.5 1 1 0 1 1 1 0 Integral membrane protein TerC family Saf_2TM PF18303.1 AFI84604.1 - 0.42 10.2 3.3 0.24 11.0 0.2 2.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain VWA_2 PF13519.6 AFI84605.1 - 8.4e-10 39.3 0.2 8.4e-10 39.3 0.2 2.0 2 1 0 2 2 1 1 von Willebrand factor type A domain HemX PF04375.14 AFI84605.1 - 3.2e-05 23.4 5.7 3.2e-05 23.4 5.7 1.6 1 1 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase MscS_porin PF12795.7 AFI84605.1 - 4.6e-05 23.1 15.7 4.6e-05 23.1 15.7 1.5 2 0 0 2 2 1 1 Mechanosensitive ion channel porin domain Spc7 PF08317.11 AFI84605.1 - 0.00014 20.9 9.5 0.00014 20.9 9.5 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein APG6_N PF17675.1 AFI84605.1 - 0.0012 19.4 5.7 0.0012 19.4 5.7 1.7 2 0 0 2 2 1 1 Apg6 coiled-coil region LMBR1 PF04791.16 AFI84605.1 - 0.0047 15.9 2.7 0.0063 15.5 2.7 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein FPP PF05911.11 AFI84605.1 - 0.0063 14.8 6.9 0.0063 14.8 6.9 1.7 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 AFI84605.1 - 0.01 15.2 9.3 0.01 15.2 9.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 AFI84605.1 - 0.014 15.9 8.2 0.025 15.1 8.2 1.5 1 0 0 1 1 1 0 Fez1 DHR10 PF18595.1 AFI84605.1 - 0.014 15.4 7.7 0.014 15.4 7.7 2.3 2 1 1 3 3 2 0 Designed helical repeat protein 10 domain DUF1043 PF06295.12 AFI84605.1 - 0.023 14.7 2.3 0.023 14.7 2.3 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1043) VWA PF00092.28 AFI84605.1 - 0.033 14.5 3.7 0.036 14.3 0.6 2.5 2 1 0 2 2 1 0 von Willebrand factor type A domain HrpB7 PF09486.10 AFI84605.1 - 0.039 14.4 3.3 0.085 13.2 3.3 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF2201 PF09967.9 AFI84605.1 - 0.039 14.1 0.3 9.2 6.4 0.0 2.7 1 1 1 2 2 2 0 VWA-like domain (DUF2201) XhlA PF10779.9 AFI84605.1 - 0.041 14.1 1.0 0.041 14.1 1.0 3.6 3 0 0 3 3 3 0 Haemolysin XhlA DUF4201 PF13870.6 AFI84605.1 - 0.092 12.5 11.2 1.2 8.8 8.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) PspA_IM30 PF04012.12 AFI84605.1 - 0.13 11.9 10.2 0.018 14.6 6.2 1.6 2 0 0 2 2 1 0 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 AFI84605.1 - 0.19 12.0 14.2 0.025 14.8 9.8 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.8 AFI84605.1 - 0.23 10.8 11.8 0.36 10.2 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TMF_TATA_bd PF12325.8 AFI84605.1 - 0.27 11.5 15.8 0.32 11.2 9.8 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4763 PF15960.5 AFI84605.1 - 0.51 9.6 9.7 0.14 11.5 5.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) SPATA24 PF15175.6 AFI84605.1 - 0.54 10.1 11.8 0.1 12.5 6.9 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 ADIP PF11559.8 AFI84605.1 - 0.6 10.2 16.8 0.098 12.7 10.5 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 AFI84605.1 - 0.64 10.3 9.1 0.24 11.7 4.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain TMPIT PF07851.13 AFI84605.1 - 0.64 9.2 7.4 1.2 8.4 7.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 AFI84605.1 - 0.65 9.4 13.9 0.14 11.6 10.2 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 AFI84605.1 - 0.99 8.8 16.0 0.053 13.0 10.6 1.5 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 AFI84605.1 - 1.4 9.3 10.1 2.1 8.8 6.1 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FliJ PF02050.16 AFI84605.1 - 2.3 8.5 16.1 6.7 7.0 10.3 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein Fib_alpha PF08702.10 AFI84605.1 - 2.3 8.4 13.0 0.57 10.4 8.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 AFI84605.1 - 3.3 7.8 14.0 0.37 10.9 9.1 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 AFI84605.1 - 4.1 7.7 16.2 0.37 11.1 11.5 1.6 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 AFI84605.1 - 4.6 7.0 10.1 8.7 6.1 10.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) GAS PF13851.6 AFI84605.1 - 5.1 6.4 16.8 2 7.7 8.4 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_3 PF13758.6 AFI84605.1 - 5.1 7.2 10.5 2.1 8.5 5.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit Exonuc_VII_L PF02601.15 AFI84605.1 - 6 6.3 13.0 9.4 5.7 13.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 AFI84605.1 - 7.4 6.4 20.0 0.38 10.5 6.1 2.8 2 1 1 3 3 2 0 Septum formation initiator TPR_MLP1_2 PF07926.12 AFI84605.1 - 9.5 6.3 19.4 3 7.9 12.9 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 AFI84606.1 - 0.013 16.0 5.1 0.027 15.0 5.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4164 PF13747.6 AFI84606.1 - 0.015 15.5 4.1 0.024 14.9 3.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3584 PF12128.8 AFI84606.1 - 0.032 11.8 1.4 0.042 11.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) VWA_2 PF13519.6 AFI84606.1 - 0.051 14.2 0.6 0.48 11.1 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 AFI84606.1 - 0.12 12.6 1.4 1.6 8.9 0.1 2.6 3 0 0 3 3 3 0 von Willebrand factor type A domain Herpes_UL6 PF01763.16 AFI84606.1 - 0.14 10.7 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Fzo_mitofusin PF04799.13 AFI84606.1 - 0.17 11.5 1.7 0.28 10.7 1.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region TMF_DNA_bd PF12329.8 AFI84606.1 - 0.44 10.6 12.0 0.19 11.8 5.7 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 AFI84606.1 - 0.66 10.2 6.1 0.52 10.6 3.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 AFI84606.1 - 1.3 8.9 9.8 1.1 9.1 2.6 2.9 2 1 1 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 AFI84606.1 - 4.1 7.6 7.2 1.3 9.2 1.3 2.8 3 0 0 3 3 3 0 Basic region leucine zipper CHASE2 PF05226.11 AFI84607.1 - 6.7e-16 58.8 0.0 1.3e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 CHASE2 domain Peptidase_M48 PF01435.18 AFI84608.1 - 3.4e-16 59.6 0.1 5e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 TPR_19 PF14559.6 AFI84608.1 - 0.001 19.5 0.2 0.0022 18.4 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2268 PF10026.9 AFI84608.1 - 0.0012 18.5 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) TPR_16 PF13432.6 AFI84608.1 - 0.023 15.4 0.1 0.067 13.9 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M78 PF06114.13 AFI84608.1 - 0.034 14.1 0.5 0.23 11.4 0.5 2.3 1 1 0 1 1 1 0 IrrE N-terminal-like domain Streptin-Immun PF11083.8 AFI84608.1 - 0.056 13.8 1.3 0.26 11.7 0.5 2.6 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Antimicrobial_2 PF08023.12 AFI84608.1 - 0.11 13.0 0.9 2.7 8.6 0.2 2.6 2 0 0 2 2 2 0 Frog antimicrobial peptide DLH PF01738.18 AFI84610.1 - 4.8e-30 104.7 0.0 5.6e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 AFI84610.1 - 5.6e-05 22.9 0.3 0.00088 18.9 0.2 2.5 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.11 AFI84610.1 - 0.00018 20.6 0.2 0.00028 20.0 0.2 1.4 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 AFI84610.1 - 0.0002 20.3 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 AFI84610.1 - 0.0059 16.1 0.6 0.079 12.4 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 AFI84610.1 - 0.0065 16.4 0.1 0.23 11.4 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AFI84610.1 - 0.038 13.3 0.1 5.2 6.3 0.1 2.4 1 1 1 2 2 2 0 Serine aminopeptidase, S33 NERD PF08378.11 AFI84611.1 - 2e-28 99.0 1.9 2e-28 99.0 1.9 1.5 2 0 0 2 2 2 1 Nuclease-related domain zf-C4_Topoisom PF01396.19 AFI84611.1 - 2.7e-12 46.3 0.8 5.8e-12 45.2 0.8 1.6 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger zf-GRF PF06839.12 AFI84611.1 - 0.0018 18.3 1.3 0.0035 17.4 1.3 1.5 1 0 0 1 1 1 1 GRF zinc finger zinc_ribbon_2 PF13240.6 AFI84611.1 - 0.027 14.2 0.7 0.072 12.8 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AFI84611.1 - 0.045 13.7 0.7 0.097 12.7 0.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PreAtp-grasp PF18604.1 AFI84611.1 - 0.058 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Pre ATP-grasp domain Lar_restr_allev PF14354.6 AFI84611.1 - 0.095 13.1 0.5 0.21 12.0 0.5 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar PhnA_Zn_Ribbon PF08274.12 AFI84611.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Ogr_Delta PF04606.12 AFI84611.1 - 0.13 12.3 0.3 0.41 10.7 0.1 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_L37ae PF01780.19 AFI84611.1 - 0.28 11.3 0.2 0.28 11.3 0.2 1.9 2 0 0 2 2 2 0 Ribosomal L37ae protein family EAL PF00563.20 AFI84612.1 - 2.4e-60 204.0 0.0 3.5e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 EAL domain PTS_EIIC PF02378.18 AFI84612.1 - 2.2e-19 69.7 21.4 4.2e-19 68.7 21.4 1.5 1 0 0 1 1 1 1 Phosphotransferase system, EIIC YrhC PF14143.6 AFI84612.1 - 0.4 10.8 1.9 2.5 8.3 1.9 2.4 1 0 0 1 1 1 0 YrhC-like protein DUF5640 PF18692.1 AFI84613.1 - 0.0011 18.9 0.3 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5640) DUF4923 PF16270.5 AFI84613.1 - 0.028 14.3 0.2 0.074 12.9 0.1 1.7 1 1 1 2 2 2 0 Lipocalin-like domain (DUF4923) DUF3874 PF12990.7 AFI84614.1 - 0.16 12.3 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Response_reg PF00072.24 AFI84615.1 - 2e-28 98.8 0.1 5.2e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AFI84615.1 - 8.9e-17 60.4 0.4 1.9e-16 59.4 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AFI84615.1 - 8.5e-05 22.1 0.1 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 AFI84615.1 - 0.002 18.1 0.0 1.4 9.1 0.0 2.4 1 1 1 2 2 2 2 Helix-turn-helix domain HTH_38 PF13936.6 AFI84615.1 - 0.0048 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AFI84615.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AFI84615.1 - 0.02 14.9 0.0 0.087 12.9 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Phage_terminase PF10668.9 AFI84615.1 - 0.029 14.4 0.0 0.085 12.9 0.0 1.8 2 0 0 2 2 1 0 Phage terminase small subunit Terminase_5 PF06056.12 AFI84615.1 - 0.03 14.2 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 AFI84615.1 - 0.03 14.1 0.4 0.064 13.1 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.6 AFI84615.1 - 0.037 14.5 0.2 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain SAM_DrpA PF18255.1 AFI84615.1 - 0.039 14.2 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain Sigma70_r4 PF04545.16 AFI84615.1 - 0.12 11.9 0.0 0.37 10.4 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 AFI84615.1 - 0.15 12.2 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HATPase_c PF02518.26 AFI84616.1 - 4.8e-07 30.3 0.2 3.6e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AFI84616.1 - 6.9e-07 29.3 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA_3 PF07730.13 AFI84616.1 - 2.4e-05 24.8 0.1 5.2e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase HATPase_c_3 PF13589.6 AFI84616.1 - 0.0007 19.4 1.3 0.00087 19.1 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase P22_AR_C PF10548.9 AFI84616.1 - 0.0013 18.9 0.6 4.4 7.6 0.0 3.1 2 1 1 3 3 3 2 P22AR C-terminal domain Stress-antifung PF01657.17 AFI84616.1 - 0.023 15.3 0.1 0.039 14.6 0.1 1.5 1 1 0 1 1 1 0 Salt stress response/antifungal AIP3 PF03915.13 AFI84616.1 - 0.025 13.7 0.8 0.04 13.0 0.8 1.4 1 0 0 1 1 1 0 Actin interacting protein 3 VirB8 PF04335.13 AFI84616.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 VirB8 protein DHDPS PF00701.22 AFI84617.1 - 4.2e-54 183.2 0.2 4.7e-54 183.0 0.2 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ALAD PF00490.21 AFI84617.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase FlpD PF02662.16 AFI84617.1 - 0.13 12.3 2.2 0.17 11.9 0.2 2.2 2 2 1 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit LysR_substrate PF03466.20 AFI84618.1 - 5.5e-23 81.4 0.0 1.3e-22 80.2 0.0 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AFI84618.1 - 2.3e-20 72.3 0.1 4.4e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LOH1CR12 PF10158.9 AFI84618.1 - 0.028 14.5 0.1 0.063 13.3 0.1 1.7 1 0 0 1 1 1 0 Tumour suppressor protein NnrS PF05940.12 AFI84619.1 - 1.4e-112 376.7 61.3 1.6e-112 376.6 61.3 1.0 1 0 0 1 1 1 1 NnrS protein Myc_target_1 PF15179.6 AFI84619.1 - 0.39 10.6 2.6 9.8 6.0 0.5 2.4 2 0 0 2 2 2 0 Myc target protein 1 HTHP PF11534.8 AFI84620.1 - 3.1e-33 114.0 0.5 3.9e-33 113.7 0.5 1.1 1 0 0 1 1 1 1 Hexameric tyrosine-coordinated heme protein (HTHP) NDK PF00334.19 AFI84620.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoside diphosphate kinase MarR PF01047.22 AFI84621.1 - 3.5e-13 49.3 0.0 7.3e-13 48.2 0.0 1.5 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 AFI84621.1 - 1.4e-08 34.8 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AFI84621.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AFI84621.1 - 1e-05 25.0 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 AFI84621.1 - 1.5e-05 25.4 0.0 6e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_45 PF14947.6 AFI84621.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.7 AFI84621.1 - 0.00016 21.7 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.6 AFI84621.1 - 0.00021 21.2 0.1 0.00053 19.9 0.0 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain PadR PF03551.14 AFI84621.1 - 0.00076 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Fe_dep_repress PF01325.19 AFI84621.1 - 0.001 19.2 0.1 0.0019 18.4 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AFI84621.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AFI84621.1 - 0.0022 17.8 0.0 0.022 14.7 0.0 2.4 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AFI84621.1 - 0.0035 17.3 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_5 PF01022.20 AFI84621.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family B-block_TFIIIC PF04182.12 AFI84621.1 - 0.017 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HxlR PF01638.17 AFI84621.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF3116 PF11313.8 AFI84621.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) HTH_29 PF13551.6 AFI84621.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AFI84621.1 - 0.15 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TniQ PF06527.11 AFI84622.1 - 2e-13 51.2 0.0 5.4e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 TniQ HTH_17 PF12728.7 AFI84622.1 - 0.0032 17.6 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain zf-C2H2_11 PF16622.5 AFI84622.1 - 0.39 10.5 6.1 1.1 9.0 6.1 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type DZR PF12773.7 AFI84622.1 - 3.1 7.9 9.5 19 5.4 5.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon TniB PF05621.11 AFI84623.1 - 3.8e-21 75.4 0.0 5.6e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AFI84623.1 - 8.3e-19 68.2 0.0 2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AFI84623.1 - 4.7e-08 33.5 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AFI84623.1 - 5.2e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI84623.1 - 1.6e-05 25.4 0.8 0.00016 22.1 0.8 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 AFI84623.1 - 2e-05 24.2 0.1 0.0087 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain Hpr_kinase_C PF07475.12 AFI84623.1 - 4.8e-05 23.0 0.2 8.9e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain ATPase PF06745.13 AFI84623.1 - 0.00014 21.3 1.5 0.13 11.6 0.3 2.2 1 1 1 2 2 2 2 KaiC NB-ARC PF00931.22 AFI84623.1 - 0.00046 19.5 0.4 0.0008 18.7 0.1 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 AFI84623.1 - 0.0013 18.9 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 AFI84623.1 - 0.0013 18.6 0.3 0.02 14.7 0.3 2.1 1 1 0 1 1 1 1 Bacterial dnaA protein ATPase_2 PF01637.18 AFI84623.1 - 0.0016 18.4 0.2 0.4 10.5 0.0 2.2 1 1 0 2 2 2 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 AFI84623.1 - 0.0058 16.4 0.1 0.015 15.0 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 AFI84623.1 - 0.0061 17.1 0.4 0.018 15.5 0.4 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFI84623.1 - 0.008 16.1 1.5 0.012 15.5 0.3 1.8 2 0 0 2 2 2 1 RsgA GTPase NTPase_1 PF03266.15 AFI84623.1 - 0.016 15.1 2.7 4.8 7.1 0.5 2.9 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 AFI84623.1 - 0.023 14.9 0.9 0.039 14.2 0.2 1.6 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 AFI84623.1 - 0.025 15.1 1.2 0.082 13.4 1.2 1.8 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 AFI84623.1 - 0.032 14.1 0.3 0.079 12.9 0.3 1.7 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 AFI84623.1 - 0.035 14.5 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 AFI84623.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AFI84623.1 - 0.066 13.5 1.2 0.52 10.6 1.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AFI84623.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AFI84623.1 - 0.087 12.5 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AFI84623.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 AFI84623.1 - 0.13 12.4 0.5 0.39 10.8 0.5 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 AFI84623.1 - 0.19 11.6 0.2 0.31 10.9 0.2 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase rve PF00665.26 AFI84624.1 - 4.5e-12 46.2 0.0 9.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AFI84624.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Mu transposase, C-terminal HTH_32 PF13565.6 AFI84624.1 - 0.011 16.3 1.0 0.021 15.5 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Tn7_Tnp_TnsA_N PF08722.11 AFI84625.1 - 0.00018 21.7 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 TnsA endonuclease N terminal Botulinum_HA-17 PF05588.11 AFI84626.1 - 0.00096 19.3 0.8 0.002 18.2 0.1 1.8 2 0 0 2 2 2 1 Clostridium botulinum HA-17 domain DUF3788 PF12663.7 AFI84626.1 - 0.038 14.0 0.2 0.076 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) AI-2E_transport PF01594.16 AFI84627.1 - 0.12 11.5 0.3 0.2 10.7 0.3 1.3 1 0 0 1 1 1 0 AI-2E family transporter ATPgrasp_YheCD PF14398.6 AFI84628.1 - 0.00093 18.5 0.0 0.0067 15.7 0.0 2.2 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AFI84628.1 - 0.0037 17.3 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_ST PF14397.6 AFI84628.1 - 0.19 11.0 0.0 1 8.6 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp HATPase_c PF02518.26 AFI84629.1 - 2.1e-23 82.9 0.0 8.6e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84629.1 - 5.1e-12 45.7 1.2 1.2e-11 44.5 0.3 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AFI84629.1 - 6.7e-07 29.6 0.1 2.4e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 AFI84629.1 - 0.00014 21.7 0.0 0.00053 19.9 0.0 2.0 2 0 0 2 2 2 1 GHKL domain SAP30_Sin3_bdg PF13867.6 AFI84629.1 - 0.08 13.3 0.3 0.21 12.0 0.3 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 CcmD PF04995.14 AFI84629.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Trans_reg_C PF00486.28 AFI84630.1 - 4.3e-26 90.8 0.0 7.8e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AFI84630.1 - 1.4e-25 89.7 0.0 1.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Cu-oxidase_3 PF07732.15 AFI84632.1 - 8.9e-40 135.4 4.4 4.8e-35 120.2 0.0 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 AFI84632.1 - 4.6e-34 117.9 0.1 1.8e-29 102.9 0.1 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AFI84632.1 - 3.3e-26 91.7 8.7 1e-23 83.6 1.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase TAT_signal PF10518.9 AFI84632.1 - 0.059 13.2 0.6 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Cupredoxin_1 PF13473.6 AFI84632.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Cupredoxin-like domain CopB PF05275.11 AFI84633.1 - 2.3e-71 239.7 0.4 2.7e-71 239.5 0.4 1.0 1 0 0 1 1 1 1 Copper resistance protein B precursor (CopB) Autotransporter PF03797.19 AFI84633.1 - 0.0015 18.3 0.1 0.015 15.0 0.0 2.4 1 1 1 2 2 2 1 Autotransporter beta-domain OMP_b-brl PF13505.6 AFI84633.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain AA_permease_2 PF13520.6 AFI84634.1 - 2.5e-30 105.7 43.5 4.6e-30 104.8 43.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AFI84634.1 - 3e-18 65.7 41.5 4.4e-18 65.1 41.4 1.3 1 1 0 1 1 1 1 Amino acid permease DUF305 PF03713.13 AFI84639.1 - 0.012 15.8 1.6 0.015 15.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) MukF_C PF17193.4 AFI84639.1 - 0.052 13.7 0.9 1.2 9.2 0.1 2.3 1 1 1 3 3 3 0 MukF C-terminal domain RPN13_C PF16550.5 AFI84639.1 - 0.06 13.5 0.1 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 UCH-binding domain EamA PF00892.20 AFI84640.1 - 5.9e-40 136.6 47.6 2.5e-20 73.0 18.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family ICMT PF04140.14 AFI84641.1 - 2.1e-06 28.0 0.1 4.2e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 AFI84641.1 - 7.9e-06 26.2 1.5 7.9e-06 26.2 1.5 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase TFIID_NTD2 PF04494.15 AFI84641.1 - 0.0089 16.3 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Pox_A14 PF05767.12 AFI84641.1 - 0.16 12.1 0.7 0.31 11.2 0.3 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF2663 PF10864.8 AFI84641.1 - 0.17 12.3 0.6 0.73 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF3290 PF11694.8 AFI84641.1 - 0.21 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2933 PF11666.8 AFI84642.1 - 0.056 13.5 3.7 0.052 13.6 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2933) DUF3169 PF11368.8 AFI84642.1 - 0.07 12.6 0.0 0.071 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Nmad5 PF18757.1 AFI84643.1 - 0.047 13.9 11.1 0.079 13.2 11.1 1.4 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 PepSY_2 PF13670.6 AFI84643.1 - 0.12 12.4 0.9 0.26 11.3 0.1 2.0 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain DUF2933 PF11666.8 AFI84644.1 - 2 8.5 7.9 3.6 7.7 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2933) E1-E2_ATPase PF00122.20 AFI84645.1 - 1.3e-51 174.7 0.8 1.3e-51 174.7 0.8 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AFI84645.1 - 1.4e-48 166.0 6.1 1.4e-48 166.0 6.1 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AFI84645.1 - 3.8e-11 43.3 1.7 1.2e-10 41.6 0.1 2.8 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AFI84645.1 - 9.4e-08 32.1 2.0 0.0009 19.1 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI84645.1 - 9.6e-07 29.4 0.2 4.9e-06 27.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AFI84645.1 - 0.094 12.8 0.2 0.42 10.7 0.2 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CCSMST1 PF15013.6 AFI84645.1 - 0.17 12.0 0.6 15 5.8 0.1 2.4 2 0 0 2 2 2 0 CCSMST1 family OEP PF02321.18 AFI84649.1 - 5.7e-26 91.5 25.7 4.9e-16 59.1 13.8 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_D23 PF16576.5 AFI84650.1 - 6.5e-71 237.9 0.3 1.1e-70 237.2 0.3 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion CusF_Ec PF11604.8 AFI84650.1 - 8.9e-32 108.9 0.1 2.1e-15 56.5 0.0 3.4 3 0 0 3 3 3 2 Copper binding periplasmic protein CusF HlyD_3 PF13437.6 AFI84650.1 - 2.7e-18 66.6 2.1 4.9e-16 59.4 0.1 3.9 3 1 1 4 4 4 1 HlyD family secretion protein HlyD_D4 PF16572.5 AFI84650.1 - 4.6e-15 55.2 0.3 1.3e-14 53.8 0.3 1.8 1 0 0 1 1 1 1 Long alpha hairpin domain of cation efflux system protein, CusB Biotin_lipoyl_2 PF13533.6 AFI84650.1 - 7.4e-06 25.7 0.1 0.017 15.0 0.0 3.0 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AFI84650.1 - 1.8e-05 24.5 0.1 0.0044 16.8 0.1 2.7 2 0 0 2 2 2 1 Biotin-requiring enzyme DUF1344 PF07076.11 AFI84650.1 - 3.8e-05 23.5 0.4 0.8 9.7 0.0 4.3 3 2 0 3 3 3 2 Protein of unknown function (DUF1344) HlyD PF00529.20 AFI84650.1 - 0.0011 18.7 0.8 0.017 15.0 0.8 2.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS BatD PF13584.6 AFI84650.1 - 0.0044 15.9 0.0 0.73 8.6 0.0 2.4 2 1 1 3 3 3 2 Oxygen tolerance ACR_tran PF00873.19 AFI84651.1 - 1.8e-235 784.1 6.5 2e-235 783.9 6.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family HMA PF00403.26 AFI84651.1 - 0.051 14.0 0.9 1.5 9.3 0.0 3.1 3 0 0 3 3 3 0 Heavy-metal-associated domain SecD_SecF PF02355.16 AFI84651.1 - 0.2 11.0 14.8 0.12 11.7 3.1 2.5 2 0 0 2 2 2 0 Protein export membrane protein Phage_holin_5_2 PF16079.5 AFI84651.1 - 1.3 9.4 4.9 1.1 9.6 2.3 2.4 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V CusF_Ec PF11604.8 AFI84652.1 - 4.5e-25 87.4 0.1 6.6e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF TetR_C_1 PF02909.17 AFI84652.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SANTA PF09133.10 AFI84653.1 - 0.033 14.7 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 SANTA (SANT Associated) MAGE PF01454.19 AFI84653.1 - 0.097 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 MAGE family AAA PF00004.29 AFI84654.1 - 6.6e-17 62.2 0.0 3.2e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI84654.1 - 7.6e-13 48.6 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AFI84654.1 - 2.1e-06 28.0 0.0 5.4e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AFI84654.1 - 2.8e-06 27.8 0.2 0.0046 17.4 0.0 2.6 1 1 0 2 2 2 2 AAA ATPase domain AAA_3 PF07726.11 AFI84654.1 - 4.5e-05 23.3 0.0 0.00013 21.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AFI84654.1 - 7.1e-05 23.1 0.1 0.0029 17.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AFI84654.1 - 0.00015 21.5 0.0 0.00074 19.3 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 AFI84654.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AFI84654.1 - 0.0016 18.4 0.0 0.094 12.6 0.0 2.4 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 AFI84654.1 - 0.0022 17.4 0.1 0.0047 16.3 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 AFI84654.1 - 0.0044 17.6 0.1 0.068 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AFI84654.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 AFI84654.1 - 0.0079 16.4 0.1 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain ALMS_motif PF15309.6 AFI84654.1 - 0.015 15.8 0.9 0.029 14.8 0.9 1.4 1 0 0 1 1 1 0 ALMS motif RNA_helicase PF00910.22 AFI84654.1 - 0.028 14.8 0.0 0.063 13.7 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.18 AFI84654.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_7 PF12775.7 AFI84654.1 - 0.1 12.1 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 AFI84654.1 - 0.11 12.4 0.2 17 5.2 0.0 3.0 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea TsaE PF02367.17 AFI84654.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AFI84654.1 - 0.14 11.8 0.2 2.2 8.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Metallophos PF00149.28 AFI84656.1 - 6.7e-12 46.3 2.6 1e-11 45.7 2.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AFI84656.1 - 5.2e-11 43.0 3.3 6.4e-09 36.2 3.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThiF PF00899.21 AFI84657.1 - 3.2e-21 75.8 0.0 3.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 AFI84657.1 - 0.002 18.2 0.0 0.005 16.9 0.0 1.6 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AFI84657.1 - 0.017 15.4 0.1 0.041 14.1 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AFI84657.1 - 0.019 15.4 0.0 0.067 13.6 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 AFI84657.1 - 0.02 14.5 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 AFI84657.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1188 PF06690.11 AFI84657.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1188) 3HCDH_N PF02737.18 AFI84657.1 - 0.24 11.2 0.2 0.78 9.6 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SMODS PF18144.1 AFI84659.1 - 2.1e-07 31.3 0.3 4.6e-05 23.6 0.3 2.5 1 1 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain TUG-UBL1 PF11470.8 AFI84659.1 - 0.0065 16.7 0.1 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 TUG ubiquitin-like domain Acetyltransf_13 PF13880.6 AFI84659.1 - 0.042 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase SAVED PF18145.1 AFI84660.1 - 8.4e-41 139.9 0.1 1.7e-40 138.9 0.1 1.5 1 1 0 1 1 1 1 SMODS-associated and fused to various effectors sensor domain HNH_2 PF13391.6 AFI84660.1 - 0.00067 19.7 0.2 0.0055 16.8 0.1 2.3 2 0 0 2 2 2 1 HNH endonuclease LEA_2 PF03168.13 AFI84661.1 - 0.15 12.6 0.0 11 6.7 0.0 2.0 1 1 1 2 2 2 0 Late embryogenesis abundant protein ABC_membrane PF00664.23 AFI84662.1 - 2.4e-55 188.1 15.4 3.4e-55 187.6 15.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AFI84662.1 - 8.1e-38 130.0 0.0 1.4e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Peptidase_C39 PF03412.15 AFI84662.1 - 2.4e-11 43.6 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family SMC_N PF02463.19 AFI84662.1 - 8.5e-06 25.4 0.4 0.0024 17.4 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AFI84662.1 - 0.0019 17.9 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 AFI84662.1 - 0.017 14.1 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 AFI84662.1 - 0.02 14.7 0.3 0.34 10.7 0.2 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AFI84662.1 - 0.022 15.1 0.0 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 AFI84662.1 - 0.058 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 AFI84662.1 - 0.059 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 AFI84662.1 - 0.091 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 AFI84662.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 AFI84662.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 AFI84662.1 - 0.15 12.3 0.3 0.91 9.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AFI84662.1 - 0.2 11.3 0.1 0.53 10.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain HlyD_3 PF13437.6 AFI84663.1 - 3.3e-16 59.9 4.0 7.4e-15 55.6 0.1 3.0 3 1 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 AFI84663.1 - 1.1e-08 34.6 17.7 0.00028 20.2 11.2 3.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AFI84663.1 - 1.2e-08 34.7 0.9 6.5e-07 29.1 0.2 3.5 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD PF00529.20 AFI84663.1 - 5e-06 26.3 0.1 7.2e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AFI84663.1 - 0.0025 17.6 1.1 0.046 13.6 0.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AFI84663.1 - 0.0046 16.7 0.2 0.31 10.8 0.0 3.0 2 1 1 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 AFI84663.1 - 0.064 13.5 0.1 0.64 10.3 0.0 2.7 2 1 0 2 2 2 0 Peptidase family M23 Rotamase_2 PF13145.6 AFI84663.1 - 0.44 11.4 5.0 0.53 11.1 3.6 1.8 1 1 1 2 2 2 0 PPIC-type PPIASE domain FliJ PF02050.16 AFI84663.1 - 9.8 6.4 26.5 0.46 10.7 7.8 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein HemolysinCabind PF00353.19 AFI84665.1 - 1.1e-181 587.7 691.8 3.6e-10 39.6 12.6 42.5 27 13 18 46 46 46 42 RTX calcium-binding nonapeptide repeat (4 copies) HCBP_related PF06594.11 AFI84665.1 - 4.7e-65 215.3 89.3 2.1e-10 40.4 2.0 16.0 14 0 0 14 14 14 11 Haemolysin-type calcium binding protein related domain He_PIG PF05345.12 AFI84665.1 - 5.2e-36 122.6 39.0 2e-09 37.5 0.8 5.7 5 0 0 5 5 5 4 Putative Ig domain Big_9 PF17963.1 AFI84665.1 - 9.6e-05 23.1 9.8 9.6e-05 23.1 9.8 7.7 6 1 1 7 7 7 3 Bacterial Ig domain RTX_C PF08339.10 AFI84665.1 - 0.0023 18.0 0.3 0.78 9.8 0.1 4.7 4 1 1 5 5 5 1 RTX C-terminal domain Sarcoglycan_2 PF05510.13 AFI84665.1 - 0.0042 15.9 0.2 7.5 5.2 0.0 3.2 1 1 2 3 3 3 2 Sarcoglycan alpha/epsilon DUF4625 PF15418.6 AFI84665.1 - 0.0075 16.5 0.9 31 4.8 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4625) PKD PF00801.20 AFI84665.1 - 0.25 11.2 2.1 3.5 7.5 0.1 3.5 3 0 0 3 3 3 0 PKD domain AAA_21 PF13304.6 AFI84667.1 - 2.9e-14 53.6 5.5 2e-12 47.5 5.5 2.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AFI84667.1 - 1.4e-09 38.2 10.2 5.1e-08 33.0 0.3 3.3 3 2 1 4 4 4 2 AAA ATPase domain ABC_tran PF00005.27 AFI84667.1 - 0.0019 18.7 0.0 0.0073 16.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter DUF2813 PF11398.8 AFI84667.1 - 0.016 14.5 0.6 0.032 13.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) HNH_5 PF14279.6 AFI84668.1 - 0.0047 16.7 0.8 0.018 14.9 0.8 2.0 1 1 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 AFI84668.1 - 0.029 14.3 2.1 0.1 12.5 0.2 2.8 2 1 0 2 2 2 0 HNH endonuclease SesA PF17107.5 AFI84668.1 - 0.066 13.4 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HNH PF01844.23 AFI84668.1 - 0.081 13.1 1.7 0.26 11.5 1.7 1.9 1 1 0 1 1 1 0 HNH endonuclease zf-ISL3 PF14690.6 AFI84668.1 - 0.2 12.4 1.1 9 7.0 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HEPN_LA2681 PF18733.1 AFI84669.1 - 9.4e-82 273.4 5.5 1.9e-81 272.4 5.5 1.5 1 0 0 1 1 1 1 LA2681-like HEPN TPR_2 PF07719.17 AFI84669.1 - 0.00025 20.9 0.0 0.0011 18.9 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84669.1 - 0.00037 20.2 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 AFI84669.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat HEPN_Cthe2314 PF18730.1 AFI84669.1 - 0.011 15.8 6.6 0.04 14.0 6.6 2.0 1 1 0 1 1 1 0 Cthe_2314-like HEPN COX2 PF00116.20 AFI84669.1 - 0.07 13.0 0.3 0.97 9.3 0.0 2.6 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, periplasmic domain TPR_10 PF13374.6 AFI84669.1 - 0.19 11.7 0.4 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2384 PF09722.10 AFI84670.1 - 6.3e-10 38.9 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) HTH_11 PF08279.12 AFI84670.1 - 0.096 12.7 0.4 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 HTH domain HTH_17 PF12728.7 AFI84671.1 - 1.2e-08 35.0 0.0 0.31 11.3 0.0 5.3 5 0 0 5 5 5 3 Helix-turn-helix domain TniQ PF06527.11 AFI84671.1 - 3.2e-06 27.9 0.0 1e-05 26.3 0.0 1.9 2 0 0 2 2 2 1 TniQ AbiEi_4 PF13338.6 AFI84671.1 - 0.00011 22.3 0.0 0.56 10.4 0.0 4.3 4 0 0 4 4 4 2 Transcriptional regulator, AbiEi antitoxin MerR_1 PF13411.6 AFI84671.1 - 0.00031 20.7 0.0 0.0047 17.0 0.0 2.9 2 0 0 2 2 2 1 MerR HTH family regulatory protein TniB PF05621.11 AFI84672.1 - 2.9e-21 75.8 0.0 5.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AFI84672.1 - 1.1e-18 67.8 0.0 2.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AFI84672.1 - 0.00027 21.4 0.1 0.0054 17.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AFI84672.1 - 0.00028 20.6 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AFI84672.1 - 0.00095 18.8 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 AFI84672.1 - 0.0013 18.8 0.0 0.018 15.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI84672.1 - 0.0013 19.1 0.0 0.0071 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 AFI84672.1 - 0.0022 18.5 0.1 0.012 16.1 0.0 2.4 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 AFI84672.1 - 0.0032 17.4 1.2 0.0051 16.7 0.1 1.9 3 0 0 3 3 3 1 RsgA GTPase ATPase_2 PF01637.18 AFI84672.1 - 0.011 15.7 0.0 18 5.1 0.0 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 AFI84672.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AFI84672.1 - 0.014 15.9 1.6 0.21 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 AFI84672.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Ras family CR6_interact PF10147.9 AFI84672.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 AAA_7 PF12775.7 AFI84672.1 - 0.023 14.2 0.0 0.15 11.5 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region MCM PF00493.23 AFI84672.1 - 0.031 13.4 0.1 0.054 12.6 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain SMC_N PF02463.19 AFI84672.1 - 0.04 13.3 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain rve PF00665.26 AFI84673.1 - 1e-14 54.7 0.0 2.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AFI84673.1 - 2e-07 30.8 0.1 2.2e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 Mu transposase, C-terminal rve_3 PF13683.6 AFI84673.1 - 1.9e-05 24.4 0.4 0.0014 18.4 0.4 2.9 1 1 0 1 1 1 1 Integrase core domain Tn7_Tnp_TnsA_N PF08722.11 AFI84674.1 - 6.3e-05 23.1 0.0 0.00054 20.1 0.0 2.4 3 0 0 3 3 3 1 TnsA endonuclease N terminal HTH_18 PF12833.7 AFI84674.1 - 0.18 12.1 0.3 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 AFI84675.1 - 7.6e-11 41.9 0.0 1.1e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 AFI84675.1 - 8.2e-10 38.6 0.0 5.2e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 AFI84675.1 - 2.3e-07 31.1 0.0 5.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AFI84675.1 - 7.8e-05 23.0 0.0 0.00024 21.5 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_10 PF04967.12 AFI84675.1 - 0.02 14.7 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain GP3_package PF16677.5 AFI84675.1 - 0.028 14.6 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 DNA-packaging protein gp3 NUMOD1 PF07453.13 AFI84675.1 - 0.085 13.1 0.2 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 NUMOD1 domain N6_N4_Mtase PF01555.18 AFI84676.1 - 9.7e-11 41.8 0.1 0.00044 20.0 0.1 2.3 2 0 0 2 2 2 2 DNA methylase Methyltransf_15 PF09445.10 AFI84676.1 - 0.091 12.3 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase SAM_MT PF04445.13 AFI84676.1 - 0.099 12.0 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase UPF0020 PF01170.18 AFI84676.1 - 0.12 12.1 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Stork_head PF10264.9 AFI84676.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain AAA_23 PF13476.6 AFI84677.1 - 2.2e-09 38.1 1.8 2.2e-09 38.1 1.8 2.7 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 AFI84677.1 - 3.2e-05 23.5 2.4 0.013 14.9 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain EzrA PF06160.12 AFI84677.1 - 0.00026 19.3 1.3 0.00026 19.3 1.3 2.5 2 1 0 2 2 2 2 Septation ring formation regulator, EzrA AAA_29 PF13555.6 AFI84677.1 - 0.00027 20.6 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AFI84677.1 - 0.022 14.4 0.7 0.1 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AFI84677.1 - 0.025 15.1 2.5 0.078 13.5 0.0 2.9 3 2 0 3 3 3 0 ABC transporter Lebercilin PF15619.6 AFI84677.1 - 0.047 13.4 9.9 0.64 9.6 1.8 2.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RsgA_GTPase PF03193.16 AFI84677.1 - 0.051 13.5 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase Vinculin PF01044.19 AFI84677.1 - 0.06 11.6 1.6 0.094 10.9 1.6 1.2 1 0 0 1 1 1 0 Vinculin family Cytochrom_c3_2 PF14537.6 AFI84677.1 - 0.13 12.7 1.9 0.31 11.5 1.9 1.6 1 0 0 1 1 1 0 Cytochrome c3 Zn-ribbon_8 PF09723.10 AFI84677.1 - 0.27 11.4 1.2 0.71 10.0 1.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Occludin_ELL PF07303.13 AFI84677.1 - 1.6 9.5 15.6 12 6.7 0.9 4.5 4 1 0 4 4 4 0 Occludin homology domain Rab5-bind PF09311.11 AFI84677.1 - 3.4 7.0 11.0 0.3 10.4 1.3 2.9 2 1 0 3 3 3 0 Rabaptin-like protein Atg14 PF10186.9 AFI84677.1 - 4.9 6.1 13.5 0.055 12.6 0.6 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 AFI84677.1 - 9.6 6.7 21.6 4.7 7.7 3.6 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region rve PF00665.26 AFI84679.1 - 4.4e-18 65.6 0.0 1.9e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 AFI84679.1 - 0.0014 18.4 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 AFI84679.1 - 0.019 14.5 0.0 0.092 12.3 0.0 2.2 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.7 AFI84679.1 - 0.046 13.6 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 MarR family LuxQ-periplasm PF09308.10 AFI84679.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 LuxQ, periplasmic DUF4167 PF13763.6 AFI84679.1 - 0.087 13.0 0.1 3.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) IstB_IS21 PF01695.17 AFI84680.1 - 2.6e-54 183.6 0.2 3.5e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein IstB_IS21_ATP PF08483.11 AFI84680.1 - 9e-12 44.7 0.1 2.2e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding N-terminal PhoH PF02562.16 AFI84680.1 - 0.00022 20.7 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 AFI84680.1 - 0.00039 20.4 1.1 0.0022 17.9 0.1 2.4 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 AFI84680.1 - 0.0006 20.2 0.1 0.0012 19.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AFI84680.1 - 0.00073 19.8 3.1 0.0014 18.9 0.9 2.5 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 AFI84680.1 - 0.00075 19.5 0.2 0.0015 18.5 0.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 AFI84680.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 AFI84680.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AFI84680.1 - 0.0035 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 AFI84680.1 - 0.0039 17.6 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 AFI84680.1 - 0.0043 17.1 0.0 0.013 15.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 AFI84680.1 - 0.0047 17.4 0.0 0.0068 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AFI84680.1 - 0.0048 17.5 0.0 0.0096 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AFI84680.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 AFI84680.1 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Sigma54_activat PF00158.26 AFI84680.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ArsA_ATPase PF02374.15 AFI84680.1 - 0.015 14.5 0.1 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 Anion-transporting ATPase Microtub_bd PF16796.5 AFI84680.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding Sigma54_activ_2 PF14532.6 AFI84680.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 AFI84680.1 - 0.022 15.3 0.1 0.065 13.7 0.1 1.9 1 1 0 1 1 1 0 ABC transporter DNA_pol3_delta2 PF13177.6 AFI84680.1 - 0.028 14.2 0.3 1.7 8.4 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 AFI84680.1 - 0.049 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 AFI84680.1 - 0.05 13.4 0.2 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase PduV-EutP PF10662.9 AFI84680.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 AFI84680.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 AFI84680.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 AFI84680.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AFI84680.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Ribonuc_red_sm PF00268.21 AFI84681.1 - 8e-62 209.2 0.5 9.9e-62 208.9 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain EF-hand_7 PF13499.6 AFI84681.1 - 0.061 13.8 0.1 0.58 10.6 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair SARA PF11409.8 AFI84681.1 - 0.23 11.7 0.4 0.5 10.6 0.4 1.4 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Ribonuc_red_lgC PF02867.15 AFI84682.1 - 1.5e-182 607.8 0.0 2.5e-182 607.1 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 AFI84682.1 - 1.1e-30 106.0 3.1 5.1e-19 68.6 0.8 3.0 3 0 0 3 3 3 2 ATP cone domain Ribonuc_red_lgN PF00317.21 AFI84682.1 - 1.7e-22 79.2 0.2 6.1e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain MFS_1 PF07690.16 AFI84683.1 - 0.013 14.5 2.1 0.017 14.0 2.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MAF_flag10 PF01973.18 AFI84683.1 - 0.071 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 Phage_holin_3_6 PF07332.11 AFI84683.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ABC2_membrane_5 PF13346.6 AFI84683.1 - 0.38 10.3 5.0 0.54 9.8 5.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2975 PF11188.8 AFI84683.1 - 0.44 10.4 4.1 0.65 9.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Cyt_bd_oxida_I PF01654.17 AFI84684.1 - 1.2e-149 498.5 30.4 1.4e-149 498.3 30.4 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cyt_bd_oxida_II PF02322.15 AFI84685.1 - 5.4e-96 321.5 39.5 6.2e-96 321.3 39.5 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II E1-E2_ATPase PF00122.20 AFI84685.1 - 0.99 8.9 4.1 0.48 9.9 0.9 2.1 2 0 0 2 2 2 0 E1-E2 ATPase SieB PF14163.6 AFI84685.1 - 0.99 8.9 5.1 8.8 5.8 0.3 2.6 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF3188 PF11384.8 AFI84685.1 - 6.7 6.5 10.1 0.44 10.3 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) ABC_tran PF00005.27 AFI84686.1 - 1.3e-27 97.0 0.0 2.9e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AFI84686.1 - 7.7e-25 88.1 12.9 1e-24 87.7 12.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AFI84686.1 - 8.4e-08 31.9 0.1 9.5e-06 25.2 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AFI84686.1 - 8.8e-06 26.2 0.5 0.00031 21.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AFI84686.1 - 7.5e-05 22.7 0.5 0.048 13.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 AFI84686.1 - 0.0023 17.9 0.1 0.0049 16.8 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 AFI84686.1 - 0.0053 16.7 1.6 0.012 15.5 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 AFI84686.1 - 0.0062 16.8 0.3 0.025 14.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFI84686.1 - 0.014 15.3 0.1 0.041 13.8 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase SbcCD_C PF13558.6 AFI84686.1 - 0.021 15.0 0.2 0.61 10.4 0.1 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AFI84686.1 - 0.024 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 AFI84686.1 - 0.036 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AFI84686.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 AFI84686.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 AFI84686.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AFI84686.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AFI84686.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AFI84686.1 - 0.064 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AFI84686.1 - 0.08 13.5 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AFI84686.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 AFI84686.1 - 0.089 12.2 0.1 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AFI84686.1 - 0.11 12.6 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 AFI84686.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 AFI84686.1 - 0.23 12.0 0.0 0.51 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF373 PF04123.13 AFI84686.1 - 5 6.5 11.8 2.8 7.3 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) ABC_tran PF00005.27 AFI84687.1 - 1.3e-26 93.8 0.4 7.3e-26 91.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 AFI84687.1 - 1.8e-06 27.8 6.7 1.8e-06 27.8 6.7 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 AFI84687.1 - 0.00043 20.2 0.2 0.29 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AFI84687.1 - 0.00048 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI84687.1 - 0.00082 19.8 1.1 0.0075 16.7 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 AFI84687.1 - 0.0085 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AFI84687.1 - 0.011 15.6 0.1 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 AFI84687.1 - 0.089 11.8 2.2 0.16 11.0 0.1 2.1 2 1 0 2 2 2 0 Type II/IV secretion system protein COQ7 PF03232.13 AFI84687.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 SbcCD_C PF13558.6 AFI84687.1 - 0.13 12.5 1.8 0.28 11.5 0.1 2.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 AFI84687.1 - 0.17 12.1 1.7 0.22 11.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AFI84687.1 - 0.5 10.8 0.1 0.5 10.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain SLATT_3 PF18184.1 AFI84687.1 - 1.4 9.0 4.4 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 EI24 PF07264.11 AFI84687.1 - 1.7 8.9 15.1 26 5.0 14.8 2.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) ShlB PF03865.13 AFI84688.1 - 6e-102 341.3 11.7 7.3e-102 341.0 11.7 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AFI84688.1 - 6.6e-18 64.3 0.2 2.4e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA_3 PF17287.2 AFI84688.1 - 3.5e-17 61.6 0.1 6.7e-17 60.7 0.1 1.5 1 0 0 1 1 1 1 POTRA domain Fil_haemagg_2 PF13332.6 AFI84689.1 - 1.2e-51 175.2 80.1 3.3e-45 154.3 36.2 10.5 4 3 7 12 12 12 8 Hemagglutinin repeat Haemagg_act PF05860.13 AFI84689.1 - 6.5e-33 113.2 6.1 6.5e-33 113.2 6.1 4.6 3 0 0 3 3 3 1 haemagglutination activity domain DDE_Tnp_1_3 PF13612.6 AFI84691.1 - 1.9e-77 258.6 0.0 2.7e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI84691.1 - 7.9e-23 81.2 0.1 1.1e-21 77.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI84691.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain YqfQ PF14181.6 AFI84692.1 - 0.13 12.5 5.1 0.057 13.6 2.5 1.7 2 0 0 2 2 2 0 YqfQ-like protein SmpA_OmlA PF04355.13 AFI84694.1 - 0.0015 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family DUF3192 PF11399.8 AFI84694.1 - 0.0037 17.2 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3192) DUF2845 PF11006.8 AFI84694.1 - 0.028 14.5 0.4 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) TA_inhibitor PF17574.2 AFI84694.1 - 0.055 13.5 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Inhibitor of toxin/antitoxin system (Gp4.5) TPR_12 PF13424.6 AFI84696.1 - 1.1e-08 35.3 0.4 1.5e-08 34.8 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84696.1 - 8.9e-08 31.7 2.8 0.0088 16.1 2.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AFI84696.1 - 2e-05 25.0 0.2 3.4e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 AFI84696.1 - 0.00013 21.7 0.3 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 AFI84696.1 - 0.00057 19.4 0.1 0.00066 19.1 0.1 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 AFI84696.1 - 0.0057 16.4 2.9 0.76 9.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AFI84696.1 - 0.011 15.7 0.6 0.56 10.4 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 AFI84696.1 - 0.014 15.1 0.7 0.018 14.8 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 AFI84696.1 - 0.037 14.7 0.0 0.062 13.9 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat SfsA_N PF17746.1 AFI84696.1 - 0.086 13.0 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 SfsA N-terminal OB domain PIN PF01850.21 AFI84697.1 - 6.3e-17 62.2 0.0 7.8e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 PIN domain DUF5615 PF18480.1 AFI84697.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5615) PIN_2 PF10130.9 AFI84697.1 - 0.0025 18.0 0.2 0.0055 16.9 0.2 1.8 1 1 0 1 1 1 1 PIN domain PIN_12 PF16289.5 AFI84697.1 - 0.0049 17.4 0.0 0.0065 17.0 0.0 1.3 1 1 0 1 1 1 1 PIN domain DUF2938 PF11158.8 AFI84698.1 - 5.9e-16 58.3 0.6 6.4e-16 58.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) MerR_1 PF13411.6 AFI84699.1 - 3.2e-15 56.0 0.0 5e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AFI84699.1 - 1.1e-11 45.0 0.6 2e-11 44.2 0.6 1.4 1 0 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 AFI84699.1 - 3.4e-11 42.7 0.3 6.3e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_3 PF01381.22 AFI84699.1 - 0.0027 17.7 0.1 0.12 12.4 0.1 2.8 1 1 2 3 3 3 1 Helix-turn-helix HTH_23 PF13384.6 AFI84699.1 - 0.0064 16.3 0.9 2.2 8.2 0.1 2.6 3 0 0 3 3 3 2 Homeodomain-like domain HTH_31 PF13560.6 AFI84699.1 - 0.0086 16.4 0.3 0.21 12.0 0.1 2.5 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.6 AFI84699.1 - 0.0095 15.7 0.4 0.12 12.2 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 AFI84699.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AbiEi_4 PF13338.6 AFI84699.1 - 0.025 14.7 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_IclR PF09339.10 AFI84699.1 - 0.042 13.7 0.2 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain Bac_luciferase PF00296.20 AFI84700.1 - 4.6e-37 128.1 2.0 2.5e-36 125.7 2.0 1.8 1 1 0 1 1 1 1 Luciferase-like monooxygenase Glyco_tranf_2_4 PF13704.6 AFI84700.1 - 0.19 12.3 0.0 0.49 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 UPF0061 PF02696.14 AFI84701.1 - 9.2e-73 245.6 0.0 1.2e-72 245.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Bax1-I PF01027.20 AFI84702.1 - 5.9e-42 143.8 30.4 7.3e-42 143.5 30.4 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 AFI84702.1 - 0.0019 17.8 20.7 0.014 14.9 20.8 1.9 1 1 0 1 1 1 1 Bax inhibitor 1 like DUF2686 PF10887.8 AFI84702.1 - 0.055 12.4 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Mob_synth_C PF06463.13 AFI84704.1 - 2.7e-39 134.0 0.0 7.8e-39 132.5 0.0 1.8 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AFI84704.1 - 6.8e-24 85.1 0.0 1.1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AFI84704.1 - 0.00066 20.0 0.0 0.004 17.4 0.0 2.1 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AFI84704.1 - 0.002 18.2 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain CVNH PF08881.10 AFI84704.1 - 0.044 14.5 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 CVNH domain COE1_HLH PF16423.5 AFI84704.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain FdhD-NarQ PF02634.15 AFI84705.1 - 2.2e-72 243.6 0.0 2.5e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family MazG PF03819.17 AFI84706.1 - 3.1e-10 40.1 0.2 5.1e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 AFI84706.1 - 6.1e-05 23.4 0.1 9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 AFI84706.1 - 0.0041 17.4 0.1 0.0083 16.4 0.1 1.6 1 1 0 1 1 1 1 MazG-like family BshC PF10079.9 AFI84706.1 - 0.023 13.5 0.4 0.026 13.3 0.4 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC S4 PF01479.25 AFI84707.1 - 9.9e-14 50.8 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain AMP-binding PF00501.28 AFI84708.1 - 4.8e-96 321.9 0.1 5.7e-96 321.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AFI84708.1 - 8e-27 94.0 0.4 8e-27 94.0 0.4 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AFI84708.1 - 1.2e-22 79.6 0.7 7.5e-22 77.0 0.8 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 AFI84708.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Aldedh PF00171.22 AFI84709.1 - 2.7e-163 543.8 0.1 3.1e-163 543.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 AFI84709.1 - 0.046 12.8 0.0 0.097 11.7 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) AraC_N PF06719.13 AFI84710.1 - 6.1e-25 87.6 0.0 8.7e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 AFI84710.1 - 1.5e-22 79.6 0.2 2.5e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AFI84710.1 - 1.2e-19 69.9 0.2 2.3e-08 33.9 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family VHP PF02209.19 AFI84710.1 - 0.19 11.8 0.2 9.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Villin headpiece domain Bac_surface_Ag PF01103.23 AFI84711.1 - 1e-27 97.5 5.2 1.2e-26 94.1 5.1 2.1 1 1 0 1 1 1 1 Surface antigen POTRA_TamA_1 PF17243.2 AFI84711.1 - 3.2e-15 56.0 0.1 7.1e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 POTRA domain TamA domain 1 POTRA PF07244.15 AFI84711.1 - 3.7e-13 49.9 0.2 5.5e-05 23.7 0.0 3.6 4 0 0 4 4 4 3 Surface antigen variable number repeat DUF2490 PF10677.9 AFI84711.1 - 0.078 12.9 0.9 0.33 10.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2490) TamB PF04357.13 AFI84712.1 - 2.2e-60 204.9 26.2 1.6e-59 202.1 1.6 7.1 4 2 4 9 9 9 3 TamB, inner membrane protein subunit of TAM complex PmrD PF11183.8 AFI84712.1 - 0.15 12.2 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD zf-dskA_traR PF01258.17 AFI84713.1 - 1e-11 44.6 2.2 1.5e-11 44.0 2.2 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger P53_tetramer PF07710.11 AFI84713.1 - 0.047 13.0 1.4 0.11 11.9 1.4 1.5 1 0 0 1 1 1 0 P53 tetramerisation motif HAD_2 PF13419.6 AFI84714.1 - 8.6e-26 91.1 0.0 1.2e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AFI84714.1 - 1e-18 68.4 0.0 2.3e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI84714.1 - 0.00093 19.6 0.5 0.0018 18.7 0.5 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI84714.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 AFI84714.1 - 0.018 14.9 0.1 5.1 6.9 0.0 2.5 2 1 1 3 3 3 0 Acid Phosphatase Aminotran_1_2 PF00155.21 AFI84715.1 - 7.8e-54 183.2 0.0 8.9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AFI84715.1 - 3.4e-09 35.7 0.0 5.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AFI84715.1 - 1.1e-07 31.2 0.0 2.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 AFI84715.1 - 1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Allinase Fer2_BFD PF04324.15 AFI84716.1 - 3.6e-12 46.4 1.4 4.2e-12 46.2 1.4 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain TonB_dep_Rec PF00593.24 AFI84717.1 - 1.2e-49 170.4 34.8 1.2e-49 170.4 34.8 1.4 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AFI84717.1 - 3.8e-20 72.5 1.7 7e-20 71.6 0.5 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain EI24 PF07264.11 AFI84718.1 - 2.7e-37 128.7 19.8 3.1e-37 128.5 19.8 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FGGY_N PF00370.21 AFI84719.1 - 2.2e-13 50.3 0.0 3.3e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 AFI84719.1 - 7.5e-10 38.9 0.0 2.5e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain QueF PF14489.6 AFI84720.1 - 1.6e-31 108.3 0.0 2e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 QueF-like protein Fe-S_biosyn PF01521.20 AFI84720.1 - 0.0043 17.2 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis QueF_N PF14819.6 AFI84720.1 - 0.033 14.5 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term GTP_cyclohydroI PF01227.22 AFI84720.1 - 0.057 12.8 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I ZipA_C PF04354.13 AFI84721.1 - 4.3e-40 136.5 0.1 6.3e-40 136.0 0.1 1.2 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain SHR3_chaperone PF08229.11 AFI84721.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 DNA_ligase_aden PF01653.18 AFI84722.1 - 3.8e-133 443.5 0.0 6.1e-133 442.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AFI84722.1 - 3e-36 123.1 5.2 3e-36 123.1 5.2 2.3 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 AFI84722.1 - 3e-24 84.9 0.3 4.7e-22 77.9 0.1 3.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.26 AFI84722.1 - 1.2e-12 48.0 0.0 3.8e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 AFI84722.1 - 1.8e-12 47.6 0.0 6e-07 30.0 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_ligase_ZBD PF03119.16 AFI84722.1 - 4.5e-10 39.4 5.0 1.1e-09 38.1 5.0 1.7 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain PTCB-BRCT PF12738.7 AFI84722.1 - 1.7e-05 24.7 0.0 6.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain HHH PF00633.23 AFI84722.1 - 0.0005 19.8 0.0 0.013 15.4 0.0 3.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif Zn-ribbon_8 PF09723.10 AFI84722.1 - 0.19 11.9 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-NADH-PPase PF09297.11 AFI84722.1 - 0.25 11.0 3.8 0.5 10.1 3.8 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Glycos_transf_3 PF00591.21 AFI84723.1 - 2e-13 50.5 0.1 4.5e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AFI84723.1 - 9.6e-13 47.8 0.9 2.9e-12 46.3 0.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain UPF0047 PF01894.17 AFI84724.1 - 1.2e-34 118.9 0.0 1.4e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PaO PF08417.12 AFI84724.1 - 0.058 13.5 0.1 0.79 9.9 0.0 2.1 1 1 1 2 2 2 0 Pheophorbide a oxygenase DUF615 PF04751.14 AFI84725.1 - 1.1e-45 155.4 7.9 1.2e-45 155.2 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF615) DUF43 PF01861.16 AFI84725.1 - 0.016 14.4 0.5 0.029 13.6 0.0 1.6 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain HAUS-augmin3 PF14932.6 AFI84725.1 - 0.053 13.1 9.3 0.028 14.0 7.1 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 AFI84725.1 - 0.092 13.4 7.0 0.096 13.3 3.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF3038 PF11237.8 AFI84725.1 - 0.29 11.2 6.7 0.11 12.5 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) NYD-SP28 PF14772.6 AFI84725.1 - 1.8 8.7 12.0 0.83 9.7 3.8 2.5 2 0 0 2 2 2 0 Sperm tail HATPase_c PF02518.26 AFI84726.1 - 6.6e-14 52.4 0.0 1.6e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI84726.1 - 2.6e-07 30.5 0.0 8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AFI84726.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA PF00512.25 AFI84726.1 - 0.0021 18.1 3.1 0.038 14.0 0.1 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AFI84726.1 - 0.0063 16.9 0.3 0.015 15.7 0.0 1.8 2 0 0 2 2 2 1 HAMP domain Brix PF04427.18 AFI84726.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.4 1 1 0 1 1 1 0 Brix domain HATPase_c_3 PF13589.6 AFI84726.1 - 0.091 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAPES3 PF17154.4 AFI84726.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain UPF0242 PF06785.11 AFI84726.1 - 1.6 8.8 7.0 0.36 10.9 3.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Response_reg PF00072.24 AFI84727.1 - 1.5e-25 89.5 0.0 2.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84727.1 - 4.9e-23 81.0 0.3 1.1e-22 79.8 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal PepSY PF03413.19 AFI84728.1 - 0.028 15.0 0.0 0.036 14.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF3418 PF11898.8 AFI84730.1 - 4.8e-210 699.2 5.1 8.3e-210 698.4 5.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) HA2 PF04408.23 AFI84730.1 - 2e-17 63.4 0.0 4.9e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 AFI84730.1 - 1e-16 61.1 0.0 2.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 AFI84730.1 - 3.7e-10 40.1 0.0 1.2e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AFI84730.1 - 8.7e-07 28.9 0.1 2.2e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AFI84730.1 - 2e-06 28.2 0.0 4.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI84730.1 - 0.00027 20.1 0.0 0.00057 19.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AFI84730.1 - 0.00032 21.0 0.3 0.0018 18.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AFI84730.1 - 0.00037 19.8 0.0 0.00082 18.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AFI84730.1 - 0.0034 17.3 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 AFI84730.1 - 0.011 15.3 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AFI84730.1 - 0.013 15.4 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AFI84730.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AFI84730.1 - 0.033 14.2 0.4 0.91 9.5 0.3 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 AFI84730.1 - 0.042 13.9 0.4 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 AFI84730.1 - 0.054 14.0 0.6 0.42 11.1 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Microtub_bd PF16796.5 AFI84730.1 - 0.079 12.9 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Microtubule binding PhoH PF02562.16 AFI84730.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 AFI84730.1 - 0.14 12.6 0.1 0.14 12.6 0.1 3.2 2 1 1 3 3 2 0 AAA domain DUF481 PF04338.12 AFI84731.1 - 7.6e-26 91.4 8.8 9.8e-26 91.1 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF481 Pentapeptide PF00805.22 AFI84732.1 - 7e-25 86.3 1.2 4.7e-09 35.7 0.1 3.3 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AFI84732.1 - 3.3e-10 40.0 0.0 2.2e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AFI84732.1 - 1.4e-08 34.7 0.0 0.0012 18.9 0.0 3.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Nitroreductase PF00881.24 AFI84733.1 - 5e-17 62.5 0.0 8.9e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AFI84733.1 - 0.0032 17.1 0.0 0.69 9.4 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase CRS1_YhbY PF01985.21 AFI84734.1 - 7.8e-25 86.9 0.1 8.7e-25 86.7 0.1 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain FleQ PF06490.11 AFI84734.1 - 0.04 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ RuBisCO_small PF00101.20 AFI84734.1 - 0.089 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain HGD-D PF06050.13 AFI84734.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component UPF0020 PF01170.18 AFI84735.1 - 3.1e-44 151.0 0.0 7.7e-43 146.5 0.0 2.2 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.9 AFI84735.1 - 6e-28 97.8 0.1 9.7e-28 97.1 0.1 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AFI84735.1 - 7.7e-18 64.8 0.0 3.1e-11 43.2 0.0 3.4 3 0 0 3 3 3 2 Conserved hypothetical protein 95 THUMP PF02926.17 AFI84735.1 - 2.1e-13 50.6 0.0 4.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Methyltransf_31 PF13847.6 AFI84735.1 - 2.3e-08 34.0 0.0 6e-05 22.9 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 AFI84735.1 - 4.8e-08 32.7 0.0 0.013 15.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 AFI84735.1 - 1.3e-07 32.3 0.1 0.00054 20.6 0.0 3.7 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_15 PF09445.10 AFI84735.1 - 1.3e-06 28.1 0.0 0.019 14.5 0.0 2.8 3 0 0 3 3 3 2 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 AFI84735.1 - 0.00067 19.1 0.3 0.42 10.0 0.1 3.4 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 AFI84735.1 - 0.0016 19.0 0.0 0.019 15.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 AFI84735.1 - 0.0093 15.3 0.0 0.17 11.1 0.0 2.8 2 1 0 2 2 2 1 N-6 DNA Methylase AviRa PF11599.8 AFI84735.1 - 0.013 15.0 0.0 4.4 6.7 0.0 3.5 3 0 0 3 3 3 0 RRNA methyltransferase AviRa Methyltransf_23 PF13489.6 AFI84735.1 - 0.032 14.1 0.0 0.23 11.3 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.6 AFI84735.1 - 0.038 15.0 0.0 12 7.0 0.0 3.1 2 0 0 2 2 2 0 Methyltransferase domain AAA_31 PF13614.6 AFI84736.1 - 5.2e-37 127.5 0.0 6.8e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AFI84736.1 - 1.5e-10 41.2 0.0 2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AFI84736.1 - 4e-08 33.0 0.0 6.9e-08 32.3 0.0 1.4 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AFI84736.1 - 1.7e-07 30.8 0.0 8.8e-06 25.2 0.0 2.4 2 1 0 2 2 2 1 ATPase MipZ ParA PF10609.9 AFI84736.1 - 1.7e-06 27.7 0.0 9.9e-06 25.2 0.0 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AFI84736.1 - 2.9e-05 23.4 0.0 9.9e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AFI84736.1 - 0.0057 16.0 0.1 0.02 14.2 0.0 1.9 1 1 0 2 2 2 1 VirC1 protein Fer4_NifH PF00142.18 AFI84736.1 - 0.041 13.3 0.0 0.29 10.6 0.0 2.3 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PP_kinase_C_1 PF17941.1 AFI84737.1 - 2.5e-72 241.9 0.4 6.1e-72 240.6 0.1 1.8 1 1 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 AFI84737.1 - 1.6e-66 223.0 0.0 4.6e-66 221.5 0.0 1.8 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 AFI84737.1 - 2e-64 216.9 0.0 3.3e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 AFI84737.1 - 7.5e-35 119.5 0.1 2.5e-34 117.8 0.1 1.9 2 0 0 2 2 2 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 AFI84737.1 - 4.2e-11 42.9 0.1 1.4e-06 28.3 0.1 2.8 2 1 0 2 2 2 2 PLD-like domain CxxCxxCC PF03692.15 AFI84739.1 - 3.6e-07 30.8 9.5 7.2e-07 29.8 9.5 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain HTH_IclR PF09339.10 AFI84740.1 - 0.0061 16.3 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain DUF2043 PF09740.9 AFI84740.1 - 0.096 13.4 0.1 0.21 12.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) DprA_WH PF17782.1 AFI84740.1 - 0.15 12.2 0.2 0.56 10.4 0.2 2.0 1 1 0 1 1 1 0 DprA winged helix domain Peptidase_M18 PF02127.15 AFI84741.1 - 5e-141 470.4 0.0 5.8e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 AFI84741.1 - 1.2e-08 34.4 0.1 0.00028 20.0 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase DUF445 PF04286.12 AFI84743.1 - 2.6e-14 53.8 0.0 2.8e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF445) ThrE_2 PF12821.7 AFI84743.1 - 0.034 14.3 0.4 0.19 11.9 0.2 2.2 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE Methyltransf_23 PF13489.6 AFI84744.1 - 1.2e-19 70.8 0.0 1.6e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84744.1 - 8e-06 26.5 0.0 8.4e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI84744.1 - 7.5e-05 23.3 0.0 0.00035 21.2 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI84744.1 - 0.0013 19.4 0.2 0.093 13.4 0.0 3.1 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI84744.1 - 0.018 14.9 0.0 0.077 12.8 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain UPF0029 PF01205.19 AFI84745.1 - 1.1e-27 96.4 0.0 1.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 AFI84745.1 - 6.7e-09 35.5 0.1 1.2e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) RapA_C PF12137.8 AFI84746.1 - 1.2e-126 422.6 13.2 2.1e-126 421.8 13.2 1.4 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Tudor_1_RapA PF18339.1 AFI84746.1 - 1.8e-25 88.6 0.1 4.5e-25 87.3 0.1 1.7 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain 1 SNF2_N PF00176.23 AFI84746.1 - 9.4e-19 67.3 0.1 2.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tudor_RapA PF18337.1 AFI84746.1 - 7.2e-17 61.3 0.1 3.4e-16 59.2 0.0 2.3 2 0 0 2 2 1 1 RapA N-terminal Tudor like domain Helicase_C PF00271.31 AFI84746.1 - 3.5e-14 53.1 0.0 1.4e-13 51.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AFI84746.1 - 3.4e-13 49.9 4.9 6.2e-13 49.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AFI84746.1 - 4.8e-08 33.0 0.2 4.8e-08 33.0 0.2 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 AFI84746.1 - 0.0051 15.7 0.3 0.016 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Helicase_RecD PF05127.14 AFI84746.1 - 0.0052 16.7 3.2 0.022 14.6 0.0 2.8 2 0 0 2 2 2 1 Helicase TTRAP PF14203.6 AFI84746.1 - 0.012 15.6 2.4 0.014 15.4 0.7 1.9 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Flavi_DEAD PF07652.14 AFI84746.1 - 0.031 14.3 0.1 0.15 12.0 0.1 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF1323 PF07037.11 AFI84746.1 - 0.19 12.1 1.4 0.68 10.3 1.0 2.3 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) AAA_22 PF13401.6 AFI84746.1 - 7.6 6.8 7.5 1.3 9.3 0.1 3.4 3 2 1 4 4 4 0 AAA domain Rnk_N PF14760.6 AFI84746.1 - 9.1 6.9 6.8 11 6.6 0.1 4.1 4 0 0 4 4 4 0 Rnk N-terminus HlyD_3 PF13437.6 AFI84747.1 - 7.4e-16 58.8 1.1 4.5e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI84747.1 - 4.8e-14 51.9 0.9 2.7e-10 39.9 0.6 4.6 4 0 0 4 4 4 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AFI84747.1 - 7.7e-09 35.1 9.5 1.2e-07 31.2 9.5 2.1 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AFI84747.1 - 7.1e-06 25.8 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme PYNP_C PF07831.13 AFI84747.1 - 0.043 13.5 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain ACR_tran PF00873.19 AFI84748.1 - 1.6e-159 532.6 4.3 2e-159 532.3 4.