# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- EAL PF00563.20 AMK74882.1 - 6.2e-65 219.0 0.1 4.6e-64 216.2 0.0 2.2 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK74882.1 - 1.6e-52 177.5 1.3 3.2e-52 176.5 1.3 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK74882.1 - 5.6e-24 84.5 0.0 1.2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 AMK74882.1 - 7.9e-22 77.5 0.0 3.8e-12 46.4 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK74882.1 - 1.4e-19 70.1 0.2 2e-08 34.2 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AMK74882.1 - 3.4e-17 62.7 0.0 3.1e-10 40.3 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AMK74882.1 - 3.8e-11 42.7 0.1 2.7e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 AMK74882.1 - 5.5e-11 42.6 0.0 1.5e-08 34.8 0.0 2.8 3 0 0 3 3 3 1 PAS fold HisKA_2 PF07568.12 AMK74883.1 - 9.8e-27 92.9 5.5 2.1e-26 91.8 0.2 2.9 3 0 0 3 3 3 1 Histidine kinase PAS PF00989.25 AMK74883.1 - 3.3e-23 81.8 0.0 8e-10 38.7 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 AMK74883.1 - 6.8e-23 80.9 0.0 7.4e-10 39.0 0.0 4.0 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.7 AMK74883.1 - 1.9e-18 66.0 0.1 7.5e-08 32.2 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AMK74883.1 - 2.6e-11 43.8 0.1 0.0003 21.0 0.0 2.9 2 1 0 2 2 2 2 PAS fold GAF PF01590.26 AMK74883.1 - 2.6e-08 34.6 0.0 1.1e-07 32.5 0.0 2.1 2 0 0 2 2 2 1 GAF domain HATPase_c PF02518.26 AMK74883.1 - 1.5e-06 28.7 0.0 4.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 AMK74883.1 - 1.7e-05 25.5 0.9 4.8e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 HWE histidine kinase GAF_3 PF13492.6 AMK74883.1 - 0.0001 22.7 0.0 0.00036 20.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AMK74883.1 - 0.00017 21.9 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 AMK74883.1 - 0.00094 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Polysacc_deac_2 PF04748.13 AMK74883.1 - 0.011 14.9 0.6 2.9 7.0 0.1 2.7 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase PAS_7 PF12860.7 AMK74883.1 - 0.062 13.5 0.3 24 5.1 0.0 3.2 3 1 0 3 3 3 0 PAS fold DUF3107 PF11305.8 AMK74883.1 - 3.4 8.0 6.9 13 6.1 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3107) EAL PF00563.20 AMK74885.1 - 1.1e-73 247.7 0.0 1.8e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK74885.1 - 4.5e-50 169.5 1.9 2e-49 167.4 0.1 2.3 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK74885.1 - 6.9e-20 71.3 0.2 2.4e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 PAS domain Response_reg PF00072.24 AMK74885.1 - 7.8e-19 67.9 0.0 2.5e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AMK74885.1 - 2.3e-12 46.9 0.0 8.1e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AMK74885.1 - 3e-09 37.1 0.0 7.3e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK74885.1 - 1.8e-06 28.1 0.0 8.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AMK74885.1 - 3.7e-05 23.6 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain Rootletin PF15035.6 AMK74885.1 - 0.025 14.6 3.8 0.047 13.7 3.8 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2802 PF10975.8 AMK74885.1 - 0.081 13.1 2.1 0.26 11.4 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) MRPL52 PF18699.1 AMK74885.1 - 2.6 8.3 5.7 5.5 7.2 5.7 1.4 1 0 0 1 1 1 0 Mitoribosomal protein mL52 HATPase_c PF02518.26 AMK74886.1 - 5.8e-23 81.5 0.1 1.5e-22 80.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AMK74886.1 - 3.5e-14 52.9 0.0 3.3e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AMK74886.1 - 3.1e-11 43.1 5.7 1.6e-09 37.6 0.0 3.8 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 AMK74886.1 - 3.3e-08 33.9 0.0 7.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AMK74886.1 - 5.7e-07 30.2 0.0 3.1e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AMK74886.1 - 1.5e-06 28.6 0.0 3.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.7 AMK74886.1 - 6.4e-05 23.2 0.1 0.00037 20.7 0.0 2.4 2 0 0 2 2 1 1 PAS domain PAS_4 PF08448.10 AMK74886.1 - 0.0001 22.5 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AMK74886.1 - 0.00038 20.3 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 GHKL domain Mce4_CUP1 PF11887.8 AMK74886.1 - 0.0027 17.2 0.8 0.081 12.4 0.1 2.2 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative Talin_middle PF09141.10 AMK74886.1 - 0.03 14.4 2.4 0.78 9.8 0.1 2.9 2 1 1 3 3 3 0 Talin, middle domain HATPase_c_2 PF13581.6 AMK74886.1 - 0.033 14.1 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Jnk-SapK_ap_N PF09744.9 AMK74886.1 - 0.045 14.0 2.3 3.4 7.9 0.5 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 APG17 PF04108.12 AMK74886.1 - 0.054 12.6 5.6 0.13 11.4 5.6 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 HATPase_c_3 PF13589.6 AMK74886.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MscS_porin PF12795.7 AMK74886.1 - 0.42 10.1 12.8 0.25 10.8 1.3 2.6 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 AMK74886.1 - 1.9 8.5 9.8 1 9.3 0.7 2.7 3 0 0 3 3 3 0 Laminin Domain II UPF0449 PF15136.6 AMK74886.1 - 5.6 7.5 6.2 2.7 8.5 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HDOD PF08668.12 AMK74887.1 - 6.1e-56 189.0 0.0 8.6e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK74887.1 - 3.1e-10 40.3 0.5 5.9e-10 39.4 0.5 1.5 1 1 0 1 1 1 1 HD domain tRNA-synt_2_TM PF16995.5 AMK74887.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Response_reg PF00072.24 AMK74888.1 - 6.7e-22 77.8 0.0 1.7e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AMK74888.1 - 0.00066 19.7 0.5 0.0076 16.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold PRKG1_interact PF15898.5 AMK74888.1 - 0.0037 18.2 1.4 0.0077 17.1 1.4 1.5 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain DUF3865 PF12981.7 AMK74888.1 - 0.004 17.1 0.2 0.025 14.5 0.0 2.0 1 1 0 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3865) GAS PF13851.6 AMK74888.1 - 0.023 14.1 5.1 0.036 13.4 5.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MobL PF18555.1 AMK74888.1 - 0.035 13.3 0.6 0.051 12.8 0.6 1.2 1 0 0 1 1 1 0 MobL relaxases PAS_10 PF13596.6 AMK74888.1 - 0.11 13.1 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 PAS domain DDE_Tnp_1 PF01609.21 AMK74889.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK74889.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK74889.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK74889.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK74889.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK74889.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK74889.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK74889.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK74889.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK74889.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK74889.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK74889.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK74889.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain Resolvase PF00239.21 AMK74890.1 - 0.0011 19.0 0.0 0.0014 18.7 0.0 1.3 1 1 0 1 1 1 1 Resolvase, N terminal domain HATPase_c PF02518.26 AMK74892.1 - 1.5e-31 109.2 0.5 3.4e-31 108.0 0.5 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AMK74892.1 - 2e-26 92.1 0.1 2.2e-23 82.3 0.1 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AMK74892.1 - 4.7e-25 87.8 0.0 2.8e-15 56.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.24 AMK74892.1 - 6.3e-22 77.9 0.1 4.8e-21 75.0 0.1 2.5 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.7 AMK74892.1 - 7.7e-20 71.1 0.0 2.3e-10 40.6 0.0 3.1 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 AMK74892.1 - 5.9e-18 64.7 0.6 2.7e-17 62.5 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK74892.1 - 1.1e-15 57.8 2.4 1.3e-15 57.4 0.2 2.5 2 0 0 2 2 2 1 HAMP domain PAS_4 PF08448.10 AMK74892.1 - 2e-12 47.3 0.0 0.00012 22.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold Hpt PF01627.23 AMK74892.1 - 1.9e-05 24.8 1.2 1.9e-05 24.8 1.2 3.9 3 0 0 3 3 3 1 Hpt domain PAS_8 PF13188.7 AMK74892.1 - 0.00011 22.1 0.0 0.00068 19.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.6 AMK74892.1 - 0.00019 21.3 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AMK74892.1 - 0.015 15.9 0.0 0.61 10.7 0.0 3.0 3 0 0 3 3 2 0 PAS domain MadM PF03818.13 AMK74892.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit PAS_11 PF14598.6 AMK74892.1 - 0.1 12.7 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 PAS domain Response_reg PF00072.24 AMK74893.1 - 8.7e-27 93.5 0.2 1.3e-26 92.9 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AMK74893.1 - 3e-22 79.1 0.4 1.6e-21 76.7 0.1 2.1 2 1 0 2 2 2 1 HD domain HD_5 PF13487.6 AMK74893.1 - 6.5e-18 64.8 0.0 2.2e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 HD domain B12-binding PF02310.19 AMK74893.1 - 0.00057 19.9 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain VPR PF00522.18 AMK74893.1 - 0.093 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 VPR/VPX protein DUF1378 PF07125.11 AMK74895.1 - 0.021 15.0 0.2 0.046 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Myf5 PF12232.8 AMK74896.1 - 0.45 11.3 4.1 0.19 12.5 1.3 1.7 2 0 0 2 2 2 0 Myogenic determination factor 5 DUF4410 PF14366.6 AMK74897.1 - 1.6e-09 37.7 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4410) HGTP_anticodon PF03129.20 AMK74897.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain DUF2624 PF11116.8 AMK74897.1 - 0.067 14.1 0.1 0.13 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) SEC-C PF02810.15 AMK74899.1 - 2.6e-08 33.6 5.8 3.6e-08 33.2 5.8 1.2 1 0 0 1 1 1 1 SEC-C motif MqsA_antitoxin PF15731.5 AMK74900.1 - 5.9e-09 36.1 0.1 6.5e-09 36.0 0.1 1.0 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA YokU PF14122.6 AMK74900.1 - 0.0017 18.3 0.1 0.0019 18.1 0.1 1.1 1 0 0 1 1 1 1 YokU-like protein, putative antitoxin TF_Zn_Ribbon PF08271.12 AMK74900.1 - 0.015 14.8 0.5 2 8.0 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 AMK74900.1 - 0.017 15.2 0.8 0.034 14.2 0.0 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 AMK74900.1 - 0.018 15.0 0.1 0.018 15.0 0.1 1.9 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.6 AMK74900.1 - 0.19 11.2 4.1 2.4 7.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 AMK74900.1 - 0.22 11.2 2.6 4.3 7.1 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rubredoxin_2 PF18073.1 AMK74900.1 - 0.5 10.1 2.9 4.7 7.0 0.4 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C2HC_2 PF13913.6 AMK74900.1 - 1.3 9.0 5.3 4.3 7.4 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF4258 PF14076.6 AMK74901.1 - 1.2e-15 57.6 0.0 1.4e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) AA_permease_N PF08403.10 AMK74902.1 - 0.022 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF2442 PF10387.9 AMK74903.1 - 1.4e-19 70.2 0.1 1.5e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2442) DUF4160 PF13711.6 AMK74904.1 - 9.7e-25 86.7 0.8 1.1e-24 86.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) Ribonuc_red_lgC PF02867.15 AMK74905.1 - 4.1e-140 467.8 0.0 5e-140 467.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AMK74905.1 - 1.3e-06 28.3 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain DUF533 PF04391.12 AMK74906.1 - 0.12 11.9 4.0 0.17 11.5 4.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF533) SNF2_N PF00176.23 AMK74907.1 - 2.1e-50 171.4 0.0 3.2e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AMK74907.1 - 1.6e-20 73.5 0.0 4.9e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_assoc PF08455.10 AMK74907.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated DEAD_2 PF06733.15 AMK74907.1 - 0.024 14.3 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 ECM11 PF15463.6 AMK74907.1 - 0.2 12.2 2.2 0.87 10.2 0.1 2.8 4 0 0 4 4 4 0 Extracellular mutant protein 11 CoA_binding PF02629.19 AMK74908.1 - 1.3e-26 93.0 0.7 1.3e-26 93.0 0.7 3.0 2 1 1 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 AMK74908.1 - 1.1e-13 51.3 0.5 2.1e-13 50.4 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AMK74908.1 - 2.9e-11 43.3 0.1 5.2e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AMK74908.1 - 0.0022 18.5 0.0 0.012 16.1 0.0 2.1 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 AMK74908.1 - 0.054 14.3 0.6 0.15 12.9 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 AMK74908.1 - 0.06 13.5 3.6 0.24 11.5 0.3 2.7 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PPV_E1_C PF00519.17 AMK74908.1 - 0.24 10.2 0.1 0.34 9.7 0.1 1.1 1 0 0 1 1 1 0 Papillomavirus helicase ATP-grasp_2 PF08442.10 AMK74909.1 - 2.6e-77 259.0 1.9 2.9e-77 258.8 0.3 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 AMK74909.1 - 2.7e-26 92.2 0.8 5.2e-26 91.3 0.8 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AMK74909.1 - 2.3e-11 43.6 4.4 1.9e-10 40.6 1.0 3.0 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 AMK74909.1 - 0.001 18.9 0.3 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HpcH_HpaI PF03328.14 AMK74910.1 - 5.8e-40 136.8 0.4 8.9e-40 136.2 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 AMK74910.1 - 8.8e-10 38.2 0.0 0.00041 19.6 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Malate_synthase PF01274.22 AMK74910.1 - 0.013 13.8 0.1 1.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Malate synthase Aminotran_5 PF00266.19 AMK74911.1 - 2.4e-33 115.6 0.0 3.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DnaJ PF00226.31 AMK74913.1 - 0.00031 20.8 2.3 0.00037 20.6 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain MutS_II PF05188.17 AMK74913.1 - 3.2 8.0 7.3 4.6 7.5 4.5 2.4 2 2 1 3 3 3 0 MutS domain II TFIIA PF03153.13 AMK74913.1 - 3.8 7.4 20.2 5.4 6.9 20.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2-Hacid_dh_C PF02826.19 AMK74914.1 - 5.5e-56 188.7 0.0 8.9e-56 188.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AMK74914.1 - 3.6e-27 94.7 0.0 4e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AMK74914.1 - 8.1e-07 29.3 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CCP_MauG PF03150.14 AMK74916.1 - 6.6e-21 75.5 0.0 2.4e-19 70.5 0.0 3.1 3 1 0 3 3 3 1 Di-haem cytochrome c peroxidase PEP-CTERM PF07589.11 AMK74917.1 - 0.021 14.9 0.7 0.021 14.9 0.7 2.6 2 0 0 2 2 2 0 PEP-CTERM motif Redoxin PF08534.10 AMK74918.1 - 2.8e-27 95.3 0.0 3.3e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AMK74918.1 - 4.6e-24 84.7 0.0 5.4e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AMK74918.1 - 6.9e-18 64.8 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AMK74918.1 - 5.6e-11 42.4 0.0 2.5e-09 37.0 0.0 2.1 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AMK74918.1 - 2.4e-05 24.8 0.0 3.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 AMK74918.1 - 0.00025 20.8 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin SCO1-SenC PF02630.14 AMK74918.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.5 1 1 1 2 2 2 1 SCO1/SenC AhpC-TSA_2 PF13911.6 AMK74918.1 - 0.05 13.7 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Thioredoxin_7 PF13899.6 AMK74918.1 - 0.073 13.3 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like GSHPx PF00255.19 AMK74918.1 - 0.073 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase DUF4266 PF14086.6 AMK74919.1 - 1.6e-21 77.0 0.1 2.1e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4266) DUF3570 PF12094.8 AMK74920.1 - 3.1e-97 326.0 18.9 3.7e-81 273.1 12.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3570) Sulfotransfer_3 PF13469.6 AMK74922.1 - 1.8e-27 97.2 0.4 4.8e-27 95.7 0.1 1.9 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 AMK74922.1 - 1.9e-12 47.2 0.0 4.4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain TPR_2 PF07719.17 AMK74922.1 - 2.8e-11 42.6 20.2 0.00084 19.3 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 AMK74922.1 - 6.8e-11 41.5 0.7 0.0033 17.5 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AMK74922.1 - 2.9e-10 39.5 6.5 0.025 14.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 AMK74922.1 - 3.7e-10 40.2 12.7 6.9e-05 23.3 1.2 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 AMK74922.1 - 5.7e-10 39.2 14.8 0.0013 19.4 0.0 5.8 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AMK74922.1 - 3.4e-08 33.7 17.1 0.0077 16.5 0.4 5.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 AMK74922.1 - 3.9e-07 30.0 2.3 0.36 11.3 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK74922.1 - 5.2e-07 29.8 3.2 0.0089 16.2 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AMK74922.1 - 2.5e-06 27.1 1.0 0.51 10.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 AMK74922.1 - 6e-06 26.3 6.9 0.024 14.8 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AMK74922.1 - 1.8e-05 24.3 1.5 0.017 14.8 0.0 3.9 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 AMK74922.1 - 0.00052 20.6 14.7 0.0093 16.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 AMK74922.1 - 0.0057 15.9 1.8 0.012 14.8 0.5 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 AMK74922.1 - 0.012 15.4 11.0 2.1 8.3 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 AMK74922.1 - 0.017 15.0 1.3 3.3 7.6 0.5 2.4 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_20 PF14561.6 AMK74922.1 - 0.019 15.3 6.9 0.86 10.0 2.6 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 AMK74922.1 - 7.4 7.4 7.8 1.7e+02 3.2 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Cytochrom_C PF00034.21 AMK74923.1 - 1.3e-06 29.5 0.1 0.5 11.5 0.0 4.5 3 1 0 3 3 3 2 Cytochrome c CCP_MauG PF03150.14 AMK74923.1 - 5.8e-06 27.0 3.1 0.012 16.3 0.0 3.0 2 1 0 2 2 2 2 Di-haem cytochrome c peroxidase Cytochrome_CBB3 PF13442.6 AMK74923.1 - 0.001 19.3 0.1 1.1 9.6 0.1 3.0 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AMK74923.1 - 0.011 15.7 0.2 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF1924 PF09086.11 AMK74923.1 - 0.075 13.4 0.2 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Paired_CXXCH_1 PF09699.10 AMK74923.1 - 0.53 10.1 3.8 14 5.5 0.3 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) PEP-CTERM PF07589.11 AMK74924.1 - 0.35 11.0 2.5 0.83 9.8 2.5 1.7 1 0 0 1 1 1 0 PEP-CTERM motif SPOR PF05036.13 AMK74926.1 - 1.1 9.7 4.0 5 7.6 0.3 3.1 3 1 1 4 4 4 0 Sporulation related domain Pan_kinase PF03309.14 AMK74927.1 - 1e-44 152.8 0.1 1.2e-44 152.6 0.1 1.0 1 0 0 1 1 1 1 Type III pantothenate kinase BPL_LplA_LipB PF03099.19 AMK74928.1 - 5.7e-20 71.6 0.0 7.7e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HTH_11 PF08279.12 AMK74928.1 - 3.1e-10 39.8 0.0 6.4e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 HTH domain BPL_C PF02237.17 AMK74928.1 - 9.5e-10 38.2 0.1 2.1e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain HTH_24 PF13412.6 AMK74928.1 - 0.0043 16.6 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_1 PF00126.27 AMK74928.1 - 0.0066 16.4 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 AMK74928.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 AMK74928.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain PilZ PF07238.14 AMK74929.1 - 8.9e-08 32.4 0.0 4.5e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 PilZ domain DrsE PF02635.15 AMK74930.1 - 7.9e-15 55.2 0.0 8.6e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE PF02635.15 AMK74931.1 - 6.1e-23 81.4 0.0 7e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family Peptidase_M48 PF01435.18 AMK74932.1 - 1.9e-33 115.9 0.1 3.4e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 TPR_19 PF14559.6 AMK74932.1 - 1.6e-17 63.7 11.4 7.7e-12 45.5 0.5 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK74932.1 - 5.6e-12 45.4 4.2 0.015 16.1 0.1 4.9 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 AMK74932.1 - 6.7e-10 38.3 4.3 0.0086 16.1 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK74932.1 - 1.8e-08 34.5 5.7 0.0006 20.0 0.3 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AMK74932.1 - 2.9e-08 33.8 10.2 0.00011 22.6 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AMK74932.1 - 1.1e-07 32.4 2.5 0.41 11.3 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 AMK74932.1 - 8e-05 22.3 2.0 0.34 10.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 AMK74932.1 - 0.00014 21.2 3.2 0.00042 19.6 2.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.6 AMK74932.1 - 0.00033 20.5 4.4 0.0005 19.9 3.2 1.9 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_12 PF13424.6 AMK74932.1 - 0.00046 20.4 7.2 0.3 11.4 0.2 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AMK74932.1 - 0.00072 19.8 4.3 4.6 7.8 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AMK74932.1 - 0.0014 18.3 0.0 0.042 13.5 0.0 2.4 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 AMK74932.1 - 0.0016 17.9 1.2 0.0042 16.6 0.2 2.0 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_8 PF13181.6 AMK74932.1 - 0.0019 18.3 5.2 2.6 8.5 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Peptidase_M91 PF14891.6 AMK74932.1 - 0.019 15.3 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Effector protein TPR_18 PF13512.6 AMK74932.1 - 0.029 14.5 2.1 0.067 13.3 2.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 AMK74932.1 - 0.068 12.9 0.3 4.4 7.0 0.0 3.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Wzy_C_2 PF11846.8 AMK74932.1 - 0.17 11.7 5.3 1.2 9.0 0.2 2.8 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 AMK74932.1 - 0.18 11.9 2.9 3.4 7.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 AMK74932.1 - 0.81 9.4 9.8 0.099 12.3 3.4 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain RNA_pol_Rpb6 PF01192.22 AMK74933.1 - 1.8e-14 53.3 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 HD_4 PF13328.6 AMK74934.1 - 4.6e-47 159.6 0.6 8.4e-47 158.8 0.6 1.4 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AMK74934.1 - 4.7e-36 123.6 0.0 1.1e-35 122.5 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AMK74934.1 - 5.1e-19 68.1 0.1 1.1e-18 67.0 0.1 1.6 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AMK74934.1 - 2e-15 57.1 2.1 6.1e-15 55.6 2.1 1.9 1 0 0 1 1 1 1 ACT domain HD PF01966.22 AMK74934.1 - 8.5e-10 38.9 1.7 6.2e-09 36.1 1.2 2.7 2 1 1 3 3 3 1 HD domain ACT PF01842.25 AMK74934.1 - 2.5e-06 27.1 0.8 1.5e-05 24.6 0.8 2.3 2 0 0 2 2 2 1 ACT domain Thiolase_N PF00108.23 AMK74934.1 - 0.097 12.0 0.2 0.69 9.2 0.0 2.2 2 0 0 2 2 2 0 Thiolase, N-terminal domain Ribonuc_L-PSP PF01042.21 AMK74935.1 - 8.3e-40 135.6 0.1 9.3e-40 135.4 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 AMK74935.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.6 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Helicase_C PF00271.31 AMK74936.1 - 3.6e-23 82.0 0.0 2.6e-17 63.2 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecG_wedge PF17191.4 AMK74936.1 - 1.6e-20 73.4 0.0 2.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 RecG wedge domain DEAD PF00270.29 AMK74936.1 - 1.7e-17 63.7 0.2 4.3e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AMK74936.1 - 4.7e-10 39.7 0.0 7.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 AMK74936.1 - 6.4e-07 29.3 0.0 1.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AAA_30 PF13604.6 AMK74936.1 - 3.1e-05 23.8 0.2 5.3e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.23 AMK74936.1 - 0.00031 19.6 0.0 0.00042 19.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdd1 PF11731.8 AMK74936.1 - 0.0018 18.4 0.0 0.073 13.3 0.0 2.4 2 0 0 2 2 2 1 Pathogenicity locus DUF2075 PF09848.9 AMK74936.1 - 0.0035 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IMS_HHH PF11798.8 AMK74936.1 - 0.0068 16.7 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 AMK74936.1 - 0.048 13.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda SecA_DEAD PF07517.14 AMK74936.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain BAF PF02961.14 AMK74936.1 - 0.17 12.4 0.0 0.54 10.7 0.0 1.8 1 0 0 1 1 1 0 Barrier to autointegration factor Chor_lyase PF04345.13 AMK74937.1 - 5.7e-28 97.7 0.0 7.3e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate lyase UTRA PF07702.13 AMK74937.1 - 0.00064 19.6 0.0 0.054 13.3 0.0 2.3 2 0 0 2 2 2 2 UTRA domain zf-TFIIB PF13453.6 AMK74938.1 - 3.6e-17 61.4 2.1 1.2e-10 40.5 0.2 3.2 4 0 0 4 4 4 2 Transcription factor zinc-finger DZR PF12773.7 AMK74938.1 - 3e-05 24.0 11.2 0.0062 16.5 2.5 3.1 3 0 0 3 3 3 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 AMK74938.1 - 0.00031 20.4 2.5 0.00031 20.4 2.5 3.6 4 0 0 4 4 4 1 zinc-ribbon domain UPF0547 PF10571.9 AMK74938.1 - 0.00072 19.6 1.5 0.00072 19.6 1.5 3.5 4 0 0 4 4 4 2 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 AMK74938.1 - 0.00074 19.8 1.0 0.17 12.2 0.4 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding TackOD1 PF18551.1 AMK74938.1 - 0.014 15.1 9.3 0.29 10.8 6.2 3.1 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 AMK74938.1 - 0.063 13.3 9.3 0.14 12.2 5.5 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-NADH-PPase PF09297.11 AMK74938.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.8 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 AMK74938.1 - 2 9.2 13.9 0.27 12.0 2.7 3.5 3 1 0 3 3 3 0 zinc-ribbon family DnaJ_CXXCXGXG PF00684.19 AMK74938.1 - 6.1 7.3 6.6 9 6.8 3.7 2.7 2 1 0 2 2 2 0 DnaJ central domain Band_7_1 PF13421.6 AMK74939.1 - 1.3e-38 132.9 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family Band_7 PF01145.25 AMK74939.1 - 1.3e-07 31.8 0.3 2.5e-07 30.9 0.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family SHOCT PF09851.9 AMK74939.1 - 3.2e-06 26.7 3.8 3.2e-06 26.7 3.8 1.9 2 0 0 2 2 2 1 Short C-terminal domain ArsR PF09824.9 AMK74939.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 ArsR transcriptional regulator GvpG PF05120.12 AMK74939.1 - 0.028 14.4 0.6 0.096 12.7 0.1 2.2 3 0 0 3 3 3 0 Gas vesicle protein G Hexapep PF00132.24 AMK74940.1 - 3.6e-19 67.7 11.3 2.1e-07 30.4 0.8 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AMK74940.1 - 0.0034 17.1 16.1 0.42 10.4 0.7 4.4 3 1 1 4 4 4 4 Hexapeptide repeat of succinyl-transferase FLgD_tudor PF13861.6 AMK74940.1 - 0.15 12.3 0.3 1.9 8.8 1.5 2.1 2 1 0 2 2 2 0 FlgD Tudor-like domain DUF4954 PF16314.5 AMK74940.1 - 0.24 9.5 0.3 0.39 8.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NlpE PF04170.12 AMK74941.1 - 5.5e-20 72.1 0.5 9e-20 71.4 0.5 1.3 1 0 0 1 1 1 1 NlpE N-terminal domain DUF2897 PF11446.8 AMK74942.1 - 0.002 18.0 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2897) CxxCxxCC PF03692.15 AMK74944.1 - 1.8e-07 31.8 11.9 3.2e-07 31.0 11.9 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain FtsX_ECD PF18075.1 AMK74945.1 - 2.2e-18 66.7 1.4 3.6e-18 66.0 1.4 1.3 1 0 0 1 1 1 1 FtsX extracellular domain DUF5518 PF17647.1 AMK74945.1 - 0.0018 18.4 4.7 0.0018 18.4 4.7 2.2 2 1 0 2 2 2 1 Family of unknown function (DUF5518) FtsX PF02687.21 AMK74945.1 - 0.0085 16.5 6.1 0.0085 16.5 6.1 2.9 3 0 0 3 3 3 1 FtsX-like permease family MacB_PCD PF12704.7 AMK74945.1 - 0.95 9.8 3.6 1.1 9.5 1.9 2.0 1 1 0 1 1 1 0 MacB-like periplasmic core domain ABC_tran PF00005.27 AMK74946.1 - 2e-35 122.3 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK74946.1 - 1.1e-08 35.3 0.0 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK74946.1 - 5.4e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK74946.1 - 0.00012 22.1 0.0 0.00027 20.9 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AMK74946.1 - 0.001 19.5 0.0 0.0013 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 AMK74946.1 - 0.0023 17.8 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.6 AMK74946.1 - 0.0083 15.7 0.1 0.077 12.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AMK74946.1 - 0.0092 16.3 0.1 0.023 15.0 0.1 1.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AMK74946.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 AMK74946.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AMK74946.1 - 0.029 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 AMK74946.1 - 0.039 13.9 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 AMK74946.1 - 0.061 13.9 0.0 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AMK74946.1 - 0.065 13.7 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AMK74946.1 - 0.12 11.9 0.0 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AMK74946.1 - 0.16 11.9 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 AMK74947.1 - 1.3e-77 259.8 3.9 2.1e-77 259.2 3.9 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain COX15-CtaA PF02628.15 AMK74947.1 - 3e-72 243.4 13.9 3.8e-72 243.1 13.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein SRP54_N PF02881.19 AMK74947.1 - 9.2e-10 38.6 0.3 2.2e-09 37.4 0.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 AMK74947.1 - 9.6e-09 34.8 0.1 1.9e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 AMK74947.1 - 7.3e-06 25.8 1.0 1.6e-05 24.7 1.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AMK74947.1 - 2.1e-05 24.0 0.4 2.9e-05 23.5 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 AMK74947.1 - 6.4e-05 23.2 0.4 0.0002 21.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 AMK74947.1 - 0.00012 22.0 0.1 0.00034 20.5 0.1 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 AMK74947.1 - 0.00018 21.9 1.1 0.00058 20.3 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 AMK74947.1 - 0.0002 21.8 1.3 0.00042 20.8 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AMK74947.1 - 0.00033 20.8 0.1 0.0006 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK74947.1 - 0.00055 20.5 0.5 0.0014 19.2 0.1 1.8 2 0 0 2 2 2 1 ABC transporter Thymidylate_kin PF02223.17 AMK74947.1 - 0.00073 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Thymidylate kinase AAA PF00004.29 AMK74947.1 - 0.006 17.0 0.2 0.016 15.7 0.2 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) VirC1 PF07015.11 AMK74947.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein MeaB PF03308.16 AMK74947.1 - 0.014 14.4 0.1 0.04 12.9 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 AMK74947.1 - 0.022 14.8 0.1 0.056 13.5 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4560 PF15118.6 AMK74947.1 - 0.028 14.3 1.2 0.076 12.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4560) HXXEE PF13787.6 AMK74947.1 - 0.042 14.6 0.9 0.042 14.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif NTPase_1 PF03266.15 AMK74947.1 - 0.053 13.4 0.7 0.44 10.4 0.3 2.1 1 1 0 2 2 2 0 NTPase MobB PF03205.14 AMK74947.1 - 0.064 13.2 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 AMK74947.1 - 0.073 13.4 0.3 0.22 11.9 0.3 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AMK74947.1 - 0.074 13.6 0.1 0.2 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AMK74947.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AMK74947.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 AMK74947.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 AMK74947.1 - 0.15 12.0 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AMK74947.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 AMK74947.1 - 0.17 11.7 0.3 0.4 10.4 0.2 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 AMK74947.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 AMK74947.1 - 0.17 12.0 0.4 0.39 10.8 0.1 1.8 2 0 0 2 2 1 0 Adenylate kinase KdpD PF02702.17 AMK74947.1 - 0.22 11.0 1.2 3.4 7.1 0.2 2.2 1 1 1 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain Fe-ADH_2 PF13685.6 AMK74947.1 - 0.31 10.7 1.8 1.2 8.8 0.5 2.4 2 1 1 3 3 3 0 Iron-containing alcohol dehydrogenase SCO1-SenC PF02630.14 AMK74948.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC SURF1 PF02104.15 AMK74949.1 - 5.8e-34 117.9 0.0 6.6e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 SURF1 family DUF2909 PF11137.8 AMK74950.1 - 6.7e-20 70.8 4.6 8e-20 70.5 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) Fungus-induced PF10917.8 AMK74950.1 - 0.014 15.7 0.4 1.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Fungus-induced protein T4SS_CagC PF16943.5 AMK74950.1 - 0.034 14.3 0.3 0.043 14.0 0.3 1.1 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system Polysacc_synt_3 PF13440.6 AMK74950.1 - 0.058 12.6 1.2 0.07 12.3 1.2 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1461 PF07314.11 AMK74950.1 - 0.16 11.9 2.5 0.18 11.7 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF3671 PF12420.8 AMK74950.1 - 0.48 10.5 2.0 0.85 9.7 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function COX3 PF00510.18 AMK74951.1 - 9.9e-58 196.0 20.9 3.6e-49 167.9 8.8 2.0 2 0 0 2 2 2 2 Cytochrome c oxidase subunit III CtaG_Cox11 PF04442.14 AMK74952.1 - 1.5e-47 161.4 1.9 1.8e-47 161.1 1.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 COX1 PF00115.20 AMK74953.1 - 4.4e-149 497.0 76.6 5.1e-149 496.8 76.6 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 AMK74954.1 - 5.7e-37 126.3 0.0 1e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 AMK74954.1 - 7.4e-15 54.9 1.0 1.4e-14 54.0 1.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Cytochrome_CBB3 PF13442.6 AMK74954.1 - 1.8e-12 47.4 0.0 4.2e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK74954.1 - 4.3e-08 34.2 0.5 2.1e-05 25.6 0.1 3.2 2 1 1 3 3 3 1 Cytochrome c Cupredoxin_1 PF13473.6 AMK74954.1 - 0.0049 16.9 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Cupredoxin-like domain 7tm_7 PF08395.12 AMK74954.1 - 0.022 14.0 0.2 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Chordopox_A13L PF05961.11 AMK74954.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3679 PF12438.8 AMK74954.1 - 4.3 7.1 6.1 1.7 8.4 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3679) Hemerythrin PF01814.23 AMK74955.1 - 1e-10 42.3 0.3 1.3e-10 42.0 0.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AAA_26 PF13500.6 AMK74956.1 - 3e-35 121.8 0.0 3.6e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK74956.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 AMK74956.1 - 0.00048 19.5 0.8 0.0043 16.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain Methyltransf_11 PF08241.12 AMK74957.1 - 1.6e-20 73.5 0.0 2.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK74957.1 - 1.4e-16 61.0 0.0 2.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK74957.1 - 4.8e-12 46.0 0.0 7.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK74957.1 - 2.9e-10 39.9 0.0 4.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AMK74957.1 - 2.7e-09 37.0 0.0 3.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK74957.1 - 2e-08 34.9 0.0 3.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AMK74957.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AMK74957.1 - 0.0034 17.0 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 AMK74957.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 AMK74958.1 - 1.6e-25 90.2 0.1 2.1e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK74958.1 - 4.8e-22 79.7 2.2 5.4e-22 79.5 2.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK74958.1 - 1.1e-13 51.0 0.1 5.5e-13 48.7 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AMK74958.1 - 2e-10 41.2 0.0 3.2e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 AMK74958.1 - 0.0041 16.9 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 AMK74958.1 - 0.0088 15.7 0.0 0.025 14.2 0.0 1.7 1 1 1 2 2 2 1 Putative esterase DLH PF01738.18 AMK74958.1 - 0.017 14.7 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Aminotran_1_2 PF00155.21 AMK74959.1 - 5.3e-59 200.2 0.0 6e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AMK74959.1 - 0.025 13.8 0.0 0.07 12.4 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AMK74959.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.13 AMK74960.1 - 2.2e-20 72.6 0.1 5.6e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 AMK74960.1 - 5.1e-15 56.2 0.0 8.3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pribosyltran PF00156.27 AMK74961.1 - 2.6e-05 23.8 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AMK74961.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DZR PF12773.7 AMK74961.1 - 1.6 8.8 8.0 6.3 6.9 8.1 1.9 1 1 1 2 2 2 0 Double zinc ribbon CbiA PF01656.23 AMK74962.1 - 1.3e-12 47.9 0.0 4.4e-12 46.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AMK74962.1 - 4.4e-12 46.3 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 AMK74962.1 - 2.8e-10 40.1 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 AMK74962.1 - 1.2e-08 34.8 3.0 3.6e-08 33.2 0.6 2.7 2 1 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AMK74962.1 - 5.2e-08 32.5 0.0 9.9e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AMK74962.1 - 0.0002 20.9 0.2 0.00095 18.7 0.2 1.9 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 AMK74962.1 - 0.0018 17.9 0.3 0.053 13.1 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 AMK74962.1 - 0.0027 16.9 8.3 0.0059 15.8 0.4 3.5 3 1 1 4 4 4 1 Anion-transporting ATPase VirC1 PF07015.11 AMK74962.1 - 0.0046 16.3 1.4 0.023 14.0 0.1 2.3 2 0 0 2 2 2 1 VirC1 protein AAA_24 PF13479.6 AMK74962.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 AMK74962.1 - 0.0089 15.0 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PqqD PF05402.12 AMK74962.1 - 0.015 15.6 0.3 0.069 13.5 0.1 2.4 2 1 0 2 2 1 0 Coenzyme PQQ synthesis protein D (PqqD) Exonuc_VII_L PF02601.15 AMK74962.1 - 0.035 13.7 1.9 0.054 13.0 1.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLP1_P PF16575.5 AMK74962.1 - 0.043 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 AMK74962.1 - 0.085 12.6 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 AMK74962.1 - 0.11 11.8 0.6 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_26 PF13500.6 AMK74962.1 - 0.17 11.7 0.9 0.53 10.1 0.1 2.4 3 1 0 3 3 3 0 AAA domain DnaB_C PF03796.15 AMK74962.1 - 0.29 10.4 0.1 0.29 10.4 0.1 2.3 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 AMK74962.1 - 1.1 8.8 5.3 0.91 9.1 0.1 2.7 3 0 0 3 3 3 0 AAA domain Flavoprotein PF02441.19 AMK74963.1 - 4.2e-13 49.3 0.0 8.8e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 Flavoprotein DUF4346 PF14251.6 AMK74964.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4346) Pterin_bind PF00809.22 AMK74964.1 - 0.0091 15.7 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 1 Pterin binding enzyme PEP_mutase PF13714.6 AMK74964.1 - 0.099 12.1 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase DUF512 PF04459.12 AMK74964.1 - 0.12 11.6 0.0 0.3 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Nitro_FeMo-Co PF02579.17 AMK74965.1 - 1.1e-18 67.3 0.2 1.3e-18 67.1 0.2 1.0 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Radical_SAM PF04055.21 AMK74967.1 - 6.5e-13 49.4 0.2 1.4e-12 48.3 0.2 1.6 1 1 0 1 1 1 1 Radical SAM superfamily DUF4917 PF16263.5 AMK74967.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) DUF1848 PF08902.11 AMK74967.1 - 0.84 9.3 1.8 2.7 7.6 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Aminotran_1_2 PF00155.21 AMK74968.1 - 3.8e-57 194.1 0.0 4.3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AMK74968.1 - 3.1e-08 33.3 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AMK74968.1 - 6.6e-06 24.9 0.0 1.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AMK74968.1 - 0.00054 19.0 0.0 0.00088 18.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V TraC PF07820.12 AMK74968.1 - 0.091 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 TraC-like protein Beta_elim_lyase PF01212.21 AMK74968.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_tran PF00005.27 AMK74969.1 - 6e-18 65.7 0.0 7.5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK74969.1 - 5.5e-11 42.8 1.5 3.5e-05 23.8 0.7 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK74969.1 - 2.5e-06 28.2 0.0 3.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK74969.1 - 1.2e-05 25.8 1.0 3.4e-05 24.3 1.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 AMK74969.1 - 5e-05 23.4 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AMK74969.1 - 7.1e-05 23.1 0.0 0.0002 21.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK74969.1 - 0.00013 21.6 0.1 0.00027 20.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AMK74969.1 - 0.00023 20.7 0.1 0.18 11.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AMK74969.1 - 0.00055 19.9 0.0 0.069 13.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 AMK74969.1 - 0.00081 19.2 0.1 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AMK74969.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase CLP1_P PF16575.5 AMK74969.1 - 0.0014 18.5 0.0 0.0015 18.4 0.0 1.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 AMK74969.1 - 0.003 17.6 0.0 0.067 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AMK74969.1 - 0.0034 17.0 0.2 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 AMK74969.1 - 0.0071 15.8 0.1 0.016 14.6 0.1 1.5 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Zeta_toxin PF06414.12 AMK74969.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.17 AMK74969.1 - 0.013 15.2 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 AMK74969.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AMK74969.1 - 0.015 15.2 0.2 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 AMK74969.1 - 0.036 14.1 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AMK74969.1 - 0.037 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AMK74969.1 - 0.059 13.5 0.0 0.087 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AMK74969.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AMK74969.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 AMK74969.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 AMK74969.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 AMK74969.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 AMK74969.1 - 0.15 12.6 0.2 0.44 11.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AMK74969.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 AMK74969.1 - 0.19 11.5 0.0 2.6 7.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain GTP_cyclohydro2 PF00925.20 AMK74971.1 - 2.6e-72 241.7 0.0 3.3e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II RibD_C PF01872.17 AMK74972.1 - 4.9e-41 140.8 0.0 5.7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain RVT_3 PF13456.6 AMK74972.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like ADH_zinc_N PF00107.26 AMK74973.1 - 7e-09 35.8 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AMK74973.1 - 0.042 14.9 0.0 0.14 13.3 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase PTPS PF01242.19 AMK74974.1 - 8.9e-24 83.8 0.0 9.7e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Glycos_transf_1 PF00534.20 AMK74975.1 - 6.9e-32 110.3 0.0 1.2e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK74975.1 - 3.3e-24 85.8 0.0 5.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK74975.1 - 2.8e-07 30.7 0.4 1.9e-06 28.0 0.4 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK74975.1 - 4.2e-05 24.0 1.7 0.00014 22.4 0.1 2.4 2 2 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AMK74975.1 - 0.0082 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1816 PF08846.10 AMK74976.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) Transposase_mut PF00872.18 AMK74977.1 - 1.5e-120 402.6 0.0 1.8e-120 402.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AMK74977.1 - 1.6e-05 25.2 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 AMK74977.1 - 0.015 15.0 0.0 0.84 9.3 0.0 2.1 1 1 1 2 2 2 0 Transposase AAA_33 PF13671.6 AMK74978.1 - 7.1e-12 45.7 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AMK74978.1 - 2.2e-07 31.5 0.1 1e-06 29.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 AMK74978.1 - 3.7e-06 26.6 0.0 5.8e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 AMK74978.1 - 6.7e-06 26.6 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AMK74978.1 - 0.0015 18.8 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AMK74978.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AMK74978.1 - 0.0023 18.2 0.0 0.0084 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 AMK74978.1 - 0.0026 17.6 0.0 0.41 10.5 0.0 2.1 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 AMK74978.1 - 0.0028 18.0 0.1 0.0028 18.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AMK74978.1 - 0.0037 16.7 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AMK74978.1 - 0.0042 17.1 0.1 0.047 13.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AMK74978.1 - 0.0086 15.8 0.0 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 AMK74978.1 - 0.0095 16.1 0.1 0.082 13.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase DnaB_C PF03796.15 AMK74978.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.6 AMK74978.1 - 0.016 15.6 0.1 0.1 13.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain Hydin_ADK PF17213.3 AMK74978.1 - 0.019 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 AMK74978.1 - 0.023 15.1 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.17 AMK74978.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.5 1 1 0 1 1 1 0 Thymidylate kinase AAA_25 PF13481.6 AMK74978.1 - 0.026 14.1 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AMK74978.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PEPCK_ATP PF01293.20 AMK74978.1 - 0.038 12.7 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RuvB_N PF05496.12 AMK74978.1 - 0.038 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 AMK74978.1 - 0.041 13.2 0.0 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 AMK74978.1 - 0.056 14.0 0.3 0.1 13.1 0.3 1.7 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 AMK74978.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 AMK74978.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 AMK74978.1 - 0.085 12.8 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 AMK74978.1 - 0.089 12.8 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 6PF2K PF01591.18 AMK74978.1 - 0.092 12.0 0.1 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase SRP54 PF00448.22 AMK74978.1 - 0.1 12.2 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 AMK74978.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 AMK74978.1 - 0.15 11.8 0.1 0.23 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Endostatin PF06482.11 AMK74979.1 - 0.00088 18.8 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DUF1554 PF07588.11 AMK74979.1 - 0.0029 17.4 3.5 0.0076 16.1 2.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1554) LPG_synthase_TM PF03706.13 AMK74980.1 - 3.8e-31 108.8 35.6 5e-31 108.4 35.6 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region CP_ATPgrasp_2 PF14403.6 AMK74980.1 - 0.21 10.5 0.1 0.85 8.5 0.0 1.7 2 0 0 2 2 2 0 Circularly permuted ATP-grasp type 2 CDP-OH_P_transf PF01066.21 AMK74981.1 - 1.5e-07 32.1 0.5 1.5e-07 32.1 0.5 3.