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI84748.1 - 1.5e-09 37.2 4.0 1.5e-09 37.2 4.0 3.0 4 0 0 4 4 4 1 MMPL family Mis14 PF08641.12 AFI84748.1 - 0.79 10.0 0.0 0.79 10.0 0.0 2.2 4 0 0 4 4 4 0 Kinetochore protein Mis14 like Colicin PF01024.19 AFI84748.1 - 1.7 8.5 8.8 0.24 11.3 2.7 2.6 2 0 0 2 2 2 0 Colicin pore forming domain OEP PF02321.18 AFI84749.1 - 1e-19 71.1 29.8 6.5e-13 48.9 18.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein RTT107_BRCT_5 PF16770.5 AFI84749.1 - 0.03 14.2 1.4 3.1 7.7 0.1 2.4 1 1 1 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DOR PF14839.6 AFI84749.1 - 2.6 7.9 8.5 0.16 11.9 2.5 1.9 2 0 0 2 2 2 0 DOR family Peptidase_C93 PF06035.11 AFI84750.1 - 3.9e-16 59.3 0.1 8.6e-16 58.1 0.1 1.5 1 1 1 2 2 2 1 Bacterial transglutaminase-like cysteine proteinase BTLCP LapD_MoxY_N PF16448.5 AFI84751.1 - 2.4e-40 137.2 0.0 6.3e-40 135.9 0.0 1.8 1 0 0 1 1 1 1 LapD/MoxY periplasmic domain EAL PF00563.20 AFI84751.1 - 5.3e-27 94.9 0.3 1.3e-26 93.6 0.3 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI84751.1 - 5e-14 52.4 0.3 9.7e-14 51.4 0.3 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 AFI84751.1 - 4.5e-05 23.8 0.1 0.0005 20.4 0.0 2.6 2 0 0 2 2 2 1 HAMP domain DUF1664 PF07889.12 AFI84751.1 - 0.023 14.7 0.4 0.24 11.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 AFI84751.1 - 0.18 12.1 5.8 1.1 9.5 2.7 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mem_trans PF03547.18 AFI84752.1 - 1.9e-22 79.2 29.0 4.8e-15 54.8 14.5 2.0 1 1 1 2 2 2 2 Membrane transport protein MoCF_biosynth PF00994.24 AFI84753.1 - 2e-25 89.1 0.0 3.2e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Bac_globin PF01152.21 AFI84754.1 - 7.3e-37 126.2 0.0 8.2e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Fae PF08714.11 AFI84755.1 - 4e-61 205.6 0.3 4.5e-61 205.4 0.3 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Helicase_C_2 PF13307.6 AFI84758.1 - 1.2e-36 126.5 0.0 2e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 AFI84758.1 - 3.1e-06 27.3 0.1 5.7e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AFI84758.1 - 3.3e-06 27.0 0.6 0.0016 18.2 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase DEAD_2 PF06733.15 AFI84758.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Glyco_tran_10_N PF17039.5 AFI84758.1 - 0.0082 16.6 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal PhoH PF02562.16 AFI84758.1 - 0.095 12.1 0.7 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Sulfatase PF00884.23 AFI84758.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Sulfatase Methyltransf_7 PF03492.15 AFI84758.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DUF2237 PF09996.9 AFI84759.1 - 3.4e-54 181.7 0.0 3.8e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Pterin_4a PF01329.19 AFI84760.1 - 1.4e-24 86.1 0.2 1.7e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Phage_integrase PF00589.22 AFI84762.1 - 2.1e-29 102.5 0.0 3.9e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AFI84762.1 - 0.00093 19.4 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain TniQ PF06527.11 AFI84763.1 - 0.0041 17.8 0.3 0.0041 17.8 0.3 1.8 2 0 0 2 2 2 1 TniQ zinc_ribbon_15 PF17032.5 AFI84763.1 - 0.15 12.8 5.3 0.4 11.4 5.3 1.8 1 0 0 1 1 1 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 AFI84763.1 - 0.43 10.1 6.4 2.1 7.9 0.2 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 AFI84763.1 - 2.7 8.2 7.5 17 5.7 0.4 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AFI84763.1 - 5.4 7.1 7.5 60 3.7 3.4 2.7 1 1 2 3 3 3 0 Transposase zinc-ribbon domain AAA_22 PF13401.6 AFI84764.1 - 2.6e-10 40.7 0.1 5.9e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AFI84764.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 AFI84764.1 - 0.0018 18.7 0.0 0.077 13.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 AFI84764.1 - 0.0097 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.6 AFI84764.1 - 0.026 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AFI84764.1 - 0.033 14.5 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AFI84764.1 - 0.039 13.8 0.1 0.096 12.6 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 AFI84764.1 - 0.16 12.0 0.4 2.1 8.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain rve PF00665.26 AFI84765.1 - 2.9e-11 43.6 0.0 9.7e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 AFI84765.1 - 1.5e-05 24.7 0.4 0.035 13.9 0.0 2.8 2 0 0 2 2 2 2 Integrase core domain Sigma70_r4 PF04545.16 AFI84765.1 - 0.019 14.5 0.4 0.046 13.2 0.4 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Mu-transpos_C PF09299.11 AFI84765.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Mu transposase, C-terminal Tn7_Tnp_TnsA_N PF08722.11 AFI84766.1 - 0.0047 17.1 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 TnsA endonuclease N terminal PCI PF01399.27 AFI84766.1 - 0.052 14.1 0.1 0.11 13.1 0.1 1.5 1 1 0 1 1 1 0 PCI domain Kdo PF06293.14 AFI84768.1 - 9.3e-30 103.5 0.4 1.1e-29 103.2 0.4 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 AFI84768.1 - 0.00033 20.1 0.4 0.00049 19.5 0.3 1.3 1 1 0 1 1 1 1 Protein kinase domain Methyltransf_11 PF08241.12 AFI84769.1 - 1.6e-14 54.3 0.0 2.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI84769.1 - 2.3e-14 53.9 0.0 3.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI84769.1 - 6.1e-11 42.4 0.0 7.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI84769.1 - 5.4e-10 39.3 0.0 8.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI84769.1 - 6e-10 39.8 0.0 5.3e-09 36.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AFI84769.1 - 4.6e-09 35.9 0.0 1.8e-08 34.0 0.0 1.8 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 AFI84769.1 - 0.0052 16.9 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Sulfatase PF00884.23 AFI84770.1 - 1e-43 149.9 0.0 1.3e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AFI84770.1 - 0.0029 17.2 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 AFI84770.1 - 0.011 15.1 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.17 AFI84770.1 - 0.047 12.3 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) LYTB PF02401.18 AFI84770.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 LytB protein DAGK_prokar PF01219.19 AFI84771.1 - 4.1e-20 71.5 2.4 4.4e-20 71.4 2.4 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase PAP2 PF01569.21 AFI84772.1 - 9e-09 35.2 4.7 9e-09 35.2 4.7 2.0 3 0 0 3 3 3 1 PAP2 superfamily Response_reg PF00072.24 AFI84773.1 - 1.3e-19 70.4 0.1 2e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84773.1 - 1.1e-17 63.9 0.2 3.8e-17 62.1 0.1 2.0 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AFI84773.1 - 0.0034 17.7 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ HATPase_c PF02518.26 AFI84774.1 - 1.2e-14 54.8 0.3 2.8e-14 53.6 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84774.1 - 7.6e-13 48.3 2.9 9.1e-13 48.1 1.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AFI84774.1 - 7.5e-10 38.6 1.1 2.1e-09 37.2 1.1 1.8 1 0 0 1 1 1 1 GHKL domain 2CSK_N PF08521.10 AFI84774.1 - 0.0013 18.9 0.0 0.0036 17.4 0.0 1.8 1 1 0 1 1 1 1 Two-component sensor kinase N-terminal 4HB_MCP_1 PF12729.7 AFI84774.1 - 0.0086 15.6 0.5 0.0086 15.6 0.5 2.3 3 0 0 3 3 3 1 Four helix bundle sensory module for signal transduction Trp_repressor PF01371.19 AFI84774.1 - 0.053 13.6 0.5 0.13 12.4 0.2 1.9 2 1 0 2 2 2 0 Trp repressor protein TruB-C_2 PF09157.11 AFI84774.1 - 0.16 12.1 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal Sulfatase PF00884.23 AFI84775.1 - 1e-44 153.2 0.0 1.5e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 AFI84775.1 - 2.2e-41 141.2 6.2 4.6e-41 140.2 6.2 1.5 1 0 0 1 1 1 1 Phosphoethanolamine transferase EptA/EptB rve_2 PF13333.6 AFI84777.1 - 0.00023 21.3 0.3 0.00026 21.1 0.3 1.1 1 0 0 1 1 1 1 Integrase core domain DUF676 PF05057.14 AFI84778.1 - 5.1e-09 36.0 0.0 1.5e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 AFI84778.1 - 2.9e-07 30.5 0.0 2.5e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 AFI84778.1 - 0.004 17.8 0.0 0.008 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 AFI84778.1 - 0.012 14.8 0.0 0.028 13.6 0.0 1.6 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2384 PF09722.10 AFI84780.1 - 5.3e-16 58.4 0.0 8.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Alpha_Helical PF18489.1 AFI84780.1 - 0.042 14.0 0.0 0.044 14.0 0.0 1.0 1 0 0 1 1 1 0 Alpha helical domain ResIII PF04851.15 AFI84782.1 - 1.7e-34 119.3 0.0 6.2e-34 117.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AFI84782.1 - 7.3e-17 61.8 1.4 9.4e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase EcoEI_R_C PF08463.10 AFI84782.1 - 1.9e-16 60.7 0.8 1.5e-15 57.7 0.0 2.6 2 0 0 2 2 2 1 EcoEI R protein C-terminal DUF4145 PF13643.6 AFI84782.1 - 2.1e-12 47.0 0.0 1e-11 44.8 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) DEAD PF00270.29 AFI84782.1 - 4.7e-09 36.3 0.8 1.6e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI84782.1 - 1.5e-06 28.5 0.0 6.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSDR_N PF04313.14 AFI84782.1 - 1.6e-06 28.2 0.8 0.00044 20.2 0.0 3.0 2 1 1 3 3 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) AAA_34 PF13872.6 AFI84782.1 - 3.2e-05 23.0 0.1 6.9e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF2075 PF09848.9 AFI84782.1 - 0.0042 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) HSDR_N_2 PF13588.6 AFI84782.1 - 0.0045 17.0 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) AAA_11 PF13086.6 AFI84782.1 - 0.074 12.8 3.0 33 4.1 0.0 3.7 3 1 1 4 4 4 0 AAA domain CtsR_C PF17727.1 AFI84782.1 - 0.09 12.9 0.1 13 5.9 0.0 3.4 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain Methylase_S PF01420.19 AFI84783.1 - 3.7e-11 43.5 0.2 8.5e-11 42.4 0.2 1.7 1 1 1 2 2 2 1 Type I restriction modification DNA specificity domain Methylase_S PF01420.19 AFI84784.1 - 0.096 12.9 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain N6_Mtase PF02384.16 AFI84785.1 - 1.6e-66 224.7 0.0 2.1e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AFI84785.1 - 9.4e-16 58.7 0.0 4.2e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 HsdM N-terminal domain UPF0020 PF01170.18 AFI84785.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 AFI84785.1 - 0.00038 20.3 0.0 0.0016 18.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Eco57I PF07669.11 AFI84785.1 - 0.00091 19.7 0.0 0.0027 18.2 0.0 1.9 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 AFI84785.1 - 0.058 12.9 0.0 0.49 9.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Molybdopterin PF00384.22 AFI84786.1 - 1.5e-62 211.9 0.0 2.2e-61 208.2 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI84786.1 - 2.9e-18 65.9 0.0 6.2e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AFI84786.1 - 2.6e-09 36.9 0.5 5.4e-09 35.9 0.5 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain PUA_3 PF17785.1 AFI84786.1 - 0.00098 18.9 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 PUA-like domain TruB-C_2 PF09157.11 AFI84786.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal Fer4 PF00037.27 AFI84787.1 - 8.8e-10 38.0 14.8 1.2e-07 31.2 5.5 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AFI84787.1 - 2.1e-09 37.3 22.4 3.7e-06 26.9 13.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AFI84787.1 - 2.5e-08 34.7 6.2 4.5e-05 24.3 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AFI84787.1 - 3.9e-08 33.0 14.3 5.9e-05 23.0 5.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AFI84787.1 - 3.8e-07 29.8 14.1 0.00018 21.4 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AFI84787.1 - 1.6e-06 28.6 26.9 3.8e-05 24.2 14.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI84787.1 - 4.2e-06 26.8 10.6 7.1e-06 26.1 10.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI84787.1 - 3.6e-05 23.9 13.9 0.012 16.1 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AFI84787.1 - 4e-05 24.0 4.5 0.0049 17.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AFI84787.1 - 6.5e-05 23.4 5.4 0.0039 17.7 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain DUF3470 PF11953.8 AFI84787.1 - 9.8e-05 22.2 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4_21 PF14697.6 AFI84787.1 - 0.00012 22.2 11.5 0.002 18.2 1.9 2.1 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.6 AFI84787.1 - 0.022 14.9 8.4 0.087 12.9 8.3 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AFI84787.1 - 0.038 14.9 17.5 0.27 12.3 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AFI84787.1 - 0.33 11.2 7.9 0.69 10.1 0.6 1.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 AFI84788.1 - 3.7e-08 32.9 0.0 4.5e-07 29.4 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AFI84788.1 - 0.00089 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 AFI84788.1 - 0.0017 18.9 0.2 0.78 10.3 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AFI84788.1 - 0.0022 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 AFI84788.1 - 0.0076 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AFI84788.1 - 0.059 12.6 0.5 1.3 8.2 0.1 2.5 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AFI84788.1 - 0.077 11.7 0.0 0.33 9.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein PQQ PF01011.21 AFI84790.1 - 6.5e-25 85.8 15.1 1.1e-06 28.2 0.0 7.5 7 0 0 7 7 7 5 PQQ enzyme repeat PQQ_2 PF13360.6 AFI84790.1 - 1.3e-16 60.9 0.7 1.1e-08 35.0 0.0 3.0 4 1 0 4 4 4 2 PQQ-like domain PQQ_3 PF13570.6 AFI84790.1 - 2.3e-10 40.6 7.3 0.0069 16.9 0.2 6.0 5 0 0 5 5 5 3 PQQ-like domain NAD_binding_1 PF00175.21 AFI84791.1 - 4.3e-17 62.7 0.1 1.1e-16 61.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 AFI84791.1 - 3.7e-12 46.8 1.6 3.8e-12 46.7 0.2 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 AFI84791.1 - 2.9e-09 37.2 0.0 5.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 AFI84791.1 - 6.5e-05 22.9 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 AFI84791.1 - 0.0048 17.0 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Cupredoxin_1 PF13473.6 AFI84795.1 - 2.3e-24 85.5 0.0 2.5e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Cupredoxin-like domain HATPase_c PF02518.26 AFI84796.1 - 1.2e-20 74.1 0.0 3.2e-20 72.7 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI84796.1 - 3.8e-12 46.0 1.6 3.1e-11 43.2 0.3 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain 2CSK_N PF08521.10 AFI84796.1 - 9.4e-12 45.2 0.1 3e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 Two-component sensor kinase N-terminal HATPase_c_2 PF13581.6 AFI84796.1 - 3.6e-05 23.7 0.1 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AFI84796.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI84796.1 - 0.024 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 GHKL domain HAMP PF00672.25 AFI84796.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 HAMP domain Img2 PF05046.14 AFI84796.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Response_reg PF00072.24 AFI84797.1 - 1e-26 93.3 0.1 1.5e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI84797.1 - 6.5e-20 71.0 0.1 1.3e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal OKR_DC_1_N PF03709.15 AFI84797.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PilO PF04350.13 AFI84797.1 - 0.16 12.1 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO TPR_17 PF13431.6 AFI84798.1 - 0.00037 20.7 0.3 0.68 10.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AFI84798.1 - 0.0014 19.1 3.4 0.0065 16.9 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AFI84798.1 - 0.0016 19.1 0.1 0.012 16.2 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI84798.1 - 0.0091 16.2 0.6 0.024 14.8 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 AFI84798.1 - 0.018 14.7 4.2 10 5.9 0.4 4.1 4 1 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 AFI84798.1 - 0.11 12.8 16.4 2.3 8.7 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 AFI84798.1 - 0.11 12.3 7.4 8.6 6.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 AFI84798.1 - 0.16 12.2 10.3 4.5 7.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Vta1_C PF18097.1 AFI84798.1 - 0.38 10.5 4.4 0.4 10.4 0.0 2.9 3 0 0 3 3 3 0 Vta1 C-terminal domain adh_short PF00106.25 AFI84799.1 - 1.7e-43 148.3 0.1 2.1e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AFI84799.1 - 4.3e-24 85.4 0.1 5.6e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AFI84799.1 - 1.8e-10 41.0 0.4 4.3e-10 39.8 0.2 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 AFI84799.1 - 1.6e-05 24.5 0.1 3.1e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AFI84799.1 - 7.7e-05 22.2 0.0 0.00018 21.0 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 AFI84799.1 - 0.0034 16.5 0.2 0.0055 15.8 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AFI84799.1 - 0.0068 16.3 0.2 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AFI84799.1 - 0.03 13.4 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AFI84799.1 - 0.076 12.4 0.5 1.2 8.4 0.4 2.1 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AFI84799.1 - 0.48 9.5 2.6 10 5.2 2.6 2.2 1 1 0 1 1 1 0 Male sterility protein Haem_oxygenas_2 PF14518.6 AFI84800.1 - 3.3e-26 92.2 1.4 3.8e-26 91.9 1.4 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme TENA_THI-4 PF03070.16 AFI84800.1 - 0.0011 18.8 0.1 0.0015 18.4 0.1 1.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family AMP-binding PF00501.28 AFI84801.1 - 2e-53 181.6 0.0 3.9e-53 180.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme T_hemolysin PF12261.8 AFI84802.1 - 3.3e-58 196.3 0.1 4.2e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 Thermostable hemolysin RHH_1 PF01402.21 AFI84803.1 - 0.0079 16.1 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Sulfate_transp PF00916.20 AFI84804.1 - 3.1e-81 273.0 23.2 4.1e-81 272.7 23.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 AFI84804.1 - 3.7e-12 45.9 0.0 6.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AFI84804.1 - 0.0065 16.8 0.1 0.034 14.5 0.1 2.3 3 0 0 3 3 3 1 STAS domain Sulfatase PF00884.23 AFI84805.1 - 1.1e-39 136.7 0.1 1.5e-39 136.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Peptidase_M56 PF05569.11 AFI84805.1 - 2.3 7.3 5.5 1.6 7.9 1.2 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 DAGK_prokar PF01219.19 AFI84806.1 - 2.8e-29 100.9 2.6 3.1e-29 100.8 2.6 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase DUF202 PF02656.15 AFI84806.1 - 0.52 10.8 4.3 1.4 9.4 4.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) GST_N_2 PF13409.6 AFI84807.1 - 1.1e-23 83.3 0.0 7.7e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AFI84807.1 - 4.9e-13 48.9 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AFI84807.1 - 4.9e-07 29.9 0.1 8.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AFI84807.1 - 3.3e-06 27.2 0.1 6.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AFI84807.1 - 1.7e-05 25.1 0.0 0.00037 20.8 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 AFI84807.1 - 0.005 16.6 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IDO PF01231.18 AFI84808.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase SecD_SecF PF02355.16 AFI84809.1 - 2.9e-72 242.0 19.8 6.6e-58 195.2 5.2 2.4 2 0 0 2 2 2 2 Protein export membrane protein Sec_GG PF07549.14 AFI84809.1 - 2.4e-13 49.1 2.0 5.1e-06 25.8 0.1 2.7 2 0 0 2 2 2 2 SecD/SecF GG Motif MMPL PF03176.15 AFI84809.1 - 8.9e-09 34.7 13.3 8.9e-09 34.7 13.3 3.0 2 1 0 2 2 2 1 MMPL family ACR_tran PF00873.19 AFI84809.1 - 6.8e-08 30.7 24.6 0.00017 19.4 9.0 2.4 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family UPF0180 PF03698.13 AFI84809.1 - 0.00063 19.9 3.2 0.51 10.5 0.1 4.5 4 1 0 4 4 4 1 Uncharacterised protein family (UPF0180) Phage_holin_3_6 PF07332.11 AFI84809.1 - 0.0045 17.0 27.1 0.0078 16.2 0.9 4.4 4 0 0 4 4 4 3 Putative Actinobacterial Holin-X, holin superfamily III GGDEF_2 PF17853.1 AFI84809.1 - 0.016 15.5 0.0 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 GGDEF-like domain AP_endonuc_2 PF01261.24 AFI84809.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Sterol-sensing PF12349.8 AFI84809.1 - 0.077 12.8 16.0 0.51 10.2 2.9 2.7 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation DUF5333 PF17267.2 AFI84809.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5333) SecD-TM1 PF13721.6 AFI84809.1 - 0.12 12.9 3.1 39 4.8 0.0 4.0 4 0 0 4 4 4 0 SecD export protein N-terminal TM region Na_Ca_ex PF01699.24 AFI84810.1 - 8.9e-60 201.0 49.6 1.3e-32 112.9 18.4 2.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Saf_2TM PF18303.1 AFI84810.1 - 0.12 12.0 13.3 0.037 13.6 1.3 3.1 1 1 2 3 3 3 0 SAVED-fused 2TM effector domain Peptidase_M48 PF01435.18 AFI84811.1 - 1.1e-30 106.9 0.3 1.1e-30 106.9 0.3 1.4 2 0 0 2 2 2 1 Peptidase family M48 DUF3357 PF11837.8 AFI84811.1 - 0.017 15.6 1.5 0.92 10.0 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Peptidase_M56 PF05569.11 AFI84811.1 - 0.086 12.0 0.1 0.086 12.0 0.1 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 7tm_3 PF00003.22 AFI84811.1 - 0.18 11.5 3.4 0.078 12.7 0.7 1.7 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Peptidase_A24 PF01478.18 AFI84811.1 - 0.32 11.4 8.1 0.16 12.4 3.7 2.3 2 0 0 2 2 2 0 Type IV leader peptidase family Sigma_reg_N PF13800.6 AFI84811.1 - 0.4 11.0 2.3 0.49 10.7 0.1 2.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal FtsX PF02687.21 AFI84811.1 - 0.68 10.5 12.5 0.74 10.3 4.5 2.7 2 0 0 2 2 2 0 FtsX-like permease family LemA PF04011.12 AFI84812.1 - 1.2e-53 181.0 0.1 1.5e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 LemA family Pro-rich_19 PF15455.6 AFI84812.1 - 0.069 12.3 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Proline-rich 19 ABC_tran PF00005.27 AFI84814.1 - 6.5e-55 185.4 0.1 5.1e-27 95.1 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AFI84814.1 - 5.9e-15 55.9 9.3 0.00036 20.4 0.0 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AFI84814.1 - 1e-13 51.1 12.4 7.9e-13 48.3 8.0 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AFI84814.1 - 2.4e-07 30.4 0.4 0.34 10.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AFI84814.1 - 9.4e-07 28.9 0.1 0.0063 16.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 AFI84814.1 - 6e-06 25.9 1.4 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 AFI84814.1 - 6.7e-05 23.2 0.2 0.15 12.3 0.1 3.0 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AFI84814.1 - 0.00012 22.0 0.1 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AFI84814.1 - 0.00026 21.6 13.5 0.0016 18.9 0.8 3.7 3 2 0 4 4 4 2 AAA domain AAA_33 PF13671.6 AFI84814.1 - 0.00027 21.1 0.7 1.1 9.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 AFI84814.1 - 0.00036 21.1 0.3 1.2 9.7 0.0 3.5 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 AFI84814.1 - 0.002 18.2 0.3 0.58 10.2 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_14 PF13173.6 AFI84814.1 - 0.0021 18.1 0.0 4.3 7.4 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 AFI84814.1 - 0.003 17.3 0.1 3.6 7.3 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 AFI84814.1 - 0.0049 17.3 0.1 3.6 8.0 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 AFI84814.1 - 0.0068 16.0 0.1 0.29 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 AFI84814.1 - 0.0084 15.1 0.2 1.6 7.6 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 AFI84814.1 - 0.011 16.0 0.6 6.6 7.0 0.0 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 AFI84814.1 - 0.013 14.7 0.8 0.66 9.1 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain Roc PF08477.13 AFI84814.1 - 0.016 15.4 0.5 2 8.7 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 AFI84814.1 - 0.023 14.3 0.2 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 AFI84814.1 - 0.027 14.2 1.6 2.6 7.7 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 AFI84814.1 - 0.048 14.0 5.9 2.9 8.3 0.0 3.5 2 1 1 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 AFI84814.1 - 0.052 12.2 4.3 2.5 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 AFI84814.1 - 0.053 13.8 0.3 14 5.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AFI84814.1 - 0.064 13.2 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AFI84814.1 - 0.069 13.1 0.7 14 5.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Arf PF00025.21 AFI84814.1 - 0.12 11.8 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Viral_helicase1 PF01443.18 AFI84814.1 - 0.14 11.8 0.0 0.92 9.2 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 AFI84814.1 - 0.24 10.9 0.8 24 4.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AFI84814.1 - 0.33 10.6 1.6 6.6 6.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AFI84814.1 - 0.65 9.9 2.8 20 5.0 0.1 3.2 3 1 0 3 3 3 0 NTPase DUF87 PF01935.17 AFI84814.1 - 8.3 6.4 7.0 12 5.9 0.0 3.2 4 0 0 4 4 3 0 Helicase HerA, central domain Transposase_20 PF02371.16 AFI84815.1 - 1.3e-18 67.1 0.1 3.8e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AFI84815.1 - 0.053 13.4 1.7 0.065 13.1 0.4 1.8 2 0 0 2 2 2 0 Transposase DUF4485 PF14846.6 AFI84815.1 - 0.095 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) NIR_SIR PF01077.22 AFI84816.1 - 3e-55 186.1 0.0 4e-47 159.7 0.1 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AFI84816.1 - 8.2e-31 105.7 0.5 1.3e-15 57.0 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 AFI84817.1 - 5.3e-33 114.2 0.0 1.2e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 AFI84817.1 - 1.2e-32 113.3 0.0 2.7e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 AFI84817.1 - 6.3e-19 68.6 0.0 6.2e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FMN_red PF03358.15 AFI84817.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 AFI84817.1 - 0.0049 17.1 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.7 AFI84817.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.11 AFI84817.1 - 0.073 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like EAL PF00563.20 AFI84818.1 - 5.8e-72 242.0 0.6 1.2e-71 241.1 0.6 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI84818.1 - 8.9e-19 67.8 0.2 1.9e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AFI84818.1 - 3.5e-12 46.5 0.2 1.3e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 AFI84818.1 - 1.5e-07 32.1 0.0 3.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AFI84818.1 - 0.00056 20.2 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AFI84818.1 - 0.00065 20.0 0.0 0.014 15.7 0.0 2.8 3 1 0 3 3 3 1 GAF domain DUF2478 PF10649.9 AFI84818.1 - 0.069 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) PAS_3 PF08447.12 AFI84819.1 - 3.6e-82 270.7 3.4 3.2e-20 72.2 0.0 5.6 5 0 0 5 5 5 5 PAS fold PAS_9 PF13426.7 AFI84819.1 - 3.9e-37 126.7 4.9 1.2e-13 51.2 0.0 5.7 6 0 0 6 6 6 5 PAS domain PAS PF00989.25 AFI84819.1 - 3.2e-31 107.6 2.7 2.1e-12 47.0 0.1 5.3 5 0 0 5 5 5 4 PAS fold PAS_4 PF08448.10 AFI84819.1 - 1e-21 77.3 0.2 2.3e-07 31.1 0.0 5.2 5 0 0 5 5 5 2 PAS fold HATPase_c PF02518.26 AFI84819.1 - 6.9e-19 68.4 0.0 1.7e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AFI84819.1 - 3e-17 62.8 0.0 1e-16 61.1 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AFI84819.1 - 4.5e-15 55.3 0.2 1.3e-08 34.7 0.0 5.4 5 0 0 5 5 5 2 PAS domain GAF_2 PF13185.6 AFI84819.1 - 2.1e-12 47.5 0.0 5e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 AFI84819.1 - 2.9e-09 36.8 0.0 1.3e-08 34.7 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 AFI84819.1 - 2.8e-08 33.9 1.2 0.014 15.5 0.1 3.7 3 0 0 3 3 3 3 PAS domain GAF PF01590.26 AFI84819.1 - 1.8e-05 25.4 0.0 6.7e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 GAF domain PAS_7 PF12860.7 AFI84819.1 - 0.0092 16.1 0.1 0.9 9.7 0.0 3.6 3 0 0 3 3 3 1 PAS fold KIX_2 PF16987.5 AFI84819.1 - 0.13 12.3 0.2 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 KIX domain HATPase_c_3 PF13589.6 AFI84819.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MCPsignal PF00015.21 AFI84820.1 - 1.5e-46 158.4 27.6 1.5e-46 158.4 27.6 3.4 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AFI84820.1 - 7.4e-11 42.3 2.8 7.5e-10 39.0 0.0 3.5 4 0 0 4 4 4 1 HAMP domain FUSC PF04632.12 AFI84820.1 - 0.39 9.2 10.2 0.63 8.5 10.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ETRAMP PF09716.10 AFI84820.1 - 2.8 8.1 9.1 6.2 7.0 0.0 3.4 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) GARP PF16731.5 AFI84820.1 - 5.5 6.6 33.8 0.14 11.8 15.6 3.0 1 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Lipase_GDSL_2 PF13472.6 AFI84821.1 - 1.1e-21 78.1 0.2 3.5e-20 73.1 0.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AFI84821.1 - 2.8e-11 43.8 0.1 2.4e-09 37.5 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 AFI84821.1 - 5.8e-07 29.8 0.0 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family DUF826 PF05696.11 AFI84821.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF826) OSK PF17182.4 AFI84821.1 - 0.039 13.2 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 OSK domain MGDG_synth PF06925.11 AFI84821.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase TatD_DNase PF01026.21 AFI84822.1 - 3.1e-78 262.7 0.1 3.5e-78 262.5 0.1 1.0 1 0 0 1 1 1 1 TatD related DNase PilZ PF07238.14 AFI84823.1 - 2.5e-06 27.7 0.0 2.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 PilZ domain DNA_pol3_delta2 PF13177.6 AFI84825.1 - 1.8e-49 167.7 0.8 5.2e-49 166.2 0.4 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 AFI84825.1 - 3.9e-05 24.1 1.0 9.5e-05 22.8 0.3 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Allexi_40kDa PF05549.11 AFI84825.1 - 0.0024 17.5 1.7 0.005 16.4 1.7 1.5 1 0 0 1 1 1 1 Allexivirus 40kDa protein QueC PF06508.13 AFI84825.1 - 0.019 14.5 1.7 0.019 14.5 0.2 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC HJURP_C PF12347.8 AFI84825.1 - 0.068 13.2 0.6 0.17 12.0 0.6 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat AAA_16 PF13191.6 AFI84825.1 - 0.11 12.9 2.8 5.5 7.3 2.8 2.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 AFI84825.1 - 0.36 10.8 4.8 1 9.4 1.1 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 AFI84826.1 - 2.3e-52 177.4 0.2 2.6e-52 177.2 0.2 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AFI84826.1 - 3.3e-05 24.2 0.3 5.4e-05 23.5 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AFI84826.1 - 0.0051 17.2 0.3 0.023 15.1 0.3 2.0 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 AFI84826.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 AFI84826.1 - 0.023 15.0 0.5 0.069 13.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AFI84826.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AFI84826.1 - 0.3 11.6 1.6 0.59 10.6 1.6 1.9 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 AFI84826.1 - 1.5 9.3 5.4 33 4.9 5.4 2.1 1 1 0 1 1 1 0 AAA domain YceG PF02618.16 AFI84827.1 - 2.1e-84 283.3 0.0 2.4e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 YceG-like family Aminotran_4 PF01063.19 AFI84828.1 - 1.2e-50 172.5 0.0 1.4e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV ATPgrasp_ST PF14397.6 AFI84828.1 - 0.055 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ketoacyl-synt PF00109.26 AFI84829.1 - 2.2e-60 204.4 1.1 2.2e-60 204.4 1.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AFI84829.1 - 3.5e-39 133.5 3.0 7.6e-39 132.4 3.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AFI84829.1 - 0.00011 21.6 1.1 0.00011 21.6 1.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AFI84829.1 - 0.008 16.6 0.0 0.072 13.5 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 AFI84829.1 - 0.0088 15.9 3.6 0.2 11.5 0.0 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.25 AFI84830.1 - 4.8e-18 65.3 0.4 5.4e-18 65.1 0.4 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AFI84830.1 - 2.1e-05 24.7 0.6 2.2e-05 24.6 0.6 1.3 1 1 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 AFI84830.1 - 0.029 14.5 0.0 0.029 14.5 0.0 1.3 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF1493 PF07377.12 AFI84830.1 - 0.077 13.5 0.2 0.083 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HLH PF00010.26 AFI84830.1 - 0.08 12.9 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain adh_short_C2 PF13561.6 AFI84831.1 - 7.2e-66 222.1 4.4 8.2e-66 221.9 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AFI84831.1 - 1.1e-57 194.7 3.4 1.3e-57 194.5 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AFI84831.1 - 6.8e-18 65.2 0.9 9.2e-18 64.8 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AFI84831.1 - 0.00048 19.7 0.3 0.00082 18.9 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Tox-PL-2 PF15643.6 AFI84831.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 THF_DHG_CYH_C PF02882.19 AFI84831.1 - 0.032 13.6 0.3 0.081 12.2 0.3 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LDcluster4 PF18306.1 AFI84831.1 - 0.12 11.9 5.7 0.37 10.4 1.3 2.3 2 0 0 2 2 2 0 SLOG cluster4 family Acyl_transf_1 PF00698.21 AFI84832.1 - 7e-38 130.9 1.9 8.3e-38 130.7 1.9 1.0 1 0 0 1 1 1 1 Acyl transferase domain ACP_syn_III_C PF08541.10 AFI84833.1 - 9.8e-37 125.0 0.6 1.4e-35 121.3 0.1 2.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AFI84833.1 - 1.1e-36 124.5 1.3 1.4e-35 121.0 0.7 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AFI84833.1 - 9.2e-11 41.6 0.2 2.3e-10 40.3 0.0 1.6 1 1 1 2 2 2 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AFI84833.1 - 0.00061 19.2 0.0 0.0049 16.2 0.0 2.0 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ketoacyl-synt PF00109.26 AFI84833.1 - 0.0057 16.3 2.0 0.1 12.1 0.1 2.8 1 1 2 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 AFI84833.1 - 0.0067 15.2 0.3 0.082 11.6 0.0 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Chal_sti_synt_N PF00195.19 AFI84833.1 - 0.01 15.3 0.8 0.028 13.8 0.8 1.8 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Glyco_hydro_100 PF12899.7 AFI84833.1 - 0.047 12.3 0.0 0.094 11.4 0.0 1.5 1 1 0 1 1 1 0 Alkaline and neutral invertase FA_synthesis PF02504.15 AFI84834.1 - 1.1e-107 359.9 0.5 1.2e-107 359.7 0.5 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein PTA_PTB PF01515.19 AFI84834.1 - 1e-06 28.3 0.1 2e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Phosphate acetyl/butaryl transferase Ribosomal_L32p PF01783.23 AFI84835.1 - 9.1e-21 73.9 0.5 9.9e-21 73.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family YceD PF02620.17 AFI84836.1 - 3.6e-15 56.1 0.1 4.9e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD GATase_6 PF13522.6 AFI84837.1 - 5.4e-14 52.5 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AFI84837.1 - 1.1e-13 51.1 0.0 3.9e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AFI84837.1 - 2.9e-06 26.9 0.0 5.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AFI84837.1 - 4.1e-06 25.9 0.0 1.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Colicin_V PF02674.16 AFI84838.1 - 1.3e-38 132.2 18.7 1.6e-38 132.0 18.7 1.0 1 0 0 1 1 1 1 Colicin V production protein DUF2208 PF09973.9 AFI84838.1 - 0.011 15.4 4.6 0.016 14.8 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) NEMP PF10225.9 AFI84838.1 - 0.074 12.7 4.3 0.1 12.2 3.8 1.5 1 1 0 1 1 1 0 NEMP family Myc_target_1 PF15179.6 AFI84838.1 - 0.15 12.0 0.8 0.33 10.8 0.8 1.6 1 0 0 1 1 1 0 Myc target protein 1 EI24 PF07264.11 AFI84838.1 - 2.9 8.1 17.6 3.1 8.0 16.9 1.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SPOR PF05036.13 AFI84839.1 - 1.6e-12 47.6 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Sporulation related domain SARAF PF06682.12 AFI84839.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Lon_C PF05362.13 AFI84840.1 - 5.8e-94 313.4 0.9 5.8e-94 313.4 0.9 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AFI84840.1 - 1.3e-37 129.8 0.9 1.3e-37 129.8 0.9 2.0 3 0 0 3 3 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AFI84840.1 - 1.8e-19 70.5 0.8 3.5e-18 66.3 0.0 2.9 2 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI84840.1 - 4.5e-09 36.4 0.0 1.5e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 AFI84840.1 - 2.2e-06 26.9 0.0 4.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 AFI84840.1 - 6.3e-06 26.0 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 AFI84840.1 - 7.6e-05 23.2 4.0 0.0003 21.2 0.1 3.7 3 2 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 AFI84840.1 - 0.00019 21.2 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 AFI84840.1 - 0.00032 20.9 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 AFI84840.1 - 0.00036 20.8 1.2 0.043 14.1 0.0 3.7 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 AFI84840.1 - 0.00042 20.1 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 AFI84840.1 - 0.00073 19.4 0.0 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AFI84840.1 - 0.0029 18.2 0.4 0.013 16.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 AFI84840.1 - 0.003 17.9 0.2 0.11 12.9 0.0 3.4 4 0 0 4 4 4 1 RNA helicase NB-ARC PF00931.22 AFI84840.1 - 0.0036 16.5 1.3 0.0066 15.7 0.0 2.0 2 1 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 AFI84840.1 - 0.0045 17.0 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ECH_2 PF16113.5 AFI84840.1 - 0.0048 16.5 1.8 0.073 12.6 1.4 2.6 3 0 0 3 3 2 1 Enoyl-CoA hydratase/isomerase ABC_tran PF00005.27 AFI84840.1 - 0.006 17.1 0.4 0.13 12.7 0.0 2.9 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.12 AFI84840.1 - 0.0072 16.2 0.0 0.31 10.9 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_23 PF13476.6 AFI84840.1 - 0.015 15.8 9.2 1.4 9.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 AFI84840.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase TIP49 PF06068.13 AFI84840.1 - 0.023 13.9 1.2 0.084 12.1 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_15 PF13175.6 AFI84840.1 - 0.025 14.3 1.9 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 AFI84840.1 - 0.068 12.7 0.4 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AFI84840.1 - 0.069 13.2 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AFI84840.1 - 0.078 12.7 0.2 0.5 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 AFI84840.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 AFI84840.1 - 0.093 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 AFI84840.1 - 0.094 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 AFI84840.1 - 0.16 12.1 0.2 1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain MutS_III PF05192.18 AFI84840.1 - 0.16 12.1 0.6 0.63 10.2 0.4 2.1 1 1 0 1 1 1 0 MutS domain III AAA_19 PF13245.6 AFI84840.1 - 0.32 11.3 2.7 0.32 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain Phage_GP20 PF06810.11 AFI84840.1 - 2.2 8.1 10.9 0.6 9.9 6.4 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 MCU PF04678.13 AFI84840.1 - 3.3 7.8 5.5 8.7 6.4 5.5 1.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DUF5446 PF17522.2 AFI84840.1 - 4 7.7 9.8 1 9.6 5.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) AAA_2 PF07724.14 AFI84841.1 - 1.6e-47 161.8 0.0 2.3e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 AFI84841.1 - 2.3e-17 62.8 0.3 2.3e-17 62.8 0.3 2.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AFI84841.1 - 1.3e-16 61.2 0.0 2.7e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI84841.1 - 3.5e-07 30.3 0.2 4.5e-06 26.7 0.1 2.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AFI84841.1 - 6.7e-07 29.7 0.6 6.6e-06 26.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 AFI84841.1 - 3.3e-06 26.9 0.1 9.6e-06 25.4 0.1 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 AFI84841.1 - 2e-05 24.1 0.2 0.0033 16.8 0.1 3.0 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AFI84841.1 - 5.7e-05 22.9 0.0 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 AFI84841.1 - 9e-05 21.7 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 AFI84841.1 - 0.00021 21.7 0.1 0.00072 20.0 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 AFI84841.1 - 0.00021 21.4 0.0 0.00049 20.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 AFI84841.1 - 0.00031 20.3 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AFI84841.1 - 0.00063 19.8 0.2 0.0014 18.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 AFI84841.1 - 0.0013 18.1 0.1 0.0024 17.1 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AFI84841.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 AFI84841.1 - 0.0017 18.9 0.0 0.0041 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI84841.1 - 0.0019 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 AFI84841.1 - 0.0019 17.9 0.1 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AFI84841.1 - 0.0027 17.9 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AFI84841.1 - 0.0093 15.3 1.2 1.5 8.1 0.1 2.5 1 1 1 2 2 2 1 KaiC ABC_tran PF00005.27 AFI84841.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 AFI84841.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AFI84841.1 - 0.016 15.6 0.0 0.046 14.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 AFI84841.1 - 0.018 15.3 0.1 0.062 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AFI84841.1 - 0.02 14.8 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 AFI84841.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AFI84841.1 - 0.034 13.6 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ResIII PF04851.15 AFI84841.1 - 0.041 13.9 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 AFI84841.1 - 0.041 13.6 2.0 0.32 10.8 2.0 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 AFI84841.1 - 0.046 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PduV-EutP PF10662.9 AFI84841.1 - 0.063 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 AFI84841.1 - 0.067 12.9 0.1 0.26 11.0 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 AFI84841.1 - 0.086 13.2 0.5 2.1 8.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 AFI84841.1 - 0.12 12.8 2.0 0.27 11.7 1.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 AFI84841.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 AFI84841.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.22 AFI84841.1 - 0.16 12.0 0.3 0.34 11.0 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase AAA_25 PF13481.6 AFI84841.1 - 0.17 11.4 0.2 0.58 9.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_8 PF12780.7 AFI84841.1 - 0.2 10.9 0.0 0.52 9.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 CLP_protease PF00574.23 AFI84842.1 - 5.6e-88 293.6 0.2 7.3e-88 293.2 0.2 1.1 1 0 0 1 1 1 1 Clp protease Trigger_N PF05697.13 AFI84843.1 - 8.7e-36 123.4 2.4 8.7e-36 123.4 2.4 2.5 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 AFI84843.1 - 1.9e-31 109.3 7.1 1.9e-31 109.3 7.1 3.4 4 0 0 4 4 4 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 AFI84843.1 - 4.4e-10 39.7 0.5 1.7e-09 37.9 0.5 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HDOD PF08668.12 AFI84844.1 - 1.6e-37 128.9 1.8 3.3e-37 127.9 1.8 1.5 1 0 0 1 1 1 1 HDOD domain GAF_3 PF13492.6 AFI84844.1 - 6.9e-05 23.2 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AFI84844.1 - 0.00022 21.8 0.0 0.00063 20.4 0.0 1.8 2 0 0 2 2 2 1 GAF domain Asp_protease PF09668.10 AFI84844.1 - 0.025 14.4 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease 5-nucleotidase PF06189.12 AFI84845.1 - 1.3e-115 385.0 0.0 4.3e-115 383.2 0.0 1.7 1 1 1 2 2 2 1 5'-nucleotidase NERD PF08378.11 AFI84846.1 - 1.1e-05 25.9 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Nuclease-related domain Cation_efflux PF01545.21 AFI84847.1 - 5.8e-37 127.4 18.3 7.1e-37 127.1 18.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AFI84847.1 - 3.5e-22 78.3 0.5 5.6e-22 77.7 0.5 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MARVEL PF01284.23 AFI84847.1 - 4.3 7.4 12.2 1.9 8.5 0.4 2.8 2 1 1 3 3 3 0 Membrane-associating domain PGM_PMM_I PF02878.16 AFI84848.1 - 9.6e-36 122.5 0.1 1.7e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AFI84848.1 - 8.7e-32 109.7 0.0 1.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AFI84848.1 - 1.2e-12 48.3 0.1 3e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AFI84848.1 - 3.1e-05 24.0 0.0 8.5e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Maf PF02545.14 AFI84849.1 - 3.7e-43 147.3 0.0 4.2e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NADPH_Ox PF08414.10 AFI84849.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase DUF3306 PF11748.8 AFI84850.1 - 0.013 16.4 0.4 0.015 16.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) CHDCT2 PF08074.11 AFI84850.1 - 0.021 15.0 0.7 0.027 14.7 0.4 1.3 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain SRP54_N PF02881.19 AFI84850.1 - 0.037 14.3 0.1 0.056 13.7 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain SesA PF17107.5 AFI84850.1 - 0.047 13.9 0.3 0.099 12.8 0.2 1.5 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases APH PF01636.23 AFI84851.1 - 2.4e-28 99.7 1.0 3.2e-28 99.3 1.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 AFI84851.1 - 6.5e-05 22.4 0.5 0.00022 20.6 0.2 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 AFI84851.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 AFI84851.1 - 0.021 14.4 0.1 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase NTP_transferase PF00483.23 AFI84852.1 - 5.1e-22 78.7 0.0 2.6e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI84852.1 - 7e-10 39.5 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AFI84852.1 - 0.18 11.5 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase OTCace PF00185.24 AFI84853.1 - 2.7e-53 180.2 0.2 6.5e-53 179.0 0.2 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AFI84853.1 - 6.2e-53 178.8 0.1 1.5e-52 177.6 0.0 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminotran_3 PF00202.21 AFI84854.1 - 1.3e-114 383.0 0.1 1.7e-114 382.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AFI84854.1 - 4.1e-05 23.0 0.3 8.9e-05 21.9 0.1 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AFI84854.1 - 0.038 13.1 0.0 0.07 12.3 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II Sod_Fe_C PF02777.18 AFI84856.1 - 5.8e-41 138.8 0.3 9.6e-40 134.9 0.1 2.5 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AFI84856.1 - 3.8e-36 123.4 0.8 6.4e-36 122.7 0.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acetyltransf_1 PF00583.25 AFI84857.1 - 3.1e-14 53.2 0.0 4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AFI84857.1 - 1.9e-13 50.5 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AFI84857.1 - 1.1e-11 45.0 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AFI84857.1 - 1.5e-07 31.3 0.1 2.4e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AFI84857.1 - 7.3e-07 29.4 0.0 8.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AFI84857.1 - 2.6e-05 24.9 0.0 3.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AFI84857.1 - 0.00012 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AFI84857.1 - 0.0026 17.8 0.0 0.004 17.3 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 AFI84857.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase GNAT_acetyltran PF12746.7 AFI84857.1 - 0.023 14.3 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_9 PF13527.7 AFI84857.1 - 0.032 14.3 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CdiA_C PF18451.1 AFI84857.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain DNA_III_psi PF03603.13 AFI84858.1 - 1.4e-22 80.2 2.5 1.7e-22 80.0 2.5 1.1 1 0 0 1 1 1 1 DNA polymerase III psi subunit MOEP19 PF16005.5 AFI84858.1 - 0.029 14.4 0.0 0.087 12.8 0.0 1.8 1 1 0 1 1 1 0 KH-like RNA-binding domain DUF2458 PF10454.9 AFI84858.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) HMGL-like PF00682.19 AFI84859.1 - 3.6e-102 341.4 0.6 6.2e-102 340.7 0.6 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AFI84859.1 - 4.1e-38 130.3 1.2 8e-38 129.3 1.2 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain CDP-OH_P_transf PF01066.21 AFI84861.1 - 6e-13 49.4 3.2 6e-13 49.4 3.2 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase IlvN PF07991.12 AFI84862.1 - 9.8e-72 239.9 0.7 1.4e-71 239.4 0.7 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AFI84862.1 - 4.8e-65 218.2 0.7 6.3e-65 217.8 0.7 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AFI84862.1 - 5.5e-06 25.9 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AFI84862.1 - 1.8e-05 25.2 0.2 3.9e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AFI84862.1 - 0.00021 21.5 0.1 0.00039 20.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 AFI84862.1 - 0.0006 19.5 0.4 0.0018 17.9 0.4 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 AFI84862.1 - 0.0038 17.3 0.2 0.0069 16.5 0.1 1.5 2 0 0 2 2 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 AFI84862.1 - 0.004 17.6 0.0 0.011 16.2 0.0 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding PDH PF02153.17 AFI84862.1 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase AlaDh_PNT_N PF05222.15 AFI84862.1 - 0.01 16.1 0.2 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain GARS_N PF02844.15 AFI84862.1 - 0.017 15.9 0.1 0.11 13.3 0.0 2.2 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain NAD_Gly3P_dh_N PF01210.23 AFI84862.1 - 0.053 13.5 0.3 3 7.8 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AFI84862.1 - 0.084 13.7 0.1 0.17 12.7 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.9 AFI84862.1 - 0.1 12.5 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Rossmann-like domain Nitro_FeMo-Co PF02579.17 AFI84862.1 - 0.14 12.5 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor ALS_ss_C PF10369.9 AFI84863.1 - 2.1e-28 98.3 1.1 4.1e-26 91.0 0.3 2.2 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT_5 PF13710.6 AFI84863.1 - 1.7e-17 63.0 0.0 5e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 AFI84863.1 - 1e-13 50.8 0.3 2.2e-13 49.7 0.2 1.7 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AFI84863.1 - 0.012 16.1 0.3 0.032 14.8 0.3 1.7 1 0 0 1 1 1 0 ACT domain Csm2_III-A PF03750.13 AFI84863.1 - 0.077 13.8 0.1 0.26 12.2 0.1 1.8 1 1 0 1 1 1 0 Csm2 Type III-A CompInhib_SCIN PF11546.8 AFI84863.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Gaa1 PF04114.14 AFI84863.1 - 0.17 10.9 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component TPP_enzyme_N PF02776.18 AFI84864.1 - 4e-61 205.6 0.1 7.9e-60 201.4 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AFI84864.1 - 4.9e-55 185.5 0.0 3.4e-52 176.3 0.0 2.9 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AFI84864.1 - 1.2e-49 167.5 0.0 3e-49 166.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AFI84864.1 - 0.00078 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Amidohydro_2 PF04909.14 AFI84865.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase DJ-1_PfpI PF01965.24 AFI84866.1 - 1.3e-17 64.1 0.0 2.8e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AFI84866.1 - 1.8e-07 31.0 0.0 3.9e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like Rotamase_3 PF13616.6 AFI84867.1 - 7.1e-22 78.1 0.0 1.2e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AFI84867.1 - 8.4e-21 74.8 0.0 9.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AFI84867.1 - 3.4e-07 31.1 0.0 3.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Helicase_C_2 PF13307.6 AFI84868.1 - 6e-29 101.4 0.0 1.1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 AFI84868.1 - 2.5e-08 33.7 0.0 4.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 AFI84868.1 - 1.5e-07 31.6 0.2 3.2e-06 27.3 0.2 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AFI84868.1 - 1.4e-05 24.9 3.6 0.00025 20.8 0.1 3.2 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI84868.1 - 0.0046 17.3 0.0 0.02 15.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 AFI84868.1 - 0.047 14.0 0.1 13 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain SWI2_SNF2 PF18766.1 AFI84868.1 - 0.15 11.8 0.3 0.76 9.4 0.3 2.2 1 1 0 1 1 1 0 SWI2/SNF2 ATPase 2-Hacid_dh_C PF02826.19 AFI84869.1 - 1.2e-52 177.9 0.0 1.7e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AFI84869.1 - 9.5e-33 112.7 0.1 1.1e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 AFI84869.1 - 7.7e-07 29.3 0.1 2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 AFI84869.1 - 6.6e-05 23.4 0.3 0.00053 20.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 AFI84869.1 - 0.00029 20.4 0.0 0.00089 18.9 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_8 PF13450.6 AFI84869.1 - 0.00086 19.5 0.1 0.0029 17.8 0.1 1.9 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 AFI84869.1 - 0.0012 19.0 0.1 0.0032 17.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 AFI84869.1 - 0.0089 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 AFI84869.1 - 0.013 15.7 0.8 0.18 12.0 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 AFI84869.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 AFI84869.1 - 0.066 13.7 0.2 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain HI0933_like PF03486.14 AFI84869.1 - 0.077 11.7 0.3 0.13 10.9 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 AFI84869.1 - 0.13 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PfkB PF00294.24 AFI84870.1 - 1.6e-34 119.6 0.1 2e-34 119.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AFI84870.1 - 4.9e-06 26.1 0.0 7.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DHHA1 PF02272.19 AFI84871.1 - 1.4e-25 90.3 0.0 2.3e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 AFI84871.1 - 3.4e-21 75.5 0.0 5.5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 AFI84871.1 - 2.1e-08 34.3 0.0 4.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 DHH family Glyco_transf_4 PF13439.6 AFI84871.1 - 0.011 15.8 0.0 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Bac_DnaA PF00308.18 AFI84873.1 - 3.3e-24 86.0 0.0 5.6e-24 85.2 0.0 1.3 1 1 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 AFI84873.1 - 8.1e-09 35.4 0.0 1.8e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 AFI84873.1 - 2.7e-05 24.6 0.4 8.5e-05 23.0 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 AFI84873.1 - 5.1e-05 23.1 0.0 6.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AFI84873.1 - 5.6e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AFI84873.1 - 7.7e-05 22.7 0.0 0.00062 19.7 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AFI84873.1 - 0.00013 22.2 0.1 0.002 18.4 0.0 2.5 1 1 2 3 3 3 1 AAA domain RNA_helicase PF00910.22 AFI84873.1 - 0.00065 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 AFI84873.1 - 0.0063 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 AFI84873.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 AFI84873.1 - 0.022 14.7 0.1 0.33 10.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_5 PF07728.14 AFI84873.1 - 0.029 14.4 0.0 0.12 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 AFI84873.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 AFI84873.1 - 0.039 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AFI84873.1 - 0.045 13.8 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF5615 PF18480.1 AFI84873.1 - 0.056 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) AFG1_ATPase PF03969.16 AFI84873.1 - 0.06 12.2 0.1 0.17 10.7 0.1 1.7 1 1 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 AFI84873.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 AFI84873.1 - 0.097 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 AFI84873.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 AFI84873.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 AFI84873.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AI-2E_transport PF01594.16 AFI84874.1 - 2.9e-65 220.6 30.3 3.5e-65 220.3 30.3 1.0 1 0 0 1 1 1 1 AI-2E family transporter Ribonuc_L-PSP PF01042.21 AFI84874.1 - 0.22 11.5 0.0 0.37 10.8 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease L-PSP CDP-OH_P_transf PF01066.21 AFI84875.1 - 5.5e-09 36.7 0.1 5.5e-09 36.7 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gemini_mov PF01708.16 AFI84875.1 - 2.6 7.8 6.1 1.5 8.7 3.3 1.9 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF2066 PF09839.9 AFI84876.1 - 1.8e-67 227.1 5.9 2.4e-67 226.7 5.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2066) AIRS_C PF02769.22 AFI84877.1 - 8.3e-38 130.0 0.1 1.3e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AFI84877.1 - 1.7e-15 57.5 0.4 2.7e-15 56.8 0.4 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2482 PF10655.9 AFI84877.1 - 0.04 14.4 0.1 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Formyl_trans_N PF00551.19 AFI84878.1 - 2.1e-63 213.3 0.1 2.4e-63 213.1 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase SIS PF01380.22 AFI84878.1 - 0.016 15.0 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 SIS domain RMMBL PF07521.12 AFI84878.1 - 0.025 14.5 0.1 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain Peptidase_C50 PF03568.17 AFI84878.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 DUF3108 PF11306.8 AFI84879.1 - 2.4e-33 116.0 0.1 2.7e-33 115.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3108) DUF4579 PF15158.6 AFI84879.1 - 0.047 13.4 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) NUDIX PF00293.28 AFI84880.1 - 1.7e-11 44.3 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CdiI_N PF18228.1 AFI84880.1 - 0.0025 17.6 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 CdiI N-terminal domain Aldose_epim PF01263.20 AFI84881.1 - 1.8e-48 165.4 0.0 2.1e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FKBP_C PF00254.28 AFI84882.1 - 4.7e-12 46.1 0.0 6.9e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Iso_dh PF00180.20 AFI84883.1 - 0.017 14.3 0.0 0.018 14.2 0.0 1.0 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase PseudoU_synth_2 PF00849.22 AFI84884.1 - 1.5e-16 60.9 0.0 4.4e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase tRNA_Me_trans PF03054.16 AFI84886.1 - 1.6e-134 448.2 0.0 1.9e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 AFI84886.1 - 2e-08 33.7 0.0 5.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 AFI84886.1 - 8.8e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 AFI84886.1 - 0.0016 18.0 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AFI84886.1 - 0.0017 18.1 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 AFI84886.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.6 1 1 0 1 1 1 0 PP-loop family S8_pro-domain PF16470.5 AFI84886.1 - 0.018 15.8 0.0 15 6.5 0.0 2.7 3 0 0 3 3 3 0 Peptidase S8 pro-domain Rotavirus_VP7 PF05868.11 AFI84886.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 DUF489 PF04356.12 AFI84887.1 - 5e-71 238.7 1.5 5.7e-71 238.5 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DDE_Tnp_1_3 PF13612.6 AFI84888.1 - 7.6e-80 266.4 0.1 1.1e-79 265.9 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI84888.1 - 3.6e-22 79.1 0.8 1.1e-20 74.2 0.8 2.1 1 1 0 1 1 1 1 Transposase DDE domain Aconitase_2_N PF06434.13 AFI84889.1 - 6.9e-101 336.1 0.0 1e-100 335.5 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 AFI84889.1 - 1.4e-62 210.3 0.1 2.7e-62 209.4 0.1 1.5 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 AFI84889.1 - 7.7e-40 137.3 0.0 4.8e-38 131.3 0.0 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Ketoacyl-synt_C PF02801.22 AFI84889.1 - 0.099 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain PAS_7 PF12860.7 AFI84889.1 - 0.19 11.9 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 PAS fold Lyase_1 PF00206.20 AFI84890.1 - 3.2e-68 230.4 0.0 4.5e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 AFI84890.1 - 2.7e-51 172.5 0.1 1.3e-50 170.3 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal MetOD2 PF18548.1 AFI84890.1 - 0.0017 18.4 0.0 0.0069 16.5 0.0 2.0 2 0 0 2 2 2 1 Metanogen output domain 2 BLI1 PF17324.2 AFI84890.1 - 0.088 13.5 0.5 0.2 12.4 0.5 1.5 1 0 0 1 1 1 0 BLOC-1 interactor 1 DUF1494 PF07379.11 AFI84891.1 - 0.015 15.2 0.1 0.033 14.0 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) Secretin_N PF03958.17 AFI84892.1 - 5.2e-05 23.6 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain Aldolase PF01081.19 AFI84892.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase Nitroreductase PF00881.24 AFI84893.1 - 1.2e-33 116.6 0.4 1.4e-33 116.3 0.4 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AFI84893.1 - 1.9e-09 37.4 0.2 0.00014 21.5 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase GGDEF PF00990.21 AFI84894.1 - 1.1e-41 142.3 0.4 2.8e-41 141.0 0.1 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AFI84894.1 - 0.0014 18.9 0.3 0.0094 16.2 0.0 2.3 2 1 0 2 2 2 1 GGDEF-like domain DUF5394 PF17372.2 AFI84894.1 - 0.078 12.5 1.0 0.11 12.1 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5394) FliG_N PF14842.6 AFI84894.1 - 0.86 10.2 4.7 4 8.0 0.3 2.7 3 0 0 3 3 3 0 FliG N-terminal domain Arginosuc_synth PF00764.19 AFI84895.1 - 4.4e-156 520.0 0.0 5.1e-156 519.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.21 AFI84895.1 - 0.00052 19.8 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AFI84895.1 - 0.00058 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC CDC48_N PF02359.18 AFI84895.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain MethyltransfD12 PF02086.15 AFI84896.1 - 1.8e-43 149.1 0.4 2.4e-43 148.7 0.4 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase UPF0020 PF01170.18 AFI84896.1 - 0.0086 15.8 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Pyr_redox_2 PF07992.14 AFI84897.1 - 2.3e-61 207.6 1.8 3.1e-61 207.2 1.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AFI84897.1 - 1.6e-33 115.3 0.0 6e-33 113.4 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AFI84897.1 - 6.8e-20 71.4 1.7 1.1e-14 54.8 0.1 3.8 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Biotin_lipoyl PF00364.22 AFI84897.1 - 1.1e-19 70.0 5.8 2e-19 69.2 4.7 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Pyr_redox_3 PF13738.6 AFI84897.1 - 9.7e-13 48.0 0.6 1.4e-11 44.3 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AFI84897.1 - 7.6e-09 35.4 0.2 1.5e-08 34.4 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Biotin_lipoyl_2 PF13533.6 AFI84897.1 - 6.9e-08 32.2 2.6 7.9e-06 25.6 0.6 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like NAD_binding_8 PF13450.6 AFI84897.1 - 1.2e-07 31.9 7.6 5.2e-06 26.6 0.2 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AFI84897.1 - 2.1e-05 23.9 4.2 0.015 14.6 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AFI84897.1 - 3.9e-05 22.9 4.5 6.6e-05 22.2 0.3 2.7 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 AFI84897.1 - 4.2e-05 22.8 2.6 4.2e-05 22.8 2.6 3.3 2 1 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 AFI84897.1 - 0.00012 21.8 1.5 2 7.9 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AFI84897.1 - 0.00052 18.8 6.8 0.0018 17.1 0.2 3.4 3 1 1 4 4 4 1 HI0933-like protein GCV_H PF01597.19 AFI84897.1 - 0.0014 18.5 0.8 0.0034 17.2 0.8 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein Thi4 PF01946.17 AFI84897.1 - 0.0016 17.8 0.2 0.0084 15.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HlyD_3 PF13437.6 AFI84897.1 - 0.0088 16.7 3.5 0.13 13.0 0.1 3.0 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 AFI84897.1 - 0.019 14.2 0.1 0.059 12.6 0.1 1.8 1 1 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 AFI84897.1 - 0.028 14.4 2.8 0.76 9.8 1.9 3.2 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain UDPG_MGDP_dh_N PF03721.14 AFI84897.1 - 0.042 13.4 1.0 0.7 9.4 0.1 2.9 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AFI84897.1 - 0.043 13.2 0.0 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PYNP_C PF07831.13 AFI84897.1 - 0.066 12.9 0.6 0.42 10.3 0.2 2.4 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Peptidase_M23 PF01551.22 AFI84897.1 - 0.11 12.7 0.2 0.86 9.9 0.1 2.5 1 1 1 2 2 2 0 Peptidase family M23 FAD_binding_3 PF01494.19 AFI84897.1 - 0.13 11.5 3.5 0.35 10.1 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 AFI84897.1 - 0.22 10.3 0.3 1.2 7.9 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase TFX_C PF14601.6 AFI84897.1 - 0.22 11.5 2.3 0.55 10.2 0.6 2.5 3 0 0 3 3 2 0 DNA_binding protein, TFX, C-term 3HCDH_N PF02737.18 AFI84897.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.5 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-oxoacid_dh PF00198.23 AFI84898.1 - 9.9e-81 270.6 0.0 1.5e-80 270.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AFI84898.1 - 1.6e-20 72.7 5.4 3.3e-20 71.7 5.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AFI84898.1 - 7.6e-15 55.0 0.1 3.5e-14 52.8 0.0 2.2 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AFI84898.1 - 7.8e-06 25.6 1.4 3.9e-05 23.4 0.3 2.5 2 1 1 3 3 3 1 Biotin-lipoyl like GCV_H PF01597.19 AFI84898.1 - 0.00046 20.1 1.1 0.00046 20.1 1.1 2.1 1 1 1 2 2 2 1 Glycine cleavage H-protein RnfC_N PF13375.6 AFI84898.1 - 0.0049 16.8 2.9 0.054 13.5 1.5 2.9 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AFI84898.1 - 0.031 13.5 0.2 0.13 11.5 0.1 1.8 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Peptidase_M23 PF01551.22 AFI84898.1 - 0.056 13.6 0.1 0.19 11.9 0.1 1.9 1 1 0 1 1 1 0 Peptidase family M23 Glutaredoxin PF00462.24 AFI84898.1 - 0.058 13.6 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 Glutaredoxin HlyD_3 PF13437.6 AFI84898.1 - 0.085 13.6 1.1 2.1 9.1 1.1 2.4 1 1 0 1 1 1 0 HlyD family secretion protein PDH_E1_M PF17831.1 AFI84899.1 - 1e-113 378.6 0.2 1.6e-113 378.0 0.2 1.3 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 AFI84899.1 - 2.8e-14 52.8 0.1 5.1e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AFI84899.1 - 0.00028 20.7 0.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Ferric_reduct PF01794.19 AFI84900.1 - 3.6e-20 72.3 8.5 6.9e-20 71.4 8.5 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Oxidored_molyb PF00174.19 AFI84901.1 - 1.8e-28 99.3 0.0 2.6e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TAT_signal PF10518.9 AFI84901.1 - 0.034 14.0 1.0 0.068 13.0 1.0 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DoxX PF07681.12 AFI84902.1 - 7.6e-18 64.9 1.5 7.6e-18 64.9 1.5 1.7 2 0 0 2 2 2 1 DoxX Cytomega_TRL10 PF06084.11 AFI84902.1 - 0.052 13.6 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein GETHR PF05671.11 AFI84903.1 - 0.0012 18.2 11.3 0.62 9.5 0.2 3.1 3 0 0 3 3 3 3 GETHR pentapeptide repeat (5 copies) DUF3379 PF11859.8 AFI84903.1 - 0.21 10.9 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Sigma70_r4_2 PF08281.12 AFI84904.1 - 1.4e-12 47.1 0.5 2.1e-11 43.3 0.0 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI84904.1 - 3.4e-12 46.0 0.5 5.9e-12 45.2 0.5 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI84904.1 - 1.2e-08 34.4 0.0 2.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI84904.1 - 2.3e-08 34.1 0.4 3.6e-08 33.5 0.4 1.2 1 0 0 1 1 1 1 ECF sigma factor ASXH PF13919.6 AFI84904.1 - 0.01 15.9 0.6 0.018 15.1 0.2 1.8 1 1 0 1 1 1 0 Asx homology domain DUF1492 PF07374.11 AFI84904.1 - 0.046 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) HTH_28 PF13518.6 AFI84904.1 - 0.065 13.4 0.4 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain zf-HC2 PF13490.6 AFI84905.1 - 1.2e-09 38.2 0.2 1.8e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger ArfGap PF01412.18 AFI84905.1 - 0.069 13.2 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF1244 PF06844.11 AFI84906.1 - 6.8e-33 112.6 1.0 9.7e-33 112.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1244) Terminase_4 PF05119.12 AFI84906.1 - 0.0049 17.3 0.1 0.0055 17.1 0.1 1.3 1 1 0 1 1 1 1 Phage terminase, small subunit ABC_tran PF00005.27 AFI84907.1 - 2.6e-60 202.9 0.0 8.1e-31 107.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 AFI84907.1 - 3.6e-39 133.1 1.9 8.5e-19 67.9 0.1 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AFI84907.1 - 1.7e-13 50.5 0.0 1.3e-05 24.8 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AFI84907.1 - 4.4e-13 49.7 1.4 0.0027 17.6 0.1 3.4 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AFI84907.1 - 4.7e-10 39.9 1.6 6.5e-05 23.2 0.3 3.5 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AFI84907.1 - 5.1e-06 26.2 0.3 1.6 8.