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Sulfatase PF00884.23 AMK74982.1 - 1.4e-08 34.6 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF3413 PF11893.8 AMK74982.1 - 0.062 12.5 2.1 0.12 11.5 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Penicil_amidase PF01804.18 AMK74983.1 - 8.6e-175 583.5 14.2 9.9e-175 583.3 14.2 1.0 1 0 0 1 1 1 1 Penicillin amidase Cytochrome-c551 PF10643.9 AMK74987.1 - 0.0069 16.0 4.8 0.0069 16.0 4.8 1.3 1 1 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 Holin_2-3 PF13272.6 AMK74987.1 - 0.024 14.9 0.5 0.058 13.7 0.5 1.6 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin DUF2214 PF09980.9 AMK74988.1 - 0.0039 17.0 4.8 0.006 16.4 4.8 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2214) TssN PF17555.2 AMK74988.1 - 0.91 8.9 4.9 1.4 8.2 4.8 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN VirB3 PF05101.13 AMK74988.1 - 4.2 7.7 9.0 0.19 12.0 1.7 2.3 2 1 1 3 3 3 0 Type IV secretory pathway, VirB3-like protein Cytochrom_C_2 PF01322.20 AMK74989.1 - 2.5e-07 31.6 1.0 3.8e-07 31.0 0.9 1.5 1 1 0 1 1 1 1 Cytochrome C' DUF2205 PF10224.9 AMK74989.1 - 0.035 14.1 0.3 0.079 13.0 0.3 1.7 1 0 0 1 1 1 0 Short coiled-coil protein Abhydrolase_6 PF12697.7 AMK74990.1 - 0.0089 16.6 2.3 0.013 16.1 1.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 AMK74990.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 AMK74990.1 - 0.022 14.3 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 AMK74990.1 - 0.041 13.7 0.3 0.1 12.5 0.2 1.6 1 1 0 1 1 1 0 Serine hydrolase DUF3290 PF11694.8 AMK74991.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Abhydrolase_1 PF00561.20 AMK74992.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 AMK74992.1 - 0.0039 17.3 0.0 0.0048 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 AMK74992.1 - 0.0072 17.0 0.3 0.008 16.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 AMK74992.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AMK74992.1 - 0.021 14.1 0.1 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 AMK74992.1 - 0.024 14.5 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 AMK74992.1 - 0.025 14.3 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 AMK74992.1 - 0.056 13.2 0.1 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 AMK74992.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AhpC-TSA PF00578.21 AMK74993.1 - 8.8e-14 51.5 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK74993.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin DsbC PF11412.8 AMK74994.1 - 1.5e-18 66.9 0.0 2.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 AMK74994.1 - 8.2e-17 61.2 0.0 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 AMK74994.1 - 2.4e-06 27.6 10.7 3.8e-06 27.0 10.7 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioredox_DsbH PF03190.15 AMK74994.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PEP-CTERM PF07589.11 AMK74996.1 - 6.7e-06 26.0 0.2 1.8e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 PEP-CTERM motif Collar PF07484.12 AMK74997.1 - 9.9e-24 83.1 0.3 1.9e-23 82.2 0.3 1.5 1 0 0 1 1 1 1 Phage Tail Collar Domain FUN14 PF04930.15 AMK74998.1 - 5.2e-10 39.6 2.8 7e-10 39.2 2.8 1.2 1 0 0 1 1 1 1 FUN14 family Peptidase_M23 PF01551.22 AMK74999.1 - 3.1e-17 62.6 0.0 6e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M23 ABC_membrane PF00664.23 AMK75000.1 - 1.3e-36 126.6 20.5 1.8e-36 126.3 20.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AMK75000.1 - 2.6e-36 124.3 0.0 5.1e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 AMK75000.1 - 1.7e-32 112.8 0.0 3.2e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AMK75000.1 - 5.2e-06 26.1 0.0 1.4e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AMK75000.1 - 0.00062 20.0 0.0 0.031 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AMK75000.1 - 0.00094 19.6 0.0 0.005 17.3 0.0 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AMK75000.1 - 0.0021 17.8 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 AMK75000.1 - 0.0054 17.1 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Peptidase_C70 PF12385.8 AMK75000.1 - 0.0097 15.9 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 AAA_21 PF13304.6 AMK75000.1 - 0.014 15.2 0.3 1.9 8.2 0.4 3.1 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 AMK75000.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AMK75000.1 - 0.033 13.8 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AMK75000.1 - 0.036 14.3 0.2 7.6 6.8 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 AMK75000.1 - 0.045 13.7 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 AMK75000.1 - 0.047 14.2 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AMK75000.1 - 0.053 13.5 0.3 0.39 10.7 0.1 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 AMK75000.1 - 0.056 13.2 0.1 7 6.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 AMK75000.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 AMK75000.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 AMK75000.1 - 0.074 12.8 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 AMK75000.1 - 0.089 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Peptidase_C39_2 PF13529.6 AMK75000.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family Dpy19 PF10034.9 AMK75000.1 - 4 5.5 10.7 15 3.6 10.7 1.8 1 1 0 1 1 1 0 Q-cell neuroblast polarisation HlyD_3 PF13437.6 AMK75001.1 - 6e-18 65.5 6.3 1.1e-13 51.8 1.0 3.0 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK75001.1 - 5.4e-14 51.9 14.1 1.2e-06 27.9 12.5 3.1 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AMK75001.1 - 7.9e-11 41.6 2.4 4.8e-06 26.3 0.0 4.4 4 0 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK75001.1 - 1.8e-07 30.9 0.0 0.036 13.9 0.0 2.9 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.20 AMK75001.1 - 0.00024 20.9 6.8 0.00041 20.2 6.8 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS CSD2 PF17876.1 AMK75001.1 - 0.039 14.1 0.0 0.7 10.1 0.0 2.8 3 0 0 3 3 3 0 Cold shock domain EFG_C PF00679.24 AMK75001.1 - 0.099 12.7 0.3 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Elongation factor G C-terminus COG2 PF06148.11 AMK75001.1 - 0.38 10.8 15.3 0.2 11.7 8.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 AMK75001.1 - 1 9.4 26.8 0.17 11.9 18.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Bacteriocin_IIc PF10439.9 AMK75003.1 - 0.17 12.1 6.3 0.74 10.0 6.0 2.2 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DDE_Tnp_1 PF01609.21 AMK75006.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK75006.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK75006.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK75006.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK75006.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK75006.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK75006.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK75006.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK75006.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK75006.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK75006.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK75006.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK75006.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain TonB_dep_Rec PF00593.24 AMK75007.1 - 6e-16 59.4 31.9 4e-14 53.4 29.3 2.7 1 1 0 1 1 1 1 TonB dependent receptor FecR PF04773.13 AMK75007.1 - 4.3e-13 49.7 0.0 1.8e-12 47.7 0.0 2.2 1 0 0 1 1 1 1 FecR protein TPR_2 PF07719.17 AMK75007.1 - 3.1e-10 39.4 20.0 2.3 8.6 0.4 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75007.1 - 3.4e-05 24.4 0.3 3.4e-05 24.4 0.3 5.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 AMK75007.1 - 4.7e-05 23.8 34.7 0.74 10.4 1.3 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 AMK75007.1 - 0.00025 21.1 26.1 0.00033 20.8 0.1 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat Porin_2 PF02530.14 AMK75007.1 - 0.0022 17.3 2.6 0.0091 15.3 0.2 2.6 2 2 0 2 2 2 1 Porin subfamily TPR_14 PF13428.6 AMK75007.1 - 0.0032 18.2 30.4 1.8 9.6 1.6 7.6 3 2 5 8 8 8 3 Tetratricopeptide repeat ChAPs PF09295.10 AMK75007.1 - 0.013 14.6 1.6 0.031 13.3 1.6 1.5 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 AMK75007.1 - 0.02 14.1 21.3 0.038 13.2 18.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75007.1 - 0.054 13.3 11.5 15 5.6 0.4 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75007.1 - 0.33 10.7 0.0 0.33 10.7 0.0 6.8 8 1 1 9 9 8 0 TPR repeat TPR_17 PF13431.6 AMK75007.1 - 0.87 10.1 14.4 8.8 7.0 0.2 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK75007.1 - 2.4 8.4 8.7 8.5 6.7 2.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Clc-like PF07062.12 AMK75008.1 - 0.07 12.6 0.1 0.12 11.8 0.0 1.4 2 0 0 2 2 2 0 Clc-like CHASE2 PF05226.11 AMK75009.1 - 2.3e-30 106.2 0.0 3.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 CHASE2 domain Guanylate_cyc PF00211.20 AMK75009.1 - 1.3e-21 77.0 0.0 2.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_16 PF13432.6 AMK75009.1 - 0.00076 20.1 1.6 0.0019 18.8 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75009.1 - 0.026 14.6 0.3 0.062 13.4 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75009.1 - 0.062 14.2 1.5 0.39 11.7 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 AMK75011.1 - 2.7e-09 37.4 0.0 3.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 AMK75011.1 - 2.9e-08 34.2 0.0 3.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF5326 PF17260.2 AMK75012.1 - 0.00021 21.4 1.3 0.00025 21.1 1.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5326) DUF639 PF04842.12 AMK75012.1 - 0.032 13.7 0.3 0.033 13.6 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PepSY_TM PF03929.16 AMK75012.1 - 0.047 13.4 0.9 0.063 12.9 0.1 1.5 1 1 0 1 1 1 0 PepSY-associated TM region AAA PF00004.29 AMK75013.1 - 4.6e-15 56.2 0.0 1.3e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK75013.1 - 0.0015 18.9 0.6 0.0069 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 AMK75013.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 AMK75013.1 - 0.11 12.5 0.0 0.39 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AMK75013.1 - 0.13 12.0 0.4 0.45 10.2 0.4 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 AMK75013.1 - 0.16 11.8 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_22 PF13401.6 AMK75013.1 - 0.17 12.2 3.6 0.84 9.9 0.3 3.0 2 1 1 3 3 3 0 AAA domain DVL PF08137.12 AMK75013.1 - 0.59 10.0 2.3 1.6 8.7 2.3 1.8 1 0 0 1 1 1 0 DVL family Fer4_17 PF13534.6 AMK75014.1 - 2.9e-07 30.9 2.8 5.8e-07 30.0 2.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK75014.1 - 3.9e-07 30.4 2.9 7.3e-07 29.5 2.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain ABC_trans_aux PF03886.13 AMK75016.1 - 4.5e-36 123.8 0.3 5.2e-36 123.7 0.3 1.0 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component MlaD PF02470.20 AMK75017.1 - 5.6e-15 55.4 0.1 9.8e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 MlaD protein DUF948 PF06103.11 AMK75017.1 - 2.2e-06 27.8 8.3 6.3e-05 23.2 0.2 3.7 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.14 AMK75017.1 - 0.0041 16.9 7.8 0.0095 15.7 7.8 1.6 1 0 0 1 1 1 1 Laminin Domain I Exo70 PF03081.15 AMK75017.1 - 0.006 15.7 1.4 0.0086 15.2 1.4 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Prominin PF05478.11 AMK75017.1 - 0.064 11.2 3.4 0.11 10.5 3.4 1.3 1 0 0 1 1 1 0 Prominin Med9 PF07544.13 AMK75017.1 - 0.071 13.2 1.1 1.7 8.8 0.3 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Rx_N PF18052.1 AMK75017.1 - 0.098 12.9 1.3 5.9 7.2 0.4 2.6 1 1 0 2 2 2 0 Rx N-terminal domain Spectrin PF00435.21 AMK75017.1 - 0.1 13.1 4.3 0.13 12.8 0.7 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF1071 PF06378.11 AMK75017.1 - 0.17 11.4 0.1 1.4 8.5 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1071) ApoLp-III PF07464.11 AMK75017.1 - 0.23 11.6 3.4 1.4 9.0 2.5 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Laminin_II PF06009.12 AMK75017.1 - 0.25 11.3 8.4 1.2 9.2 2.3 2.9 1 1 1 3 3 3 0 Laminin Domain II SesA PF17107.5 AMK75017.1 - 0.28 11.4 5.8 0.66 10.2 0.4 2.5 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FUSC PF04632.12 AMK75017.1 - 0.48 8.9 4.5 0.46 8.9 3.2 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Mce4_CUP1 PF11887.8 AMK75017.1 - 0.62 9.5 8.0 1.2 8.6 3.7 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DASH_Dam1 PF08653.10 AMK75017.1 - 0.83 9.5 3.3 44 4.0 0.0 3.5 2 1 0 3 3 3 0 DASH complex subunit Dam1 Lebercilin PF15619.6 AMK75017.1 - 0.89 9.2 8.7 0.47 10.1 5.5 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HR1 PF02185.16 AMK75017.1 - 1.2 9.3 11.6 5.1 7.3 0.6 2.9 2 1 1 3 3 3 0 Hr1 repeat AATF-Che1 PF13339.6 AMK75017.1 - 6.5 7.4 9.0 61 4.3 9.0 2.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Baculo_PEP_C PF04513.12 AMK75017.1 - 9.1 6.3 11.1 10 6.2 6.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 AMK75018.1 - 8.1e-26 91.2 0.0 1.1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK75018.1 - 3.6e-10 40.1 0.1 3e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK75018.1 - 0.00031 21.3 0.4 0.00051 20.6 0.4 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AMK75018.1 - 0.00041 20.2 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain ATPase_2 PF01637.18 AMK75018.1 - 0.0051 16.8 0.0 0.0088 16.0 0.0 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 AMK75018.1 - 0.0053 17.1 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AMK75018.1 - 0.0064 16.1 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 AMK75018.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 AMK75018.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 AMK75018.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 AMK75018.1 - 0.015 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 AMK75018.1 - 0.016 14.7 0.3 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 AMK75018.1 - 0.018 15.0 0.4 0.32 11.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AMK75018.1 - 0.022 15.0 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AMK75018.1 - 0.08 13.4 0.2 6.5 7.2 0.2 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK75018.1 - 0.08 13.3 0.0 0.14 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 AMK75018.1 - 0.093 11.5 0.4 0.32 9.7 0.2 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 AMK75018.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AMK75018.1 - 0.13 12.5 0.3 0.43 10.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AMK75018.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MlaE PF02405.16 AMK75019.1 - 1.1e-68 231.1 22.3 1.4e-68 230.7 22.3 1.2 1 0 0 1 1 1 1 Permease MlaE PAS_3 PF08447.12 AMK75020.1 - 5.7e-47 157.9 0.4 8.3e-13 48.4 0.0 4.6 4 0 0 4 4 4 4 PAS fold Response_reg PF00072.24 AMK75020.1 - 4.8e-42 142.6 0.0 6.9e-28 97.1 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AMK75020.1 - 2.6e-27 95.6 0.2 5.1e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AMK75020.1 - 3.2e-21 75.5 0.0 1.5e-11 44.4 0.0 4.7 4 0 0 4 4 4 3 PAS domain PAS PF00989.25 AMK75020.1 - 4.1e-21 75.1 0.6 0.00018 21.4 0.0 4.6 4 0 0 4 4 4 4 PAS fold HisKA PF00512.25 AMK75020.1 - 8.1e-19 67.4 0.0 4.6e-18 65.0 0.0 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AMK75020.1 - 6.1e-18 65.1 3.3 0.0055 16.9 0.0 4.7 4 0 0 4 4 4 4 PAS fold DUF4118 PF13493.6 AMK75020.1 - 6.3e-16 58.1 5.9 1.3e-15 57.1 5.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) Hpt PF01627.23 AMK75020.1 - 7.2e-05 23.0 0.7 7.2e-05 23.0 0.7 2.6 2 0 0 2 2 1 1 Hpt domain PAS_8 PF13188.7 AMK75020.1 - 0.0003 20.8 0.0 0.0017 18.3 0.0 2.4 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AMK75020.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sgf11_N PF18519.1 AMK75020.1 - 0.15 11.6 1.2 0.27 10.8 0.3 1.9 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain Response_reg PF00072.24 AMK75021.1 - 2.1e-24 85.8 0.1 3.5e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AMK75021.1 - 9.3e-09 35.3 0.0 1.8e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain SSB PF00436.25 AMK75022.1 - 3.6e-42 142.6 0.2 4.3e-42 142.4 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AMK75022.1 - 0.022 14.7 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MFS_1 PF07690.16 AMK75023.1 - 1.9e-46 158.6 58.6 7.2e-42 143.6 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AMK75023.1 - 4.9e-10 38.8 37.2 3.4e-07 29.5 16.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AMK75023.1 - 0.00018 20.5 23.8 0.032 13.1 16.5 3.1 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 AMK75023.1 - 0.35 9.2 16.5 0.057 11.8 10.4 2.0 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Methyltransf_20 PF12147.8 AMK75024.1 - 6.1e-152 505.1 0.0 9.6e-152 504.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Hydrolase_4 PF12146.8 AMK75024.1 - 1.1e-64 218.0 0.0 1.7e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Methyltransf_23 PF13489.6 AMK75024.1 - 6.5e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_1 PF00561.20 AMK75024.1 - 7.2e-07 29.1 0.1 1.3e-05 25.0 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK75024.1 - 8.1e-07 29.9 4.6 8.1e-07 29.9 4.6 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.6 AMK75024.1 - 0.065 13.0 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75024.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S9 PF00326.21 AMK75024.1 - 0.11 11.9 0.1 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3530 PF12048.8 AMK75024.1 - 3.7 6.9 5.0 14 5.0 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3530) DSPc PF00782.20 AMK75025.1 - 1.9e-11 43.9 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PAP2_3 PF14378.6 AMK75025.1 - 3.1e-05 23.8 6.4 3.1e-05 23.8 6.4 3.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 AMK75025.1 - 0.0014 18.4 5.5 0.0014 18.4 5.5 2.7 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 AMK75025.1 - 7.5 7.2 8.7 3.6 8.2 4.8 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CTP_transf_1 PF01148.20 AMK75026.1 - 2e-46 158.9 11.4 2.5e-46 158.6 11.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CDP-OH_P_transf PF01066.21 AMK75027.1 - 2.4e-06 28.2 0.5 2.4e-06 28.2 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AMP-binding PF00501.28 AMK75028.1 - 3e-79 266.6 0.0 5e-79 265.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Acyltransferase PF01553.21 AMK75028.1 - 1.6e-21 76.4 0.0 3.6e-21 75.2 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase PP-binding PF00550.25 AMK75028.1 - 5.6e-09 36.2 0.7 1.2e-08 35.2 0.7 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site UvrA_inter PF17760.1 AMK75029.1 - 2.1e-37 127.6 0.0 5.8e-37 126.1 0.0 1.8 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AMK75029.1 - 7.3e-35 119.7 0.0 2.4e-33 114.8 0.0 2.6 2 0 0 2 2 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AMK75029.1 - 8.4e-21 74.9 0.0 0.00034 21.1 0.0 4.5 4 1 0 4 4 4 4 ABC transporter SMC_N PF02463.19 AMK75029.1 - 3e-10 39.9 0.0 0.053 12.9 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AMK75029.1 - 8e-08 31.9 0.4 0.0025 17.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK75029.1 - 2.1e-07 31.5 0.0 0.024 15.0 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 AMK75029.1 - 2.1e-06 28.4 0.8 0.0065 17.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 AMK75029.1 - 1.5e-05 24.9 0.1 0.086 12.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 AMK75029.1 - 2.8e-05 24.4 0.9 0.35 11.1 0.0 3.5 4 0 0 4 4 3 2 AAA domain DnaJ_CXXCXGXG PF00684.19 AMK75029.1 - 0.00021 21.6 3.1 0.15 12.4 0.1 3.7 3 1 0 3 3 3 1 DnaJ central domain APS_kinase PF01583.20 AMK75029.1 - 0.00051 20.0 0.1 1.2 9.0 0.0 3.4 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_18 PF13238.6 AMK75029.1 - 0.00053 20.5 0.4 2.5 8.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 AMK75029.1 - 0.001 19.1 0.0 3.9 7.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain cobW PF02492.19 AMK75029.1 - 0.0021 17.6 0.7 0.18 11.3 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 AMK75029.1 - 0.0023 18.1 0.1 3.4 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AMK75029.1 - 0.0036 16.9 0.0 0.42 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AMK75029.1 - 0.0037 17.0 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 AMK75029.1 - 0.006 16.0 0.0 3 7.1 0.0 2.5 2 0 0 2 2 2 1 KaiC DUF2075 PF09848.9 AMK75029.1 - 0.0074 15.6 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 AMK75029.1 - 0.0097 15.7 10.0 0.13 12.1 0.1 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 AMK75029.1 - 0.015 15.0 0.2 5 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain BCA_ABC_TP_C PF12399.8 AMK75029.1 - 0.024 14.6 0.0 7.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter NACHT PF05729.12 AMK75029.1 - 0.026 14.5 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 AMK75029.1 - 0.028 14.1 0.1 8.7 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 AMK75029.1 - 0.04 13.0 0.1 5.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 AMK75029.1 - 0.053 13.6 0.4 4.3 7.5 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DiS_P_DiS PF06750.13 AMK75029.1 - 0.066 13.3 0.2 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain ATPase_2 PF01637.18 AMK75029.1 - 0.085 12.8 0.0 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 AMK75029.1 - 0.095 12.0 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 AMK75029.1 - 0.21 11.8 0.3 35 4.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.10 AMK75029.1 - 1.8 8.8 8.2 0.16 12.1 0.5 2.9 3 0 0 3 3 2 0 Zinc ribbon domain SnoaL_3 PF13474.6 AMK75030.1 - 1.4e-07 31.8 1.4 1.8e-07 31.4 1.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AMK75030.1 - 4.4e-05 23.8 0.3 5.9e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AMK75030.1 - 0.00011 22.8 0.1 0.00015 22.3 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AMK75030.1 - 0.0039 17.3 0.7 0.012 15.8 0.7 1.7 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain YCII PF03795.14 AMK75031.1 - 3.9e-16 59.2 0.0 4.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Metallophos_2 PF12850.7 AMK75032.1 - 1.8e-31 109.6 0.0 2.2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AMK75032.1 - 0.022 15.2 0.8 3 8.3 0.0 2.5 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Acetyltransf_2 PF00797.17 AMK75033.1 - 1.5e-66 224.6 0.0 1.7e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Uma2 PF05685.12 AMK75035.1 - 2.1e-34 118.6 0.5 2.6e-34 118.3 0.5 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease GGDEF PF00990.21 AMK75036.1 - 9.2e-44 149.0 1.6 1.3e-43 148.5 0.3 1.9 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain AIP3 PF03915.13 AMK75036.1 - 0.004 16.3 5.5 0.004 16.3 5.5 1.4 2 0 0 2 2 2 1 Actin interacting protein 3 DUF2381 PF09544.10 AMK75036.1 - 0.012 15.2 0.5 0.022 14.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) FliJ PF02050.16 AMK75036.1 - 0.021 15.0 4.8 0.66 10.2 0.7 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 AMK75036.1 - 0.036 13.4 5.2 0.058 12.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNase_E_G PF10150.9 AMK75036.1 - 0.057 12.8 8.1 0.084 12.3 1.0 2.9 1 1 2 3 3 3 0 Ribonuclease E/G family DUF2353 PF09789.9 AMK75036.1 - 0.061 12.7 8.3 0.024 14.0 5.5 1.7 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1848 PF08902.11 AMK75036.1 - 0.15 11.7 3.8 0.32 10.7 2.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) CorA PF01544.18 AMK75036.1 - 0.29 10.4 5.4 0.16 11.2 3.4 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein COG5 PF10392.9 AMK75036.1 - 0.36 11.0 8.7 0.078 13.2 2.9 2.3 2 1 1 3 3 3 0 Golgi transport complex subunit 5 V-SNARE PF05008.15 AMK75036.1 - 0.48 10.8 5.9 0.64 10.4 4.6 1.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus YtxH PF12732.7 AMK75036.1 - 0.68 10.5 2.2 4.7 7.8 1.7 2.6 2 1 0 2 2 2 0 YtxH-like protein THOC7 PF05615.13 AMK75036.1 - 0.9 9.8 10.9 0.12 12.7 6.5 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 SPX PF03105.19 AMK75036.1 - 1.6 8.6 6.5 0.4 10.5 3.5 1.5 2 1 0 2 2 2 0 SPX domain DHR10 PF18595.1 AMK75036.1 - 2 8.5 11.0 1.8e+02 2.2 11.0 2.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3450 PF11932.8 AMK75036.1 - 2.3 7.4 9.9 4.3 6.6 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 AMK75036.1 - 3.6 8.1 9.0 14 6.2 9.0 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Sec8_exocyst PF04048.14 AMK75036.1 - 4.1 7.3 14.3 0.5 10.3 4.7 2.9 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain SDF PF00375.18 AMK75037.1 - 9.8e-119 396.8 36.7 1.1e-118 396.7 36.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family UPF0225 PF17775.1 AMK75038.1 - 1.4e-26 93.2 0.4 1.7e-26 92.9 0.4 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AMK75038.1 - 7.1e-15 54.6 16.9 1.2e-07 31.5 8.0 2.4 2 0 0 2 2 2 2 SEC-C motif SLT_L PF14718.6 AMK75038.1 - 0.03 14.4 0.5 0.27 11.4 0.5 2.0 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain SpoU_methylase PF00588.19 AMK75039.1 - 2e-34 118.8 0.0 2.3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Malate_DH PF12434.8 AMK75039.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Phosphorylase PF00343.20 AMK75040.1 - 0 1089.4 0.0 0 1089.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase SecA_DEAD PF07517.14 AMK75041.1 - 2.5e-132 440.5 2.6 4.3e-132 439.8 2.6 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 AMK75041.1 - 2e-68 230.4 10.8 5e-68 229.1 10.3 2.0 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AMK75041.1 - 2.6e-38 131.1 1.5 4.4e-38 130.4 0.2 2.1 2 0 0 2 2 2 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AMK75041.1 - 1.1e-10 41.2 10.2 1.9e-10 40.4 10.2 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 AMK75041.1 - 0.0005 19.9 0.8 0.0018 18.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK75041.1 - 0.011 16.1 1.8 0.046 14.1 0.0 2.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain TrkA_N PF02254.18 AMK75042.1 - 1.3e-48 164.1 4.8 1e-26 93.5 0.6 2.4 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 AMK75042.1 - 5.5e-15 55.0 3.8 6.7e-07 29.1 0.1 3.7 4 0 0 4 4 4 2 TrkA-C domain NAD_binding_7 PF13241.6 AMK75042.1 - 2.7e-10 40.6 0.9 0.001 19.5 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AMK75042.1 - 1.5e-07 31.7 1.7 0.00017 21.9 0.6 2.4 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 AMK75042.1 - 4.1e-05 24.1 4.6 0.029 14.9 0.2 3.8 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 AMK75042.1 - 4.7e-05 23.0 0.3 0.0094 15.5 0.2 3.1 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 AMK75042.1 - 5.4e-05 23.3 1.3 0.054 13.6 0.4 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 AMK75042.1 - 5.5e-05 23.2 0.5 0.53 10.2 0.0 3.1 3 1 1 4 4 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 AMK75042.1 - 0.0001 22.8 1.1 0.006 17.1 0.3 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 AMK75042.1 - 0.00015 21.5 0.6 0.0017 18.0 0.1 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 AMK75042.1 - 0.00016 21.0 2.4 0.013 14.8 1.6 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AMK75042.1 - 0.00043 20.2 1.2 0.017 15.0 0.3 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 AMK75042.1 - 0.00045 19.8 1.7 0.0023 17.5 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1188) DAO PF01266.24 AMK75042.1 - 0.00056 19.6 0.6 0.0028 17.3 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AMK75042.1 - 0.00062 20.0 0.7 0.0088 16.3 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AMK75042.1 - 0.00084 18.6 1.7 0.017 14.4 1.7 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase mCpol PF18182.1 AMK75042.1 - 0.006 16.9 0.1 3.6 8.0 0.0 3.3 2 1 1 3 3 3 1 minimal CRISPR polymerase domain Peptidase_S24 PF00717.23 AMK75042.1 - 0.0095 15.9 0.5 1.6 8.8 0.0 3.4 3 0 0 3 3 3 1 Peptidase S24-like PglD_N PF17836.1 AMK75042.1 - 0.011 16.4 4.7 0.31 11.7 0.3 3.2 3 0 0 3 3 3 0 PglD N-terminal domain XdhC_C PF13478.6 AMK75042.1 - 0.012 16.2 0.1 5.1 7.6 0.1 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 AMK75042.1 - 0.032 13.6 0.7 2.3 7.5 0.1 2.5 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AMK75042.1 - 0.044 14.0 1.3 0.61 10.2 0.2 2.8 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase YflT PF11181.8 AMK75042.1 - 0.084 13.4 0.3 2.7 8.6 0.0 2.5 1 1 1 2 2 2 0 Heat induced stress protein YflT FUSC PF04632.12 AMK75043.1 - 0.86 8.1 6.5 0.9 8.0 6.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 AMK75043.1 - 2.1 7.9 9.7 2.5 7.6 9.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tetraspanin PF00335.20 AMK75044.1 - 0.046 13.4 0.4 0.053 13.2 0.4 1.2 1 0 0 1 1 1 0 Tetraspanin family LepB_GAP_N PF18172.1 AMK75044.1 - 0.089 12.7 0.5 0.16 11.8 0.4 1.4 1 1 0 1 1 1 0 LepB GAP domain N-terminal subdomain Phage_holin_3_6 PF07332.11 AMK75044.1 - 0.54 10.3 13.3 1.3 9.1 13.3 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2157 PF09925.9 AMK75044.1 - 0.82 9.5 11.2 1.1 9.0 11.2 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF373 PF04123.13 AMK75044.1 - 3.2 7.1 5.1 4.7 6.5 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyoxalase PF00903.25 AMK75045.1 - 2.3e-11 44.0 0.0 4.6e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AMK75045.1 - 1.5e-06 28.5 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AMK75045.1 - 0.0017 19.1 0.0 0.002 18.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AMK75045.1 - 0.035 14.2 0.1 0.064 13.4 0.1 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain AP_endonuc_2 PF01261.24 AMK75046.1 - 1.9e-24 86.3 0.0 2.3e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NAD_binding_2 PF03446.15 AMK75047.1 - 1.5e-42 145.5 1.4 2.1e-42 145.0 1.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AMK75047.1 - 1.5e-25 89.8 0.1 3.3e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AMK75047.1 - 2.9e-07 31.0 0.4 2.9e-07 31.0 0.4 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AMK75047.1 - 2.2e-06 27.2 0.1 3.7e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 AMK75047.1 - 0.0071 16.0 0.4 0.017 14.8 0.2 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 AMK75047.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 AMK75047.1 - 0.067 13.1 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRA-PH PF01503.17 AMK75048.1 - 0.005 17.2 0.0 0.025 15.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase FMN_bind PF04205.14 AMK75050.1 - 0.00027 21.5 0.0 0.00051 20.6 0.0 1.5 1 0 0 1 1 1 1 FMN-binding domain IAT_beta PF11924.8 AMK75051.1 - 0.0043 16.5 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Inverse autotransporter, beta-domain SlyX PF04102.12 AMK75051.1 - 0.14 12.8 4.1 0.61 10.7 4.1 2.0 1 1 0 1 1 1 0 SlyX DUF948 PF06103.11 AMK75051.1 - 0.4 11.0 1.3 1.2 9.4 1.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GIY-YIG PF01541.24 AMK75052.1 - 9.2e-17 61.1 0.0 1e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain ATP-synt_I PF03899.15 AMK75053.1 - 0.15 12.4 8.4 0.19 12.1 8.4 1.1 1 0 0 1 1 1 0 ATP synthase I chain Phage_holin_3_6 PF07332.11 AMK75053.1 - 1.7 8.8 6.3 2.7 8.1 6.3 1.4 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RNase_H PF00075.24 AMK75054.1 - 1.7e-50 171.0 0.1 1.8e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 RNase H Methyltransf_11 PF08241.12 AMK75055.1 - 2.1e-07 31.5 0.0 4.6e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK75055.1 - 8.3e-05 22.0 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AMK75055.1 - 0.002 18.8 0.0 0.0042 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75055.1 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AMK75055.1 - 0.025 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_12 PF08242.12 AMK75055.1 - 0.027 15.2 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75055.1 - 0.037 13.9 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LysM PF01476.20 AMK75056.1 - 1.4e-39 133.9 7.5 5.4e-15 55.2 0.3 4.4 4 0 0 4 4 4 3 LysM domain SLT PF01464.20 AMK75056.1 - 8.4e-25 86.7 0.0 1.8e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain OapA PF04225.12 AMK75056.1 - 8.1e-07 29.1 0.8 0.0048 17.0 0.0 3.3 3 0 0 3 3 3 2 Opacity-associated protein A LysM-like domain HRDC PF00570.23 AMK75056.1 - 0.083 12.9 0.0 7 6.7 0.0 2.9 3 0 0 3 3 3 0 HRDC domain tRNA-synt_1c PF00749.21 AMK75057.1 - 5.8e-109 363.8 0.0 7.2e-109 363.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Sel1 PF08238.12 AMK75058.1 - 1.4e-16 60.5 9.3 4.8e-08 33.4 2.2 2.9 3 0 0 3 3 3 2 Sel1 repeat DUF3775 PF12616.8 AMK75058.1 - 0.012 15.7 0.3 0.11 12.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) RlmM_FDX PF18125.1 AMK75058.1 - 0.012 16.1 0.8 0.042 14.3 0.0 2.2 3 0 0 3 3 3 0 RlmM ferredoxin-like domain Defensin_propep PF00879.18 AMK75058.1 - 0.022 15.0 0.2 0.049 13.9 0.2 1.6 1 0 0 1 1 1 0 Defensin propeptide OmpA PF00691.20 AMK75059.1 - 1.2e-24 86.5 0.0 2.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 OmpA family VWA_2 PF13519.6 AMK75059.1 - 2.2e-07 31.5 0.0 5.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_3 PF02412.18 AMK75059.1 - 0.022 14.5 2.5 0.022 14.5 2.5 2.3 2 0 0 2 2 2 0 Thrombospondin type 3 repeat VWA_3 PF13768.6 AMK75059.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 AMK75059.1 - 0.11 11.8 0.1 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DNA_pol3_alpha PF07733.12 AMK75060.1 - 1.3e-105 352.7 0.0 2e-105 352.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AMK75060.1 - 2.8e-62 208.9 0.0 4.9e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 AMK75060.1 - 4.4e-42 144.2 0.0 1.5e-41 142.5 0.0 2.0 2 0 0 2 2 2 1 PHP domain HHH_6 PF14579.6 AMK75060.1 - 6.1e-27 93.7 0.0 1.6e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 AMK75060.1 - 9.9e-07 28.7 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Bac_A_amyl_C PF18612.1 AMK75060.1 - 0.024 14.4 0.0 0.082 12.7 0.0 1.9 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain RNase_HII PF01351.18 AMK75061.1 - 5.6e-38 130.8 0.0 6.4e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Acetyltransf_11 PF13720.6 AMK75062.1 - 4.2e-28 97.6 0.0 8e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 AMK75062.1 - 3e-26 90.1 5.1 4.4e-09 35.7 0.3 5.5 2 2 5 7 7 7 7 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AMK75062.1 - 0.0053 16.5 5.5 2.5 7.9 0.1 4.0 2 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase FabA PF07977.13 AMK75063.1 - 2.5e-37 127.6 0.0 2.9e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain AfsA PF03756.13 AMK75063.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.3 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain MaoC_dehydratas PF01575.19 AMK75063.1 - 0.06 12.9 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain 4HBT PF03061.22 AMK75063.1 - 0.098 13.0 0.0 0.17 12.3 0.0 1.5 1 1 0 1 1 1 0 Thioesterase superfamily OmpH PF03938.14 AMK75064.1 - 3.5e-25 89.0 8.9 4e-25 88.8 8.9 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 AMK75064.1 - 2.1 7.7 16.6 0.54 9.6 9.8 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) POTRA PF07244.15 AMK75065.1 - 6e-65 215.8 28.1 3.4e-18 66.0 2.5 5.8 6 0 0 6 6 6 5 Surface antigen variable number repeat Bac_surface_Ag PF01103.23 AMK75065.1 - 1.6e-58 198.8 16.3 1.6e-58 198.8 16.3 2.3 3 0 0 3 3 3 1 Surface antigen POTRA_1 PF08478.10 AMK75065.1 - 3.2e-10 40.1 2.5 1.4 9.3 0.0 6.3 7 1 0 7 7 7 4 POTRA domain, FtsQ-type POTRA_2 PF08479.11 AMK75065.1 - 4.9e-06 26.3 2.4 0.091 12.6 0.0 5.0 4 1 0 4 4 4 1 POTRA domain, ShlB-type YqfD PF06898.11 AMK75065.1 - 0.4 9.5 10.3 0.039 12.8 0.8 3.2 3 1 1 4 4 4 0 Putative stage IV sporulation protein YqfD FCSD-flav_bind PF09242.11 AMK75066.1 - 3.5e-20 72.1 0.0 9.6e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Flavocytochrome c sulphide dehydrogenase, flavin-binding Pyr_redox_2 PF07992.14 AMK75066.1 - 2.5e-10 40.1 0.0 7.6e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AMK75066.1 - 0.00011 22.3 0.4 0.0023 18.1 0.1 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK75066.1 - 0.00018 21.2 0.1 0.0051 16.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AMK75066.1 - 0.007 16.4 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 AMK75066.1 - 0.0078 15.5 0.9 0.017 14.5 0.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 AMK75066.1 - 0.0083 16.7 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TAT_signal PF10518.9 AMK75066.1 - 0.012 15.5 3.1 0.012 15.5 3.1 2.2 2 0 0 2 2 1 0 TAT (twin-arginine translocation) pathway signal sequence NAD_binding_7 PF13241.6 AMK75066.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 AMK75066.1 - 0.019 14.2 0.0 0.04 13.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 AMK75066.1 - 0.026 13.4 0.1 0.04 12.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 AMK75066.1 - 0.1 11.7 0.1 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 AMK75066.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Mqo PF06039.15 AMK75066.1 - 0.22 10.0 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 AMK75066.1 - 0.24 10.6 0.3 2.2 7.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Cytochrome_CBB3 PF13442.6 AMK75067.1 - 6.3e-06 26.4 0.0 7.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK75067.1 - 0.00098 20.2 1.1 0.059 14.5 1.1 2.1 1 1 0 1 1 1 1 Cytochrome c SpoU_methylase PF00588.19 AMK75068.1 - 3e-42 144.2 0.0 4.3e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 AMK75068.1 - 3.7e-17 62.4 0.1 8.9e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding RNB PF00773.19 AMK75069.1 - 3.8e-105 351.8 0.0 5.4e-105 351.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain CSD2 PF17876.1 AMK75069.1 - 2e-26 92.0 0.2 1.4e-24 86.1 0.2 2.7 2 0 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 AMK75069.1 - 3.8e-21 74.5 1.6 8.2e-19 67.0 0.0 3.3 4 0 0 4 4 4 2 Ribonuclease B OB domain S1 PF00575.23 AMK75069.1 - 5.2e-12 45.9 0.8 1.7e-11 44.3 0.4 2.2 2 0 0 2 2 2 1 S1 RNA binding domain HTH_12 PF08461.10 AMK75069.1 - 2.5e-08 33.7 1.3 7.3e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain DUF1327 PF07041.11 AMK75069.1 - 0.00086 19.3 0.1 0.0071 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1327) OB_Dis3 PF17849.1 AMK75069.1 - 0.0017 18.4 0.0 0.0081 16.2 0.0 2.1 1 1 1 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD PF00313.22 AMK75069.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain RNase_II_C_S1 PF18614.1 AMK75069.1 - 0.13 12.2 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain TrkA_C PF02080.21 AMK75070.1 - 0.015 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain MgtE_N PF03448.17 AMK75071.1 - 0.03 14.9 2.7 0.13 12.9 2.1 2.0 1 1 0 1 1 1 0 MgtE intracellular N domain DUF1133 PF06576.11 AMK75071.1 - 0.05 13.0 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) DUF1134 PF06577.12 AMK75072.1 - 3.3e-05 23.7 0.5 5e-05 23.1 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1134) DUF748 PF05359.11 AMK75073.1 - 3.3e-92 306.5 7.6 1.4e-33 116.2 1.0 3.7 3 0 0 3 3 3 3 Domain of Unknown Function (DUF748) AsmA PF05170.14 AMK75073.1 - 3.2e-09 36.1 2.6 0.0048 15.8 0.0 3.4 3 0 0 3 3 3 3 AsmA family OmpA PF00691.20 AMK75073.1 - 0.00038 20.8 0.0 0.46 10.9 0.0 2.5 2 0 0 2 2 2 2 OmpA family Dicty_CAD PF05720.12 AMK75073.1 - 0.13 12.3 0.0 0.55 10.3 0.0 2.1 1 0 0 1 1 1 0 Cell-cell adhesion domain S4 PF01479.25 AMK75075.1 - 3.4e-14 52.3 0.0 7e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ring_hydroxyl_B PF00866.18 AMK75075.1 - 0.0043 17.1 0.5 0.0057 16.7 0.5 1.3 1 0 0 1 1 1 1 Ring hydroxylating beta subunit S4_2 PF13275.6 AMK75075.1 - 0.025 14.4 0.3 0.06 13.2 0.1 1.7 1 1 1 2 2 2 0 S4 domain Rhodanese PF00581.20 AMK75076.1 - 5.6e-18 65.4 0.0 7.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain LYTB PF02401.18 AMK75077.1 - 4.7e-94 314.5 1.2 5.4e-94 314.3 1.2 1.0 1 0 0 1 1 1 1 LytB protein RraA-like PF03737.15 AMK75078.1 - 2.1e-37 128.6 0.0 2.3e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Aldolase/RraA Peptidase_U32 PF01136.19 AMK75079.1 - 1.7e-98 328.4 0.0 4.9e-98 326.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family U32 Peptidase_U32_C PF16325.5 AMK75079.1 - 8.2e-21 74.1 0.0 3e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family U32 C-terminal domain Tachystatin_B PF11478.8 AMK75079.1 - 0.076 13.0 1.2 0.15 12.0 1.2 1.4 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Glyco_trans_1_4 PF13692.6 AMK75080.1 - 2.9e-17 63.3 0.5 1.2e-16 61.3 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK75080.1 - 2.8e-13 49.7 0.1 2.7e-12 46.6 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK75080.1 - 1.5e-11 45.0 0.0 3.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AMK75080.1 - 0.00019 21.5 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK75080.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 PLDc_2 PF13091.6 AMK75080.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 PLD-like domain Glycos_transf_1 PF00534.20 AMK75081.1 - 2.9e-15 56.2 0.0 5.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK75081.1 - 1.7e-07 31.7 0.0 5.3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2917 PF11142.8 AMK75081.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Acyl_transf_3 PF01757.22 AMK75082.1 - 3.2e-15 56.0 25.1 4.3e-15 55.6 25.1 1.1 1 0 0 1 1 1 1 Acyltransferase family TssN PF17555.2 AMK75082.1 - 0.0088 15.5 2.8 0.0088 15.5 2.8 2.9 2 1 1 3 3 3 1 Type VI secretion system, TssN Glycos_transf_2 PF00535.26 AMK75083.1 - 7.7e-21 74.6 0.1 1.2e-20 74.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK75083.1 - 3.2e-09 36.6 0.2 2.4e-08 33.8 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AMK75083.1 - 1.9e-08 34.5 0.0 7.3e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK75083.1 - 1.5e-05 25.4 0.0 2.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 AMK75084.1 - 3e-06 27.1 0.5 7.6e-06 25.8 0.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AMK75084.1 - 0.0012 19.3 0.1 0.0032 17.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK75084.1 - 0.006 16.5 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 YesK PF14150.6 AMK75084.1 - 0.094 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 YesK-like protein Sensor_TM1 PF13755.6 AMK75085.1 - 0.009 15.7 0.3 0.033 13.9 0.3 2.0 1 0 0 1 1 1 1 Sensor N-terminal transmembrane domain Methyltransf_21 PF05050.12 AMK75086.1 - 3.3e-12 46.8 0.0 4.3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Epimerase PF01370.21 AMK75087.1 - 1.2e-13 51.1 0.0 1.5e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK75087.1 - 2.4e-06 27.2 0.0 3.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TPP_enzyme_C PF02775.21 AMK75088.1 - 4.7e-41 140.1 0.0 2.7e-38 131.1 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 AMK75088.1 - 7.7e-40 136.3 0.1 6.3e-39 133.3 0.0 2.6 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AMK75088.1 - 1.2e-29 102.8 0.0 3.9e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DegT_DnrJ_EryC1 PF01041.17 AMK75089.1 - 9.7e-115 383.7 0.0 1.3e-114 383.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AMK75089.1 - 5.6e-07 28.8 0.0 3.3e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 AMK75089.1 - 6.6e-06 25.5 0.0 9.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AMK75089.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AMK75089.1 - 6.5e-05 21.6 0.0 8.9e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RBDV_coat PF06593.11 AMK75089.1 - 0.038 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein GDP_Man_Dehyd PF16363.5 AMK75090.1 - 4.1e-34 118.5 0.0 2.5e-33 115.9 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AMK75090.1 - 2.8e-27 95.7 0.0 3.9e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 AMK75090.1 - 2e-16 60.0 0.0 8.3e-16 58.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AMK75090.1 - 8.3e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AMK75090.1 - 1.8e-06 27.1 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AMK75090.1 - 0.0013 17.9 0.2 0.0056 15.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NTP_transferase PF00483.23 AMK75091.1 - 6.4e-17 62.0 0.0 1.2e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AMK75091.1 - 3.5e-07 30.7 0.0 7.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AMK75091.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.26 AMK75092.1 - 4.8e-23 81.8 0.0 7.4e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK75092.1 - 3.9e-12 46.6 0.0 1.1e-11 45.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK75092.1 - 8.9e-12 45.1 0.1 3.2e-11 43.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_25 PF13649.6 AMK75092.1 - 0.00024 21.7 0.0 0.00068 20.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75092.1 - 0.0063 16.4 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75092.1 - 0.013 16.2 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 AMK75092.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF2780 PF11075.8 AMK75092.1 - 0.22 11.6 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) Glycos_transf_2 PF00535.26 AMK75093.1 - 1e-32 113.3 0.2 2.2e-32 112.2 0.1 1.6 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK75093.1 - 1.9e-22 80.1 0.4 2.5e-22 79.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AMK75093.1 - 3.2e-18 66.5 0.1 6.9e-18 65.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK75093.1 - 7.5e-05 23.2 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AMK75093.1 - 0.0001 22.3 0.1 0.00019 21.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Methyltransf_24 PF13578.6 AMK75094.1 - 3.7e-07 31.1 0.0 5.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75094.1 - 0.00041 20.2 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AMK75094.1 - 0.00057 19.5 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CmcI PF04989.12 AMK75094.1 - 0.0048 16.6 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_32 PF13679.6 AMK75094.1 - 0.041 13.9 0.0 0.055 13.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 AMK75094.1 - 0.096 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 AMK75094.1 - 0.12 13.1 0.0 0.23 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TylF PF05711.11 AMK75095.1 - 2e-18 66.6 0.0 2.7e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 AMK75095.1 - 1.5e-05 26.0 0.0 2.9e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DNA_alkylation PF08713.11 AMK75095.1 - 0.091 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme Asn_synthase PF00733.21 AMK75096.1 - 1.9e-75 254.7 0.0 2.5e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AMK75096.1 - 2.7e-40 137.1 0.0 4.9e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AMK75096.1 - 4.8e-36 123.9 0.0 4e-35 120.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 AMK75096.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 AMK75096.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Methyltransf_23 PF13489.6 AMK75097.1 - 0.04 13.8 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75097.1 - 0.059 14.1 0.0 0.37 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75098.1 - 6.3e-13 49.2 0.0 9.4e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75098.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75098.1 - 3.8e-10 40.3 0.0 6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75098.1 - 2.4e-08 34.0 0.0 7.5e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75098.1 - 1.8e-07 31.8 0.0 2.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AMK75098.1 - 0.039 12.9 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FAST_1 PF06743.15 AMK75098.1 - 0.062 13.2 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Wzt_C PF14524.6 AMK75099.1 - 6.3e-20 71.7 0.2 1.4e-19 70.6 0.2 1.5 1 0 0 1 1 1 1 Wzt C-terminal domain ABC_tran PF00005.27 AMK75099.1 - 1.3e-18 67.8 0.0 5.2e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK75099.1 - 0.00014 21.8 1.2 0.00079 19.3 0.2 2.