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 AFI84907.1 - 2.2e-05 24.9 1.9 0.028 14.8 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 AFI84907.1 - 0.00018 21.5 0.1 0.54 10.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 AFI84907.1 - 0.00025 20.7 0.1 0.48 10.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 AFI84907.1 - 0.0003 21.2 0.8 0.22 11.9 0.1 3.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AFI84907.1 - 0.0026 18.1 0.0 0.46 10.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 AFI84907.1 - 0.0028 17.6 0.2 0.62 10.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 AFI84907.1 - 0.0045 16.7 0.2 0.047 13.4 0.0 2.6 3 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 AFI84907.1 - 0.0051 16.3 0.1 1.1 8.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 AFI84907.1 - 0.007 15.8 0.2 1.2 8.5 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AFI84907.1 - 0.0072 16.1 2.1 3.2 7.4 0.0 3.1 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_5 PF07728.14 AFI84907.1 - 0.011 15.7 0.8 1.8 8.5 0.1 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 AFI84907.1 - 0.02 14.6 0.3 3.4 7.3 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 AFI84907.1 - 0.024 14.3 0.1 7.1 6.3 0.1 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 AFI84907.1 - 0.039 13.3 0.3 10 5.4 0.0 2.4 2 0 0 2 2 2 0 KaiC PRK PF00485.18 AFI84907.1 - 0.082 12.6 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 AFI84907.1 - 0.089 12.8 0.6 0.3 11.1 0.2 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AFI84907.1 - 0.12 12.1 0.1 9.1 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AFI84907.1 - 0.14 12.3 0.0 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 AFI84907.1 - 0.15 11.2 0.3 1.2 8.3 0.1 2.4 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.6 AFI84907.1 - 0.48 10.9 1.3 37 4.7 0.6 2.6 3 1 0 3 3 2 0 AAA domain BPD_transp_1 PF00528.22 AFI84908.1 - 2.7e-26 92.4 9.8 2.7e-26 92.4 9.8 3.9 4 0 0 4 4 4 2 Binding-protein-dependent transport system inner membrane component DUF4271 PF14093.6 AFI84908.1 - 6.9 6.5 20.1 0.13 12.2 9.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) LYTB PF02401.18 AFI84909.1 - 1.4e-91 306.5 0.1 1.6e-91 306.3 0.1 1.0 1 0 0 1 1 1 1 LytB protein DUF1363 PF07101.11 AFI84909.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) ETF_alpha PF00766.19 AFI84909.1 - 0.081 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain PDT PF00800.18 AFI84910.1 - 2.5e-63 213.2 0.3 2.5e-63 213.2 0.3 1.5 2 0 0 2 2 2 1 Prephenate dehydratase CM_2 PF01817.21 AFI84910.1 - 2.7e-22 78.9 2.3 5.5e-22 77.9 2.3 1.5 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 AFI84910.1 - 4.8e-11 42.2 0.0 1.7e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 ACT domain Filament PF00038.21 AFI84910.1 - 0.039 13.5 1.7 0.057 13.0 1.7 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF948 PF06103.11 AFI84910.1 - 0.063 13.5 0.6 0.19 12.0 0.6 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) G_path_suppress PF15991.5 AFI84910.1 - 0.42 10.7 2.7 0.78 9.8 2.7 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor Lge1 PF11488.8 AFI84910.1 - 0.57 10.4 2.4 1.1 9.4 2.4 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DivIC PF04977.15 AFI84910.1 - 0.57 10.0 4.0 1.3 8.9 4.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Aminotran_5 PF00266.19 AFI84911.1 - 1.3e-58 198.7 0.0 1.5e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DNA_topoisoIV PF00521.20 AFI84912.1 - 9.3e-156 519.0 0.0 1.2e-155 518.7 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AFI84912.1 - 2.1e-78 257.6 7.0 1.5e-15 56.4 0.2 6.3 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller IKI3 PF04762.12 AFI84912.1 - 0.0035 15.4 0.1 0.73 7.7 0.0 2.2 1 1 1 2 2 2 2 IKI3 family Ins134_P3_kin_N PF17927.1 AFI84912.1 - 0.13 12.7 0.1 0.51 10.8 0.1 2.0 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ABC_trans_aux PF03886.13 AFI84913.1 - 9.2e-12 44.8 0.1 1.2e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component LptE PF04390.12 AFI84913.1 - 0.0055 17.4 0.0 0.0081 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide-assembly Pribosyltran PF00156.27 AFI84914.1 - 1.7e-12 47.1 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AFI84914.1 - 0.0077 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AFI84914.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase MotY_N PF18393.1 AFI84915.1 - 1.4e-31 109.6 0.4 2e-31 109.1 0.4 1.2 1 0 0 1 1 1 1 MotY N-terminal domain OmpA PF00691.20 AFI84915.1 - 1.4e-20 73.4 1.0 4.2e-20 71.9 1.0 1.7 2 0 0 2 2 2 1 OmpA family Mesd PF10185.9 AFI84915.1 - 0.034 14.1 0.0 0.077 12.9 0.0 1.6 1 1 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Phos_pyr_kin PF08543.12 AFI84916.1 - 1.2e-59 201.7 0.0 1.8e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 AFI84916.1 - 9.8e-47 158.6 0.0 1.8e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase PfkB PF00294.24 AFI84916.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Carb_kinase PF01256.17 AFI84916.1 - 0.022 14.3 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate kinase HK PF02110.15 AFI84916.1 - 0.065 12.6 0.1 1.2 8.4 0.1 2.2 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family ThiG PF05690.14 AFI84917.1 - 3.9e-106 353.9 0.0 4.3e-106 353.7 0.0 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AFI84917.1 - 0.0099 15.4 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AFI84917.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PcrB PF01884.17 AFI84917.1 - 0.17 11.3 0.0 4 6.8 0.0 2.4 3 0 0 3 3 3 0 PcrB family ThiS PF02597.20 AFI84918.1 - 1.3e-12 48.2 0.0 1.5e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 ThiS family ThiS-like PF14453.6 AFI84918.1 - 0.017 15.1 0.3 0.068 13.2 0.3 1.8 1 1 0 1 1 1 0 ThiS-like ubiquitin Fer2_4 PF13510.6 AFI84918.1 - 0.03 14.4 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DAO PF01266.24 AFI84919.1 - 6e-32 111.6 0.1 7e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AFI84919.1 - 0.00017 21.7 0.1 0.00042 20.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 AFI84919.1 - 0.0013 18.4 0.2 0.0023 17.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 AFI84919.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 AFI84919.1 - 0.022 13.9 0.3 0.036 13.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 AFI84919.1 - 0.06 13.6 0.0 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 AFI84919.1 - 0.17 11.1 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 AFI84919.1 - 0.18 11.7 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_tail_X PF05489.12 AFI84919.1 - 0.18 11.5 0.0 0.51 10.1 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X GIDA PF01134.22 AFI84919.1 - 0.36 9.8 0.7 0.59 9.1 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiC_Rad_SAM PF01964.18 AFI84920.1 - 6.1e-198 657.8 0.0 7.2e-198 657.5 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AFI84920.1 - 8.4e-32 108.8 0.1 2e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 ThiC-associated domain Smr PF01713.21 AFI84921.1 - 8.6e-25 86.9 0.0 1.4e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Smr domain RlaP PF10127.9 AFI84922.1 - 1.5e-89 299.8 0.4 1.7e-89 299.7 0.4 1.0 1 0 0 1 1 1 1 RNA repair pathway DNA polymerase beta family Polbeta PF18765.1 AFI84922.1 - 0.0038 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase EAL PF00563.20 AFI84923.1 - 6.5e-58 196.1 0.1 4.9e-57 193.2 0.1 2.2 2 0 0 2 2 2 1 EAL domain Protoglobin PF11563.8 AFI84923.1 - 1e-26 93.7 2.3 2.9e-26 92.2 2.3 1.9 1 0 0 1 1 1 1 Protoglobin GGDEF PF00990.21 AFI84923.1 - 6.8e-24 84.4 4.4 1.3e-14 54.3 0.2 3.2 3 0 0 3 3 3 2 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 AFI84923.1 - 3.7e-12 46.7 0.0 9.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.7 AFI84923.1 - 1.1e-07 32.0 0.0 3.1e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AFI84923.1 - 4e-05 23.6 0.0 8.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI84923.1 - 5.6e-05 23.3 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 AFI84923.1 - 0.0036 17.9 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain PikAIV_N PF18605.1 AFI84923.1 - 0.04 13.5 0.9 0.079 12.6 0.9 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PAS_8 PF13188.7 AFI84923.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain GGDEF PF00990.21 AFI84924.1 - 2.6e-49 167.1 0.1 1.4e-48 164.6 0.0 2.1 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AFI84924.1 - 1.7e-15 57.0 0.1 3.9e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AFI84924.1 - 6.5e-15 55.3 0.0 1.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AFI84924.1 - 1.7e-14 53.8 0.0 4.7e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI84924.1 - 4.9e-14 52.5 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI84924.1 - 1.5e-06 28.1 0.0 1.4e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.6 AFI84924.1 - 3.7e-05 24.0 0.1 0.00016 22.0 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AFI84924.1 - 0.00058 20.2 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AFI84924.1 - 0.0026 18.4 0.1 0.011 16.4 0.1 2.0 2 0 0 2 2 2 1 GAF domain PAS_10 PF13596.6 AFI84924.1 - 0.12 12.9 0.0 0.52 10.9 0.0 1.9 1 1 0 2 2 2 0 PAS domain PAS_7 PF12860.7 AFI84924.1 - 0.14 12.3 0.0 0.68 10.1 0.0 2.2 2 1 0 2 2 2 0 PAS fold EAL PF00563.20 AFI84927.1 - 7.6e-71 238.4 0.0 1.4e-70 237.6 0.0 1.4 1 0 0 1 1 1 1 EAL domain PAS_3 PF08447.12 AFI84927.1 - 3.5e-50 168.2 0.9 2.5e-20 72.5 0.0 4.7 4 0 0 4 4 4 4 PAS fold GGDEF PF00990.21 AFI84927.1 - 2.1e-48 164.1 0.0 3.8e-48 163.3 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AFI84927.1 - 3.8e-27 94.5 0.1 1e-07 32.0 0.0 4.3 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 AFI84927.1 - 4.3e-24 84.8 0.0 9.5e-07 29.0 0.0 4.4 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 AFI84927.1 - 5.7e-23 81.3 0.0 3.3e-09 37.0 0.0 4.6 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 AFI84927.1 - 1.9e-14 53.3 0.1 0.00093 19.2 0.0 4.2 4 0 0 4 4 4 3 PAS domain PAS_12 PF18095.1 AFI84927.1 - 0.0072 16.0 0.0 0.077 12.6 0.0 2.6 3 0 0 3 3 3 1 UPF0242 C-terminal PAS-like domain RNase_P_Rpp14 PF01900.19 AFI84927.1 - 0.099 12.9 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Rpp14/Pop5 family PAS_11 PF14598.6 AFI84927.1 - 0.11 12.6 0.0 2 8.6 0.0 2.9 2 1 0 2 2 2 0 PAS domain V_ATPase_I_N PF18670.1 AFI84928.1 - 0.19 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain DUF711 PF05167.12 AFI84929.1 - 4.3e-170 566.0 7.2 5.3e-170 565.7 7.2 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) IL17R_D_N PF16742.5 AFI84929.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D ACT_6 PF13740.6 AFI84930.1 - 6.2e-20 71.0 3.6 1.3e-11 44.3 0.3 2.4 2 1 0 2 2 2 2 ACT domain ACT PF01842.25 AFI84930.1 - 2.4e-15 56.0 0.2 4.2e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 AFI84930.1 - 6.9e-13 49.0 0.1 6.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 AFI84930.1 - 7.1e-05 22.5 0.5 0.33 10.8 0.1 2.5 2 0 0 2 2 2 2 ACT domain Gamma_PGA_hydro PF05908.11 AFI84930.1 - 0.15 11.4 0.1 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Poly-gamma-glutamate hydrolase FlxA PF14282.6 AFI84931.1 - 4.4e-09 36.3 25.0 5.5e-09 35.9 25.0 1.1 1 0 0 1 1 1 1 FlxA-like protein AKNA PF12443.8 AFI84931.1 - 0.01 16.4 3.2 0.01 16.4 3.2 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF3375 PF11855.8 AFI84931.1 - 0.024 13.6 5.1 0.029 13.3 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Arm_APC_u3 PF16629.5 AFI84931.1 - 0.037 13.6 2.2 0.041 13.5 2.2 1.1 1 0 0 1 1 1 0 Armadillo-associated region on APC NAM-associated PF14303.6 AFI84931.1 - 0.14 12.9 10.2 0.18 12.5 10.2 1.0 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HeH PF12949.7 AFI84931.1 - 0.18 11.6 2.0 2.7 7.8 0.1 2.2 2 0 0 2 2 2 0 HeH/LEM domain DUF4407 PF14362.6 AFI84931.1 - 0.21 10.9 12.5 0.25 10.6 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tsg PF04668.12 AFI84931.1 - 0.36 11.5 3.8 0.51 11.0 3.8 1.2 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region Spt20 PF12090.8 AFI84931.1 - 1.4 8.5 14.0 1.7 8.2 14.0 1.1 1 0 0 1 1 1 0 Spt20 family LMBR1 PF04791.16 AFI84931.1 - 4.7 6.0 5.1 5 5.9 5.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2894 PF11445.8 AFI84932.1 - 0.033 14.6 0.3 0.043 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF4096 PF13340.6 AFI84933.1 - 0.0029 17.8 0.0 0.0036 17.5 0.0 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DUF3280 PF11684.8 AFI84934.1 - 9.7e-33 113.5 0.2 1.2e-32 113.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) Hydrolase_4 PF12146.8 AFI84935.1 - 3e-08 33.2 0.0 0.0031 16.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Palm_thioest PF02089.15 AFI84935.1 - 1.5e-06 28.3 0.0 1.5e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 AFI84935.1 - 1.8e-06 28.7 0.0 2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AFI84935.1 - 8.5e-05 22.3 0.0 0.00026 20.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 AFI84935.1 - 0.0015 18.0 0.1 0.0051 16.4 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 AFI84935.1 - 0.0041 17.0 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 AFI84935.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 AFI84935.1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 AFI84935.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase HTH_34 PF13601.6 AFI84935.1 - 0.19 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain GSHPx PF00255.19 AFI84936.1 - 4.6e-24 84.1 0.5 6.6e-24 83.6 0.5 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 AFI84936.1 - 0.00059 19.6 0.1 0.0013 18.5 0.1 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AFI84936.1 - 0.00086 19.2 0.1 0.0015 18.4 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Defensin_propep PF00879.18 AFI84936.1 - 0.099 12.9 0.4 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Defensin propeptide Thioredoxin PF00085.20 AFI84936.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin DUF3986 PF13143.6 AFI84936.1 - 0.13 13.2 0.0 0.21 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) ABC_tran PF00005.27 AFI84937.1 - 1.1e-59 200.8 0.0 3.6e-31 108.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AFI84937.1 - 1.4e-14 54.7 0.2 0.00078 19.3 0.0 4.0 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI84937.1 - 3.9e-12 46.1 0.0 3.8e-05 23.2 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain oligo_HPY PF08352.12 AFI84937.1 - 1.2e-10 41.8 0.0 2.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 AFI84937.1 - 1.7e-10 41.3 2.9 3.3e-05 24.2 0.4 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AFI84937.1 - 4.7e-08 33.6 2.3 2.6e-05 24.7 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 AFI84937.1 - 4.1e-06 26.8 0.3 0.13 12.2 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 AFI84937.1 - 6.8e-06 25.7 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 AFI84937.1 - 1.2e-05 24.9 0.0 0.21 11.1 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 AFI84937.1 - 2.2e-05 23.9 0.1 0.32 10.3 0.0 3.2 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AFI84937.1 - 4.3e-05 24.0 0.0 0.036 14.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AFI84937.1 - 5.5e-05 23.1 0.2 0.044 13.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 AFI84937.1 - 0.00027 21.0 0.6 0.48 10.4 0.1 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AFI84937.1 - 0.00027 20.6 0.0 0.069 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AFI84937.1 - 0.00039 20.2 0.3 1.4 8.6 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_33 PF13671.6 AFI84937.1 - 0.0005 20.2 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AFI84937.1 - 0.0008 19.2 0.1 0.31 10.8 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein TsaE PF02367.17 AFI84937.1 - 0.0012 18.9 0.1 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 AFI84937.1 - 0.0026 17.0 0.0 0.12 11.6 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain AAA_15 PF13175.6 AFI84937.1 - 0.0031 17.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 AFI84937.1 - 0.0047 16.7 0.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AFI84937.1 - 0.0057 17.2 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AFI84937.1 - 0.01 16.4 0.0 0.095 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 AFI84937.1 - 0.01 15.2 0.2 0.96 8.7 0.1 2.5 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 AFI84937.1 - 0.011 16.2 0.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase PH_18 PF18469.1 AFI84937.1 - 0.013 15.5 0.1 5 7.1 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain ATP-synt_ab PF00006.25 AFI84937.1 - 0.013 15.1 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 AFI84937.1 - 0.017 15.2 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 AFI84937.1 - 0.031 14.0 0.2 1.3 8.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 AFI84937.1 - 0.042 13.2 0.4 1.9 7.8 0.1 2.4 2 0 0 2 2 2 0 AIG1 family MMR_HSR1 PF01926.23 AFI84937.1 - 0.044 13.9 0.2 0.43 10.7 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase CbiA PF01656.23 AFI84937.1 - 0.048 13.7 0.1 2.9 7.9 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pox_A32 PF04665.12 AFI84937.1 - 0.064 12.7 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Roc PF08477.13 AFI84937.1 - 0.085 13.1 0.2 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 AFI84937.1 - 0.1 12.3 0.6 0.35 10.6 0.1 2.1 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 AFI84937.1 - 0.11 12.2 0.1 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TruB_C PF09142.11 AFI84937.1 - 0.12 12.2 0.0 4.8 7.0 0.0 2.7 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Zeta_toxin PF06414.12 AFI84937.1 - 0.14 11.4 0.1 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NIR_SIR_ferr PF03460.17 AFI84937.1 - 0.15 12.0 0.0 8.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain APS_kinase PF01583.20 AFI84937.1 - 0.17 11.7 0.3 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase ResIII PF04851.15 AFI84937.1 - 0.23 11.5 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1641 PF07849.11 AFI84937.1 - 0.38 10.7 2.8 0.97 9.4 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1641) Hpr_kinase_C PF07475.12 AFI84937.1 - 0.71 9.4 3.8 23 4.5 0.0 3.6 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain BPD_transp_1 PF00528.22 AFI84938.1 - 9.9e-22 77.6 12.0 9.9e-22 77.6 12.0 2.4 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AFI84938.1 - 9.7e-06 25.5 0.1 9.7e-06 25.5 0.1 3.9 3 1 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C DUF2633 PF11119.8 AFI84938.1 - 0.17 11.8 1.6 0.5 10.3 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) BPD_transp_1 PF00528.22 AFI84939.1 - 6.2e-26 91.3 29.7 8.4e-25 87.6 12.7 2.9 3 0 0 3 3 3 2 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AFI84940.1 - 2.7e-79 266.9 0.6 3.9e-79 266.3 0.1 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle Pup_ligase PF03136.15 AFI84940.1 - 0.042 12.9 1.0 0.065 12.2 1.0 1.2 1 0 0 1 1 1 0 Pup-ligase protein Ribosomal_S15 PF00312.22 AFI84940.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 Patatin PF01734.22 AFI84941.1 - 5.9e-21 75.6 0.2 3.6e-19 69.7 0.1 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase U3_snoRNA_assoc PF08297.11 AFI84942.1 - 0.0094 16.6 1.6 0.01 16.5 1.6 1.0 1 0 0 1 1 1 1 U3 snoRNA associated Lactamase_B PF00753.27 AFI84943.1 - 2.6e-14 53.7 0.1 1.1e-13 51.6 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AFI84943.1 - 5.1e-11 42.5 0.2 1.1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.12 AFI84943.1 - 0.0001 22.2 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AFI84943.1 - 0.0067 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AFI84943.1 - 0.085 12.7 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Beta-lactamase superfamily domain OAD_gamma PF04277.13 AFI84944.1 - 1.3e-18 67.3 0.0 2.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain PYC_OADA PF02436.18 AFI84945.1 - 2.8e-59 200.2 0.1 5.1e-59 199.4 0.1 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 AFI84945.1 - 1.1e-49 169.4 0.0 1.4e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AFI84945.1 - 1.4e-18 66.5 2.3 3.3e-18 65.3 2.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AFI84945.1 - 1.9e-14 53.2 1.2 2.8e-07 30.2 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AFI84945.1 - 3e-07 29.9 0.4 0.016 14.4 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI84945.1 - 1.1e-06 29.3 1.8 0.014 16.0 0.2 2.8 3 0 0 3 3 2 2 HlyD family secretion protein PTS_EIIA_1 PF00358.20 AFI84945.1 - 0.0056 16.4 0.5 1.5 8.6 0.0 2.9 2 1 1 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 YqfD PF06898.11 AFI84945.1 - 0.0095 14.8 5.9 0.18 10.6 0.4 2.3 1 1 1 2 2 2 2 Putative stage IV sporulation protein YqfD GCV_H PF01597.19 AFI84945.1 - 0.042 13.7 0.4 0.12 12.3 0.2 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 AFI84945.1 - 0.07 13.4 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Peptidase family M23 PASTA PF03793.19 AFI84945.1 - 0.11 12.4 0.3 0.47 10.3 0.3 2.1 1 1 1 2 2 2 0 PASTA domain RnfC_N PF13375.6 AFI84945.1 - 0.18 11.8 2.0 1 9.4 0.5 2.8 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain OAD_beta PF03977.13 AFI84946.1 - 1.4e-158 527.5 26.6 1.6e-158 527.3 26.6 1.0 1 0 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit SPT_ssu-like PF11779.8 AFI84946.1 - 0.21 11.3 0.6 14 5.4 0.1 2.8 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like S4_2 PF13275.6 AFI84949.1 - 2.3e-21 75.3 0.5 2.5e-21 75.2 0.5 1.0 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 AFI84949.1 - 4.8e-07 29.4 0.1 6.6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 S4 domain HTH_5 PF01022.20 AFI84950.1 - 4.2e-14 52.1 0.9 5.6e-14 51.7 0.9 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AFI84950.1 - 5.1e-05 23.2 0.1 6.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AFI84950.1 - 0.00071 19.4 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 AFI84950.1 - 0.00082 19.4 0.0 0.00099 19.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_36 PF13730.6 AFI84950.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 AFI84950.1 - 0.031 14.6 0.0 0.29 11.5 0.0 1.9 1 1 1 2 2 2 0 Transcriptional regulator MarR PF01047.22 AFI84950.1 - 0.032 14.2 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 AFI84950.1 - 0.037 13.9 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AFI84950.1 - 0.045 13.3 0.1 0.068 12.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PaaX PF07848.12 AFI84950.1 - 0.046 13.9 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein HTH_Crp_2 PF13545.6 AFI84950.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF4423 PF14394.6 AFI84950.1 - 0.056 13.2 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_9 PF08221.11 AFI84950.1 - 0.073 13.2 0.7 0.099 12.8 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain LMWPc PF01451.21 AFI84951.1 - 5.9e-21 75.3 0.0 7e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LpqV PF17301.2 AFI84951.1 - 0.021 15.0 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative lipoprotein LpqV Lipase_2 PF01674.18 AFI84951.1 - 0.081 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) SBF PF01758.16 AFI84952.1 - 1.6e-46 158.5 13.7 1.6e-46 158.5 13.7 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 AFI84952.1 - 1.9e-07 30.7 23.7 2e-07 30.7 21.7 1.8 1 1 1 2 2 2 1 SBF-like CPA transporter family (DUF4137) Gp_dh_C PF02800.20 AFI84953.1 - 1.8e-62 209.6 0.1 3.4e-62 208.7 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AFI84953.1 - 6.5e-30 103.5 1.5 2.6e-28 98.3 0.1 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 AFI84953.1 - 0.0036 17.4 0.6 0.06 13.5 0.0 3.0 2 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Imm1 PF14430.6 AFI84953.1 - 0.073 13.7 0.1 0.21 12.2 0.0 1.7 2 0 0 2 2 2 0 Immunity protein Imm1 2OG-FeII_Oxy_2 PF13532.6 AFI84954.1 - 4.1e-51 174.0 0.0 4.7e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_binding_1 PF01035.20 AFI84956.1 - 5.6e-31 106.5 0.1 8e-31 106.0 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Oxidored_FMN PF00724.20 AFI84958.1 - 4.3e-72 243.2 0.0 4.9e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tachykinin PF02202.16 AFI84958.1 - 0.04 13.8 0.9 0.11 12.4 0.9 1.8 1 0 0 1 1 1 0 Tachykinin family Na_H_Exchanger PF00999.21 AFI84959.1 - 8.1e-52 176.3 48.1 1e-51 176.0 48.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorC_HlyC PF03471.17 AFI84959.1 - 9.9e-13 47.9 0.0 8.2e-12 45.0 0.0 2.2 2 0 0 2 2 2 1 Transporter associated domain TrkA_C PF02080.21 AFI84959.1 - 7.5e-10 38.5 0.0 2.8e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 TrkA-C domain MarC PF01914.17 AFI84960.1 - 5.8e-54 182.6 14.5 6.6e-54 182.4 14.5 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein DUF5090 PF17009.5 AFI84960.1 - 7.7 6.4 14.4 0.14 12.1 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF305 PF03713.13 AFI84961.1 - 8.4e-11 42.2 0.5 1.2e-10 41.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF305) Ytca PF17090.5 AFI84961.1 - 0.024 15.1 4.5 0.056 14.0 4.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family Polysacc_synt_C PF14667.6 AFI84961.1 - 0.14 12.3 13.1 0.16 12.0 13.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF3216 PF11505.8 AFI84961.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Tetraspanin PF00335.20 AFI84961.1 - 0.94 9.1 7.1 0.5 10.0 0.5 2.0 2 0 0 2 2 2 0 Tetraspanin family VirB3 PF05101.13 AFI84961.1 - 3 8.1 12.1 0.98 9.7 8.7 1.9 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein IMS PF00817.20 AFI84962.1 - 1.5e-33 115.9 0.0 2.8e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family DUF4113 PF13438.6 AFI84962.1 - 7.6e-23 80.4 0.5 2e-22 79.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4113) IMS_C PF11799.8 AFI84962.1 - 5.2e-16 59.4 0.0 2.1e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AFI84962.1 - 0.00039 20.6 0.1 0.001 19.3 0.1 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.6 AFI84962.1 - 0.00047 20.7 0.0 0.0021 18.6 0.0 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 AFI84962.1 - 0.00062 19.6 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DUF4332 PF14229.6 AFI84962.1 - 0.012 15.8 0.1 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Peptidase_S24 PF00717.23 AFI84963.1 - 9.3e-10 38.3 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like SNARE_assoc PF09335.11 AFI84964.1 - 5.4e-10 39.8 6.0 5.4e-10 39.8 6.0 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3341 PF11821.8 AFI84964.1 - 0.29 10.7 2.6 1.3 8.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Ribosomal_S30AE PF02482.19 AFI84966.1 - 8.5e-08 32.9 0.1 1e-07 32.6 0.1 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein RuvC PF02075.17 AFI84966.1 - 0.0021 17.9 0.0 0.0024 17.8 0.0 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC GPW_gp25 PF04965.14 AFI84966.1 - 0.018 14.8 0.5 0.035 13.9 0.1 1.7 2 0 0 2 2 2 0 Gene 25-like lysozyme T3SS_basalb_I PF17001.5 AFI84966.1 - 0.11 13.1 0.3 2.5 8.7 0.0 2.0 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI EcoR124_C PF12008.8 AFI84967.1 - 2.3e-60 204.5 11.2 2.3e-60 204.5 11.2 3.3 2 1 0 2 2 2 1 Type I restriction and modification enzyme - subunit R C terminal SWI2_SNF2 PF18766.1 AFI84967.1 - 4.6e-60 203.1 2.7 4.6e-60 203.1 2.7 3.9 3 1 0 3 3 3 2 SWI2/SNF2 ATPase HSDR_N PF04313.14 AFI84967.1 - 1e-37 130.0 4.3 1e-37 130.0 4.3 2.8 3 0 0 3 3 3 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 AFI84967.1 - 4e-36 124.6 0.6 4e-36 124.6 0.6 3.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Polbeta PF18765.1 AFI84967.1 - 3.1e-12 46.4 0.1 3.8e-11 42.9 0.0 2.8 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AFI84967.1 - 2.5e-07 30.9 0.0 9e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain DEAD PF00270.29 AFI84967.1 - 2.6e-06 27.3 0.1 1.1e-05 25.3 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 AFI84967.1 - 0.0049 15.6 0.4 0.015 14.1 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain NTase_sub_bind PF08780.11 AFI84968.1 - 1.5e-40 138.1 2.0 1.7e-40 137.9 2.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase substrate binding protein like DUF86 PF01934.17 AFI84968.1 - 0.0041 17.0 0.3 0.0084 16.0 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF86 Methylase_S PF01420.19 AFI84969.1 - 2.9e-29 102.5 7.1 2.5e-16 60.4 6.3 2.1 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain INCENP_N PF12178.8 AFI84969.1 - 0.065 13.2 1.2 4.7 7.3 0.1 2.8 3 0 0 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF2443 PF10398.9 AFI84969.1 - 0.7 10.0 4.1 2.1 8.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) N6_Mtase PF02384.16 AFI84970.1 - 4e-110 368.0 0.0 5.3e-110 367.5 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AFI84970.1 - 1.5e-17 64.5 0.8 1.5e-17 64.5 0.8 2.6 3 0 0 3 3 3 1 HsdM N-terminal domain MTS PF05175.14 AFI84970.1 - 2.5e-06 27.2 0.0 5.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AFI84970.1 - 2.6e-05 24.1 0.0 6.8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6-adenineMlase PF10237.9 AFI84970.1 - 0.0019 18.0 0.8 0.014 15.2 0.3 2.2 1 1 1 2 2 2 1 Probable N6-adenine methyltransferase Methyltransf_25 PF13649.6 AFI84970.1 - 0.0051 17.5 0.0 0.026 15.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 AFI84970.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa UPF0020 PF01170.18 AFI84970.1 - 0.011 15.4 0.0 0.29 10.8 0.0 2.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Eco57I PF07669.11 AFI84970.1 - 0.045 14.3 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Pox_F15 PF04596.12 AFI84970.1 - 0.056 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Poxvirus protein F15 Glyco_hydro_47 PF01532.20 AFI84970.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 47 Peptidase_C54 PF03416.19 AFI84970.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C54 Virulence_RhuM PF13310.6 AFI84971.1 - 5.2e-25 88.1 0.2 7.9e-25 87.5 0.2 1.3 1 0 0 1 1 1 1 Virulence protein RhuM family Fic PF02661.18 AFI84971.1 - 4.7e-09 37.0 0.0 1.8e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family HTH_37 PF13744.6 AFI84971.1 - 0.03 14.3 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AFI84971.1 - 0.062 13.3 0.0 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Mrr_cat PF04471.12 AFI84972.1 - 6.5e-34 116.4 0.0 1.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Mrr_N PF14338.6 AFI84972.1 - 1.4e-29 102.1 0.1 6.3e-29 99.9 0.0 2.0 2 0 0 2 2 2 1 Mrr N-terminal domain Mrr_cat_2 PF13156.6 AFI84972.1 - 1.8e-12 47.3 0.0 3.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease HTH_45 PF14947.6 AFI84972.1 - 0.0095 15.9 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix Arabinose_bd PF12625.7 AFI84973.1 - 3.1e-23 82.8 0.0 6e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 AFI84973.1 - 1.1e-09 38.4 0.4 2.4e-09 37.3 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AFI84973.1 - 1.6e-06 28.1 0.1 0.052 13.7 0.1 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sec7 PF01369.20 AFI84973.1 - 0.21 11.3 2.7 1.1 8.9 0.2 2.8 3 0 0 3 3 3 0 Sec7 domain GGDEF PF00990.21 AFI84974.1 - 8.1e-26 90.7 1.5 1.2e-25 90.2 0.9 1.5 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AFI84974.1 - 0.031 14.6 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 GGDEF-like domain DctQ PF04290.12 AFI84974.1 - 0.14 12.1 9.2 0.032 14.1 4.3 2.3 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Zip PF02535.22 AFI84974.1 - 0.19 10.9 1.0 0.26 10.5 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter 7TMR-DISM_7TM PF07695.11 AFI84974.1 - 0.33 10.8 6.6 0.57 10.0 6.6 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling TonB_dep_Rec PF00593.24 AFI84975.1 - 6.6e-44 151.6 25.4 6.6e-44 151.6 25.4 2.2 1 1 1 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 AFI84975.1 - 3.2e-31 108.7 10.4 3.9e-31 108.4 3.7 2.3 1 1 1 2 2 2 2 Outer membrane protein beta-barrel family Plug PF07715.15 AFI84975.1 - 1e-14 55.0 0.7 2.5e-14 53.7 0.7 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Phytase PF02333.15 AFI84976.1 - 1.5e-94 317.1 0.0 1.7e-82 277.4 0.2 2.3 2 1 0 2 2 2 2 Phytase Lactonase PF10282.9 AFI84976.1 - 0.0033 16.7 0.0 0.14 11.4 0.0 2.8 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller SdiA-regulated PF06977.11 AFI84976.1 - 0.095 11.9 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 SdiA-regulated MotA_ExbB PF01618.16 AFI84977.1 - 2e-38 131.0 1.2 3.1e-38 130.4 0.9 1.6 1 1 0 1 1 1 1 MotA/TolQ/ExbB proton channel family HemY_N PF07219.13 AFI84977.1 - 0.14 12.4 0.4 0.14 12.4 0.4 2.1 2 1 1 3 3 3 0 HemY protein N-terminus ExbD PF02472.16 AFI84978.1 - 1.1e-26 93.5 0.7 1.3e-26 93.3 0.7 1.1 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_C PF03544.14 AFI84979.1 - 6.6e-16 58.5 0.0 2.5e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Nrap_D2 PF17403.2 AFI84979.1 - 0.053 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DUF839 PF05787.13 AFI84980.1 - 7e-172 573.2 1.8 8.1e-172 573.0 1.8 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) TAT_signal PF10518.9 AFI84980.1 - 0.071 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PD40 PF07676.12 AFI84980.1 - 0.11 12.5 0.4 65 3.6 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat QSregVF PF13652.6 AFI84981.1 - 0.00078 19.4 0.0 0.0013 18.7 0.0 1.3 1 1 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor DUF1574 PF07611.11 AFI84981.1 - 0.0055 16.1 0.0 0.0062 15.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) DUF1506 PF07405.11 AFI84981.1 - 0.012 15.8 0.1 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) HTH_18 PF12833.7 AFI84982.1 - 1.2e-18 67.1 0.2 1.2e-18 67.1 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 AFI84982.1 - 1.3e-13 50.6 0.9 2.8e-09 36.9 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_N PF06719.13 AFI84982.1 - 1.1e-09 38.1 0.3 1.9e-09 37.3 0.3 1.4 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_10 PF04967.12 AFI84982.1 - 0.011 15.5 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain DALR_1 PF05746.15 AFI84982.1 - 0.049 13.8 0.2 0.092 12.9 0.1 1.4 1 1 0 1 1 1 0 DALR anticodon binding domain YdiH PF15930.5 AFI84982.1 - 0.05 13.8 0.2 0.16 12.2 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function BAR_3 PF16746.5 AFI84982.1 - 0.079 12.6 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 BAR domain of APPL family SelR PF01641.18 AFI84983.1 - 1.7e-46 157.2 0.0 2.1e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 SelR domain PMSR PF01625.21 AFI84984.1 - 4.7e-56 189.2 0.0 5.4e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase NAD_binding_6 PF08030.12 AFI84984.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Polbeta PF18765.1 AFI84986.1 - 1.4e-08 34.7 0.1 2.4e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AFI84986.1 - 1.2e-07 31.9 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain MarR_2 PF12802.7 AFI84986.1 - 0.00027 20.7 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 AFI84986.1 - 0.0059 16.6 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Phage_rep_O PF04492.13 AFI84986.1 - 0.011 16.2 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage replication protein O Fip1 PF05182.13 AFI84987.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Fip1 motif DUF4238 PF14022.6 AFI84988.1 - 4.1e-14 52.7 0.0 2.7e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4238) UvrD_C PF13361.6 AFI84989.1 - 1.5e-27 96.9 0.0 5.9e-14 52.2 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AFI84989.1 - 4.3e-14 52.1 0.0 1.3e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain NERD PF08378.11 AFI84989.1 - 2.1e-11 44.2 0.0 7.9e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 Nuclease-related domain AAA_19 PF13245.6 AFI84989.1 - 3.5e-09 37.1 0.0 1e-08 35.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AFI84989.1 - 6.5e-08 32.6 0.7 0.0022 17.8 0.0 3.2 1 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 AFI84989.1 - 8.3e-07 28.8 0.5 0.018 14.6 0.1 2.8 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 AFI84989.1 - 2.1e-06 27.6 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 AFI84989.1 - 0.00088 18.9 0.0 0.029 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AFI84989.1 - 0.013 15.5 0.0 0.067 13.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 AFI84989.1 - 0.016 15.6 0.0 0.064 13.6 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain DEAD PF00270.29 AFI84989.1 - 0.054 13.2 0.0 0.26 11.1 0.1 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 AFI84989.1 - 0.15 12.3 0.3 0.89 9.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AFI84989.1 - 0.26 10.5 0.8 0.71 9.1 0.3 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SmpB PF01668.18 AFI84990.1 - 1.5e-59 200.0 1.1 1.7e-59 199.8 1.1 1.0 1 0 0 1 1 1 1 SmpB protein SNF PF00209.18 AFI84991.1 - 1.4e-45 156.0 35.9 8.3e-24 84.2 21.0 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family Polyketide_cyc PF03364.20 AFI84992.1 - 1e-31 109.8 0.0 1.2e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AFI84992.1 - 7.8e-09 35.9 0.0 9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ub-RnfH PF03658.14 AFI84993.1 - 4.5e-37 126.3 0.1 5.5e-37 126.0 0.1 1.1 1 0 0 1 1 1 1 RnfH family Ubiquitin DUF455 PF04305.14 AFI84994.1 - 2e-98 328.9 0.0 2.3e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) BPD_transp_1 PF00528.22 AFI84995.1 - 7.1e-29 100.9 24.3 2.7e-28 99.0 21.5 2.4 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component Rhodanese PF00581.20 AFI84996.1 - 5e-21 75.2 0.0 6.4e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF442 PF04273.13 AFI84996.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative phosphatase (DUF442) PepSY PF03413.19 AFI84997.1 - 0.068 13.7 0.4 11 6.7 0.1 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF692 PF05114.13 AFI84998.1 - 5.2e-108 360.2 0.1 5.9e-108 360.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) DUF2063 PF09836.9 AFI84999.1 - 1.2e-27 96.0 0.1 2.3e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain PqqD PF05402.12 AFI84999.1 - 8.5e-05 22.8 0.0 0.00031 21.0 0.0 1.9 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) FWWh PF14922.6 AFI84999.1 - 0.0087 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function Aldolase PF01081.19 AFI85000.1 - 3.3e-73 245.3 1.4 3.7e-73 245.1 1.4 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase HMGL-like PF00682.19 AFI85000.1 - 0.0048 16.5 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like YqjK PF13997.6 AFI85000.1 - 0.031 14.5 0.0 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 YqjK-like protein IMPDH PF00478.25 AFI85000.1 - 0.064 12.2 0.2 0.084 11.9 0.2 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ILVD_EDD PF00920.21 AFI85001.1 - 8.6e-161 536.1 0.0 1e-160 535.8 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Methyltransf_4 PF02390.17 AFI85002.1 - 1.1e-59 200.8 0.0 1.3e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 AFI85002.1 - 0.0087 16.7 0.0 0.018 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AFI85002.1 - 0.0088 15.6 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 AFI85002.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Toluene_X PF03349.16 AFI85003.1 - 3.1e-119 398.4 7.6 3.6e-119 398.2 7.6 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) OMP_b-brl PF13505.6 AFI85003.1 - 1.5e-08 35.0 18.2 0.00032 20.9 9.3 4.1 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 AFI85003.1 - 3.5e-06 27.1 5.5 0.052 13.5 1.3 4.1 2 2 2 4 4 4 2 Protein of unknown function (DUF2490) Legionella_OMP PF05150.12 AFI85003.1 - 8.1e-05 21.7 3.6 0.00079 18.4 0.4 2.6 1 1 0 2 2 2 1 Legionella pneumophila major outer membrane protein precursor Autotransporter PF03797.19 AFI85003.1 - 0.00029 20.6 7.5 0.096 12.3 0.8 3.5 3 1 0 3 3 3 2 Autotransporter beta-domain Porin_4 PF13609.6 AFI85003.1 - 0.0028 17.5 0.1 0.0028 17.5 0.1 3.4 1 1 1 2 2 2 2 Gram-negative porin MtrB_PioB PF11854.8 AFI85003.1 - 0.0051 15.2 5.9 0.018 13.4 3.5 2.6 1 1 1 2 2 2 1 Putative outer membrane beta-barrel porin, MtrB/PioB YadA_anchor PF03895.15 AFI85003.1 - 2.5 8.3 14.3 8.9 6.5 0.0 6.2 8 0 0 8 8 8 0 YadA-like membrane anchor domain AMP-binding PF00501.28 AFI85004.1 - 8.1e-95 317.9 0.0 1e-94 317.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Death PF00531.22 AFI85004.1 - 0.05 13.8 0.2 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 Death domain ARID PF01388.21 AFI85004.1 - 0.067 13.9 0.2 0.38 11.4 0.0 2.2 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain Mur_ligase_M PF08245.12 AFI85005.1 - 8.3e-09 35.7 0.0 3.6e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Sulfatase PF00884.23 AFI85005.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Sulfatase Mur_ligase_C PF02875.21 AFI85005.1 - 0.054 13.8 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Carboxyl_trans PF01039.22 AFI85006.1 - 1.2e-17 63.8 0.2 2.5e-17 62.7 0.1 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain zf-ACC PF17848.1 AFI85006.1 - 4.7e-11 42.5 7.8 7.5e-11 41.9 7.8 1.3 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain Cys_rich_KTR PF14205.6 AFI85006.1 - 0.0014 18.3 0.7 0.0035 17.1 0.7 1.6 1 0 0 1 1 1 1 Cysteine-rich KTR FYDLN_acid PF09538.10 AFI85006.1 - 0.02 15.6 0.9 0.032 14.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Putative_G5P PF17426.2 AFI85006.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P IBR PF01485.21 AFI85006.1 - 0.12 12.6 2.4 0.22 11.8 2.4 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 AFI85006.1 - 0.13 12.2 3.4 0.27 11.2 3.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 AFI85006.1 - 0.29 11.3 5.8 0.56 10.4 5.8 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 AFI85006.1 - 0.87 9.2 4.3 1.6 8.3 4.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 AFI85006.1 - 1.1 9.3 4.3 2.8 8.0 4.3 1.6 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-NADH-PPase PF09297.11 AFI85006.1 - 1.8 8.3 6.6 5.5 6.7 1.6 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Trp_syntA PF00290.20 AFI85007.1 - 1.3e-91 306.0 0.3 1.5e-91 305.8 0.3 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PcrB PF01884.17 AFI85007.1 - 0.00039 20.0 0.4 0.00092 18.7 0.1 1.8 2 0 0 2 2 2 1 PcrB family His_biosynth PF00977.21 AFI85007.1 - 0.0005 19.6 0.0 0.0016 17.9 0.1 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein Peripla_BP_6 PF13458.6 AFI85007.1 - 0.02 14.6 0.0 0.14 11.8 0.0 2.0 1 1 1 2 2 2 0 Periplasmic binding protein ParA PF10609.9 AFI85007.1 - 0.069 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase PALP PF00291.25 AFI85008.1 - 9.8e-47 159.8 1.6 1.2e-46 159.5 1.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRAI PF00697.22 AFI85009.1 - 3.7e-16 59.5 0.0 3.8e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase baeRF_family11 PF18855.1 AFI85009.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 PRAI PF00697.22 AFI85010.1 - 6.4e-22 78.3 0.0 7.7e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase OHCU_decarbox PF09349.10 AFI85010.1 - 0.13 12.7 0.0 0.58 10.6 0.0 1.8 1 1 1 2 2 2 0 OHCU decarboxylase PseudoU_synth_1 PF01416.20 AFI85011.1 - 1.7e-40 137.8 0.0 1.6e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase LysM PF01476.20 AFI85012.1 - 8.8e-05 22.5 0.1 0.00034 20.6 0.0 2.1 2 1 0 2 2 2 1 LysM domain TPR_19 PF14559.6 AFI85012.1 - 0.00016 22.2 20.8 0.027 15.0 0.6 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 AFI85012.1 - 0.0015 19.2 9.4 0.0084 16.9 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 AFI85012.1 - 0.0036 17.1 0.0 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat SlyX PF04102.12 AFI85012.1 - 0.025 15.2 15.1 1.8 9.2 1.3 3.5 2 0 0 2 2 2 0 SlyX Stevor PF17410.2 AFI85012.1 - 0.15 11.6 0.7 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame TPR_7 PF13176.6 AFI85012.1 - 0.16 12.1 0.9 0.53 10.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RIFIN PF02009.16 AFI85012.1 - 0.24 11.2 5.8 0.055 13.4 1.6 2.1 2 0 0 2 2 2 0 Rifin TPR_12 PF13424.6 AFI85012.1 - 0.27 11.6 0.0 0.27 11.6 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnn_1N PF07989.11 AFI85012.1 - 0.39 10.9 5.6 0.18 11.9 1.0 2.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Semialdhyde_dhC PF02774.18 AFI85013.1 - 3.8e-62 209.6 0.0 5.3e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AFI85013.1 - 4e-31 108.0 0.1 8.6e-31 106.9 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 AFI85013.1 - 0.05 14.3 0.1 0.12 13.1 0.1 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 AFI85013.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Iso_dh PF00180.20 AFI85014.1 - 1.4e-136 455.3 0.0 1.6e-136 455.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aconitase_C PF00694.19 AFI85015.1 - 3.9e-33 114.6 0.0 5.9e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain OmpA PF00691.20 AFI85016.1 - 3.6e-18 65.7 0.0 1.3e-16 60.7 0.0 2.8 2 1 1 3 3 3 1 OmpA family MotB_plug PF13677.6 AFI85016.1 - 1.7e-15 56.3 2.6 4e-15 55.2 2.6 1.6 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB ABC2_membrane_3 PF12698.7 AFI85016.1 - 0.039 13.0 1.0 0.079 12.1 0.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Cache_3-Cache_2 PF17201.4 AFI85016.1 - 0.085 12.1 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain ExbD PF02472.16 AFI85016.1 - 1.3 9.2 8.3 4.6 7.4 0.8 2.6 2 1 0 2 2 2 0 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 AFI85017.1 - 1.3e-25 89.6 0.8 1.3e-25 89.6 0.8 2.2 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family DUF2148 PF09918.9 AFI85017.1 - 0.087 12.9 0.5 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) SBP_bac_5 PF00496.22 AFI85018.1 - 1.2e-51 175.9 0.0 2.8e-51 174.7 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle adh_short_C2 PF13561.6 AFI85019.1 - 2.4e-87 292.4 1.9 2.7e-87 292.2 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AFI85019.1 - 4.1e-20 72.1 0.3 5.2e-20 71.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 AFI85019.1 - 0.0017 17.8 0.2 0.62 9.4 0.0 2.1 1 1 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region KR PF08659.10 AFI85019.1 - 0.0059 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 KR domain SDF PF00375.18 AFI85020.1 - 5.7e-127 423.9 35.3 6.5e-127 423.8 35.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family HTH_19 PF12844.7 AFI85021.1 - 8.3e-08 32.1 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AFI85021.1 - 6.2e-07 29.4 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AFI85021.1 - 0.0001 22.6 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AFI85021.1 - 0.027 14.0 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HipA_C PF07804.12 AFI85022.1 - 1.7e-44 152.0 0.0 4e-44 150.8 0.0 1.5 1 1 1 2 2 2 1 HipA-like C-terminal domain Couple_hipA PF13657.6 AFI85022.1 - 9e-05 23.1 0.0 0.00025 21.7 0.0 1.7 1 0 0 1 1 1 1 HipA N-terminal domain Lys-AminoMut_A PF09043.11 AFI85022.1 - 0.099 11.1 0.1 0.17 10.3 0.1 1.3 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit SurA_N_3 PF13624.6 AFI85023.1 - 3.5e-53 179.7 0.2 3.5e-53 179.7 0.2 2.3 3 0 0 3 3 3 1 SurA N-terminal domain SurA_N_2 PF13623.6 AFI85023.1 - 2.4e-41 141.0 0.3 2.4e-41 141.0 0.3 2.5 3 0 0 3 3 3 1 SurA N-terminal domain Rotamase_2 PF13145.6 AFI85023.1 - 2.9e-30 105.6 7.7 3.9e-19 69.7 0.4 4.4 3 1 1 4 4 4 4 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AFI85023.1 - 1.5e-26 93.2 0.1 4.7e-26 91.6 0.1 1.9 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AFI85023.1 - 4.8e-25 88.4 1.0 3.7e-24 85.5 0.1 2.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain SurA_N PF09312.11 AFI85023.1 - 1.9e-06 27.9 0.5 1.9e-06 27.9 0.5 2.4 3 0 0 3 3 3 1 SurA N-terminal domain Bac_DNA_binding PF00216.21 AFI85024.1 - 2.6e-34 117.3 0.4 2.9e-34 117.1 0.4 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AFI85024.1 - 6.2e-08 32.8 0.0 6.6e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 AFI85024.1 - 1.8e-05 24.8 0.1 2.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 AFI85024.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 PT-TG PF14449.6 AFI85024.1 - 0.077 12.9 1.6 0.14 12.0 0.1 2.0 1 1 1 2 2 2 0 Pre-toxin TG HU-CCDC81_bac_1 PF18174.1 AFI85024.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 RrnaAD PF00398.20 AFI85025.1 - 2.7e-62 210.3 0.0 3e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 AFI85025.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RsmJ PF04378.13 AFI85025.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Methyltransf_25 PF13649.6 AFI85025.1 - 0.033 14.9 0.0 0.059 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PdxA PF04166.12 AFI85026.1 - 2.1e-108 362.1 0.0 2.4e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Rotamase PF00639.21 AFI85027.1 - 2.2e-49 166.4 0.0 1e-26 93.7 0.0 2.7 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AFI85027.1 - 5.5e-46 155.9 0.0 6.4e-29 100.8 0.0 2.4 1 1 1 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 AFI85027.1 - 8.4e-43 145.2 9.0 2.5e-42 143.7 9.0 1.9 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_2 PF13145.6 AFI85027.1 - 9.4e-17 62.0 1.6 8.9e-08 33.0 0.0 3.6 2 1 2 4 4 4 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AFI85027.1 - 4.1e-16 59.2 3.4 4.1e-16 59.2 3.4 2.7 4 0 0 4 4 4 1 SurA N-terminal domain SurA_N_2 PF13623.6 AFI85027.1 - 7.8e-09 35.5 2.5 7.8e-09 35.5 2.5 3.3 3 1 1 4 4 4 1 SurA N-terminal domain HycH PF07450.11 AFI85027.1 - 0.034 14.5 0.3 0.11 12.9 0.3 1.8 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH L_lactis_ph-MCP PF06673.11 AFI85027.1 - 0.063 12.3 0.4 3.8 6.4 0.0 3.0 2 1 1 3 3 3 0 Lactococcus lactis bacteriophage major capsid protein Nif11 PF07862.11 AFI85027.1 - 0.075 13.4 1.2 18 5.7 0.0 2.9 2 0 0 2 2 2 0 Nif11 domain Lipase_GDSL_2 PF13472.6 AFI85027.1 - 0.11 12.9 0.5 0.29 11.5 0.2 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF445 PF04286.12 AFI85027.1 - 0.46 10.2 7.7 1.8 8.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Nab1 PF04902.12 AFI85027.1 - 2.6 8.4 9.2 0.28 11.6 0.3 3.0 2 1 1 3 3 3 0 Conserved region in Nab1 DUF4011 PF13195.6 AFI85027.1 - 3.8 7.4 9.9 1.1e+03 -0.5 9.9 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) LptD PF04453.14 AFI85028.1 - 2.5e-104 349.6 15.2 6.7e-104 348.2 15.2 1.8 2 0 0 2 2 2 1 LPS transport system D OstA PF03968.14 AFI85028.1 - 1.2e-07 31.9 6.4 5.3e-06 26.6 6.4 2.6 1 1 0 1 1 1 1 OstA-like protein LptC PF06835.13 AFI85028.1 - 0.0019 17.8 1.3 0.0036 16.9 0.5 1.8 1 1 1 2 2 2 1 Lipopolysaccharide-assembly, LptC-related OstA_2 PF13100.6 AFI85028.1 - 0.061 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 OstA-like protein Endonuc_BglI PF14562.6 AFI85029.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI DUF4972 PF16342.5 AFI85029.1 - 0.017 14.8 0.5 0.65 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) DUF4874 PF16173.5 AFI85029.1 - 0.16 11.6 0.8 0.26 11.0 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4874) LptF_LptG PF03739.14 AFI85030.1 - 8e-62 209.1 2.4 9e-62 209.0 2.4 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Phage_holin_3_6 PF07332.11 AFI85030.1 - 1.3 9.0 13.8 1.3 9.1 1.4 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LptF_LptG PF03739.14 AFI85031.1 - 3.7e-61 207.0 2.3 4.4e-61 206.7 2.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG OATP PF03137.20 AFI85031.1 - 0.0095 14.3 1.0 0.56 8.4 1.0 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M17 PF00883.21 AFI85032.1 - 3.2e-123 411.0 0.0 4.2e-123 410.6 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AFI85032.1 - 4.9e-24 84.6 0.3 2.3e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain DNA_pol3_chi PF04364.13 AFI85033.1 - 1.2e-41 142.0 0.0 1.4e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC tRNA-synt_1 PF00133.22 AFI85034.1 - 2e-213 710.0 0.2 2.7e-212 706.3 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AFI85034.1 - 2.5e-43 147.7 0.1 4.2e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AFI85034.1 - 6e-19 68.1 5.5 1.2e-18 67.2 5.5 1.5 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 AFI85034.1 - 4e-15 55.5 5.4 5.4e-06 25.4 0.0 5.0 3 2 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AFI85034.1 - 1.2e-07 31.5 0.0 5.6e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AFI85034.1 - 0.027 13.8 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ABC_tran_CTD PF16326.5 AFI85034.1 - 0.24 11.7 4.5 0.62 10.4 4.5 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 AFI85034.1 - 4.3 7.2 5.9 12 5.8 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator UPF0061 PF02696.14 AFI85035.1 - 2.4e-140 468.4 0.0 3e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GSDH PF07995.11 AFI85036.1 - 1.8e-127 425.2 0.8 2.1e-127 425.0 0.8 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 AFI85036.1 - 0.07 12.7 0.0 1.2 8.6 0.0 2.3 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region GreA_GreB PF01272.19 AFI85037.1 - 1.5e-23 82.5 0.0 2.2e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 AFI85037.1 - 1.5e-20 73.1 1.1 2.3e-20 72.5 1.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal Tox-REase-7 PF15649.6 AFI85037.1 - 0.32 11.3 1.9 6.3 7.2 0.0 2.6 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 7 Mqo PF06039.15 AFI85038.1 - 1.6e-23 83.0 0.0 2.9e-23 82.2 0.0 1.4 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 AFI85038.1 - 5.9e-19 68.8 0.0 7.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AFI85038.1 - 0.00052 19.4 0.1 0.051 12.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AFI85038.1 - 0.004 16.4 2.2 0.18 11.0 2.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AFI85038.1 - 0.0079 14.9 0.3 0.031 13.0 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 AFI85038.1 - 0.04 13.9 0.2 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_L17 PF01196.19 AFI85038.1 - 0.2 12.6 1.0 0.61 11.0 0.0 2.3 4 0 0 4 4 4 0 Ribosomal protein L17 VWA PF00092.28 AFI85040.1 - 1.4e-12 48.2 0.0 2.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AFI85040.1 - 1.9e-09 38.1 0.0 1.1e-08 35.6 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 AFI85040.1 - 9.6e-09 35.4 0.2 2.7e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 AFI85040.1 - 0.0042 16.6 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 vWA-TerF-like PF10138.9 AFI85040.1 - 0.013 15.7 1.1 0.033 14.3 0.1 2.3 2 2 0 2 2 2 0 vWA found in TerF C terminus SBP_bac_11 PF13531.6 AFI85040.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein VWA_CoxE PF05762.14 AFI85040.1 - 0.1 11.9 0.8 0.36 10.2 0.0 2.2 2 1 0 2 2 2 0 VWA domain containing CoxE-like protein NPL PF17800.1 AFI85040.1 - 0.14 12.7 0.0 2.2 8.9 0.0 2.4 1 1 0 1 1 1 0 Nucleoplasmin-like domain Cys_Met_Meta_PP PF01053.20 AFI85041.1 - 3.1e-136 453.9 0.0 3.5e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AFI85041.1 - 3.9e-11 42.7 0.0 6e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AFI85041.1 - 8.6e-10 38.1 0.0 6.6e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AFI85041.1 - 5.1e-08 32.6 0.0 5.3e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 AFI85041.1 - 0.0091 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Tae4 PF14113.6 AFI85041.1 - 0.075 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 TonB_dep_Rec PF00593.24 AFI85042.1 - 9e-43 147.8 33.3 1.1e-42 147.5 33.3 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AFI85042.1 - 8.6e-25 87.4 1.6 1.3e-24 86.9 0.1 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain DUF4231 PF14015.6 AFI85043.1 - 7.3 7.1 6.8 2.6 8.6 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) GATase_3 PF07685.14 AFI85044.1 - 1.1e-33 116.5 0.0 1.5e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AFI85044.1 - 1.9e-12 47.4 0.0 4.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AFI85044.1 - 1.4e-11 44.6 0.1 1.8e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain SNO PF01174.19 AFI85044.1 - 0.01 15.7 0.1 0.025 14.4 0.0 1.6 2 0 0 2 2 2 0 SNO glutamine amidotransferase family PRK PF00485.18 AFI85044.1 - 0.059 13.1 0.0 9.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 AFI85044.1 - 0.072 12.7 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 AFI85044.1 - 0.077 13.3 0.8 9.6 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain DJ-1_PfpI PF01965.24 AFI85044.1 - 0.091 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family ResIII PF04851.15 AFI85044.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1611 PF07755.11 AFI85044.1 - 0.14 11.4 0.1 0.39 10.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Nitroreductase PF00881.24 AFI85045.1 - 3.2e-29 102.2 0.0 4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AFI85045.1 - 0.0037 16.9 0.0 1.3 8.5 0.0 2.6 2 1 1 3 3 3 2 Putative TM nitroreductase CobD_Cbib PF03186.13 AFI85046.1 - 8.9e-86 287.5 0.2 1.1e-85 287.2 0.2 1.1 1 0 0 1 1 1 1 CobD/Cbib protein AmpE PF17113.5 AFI85046.1 - 2e-12 47.0 0.6 3.2e-12 46.4 0.6 1.3 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE TPR_2 PF07719.17 AFI85046.1 - 0.093 12.9 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 AFI85047.1 - 2.7e-28 99.2 0.0 3.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II NAD_binding_7 PF13241.6 AFI85047.1 - 0.2 12.1 0.0 4.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding GATase_3 PF07685.14 AFI85048.1 - 1.9e-54 184.2 0.0 3.3e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AFI85048.1 - 4e-23 81.9 0.0 3.6e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AFI85048.1 - 1.8e-22 80.2 0.0 3.4e-22 79.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AFI85048.1 - 0.00035 20.5 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B GATase PF00117.28 AFI85048.1 - 0.13 12.0 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase class-I CobU PF02283.16 AFI85049.1 - 1e-60 204.1 0.0 1.2e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF3220 PF11516.8 AFI85049.1 - 0.083 13.1 0.2 0.48 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) DBI_PRT PF02277.17 AFI85050.1 - 4.7e-124 413.9 11.4 5.7e-124 413.6 11.4 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase MAAL_C PF07476.11 AFI85050.1 - 0.057 12.6 0.2 0.18 10.9 0.2 1.7 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus CobS PF02654.15 AFI85051.1 - 5.4e-48 163.9 21.0 6.1e-48 163.7 21.0 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase YscK PF06578.12 AFI85051.1 - 0.05 13.1 0.3 0.071 12.6 0.3 1.2 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) CobA_CobO_BtuR PF02572.15 AFI85052.1 - 5.1e-55 186.4 0.1 5.1e-55 186.4 0.1 1.4 2 0 0 2 2 2 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Co_AT_N PF12557.8 AFI85052.1 - 1.1e-08 34.7 6.2 2.1e-08 33.8 6.2 1.5 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal Hairpins PF04877.12 AFI85052.1 - 0.043 13.5 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 HrpZ AAA_2 PF07724.14 AFI85053.1 - 2.2e-54 184.1 0.1 1.5e-47 161.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AFI85053.1 - 1.5e-27 95.6 0.9 3.4e-27 94.4 0.9 1.6 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AFI85053.1 - 2.6e-25 89.4 0.0 1.1e-13 51.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AFI85053.1 - 4.5e-24 84.3 0.2 1.5e-23 82.6 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AFI85053.1 - 6.1e-20 71.6 0.0 4.6e-13 49.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 AFI85053.1 - 3.6e-14 52.6 0.8 1.5e-13 50.7 0.5 2.3 2 0 0 2 2 1 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 AFI85053.1 - 1.7e-13 51.4 7.2 1e-05 26.0 0.1 4.9 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 AFI85053.1 - 3.5e-10 40.3 2.5 0.0019 18.5 0.2 4.7 2 2 1 3 3 3 2 AAA domain TniB PF05621.11 AFI85053.1 - 4.5e-09 36.0 0.0 3.6e-06 26.5 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 AFI85053.1 - 2e-08 34.1 0.3 0.00053 19.7 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 AFI85053.1 - 4.4e-08 33.2 0.0 8.7e-05 22.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AFI85053.1 - 5.8e-07 29.1 0.3 0.088 12.2 0.0 3.9 2 2 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AFI85053.1 - 6.6e-07 29.2 2.6 0.28 10.9 0.0 4.4 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AFI85053.1 - 1.6e-06 27.7 0.0 0.047 13.2 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AFI85053.1 - 1.2e-05 25.9 0.0 0.15 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 AFI85053.1 - 2.2e-05 24.3 0.0 0.00032 20.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AFI85053.1 - 3.8e-05 23.5 0.1 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 AFI85053.1 - 6.8e-05 22.9 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AFI85053.1 - 7.5e-05 22.9 0.1 0.49 10.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 AFI85053.1 - 0.00014 21.8 0.2 0.0082 16.1 0.0 3.2 4 0 0 4 4 3 1 NACHT domain AAA_6 PF12774.7 AFI85053.1 - 0.0002 20.4 0.0 0.00069 18.7 0.0 1.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 AFI85053.1 - 0.00037 20.9 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ResIII PF04851.15 AFI85053.1 - 0.00054 20.0 0.0 1.2 9.1 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 AFI85053.1 - 0.00091 19.2 1.8 1.4 8.8 0.0 4.0 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AFI85053.1 - 0.0011 18.6 1.1 0.77 9.3 0.2 3.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 AFI85053.1 - 0.0012 18.1 0.2 0.24 10.5 0.0 3.0 3 1 1 4 4 4 1 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 AFI85053.1 - 0.0043 16.8 0.0 3.8 7.2 0.0 3.9 4 0 0 4 4 4 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 AFI85053.1 - 0.0065 16.4 0.0 2.4 8.0 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase SRP54 PF00448.22 AFI85053.1 - 0.0079 15.8 0.1 2.9 7.5 0.1 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Torsin PF06309.11 AFI85053.1 - 0.019 15.1 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Torsin AAA_28 PF13521.6 AFI85053.1 - 0.02 15.2 0.0 9 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 AFI85053.1 - 0.026 13.9 0.5 3.7 6.8 0.0 3.8 3 2 0 3 3 3 0 P-loop containing dynein motor region D4 Rad17 PF03215.15 AFI85053.1 - 0.042 13.8 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 AFI85053.1 - 0.042 13.6 0.1 17 5.3 0.1 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AFI85053.1 - 0.056 12.7 0.1 10 5.3 0.0 3.5 3 1 0 3 3 3 0 Zeta toxin Roc PF08477.13 AFI85053.1 - 0.15 12.3 0.0 4.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ClpS PF02617.17 AFI85054.1 - 4.7e-34 116.0 0.1 5.7e-34 115.8 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Glutaredoxin PF00462.24 AFI85055.1 - 2.1e-18 66.3 0.0 3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AFI85055.1 - 0.021 15.2 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Hydrolase PF00702.26 AFI85056.1 - 2.1e-17 64.1 0.4 3e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI85056.1 - 2.2e-15 57.6 0.0 3.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AFI85056.1 - 6.6e-12 45.7 3.8 1.6e-10 41.1 0.5 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AFI85056.1 - 5.3e-06 26.6 1.8 3.7e-05 23.9 1.8 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI85056.1 - 0.048 13.7 0.1 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 HAD-hyrolase-like Pyrophosphatase PF00719.19 AFI85057.1 - 3.4e-56 189.5 0.4 3.8e-56 189.3 0.4 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase FdsD PF11390.8 AFI85057.1 - 0.076 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD TauE PF01925.19 AFI85058.1 - 8.5e-52 176.1 40.9 9.8e-52 175.9 40.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE TssN PF17555.2 AFI85058.1 - 2.9 7.2 10.9 0.036 13.5 0.8 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssN MatE PF01554.18 AFI85059.1 - 1.1e-38 132.5 36.8 2.7e-24 85.6 15.3 2.5 2 1 1 3 3 3 2 MatE Phage_Integr_2 PF13009.6 AFI85059.1 - 0.054 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative phage integrase PseudoU_synth_2 PF00849.22 AFI85061.1 - 9e-23 81.1 0.0 2e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase Synapsin PF02078.16 AFI85061.1 - 0.082 13.2 0.1 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Synapsin, N-terminal domain DUF4124 PF13511.6 AFI85062.1 - 2.4e-13 50.2 0.2 2.4e-13 50.2 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4124) DUF4672 PF15716.5 AFI85062.1 - 0.011 15.3 1.8 0.016 14.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) MRP-S32 PF10210.9 AFI85062.1 - 0.035 14.7 0.4 0.035 14.7 0.4 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 MIF PF01187.18 AFI85063.1 - 6.1e-19 68.4 0.0 6.8e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase_2 PF14552.6 AFI85063.1 - 7.5e-05 22.8 0.0 0.00047 20.2 0.0 1.9 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase PF01361.21 AFI85063.1 - 0.0041 17.0 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 2 Tautomerase enzyme tRNA-synt_2b PF00587.25 AFI85064.1 - 8.6e-49 165.9 0.0 1.3e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 AFI85064.1 - 5.3e-28 97.6 0.1 9.1e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 AFI85064.1 - 1.5e-18 66.7 0.0 2.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TIR_2 PF13676.6 AFI85064.1 - 0.086 13.5 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 TIR domain Fumerase PF05681.14 AFI85065.1 - 8.3e-103 343.5 0.1 1.1e-102 343.1 0.1 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 AFI85065.1 - 2.4e-79 265.5 0.0 3.5e-79 264.9 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus CopD PF05425.13 AFI85066.1 - 1.9e-15 57.1 5.3 1.9e-15 57.1 5.3 1.8 2 0 0 2 2 2 1 Copper resistance protein D DUF1772 PF08592.11 AFI85066.1 - 0.0055 17.0 1.9 0.0071 16.7 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4149 PF13664.6 AFI85066.1 - 0.069 13.5 10.6 0.039 14.3 8.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4191 PF13829.6 AFI85066.1 - 0.13 11.5 3.7 0.21 10.9 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) UPF0093 PF03653.13 AFI85066.1 - 1.7 8.8 12.0 4.5 7.5 12.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0093) SLT PF01464.20 AFI85067.1 - 9.9e-28 96.2 0.1 1.3e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 AFI85067.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 Lysozyme-like SLT_2 PF13406.6 AFI85067.1 - 0.006 15.9 0.4 1.7 7.8 0.1 2.1 1 1 1 2 2 2 2 Transglycosylase SLT domain zf-CHC2 PF01807.20 AFI85067.1 - 0.032 14.0 0.1 0.083 12.7 0.0 1.7 2 0 0 2 2 2 0 CHC2 zinc finger DUF218 PF02698.17 AFI85068.1 - 9.3e-09 35.4 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain gag-asp_proteas PF13975.6 AFI85069.1 - 4e-23 81.8 0.2 3.9e-22 78.6 0.2 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AFI85069.1 - 7.1e-18 65.0 0.2 1.9e-17 63.7 0.2 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 AFI85069.1 - 0.0021 18.3 0.1 0.011 16.0 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Molydop_binding PF01568.21 AFI85069.1 - 0.021 14.8 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF533 PF04391.12 AFI85070.1 - 1.8e-64 216.6 8.4 2.2e-64 216.3 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF533) TerB PF05099.13 AFI85070.1 - 0.024 14.6 0.7 0.05 13.6 0.1 1.9 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF3318 PF11780.8 AFI85070.1 - 0.035 14.1 0.2 0.07 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) YtxH PF12732.7 AFI85070.1 - 0.09 13.3 1.7 0.3 11.7 1.7 2.0 1 0 0 1 1 1 0 YtxH-like protein SARAF PF06682.12 AFI85070.1 - 0.81 9.3 3.2 1.4 8.5 3.2 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Gly-zipper_YMGG PF13441.6 AFI85070.1 - 8.1 6.3 17.4 1.8 8.4 12.8 2.0 2 0 0 2 2 2 0 YMGG-like Gly-zipper E1-E2_ATPase PF00122.20 AFI85072.1 - 1.5e-50 171.2 1.7 1.5e-50 171.2 1.7 3.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AFI85072.1 - 4.5e-36 124.3 9.8 4.5e-36 124.3 9.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AFI85072.1 - 7.5e-23 81.9 4.2 4.1e-22 79.5 4.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AFI85072.1 - 1.9e-16 59.5 0.1 4.7e-16 58.2 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AFI85072.1 - 2.9e-14 52.9 0.0 5.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AFI85072.1 - 3.2e-07 30.4 2.1 8.6e-06 25.7 1.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI85072.1 - 0.0031 17.9 0.4 0.016 15.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.6 AFI85073.1 - 8.8e-10 38.8 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_2 PF03446.15 AFI85073.1 - 6.7e-06 26.4 0.0 9.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 AFI85073.1 - 0.0029 17.1 0.1 0.02 14.4 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0225 PF17775.1 AFI85074.1 - 1.8e-27 96.0 0.0 2.2e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AFI85074.1 - 8.2e-13 48.0 14.4 2.6e-07 30.4 4.0 2.2 2 0 0 2 2 2 2 SEC-C motif Acetyltransf_5 PF13444.6 AFI85075.1 - 5.4e-21 75.2 0.2 1.5e-20 73.8 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acyltransferase PF01553.21 AFI85075.1 - 2.3e-13 49.9 0.0 9.3e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase Asp_decarbox PF02261.16 AFI85076.1 - 1.7e-48 163.3 0.2 1.9e-48 163.1 0.2 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Pantoate_ligase PF02569.15 AFI85077.1 - 7.9e-99 330.2 0.1 8.8e-99 330.0 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase GNVR PF13807.6 AFI85077.1 - 0.011 15.6 0.7 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Bap31_Bap29_C PF18035.1 AFI85077.1 - 0.13 12.3 1.3 0.26 11.3 1.3 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain YjcZ PF13990.6 AFI85077.1 - 0.14 11.5 0.8 0.26 10.6 0.8 1.4 1 0 0 1 1 1 0 YjcZ-like protein Pantoate_transf PF02548.15 AFI85078.1 - 7.8e-113 376.1 0.6 8.9e-113 376.0 0.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 AFI85078.1 - 1.7e-05 24.8 0.4 9.5e-05 22.3 0.1 2.1 1 1 0 2 2 2 1 Asp/Glu/Hydantoin racemase PEP_mutase PF13714.6 AFI85078.1 - 0.012 15.0 0.7 0.038 13.5 0.7 1.9 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase dNK PF01712.19 AFI85079.1 - 3.1e-38 131.7 0.1 3.9e-38 131.4 0.1 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 AFI85079.1 - 1.9e-06 28.5 0.0 1.2e-05 25.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AFI85079.1 - 7.9e-06 26.1 0.0 0.00016 21.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 AFI85079.1 - 2e-05 24.4 0.0 0.0039 16.9 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 AFI85079.1 - 0.00021 21.7 0.0 0.0004 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AFI85079.1 - 0.00021 21.5 0.0 0.00048 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AFI85079.1 - 0.0034 17.3 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 AFI85079.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AFI85079.1 - 0.028 14.8 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 AFI85079.1 - 0.049 14.0 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 AFI85079.1 - 0.082 12.5 0.1 0.88 9.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 AFI85079.1 - 0.13 12.3 0.4 0.5 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 AFI85079.1 - 0.13 11.9 0.0 5 6.8 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase HPPK PF01288.20 AFI85080.1 - 1.4e-40 138.2 0.0 1.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PolyA_pol_arg_C PF12626.7 AFI85081.1 - 1.3e-44 151.1 2.5 2.4e-44 150.2 2.5 1.4 1 0 0 1 1 1 1 Polymerase A arginine-rich C-terminus PolyA_pol PF01743.20 AFI85081.1 - 8.8e-38 129.6 0.0 1.5e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AFI85081.1 - 1e-17 63.6 0.0 2.7e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A RNase_HII PF01351.18 AFI85082.1 - 4.5e-41 140.9 0.0 5.1e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII LpxB PF02684.15 AFI85083.1 - 3.2e-103 345.5 0.1 3.8e-103 345.2 0.1 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.19 AFI85083.1 - 0.00013 20.9 0.0 0.00029 19.8 0.0 1.5 1 1 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 AFI85083.1 - 0.0095 15.0 0.1 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF354) Peripla_BP_6 PF13458.6 AFI85083.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein Glyco_tran_28_C PF04101.16 AFI85083.1 - 0.11 12.4 0.2 12 5.8 0.2 2.6 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DHBP_synthase PF00926.19 AFI85084.1 - 3.9e-84 281.0 0.1 1.5e-83 279.1 0.2 1.8 2 0 0 2 2 2 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AFI85084.1 - 1.5e-41 141.7 0.0 3.2e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 GTP cyclohydrolase II NapD PF03927.13 AFI85084.1 - 0.29 11.2 0.7 3.1 7.9 0.1 2.5 2 0 0 2 2 2 0 NapD protein Lum_binding PF00677.17 AFI85085.1 - 9.2e-49 163.4 0.2 3.4e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain RibD_C PF01872.17 AFI85086.1 - 1.1e-53 182.1 0.1 1.4e-53 181.7 0.1 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AFI85086.1 - 2e-23 82.2 0.0 3.4e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AFI85086.1 - 6.8e-13 48.6 0.1 1.4e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 MafB19-like deaminase Inv-AAD PF18785.1 AFI85086.1 - 0.00011 22.0 0.1 0.0007 19.5 0.1 2.1 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase ATP-cone PF03477.16 AFI85087.1 - 1.9e-14 54.0 0.1 2.7e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 ATP cone domain Lar_restr_allev PF14354.6 AFI85087.1 - 0.0042 17.4 0.1 0.0073 16.7 0.1 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 AFI85087.1 - 0.0083 16.1 1.0 0.018 15.0 1.0 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AFI85087.1 - 0.018 14.6 0.7 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3268 PF11672.8 AFI85087.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 2 0 0 2 2 2 0 zinc-finger-containing domain Elf1 PF05129.13 AFI85087.1 - 0.06 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.6 AFI85087.1 - 0.07 13.1 0.7 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 AFI85087.1 - 0.73 10.8 2.3 10 7.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SHMT PF00464.19 AFI85088.1 - 5.8e-182 604.7 0.2 6.8e-182 604.5 0.2 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AFI85088.1 - 9.8e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AFI85088.1 - 0.00011 21.6 0.1 0.00018 20.9 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 AFI85088.1 - 0.0002 20.2 0.0 0.00091 18.1 0.0 1.9 1 1 1 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 AFI85088.1 - 0.0061 15.9 0.1 0.0077 15.6 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AFI85088.1 - 0.0066 15.0 0.1 0.0092 14.5 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NAD_binding_2 PF03446.15 AFI85089.1 - 3.3e-33 115.1 0.0 4.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AFI85089.1 - 2.5e-13 50.4 0.0 3.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AFI85089.1 - 2.3e-11 44.1 0.2 4.1e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AFI85089.1 - 1.7e-06 28.1 0.1 2.9e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 AFI85089.1 - 0.0001 21.7 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AFI85089.1 - 0.00074 19.1 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 AFI85089.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AFI85089.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 AFI85089.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 AFI85089.1 - 0.016 15.4 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_C PF03720.15 AFI85089.1 - 0.034 14.5 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DpaA_N PF16924.5 AFI85089.1 - 0.12 12.4 0.1 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Epimerase PF01370.21 AFI85089.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Adenylsucc_synt PF00709.21 AFI85090.1 - 3e-172 573.3 0.0 3.4e-172 573.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Dor1 PF04124.12 AFI85090.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family tRNA-synt_His PF13393.6 AFI85091.1 - 1.1e-111 373.1 1.0 1.3e-111 372.8 1.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase DUF2065 PF09838.9 AFI85092.1 - 6.7e-18 64.5 2.2 7.2e-18 64.4 2.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2065) Band_7 PF01145.25 AFI85093.1 - 2.4e-28 99.3 0.2 3.3e-28 98.9 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Phage_capsid PF05065.13 AFI85093.1 - 0.061 12.6 0.1 0.082 12.2 0.1 1.1 1 0 0 1 1 1 0 Phage capsid family PsbT PF01405.17 AFI85093.1 - 0.12 12.2 5.9 0.24 11.2 5.9 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein DUF3113 PF11310.8 AFI85093.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Band_7 PF01145.25 AFI85094.1 - 1.5e-28 100.0 1.1 1.5e-28 100.0 1.1 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family HflK_N PF12221.8 AFI85094.1 - 1.2e-16 60.4 7.0 1.2e-16 60.4 7.0 2.0 2 0 0 2 2 2 1 Bacterial membrane protein N terminal Band_7_1 PF13421.6 AFI85094.1 - 0.0057 16.4 0.1 0.0092 15.7 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family GTP-bdg_M PF16360.5 AFI85095.1 - 1.8e-29 102.2 9.6 3.9e-29 101.1 9.6 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 AFI85095.1 - 3.7e-29 101.2 0.0 8.1e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AFI85095.1 - 3.6e-20 72.2 0.0 1.7e-19 70.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AFI85095.1 - 6.7e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AFI85095.1 - 0.00047 20.1 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 AFI85095.1 - 0.0016 18.0 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 AFI85095.1 - 0.0053 16.4 0.5 0.22 11.1 0.1 2.5 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 AFI85095.1 - 0.0076 15.7 0.6 0.083 12.3 0.6 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 AFI85095.1 - 0.016 15.4 0.1 0.32 11.2 0.0 2.8 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MnmE_helical PF12631.7 AFI85095.1 - 0.018 15.2 0.1 0.045 13.9 0.1 1.6 2 0 0 2 2 2 0 MnmE helical domain Ras PF00071.22 AFI85095.1 - 0.097 12.3 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Ras family SRPRB PF09439.10 AFI85095.1 - 0.099 12.1 0.1 0.24 10.8 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 AFI85095.1 - 0.12 12.9 0.0 2.1 8.8 0.0 2.5 1 1 0 2 2 2 0 ABC transporter Hfq PF17209.3 AFI85096.1 - 1.5e-30 104.6 0.6 1.7e-30 104.4 0.6 1.0 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 AFI85096.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.5 1 1 0 1 1 1 1 LSM domain IPPT PF01715.17 AFI85097.1 - 8.5e-83 277.6 0.5 1e-82 277.3 0.5 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AFI85097.1 - 2e-08 33.9 0.0 0.00032 20.2 0.0 2.5 2 1 0 2 2 2 2 Isopentenyl transferase AAA_33 PF13671.6 AFI85097.1 - 0.00033 20.8 0.0 0.0029 17.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AFI85097.1 - 0.076 12.7 0.1 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 AFI85097.1 - 0.1 12.3 0.0 0.37 10.5 0.0 2.0 3 0 0 3 3 3 0 Cytidylate kinase AAA PF00004.29 AFI85097.1 - 0.13 12.7 0.0 0.7 10.3 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rho_RNA_bind PF07497.12 AFI85098.1 - 1e-31 108.6 0.0 3.1e-31 107.1 0.0 1.8 2 0 0 2 2 2 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AFI85098.1 - 1.2e-24 87.2 0.2 1.7e-24 86.7 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AFI85098.1 - 8.7e-13 48.0 3.0 1.9e-12 46.9 3.0 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NACHT PF05729.12 AFI85098.1 - 8.3e-05 22.6 0.0 0.00022 21.2 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 AFI85098.1 - 0.00076 19.9 0.0 0.0016 18.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) OB_RNB PF08206.11 AFI85098.1 - 0.0011 18.7 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_25 PF13481.6 AFI85098.1 - 0.0012 18.5 0.1 0.0041 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI85098.1 - 0.0036 17.6 0.1 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mor PF08765.11 AFI85098.1 - 0.071 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Mor transcription activator family Slp PF03843.13 AFI85099.1 - 8.6e-49 164.8 0.0 1e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein Slp family Ribosomal_L17 PF01196.19 AFI85101.1 - 2.5e-32 111.6 0.0 2.8e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_A_CTD PF03118.15 AFI85102.1 - 1.2e-24 85.8 0.0 2.2e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 AFI85102.1 - 1.7e-23 81.8 0.0 3.5e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 AFI85102.1 - 4.4e-19 68.9 0.0 1.1e-18 67.6 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 AFI85102.1 - 0.0029 17.4 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S4 PF00163.19 AFI85103.1 - 1.7e-29 102.5 5.1 2.4e-29 102.1 3.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AFI85103.1 - 2.8e-18 65.4 0.2 5.3e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AFI85103.1 - 0.0034 17.2 0.3 0.0064 16.3 0.3 1.4 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 AFI85103.1 - 0.025 14.4 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain ThiS PF02597.20 AFI85103.1 - 0.083 13.5 0.0 0.2 12.3 0.0 1.7 1 1 0 1 1 1 0 ThiS family Ribosomal_S11 PF00411.19 AFI85104.1 - 7.3e-51 171.2 0.3 8.6e-51 171.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S13 PF00416.22 AFI85105.1 - 1.3e-35 122.6 5.9 6.5e-34 117.1 5.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AFI85105.1 - 0.006 15.4 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SecY PF00344.20 AFI85106.1 - 3.2e-116 387.9 21.5 4.1e-116 387.5 21.5 1.1 1 0 0 1 1 1 1 SecY translocase Ribosomal_L27A PF00828.19 AFI85107.1 - 2.3e-31 109.1 1.3 3e-31 108.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L30 PF00327.20 AFI85108.1 - 5.2e-16 58.3 0.1 6e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 AFI85109.1 - 2.3e-29 100.6 0.6 4.2e-29 99.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AFI85109.1 - 1.4e-26 92.3 5.2 2.2e-26 91.6 5.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L18p PF00861.22 AFI85110.1 - 4.4e-40 136.7 3.4 4.9e-40 136.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF3263 PF11662.8 AFI85110.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) Ribosomal_L6 PF00347.23 AFI85111.1 - 6e-41 139.0 2.5 1.2e-20 73.9 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 KORA PF16509.5 AFI85111.1 - 0.079 13.3 0.3 13 6.2 0.1 2.2 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor Ribosomal_S8 PF00410.19 AFI85112.1 - 3.8e-47 159.4 0.1 4.2e-47 159.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 AFI85113.1 - 3.3e-25 87.6 0.3 6.6e-25 86.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L5_C PF00673.21 AFI85114.1 - 2.7e-41 139.6 0.0 4.9e-41 138.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AFI85114.1 - 8.7e-28 96.4 0.8 1.6e-27 95.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 DHOR PF06537.11 AFI85114.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase ribosomal_L24 PF17136.4 AFI85115.1 - 3.4e-24 85.0 0.0 5.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AFI85115.1 - 0.013 15.4 4.7 0.013 15.4 4.7 2.4 3 0 0 3 3 3 0 KOW motif DUF3215 PF11503.8 AFI85115.1 - 0.054 13.4 0.2 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) Ribosomal_L14 PF00238.19 AFI85116.1 - 2.1e-19 69.8 0.5 2.7e-19 69.4 0.5 1.2 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e PIG-H PF10181.9 AFI85116.1 - 0.062 13.2 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component Ribosomal_S17 PF00366.20 AFI85117.1 - 1.6e-32 111.4 3.0 1.9e-32 111.2 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L29 PF00831.23 AFI85118.1 - 2.3e-24 85.1 4.8 2.5e-24 85.0 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 AFI85118.1 - 0.0003 20.8 0.7 0.00044 20.3 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF3656 PF12392.8 AFI85118.1 - 0.045 14.4 0.3 0.051 14.2 0.3 1.1 1 0 0 1 1 1 0 Collagenase Ribosomal_L16 PF00252.18 AFI85119.1 - 1.3e-49 167.6 1.2 1.4e-49 167.4 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.20 AFI85120.1 - 1.1e-40 138.0 1.9 1.1e-40 138.0 1.9 1.8 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AFI85120.1 - 9.9e-19 66.9 2.9 9.9e-19 66.9 2.9 1.9 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 AFI85120.1 - 0.00063 19.6 0.1 0.0015 18.3 0.1 1.7 2 0 0 2 2 2 1 KH domain PG_binding_4 PF12229.8 AFI85120.1 - 0.05 13.9 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Ribosomal_L22 PF00237.19 AFI85121.1 - 1.8e-34 118.1 0.1 2e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 AFI85122.1 - 2.4e-22 78.6 0.3 2.6e-22 78.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 AFI85123.1 - 2.3e-53 179.7 3.0 7.3e-53 178.1 3.3 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AFI85123.1 - 3.1e-34 116.8 2.7 1.5e-33 114.5 1.4 2.5 2 1 1 3 3 3 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 AFI85124.1 - 4.8e-31 107.0 1.0 5.4e-31 106.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 P16-Arc PF04699.14 AFI85124.1 - 0.0082 16.7 0.4 0.009 16.5 0.4 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) BCL_N PF04714.13 AFI85124.1 - 0.13 12.3 1.1 0.99 9.5 0.1 2.4 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Ribosomal_L4 PF00573.22 AFI85125.1 - 6.4e-59 198.9 0.7 7.2e-59 198.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 AFI85126.1 - 8.2e-20 71.1 6.6 1.9e-19 69.9 3.6 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 AFI85127.1 - 4.3e-36 123.1 0.2 4.8e-36 122.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 AFI85127.1 - 0.062 14.1 0.0 0.088 13.6 0.0 1.5 1 1 0 1 1 1 0 Primosomal protein N C-terminal domain GTP_EFTU PF00009.27 AFI85128.1 - 2.1e-58 197.1 0.0 2.8e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AFI85128.1 - 5.8e-35 120.0 0.0 1.5e-34 118.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AFI85128.1 - 2.5e-18 66.2 5.5 5.8e-18 65.1 5.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AFI85128.1 - 6.6e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 AFI85128.1 - 0.082 12.5 0.3 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 AFI85129.1 - 4.9e-63 212.2 0.0 7.4e-63 211.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AFI85129.1 - 2e-47 159.9 0.1 4.8e-47 158.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AFI85129.1 - 6.3e-34 115.9 0.0 1.3e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AFI85129.1 - 3.9e-31 106.9 0.0 1.4e-30 105.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AFI85129.1 - 5.4e-18 65.2 0.1 1.4e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AFI85129.1 - 2.3e-06 27.4 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ribosomal_S7 PF00177.21 AFI85130.1 - 6.6e-64 214.1 3.7 7.3e-64 213.9 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 AFI85131.1 - 1.2e-42 144.1 1.0 1.5e-42 143.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 AFI85131.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S12 RNA_pol_Rpb1_1 PF04997.12 AFI85132.1 - 5.3e-85 285.5 0.0 8e-85 284.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AFI85132.1 - 1.9e-77 260.3 0.1 3e-77 259.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AFI85132.1 - 1.8e-37 129.1 0.0 2.4e-27 96.2 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AFI85132.1 - 3.8e-27 95.2 0.0 8e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AFI85132.1 - 4.6e-19 68.3 0.4 9.9e-19 67.3 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Apocytochr_F_C PF01333.19 AFI85132.1 - 4.9e-05 23.4 0.0 0.2 11.7 0.0 3.4 3 0 0 3 3 3 2 Apocytochrome F, C-terminal Biotin_lipoyl_2 PF13533.6 AFI85132.1 - 0.00027 20.7 0.1 0.088 12.7 0.0 3.0 3 0 0 3 3 3 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 AFI85132.1 - 0.14 12.4 0.1 12 6.2 0.0 3.5 4 0 0 4 4 4 0 Peptidase family M23 RNA_pol_Rpb2_6 PF00562.28 AFI85133.1 - 2e-159 530.9 0.2 4.1e-158 526.5 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AFI85133.1 - 1.8e-44 151.7 0.0 5.7e-44 150.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 AFI85133.1 - 5e-31 106.7 0.0 9.8e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 AFI85133.1 - 5.9e-27 94.5 0.0 1.3e-16 60.8 0.0 3.0 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 AFI85133.1 - 2.9e-26 91.7 0.0 7.3e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 AFI85133.1 - 7.3e-22 77.4 0.2 5.1e-21 74.7 0.1 2.7 3 0 0 3 3 3 1 RNA polymerase beta subunit external 1 domain Ribosomal_L12 PF00542.19 AFI85134.1 - 2.8e-29 101.3 4.9 2.8e-29 101.3 4.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AFI85134.1 - 1.3e-19 69.6 12.4 1.3e-19 69.6 12.4 2.7 3 0 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 AFI85134.1 - 0.0011 19.5 8.2 0.0011 19.5 8.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MgtE_N PF03448.17 AFI85134.1 - 0.058 14.0 1.1 0.71 10.5 0.2 2.4 2 1 0 2 2 2 0 MgtE intracellular N domain MCR_alpha PF02249.17 AFI85134.1 - 0.15 12.5 0.4 0.22 12.0 0.4 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Ribosomal_L10 PF00466.20 AFI85135.1 - 4e-23 81.4 0.0 5.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L1 PF00687.21 AFI85136.1 - 1.6e-50 171.7 0.0 2e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11_N PF03946.14 AFI85137.1 - 2.2e-31 107.5 0.5 3.6e-31 106.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AFI85137.1 - 1.7e-26 92.5 0.2 2.7e-26 91.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NusG PF02357.19 AFI85138.1 - 1.4e-27 96.1 0.0 2.3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 AFI85138.1 - 1.8e-08 34.0 0.7 3.7e-08 33.1 0.7 1.5 1 0 0 1 1 1 1 KOW motif SecE PF00584.20 AFI85139.1 - 1.2e-19 69.9 2.6 1.2e-19 69.9 2.6 2.5 3 0 0 3 3 3 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4131 PF13567.6 AFI85139.1 - 0.19 11.4 7.4 0.18 11.5 6.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ceramidase PF05875.12 AFI85139.1 - 0.28 10.6 6.7 0.35 10.2 6.7 1.1 1 0 0 1 1 1 0 Ceramidase PRA1 PF03208.19 AFI85139.1 - 6.7 6.3 12.5 1.6e+02 1.9 12.5 2.0 1 1 0 1 1 1 0 PRA1 family protein GTP_EFTU PF00009.27 AFI85140.1 - 2.1e-58 197.1 0.0 2.8e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AFI85140.1 - 5.8e-35 120.0 0.0 1.5e-34 118.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AFI85140.1 - 2.5e-18 66.2 5.5 5.8e-18 65.1 5.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AFI85140.1 - 6.6e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 AFI85140.1 - 0.082 12.5 0.3 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Proteasome PF00227.26 AFI85141.1 - 2.1e-21 76.3 0.2 4.9e-21 75.1 0.2 1.5 1 1 0 1 1 1 1 Proteasome subunit PspC PF04024.12 AFI85141.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 PspC domain AAA_2 PF07724.14 AFI85142.1 - 2.1e-48 164.7 0.5 1e-39 136.4 0.3 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AFI85142.1 - 2.2e-14 54.0 0.1 1.6e-06 28.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFI85142.1 - 6e-08 32.8 0.1 1.2e-05 25.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AFI85142.1 - 1.7e-06 27.9 1.3 0.019 14.7 0.0 3.5 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AFI85142.1 - 2.1e-06 28.1 2.6 0.00025 21.4 0.0 3.1 2 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 AFI85142.1 - 1.2e-05 24.8 0.2 0.0013 18.1 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 AFI85142.1 - 1.5e-05 24.2 0.1 0.00043 19.4 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 AFI85142.1 - 2.8e-05 24.5 2.4 0.00017 22.0 0.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain ClpB_D2-small PF10431.9 AFI85142.1 - 4.1e-05 23.6 2.4 5.9e-05 23.0 0.1 2.6 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 AFI85142.1 - 0.00036 20.3 0.1 0.029 14.1 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 AFI85142.1 - 0.0012 18.1 1.1 0.0067 15.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 AFI85142.1 - 0.0031 18.1 0.1 0.013 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AFI85142.1 - 0.0085 15.5 0.0 0.032 13.6 0.0 2.0 1 1 0 1 1 1 1 Bacterial TniB protein AAA_33 PF13671.6 AFI85142.1 - 0.0087 16.2 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI85142.1 - 0.01 15.0 0.4 0.031 13.3 0.0 2.0 2 1 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 AFI85142.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AFI85142.1 - 0.022 14.7 0.0 0.072 13.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 AFI85142.1 - 0.03 13.6 0.0 0.079 12.2 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 AFI85142.1 - 0.039 14.2 0.8 0.14 12.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 AFI85142.1 - 0.045 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 AFI85142.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 AFI85142.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Torsin TsaE PF02367.17 AFI85142.1 - 0.069 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 AFI85142.1 - 0.079 13.0 1.5 0.87 9.6 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 AFI85142.1 - 0.082 12.8 0.2 2 8.3 0.0 2.8 3 0 0 3 3 3 0 NACHT domain DEAD PF00270.29 AFI85142.1 - 0.083 12.7 1.0 0.66 9.7 1.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase ATP-synt_G PF04718.15 AFI85142.1 - 0.094 13.5 0.1 0.24 12.2 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit AAA_19 PF13245.6 AFI85142.1 - 9.1 6.6 7.9 8.6 6.7 4.1 2.7 2 1 0 2 2 2 0 AAA domain DUF971 PF06155.12 AFI85143.1 - 8e-27 93.7 0.0 9.6e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Ubie_methyltran PF01209.18 AFI85144.1 - 1.4e-98 328.9 0.0 1.7e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AFI85144.1 - 6.4e-24 84.5 0.0 1.3e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI85144.1 - 2.4e-21 76.2 0.0 4.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI85144.1 - 3.1e-20 72.5 0.0 4.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI85144.1 - 1.3e-17 64.1 0.0 1.9e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85144.1 - 6.7e-12 46.0 0.0 1.1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AFI85144.1 - 3.2e-08 33.6 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AFI85144.1 - 1.7e-05 24.0 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 AFI85144.1 - 0.00017 21.2 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 AFI85144.1 - 0.00084 19.0 0.1 0.0018 17.9 0.1 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 AFI85144.1 - 0.0053 16.5 0.0 0.043 13.5 0.0 2.1 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 AFI85144.1 - 0.018 14.9 0.0 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_18 PF12847.7 AFI85144.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AFI85144.1 - 0.092 12.4 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F SCP2 PF02036.17 AFI85145.1 - 2.2e-07 31.3 0.6 3.8e-07 30.5 0.6 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family BLOC1_2 PF10046.9 AFI85145.1 - 0.019 15.3 0.9 0.51 10.7 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 P63C PF10546.9 AFI85145.1 - 0.091 13.4 1.3 0.96 10.1 2.0 2.2 2 1 0 2 2 2 0 P63C domain ABC1 PF03109.16 AFI85146.1 - 2.2e-32 111.7 0.0 6.9e-32 110.1 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 AFI85146.1 - 0.02 14.8 6.1 1.2 9.1 3.8 3.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 AFI85146.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain FTHFS PF01268.19 AFI85147.1 - 6.8e-260 863.0 0.8 7.6e-260 862.8 0.8 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Transketolase_C PF02780.20 AFI85147.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain FH2 PF02181.23 AFI85147.1 - 0.098 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain CbiA PF01656.23 AFI85147.1 - 0.12 12.5 0.4 0.54 10.3 0.2 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Flavoprotein PF02441.19 AFI85148.1 - 1.6e-26 92.9 0.0 2.1e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Mur_ligase_M PF08245.12 AFI85149.1 - 5.3e-25 88.5 0.0 9e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AFI85149.1 - 2.6e-19 69.3 0.0 2.3e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AFI85149.1 - 5.1e-11 42.7 0.0 1.5e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain FA_desaturase PF00487.24 AFI85150.1 - 0.27 11.0 5.7 0.32 10.8 5.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF2070 PF09843.9 AFI85150.1 - 0.4 8.9 14.3 0.48 8.7 14.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Yip1 PF04893.17 AFI85150.1 - 1.6 8.4 16.9 2.7 7.7 16.8 1.4 1 1 0 1 1 1 0 Yip1 domain Lactonase PF10282.9 AFI85151.1 - 3.5e-17 62.7 0.1 6.6e-09 35.5 0.0 3.5 1 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AFI85151.1 - 1.1e-10 40.6 3.0 0.18 10.3 0.0 3.0 1 1 0 1 1 1 1 Cytochrome D1 heme domain Arylesterase PF01731.20 AFI85151.1 - 1.3e-07 31.7 0.7 0.41 10.9 0.0 4.3 4 0 0 4 4 4 2 Arylesterase ANAPC4_WD40 PF12894.7 AFI85151.1 - 3e-07 30.7 0.5 0.33 11.3 0.0 5.2 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 AFI85151.1 - 1.2e-06 28.3 0.4 0.13 11.9 0.0 3.4 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Glu_cyclase_2 PF05096.12 AFI85151.1 - 8e-05 22.2 0.0 0.023 14.1 0.0 2.5 1 1 2 3 3 3 1 Glutamine cyclotransferase DUF1513 PF07433.11 AFI85151.1 - 0.012 14.8 0.1 4.6 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.12 AFI85151.1 - 0.012 15.5 0.1 3.5 7.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat NHL PF01436.21 AFI85151.1 - 0.015 15.3 10.5 27 5.0 0.0 6.6 7 0 0 7 7 7 0 NHL repeat PQQ_3 PF13570.6 AFI85151.1 - 0.017 15.6 2.9 13 6.4 0.1 4.3 6 0 0 6 6 6 0 PQQ-like domain DKNYY PF13644.6 AFI85151.1 - 0.031 15.1 0.1 0.52 11.1 0.0 2.2 2 0 0 2 2 2 0 DKNYY family WD40 PF00400.32 AFI85151.1 - 0.059 14.3 0.0 6.9 7.7 0.0 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat SecD_SecF PF02355.16 AFI85154.1 - 2.6e-69 232.4 15.1 2.6e-69 232.4 15.1 1.6 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 AFI85154.1 - 8.6e-09 34.6 0.1 2.1e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif tRNA-synt_1e PF01406.19 AFI85154.1 - 0.03 13.7 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SpoIIIAH PF12685.7 AFI85154.1 - 1.5 8.6 3.4 0.75 9.6 0.2 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein SecD-TM1 PF13721.6 AFI85155.1 - 1.9e-35 121.4 0.3 1.9e-35 121.4 0.3 4.0 4 0 0 4 4 4 1 SecD export protein N-terminal TM region SecD_SecF PF02355.16 AFI85155.1 - 1.9e-19 69.8 12.1 4.4e-19 68.6 12.1 1.5 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 AFI85155.1 - 1.2e-10 40.9 15.5 2.5e-10 39.8 15.5 1.5 1 0 0 1 1 1 1 MMPL family Sec_GG PF07549.14 AFI85155.1 - 8.4e-08 31.5 0.0 2.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 SecD/SecF GG Motif RimM PF01782.18 AFI85155.1 - 0.03 14.6 0.7 1.6 9.0 0.1 3.2 3 0 0 3 3 3 0 RimM N-terminal domain YajC PF02699.15 AFI85156.1 - 8.4e-27 92.9 0.1 1.1e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit TGT PF01702.18 AFI85157.1 - 3.7e-153 509.8 0.0 4.4e-153 509.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase OMPdecase PF00215.24 AFI85158.1 - 1.4e-48 165.5 0.1 1.5e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MCPsignal PF00015.21 AFI85159.1 - 6.8e-44 149.7 41.2 9.7e-44 149.2 25.9 2.6 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain T3SSipB PF16535.5 AFI85159.1 - 0.00033 21.2 20.3 0.0038 17.7 2.7 3.3 2 1 1 3 3 3 2 Type III cell invasion protein SipB PHA_synth_III_E PF09712.10 AFI85159.1 - 0.0024 17.0 7.5 0.033 13.3 0.4 2.3 2 0 0 2 2 2 2 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) EzrA PF06160.12 AFI85159.1 - 0.0072 14.6 11.5 0.019 13.1 0.9 3.0 1 1 2 3 3 3 1 Septation ring formation regulator, EzrA HAMP PF00672.25 AFI85159.1 - 0.012 15.9 6.9 1.2 9.6 0.0 4.6 6 1 0 6 6 4 0 HAMP domain Syntaxin_2 PF14523.6 AFI85159.1 - 0.029 14.8 13.5 0.24 11.8 0.5 3.9 2 1 2 4 4 4 0 Syntaxin-like protein DUF948 PF06103.11 AFI85159.1 - 0.037 14.3 31.1 1.8 8.9 1.3 4.7 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Xpo1 PF08389.12 AFI85159.1 - 0.042 13.9 4.2 0.12 12.5 0.5 2.4 2 0 0 2 2 2 0 Exportin 1-like protein CHDCT2 PF08074.11 AFI85159.1 - 0.05 13.8 10.2 0.11 12.7 1.5 2.5 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Pex19 PF04614.12 AFI85159.1 - 0.05 13.4 16.8 0.32 10.7 4.3 2.1 2 0 0 2 2 2 0 Pex19 protein family TACC_C PF05010.14 AFI85159.1 - 0.055 13.3 7.3 0.74 9.6 1.8 2.5 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Fib_alpha PF08702.10 AFI85159.1 - 0.17 12.0 17.4 0.23 11.6 4.9 3.4 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF2353 PF09789.9 AFI85159.1 - 0.19 11.1 9.8 0.31 10.3 6.4 2.3 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Vps53_N PF04100.12 AFI85159.1 - 0.29 10.1 20.1 0.47 9.4 5.4 2.9 1 1 2 3 3 3 0 Vps53-like, N-terminal DUF1664 PF07889.12 AFI85159.1 - 0.39 10.8 20.8 0.85 9.7 2.1 4.1 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 AFI85159.1 - 0.41 10.3 32.8 0.44 10.2 9.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) GIDA_assoc PF13932.6 AFI85159.1 - 0.65 10.1 9.4 4.2 7.5 0.8 2.2 2 0 0 2 2 2 0 GidA associated domain COG5 PF10392.9 AFI85159.1 - 0.75 10.0 7.6 7.5 6.7 0.0 3.8 2 2 1 3 3 3 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.22 AFI85159.1 - 0.85 9.9 17.8 0.69 10.2 2.8 3.2 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_I PF06008.14 AFI85159.1 - 0.91 9.2 22.9 0.095 12.4 7.5 2.5 2 1 0 2 2 2 0 Laminin Domain I DUF4200 PF13863.6 AFI85159.1 - 1.1 9.7 10.1 10 6.6 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 AFI85159.1 - 1.4 8.1 9.0 2.3 7.4 1.0 2.3 2 0 0 2 2 2 0 TMPIT-like protein BLOC1_2 PF10046.9 AFI85159.1 - 1.6 9.1 16.7 1.1 9.6 1.2 3.4 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMP_2 PF06791.13 AFI85159.1 - 2.3 7.9 32.3 9.7 5.8 9.4 3.0 1 1 1 2 2 2 0 Prophage tail length tape measure protein Plk4_PB2 PF18409.1 AFI85159.1 - 3.5 8.4 11.7 2.6 8.8 1.1 3.7 2 2 2 4 4 4 0 Polo-like Kinase 4 Polo Box 2 Vps54_N PF10475.9 AFI85159.1 - 3.7 6.8 9.3 0.91 8.7 4.5 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex TolA_bind_tri PF16331.5 AFI85159.1 - 3.8 7.7 7.4 9.4 6.4 0.1 4.0 3 1 1 4 4 4 0 TolA binding protein trimerisation CK2S PF15011.6 AFI85159.1 - 3.8 7.4 8.9 4 7.3 1.4 3.5 1 1 1 3 3 3 0 Casein Kinase 2 substrate DUF724 PF05266.14 AFI85159.1 - 5.2 6.9 14.0 3.3 7.5 4.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) MAT1 PF06391.13 AFI85159.1 - 5.3 6.8 9.7 6.5 6.5 1.2 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Laminin_II PF06009.12 AFI85159.1 - 6.4 6.8 26.7 2.5 8.1 2.2 3.6 2 2 1 3 3 3 0 Laminin Domain II Atg14 PF10186.9 AFI85159.1 - 6.7 5.7 13.9 16 4.5 1.4 3.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2721 PF11026.8 AFI85159.1 - 7.4 6.5 6.6 54 3.7 3.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Mcm10 PF09332.11 AFI85159.1 - 7.6 5.8 9.9 12 5.3 9.9 1.3 1 0 0 1 1 1 0 Mcm10 replication factor DUF2385 PF09539.10 AFI85159.1 - 7.9 7.1 6.8 37 4.9 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) DUF2203 PF09969.9 AFI85159.1 - 8.4 7.1 17.0 5.5 7.7 3.7 3.5 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ERM PF00769.19 AFI85159.1 - 9.9 5.9 21.7 9.9 5.9 8.4 2.3 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Flg_hook PF02120.16 AFI85160.1 - 2e-26 91.7 1.1 2e-26 91.7 1.1 2.1 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK Globin PF00042.22 AFI85161.1 - 3.2e-11 43.7 0.1 1.5e-10 41.6 0.1 2.3 2 0 0 2 2 2 1 Globin MCPsignal PF00015.21 AFI85161.1 - 4.7e-08 33.0 1.0 1.2e-07 31.7 1.0 1.7 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS PF00989.25 AFI85161.1 - 0.0035 17.3 0.9 0.012 15.6 0.0 2.3 3 1 1 4 4 4 1 PAS fold Protoglobin PF11563.8 AFI85161.1 - 0.0041 17.0 0.5 0.0041 17.0 0.5 2.6 4 0 0 4 4 4 1 Protoglobin AP_endonuc_2 PF01261.24 AFI85161.1 - 0.18 11.2 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel FlaC_arch PF05377.11 AFI85161.1 - 3.9 7.9 5.6 5.5 7.5 0.0 3.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Carbpep_Y_N PF05388.11 AFI85161.1 - 7.8 7.1 8.7 30 5.2 4.3 2.7 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide AAA_31 PF13614.6 AFI85162.1 - 1.1e-27 97.1 0.3 1.4e-27 96.8 0.3 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AFI85162.1 - 7.6e-15 55.1 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AFI85162.1 - 3.9e-07 29.8 0.1 6e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 AFI85162.1 - 5.6e-06 26.0 0.5 1.2e-05 24.9 0.4 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AFI85162.1 - 1.9e-05 24.0 0.0 3.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AFI85162.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 AFI85162.1 - 0.00031 20.1 0.1 0.00052 19.4 0.1 1.3 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 AFI85162.1 - 0.018 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AFI85162.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 AFI85162.1 - 0.041 13.5 0.1 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CTP_synth_N PF06418.14 AFI85162.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 CTP synthase N-terminus CheW PF01584.19 AFI85163.1 - 5.1e-15 55.3 0.2 6.6e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AFI85164.1 - 4.9e-15 55.4 0.3 8.3e-15 54.6 0.3 1.4 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AFI85164.1 - 1.8e-14 54.2 0.0 3.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 AFI85164.1 - 1.2e-11 44.7 0.9 1.2e-11 44.7 0.9 2.3 2 1 0 2 2 2 1 Hpt domain Response_reg PF00072.24 AFI85165.1 - 9.9e-25 86.9 0.0 1.1e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 AFI85165.1 - 6.9e-05 23.2 0.0 9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ STAS_2 PF13466.6 AFI85166.1 - 2.6e-10 40.5 0.0 2.8e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AFI85166.1 - 1.6e-05 24.5 0.1 1.8e-05 24.3 0.1 1.0 1 0 0 1 1 1 1 STAS domain FliJ PF02050.16 AFI85167.1 - 5e-21 75.2 27.7 5.7e-21 75.0 27.7 1.0 1 0 0 1 1 1 1 Flagellar FliJ protein SicP-binding PF09119.10 AFI85167.1 - 0.098 12.6 3.3 0.11 12.5 1.2 1.9 1 1 1 2 2 2 0 SicP binding ATP-synt_ab PF00006.25 AFI85168.1 - 5.1e-74 248.5 0.0 7.4e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AFI85168.1 - 4.9e-24 84.0 2.4 9.6e-24 83.0 2.4 1.5 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ABC_tran PF00005.27 AFI85168.1 - 0.041 14.4 1.0 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 ABC transporter ATP-synt_ab_N PF02874.23 AFI85168.1 - 0.05 14.1 1.3 0.24 11.9 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, beta-barrel domain FliH PF02108.16 AFI85169.1 - 1.7e-30 105.7 1.1 3.3e-30 104.8 0.6 1.7 2 0 0 2 2 2 1 Flagellar assembly protein FliH Yae1_N PF09811.9 AFI85169.1 - 0.0099 15.6 6.1 0.015 15.0 6.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal HrpE PF06188.12 AFI85169.1 - 0.016 15.1 1.0 0.026 14.4 1.0 1.4 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E FliG_N PF14842.6 AFI85170.1 - 9.9e-47 157.8 1.1 1.1e-32 112.6 0.0 3.1 3 0 0 3 3 3 2 FliG N-terminal domain FliG_C PF01706.16 AFI85170.1 - 1.7e-46 156.9 7.6 2e-40 137.3 4.1 3.1 3 0 0 3 3 3 2 FliG C-terminal domain FliG_M PF14841.6 AFI85170.1 - 2.7e-31 107.6 0.3 3e-24 85.0 0.0 3.7 4 0 0 4 4 4 2 FliG middle domain MgtE_N PF03448.17 AFI85170.1 - 1.4e-06 28.8 8.1 0.65 10.6 0.1 4.0 3 1 0 3 3 3 3 MgtE intracellular N domain DUF937 PF06078.11 AFI85170.1 - 9.1e-05 23.1 3.9 0.00026 21.6 1.1 2.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF937) hnRNP_Q_AcD PF18360.1 AFI85170.1 - 0.067 13.2 0.1 5.5 7.0 0.0 3.4 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain YscJ_FliF PF01514.17 AFI85171.1 - 1.5e-69 233.5 0.6 3e-69 232.6 0.6 1.5 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AFI85171.1 - 2.8e-46 157.6 2.1 5.2e-46 156.7 0.3 2.3 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal XPC-binding PF09280.11 AFI85171.1 - 0.017 14.8 0.0 0.058 13.1 0.0 2.0 1 0 0 1 1 1 0 XPC-binding domain FliE PF02049.18 AFI85172.1 - 1.3e-31 108.6 4.1 1.7e-31 108.2 3.6 1.4 1 1 0 1 1 1 1 Flagellar hook-basal body complex protein FliE Cytochrom_B562 PF07361.11 AFI85172.1 - 0.042 14.5 1.6 0.15 12.8 0.4 1.9 1 1 1 2 2 2 0 Cytochrome b562 Sigma54_activat PF00158.26 AFI85173.1 - 1.7e-67 226.4 0.2 7.1e-67 224.3 0.1 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 AFI85173.1 - 5.4e-26 90.9 0.1 1.2e-25 89.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AFI85173.1 - 9.8e-18 64.6 0.1 3e-16 59.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AFI85173.1 - 2.4e-10 40.0 0.5 6.3e-10 38.7 0.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI85173.1 - 3.7e-07 30.2 0.1 3.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) HTH_28 PF13518.6 AFI85173.1 - 1.1e-06 28.7 1.0 2.3e-06 27.6 0.4 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_30 PF13556.6 AFI85173.1 - 7.3e-06 25.7 0.3 2e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA PF00004.29 AFI85173.1 - 1.7e-05 25.3 0.1 8.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HTH_23 PF13384.6 AFI85173.1 - 2.4e-05 24.0 0.3 6.1e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 Homeodomain-like domain AAA_16 PF13191.6 AFI85173.1 - 0.00034 21.0 4.0 0.002 18.6 2.3 2.6 2 1 0 2 2 1 1 AAA ATPase domain MCM PF00493.23 AFI85173.1 - 0.00042 19.5 0.2 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain HTH_11 PF08279.12 AFI85173.1 - 0.00058 19.7 0.0 0.0029 17.5 0.1 2.2 2 0 0 2 2 1 1 HTH domain AAA_PrkA PF08298.11 AFI85173.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_3 PF07726.11 AFI85173.1 - 0.0029 17.5 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_29 PF13551.6 AFI85173.1 - 0.004 17.1 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 AFI85173.1 - 0.0055 16.2 0.2 0.019 14.5 0.2 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Mg_chelatase PF01078.21 AFI85173.1 - 0.0072 15.7 0.0 0.54 9.6 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma70_r4_2 PF08281.12 AFI85173.1 - 0.0072 16.0 0.2 0.019 14.7 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 DUF2089 PF09862.9 AFI85173.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) AAA_2 PF07724.14 AFI85173.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) FleQ PF06490.11 AFI85173.1 - 0.025 15.0 0.0 0.074 13.4 0.0 1.9 2 0 0 2 2 1 0 Flagellar regulatory protein FleQ HTH_12 PF08461.10 AFI85173.1 - 0.027 14.4 0.2 0.8 9.7 0.3 3.0 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain AAA_7 PF12775.7 AFI85173.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PaaX PF07848.12 AFI85173.1 - 0.08 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 PaaX-like protein HTH_1 PF00126.27 AFI85173.1 - 0.11 12.5 0.4 1 9.4 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Mga PF08280.11 AFI85173.1 - 0.13 12.3 0.8 0.46 10.5 0.0 2.2 3 0 0 3 3 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_50 PF18024.1 AFI85173.1 - 0.15 11.7 0.4 0.4 10.3 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HATPase_c PF02518.26 AFI85174.1 - 6.2e-20 71.8 0.0 1.2e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI85174.1 - 1.7e-10 40.8 0.6 4.8e-10 39.3 0.6 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AFI85174.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI85174.1 - 1.3e-06 28.2 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 AFI85174.1 - 5.2e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AFI85174.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HBM PF16591.5 AFI85174.1 - 0.025 14.0 0.4 0.057 12.8 0.3 1.8 1 1 0 1 1 1 0 Helical bimodular sensor domain PAS_7 PF12860.7 AFI85174.1 - 0.052 13.7 0.3 8.3 6.6 0.0 2.8 2 1 1 3 3 3 0 PAS fold PAS_4 PF08448.10 AFI85174.1 - 0.13 12.5 0.1 11 6.3 0.0 2.4 1 1 1 2 2 2 0 PAS fold Sigma54_activat PF00158.26 AFI85175.1 - 3.3e-73 244.9 0.0 4.7e-73 244.4 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AFI85175.1 - 2.3e-24 86.1 0.0 7.1e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain FleQ PF06490.11 AFI85175.1 - 1.8e-13 50.8 0.0 4.4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ HTH_8 PF02954.19 AFI85175.1 - 5.9e-10 38.8 1.7 1.1e-09 37.9 1.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AFI85175.1 - 8e-08 32.4 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AFI85175.1 - 0.00082 19.8 0.0 0.0021 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain HTH_50 PF18024.1 AFI85175.1 - 0.0012 18.4 0.9 0.0033 17.0 0.9 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Mg_chelatase PF01078.21 AFI85175.1 - 0.002 17.6 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 AFI85175.1 - 0.0035 16.9 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 AFI85175.1 - 0.0057 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AFI85175.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) FliT PF05400.13 AFI85176.1 - 1.8e-15 57.5 0.6 2.3e-15 57.2 0.6 1.1 1 0 0 1 1 1 1 Flagellar protein FliT GIT1_C PF12205.8 AFI85176.1 - 0.019 15.1 1.9 0.023 14.8 1.9 1.1 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term GAIN PF16489.5 AFI85176.1 - 0.048 13.1 1.6 0.058 12.8 1.6 1.4 1 1 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain FliS PF02561.14 AFI85177.1 - 4.1e-35 120.5 0.0 4.7e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FliS DUF4924 PF16271.5 AFI85177.1 - 0.082 12.9 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) FliD_C PF07195.12 AFI85178.1 - 1.5e-37 129.3 5.5 1.5e-37 129.3 5.5 1.9 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 AFI85178.1 - 2.6e-25 88.9 0.7 2.6e-25 88.9 0.7 4.2 4 1 1 5 5 5 1 Flagellar hook-associated protein 2 N-terminus Flagellin_IN PF07196.13 AFI85178.1 - 5.2e-09 36.2 7.1 5.2e-09 36.2 7.1 5.2 6 0 0 6 6 6 1 Flagellin hook IN motif IL12 PF03039.14 AFI85178.1 - 0.058 12.7 0.3 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Interleukin-12 alpha subunit Fmp27_WPPW PF10359.9 AFI85178.1 - 0.083 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nuc_recep-AF1 PF11825.8 AFI85178.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.1 3 0 0 3 3 3 0 Nuclear/hormone receptor activator site AF-1 TBCC_N PF16752.5 AFI85178.1 - 0.18 12.3 0.9 6.2 7.3 0.1 2.8 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain NPV_P10 PF05531.12 AFI85178.1 - 3.7 8.1 8.6 4.9 7.7 0.4 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FlaG PF03646.15 AFI85179.1 - 7e-23 80.7 0.4 8.9e-23 80.4 0.4 1.2 1 0 0 1 1 1 1 FlaG protein DUF327 PF03885.13 AFI85179.1 - 0.012 15.6 1.5 0.016 15.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF327) ImcF-related_N PF14331.6 AFI85179.1 - 0.049 13.0 0.2 0.057 12.8 0.2 1.1 1 0 0 1 1 1 0 ImcF-related N-terminal domain DivIC PF04977.15 AFI85179.1 - 0.052 13.3 1.3 0.13 12.1 1.3 1.7 1 1 0 1 1 1 0 Septum formation initiator MitMem_reg PF13012.6 AFI85179.1 - 0.052 14.0 0.2 0.063 13.7 0.2 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function GrpE PF01025.19 AFI85179.1 - 0.057 13.1 0.2 0.076 12.7 0.2 1.3 1 0 0 1 1 1 0 GrpE Spectrin PF00435.21 AFI85179.1 - 0.068 13.7 0.3 0.092 13.2 0.3 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF2680 PF10925.8 AFI85179.1 - 0.39 10.8 2.6 9.5 6.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Flagellin_N PF00669.20 AFI85180.1 - 2.5e-36 124.8 17.3 2.5e-36 124.8 17.3 2.3 1 1 1 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AFI85180.1 - 8.7e-23 80.5 7.2 8.7e-23 80.5 7.2 3.2 3 1 1 4 4 4 1 Bacterial flagellin C-terminal helical region Snapin_Pallidin PF14712.6 AFI85180.1 - 0.003 18.0 2.3 0.53 10.7 0.2 3.1 3 0 0 3 3 3 1 Snapin/Pallidin DUF1843 PF08898.10 AFI85180.1 - 0.015 15.8 0.2 2.6 8.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SLATT_1 PF18181.1 AFI85180.1 - 0.055 13.4 4.2 0.15 12.0 4.2 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3037 PF11236.8 AFI85180.1 - 0.073 13.5 0.7 0.52 10.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) DUF4200 PF13863.6 AFI85180.1 - 0.082 13.3 0.7 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 AFI85180.1 - 0.27 11.4 1.6 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 Tropomyosin like WXG100 PF06013.12 AFI85180.1 - 3.7 7.9 11.8 5.2 7.4 0.4 4.1 4 1 1 5 5 5 0 Proteins of 100 residues with WXG MafB PF06255.13 AFI85180.1 - 7.6 5.9 10.3 0.82 9.0 3.9 2.0 1 1 0 2 2 2 0 Neisseria toxin MafB Flagellin_N PF00669.20 AFI85181.1 - 5.1e-36 123.8 16.8 5.1e-36 123.8 16.8 3.0 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AFI85181.1 - 1e-23 83.5 4.8 1e-23 83.5 4.8 3.0 3 1 0 3 3 3 1 Bacterial flagellin C-terminal helical region Snapin_Pallidin PF14712.6 AFI85181.1 - 0.0051 17.2 3.1 1.5 9.3 0.1 3.4 3 1 0 3 3 3 1 Snapin/Pallidin Syntaxin_2 PF14523.6 AFI85181.1 - 0.014 15.8 4.1 5.1 7.5 0.2 3.2 3 0 0 3 3 3 0 Syntaxin-like protein DUF3037 PF11236.8 AFI85181.1 - 0.029 14.8 0.8 0.15 12.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) FliS_cochap PF16522.5 AFI85181.1 - 0.056 13.4 2.8 0.66 9.9 0.4 2.6 2 1 0 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 CLZ PF16526.5 AFI85181.1 - 0.1 13.0 0.7 20 5.6 0.0 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 AFI85181.1 - 0.29 11.3 1.3 1.5 9.0 0.1 2.4 3 0 0 3 3 3 0 Tropomyosin like Spc7 PF08317.11 AFI85181.1 - 0.3 9.9 2.2 8.4 5.2 0.2 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein Glycos_transf_2 PF00535.26 AFI85182.1 - 2.2e-47 161.0 0.1 5.3e-21 75.2 0.0 3.5 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AFI85182.1 - 6e-19 68.8 0.0 1.4e-11 44.8 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AFI85182.1 - 8.5e-16 58.2 1.5 2.7e-10 40.2 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 AFI85182.1 - 2.8e-08 33.7 0.2 1.1e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family Glyco_trans_1_2 PF13524.6 AFI85182.1 - 2e-05 24.9 0.0 0.00019 21.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_4 PF13704.6 AFI85182.1 - 3.6e-05 24.2 0.3 0.0088 16.5 0.1 3.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 NTP_transf_3 PF12804.7 AFI85182.1 - 0.00081 19.8 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 MobA-like NTP transferase domain GHL5 PF14872.6 AFI85182.1 - 0.015 13.4 0.6 1.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 Glyco_trans_2_3 PF13632.6 AFI85182.1 - 0.017 15.0 0.1 0.067 13.1 0.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 CmcI PF04989.12 AFI85183.1 - 1.2e-80 270.0 0.0 3e-80 268.7 0.0 1.6 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 AFI85183.1 - 4.3e-07 30.9 0.0 7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 AFI85184.1 - 3.8e-11 43.3 0.0 5.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Pyr_redox_2 PF07992.14 AFI85184.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 AFI85185.1 - 1.8e-18 66.9 0.1 1.9e-17 63.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI85185.1 - 1.9e-13 50.9 0.0 4.7e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI85185.1 - 8.4e-13 48.4 0.0 6.1e-12 45.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI85185.1 - 1.6e-11 44.8 0.0 4.8e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85185.1 - 1.4e-08 35.3 0.2 4.8e-06 27.2 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.17 AFI85185.1 - 0.0055 16.2 0.0 0.065 12.7 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 AFI85185.1 - 0.0061 16.1 0.1 0.028 14.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 AFI85185.1 - 0.0097 16.0 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 AFI85185.1 - 0.013 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 AFI85185.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain U3snoRNP10 PF12397.8 AFI85185.1 - 0.14 12.5 0.3 0.42 11.0 0.3 1.8 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 TF_Zn_Ribbon PF08271.12 AFI85185.1 - 0.15 11.6 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding SPASM PF13186.6 AFI85186.1 - 1.1e-15 57.9 0.5 2.7e-15 56.6 0.5 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Radical_SAM PF04055.21 AFI85186.1 - 7.3e-15 55.7 0.0 1.1e-14 55.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AFI85186.1 - 0.044 13.9 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Methyltransf_21 PF05050.12 AFI85187.1 - 8.7e-09 35.6 0.0 1.9e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.7 AFI85187.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PALP PF00291.25 AFI85187.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glycos_transf_1 PF00534.20 AFI85188.1 - 1.3e-12 47.6 0.0 2.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI85188.1 - 2.6e-10 40.9 0.0 6.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI85188.1 - 3.4e-10 40.2 0.1 7.6e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Radical_SAM PF04055.21 AFI85189.1 - 1.9e-16 60.9 0.0 2.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AFI85189.1 - 3.2e-15 56.4 1.2 2.2e-14 53.7 0.3 2.4 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain DUF1272 PF06906.11 AFI85189.1 - 0.017 15.2 0.2 0.017 15.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Fer4_14 PF13394.6 AFI85189.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Epimerase PF01370.21 AFI85190.1 - 1.3e-24 87.0 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AFI85190.1 - 1.7e-15 57.3 0.1 4.9e-15 55.7 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AFI85190.1 - 6.7e-13 48.9 0.0 3.3e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 AFI85190.1 - 3.3e-06 27.4 0.0 1e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 AFI85190.1 - 2.1e-05 23.7 0.0 0.00014 21.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AFI85190.1 - 2.4e-05 24.0 0.4 5.1e-05 23.0 0.4 1.9 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 AFI85190.1 - 0.00013 21.2 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AFI85190.1 - 0.00034 19.9 0.1 0.00057 19.1 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 AFI85190.1 - 0.001 18.2 0.0 0.014 14.5 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 AFI85190.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 AFI85190.1 - 0.15 12.0 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 KR domain Methyltransf_14 PF08484.11 AFI85191.1 - 2.6e-62 209.4 0.0 3.9e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 AFI85191.1 - 2.3e-24 85.4 0.7 5.1e-24 84.3 0.7 1.6 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 AFI85191.1 - 4.7e-12 46.0 0.1 1.3e-11 44.7 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85191.1 - 0.00014 22.5 0.0 0.00032 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain dTDP_sugar_isom PF00908.17 AFI85192.1 - 8.4e-56 188.3 0.0 9.4e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase GDP_Man_Dehyd PF16363.5 AFI85193.1 - 2.7e-38 132.2 0.0 1e-37 130.3 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AFI85193.1 - 4.2e-33 114.8 0.0 5.4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AFI85193.1 - 2.7e-17 62.9 0.0 3e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AFI85193.1 - 2.2e-11 43.4 0.0 3.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AFI85193.1 - 6.4e-10 38.5 0.0 8.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AFI85193.1 - 1.5e-07 30.9 0.1 4.1e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NTP_transferase PF00483.23 AFI85194.1 - 9.9e-20 71.2 0.0 1.5e-19 70.5 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI85194.1 - 2.4e-08 34.5 0.0 2.5e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AFI85194.1 - 0.056 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Flagellin_N PF00669.20 AFI85195.1 - 1e-31 109.9 11.4 1e-31 109.9 11.4 2.7 3 0 0 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AFI85195.1 - 6.4e-06 26.5 5.0 6.4e-06 26.5 5.0 2.9 3 1 0 3 3 3 1 Bacterial flagellin C-terminal helical region Med10 PF09748.9 AFI85195.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex RebB PF11747.8 AFI85195.1 - 1.1 9.4 6.5 3.1 7.9 1.3 3.2 2 1 1 3 3 3 0 Killing trait Flg_bbr_C PF06429.13 AFI85196.1 - 8.8e-11 41.8 3.8 8.8e-11 41.8 3.8 2.4 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AFI85196.1 - 3.9e-05 23.5 7.9 7.8e-05 22.5 5.8 2.8 2 0 0 2 2 2 1 Flagella basal body rod protein DUF4404 PF14357.6 AFI85196.1 - 0.74 10.5 3.8 0.58 10.8 0.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Glucosaminidase PF01832.20 AFI85197.1 - 2.7e-20 72.7 0.0 5.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rod-binding PF10135.9 AFI85197.1 - 3.1e-15 56.5 1.5 7.8e-15 55.2 1.5 1.7 1 0 0 1 1 1 1 Rod binding protein Clr2_transil PF16761.5 AFI85197.1 - 0.029 15.2 0.2 0.12 13.2 0.0 1.9 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 ICAM_N PF03921.14 AFI85197.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain FlgI PF02119.16 AFI85198.1 - 2e-140 467.6 5.1 2.3e-140 467.4 5.1 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein Cohesin PF00963.18 AFI85198.1 - 1.1 9.6 4.2 0.54 10.5 0.1 2.6 4 0 0 4 4 4 0 Cohesin domain FlgH PF02107.16 AFI85199.1 - 4.5e-58 195.6 1.1 5.3e-58 195.3 1.1 1.1 1 0 0 1 1 1 1 Flagellar L-ring protein Flg_bbr_C PF06429.13 AFI85200.1 - 5e-27 93.8 1.5 1e-25 89.7 0.3 2.7 3 0 0 3 3 3 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AFI85200.1 - 2.8e-14 52.7 0.4 2.8e-14 52.7 0.4 2.0 2 0 0 2 2 2 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AFI85201.1 - 6.1e-21 74.4 2.0 6.1e-21 74.4 2.0 1.8 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AFI85201.1 - 3.7e-05 23.5 7.8 3.7e-05 23.5 7.8 2.0 2 0 0 2 2 2 1 Flagella basal body rod protein IMD PF08397.11 AFI85201.1 - 0.096 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain FlaE PF07559.14 AFI85202.1 - 1.6e-21 77.1 8.1 1.6e-21 77.1 8.1 2.3 3 0 0 3 3 3 1 Flagellar basal body protein FlaE Flg_bbr_C PF06429.13 AFI85202.1 - 9.3e-17 60.9 0.3 9.3e-17 60.9 0.3 2.9 3 0 0 3 3 3 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AFI85202.1 - 3.4e-07 30.1 5.6 3.4e-07 30.1 5.6 2.8 2 0 0 2 2 2 1 Flagella basal body rod protein DUF4827 PF16109.5 AFI85202.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) FlgD PF03963.14 AFI85203.1 - 1.1e-19 70.5 3.5 2e-19 69.7 3.5 1.4 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AFI85203.1 - 6.9e-17 61.1 0.1 1.2e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AFI85203.1 - 1.7e-16 60.2 1.5 2.7e-16 59.5 1.5 1.3 1 0 0 1 1 1 1 FlgD Tudor-like domain CHU_C PF13585.6 AFI85203.1 - 0.00025 21.0 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of CHU protein family DUF2271 PF10029.9 AFI85203.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Flg_bbr_C PF06429.13 AFI85204.1 - 1.5e-10 41.1 4.6 2.7e-10 40.3 4.5 1.8 1 1 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AFI85204.1 - 4.6e-09 36.0 1.4 1.3e-08 34.5 1.4 1.9 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bb_rod PF00460.20 AFI85205.1 - 0.00023 21.0 0.1 0.00023 21.0 0.1 2.2 2 1 0 2 2 2 1 Flagella basal body rod protein GspH PF12019.8 AFI85206.1 - 5.6e-32 110.4 1.3 7.9e-32 109.9 1.3 1.2 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AFI85206.1 - 1.9e-06 27.2 4.4 3.2e-06 26.5 4.4 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif COX2_TM PF02790.15 AFI85206.1 - 0.05 13.7 0.2 0.077 13.1 0.2 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain N_methyl PF07963.12 AFI85207.1 - 8.6e-08 31.4 1.1 1.3e-07 30.8 1.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Phage_holin_T PF11031.8 AFI85207.1 - 0.056 12.9 0.3 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 Bacteriophage T holin DUF3096 PF11295.8 AFI85207.1 - 0.069 12.8 1.1 0.11 12.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) PilW PF16074.5 AFI85208.1 - 5.5e-28 97.5 0.7 9e-28 96.8 0.7 1.4 1 0 0 1 1 1 1 Type IV Pilus-assembly protein W N_methyl PF07963.12 AFI85208.1 - 5.5e-08 32.0 2.8 9.8e-08 31.3 2.8 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PilX PF13681.6 AFI85209.1 - 7.5e-19 67.9 0.6 1.2e-18 67.3 0.6 1.3 1 0 0 1 1 1 1 Type IV pilus assembly protein PilX C-term PilX_N PF14341.6 AFI85209.1 - 6e-14 51.7 0.8 9.6e-14 51.1 0.8 1.4 1 0 0 1 1 1 1 PilX N-terminal Neisseria_PilC PF05567.11 AFI85210.1 - 1.4e-66 225.0 5.2 2.2e-66 224.4 5.2 1.3 1 0 0 1 1 1 1 Neisseria PilC beta-propeller domain PQQ PF01011.21 AFI85210.1 - 9.9e-06 25.2 2.2 0.061 13.3 0.1 4.4 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.6 AFI85210.1 - 0.00062 20.2 2.8 0.0062 17.0 0.1 4.1 4 0 0 4 4 4 1 PQQ-like domain Dockerin_1 PF00404.18 AFI85210.1 - 0.043 14.0 1.7 1.9 8.7 0.1 2.9 2 0 0 2 2 2 0 Dockerin type I domain FliN_N PF16973.5 AFI85210.1 - 0.079 12.8 0.2 0.24 11.2 0.2 1.8 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal Fimbrial_PilY2 PF14481.6 AFI85211.1 - 0.0003 20.4 0.0 0.00034 20.2 0.0 1.1 1 0 0 1 1 1 1 Type 4 fimbrial biogenesis protein PilY2 ComP_DUS PF16732.5 AFI85212.1 - 3.9e-24 85.3 0.1 5e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 Type IV minor pilin ComP, DNA uptake sequence receptor N_methyl PF07963.12 AFI85212.1 - 6.2e-11 41.4 0.6 1.1e-10 40.6 0.6 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PMP1_2 PF08114.11 AFI85212.1 - 0.12 12.1 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 ATPase proteolipid family DDE_Tnp_1_3 PF13612.6 AFI85213.1 - 1.5e-77 259.0 0.0 2.1e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85213.1 - 5.6e-23 81.7 0.1 8.4e-22 77.9 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI85213.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain HemolysinCabind PF00353.19 AFI85214.1 - 1e-06 28.6 14.8 1e-06 28.6 14.8 2.6 2 0 0 2 2 2 1 RTX calcium-binding nonapeptide repeat (4 copies) FecR PF04773.13 AFI85214.1 - 0.0038 17.8 0.0 0.015 15.9 0.0 2.1 2 0 0 2 2 2 1 FecR protein RNA_pol_RpbG PF16992.5 AFI85215.1 - 0.004 17.2 0.1 0.0063 16.6 0.1 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Desmo_N PF06771.11 AFI85215.1 - 0.066 13.6 0.3 0.16 12.3 0.3 1.6 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus TetR_N PF00440.23 AFI85216.1 - 3.5e-10 39.5 0.0 6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_11 PF08279.12 AFI85216.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 AFI85216.1 - 0.0018 18.1 0.5 0.0045 16.8 0.5 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_AraC PF00165.23 AFI85216.1 - 0.0078 16.3 0.0 0.033 14.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_C_15 PF17918.1 AFI85216.1 - 0.015 16.0 0.6 0.31 11.8 0.0 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_10 PF04967.12 AFI85216.1 - 0.018 14.8 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.6 AFI85216.1 - 0.025 14.1 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RHH_1 PF01402.21 AFI85216.1 - 0.073 13.0 0.3 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HTH_22 PF13309.6 AFI85216.1 - 0.081 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 AFI85216.1 - 0.093 12.6 0.3 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_5 PF01022.20 AFI85216.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family AA_kinase PF00696.28 AFI85217.1 - 3.6e-44 151.2 3.9 4.2e-44 151.0 3.9 1.0 1 0 0 1 1 1 1 Amino acid kinase family PGM_PMM_I PF02878.16 AFI85218.1 - 4.5e-36 123.6 0.0 7.8e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AFI85218.1 - 7.5e-29 100.4 0.0 1.7e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AFI85218.1 - 1.4e-19 70.4 0.0 3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AFI85218.1 - 9.8e-09 35.3 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain dUTPase PF00692.19 AFI85219.1 - 3.1e-34 117.4 0.0 3.7e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF1350 PF07082.11 AFI85219.1 - 0.21 10.9 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) DFP PF04127.15 AFI85220.1 - 1.1e-69 234.0 0.1 2.7e-69 232.8 0.1 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AFI85220.1 - 1.9e-45 154.5 0.0 3.2e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Virul_fac_BrkB PF03631.15 AFI85221.1 - 4e-49 167.5 28.1 5.1e-49 167.2 28.1 1.1 1 0 0 1 1 1 1 Virulence factor BrkB Rrf2 PF02082.20 AFI85221.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Flavin_Reduct PF01613.18 AFI85221.1 - 0.075 13.1 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Flavin reductase like domain NIF3 PF01784.18 AFI85222.1 - 3.2e-56 190.7 0.1 3.9e-56 190.4 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4126 PF13548.6 AFI85223.1 - 1.1e-55 188.1 15.9 1.3e-55 187.8 15.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) CBM_5_12_2 PF14600.6 AFI85223.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Cellulose-binding domain HemY_N PF07219.13 AFI85223.1 - 0.31 11.2 2.0 0.79 9.9 2.0 1.7 1 0 0 1 1 1 0 HemY protein N-terminus DUF4131 PF13567.6 AFI85223.1 - 0.53 9.9 2.4 1.9 8.1 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF962 PF06127.11 AFI85223.1 - 0.69 10.0 7.7 0.36 10.9 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) CheR PF01739.18 AFI85224.1 - 2.7e-61 206.4 0.0 3.5e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AFI85224.1 - 2.1e-11 43.3 0.0 4.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AFI85224.1 - 1.9e-07 31.7 0.0 7.5e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85224.1 - 3.4e-07 30.9 0.0 1.1e-05 26.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI85224.1 - 1e-06 29.3 0.0 2.3e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI85224.1 - 3.6e-06 26.9 0.0 5.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI85224.1 - 0.00019 21.2 0.0 0.0013 18.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain NAS PF03059.16 AFI85224.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein TehB PF03848.14 AFI85224.1 - 0.07 12.5 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TehB adh_short PF00106.25 AFI85225.1 - 2.1e-43 148.1 0.0 2.6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AFI85225.1 - 1e-33 116.9 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AFI85225.1 - 5.9e-12 45.9 0.1 3.3e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 AFI85225.1 - 2.5e-07 30.4 0.0 1.8e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 AFI85225.1 - 3.3e-06 27.1 0.0 4.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AFI85225.1 - 4.2e-06 26.4 0.2 1.3e-05 24.7 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AFI85225.1 - 0.00016 20.9 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AFI85225.1 - 0.00068 19.3 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 AFI85225.1 - 0.0014 17.8 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 AFI85225.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.26 AFI85225.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HTH_Tnp_1 PF01527.20 AFI85227.1 - 3.5e-16 59.3 0.7 3.9e-16 59.1 0.7 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AFI85227.1 - 1.7e-07 30.8 0.5 2.7e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AFI85227.1 - 5.6e-07 29.6 0.1 1.7e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 AFI85227.1 - 5.1e-05 23.4 0.0 8.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AFI85227.1 - 0.00046 19.8 0.4 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Terminase_5 PF06056.12 AFI85227.1 - 0.00062 19.6 0.0 0.00087 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_ISL3 PF13542.6 AFI85227.1 - 0.0008 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 AFI85227.1 - 0.00089 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase LZ_Tnp_IS481 PF13011.6 AFI85227.1 - 0.0012 19.3 0.2 0.0021 18.5 0.1 1.6 1 1 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_29 PF13551.6 AFI85227.1 - 0.0013 18.7 0.1 0.0018 18.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_30 PF13556.6 AFI85227.1 - 0.0035 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Sigma70_r4 PF04545.16 AFI85227.1 - 0.0036 16.8 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 AFI85227.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_38 PF13936.6 AFI85227.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AFI85227.1 - 0.017 15.3 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_22 PF13309.6 AFI85227.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_19 PF12844.7 AFI85227.1 - 0.024 14.6 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF746 PF05344.11 AFI85227.1 - 0.039 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) CENP-B_N PF04218.13 AFI85227.1 - 0.04 13.5 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Phage_CI_repr PF07022.13 AFI85227.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Form_Nir_trans PF01226.17 AFI85228.1 - 1.4e-58 198.1 29.4 1.7e-58 197.8 29.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Cyanate_lyase PF02560.14 AFI85229.1 - 1.5e-34 117.7 0.1 3.2e-34 116.6 0.0 1.6 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 AFI85229.1 - 0.086 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Form_Nir_trans PF01226.17 AFI85230.1 - 2.5e-74 249.6 27.4 2.8e-74 249.4 27.