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AMK75099.1 - 0.0024 17.6 2.0 0.018 14.8 2.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AMK75099.1 - 0.0055 17.2 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AMK75099.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase NTPase_1 PF03266.15 AMK75099.1 - 0.017 15.0 1.0 1.2 9.0 0.5 2.4 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 AMK75099.1 - 0.028 14.7 0.1 0.32 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AMK75099.1 - 0.031 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3584 PF12128.8 AMK75099.1 - 0.069 10.7 0.1 0.1 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.12 AMK75099.1 - 0.077 12.9 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 AMK75099.1 - 0.079 12.1 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 AMK75099.1 - 0.088 13.2 0.2 0.38 11.2 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AMK75099.1 - 0.11 12.6 0.3 0.25 11.4 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AMK75099.1 - 0.11 12.0 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AMK75099.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 AMK75099.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 AMK75100.1 - 1.6e-16 60.4 15.4 1.6e-16 60.4 15.4 1.4 1 1 1 2 2 2 1 ABC-2 type transporter Glyco_trans_1_4 PF13692.6 AMK75101.1 - 3.2e-09 37.3 0.0 6.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK75101.1 - 2.8e-08 33.5 0.0 4.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AMK75101.1 - 3.8e-06 27.2 0.0 9.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK75101.1 - 0.0044 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 HTH_AraC PF00165.23 AMK75101.1 - 0.011 15.9 0.3 0.031 14.4 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF1192 PF06698.11 AMK75102.1 - 0.031 14.3 1.4 1.2 9.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) YicC_N PF03755.13 AMK75102.1 - 0.035 14.6 3.2 0.06 13.8 3.2 1.4 1 1 0 1 1 1 0 YicC-like family, N-terminal region Baculo_PEP_C PF04513.12 AMK75102.1 - 0.059 13.4 6.9 0.78 9.8 0.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nsp1_C PF05064.13 AMK75102.1 - 0.12 12.2 4.0 0.16 11.8 0.5 2.4 1 1 1 3 3 3 0 Nsp1-like C-terminal region DUF948 PF06103.11 AMK75102.1 - 0.16 12.3 5.1 3.9 7.8 1.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MRPL52 PF18699.1 AMK75102.1 - 0.32 11.2 4.8 0.89 9.8 2.0 2.4 1 1 2 3 3 3 0 Mitoribosomal protein mL52 ACCA PF03255.14 AMK75102.1 - 0.4 10.6 4.5 0.52 10.2 1.6 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.12 AMK75102.1 - 1 9.4 9.2 7.4 6.6 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Methyltransf_23 PF13489.6 AMK75103.1 - 5e-22 78.5 0.0 7.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75103.1 - 3.9e-15 56.0 0.0 5.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75103.1 - 8.8e-15 55.1 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75103.1 - 3.1e-13 50.3 0.1 5.1e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75103.1 - 1.7e-12 47.9 0.0 3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AMK75103.1 - 9.3e-10 38.4 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 AMK75103.1 - 4.5e-06 25.8 0.0 7.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 AMK75103.1 - 0.00057 19.5 0.0 0.00096 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 AMK75103.1 - 0.00097 18.5 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 AMK75103.1 - 0.0044 17.1 0.0 0.0088 16.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 AMK75103.1 - 0.0056 16.0 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 AMK75103.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) CMAS PF02353.20 AMK75103.1 - 0.058 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 AMK75103.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 AMK75104.1 - 3.1e-11 44.2 0.0 5.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75104.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glycos_transf_1 PF00534.20 AMK75105.1 - 1.2e-30 106.3 0.0 2.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AMK75105.1 - 3.2e-27 95.4 0.0 5.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 AMK75105.1 - 1.6e-25 90.1 0.1 4.5e-25 88.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 AMK75105.1 - 2.3e-12 47.3 0.0 9.2e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_4 PF13439.6 AMK75105.1 - 3.1e-11 43.6 0.1 4.1e-06 26.9 0.0 3.2 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_tranf_2_2 PF10111.9 AMK75105.1 - 2.5e-08 33.7 0.0 2.5e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_1_2 PF13524.6 AMK75105.1 - 1.9e-06 28.1 0.1 4.4e-05 23.8 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK75105.1 - 0.0011 19.4 0.0 0.28 11.6 0.0 3.3 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_tranf_2_4 PF13704.6 AMK75105.1 - 0.052 14.1 0.3 0.22 12.0 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 SCAMP PF04144.13 AMK75105.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 SCAMP family LPG_synthase_TM PF03706.13 AMK75106.1 - 5.3e-37 128.0 37.6 6.1e-37 127.8 37.6 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region DUF2304 PF10066.9 AMK75108.1 - 2.2e-09 37.5 8.1 2.9e-09 37.1 8.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2304) TRP PF06011.12 AMK75108.1 - 1.9 7.1 10.1 2.4 6.8 10.1 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF1980 PF09323.10 AMK75108.1 - 2.6 7.9 5.2 14 5.5 5.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Glycos_transf_2 PF00535.26 AMK75109.1 - 3.4e-21 75.8 0.0 4.7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK75109.1 - 0.003 17.5 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PucR PF07905.11 AMK75109.1 - 0.0052 17.1 0.0 0.075 13.3 0.0 2.1 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family PGM_PMM_II PF02879.16 AMK75109.1 - 0.0096 16.5 0.1 1.4 9.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF442 PF04273.13 AMK75109.1 - 0.048 13.8 0.2 15 5.7 0.0 2.5 2 1 0 2 2 2 0 Putative phosphatase (DUF442) PrpR_N PF06506.11 AMK75109.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Hexapep PF00132.24 AMK75110.1 - 2.5e-10 39.6 11.2 1.2e-07 31.1 5.6 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AMK75110.1 - 2.1e-05 24.2 5.5 2.1e-05 24.2 5.5 2.6 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Acetyltransf_3 PF13302.7 AMK75111.1 - 7.2e-15 55.9 0.0 8.2e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AMK75111.1 - 5.2e-09 36.4 0.0 6.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK75111.1 - 7.1e-09 35.9 0.0 8.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AMK75111.1 - 4.1e-07 29.9 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AMK75111.1 - 2.4e-06 27.3 0.0 1.2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AMK75111.1 - 7.4e-06 25.9 0.0 9.7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AMK75111.1 - 3.1e-05 24.2 0.0 4.9e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK75111.1 - 0.0058 16.7 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 AMK75111.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ GNAT_acetyltran PF12746.7 AMK75111.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase DegT_DnrJ_EryC1 PF01041.17 AMK75112.1 - 1.1e-125 419.7 0.0 1.3e-125 419.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AMK75112.1 - 3.9e-09 36.1 0.0 7.4e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AMK75112.1 - 0.00019 20.1 0.0 0.00025 19.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FLgD_tudor PF13861.6 AMK75112.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 FlgD Tudor-like domain OKR_DC_1 PF01276.20 AMK75112.1 - 0.075 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Epimerase_2 PF02350.19 AMK75113.1 - 8.8e-87 291.2 0.0 1.1e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 AMK75113.1 - 0.033 14.6 0.1 0.18 12.2 0.0 2.2 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.20 AMK75113.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Peptidase_M15_3 PF08291.11 AMK75113.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase M15 Polysacc_synt_2 PF02719.15 AMK75114.1 - 4.7e-103 344.4 1.4 5.6e-103 344.1 1.4 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AMK75114.1 - 2.6e-24 86.0 0.0 3.9e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_syn_2C PF08485.10 AMK75114.1 - 1.8e-23 81.9 1.1 3.6e-23 81.0 1.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein C-terminal 3Beta_HSD PF01073.19 AMK75114.1 - 4.8e-16 58.6 2.0 5.7e-15 55.1 0.1 2.7 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AMK75114.1 - 9e-14 51.8 0.2 2e-13 50.7 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AMK75114.1 - 4.6e-12 46.0 0.0 2.5e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 AMK75114.1 - 2.4e-07 30.6 0.1 3.5e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 AMK75114.1 - 4.6e-06 25.9 0.0 2.3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 AMK75114.1 - 6.4e-06 26.4 0.1 2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 AMK75114.1 - 2.5e-05 23.6 0.6 0.00028 20.1 0.6 2.3 1 1 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.17 AMK75114.1 - 0.00029 21.4 0.6 0.0056 17.2 0.0 2.8 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 AMK75114.1 - 0.0015 18.5 0.0 0.0043 17.0 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 AMK75114.1 - 0.0021 18.0 0.0 0.0073 16.3 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.24 AMK75114.1 - 0.0049 17.3 0.0 0.15 12.5 0.0 2.6 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AMK75114.1 - 0.0074 16.3 0.1 0.026 14.6 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 AMK75115.1 - 2.5e-27 95.7 0.0 7e-27 94.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AMK75115.1 - 9.2e-15 54.7 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK75115.1 - 4.6e-07 29.6 0.0 7.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AMK75115.1 - 0.0039 17.1 0.0 0.0048 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AMK75115.1 - 0.008 16.1 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 AMK75115.1 - 0.042 13.0 0.0 0.83 8.8 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 AMK75115.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 AMK75115.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain dTDP_sugar_isom PF00908.17 AMK75116.1 - 7.4e-74 247.0 0.0 8.3e-74 246.9 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase NTP_transferase PF00483.23 AMK75117.1 - 2.3e-72 243.5 0.0 2.7e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AMK75117.1 - 2.6e-09 37.6 0.0 3.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AMK75117.1 - 0.00095 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RmlD_sub_bind PF04321.17 AMK75118.1 - 3.4e-110 367.7 0.0 4.2e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AMK75118.1 - 5.9e-15 55.4 0.0 1.7e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK75118.1 - 3e-10 40.0 0.0 7.8e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AMK75118.1 - 3.6e-07 29.6 0.0 5.4e-06 25.8 0.0 2.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AMK75118.1 - 6.6e-06 25.5 0.0 1.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AMK75119.1 - 4.8e-102 341.8 0.0 5.5e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AMK75119.1 - 3.6e-67 226.3 0.0 4.4e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AMK75119.1 - 3.3e-12 46.1 0.0 5.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AMK75119.1 - 5.1e-11 42.2 0.1 4.7e-10 39.1 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 AMK75119.1 - 1.2e-10 41.1 0.0 7.3e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 AMK75119.1 - 3.4e-09 36.1 0.0 5.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 AMK75119.1 - 1.3e-05 24.8 0.1 0.082 12.3 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase HATPase_c PF02518.26 AMK75120.1 - 0.00014 22.4 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AMK75120.1 - 0.0048 16.7 0.6 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK75120.1 - 0.03 14.3 0.1 0.056 13.4 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain NTP_transf_3 PF12804.7 AMK75120.1 - 0.1 13.0 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain TPR_2 PF07719.17 AMK75121.1 - 1.7e-20 71.4 13.1 3.1e-06 26.9 0.0 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 AMK75121.1 - 3.7e-19 69.0 17.1 0.00036 21.0 0.0 7.5 6 2 3 9 9 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75121.1 - 2.5e-18 65.2 8.8 0.0098 16.6 0.2 8.4 7 2 2 9 9 8 4 Tetratricopeptide repeat Response_reg PF00072.24 AMK75121.1 - 6.5e-18 64.9 0.0 2.2e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain TPR_1 PF00515.28 AMK75121.1 - 1.3e-16 59.6 11.7 9.3e-07 28.4 0.0 7.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75121.1 - 2.8e-15 56.4 11.7 0.0027 17.9 0.0 6.1 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75121.1 - 2.9e-14 53.4 2.9 0.13 12.9 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 AMK75121.1 - 3.3e-12 46.2 12.3 1.6 9.5 0.2 8.7 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 AMK75121.1 - 1.9e-11 43.2 15.5 0.18 12.1 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75121.1 - 7.9e-10 38.3 5.5 0.011 15.4 0.0 5.8 5 2 2 7 7 7 2 TPR repeat TPR_7 PF13176.6 AMK75121.1 - 2.9e-09 36.3 4.4 0.014 15.4 0.0 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AMK75121.1 - 2e-07 30.7 8.2 0.082 12.3 2.0 3.9 3 1 0 3 3 3 3 MalT-like TPR region PPR PF01535.20 AMK75121.1 - 3.5e-07 30.0 2.0 1.9 8.9 0.1 5.8 6 0 0 6 6 5 2 PPR repeat TPR_21 PF09976.9 AMK75121.1 - 1.3e-06 28.3 9.8 0.061 13.0 6.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 AMK75121.1 - 1.4e-06 28.5 7.8 0.92 9.8 0.0 4.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AMK75121.1 - 2.6e-06 27.1 13.7 0.00026 20.7 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 AMK75121.1 - 1.2e-05 24.2 2.2 0.0017 17.2 0.4 2.7 3 0 0 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 AMK75121.1 - 1.3e-05 25.3 0.0 5.9 7.8 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat BTAD PF03704.17 AMK75121.1 - 0.00031 21.2 4.5 0.004 17.6 0.1 4.1 3 2 2 5 5 5 1 Bacterial transcriptional activator domain RPN7 PF10602.9 AMK75121.1 - 0.00097 18.9 7.8 0.017 14.8 4.0 3.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 PPR_2 PF13041.6 AMK75121.1 - 0.0029 17.8 0.9 6.4 7.1 0.1 3.8 3 0 0 3 3 3 1 PPR repeat family TPR_9 PF13371.6 AMK75121.1 - 0.0034 17.5 0.9 17 5.7 0.0 4.3 2 1 3 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AMK75121.1 - 0.047 13.8 2.4 1.3 9.1 0.0 4.2 5 1 1 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat PPR_1 PF12854.7 AMK75121.1 - 0.07 12.8 1.4 9.6 6.0 0.1 4.4 5 0 0 5 5 5 0 PPR repeat Vps23_core PF09454.10 AMK75121.1 - 0.11 12.5 1.7 12 5.9 0.0 3.5 3 0 0 3 3 3 0 Vps23 core domain MIT PF04212.18 AMK75121.1 - 0.15 12.2 11.5 7.4 6.7 0.0 4.5 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 AMK75121.1 - 0.3 11.1 7.2 1.1 9.3 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat HSP90 PF00183.18 AMK75122.1 - 1.7e-145 485.9 8.6 7.1e-142 473.9 6.8 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 AMK75122.1 - 1.7e-13 50.6 0.4 5.2e-13 49.0 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AMK75122.1 - 4.2e-13 49.8 0.2 1.1e-12 48.4 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_40 PF14493.6 AMK75122.1 - 0.59 10.6 6.1 4.2 7.9 1.5 3.7 2 1 1 3 3 3 0 Helix-turn-helix domain PBP_like_2 PF12849.7 AMK75123.1 - 0.025 14.3 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 PBP superfamily domain EP400_N PF15790.5 AMK75124.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal GGDEF PF00990.21 AMK75125.1 - 1.9e-45 154.5 1.3 1.1e-44 152.0 0.7 2.1 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_8 PF13188.7 AMK75125.1 - 1.2e-05 25.1 0.4 0.0019 18.2 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK75125.1 - 0.00022 21.2 0.0 0.00082 19.4 0.0 2.0 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK75125.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AMK75125.1 - 0.0042 17.4 0.3 0.015 15.7 0.1 2.1 2 0 0 2 2 2 1 HAMP domain PEP-CTERM PF07589.11 AMK75126.1 - 0.0019 18.2 1.9 0.0019 18.2 1.9 1.9 2 0 0 2 2 2 1 PEP-CTERM motif DUF924 PF06041.11 AMK75127.1 - 2.8e-59 200.3 0.3 3.2e-59 200.1 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PAS_7 PF12860.7 AMK75128.1 - 0.023 14.8 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold LPAM_1 PF08139.12 AMK75128.1 - 0.23 12.0 1.0 0.6 10.7 1.0 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site NAD_kinase PF01513.21 AMK75130.1 - 6.9e-63 212.6 0.4 8.9e-63 212.2 0.4 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AMK75130.1 - 0.0045 16.6 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SMC_N PF02463.19 AMK75131.1 - 1.2e-17 64.1 0.0 5.5e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK75131.1 - 2.2e-12 47.9 8.2 1.2e-10 42.2 8.2 2.3 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK75131.1 - 0.00012 22.6 1.1 0.17 12.4 0.4 3.6 3 2 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 AMK75131.1 - 0.00015 21.7 0.0 0.03 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system PilJ PF13675.6 AMK75131.1 - 0.0081 16.2 6.0 0.84 9.7 0.9 2.8 2 0 0 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_29 PF13555.6 AMK75131.1 - 0.0083 15.9 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_TATA_bd PF12325.8 AMK75131.1 - 0.019 15.2 1.3 0.019 15.2 1.3 3.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding RsgA_GTPase PF03193.16 AMK75131.1 - 0.043 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 AMK75131.1 - 0.057 13.7 8.2 0.58 10.4 4.5 3.4 3 1 0 3 3 3 0 AAA domain GrpE PF01025.19 AMK75131.1 - 0.24 11.1 0.1 0.24 11.1 0.1 2.4 2 1 0 2 2 2 0 GrpE DUF3829 PF12889.7 AMK75131.1 - 0.27 10.7 3.3 0.74 9.2 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) PLU-1 PF08429.11 AMK75131.1 - 0.55 9.4 14.0 0.039 13.1 3.0 2.9 1 1 2 3 3 3 0 PLU-1-like protein RhoGEF PF00621.20 AMK75131.1 - 0.63 10.3 3.4 2 8.6 2.8 2.1 1 1 1 2 2 2 0 RhoGEF domain TBCA PF02970.16 AMK75131.1 - 4.3 7.7 7.2 52 4.3 0.1 3.9 4 1 0 4 4 4 0 Tubulin binding cofactor A EamA PF00892.20 AMK75132.1 - 8.3e-33 113.5 40.6 1.5e-17 64.0 13.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AMK75132.1 - 0.00077 18.9 13.5 0.0086 15.5 0.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 AMK75132.1 - 0.89 8.4 13.5 0.052 12.5 3.8 2.1 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DUF5337 PF17272.2 AMK75132.1 - 3.6 7.5 7.2 8.6 6.3 0.1 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5337) Phytase-like PF13449.6 AMK75133.1 - 6.5e-64 216.6 1.8 7.7e-64 216.4 1.8 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase PQQ PF01011.21 AMK75133.1 - 0.043 13.7 0.5 0.62 10.1 0.0 3.1 3 1 0 3 3 3 0 PQQ enzyme repeat VID27 PF08553.10 AMK75133.1 - 0.044 12.8 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain MCPsignal PF00015.21 AMK75134.1 - 4.8e-43 146.9 38.3 6.9e-43 146.4 18.2 3.4 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AMK75134.1 - 2.8e-10 40.4 0.1 2.8e-10 40.4 0.1 3.6 5 1 1 6 6 3 1 HAMP domain CheZ PF04344.13 AMK75134.1 - 0.00019 21.4 1.3 0.00019 21.4 1.3 2.6 2 1 0 2 2 2 1 Chemotaxis phosphatase, CheZ HsbA PF12296.8 AMK75134.1 - 0.0022 18.4 5.3 0.0022 18.4 5.3 3.7 1 1 1 3 3 3 1 Hydrophobic surface binding protein A Fib_alpha PF08702.10 AMK75134.1 - 0.017 15.3 15.8 0.98 9.6 6.8 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 AMK75134.1 - 0.021 12.4 27.1 0.027 12.0 27.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hydrolase_6 PF13344.6 AMK75134.1 - 0.027 14.6 0.6 0.12 12.5 0.6 2.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1664 PF07889.12 AMK75134.1 - 0.16 12.0 19.3 0.25 11.4 0.7 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Mce4_CUP1 PF11887.8 AMK75134.1 - 0.25 10.8 16.2 0.11 11.9 2.5 2.4 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Tht1 PF04163.12 AMK75134.1 - 0.28 9.9 4.2 0.44 9.2 4.2 1.3 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein MCU PF04678.13 AMK75134.1 - 0.48 10.5 10.1 1.8 8.6 2.8 2.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RIFIN PF02009.16 AMK75134.1 - 0.53 10.1 14.1 2.6 7.9 6.8 2.2 2 0 0 2 2 2 0 Rifin Mod_r PF07200.13 AMK75134.1 - 0.89 9.6 17.5 1.1 9.3 1.7 3.6 2 2 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4795 PF16043.5 AMK75134.1 - 1.3 8.6 13.3 3.2 7.3 4.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4200 PF13863.6 AMK75134.1 - 1.6 9.1 14.8 2 8.8 1.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Vps54_N PF10475.9 AMK75134.1 - 1.8 7.7 6.8 1.1 8.5 0.3 2.4 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex FliD_N PF02465.18 AMK75134.1 - 2.6 8.8 19.7 8.2 7.2 5.9 3.0 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Atg14 PF10186.9 AMK75134.1 - 3 6.8 13.9 0.57 9.2 6.6 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 AMK75134.1 - 3.3 6.9 10.6 5.1 6.2 0.5 2.5 2 0 0 2 2 2 0 TMPIT-like protein GCN5L1 PF06320.13 AMK75134.1 - 3.4 7.9 16.8 0.97 9.6 5.9 3.1 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) BLOC1_2 PF10046.9 AMK75134.1 - 5.1 7.5 19.4 23 5.4 0.1 4.5 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YkyA PF10368.9 AMK75134.1 - 5.6 6.6 16.8 14 5.3 7.7 3.0 2 2 0 2 2 2 0 Putative cell-wall binding lipoprotein Goodbye PF17109.5 AMK75134.1 - 6.3 7.3 12.6 2.5 8.6 1.2 3.1 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain Peptidase_C98 PF15499.6 AMK75134.1 - 6.7 6.1 6.3 15 5.0 1.8 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4559 PF15112.6 AMK75134.1 - 6.9 6.3 11.1 3 7.5 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF2935 PF11155.8 AMK75134.1 - 7.1 7.0 6.2 5.3 7.4 0.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) CREPT PF16566.5 AMK75134.1 - 7.7 6.7 14.7 2 8.6 4.8 3.0 3 1 0 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2339 PF10101.9 AMK75135.1 - 5.8e-94 316.0 93.8 8.4e-94 315.5 93.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF3999 PF13163.6 AMK75136.1 - 9.8e-12 44.8 3.3 1.7e-07 30.8 0.4 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3999) ArnB_C PF18677.1 AMK75136.1 - 0.039 14.1 0.2 0.071 13.2 0.2 1.4 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Na_H_Exchanger PF00999.21 AMK75137.1 - 5e-31 107.8 32.4 6.3e-30 104.2 32.4 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AMK75137.1 - 1.5e-15 57.5 0.0 2.4e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain PhyH PF05721.13 AMK75138.1 - 1e-13 52.0 0.0 1.4e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_5 PF00266.19 AMK75139.1 - 1.6e-54 185.3 0.0 2e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AMK75139.1 - 5.3e-06 25.2 0.0 6.6e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GPW_gp25 PF04965.14 AMK75139.1 - 0.059 13.1 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Gene 25-like lysozyme DUF4096 PF13340.6 AMK75140.1 - 6.7e-24 83.9 4.8 1.4e-23 82.9 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK75141.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK75141.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK75141.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK75141.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Potass_KdpF PF09604.10 AMK75142.1 - 6.7e-07 29.1 6.3 6.7e-07 29.1 6.3 1.5 1 1 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) KdpA PF03814.15 AMK75143.1 - 6.9e-242 803.5 26.6 8.8e-242 803.1 26.6 1.1 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit DUF1686 PF07937.11 AMK75143.1 - 0.021 14.7 1.0 0.021 14.7 1.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1686) Hydrolase PF00702.26 AMK75144.1 - 4.7e-32 112.0 4.4 4.7e-32 112.0 4.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 AMK75144.1 - 1.2e-31 109.7 1.4 1.2e-31 109.7 1.4 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 AMK75144.1 - 5e-05 23.8 0.7 0.00027 21.4 0.1 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK75144.1 - 0.00047 20.0 1.5 0.00062 19.6 0.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase KdpC PF02669.15 AMK75145.1 - 2.9e-74 248.9 0.0 3.2e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain KdpD PF02702.17 AMK75146.1 - 1.7e-96 321.7 0.1 3.3e-96 320.7 0.1 1.5 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 AMK75146.1 - 1.4e-27 95.6 12.8 3.2e-27 94.4 12.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AMK75146.1 - 2.4e-24 86.0 0.0 7.6e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK75146.1 - 4.4e-15 55.5 3.4 6.6e-15 54.9 1.5 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 AMK75146.1 - 1.8e-10 41.5 5.0 2.5e-10 41.0 0.2 3.1 3 1 0 3 3 3 1 Universal stress protein family GAF_3 PF13492.6 AMK75146.1 - 2.6e-08 34.3 0.0 8.1e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AMK75146.1 - 0.017 15.7 0.1 0.11 13.1 0.0 2.4 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.6 AMK75146.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MASE1 PF05231.14 AMK75146.1 - 0.071 12.2 8.7 0.02 14.0 5.7 1.5 2 0 0 2 2 2 0 MASE1 MerE PF05052.12 AMK75146.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 MerE protein Response_reg PF00072.24 AMK75147.1 - 2.8e-27 95.1 0.0 4.2e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK75147.1 - 1.4e-22 79.6 0.0 2.6e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GGDEF PF00990.21 AMK75148.1 - 1.7e-46 157.9 0.0 2.5e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain FeS_assembly_P PF01883.19 AMK75149.1 - 1.9e-19 69.6 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein YmaF PF12788.7 AMK75149.1 - 0.061 13.9 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 YmaF family adh_short PF00106.25 AMK75150.1 - 1.3e-34 119.4 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AMK75150.1 - 6.5e-34 117.5 0.0 1.6e-33 116.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AMK75150.1 - 5.3e-10 39.5 0.2 7.1e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AMK75150.1 - 7e-06 25.6 0.0 9.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 AMK75150.1 - 0.07 12.3 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 AMK75150.1 - 0.099 12.1 1.1 0.29 10.6 0.4 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 AMK75150.1 - 0.18 11.7 0.3 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HAD_2 PF13419.6 AMK75151.1 - 2.5e-37 128.7 0.0 2.9e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK75151.1 - 8.2e-18 65.5 0.2 3.5e-16 60.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK75151.1 - 1.5e-10 41.8 0.0 2.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AMK75151.1 - 1.4e-09 37.8 0.0 2.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AMK75151.1 - 0.13 12.4 0.0 1.2 9.2 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 AMK75152.1 - 1.4e-25 90.0 0.0 3.1e-25 88.9 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75152.1 - 2.4e-20 73.0 0.0 5.4e-20 71.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75152.1 - 1.2e-17 64.4 0.1 2.7e-17 63.2 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75152.1 - 7.5e-15 55.5 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75152.1 - 1.8e-13 50.6 0.0 3.1e-13 49.8 0.0 1.4 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK75152.1 - 2e-08 33.9 0.0 2.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 AMK75152.1 - 6.1e-08 32.3 0.0 7.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 AMK75152.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 AMK75152.1 - 1.3e-05 24.9 0.0 1.8e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 AMK75152.1 - 2.5e-05 23.8 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 AMK75152.1 - 0.00018 21.2 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 AMK75152.1 - 0.0006 19.5 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AMK75152.1 - 0.0024 17.5 0.1 0.0045 16.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 AMK75152.1 - 0.0028 17.7 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 AMK75152.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 AMK75152.1 - 0.061 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 AMK75152.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF1574 PF07611.11 AMK75153.1 - 1.5e-06 27.8 0.1 2.2e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1574) MBOAT PF03062.19 AMK75154.1 - 3e-30 105.8 19.6 6.7e-30 104.6 19.1 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AMK75154.1 - 6.7e-06 26.3 1.7 2.5e-05 24.5 1.7 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Amidohydro_1 PF01979.20 AMK75155.1 - 3.7e-71 240.2 1.7 4.4e-71 240.0 1.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AMK75155.1 - 1.3e-18 67.7 4.5 6e-18 65.6 0.5 2.2 2 0 0 2 2 2 2 Amidohydrolase family PNPase_C PF12111.8 AMK75155.1 - 0.16 11.4 0.1 0.37 10.3 0.1 1.5 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Response_reg PF00072.24 AMK75156.1 - 1e-24 86.9 0.1 3.6e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HD PF01966.22 AMK75156.1 - 8.6e-19 68.0 0.8 1.5e-18 67.1 0.8 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AMK75156.1 - 1e-17 64.1 0.1 2.1e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 HD domain PAS_3 PF08447.12 AMK75157.1 - 2e-62 207.5 2.1 1.6e-21 76.4 0.2 6.2 6 0 0 6 6 6 5 PAS fold PAS_9 PF13426.7 AMK75157.1 - 2.2e-58 195.0 0.3 1.7e-12 47.5 0.2 6.6 6 0 0 6 6 6 5 PAS domain PAS PF00989.25 AMK75157.1 - 1.8e-45 153.5 3.2 3.3e-11 43.2 0.0 6.7 6 0 0 6 6 6 6 PAS fold PAS_4 PF08448.10 AMK75157.1 - 1.7e-43 147.3 2.3 2.4e-15 56.7 0.0 6.7 6 0 0 6 6 6 6 PAS fold PAS_8 PF13188.7 AMK75157.1 - 1.7e-37 126.8 1.7 5.3e-10 39.1 0.1 6.9 6 0 0 6 6 6 5 PAS domain MASE1 PF05231.14 AMK75157.1 - 7.7e-31 107.3 28.5 1.1e-30 106.9 28.5 1.2 1 0 0 1 1 1 1 MASE1 Response_reg PF00072.24 AMK75157.1 - 4.7e-29 100.8 1.3 2.6e-28 98.4 0.3 2.9 3 0 0 3 3 3 1 Response regulator receiver domain HATPase_c PF02518.26 AMK75157.1 - 9.1e-26 90.6 0.1 2.2e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK75157.1 - 5.3e-18 64.8 0.6 5.3e-18 64.8 0.6 3.8 5 0 0 5 5 4 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AMK75157.1 - 1.1e-12 48.0 5.2 6.3e-12 45.6 5.2 2.4 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 AMK75157.1 - 2.5e-06 27.7 1.8 0.0075 16.4 0.0 4.8 4 1 0 4 4 4 1 PAS fold PAS_11 PF14598.6 AMK75157.1 - 3.7e-06 27.0 1.2 0.0063 16.6 0.0 3.8 3 0 0 3 3 3 1 PAS domain MEKHLA PF08670.11 AMK75157.1 - 0.055 13.4 1.0 14 5.6 0.0 3.7 4 0 0 4 4 4 0 MEKHLA domain D5_N PF08706.11 AMK75157.1 - 0.066 13.5 0.1 0.066 13.5 0.1 3.5 4 0 0 4 4 4 0 D5 N terminal like DUF4027 PF13219.6 AMK75157.1 - 1.8 8.5 3.9 4.5 7.2 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) IF-2B PF01008.17 AMK75158.1 - 3.4e-77 259.4 0.0 4.1e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family EI24 PF07264.11 AMK75159.1 - 3.7e-31 108.7 23.4 4.7e-31 108.4 23.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LETM1 PF07766.13 AMK75159.1 - 0.17 11.2 0.9 0.4 10.0 0.9 1.6 2 0 0 2 2 2 0 LETM1-like protein DUF1289 PF06945.13 AMK75160.1 - 3.8e-07 29.8 1.9 5.7e-07 29.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) DUF1258 PF06869.12 AMK75160.1 - 0.0043 16.6 0.1 0.0051 16.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Ole-e-6 PF09253.10 AMK75160.1 - 0.18 11.7 4.6 0.37 10.8 4.6 1.5 1 0 0 1 1 1 0 Pollen allergen ole e 6 PEP-CTERM PF07589.11 AMK75161.1 - 0.01 15.9 0.5 0.01 15.9 0.5 2.6 3 0 0 3 3 3 0 PEP-CTERM motif VPDSG-CTERM PF18205.1 AMK75161.1 - 0.34 10.8 0.2 0.34 10.8 0.2 2.6 2 0 0 2 2 2 0 VPDSG-CTERM motif HTH_18 PF12833.7 AMK75163.1 - 7.8e-18 64.5 0.1 1.8e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AMK75163.1 - 1.1e-10 41.3 0.1 1.5e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Sigma70_r3 PF04539.16 AMK75163.1 - 0.013 15.6 0.0 0.055 13.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 3 TPR_8 PF13181.6 AMK75165.1 - 0.00096 19.2 1.1 0.0019 18.3 0.3 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75165.1 - 0.024 14.7 0.4 0.086 13.0 0.1 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75165.1 - 0.049 13.9 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75165.1 - 0.096 12.4 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 TPR repeat HemY_N PF07219.13 AMK75165.1 - 0.16 12.2 1.4 2.2 8.5 0.2 2.2 1 1 1 2 2 2 0 HemY protein N-terminus SMBP PF16785.5 AMK75165.1 - 0.68 10.2 7.1 2.8 8.2 7.1 2.0 1 1 0 1 1 1 0 Small metal-binding protein LysR_substrate PF03466.20 AMK75166.1 - 5.1e-43 146.9 0.0 6.7e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK75166.1 - 2.8e-14 52.8 0.2 5e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family zf-RING_11 PF17123.5 AMK75166.1 - 0.002 17.8 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger HTH_30 PF13556.6 AMK75166.1 - 0.019 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-RING_2 PF13639.6 AMK75166.1 - 0.053 13.9 0.2 0.096 13.0 0.2 1.3 1 0 0 1 1 1 0 Ring finger domain MarR_2 PF12802.7 AMK75166.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 MarR family PAS PF00989.25 AMK75167.1 - 1.4e-38 131.3 1.1 5.2e-16 58.7 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 AMK75167.1 - 4.5e-33 113.6 0.0 9.4e-12 45.1 0.0 3.5 3 0 0 3 3 3 3 PAS domain HATPase_c PF02518.26 AMK75167.1 - 1.1e-29 103.2 0.1 6.3e-29 100.7 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK75167.1 - 3e-24 85.3 2.7 5.4e-24 84.5 0.1 2.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 AMK75167.1 - 3.8e-22 78.6 0.6 4.3e-07 30.2 0.1 3.7 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AMK75167.1 - 1.5e-21 75.9 0.3 1.5e-05 24.9 0.0 3.9 3 0 0 3 3 3 3 PAS domain HisKA PF00512.25 AMK75167.1 - 1.2e-16 60.5 0.1 1.2e-16 60.5 0.1 4.8 5 0 0 5 5 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK75167.1 - 4.7e-11 42.9 0.0 2e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 HAMP domain Hpt PF01627.23 AMK75167.1 - 2.1e-07 31.1 4.5 2.1e-07 31.1 4.5 2.6 2 0 0 2 2 2 1 Hpt domain HATPase_c_3 PF13589.6 AMK75167.1 - 1.2e-05 25.2 0.0 4.2e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 AMK75167.1 - 0.00046 20.3 0.1 0.87 9.8 0.0 3.1 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AMK75167.1 - 0.00095 19.4 0.0 0.78 10.1 0.0 2.8 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AMK75167.1 - 0.031 14.2 1.9 0.16 12.0 0.0 2.9 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain Halo_GVPC PF05465.13 AMK75167.1 - 0.035 14.4 1.3 0.18 12.1 0.3 2.7 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Inhibitor_I9 PF05922.16 AMK75167.1 - 0.042 14.5 2.0 0.33 11.6 0.1 2.9 3 0 0 3 3 2 0 Peptidase inhibitor I9 GLYCAM-1 PF05242.11 AMK75167.1 - 0.15 12.2 0.8 25 5.0 0.0 3.5 3 0 0 3 3 3 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Response_reg PF00072.24 AMK75168.1 - 1.2e-24 86.6 1.7 1.3e-24 86.5 0.3 1.8 2 0 0 2 2 2 1 Response regulator receiver domain FAM167 PF11652.8 AMK75168.1 - 0.75 10.3 5.3 1 9.9 0.7 2.9 3 0 0 3 3 3 0 FAM167 Amidase_2 PF01510.25 AMK75169.1 - 1.4e-34 119.3 0.0 5.8e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 N-acetylmuramoyl-L-alanine amidase SH3_3 PF08239.11 AMK75169.1 - 0.00041 20.6 0.1 0.00087 19.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain LPP PF04728.13 AMK75170.1 - 0.011 16.1 0.3 0.039 14.3 0.3 2.0 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF3899 PF13038.6 AMK75170.1 - 1 9.9 2.6 2.7 8.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) AstE_AspA PF04952.14 AMK75171.1 - 3.7e-09 36.1 0.0 4.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PIR PF00399.19 AMK75171.1 - 2.1 8.0 4.4 0.41 10.3 0.6 1.9 2 0 0 2 2 2 0 Yeast PIR protein repeat HEPN PF05168.14 AMK75172.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 HEPN domain Imm51 PF15595.6 AMK75173.1 - 2.2e-20 72.5 0.3 2.6e-20 72.3 0.3 1.1 1 0 0 1 1 1 1 Immunity protein 51 GCS2 PF04107.13 AMK75174.1 - 5.6e-07 29.2 0.2 3.3e-05 23.4 0.2 2.3 1 1 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) DUF4186 PF13811.6 AMK75175.1 - 6.2e-51 171.0 0.1 6.9e-51 170.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4186) DHO_dh PF01180.21 AMK75176.1 - 3.1e-10 39.8 0.0 8e-10 38.4 0.0 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 AMK75176.1 - 1.7e-05 24.1 0.1 0.00038 19.6 0.0 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 AMK75176.1 - 0.0019 17.4 0.1 0.0033 16.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 AMK75176.1 - 0.0046 16.0 0.0 0.046 12.7 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Dus PF01207.17 AMK75176.1 - 0.035 13.2 0.0 0.33 10.0 0.0 2.5 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) BtpA PF03437.15 AMK75176.1 - 0.053 13.0 0.0 10 5.5 0.0 3.1 3 0 0 3 3 3 0 BtpA family PEP_mutase PF13714.6 AMK75176.1 - 0.074 12.5 0.0 11 5.4 0.0 3.1 2 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase POR_N PF01855.19 AMK75177.1 - 3.2e-77 259.4 0.1 5.5e-77 258.6 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 AMK75177.1 - 1.6e-25 90.2 0.1 3.1e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 AMK75177.1 - 5.7e-22 77.3 0.0 1.3e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function PFOR_II PF17147.4 AMK75177.1 - 1.3e-15 57.5 0.0 3.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_16 PF13484.6 AMK75177.1 - 3.5e-10 40.7 4.3 8.6e-10 39.4 4.3 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.21 AMK75177.1 - 4.3e-10 39.6 0.0 1.3e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.27 AMK75177.1 - 7.4e-09 35.1 21.2 6.8e-05 22.5 4.5 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AMK75177.1 - 2.9e-08 33.8 5.8 7.5e-08 32.4 4.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK75177.1 - 3.1e-08 34.1 5.6 3.1e-08 34.1 5.6 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK75177.1 - 6e-07 29.3 19.0 0.00012 22.0 2.5 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 AMK75177.1 - 1.3e-06 28.9 4.5 0.022 15.3 0.3 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK75177.1 - 4.6e-06 26.7 10.3 4.6e-06 26.7 10.3 2.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK75177.1 - 8.7e-06 26.1 4.7 0.017 15.5 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK75177.1 - 2.2e-05 24.3 18.1 0.015 15.4 3.0 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AMK75177.1 - 7.7e-05 22.7 14.9 0.0004 20.4 12.6 2.6 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK75177.1 - 0.00041 20.6 15.1 0.0019 18.6 1.0 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 AMK75177.1 - 0.017 16.0 2.1 0.017 16.0 2.1 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 AMK75177.1 - 0.068 14.0 7.7 4.8 8.1 0.9 3.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AMK75177.1 - 0.65 10.8 7.3 2 9.2 0.6 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 AMK75177.1 - 0.93 10.1 11.6 1.6 9.4 1.2 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AMK75177.1 - 3.9 7.7 10.8 4 7.7 6.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain YkuD PF03734.14 AMK75180.1 - 1.3e-26 93.7 0.0 2.3e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 AMK75180.1 - 1e-09 38.4 1.2 1e-09 38.4 1.2 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 AMK75180.1 - 0.043 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain DUF2905 PF11146.8 AMK75182.1 - 1.7e-19 69.7 6.0 1.9e-19 69.6 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2905) Phage_holin_2_1 PF04971.12 AMK75182.1 - 1.7 8.7 4.2 2.9 8.0 0.7 2.1 1 1 1 2 2 2 0 Bacteriophage P21 holin S UPF0227 PF05728.12 AMK75183.1 - 1.1e-05 25.5 0.0 5.6e-05 23.2 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 AMK75183.1 - 0.00029 20.2 0.0 0.011 15.0 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AMK75183.1 - 0.00033 21.3 0.2 0.0004 21.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 AMK75183.1 - 0.0059 16.5 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AMK75183.1 - 0.016 14.7 0.1 3.9 6.9 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 AMK75183.1 - 0.024 14.3 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2235 PF09994.9 AMK75183.1 - 0.22 10.8 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Rubredoxin PF00301.20 AMK75184.1 - 1.8e-23 82.3 6.0 2.1e-23 82.1 6.0 1.0 1 0 0 1 1 1 1 Rubredoxin Zn-ribbon_8 PF09723.10 AMK75184.1 - 0.028 14.6 6.0 0.19 11.8 6.0 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 AMK75184.1 - 0.029 14.1 0.2 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein C1_2 PF03107.16 AMK75184.1 - 0.076 13.3 4.1 1.9 8.9 1.8 2.1 2 0 0 2 2 2 0 C1 domain zf-RanBP PF00641.18 AMK75184.1 - 0.1 12.0 0.5 0.1 12.0 0.5 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HypA PF01155.19 AMK75184.1 - 0.17 11.9 0.1 0.21 11.6 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RbpA PF13397.6 AMK75184.1 - 0.22 12.2 0.8 0.3 11.7 0.8 1.5 1 1 0 1 1 1 0 RNA polymerase-binding protein PHD_4 PF16866.5 AMK75184.1 - 0.66 10.1 5.3 1.1 9.3 5.3 1.5 1 1 0 1 1 1 0 PHD-finger Rick_17kDa_Anti PF05433.15 AMK75185.1 - 8.8e-05 22.3 12.3 0.00016 21.5 12.3 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AMK75185.1 - 0.0014 18.3 8.0 0.0024 17.5 8.0 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AMK75185.1 - 0.037 14.0 12.4 0.037 14.0 12.4 1.5 2 0 0 2 2 2 0 Glycine zipper CAP_N PF01213.19 AMK75185.1 - 0.21 11.1 0.2 0.2 11.1 0.2 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Acyl_transf_3 PF01757.22 AMK75187.1 - 1.7e-25 89.8 35.0 1.7e-25 89.8 35.0 2.0 1 1 1 2 2 2 1 Acyltransferase family Gram_pos_anchor PF00746.21 AMK75187.1 - 0.18 11.8 1.8 2.7 8.0 0.2 3.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Band_7 PF01145.25 AMK75188.1 - 9.8e-27 94.1 0.2 1.7e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Cep57_CLD_2 PF14197.6 AMK75188.1 - 0.051 13.7 0.5 0.095 12.8 0.5 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Band_7_1 PF13421.6 AMK75188.1 - 0.07 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Selenoprotein_S PF06936.11 AMK75188.1 - 0.074 12.9 0.6 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) Band_7 PF01145.25 AMK75189.1 - 3.1e-24 86.0 0.7 5.2e-24 85.2 0.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family EAL PF00563.20 AMK75190.1 - 1.3e-72 244.2 0.0 2.5e-72 243.2 0.0 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK75190.1 - 1.7e-51 174.2 0.1 4.5e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 AMK75190.1 - 9.9e-40 136.0 0.0 1.4e-19 70.7 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 AMK75190.1 - 5.1e-21 75.7 0.0 2.2e-12 47.7 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 AMK75190.1 - 0.00014 22.2 0.0 0.11 12.8 0.0 3.0 2 1 0 2 2 2 2 GAF domain GGDEF_2 PF17853.1 AMK75190.1 - 0.028 14.7 0.3 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 GGDEF-like domain AhpC-TSA PF00578.21 AMK75191.1 - 1.3e-35 122.0 0.0 1.7e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK75191.1 - 1.6e-21 76.5 0.0 2.1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AMK75191.1 - 0.0051 16.9 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AMK75191.1 - 0.07 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) CorA PF01544.18 AMK75192.1 - 7.8e-61 205.9 0.0 9e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein XG_FTase PF03254.13 AMK75193.1 - 0.18 10.4 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase E1-E2_ATPase PF00122.20 AMK75194.1 - 3.2e-47 160.4 3.3 4e-47 160.1 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AMK75194.1 - 1.5e-45 155.1 2.6 1.5e-45 155.1 2.6 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AMK75194.1 - 1.1e-22 81.3 0.2 3.8e-22 79.6 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AMK75194.1 - 1.3e-14 53.6 0.2 3.4e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AMK75194.1 - 1.2e-13 50.9 0.0 3.9e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AMK75194.1 - 6.9e-08 32.5 2.8 7.7e-06 25.8 2.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK75194.1 - 0.0033 17.9 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Flagellin_N PF00669.20 AMK75195.1 - 7.4e-31 107.1 13.4 7.4e-31 107.1 13.4 2.3 2 0 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AMK75195.1 - 3e-09 37.1 7.0 3e-09 37.1 7.0 3.1 3 1 0 3 3 3 1 Bacterial flagellin C-terminal helical region DUF1664 PF07889.12 AMK75195.1 - 0.01 15.9 0.8 0.22 11.5 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_holin_7_1 PF16081.5 AMK75195.1 - 0.033 14.4 10.6 0.055 13.6 4.3 2.4 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family CABS1 PF15367.6 AMK75195.1 - 0.04 13.0 0.8 0.047 12.8 0.8 1.3 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 WXG100 PF06013.12 AMK75195.1 - 0.052 13.8 5.2 0.48 10.7 0.9 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Snapin_Pallidin PF14712.6 AMK75195.1 - 0.074 13.5 5.1 0.36 11.3 0.1 3.3 3 1 1 4 4 3 0 Snapin/Pallidin Mor PF08765.11 AMK75195.1 - 0.083 12.9 0.8 0.3 11.1 0.1 2.2 2 1 0 2 2 2 0 Mor transcription activator family YjfB_motility PF14070.6 AMK75195.1 - 0.11 12.7 0.8 0.11 12.7 0.8 2.6 3 0 0 3 3 3 0 Putative motility protein DUF948 PF06103.11 AMK75195.1 - 0.29 11.4 3.5 1.9 8.8 0.8 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 AMK75195.1 - 0.55 10.7 6.4 1.9 9.0 2.0 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Med10 PF09748.9 AMK75195.1 - 0.72 9.8 3.5 12 5.9 0.5 2.7 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex Laminin_II PF06009.12 AMK75195.1 - 0.93 9.5 8.9 3.9 7.5 3.4 2.7 2 1 0 2 2 2 0 Laminin Domain II Uso1_p115_C PF04871.13 AMK75195.1 - 1.2 9.5 5.0 3 8.2 5.0 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4446 PF14584.6 AMK75196.1 - 0.021 14.8 2.0 0.028 14.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Not3 PF04065.15 AMK75196.1 - 0.031 13.7 2.1 0.037 13.5 2.1 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Spore_III_AF PF09581.10 AMK75196.1 - 0.13 12.3 3.4 0.15 12.1 3.4 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Spc24 PF08286.11 AMK75196.1 - 0.2 11.9 5.6 0.31 11.3 5.6 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF948 PF06103.11 AMK75196.1 - 0.28 11.5 3.6 0.41 10.9 3.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) T2SSM PF04612.12 AMK75196.1 - 0.52 10.4 11.9 0.74 9.9 11.9 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Alanine_zipper PF11839.8 AMK75196.1 - 4.8 7.6 30.9 33 5.0 5.9 2.9 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein P22_portal PF16510.5 AMK75196.1 - 8.4 4.8 12.6 9.3 4.7 12.6 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein KdgT PF03812.13 AMK75198.1 - 0.0095 15.3 2.7 0.0097 15.3 2.7 1.0 1 0 0 1 1 1 1 2-keto-3-deoxygluconate permease DrsE PF02635.15 AMK75199.1 - 0.00018 21.9 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 DsrE/DsrF-like family CN_hydrolase PF00795.22 AMK75200.1 - 2.1e-55 187.9 0.0 2.5e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Radical_SAM PF04055.21 AMK75201.1 - 6.9e-14 52.6 0.0 1.1e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AMK75202.1 - 5.9e-07 29.7 0.0 8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AMK75202.1 - 5.6e-05 23.1 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AMK75202.1 - 5.6e-05 23.5 0.0 9.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 AMK75202.1 - 0.0014 19.3 0.0 0.051 14.3 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain AIRS PF00586.24 AMK75203.1 - 1e-18 67.7 0.9 2.1e-18 66.8 0.7 1.6 1 1 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AMK75203.1 - 3.1e-10 40.4 0.0 5.