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Yip1 PF04893.17 AFI85230.1 - 4.6 6.9 29.9 50 3.5 29.9 2.1 1 1 0 1 1 1 0 Yip1 domain AAA_2 PF07724.14 AFI85231.1 - 1.7e-59 200.8 0.1 1.7e-55 187.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AFI85231.1 - 7.3e-35 119.0 1.9 7.3e-35 119.0 1.9 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 AFI85231.1 - 3.4e-26 91.1 0.2 3.4e-26 91.1 0.2 2.8 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AFI85231.1 - 1.4e-25 90.3 0.3 2.8e-13 50.4 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 AFI85231.1 - 7e-24 83.7 1.7 3.8e-12 46.1 0.2 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 AFI85231.1 - 4.8e-19 68.7 0.0 5.4e-13 49.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AFI85231.1 - 1.1e-11 45.4 7.5 7.8e-05 23.1 0.0 5.1 5 1 0 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 AFI85231.1 - 6.1e-10 39.5 1.2 0.0026 18.0 0.0 4.3 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 AFI85231.1 - 4.7e-09 36.2 0.1 1e-05 25.3 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 AFI85231.1 - 1.5e-07 31.3 0.0 0.00064 19.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 AFI85231.1 - 8.7e-07 29.0 0.0 0.043 13.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 AFI85231.1 - 9.7e-07 28.4 0.1 0.0019 17.6 0.1 3.7 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 AFI85231.1 - 5.6e-06 26.2 0.0 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 AFI85231.1 - 1.1e-05 25.3 0.8 0.48 10.2 0.4 4.6 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 AFI85231.1 - 3.8e-05 23.7 2.6 1.6 8.6 0.0 4.7 3 2 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AFI85231.1 - 4.2e-05 23.1 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AFI85231.1 - 8.3e-05 23.1 2.7 0.59 10.7 0.0 4.2 5 0 0 5 5 4 2 AAA domain Mg_chelatase PF01078.21 AFI85231.1 - 0.00011 21.6 0.2 0.64 9.4 0.0 3.6 2 2 1 4 4 4 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 AFI85231.1 - 0.00018 21.7 0.0 0.81 9.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 AFI85231.1 - 0.00026 21.4 0.0 0.89 10.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 AFI85231.1 - 0.00069 19.6 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 AFI85231.1 - 0.0011 18.9 0.7 1.7 8.5 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 AFI85231.1 - 0.0012 19.3 0.7 1.1 9.7 0.0 3.8 3 1 0 3 3 3 1 ABC transporter AAA_25 PF13481.6 AFI85231.1 - 0.0012 18.4 0.0 0.34 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 AFI85231.1 - 0.0015 18.5 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 AFI85231.1 - 0.0016 18.3 0.1 1.3 8.9 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 AFI85231.1 - 0.0017 17.5 0.2 0.69 9.0 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) ResIII PF04851.15 AFI85231.1 - 0.0021 18.1 0.0 1.7 8.6 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AFI85231.1 - 0.0066 16.8 0.2 0.73 10.2 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AFI85231.1 - 0.0079 15.9 0.0 4.1 7.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 AFI85231.1 - 0.0099 16.1 1.9 4.4 7.5 0.0 3.8 4 0 0 4 4 3 0 AAA domain DNA_pol3_delta2 PF13177.6 AFI85231.1 - 0.012 15.5 0.0 3.4 7.4 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 AFI85231.1 - 0.013 15.5 0.4 3.8 7.4 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 AFI85231.1 - 0.021 15.0 0.7 11 6.2 0.0 3.2 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 AFI85231.1 - 0.036 13.4 0.0 8.2 5.7 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 AFI85231.1 - 0.036 13.8 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 AFI85231.1 - 0.043 13.5 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 AFI85231.1 - 0.071 13.2 0.4 1e+02 2.9 0.0 4.0 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 AFI85231.1 - 0.071 13.6 21.8 0.82 10.1 0.0 4.3 2 1 1 3 3 2 0 AAA domain TetR_C_11 PF16859.5 AFI85231.1 - 0.072 13.4 4.6 1.9 8.8 0.2 4.0 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PduV-EutP PF10662.9 AFI85231.1 - 0.15 11.8 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 AFI85231.1 - 1.8 8.6 5.3 18 5.3 0.0 3.7 3 1 1 4 4 4 0 Helicase HerA, central domain Fib_alpha PF08702.10 AFI85231.1 - 5 7.3 6.9 27 4.9 1.1 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lip_A_acyltrans PF03279.13 AFI85232.1 - 1.1e-75 254.6 0.1 1.2e-75 254.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase TcpA PF05946.12 AFI85232.1 - 0.19 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Mito_fiss_Elm1 PF06258.11 AFI85233.1 - 6.7e-60 202.8 0.0 8.2e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Sigma54_AID PF00309.20 AFI85233.1 - 0.31 10.9 2.8 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Glycos_transf_1 PF00534.20 AFI85234.1 - 1.1e-22 80.4 0.0 1.7e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI85234.1 - 1.4e-22 80.5 0.1 1.3e-21 77.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AFI85234.1 - 4.9e-15 56.2 0.0 8.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AFI85234.1 - 9.1e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like WD40_like PF17005.5 AFI85234.1 - 0.061 12.6 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain PIGA PF08288.12 AFI85234.1 - 0.11 13.1 0.0 0.29 11.8 0.0 1.8 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) Glyco_trans_1_4 PF13692.6 AFI85235.1 - 1.9e-21 76.9 0.0 2.9e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AFI85235.1 - 5.7e-21 74.8 0.0 1.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI85235.1 - 4.5e-16 59.3 0.6 1.4e-15 57.7 0.6 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI85235.1 - 3e-10 40.8 0.4 1e-08 35.8 0.2 3.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AFI85235.1 - 0.00011 22.2 0.1 0.0002 21.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 AFI85235.1 - 0.0003 20.6 0.2 0.061 13.0 0.0 2.7 1 1 0 2 2 2 1 Starch synthase catalytic domain Hus1 PF04005.12 AFI85235.1 - 0.095 11.8 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Hus1-like protein Glyco_trans_1_2 PF13524.6 AFI85235.1 - 0.099 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_9 PF01075.17 AFI85236.1 - 5.6e-19 68.4 0.1 7.6e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_4 PF13439.6 AFI85236.1 - 0.023 14.7 0.2 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Wzy_C PF04932.15 AFI85237.1 - 3.2e-15 56.1 4.8 3.2e-15 56.1 4.8 3.7 2 1 0 3 3 3 1 O-Antigen ligase Sid-5 PF17204.3 AFI85237.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.4 2 1 1 3 3 3 0 Sid-5 family Acyltransferase PF01553.21 AFI85238.1 - 1.4e-19 70.0 0.0 1.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase DUF374 PF04028.13 AFI85238.1 - 0.0098 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF374) Sua5_yciO_yrdC PF01300.18 AFI85239.1 - 7.7e-45 152.6 0.0 8.9e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination ThiP_synth PF10120.9 AFI85239.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Thiamine-phosphate synthase PHP PF02811.19 AFI85240.1 - 2.6e-10 40.9 0.0 3.8e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 PHP domain TOBE_2 PF08402.10 AFI85240.1 - 0.0049 17.0 0.5 0.013 15.6 0.1 1.8 2 0 0 2 2 2 1 TOBE domain PHP_C PF13263.6 AFI85240.1 - 0.12 12.2 0.3 19 5.1 0.0 2.4 2 0 0 2 2 2 0 PHP-associated TOBE PF03459.17 AFI85240.1 - 0.43 10.9 2.4 0.44 10.9 0.6 1.9 2 0 0 2 2 2 0 TOBE domain IspA PF04279.15 AFI85241.1 - 6.6e-65 218.6 15.4 7.5e-65 218.4 15.4 1.0 1 0 0 1 1 1 1 Intracellular septation protein A DUF2976 PF11190.8 AFI85241.1 - 0.38 10.6 4.7 4.6 7.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) MerC PF03203.14 AFI85241.1 - 0.54 10.7 13.9 2 8.9 6.9 2.6 1 1 2 3 3 3 0 MerC mercury resistance protein DUF2569 PF10754.9 AFI85241.1 - 0.76 10.2 11.2 0.65 10.4 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2614 PF11023.8 AFI85241.1 - 1.5 8.9 6.7 0.81 9.8 1.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain YCII PF03795.14 AFI85242.1 - 1e-26 93.2 0.0 1.1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF1330 PF07045.11 AFI85242.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) BolA PF01722.18 AFI85243.1 - 4.9e-30 103.6 0.0 6e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein PilZ PF07238.14 AFI85244.1 - 1.5e-14 54.1 0.1 1.2e-07 32.0 0.0 2.6 2 0 0 2 2 2 2 PilZ domain PAP_fibrillin PF04755.12 AFI85244.1 - 0.0041 17.1 0.9 2.8 7.8 0.1 2.6 1 1 1 2 2 2 2 PAP_fibrillin PmbA_TldD PF01523.16 AFI85245.1 - 1.7e-68 231.5 0.0 1.7e-68 231.5 0.0 1.5 2 0 0 2 2 2 1 Putative modulator of DNA gyrase Prok-JAB PF14464.6 AFI85246.1 - 1.3e-11 44.3 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ThiF PF00899.21 AFI85247.1 - 3.7e-58 196.8 0.1 4.6e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AFI85247.1 - 0.001 19.3 1.0 0.0043 17.3 1.3 1.9 2 1 0 2 2 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 AFI85247.1 - 0.012 15.3 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AFI85247.1 - 0.025 14.6 0.5 0.12 12.4 0.1 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AFI85247.1 - 0.037 13.6 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 AFI85247.1 - 0.045 14.0 0.4 0.12 12.6 0.1 1.8 1 1 1 2 2 2 0 TrkA-N domain KR PF08659.10 AFI85247.1 - 0.09 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.19 AFI85247.1 - 0.11 11.9 0.2 0.2 11.0 0.1 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Urocanase PF01175.18 AFI85247.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Gp_dh_N PF00044.24 AFI85247.1 - 0.13 12.6 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DAO PF01266.24 AFI85247.1 - 0.62 9.6 5.7 5.2 6.5 3.4 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AFI85247.1 - 9.7 5.3 7.2 4.1 6.6 2.9 1.8 1 1 1 2 2 2 0 FAD binding domain MTS PF05175.14 AFI85248.1 - 4.3e-17 62.2 0.0 8.3e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PrmC_N PF17827.1 AFI85248.1 - 1.5e-16 60.7 1.6 2.4e-16 60.1 0.8 1.9 2 0 0 2 2 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 AFI85248.1 - 6.5e-12 45.5 0.0 9.7e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AFI85248.1 - 3.6e-07 29.9 0.0 6.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AFI85248.1 - 1.4e-06 28.9 0.0 3.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AFI85248.1 - 4.8e-05 23.9 0.0 0.00064 20.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AFI85248.1 - 0.00022 21.0 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 AFI85248.1 - 0.00038 20.3 0.0 0.004 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AFI85248.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85248.1 - 0.00082 20.1 0.0 0.038 14.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AFI85248.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 AFI85248.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 AFI85248.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 AFI85248.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Response_reg PF00072.24 AFI85249.1 - 5.4e-22 78.1 0.6 1.2e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Bac_GDH PF05088.12 AFI85249.1 - 0.061 10.8 12.2 0.067 10.7 12.2 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase ARGLU PF15346.6 AFI85249.1 - 6 6.7 16.2 0.41 10.5 8.5 2.5 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 DUF3301 PF11743.8 AFI85250.1 - 3.8e-33 113.0 0.2 4.1e-33 112.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3301) Methyltrans_RNA PF04452.14 AFI85251.1 - 4.6e-71 238.8 0.0 5.1e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Inositol_P PF00459.25 AFI85252.1 - 9.5e-50 169.6 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AFI85252.1 - 0.0027 17.2 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Cu-oxidase_4 PF02578.15 AFI85253.1 - 4.9e-75 252.1 0.0 5.6e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase DUF3404 PF11884.8 AFI85253.1 - 0.13 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) FtsK_alpha PF17854.1 AFI85253.1 - 0.21 11.7 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK alpha domain Zip PF02535.22 AFI85254.1 - 4e-36 124.9 26.4 1.1e-28 100.4 10.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter TatC PF00902.18 AFI85254.1 - 0.00031 20.6 2.6 0.00063 19.6 2.6 1.6 1 1 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF4514 PF14986.6 AFI85254.1 - 5.2 7.1 7.1 30 4.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) Glyco_transf_9 PF01075.17 AFI85255.1 - 1.1e-70 237.8 0.0 1.4e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Epimerase_2 PF02350.19 AFI85255.1 - 0.24 10.2 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glycos_transf_1 PF00534.20 AFI85256.1 - 1.2e-33 116.1 0.0 3.8e-33 114.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI85256.1 - 9e-26 90.9 0.0 7.3e-24 84.7 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI85256.1 - 2.7e-07 30.7 0.0 8.4e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Wzy_C PF04932.15 AFI85257.1 - 3.5e-09 36.5 9.7 3.5e-09 36.5 9.7 4.5 2 2 1 3 3 3 1 O-Antigen ligase UL42 PF17638.2 AFI85257.1 - 0.26 11.3 1.6 0.65 10.0 0.1 2.4 2 0 0 2 2 2 0 HCMV UL42 Carbam_trans_C PF16861.5 AFI85259.1 - 1.6e-68 229.6 0.0 2.3e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 AFI85259.1 - 6.8e-55 187.1 0.0 8.9e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus FlpD PF02662.16 AFI85259.1 - 0.019 15.0 0.0 0.06 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Glyco_transf_9 PF01075.17 AFI85260.1 - 2.7e-11 43.3 0.0 6.5e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_4 PF13439.6 AFI85260.1 - 0.013 15.6 0.0 0.84 9.6 0.0 2.8 2 1 1 3 3 3 0 Glycosyltransferase Family 4 EarP PF10093.9 AFI85260.1 - 0.045 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP Acyl_transf_2 PF02273.15 AFI85260.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase DUF354 PF04007.12 AFI85260.1 - 0.082 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF354) Glycos_transf_1 PF00534.20 AFI85261.1 - 9.1e-31 106.7 0.0 1.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AFI85261.1 - 9.4e-22 77.9 0.0 1.6e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AFI85261.1 - 0.0059 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI85261.1 - 0.032 14.2 0.0 0.29 11.1 0.0 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Kdo PF06293.14 AFI85262.1 - 2.4e-15 56.5 0.8 4.6e-15 55.5 0.8 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 AFI85262.1 - 1.1e-07 31.5 0.1 4.2e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 AFI85262.1 - 1.6e-06 27.9 0.0 0.13 11.8 0.0 3.2 3 0 0 3 3 3 2 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 AFI85262.1 - 6.9e-05 22.9 8.0 0.23 11.4 0.8 3.8 2 2 1 3 3 3 3 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 AFI85262.1 - 0.00019 20.8 0.0 0.00044 19.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 AFI85262.1 - 0.00035 20.2 0.0 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 RIO1 family AceK PF06315.11 AFI85262.1 - 0.0098 14.4 0.0 0.033 12.7 0.0 1.7 1 1 1 2 2 2 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) PIP49_C PF12260.8 AFI85262.1 - 0.035 13.8 1.2 0.83 9.3 0.3 2.7 2 1 1 3 3 3 0 Protein-kinase domain of FAM69 Kdo PF06293.14 AFI85263.1 - 2.4e-47 161.0 0.2 3.2e-47 160.6 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SIS_2 PF13580.6 AFI85264.1 - 2.3e-25 89.2 0.1 3.1e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AFI85264.1 - 6.3e-09 35.8 0.2 2.4e-07 30.7 0.0 2.3 1 1 0 2 2 2 1 SIS domain DAO PF01266.24 AFI85265.1 - 1.6e-09 37.9 0.0 3.8e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AFI85265.1 - 0.00016 21.8 0.7 0.0003 21.0 0.3 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AFI85265.1 - 0.00066 19.0 0.1 0.0009 18.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AFI85265.1 - 0.0057 16.0 0.1 0.0083 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 AFI85265.1 - 0.024 13.7 0.3 0.042 12.9 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 AFI85265.1 - 0.03 13.0 0.0 0.079 11.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 AFI85265.1 - 0.037 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 AFI85265.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Aldo_ket_red PF00248.21 AFI85266.1 - 1.4e-30 106.5 0.0 4.7e-29 101.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family NRD1_2 PF01995.16 AFI85266.1 - 0.036 13.3 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 ParE-like_toxin PF15781.5 AFI85267.1 - 6e-36 122.3 0.9 6.8e-36 122.1 0.9 1.0 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system YafQ_toxin PF15738.5 AFI85267.1 - 0.17 12.2 2.1 1.6 9.1 1.9 2.1 1 1 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ ParD_like PF11903.8 AFI85268.1 - 4.3e-15 55.5 0.0 4.9e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system PhdYeFM_antitox PF02604.19 AFI85269.1 - 9.6e-08 31.7 0.0 1.7e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system RelB_N PF18506.1 AFI85269.1 - 0.00016 21.4 0.3 0.0002 21.1 0.3 1.2 1 0 0 1 1 1 1 RelB Antitoxin alpha helical domain HEPN_Swt1 PF18731.1 AFI85270.1 - 0.019 15.3 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 Swt1-like HEPN PilZ PF07238.14 AFI85272.1 - 0.068 13.5 0.0 0.074 13.4 0.0 1.1 1 0 0 1 1 1 0 PilZ domain LigB PF02900.18 AFI85273.1 - 3e-12 46.2 0.0 3.3e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CcdB PF01845.17 AFI85274.1 - 2.4e-34 117.5 0.0 2.7e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 CcdB protein CcdA PF07362.12 AFI85275.1 - 3.7e-31 107.4 0.8 4.1e-31 107.2 0.8 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA IF-2B PF01008.17 AFI85275.1 - 0.0054 16.0 0.2 0.0063 15.8 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1525 PF07511.11 AFI85275.1 - 0.07 13.3 0.1 0.077 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) MAAL_C PF07476.11 AFI85275.1 - 0.11 11.6 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PfkB PF00294.24 AFI85276.1 - 2.3e-48 165.1 2.1 3.3e-48 164.5 2.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AFI85276.1 - 2.1e-15 57.2 0.0 4.8e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 AFI85276.1 - 8e-13 48.3 0.9 2.7e-12 46.6 0.8 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 AFI85276.1 - 0.00034 20.2 0.3 0.00068 19.2 0.3 1.4 1 0 0 1 1 1 1 Carbohydrate kinase Pantoate_ligase PF02569.15 AFI85276.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase AAA_33 PF13671.6 AFI85276.1 - 0.034 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FAD_syn PF06574.12 AFI85276.1 - 0.1 12.5 0.1 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase Glyco_transf_9 PF01075.17 AFI85277.1 - 5.9e-53 179.7 0.1 8.1e-53 179.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) UPF0181 PF03701.14 AFI85277.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) APH PF01636.23 AFI85278.1 - 3e-27 96.1 1.7 4.2e-27 95.6 1.7 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AFI85278.1 - 1.7e-05 24.6 0.1 2.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2782 PF11191.8 AFI85279.1 - 9e-30 102.7 0.2 9.7e-30 102.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2782) DNA_pol_A PF00476.20 AFI85280.1 - 6.9e-157 522.3 0.5 1.2e-156 521.6 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AFI85280.1 - 4.4e-57 192.4 0.0 7.5e-57 191.7 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 AFI85280.1 - 1.1e-43 149.0 1.3 7.5e-43 146.3 0.3 2.4 2 0 0 2 2 2 1 3'-5' exonuclease 5_3_exonuc PF01367.20 AFI85280.1 - 7.7e-32 109.8 1.4 4.9e-31 107.2 0.2 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 AFI85280.1 - 0.052 13.7 0.0 0.46 10.6 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif Terminase_4 PF05119.12 AFI85280.1 - 0.12 12.8 0.0 0.44 11.0 0.0 2.0 1 0 0 1 1 1 0 Phage terminase, small subunit MCPsignal PF00015.21 AFI85281.1 - 1.8e-38 132.0 23.8 1.8e-38 132.0 23.8 3.7 2 1 2 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain Nairovirus_M PF07948.11 AFI85281.1 - 0.019 13.2 0.1 0.038 12.2 0.1 1.4 1 0 0 1 1 1 0 Nairovirus M polyprotein-like Hydrophobin_2 PF06766.11 AFI85281.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal hydrophobin STAS PF01740.21 AFI85281.1 - 0.029 14.0 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 STAS domain RHH_5 PF07878.11 AFI85281.1 - 0.063 13.2 0.7 0.18 11.7 0.7 1.9 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF2062 PF09835.9 AFI85281.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF5113 PF17140.4 AFI85281.1 - 0.31 10.8 4.3 9.4 6.0 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) T2SSF PF00482.23 AFI85281.1 - 2.2 8.2 14.1 7.4 6.5 1.5 4.6 2 1 1 4 4 4 0 Type II secretion system (T2SS), protein F COG2 PF06148.11 AFI85281.1 - 4.5 7.4 29.7 1.4 9.0 2.8 5.2 2 1 3 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M50 PF02163.22 AFI85281.1 - 5.7 6.1 8.0 99 2.1 8.0 2.8 1 1 0 1 1 1 0 Peptidase family M50 DUF1730 PF08331.10 AFI85282.1 - 2.6e-22 78.5 0.0 4.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 AFI85282.1 - 3.9e-21 75.7 3.6 6.4e-21 75.1 3.6 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AFI85282.1 - 7.7e-07 29.6 5.0 1.5e-06 28.7 5.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI85282.1 - 1.7e-05 24.9 1.1 0.0059 16.8 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI85282.1 - 4.3e-05 23.5 4.5 0.036 14.2 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI85282.1 - 0.00013 21.8 8.6 0.022 14.8 3.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AFI85282.1 - 0.00059 19.9 6.8 0.11 12.6 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AFI85282.1 - 0.0011 18.7 11.3 0.0023 17.7 3.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 AFI85282.1 - 0.031 14.4 12.8 0.64 10.2 5.1 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 AFI85282.1 - 0.076 14.0 9.6 2.8 9.1 2.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AFI85282.1 - 0.8 9.9 5.7 2.3 8.4 1.9 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI85282.1 - 1.5 9.5 9.7 10 6.9 4.7 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AFI85282.1 - 1.7 9.2 9.7 30 5.2 9.7 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AFI85282.1 - 2.8 8.5 6.3 8.4 7.0 6.3 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Carb_kinase PF01256.17 AFI85283.1 - 6.5e-59 199.3 0.8 1.9e-58 197.8 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 AFI85283.1 - 2.8e-40 138.0 0.2 4.5e-40 137.3 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus HK PF02110.15 AFI85283.1 - 7.9e-05 22.2 0.0 0.00051 19.5 0.0 2.0 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TsaE PF02367.17 AFI85284.1 - 2.1e-40 137.6 0.0 2.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AFI85284.1 - 0.013 15.8 0.0 0.015 15.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AFI85284.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AFI85284.1 - 0.058 13.6 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AFI85284.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AFI85284.1 - 0.15 11.6 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Amidase_3 PF01520.18 AFI85285.1 - 5.2e-50 170.0 0.0 1.1e-49 168.9 0.0 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 AFI85285.1 - 2.9e-19 69.0 1.4 2.4e-17 62.8 0.3 2.3 1 1 1 2 2 2 2 AMIN domain LysM PF01476.20 AFI85285.1 - 1e-12 47.9 0.0 2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 LysM domain DNA_mis_repair PF01119.19 AFI85286.1 - 1e-37 128.4 0.0 2.2e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 AFI85286.1 - 2.3e-13 50.1 0.7 6.2e-13 48.7 0.7 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 AFI85286.1 - 2e-12 47.1 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AFI85286.1 - 1.7e-08 35.0 0.0 4.2e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC2_membrane_3 PF12698.7 AFI85287.1 - 0.018 14.1 0.1 0.054 12.6 0.1 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF761 PF05553.11 AFI85287.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.4 3 0 0 3 3 3 0 Cotton fibre expressed protein ACR_tran PF00873.19 AFI85288.1 - 2.6e-230 767.0 16.0 3.2e-230 766.7 16.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI85288.1 - 4.6e-11 42.2 29.0 2e-06 27.0 8.2 2.3 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AFI85288.1 - 0.00074 18.9 23.8 0.0015 18.0 9.8 2.4 2 0 0 2 2 2 2 Protein export membrane protein DUF5589 PF17672.1 AFI85288.1 - 0.62 10.0 3.4 14 5.6 0.4 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5589) AIM24 PF01987.17 AFI85289.1 - 0.032 14.0 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 Imm12 PF15560.6 AFI85290.1 - 0.061 13.3 0.0 0.063 13.2 0.0 1.0 1 0 0 1 1 1 0 Immunity protein 12 Porin_4 PF13609.6 AFI85292.1 - 3.3e-21 76.3 44.4 4.3e-21 76.0 44.4 1.0 1 0 0 1 1 1 1 Gram-negative porin Dak2 PF02734.17 AFI85293.1 - 2.3e-49 167.6 8.5 2.9e-49 167.3 8.5 1.1 1 0 0 1 1 1 1 DAK2 domain PDDEXK_3 PF13366.6 AFI85294.1 - 5.9e-44 149.2 0.3 6.6e-44 149.1 0.3 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 AFI85294.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF83 Dak1 PF02733.17 AFI85295.1 - 7.6e-122 406.1 1.2 8.7e-122 405.9 1.2 1.0 1 0 0 1 1 1 1 Dak1 domain Hydrolase_6 PF13344.6 AFI85296.1 - 1.9e-28 98.5 0.0 3.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI85296.1 - 2.7e-24 85.0 0.0 7.2e-23 80.4 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 AFI85296.1 - 4.4e-13 50.0 0.3 2e-11 44.6 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AFI85296.1 - 3.4e-12 46.8 0.0 4.4e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AFI85296.1 - 0.0019 18.0 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 AFI85296.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase OMPdecase PF00215.24 AFI85297.1 - 7.8e-29 100.9 3.4 8.9e-29 100.7 3.4 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim PF00834.19 AFI85297.1 - 6.9e-06 25.6 1.4 0.00017 21.1 0.7 2.3 1 1 1 2 2 2 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AFI85297.1 - 5.7e-05 23.0 0.5 0.00016 21.5 0.4 1.7 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain HMGL-like PF00682.19 AFI85297.1 - 0.00016 21.3 0.1 0.012 15.2 0.2 2.1 1 1 1 2 2 2 2 HMGL-like PRAI PF00697.22 AFI85297.1 - 0.019 14.8 0.7 0.03 14.1 0.7 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Choline_sulf_C PF12411.8 AFI85298.1 - 0.0051 16.6 3.5 12 5.7 0.1 3.7 1 1 2 3 3 3 3 Choline sulfatase enzyme C terminal ATP_synth_reg PF14960.6 AFI85298.1 - 0.0074 15.8 0.1 3.9 7.0 0.0 3.5 1 1 3 4 4 4 1 ATP synthase regulation TAL_FSA PF00923.19 AFI85299.1 - 6.1e-97 324.4 0.0 6.9e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase OMPdecase PF00215.24 AFI85300.1 - 3.2e-27 95.6 5.8 3.8e-27 95.3 5.8 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim PF00834.19 AFI85300.1 - 7e-06 25.6 2.9 1.6e-05 24.4 1.1 2.1 1 1 1 2 2 2 1 Ribulose-phosphate 3 epimerase family HMGL-like PF00682.19 AFI85300.1 - 1.1e-05 25.2 0.2 0.0008 19.0 0.2 2.0 1 1 1 2 2 2 2 HMGL-like QRPTase_C PF01729.19 AFI85300.1 - 0.00012 21.9 0.4 0.00036 20.4 0.3 1.8 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.17 AFI85300.1 - 0.049 13.1 1.0 0.074 12.5 0.9 1.4 1 1 0 1 1 1 0 PcrB family TMP-TENI PF02581.17 AFI85300.1 - 0.11 11.8 7.2 0.39 10.0 1.3 2.2 1 1 1 2 2 2 0 Thiamine monophosphate synthase SIS PF01380.22 AFI85301.1 - 4.8e-19 68.5 0.0 7.3e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AFI85301.1 - 9.1e-07 29.0 0.2 7.1e-06 26.1 0.1 2.0 1 1 0 2 2 2 1 SIS domain DUF2529 PF10740.9 AFI85301.1 - 0.0074 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2529) ApbA PF02558.16 AFI85301.1 - 0.017 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Flavoprotein PF02441.19 AFI85301.1 - 0.051 13.3 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Flavoprotein Aconitase PF00330.20 AFI85302.1 - 1.8e-160 534.9 0.6 2.1e-160 534.7 0.6 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) MTS PF05175.14 AFI85303.1 - 2.1e-15 56.7 0.0 3.1e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 AFI85303.1 - 7.1e-10 38.9 0.0 9.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI85303.1 - 4.2e-06 27.4 0.0 8.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AFI85303.1 - 9.1e-06 25.3 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 AFI85303.1 - 6.9e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.12 AFI85303.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase PrmC_N PF17827.1 AFI85303.1 - 0.0003 21.3 0.4 0.00072 20.1 0.1 1.8 2 0 0 2 2 1 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 AFI85303.1 - 0.00048 20.0 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AFI85303.1 - 0.00083 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 AFI85303.1 - 0.0011 18.9 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AFI85303.1 - 0.0042 16.7 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 AFI85303.1 - 0.018 15.8 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AFI85303.1 - 0.072 12.4 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltrans_SAM PF10672.9 AFI85303.1 - 0.089 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase AviRa PF11599.8 AFI85303.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.5 1 1 0 1 1 1 0 RRNA methyltransferase AviRa GGDEF PF00990.21 AFI85304.1 - 1.3e-39 135.6 0.8 3.2e-39 134.3 0.1 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AFI85304.1 - 2.2e-34 118.0 0.0 3.6e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain GGDEF_2 PF17853.1 AFI85304.1 - 1.4e-06 28.6 0.1 6.6e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 GGDEF-like domain MutH PF02976.15 AFI85305.1 - 1e-30 105.8 0.0 1.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair enzyme MutH MvaI_BcnI PF15515.6 AFI85305.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.4 1 1 0 1 1 1 1 MvaI/BcnI restriction endonuclease family ABC_tran PF00005.27 AFI85306.1 - 6.7e-32 110.9 0.0 1.3e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI85306.1 - 2.5e-12 47.2 1.3 4.7e-07 29.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AFI85306.1 - 4.2e-05 23.4 0.0 0.097 12.4 0.7 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AFI85306.1 - 0.0019 17.9 0.3 0.0047 16.6 0.3 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain DUF4162 PF13732.6 AFI85306.1 - 0.0022 18.7 0.2 0.0075 17.0 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4162) DUF87 PF01935.17 AFI85306.1 - 0.0033 17.6 0.1 0.0078 16.3 0.1 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_30 PF13604.6 AFI85306.1 - 0.0038 17.0 0.1 0.019 14.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 AFI85306.1 - 0.0054 17.3 1.3 0.0058 17.2 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AFI85306.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain CbiA PF01656.23 AFI85306.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SMC_N PF02463.19 AFI85306.1 - 0.013 14.9 0.0 0.5 9.8 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 AFI85306.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AFI85306.1 - 0.026 14.8 0.4 0.3 11.3 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AFI85306.1 - 0.027 14.1 0.1 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 AFI85306.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 AFI85306.1 - 0.072 13.0 0.2 0.25 11.2 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 AFI85306.1 - 0.086 13.1 0.0 0.4 10.9 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit T4SS-DNA_transf PF02534.14 AFI85306.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ABC2_membrane PF01061.24 AFI85307.1 - 2.2e-34 118.7 25.4 2.2e-34 118.7 25.4 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AFI85307.1 - 6.2e-05 22.3 28.8 6.2e-05 22.3 28.8 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein EMP70 PF02990.16 AFI85307.1 - 9.8 4.7 13.2 7.7 5.1 11.4 1.6 1 1 1 2 2 2 0 Endomembrane protein 70 Dus PF01207.17 AFI85308.1 - 1.3e-85 287.2 0.0 1.6e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PcrB PF01884.17 AFI85308.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 PcrB family His_biosynth PF00977.21 AFI85308.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF45 PF01863.17 AFI85309.1 - 1.4e-57 195.1 8.9 1.5e-57 195.0 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AFI85309.1 - 0.00067 19.8 2.7 0.0012 19.0 2.7 1.3 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 AFI85309.1 - 0.016 15.1 0.5 0.024 14.5 0.5 1.3 1 0 0 1 1 1 0 SprT-like family Transposase_20 PF02371.16 AFI85309.1 - 0.095 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family S-AdoMet_synt_C PF02773.16 AFI85310.1 - 5.5e-69 230.5 0.3 2.4e-68 228.4 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AFI85310.1 - 2.6e-46 156.7 0.0 5.5e-46 155.7 0.0 1.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AFI85310.1 - 1.5e-42 144.3 0.2 3e-42 143.3 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoHcyase PF05221.17 AFI85311.1 - 4.2e-139 462.8 0.0 2.7e-74 250.0 0.6 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AFI85311.1 - 9.2e-84 279.4 3.1 1.4e-83 278.8 3.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AFI85311.1 - 6.7e-10 38.6 0.3 1.6e-09 37.4 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AFI85311.1 - 4.3e-05 23.2 0.1 7.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 AFI85311.1 - 0.00045 19.6 2.2 0.0026 17.1 2.2 2.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 AFI85311.1 - 0.0012 19.2 0.5 0.0033 17.8 0.5 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 AFI85311.1 - 0.0054 17.0 0.2 0.02 15.1 0.2 2.1 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 AFI85311.1 - 0.041 13.9 0.2 0.079 13.0 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AFI85311.1 - 0.084 13.5 0.6 0.29 11.7 0.3 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AFI85311.1 - 0.093 12.6 1.5 0.39 10.6 0.3 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0180 PF03698.13 AFI85311.1 - 0.16 12.2 0.3 0.83 9.9 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) AlaDh_PNT_C PF01262.21 AFI85311.1 - 0.2 10.9 2.3 0.46 9.7 2.3 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MTHFR PF02219.17 AFI85312.1 - 2e-92 309.6 0.0 2.2e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase BPD_transp_1 PF00528.22 AFI85313.1 - 3.8e-14 52.8 15.8 3.8e-14 52.8 15.8 1.4 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AFI85314.1 - 1.5e-30 106.5 0.0 2.4e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI85314.1 - 1.9e-09 37.8 1.7 0.00025 20.9 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE PF03459.17 AFI85314.1 - 4.9e-09 36.4 0.1 1.1e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 TOBE domain AAA_15 PF13175.6 AFI85314.1 - 2.9e-05 24.0 0.1 0.2 11.4 0.0 2.1 1 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AFI85314.1 - 6.6e-05 22.5 0.5 0.0014 18.1 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AFI85314.1 - 0.012 15.9 0.2 0.38 11.0 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TOBE_2 PF08402.10 AFI85314.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 TOBE domain AAA_29 PF13555.6 AFI85314.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AFI85314.1 - 0.026 14.9 0.4 0.057 13.8 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AFI85314.1 - 0.037 14.3 0.7 0.15 12.4 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AFI85314.1 - 0.045 14.3 0.1 0.073 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AFI85314.1 - 0.052 13.5 0.0 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 AFI85314.1 - 0.094 12.3 0.2 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 AFI85314.1 - 0.095 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Sigma54_DBD PF04552.13 AFI85315.1 - 8e-71 236.9 0.3 1.6e-70 236.0 0.3 1.5 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 AFI85315.1 - 3.3e-60 203.0 2.3 7.2e-60 201.9 2.3 1.6 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 AFI85315.1 - 7.7e-13 48.1 10.2 7.7e-13 48.1 10.2 2.6 3 0 0 3 3 3 1 Sigma-54 factor, Activator interacting domain (AID) CCDC14 PF15254.6 AFI85315.1 - 0.013 14.2 0.5 0.021 13.5 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 HTH_Tnp_Tc3_2 PF01498.18 AFI85315.1 - 0.023 15.0 0.3 5 7.4 0.0 3.4 3 1 0 3 3 3 0 Transposase MarR PF01047.22 AFI85315.1 - 0.05 13.5 0.2 14 5.7 0.1 3.0 2 0 0 2 2 2 0 MarR family Ribosomal_S30AE PF02482.19 AFI85316.1 - 2.1e-26 92.5 2.8 2.6e-26 92.2 2.8 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein PTS_EIIA_2 PF00359.22 AFI85317.1 - 2.2e-38 131.4 0.1 2.5e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Hpr_kinase_C PF07475.12 AFI85318.1 - 3.2e-28 98.4 0.0 3.5e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 AFI85318.1 - 0.0014 19.0 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Baculo_LEF-3 PF05847.11 AFI85318.1 - 0.0093 15.2 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus late expression factor 3 (LEF-3) AAA_24 PF13479.6 AFI85318.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AFI85318.1 - 0.022 14.5 0.1 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AFI85318.1 - 0.024 14.9 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 AFI85318.1 - 0.039 14.2 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 AFI85318.1 - 0.051 13.5 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 AFI85318.1 - 0.052 13.5 0.1 0.79 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AFI85318.1 - 0.086 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 AFI85318.1 - 0.087 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 AFI85318.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Ras PF00071.22 AFI85318.1 - 0.23 11.1 0.1 2 8.0 0.0 2.0 2 0 0 2 2 2 0 Ras family EIIA-man PF03610.16 AFI85319.1 - 3.1e-10 40.3 0.0 3.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 PTS system fructose IIA component PTS-HPr PF00381.19 AFI85320.1 - 2.6e-30 104.5 0.6 2.8e-30 104.4 0.6 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site CinA_KH PF18146.1 AFI85320.1 - 0.03 14.5 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain PEP-utilizers_C PF02896.18 AFI85321.1 - 6.2e-109 363.6 0.1 1.4e-108 362.5 0.0 1.6 2 0 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 AFI85321.1 - 2.1e-27 95.6 0.0 5.3e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 AFI85321.1 - 1.1e-22 79.5 0.6 2.4e-22 78.4 0.6 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DDE_Tnp_1_3 PF13612.6 AFI85322.1 - 1.9e-77 258.6 0.0 2.7e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85322.1 - 7.9e-23 81.2 0.1 1.1e-21 77.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI85322.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain MgtE_N PF03448.17 AFI85323.1 - 4.4e-27 94.7 0.9 4.1e-26 91.5 0.1 2.4 2 0 0 2 2 2 1 MgtE intracellular N domain MgtE PF01769.16 AFI85323.1 - 1.1e-25 90.4 10.3 1.1e-25 90.4 10.3 1.7 2 0 0 2 2 2 1 Divalent cation transporter CBS PF00571.28 AFI85323.1 - 1.3e-13 51.2 9.0 6.2e-07 29.8 0.1 3.2 3 1 0 3 3 3 2 CBS domain DUF3042 PF11240.8 AFI85323.1 - 0.73 9.9 4.3 2.6 8.1 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Chorismate_synt PF01264.21 AFI85324.1 - 3e-136 453.5 0.0 3.4e-136 453.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase MFS_1_like PF12832.7 AFI85325.1 - 4.7e-99 331.8 29.8 6.2e-99 331.5 29.8 1.1 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 AFI85325.1 - 3.7e-20 72.3 20.2 5.4e-20 71.7 20.2 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1 PF07690.16 AFI85325.1 - 7.6e-18 64.5 48.2 1.8e-12 46.9 24.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily P5-ATPase PF12409.8 AFI85325.1 - 1.6 8.8 7.0 0.39 10.8 0.5 2.6 2 0 0 2 2 2 0 P5-type ATPase cation transporter NQRA PF05896.11 AFI85326.1 - 8.1e-111 369.5 0.0 1.3e-110 368.9 0.0 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NQRA_SLBB PF11973.8 AFI85326.1 - 1.8e-19 70.1 0.3 3.3e-19 69.2 0.3 1.5 1 0 0 1 1 1 1 NQRA C-terminal domain RnfC_N PF13375.6 AFI85326.1 - 0.00027 20.8 0.0 0.00054 19.9 0.0 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQR2_RnfD_RnfE PF03116.15 AFI85327.1 - 1.7e-108 362.4 22.5 2e-108 362.3 22.5 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family FMN_bind PF04205.14 AFI85328.1 - 4.5e-15 56.0 0.0 9.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 FMN-binding domain Rnf-Nqr PF02508.14 AFI85329.1 - 3.4e-60 203.0 13.2 4e-60 202.8 13.2 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein Ints3 PF10189.9 AFI85329.1 - 0.046 13.0 0.4 0.062 12.6 0.4 1.1 1 0 0 1 1 1 0 Integrator complex subunit 3 Rnf-Nqr PF02508.14 AFI85330.1 - 1.9e-60 203.8 12.0 2.1e-60 203.7 12.0 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein Vps54 PF07928.12 AFI85330.1 - 0.15 12.5 0.3 0.22 11.9 0.3 1.3 1 0 0 1 1 1 0 Vps54-like protein NAD_binding_1 PF00175.21 AFI85331.1 - 1.3e-17 64.5 0.0 2.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AFI85331.1 - 6e-12 45.8 0.0 1.5e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 AFI85331.1 - 5.1e-10 39.2 0.3 8.5e-10 38.4 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AFI85331.1 - 0.0062 16.7 0.0 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NqrM PF04400.13 AFI85332.1 - 1.2e-09 37.8 9.4 2.2e-09 36.9 9.4 1.6 1 1 0 1 1 1 1 (Na+)-NQR maturation NqrM Bunya_G2 PF03563.13 AFI85332.1 - 0.0073 15.6 0.0 0.0073 15.6 0.0 1.0 1 0 0 1 1 1 1 Bunyavirus glycoprotein G2 EpuA PF11772.8 AFI85332.1 - 0.075 12.7 3.2 0.099 12.3 3.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta CBS PF00571.28 AFI85333.1 - 1.1e-19 70.6 0.0 4.4e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 CBS domain PALP PF00291.25 AFI85334.1 - 1e-57 195.8 0.1 1.2e-57 195.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PAS_3 PF08447.12 AFI85335.1 - 1e-16 61.0 0.1 1.9e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AFI85335.1 - 1.3e-09 38.0 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AFI85335.1 - 5.9e-09 36.1 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AFI85335.1 - 1.3e-06 28.6 0.0 2.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 AFI85335.1 - 0.0041 17.4 0.0 0.0082 16.4 0.0 1.5 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 AFI85335.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain SpoVT_C PF15714.5 AFI85335.1 - 0.18 11.8 0.0 0.72 9.9 0.0 2.0 3 0 0 3 3 3 0 Stage V sporulation protein T C-terminal, transcription factor GGDEF PF00990.21 AFI85336.1 - 7.8e-36 123.2 0.0 8.7e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain AraC_binding_2 PF14525.6 AFI85339.1 - 1.3e-14 54.3 0.0 1.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 AraC-binding-like domain Cupin_2 PF07883.11 AFI85339.1 - 0.00024 20.7 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_18 PF12833.7 AFI85339.1 - 0.0037 17.5 0.2 0.015 15.6 0.1 2.0 1 1 1 2 2 2 2 Helix-turn-helix domain AraC_binding PF02311.19 AFI85339.1 - 0.062 13.2 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF5381 PF17353.2 AFI85340.1 - 1.8 8.3 4.1 0.66 9.7 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5381) tRNA-synt_1b PF00579.25 AFI85341.1 - 1.8e-78 263.8 0.0 2.3e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AFI85341.1 - 1.2e-08 34.6 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 AFI85341.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4_2 PF13275.6 AFI85341.1 - 0.0016 18.2 0.1 0.0041 16.9 0.1 1.7 1 0 0 1 1 1 1 S4 domain Peptidase_M23 PF01551.22 AFI85342.1 - 3.7e-32 110.4 1.2 9.3e-32 109.1 1.2 1.7 1 0 0 1 1 1 1 Peptidase family M23 OapA PF04225.12 AFI85342.1 - 5.1e-07 29.7 0.8 2.5e-06 27.5 0.1 2.5 3 0 0 3 3 3 1 Opacity-associated protein A LysM-like domain FAP PF07174.11 AFI85342.1 - 0.017 14.6 3.4 0.025 14.0 3.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) AnmK PF03702.14 AFI85343.1 - 2.4e-138 461.2 0.2 2.7e-138 461.0 0.2 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase BcrAD_BadFG PF01869.20 AFI85343.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family GCV_H PF01597.19 AFI85344.1 - 4.5e-38 129.9 0.0 5.2e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Glyco_hydro_77 PF02446.17 AFI85345.1 - 8.4e-144 479.9 5.3 1.2e-143 479.4 5.3 1.2 1 0 0 1 1 1 1 4-alpha-glucanotransferase Glyco_hydro_57 PF03065.15 AFI85346.1 - 3.7e-69 233.4 0.0 4.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 NTP_transferase PF00483.23 AFI85347.1 - 1.8e-65 221.0 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AFI85347.1 - 6.5e-09 36.3 0.0 1.3e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 AFI85347.1 - 0.00022 20.8 4.0 0.1 12.4 0.0 2.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 AFI85347.1 - 0.00063 18.8 0.4 0.0017 17.3 0.1 1.7 2 0 0 2 2 2 1 L-fucokinase CBM_48 PF02922.18 AFI85348.1 - 1.7e-23 82.8 1.5 4.9e-23 81.3 0.0 2.5 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 AFI85348.1 - 1.5e-20 73.4 0.0 3.6e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 AFI85348.1 - 1.8e-17 63.9 0.3 2.6e-11 43.7 0.1 3.0 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 AFI85348.1 - 0.012 15.8 0.1 0.068 13.4 0.0 2.3 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase PGI PF00342.19 AFI85349.1 - 5.3e-230 764.1 0.1 6.1e-230 763.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 AFI85349.1 - 0.11 13.1 0.6 11 6.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) YwpF PF14183.6 AFI85349.1 - 0.14 12.2 0.1 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 YwpF-like protein tRNA-synt_His PF13393.6 AFI85350.1 - 1.2e-49 169.3 0.1 1.5e-49 169.0 0.1 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AFI85350.1 - 7.8e-31 107.4 0.0 1.2e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AFI85350.1 - 1.2e-10 41.4 0.0 5.5e-10 39.3 0.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2 PF00152.20 AFI85350.1 - 0.00084 18.5 0.0 0.055 12.5 0.0 2.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) GcpE PF04551.14 AFI85351.1 - 1.5e-63 215.1 0.1 1.7e-63 214.9 0.1 1.0 1 0 0 1 1 1 1 GcpE protein KH_7 PF17214.3 AFI85351.1 - 0.058 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 KH domain GcpE PF04551.14 AFI85352.1 - 1.9e-51 175.2 0.2 2.3e-51 175.0 0.2 1.0 1 0 0 1 1 1 1 GcpE protein PTE PF02126.18 AFI85352.1 - 0.047 13.1 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family DUF4115 PF13464.6 AFI85353.1 - 1.1e-20 73.5 0.1 1.7e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) DUF5334 PF17268.2 AFI85353.1 - 0.035 14.4 0.2 3.5 8.0 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5334) TPR_2 PF07719.17 AFI85355.1 - 7.9e-24 81.8 10.8 1.1e-06 28.3 0.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 AFI85355.1 - 1.4e-19 69.0 8.1 7.3e-05 22.9 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AFI85355.1 - 2.1e-19 69.9 8.0 1.9e-06 28.4 1.6 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 AFI85355.1 - 9.2e-18 63.2 21.5 2e-05 24.2 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 AFI85355.1 - 5.2e-17 60.6 7.9 9.7e-05 22.3 0.0 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AFI85355.1 - 8.4e-17 61.2 12.4 4.2e-07 30.2 1.6 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AFI85355.1 - 3.2e-16 58.6 4.7 0.0041 17.8 0.0 5.6 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 AFI85355.1 - 1e-15 57.9 10.0 3.6e-05 24.2 0.3 3.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 AFI85355.1 - 1.6e-13 50.6 0.7 0.00028 20.9 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AFI85355.1 - 1.4e-11 43.9 14.3 3.8e-10 39.3 0.3 5.4 2 2 4 6 6 6 1 TPR repeat ANAPC3 PF12895.7 AFI85355.1 - 1.6e-10 41.1 6.2 3.1e-06 27.3 0.2 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AFI85355.1 - 1.8e-10 40.7 11.2 0.0055 17.3 0.1 5.3 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 AFI85355.1 - 1.4e-08 34.3 16.1 0.012 15.4 0.1 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 AFI85355.1 - 3e-08 33.1 7.3 0.015 15.3 0.0 5.4 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 AFI85355.1 - 9.6e-08 32.3 2.1 0.00045 20.5 0.2 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 AFI85355.1 - 5.7e-05 22.5 3.3 0.0008 18.7 1.8 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 AFI85355.1 - 5.8e-05 22.2 0.7 0.0011 17.9 0.1 2.0 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 AFI85355.1 - 0.00062 19.8 3.4 1.5 8.9 0.0 4.1 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat YfiO PF13525.6 AFI85355.1 - 0.0013 18.5 2.9 0.74 9.5 0.3 2.6 1 1 0 2 2 2 2 Outer membrane lipoprotein Coatomer_E PF04733.14 AFI85355.1 - 0.0018 17.8 0.3 0.19 11.1 0.1 2.8 1 1 2 3 3 3 1 Coatomer epsilon subunit DUF4919 PF16266.5 AFI85355.1 - 0.0045 16.9 0.9 0.56 10.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) HrpB1_HrpK PF09613.10 AFI85355.1 - 0.0072 16.0 0.2 0.59 9.8 0.0 2.4 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) HemY_N PF07219.13 AFI85355.1 - 0.0078 16.4 3.1 0.21 11.8 0.1 3.2 2 1 1 3 3 3 1 HemY protein N-terminus Alkyl_sulf_dimr PF14863.6 AFI85355.1 - 0.011 16.2 0.5 0.032 14.7 0.2 1.8 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation PaREP1 PF05942.11 AFI85355.1 - 0.017 15.0 1.3 0.075 13.0 0.4 2.2 2 1 1 3 3 2 0 Archaeal PaREP1/PaREP8 family LPAM_2 PF13627.6 AFI85355.1 - 0.021 14.7 0.5 0.04 13.8 0.5 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ANAPC5 PF12862.7 AFI85355.1 - 0.043 13.9 0.7 0.2 11.8 0.1 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF4810 PF16068.5 AFI85355.1 - 0.056 14.0 4.8 1.6 9.3 0.4 3.6 2 1 2 4 4 3 0 Domain of unknown function (DUF4810) Wzy_C_2 PF11846.8 AFI85355.1 - 0.26 11.2 3.3 0.3 11.0 0.2 2.4 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_3 PF07720.12 AFI85355.1 - 1.2 9.2 4.6 8.7 6.5 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat ATP-synt_DE PF00401.20 AFI85355.1 - 4.9 7.5 7.9 16 5.8 0.2 3.3 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Radical_SAM PF04055.21 AFI85356.1 - 2.5e-18 67.0 0.0 4.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AFI85356.1 - 0.003 17.7 0.0 0.0074 16.4 0.0 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain DUF3966 PF13110.6 AFI85356.1 - 0.02 14.8 0.2 2.6 8.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3966) Phage_sheath_1C PF17482.2 AFI85356.1 - 0.16 11.9 0.1 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain NDK PF00334.19 AFI85357.1 - 1.1e-58 197.1 0.0 1.2e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NAD_kinase PF01513.21 AFI85359.1 - 1.9e-55 188.2 0.3 2.4e-55 187.8 0.3 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AFI85359.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Peripla_BP_1 PF00532.21 AFI85359.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family SMC_N PF02463.19 AFI85360.1 - 2.5e-20 72.9 0.0 7.2e-20 71.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AFI85360.1 - 8.9e-11 42.7 18.2 2.6e-09 37.9 18.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI85360.1 - 1.9e-05 24.3 0.5 4.7e-05 23.0 0.5 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AFI85360.1 - 0.0065 16.3 0.3 0.79 9.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system HTH_23 PF13384.6 AFI85360.1 - 0.0072 16.1 0.2 0.34 10.8 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_18 PF12833.7 AFI85360.1 - 0.035 14.4 0.7 2.8 8.3 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain NTPase_P4 PF11602.8 AFI85360.1 - 0.069 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 RsgA_GTPase PF03193.16 AFI85360.1 - 0.071 13.0 1.6 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase HTH_17 PF12728.7 AFI85360.1 - 0.11 12.7 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1799 PF08809.11 AFI85360.1 - 0.15 12.3 0.3 2 8.6 0.0 2.6 3 0 0 3 3 2 0 Phage related hypothetical protein (DUF1799) AAA_22 PF13401.6 AFI85360.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.4 2 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 AFI85360.1 - 0.44 11.1 12.9 15 6.1 9.5 3.8 2 1 1 3 3 3 0 ABC transporter Noelin-1 PF12308.8 AFI85360.1 - 4.9 7.2 7.2 1.4 8.9 1.5 2.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein BLOC1_2 PF10046.9 AFI85360.1 - 5.8 7.3 14.5 5.2 7.4 3.1 3.8 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4558 PF15104.6 AFI85360.1 - 6.5 6.9 16.8 0.71 10.0 7.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4558) FUR PF01475.19 AFI85361.1 - 2.3e-45 153.6 0.1 2.6e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 AFI85361.1 - 0.023 14.7 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MarR PF01047.22 AFI85361.1 - 0.024 14.5 0.1 0.092 12.7 0.1 2.0 1 1 0 1 1 1 0 MarR family HTH_Tnp_Tc3_2 PF01498.18 AFI85361.1 - 0.03 14.5 0.0 1.1 9.6 0.0 2.2 1 1 1 2 2 2 0 Transposase TrmB PF01978.19 AFI85361.1 - 0.031 14.2 0.2 1.2 9.1 0.0 2.6 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 AFI85361.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 Transcriptional regulator PadR-like family SR1P PF13790.6 AFI85361.1 - 0.13 12.4 3.3 2.5 8.3 0.2 2.3 2 0 0 2 2 2 0 SR1 protein SmpA_OmlA PF04355.13 AFI85362.1 - 7.4e-26 89.7 0.1 1.1e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 SmpA / OmlA family DUF5110 PF17137.4 AFI85362.1 - 0.0099 16.1 3.0 0.13 12.6 0.4 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF5110) PMM PF03332.13 AFI85362.1 - 0.015 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase PAS_11 PF14598.6 AFI85362.1 - 0.037 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 PAS domain Pro_CA PF00484.19 AFI85363.1 - 3e-52 177.0 0.0 3.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Lactamase_B PF00753.27 AFI85364.1 - 1.5e-28 100.2 1.0 1.7e-28 100.0 1.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AFI85364.1 - 3.3e-05 23.5 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 AFI85364.1 - 0.024 13.8 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Lactamase_B_3 PF13483.6 AFI85364.1 - 0.034 14.0 0.0 0.057 13.3 0.0 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AFI85364.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain HAGH_C PF16123.5 AFI85364.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Picorna_P3A PF06363.11 AFI85365.1 - 0.019 14.8 1.3 8.9 6.3 0.1 3.4 4 0 0 4 4 4 0 Picornaviridae P3A protein DUF3269 PF11673.8 AFI85365.1 - 0.024 15.0 0.0 5.5 7.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3269) AAA_32 PF13654.6 AFI85367.1 - 2.1e-177 591.0 2.9 2.6e-177 590.7 2.9 1.1 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 AFI85367.1 - 1.2e-09 38.0 0.0 2.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Sigma54_activ_2 PF14532.6 AFI85367.1 - 0.00021 21.4 0.0 0.0012 19.0 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 AFI85367.1 - 0.0048 17.3 0.1 0.012 16.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AFI85367.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AFI85367.1 - 0.034 13.5 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2226 PF09987.9 AFI85367.1 - 0.14 11.4 0.9 0.37 10.1 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) PilZ PF07238.14 AFI85368.1 - 1.3e-13 51.2 0.0 1.5e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 PilZ domain Pterin_bind PF00809.22 AFI85368.1 - 0.04 13.6 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 Pterin binding enzyme COQ7 PF03232.13 AFI85369.1 - 6.8e-43 146.4 1.1 8.4e-43 146.1 1.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 AFI85369.1 - 3e-07 30.9 0.3 6.1e-07 29.9 0.3 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 AFI85369.1 - 0.0053 16.7 1.4 0.015 15.2 1.4 1.7 1 1 0 1 1 1 1 Ferritin-like domain RyR PF02026.16 AFI85369.1 - 0.16 12.1 0.7 0.94 9.7 0.1 2.3 2 0 0 2 2 2 0 RyR domain TTRAP PF14203.6 AFI85369.1 - 0.25 11.4 0.9 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein GGDEF PF00990.21 AFI85370.1 - 9.5e-37 126.2 0.5 6.8e-35 120.2 0.5 2.4 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GCV_T PF01571.21 AFI85370.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Stealth_CR4 PF17103.5 AFI85370.1 - 0.1 12.5 0.1 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Stealth protein CR4, conserved region 4 GGDEF_2 PF17853.1 AFI85370.1 - 0.12 12.6 0.1 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 GGDEF-like domain CheW PF01584.19 AFI85371.1 - 5.5e-34 116.8 0.1 8.3e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AFI85371.1 - 2.1e-14 53.6 0.3 1.1e-13 51.3 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain DUF512 PF04459.12 AFI85371.1 - 0.087 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) RNB PF00773.19 AFI85372.1 - 4.6e-111 371.3 0.0 2.9e-110 368.6 0.0 1.9 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.11 AFI85372.1 - 2.7e-26 91.0 1.3 2.8e-22 78.1 0.3 2.7 2 0 0 2 2 2 2 Ribonuclease B OB domain CSD2 PF17876.1 AFI85372.1 - 4.9e-26 90.7 0.1 1.3e-23 82.9 0.1 2.7 2 0 0 2 2 2 1 Cold shock domain S1 PF00575.23 AFI85372.1 - 1.4e-13 50.9 3.5 2.4e-13 50.2 0.7 2.7 3 0 0 3 3 3 1 S1 RNA binding domain HTH_12 PF08461.10 AFI85372.1 - 1.5e-10 40.8 1.2 3.6e-10 39.6 1.2 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain OB_Dis3 PF17849.1 AFI85372.1 - 0.00014 21.8 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) RNase_II_C_S1 PF18614.1 AFI85372.1 - 0.052 13.5 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain MCPsignal PF00015.21 AFI85373.1 - 8.2e-44 149.4 30.3 2.9e-43 147.7 20.4 2.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AFI85373.1 - 2.1e-13 50.3 0.1 4.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AFI85373.1 - 1.5e-09 38.0 0.3 5.2e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AFI85373.1 - 2.1e-07 30.9 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI85373.1 - 0.00016 21.9 0.0 0.00058 20.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold APG17 PF04108.12 AFI85373.1 - 0.0034 16.6 2.0 0.0034 16.6 2.0 2.5 1 1 0 2 2 2 1 Autophagy protein Apg17 Fib_alpha PF08702.10 AFI85373.1 - 0.0094 16.1 17.5 0.32 11.2 4.3 2.8 2 1 1 3 3 3 3 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 AFI85373.1 - 0.036 14.3 14.2 0.033 14.5 2.0 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4559 PF15112.6 AFI85373.1 - 0.46 10.1 13.0 0.27 10.9 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) WXG100 PF06013.12 AFI85373.1 - 0.57 10.5 11.1 0.043 14.1 2.5 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG AIP3 PF03915.13 AFI85373.1 - 1.5 7.8 13.5 2.7 7.0 6.9 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 DUF2533 PF10752.9 AFI85373.1 - 3.7 8.1 8.9 0.92 10.0 0.3 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF2533) Nup54 PF13874.6 AFI85373.1 - 6.8 6.8 13.9 5.8 7.0 3.5 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 ELFV_dehydrog PF00208.21 AFI85374.1 - 2.5e-78 263.2 0.0 3.3e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 AFI85374.1 - 1.8e-51 173.4 0.0 3.9e-51 172.3 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 AFI85374.1 - 0.0023 18.3 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding PQQ PF01011.21 AFI85377.1 - 1.2e-33 113.4 8.8 6.3e-05 22.7 0.0 7.1 7 0 0 7 7 7 6 PQQ enzyme repeat PQQ_2 PF13360.6 AFI85377.1 - 1.2e-29 103.6 6.3 2.3e-12 47.0 0.1 4.4 3 2 0 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AFI85377.1 - 1.5e-21 76.2 21.3 3.1e-07 30.7 0.0 7.9 9 0 0 9 9 9 5 PQQ-like domain Isochorismatase PF00857.20 AFI85378.1 - 1e-36 126.7 0.1 1.4e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Catalase PF00199.19 AFI85379.1 - 4.8e-30 104.9 0.0 5.7e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Catalase TetR_C_13 PF16925.5 AFI85380.1 - 7.9e-36 122.5 0.1 1.1e-35 122.0 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AFI85380.1 - 7.3e-11 41.7 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AFI85380.1 - 4.6e-05 23.7 0.0 7.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 AFI85380.1 - 0.0021 18.1 0.1 0.0088 16.1 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 AFI85380.1 - 0.0043 17.2 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_6 PF13977.6 AFI85380.1 - 0.0048 17.1 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal HAD_2 PF13419.6 AFI85380.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TetR_C_37 PF18665.1 AFI85380.1 - 0.093 13.4 0.3 0.24 12.0 0.0 1.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TetR PF13972.6 AFI85380.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor XFP PF03894.15 AFI85380.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase ADH_zinc_N PF00107.26 AFI85381.1 - 9.3e-19 67.7 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AFI85381.1 - 7e-18 66.0 0.0 1.3e-17 65.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AFI85381.1 - 6.6e-11 42.1 0.0 7.3e-10 38.7 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SGL PF08450.12 AFI85382.1 - 1.1e-21 77.6 11.9 4e-10 39.7 2.3 3.6 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 AFI85382.1 - 2.6e-21 76.3 0.2 6.2e-20 71.8 0.0 2.8 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 AFI85382.1 - 3.1e-07 30.1 6.9 0.25 11.4 0.0 7.0 7 0 0 7 7 7 2 NHL repeat Str_synth PF03088.16 AFI85382.1 - 1.5e-06 28.3 0.2 0.99 9.6 0.0 5.4 5 0 0 5 5 5 1 Strictosidine synthase DUF5050 PF16472.5 AFI85382.1 - 0.00046 19.5 0.1 0.019 14.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5050) Lactonase PF10282.9 AFI85382.1 - 0.14 11.4 0.0 4.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Flagellin_D3 PF08884.11 AFI85382.1 - 0.3 11.5 6.5 0.31 11.5 1.5 3.4 3 1 0 3 3 3 0 Flagellin D3 domain Me-amine-dh_H PF06433.11 AFI85383.1 - 0.11 11.3 0.2 1 8.1 0.0 1.9 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Me-amine-dh_H PF06433.11 AFI85384.1 - 0.084 11.7 0.8 8.7 5.1 0.0 3.6 3 2 2 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) Defensin_beta PF00711.19 AFI85385.1 - 0.15 12.1 4.2 3.8 7.6 0.1 3.0 4 0 0 4 4 4 0 Beta defensin Me-amine-dh_H PF06433.11 AFI85387.1 - 0.036 12.9 0.0 0.51 9.1 0.0 1.9 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Me-amine-dh_H PF06433.11 AFI85389.1 - 0.11 11.3 0.2 1 8.1 0.0 1.9 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Me-amine-dh_H PF06433.11 AFI85391.1 - 0.0049 15.8 0.8 6 5.6 0.0 3.9 1 1 3 4 4 4 3 Methylamine dehydrogenase heavy chain (MADH) TIG_plexin PF17960.1 AFI85391.1 - 0.01 15.8 0.2 0.019 15.0 0.1 1.6 1 1 0 1 1 1 0 TIG domain Me-amine-dh_H PF06433.11 AFI85392.1 - 0.56 9.0 3.4 21 3.8 0.2 3.8 1 1 4 5 5 5 0 Methylamine dehydrogenase heavy chain (MADH) Y_phosphatase PF00102.27 AFI85392.1 - 0.73 9.3 2.8 0.84 9.1 0.6 2.0 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Peptidase_S13 PF02113.15 AFI85393.1 - 0.0039 16.0 0.0 1 8.0 0.0 2.7 2 1 1 3 3 3 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF3021 PF11457.8 AFI85394.1 - 0.042 14.2 3.6 0.16 12.3 1.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3021) eIF3_p135 PF12807.7 AFI85394.1 - 0.11 12.5 11.3 4.9 7.2 0.1 5.3 2 2 2 5 5 5 0 Translation initiation factor eIF3 subunit 135 ABC2_membrane_3 PF12698.7 AFI85394.1 - 3 6.9 4.6 4.4 6.3 4.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4325 PF14213.6 AFI85394.1 - 5 6.9 8.9 2.9 7.7 0.0 4.5 5 2 2 7 7 7 0 STAS-like domain of unknown function (DUF4325) HOK_GEF PF01848.16 AFI85397.1 - 0.024 14.1 0.3 2.2 7.7 0.2 2.8 2 1 1 3 3 3 0 Hok/gef family FNIP_N PF14636.6 AFI85398.1 - 0.053 14.5 1.5 0.63 11.0 0.0 2.0 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus Cas_Csy4 PF09618.10 AFI85399.1 - 4.8e-58 196.3 0.0 5.3e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy4) MecA_N PF05223.11 AFI85401.1 - 0.12 12.6 0.4 0.64 10.3 0.0 2.2 2 1 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain ResIII PF04851.15 AFI85402.1 - 2.9e-10 40.4 0.1 1.5e-09 38.1 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HD_6 PF18019.1 AFI85402.1 - 3.4e-10 40.4 0.1 1.1e-09 38.7 0.1 1.9 1 0 0 1 1 1 1 HD domain DEAD PF00270.29 AFI85402.1 - 1.9e-06 27.8 0.0 4.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HD PF01966.22 AFI85402.1 - 7e-05 23.0 0.3 0.0008 19.6 0.2 2.7 2 0 0 2 2 2 1 HD domain PhoH PF02562.16 AFI85402.1 - 0.0045 16.5 0.0 0.018 14.5 0.0 2.0 1 0 0 1 1 1 1 PhoH-like protein HDOD PF08668.12 AFI85402.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 HDOD domain AAA_22 PF13401.6 AFI85402.1 - 0.02 15.2 0.2 0.18 12.1 0.1 2.7 2 1 0 2 2 1 0 AAA domain SNF2_N PF00176.23 AFI85402.1 - 0.026 13.3 0.4 0.062 12.0 0.0 1.7 2 0 0 2 2 2 0 SNF2 family N-terminal domain UPF0122 PF04297.14 AFI85402.1 - 0.047 13.9 0.7 0.15 12.3 0.7 1.9 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Arm-DNA-bind_4 PF14657.6 AFI85402.1 - 0.066 13.0 0.0 0.3 10.9 0.0 2.2 1 0 0 1 1 1 0 Arm DNA-binding domain AAA_11 PF13086.6 AFI85402.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AFI85402.1 - 0.13 12.6 0.0 0.49 10.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AFI85402.1 - 0.13 12.1 0.1 5.1 7.0 0.0 3.2 3 0 0 3 3 3 0 NACHT domain Cas_Cas1 PF01867.16 AFI85403.1 - 3.2e-13 49.4 0.0 4.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein Cas1 T3SS_needle_E PF08988.10 AFI85403.1 - 0.034 14.3 0.2 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle WYL PF13280.6 AFI85404.1 - 3.4e-36 124.9 0.6 5e-36 124.3 0.6 1.2 1 0 0 1 1 1 1 WYL domain Pkinase PF00069.25 AFI85405.1 - 1.1e-39 136.4 0.0 1.5e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AFI85405.1 - 1.7e-20 73.4 0.0 3.4e-20 72.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PP2C PF00481.21 AFI85405.1 - 9.8e-15 54.9 0.2 9.5e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 AFI85405.1 - 1.2e-13 51.2 0.2 2.3e-13 50.3 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C APH PF01636.23 AFI85405.1 - 4.9e-07 29.9 0.2 0.008 16.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family SpoIIE PF07228.12 AFI85405.1 - 8.6e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Kinase-like PF14531.6 AFI85405.1 - 0.00022 20.7 0.0 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 AFI85405.1 - 0.005 16.4 0.0 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 AFI85405.1 - 0.0059 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 AFI85405.1 - 0.024 13.6 0.0 0.2 10.6 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 AFI85405.1 - 0.037 12.8 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 AFI85405.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 AFI85405.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MFS_1 PF07690.16 AFI85406.1 - 1e-36 126.7 56.9 2.3e-22 79.4 26.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AFI85406.1 - 5.6e-07 28.8 33.5 0.00021 20.3 8.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter EAL PF00563.20 AFI85408.1 - 5.4e-45 153.8 0.0 8.6e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 EAL domain YkuI_C PF10388.9 AFI85408.1 - 0.0049 16.7 0.6 0.0078 16.0 0.6 1.3 1 0 0 1 1 1 1 EAL-domain associated signalling protein domain Arc_trans_TRASH PF08394.10 AFI85408.1 - 0.11 12.8 0.9 0.22 11.9 0.9 1.4 1 0 0 1 1 1 0 Archaeal TRASH domain Molybdopterin PF00384.22 AFI85409.1 - 7.2e-78 262.5 0.0 3e-77 260.4 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AFI85409.1 - 4.5e-26 91.0 0.2 1.4e-25 89.5 0.1 1.9 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AFI85409.1 - 1.9e-18 66.2 0.8 5.1e-18 64.8 0.7 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 AFI85409.1 - 3.6e-15 56.0 2.8 9.9e-15 54.6 2.8 1.8 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 AFI85410.1 - 3.2e-15 56.0 0.0 3.5e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 AFI85410.1 - 3.7e-14 52.4 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.14 AFI85411.1 - 5.4e-53 180.1 0.3 1e-52 179.2 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AFI85411.1 - 7.4e-30 103.1 4.7 4e-14 52.7 0.1 2.9 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 AFI85411.1 - 5.1e-28 97.6 0.2 8.2e-28 96.9 0.2 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rubredoxin_C PF18267.1 AFI85411.1 - 1.1e-19 70.1 0.1 4.3e-19 68.2 0.1 2.1 2 0 0 2 2 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 AFI85411.1 - 2.5e-16 60.0 3.1 1.3e-15 57.7 0.3 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 AFI85411.1 - 2.9e-15 55.9 0.0 5.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 AFI85411.1 - 5.6e-12 45.5 0.0 1.4e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AFI85411.1 - 5.5e-05 23.2 1.7 0.15 12.1 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 AFI85411.1 - 0.0021 18.5 0.1 0.05 14.1 0.1 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 AFI85411.1 - 0.02 14.8 0.4 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AFI85411.1 - 0.021 14.4 1.5 33 3.9 1.6 3.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AFI85411.1 - 0.036 13.4 1.3 0.077 12.3 0.3 2.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AFI85411.1 - 0.073 12.3 0.2 0.21 10.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DGC PF08859.11 AFI85411.1 - 0.13 12.4 1.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 DGC domain Lycopene_cycl PF05834.12 AFI85411.1 - 0.16 11.0 3.2 1 8.4 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 AFI85411.1 - 0.31 10.1 3.0 1.6 7.7 0.9 2.4 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AFI85411.1 - 0.77 8.8 3.3 1.8 7.5 1.3 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 AFI85411.1 - 1.1 7.8 6.0 29 3.2 0.1 3.4 3 1 1 4 4 4 0 HI0933-like protein GGDEF PF00990.21 AFI85412.1 - 2.1e-45 154.4 0.6 4.3e-45 153.4 0.6 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AFI85412.1 - 3.2e-13 50.0 6.5 4.6e-13 49.5 6.5 1.2 1 0 0 1 1 1 1 Cache domain GGDEF_2 PF17853.1 AFI85412.1 - 5.6e-05 23.4 0.1 0.00095 19.4 0.0 2.6 3 0 0 3 3 3 1 GGDEF-like domain Cas_APE2256 PF09651.10 AFI85412.1 - 0.016 15.1 0.2 0.085 12.7 0.1 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) GPW_gp25 PF04965.14 AFI85412.1 - 0.026 14.3 0.1 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 Gene 25-like lysozyme EAL PF00563.20 AFI85413.1 - 6.6e-64 215.7 0.3 1.4e-63 214.6 0.3 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI85413.1 - 2.5e-48 163.9 0.7 7.2e-48 162.4 0.2 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AFI85413.1 - 3.3e-13 49.8 0.1 8.7e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AFI85413.1 - 1.8e-10 40.8 0.0 4.8e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI85413.1 - 4.3e-07 29.8 0.0 2.2e-06 27.6 0.0 2.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AFI85413.1 - 0.00016 21.9 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI85413.1 - 0.0031 17.7 0.0 0.0076 16.5 0.0 1.7 1 1 0 1 1 1 1 PAS fold DUF4440 PF14534.6 AFI85414.1 - 7e-12 45.7 0.0 8.5e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AFI85414.1 - 9.9e-08 32.6 0.0 1.3e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 AFI85414.1 - 1.6e-07 31.6 0.4 2.3e-07 31.1 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 AFI85414.1 - 2.2e-07 31.5 0.0 2.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3225 PF11533.8 AFI85414.1 - 0.0089 15.7 0.0 0.011 15.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL_4 PF13577.6 AFI85414.1 - 0.024 14.8 0.0 0.034 14.3 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain CaMKII_AD PF08332.10 AFI85414.1 - 0.059 13.5 0.2 0.15 12.2 0.2 1.8 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Lum_binding PF00677.17 AFI85414.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Lumazine binding domain MarR PF01047.22 AFI85415.1 - 3.2e-09 36.6 0.2 6.4e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AFI85415.1 - 2e-07 30.8 0.3 3.1e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AFI85415.1 - 8.1e-05 23.0 0.1 0.0002 21.8 0.2 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AFI85415.1 - 0.0022 17.8 0.9 0.0055 16.5 0.9 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AFI85415.1 - 0.0073 16.2 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AFI85415.1 - 0.023 14.7 0.8 0.023 14.7 0.8 1.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AFI85415.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_26 PF13443.6 AFI85415.1 - 0.096 13.1 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain GGDEF PF00990.21 AFI85416.1 - 7e-45 152.7 0.2 1.6e-44 151.5 0.2 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 AFI85416.1 - 2.8e-18 66.6 0.3 1e-16 61.5 0.1 2.5 2 0 0 2 2 2 1 Cache domain PAS_4 PF08448.10 AFI85416.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold ABC_membrane_3 PF13748.6 AFI85416.1 - 0.69 9.1 4.9 0.13 11.5 0.6 1.9 3 0 0 3 3 3 0 ABC transporter transmembrane region STE3 PF02076.15 AFI85416.1 - 1.2 8.3 6.3 1.7 7.8 0.6 2.7 3 0 0 3 3 3 0 Pheromone A receptor Gram_pos_anchor PF00746.21 AFI85416.1 - 3.4 7.7 7.7 3.9 7.5 0.3 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF4381 PF14316.6 AFI85416.1 - 7 6.9 7.1 12 6.1 2.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF463 PF04317.12 AFI85417.1 - 1.5e-130 436.1 0.0 1.7e-130 435.9 0.0 1.0 1 0 0 1 1 1 1 YcjX-like family, DUF463 KAP_NTPase PF07693.14 AFI85417.1 - 0.0012 18.2 0.0 0.0027 17.0 0.0 1.6 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 AFI85417.1 - 0.0016 18.7 0.0 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 AFI85417.1 - 0.0019 17.2 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 AFI85417.1 - 0.0091 16.5 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NTPase_1 PF03266.15 AFI85417.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 AFI85417.1 - 0.014 15.8 0.1 0.049 14.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 AFI85417.1 - 0.019 14.0 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 AFI85417.1 - 0.022 14.5 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 AFI85417.1 - 0.023 14.3 0.4 0.073 12.7 0.2 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 AFI85417.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 AFI85417.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DUF87 PF01935.17 AFI85417.1 - 0.061 13.4 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 AFI85417.1 - 0.062 13.4 0.1 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 AFI85417.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 AFI85417.1 - 0.084 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 AFI85417.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFI85417.1 - 0.13 12.8 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AFI85417.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 AFI85417.1 - 0.16 11.7 0.3 0.29 10.8 0.3 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF697 PF05128.12 AFI85418.1 - 4.1e-27 94.9 0.4 4.1e-27 94.9 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF697) SCAMP PF04144.13 AFI85418.1 - 0.0045 17.3 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 SCAMP family DctQ PF04290.12 AFI85418.1 - 0.029 14.3 1.5 0.065 13.1 1.5 1.5 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component CcmD PF04995.14 AFI85418.1 - 0.062 13.4 0.7 0.062 13.4 0.7 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF4131 PF13567.6 AFI85418.1 - 0.62 9.7 3.5 0.58 9.8 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GGDEF PF00990.21 AFI85419.1 - 1.7e-51 174.1 0.0 4.6e-51 172.8 0.0 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE PF03924.13 AFI85419.1 - 1.6e-49 168.4 0.0 2.9e-49 167.6 0.0 1.5 1 0 0 1 1 1 1 CHASE domain PAS_3 PF08447.12 AFI85419.1 - 2.7e-47 159.0 0.1 6e-21 74.5 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 AFI85419.1 - 2.6e-26 91.8 1.2 2.1e-15 56.7 0.1 3.6 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AFI85419.1 - 5e-23 81.3 0.1 8.2e-13 48.5 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 AFI85419.1 - 3.4e-19 69.1 0.1 8.1e-11 42.2 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 AFI85419.1 - 4.4e-11 42.5 0.5 6.2e-07 29.3 0.1 3.4 3 0 0 3 3 3 2 PAS domain Guanylate_cyc PF00211.20 AFI85419.1 - 0.0036 16.9 0.0 0.0092 15.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FtsX PF02687.21 AFI85419.1 - 0.11 13.0 2.1 1.2 9.6 0.3 2.5 2 0 0 2 2 2 0 FtsX-like permease family Baculo_11_kDa PF06143.11 AFI85419.1 - 0.15 11.6 2.1 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family Amnionless PF14828.6 AFI85420.1 - 0.014 14.3 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless Peptidase_C39_2 PF13529.6 AFI85421.1 - 4e-13 50.1 1.8 2.5e-12 47.6 0.1 2.8 2 2 0 2 2 2 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 AFI85421.1 - 1.1e-07 31.9 0.2 2.6e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 AFI85421.1 - 2.4e-07 30.6 0.0 4.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family TPR_14 PF13428.6 AFI85421.1 - 0.00034 21.2 2.1 0.16 12.9 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AFI85421.1 - 0.00054 20.4 2.1 0.0011 19.5 2.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AFI85421.1 - 0.00066 19.4 3.6 0.13 12.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AFI85421.1 - 0.00069 19.5 4.0 0.58 10.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AFI85421.1 - 0.0043 17.7 3.0 0.0065 17.1 0.4 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AFI85421.1 - 0.009 16.3 0.1 0.009 16.3 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 AFI85421.1 - 0.41 11.0 6.1 3.3 8.1 2.9 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AFI85421.1 - 0.5 10.7 1.9 58 4.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Arnt_C PF18583.1 AFI85421.1 - 0.73 9.5 3.4 0.53 9.9 0.6 2.0 1 1 1 2 2 2 0 Aminoarabinose transferase C-terminal domain EAL PF00563.20 AFI85422.1 - 2.1e-47 161.6 0.1 2.7e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 EAL domain Copper-bind PF00127.20 AFI85423.1 - 9.1e-19 67.7 0.1 1.1e-18 67.5 0.1 1.1 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family EutQ PF06249.12 AFI85423.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 Ethanolamine utilisation protein EutQ DUF4032 PF13224.6 AFI85424.1 - 0.026 14.4 2.6 0.69 9.8 1.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4032) PepSY_2 PF13670.6 AFI85424.1 - 0.049 13.6 0.9 0.2 11.6 0.1 2.4 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Rootletin PF15035.6 AFI85426.1 - 0.00061 19.9 1.1 0.00084 19.4 1.1 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Peripla_BP_2 PF01497.18 AFI85426.1 - 0.016 14.8 0.7 0.024 14.2 0.7 1.2 1 0 0 1 1 1 0 Periplasmic binding protein UPF0242 PF06785.11 AFI85426.1 - 0.032 14.4 0.7 0.05 13.7 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 AFI85426.1 - 0.042 13.9 3.3 0.066 13.2 3.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.9 AFI85426.1 - 0.055 13.8 6.2 0.095 13.0 6.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein GAS PF13851.6 AFI85426.1 - 0.059 12.7 3.2 0.089 12.1 3.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DDE_Tnp_1_3 PF13612.6 AFI85427.1 - 4.1e-11 43.1 0.1 5.4e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85427.1 - 2.1e-05 24.3 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain FixQ PF05545.11 AFI85427.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CDP-OH_P_transf PF01066.21 AFI85428.1 - 4e-17 62.8 0.6 4e-17 62.8 0.6 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UvrC_HhH_N PF08459.11 AFI85429.1 - 9e-55 184.8 0.0 2.2e-54 183.6 0.0 1.7 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AFI85429.1 - 4.9e-12 45.9 0.0 1.4e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 AFI85429.1 - 7.6e-10 38.2 0.9 6.4e-09 35.3 0.6 2.5 2 0 0 2 2 2 1 UvrB/uvrC motif HHH_5 PF14520.6 AFI85429.1 - 2.2e-07 31.4 0.1 4.7e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 AFI85429.1 - 5.7e-07 29.5 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AFI85429.1 - 0.0011 19.2 0.2 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 AFI85429.1 - 0.0016 18.2 0.0 0.097 12.6 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif Lzipper-MIP1 PF14389.6 AFI85429.1 - 0.33 11.3 5.2 0.45 10.8 0.0 3.1 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TRCF PF03461.15 AFI85431.1 - 1.8e-28 98.8 0.7 1.8e-27 95.6 0.0 2.9 4 0 0 4 4 4 1 TRCF domain CarD_CdnL_TRCF PF02559.16 AFI85431.1 - 1e-26 93.5 0.0 4e-26 91.6 0.0 2.1 1 0 0 1 1 1 1 CarD-like/TRCF domain UvrB_inter PF17757.1 AFI85431.1 - 4e-23 81.4 0.1 1.1e-22 79.9 0.1 1.9 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 AFI85431.1 - 1.3e-20 73.9 0.1 3.1e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI85431.1 - 1.2e-16 61.1 0.5 6.6e-15 55.4 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AFI85431.1 - 5.4e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UB2H PF14814.6 AFI85431.1 - 0.0023 17.9 0.1 0.022 14.8 0.0 2.7 3 0 0 3 3 3 1 Bifunctional transglycosylase second domain Glyco_tran_WecB PF03808.13 AFI85431.1 - 0.12 12.3 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Methyltransf_11 PF08241.12 AFI85432.1 - 1.7e-18 67.0 0.0 4.3e-18 65.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI85432.1 - 2.2e-17 63.6 0.0 4.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI85432.1 - 1e-16 61.1 0.0 1.8e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85432.1 - 6.1e-14 52.6 0.0 1.1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI85432.1 - 9.9e-14 51.5 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AFI85432.1 - 4.4e-08 32.9 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AFI85432.1 - 2.3e-06 27.4 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 AFI85432.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 AFI85432.1 - 3.3e-05 23.4 0.0 0.047 13.2 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 AFI85432.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 AFI85432.1 - 0.00046 19.8 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 AFI85432.1 - 0.00048 19.1 0.0 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 AFI85432.1 - 0.00071 19.0 0.0 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 AFI85432.1 - 0.00099 19.1 0.0 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 AFI85432.1 - 0.0025 17.5 0.1 0.0036 17.0 0.1 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DREV PF05219.12 AFI85432.1 - 0.0027 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 AFI85432.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.5 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 AFI85432.1 - 0.017 16.1 0.0 0.04 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 AFI85432.1 - 0.046 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sec2p PF06428.11 AFI85432.1 - 0.097 12.7 0.8 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AviRa PF11599.8 AFI85432.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa 3HCDH_N PF02737.18 AFI85432.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_protease PF05618.11 AFI85433.1 - 1.5e-40 138.2 1.0 3.1e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Putative ATP-dependant zinc protease MnmE_helical PF12631.7 AFI85433.1 - 0.014 15.5 0.2 0.014 15.5 0.2 1.2 1 0 0 1 1 1 0 MnmE helical domain DUF5364 PF17322.2 AFI85433.1 - 0.017 15.4 4.5 0.036 14.4 4.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5364) gag-asp_proteas PF13975.6 AFI85433.1 - 0.02 15.4 1.6 0.42 11.2 0.1 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease COG5 PF10392.9 AFI85433.1 - 0.079 13.1 4.9 0.16 12.1 4.9 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TetR_C_24 PF17932.1 AFI85433.1 - 0.1 12.8 1.1 0.2 12.0 1.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2968 PF11180.8 AFI85433.1 - 0.2 11.2 11.3 0.34 10.5 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) 7TM_transglut PF14402.6 AFI85434.1 - 5.3e-108 360.2 23.3 7e-108 359.8 23.3 1.1 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase Transglut_i_TM PF14400.6 AFI85434.1 - 9.3e-53 178.6 0.4 1.4e-52 178.0 0.4 1.3 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices ATPgrasp_ST PF14397.6 AFI85435.1 - 2.4e-114 381.4 0.0 2.8e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 AFI85435.1 - 1.8e-08 34.0 0.0 0.00031 20.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.11 AFI85435.1 - 2.8e-08 33.6 0.0 0.0028 17.3 0.0 3.0 2 1 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 AFI85435.1 - 1e-06 28.9 0.0 0.056 13.5 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp domain GSH-S_ATP PF02955.16 AFI85435.1 - 0.00011 21.6 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.15 AFI85435.1 - 0.046 12.8 0.0 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATPgrasp_TupA PF14305.6 AFI85435.1 - 0.081 12.7 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp Dala_Dala_lig_C PF07478.13 AFI85435.1 - 0.099 12.2 0.0 0.81 9.2 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 AFI85435.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain SIMPL PF04402.14 AFI85436.1 - 1.9e-18 67.6 0.9 2.2e-18 67.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Radical_SAM PF04055.21 AFI85437.1 - 9e-16 58.7 0.0 1.4e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF4917 PF16263.5 AFI85437.1 - 0.0017 17.7 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4917) DUF1848 PF08902.11 AFI85437.1 - 0.014 15.2 2.7 0.019 14.7 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) GFO_IDH_MocA PF01408.22 AFI85438.1 - 6.8e-23 81.8 0.7 4.2e-22 79.2 0.3 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AFI85438.1 - 1.7e-09 37.7 0.0 6.3e-08 32.6 0.0 2.3 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 AFI85438.1 - 0.00028 21.5 0.9 0.00051 20.7 0.9 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Redoxin PF08534.10 AFI85439.1 - 1.5e-31 109.1 0.0 1.8e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AFI85439.1 - 2.2e-09 37.3 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Rib_5-P_isom_A PF06026.14 AFI85440.1 - 9e-48 162.1 0.9 1.3e-47 161.6 0.9 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AFI85440.1 - 7e-09 35.8 0.7 1.9e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 DeoR C terminal sensor domain Fructosamin_kin PF03881.14 AFI85441.1 - 1.5e-104 349.3 0.0 1.7e-104 349.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 AFI85441.1 - 2.4e-14 53.9 0.0 4.3e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family LMWPc PF01451.21 AFI85442.1 - 3.2e-43 147.5 0.0 3.6e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CitMHS PF03600.16 AFI85443.1 - 2.7e-52 177.9 27.5 2.7e-52 177.9 27.5 1.9 2 1 1 3 3 3 1 Citrate transporter DUF4491 PF14898.6 AFI85443.1 - 0.024 15.1 0.6 0.024 15.1 0.6 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4491) DAHP_synth_1 PF00793.20 AFI85444.1 - 1.7e-98 328.8 0.0 2.1e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Rnf-Nqr PF02508.14 AFI85445.1 - 1.5e-61 207.4 20.8 1.6e-61 207.3 20.8 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein YqzM PF14141.6 AFI85445.1 - 2.9 8.0 6.3 20 5.4 0.1 2.5 2 0 0 2 2 2 0 YqzM-like protein Fer4_21 PF14697.6 AFI85446.1 - 3e-18 65.7 16.8 3e-18 65.7 16.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 AFI85446.1 - 1.4e-14 53.4 2.2 1.4e-14 53.4 2.2 2.4 2 0 0 2 2 1 1 Putative Fe-S cluster Fer4 PF00037.27 AFI85446.1 - 2e-14 52.7 26.2 3.4e-09 36.1 4.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AFI85446.1 - 1.8e-09 38.0 16.8 0.00015 22.3 8.0 2.6 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI85446.1 - 2.2e-08 34.1 12.7 2.2e-08 34.1 12.7 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFI85446.1 - 2.2e-06 27.4 25.3 1.3e-05 24.9 2.5 3.7 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AFI85446.1 - 2.4e-06 27.3 4.5 2.4e-06 27.3 4.5 3.9 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_16 PF13484.6 AFI85446.1 - 3.8e-06 27.7 16.9 0.00061 20.7 1.7 3.1 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AFI85446.1 - 1e-05 25.6 15.1 1e-05 25.6 15.1 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AFI85446.1 - 0.0024 18.7 4.3 0.0024 18.7 4.3 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 AFI85446.1 - 0.018 15.5 20.7 0.92 10.0 14.9 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AFI85446.1 - 0.02 15.5 4.4 0.02 15.5 4.4 3.2 3 1 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AFI85446.1 - 0.025 15.3 5.8 0.025 15.3 5.8 3.7 1 1 2 3 3 3 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 AFI85446.1 - 0.049 14.2 21.0 0.35 11.5 4.0 3.2 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFI85446.1 - 0.053 14.1 3.0 0.053 14.1 3.0 3.7 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 AFI85446.1 - 0.29 11.4 16.1 1.9 8.7 5.0 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain EpuA PF11772.8 AFI85446.1 - 2.7 7.8 4.4 4.8 7.0 4.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF678 PF05077.12 AFI85446.1 - 7.2 6.8 7.8 2.1 8.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Fer4_22 PF17179.4 AFI85446.1 - 8.7 7.3 18.6 0.49 11.3 1.9 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Complex1_51K PF01512.17 AFI85447.1 - 2.1e-49 167.3 0.0 3.5e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit RnfC_N PF13375.6 AFI85447.1 - 3.4e-34 116.8 0.7 7.7e-34 115.7 0.7 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Fer4_10 PF13237.6 AFI85447.1 - 1.3e-08 34.8 6.2 3.5e-08 33.4 6.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain SLBB PF10531.9 AFI85447.1 - 4.1e-08 33.0 0.0 8.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Fer4_8 PF13183.6 AFI85447.1 - 3.3e-07 30.6 9.1 3.3e-07 30.6 9.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI85447.1 - 8.3e-07 29.5 9.4 2.3e-06 28.1 9.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI85447.1 - 6.5e-06 26.2 9.8 1.9e-05 24.7 9.8 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain NQRA PF05896.11 AFI85447.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Fer4_17 PF13534.6 AFI85447.1 - 5.8e-05 23.6 13.6 9.6e-05 22.9 11.2 2.6 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AFI85447.1 - 0.00067 19.4 18.6 0.0057 16.4 4.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AFI85447.1 - 0.0013 19.6 15.3 0.035 15.0 11.6 3.1 2 1 1 3 3 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AFI85447.1 - 0.0029 18.0 10.8 0.34 11.5 1.0 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AFI85447.1 - 0.0034 17.5 10.2 0.038 14.1 9.4 2.7 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI85447.1 - 0.0053 16.8 3.1 0.0053 16.8 3.1 2.6 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_22 PF17179.4 AFI85447.1 - 0.007 17.2 9.8 0.14 13.0 3.2 2.7 3 0 0 3 3 2 2 4Fe-4S dicluster domain FmiP_Thoc5 PF09766.9 AFI85447.1 - 0.012 15.0 2.5 0.017 14.4 2.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Fer4_2 PF12797.7 AFI85447.1 - 0.019 15.0 19.4 0.26 11.5 5.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Biotin_lipoyl PF00364.22 AFI85447.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme Fer4_3 PF12798.7 AFI85447.1 - 0.28 12.2 19.1 1 10.4 4.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AFI85447.1 - 4.5 7.5 17.3 0.16 12.2 1.2 3.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain NQR2_RnfD_RnfE PF03116.15 AFI85448.1 - 3.6e-103 345.0 18.7 4.4e-103 344.7 18.7 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family FMN_bind PF04205.14 AFI85449.1 - 1.5e-19 70.3 0.1 2.8e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 FMN-binding domain Rnf-Nqr PF02508.14 AFI85450.1 - 3.6e-62 209.4 10.5 4.2e-62 209.2 10.5 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF2070 PF09843.9 AFI85450.1 - 1.2 7.3 6.9 1.5 7.0 6.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HhH-GPD PF00730.25 AFI85451.1 - 1.1e-18 67.6 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AFI85451.1 - 4.9e-09 35.6 0.1 1e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AFI85451.1 - 7.9e-07 29.2 4.7 1.2e-06 28.6 4.7 1.3 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_8 PF14716.6 AFI85451.1 - 0.029 14.7 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_5 PF14520.6 AFI85451.1 - 0.092 13.4 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1841 PF08897.11 AFI85452.1 - 2.1e-52 176.7 4.9 2.4e-52 176.6 4.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1841) Raf1_N PF18578.1 AFI85452.1 - 0.042 14.3 0.3 0.069 13.6 0.1 1.4 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain TPR_14 PF13428.6 AFI85452.1 - 0.057 14.3 2.4 0.66 10.9 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1561 PF07598.11 AFI85452.1 - 0.11 10.7 0.1 0.11 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) ADH_zinc_N_2 PF13602.6 AFI85453.1 - 4.5e-12 47.2 0.0 9.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 AFI85453.1 - 4.2e-11 42.9 0.0 2.4e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AFI85453.1 - 5.5e-08 32.7 0.2 1.1e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 AFI85453.1 - 0.0018 18.5 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.24 AFI85453.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Cytochrome_CBB3 PF13442.6 AFI85454.1 - 1.1e-15 57.7 0.1 1.9e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AFI85454.1 - 0.0016 19.5 1.9 0.019 16.1 0.4 2.6 2 1 0 2 2 2 1 Cytochrome c Cytochrom_C550 PF14495.6 AFI85454.1 - 0.013 15.2 0.3 0.05 13.3 0.2 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain HD PF01966.22 AFI85454.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 HD domain Proton_antipo_M PF00361.20 AFI85455.1 - 7.5e-66 222.3 22.3 7.5e-66 222.3 22.3 4.0 4 2 1 5 5 5 1 Proton-conducting membrane transporter MnhB PF04039.13 AFI85455.1 - 4.7e-37 127.1 11.5 4.7e-37 127.1 11.5 7.9 4 3 5 9 9 9 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 AFI85455.1 - 4e-19 68.5 11.3 4e-19 68.5 11.3 6.0 8 0 0 8 8 8 1 Domain of unknown function (DUF4040) Proton_antipo_N PF00662.20 AFI85455.1 - 1.7e-12 47.2 2.0 1.7e-12 47.2 2.0 4.7 5 0 0 5 5 5 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 AFI85455.1 - 0.047 13.3 2.9 5.6 6.5 0.3 2.7 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Oxidored_q2 PF00420.24 AFI85456.1 - 2.2e-22 78.7 2.5 2.7e-22 78.4 2.5 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF981 PF06168.11 AFI85456.1 - 0.016 15.1 3.3 0.024 14.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Phage_holin_3_6 PF07332.11 AFI85456.1 - 0.14 12.2 4.7 0.2 11.7 4.6 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Proton_antipo_M PF00361.20 AFI85457.1 - 1.7e-38 132.5 28.1 1.7e-38 132.5 28.1 2.1 1 1 1 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AFI85457.1 - 0.043 13.9 1.4 0.31 11.2 0.0 3.1 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADHdeh_related PF10125.9 AFI85457.1 - 0.56 9.5 31.0 0.012 15.0 9.1 3.0 2 1 1 3 3 3 0 NADH dehydrogenase I, subunit N related protein CBP_BcsF PF11120.8 AFI85457.1 - 1.9 8.6 5.2 2.2 8.4 2.0 2.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF MNHE PF01899.16 AFI85458.1 - 2.6e-44 150.5 2.1 3e-44 150.3 2.1 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit MrpF_PhaF PF04066.13 AFI85459.1 - 9e-20 70.8 4.6 9e-20 70.8 4.6 2.1 2 0 0 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) PhaG_MnhG_YufB PF03334.14 AFI85460.1 - 4.5e-28 97.3 9.2 5.3e-28 97.1 9.2 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter subunit DUF188 PF02639.14 AFI85461.1 - 1.6e-48 163.6 0.0 1.9e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 DUF5004 PF16395.5 AFI85462.1 - 0.0051 16.8 0.4 0.01 15.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5004) Lipocalin_4 PF13648.6 AFI85462.1 - 0.0052 17.7 0.5 0.012 16.6 0.5 1.6 1 1 0 1 1 1 1 Lipocalin-like domain tRNA_int_endo_N PF02778.14 AFI85462.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain MFS_1 PF07690.16 AFI85465.1 - 1.6e-29 102.9 85.4 6e-22 78.1 47.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AFI85465.1 - 2.5e-06 26.6 37.7 0.00025 20.0 16.0 2.2 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 AFI85465.1 - 0.00067 18.6 34.9 0.012 14.5 9.6 3.6 1 1 2 3 3 3 3 Sugar (and other) transporter DUF998 PF06197.13 AFI85465.1 - 0.0038 16.8 15.3 0.0038 16.8 15.3 3.9 1 1 3 4 4 4 1 Protein of unknown function (DUF998) DUF4191 PF13829.6 AFI85465.1 - 0.057 12.7 0.0 0.057 12.7 0.0 4.7 2 1 3 5 5 5 0 Domain of unknown function (DUF4191) MFS_3 PF05977.13 AFI85465.1 - 0.1 11.0 24.0 0.056 11.8 10.5 2.3 1 1 0 2 2 2 0 Transmembrane secretion effector HTH_Tnp_1 PF01527.20 AFI85466.1 - 4.4e-21 75.0 0.1 5.2e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AFI85466.1 - 2.2e-06 27.7 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AFI85466.1 - 3.1e-06 26.8 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AFI85466.1 - 5e-06 26.5 0.2 1.7e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AFI85466.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 AFI85466.1 - 6.4e-05 23.1 0.4 0.00013 22.1 0.4 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_Tnp_IS630 PF01710.16 AFI85466.1 - 0.002 18.2 0.3 0.0022 18.0 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.6 AFI85466.1 - 0.0053 16.3 0.0 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 AFI85466.1 - 0.0095 16.4 0.0 0.053 14.0 0.0 2.1 1 1 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain Mga PF05043.13 AFI85466.1 - 0.043 14.4 0.1 0.2 12.3 0.0 1.9 2 0 0 2 2 2 0 Mga helix-turn-helix domain TetR_N PF00440.23 AFI85466.1 - 0.046 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DUF1492 PF07374.11 AFI85466.1 - 0.072 13.3 0.3 0.26 11.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) Phage_CI_repr PF07022.13 AFI85466.1 - 0.074 13.1 0.1 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain rve_3 PF13683.6 AFI85467.1 - 3.1e-30 103.7 0.1 5.6e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 AFI85467.1 - 2.1e-22 79.6 0.0 2.9e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AFI85467.1 - 2.8e-09 37.0 1.8 5e-09 36.2 1.8 1.4 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_IS240 PF13610.6 AFI85467.1 - 9.9e-07 29.1 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 AFI85467.1 - 1.5e-05 25.0 0.3 2.9e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 AFI85467.1 - 3.7e-05 23.5 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3883 PF13020.6 AFI85469.1 - 1.4e-19 69.9 0.0 2.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF3307 PF11750.8 AFI85470.1 - 2e-18 66.7 5.3 2e-18 66.7 5.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3307) SatD PF16264.5 AFI85471.1 - 1.8e-06 27.7 0.8 3.2e-06 26.9 0.8 1.6 1 1 0 1 1 1 1 SatD family (SatD) SHE3 PF17078.5 AFI85471.1 - 0.0029 17.4 0.7 0.56 9.9 0.1 2.1 2 0 0 2 2 2 2 SWI5-dependent HO expression protein 3 AAA_28 PF13521.6 AFI85472.1 - 1e-11 45.4 0.1 1.1e-11 45.3 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AFI85472.1 - 0.00087 19.8 0.1 0.00087 19.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AFI85472.1 - 0.0012 19.2 0.0 0.0012 19.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI85472.1 - 0.0028 18.0 0.0 0.0031 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AFI85472.1 - 0.0062 16.9 0.0 0.0062 16.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AFI85472.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AFI85472.1 - 0.012 15.2 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AFI85472.1 - 0.022 14.7 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase KTI12 PF08433.10 AFI85472.1 - 0.027 13.9 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Roc PF08477.13 AFI85472.1 - 0.031 14.5 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AFI85472.1 - 0.032 14.7 0.1 0.033 14.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AFI85472.1 - 0.034 13.5 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 AFI85472.1 - 0.037 14.4 0.1 0.037 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AFI85472.1 - 0.038 14.1 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase CoaE PF01121.20 AFI85472.1 - 0.043 13.5 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Dephospho-CoA kinase Viral_helicase1 PF01443.18 AFI85472.1 - 0.056 13.2 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 AFI85472.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_2 PF03668.15 AFI85472.1 - 0.066 12.5 0.0 0.077 12.3 0.0 1.0 1 0 0 1 1 1 0 P-loop ATPase protein family FeoB_N PF02421.18 AFI85472.1 - 0.067 12.7 0.1 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B Zeta_toxin PF06414.12 AFI85472.1 - 0.069 12.4 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 AFI85472.1 - 0.074 12.8 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AFI85472.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 AFI85472.1 - 0.11 12.6 0.1 0.14 12.3 0.1 1.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AFI85472.1 - 0.16 12.0 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 AFI85472.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2200 PF09966.9 AFI85473.1 - 1.7e-53 179.5 0.0 1.9e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) DUF2200 PF09966.9 AFI85475.1 - 4.3e-26 91.2 0.0 5.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) OB_NTP_bind PF07717.16 AFI85475.1 - 0.089 13.2 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Transposase_20 PF02371.16 AFI85476.1 - 1.3e-16 60.6 0.2 4.3e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 AFI85476.1 - 0.064 13.1 0.4 0.064 13.1 0.4 2.0 3 0 0 3 3 3 0 Transposase DUF4485 PF14846.6 AFI85476.1 - 0.09 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) Beta-Casp PF10996.8 AFI85477.1 - 4.3e-25 88.2 0.0 1.1e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 AFI85477.1 - 2.2e-15 57.2 1.6 6e-15 55.8 0.9 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 AFI85477.1 - 6.3e-15 54.9 0.0 2.1e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AFI85477.1 - 1.4e-13 50.7 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AFI85477.1 - 9.5e-13 48.1 0.1 2.9e-12 46.5 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF4437 PF14499.6 AFI85478.1 - 7.3e-05 22.0 0.0 9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_1 PF00190.22 AFI85478.1 - 0.00068 19.3 0.0 0.00097 18.8 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 AFI85478.1 - 0.0096 15.8 0.1 0.017 15.0 0.1 1.5 1 1 0 1 1 1 1 ChrR Cupin-like domain AraC_binding PF02311.19 AFI85478.1 - 0.11 12.4 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain LEA_3 PF03242.13 AFI85480.1 - 0.073 13.8 0.7 0.073 13.8 0.7 1.6 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF1775 PF07987.11 AFI85481.1 - 1.5e-41 142.1 0.8 4.5e-40 137.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unkown function (DUF1775) DUF913 PF06025.12 AFI85481.1 - 0.031 13.3 3.6 0.039 12.9 3.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) KfrA_N PF11740.8 AFI85481.1 - 0.22 12.2 5.5 0.49 11.1 5.5 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RP-C_C PF11800.8 AFI85481.1 - 0.4 10.7 6.7 0.55 10.3 6.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF5427 PF10310.9 AFI85481.1 - 1 8.3 15.7 1.3 7.9 15.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ASD2 PF08687.11 AFI85481.1 - 2.3 7.7 8.9 3.1 7.3 8.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 UvrD-helicase PF00580.21 AFI85482.1 - 2.8e-76 257.0 0.3 2.2e-75 254.1 0.3 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AFI85482.1 - 4.8e-72 243.2 0.6 2.9e-71 240.7 0.6 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AFI85482.1 - 3.4e-34 118.3 0.0 7.1e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AFI85482.1 - 6.6e-11 41.9 0.0 1.8e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 AFI85482.1 - 1.3e-08 34.9 0.2 0.0046 16.7 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AFI85482.1 - 2.3e-07 30.7 1.6 4.7e-05 23.2 0.1 2.6 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 AFI85482.1 - 0.0031 17.2 1.9 0.12 12.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain DUF445 PF04286.12 AFI85482.1 - 0.054 13.3 0.4 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Mg_chelatase PF01078.21 AFI85483.1 - 2.8e-96 320.8 0.0 4.3e-96 320.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 AFI85483.1 - 3.4e-48 162.5 0.0 5.9e-48 161.7 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 AFI85483.1 - 2.4e-32 111.4 0.9 6.4e-32 110.1 0.9 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_5 PF07728.14 AFI85483.1 - 4.5e-09 36.4 0.0 2.3e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AFI85483.1 - 5.4e-09 35.5 0.0 1e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 AFI85483.1 - 3.4e-07 30.1 0.0 3.2e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Lon_C PF05362.13 AFI85483.1 - 7.9e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain RuvB_N PF05496.12 AFI85483.1 - 0.00046 20.0 0.0 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AFI85483.1 - 0.00071 20.0 0.1 0.0029 18.0 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI85483.1 - 0.0025 18.2 0.1 0.012 16.0 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_11 PF13086.6 AFI85483.1 - 0.0059 16.4 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 AFI85483.1 - 0.013 15.6 0.0 0.14 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 AFI85483.1 - 0.039 13.5 0.0 0.097 12.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 AFI85483.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 AFI85483.1 - 0.053 13.7 0.2 0.16 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 AFI85483.1 - 0.056 13.0 1.7 0.17 11.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AFI85483.1 - 0.064 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 AFI85483.1 - 0.065 13.3 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 AFI85483.1 - 0.071 13.4 0.1 0.78 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 AFI85483.1 - 0.092 11.9 0.0 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 AFI85483.1 - 0.1 12.3 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 AFI85483.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFI85483.1 - 0.12 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 AFI85483.1 - 0.13 12.2 0.0 14 5.5 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) YrhC PF14143.6 AFI85485.1 - 0.76 9.9 5.2 0.31 11.2 1.3 2.1 1 1 1 2 2 2 0 YrhC-like protein CCB1 PF12046.8 AFI85485.1 - 0.84 9.0 3.8 1 8.7 3.8 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF2207 PF09972.9 AFI85485.1 - 5.4 5.7 4.6 5.8 5.5 4.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 AFI85485.1 - 6.1 6.5 10.9 7.5 6.2 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HTH_1 PF00126.27 AFI85486.1 - 7.4e-19 67.5 0.2 7.4e-19 67.5 0.2 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AFI85486.1 - 3.2e-14 52.8 0.1 8.3e-14 51.4 0.1 1.6 1 1 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 AFI85486.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 AFI85486.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AFI85486.1 - 0.15 11.6 1.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 AFI85486.1 - 0.17 11.6 0.8 0.42 10.3 0.3 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 AFI85486.1 - 1 9.3 3.0 0.62 10.0 0.3 2.0 3 0 0 3 3 3 0 MarR family MCPsignal PF00015.21 AFI85487.1 - 5.6e-43 146.7 24.9 5.6e-43 146.7 24.9 4.9 2 1 4 6 6 6 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AFI85487.1 - 3.1e-11 43.5 3.6 1.2e-09 38.4 0.0 4.5 4 1 1 5 5 5 1 HAMP domain DUF3040 PF11239.8 AFI85487.1 - 0.004 17.4 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Vip3A_N PF12495.8 AFI85487.1 - 0.0065 16.4 1.4 0.0065 16.4 1.4 3.8 3 1 1 4 4 4 1 Vegetative insecticide protein 3A N terminal ATG16 PF08614.11 AFI85487.1 - 0.0097 16.2 8.8 0.0097 16.2 8.8 4.1 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) XPC-binding PF09280.11 AFI85487.1 - 0.16 11.8 2.4 1.7 8.5 0.4 2.8 2 0 0 2 2 2 0 XPC-binding domain ZapD PF07072.11 AFI85487.1 - 3.8 7.2 21.3 0.66 9.7 0.5 4.6 4 2 1 5 5 5 0 Cell division protein DUF481 PF04338.12 AFI85488.1 - 0.0025 17.9 0.0 0.0025 17.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF481 DUF481 PF04338.12 AFI85489.1 - 4.7e-17 62.7 0.8 5.1e-17 62.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF481 LysR_substrate PF03466.20 AFI85490.1 - 5.6e-35 120.6 0.0 8.2e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AFI85490.1 - 1.7e-15 56.7 0.1 3.2e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AFI85490.1 - 0.0045 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AFI85490.1 - 0.032 13.8 0.0 0.086 12.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PBP_like PF12727.7 AFI85490.1 - 0.047 12.8 0.0 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 PBP superfamily domain HTH_28 PF13518.6 AFI85490.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AFI85490.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family 2-Hacid_dh_C PF02826.19 AFI85491.1 - 7.5e-53 178.5 0.1 1.4e-52 177.6 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AFI85491.1 - 4.5e-28 97.6 0.0 5.3e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 AFI85491.1 - 9.2e-09 35.1 0.1 6.6e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 AFI85491.1 - 3e-08 34.0 0.0 6.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 AFI85491.1 - 2.3e-07 30.3 0.0 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 AFI85491.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 AFI85491.1 - 4.6e-06 26.8 0.0 8.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AFI85491.1 - 0.00025 20.7 0.0 0.00062 19.4 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA PDH PF02153.17 AFI85491.1 - 0.00086 18.4 0.0 0.0022 17.0 0.0 1.6 2 0 0 2 2 2 1 Prephenate dehydrogenase Shikimate_DH PF01488.20 AFI85491.1 - 0.0031 17.6 0.1 0.0073 16.4 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 AFI85491.1 - 0.0053 17.0 0.1 0.017 15.4 0.0 2.0 2 1 0 2 2 1 1 TrkA-N domain NAD_binding_7 PF13241.6 AFI85491.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 AFI85491.1 - 0.056 13.4 1.5 5.5 6.9 1.5 2.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 AFI85491.1 - 0.12 12.3 0.6 0.36 10.7 0.1 2.0 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AFI85491.1 - 0.14 12.0 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Rossmann-like domain ThiF PF00899.21 AFI85491.1 - 0.14 11.5 0.6 0.45 9.8 0.3 1.9 1 1 1 2 2 2 0 ThiF family Semialdhyde_dh PF01118.24 AFI85491.1 - 0.22 12.0 1.3 1.3 9.4 0.5 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AFI85491.1 - 0.93 9.8 3.4 8.8 6.6 0.4 3.1 2 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain BPD_transp_1 PF00528.22 AFI85492.1 - 3.5e-23 82.3 8.2 3.5e-23 82.3 8.2 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AFI85493.1 - 9.7e-29 100.6 0.0 1.4e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI85493.1 - 9.1e-08 32.3 0.9 0.0044 16.9 0.4 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI85493.1 - 2.3e-05 24.0 0.2 0.00032 20.2 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AFI85493.1 - 8.7e-05 23.0 1.8 0.0032 17.9 0.3 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 AFI85493.1 - 0.00025 19.9 0.0 0.19 10.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AFI85493.1 - 0.00054 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AFI85493.1 - 0.00082 19.3 0.3 0.0023 17.8 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 AFI85493.1 - 0.0038 17.8 0.0 0.0069 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AFI85493.1 - 0.0074 16.0 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 AFI85493.1 - 0.03 13.9 0.7 0.18 11.4 0.7 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AFI85493.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2813 PF11398.8 AFI85493.1 - 0.064 12.5 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_22 PF13401.6 AFI85493.1 - 0.07 13.4 0.1 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AFI85493.1 - 0.1 12.8 0.0 1.5 9.1 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ppnp PF06865.11 AFI85494.1 - 1e-38 131.6 0.0 1.2e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase Cupin_3 PF05899.12 AFI85494.1 - 0.016 14.8 0.0 0.068 12.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AFI85494.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain BMFP PF04380.13 AFI85495.1 - 1e-31 109.2 3.8 1.1e-31 109.1 3.8 1.0 1 0 0 1 1 1 1 Membrane fusogenic activity Kdo PF06293.14 AFI85496.1 - 1.6e-27 96.2 2.6 2e-27 95.9 2.6 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AFI85496.1 - 0.014 15.4 0.0 0.057 13.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2459 PF09601.10 AFI85496.1 - 0.02 14.7 0.0 0.049 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) DUF853 PF05872.12 AFI85497.1 - 1.8e-230 765.8 4.5 5.5e-230 764.2 4.5 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 AFI85497.1 - 4.8e-05 22.8 0.5 0.00081 18.8 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF87 PF01935.17 AFI85497.1 - 5.1e-05 23.5 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_10 PF12846.7 AFI85497.1 - 5.2e-05 22.3 0.0 0.0074 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain ResIII PF04851.15 AFI85497.1 - 0.00013 22.0 0.0 0.043 13.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zot PF05707.12 AFI85497.1 - 0.0004 20.1 0.0 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 AFI85497.1 - 0.00056 20.2 0.8 0.12 12.6 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 AFI85497.1 - 0.00068 20.1 0.1 2.2 8.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI85497.1 - 0.005 17.2 7.1 1.2 9.5 0.0 3.5 2 1 2 4 4 4 2 AAA ATPase domain AAA_30 PF13604.6 AFI85497.1 - 0.0051 16.6 0.1 0.028 14.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 AFI85497.1 - 0.0053 15.7 0.5 0.016 14.1 0.0 1.9 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 AFI85497.1 - 0.0093 15.2 0.7 2.7 7.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 AFI85497.1 - 0.0098 16.2 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 AFI85497.1 - 0.021 13.9 1.1 0.17 10.9 0.1 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein CbiA PF01656.23 AFI85497.1 - 0.028 14.5 0.0 0.093 12.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 AFI85497.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 AFI85497.1 - 0.18 10.8 0.1 0.33 9.9 0.1 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 AFI85497.1 - 0.24 11.6 0.9 0.58 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF1043 PF06295.12 AFI85498.1 - 5.2e-10 39.4 0.0 6.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Halo_GVPC PF05465.13 AFI85498.1 - 0.0047 17.1 1.2 0.008 16.4 1.2 1.3 1 0 0 1 1 1 1 Halobacterial gas vesicle protein C (GVPC) repeat SLATT_fungal PF18142.1 AFI85498.1 - 0.0067 16.4 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain TarH PF02203.15 AFI85498.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Arfaptin PF06456.13 AFI85498.1 - 0.065 12.8 0.1 0.084 12.4 0.1 1.1 1 0 0 1 1 1 0 Arfaptin-like domain ApoO PF09769.9 AFI85498.1 - 0.071 13.1 3.9 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 Apolipoprotein O Wx5_PLAF3D7 PF09688.10 AFI85498.1 - 0.082 12.9 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Lig_chan PF00060.26 AFI85498.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel Trep_dent_lipo PF09710.10 AFI85498.1 - 0.15 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) DUF4229 PF14012.6 AFI85498.1 - 0.16 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) AAA_30 PF13604.6 AFI85499.1 - 1.9e-30 106.0 0.1 1.7e-29 102.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AFI85499.1 - 1e-26 94.0 0.2 2.6e-26 92.7 0.1 1.7 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 AFI85499.1 - 9.9e-16 58.2 2.0 1.3e-08 34.9 0.1 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 AFI85499.1 - 7.7e-15 54.5 0.0 1.5e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 AFI85499.1 - 5.6e-11 42.7 1.9 6.1e-07 29.5 0.1 2.3 1 1 1 2 2 2 2 AAA domain DUF2075 PF09848.9 AFI85499.1 - 1.9e-10 40.6 0.0 8.2e-10 38.4 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 AFI85499.1 - 1.1e-08 35.1 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Helicase SH3_13 PF18335.1 AFI85499.1 - 4e-08 33.0 0.0 1.9e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 AFI85499.1 - 1.6e-05 25.2 0.0 5.7e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 AFI85499.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 AFI85499.1 - 0.00015 21.6 0.1 0.0018 18.1 0.0 2.4 3 0 0 3 3 2 1 DEAD/DEAH box helicase PIF1 PF05970.14 AFI85499.1 - 0.00018 20.8 0.0 0.00035 19.9 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase UvrD-helicase PF00580.21 AFI85499.1 - 0.00026 20.6 0.1 0.00059 19.5 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 AFI85499.1 - 0.00045 20.7 0.8 0.002 18.5 0.3 2.3 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 AFI85499.1 - 0.0066 15.9 0.3 5.3 6.4 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein T2SSE PF00437.20 AFI85499.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 AFI85499.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AFI85499.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA PF00004.29 AFI85499.1 - 0.018 15.5 0.0 0.05 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AFI85499.1 - 0.025 14.3 0.0 1.2 8.9 0.1 2.7 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 AFI85499.1 - 0.031 14.5 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 AFI85499.1 - 0.031 12.2 0.1 0.23 9.3 0.0 2.0 2 0 0 2 2 2 0 Helicase CbiA PF01656.23 AFI85499.1 - 0.044 13.8 0.1 0.082 13.0 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 AFI85499.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AFI85499.1 - 0.085 12.8 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 AFI85499.1 - 0.086 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 AFI85499.1 - 0.093 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 AFI85499.1 - 0.094 12.0 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Rad17 PF03215.15 AFI85499.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 AFI85499.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.21 AFI85500.1 - 7.7e-63 212.9 4.5 7.7e-63 212.9 4.5 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AFI85500.1 - 1.4e-22 80.6 0.0 1.8e-21 77.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 AFI85500.1 - 3.8e-22 79.2 0.0 2.7e-18 66.5 0.0 4.3 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AFI85500.1 - 3.7e-12 45.9 0.0 3.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AFI85500.1 - 2.3e-08 34.0 0.1 0.00089 19.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain PDDEXK_1 PF12705.7 AFI85500.1 - 3.6e-07 30.3 0.5 4.8e-06 26.7 0.1 3.2 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF2075 PF09848.9 AFI85500.1 - 1.9e-05 24.1 0.3 0.049 12.9 0.2 2.6 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_12 PF13087.6 AFI85500.1 - 0.00011 21.9 0.5 0.06 13.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Rhamno_transf PF11316.8 AFI85500.1 - 0.00036 20.0 1.3 0.077 12.4 0.1 3.1 3 0 0 3 3 3 1 Putative rhamnosyl transferase Viral_helicase1 PF01443.18 AFI85500.1 - 0.0012 18.6 0.1 2.4 7.8 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 AFI85500.1 - 0.0016 18.4 0.0 0.0057 16.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 AFI85500.1 - 0.0035 17.6 0.3 7.3 6.9 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 AFI85500.1 - 0.0039 17.0 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 AFI85500.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Helicase DUF349 PF03993.12 AFI85500.1 - 1 9.7 5.1 0.93 9.8 0.4 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Exonuc_V_gamma PF04257.14 AFI85501.1 - 1e-254 847.4 10.9 1.2e-254 847.1 10.9 1.0 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 AFI85501.1 - 1.6e-55 188.0 7.0 1.6e-55 188.0 7.0 3.6 3 1 0 3 3 3 1 RecC C-terminal domain PqqD PF05402.12 AFI85503.1 - 7.5e-05 23.0 0.0 0.00013 22.2 0.0 1.4 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) Lant_dehydr_N PF04738.13 AFI85503.1 - 0.017 13.3 0.0 0.017 13.3 0.0 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Putative_PNPOx PF01243.20 AFI85504.1 - 2.9e-12 46.6 0.0 4.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SpoU_methylas_C PF12105.8 AFI85504.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Radical_SAM PF04055.21 AFI85505.1 - 1.8e-12 48.0 0.0 5.1e-12 46.5 0.0 1.7 1 1 1 2 2 2 1 Radical SAM superfamily HATPase_c PF02518.26 AFI85507.1 - 1.4e-20 73.9 1.1 2.9e-20 72.8 0.5 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI85507.1 - 9.1e-12 44.8 0.8 2.2e-11 43.6 0.5 1.9 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AFI85507.1 - 9.8e-08 32.3 0.0 2.4e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AFI85507.1 - 0.00047 20.1 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AFI85507.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AFI85507.1 - 0.018 14.9 0.1 0.084 12.8 0.0 2.1 2 1 0 2 2 2 0 GHKL domain Response_reg PF00072.24 AFI85508.1 - 3.5e-27 94.8 0.0 7.5e-27 93.7 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI85508.1 - 1e-19 70.4 0.4 2.1e-19 69.4 0.2 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal OEP PF02321.18 AFI85509.1 - 3.5e-22 79.1 27.0 1.8e-12 47.5 3.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein MRP-S26 PF14943.6 AFI85509.1 - 0.0098 15.8 0.5 0.031 14.2 0.5 1.8 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 CsiV PF10972.8 AFI85509.1 - 0.17 11.6 3.7 0.46 10.2 0.3 2.2 2 0 0 2 2 2 0 Peptidoglycan-binding protein, CsiV HlyD_D23 PF16576.5 AFI85510.1 - 1.3e-12 47.4 0.1 2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AFI85510.1 - 1.3e-08 35.5 0.2 1.2e-05 26.0 0.1 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AFI85510.1 - 3.9e-05 23.4 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like Metal_resist PF13801.6 AFI85510.1 - 0.029 14.5 0.3 0.052 13.7 0.3 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Biotin_lipoyl PF00364.22 AFI85510.1 - 0.05 13.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme ACR_tran PF00873.19 AFI85511.1 - 8e-286 950.8 15.9 9.1e-286 950.6 15.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF3240 PF11582.8 AFI85512.1 - 1.6e-15 57.1 0.0 1.7e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) Cytochrom_D1 PF02239.16 AFI85513.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain Metallophos PF00149.28 AFI85515.1 - 1.7e-15 58.0 0.1 3.2e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AFI85515.1 - 1.7e-10 41.4 0.0 3.5e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AFI85515.1 - 0.034 13.5 0.0 0.53 9.6 0.0 2.0 1 1 1 2 2 2 0 Metallophosphoesterase, calcineurin superfamily AAA_lid_4 PF17864.1 AFI85515.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain DAGK_cat PF00781.24 AFI85516.1 - 5.9e-19 67.9 0.7 1.1e-18 67.1 0.7 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 AFI85516.1 - 3.6e-05 23.1 0.1 5.2e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF4112 PF13430.6 AFI85517.1 - 3.3e-31 107.6 0.3 3.3e-31 107.6 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4112) Synaptobrevin PF00957.21 AFI85517.1 - 0.046 13.5 0.5 0.078 12.8 0.5 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF2207 PF09972.9 AFI85517.1 - 0.13 10.9 0.5 0.16 10.7 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 AFI85518.1 - 8.4e-21 74.8 0.1 4.2e-19 69.2 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AFI85518.1 - 1.3e-18 67.1 0.0 4.3e-18 65.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AFI85518.1 - 6e-16 59.7 0.0 7.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 AFI85518.1 - 9.3e-06 24.5 0.0 1.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.12 AFI85518.1 - 0.00031 19.9 0.0 0.00042 19.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 AFI85518.1 - 0.00074 19.3 0.0 0.0067 16.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 AFI85518.1 - 0.0018 17.3 0.0 0.0035 16.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 AFI85518.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 AFI85518.1 - 0.038 13.9 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 AFI85518.1 - 0.041 13.6 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 AFI85518.1 - 0.06 12.9 0.0 4.1 6.9 0.0 2.9 2 2 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 AFI85518.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Choline_transpo PF04515.12 AFI85518.1 - 0.087 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF915 PF06028.11 AFI85518.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 AFI85518.1 - 0.12 11.3 0.0 0.28 10.1 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.8 AFI85518.1 - 0.16 11.5 0.2 6.3 6.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) Ni_hydr_CYTB PF01292.20 AFI85519.1 - 1e-14 54.5 3.4 1.1e-14 54.5 3.4 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AFI85519.1 - 3.4e-07 30.7 3.9 5.3e-07 30.1 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) DUF2427 PF10348.9 AFI85519.1 - 0.42 10.4 6.4 18 5.2 6.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Cellulose_synt PF03552.14 AFI85521.1 - 0.36 9.3 3.1 0.5 8.8 3.1 1.1 1 0 0 1 1 1 0 Cellulose synthase CDP-OH_P_transf PF01066.21 AFI85521.1 - 2.2 9.1 7.8 66 4.4 7.8 2.6 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase LamB_YcsF PF03746.16 AFI85523.1 - 1.5e-96 322.7 0.1 1.7e-96 322.5 0.1 1.0 1 0 0 1 1 1 1 LamB/YcsF family CT_C_D PF02682.16 AFI85524.1 - 3e-65 219.8 0.0 3.4e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_A_B PF02626.15 AFI85525.1 - 6.9e-81 271.8 0.0 7.9e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B PRK PF00485.18 AFI85526.1 - 3.6e-69 232.5 0.0 4.5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 AFI85526.1 - 0.00093 18.5 0.0 0.009 15.3 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 AFI85526.1 - 0.053 13.4 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF4148 PF13663.6 AFI85526.1 - 0.087 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) FBPase PF00316.20 AFI85527.1 - 3.4e-11 43.0 0.0 3.5e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain F_bP_aldolase PF01116.20 AFI85528.1 - 1.1e-19 71.0 0.0 1.3e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II VapB_antitoxin PF09957.9 AFI85530.1 - 5.4e-18 64.6 0.8 6.6e-18 64.4 0.8 1.1 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB PIN PF01850.21 AFI85531.1 - 4.7e-10 40.0 0.0 5.9e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 PIN domain ABM PF03992.16 AFI85533.1 - 4.7e-07 29.8 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4286 PF14114.6 AFI85533.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) NYN PF01936.18 AFI85534.1 - 0.06 13.8 0.1 0.06 13.8 0.1 1.1 1 0 0 1 1 1 0 NYN domain PEP-CTERM PF07589.11 AFI85535.1 - 0.065 13.3 2.9 0.15 12.2 2.9 1.6 1 0 0 1 1 1 0 PEP-CTERM motif NYN PF01936.18 AFI85536.1 - 1.6e-32 113.0 0.1 2.2e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 AFI85536.1 - 2.4e-14 52.9 0.0 6.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PIN7 PF18475.1 AFI85536.1 - 0.057 14.1 0.1 0.13 12.9 0.0 1.7 2 0 0 2 2 2 0 PIN domain ParD_antitoxin PF03693.14 AFI85537.1 - 1.1e-08 35.4 0.3 1.1e-08 35.4 0.3 1.0 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH PLU-1 PF08429.11 AFI85537.1 - 0.15 11.2 0.2 0.15 11.2 0.2 1.0 1 0 0 1 1 1 0 PLU-1-like protein ParE_toxin PF05016.15 AFI85538.1 - 2e-05 25.1 0.0 2.1e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HicA_toxin PF07927.12 AFI85538.1 - 0.041 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, HigB-like_toxin PF05015.13 AFI85540.1 - 3.9e-15 56.0 0.0 4.2e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB BrnA_antitoxin PF14384.6 AFI85541.1 - 4.7e-09 36.6 0.0 5e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 BrnA antitoxin of type II toxin-antitoxin system CopG_antitoxin PF12441.8 AFI85541.1 - 3e-07 30.9 0.0 3.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system RHH_1 PF01402.21 AFI85541.1 - 0.024 14.5 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family HTH_3 PF01381.22 AFI85542.1 - 2.2e-08 34.0 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AFI85542.1 - 0.00047 20.1 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AFI85542.1 - 0.006 17.0 0.0 0.017 15.6 0.0 1.7 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 AFI85542.1 - 0.0071 16.2 0.1 0.042 13.7 0.0 2.1 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_31 PF13560.6 AFI85542.1 - 0.04 14.3 0.0 0.058 13.7 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 AFI85542.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HigB-like_toxin PF05015.13 AFI85543.1 - 3.7e-16 59.3 0.0 4e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB YoeB_toxin PF06769.14 AFI85543.1 - 0.093 12.8 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system MKT1_N PF12247.8 AFI85544.1 - 0.029 14.7 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Cu-oxidase_3 PF07732.15 AFI85545.1 - 1e-36 125.5 1.5 4.7e-31 107.3 0.2 2.1 1 1 1 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AFI85545.1 - 6.8e-23 80.9 8.5 1.1e-21 77.0 1.5 2.9 2 1 1 3 3 3 2 Multicopper oxidase Copper-bind PF00127.20 AFI85545.1 - 2.7e-05 24.5 0.3 5.7e-05 23.5 0.2 1.6 2 0 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cu-oxidase PF00394.22 AFI85545.1 - 0.00012 22.2 0.2 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.6 AFI85545.1 - 0.0055 16.8 0.0 0.031 14.4 0.0 2.0 2 1 0 2 2 2 1 Cupredoxin-like domain CopB PF05275.11 AFI85546.1 - 2.5e-57 193.8 0.8 3e-57 193.5 0.8 1.1 1 0 0 1 1 1 1 Copper resistance protein B precursor (CopB) Plug PF07715.15 AFI85547.1 - 9.1e-11 42.3 0.6 2.5e-10 40.9 0.3 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain DUF5640 PF18692.1 AFI85547.1 - 0.024 14.7 0.0 0.074 13.1 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5640) HlyIII PF03006.20 AFI85548.1 - 4.9e-29 101.6 10.7 5.6e-29 101.4 10.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related PRC PF05239.16 AFI85549.1 - 6e-14 51.9 0.2 1.2e-13 50.9 0.2 1.5 1 0 0 1 1 1 1 PRC-barrel domain LexA_DNA_bind PF01726.16 AFI85549.1 - 0.003 17.3 0.0 18 5.2 0.0 4.5 5 0 0 5 5 5 1 LexA DNA binding domain DUF2171 PF09939.9 AFI85549.1 - 0.0071 16.6 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2171) DUF3040 PF11239.8 AFI85549.1 - 0.96 9.8 4.0 68 3.8 0.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) SspO PF08175.12 AFI85549.1 - 4.3 7.9 11.2 55 4.3 0.1 5.3 1 1 4 5 5 5 0 Small acid-soluble spore protein O family TPM_phosphatase PF04536.14 AFI85551.1 - 3e-20 72.7 0.1 5.6e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 TPM domain PDZ_6 PF17820.1 AFI85551.1 - 5.8e-13 48.5 0.0 1.7e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 AFI85551.1 - 9.3e-12 45.1 0.0 1.5e-07 31.6 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AFI85551.1 - 3.7e-05 24.0 0.0 0.18 12.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain LemA PF04011.12 AFI85552.1 - 3e-49 166.7 5.2 1.6e-48 164.4 5.2 2.1 1 1 0 1 1 1 1 LemA family DUF2232 PF09991.9 AFI85552.1 - 0.0032 16.7 1.2 0.0054 16.0 1.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) DUF4064 PF13273.6 AFI85552.1 - 0.079 13.2 2.6 0.2 11.9 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4947 PF16305.5 AFI85552.1 - 0.11 12.5 0.6 4.2 7.3 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4947) DUF5531 PF17671.1 AFI85552.1 - 0.14 12.0 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Colicin_V PF02674.16 AFI85552.1 - 0.19 11.7 1.8 0.66 9.9 0.1 2.0 1 1 1 2 2 2 0 Colicin V production protein DUF2089 PF09862.9 AFI85553.1 - 2.8e-25 88.6 0.1 3.1e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_30 PF13556.6 AFI85553.1 - 0.00025 20.8 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_10 PF04967.12 AFI85553.1 - 0.0026 17.5 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HTH_24 PF13412.6 AFI85553.1 - 0.0049 16.4 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 AFI85553.1 - 0.016 14.9 0.2 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_Tnp_ISL3 PF13542.6 AFI85553.1 - 0.02 14.3 0.0 0.079 12.4 0.0 1.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 AFI85553.1 - 0.046 13.7 0.0 0.085 12.8 0.0 1.6 1 1 0 1 1 1 0 HTH domain Enolase_N PF03952.16 AFI85553.1 - 0.055 13.7 0.0 0.055 13.7 0.0 1.1 1 0 0 1 1 1 0 Enolase, N-terminal domain HTH_8 PF02954.19 AFI85553.1 - 0.064 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DUF596 PF04591.12 AFI85553.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 EamA PF00892.20 AFI85555.1 - 2.3e-16 60.2 42.3 6e-11 42.7 16.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family GYF_2 PF14237.6 AFI85556.1 - 0.00017 21.3 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 GYF domain 2 Acetyltransf_1 PF00583.25 AFI85557.1 - 4.4e-16 59.2 0.0 6.8e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AFI85557.1 - 1e-09 38.4 0.0 4.9e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AFI85557.1 - 1.1e-08 35.4 0.1 2.9e-08 34.0 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AFI85557.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 AFI85557.1 - 0.00028 21.6 0.0 0.00066 20.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AFI85557.1 - 0.0004 20.3 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AFI85557.1 - 0.0089 15.7 0.0 0.072 12.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_114 PF03537.13 AFI85557.1 - 0.074 12.4 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Acetyltransf_10 PF13673.7 AFI85558.1 - 3.1e-19 69.2 0.0 3.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AFI85558.1 - 4e-09 36.8 0.0 5.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AFI85558.1 - 2.1e-06 28.0 0.0 2.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 AFI85558.1 - 0.01 16.5 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AFI85558.1 - 0.043 13.9 0.1 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AFI85558.1 - 0.14 12.3 0.1 0.29 11.2 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 AFI85560.1 - 4.5e-30 104.8 0.0 2.3e-29 102.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2721 PF11026.8 AFI85562.1 - 9.2 6.2 9.5 2 8.3 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF3325 PF11804.8 AFI85563.1 - 1.1e-17 64.1 8.6 1.3e-17 63.8 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) p53-inducible11 PF14936.6 AFI85563.1 - 0.24 11.4 4.9 0.29 11.2 4.9 1.0 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 N6_N4_Mtase PF01555.18 AFI85564.1 - 6.6e-47 160.2 0.2 2.3e-46 158.4 0.2 1.8 1 1 0 1 1 1 1 DNA methylase PrmA PF06325.13 AFI85564.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 AFI85564.1 - 0.0003 20.5 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 AFI85564.1 - 0.001 18.8 0.0 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 AFI85564.1 - 0.0035 18.0 0.0 0.0096 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF2478 PF10649.9 AFI85564.1 - 0.088 12.4 0.1 0.24 11.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) Glyco_hydro_65m PF03632.15 AFI85564.1 - 0.14 11.0 0.1 1.2 7.9 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 65 central catalytic domain Fic_N PF13784.6 AFI85565.1 - 2.1e-23 82.1 0.0 2.1e-23 82.1 0.0 2.0 3 0 0 3 3 3 1 Fic/DOC family N-terminal Fic PF02661.18 AFI85565.1 - 4.6e-23 81.9 0.0 1.1e-22 80.7 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family DUF1612 PF07756.12 AFI85565.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1612) FtsK_gamma PF09397.10 AFI85565.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Ftsk gamma domain TrmB PF01978.19 AFI85565.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 AFI85565.1 - 0.057 13.4 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_13 PF11972.8 AFI85565.1 - 0.063 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_IclR PF09339.10 AFI85565.1 - 0.075 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 AFI85565.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF2250 PF10007.9 AFI85565.1 - 0.12 12.5 0.0 0.44 10.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) ResIII PF04851.15 AFI85566.1 - 5.1e-09 36.3 0.5 1e-08 35.4 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Tn7_Tnp_TnsA_N PF08722.11 AFI85566.1 - 0.003 17.7 0.0 0.0087 16.2 0.0 1.8 1 0 0 1 1 1 1 TnsA endonuclease N terminal DUF1064 PF06356.11 AFI85566.1 - 0.013 15.8 0.1 0.1 13.0 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1064) Pyr_redox_2 PF07992.14 AFI85567.1 - 2.4e-19 69.7 0.0 7.6e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AFI85567.1 - 0.027 15.0 0.4 0.65 10.6 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AFI85567.1 - 0.1 11.8 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HSP33 PF01430.19 AFI85568.1 - 1.4e-86 290.2 0.7 1.6e-86 290.0 0.7 1.0 1 0 0 1 1 1 1 Hsp33 protein DDE_Tnp_1_3 PF13612.6 AFI85570.1 - 4.7e-77 257.3 0.0 6.8e-77 256.8 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85570.1 - 1.2e-22 80.6 0.1 1.7e-21 76.8 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain Fic PF02661.18 AFI85571.1 - 1.1e-18 67.9 0.0 3.3e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family HTH_24 PF13412.6 AFI85571.1 - 0.0068 15.9 0.1 1.8 8.2 0.4 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding TrmB PF01978.19 AFI85571.