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Glycos_transf_1 PF00534.20 AMK75204.1 - 6.6e-22 77.8 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK75204.1 - 2.3e-17 63.5 0.1 3.5e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK75204.1 - 2.1e-16 60.8 1.7 5.5e-16 59.4 0.5 2.2 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AMK75204.1 - 2.6e-15 57.0 0.0 4.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AMK75204.1 - 0.00073 19.6 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Pyr_redox_3 PF13738.6 AMK75206.1 - 3.3e-28 98.8 0.0 1.7e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AMK75206.1 - 1.1e-13 51.1 0.0 1.6e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 AMK75206.1 - 9.8e-13 47.9 0.1 2.1e-10 40.3 0.0 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AMK75206.1 - 2e-07 30.1 0.1 0.015 14.0 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 AMK75206.1 - 2.6e-06 27.3 1.7 0.00026 20.7 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase FMO-like PF00743.19 AMK75206.1 - 1.1e-05 24.1 0.1 8.9e-05 21.1 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 AMK75206.1 - 1.3e-05 24.6 0.0 0.00043 19.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 AMK75206.1 - 8.6e-05 21.8 0.4 0.0021 17.2 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 AMK75206.1 - 0.00012 22.2 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AMK75206.1 - 0.00033 20.7 0.3 1.1 9.2 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 AMK75206.1 - 0.00036 19.9 0.1 0.0062 15.8 0.0 2.2 1 1 1 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 AMK75206.1 - 0.01 14.9 0.0 0.52 9.3 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 AMK75206.1 - 0.016 15.7 0.1 7.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 AMK75206.1 - 0.1 12.9 0.9 7.2 6.9 0.2 2.8 3 0 0 3 3 3 0 TrkA-N domain GIDA PF01134.22 AMK75206.1 - 0.2 10.7 0.1 0.68 8.9 0.0 1.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Aminotran_1_2 PF00155.21 AMK75207.1 - 2.2e-30 106.1 0.0 2.7e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 AMK75207.1 - 7.2e-16 57.6 0.1 2.6e-15 55.8 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 AMK75207.1 - 0.00071 18.5 0.0 0.0015 17.4 0.0 1.5 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase HTH_24 PF13412.6 AMK75207.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Aminotran_5 PF00266.19 AMK75207.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V PI-PLC-X PF00388.19 AMK75207.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain ABC_tran PF00005.27 AMK75208.1 - 4.5e-05 24.0 0.1 7.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK75208.1 - 0.041 13.7 0.1 0.059 13.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MlaA PF04333.13 AMK75209.1 - 3.8e-69 232.3 0.2 5.1e-69 231.9 0.2 1.2 1 0 0 1 1 1 1 MlaA lipoprotein T2SSE PF00437.20 AMK75210.1 - 2e-74 250.1 0.4 2.9e-74 249.6 0.4 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AMK75210.1 - 1.1e-14 54.7 0.0 2.5e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_16 PF13191.6 AMK75210.1 - 8.3e-05 23.0 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AMK75210.1 - 0.00035 20.9 0.0 0.0019 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 AMK75210.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AMK75210.1 - 0.0019 18.2 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AMK75210.1 - 0.0025 17.8 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AMK75210.1 - 0.0027 18.2 0.1 0.0081 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 AMK75210.1 - 0.0045 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 AMK75210.1 - 0.0065 16.2 0.6 0.014 15.1 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 AMK75210.1 - 0.0072 16.3 0.2 0.17 11.8 0.2 2.4 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 AMK75210.1 - 0.0096 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 AMK75210.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK75210.1 - 0.023 15.0 0.8 0.048 14.0 0.8 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AMK75210.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 AMK75210.1 - 0.039 13.5 0.0 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AMK75210.1 - 0.04 14.5 0.2 0.35 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 AMK75210.1 - 0.071 11.1 0.0 0.1 10.6 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Microtub_bd PF16796.5 AMK75210.1 - 0.074 13.0 0.1 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Microtubule binding AAA PF00004.29 AMK75210.1 - 0.089 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AMK75210.1 - 0.091 12.9 0.4 0.24 11.6 0.2 1.9 2 1 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 AMK75210.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF853 PF05872.12 AMK75210.1 - 0.13 10.8 0.6 0.27 9.8 0.2 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) UvrD-helicase PF00580.21 AMK75210.1 - 0.76 9.2 2.6 0.59 9.6 0.1 2.0 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Transcrip_reg PF01709.20 AMK75211.1 - 6.1e-71 238.6 0.0 6.7e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator EAL PF00563.20 AMK75212.1 - 4.1e-76 255.6 1.4 7.1e-76 254.9 0.4 2.0 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK75212.1 - 8.2e-48 162.2 0.0 1.6e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK75212.1 - 5.9e-26 90.7 0.0 5.3e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK75212.1 - 4.2e-23 81.5 0.0 3.8e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AMK75212.1 - 1.5e-20 73.5 0.0 1e-10 41.9 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AMK75212.1 - 4.4e-11 42.5 0.1 3e-05 23.9 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 AMK75212.1 - 1.4e-06 28.5 0.0 0.00043 20.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_10 PF13596.6 AMK75212.1 - 0.0012 19.4 0.0 0.0045 17.6 0.0 2.0 1 0 0 1 1 1 1 PAS domain CCP_MauG PF03150.14 AMK75213.1 - 0.028 15.1 0.0 0.037 14.7 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Metallophos PF00149.28 AMK75214.1 - 2.9e-12 47.5 1.5 4e-12 47.1 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TAT_signal PF10518.9 AMK75214.1 - 4.6e-05 23.1 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Metallophos_2 PF12850.7 AMK75214.1 - 0.00031 21.0 0.0 0.00099 19.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CCP_MauG PF03150.14 AMK75215.1 - 2e-52 177.8 0.0 2e-47 161.6 0.0 2.3 2 0 0 2 2 2 2 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 AMK75215.1 - 9e-11 42.8 0.0 3.7e-07 31.2 0.0 3.0 2 1 0 2 2 2 2 Cytochrome c Cytochrome_C7 PF14522.6 AMK75215.1 - 0.0036 17.3 0.1 0.32 11.0 0.1 2.3 2 0 0 2 2 2 1 Cytochrome c7 and related cytochrome c Cytochrome_CBB3 PF13442.6 AMK75215.1 - 0.012 15.9 0.1 32 4.9 0.1 3.4 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 AMK75215.1 - 0.034 13.9 1.0 5.2 6.9 0.3 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF1924 PF09086.11 AMK75215.1 - 0.16 12.4 0.8 2.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) DUF2076 PF09849.9 AMK75216.1 - 3.8e-44 151.7 27.2 8.1e-43 147.3 27.2 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) hemP PF10636.9 AMK75218.1 - 1.1e-18 66.7 0.5 1.4e-18 66.4 0.5 1.1 1 0 0 1 1 1 1 Hemin uptake protein hemP TonB_C PF03544.14 AMK75219.1 - 1.2e-22 80.1 0.1 3.2e-22 78.7 0.1 1.7 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AMK75219.1 - 1.7e-05 25.0 2.7 3.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 TonB C terminal Ndc1_Nup PF09531.10 AMK75219.1 - 0.69 8.5 6.2 0.84 8.2 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MotA_ExbB PF01618.16 AMK75220.1 - 3.8e-31 107.5 0.2 6e-31 106.8 0.2 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AMK75221.1 - 1e-29 103.3 0.1 1.2e-29 103.1 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 AMK75221.1 - 0.35 11.1 2.8 0.55 10.5 2.4 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) TonB_dep_Rec PF00593.24 AMK75222.1 - 1.8e-45 156.7 16.0 1.8e-45 156.7 16.0 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK75222.1 - 4.2e-22 78.8 1.2 4.2e-22 78.8 1.2 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain PEP-CTERM PF07589.11 AMK75224.1 - 0.013 15.5 0.3 0.013 15.5 0.3 1.8 2 0 0 2 2 2 0 PEP-CTERM motif HemS PF05171.12 AMK75225.1 - 6.3e-53 178.1 0.0 6.7e-34 116.6 0.0 2.3 2 0 0 2 2 2 2 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 AMK75225.1 - 4.6e-39 133.3 0.0 5.7e-29 100.6 0.0 2.2 2 0 0 2 2 2 2 Haem utilisation ChuX/HutX RWP-RK PF02042.15 AMK75225.1 - 0.19 11.8 0.0 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 RWP-RK domain Putative_PNPOx PF01243.20 AMK75226.1 - 9.7e-15 54.5 0.1 1.4e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 AMK75226.1 - 0.0075 16.3 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Acetyltransf_6 PF13480.7 AMK75226.1 - 0.017 15.3 0.9 0.081 13.1 0.9 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peripla_BP_2 PF01497.18 AMK75227.1 - 1.6e-33 116.3 0.1 2e-33 115.9 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 AMK75228.1 - 9e-91 304.1 31.9 1.1e-90 303.8 31.9 1.0 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 AMK75229.1 - 4.9e-27 95.1 0.0 2.4e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 AMK75229.1 - 9.3e-08 31.8 0.0 0.0085 15.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK75229.1 - 6.3e-06 26.2 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK75229.1 - 1.6e-05 24.6 0.1 3.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 AMK75229.1 - 2e-05 24.9 0.0 3.5e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AMK75229.1 - 0.0011 19.5 0.0 0.0021 18.6 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 AMK75229.1 - 0.0013 19.0 0.5 0.02 15.2 0.5 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 AMK75229.1 - 0.0026 17.8 0.8 0.044 13.9 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_27 PF13514.6 AMK75229.1 - 0.0039 16.8 0.1 0.0089 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 AMK75229.1 - 0.0047 16.9 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 AMK75229.1 - 0.005 17.2 1.0 0.024 15.0 1.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AMK75229.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 AMK75229.1 - 0.014 15.4 0.1 0.023 14.8 0.1 1.4 1 1 0 1 1 1 0 Dynamin family AAA_33 PF13671.6 AMK75229.1 - 0.015 15.4 0.3 0.035 14.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AMK75229.1 - 0.044 13.4 0.1 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AMK75229.1 - 0.063 13.0 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 AMK75229.1 - 0.078 11.8 0.1 0.37 9.5 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 AMK75229.1 - 0.097 12.4 0.4 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AMK75229.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CEP63 PF17045.5 AMK75230.1 - 0.00075 19.5 1.7 0.00091 19.2 1.7 1.0 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Allexi_40kDa PF05549.11 AMK75230.1 - 0.027 14.0 0.8 0.033 13.7 0.8 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1690 PF07956.11 AMK75230.1 - 0.061 13.7 2.1 0.07 13.6 2.1 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TPR_MLP1_2 PF07926.12 AMK75230.1 - 0.096 12.8 6.2 0.11 12.5 6.2 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MscS_TM PF12794.7 AMK75232.1 - 0.0085 15.0 1.8 0.0089 14.9 1.8 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 UPF0697 PF15117.6 AMK75232.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 DUF2663 PF10864.8 AMK75232.1 - 0.27 11.7 3.4 0.22 11.9 1.1 1.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2663) DUF1129 PF06570.11 AMK75232.1 - 0.29 10.6 3.5 0.18 11.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF2631 PF10939.8 AMK75232.1 - 1.6 8.7 5.0 12 5.9 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2631) Insulin_TMD PF17870.1 AMK75232.1 - 10 6.3 10.3 2.2 8.4 0.1 3.1 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Peptidase_M16_C PF05193.21 AMK75233.1 - 9.9e-07 28.9 0.1 1.1e-06 28.8 0.1 1.0 1 0 0 1 1 1 1 Peptidase M16 inactive domain ABC_membrane PF00664.23 AMK75234.1 - 2.4e-19 70.1 4.5 3.2e-19 69.6 4.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_C39 PF03412.15 AMK75234.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family DUF3475 PF11961.8 AMK75234.1 - 0.066 13.3 0.0 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) PepSY_TM_like_2 PF16357.5 AMK75237.1 - 2.7e-12 47.1 1.2 5e-12 46.2 1.2 1.4 1 1 0 1 1 1 1 Putative PepSY_TM-like PepSY_TM PF03929.16 AMK75237.1 - 7.6e-11 42.2 4.9 1.7e-10 41.1 4.6 1.6 1 1 0 1 1 1 1 PepSY-associated TM region PKHD_C PF18331.1 AMK75238.1 - 1.6e-19 69.7 0.3 3.9e-19 68.4 0.3 1.7 1 0 0 1 1 1 1 PKHD-type hydroxylase C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 AMK75238.1 - 5.6e-13 49.6 0.0 8.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 AMK75238.1 - 1.6e-06 28.5 0.0 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_6 PF12852.7 AMK75238.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Cupin 2OG-FeII_Oxy_5 PF13759.6 AMK75238.1 - 0.12 12.9 0.0 0.38 11.2 0.0 1.8 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase TonB_dep_Rec PF00593.24 AMK75239.1 - 1.4e-29 104.3 22.4 2.1e-29 103.8 22.4 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK75239.1 - 8.4e-22 77.8 0.1 3.8e-21 75.7 0.1 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK75239.1 - 3.4e-07 29.6 3.6 3.4e-07 29.6 3.6 2.2 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family Methyltransf_11 PF08241.12 AMK75240.1 - 0.0071 17.0 0.0 0.014 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75240.1 - 0.019 15.7 0.0 0.056 14.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75240.1 - 0.028 15.2 0.0 0.048 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 AMK75241.1 - 1.9e-51 174.4 0.0 3.5e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheB_methylest PF01339.17 AMK75241.1 - 1.6e-35 122.3 0.0 7.2e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 CheB methylesterase PAS_3 PF08447.12 AMK75241.1 - 7.3e-33 112.7 0.8 4.5e-18 65.3 0.0 4.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AMK75241.1 - 9.6e-30 103.1 0.0 4e-15 56.0 0.0 4.8 4 0 0 4 4 4 3 PAS fold Response_reg PF00072.24 AMK75241.1 - 7.3e-29 100.2 0.1 1.9e-28 98.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AMK75241.1 - 1.6e-26 93.0 0.0 3.6e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AMK75241.1 - 1.4e-19 70.2 0.0 3.2e-06 27.4 0.0 5.2 5 0 0 5 5 4 4 PAS domain HisKA PF00512.25 AMK75241.1 - 1.3e-17 63.5 0.1 1.3e-17 63.5 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 AMK75241.1 - 2.9e-11 43.9 0.0 1.8e-10 41.3 0.0 2.4 3 0 0 3 3 1 1 PAS domain PAS PF00989.25 AMK75241.1 - 3.8e-11 43.0 0.0 0.027 14.5 0.0 5.3 4 1 0 4 4 4 3 PAS fold CheR_N PF03705.15 AMK75241.1 - 4e-10 39.3 0.2 7.9e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain PAS_8 PF13188.7 AMK75241.1 - 1.6e-06 28.0 0.0 0.074 13.1 0.0 3.7 3 0 0 3 3 3 2 PAS domain CENP-F_leu_zip PF10473.9 AMK75241.1 - 0.0082 16.2 12.5 0.0082 16.2 12.5 1.9 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 AMK75241.1 - 0.014 15.6 9.0 0.044 14.0 9.0 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Methyltransf_25 PF13649.6 AMK75241.1 - 0.016 15.9 0.4 3.1 8.6 0.0 4.2 3 1 0 3 3 3 0 Methyltransferase domain Spc7 PF08317.11 AMK75241.1 - 0.019 13.9 7.2 0.039 12.8 7.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.12 AMK75241.1 - 0.034 12.3 6.0 0.057 11.6 4.5 1.8 2 0 0 2 2 2 0 HOOK protein GRIP PF01465.20 AMK75241.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 GRIP domain Fez1 PF06818.15 AMK75241.1 - 0.16 12.4 5.2 0.43 11.0 5.2 1.7 1 0 0 1 1 1 0 Fez1 OmpH PF03938.14 AMK75241.1 - 0.21 11.9 3.1 0.79 10.1 1.7 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 AMK75241.1 - 0.21 11.8 2.7 0.88 9.8 2.7 2.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HMMR_N PF15905.5 AMK75241.1 - 0.24 10.9 7.7 0.51 9.8 7.7 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 AMK75241.1 - 0.36 10.3 7.4 0.72 9.3 7.4 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 AMK75241.1 - 0.7 10.0 13.1 0.16 12.1 9.0 2.1 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 AMK75241.1 - 1.6 8.2 11.5 2.3 7.7 8.8 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_TATA_bd PF12325.8 AMK75241.1 - 2.9 8.1 10.4 11 6.3 10.4 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HAP1_N PF04849.13 AMK75241.1 - 5 6.2 17.0 0.083 12.1 9.4 1.8 2 0 0 2 2 1 0 HAP1 N-terminal conserved region Robl_LC7 PF03259.17 AMK75242.1 - 2.9e-05 23.7 0.5 4.4e-05 23.2 0.5 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Fumerase PF05681.14 AMK75242.1 - 0.019 14.4 0.1 0.024 14.1 0.1 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Robl_LC7 PF03259.17 AMK75243.1 - 4.7e-09 35.9 0.3 5.9e-09 35.6 0.3 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain V4R PF02830.18 AMK75244.1 - 3.1e-14 52.7 0.6 4.7e-14 52.2 0.6 1.3 1 0 0 1 1 1 1 V4R domain DUF4923 PF16270.5 AMK75244.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) OmpA PF00691.20 AMK75245.1 - 7.1e-17 61.6 0.1 1.5e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 OmpA family CCDC53 PF10152.9 AMK75245.1 - 1.5 9.2 5.2 3.2 8.1 5.2 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex EAL PF00563.20 AMK75246.1 - 3.9e-44 151.0 0.0 5.1e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 EAL domain Radical_SAM PF04055.21 AMK75247.1 - 1.2e-14 55.1 0.0 1.2e-14 55.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AMK75247.1 - 0.001 19.3 1.3 0.0012 19.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Aminotran_5 PF00266.19 AMK75247.1 - 0.023 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V zf-C2HC5 PF06221.13 AMK75247.1 - 0.066 13.2 5.1 0.12 12.4 0.9 2.8 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Memo PF01875.17 AMK75248.1 - 3e-56 190.6 0.0 3.5e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein TetR_C_7 PF14246.6 AMK75248.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain AMMECR1 PF01871.17 AMK75249.1 - 3.1e-49 166.8 0.0 3.5e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 G6PD_C PF02781.16 AMK75250.1 - 1.3e-115 385.6 0.0 1.6e-115 385.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AMK75250.1 - 8.2e-52 176.4 0.0 2e-51 175.1 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.20 AMK75251.1 - 3.8e-48 164.3 0.1 4.2e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ILVD_EDD PF00920.21 AMK75252.1 - 1.5e-161 538.5 0.1 1.7e-161 538.3 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family 6PGD PF00393.19 AMK75253.1 - 9.7e-130 432.1 0.0 1.2e-129 431.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 AMK75253.1 - 2e-51 174.3 0.0 3.1e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 AMK75253.1 - 0.0026 17.8 0.1 0.0052 16.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 AMK75253.1 - 0.032 14.5 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 AMK75253.1 - 0.12 12.0 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 AMK75253.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AMK75253.1 - 0.17 12.5 0.0 0.51 11.0 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aldolase PF01081.19 AMK75254.1 - 1.7e-76 256.0 1.7 2e-76 255.8 1.7 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase DMRL_synthase PF00885.19 AMK75254.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase HMGL-like PF00682.19 AMK75254.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 HMGL-like G3P_antiterm PF04309.12 AMK75254.1 - 0.35 10.3 1.6 0.71 9.3 0.2 2.1 1 1 2 3 3 3 0 Glycerol-3-phosphate responsive antiterminator Dabb PF07876.12 AMK75255.1 - 3.1e-10 40.5 0.0 4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.16 AMK75255.1 - 0.00026 21.0 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase EthD PF07110.11 AMK75255.1 - 0.0042 18.2 0.0 0.0054 17.8 0.0 1.3 1 0 0 1 1 1 1 EthD domain Peptidase_M48 PF01435.18 AMK75256.1 - 1.2e-29 103.5 0.5 1.5e-28 99.9 0.5 2.1 1 1 0 1 1 1 1 Peptidase family M48 UbiA PF01040.18 AMK75256.1 - 0.014 14.7 0.8 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family MASE1 PF05231.14 AMK75256.1 - 0.022 13.9 1.5 0.075 12.2 0.1 2.0 2 0 0 2 2 2 0 MASE1 DUF898 PF05987.13 AMK75257.1 - 5e-109 364.5 23.7 5.6e-109 364.3 23.7 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Lambda_Bor PF06291.11 AMK75257.1 - 0.011 15.7 0.4 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 Bor protein PepSY_TM PF03929.16 AMK75257.1 - 1.6 8.4 6.7 0.66 9.6 3.5 1.9 1 1 0 1 1 1 0 PepSY-associated TM region DUF4234 PF14018.6 AMK75257.1 - 3.7 7.7 15.9 0.68 10.1 4.6 3.9 3 2 0 3 3 3 0 Domain of unknown function (DUF4234) UPF0182 PF03699.13 AMK75257.1 - 8.6 4.3 8.7 12 3.9 8.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) AhpC-TSA PF00578.21 AMK75258.1 - 1.2e-11 44.6 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK75258.1 - 1.9e-09 37.4 0.0 2.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 AMK75258.1 - 0.00094 19.6 0.0 0.0014 19.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain PTR2 PF00854.21 AMK75258.1 - 0.091 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 POT family TraF PF13728.6 AMK75258.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 1 1 2 2 2 0 F plasmid transfer operon protein AAA_16 PF13191.6 AMK75259.1 - 4e-42 144.5 0.1 1e-40 139.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.25 AMK75259.1 - 7.9e-26 91.0 0.0 1.7e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HATPase_c PF02518.26 AMK75259.1 - 7.3e-22 78.0 0.0 5e-21 75.3 0.0 2.5 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 AMK75259.1 - 8.3e-16 58.0 0.0 2.1e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HisKA PF00512.25 AMK75259.1 - 1.5e-11 44.2 0.0 1.5e-11 44.2 0.0 3.3 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 AMK75259.1 - 9.2e-10 39.3 0.1 2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AMK75259.1 - 1.9e-09 37.9 0.0 5e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.6 AMK75259.1 - 7.6e-09 35.7 19.2 0.0023 18.2 7.4 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat HATPase_c_5 PF14501.6 AMK75259.1 - 3.6e-05 23.6 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 GHKL domain GAF_3 PF13492.6 AMK75259.1 - 0.00014 22.2 0.1 0.00056 20.3 0.1 2.2 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.6 AMK75259.1 - 0.0062 16.8 0.0 0.067 13.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain HATPase_c_3 PF13589.6 AMK75259.1 - 0.012 15.4 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_18 PF13238.6 AMK75259.1 - 0.014 16.0 0.0 0.64 10.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain TPR_14 PF13428.6 AMK75259.1 - 0.026 15.3 10.2 5.7 8.0 0.1 5.0 4 1 1 5 5 3 0 Tetratricopeptide repeat DUF1525 PF07511.11 AMK75259.1 - 0.03 14.5 0.4 8.9 6.5 0.0 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1525) TPR_10 PF13374.6 AMK75259.1 - 0.031 14.1 4.0 0.35 10.8 1.1 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Kdo PF06293.14 AMK75259.1 - 0.034 13.5 0.2 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transcrip_reg PF01709.20 AMK75259.1 - 0.05 13.0 0.4 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator AAA_5 PF07728.14 AMK75259.1 - 0.059 13.4 0.0 0.94 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_16 PF13432.6 AMK75259.1 - 0.074 13.7 7.6 5.5 7.7 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75259.1 - 0.088 13.0 16.2 2.3 8.5 0.5 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat NACHT PF05729.12 AMK75259.1 - 0.11 12.5 0.1 0.57 10.1 0.0 2.4 2 0 0 2 2 1 0 NACHT domain DUF2791 PF10923.8 AMK75259.1 - 0.13 11.0 4.0 0.61 8.9 0.2 2.3 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) ZapB PF06005.12 AMK75259.1 - 1.2 9.7 5.3 4.2 7.9 0.0 3.6 3 0 0 3 3 3 0 Cell division protein ZapB TPR_8 PF13181.6 AMK75259.1 - 1.7 9.1 5.2 6.2 7.3 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1657 PF07870.11 AMK75259.1 - 6.8 6.7 8.6 0.19 11.6 0.5 2.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1657) Response_reg PF00072.24 AMK75260.1 - 8.9e-25 87.0 0.1 1.3e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain KaiB PF07689.12 AMK75260.1 - 1.1e-07 31.5 0.1 5.6e-07 29.2 0.1 2.0 1 1 1 2 2 2 1 KaiB domain EAL PF00563.20 AMK75261.1 - 1.7e-75 253.6 0.0 3.1e-75 252.7 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK75261.1 - 2e-54 183.7 0.1 3.4e-54 182.9 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AMK75261.1 - 1.1e-32 112.4 0.2 1.6e-14 53.9 0.0 5.1 3 2 1 4 4 4 3 PAS fold PAS_9 PF13426.7 AMK75261.1 - 2.8e-28 98.2 0.2 5.4e-13 49.1 0.1 5.1 4 1 0 4 4 4 3 PAS domain PAS_8 PF13188.7 AMK75261.1 - 5.9e-26 90.0 1.3 1.2e-08 34.7 0.0 4.5 4 0 0 4 4 4 4 PAS domain PAS_4 PF08448.10 AMK75261.1 - 5.9e-23 81.2 0.0 7.9e-06 26.1 0.0 4.6 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.12 AMK75261.1 - 3.4e-22 78.5 2.5 5.3e-14 52.3 0.1 3.8 4 0 0 4 4 4 2 PAS fold PAS_7 PF12860.7 AMK75261.1 - 7.9e-07 29.2 0.0 0.35 11.0 0.0 4.7 4 0 0 4 4 4 2 PAS fold Thaumatin PF00314.17 AMK75261.1 - 0.28 10.8 0.1 0.48 10.0 0.1 1.3 1 0 0 1 1 1 0 Thaumatin family Ribul_P_3_epim PF00834.19 AMK75262.1 - 1.7e-90 301.8 0.1 1.9e-90 301.6 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AMK75262.1 - 3e-05 23.9 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 AMK75262.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Autotransporter PF03797.19 AMK75263.1 - 1.6e-53 181.9 17.9 1.6e-53 181.9 17.9 1.8 2 0 0 2 2 2 1 Autotransporter beta-domain Calx-beta PF03160.14 AMK75263.1 - 5.5e-07 29.7 0.1 1.3e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Calx-beta domain Glyco_tran_28_C PF04101.16 AMK75264.1 - 5.6e-07 29.7 0.2 1.2e-06 28.6 0.3 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 AMK75264.1 - 1.7e-05 24.2 0.0 0.0091 15.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 UDPGT PF00201.18 AMK75264.1 - 0.0061 15.4 0.1 0.012 14.4 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Inositol_P PF00459.25 AMK75265.1 - 1.8e-55 188.4 0.1 2.3e-55 188.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Ammonium_transp PF00909.21 AMK75266.1 - 5.4e-117 390.8 36.0 6.2e-117 390.7 36.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family P-II PF00543.22 AMK75267.1 - 4e-43 146.2 2.6 4.5e-43 146.0 2.6 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II SPOUT_MTase_2 PF14419.6 AMK75267.1 - 0.03 13.7 0.1 0.069 12.5 0.0 1.6 1 1 1 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP DUF3240 PF11582.8 AMK75267.1 - 0.049 13.8 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) Cdc6_C PF09079.11 AMK75267.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Ammonium_transp PF00909.21 AMK75268.1 - 1.6e-109 366.3 42.9 1.9e-109 366.0 42.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family P-II PF00543.22 AMK75269.1 - 5.3e-43 145.8 2.2 5.9e-43 145.6 2.2 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 AMK75269.1 - 0.021 15.0 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3240) SPOUT_MTase_2 PF14419.6 AMK75269.1 - 0.035 13.5 0.2 0.31 10.4 0.1 2.0 1 1 1 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP CdAMP_rec PF06153.11 AMK75269.1 - 0.05 13.8 0.8 0.37 11.0 0.8 1.9 1 1 0 1 1 1 0 Cyclic-di-AMP receptor BBP2 PF07642.11 AMK75271.1 - 1.2e-93 314.0 17.7 1.4e-93 313.8 17.7 1.0 1 0 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 Gln-synt_C PF00120.24 AMK75272.1 - 2.4e-136 454.3 0.0 2.8e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AMK75272.1 - 1.1e-32 111.5 0.7 2e-32 110.8 0.7 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SDH_alpha PF03313.15 AMK75274.1 - 7e-106 353.6 3.3 8.7e-106 353.3 3.3 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 AMK75274.1 - 8.3e-59 198.4 0.0 1.5e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain SAM_4 PF18017.1 AMK75276.1 - 0.057 13.4 0.2 0.065 13.2 0.2 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Bax1-I PF01027.20 AMK75277.1 - 1.2e-41 142.8 36.8 1.4e-41 142.6 36.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Bac_globin PF01152.21 AMK75278.1 - 4.3e-39 133.4 0.0 4.8e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Metal_hydrol PF10118.9 AMK75278.1 - 0.056 13.2 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase LapD_MoxY_N PF16448.5 AMK75279.1 - 1.6e-40 137.8 0.0 6.7e-40 135.8 0.0 2.1 3 0 0 3 3 3 1 LapD/MoxY periplasmic domain EAL PF00563.20 AMK75279.1 - 7.1e-32 110.8 0.5 2e-31 109.4 0.5 1.7 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK75279.1 - 1.5e-10 41.1 0.2 3.5e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain RTP1_C1 PF10363.9 AMK75279.1 - 0.082 13.1 0.1 0.35 11.1 0.1 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Peptidase_M75 PF09375.10 AMK75279.1 - 0.26 10.7 1.5 0.37 10.2 0.2 1.9 2 0 0 2 2 2 0 Imelysin Peptidase_C93 PF06035.11 AMK75280.1 - 2.2e-17 63.3 0.0 3.1e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial transglutaminase-like cysteine proteinase BTLCP Transglut_core PF01841.19 AMK75280.1 - 0.015 15.8 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF45 PF01863.17 AMK75281.1 - 5.4e-59 199.7 2.8 6.7e-59 199.4 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AMK75281.1 - 0.0023 18.0 1.0 0.0043 17.2 1.0 1.4 1 0 0 1 1 1 1 WLM domain Par3_HAL_N_term PF12053.8 AMK75281.1 - 0.072 13.3 0.2 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins SprT-like PF10263.9 AMK75281.1 - 0.09 12.6 0.9 0.21 11.4 0.9 1.9 1 1 0 1 1 1 0 SprT-like family AhpC-TSA PF00578.21 AMK75282.1 - 2.9e-11 43.3 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 AMK75282.1 - 3.1e-09 36.7 0.0 1.7e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 AMK75282.1 - 6.1e-08 32.5 0.0 8.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 AMK75282.1 - 1.5e-07 31.8 0.0 2.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AMK75282.1 - 1.1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 AMK75282.1 - 6e-06 26.2 0.0 8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2518 PF10726.9 AMK75282.1 - 0.083 12.5 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of function (DUF2518) Thioredoxin_9 PF14595.6 AMK75282.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin PilZ PF07238.14 AMK75283.1 - 2.9e-13 50.0 0.0 3.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 PilZ domain Yop-YscD_cpl PF16697.5 AMK75284.1 - 1.6e-13 50.7 1.0 1.8e-08 34.6 0.1 3.1 2 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 AMK75284.1 - 6.3e-12 45.7 0.1 8.8e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 FHA domain PTA_PTB PF01515.19 AMK75285.1 - 1.9e-128 428.3 1.1 3.1e-128 427.6 0.7 1.5 2 0 0 2 2 2 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 AMK75285.1 - 5.3e-28 96.9 0.4 4e-27 94.1 0.0 2.6 3 0 0 3 3 3 1 DRTGG domain AAA_26 PF13500.6 AMK75285.1 - 1.9e-24 86.6 0.0 9e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF3280 PF11684.8 AMK75286.1 - 6e-17 62.4 0.0 7.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) LpoB PF13036.6 AMK75286.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB Acetate_kinase PF00871.17 AMK75287.1 - 2.8e-145 483.9 0.0 3.3e-145 483.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family ROK PF00480.20 AMK75287.1 - 0.00043 19.9 0.4 0.00093 18.8 0.4 1.4 1 1 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 AMK75287.1 - 0.0041 16.6 0.1 0.0086 15.6 0.1 1.7 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family TonB_dep_Rec PF00593.24 AMK75288.1 - 8.1e-38 131.5 17.4 1e-37 131.1 17.4 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK75288.1 - 3.2e-20 72.7 4.6 3.7e-20 72.5 0.4 2.8 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK75288.1 - 3.3e-08 32.9 2.8 3e-07 29.8 0.0 2.8 3 0 0 3 3 3 1 Outer membrane protein beta-barrel family cobW PF02492.19 AMK75289.1 - 1.1e-33 116.3 0.0 1.5e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 AMK75289.1 - 3e-14 52.7 0.0 1.3e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_28 PF13521.6 AMK75289.1 - 0.0039 17.4 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AMK75289.1 - 0.096 12.8 0.1 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 AMK75289.1 - 0.13 11.7 0.1 0.33 10.4 0.1 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 AMK75289.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MCPsignal PF00015.21 AMK75290.1 - 1.4e-40 138.9 16.4 1.4e-40 138.9 16.4 3.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AMK75290.1 - 9.5e-09 35.5 3.4 3.8e-08 33.6 0.1 3.2 3 0 0 3 3 3 1 HAMP domain FlgN PF05130.12 AMK75290.1 - 0.043 14.3 12.4 3.3 8.2 0.2 3.6 2 1 1 3 3 3 0 FlgN protein DUF948 PF06103.11 AMK75290.1 - 0.24 11.7 24.1 0.26 11.6 0.6 5.4 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 AMK75290.1 - 0.53 10.3 25.9 2.4 8.2 1.4 4.2 2 2 2 4 4 4 0 Laminin Domain II Goodbye PF17109.5 AMK75290.1 - 0.9 10.0 6.6 1.2 9.6 1.7 3.0 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain BLOC1_2 PF10046.9 AMK75290.1 - 1.7 9.0 13.9 3.2 8.1 0.5 4.5 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 AMK75290.1 - 1.9 8.6 11.7 1.3 9.1 2.2 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 AMK75290.1 - 4 8.2 8.2 7.1 7.4 0.8 3.7 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) Nup54 PF13874.6 AMK75290.1 - 9.7 6.3 10.6 1.2 9.2 1.6 2.9 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Ferritin PF00210.24 AMK75291.1 - 7.3e-40 136.2 1.3 8.4e-40 136.0 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AMK75291.1 - 0.071 13.5 0.3 0.14 12.5 0.3 1.5 1 1 0 1 1 1 0 Rubrerythrin TPPII_N PF12583.8 AMK75291.1 - 0.075 13.6 0.1 0.15 12.7 0.0 1.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Response_reg PF00072.24 AMK75292.1 - 3.3e-41 140.0 0.7 1.2e-26 93.0 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain PAS_3 PF08447.12 AMK75292.1 - 2.4e-31 107.9 1.1 1e-19 70.6 0.1 3.3 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 AMK75292.1 - 2.2e-24 86.1 0.0 5.1e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AMK75292.1 - 2.1e-21 76.1 0.0 7.1e-20 71.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK75292.1 - 1.1e-19 70.5 0.2 4.1e-12 46.1 0.0 3.8 4 0 0 4 4 4 2 PAS fold HisKA PF00512.25 AMK75292.1 - 1.5e-17 63.4 0.1 1.5e-17 63.4 0.1 2.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AMK75292.1 - 3e-14 53.2 1.0 4.1e-08 33.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold Hpt PF01627.23 AMK75292.1 - 2.4e-10 40.5 0.7 2.4e-10 40.5 0.7 4.0 4 1 1 5 5 5 1 Hpt domain PAS_8 PF13188.7 AMK75292.1 - 3.3e-06 27.0 0.0 8.9e-05 22.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain Response_reg PF00072.24 AMK75293.1 - 2.9e-18 66.1 0.0 3.4e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AMK75294.1 - 3.2e-45 153.2 0.0 2.9e-25 88.9 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK75294.1 - 1.9e-24 86.0 0.3 5.5e-24 84.5 0.3 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AMK75294.1 - 2.1e-20 72.5 5.2 2.8e-09 36.9 0.0 3.4 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AMK75294.1 - 7e-19 68.1 0.1 3.5e-08 33.7 0.0 3.5 4 0 0 4 4 3 2 PAS fold DUF4118 PF13493.6 AMK75294.1 - 9.1e-18 64.0 1.8 1.8e-17 63.0 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) PAS_9 PF13426.7 AMK75294.1 - 6.7e-13 48.8 0.0 7.1e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AMK75294.1 - 1.8e-12 47.4 0.1 6.1e-09 36.1 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AMK75294.1 - 7.3e-10 38.8 0.0 3.1e-07 30.4 0.0 2.7 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 AMK75294.1 - 3.3e-07 30.2 0.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK75294.1 - 8.5e-07 28.8 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 GHKL domain PAS_8 PF13188.7 AMK75294.1 - 5.6e-06 26.3 0.2 0.0052 16.8 0.0 3.3 3 0 0 3 3 3 1 PAS domain HATPase_c_2 PF13581.6 AMK75294.1 - 6.2e-05 23.0 0.1 0.22 11.5 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AMK75294.1 - 0.0044 17.2 0.3 17 5.6 0.0 4.3 4 1 0 4 4 4 0 PAS fold HPTransfase PF10090.9 AMK75294.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain MASE1 PF05231.14 AMK75294.1 - 0.15 11.2 11.1 0.23 10.6 11.1 1.2 1 0 0 1 1 1 0 MASE1 PAS_3 PF08447.12 AMK75295.1 - 4.6e-50 167.8 0.1 1.7e-15 57.1 0.0 4.6 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 AMK75295.1 - 2.6e-36 124.2 5.4 4.8e-10 39.7 0.0 6.6 6 1 0 6 6 6 5 PAS fold PAS_9 PF13426.7 AMK75295.1 - 6.4e-34 116.3 0.0 1.1e-13 51.4 0.0 5.3 5 0 0 5 5 5 4 PAS domain PAS PF00989.25 AMK75295.1 - 4.8e-26 91.0 0.4 6.1e-12 45.5 0.0 5.3 5 0 0 5 5 5 4 PAS fold DUF4118 PF13493.6 AMK75295.1 - 7.6e-18 64.3 7.7 1.4e-17 63.4 7.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) PAS_8 PF13188.7 AMK75295.1 - 1.2e-10 41.2 0.2 0.018 15.1 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS_7 PF12860.7 AMK75295.1 - 2.2e-06 27.8 0.2 0.047 13.9 0.0 4.7 5 1 0 5 5 5 2 PAS fold PAS_4 PF08448.10 AMK75296.1 - 9.4e-28 96.7 0.1 6.3e-21 74.7 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AMK75296.1 - 9e-20 70.8 0.1 5.2e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AMK75296.1 - 8.5e-19 67.7 0.2 8.3e-08 32.4 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 AMK75296.1 - 1.3e-11 44.3 0.8 1.2e-07 31.6 0.1 3.1 3 0 0 3 3 3 2 PAS domain dCache_1 PF02743.18 AMK75296.1 - 6.7e-09 35.9 0.0 3.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Cache domain PAS_3 PF08447.12 AMK75296.1 - 4.7e-06 26.8 0.0 1.3e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold dCache_3 PF14827.6 AMK75296.1 - 0.0026 17.5 0.0 0.75 9.4 0.0 2.8 3 0 0 3 3 3 1 Double sensory domain of two-component sensor kinase MatE PF01554.18 AMK75296.1 - 0.11 12.1 3.2 0.23 11.1 2.3 1.9 1 1 1 2 2 2 0 MatE MamL-1 PF09596.10 AMK75296.1 - 0.13 12.5 1.3 11 6.3 0.1 2.7 2 0 0 2 2 2 0 MamL-1 domain K-box PF01486.17 AMK75296.1 - 0.23 11.7 4.9 0.14 12.4 2.2 2.0 2 0 0 2 2 2 0 K-box region Abhydrolase_9_N PF15420.6 AMK75296.1 - 0.48 10.4 5.7 3.2 7.7 1.5 2.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus bZIP_2 PF07716.15 AMK75296.1 - 1.4 9.0 7.3 0.61 10.2 2.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Response_reg PF00072.24 AMK75297.1 - 1.3e-23 83.3 0.1 2.1e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_2 PF13581.6 AMK75297.1 - 5.7e-10 39.2 0.0 1.2e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 AMK75298.1 - 7.8e-27 93.7 0.2 1.8e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HD PF01966.22 AMK75298.1 - 1.5e-14 54.2 1.1 2.6e-14 53.5 0.3 1.9 3 0 0 3 3 3 1 HD domain HD_5 PF13487.6 AMK75298.1 - 5.6e-14 52.1 0.0 4.8e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 HD domain NurA PF09376.10 AMK75298.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.7 1 1 0 1 1 1 0 NurA domain TGT PF01702.18 AMK75299.1 - 2.5e-154 513.6 0.0 3.1e-154 513.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LpxB PF02684.15 AMK75300.1 - 1e-101 340.5 0.0 1.2e-101 340.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Epimerase_2 PF02350.19 AMK75300.1 - 2.8e-05 23.2 0.0 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase DUF354 PF04007.12 AMK75300.1 - 0.0066 15.6 0.0 0.011 14.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF354) DegT_DnrJ_EryC1 PF01041.17 AMK75301.1 - 8.3e-129 430.0 0.0 9.5e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 AMK75301.1 - 4e-07 29.6 0.2 7.7e-07 28.7 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AMK75301.1 - 4.3e-06 25.5 0.1 6.4e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 AMK75301.1 - 4.8e-05 22.5 0.1 7.4e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PEP_mutase PF13714.6 AMK75301.1 - 0.044 13.2 0.7 0.26 10.7 0.2 2.2 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase GFO_IDH_MocA PF01408.22 AMK75302.1 - 1e-31 110.3 1.5 1.6e-31 109.6 1.5 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 AMK75302.1 - 0.00012 22.2 0.3 0.0007 19.7 0.1 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AMK75302.1 - 0.00013 21.6 0.2 0.0017 17.9 0.2 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 AMK75302.1 - 0.00024 20.7 1.1 0.00029 20.4 0.3 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain OCD_Mu_crystall PF02423.15 AMK75302.1 - 0.0027 16.7 0.3 0.0041 16.1 0.3 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 AMK75302.1 - 0.0036 17.6 1.3 0.016 15.5 0.7 2.4 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AMK75302.1 - 0.0054 16.1 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 AMK75302.1 - 0.0062 17.2 1.4 0.0062 17.2 1.4 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 AMK75302.1 - 0.022 15.4 0.1 0.054 14.2 0.1 1.8 1 0 0 1 1 1 0 CoA binding domain TrkA_N PF02254.18 AMK75302.1 - 0.03 14.6 2.2 0.72 10.1 0.0 2.7 2 1 1 3 3 3 0 TrkA-N domain DapB_N PF01113.20 AMK75302.1 - 0.037 14.2 0.1 0.07 13.3 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 AMK75302.1 - 0.077 13.4 0.9 0.12 12.8 0.2 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 AMK75302.1 - 0.1 13.1 0.5 0.21 12.1 0.5 1.5 1 0 0 1 1 1 0 CoA binding domain ABC_tran_CTD PF16326.5 AMK75303.1 - 0.0071 16.6 2.4 0.19 12.0 0.5 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain FlgN PF05130.12 AMK75303.1 - 0.014 15.9 0.5 0.025 15.1 0.5 1.4 1 0 0 1 1 1 0 FlgN protein DUF3235 PF11574.8 AMK75303.1 - 0.02 15.8 2.0 0.045 14.6 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) HR1 PF02185.16 AMK75303.1 - 0.055 13.6 4.3 0.044 13.9 1.8 1.9 2 0 0 2 2 2 0 Hr1 repeat TerB PF05099.13 AMK75303.1 - 0.096 12.6 1.1 0.19 11.7 1.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB DUF2383 PF09537.10 AMK75303.1 - 0.13 12.6 1.2 0.28 11.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) OMP_b-brl PF13505.6 AMK75303.1 - 0.22 11.6 5.5 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Outer membrane protein beta-barrel domain MerR-DNA-bind PF09278.11 AMK75303.1 - 0.23 12.0 2.8 15 6.2 1.0 2.3 2 0 0 2 2 2 0 MerR, DNA binding BMFP PF04380.13 AMK75303.1 - 0.24 11.9 4.3 0.59 10.6 0.9 2.2 2 0 0 2 2 2 0 Membrane fusogenic activity Csm1_N PF18504.1 AMK75303.1 - 0.34 11.3 3.3 1.1 9.6 1.2 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Cytochrome_C7 PF14522.6 AMK75304.1 - 3.4e-08 33.4 8.1 1.3e-06 28.3 4.3 2.2 1 1 1 2 2 2 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AMK75304.1 - 1.6e-07 30.9 21.3 0.0026 17.4 6.3 4.0 2 2 2 4 4 4 4 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 AMK75304.1 - 8.5e-05 22.9 12.9 0.016 15.6 12.9 2.6 1 1 0 1 1 1 1 Cytochrome c3 Cytochrom_CIII PF02085.16 AMK75304.1 - 0.00018 21.8 10.2 0.076 13.4 0.6 2.2 1 1 1 2 2 2 2 Class III cytochrome C family Cytochrom_NNT PF03264.14 AMK75304.1 - 0.00057 19.6 8.8 0.013 15.2 0.4 3.0 2 1 0 2 2 2 2 NapC/NirT cytochrome c family, N-terminal region DUF1924 PF09086.11 AMK75304.1 - 0.092 13.1 15.6 0.55 10.6 0.9 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF1924) Cytochrome_C554 PF13435.6 AMK75304.1 - 0.1 13.5 13.0 0.93 10.5 1.5 3.5 1 1 3 4 4 4 0 Cytochrome c554 and c-prime WHAMM-JMY_N PF15920.5 AMK75304.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.8 4 0 0 4 4 4 0 N-terminal of Junction-mediating and WASP homolog-associated CCP_MauG PF03150.14 AMK75304.1 - 0.24 12.0 17.4 0.4 11.3 0.6 3.8 1 1 3 4 4 4 0 Di-haem cytochrome c peroxidase Apocytochr_F_N PF16639.5 AMK75304.1 - 0.42 10.9 2.2 21 5.4 0.1 2.8 1 1 2 3 3 3 0 Apocytochrome F, N-terminal Cytochrome_P460 PF16694.5 AMK75304.1 - 2.2 8.6 11.5 22 5.4 0.8 3.9 3 1 1 4 4 4 0 Cytochrome P460 Cytochrome_CBB3 PF13442.6 AMK75304.1 - 6.8 7.1 16.4 2.6 8.4 0.5 4.0 2 1 2 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III T7SS_ESX_EspC PF10824.8 AMK75305.1 - 0.0042 17.5 0.5 0.0042 17.5 0.5 1.6 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm HTH_Tnp_4 PF13613.6 AMK75305.1 - 0.12 12.1 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease MCPsignal PF00015.21 AMK75306.1 - 6.5e-48 162.8 45.4 2.7e-46 157.5 28.6 3.5 2 2 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AMK75306.1 - 2.9e-05 24.4 0.6 0.00033 21.0 0.0 3.3 3 1 0 3 3 3 1 HAMP domain T2SSF PF00482.23 AMK75306.1 - 0.011 15.7 12.1 2 8.4 1.4 4.4 3 2 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF948 PF06103.11 AMK75306.1 - 0.019 15.2 38.9 0.11 12.7 0.0 7.3 5 1 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 AMK75306.1 - 0.021 15.3 15.7 0.72 10.3 0.6 3.3 3 0 0 3 3 3 0 Fez1 DUF4164 PF13747.6 AMK75306.1 - 0.13 12.5 0.1 0.13 12.5 0.1 5.0 4 2 0 4 4 4 0 Domain of unknown function (DUF4164) DUF745 PF05335.13 AMK75306.1 - 2.3 7.9 45.4 0.35 10.6 15.6 4.8 3 1 2 5 5 5 0 Protein of unknown function (DUF745) DUF2203 PF09969.9 AMK75306.1 - 3 8.6 21.9 4.3 8.1 1.6 5.2 3 3 2 5 5 5 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 AMK75306.1 - 3.4 6.5 12.1 0.76 8.6 0.2 2.6 1 1 1 2 2 2 0 LMBR1-like membrane protein Caskin-tail PF16632.5 AMK75306.1 - 5 7.6 8.6 1.5 9.2 0.1 4.2 4 0 0 4 4 4 0 C-terminal region of Caskin Uma2 PF05685.12 AMK75307.1 - 1.5e-37 128.8 0.0 1.7e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease E1-E2_ATPase PF00122.20 AMK75308.1 - 1.2e-55 187.9 3.3 1.2e-55 187.9 3.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AMK75308.1 - 6.8e-44 150.7 6.1 1.4e-43 149.6 6.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AMK75308.1 - 5.1e-14 52.5 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 AMK75308.1 - 3.7e-06 27.5 0.1 1e-05 26.0 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK75308.1 - 3.3e-05 23.8 1.3 0.0042 16.9 0.2 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Peptidase_S10 PF00450.22 AMK75308.1 - 0.0066 15.9 0.0 0.0094 15.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HMA PF00403.26 AMK75309.1 - 6.5e-12 45.7 0.7 7.1e-12 45.6 0.7 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain YbaB_DNA_bd PF02575.16 AMK75309.1 - 0.0051 17.0 0.3 0.0071 16.6 0.3 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HDOD PF08668.12 AMK75310.1 - 3.1e-18 66.0 0.3 4.6e-18 65.4 0.3 1.2 1 0 0 1 1 1 1 HDOD domain EAL PF00563.20 AMK75310.1 - 4.2e-17 62.5 0.0 1.1e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 EAL domain ULD PF16534.5 AMK75310.1 - 0.087 12.9 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like oligomerisation domain of SATB Rhodanese PF00581.20 AMK75311.1 - 9.9e-15 55.0 0.0 1.2e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain FlgO PF17680.1 AMK75311.1 - 0.061 13.1 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 FlgO protein DUF489 PF04356.12 AMK75312.1 - 1.7e-69 233.7 4.8 2e-69 233.