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3665 PF12427.8 AFI85571.1 - 0.76 9.5 4.1 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 Branched-chain amino acid aminotransferase HSP90 PF00183.18 AFI85572.1 - 3.9e-143 478.1 6.7 7.2e-140 467.3 6.8 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 AFI85572.1 - 7.3e-14 52.2 0.3 1.3e-13 51.4 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AFI85572.1 - 1.3e-13 51.0 0.2 2.9e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TyeA PF09059.10 AFI85572.1 - 0.012 15.7 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 0 TyeA HP0268 PF18618.1 AFI85572.1 - 0.029 14.8 0.1 0.11 12.9 0.1 2.1 1 0 0 1 1 1 0 HP0268 ZinT PF09223.11 AFI85572.1 - 0.045 13.6 0.4 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment HEPN_RES_NTD1 PF18870.1 AFI85572.1 - 0.072 13.3 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 PhoU PF01895.19 AFI85572.1 - 4.2 7.9 14.1 7.4 7.1 0.3 5.2 5 1 0 5 5 5 0 PhoU domain MCPsignal PF00015.21 AFI85573.1 - 2.2e-45 154.5 17.8 2.2e-45 154.5 17.8 3.4 3 1 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AFI85573.1 - 3.1e-05 24.3 0.0 3.1e-05 24.3 0.0 3.9 6 0 0 6 6 6 1 HAMP domain DUF768 PF05589.11 AFI85573.1 - 0.081 12.9 0.8 0.32 11.0 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF768) Cupin_4 PF08007.12 AFI85573.1 - 2.1 7.8 7.6 4.9 6.5 1.1 3.1 3 0 0 3 3 3 0 Cupin superfamily protein H-kinase_dim PF02895.14 AFI85573.1 - 3.6 8.1 16.2 0.12 12.7 2.7 4.5 4 2 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain Folliculin PF11704.8 AFI85573.1 - 5.2 6.9 13.5 5.4 6.9 4.5 2.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Mce4_CUP1 PF11887.8 AFI85573.1 - 6.6 6.1 15.5 17 4.8 2.7 3.4 1 1 2 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative CheZ PF04344.13 AFI85573.1 - 7.4 6.4 22.5 3.7 7.4 2.7 4.2 3 1 1 4 4 4 0 Chemotaxis phosphatase, CheZ DUF1664 PF07889.12 AFI85573.1 - 9.1 6.3 29.6 0.18 11.9 6.4 4.8 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) EAL PF00563.20 AFI85574.1 - 5.7e-69 232.3 0.0 1e-68 231.4 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI85574.1 - 3.5e-40 137.4 0.5 2e-39 134.9 0.1 2.4 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AFI85574.1 - 1.2e-16 60.7 0.0 1.7e-15 57.0 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 AFI85574.1 - 3.4e-14 52.9 0.9 7.4e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 AFI85574.1 - 2.4e-07 31.0 0.0 7e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AFI85574.1 - 0.00013 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AFI85574.1 - 0.00019 21.4 0.0 0.00056 19.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain 4HB_MCP_1 PF12729.7 AFI85574.1 - 0.0019 17.8 11.6 0.0019 17.8 11.6 3.1 4 0 0 4 4 4 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 AFI85574.1 - 0.007 16.7 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 HAMP domain Spore_YhaL PF14147.6 AFI85574.1 - 3.3 7.5 9.0 11 5.8 1.5 3.5 3 0 0 3 3 3 0 Sporulation protein YhaL Exo_endo_phos PF03372.23 AFI85575.1 - 1.9e-13 50.5 0.2 2.5e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DotU PF09850.9 AFI85575.1 - 0.13 12.0 0.3 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Type VI secretion system protein DotU Sbt_1 PF05982.12 AFI85576.1 - 1.6e-98 329.8 31.2 1.8e-98 329.6 31.2 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily RELT PF12606.8 AFI85576.1 - 3.3 6.8 5.4 18 4.4 5.4 2.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Cation_efflux PF01545.21 AFI85577.1 - 7e-40 136.9 18.6 9.5e-40 136.5 18.6 1.1 1 0 0 1 1 1 1 Cation efflux family S_2TMBeta PF18153.1 AFI85577.1 - 0.027 14.3 0.6 0.052 13.3 0.4 1.7 1 1 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Tcp11 PF05794.13 AFI85578.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 T-complex protein 11 DUF421 PF04239.12 AFI85579.1 - 2.5e-14 53.0 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF421) GSH-S_ATP PF02955.16 AFI85579.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Fer2_BFD PF04324.15 AFI85579.1 - 0.12 12.7 0.1 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain CSD PF00313.22 AFI85580.1 - 1.5e-10 40.8 0.0 2.7e-10 40.0 0.0 1.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain YiiD_C PF09500.10 AFI85581.1 - 5.3e-47 159.3 0.0 5.9e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) DUF4442 PF14539.6 AFI85581.1 - 5.1e-07 29.9 0.0 6.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) GATase PF00117.28 AFI85582.1 - 8.5e-21 74.6 0.0 2.1e-20 73.3 0.0 1.6 1 1 1 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AFI85582.1 - 9.5e-07 28.8 0.1 2.3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 AFI85582.1 - 5.3e-05 23.1 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 AFI85582.1 - 0.00029 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CaMKII_AD PF08332.10 AFI85583.1 - 3.7e-24 85.3 0.0 4.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain DUF4440 PF14534.6 AFI85583.1 - 1.9e-15 57.1 0.0 2.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AFI85583.1 - 2e-13 50.7 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AFI85583.1 - 2e-10 41.2 0.2 2.8e-10 40.7 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 AFI85583.1 - 0.00017 21.7 1.2 0.0013 18.9 1.2 1.9 1 1 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.8 AFI85583.1 - 0.0017 18.1 0.1 0.0021 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) DUF2436 PF10365.9 AFI85583.1 - 0.079 12.7 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) DUF3096 PF11295.8 AFI85584.1 - 3.9e-18 64.8 17.0 4.8e-18 64.5 17.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3096) SLATT_6 PF18169.1 AFI85584.1 - 0.0027 17.4 4.7 0.0028 17.3 4.7 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 6 YtpI PF14007.6 AFI85584.1 - 0.18 11.9 6.2 0.19 11.9 6.2 1.0 1 0 0 1 1 1 0 YtpI-like protein DUF4834 PF16118.5 AFI85585.1 - 0.00075 20.4 1.6 0.00075 20.4 1.6 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) DUF4199 PF13858.6 AFI85585.1 - 0.0048 17.3 1.5 0.033 14.6 0.6 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF4199) ALG3 PF05208.13 AFI85585.1 - 0.0072 15.8 1.2 0.008 15.6 1.2 1.0 1 0 0 1 1 1 1 ALG3 protein Pex24p PF06398.11 AFI85585.1 - 0.011 14.8 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3169 PF11368.8 AFI85585.1 - 0.015 14.8 0.1 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) RSN1_TM PF13967.6 AFI85585.1 - 0.017 14.9 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Synaptobrevin PF00957.21 AFI85585.1 - 0.025 14.3 2.5 0.025 14.3 2.5 2.2 2 0 0 2 2 2 0 Synaptobrevin OSTbeta PF15048.6 AFI85585.1 - 0.041 14.0 0.2 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein SdpI PF13630.6 AFI85585.1 - 0.1 12.7 3.0 0.14 12.4 3.0 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2615 PF11027.8 AFI85585.1 - 0.14 12.3 1.9 0.5 10.5 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 AFI85585.1 - 0.18 12.7 3.0 0.57 11.1 3.0 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GGACT PF06094.12 AFI85586.1 - 2.4e-19 70.1 0.1 2.7e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like tRNA-synt_1c PF00749.21 AFI85587.1 - 8.6e-48 162.8 0.0 1.6e-47 161.9 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain LprI PF07007.12 AFI85589.1 - 3.1e-08 34.2 1.3 3.5e-08 34.0 1.3 1.1 1 0 0 1 1 1 1 Lysozyme inhibitor LprI DUF2508 PF10704.9 AFI85589.1 - 0.11 12.6 0.6 0.21 11.8 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) GGDEF PF00990.21 AFI85590.1 - 3.5e-42 143.9 0.5 5.2e-41 140.1 0.0 2.9 3 1 0 3 3 3 1 Diguanylate cyclase, GGDEF domain Mating_N PF12731.7 AFI85590.1 - 0.052 13.6 3.6 25 5.0 0.0 4.9 4 2 1 5 5 5 0 Mating-type protein beta 1 ArsR PF09824.9 AFI85590.1 - 0.064 12.9 0.4 0.24 11.0 0.1 2.2 2 0 0 2 2 2 0 ArsR transcriptional regulator Rx_N PF18052.1 AFI85590.1 - 0.11 12.8 4.3 1.2 9.4 0.6 3.3 2 1 0 2 2 2 0 Rx N-terminal domain DUF4407 PF14362.6 AFI85590.1 - 0.6 9.4 10.8 0.08 12.3 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 AFI85590.1 - 1.1 10.0 9.6 7.4 7.4 1.1 3.8 2 1 2 4 4 4 0 Occludin homology domain RPW8 PF05659.11 AFI85590.1 - 2 8.1 8.0 0.54 10.0 0.7 3.1 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Ku_C PF03730.14 AFI85590.1 - 3.9 8.2 8.4 8.3 7.2 1.1 3.7 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm E1-E2_ATPase PF00122.20 AFI85591.1 - 5e-57 192.3 1.1 1.2e-56 191.1 1.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 AFI85591.1 - 8.3e-45 153.7 5.4 1.6e-44 152.7 5.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AFI85591.1 - 4.8e-15 55.7 0.1 1e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AFI85591.1 - 7.5e-07 29.1 3.0 0.0003 20.6 1.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI85591.1 - 0.00031 21.2 0.5 0.0014 19.1 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 AFI85591.1 - 0.51 10.4 10.2 0.33 11.0 4.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) SKG6 PF08693.10 AFI85591.1 - 2 7.9 7.0 7.3 6.1 7.0 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CN_hydrolase PF00795.22 AFI85592.1 - 2.8e-29 102.2 0.0 3.7e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acetyltransf_1 PF00583.25 AFI85592.1 - 4.9e-06 26.8 0.0 1.7e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AFI85592.1 - 0.0041 17.5 0.0 0.01 16.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_18 PF13746.6 AFI85593.1 - 2.1e-39 134.2 7.5 6.6e-39 132.6 7.5 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 AFI85593.1 - 8.5e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_17 PF13534.6 AFI85593.1 - 3e-10 40.5 5.5 0.00016 22.2 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AFI85593.1 - 1.4e-08 35.2 5.1 4.7e-05 23.9 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_5 PF12801.7 AFI85593.1 - 5.9e-08 32.5 3.3 5.9e-08 32.5 3.3 4.2 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_8 PF13183.6 AFI85593.1 - 9.5e-07 29.2 5.1 0.0038 17.6 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AFI85593.1 - 2.1e-05 24.5 10.7 0.029 14.5 3.4 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI85593.1 - 0.0001 22.4 13.3 0.0044 17.1 2.2 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AFI85593.1 - 0.00019 21.1 21.7 0.00036 20.2 3.7 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AFI85593.1 - 0.00073 19.6 13.6 0.00073 19.6 13.6 1.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AFI85593.1 - 0.0011 18.9 2.9 0.0011 18.9 2.9 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_4 PF12800.7 AFI85593.1 - 0.0024 18.2 19.2 0.0049 17.3 3.2 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AFI85593.1 - 0.015 16.2 13.7 0.11 13.5 3.3 2.6 1 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AFI85593.1 - 0.021 14.9 3.3 0.021 14.9 3.3 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 AFI85593.1 - 0.029 14.9 12.4 0.11 13.1 0.9 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AFI85593.1 - 1.9 9.6 21.3 0.081 13.9 3.7 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Aminotran_1_2 PF00155.21 AFI85594.1 - 1.7e-15 57.1 0.0 2.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AFI85594.1 - 1.6e-13 50.1 0.1 4.8e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Cys_Met_Meta_PP PF01053.20 AFI85594.1 - 0.00027 19.6 0.0 0.00042 19.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_Crp_2 PF13545.6 AFI85594.1 - 0.0013 18.7 0.2 0.0053 16.7 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Aminotran_MocR PF12897.7 AFI85594.1 - 0.0053 15.6 0.0 0.0083 14.9 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase MarR_2 PF12802.7 AFI85594.1 - 0.046 13.6 0.4 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.6 AFI85594.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain EAL PF00563.20 AFI85595.1 - 8.6e-71 238.2 0.1 2.6e-70 236.6 0.1 1.9 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AFI85595.1 - 2.8e-44 150.7 0.2 7e-44 149.4 0.2 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain SBP_bac_3 PF00497.20 AFI85595.1 - 1.8e-25 89.7 0.0 6.9e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 PAS_4 PF08448.10 AFI85595.1 - 5.3e-15 55.6 0.0 2.5e-14 53.4 0.0 2.2 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AFI85595.1 - 1.1e-05 25.6 0.1 2.6e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 PAS domain NMT1 PF09084.11 AFI85595.1 - 7e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 NMT1/THI5 like PAS PF00989.25 AFI85595.1 - 0.0025 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold LapA_dom PF06305.11 AFI85595.1 - 0.005 16.6 1.7 0.013 15.3 1.7 1.7 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF948 PF06103.11 AFI85595.1 - 0.063 13.5 0.4 0.22 11.8 0.4 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Vps55 PF04133.14 AFI85595.1 - 0.093 12.7 0.0 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 55 DUF4083 PF13314.6 AFI85595.1 - 0.3 11.1 2.4 0.81 9.7 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) LigT_PEase PF02834.16 AFI85596.1 - 4.5e-16 58.8 0.0 7.6e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AFI85596.1 - 3.2e-06 27.1 0.1 4e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily GGDEF PF00990.21 AFI85597.1 - 4e-48 163.2 0.7 6.5e-48 162.5 0.7 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain SBP_bac_3 PF00497.20 AFI85597.1 - 2.6e-23 82.6 0.0 4.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 GGDEF_2 PF17853.1 AFI85597.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 GGDEF-like domain Ly49 PF08391.10 AFI85597.1 - 0.056 13.8 0.3 0.13 12.7 0.3 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Phage_FRD3 PF05798.11 AFI85597.1 - 0.059 13.6 0.0 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage FRD3 protein BatD PF13584.6 AFI85597.1 - 0.11 11.3 0.5 0.22 10.3 0.1 1.7 2 0 0 2 2 2 0 Oxygen tolerance DivIC PF04977.15 AFI85597.1 - 5.1 7.0 7.2 8.1 6.3 0.3 2.7 3 0 0 3 3 3 0 Septum formation initiator H2O2_YaaD PF03883.14 AFI85598.1 - 1.1e-96 322.9 0.4 1.2e-96 322.7 0.4 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA Rop PF01815.16 AFI85598.1 - 0.51 10.2 5.5 68 3.4 0.9 3.7 3 1 1 4 4 4 0 Rop protein DUF4389 PF14333.6 AFI85599.1 - 6.8e-27 93.2 2.3 8e-27 93.0 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4389) DctQ PF04290.12 AFI85600.1 - 8.9e-27 93.6 0.8 1.1e-26 93.3 0.8 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF5336 PF17270.2 AFI85600.1 - 0.06 13.0 0.1 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Sex_peptide PF08138.11 AFI85600.1 - 0.23 11.6 0.1 0.23 11.6 0.1 1.8 2 0 0 2 2 2 0 Sex peptide (SP) family DctM PF06808.12 AFI85601.1 - 2.3e-103 346.2 48.1 2.7e-103 346.0 48.1 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Na_H_antiporter PF03553.14 AFI85601.1 - 0.00089 18.6 10.4 0.00089 18.6 10.4 2.8 2 1 0 2 2 2 2 Na+/H+ antiporter family CitMHS PF03600.16 AFI85601.1 - 0.34 10.1 57.7 0.036 13.3 52.5 1.8 1 1 1 2 2 2 0 Citrate transporter tRNA-synt_2 PF00152.20 AFI85602.1 - 5.7e-40 137.3 0.0 5.3e-39 134.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 AFI85602.1 - 0.00083 18.9 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Elong-fact-P_C PF09285.11 AFI85603.1 - 1.6e-24 85.4 0.2 3.7e-24 84.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 AFI85603.1 - 6.2e-20 71.0 0.1 1.5e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AFI85603.1 - 7.6e-19 67.5 0.1 1.1e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain OB_aCoA_assoc PF01796.17 AFI85603.1 - 0.15 12.1 1.0 0.26 11.3 1.0 1.4 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated Radical_SAM PF04055.21 AFI85604.1 - 5.2e-08 33.4 0.0 6.4e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AFI85604.1 - 7.2e-07 29.6 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AFI85604.1 - 5.9e-06 26.4 0.0 9.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Citrate_synt PF00285.21 AFI85605.1 - 2.8e-129 431.3 0.0 3.2e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Nuc_recep-AF1 PF11825.8 AFI85605.1 - 0.044 13.8 0.1 0.083 12.9 0.1 1.5 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 FCSD-flav_bind PF09242.11 AFI85606.1 - 1.1e-22 80.1 0.9 3.3e-21 75.4 0.3 3.0 3 0 0 3 3 3 1 Flavocytochrome c sulphide dehydrogenase, flavin-binding Pyr_redox_2 PF07992.14 AFI85606.1 - 8.4e-14 51.5 0.0 6.3e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AFI85606.1 - 2.5e-07 30.6 0.0 1.1e-06 28.5 0.0 2.1 2 2 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AFI85606.1 - 2.9e-05 24.1 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AFI85606.1 - 6.7e-05 23.0 0.0 0.00037 20.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 AFI85606.1 - 0.00025 20.0 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 AFI85606.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 AFI85606.1 - 0.0016 17.7 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 AFI85606.1 - 0.017 14.4 0.1 0.093 12.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 AFI85606.1 - 0.024 15.2 0.0 0.068 13.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 AFI85606.1 - 0.087 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 AFI85606.1 - 0.089 11.8 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein Radical_SAM PF04055.21 AFI85607.1 - 3e-15 57.0 0.0 9.3e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 AFI85607.1 - 9.8e-07 29.2 0.1 2.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family BPL_LplA_LipB PF03099.19 AFI85608.1 - 6.3e-08 32.6 0.0 9.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF493 PF04359.14 AFI85609.1 - 1.1e-30 106.0 0.0 1.2e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) ACT_4 PF13291.6 AFI85609.1 - 0.065 13.8 0.0 0.074 13.6 0.0 1.1 1 0 0 1 1 1 0 ACT domain Aminotran_4 PF01063.19 AFI85610.1 - 3.1e-48 164.6 0.0 3.5e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_S11 PF00768.20 AFI85611.1 - 2.7e-83 279.1 0.1 3.7e-83 278.7 0.1 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AFI85611.1 - 1.2e-20 73.5 0.1 2.1e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AFI85611.1 - 5.1e-15 55.6 0.1 7.4e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 AFI85611.1 - 0.00056 19.2 0.0 0.0014 17.9 0.0 1.6 1 1 1 2 2 2 1 Beta-lactamase Peptidase_S13 PF02113.15 AFI85611.1 - 0.0033 16.2 0.1 0.03 13.1 0.0 2.0 1 1 1 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family T4SS_TraI PF16932.5 AFI85611.1 - 0.064 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer DPBB_1 PF03330.18 AFI85612.1 - 8.5e-26 90.1 0.0 1.9e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase SPOR PF05036.13 AFI85612.1 - 1e-09 38.6 0.1 2.5e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Sporulation related domain CAP160 PF07918.11 AFI85612.1 - 7.2 6.4 8.0 3.3 7.5 1.8 2.7 1 1 1 2 2 2 0 CAP160 repeat SLT_2 PF13406.6 AFI85613.1 - 3.1e-102 341.7 0.0 3.5e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT PF01464.20 AFI85613.1 - 0.00051 19.7 0.0 0.0031 17.1 0.0 2.2 1 1 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AFI85613.1 - 0.039 14.5 0.0 0.086 13.4 0.0 1.9 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase FTSW_RODA_SPOVE PF01098.19 AFI85614.1 - 2e-110 369.2 27.2 2.4e-110 369.0 27.2 1.0 1 0 0 1 1 1 1 Cell cycle protein Transpeptidase PF00905.22 AFI85615.1 - 6.3e-74 248.9 0.0 8.7e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AFI85615.1 - 1.2e-45 156.0 0.0 2e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MtrB PF05440.12 AFI85615.1 - 0.015 15.7 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B HrpF PF06266.12 AFI85615.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 HrpF protein ANAPC_CDC26 PF10471.9 AFI85615.1 - 0.087 13.7 0.1 0.21 12.5 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 MreD PF04093.12 AFI85616.1 - 1.5e-26 93.4 17.8 1.8e-26 93.1 17.8 1.0 1 0 0 1 1 1 1 rod shape-determining protein MreD MreC PF04085.14 AFI85617.1 - 2.8e-37 127.9 0.0 4.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 rod shape-determining protein MreC MreB_Mbl PF06723.13 AFI85618.1 - 4.5e-148 492.4 1.5 5.3e-148 492.2 1.5 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 AFI85618.1 - 1.6e-13 49.8 0.1 4.7e-13 48.2 0.1 1.8 1 1 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 AFI85618.1 - 1.4e-10 41.5 0.4 4e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Cell division protein FtsA Actin PF00022.19 AFI85618.1 - 3e-08 32.7 0.0 0.00011 20.9 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.8 AFI85618.1 - 1.4e-06 27.6 0.0 0.0029 16.7 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; EutA PF06277.11 AFI85618.1 - 0.00094 18.1 0.1 0.0017 17.3 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA DDR PF08841.10 AFI85618.1 - 0.0074 15.3 3.0 0.012 14.6 1.5 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Ppx-GppA PF02541.16 AFI85618.1 - 0.0082 15.6 0.1 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 Ppx/GppA phosphatase family StbA PF06406.11 AFI85618.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein Glu-tRNAGln PF02686.15 AFI85619.1 - 2.5e-17 62.9 0.1 4.6e-17 62.1 0.2 1.4 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Amidase PF01425.21 AFI85620.1 - 1.6e-162 541.6 0.1 1.8e-162 541.4 0.1 1.0 1 0 0 1 1 1 1 Amidase TPP_enzyme_N PF02776.18 AFI85621.1 - 1.7e-56 190.5 1.4 3.1e-55 186.4 0.2 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AFI85621.1 - 3.2e-44 150.4 0.2 7.6e-44 149.2 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AFI85621.1 - 7.3e-39 132.6 0.0 1.6e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Molybdopterin PF00384.22 AFI85621.1 - 0.0058 15.6 0.0 0.048 12.6 0.0 2.0 1 1 1 2 2 2 2 Molybdopterin oxidoreductase CO_dh PF02552.16 AFI85621.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AhpC-TSA PF00578.21 AFI85622.1 - 2.2e-23 82.5 0.0 3.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AFI85622.1 - 1.3e-19 70.4 0.0 1.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AFI85622.1 - 1.7e-08 34.6 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like GSHPx PF00255.19 AFI85622.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_2 PF13098.6 AFI85622.1 - 6.4e-05 23.4 0.0 0.00022 21.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 AFI85622.1 - 0.0015 18.4 0.0 0.0067 16.3 0.0 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein SCO1-SenC PF02630.14 AFI85622.1 - 0.0017 18.2 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin PF00085.20 AFI85622.1 - 0.0054 16.7 0.0 0.086 12.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Ribosomal_L28 PF00830.19 AFI85623.1 - 2.9e-28 97.8 2.5 3.4e-28 97.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L28 family BIV_Env PF05858.12 AFI85623.1 - 0.036 12.3 0.0 0.04 12.1 0.0 1.0 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Ribosomal_L33 PF00471.20 AFI85624.1 - 3.1e-17 62.8 0.2 3.4e-17 62.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 HDOD PF08668.12 AFI85625.1 - 1.7e-18 66.8 0.0 2.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 HDOD domain EAL PF00563.20 AFI85625.1 - 3.5e-12 46.3 0.1 9.7e-11 41.6 0.1 2.8 1 1 0 1 1 1 1 EAL domain ABC_tran PF00005.27 AFI85626.1 - 2.2e-31 109.2 0.0 3.8e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI85626.1 - 2.4e-11 44.0 2.1 1.1e-07 32.0 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AFI85626.1 - 0.00022 21.1 0.2 0.22 11.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 AFI85626.1 - 0.00034 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DUF4162 PF13732.6 AFI85626.1 - 0.0035 18.0 0.1 0.0074 17.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 AFI85626.1 - 0.012 15.1 0.2 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AFI85626.1 - 0.015 15.5 0.5 0.21 11.9 0.5 2.5 1 1 0 1 1 1 0 AAA domain NAD_binding_4 PF07993.12 AFI85626.1 - 0.021 14.0 0.1 1.7 7.8 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein MukB PF04310.12 AFI85626.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 MukB N-terminal AAA_10 PF12846.7 AFI85626.1 - 0.029 13.3 0.3 0.057 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.6 AFI85626.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AFI85626.1 - 0.051 13.7 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AFI85626.1 - 0.061 13.8 0.6 0.15 12.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AFI85626.1 - 0.065 12.9 0.2 0.36 10.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AFI85626.1 - 0.084 13.3 0.0 0.31 11.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AFI85626.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase PA28_beta PF02252.18 AFI85626.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit ABC2_membrane_3 PF12698.7 AFI85627.1 - 9.8e-11 41.3 31.6 9.8e-11 41.3 31.6 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AFI85627.1 - 7.8e-06 25.4 25.4 1.3e-05 24.7 25.4 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AFI85627.1 - 0.0026 17.3 21.3 0.0026 17.3 21.3 2.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AFI85627.1 - 0.0037 17.2 17.8 0.0037 17.2 17.8 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein Tweety PF04906.13 AFI85627.1 - 0.073 11.7 5.1 0.062 12.0 3.4 1.7 1 1 0 1 1 1 0 Tweety ABC2_membrane PF01061.24 AFI85627.1 - 0.86 9.0 38.4 0.22 10.9 31.8 2.5 1 1 1 2 2 2 0 ABC-2 type transporter ABC_transp_aux PF09822.9 AFI85628.1 - 9.6e-31 107.2 0.1 1.5e-29 103.3 0.1 2.1 1 1 0 1 1 1 1 ABC-type uncharacterized transport system DUF2194 PF09960.9 AFI85628.1 - 0.0023 16.3 0.0 0.0035 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) DUF4340 PF14238.6 AFI85629.1 - 1.3e-15 58.0 0.5 4.4e-14 52.9 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4340) FAD_binding_3 PF01494.19 AFI85629.1 - 0.053 12.7 0.1 0.077 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF2326 PF10088.9 AFI85629.1 - 0.09 12.5 0.9 0.28 10.9 0.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Fapy_DNA_glyco PF01149.24 AFI85630.1 - 3.9e-31 108.1 0.0 7.3e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AFI85630.1 - 3.5e-27 94.2 0.0 6.8e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AFI85630.1 - 4.9e-10 39.1 3.5 2e-09 37.1 2.7 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 AFI85630.1 - 0.00099 19.2 1.3 0.002 18.2 1.3 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zinc-ribbons_6 PF07191.12 AFI85630.1 - 0.0018 18.2 1.3 0.0031 17.5 1.3 1.3 1 0 0 1 1 1 1 zinc-ribbons A2L_zn_ribbon PF08792.10 AFI85630.1 - 0.0049 16.6 1.4 0.0086 15.8 1.4 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain HscB_4_cys PF18256.1 AFI85630.1 - 0.012 15.4 0.5 0.024 14.4 0.5 1.5 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DZR PF12773.7 AFI85630.1 - 0.02 14.9 2.2 0.038 14.0 2.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 AFI85630.1 - 0.1 12.5 2.1 0.73 9.8 2.3 2.2 2 1 0 2 2 2 0 Nudix N-terminal zf_UBZ PF18439.1 AFI85630.1 - 0.11 12.1 3.4 3.8 7.2 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 AFI85630.1 - 0.15 11.6 0.3 0.36 10.4 0.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding FbpA PF05833.11 AFI85630.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HypA PF01155.19 AFI85630.1 - 0.3 11.1 1.7 0.75 9.8 1.7 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 AFI85630.1 - 0.97 9.4 6.6 2 8.4 4.1 2.6 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 AFI85630.1 - 2.6 7.9 4.8 19 5.2 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AFI85630.1 - 4.7 7.2 6.2 0.73 9.8 2.1 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cytochrome_CBB3 PF13442.6 AFI85631.1 - 4.5e-05 23.7 0.1 5.3e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AFI85631.1 - 8.3e-05 23.7 0.5 0.00018 22.6 0.5 1.5 1 1 0 1 1 1 1 Cytochrome c PseudoU_synth_2 PF00849.22 AFI85632.1 - 2.8e-31 108.8 0.8 3.7e-31 108.4 0.8 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AFI85632.1 - 5.8e-10 38.7 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AFI85632.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 S4 domain Chromate_transp PF02417.15 AFI85633.1 - 9.2e-69 230.6 51.5 2.1e-36 125.4 19.3 2.3 3 0 0 3 3 3 2 Chromate transporter Sigma70_r4_2 PF08281.12 AFI85634.1 - 1.1e-16 60.2 0.3 5.2e-16 58.1 0.5 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AFI85634.1 - 6.9e-08 32.6 0.0 8.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r2 PF04542.14 AFI85634.1 - 8.6e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AFI85634.1 - 1.2e-07 31.1 0.1 2.4e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 PCI PF01399.27 AFI85634.1 - 0.00026 21.5 2.0 0.00054 20.4 1.7 1.8 1 1 0 1 1 1 1 PCI domain HTH_11 PF08279.12 AFI85634.1 - 0.00088 19.2 0.3 0.0022 17.9 0.1 1.8 2 0 0 2 2 2 1 HTH domain HTH_23 PF13384.6 AFI85634.1 - 0.00091 19.0 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_40 PF14493.6 AFI85634.1 - 0.0043 17.5 0.6 0.068 13.6 0.0 2.7 2 1 0 3 3 3 1 Helix-turn-helix domain GerE PF00196.19 AFI85634.1 - 0.0044 16.5 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TnsD PF15978.5 AFI85634.1 - 0.0067 15.5 0.7 0.084 11.9 0.1 2.2 1 1 0 2 2 2 1 Tn7-like transposition protein D DUF3885 PF13021.6 AFI85634.1 - 0.016 15.3 0.2 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) MarR PF01047.22 AFI85634.1 - 0.028 14.3 0.1 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 AFI85634.1 - 0.036 13.6 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Spo0A_C PF08769.11 AFI85634.1 - 0.038 14.1 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal HTH_3 PF01381.22 AFI85634.1 - 0.073 13.1 0.1 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 AFI85634.1 - 0.08 12.7 2.0 0.48 10.2 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_10 PF04967.12 AFI85634.1 - 0.091 12.6 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_31 PF13560.6 AFI85634.1 - 0.097 13.0 0.0 0.66 10.4 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain TonB_C PF03544.14 AFI85635.1 - 1.9e-18 66.7 0.0 5e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AFI85635.1 - 7.6e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 TonB C terminal Promethin PF16015.5 AFI85636.1 - 0.089 12.7 26.1 0.11 12.5 26.1 1.1 1 0 0 1 1 1 0 Promethin ExbD PF02472.16 AFI85637.1 - 1.6e-25 89.7 0.5 2.1e-25 89.4 0.5 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 AFI85638.1 - 3.8e-32 110.7 4.7 7.2e-32 109.8 4.7 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family POTRA_TamA_1 PF17243.2 AFI85638.1 - 0.031 14.4 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 POTRA domain TamA domain 1 Transket_pyr PF02779.24 AFI85638.1 - 0.21 11.2 1.4 0.34 10.6 0.8 1.7 1 1 0 1 1 1 0 Transketolase, pyrimidine binding domain DUF454 PF04304.13 AFI85639.1 - 4e-33 113.8 9.1 4.7e-33 113.6 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) Heme_oxygenase PF01126.20 AFI85640.1 - 9.1e-22 77.9 1.7 2.1e-21 76.7 1.7 1.5 1 1 0 1 1 1 1 Heme oxygenase TPR_12 PF13424.6 AFI85641.1 - 2.5e-34 117.4 43.3 8.8e-12 45.2 3.4 6.3 3 2 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 AFI85641.1 - 2.6e-16 58.3 34.3 0.0019 18.2 0.2 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 AFI85641.1 - 8.7e-15 53.6 25.5 0.13 12.4 0.7 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 AFI85641.1 - 1.7e-14 53.1 26.9 7.1e-07 28.9 0.2 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 AFI85641.1 - 2.4e-13 49.1 25.7 0.00023 21.1 0.3 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 AFI85641.1 - 5.4e-13 48.2 32.5 0.0017 18.1 0.1 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_MalT PF17874.1 AFI85641.1 - 6e-12 45.6 65.6 3.3e-07 30.0 14.7 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_16 PF13432.6 AFI85641.1 - 3e-07 31.0 32.2 0.37 11.5 0.1 7.3 7 3 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 AFI85641.1 - 1.2e-06 28.9 46.5 0.001 19.5 5.9 7.4 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 AFI85641.1 - 3.5e-06 27.4 25.0 0.29 12.1 0.2 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 AFI85641.1 - 6.7e-06 26.4 23.9 0.15 12.7 0.4 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 AFI85641.1 - 0.014 15.6 26.0 0.64 10.3 0.8 5.9 2 2 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 AFI85641.1 - 0.065 13.6 0.8 0.065 13.6 0.8 6.5 8 0 0 8 8 5 0 Tetratricopeptide repeat DUF4051 PF13260.6 AFI85641.1 - 0.068 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DUF2225 PF09986.9 AFI85641.1 - 0.13 12.0 19.6 0.16 11.7 0.6 3.8 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) HemY_N PF07219.13 AFI85641.1 - 0.25 11.5 15.1 0.78 10.0 0.1 4.2 3 3 1 4 4 4 0 HemY protein N-terminus DUF1415 PF07209.12 AFI85641.1 - 2 8.1 8.1 1.2 8.9 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1415) DUF2783 PF10932.8 AFI85641.1 - 7.6 6.3 7.5 13 5.5 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2783) DUF560 PF04575.13 AFI85642.1 - 3.6e-55 187.4 11.2 3.6e-55 187.4 11.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF560) TPR_19 PF14559.6 AFI85642.1 - 0.0096 16.4 1.0 0.023 15.2 1.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AFI85642.1 - 0.01 15.9 1.2 0.11 12.6 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AFI85642.1 - 0.019 15.8 2.2 0.7 10.9 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 AFI85642.1 - 0.029 15.0 1.5 0.082 13.6 1.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Gloverin PF10793.9 AFI85642.1 - 0.065 13.1 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Gloverin-like protein TbpB_B_D PF01298.18 AFI85643.1 - 1.8e-06 28.4 6.5 3.1e-06 27.6 6.5 1.4 1 0 0 1 1 1 1 C-lobe and N-lobe beta barrels of Tf-binding protein B TonB_dep_Rec PF00593.24 AFI85644.1 - 3e-34 119.7 17.1 3e-34 119.7 17.1 3.3 2 1 1 3 3 3 2 TonB dependent receptor Plug PF07715.15 AFI85644.1 - 3.1e-12 47.0 0.5 9.5e-12 45.4 0.5 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AFI85644.1 - 9.9e-08 31.7 0.1 3.4e-07 30.0 0.1 2.0 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AFI85645.1 - 4.5e-15 56.1 0.0 6.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AFI85645.1 - 1.9e-10 40.5 12.8 3.3e-10 39.7 12.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) DUF3876 PF12992.7 AFI85645.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) EFG_IV PF03764.18 AFI85646.1 - 2.4e-43 146.8 0.0 6.7e-43 145.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 AFI85646.1 - 7e-41 139.9 0.0 1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 AFI85646.1 - 1.5e-28 98.7 0.1 2.6e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AFI85646.1 - 3.3e-28 97.6 0.0 9.5e-28 96.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AFI85646.1 - 6.2e-18 65.0 0.2 1.4e-17 63.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AIG1 PF04548.16 AFI85646.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF2818 PF10993.8 AFI85648.1 - 2.3e-34 117.8 10.1 2.6e-34 117.6 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2818) DUF2070 PF09843.9 AFI85648.1 - 0.77 8.0 3.6 0.84 7.9 3.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Proton_antipo_M PF00361.20 AFI85649.1 - 2.2e-75 253.6 30.8 2.2e-75 253.6 30.8 2.5 2 0 0 2 2 2 2 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AFI85649.1 - 0.012 15.7 0.8 0.012 15.7 0.8 3.5 3 1 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus GET2 PF08690.10 AFI85649.1 - 1.6 8.3 5.1 0.22 11.1 0.4 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 Proton_antipo_M PF00361.20 AFI85650.1 - 1.7e-70 237.5 32.9 1.7e-70 237.5 32.9 3.3 2 2 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 AFI85650.1 - 3.9e-05 23.7 6.1 3.9e-05 23.7 6.1 4.7 4 2 0 4 4 4 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus Monellin PF09200.10 AFI85650.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Monellin DUF1240 PF06836.12 AFI85650.1 - 1.2 9.8 12.3 0.8 10.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) Proton_antipo_M PF00361.20 AFI85651.1 - 7.4e-88 294.5 27.6 7.4e-88 294.5 27.6 2.4 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AFI85651.1 - 6.6e-27 93.4 8.3 4.2e-26 90.8 8.3 2.6 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 AFI85651.1 - 0.068 12.8 0.0 0.068 12.8 0.0 2.8 3 0 0 3 3 3 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus GET2 PF08690.10 AFI85651.1 - 1.2 8.8 3.4 2 8.0 3.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Oxidored_q2 PF00420.24 AFI85652.1 - 1.4e-22 79.3 13.7 1.7e-22 79.1 13.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Gram_pos_anchor PF00746.21 AFI85652.1 - 3.6 7.6 4.8 8.8 6.4 0.1 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3488 PF11992.8 AFI85652.1 - 4.7 6.1 11.8 5.3 5.9 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Herpes_LMP1 PF05297.11 AFI85652.1 - 9.5 5.3 9.8 11 5.1 9.8 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Oxidored_q3 PF00499.20 AFI85653.1 - 6.9e-38 129.6 18.2 9.7e-38 129.1 18.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4083 PF13314.6 AFI85653.1 - 0.55 10.2 0.0 0.55 10.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) Fer4 PF00037.27 AFI85654.1 - 2.6e-13 49.2 14.9 1e-06 28.3 2.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AFI85654.1 - 1.2e-12 48.2 7.0 2e-12 47.5 7.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AFI85654.1 - 3.3e-10 40.3 2.3 0.00014 22.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AFI85654.1 - 1.6e-09 37.8 6.4 2.5e-09 37.1 6.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFI85654.1 - 1.9e-09 37.5 16.7 6.2e-07 29.4 10.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AFI85654.1 - 3.5e-09 36.7 4.5 4.1e-05 23.6 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AFI85654.1 - 3.7e-09 37.4 4.7 0.001 19.9 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 AFI85654.1 - 1.5e-07 31.3 9.5 6.2e-05 23.2 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AFI85654.1 - 4e-07 29.7 10.8 0.00043 20.2 3.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AFI85654.1 - 1.7e-06 27.9 13.4 0.00023 21.1 4.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AFI85654.1 - 7.4e-06 26.4 9.3 0.00091 19.7 10.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_22 PF17179.4 AFI85654.1 - 5.2e-05 24.0 1.4 0.11 13.4 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AFI85654.1 - 0.0017 19.1 14.7 0.17 12.9 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AFI85654.1 - 0.017 15.6 11.6 0.15 12.6 1.9 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 AFI85654.1 - 0.059 13.6 4.5 1.3 9.3 0.2 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 AFI85654.1 - 0.075 13.2 9.4 11 6.3 8.2 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 AFI85654.1 - 2.5 8.3 4.6 5.5 7.2 0.4 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NADHdh PF00146.21 AFI85655.1 - 4.6e-129 430.0 26.7 5.3e-129 429.8 26.7 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Molybdopterin PF00384.22 AFI85656.1 - 1.5e-40 139.5 0.0 5.8e-39 134.3 0.0 2.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 AFI85656.1 - 3.4e-18 65.5 0.1 7.5e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 AFI85656.1 - 5.9e-16 57.7 0.1 5.9e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 AFI85656.1 - 3.4e-08 33.3 1.8 4.5e-08 32.9 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molydop_binding PF01568.21 AFI85656.1 - 1.9e-07 31.1 0.0 4.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer4 PF00037.27 AFI85656.1 - 0.035 13.9 1.0 1 9.3 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 AFI85656.1 - 0.42 11.2 4.4 0.6 10.7 0.5 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Complex1_51K PF01512.17 AFI85657.1 - 1e-47 161.8 0.0 1.4e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AFI85657.1 - 2.2e-32 111.0 0.1 7.9e-32 109.2 0.0 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AFI85657.1 - 1.7e-14 53.4 0.2 3.7e-14 52.3 0.2 1.6 1 0 0 1 1 1 1 SLBB domain 2Fe-2S_thioredx PF01257.19 AFI85658.1 - 3.7e-55 185.8 0.0 4.2e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Tat PF00539.18 AFI85658.1 - 0.22 11.7 0.8 1.1 9.5 0.2 2.0 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) Complex1_49kDa PF00346.19 AFI85659.1 - 1.3e-126 421.3 0.0 1.6e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 AFI85659.1 - 0.00097 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Complex1_30kDa PF00329.19 AFI85660.1 - 1.8e-42 144.8 0.0 4.8e-42 143.4 0.0 1.7 1 1 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q6 PF01058.22 AFI85661.1 - 1.1e-22 80.2 0.1 1.5e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.19 AFI85662.1 - 1.5e-40 137.4 0.8 1.9e-40 137.0 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 EamA PF00892.20 AFI85663.1 - 2.1e-14 53.8 37.2 1.6e-10 41.3 17.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Gcw_chp PF09694.10 AFI85664.1 - 9.4e-22 78.1 7.7 1.3e-21 77.7 7.7 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) EutQ PF06249.12 AFI85666.1 - 4.5e-10 39.5 0.0 5.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 AFI85666.1 - 2.4e-05 24.0 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 AFI85666.1 - 0.0034 17.1 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 AFI85666.1 - 0.004 16.8 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF1175 PF06672.11 AFI85666.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) SpoVS PF04232.12 AFI85666.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) AraC_binding PF02311.19 AFI85666.1 - 0.05 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain PAS_4 PF08448.10 AFI85667.1 - 1e-12 48.2 0.0 1.4e-06 28.5 0.0 3.5 4 1 0 4 4 3 2 PAS fold PAS_9 PF13426.7 AFI85667.1 - 5.2e-09 36.3 0.1 0.0078 16.5 0.0 3.6 3 1 0 3 3 3 2 PAS domain HTH_3 PF01381.22 AFI85667.1 - 2e-08 34.2 0.1 5.4e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix PAS PF00989.25 AFI85667.1 - 1.6e-07 31.3 0.4 0.16 11.9 0.0 4.1 4 1 0 4 4 4 3 PAS fold HTH_19 PF12844.7 AFI85667.1 - 6.9e-07 29.2 0.1 5.6e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain PAS_3 PF08447.12 AFI85667.1 - 5.7e-06 26.5 0.0 0.00047 20.4 0.0 3.3 2 1 0 2 2 2 1 PAS fold HTH_31 PF13560.6 AFI85667.1 - 1.6e-05 25.2 0.0 5.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain PAS_8 PF13188.7 AFI85667.1 - 3.4e-05 23.7 0.0 0.0031 17.5 0.0 3.2 3 0 0 3 3 3 1 PAS domain PAS_6 PF08348.11 AFI85667.1 - 0.00028 20.7 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 YheO-like PAS domain HTH_26 PF13443.6 AFI85667.1 - 0.00038 20.8 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 AFI85667.1 - 0.00072 19.1 0.5 0.037 13.6 0.1 2.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 AFI85667.1 - 0.0022 17.9 0.0 0.18 11.8 0.0 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain PAS_10 PF13596.6 AFI85667.1 - 0.012 16.1 0.5 6.3 7.4 0.0 3.2 3 0 0 3 3 3 0 PAS domain YdaS_antitoxin PF15943.5 AFI85667.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT rve_3 PF13683.6 AFI85668.1 - 1.6e-13 50.2 1.5 1.7e-13 50.1 1.5 1.0 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AFI85668.1 - 0.00039 20.5 0.3 0.00042 20.4 0.3 1.0 1 0 0 1 1 1 1 Integrase core domain Arm-DNA-bind_3 PF13356.6 AFI85669.1 - 3e-20 72.4 0.4 5.9e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 AFI85669.1 - 5.5e-19 68.6 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 AFI85669.1 - 8.3e-05 22.8 0.5 0.0002 21.6 0.0 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_2 PF12167.8 AFI85669.1 - 0.002 18.0 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain DUF2976 PF11190.8 AFI85669.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) SecG PF03840.14 AFI85670.1 - 7.5e-21 74.0 10.0 9e-21 73.7 10.0 1.1 1 0 0 1 1 1 1 Preprotein translocase SecG subunit Saf_2TM PF18303.1 AFI85670.1 - 0.079 12.5 1.1 0.13 11.9 0.4 1.6 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain TIM PF00121.18 AFI85671.1 - 3.8e-80 268.8 0.0 4.4e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PGM_PMM_I PF02878.16 AFI85672.1 - 1.6e-47 160.7 0.0 3.3e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AFI85672.1 - 3.9e-28 97.9 0.1 7.3e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AFI85672.1 - 1.8e-20 73.4 0.0 3.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AFI85672.1 - 2.8e-14 53.1 0.3 7.5e-14 51.7 0.3 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pterin_bind PF00809.22 AFI85673.1 - 1.2e-91 306.7 0.8 1.4e-91 306.5 0.8 1.0 1 0 0 1 1 1 1 Pterin binding enzyme Peptidase_M41 PF01434.18 AFI85674.1 - 1.5e-73 246.8 0.2 2.2e-73 246.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AFI85674.1 - 9.7e-46 155.5 0.1 3.4e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 AFI85674.1 - 6.5e-13 49.0 0.3 2.9e-12 46.9 0.2 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 AFI85674.1 - 1.9e-12 46.7 0.0 3.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 AFI85674.1 - 2.1e-05 23.9 0.0 4.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 AFI85674.1 - 6.1e-05 23.0 0.0 0.0003 20.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AFI85674.1 - 0.0016 18.2 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 AFI85674.1 - 0.0019 18.3 0.0 0.039 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AFI85674.1 - 0.0076 16.6 1.7 0.037 14.4 0.4 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 AFI85674.1 - 0.0083 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AFI85674.1 - 0.012 15.0 0.2 0.025 14.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AFI85674.1 - 0.015 15.5 0.2 1 9.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AFI85674.1 - 0.02 14.6 0.1 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 AFI85674.1 - 0.034 13.4 0.5 0.067 12.5 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin FtsJ PF01728.19 AFI85675.1 - 1.3e-53 181.7 0.0 1.6e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 AFI85675.1 - 0.0012 18.7 0.7 0.15 11.9 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI85675.1 - 0.033 14.9 0.2 0.27 12.0 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF4149 PF13664.6 AFI85676.1 - 2.9e-14 53.2 7.2 2.9e-14 53.2 7.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Wzy_C PF04932.15 AFI85676.1 - 3.7 7.2 14.3 11 5.6 13.8 2.0 1 1 0 1 1 1 0 O-Antigen ligase GreA_GreB_N PF03449.15 AFI85677.1 - 8.3e-31 106.0 0.5 1.2e-30 105.4 0.5 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AFI85677.1 - 4e-27 93.9 0.1 5.5e-27 93.5 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF1843 PF08898.10 AFI85677.1 - 0.044 14.3 0.4 0.1 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Pox_A_type_inc PF04508.12 AFI85677.1 - 0.12 12.3 0.3 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CPSase_L_D2 PF02786.17 AFI85678.1 - 1.3e-109 364.6 0.1 2.2e-73 246.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AFI85678.1 - 1.8e-40 138.0 0.0 3.8e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AFI85678.1 - 2.2e-19 69.4 0.2 1.5e-18 66.8 0.2 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 AFI85678.1 - 8e-14 51.6 0.0 8e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 AFI85678.1 - 2.5e-10 40.2 0.0 6.7e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 AFI85678.1 - 5.9e-10 39.0 0.0 0.00026 20.6 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AFI85678.1 - 2.1e-09 37.6 0.1 3.2e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_4 PF13535.6 AFI85678.1 - 8.3e-08 32.0 0.2 8.6e-05 22.2 0.1 4.1 3 2 0 3 3 3 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AFI85678.1 - 1e-05 25.1 0.0 0.12 11.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CoA_binding_2 PF13380.6 AFI85678.1 - 0.0027 18.2 0.0 1.9 9.0 0.0 3.2 2 1 0 2 2 2 1 CoA binding domain B12-binding PF02310.19 AFI85678.1 - 0.034 14.2 0.0 18 5.4 0.0 3.1 2 1 0 2 2 2 0 B12 binding domain ATP-grasp_2 PF08442.10 AFI85678.1 - 0.05 13.2 0.0 4.5 6.8 0.0 3.1 2 1 0 2 2 2 0 ATP-grasp domain CPSase_sm_chain PF00988.22 AFI85679.1 - 1.3e-53 180.2 0.0 2e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AFI85679.1 - 5.1e-50 169.9 0.0 7.7e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AFI85679.1 - 1.2e-06 28.5 0.7 2.5e-05 24.2 0.7 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AFI85679.1 - 0.018 14.9 0.0 0.043 13.6 0.0 1.6 2 0 0 2 2 2 0 DJ-1/PfpI family ALAD PF00490.21 AFI85680.1 - 7e-138 459.1 0.0 7.9e-138 458.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AP_endonuc_2 PF01261.24 AFI85680.1 - 0.0078 15.7 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.11 AFI85681.1 - 1.8e-25 89.0 0.0 2.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AFI85681.1 - 7.7e-11 41.6 0.1 1.4e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AFI85681.1 - 2.7e-09 37.2 0.0 5.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase LTXXQ PF07813.12 AFI85682.1 - 3.4e-09 37.3 8.2 4.8e-09 36.9 8.2 1.2 1 0 0 1 1 1 1 LTXXQ motif family protein Metal_resist PF13801.6 AFI85682.1 - 0.00022 21.4 6.6 0.00025 21.2 0.7 2.1 1 1 1 2 2 2 1 Heavy-metal resistance DUF3945 PF13101.6 AFI85682.1 - 0.077 12.7 1.8 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) Response_reg PF00072.24 AFI85683.1 - 7.4e-29 100.2 0.3 1.4e-28 99.3 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AFI85683.1 - 1.4e-21 76.3 0.1 3e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AFI85684.1 - 5.6e-20 71.9 0.0 1.4e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AFI85684.1 - 4e-14 52.4 1.5 4e-14 52.4 1.5 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AFI85684.1 - 1.3e-10 41.5 0.0 3.9e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 AFI85684.1 - 9.1e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase p12I PF12233.8 AFI85684.1 - 0.0012 19.4 1.9 0.0023 18.4 0.5 2.0 2 0 0 2 2 2 1 Human adult T cell leukemia/lymphoma virus protein DUF948 PF06103.11 AFI85684.1 - 0.0074 16.5 0.0 2.1 8.7 0.0 2.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Trehalase_Ca-bi PF07492.11 AFI85684.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain AbfS_sensor PF18225.1 AFI85684.1 - 0.045 13.7 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain HisKA_3 PF07730.13 AFI85684.1 - 0.063 13.8 0.7 0.24 11.9 0.7 2.1 1 0 0 1 1 1 0 Histidine kinase HATPase_c_2 PF13581.6 AFI85684.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AFI85684.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Sod_Cu PF00080.20 AFI85685.1 - 1.2e-30 106.6 0.6 1.4e-30 106.3 0.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ACR_tran PF00873.19 AFI85686.1 - 0 1102.1 9.2 0 1101.9 9.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AFI85686.1 - 6.3e-17 61.5 28.5 4.8e-11 42.2 9.9 2.6 2 0 0 2 2 2 2 MMPL family Patched PF02460.18 AFI85686.1 - 0.00051 18.3 11.1 0.00051 18.3 11.1 2.1 2 0 0 2 2 2 1 Patched family SecD_SecF PF02355.16 AFI85686.1 - 0.021 14.2 28.6 0.0082 15.5 16.1 2.6 2 0 0 2 2 2 0 Protein export membrane protein HlyD_D23 PF16576.5 AFI85687.1 - 3.7e-21 75.4 0.1 6.9e-21 74.5 0.1 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AFI85687.1 - 3.1e-15 55.7 0.1 2.1e-12 46.7 0.0 2.9 2 1 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AFI85687.1 - 3.4e-14 53.4 0.2 1.4e-08 35.4 0.0 3.4 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AFI85687.1 - 2e-05 24.3 0.1 0.002 17.9 0.0 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD PF00529.20 AFI85687.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS MarR PF01047.22 AFI85688.1 - 2e-09 37.2 0.0 7e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AFI85688.1 - 2.6e-09 37.4 0.0 1.2e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AFI85688.1 - 1.5e-08 34.4 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 AFI85688.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix HxlR PF01638.17 AFI85688.1 - 0.0035 17.1 0.1 0.012 15.4 0.0 1.8 1 1 1 2 2 2 1 HxlR-like helix-turn-helix PadR PF03551.14 AFI85688.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AFI85688.1 - 0.0079 16.4 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AFI85688.1 - 0.0089 16.0 1.6 1.7 8.7 0.2 2.5 1 1 1 2 2 2 2 Crp-like helix-turn-helix domain SecA_PP_bind PF01043.20 AFI85688.1 - 0.014 16.0 0.2 0.38 11.4 0.1 2.1 2 0 0 2 2 2 0 SecA preprotein cross-linking domain B-block_TFIIIC PF04182.12 AFI85688.1 - 0.018 15.2 0.1 0.044 14.0 0.0 1.7 1 1 0 2 2 2 0 B-block binding subunit of TFIIIC DUF4364 PF14277.6 AFI85688.1 - 0.029 14.1 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Rrf2 PF02082.20 AFI85688.1 - 0.074 13.4 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator TrmB PF01978.19 AFI85688.1 - 0.084 12.8 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PspB PF06667.12 AFI85688.1 - 0.87 9.7 4.6 8.1 6.6 0.1 3.1 2 1 1 3 3 3 0 Phage shock protein B ZapA PF05164.13 AFI85689.1 - 1.6e-24 86.1 1.2 2e-24 85.9 1.2 1.1 1 0 0 1 1 1 1 Cell division protein ZapA CALCOCO1 PF07888.11 AFI85690.1 - 0.0037 16.2 7.4 0.0042 16.0 7.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like NRBF2 PF08961.10 AFI85690.1 - 0.061 12.9 3.2 0.069 12.8 2.9 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator LprI PF07007.12 AFI85690.1 - 0.074 13.7 3.9 0.1 13.3 3.9 1.2 1 0 0 1 1 1 0 Lysozyme inhibitor LprI TSC22 PF01166.18 AFI85690.1 - 0.077 13.3 9.1 0.15 12.4 2.0 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 AFI85690.1 - 0.079 13.4 11.7 0.25 11.8 11.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 AFI85690.1 - 0.42 11.3 4.7 0.74 10.5 4.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA DUF5595 PF18077.1 AFI85690.1 - 1.1 9.3 5.6 2.5 8.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DivIC PF04977.15 AFI85690.1 - 4.3 7.2 9.4 4.1 7.2 6.6 1.9 1 1 1 2 2 2 0 Septum formation initiator UPF0149 PF03695.13 AFI85691.1 - 6e-26 91.8 0.4 7.1e-26 91.5 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) Peptidase_M24 PF00557.24 AFI85692.1 - 3.1e-68 229.6 0.1 5e-68 228.9 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 AFI85692.1 - 2.8e-37 127.2 0.0 3.2e-36 123.8 0.0 2.5 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 AFI85692.1 - 0.004 17.8 0.0 0.0087 16.7 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF1582 PF07621.11 AFI85692.1 - 0.22 11.5 0.1 0.44 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) FAD_binding_3 PF01494.19 AFI85693.1 - 2e-34 119.4 0.1 2.3e-34 119.2 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AFI85693.1 - 2.8e-07 29.9 0.1 0.026 13.6 0.1 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 AFI85693.1 - 5.1e-07 29.6 0.1 8.8e-07 28.8 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AFI85693.1 - 1.1e-05 24.8 0.0 0.0026 17.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 AFI85693.1 - 6.4e-05 22.1 0.0 0.00017 20.8 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 AFI85693.1 - 0.00016 22.1 0.1 0.00059 20.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AFI85693.1 - 0.0004 20.6 0.0 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AFI85693.1 - 0.00042 19.5 0.3 0.0009 18.4 0.3 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 AFI85693.1 - 0.00082 18.3 0.3 0.58 8.9 0.0 2.5 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 AFI85693.1 - 0.0016 17.7 0.1 1.3 8.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AFI85693.1 - 0.0022 17.2 1.3 0.025 13.7 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain DUF5372 PF17342.2 AFI85693.1 - 0.008 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5372) FAD_binding_3 PF01494.19 AFI85694.1 - 1.6e-27 96.7 0.2 3.2e-27 95.7 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 AFI85694.1 - 4.3e-09 35.7 0.2 0.0027 16.6 0.1 2.5 2 1 0 2 2 2 2 Tryptophan halogenase SE PF08491.10 AFI85694.1 - 1.6e-08 33.9 0.0 5.3e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 AFI85694.1 - 1.1e-05 25.3 0.6 0.0002 21.0 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AFI85694.1 - 2e-05 23.8 2.8 0.036 13.1 0.1 3.0 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AFI85694.1 - 0.00026 20.3 0.1 0.00057 19.2 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AFI85694.1 - 0.00028 21.1 0.2 0.0008 19.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 AFI85694.1 - 0.00049 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Sacchrp_dh_NADP PF03435.18 AFI85694.1 - 0.0045 17.2 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 AFI85694.1 - 0.018 15.0 0.1 0.59 10.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 AFI85694.1 - 0.11 11.5 0.2 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_72 PF03198.14 AFI85695.1 - 0.096 11.9 0.2 0.17 11.1 0.2 1.4 1 1 0 1 1 1 0 Glucanosyltransferase DEAD PF00270.29 AFI85697.1 - 6.3e-45 153.1 0.0 1.3e-44 152.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFI85697.1 - 6.9e-32 110.1 0.0 3.1e-28 98.3 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 AFI85697.1 - 3.9e-06 27.0 0.0 9.3e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 AFI85697.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.6 AFI85697.1 - 0.1 12.4 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.6 AFI85697.1 - 0.35 10.2 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Thioredoxin PF00085.20 AFI85698.1 - 3.9e-33 113.5 0.0 4.4e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AFI85698.1 - 1.3e-07 32.0 0.1 1.4e-06 28.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AFI85698.1 - 3.3e-05 24.1 0.0 0.0023 18.2 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 AFI85698.1 - 0.00018 21.3 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 AFI85698.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AFI85698.1 - 0.0026 17.9 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 AFI85698.1 - 0.02 14.9 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain DUF836 PF05768.14 AFI85698.1 - 0.078 13.4 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.21 AFI85698.1 - 0.086 12.8 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 AFI85698.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family UvrD_C PF13361.6 AFI85699.1 - 5.2e-76 256.3 0.0 1.4e-75 254.9 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AFI85699.1 - 9e-72 242.2 0.0 1.1e-70 238.7 0.0 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AFI85699.1 - 2e-31 109.3 0.1 1.2e-30 106.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 AFI85699.1 - 2.7e-10 39.9 0.0 1.1e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AFI85699.1 - 1e-07 31.9 0.5 0.0016 18.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 AFI85699.1 - 7.4e-05 22.6 0.0 0.073 12.8 0.0 3.3 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 AFI85699.1 - 0.00045 19.9 0.0 1.2 8.7 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 AFI85699.1 - 0.00088 19.1 0.1 0.0028 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Exonuc_V_gamma PF04257.14 AFI85699.1 - 0.0063 14.8 1.3 0.01 14.1 0.2 1.8 2 1 0 2 2 2 1 Exodeoxyribonuclease V, gamma subunit DctP PF03480.13 AFI85700.1 - 4e-60 203.6 0.0 4.7e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Cellulase PF00150.18 AFI85701.1 - 0.039 13.4 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Ntox33 PF15533.6 AFI85701.1 - 0.086 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 33 Toluene_X PF03349.16 AFI85701.1 - 0.15 10.6 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) DUF411 PF04214.13 AFI85702.1 - 2.1e-31 107.7 0.4 3.4e-31 107.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF Thioredoxin_4 PF13462.6 AFI85702.1 - 0.028 14.6 2.1 2.1 8.5 1.1 2.2 1 1 1 2 2 2 0 Thioredoxin EamA PF00892.20 AFI85703.1 - 7.9e-15 55.2 36.4 1.6e-11 44.5 17.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AFI85703.1 - 8.3e-05 22.1 6.5 8.3e-05 22.1 6.5 1.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family SLC35F PF06027.12 AFI85703.1 - 0.0016 18.1 6.8 0.0016 18.1 6.8 2.0 2 0 0 2 2 2 1 Solute carrier family 35 DEAD PF00270.29 AFI85704.1 - 1.1e-44 152.3 0.1 1.8e-44 151.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AFI85704.1 - 6.4e-10 39.3 0.0 1.4e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AFI85704.1 - 4.1e-06 27.2 0.1 6.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI85704.1 - 8.1e-05 22.9 0.0 0.00022 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AFI85704.1 - 8.8e-05 22.3 0.1 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain VEK-30 PF12107.8 AFI85704.1 - 0.00093 19.0 1.3 0.002 17.9 1.3 1.6 1 0 0 1 1 1 1 Plasminogen (Pg) ligand in fibrinolytic pathway UTP25 PF06862.12 AFI85704.1 - 0.0011 17.9 0.2 0.047 12.5 0.1 2.1 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_11 PF13086.6 AFI85704.1 - 0.0015 18.4 0.2 0.24 11.1 0.0 2.2 1 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 AFI85704.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 AFI85704.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 1 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 AFI85704.1 - 0.082 12.9 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 AFI85704.1 - 0.099 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_25 PF13481.6 AFI85704.1 - 0.17 11.5 0.5 0.52 9.9 0.5 1.8 1 1 0 1 1 1 0 AAA domain DUF2986 PF11661.8 AFI85705.1 - 0.02 15.4 8.6 0.024 15.2 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) PEPcase PF00311.17 AFI85706.1 - 1.3e-271 903.3 0.1 1.5e-271 903.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 AFI85706.1 - 9.5e-05 21.1 0.0 0.00017 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PulA_N1 PF17999.1 AFI85706.1 - 0.13 13.1 0.0 0.6 10.9 0.0 2.2 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Glyco_transf_5 PF08323.11 AFI85707.1 - 1.5e-77 260.6 0.0 5.2e-77 258.8 0.0 1.8 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AFI85707.1 - 5.4e-14 52.1 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AFI85707.1 - 5.7e-09 36.2 0.0 1.9e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AFI85707.1 - 1.4e-07 32.1 0.1 2.5e-06 28.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AFI85707.1 - 5.3e-07 30.1 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 G6PD_C PF02781.16 AFI85708.1 - 7.4e-114 379.8 0.0 9.3e-114 379.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AFI85708.1 - 1.4e-56 191.9 0.0 2.6e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain PS_Dcarbxylase PF02666.15 AFI85709.1 - 1.3e-61 207.6 0.0 1.5e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase FliL PF03748.14 AFI85710.1 - 1.8e-18 67.0 0.3 2.6e-18 66.5 0.3 1.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL ParBc_2 PF08857.11 AFI85710.1 - 0.079 13.0 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Putative ParB-like nuclease FliL PF03748.14 AFI85711.1 - 6.5e-21 74.9 0.6 9.4e-21 74.3 0.6 1.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL DUF4064 PF13273.6 AFI85711.1 - 0.0045 17.2 0.4 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Baculo_VP91_N PF08475.10 AFI85711.1 - 0.031 14.0 0.4 0.082 12.6 0.1 1.8 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal TrbE PF11100.8 AFI85711.1 - 0.074 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TrbE FliM PF02154.15 AFI85712.1 - 1.9e-72 243.2 0.1 3e-72 242.5 0.1 1.3 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AFI85712.1 - 3.1e-18 65.6 0.0 6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliMN_C PF01052.20 AFI85713.1 - 2.3e-25 88.4 1.4 3e-25 88.0 1.4 1.2 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliN_N PF16973.5 AFI85713.1 - 0.39 10.6 21.2 1.9 8.4 8.6 2.3 1 1 1 2 2 2 0 Flagellar motor switch protein FliN N-terminal DUF802 PF05650.11 AFI85713.1 - 9.7 6.7 11.8 4.3 7.9 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF802) FliO PF04347.13 AFI85714.1 - 1.5e-21 76.5 0.1 2.1e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO DUF986 PF06173.12 AFI85714.1 - 0.047 13.8 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF986) DUF5383 PF17355.2 AFI85714.1 - 0.084 13.2 0.4 0.16 12.4 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) TMEMspv1-c74-12 PF11044.8 AFI85714.1 - 0.1 12.6 1.8 0.2 11.6 1.8 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein FliP PF00813.20 AFI85715.1 - 6.1e-80 267.6 17.3 7.5e-80 267.3 17.3 1.1 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 AFI85716.1 - 6.9e-26 90.0 16.2 7.9e-26 89.8 16.2 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 TM_helix PF05552.12 AFI85716.1 - 0.043 13.8 1.0 0.043 13.8 1.0 2.7 1 1 1 2 2 2 0 Conserved TM helix FtsX PF02687.21 AFI85716.1 - 0.31 11.5 10.7 0.93 10.0 10.7 1.7 1 1 0 1 1 1 0 FtsX-like permease family Anoctamin PF04547.12 AFI85716.1 - 1.8 7.3 5.8 1.9 7.2 5.8 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel Bac_export_1 PF01311.20 AFI85717.1 - 5.7e-68 228.9 33.7 6.6e-68 228.7 33.7 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 AFI85718.1 - 1.3e-119 399.3 0.4 1.5e-119 399.1 0.4 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Phage_Gp23 PF10669.9 AFI85718.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MttA_Hcf106 PF02416.16 AFI85718.1 - 0.2 11.0 3.0 0.15 11.4 0.4 2.1 2 0 0 2 2 2 0 mttA/Hcf106 family FHIPEP PF00771.20 AFI85719.1 - 9e-274 910.0 1.3 1e-273 909.8 1.3 1.0 1 0 0 1 1 1 1 FHIPEP family SRP54 PF00448.22 AFI85720.1 - 3.2e-37 128.1 0.0 7.1e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AFI85720.1 - 5.4e-07 30.0 0.2 5.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 AFI85720.1 - 8.5e-05 22.0 0.1 0.00021 20.7 0.1 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 AFI85720.1 - 0.00023 20.9 0.4 0.064 13.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 AFI85720.1 - 0.00034 20.2 3.8 0.0005 19.7 0.8 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AFI85720.1 - 0.00052 20.5 3.0 0.00097 19.7 0.6 2.4 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 AFI85720.1 - 0.00092 19.6 0.1 0.0021 18.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AFI85720.1 - 0.0021 18.1 0.0 0.0062 16.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AFI85720.1 - 0.0029 17.3 0.8 0.0086 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AFI85720.1 - 0.0033 17.7 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AFI85720.1 - 0.0061 16.6 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 AFI85720.1 - 0.0064 16.9 0.1 0.013 15.9 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AFI85720.1 - 0.015 15.2 0.3 0.061 13.2 0.1 2.1 2 1 0 2 2 1 0 RsgA GTPase NTPase_1 PF03266.15 AFI85720.1 - 0.016 15.1 0.2 0.042 13.8 0.1 1.7 2 0 0 2 2 1 0 NTPase AAA_18 PF13238.6 AFI85720.1 - 0.025 15.1 0.1 0.055 14.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 AFI85720.1 - 0.035 13.6 0.5 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 AFI85720.1 - 0.037 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 AFI85720.1 - 0.041 13.9 1.0 0.25 11.4 1.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 AFI85720.1 - 0.05 13.2 0.3 0.12 11.9 0.1 1.9 2 1 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 AFI85720.1 - 0.075 12.9 0.1 0.77 9.7 0.1 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 AFI85720.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 AFI85720.1 - 0.086 12.8 0.2 0.55 10.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 AFI85720.1 - 0.091 13.2 0.1 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AFI85720.1 - 0.1 12.6 0.2 0.58 10.2 0.2 2.1 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_binding_1 PF01035.20 AFI85720.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF87 PF01935.17 AFI85720.1 - 0.11 12.6 0.3 0.33 11.0 0.3 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 AFI85720.1 - 0.17 12.2 1.9 0.38 11.1 1.8 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AFI85720.1 - 0.17 11.6 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AFI85720.1 - 0.18 12.3 0.2 0.33 11.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AFI85720.