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DUF4404 PF14357.6 AMK75312.1 - 0.11 13.1 0.2 0.23 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CBM_1 PF00734.18 AMK75312.1 - 0.16 12.0 1.1 0.28 11.2 1.1 1.4 1 0 0 1 1 1 0 Fungal cellulose binding domain Fapy_DNA_glyco PF01149.24 AMK75313.1 - 4.9e-34 117.4 0.0 8.3e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AMK75313.1 - 1e-27 95.9 0.0 1.7e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AMK75313.1 - 9.8e-07 28.5 3.0 1.9e-06 27.6 3.0 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zinc-ribbons_6 PF07191.12 AMK75313.1 - 0.11 12.5 2.7 0.094 12.7 1.5 1.5 2 0 0 2 2 2 0 zinc-ribbons FbpA PF05833.11 AMK75313.1 - 0.28 9.9 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SpoIIE PF07228.12 AMK75314.1 - 6e-31 107.9 0.0 9.1e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) HATPase_c_2 PF13581.6 AMK75314.1 - 5e-10 39.4 0.0 3.4e-09 36.7 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain PsiE PF06146.12 AMK75316.1 - 1e-11 45.0 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Phosphate-starvation-inducible E DUF3530 PF12048.8 AMK75317.1 - 4.1e-38 131.6 1.8 4.8e-18 65.6 0.1 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF3530) DLH PF01738.18 AMK75317.1 - 0.00021 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 AMK75317.1 - 0.00051 19.9 0.0 0.002 18.0 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 AMK75317.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 AMK75317.1 - 0.038 13.7 0.0 3.2 7.4 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 AMK75317.1 - 0.062 12.6 0.1 0.13 11.5 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF1488 PF07369.11 AMK75317.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Abhydrolase_6 PF12697.7 AMK75317.1 - 0.12 12.9 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thi4 PF01946.17 AMK75317.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AI-2E_transport PF01594.16 AMK75318.1 - 3e-61 207.4 31.2 3.5e-61 207.2 31.2 1.0 1 0 0 1 1 1 1 AI-2E family transporter NiFe-hyd_HybE PF11939.8 AMK75318.1 - 0.28 11.1 0.7 9.6 6.1 0.1 2.2 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE DUF3084 PF11283.8 AMK75318.1 - 1.3 9.1 7.2 0.096 12.7 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3084) SNARE_assoc PF09335.11 AMK75319.1 - 1.1e-22 80.8 7.5 1.1e-22 80.8 7.5 1.7 3 0 0 3 3 3 1 SNARE associated Golgi protein TRAM_LAG1_CLN8 PF03798.16 AMK75319.1 - 0.92 9.2 7.1 0.062 13.0 1.4 1.8 2 0 0 2 2 2 0 TLC domain CSD PF00313.22 AMK75320.1 - 1.5e-12 47.2 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AMK75320.1 - 3.7e-05 23.3 0.7 6.1e-05 22.6 0.2 1.6 2 0 0 2 2 2 1 Ribonuclease B OB domain MMADHC PF10229.9 AMK75321.1 - 0.021 14.6 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein ATP-synt_F PF01990.17 AMK75321.1 - 0.088 13.1 0.2 0.18 12.1 0.1 1.7 2 1 0 2 2 2 0 ATP synthase (F/14-kDa) subunit SnoaL_2 PF12680.7 AMK75322.1 - 1.6e-18 67.2 0.2 1.9e-18 67.0 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AMK75322.1 - 3.1e-11 43.2 0.1 3.5e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.20 AMK75322.1 - 1.9e-06 28.4 0.1 2.5e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 AMK75322.1 - 1.9e-05 25.0 0.0 2.6e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AMK75322.1 - 3e-05 24.3 0.1 5.2e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 AMK75322.1 - 0.0005 20.2 0.1 0.00057 20.0 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4878 PF12870.7 AMK75322.1 - 0.0035 17.6 0.2 0.0049 17.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) DUF4829 PF16111.5 AMK75322.1 - 0.034 14.9 0.1 0.045 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) Tim44 PF04280.15 AMK75322.1 - 0.039 14.1 0.2 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 Tim44-like domain CDP-OH_P_transf PF01066.21 AMK75322.1 - 0.075 13.8 0.0 0.075 13.8 0.0 1.3 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase dNK PF01712.19 AMK75322.1 - 0.084 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF4904 PF16247.5 AMK75322.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) MecA_N PF05223.11 AMK75322.1 - 0.13 12.5 0.2 0.89 9.8 0.0 1.9 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Exo70 PF03081.15 AMK75322.1 - 0.19 10.8 0.3 0.25 10.4 0.3 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit CobA_CobO_BtuR PF02572.15 AMK75323.1 - 1.7e-61 207.4 0.1 2e-61 207.3 0.1 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PEP-CTERM PF07589.11 AMK75326.1 - 0.0074 16.3 1.2 0.0074 16.3 1.2 1.9 2 0 0 2 2 2 1 PEP-CTERM motif VPDSG-CTERM PF18205.1 AMK75326.1 - 0.11 12.4 0.7 0.11 12.4 0.7 2.2 2 0 0 2 2 2 0 VPDSG-CTERM motif PfkB PF00294.24 AMK75328.1 - 1.8e-47 162.1 0.0 2.1e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AMK75328.1 - 0.00039 19.9 0.0 0.0006 19.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase UTRA PF07702.13 AMK75329.1 - 7.8e-30 103.6 0.0 1.5e-29 102.7 0.0 1.4 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 AMK75329.1 - 2.3e-13 49.6 0.0 6.1e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 AMK75329.1 - 0.00044 20.2 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 AMK75329.1 - 0.0028 17.4 0.1 0.0066 16.2 0.1 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 AMK75329.1 - 0.0059 16.1 0.2 0.025 14.1 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AMK75329.1 - 0.03 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 HTH domain Cob_adeno_trans PF01923.18 AMK75329.1 - 0.039 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase HTH_AsnC-type PF13404.6 AMK75329.1 - 0.05 13.4 0.5 0.13 12.1 0.5 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_50 PF18024.1 AMK75329.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AMK75329.1 - 0.16 11.8 0.3 0.6 10.0 0.1 2.1 1 1 1 2 2 2 0 IclR helix-turn-helix domain PQ-loop PF04193.14 AMK75330.1 - 3e-12 46.1 0.8 3e-12 46.1 0.8 1.8 2 1 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 AMK75330.1 - 2.3e-07 30.8 1.4 2.5e-07 30.6 1.4 1.2 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 AMK75330.1 - 0.02 14.9 1.8 0.026 14.6 1.8 1.2 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF5353 PF17304.2 AMK75330.1 - 0.52 10.1 3.5 5.8 6.7 0.6 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5353) Hema_stalk PF08720.10 AMK75331.1 - 0.033 13.9 0.1 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk DUF2556 PF10831.8 AMK75331.1 - 0.33 10.9 2.1 0.57 10.2 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) DUF4307 PF14155.6 AMK75331.1 - 1.6 8.6 3.6 2.4 8.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) FtsK_SpoIIIE PF01580.18 AMK75332.1 - 1e-67 228.1 0.8 2.7e-67 226.7 0.8 1.7 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_4TM PF13491.6 AMK75332.1 - 3.2e-40 137.6 17.0 4.6e-40 137.1 17.0 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE FtsK_alpha PF17854.1 AMK75332.1 - 1.6e-28 98.8 0.1 3.4e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 AMK75332.1 - 2.9e-27 94.2 2.2 4.9e-27 93.5 0.1 2.4 2 0 0 2 2 2 1 Ftsk gamma domain AAA_10 PF12846.7 AMK75332.1 - 3.4e-06 26.2 0.0 0.0011 18.0 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.17 AMK75332.1 - 0.00038 20.6 1.7 0.00041 20.5 0.2 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 AMK75332.1 - 0.0022 17.0 0.1 0.029 13.3 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 AMK75332.1 - 0.0063 16.8 0.2 0.17 12.2 0.2 2.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 AMK75332.1 - 0.0068 15.8 0.1 6.3 6.2 0.0 3.2 3 0 0 3 3 3 1 Bacterial TniB protein T2SSE PF00437.20 AMK75332.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 AMK75332.1 - 0.016 15.0 0.1 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase FHIPEP PF00771.20 AMK75332.1 - 0.018 13.6 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 FHIPEP family Zeta_toxin PF06414.12 AMK75332.1 - 0.09 12.0 0.5 9.5 5.4 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin Pyr_redox_2 PF07992.14 AMK75333.1 - 8.8e-51 172.9 0.5 1e-50 172.6 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK75333.1 - 2.4e-18 66.5 0.1 3.8e-15 55.9 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK75333.1 - 1.2e-16 61.0 0.7 8.6e-16 58.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK75333.1 - 4.2e-06 26.1 5.7 0.0059 15.7 0.1 3.6 2 1 2 4 4 4 2 FAD binding domain GIDA PF01134.22 AMK75333.1 - 0.00011 21.5 0.8 0.085 11.9 0.0 3.6 4 0 0 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.14 AMK75333.1 - 0.00017 20.4 1.0 0.83 8.3 0.1 4.4 4 1 1 5 5 5 1 HI0933-like protein FAD_oxidored PF12831.7 AMK75333.1 - 0.0019 17.6 0.1 0.0044 16.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AMK75333.1 - 0.0049 17.3 0.0 0.057 13.9 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 AMK75333.1 - 0.024 14.2 0.8 19 4.7 0.1 3.3 3 1 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 AMK75333.1 - 0.025 14.6 0.5 1.1 9.3 0.0 3.0 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 AMK75333.1 - 0.039 12.4 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 AMK75333.1 - 0.045 13.0 0.2 3.8 6.7 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.6 AMK75333.1 - 0.079 12.1 0.0 3.8 6.6 0.0 2.3 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AMK75333.1 - 0.086 13.1 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ICMT PF04140.14 AMK75334.1 - 1.4e-20 73.5 0.5 2.6e-20 72.6 0.5 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 AMK75334.1 - 4.8e-17 62.3 0.7 4.8e-17 62.3 0.7 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.11 AMK75334.1 - 0.0073 15.8 8.0 0.021 14.3 8.0 1.7 1 1 0 1 1 1 1 NnrU protein ABC_tran PF00005.27 AMK75335.1 - 1.1e-34 119.9 0.0 3.4e-34 118.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AMK75335.1 - 1.5e-07 31.6 0.7 0.00041 20.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK75335.1 - 1.3e-05 24.8 0.3 0.0011 18.5 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AMK75335.1 - 2.7e-05 24.6 0.5 6.1e-05 23.5 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AMK75335.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AMK75335.1 - 0.00041 20.0 0.1 0.00077 19.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AMK75335.1 - 0.00088 19.3 0.3 0.0015 18.6 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 AMK75335.1 - 0.0016 18.2 0.2 0.043 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AMK75335.1 - 0.0017 18.6 0.1 0.011 16.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 AMK75335.1 - 0.006 16.7 0.1 0.0097 16.0 0.1 1.3 1 0 0 1 1 1 1 Dynamin family Rad17 PF03215.15 AMK75335.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain cobW PF02492.19 AMK75335.1 - 0.013 15.1 0.1 0.042 13.4 0.1 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AMK75335.1 - 0.013 16.0 0.1 0.023 15.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 AMK75335.1 - 0.039 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 AMK75335.1 - 0.044 13.9 0.3 0.22 11.6 0.3 2.0 1 1 0 1 1 1 0 AAA domain DUF3987 PF13148.6 AMK75335.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_28 PF13521.6 AMK75335.1 - 0.12 12.7 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 AMK75335.1 - 0.13 11.1 0.0 1.2 7.8 0.0 2.1 2 1 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 AMK75335.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsX PF02687.21 AMK75336.1 - 9.1e-21 74.1 21.0 1.3e-14 54.4 5.1 4.7 6 0 0 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 AMK75336.1 - 3.3e-08 34.1 0.2 0.00091 19.6 0.0 2.7 2 0 0 2 2 2 2 MacB-like periplasmic core domain Phosphonate-bd PF12974.7 AMK75337.1 - 3.9e-41 141.3 0.0 6.5e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PAS_3 PF08447.12 AMK75337.1 - 4.6e-24 84.5 0.1 1.4e-23 83.0 0.1 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AMK75337.1 - 2.5e-22 79.5 0.0 4.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK75337.1 - 1.2e-12 47.7 0.2 3.6e-12 46.1 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SBP_bac_3 PF00497.20 AMK75337.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 HATPase_c_5 PF14501.6 AMK75337.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AMK75337.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NMT1 PF09084.11 AMK75337.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 NMT1/THI5 like HATPase_c_2 PF13581.6 AMK75337.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS_9 PF13426.7 AMK75337.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 PAS domain CHASE PF03924.13 AMK75338.1 - 6.2e-57 192.6 0.1 2.6e-56 190.6 0.0 2.1 2 0 0 2 2 2 1 CHASE domain HATPase_c PF02518.26 AMK75338.1 - 3.5e-17 62.9 0.0 7e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AMK75338.1 - 1.1e-16 60.9 0.5 3.3e-16 59.3 0.5 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AMK75338.1 - 1.2e-09 38.4 0.0 2.9e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK75338.1 - 3e-09 36.9 0.0 5.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK75338.1 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK75338.1 - 0.022 14.8 0.0 0.07 13.2 0.0 1.9 1 0 0 1 1 1 0 PAS domain HisKA PF00512.25 AMK75338.1 - 0.79 9.8 3.0 0.57 10.3 0.4 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AMK75339.1 - 8.6e-22 77.4 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GGDEF PF00990.21 AMK75340.1 - 1.4e-47 161.4 0.1 2.3e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AMK75340.1 - 1.4e-27 95.8 1.2 2.8e-18 66.0 0.4 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AMK75340.1 - 2.8e-20 72.5 0.0 5.3e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain Response_reg PF00072.24 AMK75340.1 - 7.7e-20 71.1 0.0 1.8e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AMK75340.1 - 6.8e-14 51.8 0.1 6.1e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AMK75340.1 - 9.7e-12 45.1 0.1 3.5e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AMK75340.1 - 5.6e-08 32.6 0.1 4.8e-05 23.3 0.0 3.5 3 0 0 3 3 3 1 PAS domain GGDEF_2 PF17853.1 AMK75340.1 - 0.017 15.4 0.1 0.088 13.1 0.0 2.3 2 0 0 2 2 2 0 GGDEF-like domain PAS_11 PF14598.6 AMK75340.1 - 0.042 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain RRM_1 PF00076.22 AMK75341.1 - 0.0057 16.5 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amino_oxidase PF01593.24 AMK75342.1 - 4.5e-26 92.2 0.0 3.9e-25 89.1 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AMK75342.1 - 3.6e-13 49.5 0.0 1e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK75342.1 - 4e-11 43.1 0.2 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AMK75342.1 - 5.7e-11 42.2 0.1 4.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK75342.1 - 1.1e-09 37.9 1.8 6.1e-08 32.2 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AMK75342.1 - 1.2e-09 37.4 2.9 1.3e-06 27.5 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 AMK75342.1 - 7.6e-09 36.0 2.5 0.00049 20.6 0.3 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AMK75342.1 - 4.8e-08 32.8 0.1 4.4e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 AMK75342.1 - 9.3e-06 25.0 2.8 5.5e-05 22.4 0.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AMK75342.1 - 0.00044 19.6 0.5 0.00071 18.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 AMK75342.1 - 0.00063 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FMO-like PF00743.19 AMK75342.1 - 0.0051 15.3 0.0 0.0073 14.8 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 AMK75342.1 - 0.0058 15.9 0.4 0.051 12.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AMK75342.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 AMK75342.1 - 0.011 14.8 0.4 0.31 10.0 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.18 AMK75342.1 - 0.014 13.9 0.6 0.03 12.8 0.1 1.6 2 0 0 2 2 2 0 GDP dissociation inhibitor 3HCDH_N PF02737.18 AMK75342.1 - 0.015 15.2 0.3 0.025 14.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 AMK75342.1 - 0.018 15.1 0.2 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AMK75342.1 - 0.06 12.9 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MCRA PF06100.11 AMK75342.1 - 0.061 12.1 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 MCRA family Trp_halogenase PF04820.14 AMK75342.1 - 0.072 11.9 2.0 3.3 6.5 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase IGR PF09597.10 AMK75342.1 - 0.073 13.2 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 IGR protein motif Aldedh PF00171.22 AMK75343.1 - 4.1e-128 427.8 0.0 4.9e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 AMK75344.1 - 2.3e-31 109.6 0.0 2.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AMK75344.1 - 1e-12 48.1 0.1 2.4e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK75344.1 - 7e-09 35.7 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK75344.1 - 5.1e-08 32.4 1.6 0.00085 18.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 AMK75344.1 - 1.8e-07 30.8 0.0 2.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AMK75344.1 - 2.6e-07 29.7 0.5 0.0007 18.4 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 AMK75344.1 - 5e-06 25.9 0.1 5.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 AMK75344.1 - 0.00012 21.4 0.0 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AMK75344.1 - 0.00018 21.0 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 AMK75344.1 - 0.00038 21.0 1.3 0.47 11.1 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AMK75344.1 - 0.0032 16.6 1.1 1.1 8.2 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AMK75344.1 - 0.007 15.7 0.8 0.019 14.3 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 AMK75344.1 - 0.02 13.5 0.0 0.48 8.9 0.0 2.2 2 0 0 2 2 2 0 GDP dissociation inhibitor NAD_binding_9 PF13454.6 AMK75344.1 - 0.13 12.3 1.1 1 9.4 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding RIO1 PF01163.22 AMK75345.1 - 2.2e-43 148.1 0.0 3.3e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 AMK75345.1 - 3.6e-05 23.8 0.4 0.004 17.1 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 AMK75345.1 - 0.0042 16.5 0.1 0.27 10.6 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 AMK75345.1 - 0.039 13.5 0.0 0.057 12.9 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Ald_Xan_dh_C2 PF02738.18 AMK75346.1 - 4.4e-69 233.4 0.1 1.6e-34 119.3 0.0 3.1 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 AMK75346.1 - 0.002 18.4 0.0 0.0093 16.3 0.0 2.1 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DNA_binding_1 PF01035.20 AMK75346.1 - 0.022 14.9 0.7 0.14 12.3 0.0 2.5 2 1 1 3 3 3 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Fer2_2 PF01799.20 AMK75347.1 - 2.5e-27 94.7 0.2 2.5e-27 94.7 0.2 1.6 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AMK75347.1 - 6.7e-09 35.6 0.1 6.7e-09 35.6 0.1 2.1 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AMK75347.1 - 5.9e-07 29.5 1.0 7.5e-07 29.1 0.2 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AMK75347.1 - 0.0036 17.3 1.4 0.01 15.9 0.7 2.2 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AMK75347.1 - 3.3 7.6 10.3 0.21 11.4 4.7 1.9 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B ROK PF00480.20 AMK75348.1 - 3.1e-20 72.8 3.3 8.4e-18 64.8 1.0 2.7 1 1 1 2 2 2 2 ROK family DUF393 PF04134.12 AMK75349.1 - 2.1e-21 77.4 0.0 2.7e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 SOUL PF04832.12 AMK75350.1 - 1.3e-46 158.8 0.0 2.3e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein GyrI-like PF06445.15 AMK75350.1 - 0.023 15.0 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 GyrI-like small molecule binding domain CbiX PF01903.17 AMK75351.1 - 9.8e-28 96.6 0.3 1.1e-27 96.4 0.3 1.0 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 AMK75351.1 - 5.6e-06 25.9 0.0 6.5e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) DEAD PF00270.29 AMK75352.1 - 2.6e-49 167.4 0.5 1.9e-48 164.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK75352.1 - 3.3e-28 98.2 0.0 9.3e-28 96.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 AMK75352.1 - 1.2e-07 32.2 2.6 0.0041 17.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain ResIII PF04851.15 AMK75352.1 - 2.6e-07 30.8 0.0 1.8e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 AMK75352.1 - 0.0012 18.5 0.8 0.063 12.8 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 AMK75352.1 - 0.0017 18.6 1.1 0.011 16.0 0.5 2.5 2 1 0 2 2 2 1 AAA domain PD40 PF07676.12 AMK75353.1 - 0.042 13.8 0.3 1.9 8.5 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1624 PF07786.12 AMK75354.1 - 1.2e-18 67.6 11.3 9.5e-18 64.6 7.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1624) Acyl_transf_3 PF01757.22 AMK75354.1 - 2.5e-05 23.5 29.3 0.0028 16.8 29.2 2.7 1 1 0 1 1 1 1 Acyltransferase family OpgC_C PF10129.9 AMK75354.1 - 9.4e-05 21.4 13.1 0.013 14.4 2.3 2.9 1 1 0 2 2 2 2 OpgC protein TraX PF05857.11 AMK75354.1 - 0.032 14.3 0.1 0.032 14.3 0.1 2.9 2 1 1 3 3 3 0 TraX protein DUF5504 PF17608.2 AMK75354.1 - 1.1 9.4 5.1 4.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5504) ROF PF07073.12 AMK75355.1 - 1.6e-25 89.0 0.3 1.8e-25 88.9 0.3 1.0 1 0 0 1 1 1 1 Modulator of Rho-dependent transcription termination (ROF) TAL_FSA PF00923.19 AMK75356.1 - 8.8e-36 123.7 0.0 3.6e-34 118.4 0.0 2.0 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase YkuD PF03734.14 AMK75357.1 - 2.4e-24 86.4 0.0 3.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 AMK75357.1 - 6.2e-08 32.7 1.1 1.5e-07 31.5 0.1 2.2 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Peptidase_M15_2 PF05951.13 AMK75358.1 - 4.7e-53 179.0 0.0 8.9e-53 178.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 AMK75358.1 - 4e-11 43.0 0.1 1.1e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M15 MSA_2 PF00985.17 AMK75358.1 - 0.053 13.9 3.2 0.097 13.0 3.2 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF3422 PF11902.8 AMK75359.1 - 1.6e-159 531.5 1.5 1.8e-159 531.4 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) SPOB_a PF14689.6 AMK75360.1 - 0.0018 17.9 0.9 0.022 14.5 0.2 2.1 2 0 0 2 2 2 2 Sensor_kinase_SpoOB-type, alpha-helical domain HTH_Tnp_1 PF01527.20 AMK75361.1 - 1.1e-06 28.8 0.1 1.3e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AMK75361.1 - 0.00081 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Com_YlbF PF06133.11 AMK75361.1 - 0.016 15.8 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA HTH_Tnp_ISL3 PF13542.6 AMK75361.1 - 0.099 12.1 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.26 AMK75362.1 - 1.6e-20 73.5 0.3 5.7e-20 71.7 0.2 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 AMK75362.1 - 4.4e-18 64.8 0.3 1.4e-17 63.2 0.1 2.0 3 0 0 3 3 3 1 Integrase core domain HTH_21 PF13276.6 AMK75362.1 - 2.5e-10 40.4 0.3 5.2e-10 39.3 0.3 1.5 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_IS240 PF13610.6 AMK75362.1 - 8e-08 32.6 0.1 1.1e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 DDE domain rve_2 PF13333.6 AMK75362.1 - 4.1e-07 30.1 0.5 1.1e-06 28.7 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_3 PF01381.22 AMK75363.1 - 4.8e-07 29.7 0.0 8.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AMK75363.1 - 7.6e-05 22.7 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AMK75363.1 - 0.00022 21.5 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AMK75363.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 1 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MqsA_antitoxin PF15731.5 AMK75363.1 - 0.0031 17.6 0.0 0.0036 17.4 0.0 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_23 PF13384.6 AMK75363.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 AMK75363.1 - 0.047 13.4 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 helix-turn-helix, Psq domain RelE PF06296.12 AMK75364.1 - 5e-09 36.3 0.2 1.3e-08 35.0 0.1 1.5 1 1 1 2 2 2 1 RelE toxin of RelE / RelB toxin-antitoxin system EutC PF05985.11 AMK75365.1 - 3.1e-82 275.4 0.1 3.5e-82 275.2 0.1 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) EutB PF06751.11 AMK75366.1 - 8.8e-217 720.1 0.0 1e-216 719.9 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) LacAB_rpiB PF02502.18 AMK75366.1 - 0.0034 17.4 0.1 0.0066 16.4 0.1 1.4 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Amino_oxidase PF01593.24 AMK75367.1 - 4.9e-43 148.1 0.0 5.7e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AMK75367.1 - 1.7e-14 53.8 0.1 6.6e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK75367.1 - 1.9e-08 34.3 0.1 5.7e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK75367.1 - 2.7e-07 30.0 0.4 5e-07 29.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AMK75367.1 - 9.6e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AMK75367.1 - 5.3e-06 25.8 0.0 8.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 AMK75367.1 - 1.4e-05 24.5 0.4 7e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AMK75367.1 - 0.00076 18.3 0.1 0.0014 17.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 AMK75367.1 - 0.0008 18.8 1.0 0.0042 16.4 0.1 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AMK75367.1 - 0.0008 18.7 0.1 0.0034 16.7 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK75367.1 - 0.0022 18.5 0.6 0.0077 16.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AMK75367.1 - 0.0027 17.0 0.4 0.14 11.5 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AMK75367.1 - 0.0086 15.2 0.3 0.015 14.4 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AMK75367.1 - 0.012 15.6 0.3 2.2 8.3 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 AMK75367.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein MCRA PF06100.11 AMK75367.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 MCRA family HTH_Tnp_1 PF01527.20 AMK75368.1 - 2.9e-07 30.7 0.1 3.4e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AMK75368.1 - 0.00025 21.1 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AMK75368.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 IstB_IS21 PF01695.17 AMK75369.1 - 7.4e-58 195.2 0.1 9.9e-58 194.8 0.1 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK75369.1 - 6e-10 39.3 0.0 9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK75369.1 - 2.2e-05 24.0 0.1 3.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AMK75369.1 - 0.004 17.6 0.0 0.0062 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AMK75369.1 - 0.0065 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AMK75369.1 - 0.01 15.8 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 AMK75369.1 - 0.018 14.1 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 AMK75369.1 - 0.026 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 AMK75369.1 - 0.03 14.0 0.2 0.061 13.0 0.2 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 AMK75369.1 - 0.04 14.2 0.6 0.27 11.5 0.3 2.1 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 AMK75369.1 - 0.051 13.5 2.0 0.87 9.5 0.0 2.6 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 AMK75369.1 - 0.067 13.2 0.5 0.24 11.4 0.3 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AMK75369.1 - 0.069 12.7 0.1 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 AMK75369.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AMK75369.1 - 0.083 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 AMK75369.1 - 0.095 12.7 0.4 0.24 11.4 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AMK75369.1 - 0.11 12.8 1.9 0.21 11.9 0.9 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 AMK75369.1 - 0.14 11.9 0.5 0.4 10.4 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AMK75369.1 - 0.16 12.4 0.6 0.37 11.2 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain rve PF00665.26 AMK75370.1 - 1.2e-14 54.5 0.1 2.7e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_5 PF01022.20 AMK75370.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AMK75370.1 - 0.00073 19.4 0.1 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 AMK75370.1 - 0.0021 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 AMK75370.1 - 0.0044 16.8 0.1 0.031 14.1 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AMK75370.1 - 0.0055 16.7 0.4 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 AMK75370.1 - 0.01 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 AMK75370.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 AMK75370.1 - 0.014 15.1 0.0 0.35 10.7 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain HTH_24 PF13412.6 AMK75370.1 - 0.036 13.6 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 AMK75370.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AMK75370.1 - 0.081 13.1 0.3 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 AMK75370.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK75370.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_7 PF02796.15 AMK75370.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 AMK75370.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_41 PF14502.6 AMK75370.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.13 AMK75370.1 - 0.18 12.1 0.0 0.52 10.6 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain SpoIIAA-like PF11964.8 AMK75371.1 - 0.0091 17.0 0.0 0.012 16.6 0.0 1.1 1 0 0 1 1 1 1 SpoIIAA-like Response_reg PF00072.24 AMK75372.1 - 1.2e-23 83.4 0.0 1.3e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HTH_Tnp_1 PF01527.20 AMK75374.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK75374.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK75374.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75374.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK75374.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK75374.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK75375.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK75375.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK75375.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK75375.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK75375.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK75375.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK75375.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 Phage_integrase PF00589.22 AMK75376.1 - 4.2e-15 56.0 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 AMK75376.1 - 4.4e-14 52.6 0.2 2.1e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 Arm DNA-binding domain HTH_3 PF01381.22 AMK75377.1 - 1.3e-09 38.0 0.8 0.00022 21.2 0.0 2.9 2 1 0 2 2 2 2 Helix-turn-helix HTH_19 PF12844.7 AMK75377.1 - 3.3e-09 36.6 1.0 0.00014 21.8 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_31 PF13560.6 AMK75377.1 - 4.7e-05 23.7 0.0 0.053 13.9 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_25 PF13413.6 AMK75377.1 - 0.0022 17.8 0.2 0.032 14.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain LacI PF00356.21 AMK75377.1 - 0.018 14.8 0.0 4.3 7.2 0.0 2.6 1 1 1 2 2 2 0 Bacterial regulatory proteins, lacI family RWP-RK PF02042.15 AMK75377.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain TetR_C_2 PF08361.11 AMK75377.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region HTH_17 PF12728.7 AMK75378.1 - 0.00029 21.0 0.0 0.00038 20.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.6 AMK75379.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AMK75379.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 MarR family DnaB_C PF03796.15 AMK75381.1 - 1e-69 234.8 0.0 1.4e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 AMK75381.1 - 8.4e-12 45.1 0.8 1.5e-11 44.3 0.3 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 AMK75381.1 - 1.9e-06 27.4 0.1 5.2e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 KaiC ArsA_ATPase PF02374.15 AMK75381.1 - 0.028 13.6 0.3 0.054 12.7 0.3 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AIRS PF00586.24 AMK75381.1 - 0.03 15.0 0.2 11 6.8 0.0 3.4 3 1 0 3 3 3 0 AIR synthase related protein, N-terminal domain ParA PF10609.9 AMK75381.1 - 0.15 11.4 1.1 0.27 10.7 0.4 1.6 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase DivIVA PF05103.13 AMK75383.1 - 0.018 15.1 0.9 3.6 7.7 0.3 2.2 1 1 1 2 2 2 0 DivIVA protein TPR_MalT PF17874.1 AMK75383.1 - 0.053 12.9 0.6 0.13 11.6 0.6 1.6 1 1 0 1 1 1 0 MalT-like TPR region HlyD_2 PF12700.7 AMK75383.1 - 0.053 12.3 2.1 0.081 11.6 2.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein HTH_31 PF13560.6 AMK75386.1 - 7.5e-05 23.0 0.2 0.0004 20.7 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Phage_GPO PF05929.11 AMK75386.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase HTH_19 PF12844.7 AMK75386.1 - 0.027 14.5 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK75387.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.6 AMK75389.1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain Bro-N PF02498.17 AMK75390.1 - 3e-21 75.9 0.0 3.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 BRO family, N-terminal domain SMBP PF16785.5 AMK75391.1 - 2.7e-26 92.0 20.4 2.9e-26 91.8 20.4 1.0 1 0 0 1 1 1 1 Small metal-binding protein LPAM_1 PF08139.12 AMK75391.1 - 0.12 12.9 1.6 0.22 12.1 1.6 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SNARE PF05739.19 AMK75391.1 - 0.83 9.7 0.0 0.83 9.7 0.0 4.3 4 1 1 5 5 5 0 SNARE domain Phage_AlpA PF05930.12 AMK75392.1 - 6.4e-07 29.1 0.0 9.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) Phage_pRha PF09669.10 AMK75393.1 - 2.7e-13 50.3 0.0 6e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) DUF2288 PF10052.9 AMK75394.1 - 0.036 14.1 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) DUF4258 PF14076.6 AMK75395.1 - 1.2e-11 44.8 0.1 1.7e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) HTH_3 PF01381.22 AMK75396.1 - 2.4e-05 24.3 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AMK75396.1 - 0.00037 20.4 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AMK75396.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 AMK75396.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA RdgC PF04381.12 AMK75397.1 - 0.046 13.0 0.1 0.054 12.8 0.1 1.0 1 0 0 1 1 1 0 Putative exonuclease, RdgC DNase_NucA_NucB PF14040.6 AMK75398.1 - 7.1e-14 52.2 0.0 8.7e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Phage_integrase PF00589.22 AMK75402.1 - 4.7e-32 111.1 0.6 9.7e-32 110.1 0.1 1.8 2 1 0 2 2 2 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AMK75402.1 - 0.0059 16.9 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 Phage integrase SAM-like domain KilA-N PF04383.13 AMK75403.1 - 1.5e-18 66.6 0.1 2.4e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 KilA-N domain HTH_17 PF12728.7 AMK75404.1 - 4.2e-12 46.1 0.0 5.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75404.1 - 0.00053 19.7 0.1 0.0015 18.2 0.0 1.7 1 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 AMK75404.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase YCII PF03795.14 AMK75405.1 - 7.8e-21 74.3 0.0 9.6e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Sulfate_transp PF00916.20 AMK75406.1 - 3.3e-85 286.2 22.5 4.3e-85 285.8 22.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 AMK75406.1 - 8.3e-15 54.5 0.0 1.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AMK75406.1 - 0.00025 21.3 0.1 0.00061 20.1 0.1 1.7 1 0 0 1 1 1 1 STAS domain TPMT PF05724.11 AMK75407.1 - 7.5e-75 251.3 0.0 8.2e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 AMK75407.1 - 0.089 13.5 0.0 0.37 11.5 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain TauE PF01925.19 AMK75408.1 - 3.4e-25 89.0 18.9 4.2e-25 88.8 18.9 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE MASE2 PF05230.11 AMK75408.1 - 0.25 11.4 5.5 0.085 12.9 2.3 1.8 1 1 1 2 2 2 0 MASE2 domain GNVR PF13807.6 AMK75408.1 - 0.51 10.3 0.1 0.51 10.3 0.1 2.4 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase CPP1-like PF11833.8 AMK75408.1 - 1.8 8.1 4.6 1 9.0 2.7 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sigma54_activat PF00158.26 AMK75409.1 - 2.6e-69 232.3 0.0 3.5e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK75409.1 - 2.3e-21 76.4 0.0 4.9e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK75409.1 - 8.7e-09 35.0 0.2 1.8e-08 34.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK75409.1 - 9.5e-08 32.1 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PAS_9 PF13426.7 AMK75409.1 - 2.4e-07 31.0 0.0 5.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK75409.1 - 7.6e-07 29.1 0.0 4e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 PAS fold AAA PF00004.29 AMK75409.1 - 8.1e-06 26.3 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PAS_4 PF08448.10 AMK75409.1 - 3.7e-05 23.9 0.0 0.00038 20.7 0.0 2.6 2 1 0 2 2 2 1 PAS fold Mg_chelatase PF01078.21 AMK75409.1 - 0.00026 20.5 0.1 0.083 12.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AMK75409.1 - 0.0025 17.1 0.0 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain UBA PF00627.31 AMK75409.1 - 0.0047 16.8 0.2 0.0093 15.9 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain AAA_16 PF13191.6 AMK75409.1 - 0.015 15.7 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AMK75409.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK75409.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 AMK75409.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_PrkA PF08298.11 AMK75409.1 - 0.031 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain PAS_8 PF13188.7 AMK75409.1 - 0.1 12.6 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 1 0 PAS domain DHDPS PF00701.22 AMK75409.1 - 0.15 10.8 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Lactamase_B PF00753.27 AMK75410.1 - 7.5e-21 75.0 1.6 1.3e-19 71.0 1.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK75410.1 - 0.045 13.2 0.6 0.069 12.7 0.6 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Ecotin PF03974.13 AMK75410.1 - 0.2 11.6 0.0 0.49 10.4 0.0 1.6 2 0 0 2 2 2 0 Ecotin TauE PF01925.19 AMK75411.1 - 3.4e-49 167.6 45.6 3.4e-49 167.6 45.6 1.4 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE PsiE PF06146.12 AMK75412.1 - 2.1e-18 66.5 5.7 3.8e-18 65.6 5.7 1.4 1 0 0 1 1 1 1 Phosphate-starvation-inducible E Cu-oxidase_3 PF07732.15 AMK75413.1 - 7.3e-24 84.1 0.1 2.9e-22 78.9 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AMK75413.1 - 9.6e-19 67.5 4.7 1.1e-18 67.3 0.5 2.8 2 1 0 2 2 2 1 Multicopper oxidase DUF3601 PF12208.8 AMK75413.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) DsbD_2 PF13386.6 AMK75414.1 - 2.7e-41 141.7 23.3 2.7e-41 141.7 23.3 1.9 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region DsbD PF02683.15 AMK75414.1 - 2.9e-09 37.1 11.9 2.9e-09 37.1 11.9 1.9 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region HMA PF00403.26 AMK75414.1 - 6.3e-08 33.0 0.3 9.5e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain HemY_N PF07219.13 AMK75414.1 - 0.49 10.6 6.5 0.12 12.6 0.8 2.8 3 0 0 3 3 3 0 HemY protein N-terminus Cyt_bd_oxida_I PF01654.17 AMK75416.1 - 9.9e-176 584.4 23.8 1.2e-175 584.1 23.8 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cyt_bd_oxida_II PF02322.15 AMK75417.1 - 1.8e-94 316.5 33.2 2.1e-94 316.3 33.2 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF4637 PF15470.6 AMK75417.1 - 0.5 10.1 0.8 0.79 9.4 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) TrbC PF04956.13 AMK75417.1 - 3.5 7.9 12.5 0.53 10.5 4.3 3.0 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF2892 PF11127.8 AMK75418.1 - 9.6e-18 64.0 0.2 1.2e-17 63.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) NAF PF03822.14 AMK75418.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 NAF domain Pyr_redox_2 PF07992.14 AMK75419.1 - 3.2e-17 62.7 0.0 7.1e-17 61.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AMK75419.1 - 0.0017 18.4 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 AMK75419.1 - 0.016 15.8 0.5 1.5 9.4 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK75419.1 - 0.025 14.2 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 AMK75419.1 - 0.063 12.4 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 AMK75419.1 - 0.063 12.5 1.9 1.7 7.8 0.4 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AMK75419.1 - 0.092 11.8 0.1 0.66 9.0 0.1 2.2 2 1 1 3 3 3 0 Lycopene cyclase protein OEP PF02321.18 AMK75420.1 - 1.4e-61 207.6 36.1 6.8e-32 110.8 12.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Flagellin_C PF00700.21 AMK75420.1 - 0.14 12.6 10.5 1 9.7 0.0 4.2 3 2 0 3 3 3 0 Bacterial flagellin C-terminal helical region HlyD_D23 PF16576.5 AMK75421.1 - 2.9e-19 69.1 1.6 4.4e-19 68.5 1.6 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK75421.1 - 3.7e-13 50.1 0.1 5.3e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK75421.1 - 4.2e-11 42.5 1.8 4.2e-11 42.5 1.8 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK75421.1 - 0.0079 16.0 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme PYNP_C PF07831.13 AMK75421.1 - 0.011 15.4 0.0 0.091 12.4 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Peptidase_M23 PF01551.22 AMK75421.1 - 0.077 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 AMK75421.1 - 0.087 12.6 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HlyD PF00529.20 AMK75421.1 - 1.7 8.6 6.3 2.7 7.9 6.3 1.7 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS ACR_tran PF00873.19 AMK75422.1 - 4.3e-156 521.3 20.8 4.2e-154 514.7 20.8 2.0 1 1 0 1 1 1 1 AcrB/AcrD/AcrF family DUF4081 PF13312.6 AMK75422.1 - 0.13 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) DUF2368 PF10166.9 AMK75422.1 - 0.17 11.5 0.1 0.73 9.5 0.1 2.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) EcKinase PF02958.20 AMK75423.1 - 3.8e-19 69.1 0.0 1e-18 67.7 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 AMK75423.1 - 2.9e-17 63.4 1.0 3.9e-17 63.0 1.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 AMK75423.1 - 2.1e-10 40.1 0.0 6.5e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pro_CA PF00484.19 AMK75424.1 - 8.2e-11 42.4 0.0 1.6e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Cupin_2 PF07883.11 AMK75425.1 - 4.2e-07 29.6 0.3 5.8e-07 29.1 0.3 1.2 1 0 0 1 1 1 1 Cupin domain DUF4437 PF14499.6 AMK75425.1 - 0.0032 16.6 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_7 PF12973.7 AMK75425.1 - 0.05 13.5 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain HTH_Crp_2 PF13545.6 AMK75426.1 - 7.9e-09 35.4 0.1 1.8e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AMK75426.1 - 1.7e-08 34.4 0.0 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Crp PF00325.20 AMK75426.1 - 0.00014 21.4 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_29 PF13551.6 AMK75426.1 - 0.0031 17.5 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix MarR_2 PF12802.7 AMK75426.1 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AMK75426.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 AMK75426.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_38 PF13936.6 AMK75426.1 - 0.1 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 AMK75426.1 - 0.19 11.9 0.1 0.46 10.6 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain DUF4229 PF14012.6 AMK75427.1 - 0.027 14.5 0.1 0.031 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF2079 PF09852.9 AMK75427.1 - 0.048 12.5 1.4 0.047 12.5 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) RseC_MucC PF04246.12 AMK75427.1 - 0.05 13.5 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF3100 PF11299.8 AMK75427.1 - 0.06 12.8 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) TM_helix PF05552.12 AMK75427.1 - 0.23 11.5 3.9 0.33 11.0 3.9 1.2 1 0 0 1 1 1 0 Conserved TM helix LapA_dom PF06305.11 AMK75427.1 - 0.77 9.6 5.1 0.39 10.6 3.2 1.5 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain ydhR PF08803.11 AMK75428.1 - 7.5e-07 29.0 0.0 8.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR adh_short PF00106.25 AMK75429.1 - 4.3e-28 98.1 0.1 6e-28 97.6 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AMK75429.1 - 2.8e-27 95.8 1.3 3.4e-27 95.5 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 AMK75429.1 - 0.023 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF938 PF06080.12 AMK75430.1 - 2e-57 194.3 0.0 2.3e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 AMK75430.1 - 5.1e-06 27.1 0.0 8.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75430.1 - 2.7e-05 24.8 0.0 4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75430.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75430.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75430.1 - 0.12 13.1 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sigma54_activat PF00158.26 AMK75431.1 - 2.5e-69 232.3 0.1 3.9e-69 231.7 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK75431.1 - 1.3e-26 93.4 0.0 5.6e-26 91.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK75431.1 - 2e-08 33.8 0.0 5.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK75431.1 - 2.2e-07 31.0 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK75431.1 - 2.4e-06 28.0 0.0 5.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 AMK75431.1 - 4.5e-06 26.9 0.0 8.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) MetOD1 PF18546.1 AMK75431.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Metanogen output domain 1 Mg_chelatase PF01078.21 AMK75431.1 - 0.0015 17.9 0.2 0.87 8.9 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI HTH_50 PF18024.1 AMK75431.1 - 0.0024 17.5 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_3 PF07726.11 AMK75431.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_28 PF13518.6 AMK75431.1 - 0.066 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AMK75431.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4405 PF14358.6 AMK75432.1 - 5.5e-14 52.5 9.5 1.1e-13 51.5 9.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) PSCyt1 PF07635.11 AMK75432.1 - 2.7e-08 34.3 0.0 5.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Planctomycete cytochrome C Cytochrome_CBB3 PF13442.6 AMK75432.1 - 0.0016 18.7 0.0 0.0044 17.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Ni_hydr_CYTB PF01292.20 AMK75432.1 - 0.0045 16.6 5.0 0.0045 16.6 5.0 2.0 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_C PF00034.21 AMK75432.1 - 0.013 16.7 0.0 0.026 15.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c Haem_bd PF14376.6 AMK75432.1 - 0.18 11.8 0.2 0.94 9.4 0.0 2.0 2 0 0 2 2 2 0 Haem-binding domain Arm-DNA-bind_3 PF13356.6 AMK75434.1 - 3.8e-18 65.6 0.0 1e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 AMK75434.1 - 8e-07 29.0 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_integr_3 PF16795.5 AMK75434.1 - 0.0096 15.8 0.2 0.061 13.2 0.0 2.1 2 0 0 2 2 2 1 Archaeal phage integrase DUF3850 PF12961.7 AMK75434.1 - 0.048 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) HTH_36 PF13730.6 AMK75434.1 - 0.14 12.1 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 AMK75435.1 - 9.1e-36 122.8 0.0 1.3e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 AMK75435.1 - 6.1e-19 67.4 0.1 1.7e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 AMK75435.1 - 2.8e-09 36.5 0.0 7.7e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AMK75435.1 - 4.7e-09 36.2 0.0 2.5e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 AMK75435.1 - 6.2e-09 36.3 0.0 1.5e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AMK75435.1 - 6.1e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix DDE_1 PF03184.19 AMK75435.1 - 4.7e-05 23.1 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 AMK75435.1 - 5.2e-05 22.6 0.6 0.0002 20.7 0.6 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 LZ_Tnp_IS481 PF13011.6 AMK75435.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_IS630 PF01710.16 AMK75435.