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 AFI85721.1 - 8.3e-24 84.4 2.4 1.8e-23 83.3 2.4 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AFI85721.1 - 1.2e-18 67.4 0.0 2.2e-18 66.6 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AFI85721.1 - 4e-18 66.0 0.3 5.7e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 AFI85721.1 - 3.9e-15 56.0 0.4 3e-14 53.1 0.4 2.1 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 AFI85721.1 - 3.7e-08 33.1 0.1 7e-08 32.2 0.1 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AFI85721.1 - 3.1e-06 26.7 1.2 7.6e-06 25.4 1.2 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AFI85721.1 - 9.2e-06 25.1 1.9 9.2e-06 25.1 1.9 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 AFI85721.1 - 0.00061 19.2 0.3 0.0011 18.4 0.3 1.4 1 0 0 1 1 1 1 VirC1 protein AAA_24 PF13479.6 AFI85721.1 - 0.01 15.6 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 AFI85721.1 - 0.041 13.7 0.6 0.28 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AFI85721.1 - 0.045 13.3 0.3 0.096 12.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AFI85721.1 - 0.072 12.8 0.3 0.18 11.5 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CLP1_P PF16575.5 AFI85721.1 - 0.13 12.1 0.1 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 AFI85721.1 - 0.17 11.8 0.8 0.63 9.9 0.1 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma70_r4 PF04545.16 AFI85722.1 - 1.2e-17 63.1 0.4 3.1e-17 61.8 0.4 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AFI85722.1 - 6.4e-17 61.1 0.0 1.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 AFI85722.1 - 6.3e-15 55.0 0.7 2.1e-13 50.2 0.1 2.4 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 AFI85722.1 - 2e-08 33.8 0.9 9.2e-08 31.7 0.2 2.3 3 0 0 3 3 3 1 Sigma-70, region 4 UPF0122 PF04297.14 AFI85722.1 - 0.00041 20.5 0.1 0.0097 16.1 0.0 2.8 1 1 2 3 3 3 1 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.7 AFI85722.1 - 0.0014 18.4 0.1 0.017 15.0 0.0 2.7 3 0 0 3 3 3 1 MarR family HTH_23 PF13384.6 AFI85722.1 - 0.0018 18.0 0.2 0.0083 15.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.22 AFI85722.1 - 0.0053 16.7 0.0 0.019 14.9 0.0 2.0 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 AFI85722.1 - 0.066 13.1 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain UPF0147 PF03685.13 AFI85722.1 - 0.099 12.7 0.1 0.3 11.2 0.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0147) Tautomerase_2 PF14552.6 AFI85722.1 - 0.12 12.5 0.1 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Tautomerase enzyme Phage_terminase PF10668.9 AFI85722.1 - 0.12 12.4 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Phage terminase small subunit Response_reg PF00072.24 AFI85723.1 - 8.5e-30 103.2 0.1 9.6e-30 103.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Glycos_transf_1 PF00534.20 AFI85723.1 - 0.0075 15.8 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 CheZ PF04344.13 AFI85724.1 - 1.1e-73 247.5 3.7 1.7e-73 246.9 3.7 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ H-kinase_dim PF02895.14 AFI85724.1 - 0.014 15.8 3.2 2.1 8.8 0.1 3.0 2 1 1 3 3 3 0 Signal transducing histidine kinase, homodimeric domain CAMP_factor PF07373.11 AFI85724.1 - 0.021 14.4 1.4 0.045 13.4 1.4 1.6 1 0 0 1 1 1 0 CAMP factor (Cfa) Ran-binding PF05508.11 AFI85724.1 - 0.032 13.2 2.5 0.035 13.1 0.4 2.0 1 1 2 3 3 3 0 RanGTP-binding protein DUF3080 PF11279.8 AFI85724.1 - 0.061 12.5 3.4 1 8.5 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) Exonuc_VII_L PF02601.15 AFI85724.1 - 0.12 11.9 4.3 0.15 11.6 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 AFI85724.1 - 1.8 9.3 6.3 3.4 8.4 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) CheW PF01584.19 AFI85725.1 - 8.6e-25 87.0 0.1 1.5e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 CheW-like domain HATPase_c PF02518.26 AFI85725.1 - 2.9e-17 63.2 0.0 6.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 AFI85725.1 - 9.2e-17 61.1 2.7 1.4e-16 60.5 0.2 2.7 3 0 0 3 3 3 1 Hpt domain H-kinase_dim PF02895.14 AFI85725.1 - 1.5e-14 54.1 2.2 4.6e-14 52.6 2.2 1.9 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain SHOCT PF09851.9 AFI85725.1 - 0.0004 20.0 3.7 0.72 9.7 0.0 2.7 2 0 0 2 2 2 2 Short C-terminal domain HATPase_c_3 PF13589.6 AFI85725.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AFI85725.1 - 0.096 12.6 0.8 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain CheB_methylest PF01339.17 AFI85726.1 - 1.3e-56 191.0 0.1 4.9e-56 189.1 0.1 1.9 3 0 0 3 3 3 1 CheB methylesterase Response_reg PF00072.24 AFI85726.1 - 7.6e-24 84.0 0.0 1.5e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain MotA_ExbB PF01618.16 AFI85727.1 - 5.5e-28 97.3 0.8 5.5e-28 97.3 0.8 1.8 2 0 0 2 2 2 1 MotA/TolQ/ExbB proton channel family LPG_synthase_TM PF03706.13 AFI85727.1 - 0.0052 16.4 3.3 0.36 10.3 0.9 2.1 2 0 0 2 2 2 2 Lysylphosphatidylglycerol synthase TM region MotB_plug PF13677.6 AFI85728.1 - 2.3e-22 78.3 0.0 5.6e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AFI85728.1 - 3.7e-17 62.5 0.0 9e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 OmpA family AAA_31 PF13614.6 AFI85729.1 - 1.2e-47 162.1 0.0 1.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AFI85729.1 - 1.1e-20 74.0 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AFI85729.1 - 2.4e-12 46.9 0.0 9.3e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AFI85729.1 - 7.7e-12 45.2 0.2 1.1e-11 44.7 0.2 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AFI85729.1 - 3.4e-10 39.6 0.0 9.8e-09 34.8 0.0 2.1 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 AFI85729.1 - 1.1e-08 34.7 0.1 2.8e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 ATPase MipZ ATP_bind_1 PF03029.17 AFI85729.1 - 0.00033 20.5 0.1 0.0053 16.6 0.1 2.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein VirC1 PF07015.11 AFI85729.1 - 0.0014 18.0 0.1 0.0059 15.9 0.0 1.9 2 1 0 2 2 2 1 VirC1 protein Fer4_NifH PF00142.18 AFI85729.1 - 0.004 16.7 0.0 0.024 14.1 0.0 2.1 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 AFI85729.1 - 0.0095 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 AFI85729.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SRP54 PF00448.22 AFI85729.1 - 0.016 14.9 0.3 0.058 13.0 0.2 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.29 AFI85729.1 - 0.088 13.2 0.0 1.4 9.3 0.0 2.4 1 1 2 3 3 3 0 ATPase family associated with various cellular activities (AAA) CLP1_P PF16575.5 AFI85729.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HSBP1 PF06825.12 AFI85729.1 - 0.6 10.0 4.0 1.4 8.9 0.2 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CheW PF01584.19 AFI85730.1 - 3.7e-13 49.3 0.0 5.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AFI85731.1 - 9.1e-39 132.3 0.8 1e-38 132.1 0.8 1.0 1 0 0 1 1 1 1 CheW-like domain DUF2802 PF10975.8 AFI85733.1 - 8.6e-22 77.0 0.8 8.6e-22 77.0 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) DUF2681 PF10883.8 AFI85733.1 - 0.00032 21.1 1.3 0.021 15.2 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2681) Asparaginase_II PF06089.12 AFI85733.1 - 0.014 14.4 0.1 0.019 14.0 0.1 1.0 1 0 0 1 1 1 0 L-asparaginase II Phage_X PF05155.15 AFI85733.1 - 0.064 13.7 0.2 0.14 12.6 0.0 1.6 2 0 0 2 2 2 0 Phage X family Bac_export_2 PF01312.19 AFI85734.1 - 8.4e-18 64.7 1.0 1e-17 64.4 1.0 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family LPD7 PF18821.1 AFI85734.1 - 0.079 13.1 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 TolA PF06519.11 AFI85734.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 TolA C-terminal Flg_hook PF02120.16 AFI85735.1 - 2.6e-14 52.8 1.9 2.6e-14 52.8 1.9 3.7 3 1 0 3 3 3 1 Flagellar hook-length control protein FliK HpaP PF09483.10 AFI85735.1 - 0.0016 18.6 7.8 0.013 15.7 0.9 2.8 2 0 0 2 2 2 2 Type III secretion protein (HpaP) Pentapeptide PF00805.22 AFI85736.1 - 1e-25 89.0 24.9 1.9e-10 40.2 1.4 3.6 2 1 3 5 5 5 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AFI85736.1 - 3.4e-13 49.5 0.0 4.8e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AFI85736.1 - 5.1e-05 23.3 0.0 0.0031 17.7 0.0 2.7 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) DUF525 PF04379.14 AFI85737.1 - 8.9e-33 112.4 0.0 1.1e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 ApaG domain DUF4354 PF14263.6 AFI85737.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4354) Glucokinase PF02685.16 AFI85738.1 - 2e-102 342.4 0.4 2.3e-102 342.2 0.4 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 AFI85738.1 - 3.9e-05 23.3 0.1 0.0033 16.9 0.1 2.3 2 1 0 2 2 2 2 ROK family Glucosamine_iso PF01182.20 AFI85739.1 - 1.9e-71 240.6 0.0 2.1e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Reovirus_L2 PF06016.11 AFI85739.1 - 0.032 11.5 0.0 0.039 11.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) OmpH PF03938.14 AFI85739.1 - 0.13 12.6 0.0 4.5 7.6 0.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SIMPL PF04402.14 AFI85740.1 - 2.7e-29 103.1 3.5 3.1e-29 102.9 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Smac_DIABLO PF09057.10 AFI85740.1 - 0.042 13.2 1.9 0.066 12.6 0.1 2.1 2 1 1 3 3 3 0 Second Mitochondria-derived Activator of Caspases RNA_pol_L_2 PF13656.6 AFI85740.1 - 0.066 13.0 0.2 0.23 11.2 0.0 2.0 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain MscS_porin PF12795.7 AFI85740.1 - 0.15 11.6 4.8 0.69 9.4 5.0 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain PALP PF00291.25 AFI85741.1 - 7.7e-82 275.0 0.6 9.4e-82 274.7 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AFI85741.1 - 1.8e-49 165.4 0.1 2e-24 85.2 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Rib_5-P_isom_A PF06026.14 AFI85742.1 - 1e-56 191.2 0.3 1.4e-56 190.8 0.3 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AFI85742.1 - 0.017 15.0 0.6 0.098 12.6 0.0 2.4 3 0 0 3 3 3 0 DeoR C terminal sensor domain MacB_PCD PF12704.7 AFI85743.1 - 5.4e-18 66.1 0.9 5.4e-18 66.1 0.9 2.3 3 1 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 AFI85743.1 - 2.5e-11 43.9 6.0 2.5e-11 43.9 6.0 2.7 3 0 0 3 3 3 1 FtsX-like permease family Phage_r1t_holin PF16945.5 AFI85743.1 - 0.024 14.8 1.1 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin STIMATE PF12400.8 AFI85743.1 - 0.16 12.6 2.8 0.17 12.5 0.4 2.3 2 1 0 2 2 2 0 STIMATE family Trp_oprn_chp PF09534.10 AFI85743.1 - 0.69 9.7 5.0 0.53 10.0 1.7 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pho86 PF11124.8 AFI85743.1 - 3.7 6.9 6.0 1.5 8.2 3.3 1.7 1 1 1 2 2 2 0 Inorganic phosphate transporter Pho86 ABC_tran PF00005.27 AFI85744.1 - 4.8e-34 117.8 0.0 6.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFI85744.1 - 9.2e-07 29.0 0.4 0.017 15.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI85744.1 - 1.8e-06 27.5 0.1 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AFI85744.1 - 0.00073 19.2 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AFI85744.1 - 0.004 17.3 0.0 0.0069 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFI85744.1 - 0.0085 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 AFI85744.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AFI85744.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 AFI85744.1 - 0.024 14.9 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AFI85744.1 - 0.025 14.2 0.1 0.051 13.2 0.1 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AFI85744.1 - 0.034 14.4 1.3 0.37 11.1 1.3 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AFI85744.1 - 0.046 13.8 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 AFI85744.1 - 0.064 13.0 0.2 0.38 10.5 0.1 2.1 2 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AFI85744.1 - 0.087 13.2 4.3 0.69 10.3 4.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AFI85744.1 - 0.14 12.1 0.5 0.33 10.8 0.2 1.8 2 0 0 2 2 2 0 NACHT domain DUF2062 PF09835.9 AFI85745.1 - 7e-44 149.3 14.1 8.1e-44 149.1 14.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF2755 PF10954.8 AFI85745.1 - 0.099 12.6 2.3 0.36 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) Competence PF03772.16 AFI85746.1 - 2.7e-70 236.8 37.3 2.7e-70 236.8 37.3 2.1 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 AFI85746.1 - 9.3e-29 100.2 0.1 9.3e-29 100.2 0.1 5.3 3 1 2 5 5 5 1 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 AFI85746.1 - 1.4e-11 44.8 0.0 2.8e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AFI85746.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain MotA_ExbB PF01618.16 AFI85747.1 - 1.4e-36 125.0 0.9 2e-36 124.6 0.9 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family MlaE PF02405.16 AFI85747.1 - 0.14 11.8 4.8 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Permease MlaE ExbD PF02472.16 AFI85748.1 - 1.5e-30 106.0 0.1 1.7e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR ABC_membrane PF00664.23 AFI85749.1 - 9.4e-51 173.1 11.4 1.3e-50 172.6 11.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AFI85749.1 - 1.7e-33 116.0 0.3 3.4e-33 115.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AFI85749.1 - 3.3e-08 33.2 0.2 1.6e-07 31.0 0.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AFI85749.1 - 3.5e-05 24.2 0.9 0.00015 22.2 0.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AFI85749.1 - 4.7e-05 23.4 0.1 0.0002 21.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase DEAD PF00270.29 AFI85749.1 - 0.00026 20.8 0.2 0.00066 19.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AFI85749.1 - 0.004 17.4 1.7 0.049 13.9 1.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AFI85749.1 - 0.0075 16.0 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AFI85749.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AFI85749.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AFI85749.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit IstB_IS21 PF01695.17 AFI85749.1 - 0.059 13.1 0.2 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 AFI85749.1 - 0.07 12.7 0.4 5.1 6.6 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 AFI85749.1 - 0.13 12.0 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AFI85749.1 - 2.6 8.5 6.7 62 4.0 4.9 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LpxK PF02606.14 AFI85750.1 - 9.5e-116 386.4 0.0 1.1e-115 386.2 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Trm112p PF03966.16 AFI85751.1 - 3.1e-11 43.7 1.3 8.6e-11 42.3 1.3 1.7 1 1 0 1 1 1 1 Trm112p-like protein DUF2318 PF10080.9 AFI85751.1 - 0.00034 20.7 0.2 0.00039 20.5 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) RPA_interact_C PF14768.6 AFI85751.1 - 0.0023 18.5 0.3 0.0023 18.5 0.3 1.1 1 0 0 1 1 1 1 Replication protein A interacting C-terminal TF_Zn_Ribbon PF08271.12 AFI85751.1 - 0.0026 17.2 0.3 0.0032 16.9 0.3 1.4 1 1 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 AFI85751.1 - 0.0065 16.2 0.3 0.0084 15.8 0.3 1.2 1 0 0 1 1 1 1 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 AFI85751.1 - 0.0078 16.2 0.4 0.012 15.6 0.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.12 AFI85751.1 - 0.011 15.8 0.8 0.015 15.5 0.8 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cys_rich_CPCC PF14206.6 AFI85751.1 - 0.053 13.3 0.3 0.055 13.3 0.3 1.2 1 0 0 1 1 1 0 Cysteine-rich CPCC C1_1 PF00130.22 AFI85751.1 - 0.059 13.3 0.3 0.071 13.0 0.3 1.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.6 AFI85751.1 - 0.13 12.7 0.9 0.18 12.2 0.9 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar PhnA_Zn_Ribbon PF08274.12 AFI85751.1 - 0.56 10.2 4.6 0.14 12.1 1.4 1.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CTP_transf_3 PF02348.19 AFI85752.1 - 4.2e-58 196.9 0.0 5.2e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AFI85752.1 - 5.1e-11 43.2 0.8 5.9e-11 43.0 0.8 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AFI85752.1 - 0.00015 21.6 0.1 0.00021 21.1 0.1 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ADH_zinc_N PF00107.26 AFI85752.1 - 0.0047 16.9 0.3 0.012 15.6 0.2 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NTP_transferase PF00483.23 AFI85752.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase RNase_E_G PF10150.9 AFI85754.1 - 1.9e-94 316.1 0.0 2.7e-94 315.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AFI85754.1 - 3.2e-13 49.8 0.6 7.6e-13 48.6 0.2 1.9 2 0 0 2 2 2 1 S1 RNA binding domain PseudoU_synth_2 PF00849.22 AFI85755.1 - 5.6e-30 104.5 0.0 8.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AFI85755.1 - 1.4e-06 27.9 0.7 2.7e-06 27.0 0.7 1.5 1 0 0 1 1 1 1 S4 domain DUF1057 PF06342.12 AFI85755.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) HAD_2 PF13419.6 AFI85756.1 - 2e-32 112.7 0.0 2.3e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AFI85756.1 - 9.9e-15 54.4 0.1 4.6e-14 52.2 0.0 2.1 2 1 1 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 AFI85756.1 - 7.5e-14 52.5 0.0 2.7e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AFI85756.1 - 6.1e-11 43.1 0.1 8.7e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AFI85756.1 - 3e-08 33.7 0.0 0.19 11.5 0.1 3.1 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Peptidase_S49 PF01343.18 AFI85757.1 - 2.4e-34 118.5 0.0 4e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 AFI85757.1 - 0.00026 20.1 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase HDOD PF08668.12 AFI85759.1 - 9.1e-60 201.5 0.0 1.1e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AFI85759.1 - 3.7e-07 30.4 0.2 8.7e-07 29.2 0.2 1.6 1 1 0 1 1 1 1 HD domain TRF PF08558.10 AFI85759.1 - 0.17 11.4 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) ADK PF00406.22 AFI85760.1 - 8.6e-56 188.2 0.0 1e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AFI85760.1 - 9.3e-26 90.9 0.1 2e-25 89.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 AFI85760.1 - 1.8e-16 59.8 1.2 3.9e-16 58.7 1.1 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 AFI85760.1 - 1.4e-07 32.1 0.0 2.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AFI85760.1 - 0.00026 21.1 0.0 0.00072 19.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 AFI85760.1 - 0.0015 18.9 0.1 0.16 12.2 0.0 2.2 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain A2L_zn_ribbon PF08792.10 AFI85760.1 - 0.012 15.3 0.7 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain HypA PF01155.19 AFI85760.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AFI85760.1 - 0.025 14.7 1.5 0.046 13.8 1.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF1451 PF07295.11 AFI85760.1 - 0.037 14.1 1.1 0.068 13.2 1.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain DZR PF12773.7 AFI85760.1 - 0.049 13.7 0.6 0.086 12.9 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon SKI PF01202.22 AFI85760.1 - 0.069 13.3 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase OrfB_Zn_ribbon PF07282.11 AFI85760.1 - 0.11 12.4 0.3 0.19 11.7 0.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1272 PF06906.11 AFI85760.1 - 0.21 11.7 2.0 0.74 10.0 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) YceD PF02620.17 AFI85760.1 - 0.24 11.5 0.7 8.5 6.5 0.6 2.3 1 1 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD zf-ribbon_3 PF13248.6 AFI85760.1 - 0.47 9.9 3.0 3.4 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PfkB PF00294.24 AFI85761.1 - 4.2e-34 118.2 0.0 5e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase YecR PF13992.6 AFI85761.1 - 0.092 13.1 0.0 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 YecR-like lipoprotein Rieske PF00355.26 AFI85762.1 - 8.6e-13 48.1 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Helicase_RecD PF05127.14 AFI85763.1 - 4.3e-54 183.0 0.0 8.1e-54 182.2 0.0 1.5 1 0 0 1 1 1 1 Helicase GNAT_acetyltr_2 PF13718.6 AFI85763.1 - 4.1e-22 78.7 0.0 1.2e-15 57.6 0.0 2.3 1 1 1 2 2 2 2 GNAT acetyltransferase 2 DUF1726 PF08351.11 AFI85763.1 - 1.9e-11 43.7 0.0 6.3e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_3 PF17176.4 AFI85763.1 - 6.9e-09 36.0 5.4 6.9e-09 36.0 5.4 2.3 2 0 0 2 2 1 1 tRNA-binding domain ResIII PF04851.15 AFI85763.1 - 2e-06 27.9 0.1 0.00068 19.7 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Acetyltransf_7 PF13508.7 AFI85763.1 - 0.0001 22.7 0.0 0.00033 21.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_19 PF13245.6 AFI85763.1 - 0.00012 22.4 0.0 0.00031 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AFI85763.1 - 0.00014 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Acetyltransf_1 PF00583.25 AFI85763.1 - 0.00016 21.9 0.0 0.00039 20.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AFI85763.1 - 0.0033 17.3 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AFI85763.1 - 0.0042 17.2 0.0 0.72 9.9 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.6 AFI85763.1 - 0.0059 16.9 0.1 0.02 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain DEAD PF00270.29 AFI85763.1 - 0.007 16.2 0.0 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Acetyltransf_CG PF14542.6 AFI85763.1 - 0.054 13.6 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 AFI85763.1 - 0.09 12.8 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein GP88 PF17338.2 AFI85763.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Gene product 88 AAA_11 PF13086.6 AFI85763.1 - 0.11 12.3 0.1 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 AFI85764.1 - 1.5e-22 79.9 6.2 1.7e-22 79.8 6.2 1.0 1 0 0 1 1 1 1 SlyX LUC7 PF03194.15 AFI85764.1 - 0.006 16.3 1.1 0.0066 16.2 1.1 1.1 1 0 0 1 1 1 1 LUC7 N_terminus PspA_IM30 PF04012.12 AFI85764.1 - 0.0082 15.7 5.2 0.0092 15.6 5.2 1.0 1 0 0 1 1 1 1 PspA/IM30 family TolA_bind_tri PF16331.5 AFI85764.1 - 0.0085 16.1 10.8 0.016 15.3 10.8 1.5 1 1 0 1 1 1 1 TolA binding protein trimerisation ANAPC16 PF17256.2 AFI85764.1 - 0.013 15.9 3.0 0.021 15.2 3.0 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, subunit 16 DASH_Spc19 PF08287.11 AFI85764.1 - 0.027 14.4 0.6 0.029 14.3 0.6 1.1 1 0 0 1 1 1 0 Spc19 HemX PF04375.14 AFI85764.1 - 0.035 13.4 4.0 0.037 13.3 4.0 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DivIC PF04977.15 AFI85764.1 - 0.051 13.4 4.9 0.058 13.2 4.5 1.3 1 1 0 1 1 1 0 Septum formation initiator CLZ PF16526.5 AFI85764.1 - 0.07 13.5 2.9 0.11 12.9 2.9 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_GP20 PF06810.11 AFI85764.1 - 0.087 12.6 1.9 0.092 12.5 1.9 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF16 PF01519.16 AFI85764.1 - 0.093 13.2 4.6 0.1 13.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.11 AFI85764.1 - 0.11 12.8 0.5 0.15 12.4 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Glu-tRNAGln PF02686.15 AFI85764.1 - 0.11 12.8 2.1 2.8 8.3 0.1 2.1 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit ABC_tran_CTD PF16326.5 AFI85764.1 - 0.11 12.7 2.6 0.22 11.8 1.6 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Ran-binding PF05508.11 AFI85764.1 - 0.17 10.8 1.2 0.18 10.7 1.2 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Viral_P18 PF04521.13 AFI85764.1 - 0.18 11.6 0.3 0.21 11.4 0.3 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Nup54 PF13874.6 AFI85764.1 - 0.2 11.8 4.4 0.29 11.3 4.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Hemagglutinin PF00509.18 AFI85764.1 - 0.22 9.9 0.4 0.24 9.7 0.4 1.0 1 0 0 1 1 1 0 Haemagglutinin Met_synt_B12 PF02965.17 AFI85765.1 - 6.3e-132 439.1 0.0 1.7e-131 437.7 0.0 1.7 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 AFI85765.1 - 3.8e-84 282.7 0.0 7.3e-84 281.7 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 AFI85765.1 - 1e-57 195.7 2.2 1.2e-57 195.4 0.9 1.9 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 AFI85765.1 - 1.2e-23 83.3 0.3 1.2e-23 83.3 0.3 3.0 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 AFI85765.1 - 7.7e-21 74.4 0.7 2.4e-20 72.8 0.2 2.2 2 0 0 2 2 2 1 B12 binding domain MtrH PF02007.18 AFI85765.1 - 0.006 15.7 0.4 0.012 14.7 0.4 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit Band_7 PF01145.25 AFI85766.1 - 2.8e-35 121.9 3.9 3.7e-35 121.5 3.9 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AFI85766.1 - 0.0016 18.2 0.3 0.0029 17.3 0.3 1.5 1 1 0 1 1 1 1 SPFH domain-Band 7 family MutS_IV PF05190.18 AFI85766.1 - 0.14 12.5 0.4 0.28 11.6 0.4 1.5 1 0 0 1 1 1 0 MutS family domain IV DUF3139 PF11337.8 AFI85766.1 - 0.2 12.3 1.5 18 6.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) DUF4083 PF13314.6 AFI85766.1 - 0.24 11.3 3.2 0.62 10.1 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) NfeD PF01957.18 AFI85767.1 - 1.3e-14 54.3 0.5 3.8e-14 52.8 0.5 1.8 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding CLP_protease PF00574.23 AFI85767.1 - 0.0063 16.4 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 Clp protease p450 PF00067.22 AFI85769.1 - 3.9e-17 62.2 0.3 3.9e-17 62.2 0.3 1.5 2 0 0 2 2 2 1 Cytochrome P450 DUF2383 PF09537.10 AFI85772.1 - 3.9e-11 43.3 0.0 6.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF892 PF05974.12 AFI85772.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF326 PF03860.16 AFI85773.1 - 2.8e-08 33.5 33.9 6.3e-05 22.8 13.1 4.2 4 1 0 4 4 4 3 Domain of Unknown Function (DUF326) CBS PF00571.28 AFI85774.1 - 1.6e-23 82.9 0.3 1.8e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 CBS domain HK97-gp10_like PF04883.12 AFI85775.1 - 0.15 13.0 0.0 0.17 12.9 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component adh_short_C2 PF13561.6 AFI85776.1 - 5.5e-54 183.2 0.0 7.2e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AFI85776.1 - 2.4e-45 154.4 0.0 2.8e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AFI85776.1 - 0.00013 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AFI85776.1 - 0.0042 16.6 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIP49 PF06068.13 AFI85776.1 - 0.16 11.1 0.1 0.23 10.6 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain MCPsignal PF00015.21 AFI85777.1 - 3.1e-43 147.5 31.5 1.2e-42 145.7 20.3 2.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 AFI85777.1 - 1.8e-17 64.0 0.1 1.8e-17 64.0 0.1 2.6 2 1 0 2 2 2 1 Cache domain HAMP PF00672.25 AFI85777.1 - 2.7e-08 34.1 0.7 1.2e-07 31.9 0.0 2.6 3 0 0 3 3 3 1 HAMP domain Syntaxin_2 PF14523.6 AFI85777.1 - 0.017 15.5 18.6 0.56 10.6 1.0 4.2 1 1 3 4 4 4 0 Syntaxin-like protein Barstar PF01337.18 AFI85777.1 - 0.077 13.0 0.0 1 9.4 0.0 2.8 2 0 0 2 2 2 0 Barstar (barnase inhibitor) DUF2182 PF09948.9 AFI85777.1 - 0.16 11.9 0.9 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) LapA_dom PF06305.11 AFI85777.1 - 4.9 7.1 6.7 8.5 6.3 0.6 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain BLOC1_2 PF10046.9 AFI85777.1 - 8.1 6.8 17.3 7.9 6.9 1.2 4.1 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LEA_2 PF03168.13 AFI85779.1 - 1.7e-07 31.7 0.0 2.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein HMGL-like PF00682.19 AFI85782.1 - 6.7e-77 258.6 0.0 9.5e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AFI85782.1 - 5.4e-27 94.3 1.0 9.6e-27 93.5 1.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Nuc_deoxyri_tr2 PF15891.5 AFI85782.1 - 0.02 15.2 0.0 0.076 13.3 0.0 2.0 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like AsnC_trans_reg PF01037.21 AFI85783.1 - 5.6e-25 87.1 0.1 1.1e-24 86.2 0.0 1.5 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AFI85783.1 - 1.5e-18 66.1 0.6 2.8e-18 65.2 0.2 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AFI85783.1 - 4.9e-15 55.1 0.4 8.3e-15 54.3 0.1 1.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.22 AFI85783.1 - 1.5e-08 34.4 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 AFI85783.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 AFI85783.1 - 0.00012 21.9 0.1 0.00025 21.0 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AFI85783.1 - 0.00027 20.7 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_12 PF08461.10 AFI85783.1 - 0.0017 18.2 0.1 0.004 17.1 0.1 1.6 1 1 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_11 PF08279.12 AFI85783.1 - 0.0021 17.9 0.1 0.0062 16.5 0.1 1.8 2 0 0 2 2 2 1 HTH domain MarR_2 PF12802.7 AFI85783.1 - 0.0035 17.2 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 AFI85783.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AFI85783.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 AFI85783.1 - 0.027 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 AFI85783.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Herpes_UL32 PF06070.11 AFI85783.1 - 0.1 10.3 0.0 0.12 10.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Put_DNA-bind_N PF06971.13 AFI85783.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.8 1 1 0 1 1 1 0 Putative DNA-binding protein N-terminus PPK2 PF03976.14 AFI85784.1 - 2.8e-65 220.1 1.0 6.1e-65 218.9 1.0 1.5 1 1 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) Methyltransf_33 PF10017.9 AFI85785.1 - 1.8e-101 339.4 0.0 2.3e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 AFI85785.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 AFI85785.1 - 0.01 16.5 0.0 0.039 14.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85785.1 - 0.039 14.7 0.1 0.2 12.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain FGE-sulfatase PF03781.16 AFI85787.1 - 4.1e-17 62.6 4.3 7.5e-17 61.8 2.3 2.4 2 1 1 3 3 3 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 AFI85787.1 - 4.9e-07 30.3 3.3 4.8e-06 27.1 2.5 2.7 2 1 0 2 2 2 1 DinB superfamily EAL PF00563.20 AFI85787.1 - 0.061 12.8 0.2 0.098 12.2 0.2 1.3 1 0 0 1 1 1 0 EAL domain Zip PF02535.22 AFI85788.1 - 9.4e-11 41.5 11.3 1.6e-05 24.3 1.1 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4203 PF13886.6 AFI85788.1 - 0.07 12.8 10.8 1 9.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) TctB PF07331.11 AFI85788.1 - 0.25 11.6 11.1 3.6 7.9 9.6 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family SGL PF08450.12 AFI85789.1 - 1.5e-15 57.5 1.0 1.6e-05 24.6 0.0 3.2 2 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 AFI85789.1 - 3.2e-06 26.7 6.4 2.1 8.8 0.0 5.8 6 0 0 6 6 6 2 Two component regulator propeller DUF5074 PF16819.5 AFI85789.1 - 6.9e-06 26.1 0.0 0.16 12.0 0.0 4.3 1 1 2 3 3 3 2 Domain of unknown function (DUF5074) Lactonase PF10282.9 AFI85789.1 - 0.058 12.7 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller VirionAssem_T7 PF11653.8 AFI85789.1 - 0.17 12.4 0.0 7.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein ExoD PF06055.12 AFI85790.1 - 3.8e-50 169.8 10.4 4.2e-50 169.6 10.4 1.0 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD SBF PF01758.16 AFI85791.1 - 1.5e-19 70.4 14.3 1.5e-19 70.4 14.3 2.6 2 1 0 2 2 2 1 Sodium Bile acid symporter family Pox_I3 PF04661.12 AFI85792.1 - 0.018 14.2 0.8 0.018 14.2 0.8 1.1 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein Spore_YhaL PF14147.6 AFI85792.1 - 0.053 13.2 0.4 0.1 12.3 0.4 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL MS_channel PF00924.18 AFI85793.1 - 3.3e-17 62.7 1.4 6.9e-17 61.7 1.4 1.5 1 1 0 1 1 1 1 Mechanosensitive ion channel SpoIISA_toxin PF14171.6 AFI85793.1 - 0.056 13.1 1.3 0.19 11.4 0.6 1.9 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Babuvirus_MP PF07234.11 AFI85793.1 - 1.5 9.0 4.9 5 7.3 0.8 3.0 2 1 1 3 3 3 0 Movement and RNA silencing protein FA_desaturase PF00487.24 AFI85793.1 - 1.8 8.3 3.2 2.9 7.7 3.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase PhoH PF02562.16 AFI85794.1 - 1.4e-54 184.7 0.0 2.2e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 AFI85794.1 - 7.5e-40 136.3 0.0 1.3e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 AFI85794.1 - 2.1e-08 34.1 0.0 5.9e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI85794.1 - 1.9e-06 28.2 0.1 9.8e-06 25.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AFI85794.1 - 0.00044 20.6 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DEAD PF00270.29 AFI85794.1 - 0.012 15.3 0.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.22 AFI85794.1 - 0.049 12.8 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 AFI85794.1 - 0.06 12.6 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 AFI85794.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PilZ PF07238.14 AFI85795.1 - 5.3e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 PilZ domain MbeD_MobD PF04899.12 AFI85795.1 - 0.0091 16.1 0.2 0.022 14.9 0.1 1.6 2 0 0 2 2 2 1 MbeD/MobD like Baculo_PEP_C PF04513.12 AFI85795.1 - 0.041 13.9 2.1 0.065 13.3 2.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dad3 PF08656.10 AFI85795.1 - 0.08 13.0 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad3 GST_N_3 PF13417.6 AFI85796.1 - 6.8e-11 42.4 0.0 2.6e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AFI85796.1 - 6.9e-11 42.0 0.8 1.4e-10 41.0 0.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AFI85796.1 - 4.3e-10 39.8 0.1 1.3e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AFI85796.1 - 3.5e-08 33.6 1.2 5.3e-07 29.8 1.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AFI85796.1 - 4.5e-07 30.0 0.3 1.6e-06 28.3 0.3 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AFI85796.1 - 8.5e-07 29.2 0.1 5.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 AFI85796.1 - 0.029 15.1 0.1 0.057 14.2 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain AAA_26 PF13500.6 AFI85797.1 - 4.4e-43 147.4 0.3 4.9e-43 147.3 0.3 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AFI85797.1 - 9.5e-12 45.1 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 AFI85797.1 - 0.0011 18.9 0.0 0.0079 16.1 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.11 AFI85797.1 - 0.003 16.9 1.2 0.017 14.4 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain Methyltransf_11 PF08241.12 AFI85798.1 - 4.1e-23 81.8 0.0 8e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI85798.1 - 9.8e-20 71.1 0.0 2.8e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AFI85798.1 - 1.2e-13 51.1 0.0 3.4e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AFI85798.1 - 3.7e-13 49.7 0.0 6.9e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AFI85798.1 - 1.3e-11 45.1 0.0 3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AFI85798.1 - 1.5e-09 37.6 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 AFI85798.1 - 2.4e-06 27.6 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 AFI85798.1 - 0.00043 19.7 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain PrmA PF06325.13 AFI85798.1 - 0.006 16.0 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 AFI85798.1 - 0.007 15.8 0.0 0.23 10.9 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_33 PF10017.9 AFI85798.1 - 0.0073 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_29 PF03141.16 AFI85798.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pox_MCEL PF03291.16 AFI85798.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.3 1 1 0 1 1 1 0 mRNA capping enzyme Abhydrolase_6 PF12697.7 AFI85799.1 - 6.7e-25 89.0 0.5 7.8e-25 88.8 0.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AFI85799.1 - 2.2e-22 80.0 0.0 3.3e-21 76.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AFI85799.1 - 1e-12 47.8 0.0 5.2e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AFI85799.1 - 2.6e-06 27.7 0.1 6e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 AFI85799.1 - 0.0001 22.1 0.0 0.36 10.6 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 AFI85799.1 - 0.0079 15.8 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.14 AFI85799.1 - 0.011 14.5 0.0 0.014 14.1 0.0 1.5 1 1 0 1 1 1 0 Ndr family UPF0227 PF05728.12 AFI85799.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 AFI85799.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase HTH_psq PF05225.16 AFI85799.1 - 0.17 11.6 0.4 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Aminotran_1_2 PF00155.21 AFI85800.1 - 1.1e-59 202.5 0.0 1.2e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AFI85800.1 - 0.00036 20.0 1.5 0.13 11.6 0.1 3.2 3 1 1 4 4 4 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AFI85800.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AFI85800.1 - 0.027 13.0 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AFI85800.1 - 0.033 13.5 0.2 0.76 9.0 0.1 2.4 2 1 0 2 2 2 0 Beta-eliminating lyase BATS PF06968.13 AFI85801.1 - 9.2e-20 70.6 0.1 2.2e-18 66.2 0.0 2.7 3 0 0 3 3 3 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AFI85801.1 - 3.2e-16 60.2 0.0 5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pribosyltran PF00156.27 AFI85802.1 - 1.5e-06 27.8 0.0 2.9e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AFI85802.1 - 0.00039 19.9 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AFI85802.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase GGDEF PF00990.21 AFI85803.1 - 1.1e-51 174.8 0.3 3.4e-51 173.2 0.1 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain DUF484 PF04340.12 AFI85803.1 - 2.7e-17 63.2 1.8 6.3e-17 62.0 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF484 GAF PF01590.26 AFI85803.1 - 1.8e-05 25.4 0.1 4.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 AFI85803.1 - 3.5e-05 24.1 0.1 7.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 GAF domain GGDEF_2 PF17853.1 AFI85803.1 - 4.4e-05 23.7 0.1 0.00014 22.1 0.0 1.8 2 0 0 2 2 2 1 GGDEF-like domain GAF_3 PF13492.6 AFI85803.1 - 0.0011 19.3 0.1 0.0031 17.9 0.1 1.8 1 1 0 1 1 1 1 GAF domain DUF1538 PF07556.11 AFI85804.1 - 1.5e-139 462.2 55.9 3.1e-70 235.8 22.5 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1538) BCL9 PF11502.8 AFI85805.1 - 0.0033 17.2 1.0 0.0045 16.7 0.1 1.7 2 0 0 2 2 2 1 B-cell lymphoma 9 protein HisG_C PF08029.11 AFI85805.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 HisG, C-terminal domain CBS PF00571.28 AFI85806.1 - 4.1e-21 75.2 3.2 2.7e-11 43.7 0.2 2.1 2 0 0 2 2 2 2 CBS domain Toprim_3 PF13362.6 AFI85806.1 - 0.0076 16.6 0.4 0.013 15.8 0.2 1.5 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 AFI85806.1 - 0.043 14.3 0.4 0.07 13.6 0.4 1.4 1 0 0 1 1 1 0 Toprim domain SNase PF00565.17 AFI85807.1 - 2.9e-21 76.0 0.0 4.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF4124 PF13511.6 AFI85807.1 - 1.5e-08 34.9 0.1 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4124) UbiA PF01040.18 AFI85808.1 - 9.7e-65 218.3 33.0 1.2e-64 218.1 33.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Chor_lyase PF04345.13 AFI85809.1 - 1.7e-31 109.1 0.1 2.1e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Chorismate lyase DUF98 PF01947.16 AFI85809.1 - 0.00024 21.1 0.0 0.00044 20.2 0.0 1.3 1 1 0 1 1 1 1 p-hydroxybenzoic acid synthase RecG_wedge PF17191.4 AFI85810.1 - 5.1e-22 78.2 0.0 8.7e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 RecG wedge domain Helicase_C PF00271.31 AFI85810.1 - 1.5e-21 76.8 0.1 1.9e-18 66.8 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 AFI85810.1 - 2.2e-20 73.1 1.7 4.7e-19 68.8 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AFI85810.1 - 1.8e-11 44.4 0.0 6e-11 42.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 AFI85810.1 - 4.8e-06 26.5 0.0 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain SecA_DEAD PF07517.14 AFI85810.1 - 2.7e-05 23.6 0.7 5.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain RC-P840_PscD PF10657.9 AFI85810.1 - 0.00027 21.0 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Photosystem P840 reaction centre protein PscD IMS_HHH PF11798.8 AFI85810.1 - 0.00034 20.8 0.4 0.0017 18.5 0.1 2.4 2 0 0 2 2 2 1 IMS family HHH motif SNF2_N PF00176.23 AFI85810.1 - 0.00091 18.0 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.6 AFI85810.1 - 0.0025 17.6 2.4 0.0026 17.5 0.4 2.1 2 1 0 2 2 2 1 AAA domain Cdd1 PF11731.8 AFI85810.1 - 0.0034 17.6 0.0 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 Pathogenicity locus AAA_22 PF13401.6 AFI85810.1 - 0.0097 16.2 3.6 10 6.4 0.2 4.2 1 1 2 3 3 3 1 AAA domain Glyco_tran_WecB PF03808.13 AFI85810.1 - 0.024 14.6 0.1 0.087 12.8 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF2075 PF09848.9 AFI85810.1 - 0.028 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 AFI85810.1 - 0.033 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase BAF PF02961.14 AFI85810.1 - 0.047 14.1 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Barrier to autointegration factor Helicase_RecD PF05127.14 AFI85810.1 - 0.27 11.1 1.2 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Helicase Ribonuc_L-PSP PF01042.21 AFI85811.1 - 1.3e-40 138.2 0.1 1.5e-40 138.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SepF PF04472.12 AFI85811.1 - 0.07 13.4 0.1 0.16 12.3 0.1 1.7 1 1 0 1 1 1 0 Cell division protein SepF HD_4 PF13328.6 AFI85812.1 - 1.3e-49 167.9 2.8 2.4e-49 167.1 2.8 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AFI85812.1 - 2.2e-36 124.7 0.0 2.1e-35 121.5 0.0 2.3 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TGS PF02824.21 AFI85812.1 - 5.1e-18 64.9 0.0 1.1e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AFI85812.1 - 1.3e-17 64.2 2.7 1.3e-17 64.2 2.7 2.0 2 0 0 2 2 2 1 ACT domain HD PF01966.22 AFI85812.1 - 1.6e-13 50.9 2.7 8.7e-13 48.6 2.6 2.2 2 0 0 2 2 2 1 HD domain ACT PF01842.25 AFI85812.1 - 2.7e-07 30.2 0.3 5.8e-07 29.2 0.3 1.6 1 0 0 1 1 1 1 ACT domain DUF493 PF04359.14 AFI85812.1 - 0.00075 20.0 0.0 0.0025 18.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF493) RNA_pol_Rpb6 PF01192.22 AFI85813.1 - 6.8e-18 64.3 0.0 1.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Guanylate_kin PF00625.21 AFI85814.1 - 3.6e-54 183.2 0.0 4.1e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AFI85814.1 - 9.8e-07 29.0 0.0 3.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AFI85814.1 - 0.0024 18.1 0.1 0.011 16.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AFI85814.1 - 0.0027 18.2 0.0 0.0057 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AFI85814.1 - 0.013 15.4 0.0 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B CPT PF07931.12 AFI85814.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 AFI85814.1 - 0.03 14.7 1.0 0.079 13.3 1.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AFI85814.1 - 0.032 14.0 0.5 0.058 13.1 0.1 1.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AFI85814.1 - 0.035 14.2 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AFI85814.1 - 0.048 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 AFI85814.1 - 0.058 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 AFI85814.1 - 0.098 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AFI85814.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter F420H2_quin_red PF04075.14 AFI85814.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase AAA_25 PF13481.6 AFI85814.1 - 0.16 11.5 2.3 2.6 7.6 0.2 2.9 3 0 0 3 3 3 0 AAA domain SBP_bac_6 PF13343.6 AFI85815.1 - 5.9e-22 78.3 0.0 7.8e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 AFI85815.1 - 4.2e-21 76.0 0.0 5.6e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AFI85815.1 - 4.6e-19 69.1 0.2 8.2e-19 68.3 0.2 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AFI85815.1 - 2e-17 64.1 0.0 3.6e-17 63.3 0.0 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4969 PF16339.5 AFI85815.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) BPD_transp_1 PF00528.22 AFI85816.1 - 2.6e-18 66.4 43.7 2.9e-13 50.0 13.7 3.2 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component DUF948 PF06103.11 AFI85816.1 - 1.9 8.8 0.0 1.9 8.8 0.0 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.27 AFI85817.1 - 3.2e-34 118.4 0.0 5e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 AFI85817.1 - 4.9e-11 42.6 0.3 6.1e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 TOBE domain AAA_21 PF13304.6 AFI85817.1 - 5.7e-11 42.8 0.2 7e-06 26.1 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFI85817.1 - 2.5e-05 23.8 0.1 0.059 12.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 AFI85817.1 - 0.00013 22.3 0.1 0.0023 18.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AFI85817.1 - 0.00018 22.0 0.2 0.00051 20.5 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 AFI85817.1 - 0.0016 18.6 0.5 0.011 16.0 0.5 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AFI85817.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AFI85817.1 - 0.0059 16.9 0.8 0.067 13.5 0.8 2.2 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AFI85817.1 - 0.011 16.2 0.1 0.033 14.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AFI85817.1 - 0.04 13.9 0.2 0.25 11.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AFI85817.1 - 0.048 13.4 0.1 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AFI85817.1 - 0.075 12.7 0.0 0.95 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 AFI85817.1 - 0.14 11.8 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AFI85817.1 - 0.19 11.5 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 AFI85817.1 - 0.21 11.5 0.1 0.45 10.4 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 AFI85820.1 - 7.3e-21 74.9 0.0 1.5e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AFI85820.1 - 3.9e-09 36.5 0.0 2.2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 AFI85820.1 - 9.2e-08 31.2 0.0 1.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AFI85820.1 - 5.4e-05 23.5 0.0 0.00018 21.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_primase_S PF01896.19 AFI85820.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 DNA primase small subunit PhoH PF02562.16 AFI85820.1 - 0.15 11.4 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SEC-C PF02810.15 AFI85824.1 - 5.2e-09 35.8 9.8 8.4e-09 35.2 9.8 1.3 1 0 0 1 1 1 1 SEC-C motif DUF2664 PF10867.8 AFI85825.1 - 0.00023 21.6 1.0 0.00053 20.4 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2664) AAA_14 PF13173.6 AFI85826.1 - 3.2e-23 82.2 0.0 8.8e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF4143 PF13635.6 AFI85826.1 - 3.7e-20 72.3 0.0 6.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4143) NTPase_1 PF03266.15 AFI85826.1 - 0.13 12.2 0.1 0.6 10.0 0.0 2.1 3 0 0 3 3 3 0 NTPase NERD PF08378.11 AFI85826.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Nuclease-related domain HTH_26 PF13443.6 AFI85827.1 - 0.00022 21.6 0.0 0.00028 21.3 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 AFI85827.1 - 0.00087 19.6 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AFI85827.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix HTH_25 PF13413.6 AFI85827.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_Tnp_1_2 PF13586.6 AFI85828.1 - 3.7e-18 65.7 0.6 4.1e-18 65.5 0.6 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85828.1 - 3.9e-10 39.8 3.6 2.8e-08 33.7 3.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI85828.1 - 6e-07 29.3 0.1 7.3e-07 29.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AFI85828.1 - 2.8e-06 27.4 0.0 3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Cellulase PF00150.18 AFI85828.1 - 0.077 12.4 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4096 PF13340.6 AFI85829.1 - 1.4e-25 89.3 3.8 2.6e-25 88.4 3.8 1.4 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) YicC_N PF03755.13 AFI85830.1 - 2.7e-37 128.6 0.4 2.7e-37 128.6 0.4 2.0 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 AFI85830.1 - 2.6e-36 123.5 2.6 6.7e-36 122.1 2.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) DUF4141 PF13605.6 AFI85830.1 - 0.046 13.0 0.4 0.097 11.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) RNase_PH PF01138.21 AFI85831.1 - 1.5e-25 90.2 0.0 3e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AFI85831.1 - 7.7e-10 38.7 0.1 1.2e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 B1 PF02246.15 AFI85831.1 - 0.055 13.5 0.1 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein L b1 domain Ham1p_like PF01725.16 AFI85832.1 - 3.1e-60 203.3 0.0 3.5e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF3755 PF12579.8 AFI85832.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Radical_SAM PF04055.21 AFI85833.1 - 1.3e-15 58.2 0.0 2.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AFI85833.1 - 4.9e-06 26.5 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 HemN C-terminal domain MarR_2 PF12802.7 AFI85833.1 - 0.025 14.4 0.6 0.74 9.7 0.0 3.2 4 0 0 4 4 4 0 MarR family Fer4_12 PF13353.6 AFI85833.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain SmpA_OmlA PF04355.13 AFI85834.1 - 0.13 12.1 1.2 0.28 11.0 1.2 1.7 1 1 0 1 1 1 0 SmpA / OmlA family Claudin_2 PF13903.6 AFI85835.1 - 0.0093 15.7 1.7 0.012 15.4 1.7 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF1772 PF08592.11 AFI85835.1 - 8.4 6.7 8.8 42 4.4 8.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3267 PF11667.8 AFI85835.1 - 8.6 6.7 12.9 1.6 9.1 5.3 2.3 1 1 1 2 2 2 0 Putative zincin peptidase PALP PF00291.25 AFI85836.1 - 1.3e-68 231.6 1.7 3e-68 230.4 1.7 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATPgrasp_N PF18130.1 AFI85836.1 - 0.11 13.1 0.1 0.52 10.9 0.1 2.1 1 1 1 2 2 2 0 ATP-grasp N-terminal domain Homoserine_dh PF00742.19 AFI85837.1 - 3.1e-65 219.3 0.5 5.2e-65 218.6 0.1 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 AFI85837.1 - 2.6e-21 76.4 0.2 6e-21 75.3 0.2 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 AFI85837.1 - 4.3e-12 45.6 0.0 9.4e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AFI85837.1 - 1.9e-05 25.2 0.1 7.4e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 ACT domain Sacchrp_dh_NADP PF03435.18 AFI85837.1 - 0.00053 20.2 0.2 0.0011 19.2 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 AFI85837.1 - 0.034 15.0 0.1 0.074 13.9 0.1 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ACT_6 PF13740.6 AFI85837.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 ACT domain Aminotran_1_2 PF00155.21 AFI85838.1 - 3.7e-60 204.0 0.0 4.5e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AFI85838.1 - 0.0021 16.6 0.0 0.0029 16.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HDOD PF08668.12 AFI85840.1 - 1.3e-50 171.7 0.9 1.8e-50 171.2 0.9 1.2 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AFI85840.1 - 0.041 14.1 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 HD domain DNA_binding_1 PF01035.20 AFI85841.1 - 1.2e-25 89.4 0.0 1.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RsmJ PF04378.13 AFI85842.1 - 7.6e-76 254.6 0.0 8.7e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 AFI85842.1 - 6e-05 22.8 0.0 0.00083 19.0 0.0 2.3 3 0 0 3 3 3 1 Conserved hypothetical protein 95 Oxidored_FMN PF00724.20 AFI85843.1 - 7.7e-64 216.1 0.0 1e-63 215.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AFI85843.1 - 0.00024 20.3 0.0 0.00097 18.3 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Trp_syntA PF00290.20 AFI85843.1 - 0.08 11.8 0.0 2.6 6.8 0.0 2.4 1 1 1 2 2 2 0 Tryptophan synthase alpha chain adh_short_C2 PF13561.6 AFI85844.1 - 1.5e-46 158.9 0.3 5.5e-46 157.0 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AFI85844.1 - 2.4e-45 154.4 0.1 3e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AFI85844.1 - 1.9e-10 41.0 0.0 3.2e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AFI85844.1 - 0.00091 18.8 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AFI85844.1 - 0.0037 17.2 0.1 0.0052 16.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 AFI85844.1 - 0.036 13.9 0.3 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AhpC-TSA PF00578.21 AFI85845.1 - 1.5e-18 66.9 0.1 2.3e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AFI85845.1 - 7.3e-16 58.2 0.0 1.2e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 AFI85845.1 - 8.2e-11 41.8 0.1 1.9e-08 34.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 AFI85845.1 - 4.9e-09 36.4 0.0 7.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like LGT PF01790.18 AFI85845.1 - 4.5e-06 26.1 1.1 6.1e-06 25.6 1.1 1.3 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Thioredoxin_2 PF13098.6 AFI85845.1 - 8.9e-06 26.1 0.0 1.3e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 AFI85845.1 - 0.00011 22.0 0.1 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF998 PF06197.13 AFI85845.1 - 0.12 12.0 6.0 0.25 10.9 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF4131 PF13567.6 AFI85845.1 - 4.8 6.8 6.9 0.99 9.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Thioredoxin_2 PF13098.6 AFI85846.1 - 6.7e-16 58.7 0.0 1.5e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 AFI85846.1 - 2.8e-06 27.6 0.3 5.2e-05 23.5 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 AFI85846.1 - 0.0043 17.1 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.24 AFI85846.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Mob_synth_C PF06463.13 AFI85846.1 - 0.027 14.4 0.2 0.26 11.2 0.1 2.5 2 1 0 2 2 2 0 Molybdenum Cofactor Synthesis C DsbC_N PF10411.9 AFI85846.1 - 0.029 13.8 0.0 0.083 12.4 0.0 1.8 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Thioredoxin PF00085.20 AFI85846.1 - 0.05 13.6 0.1 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Ibs_toxin PF13956.6 AFI85846.1 - 0.073 13.1 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Thioredoxin_7 PF13899.6 AFI85846.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like MFS_4 PF06779.14 AFI85847.1 - 3.2e-76 257.0 38.4 3.7e-76 256.8 38.4 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 AFI85847.1 - 6.6e-23 81.2 79.5 3.4e-16 59.1 47.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 AFI85847.1 - 0.047 14.4 0.5 0.11 13.1 0.5 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5310 PF17237.2 AFI85847.1 - 0.23 11.4 1.2 0.84 9.6 1.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5310) MFS_1_like PF12832.7 AFI85847.1 - 0.64 8.8 24.6 1.9 7.3 18.0 2.5 1 1 1 2 2 2 0 MFS_1 like family DUF5640 PF18692.1 AFI85848.1 - 0.0012 18.9 0.3 0.0016 18.4 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5640) DUF2157 PF09925.9 AFI85849.1 - 0.087 12.6 0.1 0.087 12.6 0.1 3.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Wzy_C PF04932.15 AFI85849.1 - 0.21 11.2 11.0 50 3.5 11.0 2.7 1 1 0 1 1 1 0 O-Antigen ligase IncE PF17627.2 AFI85849.1 - 0.55 10.3 3.8 0.3 11.1 0.2 2.2 2 1 1 3 3 3 0 Inclusion membrane protein E Pox_P21 PF05313.12 AFI85849.1 - 6.9 6.2 13.2 1.2 8.6 2.4 2.4 2 1 0 2 2 2 0 Poxvirus P21 membrane protein Ion_trans_2 PF07885.16 AFI85851.1 - 7.8e-05 22.6 13.3 0.0002 21.3 8.7 2.8 2 1 0 2 2 2 1 Ion channel DUF1129 PF06570.11 AFI85851.1 - 0.038 13.5 0.8 0.052 13.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Abhydrolase_9_N PF15420.6 AFI85851.1 - 0.075 13.0 2.8 0.1 12.6 2.4 1.4 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PhoR PF11808.8 AFI85851.1 - 0.6 10.6 6.6 0.78 10.2 0.1 2.2 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR HI0933_like PF03486.14 AFI85852.1 - 3.5e-144 480.5 0.0 3.9e-144 480.3 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AFI85852.1 - 6.9e-12 45.2 8.0 1.9e-09 37.1 2.7 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AFI85852.1 - 1.1e-10 41.3 0.7 2.3e-09 36.9 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AFI85852.1 - 5.3e-10 39.2 0.0 8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AFI85852.1 - 7.7e-10 38.5 2.5 0.00085 18.7 1.5 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AFI85852.1 - 1.1e-08 35.0 7.4 0.0009 18.9 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 AFI85852.1 - 5.7e-07 29.0 6.8 0.0019 17.4 2.2 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AFI85852.1 - 1.1e-05 25.6 1.9 3e-05 24.2 1.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AFI85852.1 - 1.1e-05 25.8 2.5 0.084 13.5 0.5 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AFI85852.1 - 5.7e-05 22.3 1.6 0.0004 19.5 1.6 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 AFI85852.1 - 0.0002 20.7 0.6 0.0048 16.2 0.1 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 AFI85852.1 - 0.00028 20.9 0.1 0.00086 19.3 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AFI85852.1 - 0.0028 16.9 0.4 0.0071 15.6 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 AFI85852.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain APH PF01636.23 AFI85853.1 - 0.00042 20.3 0.1 0.00074 19.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 AFI85853.1 - 0.042 13.4 0.0 0.086 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL YAcAr PF10686.9 AFI85853.1 - 0.35 10.9 1.9 0.73 9.8 1.9 1.5 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family PEMT PF04191.13 AFI85854.1 - 7.3e-07 29.5 0.2 7.3e-07 29.5 0.2 2.0 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 AFI85854.1 - 1.2e-06 28.8 0.1 3.1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 AFI85854.1 - 0.022 14.3 1.4 0.032 13.8 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DUF4131 PF13567.6 AFI85854.1 - 0.86 9.2 8.6 0.44 10.2 1.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) NLPC_P60 PF00877.19 AFI85856.1 - 3.1e-30 104.3 0.0 3.6e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 NlpC/P60 family Trypsin_2 PF13365.6 AFI85857.1 - 1.2e-05 26.2 0.0 3.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AFI85857.1 - 6.1e-05 22.9 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 2 Trypsin Erythro_esteras PF05139.14 AFI85858.1 - 1e-121 407.0 1.3 1.4e-121 406.6 1.3 1.2 1 0 0 1 1 1 1 Erythromycin esterase PCMT PF01135.19 AFI85858.1 - 6.6e-61 205.7 0.0 1e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AFI85858.1 - 8.9e-07 28.2 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 AFI85858.1 - 2.4e-05 24.2 0.0 6.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AFI85858.1 - 0.012 16.2 0.0 0.07 13.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Cofac_haem_bdg PF04187.13 AFI85858.1 - 0.017 15.1 0.1 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Methyltransf_23 PF13489.6 AFI85858.1 - 0.026 14.4 0.0 0.071 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 AFI85858.1 - 0.039 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 AFI85858.1 - 0.047 14.3 0.0 0.17 12.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 AFI85858.1 - 0.064 13.3 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 AFI85858.1 - 0.075 12.5 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltr_RsmB-F PF01189.17 AFI85858.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF3617 PF12276.8 AFI85859.1 - 2e-10 41.1 3.2 2.2e-10 41.0 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) MAPEG PF01124.18 AFI85860.1 - 6.5e-19 68.1 6.9 7.8e-19 67.9 6.9 1.0 1 0 0 1 1 1 1 MAPEG family Orf78 PF06024.12 AFI85860.1 - 0.46 10.8 2.2 9.6 6.6 0.2 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Hexapep PF00132.24 AFI85861.1 - 4.6e-19 67.4 1.5 1.3e-06 27.9 0.3 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AFI85861.1 - 5.9e-06 25.9 9.1 0.00029 20.5 1.2 3.8 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase HDOD PF08668.12 AFI85862.1 - 6.4e-37 126.9 3.4 9.2e-37 126.4 3.4 1.2 1 0 0 1 1 1 1 HDOD domain LAP2alpha PF11560.8 AFI85862.1 - 0.00023 20.7 1.1 0.0059 16.1 0.2 2.2 2 0 0 2 2 2 2 Lamina-associated polypeptide 2 alpha DUF3391 PF11871.8 AFI85863.1 - 1.7e-29 103.1 0.0 2.7e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HD_5 PF13487.6 AFI85863.1 - 6.2e-17 61.6 0.1 1.6e-16 60.3 0.1 1.7 2 0 0 2 2 2 1 HD domain HD PF01966.22 AFI85863.1 - 6.5e-17 61.9 0.1 1e-16 61.3 0.1 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AFI85863.1 - 5.8e-05 22.7 0.5 0.00019 21.0 0.5 1.8 1 1 0 1 1 1 1 HDOD domain DDE_Tnp_1_2 PF13586.6 AFI85864.1 - 1.8e-16 60.3 0.8 2e-16 60.1 0.8 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85864.1 - 2.4e-09 37.1 3.7 2.6e-07 30.5 3.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI85864.1 - 3.5e-06 26.8 0.1 4.4e-06 26.4 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AFI85864.1 - 5.5e-06 26.5 0.0 5.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 AFI85864.1 - 0.0041 16.5 0.1 0.0041 16.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Cellulase PF00150.18 AFI85864.1 - 0.045 13.2 0.0 0.054 12.9 0.0 1.0 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4096 PF13340.6 AFI85865.1 - 1.4e-25 89.3 3.8 2.6e-25 88.4 3.8 1.4 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) ABC2_membrane PF01061.24 AFI85866.1 - 9e-34 116.7 25.5 9e-34 116.7 25.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AFI85866.1 - 7.8e-06 25.2 36.5 7.8e-06 25.2 36.5 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 AFI85867.1 - 1e-32 113.5 0.0 2.6e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AFI85867.1 - 4.7e-14 52.9 0.1 4.8e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AFI85867.1 - 2.2e-05 25.1 0.9 7.2e-05 23.4 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 AFI85867.1 - 6.9e-05 23.4 1.9 0.00016 22.3 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AFI85867.1 - 0.00012 22.0 0.1 0.095 12.4 0.0 2.6 2 1 0 3 3 3 2 AAA ATPase domain TsaE PF02367.17 AFI85867.1 - 0.00033 20.6 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 AFI85867.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AFI85867.1 - 0.0012 18.3 0.1 0.32 10.4 0.0 2.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 AFI85867.1 - 0.0032 17.9 0.1 0.048 14.1 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 AFI85867.1 - 0.0052 16.5 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AFI85867.1 - 0.0084 16.0 0.2 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 AFI85867.1 - 0.0087 15.8 0.2 0.84 9.3 0.0 2.5 3 0 0 3 3 3 1 IstB-like ATP binding protein ATPase PF06745.13 AFI85867.1 - 0.011 15.1 0.8 0.83 8.9 0.3 2.4 2 1 0 2 2 2 0 KaiC NTPase_1 PF03266.15 AFI85867.1 - 0.014 15.3 0.8 0.16 11.9 0.0 2.6 3 0 0 3 3 3 0 NTPase SRP54 PF00448.22 AFI85867.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Hydrolase PF00702.26 AFI85867.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.6 2 0 0 2 2 1 0 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 AFI85867.1 - 0.018 15.5 0.1 0.063 13.6 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AFI85867.1 - 0.068 12.9 0.1 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AFI85867.1 - 0.074 13.3 1.0 3.9 7.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain Gp-FAR-1 PF05823.12 AFI85867.1 - 0.084 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) OSK PF17182.4 AFI85867.1 - 0.087 12.1 0.1 0.19 10.9 0.0 1.5 1 1 0 1 1 1 0 OSK domain cobW PF02492.19 AFI85867.1 - 0.1 12.2 0.1 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 AFI85867.1 - 0.14 11.8 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain LPAM_1 PF08139.12 AFI85869.1 - 0.081 13.4 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DDE_Tnp_1_3 PF13612.6 AFI85870.1 - 1.9e-77 258.6 0.0 2.7e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85870.1 - 7.9e-23 81.2 0.1 1.1e-21 77.5 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AFI85870.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Transposase DDE domain DUF3144 PF11342.8 AFI85871.1 - 3.4e-31 107.4 3.0 4.7e-31 106.9 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3144) DUF4125 PF13526.6 AFI85871.1 - 0.031 13.9 0.6 0.036 13.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) AA_permease_2 PF13520.6 AFI85873.1 - 3.8e-35 121.5 44.0 4.7e-35 121.2 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AFI85873.1 - 3.1e-27 95.3 42.8 3.9e-27 95.0 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease DeoRC PF00455.22 AFI85874.1 - 1.2e-41 142.3 0.3 1.8e-41 141.8 0.3 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 AFI85874.1 - 2.5e-15 55.9 0.4 5.7e-15 54.8 0.4 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_Crp_2 PF13545.6 AFI85874.1 - 0.00024 21.0 0.2 0.00062 19.7 0.2 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AFI85874.1 - 0.00029 20.7 0.7 0.00061 19.7 0.7 1.6 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 AFI85874.1 - 0.00038 20.0 0.1 0.00088 18.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 AFI85874.1 - 0.0086 16.0 0.8 0.015 15.2 0.2 1.7 2 0 0 2 2 2 1 MarR family TF_AP-2 PF03299.14 AFI85874.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor AP-2 MarR_2 PF12802.7 AFI85874.1 - 0.025 14.5 0.3 0.054 13.4 0.3 1.6 1 0 0 1 1 1 0 MarR family HxlR PF01638.17 AFI85874.1 - 0.025 14.4 0.1 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Shikimate_DH PF01488.20 AFI85874.1 - 0.033 14.2 0.1 0.096 12.7 0.1 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HTH_AsnC-type PF13404.6 AFI85874.1 - 0.055 13.3 0.5 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 AFI85874.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 AFI85874.1 - 0.074 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus APH PF01636.23 AFI85875.1 - 7.7e-31 107.8 0.3 1.4e-30 107.0 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 AFI85875.1 - 1.9e-05 24.3 0.2 6.2e-05 22.7 0.0 1.9 3 0 0 3 3 3 1 Choline/ethanolamine kinase RIO1 PF01163.22 AFI85875.1 - 0.00071 19.2 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 AFI85875.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain UAE_UbL PF14732.6 AFI85875.1 - 0.039 14.5 0.1 4.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DDE_Tnp_1_3 PF13612.6 AFI85876.1 - 7.6e-80 266.4 0.1 1.1e-79 265.9 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85876.1 - 3.6e-22 79.1 0.8 1.1e-20 74.2 0.8 2.1 1 1 0 1 1 1 1 Transposase DDE domain rve PF00665.26 AFI85877.1 - 6e-21 74.8 0.0 8.1e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AFI85877.1 - 6.1e-12 45.5 0.3 9.6e-12 44.9 0.3 1.3 1 0 0 1 1 1 1 HTH-like domain rve_3 PF13683.6 AFI85877.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_1 PF01527.20 AFI85878.1 - 5.7e-19 68.2 1.1 8.6e-19 67.6 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 AFI85878.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain NBP1 PF08537.10 AFI85878.1 - 0.0069 15.8 0.2 0.0069 15.8 0.2 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 HTH_29 PF13551.6 AFI85878.1 - 0.017 15.1 0.0 0.042 13.9 0.0 1.7 1 1 1 2 2 2 0 Winged helix-turn helix Prp18 PF02840.15 AFI85878.1 - 0.025 14.6 0.4 0.037 14.1 0.4 1.2 1 0 0 1 1 1 0 Prp18 domain Ly49 PF08391.10 AFI85878.1 - 0.16 12.3 0.3 0.24 11.7 0.3 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Peptidase_U32 PF01136.19 AFI85879.1 - 1.2e-98 328.9 0.0 3.4e-98 327.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family U32 Peptidase_U32_C PF16325.5 AFI85879.1 - 1.1e-17 64.1 0.0 3.2e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family U32 C-terminal domain Tachystatin_B PF11478.8 AFI85879.1 - 0.06 13.3 1.0 0.13 12.2 1.0 1.6 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B DDE_Tnp_1_2 PF13586.6 AFI85880.1 - 5.9e-18 65.0 0.7 6.7e-18 64.9 0.7 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AFI85880.1 - 4.6e-10 39.5 3.7 4.7e-08 32.9 3.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AFI85880.1 - 1.3e-06 28.2 0.1 1.6e-06 27.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 AFI85880.1 - 2.2e-06 27.7 0.0 2.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Cellulase PF00150.18 AFI85880.1 - 0.047 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DUF4096 PF13340.6 AFI85881.1 - 3.8e-25 87.9 3.8 7e-25 87.0 3.8 1.4 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) nos_propeller PF18764.1 AJO16109.1 - 2.8e-37 126.4 0.8 1.2e-34 118.0 0.2 2.9 3 0 0 3 3 3 2 Nitrous oxide reductase propeller repeat nos_propeller_2 PF18793.1 AJO16109.1 - 4.8e-35 119.7 1.0 9.7e-34 115.5 0.2 2.8 2 0 0 2 2 2 1 Nitrous oxide reductase propeller repeat 2 COX2 PF00116.20 AJO16109.1 - 2e-05 24.5 0.5 5.2e-05 23.1 0.5 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AJO16109.1 - 3.1e-05 24.0 0.0 6.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain Cu-oxidase_3 PF07732.15 AJO16109.1 - 0.0023 17.9 0.7 0.0057 16.7 0.3 2.0 2 0 0 2 2 2 1 Multicopper oxidase UCR_Fe-S_N PF10399.9 AJO16109.1 - 0.014 14.7 0.3 0.026 13.9 0.3 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 AJO16109.1 - 0.025 14.4 4.9 0.039 13.8 4.9 1.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylophaga_nitratireducenticrescens-ASM26098v2/GCA_000260985.2_ASM26098v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylophaga_nitratireducenticrescens-ASM26098v2/GCA_000260985.2_ASM26098v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylophaga_nitratireducenticrescens-ASM26098v2/GCA_000260985.2_ASM26098v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylophaga_nitratireducenticrescens-ASM26098v2/GCA_000260985.2_ASM26098v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:12:33 2019 # [ok]