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_Tnp_1 PF01527.20 AMK75435.1 - 0.033 14.5 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_40 PF14493.6 AMK75435.1 - 0.083 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Fic PF02661.18 AMK75436.1 - 1.4e-07 32.3 0.0 3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family SLT PF01464.20 AMK75438.1 - 1.6e-09 37.4 0.1 4.2e-09 36.1 0.0 1.7 2 1 0 2 2 2 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AMK75438.1 - 0.0053 17.2 0.0 0.025 15.1 0.0 1.9 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase FlhD PF05247.13 AMK75439.1 - 2.9e-13 49.9 0.1 3.3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF2857 PF11198.8 AMK75439.1 - 0.043 13.6 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) UPF0175 PF03683.13 AMK75440.1 - 1.4e-13 50.3 0.0 2.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) PhdYeFM_antitox PF02604.19 AMK75440.1 - 8.1e-07 28.8 0.1 1.2e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF3368 PF11848.8 AMK75441.1 - 2.8e-12 46.2 0.0 5.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3368) DUF2070 PF09843.9 AMK75442.1 - 0.7 8.1 8.6 0.8 7.9 8.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TraG_N PF07916.11 AMK75443.1 - 4e-98 329.3 19.9 4e-98 329.3 19.9 3.6 3 1 1 4 4 4 1 TraG-like protein, N-terminal region HrpF PF06266.12 AMK75443.1 - 0.77 10.1 5.4 6.9 7.1 0.4 3.8 3 0 0 3 3 3 0 HrpF protein TraH PF06122.11 AMK75444.1 - 1.9e-106 356.4 2.8 1.9e-106 356.4 2.8 1.5 2 0 0 2 2 2 1 Conjugative relaxosome accessory transposon protein SopA PF13981.6 AMK75444.1 - 0.028 14.9 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 SopA-like central domain Cbl_N3 PF02762.14 AMK75444.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Myb_Cef PF11831.8 AMK75444.1 - 0.22 11.1 0.4 0.33 10.5 0.4 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component TraF PF13728.6 AMK75445.1 - 4.9e-75 252.2 1.6 7.5e-75 251.6 1.6 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Trypan_PARP PF05887.11 AMK75445.1 - 0.0058 16.6 2.4 0.0099 15.9 2.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Thioredoxin_2 PF13098.6 AMK75445.1 - 0.02 15.3 0.1 0.07 13.6 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin-like domain AhpC-TSA PF00578.21 AMK75445.1 - 0.024 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family CK2S PF15011.6 AMK75446.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Casein Kinase 2 substrate HU-CCDC81_bac_2 PF18175.1 AMK75446.1 - 0.17 11.8 0.3 13 5.7 0.0 2.6 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Cep57_MT_bd PF06657.13 AMK75446.1 - 0.31 11.5 2.7 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 AMK75446.1 - 1.1 9.5 3.9 1.1 9.5 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HTH_Tnp_1 PF01527.20 AMK75448.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK75448.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK75448.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75448.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK75448.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK75448.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK75449.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK75449.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK75449.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK75449.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK75449.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK75449.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK75449.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 SoDot-IcmSS PF16848.5 AMK75450.1 - 0.066 13.2 2.3 0.11 12.5 2.3 1.6 1 1 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative Mt_ATP-synt_D PF05873.12 AMK75450.1 - 0.14 12.0 2.2 0.32 10.8 0.1 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TIR_2 PF13676.6 AMK75451.1 - 1e-24 87.4 0.6 1.8e-24 86.6 0.1 1.6 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 AMK75451.1 - 2.4e-07 30.8 0.5 4.3e-07 29.9 0.5 1.6 1 1 0 1 1 1 1 TIR domain Peptidase_M27 PF01742.17 AMK75451.1 - 0.0044 16.2 0.1 0.0053 15.9 0.1 1.1 1 0 0 1 1 1 1 Clostridial neurotoxin zinc protease TrfA PF07042.11 AMK75452.1 - 7.3e-16 58.0 0.0 9.1e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 TrfA protein RPA PF10134.9 AMK75452.1 - 0.00022 20.8 0.1 0.00079 19.0 0.0 2.0 3 1 0 3 3 3 1 Replication initiator protein A GxGYxYP_N PF16216.5 AMK75453.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Fip1 PF05182.13 AMK75453.1 - 0.22 11.0 1.1 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Fip1 motif TraI_2 PF07514.11 AMK75454.1 - 3.4e-96 322.0 0.9 4.7e-96 321.6 0.9 1.2 1 0 0 1 1 1 1 Putative helicase HD_6 PF18019.1 AMK75454.1 - 0.014 15.6 0.4 0.033 14.3 0.4 1.6 1 0 0 1 1 1 0 HD domain HD PF01966.22 AMK75454.1 - 0.019 15.2 0.1 0.072 13.3 0.1 1.9 1 1 0 1 1 1 0 HD domain DUF4489 PF14879.6 AMK75454.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) TrwB_AAD_bind PF10412.9 AMK75455.1 - 2.3e-15 56.4 0.0 6.9e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 AMK75455.1 - 1e-12 48.2 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG AAA_10 PF12846.7 AMK75455.1 - 7.2e-09 35.0 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 AMK75455.1 - 2.6e-05 24.4 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain T4SS-DNA_transf PF02534.14 AMK75455.1 - 3.5e-05 22.8 0.0 0.0014 17.5 0.0 2.1 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer DUF853 PF05872.12 AMK75455.1 - 0.00021 20.0 0.0 0.00035 19.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 AMK75455.1 - 0.00029 20.3 0.1 0.0064 15.9 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AMK75455.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 AMK75455.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF4400 PF14348.6 AMK75456.1 - 5.8e-23 81.5 1.0 6.9e-23 81.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) Fer2 PF00111.27 AMK75458.1 - 3.9e-15 55.6 1.3 6.9e-15 54.8 1.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 AMK75458.1 - 1.9e-13 51.0 0.0 4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AMK75458.1 - 2.1e-10 40.8 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.6 AMK75458.1 - 1.7e-05 24.8 0.2 4.1e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_9 PF08021.11 AMK75458.1 - 0.046 13.9 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Fer2_3 PF13085.6 AMK75458.1 - 0.05 13.6 0.4 0.093 12.7 0.4 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain LRRFIP PF09738.9 AMK75458.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 LRRFIP family NAD_binding_6 PF08030.12 AMK75458.1 - 0.14 12.3 0.0 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Bac_globin PF01152.21 AMK75459.1 - 1.5e-19 70.4 0.0 1.7e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 AMK75459.1 - 0.0022 17.9 0.1 0.0028 17.6 0.1 1.3 1 1 0 1 1 1 1 Protoglobin HTH_11 PF08279.12 AMK75460.1 - 2.6e-09 36.9 0.5 6.1e-09 35.7 0.5 1.6 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AMK75460.1 - 7.5e-08 32.2 0.2 2.1e-07 30.7 0.2 1.8 1 1 0 1 1 1 1 MarR family HTH_5 PF01022.20 AMK75460.1 - 4.3e-07 29.7 1.2 1.1e-06 28.3 1.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AMK75460.1 - 7e-07 28.7 0.1 1.5e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MetOD1 PF18546.1 AMK75460.1 - 9.5e-06 25.7 0.2 1.4e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Metanogen output domain 1 HTH_Mga PF08280.11 AMK75460.1 - 4.8e-05 23.3 0.5 0.00012 22.0 0.5 1.7 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_23 PF13384.6 AMK75460.1 - 8.2e-05 22.3 0.1 0.00017 21.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain ATC_hydrolase PF14196.6 AMK75460.1 - 8.3e-05 23.4 0.2 0.00016 22.5 0.2 1.4 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase HTH_20 PF12840.7 AMK75460.1 - 8.9e-05 22.5 2.4 0.00034 20.6 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain UPF0122 PF04297.14 AMK75460.1 - 0.00012 22.3 0.4 0.00035 20.8 0.0 1.9 2 1 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_Crp_2 PF13545.6 AMK75460.1 - 0.00017 21.5 0.2 0.00037 20.4 0.2 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AMK75460.1 - 0.00017 21.4 1.4 0.0002 21.2 0.3 1.7 2 0 0 2 2 1 1 MarR family HTH_34 PF13601.6 AMK75460.1 - 0.00023 21.3 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 AMK75460.1 - 0.00033 21.0 0.4 0.00065 20.0 0.4 1.5 1 0 0 1 1 1 1 Transcriptional regulator Sigma70_r4_2 PF08281.12 AMK75460.1 - 0.00051 19.7 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 AMK75460.1 - 0.00066 19.4 0.5 0.00066 19.4 0.5 1.7 2 0 0 2 2 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AMK75460.1 - 0.00085 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB GerE PF00196.19 AMK75460.1 - 0.0016 18.0 0.4 0.0036 16.8 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_DeoR PF08220.12 AMK75460.1 - 0.0017 18.0 0.8 0.0043 16.8 0.8 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_40 PF14493.6 AMK75460.1 - 0.0034 17.8 0.0 0.0071 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AMK75460.1 - 0.0042 16.6 0.0 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 PadR PF03551.14 AMK75460.1 - 0.0047 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Sigma70_ECF PF07638.11 AMK75460.1 - 0.0093 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 ECF sigma factor Mga PF05043.13 AMK75460.1 - 0.0093 16.5 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 1 Mga helix-turn-helix domain HTH_29 PF13551.6 AMK75460.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix GntR PF00392.21 AMK75460.1 - 0.02 14.5 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Tnp_1_2 PF13022.6 AMK75460.1 - 0.027 14.6 0.2 0.089 12.9 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase DUF4423 PF14394.6 AMK75460.1 - 0.04 13.6 1.3 0.077 12.7 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4423) HTH_10 PF04967.12 AMK75460.1 - 0.04 13.7 0.5 0.097 12.5 0.1 1.8 2 0 0 2 2 1 0 HTH DNA binding domain FaeA PF04703.12 AMK75460.1 - 0.044 14.2 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 FaeA-like protein LcrG PF07216.12 AMK75460.1 - 0.051 13.5 0.5 0.27 11.2 0.0 2.3 2 1 1 3 3 3 0 LcrG protein LexA_DNA_bind PF01726.16 AMK75460.1 - 0.058 13.2 0.2 0.19 11.5 0.1 2.0 2 1 0 2 2 1 0 LexA DNA binding domain DprA_WH PF17782.1 AMK75460.1 - 0.082 13.0 0.6 0.18 11.9 0.6 1.6 1 0 0 1 1 1 0 DprA winged helix domain HTH_9 PF08221.11 AMK75460.1 - 0.095 12.8 0.4 0.22 11.7 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 AMK75460.1 - 0.096 12.6 0.6 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit FeoC PF09012.10 AMK75460.1 - 0.32 11.1 2.2 0.53 10.4 0.0 2.3 2 1 1 3 3 2 0 FeoC like transcriptional regulator MOSC PF03473.17 AMK75461.1 - 1.3e-15 57.6 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 AMK75461.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MFS_1 PF07690.16 AMK75462.1 - 4.7e-68 229.7 145.1 1.4e-37 129.5 36.1 4.0 1 1 3 4 4 4 3 Major Facilitator Superfamily LacY_symp PF01306.19 AMK75462.1 - 0.0054 15.6 30.4 0.011 14.6 10.6 3.4 3 0 0 3 3 3 2 LacY proton/sugar symporter 2-Hacid_dh_C PF02826.19 AMK75462.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3347 PF11827.8 AMK75463.1 - 0.00016 21.9 2.6 0.00019 21.7 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3347) DUF3708 PF12501.8 AMK75463.1 - 0.024 14.4 1.3 0.034 13.9 1.3 1.3 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Cytochrom_C_2 PF01322.20 AMK75463.1 - 0.052 14.5 5.7 0.4 11.6 5.7 2.0 1 1 0 1 1 1 0 Cytochrome C' CDH1_2_SANT_HL1 PF18375.1 AMK75463.1 - 0.13 13.0 0.4 0.28 11.9 0.1 1.7 2 1 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Sec2p PF06428.11 AMK75463.1 - 0.24 11.4 3.2 0.42 10.6 1.0 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Molybdopterin PF00384.22 AMK75464.1 - 7.6e-162 539.2 0.0 9.5e-162 538.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Nitr_red_alph_N PF14710.6 AMK75464.1 - 1.4e-17 63.8 0.7 3.9e-17 62.4 0.7 1.8 1 0 0 1 1 1 1 Respiratory nitrate reductase alpha N-terminal Molydop_binding PF01568.21 AMK75464.1 - 1.6e-17 63.5 0.1 3.8e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AMK75464.1 - 0.0054 16.7 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain RXT2_N PF08595.11 AMK75464.1 - 0.12 12.4 0.0 21 5.1 0.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Fer4_11 PF13247.6 AMK75465.1 - 2.9e-37 126.8 6.8 7.3e-37 125.5 6.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 AMK75465.1 - 3.5e-29 100.3 0.1 6.3e-29 99.5 0.1 1.4 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_10 PF13237.6 AMK75465.1 - 2.5e-09 37.1 16.4 7.7e-07 29.1 4.2 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK75465.1 - 6.3e-08 33.1 18.7 4e-05 24.1 6.4 3.7 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK75465.1 - 1.1e-06 28.4 20.0 0.00012 22.0 0.2 3.8 4 0 0 4 4 3 3 4Fe-4S binding domain Fer4 PF00037.27 AMK75465.1 - 0.00024 20.8 23.0 0.014 15.1 1.9 4.7 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 AMK75465.1 - 0.00028 20.8 23.1 0.05 13.7 1.9 4.0 4 0 0 4 4 3 3 4Fe-4S binding domain Fer4_9 PF13187.6 AMK75465.1 - 0.00031 20.9 19.3 0.33 11.1 0.3 3.3 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AMK75465.1 - 0.00045 20.7 6.9 0.097 13.2 0.1 3.7 3 0 0 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AMK75465.1 - 0.0037 17.6 23.7 0.014 15.9 0.7 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 AMK75465.1 - 0.015 15.4 21.8 0.032 14.4 4.5 3.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AMK75465.1 - 0.061 14.1 8.7 0.39 11.5 0.1 3.1 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 AMK75465.1 - 0.14 12.8 16.4 2.7 8.6 0.1 3.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Nitrate_red_del PF02613.15 AMK75466.1 - 2.1e-13 50.4 2.5 3.2e-13 49.9 2.2 1.5 1 1 0 1 1 1 1 Nitrate reductase delta subunit GvpD PF07088.11 AMK75466.1 - 0.097 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein Nitrate_red_gam PF02665.14 AMK75467.1 - 3.3e-83 278.6 8.4 3.7e-83 278.4 8.4 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Hemerythrin PF01814.23 AMK75468.1 - 1.6e-05 25.5 0.5 1.9e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.23 AMK75469.1 - 1.9e-07 31.7 0.1 2.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain SRP_SPB PF02978.19 AMK75469.1 - 0.0073 16.9 0.0 0.0098 16.5 0.0 1.1 1 0 0 1 1 1 1 Signal peptide binding domain HPP PF04982.13 AMK75470.1 - 1.9e-31 108.8 11.5 3.6e-31 107.9 11.5 1.5 1 0 0 1 1 1 1 HPP family CBS PF00571.28 AMK75470.1 - 2e-17 63.3 0.1 1.4e-08 35.0 0.1 2.4 2 0 0 2 2 2 2 CBS domain Pyr_redox_2 PF07992.14 AMK75471.1 - 3.1e-53 180.9 1.0 4.3e-53 180.4 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 AMK75471.1 - 5.1e-19 68.0 0.2 2.5e-18 65.8 0.1 2.1 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 AMK75471.1 - 7.9e-19 68.0 0.3 1.5e-17 63.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK75471.1 - 2.7e-08 33.4 0.0 5.5e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AMK75471.1 - 4.7e-06 27.0 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 AMK75471.1 - 1.4e-05 25.2 0.7 0.067 13.2 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 AMK75471.1 - 0.00058 19.1 0.0 0.075 12.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 AMK75471.1 - 0.0042 16.0 0.2 0.018 13.9 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 AMK75471.1 - 0.0047 15.7 0.9 1.7 7.3 0.0 3.8 4 1 1 5 5 5 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AMK75471.1 - 0.01 15.2 0.2 0.27 10.5 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AMK75471.1 - 0.011 16.0 0.3 2.5 8.4 0.5 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AMK75471.1 - 0.014 14.5 1.9 2.6 7.0 0.6 3.5 3 1 1 4 4 4 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AMK75471.1 - 0.021 14.1 3.1 3.9 6.6 2.0 2.4 1 1 1 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 AMK75471.1 - 0.022 13.8 4.0 0.75 8.8 1.0 3.3 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 AMK75471.1 - 0.076 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AMK75471.1 - 0.097 12.2 1.1 2.6 7.5 0.9 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AMK75471.1 - 0.11 11.6 0.3 3.3 6.7 0.1 2.4 2 1 1 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.20 AMK75471.1 - 0.12 12.4 0.5 6.5 6.8 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF1139 PF06599.11 AMK75471.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) PhzC-PhzF PF02567.16 AMK75472.1 - 5.3e-50 170.5 0.0 6.1e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 AMK75472.1 - 0.12 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Proline racemase Rieske_2 PF13806.6 AMK75473.1 - 1.2e-39 134.4 0.0 1.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF4656 PF15551.6 AMK75473.1 - 0.00097 18.8 0.0 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4656) Pyr_redox_2 PF07992.14 AMK75474.1 - 3e-49 167.8 0.2 5e-49 167.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 AMK75474.1 - 2.1e-19 69.6 0.0 5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 AMK75474.1 - 2e-17 63.5 3.1 1.2e-14 54.6 0.2 3.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AMK75474.1 - 1.1e-15 57.7 6.3 3.6e-10 40.0 4.2 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rubredoxin_C PF18267.1 AMK75474.1 - 2.2e-11 43.5 0.3 5.8e-11 42.2 0.3 1.8 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain NIR_SIR_ferr PF03460.17 AMK75474.1 - 7.9e-10 38.4 0.0 3.7e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 AMK75474.1 - 0.0002 20.7 0.0 0.00035 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK75474.1 - 0.0044 16.6 1.2 0.048 13.2 0.0 2.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 AMK75474.1 - 0.0074 15.4 0.0 0.57 9.2 0.1 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AMK75474.1 - 0.016 15.5 0.1 0.052 13.8 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 AMK75474.1 - 0.027 13.6 0.0 0.074 12.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 AMK75474.1 - 0.04 13.0 1.9 0.71 8.9 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_dim PF02852.22 AMK75474.1 - 0.047 14.0 0.0 0.64 10.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain AlaDh_PNT_C PF01262.21 AMK75474.1 - 0.25 10.6 1.9 0.17 11.1 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Form_Nir_trans PF01226.17 AMK75475.1 - 7.5e-64 215.3 26.3 8.4e-64 215.1 26.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Trp_oprn_chp PF09534.10 AMK75475.1 - 1.2 8.9 9.0 0.38 10.5 2.5 2.1 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 AMK75476.1 - 2e-39 135.5 75.5 7.4e-32 110.6 49.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AMK75476.1 - 1.1e-08 34.4 29.3 3.5e-07 29.4 4.4 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter Pkinase PF00069.25 AMK75478.1 - 2.7e-36 125.3 0.0 3.8e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AMK75478.1 - 3.2e-24 85.6 0.0 4.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 AMK75478.1 - 2e-13 50.4 0.1 3.2e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AMK75478.1 - 5.4e-08 32.8 0.1 2.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Kdo PF06293.14 AMK75478.1 - 1.2e-05 24.8 0.5 2.5e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AMK75478.1 - 0.00014 21.9 0.0 0.084 12.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family SpoIIE PF07228.12 AMK75478.1 - 0.00016 21.7 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Seadorna_VP7 PF07387.11 AMK75478.1 - 0.0054 15.8 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 TraL PF07178.11 AMK75479.1 - 6.4e-28 97.1 0.3 7.1e-28 96.9 0.3 1.0 1 0 0 1 1 1 1 TraL protein TraE PF05309.11 AMK75480.1 - 6.8e-26 90.8 0.0 7.8e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 TraE protein TraK PF06586.11 AMK75481.1 - 3.6e-16 59.6 0.4 4.9e-16 59.1 0.4 1.1 1 0 0 1 1 1 1 TraK protein TrbI PF03743.14 AMK75482.1 - 2.2e-34 119.0 0.0 4.7e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein DUF2913 PF11140.8 AMK75482.1 - 0.18 11.5 0.4 0.31 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Thioredoxin_2 PF13098.6 AMK75483.1 - 4.1e-12 46.5 0.0 8.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 AMK75483.1 - 1.1e-05 24.8 0.0 2.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 AMK75483.1 - 0.00025 20.9 0.6 0.01 15.6 0.0 2.6 2 1 1 3 3 3 1 DSBA-like thioredoxin domain TraF PF13728.6 AMK75483.1 - 0.00032 20.6 0.0 0.00075 19.4 0.0 1.6 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 AMK75483.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 AMK75483.1 - 0.037 14.4 0.0 0.08 13.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like zinc_ribbon_15 PF17032.5 AMK75483.1 - 0.041 14.6 0.0 0.062 14.1 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon family Thioredoxin_4 PF13462.6 AMK75483.1 - 0.047 13.8 0.0 0.091 12.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 AMK75483.1 - 0.06 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_5 PF13743.6 AMK75483.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 AMK75483.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Redoxin TraV PF09676.10 AMK75484.1 - 5e-18 66.4 7.5 3.5e-15 57.1 3.4 2.3 1 1 1 2 2 2 2 Type IV conjugative transfer system lipoprotein (TraV) TrbC PF04956.13 AMK75485.1 - 4e-06 26.9 11.8 4.5e-06 26.8 11.8 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DctM PF06808.12 AMK75485.1 - 0.0011 17.9 9.0 0.0011 17.9 9.0 1.3 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component RRXRR PF14239.6 AMK75486.1 - 7e-08 32.5 0.2 8.6e-08 32.2 0.2 1.1 1 0 0 1 1 1 1 RRXRR protein GPR15L PF15854.5 AMK75486.1 - 0.82 9.9 6.5 1.8 8.8 1.7 1.9 1 1 1 2 2 2 0 G-protein coupled receptor ligand 15 TraC_F_IV PF11130.8 AMK75487.1 - 3e-47 161.3 0.1 5.4e-47 160.4 0.1 1.5 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 AMK75487.1 - 6e-11 41.9 0.0 1.2e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.6 AMK75487.1 - 0.041 14.2 0.5 5.9 7.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain TraG-D_C PF12696.7 AMK75487.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF87 PF01935.17 AMK75487.1 - 0.17 11.9 0.0 0.53 10.3 0.0 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain HemX PF04375.14 AMK75488.1 - 0.019 14.2 0.6 0.034 13.4 0.6 1.4 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Peptidase_S26 PF10502.9 AMK75489.1 - 3.4e-12 46.3 0.0 6.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 TrbC_Ftype PF09673.10 AMK75490.1 - 5.9e-18 65.0 0.0 1.2e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 Type-F conjugative transfer system pilin assembly protein TraU PF06834.11 AMK75491.1 - 1.8e-97 326.3 0.2 2.3e-97 326.0 0.2 1.0 1 0 0 1 1 1 1 TraU protein TraN PF06986.11 AMK75492.1 - 1e-39 136.7 22.2 4.8e-24 85.4 0.8 2.6 2 0 0 2 2 2 2 Type-1V conjugative transfer system mating pair stabilisation Bac_DNA_binding PF00216.21 AMK75493.1 - 8.6e-33 112.4 0.0 9.4e-33 112.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AMK75493.1 - 4.4e-08 33.3 0.0 4.6e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AMK75493.1 - 0.00056 19.7 0.0 0.0008 19.2 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AMK75493.1 - 0.00091 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AMK75493.1 - 0.018 15.1 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 DUF45 PF01863.17 AMK75494.1 - 1.1e-57 195.5 1.5 1.3e-57 195.2 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AMK75494.1 - 0.00052 20.1 0.1 0.00096 19.3 0.1 1.4 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 AMK75494.1 - 0.0016 18.3 0.3 0.0028 17.5 0.3 1.4 1 0 0 1 1 1 1 SprT-like family SWI2_SNF2 PF18766.1 AMK75495.1 - 1.4e-75 253.8 0.0 3.1e-75 252.7 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 AMK75495.1 - 2.7e-36 125.4 0.0 9e-36 123.6 0.0 1.9 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 AMK75495.1 - 1.3e-20 74.1 0.0 3.7e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Beta_protein PF14350.6 AMK75495.1 - 0.019 14.4 0.1 0.046 13.1 0.1 1.6 1 0 0 1 1 1 0 Beta protein DUF3387 PF11867.8 AMK75495.1 - 0.053 12.9 3.4 0.059 12.7 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3387) SAPI PF16560.5 AMK75495.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative mobile pathogenicity island UvrD-helicase PF00580.21 AMK75495.1 - 0.097 12.2 2.2 9.4 5.7 0.0 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PheRS_DBD2 PF18554.1 AMK75495.1 - 1.2 9.2 3.4 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 PheRS DNA binding domain 2 Fic PF02661.18 AMK75496.1 - 3.1e-23 82.5 0.0 8.9e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 Fic/DOC family Methylase_S PF01420.19 AMK75497.1 - 4.9e-28 98.4 0.0 3.6e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain DivIC PF04977.15 AMK75497.1 - 0.29 10.9 2.5 2.5 7.9 1.3 2.9 2 1 1 3 3 3 0 Septum formation initiator Bro-N PF02498.17 AMK75498.1 - 6.6e-07 29.9 0.1 6.3e-06 26.8 0.0 2.4 2 1 1 3 3 3 1 BRO family, N-terminal domain N6_Mtase PF02384.16 AMK75499.1 - 2.3e-107 358.9 0.0 4.2e-107 358.0 0.0 1.4 2 0 0 2 2 2 1 N-6 DNA Methylase HsdM_N PF12161.8 AMK75499.1 - 5.1e-23 82.2 0.4 5.1e-23 82.2 0.4 2.0 2 0 0 2 2 2 1 HsdM N-terminal domain Eco57I PF07669.11 AMK75499.1 - 0.0092 16.5 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 Eco57I restriction-modification methylase UPF0020 PF01170.18 AMK75499.1 - 0.06 13.0 0.2 0.21 11.2 0.2 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 cwf21 PF08312.12 AMK75499.1 - 0.19 11.9 2.7 2.3 8.5 0.0 2.8 2 0 0 2 2 2 0 cwf21 domain TSC22 PF01166.18 AMK75499.1 - 0.41 11.0 2.3 0.47 10.8 0.6 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Methylase_S PF01420.19 AMK75500.1 - 7.8e-07 29.5 0.0 9.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Type I restriction modification DNA specificity domain Prok-E2_A PF14457.6 AMK75502.1 - 1.3e-31 109.4 0.0 7.9e-31 106.9 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family A Prok-JAB PF14464.6 AMK75502.1 - 2.7e-12 46.5 0.0 4.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ThiF PF00899.21 AMK75502.1 - 2.8e-11 43.3 0.0 4.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family ABC_transp_aux PF09822.9 AMK75502.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system 3HCDH_N PF02737.18 AMK75502.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gram_pos_anchor PF00746.21 AMK75503.1 - 4.9 7.2 5.8 0.86 9.6 0.2 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif HEPN_RiboL-PSP PF18735.1 AMK75504.1 - 9.2e-22 77.9 0.0 1.2e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 RiboL-PSP-HEPN SLATT_fungal PF18142.1 AMK75504.1 - 0.099 12.6 0.3 0.49 10.4 0.0 2.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Nse5 PF08691.10 AMK75505.1 - 0.027 13.1 0.1 0.031 13.0 0.1 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 SSB PF00436.25 AMK75506.1 - 5.6e-33 113.1 0.0 6.8e-33 112.8 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AMK75506.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FOG_N PF15888.5 AMK75506.1 - 0.099 13.0 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 Folded gastrulation N-terminus RecT PF03837.14 AMK75507.1 - 1.2e-16 60.8 0.1 2.1e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 RecT family YqaJ PF09588.10 AMK75509.1 - 8.3e-23 81.2 0.0 1.4e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain AAA_5 PF07728.14 AMK75511.1 - 7.9e-20 71.3 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 AMK75511.1 - 7.8e-19 67.7 0.1 1.2e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA PF00004.29 AMK75511.1 - 2e-05 25.0 0.0 3.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK75511.1 - 4.1e-05 24.0 0.0 8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AMK75511.1 - 0.0029 17.6 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 AMK75511.1 - 0.0043 16.5 0.1 1.2 8.5 0.1 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AMK75511.1 - 0.0046 17.2 0.4 0.0098 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AMK75511.1 - 0.013 15.8 0.2 0.029 14.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 AMK75511.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_7 PF17867.1 AMK75511.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_29 PF13555.6 AMK75511.1 - 0.028 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 AMK75511.1 - 0.034 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 AMK75511.1 - 0.037 14.6 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AMK75511.1 - 0.04 14.4 0.1 0.072 13.6 0.1 1.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 AMK75511.1 - 0.045 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AMK75511.1 - 0.045 13.3 0.3 0.099 12.2 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AMK75511.1 - 0.065 13.7 0.0 0.096 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 AMK75511.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_33 PF13671.6 AMK75511.1 - 0.1 12.8 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AMK75511.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_9 PF12781.7 AMK75511.1 - 0.27 10.4 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region DUF3150 PF11348.8 AMK75513.1 - 8.5e-92 307.0 0.0 1e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) VWA PF00092.28 AMK75514.1 - 8.5e-09 35.9 0.0 2.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain CobT PF06213.12 AMK75514.1 - 1.1e-08 34.9 7.9 5.2e-08 32.6 7.9 2.1 1 1 0 1 1 1 1 Cobalamin biosynthesis protein CobT CobT_C PF11775.8 AMK75514.1 - 0.00014 21.5 0.0 0.034 13.8 0.0 3.1 2 1 0 2 2 2 1 Cobalamin biosynthesis protein CobT VWA domain eIF-3c_N PF05470.12 AMK75514.1 - 0.85 7.9 7.8 1.2 7.3 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 AMK75514.1 - 6 6.1 14.4 8.2 5.7 14.4 1.1 1 0 0 1 1 1 0 BUD22 Striatin PF08232.12 AMK75514.1 - 6.5 7.3 7.3 14 6.2 7.2 1.6 1 1 0 1 1 1 0 Striatin family Presenilin PF01080.17 AMK75514.1 - 8.3 5.1 6.0 12 4.6 6.0 1.1 1 0 0 1 1 1 0 Presenilin zf-3CxxC_2 PF17180.4 AMK75517.1 - 0.0026 18.5 3.3 0.0038 17.9 2.3 1.7 2 0 0 2 2 2 1 Zinc-binding domain HypA PF01155.19 AMK75517.1 - 0.027 14.5 0.9 0.066 13.2 0.9 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AhpC-TSA PF00578.21 AMK75517.1 - 0.056 13.4 2.7 5.1 7.0 0.0 3.1 3 0 0 3 3 3 0 AhpC/TSA family zinc-ribbons_6 PF07191.12 AMK75517.1 - 0.24 11.4 4.9 0.57 10.2 4.9 1.5 1 1 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.9 AMK75517.1 - 0.74 9.9 0.1 0.74 9.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF4942 PF13708.6 AMK75519.1 - 1.2e-47 162.5 0.1 2e-47 161.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4942) MTS PF05175.14 AMK75519.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HATPase_c_3 PF13589.6 AMK75520.1 - 0.001 18.9 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AMK75520.1 - 0.067 13.7 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RVT_N PF13655.6 AMK75521.1 - 6.7e-33 112.8 4.5 8.7e-33 112.4 4.5 1.1 1 0 0 1 1 1 1 N-terminal domain of reverse transcriptase TetR_N PF00440.23 AMK75522.1 - 1e-08 34.8 0.0 2.8e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_17 PF17922.1 AMK75522.1 - 4.7e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AMK75522.1 - 6.8e-05 22.9 0.5 0.00027 21.0 0.1 2.0 1 1 1 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_24 PF17932.1 AMK75522.1 - 0.0003 21.0 0.0 0.00079 19.7 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 AMK75522.1 - 0.00075 19.7 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_11 PF16859.5 AMK75522.1 - 0.001 19.4 0.7 0.0042 17.4 0.1 2.2 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 AMK75522.1 - 0.0044 17.2 2.9 0.0056 16.9 0.2 2.4 2 2 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_29 PF17938.1 AMK75522.1 - 0.0074 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 AMK75522.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 AMK75522.1 - 0.012 16.4 0.7 0.045 14.5 0.1 2.1 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_2 PF08361.11 AMK75522.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region HlyD_D23 PF16576.5 AMK75523.1 - 1.1e-14 54.2 5.6 2.5e-13 49.7 5.6 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK75523.1 - 5.2e-12 46.4 1.5 8.5e-10 39.3 0.1 3.0 2 1 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK75523.1 - 6.1e-05 22.8 6.8 6.1e-05 22.8 6.8 3.2 2 1 0 2 2 2 1 Biotin-lipoyl like ATP-synt_ab_Xtn PF16886.5 AMK75523.1 - 0.0019 18.1 0.1 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Peptidase_M23 PF01551.22 AMK75523.1 - 0.014 15.6 1.1 1.8 8.8 0.1 3.0 2 1 0 3 3 3 0 Peptidase family M23 Biotin_lipoyl PF00364.22 AMK75523.1 - 0.069 13.0 0.2 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Biotin-requiring enzyme Golgin_A5 PF09787.9 AMK75523.1 - 0.46 9.9 5.2 0.67 9.4 5.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5082 PF16888.5 AMK75523.1 - 0.5 10.6 6.6 0.91 9.8 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) MacB_PCD PF12704.7 AMK75524.1 - 8.9e-10 39.2 0.2 8.9e-10 39.2 0.2 1.7 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AMK75524.1 - 3.5e-06 27.4 5.5 3.5e-06 27.4 5.5 3.3 3 1 0 3 3 3 1 FtsX-like permease family CCB1 PF12046.8 AMK75524.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B LAX PF15681.5 AMK75524.1 - 0.18 10.6 0.2 9.4 4.9 0.0 2.1 2 0 0 2 2 2 0 Lymphocyte activation family X ABC_tran PF00005.27 AMK75525.1 - 3.8e-32 111.7 0.0 6.1e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AMK75525.1 - 8.1e-08 32.0 0.1 8.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK75525.1 - 2.4e-07 30.9 0.1 0.00071 19.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AMK75525.1 - 1.8e-05 25.2 0.0 2.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AMK75525.1 - 8.8e-05 22.2 0.2 0.00018 21.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AMK75525.1 - 0.0035 16.9 1.4 0.11 12.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AMK75525.1 - 0.0067 16.7 1.0 0.21 11.9 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AMK75525.1 - 0.0073 16.8 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AMK75525.1 - 0.0088 15.8 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 AMK75525.1 - 0.0089 16.2 1.4 0.04 14.1 0.8 2.6 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 AMK75525.1 - 0.011 14.8 0.2 0.017 14.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 AMK75525.1 - 0.015 15.3 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AMK75525.1 - 0.021 14.6 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AMK75525.1 - 0.029 14.9 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 AMK75525.1 - 0.052 13.3 0.1 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 AMK75525.1 - 0.081 12.1 0.2 0.16 11.1 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 AMK75525.1 - 0.095 12.8 0.3 0.44 10.6 0.2 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 AMK75525.1 - 0.096 11.9 0.6 0.26 10.5 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.6 AMK75525.1 - 0.21 11.3 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AMK75525.1 - 0.23 11.0 0.6 0.43 10.1 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 AMK75525.1 - 0.28 11.6 0.6 1.7 9.1 0.2 2.4 3 1 0 3 3 3 0 RNA helicase MarR PF01047.22 AMK75526.1 - 2.1e-15 56.4 0.5 2.1e-14 53.2 0.1 2.1 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AMK75526.1 - 1.6e-12 47.1 0.5 7.3e-12 45.0 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 AMK75526.1 - 1.7e-06 28.4 0.3 2.3e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AMK75526.1 - 2.6e-05 24.2 0.4 0.051 13.6 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain TrmB PF01978.19 AMK75526.1 - 0.00045 20.1 0.2 0.065 13.1 0.0 2.7 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AMK75526.1 - 0.0026 17.3 1.1 0.0052 16.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 AMK75526.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 AMK75526.1 - 0.033 14.1 0.2 0.081 12.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 AMK75526.1 - 0.066 13.6 0.2 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator HTH_Crp_2 PF13545.6 AMK75526.1 - 0.071 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AMK75526.1 - 0.071 13.3 0.2 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_36 PF13730.6 AMK75526.1 - 0.079 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain RHH_4 PF13467.6 AMK75526.1 - 0.1 12.5 0.9 0.45 10.4 0.1 2.2 2 1 0 2 2 2 0 Ribbon-helix-helix domain TFIIE_alpha PF02002.17 AMK75526.1 - 0.19 11.6 2.0 0.58 10.1 2.0 1.8 1 1 0 1 1 1 0 TFIIE alpha subunit Sulfate_transp PF00916.20 AMK75527.1 - 4.2e-54 183.8 28.4 2.7e-27 95.5 16.9 2.2 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 AMK75527.1 - 5.5e-09 35.7 0.3 1.1e-08 34.7 0.3 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AMK75527.1 - 0.0073 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain Usp PF00582.26 AMK75528.1 - 5e-24 85.4 5.0 3.6e-09 37.3 1.6 3.8 2 2 1 3 3 3 3 Universal stress protein family Calici_MSP PF05752.11 AMK75528.1 - 0.011 15.6 0.1 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Calicivirus minor structural protein NleF_casp_inhib PF16809.5 AMK75528.1 - 0.11 12.5 0.1 4.2 7.3 0.0 2.3 1 1 1 2 2 2 0 NleF caspase inhibitor FerA PF08165.11 AMK75528.1 - 0.16 11.9 1.5 0.41 10.6 1.5 1.7 1 0 0 1 1 1 0 FerA (NUC095) domain DEAD_assoc PF08494.11 AMK75529.1 - 0.089 12.6 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 DEAD/H associated DDE_Tnp_1 PF01609.21 AMK75531.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK75531.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK75531.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK75531.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK75531.1 - 0.0091 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK75531.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK75531.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK75531.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK75531.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK75531.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK75531.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK75531.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK75531.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain PHO4 PF01384.20 AMK75532.1 - 2.3e-57 194.6 21.1 2.7e-57 194.3 21.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 AMK75532.1 - 0.0072 16.1 0.5 1.1 9.1 0.1 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain DUF742 PF05331.11 AMK75532.1 - 0.26 11.1 1.5 3.1 7.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF742) ATP_synth_reg PF14960.6 AMK75532.1 - 0.28 10.7 1.6 1.1 8.9 1.6 2.0 1 0 0 1 1 1 0 ATP synthase regulation DUF1348 PF07080.11 AMK75533.1 - 1.6e-65 218.9 6.0 1.8e-65 218.7 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 AMK75533.1 - 6.8e-08 33.1 1.7 9e-08 32.7 1.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AMK75533.1 - 5.8e-05 23.4 0.2 8.8e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 AMK75533.1 - 0.00036 20.3 0.3 0.00054 19.8 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase GST_N_3 PF13417.6 AMK75534.1 - 1.7e-16 60.4 0.0 6.1e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK75534.1 - 1.1e-14 54.5 0.0 1.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AMK75534.1 - 3.3e-14 52.9 0.0 5.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AMK75534.1 - 1.7e-11 44.2 0.0 3.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AMK75534.1 - 6.6e-08 32.7 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AMK75534.1 - 9.8e-07 28.7 1.9 1.7e-06 27.9 0.2 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AMK75534.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AMK75534.1 - 0.061 14.1 0.0 0.41 11.4 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Putative_PNPOx PF01243.20 AMK75535.1 - 3.5e-12 46.3 0.0 7.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 AMK75535.1 - 8.5e-07 29.6 0.0 2.8e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 AMK75535.1 - 0.0065 16.6 0.4 1.5 8.9 0.3 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 AMK75535.1 - 0.0075 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain CMD PF02627.20 AMK75536.1 - 4.6e-16 58.6 3.5 1.4e-14 53.9 2.1 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 AMK75536.1 - 0.052 12.5 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2717 PF10911.8 AMK75536.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) UBA_6 PF18039.1 AMK75536.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain LysR_substrate PF03466.20 AMK75537.1 - 2.6e-40 138.0 0.8 3.4e-40 137.6 0.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK75537.1 - 1.1e-18 66.9 0.3 2.6e-18 65.7 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 AMK75537.1 - 0.0011 18.8 0.3 0.042 13.7 0.1 2.6 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AMK75537.1 - 0.0079 16.1 0.1 0.084 12.8 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 AMK75537.1 - 0.051 13.1 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FlhD PF05247.13 AMK75539.1 - 1.9e-06 28.1 0.0 2.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF4325 PF14213.6 AMK75540.1 - 2.7e-12 46.2 0.3 5.7e-12 45.2 0.3 1.5 1 0 0 1 1 1 1 STAS-like domain of unknown function (DUF4325) FlhD PF05247.13 AMK75540.1 - 0.0051 17.0 0.0 0.0097 16.2 0.0 1.4 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF713 PF05218.14 AMK75540.1 - 0.02 14.6 0.6 0.028 14.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) FlhC PF05280.11 AMK75541.1 - 2.7e-15 56.5 0.0 3.2e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) DUF2719 PF10891.8 AMK75541.1 - 0.078 12.9 0.1 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) HTH_17 PF12728.7 AMK75542.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2635 PF10948.8 AMK75542.1 - 0.091 12.5 0.1 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) CAS_CSE1 PF03378.15 AMK75542.1 - 0.094 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus CsrA PF02599.16 AMK75543.1 - 3.2e-27 94.2 1.7 3.6e-27 94.1 1.7 1.0 1 0 0 1 1 1 1 Global regulator protein family DUF1236 PF06823.12 AMK75544.1 - 9.9e-06 25.3 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1236) RcnB PF11776.8 AMK75544.1 - 7.4e-05 22.7 0.3 0.00057 19.9 0.0 2.5 2 0 0 2 2 2 1 Nickel/cobalt transporter regulator Herpes_LMP2 PF07415.11 AMK75544.1 - 2.4 6.8 4.0 3.4 6.3 4.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF2845 PF11006.8 AMK75545.1 - 2e-24 85.5 0.0 2.4e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2845) SoxY PF13501.6 AMK75546.1 - 5.1e-37 126.5 0.0 8e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 Sulfur oxidation protein SoxY SoxZ PF08770.11 AMK75546.1 - 1.2e-24 85.9 0.0 2.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ Lactamase_B PF00753.27 AMK75547.1 - 2.9e-19 69.9 1.9 4.4e-19 69.3 1.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK75547.1 - 0.0024 17.4 0.4 0.0056 16.2 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Herpes_IE68 PF02479.16 AMK75547.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus immediate early protein Pep_deformylase PF01327.21 AMK75548.1 - 2.4e-47 160.5 0.0 3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Polysacc_synt_4 PF04669.13 AMK75548.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis Fe-S_biosyn PF01521.20 AMK75550.1 - 3.5e-22 78.7 0.0 3.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CEP19 PF14933.6 AMK75550.1 - 0.013 15.8 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein Aminotran_5 PF00266.19 AMK75551.1 - 2.1e-65 221.1 0.0 2.5e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Rrf2 PF02082.20 AMK75552.1 - 1.7e-29 101.9 0.2 3.5e-29 101.0 0.1 1.5 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 AMK75552.1 - 0.00021 20.9 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MarR_2 PF12802.7 AMK75552.1 - 0.0079 16.1 0.1 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 AMK75552.1 - 0.046 13.8 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FaeA PF04703.12 AMK75552.1 - 0.049 14.0 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 FaeA-like protein Hexapep PF00132.24 AMK75553.1 - 3.9e-14 51.7 9.5 1.4e-07 31.0 3.2 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AMK75553.1 - 4e-05 23.3 13.2 0.0022 17.7 5.2 3.3 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 AMK75553.1 - 0.00015 22.1 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal SPATA24 PF15175.6 AMK75553.1 - 0.14 12.1 0.4 0.18 11.7 0.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 SpoU_methylase PF00588.19 AMK75554.1 - 7.9e-36 123.3 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Inositol_P PF00459.25 AMK75555.1 - 2.4e-72 243.7 0.0 2.9e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Mpt_N PF09176.11 AMK75556.1 - 1.7e-36 124.2 0.2 7.9e-36 122.0 0.0 2.2 2 1 1 3 3 3 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Shikimate_DH PF01488.20 AMK75556.1 - 0.00039 20.5 0.5 0.00069 19.7 0.2 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AMK75556.1 - 0.00068 20.2 2.0 0.0015 19.1 1.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 AMK75556.1 - 0.00071 18.9 4.1 0.0011 18.3 4.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.19 AMK75556.1 - 0.0043 16.4 1.2 0.097 12.0 1.2 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 AMK75556.1 - 0.0073 15.8 2.2 0.013 15.0 1.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase ELFV_dehydrog PF00208.21 AMK75556.1 - 0.0092 15.7 1.1 0.017 14.9 1.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 AMK75556.1 - 0.015 14.7 1.6 0.031 13.6 0.2 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 AMK75556.1 - 0.019 14.5 3.2 0.029 13.9 3.2 1.3 1 0 0 1 1 1 0 NmrA-like family GIDA PF01134.22 AMK75556.1 - 0.04 13.0 2.8 0.061 12.4 2.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 AMK75556.1 - 0.044 13.7 1.3 0.074 12.9 1.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AMK75556.1 - 0.13 12.7 0.5 0.22 12.0 0.5 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Mpt_N PF09176.11 AMK75557.1 - 1.1e-36 124.8 0.1 2.6e-36 123.6 0.1 1.7 1 0 0 1 1 1 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Semialdhyde_dh PF01118.24 AMK75557.1 - 0.0015 18.9 0.6 0.21 12.0 0.3 2.2 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain Response_reg PF00072.24 AMK75558.1 - 1.4e-28 99.3 0.0 2.1e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK75558.1 - 3.3e-17 61.8 0.4 4.9e-17 61.2 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AMK75558.1 - 1.3e-06 28.0 0.5 2.4e-06 27.1 0.5 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 AMK75558.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 AMK75558.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2089 PF09862.9 AMK75558.1 - 0.066 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_Tnp_ISL3 PF13542.6 AMK75558.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AMK75558.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain tRNA-synt_2b PF00587.25 AMK75559.1 - 2.6e-48 164.4 0.0 4.2e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 AMK75559.1 - 4.5e-26 91.3 0.0 9.8e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 AMK75559.1 - 1.2e-21 76.7 0.0 2.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DNA_pol3_delta PF06144.13 AMK75561.1 - 1.2e-31 109.9 0.0 2e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delt_C PF14840.6 AMK75561.1 - 1.7e-14 54.3 0.3 2.9e-14 53.5 0.3 1.4 1 0 0 1 1 1 1 Processivity clamp loader gamma complex DNA pol III C-term LptE PF04390.12 AMK75562.1 - 1.5e-07 32.0 0.1 1.9e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly tRNA-synt_1_2 PF13603.6 AMK75563.1 - 1.4e-74 249.6 0.0 2.9e-74 248.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 AMK75563.1 - 1.6e-73 248.0 2.8 1.2e-28 99.8 0.3 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 AMK75563.1 - 2.8e-30 105.4 0.0 9.8e-22 77.2 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AMK75563.1 - 6.5e-20 71.6 0.1 1.3e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DZR PF12773.7 AMK75563.1 - 0.0041 17.1 4.1 0.014 15.4 0.1 2.4 2 0 0 2 2 2 1 Double zinc ribbon DUF4184 PF13803.6 AMK75563.1 - 0.0049 16.6 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4184) tRNA-synt_1f PF01921.18 AMK75563.1 - 0.013 14.4 0.0 6 5.7 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 AMK75563.1 - 0.016 14.6 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 AMK75563.1 - 0.035 13.5 6.1 0.66 9.5 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Enolase_N PF03952.16 AMK75563.1 - 0.11 12.6 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Enolase, N-terminal domain DUF1451 PF07295.11 AMK75564.1 - 2.7e-44 150.7 0.0 3.1e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 AMK75564.1 - 0.0025 17.9 0.6 0.0053 16.9 0.6 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 AMK75564.1 - 0.006 16.5 0.7 0.89 9.6 0.0 2.3 2 0 0 2 2 2 1 PhnA Zinc-Ribbon HypA PF01155.19 AMK75564.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EAV_GS PF01309.18 AMK75564.1 - 0.034 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein TF_Zn_Ribbon PF08271.12 AMK75564.1 - 0.092 12.3 1.5 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 AMK75564.1 - 0.28 10.8 3.1 0.34 10.5 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 AMK75564.1 - 0.48 10.1 0.1 0.48 10.1 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-DNL PF05180.12 AMK75564.1 - 1.5 8.8 3.3 44 4.1 1.4 2.8 2 1 0 2 2 2 0 DNL zinc finger zf-C2H2_6 PF13912.6 AMK75564.1 - 6.1 7.0 8.7 45 4.2 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger AAA_31 PF13614.6 AMK75565.1 - 1.9e-37 128.9 0.0 2.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK75565.1 - 6.8e-23 81.1 0.0 9.5e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 AMK75565.1 - 1.8e-13 50.6 0.5 2.5e-07 30.4 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 AMK75565.1 - 9.8e-10 38.3 0.1 9.8e-10 38.3 0.1 1.8 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AMK75565.1 - 7.5e-08 32.0 0.1 1.8e-06 27.5 0.1 2.2 2 1 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 AMK75565.1 - 1.4e-06 27.7 1.1 5.3e-06 25.8 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AMK75565.1 - 0.0032 17.0 0.6 0.85 9.1 0.1 2.4 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 AMK75565.1 - 0.02 14.7 0.8 0.08 12.7 0.0 2.1 2 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 AMK75565.1 - 0.077 12.6 0.0 0.5 9.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain PK PF00224.21 AMK75567.1 - 1.6e-46 158.8 0.0 4.3e-37 127.8 0.0 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PhoU PF01895.19 AMK75568.1 - 1.7e-24 86.1 9.4 1.6e-14 54.2 0.9 2.1 2 0 0 2 2 2 2 PhoU domain Metallophos_2 PF12850.7 AMK75569.1 - 5.2e-14 52.8 2.4 2.4e-13 50.6 2.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AMK75569.1 - 2e-11 44.8 6.2 3.5e-11 44.0 5.8 1.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase YtxC PF08812.11 AMK75569.1 - 0.018 14.7 0.5 0.048 13.3 0.1 1.9 3 0 0 3 3 3 0 YtxC-like family LTD PF00932.19 AMK75570.1 - 2.1e-06 28.1 0.7 6e-06 26.6 0.7 1.9 1 0 0 1 1 1 1 Lamin Tail Domain Exo_endo_phos PF03372.23 AMK75570.1 - 3.7e-05 23.4 0.2 0.00012 21.7 0.0 2.0 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Dockerin_1 PF00404.18 AMK75570.1 - 0.015 15.5 0.9 0.041 14.1 0.9 1.8 1 0 0 1 1 1 0 Dockerin type I domain DUF2345 PF10106.9 AMK75571.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF3540 PF12059.8 AMK75571.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) DUF502 PF04367.13 AMK75573.1 - 0.0041 17.0 0.2 2.4 8.1 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF502) PEP-CTERM PF07589.11 AMK75574.1 - 0.072 13.2 1.9 0.2 11.8 1.9 1.8 1 0 0 1 1 1 0 PEP-CTERM motif 5_nucleotid_C PF02872.18 AMK75575.1 - 2.3e-34 118.9 1.2 3.9e-34 118.1 0.3 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 AMK75575.1 - 3.2e-07 31.1 0.0 5.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK75575.1 - 0.045 13.9 0.0 0.48 10.6 0.0 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF1403 PF07183.11 AMK75575.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) LPAM_1 PF08139.12 AMK75576.1 - 0.043 14.3 2.0 0.077 13.5 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site VirB7 PF17413.2 AMK75576.1 - 0.13 11.6 0.8 0.25 10.7 0.8 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 Alk_phosphatase PF00245.20 AMK75577.1 - 1.1e-124 416.6 6.1 2.1e-124 415.7 6.1 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 AMK75577.1 - 3.3e-05 23.4 0.0 6.9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily DUF1729 PF08354.10 AMK75577.1 - 0.063 12.2 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) HTH_20 PF12840.7 AMK75578.1 - 2e-11 43.7 0.2 2.9e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AMK75578.1 - 2e-06 27.6 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AMK75578.1 - 0.0085 16.0 0.1 0.025 14.4 0.1 1.7 1 1 1 2 2 2 1 MarR family TrmB PF01978.19 AMK75578.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 AMK75578.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.8 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding RP-C PF03428.13 AMK75578.1 - 0.091 12.4 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain HTH_10 PF04967.12 AMK75578.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_IclR PF09339.10 AMK75578.1 - 0.11 12.3 0.2 0.29 11.0 0.2 1.7 1 1 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 AMK75578.1 - 0.12 12.7 0.1 0.47 10.8 0.1 1.9 1 1 0 1 1 1 0 Transcriptional regulator LMWPc PF01451.21 AMK75579.1 - 3.4e-19 69.6 0.0 4.2e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ArsD PF06953.11 AMK75580.1 - 3.5e-49 166.2 0.1 3.9e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 Arsenical resistance operon trans-acting repressor ArsD Thioredoxin_3 PF13192.6 AMK75580.1 - 0.0038 17.2 0.0 0.0059 16.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin domain ArsA_ATPase PF02374.15 AMK75581.1 - 1.5e-93 313.4 0.0 3e-52 177.7 0.0 4.1 2 2 1 3 3 3 3 Anion-transporting ATPase CbiA PF01656.23 AMK75581.1 - 7.1e-22 77.8 0.0 8.2e-10 38.8 0.0 2.7 2 2 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AMK75581.1 - 1.3e-19 70.8 0.0 6e-10 39.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain ParA PF10609.9 AMK75581.1 - 9.4e-11 41.6 4.6 4.5e-05 23.0 0.2 2.7 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 AMK75581.1 - 5.7e-10 39.2 0.0 0.00047 19.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Fer4_NifH PF00142.18 AMK75581.1 - 4.1e-09 36.3 0.1 0.0031 17.0 0.0 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhoH PF02562.16 AMK75581.1 - 4.3e-09 36.1 0.2 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 AMK75581.1 - 5.9e-09 35.8 4.4 1.1e-05 25.2 0.5 3.2 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 AMK75581.1 - 8.9e-09 36.0 6.9 5.3e-05 23.7 1.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 AMK75581.1 - 7.7e-07 28.4 2.7 0.011 14.7 0.1 2.7 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 AMK75581.1 - 8.4e-07 28.7 2.8 0.0044 16.5 0.0 2.9 3 1 0 3 3 3 2 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 AMK75581.1 - 1.2e-06 28.3 2.5 0.0047 16.6 0.2 3.4 4 0 0 4 4 3 2 SRP54-type protein, GTPase domain APS_kinase PF01583.20 AMK75581.1 - 5.1e-06 26.5 0.0 0.039 13.8 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase NACHT PF05729.12 AMK75581.1 - 1.1e-05 25.4 1.7 0.0019 18.1 0.2 2.9 2 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 AMK75581.1 - 4.2e-05 23.4 3.3 0.0071 16.1 0.2 3.2 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 AMK75581.1 - 8.4e-05 21.9 0.2 0.062 12.5 0.1 2.3 2 0 0 2 2 2 2 NB-ARC domain RuvB_N PF05496.12 AMK75581.1 - 9.7e-05 22.2 0.4 0.032 14.0 0.1 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AMK75581.1 - 0.0001 22.8 2.3 0.034 14.6 0.4 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AMK75581.1 - 0.00011 22.3 0.3 0.0045 17.1 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AMK75581.1 - 0.0002 21.9 0.3 0.0082 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AMK75581.1 - 0.00029 21.1 0.1 0.029 14.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AMK75581.1 - 0.00035 19.9 2.4 0.12 11.6 0.1 2.7 3 0 0 3 3 2 2 Zeta toxin RsgA_GTPase PF03193.16 AMK75581.1 - 0.0006 19.7 0.1 0.14 12.1 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 AMK75581.1 - 0.00096 19.0 1.2 0.72 9.6 0.0 2.6 3 0 0 3 3 2 2 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 AMK75581.1 - 0.0014 18.6 1.4 0.39 10.6 0.1 3.0 3 0 0 3 3 3 1 NTPase AAA_5 PF07728.14 AMK75581.1 - 0.0017 18.4 0.2 0.075 13.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MipZ PF09140.11 AMK75581.1 - 0.0023 17.3 1.9 0.76 9.0 0.1 3.0 4 0 0 4 4 4 1 ATPase MipZ Mg_chelatase PF01078.21 AMK75581.1 - 0.0029 17.0 0.6 0.068 12.5 0.4 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 AMK75581.1 - 0.0055 16.4 0.2 1 9.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain PIF1 PF05970.14 AMK75581.1 - 0.0074 15.5 0.0 1.9 7.6 0.0 2.5 3 0 0 3 3 2 1 PIF1-like helicase AAA_24 PF13479.6 AMK75581.1 - 0.0096 15.7 0.4 0.78 9.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain MobB PF03205.14 AMK75581.1 - 0.01 15.7 0.5 0.21 11.5 0.0 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 AMK75581.1 - 0.016 14.5 0.1 3 7.1 0.0 2.7 2 1 0 2 2 2 0 KaiC ABC_tran PF00005.27 AMK75581.1 - 0.019 15.5 0.1 0.38 11.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Ploopntkinase3 PF18751.1 AMK75581.1 - 0.019 14.9 0.2 0.98 9.3 0.1 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 AMK75581.1 - 0.027 14.8 0.0 0.97 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 AMK75581.1 - 0.034 14.1 0.3 0.63 10.0 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 AMK75581.1 - 0.044 13.3 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Spore_GerQ PF09671.10 AMK75581.1 - 0.047 13.7 0.0 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) Roc PF08477.13 AMK75581.1 - 0.05 13.8 0.5 2.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AMK75581.1 - 0.052 14.0 0.1 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 AMK75581.1 - 0.056 13.1 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase VirC1 PF07015.11 AMK75581.1 - 0.059 12.7 1.1 6.7 5.9 0.1 2.7 2 0 0 2 2 2 0 VirC1 protein PduV-EutP PF10662.9 AMK75581.1 - 0.064 13.0 0.9 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KTI12 PF08433.10 AMK75581.1 - 0.081 12.4 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 LpxK PF02606.14 AMK75581.1 - 0.082 12.0 2.3 6.5 5.8 0.0 2.5 3 0 0 3 3 2 0 Tetraacyldisaccharide-1-P 4'-kinase DUF2868 PF11067.8 AMK75581.1 - 0.091 12.3 6.1 1 8.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) TIP49 PF06068.13 AMK75581.1 - 0.098 11.8 0.2 2.3 7.4 0.1 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Sigma54_activat PF00158.26 AMK75581.1 - 0.12 12.1 0.1 3.3 7.4 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 AMK75581.1 - 0.12 12.4 0.3 1.3 9.1 0.1 2.9 3 1 0 3 3 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 AMK75581.1 - 0.18 11.0 0.1 4.5 6.4 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 AMK75581.1 - 0.2 11.9 2.8 0.35 11.1 0.1 2.8 2 1 1 3 3 2 0 AAA domain Glyoxalase PF00903.25 AMK75582.1 - 0.00044 20.4 0.0 0.003 17.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AMK75582.1 - 0.0028 17.9 0.0 0.28 11.5 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SBF PF01758.16 AMK75583.1 - 3.2e-66 222.7 11.8 3.2e-66 222.7 11.8 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family KASH PF10541.9 AMK75583.1 - 0.32 11.3 0.2 0.32 11.3 0.2 2.9 3 0 0 3 3 3 0 Nuclear envelope localisation domain Complex1_51K PF01512.17 AMK75586.1 - 1.2e-40 138.9 0.0 1.1e-39 135.8 0.0 2.2 3 0 0 3 3 3 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit 2Fe-2S_thioredx PF01257.19 AMK75586.1 - 8.7e-33 113.2 0.0 1.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NADH_4Fe-4S PF10589.9 AMK75586.1 - 1.5e-25 89.1 0.1 4.7e-25 87.5 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AMK75586.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 SLBB domain Fer4_15 PF13459.6 AMK75587.1 - 2.3e-13 50.7 0.2 5.6e-13 49.4 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer2_4 PF13510.6 AMK75587.1 - 2.8e-13 49.7 0.1 7.6e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 AMK75587.1 - 3.8e-11 42.3 1.1 3.8e-11 42.3 1.1 2.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 AMK75587.1 - 5.3e-08 32.7 1.7 5.9e-08 32.5 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AMK75587.1 - 0.0003 20.5 8.4 0.0019 17.9 0.6 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 AMK75587.1 - 0.0017 18.9 0.5 0.0071 16.9 0.5 2.1 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer2_3 PF13085.6 AMK75587.1 - 0.13 12.3 0.6 0.26 11.3 0.6 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 AMK75587.1 - 2.4 8.8 10.9 5.2 7.7 6.0 3.2 2 2 1 3 3 3 0 4Fe-4S dicluster domain zf-FPG_IleRS PF06827.14 AMK75587.1 - 6.2 6.8 7.2 6.8 6.6 0.2 3.4 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Oxidored_q6 PF01058.22 AMK75588.1 - 1.4e-28 99.3 0.0 1.7e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFeSe_Hases PF00374.19 AMK75589.1 - 1.8e-34 119.5 0.1 1.2e-16 60.8 0.0 3.1 2 1 0 3 3 3 3 Nickel-dependent hydrogenase Complex1_49kDa PF00346.19 AMK75589.1 - 0.011 14.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Vps53_N PF04100.12 AMK75591.1 - 0.0077 15.2 0.3 0.38 9.7 0.0 2.1 1 1 1 2 2 2 2 Vps53-like, N-terminal PhoU_div PF01865.16 AMK75591.1 - 0.012 14.9 2.1 0.021 14.2 1.6 1.5 1 1 0 2 2 2 0 Protein of unknown function DUF47 FtsX_ECD PF18075.1 AMK75591.1 - 0.018 15.7 0.6 2.6 8.7 0.1 2.7 2 1 1 3 3 3 0 FtsX extracellular domain DUF2524 PF10732.9 AMK75591.1 - 0.019 15.3 1.2 0.13 12.6 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) PHO4 PF01384.20 AMK75592.1 - 4.4e-87 292.3 36.6 6.8e-87 291.7 36.6 1.3 1 1 0 1 1 1 1 Phosphate transporter family DUF1495 PF07381.11 AMK75592.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) VPDSG-CTERM PF18205.1 AMK75594.1 - 0.078 12.8 1.0 0.27 11.1 1.0 2.0 1 0 0 1 1 1 0 VPDSG-CTERM motif PEP-CTERM PF07589.11 AMK75594.1 - 2 8.6 6.3 0.13 12.4 1.0 1.9 2 0 0 2 2 2 0 PEP-CTERM motif DUF839 PF05787.13 AMK75595.1 - 2.5e-17 63.2 9.5 1e-15 58.0 1.2 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF839) PEP-CTERM PF07589.11 AMK75595.1 - 0.022 14.8 1.2 0.022 14.8 1.2 2.0 2 0 0 2 2 2 0 PEP-CTERM motif VPDSG-CTERM PF18205.1 AMK75595.1 - 0.16 11.8 0.8 0.45 10.4 0.8 1.8 1 0 0 1 1 1 0 VPDSG-CTERM motif DDE_Tnp_1 PF01609.21 AMK75597.1 - 1.3e-14 54.4 2.2 4.7e-13 49.3 2.2 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AMK75597.1 - 4.6e-14 52.5 0.2 5.8e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK75597.1 - 3.2e-07 30.5 0.0 3.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK75597.1 - 9.2e-06 25.4 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 AMK75598.1 - 8.2e-16 58.3 0.0 2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_11 PF08279.12 AMK75598.1 - 0.00027 20.8 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AMK75598.1 - 0.00077 19.3 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 AMK75598.1 - 0.0025 17.6 0.0 0.02 14.7 0.0 2.4 3 0 0 3 3 3 1 HTH DNA binding domain HTH_DeoR PF08220.12 AMK75598.1 - 0.0077 15.9 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 AMK75598.1 - 0.012 15.6 0.2 0.07 13.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 AMK75598.1 - 0.021 14.6 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AMK75598.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AMK75598.1 - 0.052 13.6 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.16 AMK75598.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 NUMOD1 PF07453.13 AMK75598.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_41 PF14502.6 AMK75598.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AMK75598.1 - 0.1 12.4 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_23 PF13384.6 AMK75598.1 - 0.32 10.9 1.3 3 7.8 0.0 3.2 5 0 0 5 5 5 0 Homeodomain-like domain IstB_IS21 PF01695.17 AMK75599.1 - 6.6e-58 195.4 0.4 5.3e-57 192.4 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK75599.1 - 1.4e-09 38.1 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK75599.1 - 2e-05 24.2 0.1 2.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AFG1_ATPase PF03969.16 AMK75599.1 - 0.0024 16.8 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK75599.1 - 0.0073 16.0 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AMK75599.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 AMK75599.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AMK75599.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 AMK75599.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 AMK75599.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 AMK75599.1 - 0.029 14.3 1.8 1.2 9.1 0.0 2.7 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 AMK75599.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK75599.1 - 0.035 13.6 0.2 0.066 12.7 0.2 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 AMK75599.1 - 0.049 13.0 0.1 0.087 12.2 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 AMK75599.1 - 0.049 13.9 0.4 0.31 11.3 0.3 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AMK75599.1 - 0.058 13.1 0.3 0.12 12.1 0.3 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 AMK75599.1 - 0.13 11.6 0.1 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AMK75599.1 - 0.19 11.5 0.4 0.41 10.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK75599.1 - 0.35 11.2 1.7 0.99 9.7 1.1 2.0 1 1 1 2 2 2 0 AAA domain CobA_CobO_BtuR PF02572.15 AMK75599.1 - 0.68 10.2 3.7 6.3 7.0 1.6 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF4276 PF14103.6 AMK75600.1 - 1.8e-16 60.9 0.0 2.1e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4276) AAA_21 PF13304.6 AMK75601.1 - 1e-27 97.7 0.3 9.6e-27 94.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AMK75601.1 - 2.2e-23 83.6 0.3 1.2e-10 41.7 0.0 2.3 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AMK75601.1 - 1.4e-11 44.3 0.0 3e-07 30.1 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK75601.1 - 2e-06 28.4 0.4 4.2e-06 27.4 0.4 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK75601.1 - 8.2e-06 25.5 0.0 2.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 AMK75601.1 - 2.2e-05 23.9 0.0 0.00015 21.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_13 PF13166.6 AMK75601.1 - 0.00096 17.9 0.0 1.4 7.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_27 PF13514.6 AMK75601.1 - 0.0025 17.4 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK75601.1 - 0.01 16.4 0.1 0.024 15.1 0.1 1.8 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 AMK75601.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 AMK75601.1 - 0.19 11.0 0.0 0.61 9.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Methylase_S PF01420.19 AMK75602.1 - 2.3e-26 93.0 0.0 2.3e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain DUF1244 PF06844.11 AMK75602.1 - 0.17 12.0 0.2 0.49 10.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) EcoEI_R_C PF08463.10 AMK75603.1 - 1.2e-54 184.9 4.2 3.9e-54 183.3 1.0 2.8 3 0 0 3 3 3 1 EcoEI R protein C-terminal ResIII PF04851.15 AMK75603.1 - 7.9e-37 126.9 0.0 1.7e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AMK75603.1 - 7.8e-17 61.7 1.1 1.9e-16 60.4 0.1 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 AMK75603.1 - 7.3e-09 35.6 0.0 1e-06 28.6 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase HSDR_N PF04313.14 AMK75603.1 - 1e-06 28.8 0.1 8.6e-06 25.8 0.0 2.4 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Helicase_C PF00271.31 AMK75603.1 - 6.7e-05 23.2 0.2 0.00033 21.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF615 PF04751.14 AMK75603.1 - 0.073 13.0 3.6 0.67 9.9 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF615) HTH_38 PF13936.6 AMK75605.1 - 3.5e-15 55.5 4.3 5.3e-15 54.9 1.6 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.26 AMK75605.1 - 3.5e-12 46.5 0.0 8.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 AMK75605.1 - 2.2e-06 28.2 0.4 2.2e-06 28.2 0.4 2.8 4 0 0 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.6 AMK75605.1 - 0.00039 20.1 1.4 0.016 15.0 0.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve_3 PF13683.6 AMK75605.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain T3SS_needle_E PF08988.10 AMK75605.1 - 2.1 8.6 6.2 1.2 9.3 0.9 3.0 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF4300 PF14133.6 AMK75607.1 - 0.16 11.7 0.1 0.2 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) GED PF02212.18 AMK75608.1 - 0.014 15.5 1.3 1.8 8.8 0.1 2.9 3 0 0 3 3 3 0 Dynamin GTPase effector domain PDH PF02153.17 AMK75608.1 - 0.036 13.1 0.0 0.086 11.8 0.0 1.6 1 0 0 1 1 1 0 Prephenate dehydrogenase Cauli_AT PF03233.13 AMK75608.1 - 0.037 14.0 2.3 0.06 13.3 0.4 2.2 2 0 0 2 2 2 0 Aphid transmission protein DUF3997 PF13162.6 AMK75608.1 - 0.055 13.8 0.5 0.18 12.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Myosin_tail_1 PF01576.19 AMK75609.1 - 0.00033 18.7 4.0 0.00035 18.5 4.0 1.0 1 0 0 1 1 1 1 Myosin tail T3SSipB PF16535.5 AMK75609.1 - 0.0014 19.1 7.2 0.0019 18.7 7.2 1.3 1 0 0 1 1 1 1 Type III cell invasion protein SipB Syntaxin-6_N PF09177.11 AMK75609.1 - 0.0022 18.5 2.3 0.0043 17.6 2.3 1.6 1 1 0 1 1 1 1 Syntaxin 6, N-terminal PTS_IIA PF02255.16 AMK75609.1 - 0.0031 17.5 4.5 0.0055 16.7 4.5 1.4 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIA subunit DUF3646 PF12362.8 AMK75609.1 - 0.0035 17.6 1.4 0.0041 17.4 1.4 1.2 1 0 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal SLX9 PF15341.6 AMK75609.1 - 0.0046 17.4 4.0 0.0054 17.1 4.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Latarcin PF10279.9 AMK75609.1 - 0.0092 16.4 1.9 0.019 15.4 1.9 1.6 1 1 0 1 1 1 1 Latarcin precursor DUF2443 PF10398.9 AMK75609.1 - 0.014 15.5 1.9 0.045 13.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) XFP PF03894.15 AMK75609.1 - 0.026 14.3 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DUF3145 PF11343.8 AMK75609.1 - 0.041 13.4 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Sec5 PF15469.6 AMK75609.1 - 0.044 13.6 2.6 0.044 13.6 1.6 1.4 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF3435 PF11917.8 AMK75609.1 - 0.049 12.6 3.1 0.056 12.4 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF3987 PF13148.6 AMK75609.1 - 0.061 12.3 5.2 0.078 12.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ntox50 PF15542.6 AMK75609.1 - 0.075 13.8 0.2 0.12 13.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial toxin 50 KfrA_N PF11740.8 AMK75609.1 - 0.078 13.7 4.8 0.098 13.3 4.8 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term FapA PF03961.13 AMK75609.1 - 0.096 11.3 4.4 0.11 11.0 4.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ins134_P3_kin_N PF17927.1 AMK75609.1 - 0.1 13.0 0.1 0.14 12.5 0.1 1.4 1 1 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain UBN_AB PF14075.6 AMK75609.1 - 0.11 12.2 7.4 0.14 11.9 6.6 1.5 1 1 1 2 2 2 0 Ubinuclein conserved middle domain DUF5082 PF16888.5 AMK75609.1 - 0.19 12.0 8.2 0.072 13.4 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) AAA_13 PF13166.6 AMK75609.1 - 0.24 10.0 6.3 0.26 9.9 6.3 1.1 1 0 0 1 1 1 0 AAA domain 5_nucleotid PF05761.14 AMK75609.1 - 0.56 9.0 3.3 0.58 9.0 3.3 1.0 1 0 0 1 1 1 0 5' nucleotidase family DivIC PF04977.15 AMK75609.1 - 7.6 6.4 11.4 11 5.8 0.2 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF1566 PF07603.11 AMK75611.1 - 6.3e-10 39.4 0.0 7.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) Arylsulfotran_2 PF14269.6 AMK75612.1 - 0.00078 18.9 0.0 0.00086 18.8 0.0 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DsbC_N PF10411.9 AMK75612.1 - 0.15 11.5 0.1 0.33 10.4 0.1 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus DUF1566 PF07603.11 AMK75613.1 - 5.6e-09 36.4 0.0 1e-08 35.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1566) 4HB_MCP_1 PF12729.7 AMK75613.1 - 0.055 13.0 0.2 0.08 12.5 0.2 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Spc7 PF08317.11 AMK75613.1 - 0.2 10.5 0.6 0.28 10.0 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1566 PF07603.11 AMK75614.1 - 8.6e-08 32.6 0.0 1.4e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) Spc7 PF08317.11 AMK75614.1 - 0.044 12.7 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FANCI_HD1 PF14679.6 AMK75614.1 - 0.18 11.8 0.2 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 FANCI helical domain 1 DUF1566 PF07603.11 AMK75615.1 - 9.5e-08 32.4 0.0 1.1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) HTH_Tnp_1 PF01527.20 AMK75616.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK75616.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK75616.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75616.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK75616.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK75616.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK75617.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK75617.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK75617.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK75617.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK75617.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK75617.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK75617.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 AIF_C PF14721.6 AMK75618.1 - 0.0086 16.4 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DsbC_N PF10411.9 AMK75618.1 - 0.038 13.4 0.2 0.061 12.8 0.2 1.3 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus GRP PF07172.11 AMK75618.1 - 0.24 12.1 1.1 0.85 10.3 1.1 1.9 1 1 0 1 1 1 0 Glycine rich protein family DDE_Tnp_1 PF01609.21 AMK75620.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK75620.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK75620.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK75620.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK75620.1 - 0.0091 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK75620.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK75620.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK75620.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK75620.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK75620.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK75620.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK75620.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK75620.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain rve PF00665.26 AMK75621.1 - 2.3e-05 24.5 0.0 4.6e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 AMK75621.1 - 0.053 13.3 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain MACPF PF01823.19 AMK75622.1 - 5.7e-06 26.6 0.0 5.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 MAC/Perforin domain SAM_2 PF07647.17 AMK75622.1 - 0.0026 17.8 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IDEAL PF08858.10 AMK75622.1 - 0.14 11.9 0.9 0.36 10.6 0.9 1.7 1 0 0 1 1 1 0 IDEAL domain Effector_1 PF04518.12 AMK75622.1 - 0.2 10.7 4.3 0.083 12.0 1.5 1.8 2 0 0 2 2 2 0 Effector from type III secretion system Mit_KHE1 PF10173.9 AMK75622.1 - 0.98 9.5 5.3 0.2 11.7 1.6 1.6 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DarA_N PF18788.1 AMK75623.1 - 4.5e-35 120.0 3.7 7.6e-35 119.3 0.1 2.6 3 0 0 3 3 3 1 Defence against restriction A N-terminal Rx_N PF18052.1 AMK75623.1 - 0.0099 16.1 6.8 2.3 8.6 0.7 3.3 3 0 0 3 3 3 2 Rx N-terminal domain ABC_tran_CTD PF16326.5 AMK75623.1 - 0.011 15.9 10.5 11 6.3 4.4 3.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 AMK75623.1 - 0.014 15.4 3.7 1.5 8.8 0.2 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flg_hook PF02120.16 AMK75623.1 - 0.022 14.6 1.9 0.38 10.7 1.0 2.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Tropomyosin_1 PF12718.7 AMK75623.1 - 0.075 13.2 10.2 0.055 13.6 4.0 3.3 3 1 1 4 4 4 0 Tropomyosin like CCDC-167 PF15188.6 AMK75623.1 - 0.15 12.4 4.0 3.7 8.0 0.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 LUC7 PF03194.15 AMK75623.1 - 1.2 8.7 5.9 3.5 7.2 2.7 2.2 2 0 0 2 2 2 0 LUC7 N_terminus THOC7 PF05615.13 AMK75623.1 - 6.1 7.1 11.8 1 9.7 6.4 2.4 3 0 0 3 3 3 0 Tho complex subunit 7 DUF4140 PF13600.6 AMK75623.1 - 8.1 7.0 9.1 0.71 10.4 2.2 2.6 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_pRha PF09669.10 AMK75624.1 - 3.9e-12 46.6 0.0 6.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) IBN_N PF03810.19 AMK75624.1 - 0.054 13.4 0.6 2.6 8.0 0.2 2.6 2 1 0 2 2 2 0 Importin-beta N-terminal domain HTH_23 PF13384.6 AMK75625.1 - 0.032 14.0 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain ANAPC4 PF12896.7 AMK75625.1 - 0.056 12.9 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 HTH_23 PF13384.6 AMK75627.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_31 PF13560.6 AMK75628.1 - 7.5e-05 23.0 0.2 0.0004 20.7 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Phage_GPO PF05929.11 AMK75628.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase HTH_19 PF12844.7 AMK75628.1 - 0.027 14.5 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 AMK75629.1 - 8.5e-09 35.6 0.2 2.3e-08 34.3 0.1 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AMK75629.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AMK75629.1 - 5.8e-07 29.4 0.0 9.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AMK75629.1 - 0.00061 19.7 0.1 0.00099 19.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AMK75629.1 - 0.0036 17.1 0.1 0.0099 15.7 0.1 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 AMK75629.1 - 0.065 13.4 0.0 0.75 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AMK75629.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_lysozyme2 PF18013.1 AMK75631.1 - 7.7e-20 71.4 2.8 2e-19 70.0 2.8 1.7 1 0 0 1 1 1 1 Phage tail lysozyme Rick_17kDa_Anti PF05433.15 AMK75631.1 - 0.033 14.0 25.3 0.22 11.4 18.9 3.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain Phasin_2 PF09361.10 AMK75631.1 - 0.55 10.5 5.5 0.48 10.7 1.5 2.8 3 1 1 4 4 4 0 Phasin protein DUF456 PF04306.13 AMK75631.1 - 1.2 9.4 15.5 19 5.6 15.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF456) HlyD_2 PF12700.7 AMK75633.1 - 0.046 12.5 1.7 0.069 11.9 1.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein TPR_MalT PF17874.1 AMK75633.1 - 0.056 12.8 0.4 0.1 12.0 0.4 1.4 1 1 0 1 1 1 0 MalT-like TPR region DUF4015 PF13200.6 AMK75633.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain YCII PF03795.14 AMK75634.1 - 3.8e-20 72.1 0.0 4.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Lipase_3 PF01764.25 AMK75635.1 - 0.0016 18.4 0.8 0.015 15.2 0.2 2.4 2 1 1 3 3 3 1 Lipase (class 3) BAAT_C PF08840.11 AMK75635.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 AMK75635.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 AMK75635.1 - 0.0034 17.0 0.4 0.009 15.6 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 AMK75635.1 - 0.0035 16.6 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 AMK75635.1 - 0.0078 15.8 0.0 0.051 13.1 0.0 2.0 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Esterase PF00756.20 AMK75635.1 - 0.0093 15.6 0.0 0.089 12.4 0.0 2.0 1 1 1 2 2 2 1 Putative esterase PGAP1 PF07819.13 AMK75635.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 AMK75635.1 - 0.023 15.3 0.0 0.027 15.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 AMK75635.1 - 0.036 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 AMK75635.1 - 0.046 13.6 0.0 0.077 12.8 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 AMK75635.1 - 0.048 13.6 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) TPR_2 PF07719.17 AMK75636.1 - 3.3e-07 29.9 11.7 9.7e-05 22.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75636.1 - 0.0002 21.0 1.8 1.8 8.3 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 AMK75636.1 - 0.00026 20.7 3.8 0.41 10.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75636.1 - 0.027 15.3 0.6 53 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75636.1 - 0.15 12.7 0.9 43 4.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AMK75636.1 - 0.15 12.3 13.0 0.82 10.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK75636.1 - 0.55 10.2 5.2 3.8 7.5 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NYN PF01936.18 AMK75637.1 - 0.048 14.2 0.2 0.24 11.9 0.0 2.2 2 1 0 2 2 2 0 NYN domain PhaP_Bmeg PF09602.10 AMK75637.1 - 0.1 12.5 8.8 0.5 10.3 8.0 2.3 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FAM25 PF15825.5 AMK75637.1 - 0.19 12.1 6.0 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 FAM25 family PSD2 PF07624.11 AMK75638.1 - 0.085 12.6 0.4 0.19 11.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1585) HTH_3 PF01381.22 AMK75640.1 - 1.7e-06 28.0 0.2 5.7e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AMK75640.1 - 2.7e-06 27.3 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AMK75640.1 - 3.9e-06 26.7 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AMK75640.1 - 5.9e-05 23.3 0.0 8.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltr_RsmF_N PF17125.5 AMK75640.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF DsbD_2 PF13386.6 AMK75641.1 - 6.3e-38 130.7 31.1 7.6e-38 130.5 31.1 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DUF2157 PF09925.9 AMK75641.1 - 0.96 9.2 17.1 1.2 8.9 15.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF2627 PF11118.8 AMK75641.1 - 8.4 7.0 11.9 4.6 7.9 2.9 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2627) E1-E2_ATPase PF00122.20 AMK75642.1 - 6.7e-50 169.1 8.9 1.4e-49 168.1 4.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AMK75642.1 - 8.4e-50 170.0 3.3 1.4e-49 169.2 2.9 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AMK75642.1 - 3.7e-13 49.7 1.2 5.6e-12 45.9 0.3 2.9 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AMK75642.1 - 2e-07 31.0 1.2 0.00071 19.4 0.3 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK75642.1 - 0.00017 22.1 0.1 0.00087 19.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AMK75642.1 - 0.00095 19.2 0.0 0.044 13.9 0.0 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AMK75642.1 - 0.081 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HMA PF00403.26 AMK75643.1 - 0.014 15.8 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain CdiI PF07262.11 AMK75643.1 - 0.17 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 CDI immunity protein DUF5518 PF17647.1 AMK75644.1 - 0.047 13.8 0.2 0.058 13.5 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5518) DUF5132 PF17195.4 AMK75644.1 - 0.087 12.9 0.5 0.39 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) PAF-AH_p_II PF03403.13 AMK75644.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II SPC12 PF06645.13 AMK75645.1 - 0.15 12.2 0.2 0.23 11.6 0.2 1.3 1 1 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) AA_kinase PF00696.28 AMK75646.1 - 5.7e-51 173.4 2.1 8.7e-51 172.8 2.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 AMK75646.1 - 5.4e-21 74.1 1.2 1.3e-16 60.1 0.6 2.8 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 AMK75646.1 - 1e-18 66.8 2.9 5.8e-09 35.6 0.1 3.1 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 AMK75646.1 - 0.018 15.6 0.2 7.2 7.3 0.0 2.7 2 0 0 2 2 2 0 ACT domain DUF3335 PF11814.8 AMK75646.1 - 0.042 13.3 0.3 0.31 10.5 0.0 2.5 3 0 0 3 3 3 0 Peptidase_C39 like family Fe_hyd_lg_C PF02906.14 AMK75646.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF2007 PF09413.10 AMK75646.1 - 0.12 12.6 0.3 18 5.6 0.0 2.9 3 0 0 3 3 3 0 Putative prokaryotic signal transducing protein HicA_toxin PF07927.12 AMK75648.1 - 8.2e-11 41.8 0.0 9.1e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, ODR4-like PF14778.6 AMK75649.1 - 0.11 11.4 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Olfactory receptor 4-like tRNA-synt_2c PF01411.19 AMK75650.1 - 5.9e-219 728.2 0.0 7.4e-219 727.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AMK75650.1 - 1.8e-29 102.9 3.4 1.8e-29 102.9 3.4 1.9 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 AMK75650.1 - 9e-17 60.9 0.4 2.4e-16 59.5 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Ribosomal_L27 PF01016.19 AMK75650.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L27 protein Snapin_Pallidin PF14712.6 AMK75650.1 - 0.017 15.6 1.2 7.7 7.0 0.0 2.6 3 0 0 3 3 3 0 Snapin/Pallidin Laminin_II PF06009.12 AMK75650.1 - 0.052 13.6 1.9 0.54 10.3 1.2 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF1319 PF07028.11 AMK75650.1 - 0.21 11.8 0.5 0.68 10.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) EF-hand_6 PF13405.6 AMK75650.1 - 0.66 10.1 2.4 1 9.5 0.1 2.7 3 1 0 3 3 3 0 EF-hand domain CLZ PF16526.5 AMK75650.1 - 2 8.9 8.5 1.1 9.7 2.1 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RecX PF02631.16 AMK75651.1 - 1.7e-29 102.7 2.2 4.5e-28 98.1 0.6 1.7 1 1 1 2 2 2 2 RecX family DUF1421 PF07223.11 AMK75651.1 - 0.029 14.2 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Phg_2220_C PF09524.10 AMK75651.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) RecA PF00154.21 AMK75652.1 - 7.8e-146 484.5 4.0 9.4e-146 484.2 4.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AMK75652.1 - 9.4e-11 41.4 1.1 3.5e-10 39.6 1.1 1.7 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AMK75652.1 - 9.5e-07 28.4 4.0 4.1e-05 23.0 2.3 3.2 2 1 0 2 2 2 1 KaiC ATPase_2 PF01637.18 AMK75652.1 - 2.5e-06 27.6 0.0 6.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AMK75652.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AMK75652.1 - 0.0012 18.4 0.5 0.025 14.2 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK75652.1 - 0.0084 16.5 0.5 0.013 15.9 0.1 1.4 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 AMK75652.1 - 0.012 16.1 0.1 0.025 15.0 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CobU PF02283.16 AMK75652.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_35 PF14516.6 AMK75652.1 - 0.049 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.6 AMK75652.1 - 0.069 13.2 0.1 0.65 10.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 AMK75652.1 - 0.071 13.0 0.1 0.36 10.7 0.0 2.1 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B GATase_3 PF07685.14 AMK75653.1 - 6.2e-35 120.6 0.0 8.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AMK75653.1 - 6.1e-13 48.9 0.0 9.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AMK75653.1 - 1.9e-09 37.6 0.0 0.00031 20.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain SNO PF01174.19 AMK75653.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Paired_CXXCH_1 PF09699.10 AMK75654.1 - 0.083 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Haem_bd PF14376.6 AMK75654.1 - 0.29 11.1 1.3 3.8 7.5 0.4 2.5 2 1 0 2 2 2 0 Haem-binding domain RelA_SpoT PF04607.17 AMK75656.1 - 6.6e-38 129.6 0.0 1.5e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 AMK75656.1 - 7.6e-37 126.4 1.4 1.8e-36 125.2 1.4 1.7 1 0 0 1 1 1 1 HD domain TGS PF02824.21 AMK75656.1 - 3.4e-20 71.9 0.0 8e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AMK75656.1 - 1.3e-14 54.5 2.1 1.3e-14 54.5 2.1 2.2 2 0 0 2 2 2 1 ACT domain eIF-1a PF01176.19 AMK75657.1 - 7.8e-28 96.1 0.1 8.7e-28 95.9 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 AMK75657.1 - 4.7e-05 23.1 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain S1 PF00575.23 AMK75657.1 - 0.026 14.8 0.1 0.032 14.6 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain RNase_II_C_S1 PF18614.1 AMK75657.1 - 0.045 13.7 0.0 0.082 12.9 0.0 1.7 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain CSD2 PF17876.1 AMK75657.1 - 0.1 12.8 0.1 4.1 7.7 0.0 2.5 1 1 2 3 3 3 0 Cold shock domain AAA_2 PF07724.14 AMK75658.1 - 4e-52 176.8 0.0 9.1e-49 165.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AMK75658.1 - 4e-28 97.4 0.9 1.1e-27 96.0 0.9 1.8 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AMK75658.1 - 4.6e-25 88.6 0.2 1.6e-12 48.0 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AMK75658.1 - 1.7e-22 79.3 0.0 7.6e-22 77.2 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AMK75658.1 - 5.2e-19 68.6 0.0 7.3e-13 48.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK75658.1 - 1.6e-13 51.4 2.9 2.2e-06 28.1 0.1 4.2 3 1 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 AMK75658.1 - 8.9e-12 45.0 0.2 7.1e-05 22.6 0.1 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain Clp_N PF02861.20 AMK75658.1 - 2e-10 40.7 0.1 1.7e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 AMK75658.1 - 3.4e-08 33.9 4.7 0.0091 16.3 0.3 4.7 3 3 0 3 3 3 2 AAA domain AAA_7 PF12775.7 AMK75658.1 - 3.3e-07 30.0 0.0 0.019 14.5 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 AMK75658.1 - 8.6e-07 29.6 0.0 0.04 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 AMK75658.1 - 1.2e-06 28.1 0.0 0.0021 17.5 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 AMK75658.1 - 2.1e-06 27.8 0.0 0.011 15.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 AMK75658.1 - 3.5e-06 26.5 0.1 1.6 8.0 0.0 3.6 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AMK75658.1 - 9.6e-06 25.4 4.1 0.25 11.1 0.2 4.5 3 2 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AMK75658.1 - 1.7e-05 24.8 0.1 0.06 13.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 AMK75658.1 - 2.4e-05 24.2 0.0 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_6 PF12774.7 AMK75658.1 - 2.7e-05 23.3 0.1 0.00011 21.2 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 AMK75658.1 - 5.2e-05 23.1 0.1 0.0025 17.7 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AMK75658.1 - 0.00011 22.4 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 AMK75658.1 - 0.00012 21.4 0.2 0.01 15.1 0.0 2.5 2 1 1 3 3 3 1 TIP49 P-loop domain ResIII PF04851.15 AMK75658.1 - 0.00021 21.3 0.2 0.56 10.2 0.0 3.3 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 AMK75658.1 - 0.00035 20.9 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 AMK75658.1 - 0.0012 18.8 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AMK75658.1 - 0.0033 17.3 0.6 4.8 7.1 0.1 3.5 3 1 1 4 4 4 0 RsgA GTPase SRP54 PF00448.22 AMK75658.1 - 0.0038 16.9 0.1 3.5 7.2 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 AMK75658.1 - 0.0045 16.9 0.3 0.088 12.7 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.6 AMK75658.1 - 0.022 14.4 0.9 5.6 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 AMK75658.1 - 0.024 13.9 0.0 4 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 AMK75658.1 - 0.032 13.9 0.5 2.1 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain SpoVIF PF14069.6 AMK75658.1 - 0.057 13.2 0.5 0.19 11.5 0.5 1.9 1 0 0 1 1 1 0 Stage VI sporulation protein F TDP43_N PF18694.1 AMK75658.1 - 0.057 13.3 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 1 0 Transactive response DNA-binding protein N-terminal domain AAA_28 PF13521.6 AMK75658.1 - 0.057 13.7 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AMK75658.1 - 0.06 13.3 0.0 27 4.6 0.0 3.2 3 0 0 3 3 3 0 NTPase Cytidylate_kin PF02224.18 AMK75658.1 - 0.062 13.0 0.2 2.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase DNA_pol3_delta2 PF13177.6 AMK75658.1 - 0.062 13.1 0.0 8.8 6.1 0.0 3.1 3 0 0 3 3 2 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 AMK75658.1 - 0.086 12.6 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 AMK75658.1 - 0.088 13.1 1.3 18 5.6 0.0 3.4 2 1 1 3 3 3 0 AAA domain SKI PF01202.22 AMK75658.1 - 0.095 12.8 0.2 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Roc PF08477.13 AMK75658.1 - 0.1 12.9 0.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IPT PF01745.16 AMK75658.1 - 0.1 12.0 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.11 AMK75658.1 - 0.12 12.4 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.6 AMK75658.1 - 0.12 12.0 0.0 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 AMK75658.1 - 0.22 11.4 4.1 18 5.2 0.1 3.8 4 1 1 5 5 3 0 ATPase domain predominantly from Archaea ClpS PF02617.17 AMK75659.1 - 3e-34 116.7 0.4 3.5e-34 116.4 0.4 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Stealth_CR4 PF17103.5 AMK75659.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 NUDIX PF00293.28 AMK75660.1 - 1.8e-13 50.7 0.4 2.3e-13 50.3 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA_Me_trans PF03054.16 AMK75661.1 - 2.1e-138 461.0 0.0 2.3e-138 460.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 AMK75661.1 - 1.5e-06 27.5 0.0 4.4e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 AMK75661.1 - 3.3e-05 23.7 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AMK75661.1 - 0.00073 19.1 0.0 0.0093 15.5 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 AMK75661.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 AMK75661.1 - 0.14 11.9 0.1 0.43 10.3 0.0 1.8 2 1 0 2 2 2 0 PP-loop family Lyase_1 PF00206.20 AMK75662.1 - 1.8e-67 228.0 0.0 2.2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 AMK75662.1 - 6.7e-52 174.5 0.1 2.7e-51 172.5 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Gate PF07670.14 AMK75663.1 - 2.2e-14 53.7 15.7 6.3e-11 42.5 0.3 3.4 3 1 0 3 3 3 2 Nucleoside recognition COX2_TM PF02790.15 AMK75663.1 - 0.01 16.0 1.9 5.7 7.1 0.1 3.0 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain SLATT_fungal PF18142.1 AMK75663.1 - 0.11 12.5 5.4 0.051 13.6 1.5 2.4 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Radical_SAM PF04055.21 AMK75664.1 - 3.3e-23 82.9 0.0 6.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AMK75664.1 - 3.7e-22 78.2 0.4 8.1e-22 77.1 0.4 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 B12-binding PF02310.19 AMK75664.1 - 0.0034 17.4 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Met_gamma_lyase PF06838.11 AMK75664.1 - 0.061 11.8 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase MlaA PF04333.13 AMK75665.1 - 2e-72 243.0 0.0 2.4e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 MlaA lipoprotein Phosphoesterase PF04185.14 AMK75665.1 - 0.1 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoesterase family RNase_T PF00929.24 AMK75666.1 - 8e-30 104.5 0.1 9.4e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AMK75666.1 - 2.4e-10 40.7 0.0 1.1e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 AMK75666.1 - 0.022 14.8 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily Glutaredoxin PF00462.24 AMK75667.1 - 4.2e-20 71.7 0.0 5.3e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AMK75667.1 - 0.00096 19.5 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Epimerase PF01370.21 AMK75668.1 - 1e-71 241.2 0.1 1.2e-71 241.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK75668.1 - 3.2e-23 82.7 0.3 9.8e-22 77.8 0.0 2.1 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AMK75668.1 - 1.8e-07 30.6 0.0 5.5e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AMK75668.1 - 0.00032 19.9 0.5 0.002 17.3 0.1 2.4 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein Antibiotic_NAT PF02522.14 AMK75668.1 - 0.026 14.4 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase GDP_Man_Dehyd PF16363.5 AMK75669.1 - 9.7e-158 524.8 0.0 1.1e-157 524.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AMK75669.1 - 4.2e-74 249.0 0.0 5.2e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 AMK75669.1 - 1.9e-07 30.5 0.0 3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AMK75669.1 - 0.00059 19.1 0.0 0.00088 18.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 AMK75669.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Exosortase_EpsH PF09721.10 AMK75670.1 - 3.2e-64 216.9 26.6 4.8e-64 216.4 26.6 1.2 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF3485 PF11984.8 AMK75670.1 - 1.1e-53 182.0 0.0 1.6e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3485) PUA_3 PF17785.1 AMK75672.1 - 1.2e-19 69.9 0.0 2.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain Methyltrans_SAM PF10672.9 AMK75672.1 - 2.3e-18 66.3 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AMK75672.1 - 9.3e-11 41.7 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 AMK75672.1 - 2e-10 40.7 0.0 5.4e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AMK75672.1 - 2.9e-09 36.7 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 AMK75672.1 - 4.2e-09 36.2 0.0 6.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 AMK75672.1 - 7.3e-09 35.7 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 AMK75672.1 - 6.4e-06 26.8 0.9 7.8e-05 23.3 0.1 2.6 2 1 1 3 3 3 1 Methyltransferase domain UPF0020 PF01170.18 AMK75672.1 - 0.00038 20.2 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TRM PF02005.16 AMK75672.1 - 0.00043 19.6 0.0 0.00055 19.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 AMK75672.1 - 0.00053 19.5 0.0 0.00082 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 AMK75672.1 - 0.026 14.2 0.0 0.24 11.0 0.0 2.3 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_16 PF10294.9 AMK75672.1 - 0.028 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Spermine_synth PF01564.17 AMK75672.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_24 PF13578.6 AMK75672.1 - 0.082 13.9 0.1 0.28 12.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75672.1 - 0.11 13.2 0.2 0.41 11.4 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase domain AAA_31 PF13614.6 AMK75672.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3426 PF11906.8 AMK75673.1 - 3.7e-29 101.8 0.3 5.4e-29 101.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) zinc_ribbon_4 PF13717.6 AMK75673.1 - 2.6e-07 30.4 0.6 4.2e-07 29.8 0.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AMK75673.1 - 0.00091 19.1 2.8 0.0016 18.4 2.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Cys_rich_CPXG PF14255.6 AMK75673.1 - 0.0015 18.4 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 Cysteine-rich CPXCG Zn-ribbon_8 PF09723.10 AMK75673.1 - 0.0023 18.0 1.2 0.098 12.8 0.0 2.4 2 0 0 2 2 2 1 Zinc ribbon domain Elf1 PF05129.13 AMK75673.1 - 0.013 15.6 0.2 0.024 14.6 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 AMK75673.1 - 0.12 11.8 0.9 17 5.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ISL3 PF14690.6 AMK75673.1 - 0.13 12.9 2.0 0.37 11.5 1.7 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PrmA PF06325.13 AMK75674.1 - 6.1e-86 288.5 0.0 6.8e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 AMK75674.1 - 4.7e-09 36.0 0.0 7.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 AMK75674.1 - 5.8e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK75674.1 - 7.8e-07 29.0 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75674.1 - 5.5e-05 23.8 0.0 0.00013 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AMK75674.1 - 7.2e-05 22.8 0.1 0.00019 21.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AMK75674.1 - 8.7e-05 22.2 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 AMK75674.1 - 0.0002 21.9 0.0 0.00039 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75674.1 - 0.0005 20.8 0.0 0.00099 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 AMK75674.1 - 0.00089 18.3 0.1 0.0015 17.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 AMK75674.1 - 0.0051 16.4 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 AMK75674.1 - 0.0096 15.6 0.3 0.038 13.7 0.3 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 AMK75674.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 AMK75674.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 AMK75674.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CPSase_L_D2 PF02786.17 AMK75675.1 - 3.7e-85 284.7 0.1 6.4e-85 283.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AMK75675.1 - 6.9e-46 155.3 0.1 2.3e-45 153.7 0.1 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AMK75675.1 - 2.7e-38 130.4 0.0 5.7e-38 129.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AMK75675.1 - 1.6e-08 34.4 0.0 4e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AMK75675.1 - 1.6e-06 27.8 0.1 3.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AMK75675.1 - 7.6e-06 26.1 0.0 1.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 AMK75675.1 - 0.085 13.4 0.1 27 5.4 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp N-terminal domain Biotin_lipoyl PF00364.22 AMK75676.1 - 9.6e-24 83.0 0.3 2.6e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AMK75676.1 - 1.6e-09 37.4 0.6 9.2e-06 25.4 0.0 3.4 3 2 1 4 4 4 2 Biotin-lipoyl like GCV_H PF01597.19 AMK75676.1 - 0.022 14.7 2.6 0.13 12.1 0.1 2.6 1 1 0 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.6 AMK75676.1 - 0.024 14.6 2.5 0.11 12.5 0.2 2.4 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AMK75676.1 - 0.043 13.0 0.0 1.2 8.3 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK75676.1 - 0.057 14.1 0.1 0.6 10.8 0.0 2.5 3 0 0 3 3 3 0 HlyD family secretion protein Rieske_2 PF13806.6 AMK75676.1 - 0.066 13.1 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain DHquinase_II PF01220.19 AMK75677.1 - 6.7e-60 200.7 0.3 7.7e-60 200.5 0.3 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Peripla_BP_4 PF13407.6 AMK75677.1 - 4.6e-05 23.1 0.0 6.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain PrpR_N PF06506.11 AMK75677.1 - 0.0019 17.8 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Propionate catabolism activator Peripla_BP_1 PF00532.21 AMK75677.1 - 0.017 14.6 0.2 0.029 13.8 0.2 1.3 1 1 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Glu_syn_central PF04898.14 AMK75677.1 - 0.083 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain Redoxin PF08534.10 AMK75678.1 - 1.7e-22 79.8 0.0 2.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AMK75678.1 - 7.5e-21 74.3 0.0 1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AMK75678.1 - 3.4e-10 40.1 0.0 5.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AMK75678.1 - 6.7e-08 32.5 0.2 4.8e-07 29.7 0.1 1.9 1 1 0 2 2 2 1 Thioredoxin GSHPx PF00255.19 AMK75678.1 - 0.0071 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_2 PF13098.6 AMK75678.1 - 0.0076 16.7 0.0 0.017 15.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain T4_deiodinase PF00837.17 AMK75678.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Iodothyronine deiodinase Thioredoxin_9 PF14595.6 AMK75678.1 - 0.023 14.5 0.5 0.26 11.1 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin AhpC-TSA_2 PF13911.6 AMK75678.1 - 0.057 13.5 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 AMK75678.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC DsbC PF11412.8 AMK75679.1 - 3.6e-64 214.2 1.0 1.1e-31 109.4 0.1 2.3 2 0 0 2 2 2 2 Disulphide bond corrector protein DsbC DsbD PF02683.15 AMK75679.1 - 1.6e-18 67.4 15.0 1.6e-18 67.4 15.0 2.2 1 1 1 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_7 PF13899.6 AMK75679.1 - 5.5e-12 45.7 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AMK75679.1 - 1.3e-08 34.8 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AMK75679.1 - 4e-08 33.7 0.0 7.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DsbD_2 PF13386.6 AMK75679.1 - 1.6e-06 28.2 21.6 1.6e-06 28.2 21.6 2.9 1 1 2 3 3 3 1 Cytochrome C biogenesis protein transmembrane region Thioredox_DsbH PF03190.15 AMK75679.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 YbhQ PF11076.8 AMK75679.1 - 0.25 11.4 2.6 0.64 10.0 2.6 1.7 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ PsbX PF06596.11 AMK75679.1 - 8.1 6.5 8.9 0.25 11.4 1.1 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) CutA1 PF03091.15 AMK75680.1 - 1.3e-38 130.8 0.0 1.5e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein FxsA PF04186.13 AMK75681.1 - 1.7e-36 124.6 7.2 2.7e-36 124.0 7.2 1.3 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein DUF2892 PF11127.8 AMK75682.1 - 1.5e-14 53.7 0.1 1.9e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) DUF4491 PF14898.6 AMK75682.1 - 0.011 16.1 0.1 0.015 15.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) UvrD-helicase PF00580.21 AMK75683.1 - 5.1e-79 266.0 1.3 5.1e-79 266.0 1.3 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AMK75683.1 - 2.5e-71 240.9 0.4 7.4e-71 239.3 0.0 2.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AMK75683.1 - 4.1e-33 114.8 0.0 1e-32 113.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AMK75683.1 - 2.2e-08 33.8 0.0 6e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AMK75683.1 - 3.6e-08 33.4 0.0 0.00043 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AMK75683.1 - 6.2e-05 22.8 0.0 0.15 11.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Exonuc_V_gamma PF04257.14 AMK75683.1 - 0.00011 20.6 0.2 0.00021 19.7 0.2 1.4 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit Terminase_6 PF03237.15 AMK75683.1 - 0.11 12.2 0.3 3.8 7.1 0.0 3.1 5 0 0 5 5 5 0 Terminase-like family PK PF00224.21 AMK75684.1 - 1.6e-118 395.6 6.5 1.9e-118 395.3 6.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 AMK75684.1 - 3e-27 95.2 0.0 2.5e-26 92.2 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 AMK75684.1 - 0.011 14.7 0.1 0.063 12.3 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Gp_dh_C PF02800.20 AMK75685.1 - 2.2e-61 206.1 0.0 3.1e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AMK75685.1 - 2.2e-39 133.8 0.1 4.3e-39 132.9 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 AMK75685.1 - 0.0073 16.4 0.2 0.019 15.1 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 AMK75685.1 - 0.042 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 AMK75685.1 - 0.07 14.0 0.0 0.19 12.5 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 AMK75685.1 - 0.077 13.6 0.2 0.23 12.1 0.0 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MMR_HSR1 PF01926.23 AMK75686.1 - 3.1e-15 56.3 0.1 3.2e-14 53.0 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AMK75686.1 - 1e-07 31.6 2.3 1.9e-06 27.5 0.4 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AMK75686.1 - 1.1e-06 28.6 0.8 3.3e-06 27.1 0.8 1.8 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 AMK75686.1 - 0.0004 20.5 0.0 0.21 11.7 0.1 2.6 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.9 AMK75686.1 - 0.0012 18.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 AMK75686.1 - 0.014 16.0 0.2 0.043 14.3 0.1 1.9 1 1 1 2 2 2 0 ABC transporter Arf PF00025.21 AMK75686.1 - 0.014 14.8 0.4 0.035 13.6 0.2 1.8 1 1 1 2 2 2 0 ADP-ribosylation factor family ATP_bind_1 PF03029.17 AMK75686.1 - 0.02 14.7 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MTS PF05175.14 AMK75687.1 - 3.6e-10 39.6 0.0 4.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AMK75687.1 - 1.2e-09 38.1 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 AMK75687.1 - 2.3e-08 34.0 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75687.1 - 1e-07 32.5 0.0 1.7e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75687.1 - 5.3e-07 30.2 0.0 9.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75687.1 - 6.5e-07 29.3 0.0 9.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AMK75687.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 AMK75687.1 - 0.001 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75687.1 - 0.0027 18.4 0.0 0.0048 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AMK75687.1 - 0.006 16.2 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 AMK75687.1 - 0.0077 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 AMK75687.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 AMK75687.1 - 0.033 13.9 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 AMK75687.1 - 0.093 12.4 0.0 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Cupin_7 PF12973.7 AMK75688.1 - 0.00042 20.2 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 AMK75688.1 - 0.018 14.7 0.3 0.027 14.2 0.3 1.3 1 0 0 1 1 1 0 Cupin domain NadA PF02445.16 AMK75690.1 - 1.1e-103 346.5 0.9 1.3e-103 346.3 0.9 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein Ins134_P3_kin_N PF17927.1 AMK75690.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain DUF2780 PF11075.8 AMK75692.1 - 4.6e-39 134.4 8.0 5.3e-39 134.2 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) Zip PF02535.22 AMK75693.1 - 3.9e-20 72.4 29.6 6e-20 71.7 14.2 2.4 2 1 1 3 3 3 2 ZIP Zinc transporter UPF0016 PF01169.19 AMK75694.1 - 3e-41 139.6 22.0 1.5e-21 76.5 6.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 AMK75694.1 - 0.0043 16.7 18.8 0.037 13.7 4.9 2.2 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE TerC PF03741.16 AMK75694.1 - 0.01 15.6 5.8 0.019 14.6 0.2 2.1 1 1 0 2 2 2 0 Integral membrane protein TerC family DUF4191 PF13829.6 AMK75694.1 - 0.74 9.1 3.1 0.49 9.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4131 PF13567.6 AMK75694.1 - 1.9 8.1 8.5 0.23 11.1 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MASE1 PF05231.14 AMK75695.1 - 4.7e-37 127.8 33.0 7.7e-37 127.0 33.0 1.3 1 0 0 1 1 1 1 MASE1 PAS_4 PF08448.10 AMK75695.1 - 5.9e-17 61.9 0.0 2.6e-10 40.5 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 AMK75695.1 - 2.4e-14 53.3 0.0 8.6e-05 22.5 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 AMK75695.1 - 8.8e-14 51.1 0.2 1.8e-06 27.8 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_9 PF13426.7 AMK75695.1 - 2.9e-13 50.0 0.0 8e-06 26.1 0.0 2.6 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 AMK75695.1 - 1.5e-07 31.6 0.0 0.00023 21.4 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_7 PF12860.7 AMK75695.1 - 5.1e-05 23.4 0.1 0.0052 16.9 0.0 3.3 3 1 0 3 3 3 1 PAS fold Phage_holin_2_3 PF16080.5 AMK75695.1 - 1.3 8.8 3.5 3.5 7.4 0.1 2.7 3 0 0 3 3 3 0 Bacteriophage holin family HP1 EAL PF00563.20 AMK75696.1 - 1.8e-74 250.3 0.0 2.7e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK75696.1 - 4.9e-58 195.4 0.1 9.4e-58 194.5 0.1 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AMK75696.1 - 2.7e-29 101.6 0.0 1.2e-17 64.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AMK75696.1 - 9.3e-25 86.8 0.0 4.7e-16 58.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AMK75696.1 - 3.7e-24 85.0 0.0 3.5e-15 56.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AMK75696.1 - 1.4e-14 53.7 0.1 1.5e-06 28.0 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AMK75696.1 - 1.3e-11 44.6 0.1 3.5e-09 36.8 0.0 3.6 4 0 0 4 4 4 1 PAS fold PAS_7 PF12860.7 AMK75696.1 - 3.6e-05 23.9 0.0 0.089 13.0 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_10 PF13596.6 AMK75696.1 - 0.065 13.8 0.0 0.26 11.9 0.0 2.1 2 0 0 2 2 2 0 PAS domain PAS_12 PF18095.1 AMK75696.1 - 0.097 12.3 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain DNA_pol_A_exo1 PF01612.20 AMK75697.1 - 1.4e-36 125.8 0.0 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 AMK75697.1 - 1.6e-15 56.9 0.5 7e-15 54.8 0.1 2.3 2 0 0 2 2 2 1 HRDC domain HTH_15 PF12324.8 AMK75697.1 - 0.17 11.9 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase TonB_dep_Rec PF00593.24 AMK75698.1 - 2.9e-46 159.3 30.0 2.9e-46 159.3 30.0 2.2 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK75698.1 - 2.1e-15 57.2 2.9 2.1e-15 57.2 0.4 2.4 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain DbpA PF03880.15 AMK75699.1 - 1.3e-15 57.2 0.0 2.2e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain Rotamase_3 PF13616.6 AMK75700.1 - 1.4e-50 170.7 0.2 1.4e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 PPIC-type PPIASE domain Rotamase PF00639.21 AMK75700.1 - 2.2e-50 169.6 0.0 5.8e-25 88.1 0.0 2.8 2 0 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 AMK75700.1 - 8.9e-37 125.8 5.7 8.9e-37 125.8 5.7 2.0 2 0 0 2 2 2 1 SurA N-terminal domain Rotamase_2 PF13145.6 AMK75700.1 - 7e-17 62.4 0.2 3.1e-07 31.2 0.0 2.9 3 1 0 3 3 3 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AMK75700.1 - 8e-16 58.2 0.6 8e-16 58.2 0.6 2.2 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 AMK75700.1 - 9.3e-08 32.1 0.2 9.3e-08 32.1 0.2 2.6 2 1 1 3 3 3 1 SurA N-terminal domain Trigger_C PF05698.14 AMK75700.1 - 0.0018 18.3 1.1 0.0018 18.3 1.1 2.5 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus LptD PF04453.14 AMK75701.1 - 6.4e-94 315.3 11.4 9.3e-94 314.8 11.4 1.2 1 0 0 1 1 1 1 LPS transport system D OstA PF03968.14 AMK75701.1 - 0.00034 20.8 0.0 0.00092 19.4 0.0 1.8 1 0 0 1 1 1 1 OstA-like protein APH PF01636.23 AMK75702.1 - 7.1e-27 94.9 0.3 1.2e-26 94.1 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 AMK75702.1 - 0.00021 20.7 0.0 0.00094 18.6 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 AMK75702.1 - 0.049 12.5 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) NTP_transferase PF00483.23 AMK75703.1 - 4.2e-24 85.5 0.0 1e-22 80.9 0.0 2.0 1 1 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AMK75703.1 - 1.9e-14 54.3 0.0 2.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AMK75703.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4244 PF14029.6 AMK75703.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DUF2249 PF10006.9 AMK75703.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) UPF0093 PF03653.13 AMK75704.1 - 9.6e-51 171.9 8.2 1.1e-50 171.7 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) CopD PF05425.13 AMK75704.1 - 4.4e-06 27.0 1.5 4.4e-06 27.0 1.5 1.6 2 0 0 2 2 2 1 Copper resistance protein D DUF2214 PF09980.9 AMK75704.1 - 0.11 12.3 9.3 0.35 10.7 9.3 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2214) DUF4124 PF13511.6 AMK75705.1 - 3.7e-07 30.4 0.0 3.7e-07 30.4 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4124) EMP24_GP25L PF01105.24 AMK75705.1 - 0.027 14.4 1.8 0.04 13.9 1.8 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2868 PF11067.8 AMK75705.1 - 0.12 11.9 7.9 0.13 11.7 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) UPF0242 PF06785.11 AMK75705.1 - 0.13 12.4 9.3 0.16 12.0 9.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FNIP_N PF14636.6 AMK75705.1 - 0.2 12.7 6.5 0.25 12.3 6.5 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus APG6_N PF17675.1 AMK75705.1 - 0.2 12.2 15.8 0.28 11.7 15.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region PA26 PF04636.13 AMK75705.1 - 0.41 9.5 5.4 0.46 9.3 5.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 AMK75705.1 - 0.93 8.2 8.5 1.1 7.9 8.5 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 AMK75705.1 - 2.6 5.9 9.6 3.1 5.6 9.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rtf2 PF04641.12 AMK75705.1 - 2.6 7.4 11.5 3.1 7.1 11.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DOR PF14839.6 AMK75705.1 - 5.1 7.0 13.9 6.6 6.6 13.9 1.1 1 0 0 1 1 1 0 DOR family MAJIN PF15077.6 AMK75705.1 - 5.8 6.6 6.5 7 6.4 6.5 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein LAB_N PF07578.11 AMK75706.1 - 3.6e-32 110.2 2.2 5e-32 109.8 2.2 1.2 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain Glycos_transf_2 PF00535.26 AMK75707.1 - 1e-25 90.5 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK75707.1 - 9.3e-09 35.5 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK75707.1 - 0.00034 20.2 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK75707.1 - 0.013 15.9 0.3 0.11 13.0 0.3 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 NTP_transf_3 PF12804.7 AMK75707.1 - 0.083 13.2 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Atg29_N PF18388.1 AMK75707.1 - 0.088 12.6 0.3 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 Atg29 N-terminal domain PMT_2 PF13231.6 AMK75708.1 - 1.1e-12 48.4 20.5 1.1e-12 48.4 20.5 3.7 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2583 PF10762.9 AMK75708.1 - 0.86 10.1 7.0 1.4 9.4 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Amidohydro_1 PF01979.20 AMK75709.1 - 3.5e-19 69.3 0.0 4.7e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 AMK75709.1 - 3.9e-07 30.2 0.1 6.1e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Zn-ribbon_8 PF09723.10 AMK75710.1 - 2.8e-16 59.3 0.8 2.8e-16 59.3 0.8 1.9 2 0 0 2 2 2 1 Zinc ribbon domain DUF1178 PF06676.11 AMK75710.1 - 0.0013 19.1 0.4 0.0018 18.7 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1178) HypA PF01155.19 AMK75710.1 - 0.011 15.8 0.2 0.011 15.8 0.2 1.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 AMK75710.1 - 0.05 13.6 1.0 0.05 13.6 1.0 1.8 2 0 0 2 2 2 0 zinc-ribbons Rubredoxin_2 PF18073.1 AMK75710.1 - 0.085 12.6 0.6 0.085 12.6 0.6 2.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 AMK75710.1 - 0.28 10.6 7.3 1.2 8.6 0.1 2.8 3 1 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 AMK75710.1 - 0.31 11.0 4.5 8.5 6.4 0.2 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Ribosomal_L32p PF01783.23 AMK75710.1 - 0.37 11.1 0.0 0.37 11.1 0.0 2.5 2 1 1 3 3 3 0 Ribosomal L32p protein family Zn_Tnp_IS1595 PF12760.7 AMK75710.1 - 0.37 10.8 5.4 6.7 6.8 0.0 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_12 PF11331.8 AMK75710.1 - 0.8 9.6 0.1 0.8 9.6 0.1 2.7 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-NADH-PPase PF09297.11 AMK75710.1 - 6.2 6.6 11.9 1.7 8.4 1.2 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain tRNA-synt_2 PF00152.20 AMK75711.1 - 1.4e-107 359.4 0.0 1.7e-107 359.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 AMK75711.1 - 3.4e-26 91.3 0.0 6.2e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 AMK75711.1 - 2e-17 62.9 0.0 4.1e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AMK75711.1 - 6.6e-05 22.5 0.5 0.47 9.9 0.1 2.8 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 AMK75712.1 - 4.8e-40 137.6 0.0 1.5e-39 135.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) Elong-fact-P_C PF09285.11 AMK75713.1 - 8.2e-27 92.7 0.4 1.6e-26 91.8 0.4 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 AMK75713.1 - 8.9e-27 92.9 0.2 1.7e-26 92.0 0.2 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AMK75713.1 - 1.9e-22 79.0 0.6 4.1e-22 78.0 0.5 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Ubiquitin_3 PF14836.6 AMK75713.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Tcp10_C PF07202.13 AMK75713.1 - 0.06 13.3 0.1 0.085 12.8 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Fer4_14 PF13394.6 AMK75714.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK75714.1 - 3.7e-08 33.7 0.0 6.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 AMK75714.1 - 2.1e-06 28.2 0.0 3.7e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily HTH_DeoR PF08220.12 AMK75714.1 - 0.056 13.2 0.1 1.4 8.7 0.1 3.0 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain PAS_3 PF08447.12 AMK75715.1 - 2.3e-50 168.8 2.3 4.5e-21 74.9 0.2 3.9 4 0 0 4 4 4 3 PAS fold HATPase_c PF02518.26 AMK75715.1 - 1.7e-32 112.3 0.6 3.5e-32 111.2 0.6 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK75715.1 - 4e-29 101.0 0.7 1.1e-28 99.7 0.7 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AMK75715.1 - 1.4e-18 66.6 1.0 4.9e-18 64.9 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AMK75715.1 - 6.6e-17 61.5 1.5 4.3e-05 23.5 0.1 4.5 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 AMK75715.1 - 2.3e-16 59.9 0.1 7.9e-06 26.1 0.0 4.8 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 AMK75715.1 - 4.9e-14 52.5 0.6 3.7e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 PAS fold Hpt PF01627.23 AMK75715.1 - 5.5e-08 33.0 0.4 3.2e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Hpt domain PAS_8 PF13188.7 AMK75715.1 - 0.00015 21.7 0.1 0.02 14.9 0.0 3.5 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 AMK75715.1 - 0.022 14.6 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK75715.1 - 0.03 14.2 0.1 0.087 12.7 0.1 1.8 1 0 0 1 1 1 0 GHKL domain AAA_16 PF13191.6 AMK75715.1 - 0.18 12.2 1.5 0.57 10.5 0.6 2.3 2 0 0 2 2 2 0 AAA ATPase domain GGDEF PF00990.21 AMK75716.1 - 2.1e-51 173.9 0.1 3.1e-51 173.3 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK75716.1 - 7.5e-24 84.1 0.1 1.5e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DsbD_2 PF13386.6 AMK75717.1 - 9.1e-48 162.8 21.1 1.1e-47 162.6 21.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD PF02683.15 AMK75717.1 - 5.3e-05 23.2 3.3 5.3e-05 23.2 3.3 2.1 2 0 0 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF1358 PF07096.11 AMK75717.1 - 0.066 13.2 2.1 0.1 12.6 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) Sigma54_activat PF00158.26 AMK75718.1 - 5e-67 224.8 0.0 7.2e-67 224.3 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK75718.1 - 6.5e-21 74.9 0.0 1.2e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK75718.1 - 2.9e-14 52.5 0.3 5.7e-14 51.6 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK75718.1 - 8e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 AMK75718.1 - 1.8e-06 28.2 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AMK75718.1 - 2.6e-05 24.7 0.0 4.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AMK75718.1 - 8e-05 22.4 0.1 0.00021 21.0 0.1 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Mg_chelatase PF01078.21 AMK75718.1 - 0.00032 20.1 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AMK75718.1 - 0.0042 16.3 0.0 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain MCM PF00493.23 AMK75718.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain HTH_50 PF18024.1 AMK75718.1 - 0.028 14.0 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_lid_7 PF17867.1 AMK75718.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Midasin AAA lid domain IstB_IS21 PF01695.17 AMK75718.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 AMK75718.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Head_binding PF09008.10 AMK75718.1 - 0.21 11.9 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 Head binding PP2C_2 PF13672.6 AMK75719.1 - 1.5e-14 54.1 0.1 3.2e-14 53.1 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AMK75719.1 - 2.5e-07 30.6 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 AMK75719.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PdxJ PF03740.13 AMK75720.1 - 1.6e-103 344.8 3.6 1.9e-103 344.7 3.6 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 AMK75720.1 - 0.024 14.1 1.2 0.061 12.8 1.2 2.1 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_trans_4_4 PF13579.6 AMK75720.1 - 0.046 14.1 1.4 0.099 13.1 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Mpt_N PF09176.11 AMK75720.1 - 0.15 12.2 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal RecO_N PF11967.8 AMK75721.1 - 4.7e-20 71.4 0.0 7.2e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Recombination protein O N terminal RecO_C PF02565.15 AMK75721.1 - 3.8e-15 56.0 2.1 9.8e-14 51.4 2.1 2.1 1 1 0 1 1 1 1 Recombination protein O C terminal MMR_HSR1 PF01926.23 AMK75722.1 - 9.4e-22 77.2 0.0 1.5e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 AMK75722.1 - 4.6e-21 74.4 0.8 1e-20 73.3 0.8 1.6 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 AMK75722.1 - 5.9e-12 45.4 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 AMK75722.1 - 7.7e-09 35.4 0.1 3.6e-07 29.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 AMK75722.1 - 1.5e-08 34.7 0.7 0.00015 21.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AMK75722.1 - 1.3e-06 28.6 0.1 0.00022 21.3 0.1 2.3 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 AMK75722.1 - 4e-06 26.6 0.1 1.7e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 AMK75722.1 - 4.5e-05 22.9 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1_Xtn PF16897.5 AMK75722.1 - 0.00053 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 AMK75722.1 - 0.035 14.3 0.1 0.11 12.8 0.1 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 AMK75722.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 AMK75722.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 AMK75722.1 - 0.076 12.8 0.0 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 AMK75722.1 - 0.096 12.3 0.1 0.6 9.7 0.1 2.1 1 1 0 1 1 1 0 Ras family RNA_helicase PF00910.22 AMK75722.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Cecropin PF00272.19 AMK75722.1 - 0.2 11.4 1.9 0.4 10.4 0.5 2.1 2 0 0 2 2 2 0 Cecropin family DUF5625 PF18539.1 AMK75722.1 - 0.21 11.8 2.1 55 4.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5625) Ribonucleas_3_3 PF14622.6 AMK75723.1 - 1.4e-29 102.8 0.0 2.2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 AMK75723.1 - 2.9e-19 69.6 0.0 5.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 AMK75723.1 - 2e-11 44.4 0.0 3.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 AMK75723.1 - 4.8e-07 29.9 0.2 1.4e-06 28.5 0.2 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF4845 PF16137.5 AMK75724.1 - 4.3e-22 78.8 2.4 5.2e-22 78.5 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4845) SpoVS PF04232.12 AMK75724.1 - 0.014 15.1 0.2 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) Peptidase_S24 PF00717.23 AMK75725.1 - 2e-24 85.3 0.4 4e-24 84.4 0.4 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AMK75725.1 - 4.7e-13 49.1 0.1 2.8e-07 30.4 0.0 2.7 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 GTP_EFTU PF00009.27 AMK75726.1 - 2.6e-52 177.2 0.1 1e-51 175.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AMK75726.1 - 5.9e-51 171.1 4.1 1.1e-50 170.2 4.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AMK75726.1 - 5.3e-22 77.7 0.0 1.6e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AMK75726.1 - 1.5e-09 38.1 3.2 1.6e-09 38.0 1.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 AMK75726.1 - 3.2e-05 23.9 0.0 8.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 AMK75726.1 - 0.00011 21.9 0.0 0.00034 20.2 0.0 1.9 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 AMK75726.1 - 0.00014 21.9 0.0 0.00063 19.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 AMK75726.1 - 0.00053 19.8 0.6 0.0052 16.5 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RF3_C PF16658.5 AMK75726.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 AMK75726.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 AMK75726.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 AMK75726.1 - 0.094 12.6 0.0 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase ZipA_C PF04354.13 AMK75727.1 - 4.7e-35 120.2 0.0 6.7e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain SMC_N PF02463.19 AMK75728.1 - 8.5e-53 179.0 43.3 8.8e-52 175.7 43.3 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK75728.1 - 1.2e-21 78.2 0.4 1.2e-21 78.2 0.4 6.8 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 AMK75728.1 - 1.7e-17 64.2 0.0 1.7e-17 64.2 0.0 3.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 AMK75728.1 - 1.9e-13 50.9 4.8 7.5e-07 29.2 0.0 2.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK75728.1 - 2.2e-06 27.3 0.0 5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 AMK75728.1 - 2.2e-06 28.0 0.0 1.4e-05 25.4 0.0 2.5 1 1 0 1 1 1 1 SMC proteins Flexible Hinge Domain ADIP PF11559.8 AMK75728.1 - 0.0009 19.4 5.3 0.0009 19.4 5.3 10.0 2 2 8 10 10 10 1 Afadin- and alpha -actinin-Binding ABC_tran PF00005.27 AMK75728.1 - 0.0093 16.5 0.0 0.0093 16.5 0.0 7.7 3 2 0 3 3 3 1 ABC transporter Arm-DNA-bind_2 PF12167.8 AMK75728.1 - 0.38 10.7 1.8 2.6 8.0 1.2 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain QueF PF14489.6 AMK75730.1 - 1.7e-31 108.2 0.0 2.1e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 QueF-like protein Bac_export_2 PF01312.19 AMK75731.1 - 1.3e-21 77.2 0.7 1.6e-21 76.9 0.7 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family PS_Dcarbxylase PF02666.15 AMK75732.1 - 2.5e-61 206.8 0.0 3.1e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase YajC PF02699.15 AMK75733.1 - 8.2e-26 89.7 0.1 1.1e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit DUF5391 PF17369.2 AMK75733.1 - 0.096 12.7 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5391) SecD-TM1 PF13721.6 AMK75734.1 - 3.6e-34 117.3 5.4 2.2e-28 98.7 0.1 3.6 4 0 0 4 4 4 2 SecD export protein N-terminal TM region SecD_SecF PF02355.16 AMK75734.1 - 2.7e-19 69.3 10.4 5.5e-19 68.3 10.4 1.4 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 AMK75734.1 - 1.8e-07 30.4 0.0 4.3e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif MMPL PF03176.15 AMK75734.1 - 0.00012 21.1 15.4 0.00012 21.1 15.4 2.0 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.19 AMK75734.1 - 0.00044 18.1 9.6 0.00072 17.4 9.6 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family YlaH PF14036.6 AMK75734.1 - 6.6 7.1 14.2 4.9 7.6 0.2 2.7 3 0 0 3 3 3 0 YlaH-like protein NDK PF00334.19 AMK75735.1 - 3.3e-60 202.0 0.0 3.7e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Radical_SAM PF04055.21 AMK75736.1 - 1.3e-19 71.2 0.0 2.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AMK75736.1 - 0.00015 21.9 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK75736.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Corona_6B_7B PF03262.13 AMK75736.1 - 0.11 11.9 0.2 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 Coronavirus 6B/7B protein TPR_2 PF07719.17 AMK75737.1 - 7.6e-17 60.0 3.7 1.3e-06 28.1 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75737.1 - 1.3e-14 53.3 0.7 9.1e-09 34.8 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 AMK75737.1 - 1.7e-14 54.0 1.2 1.8e-05 25.2 1.0 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 AMK75737.1 - 5.5e-14 51.4 1.7 0.021 15.1 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 AMK75737.1 - 2.9e-13 48.9 3.0 7.1e-06 25.8 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75737.1 - 6.1e-12 45.7 3.8 1.2e-07 31.9 0.1 4.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75737.1 - 2.2e-11 44.2 0.0 0.0028 18.2 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75737.1 - 9.2e-11 41.2 1.0 0.00061 19.4 0.0 4.3 2 1 2 4 4 4 2 TPR repeat TPR_7 PF13176.6 AMK75737.1 - 1.3e-10 40.5 0.3 1.7e-06 27.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75737.1 - 3.4e-10 39.9 1.7 0.082 13.8 0.2 5.9 1 1 5 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 AMK75737.1 - 1.4e-08 34.3 1.0 0.0034 17.2 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 AMK75737.1 - 2.9e-06 27.3 1.3 0.0057 16.8 0.3 3.4 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AMK75737.1 - 1.9e-05 25.0 10.7 0.0016 18.9 0.3 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 AMK75737.1 - 6.3e-05 22.3 0.9 0.027 13.7 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK75737.1 - 0.00012 22.3 1.2 1 9.7 0.4 3.6 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 AMK75737.1 - 0.0056 16.1 0.3 1.8 7.9 0.0 2.6 1 1 1 3 3 3 1 Coatomer epsilon subunit TPR_MalT PF17874.1 AMK75737.1 - 0.013 14.9 0.5 0.08 12.3 0.2 2.1 1 1 1 2 2 2 0 MalT-like TPR region Transcrip_reg PF01709.20 AMK75737.1 - 0.036 13.5 0.1 0.13 11.6 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator RPN7 PF10602.9 AMK75737.1 - 0.075 12.7 1.9 13 5.5 0.2 3.3 1 1 2 3 3 3 0 26S proteasome subunit RPN7 PPR PF01535.20 AMK75737.1 - 0.095 13.0 0.5 12 6.4 0.0 3.2 3 0 0 3 3 2 0 PPR repeat Alkyl_sulf_dimr PF14863.6 AMK75737.1 - 0.32 11.4 3.2 2.7 8.5 0.2 2.5 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation tRNA-synt_His PF13393.6 AMK75738.1 - 1.9e-47 162.1 0.0 2.4e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AMK75738.1 - 3.1e-29 102.2 0.0 4.8e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AMK75738.1 - 9.8e-08 32.0 0.0 2.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 AMK75738.1 - 0.0049 16.0 0.0 0.11 11.6 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) TPR_21 PF09976.9 AMK75739.1 - 8.7e-58 195.2 9.2 1e-57 195.0 9.2 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 AMK75739.1 - 8e-06 26.3 8.5 0.18 12.7 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AMK75739.1 - 1.3e-05 25.1 5.4 0.18 12.1 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AMK75739.1 - 2.9e-05 24.5 15.0 0.00021 21.8 2.1 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75739.1 - 0.00013 22.6 8.2 0.093 13.4 0.1 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 AMK75739.1 - 0.00033 21.1 10.6 1.2 10.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 AMK75739.1 - 0.00045 19.2 0.3 0.063 12.2 0.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 AMK75739.1 - 0.0023 18.4 4.0 8.9 7.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 AMK75739.1 - 0.0046 16.2 4.4 0.0069 15.6 0.2 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75739.1 - 0.0065 16.5 6.4 0.11 12.6 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75739.1 - 0.0097 16.2 6.7 0.76 10.1 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75739.1 - 0.027 14.1 4.1 0.044 13.5 0.0 2.9 4 0 0 4 4 4 0 TPR repeat YfiO PF13525.6 AMK75739.1 - 0.039 13.7 1.1 0.039 13.7 1.1 1.6 2 0 0 2 2 2 0 Outer membrane lipoprotein DUF2681 PF10883.8 AMK75739.1 - 0.044 14.2 0.9 0.044 14.2 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) CRISPR_Cse2 PF09485.10 AMK75739.1 - 0.062 13.8 1.2 0.13 12.7 1.1 1.7 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_18 PF13512.6 AMK75739.1 - 0.071 13.2 0.7 0.21 11.7 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK75739.1 - 0.094 12.9 1.0 0.82 9.9 0.3 2.5 2 1 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AMK75739.1 - 0.31 11.0 3.5 9.8 6.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75739.1 - 1.7 8.6 0.0 1.7 8.6 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PQQ_2 PF13360.6 AMK75740.1 - 7.3e-51 173.0 11.6 3.1e-45 154.6 5.4 2.9 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 AMK75740.1 - 5.9e-22 77.5 15.0 0.00045 20.6 0.0 8.1 8 0 0 8 8 8 7 PQQ-like domain PQQ PF01011.21 AMK75740.1 - 7.1e-12 44.7 9.5 0.015 15.2 0.0 6.9 9 0 0 9 9 9 4 PQQ enzyme repeat MMR_HSR1 PF01926.23 AMK75741.1 - 7.2e-56 187.2 0.2 1.4e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 AMK75741.1 - 1.2e-30 106.1 0.0 2.5e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 AMK75741.1 - 6.1e-26 90.6 0.0 1.5e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 AMK75741.1 - 8e-22 77.7 1.1 3.5e-09 36.5 0.0 5.1 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AMK75741.1 - 9e-14 51.9 0.1 0.0046 17.0 0.0 4.3 3 1 1 4 4 4 4 Dynamin family AIG1 PF04548.16 AMK75741.1 - 4.3e-12 45.8 0.1 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AMK75741.1 - 2.5e-09 37.2 0.0 0.00061 19.7 0.0 4.3 3 1 0 3 3 3 2 RsgA GTPase Ras PF00071.22 AMK75741.1 - 6.3e-08 32.4 0.0 0.0029 17.2 0.0 2.5 2 1 0 2 2 2 2 Ras family cobW PF02492.19 AMK75741.1 - 5.9e-07 29.2 3.4 0.0095 15.5 0.2 4.0 2 2 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 AMK75741.1 - 6.7e-06 26.3 0.0 0.15 12.3 0.0 3.4 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 AMK75741.1 - 7e-06 26.6 0.0 0.078 13.5 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 AMK75741.1 - 2.4e-05 24.8 0.1 0.27 11.6 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 AMK75741.1 - 5.9e-05 23.6 0.0 0.28 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.17 AMK75741.1 - 6.3e-05 22.9 0.0 0.81 9.4 0.0 3.8 3 1 0 4 4 4 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 AMK75741.1 - 8.8e-05 22.8 0.0 0.77 10.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 AMK75741.1 - 0.00012 21.9 0.0 0.068 12.9 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AMK75741.1 - 0.00019 21.7 0.0 0.22 11.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain SRPRB PF09439.10 AMK75741.1 - 0.00021 20.7 0.0 0.08 12.4 0.0 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 AMK75741.1 - 0.00061 19.0 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Arf PF00025.21 AMK75741.1 - 0.00063 19.2 0.1 0.25 10.8 0.0 3.2 2 2 0 2 2 2 1 ADP-ribosylation factor family RNA_helicase PF00910.22 AMK75741.1 - 0.00071 19.9 0.0 2.1 8.8 0.0 2.8 2 1 0 2 2 2 2 RNA helicase MMR_HSR1_Xtn PF16897.5 AMK75741.1 - 0.00085 19.3 0.0 0.054 13.5 0.0 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 AMK75741.1 - 0.0014 18.4 0.0 0.31 10.8 0.0 3.4 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 AMK75741.1 - 0.002 18.1 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 1 NTPase AAA_14 PF13173.6 AMK75741.1 - 0.0025 17.8 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AMK75741.1 - 0.0028 17.1 0.0 0.75 9.2 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein Ploopntkinase3 PF18751.1 AMK75741.1 - 0.0066 16.4 0.0 0.96 9.3 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 AMK75741.1 - 0.0078 16.4 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AMK75741.1 - 0.0087 15.8 0.0 2.7 7.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MeaB PF03308.16 AMK75741.1 - 0.0095 14.9 0.7 2.5 7.0 0.0 3.6 4 0 0 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 AMK75741.1 - 0.025 14.5 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 AMK75741.1 - 0.037 13.3 0.0 3 7.0 0.0 2.8 2 1 0 3 3 3 0 Septin AAA PF00004.29 AMK75741.1 - 0.042 14.3 0.0 13 6.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GBP PF02263.19 AMK75741.1 - 0.085 12.1 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_25 PF13481.6 AMK75741.1 - 0.095 12.3 0.0 24 4.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AnfO_nitrog PF09582.10 AMK75741.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) MobB PF03205.14 AMK75741.1 - 0.12 12.3 0.0 5.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 AMK75741.1 - 0.18 11.6 0.0 70 3.1 0.0 3.6 4 0 0 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NOG1 PF06858.14 AMK75741.1 - 0.28 11.0 2.4 5.8 6.8 1.1 3.0 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Redoxin PF08534.10 AMK75742.1 - 2.2e-28 98.8 0.1 2.6e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AMK75742.1 - 1.2e-17 63.9 0.0 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.12 AMK75742.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Metal_resist PF13801.6 AMK75743.1 - 0.82 9.9 4.2 1 9.5 0.8 2.2 2 1 0 2 2 2 0 Heavy-metal resistance Gly-zipper_OmpA PF13436.6 AMK75744.1 - 7.7e-07 28.8 34.0 1.1e-06 28.3 34.0 1.2 1 0 0 1 1 1 1 Glycine-zipper domain DUF3482 PF11981.8 AMK75744.1 - 0.54 9.6 11.0 0.68 9.3 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) TraT PF05818.12 AMK75744.1 - 0.77 9.4 5.7 0.94 9.1 5.7 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DctM PF06808.12 AMK75744.1 - 1.4 7.6 6.8 2 7.2 6.8 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Gly-zipper_Omp PF13488.6 AMK75744.1 - 3.7 7.6 31.0 5.7 7.0 30.7 1.5 1 1 0 1 1 1 0 Glycine zipper CxxCxxCC PF03692.15 AMK75746.1 - 7.6e-09 36.1 1.0 1.1e-08 35.6 1.0 1.3 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain GST_N_4 PF17172.4 AMK75747.1 - 1.1e-28 99.9 0.0 1.5e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AMK75747.1 - 4.9e-16 59.2 0.0 7.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 AMK75747.1 - 1.3e-13 50.6 0.0 2.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AMK75747.1 - 1.7e-09 37.9 0.0 9.2e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK75747.1 - 8e-06 26.1 0.0 2.8e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK75747.1 - 1.1e-05 25.3 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AMK75747.1 - 4.4e-05 23.8 0.0 0.00029 21.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LysR_substrate PF03466.20 AMK75748.1 - 1.8e-29 102.6 4.2 1.8e-29 102.6 4.2 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AMK75748.1 - 1.5e-14 53.6 0.2 3.6e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family RVP_2 PF08284.11 AMK75748.1 - 0.025 14.3 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease HTH_30 PF13556.6 AMK75748.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mga PF05043.13 AMK75748.1 - 0.083 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Tautomerase_3 PF14832.6 AMK75749.1 - 1.5e-45 154.7 0.1 1.8e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 AMK75749.1 - 0.00029 20.7 0.0 0.00091 19.1 0.0 1.9 1 1 0 1 1 1 1 Tautomerase enzyme Aldedh PF00171.22 AMK75750.1 - 3.2e-128 428.1 0.1 3.6e-128 428.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lectin_N PF03954.14 AMK75751.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain TIP41 PF04176.13 AMK75751.1 - 0.18 11.2 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 TIP41-like family GGDEF PF00990.21 AMK75752.1 - 4.6e-43 146.7 0.0 1e-42 145.7 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AMK75752.1 - 1.4e-18 67.0 0.0 1.4e-14 54.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AMK75752.1 - 2.8e-14 53.1 0.0 1.3e-10 41.3 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AMK75752.1 - 3.1e-12 46.7 0.0 2.9e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AMK75752.1 - 1.9e-11 43.7 0.1 4.4e-09 36.2 0.1 2.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AMK75752.1 - 1.1e-07 32.1 0.2 0.00012 22.3 0.0 3.4 3 1 0 3 3 3 2 PAS fold GGDEF_2 PF17853.1 AMK75752.1 - 0.0069 16.6 0.1 0.023 15.0 0.1 2.0 1 1 0 1 1 1 1 GGDEF-like domain PAS_7 PF12860.7 AMK75752.1 - 0.053 13.7 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 PAS fold RuvA_C PF07499.13 AMK75752.1 - 0.51 10.8 3.0 7.6 7.1 0.2 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain TPR_MLP1_2 PF07926.12 AMK75752.1 - 0.65 10.1 7.2 0.7 10.0 0.2 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3552 PF12072.8 AMK75752.1 - 2 7.8 7.7 1.3 8.4 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Rabaptin PF03528.15 AMK75752.1 - 2.2 6.9 7.6 0.14 10.8 2.5 1.4 2 0 0 2 2 2 0 Rabaptin HTH_Crp_2 PF13545.6 AMK75753.1 - 7.2e-14 51.5 0.7 1.6e-13 50.4 0.7 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AMK75753.1 - 3.5e-06 27.0 0.0 6.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MarR_2 PF12802.7 AMK75753.1 - 3.2e-05 23.7 0.1 0.00011 22.1 0.1 1.9 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AMK75753.1 - 0.0044 16.9 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AMK75753.1 - 0.0054 17.1 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator GntR PF00392.21 AMK75753.1 - 0.0093 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family CxC2 PF18803.1 AMK75753.1 - 0.14 12.3 0.2 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases PAS_4 PF08448.10 AMK75754.1 - 3.3e-48 162.5 0.3 3.4e-19 69.1 0.0 7.4 7 0 0 7 7 7 6 PAS fold PAS_3 PF08447.12 AMK75754.1 - 2.2e-45 152.9 0.2 2.3e-23 82.3 0.1 6.0 6 0 0 6 6 6 4 PAS fold PAS_9 PF13426.7 AMK75754.1 - 4.3e-41 139.4 0.0 6.5e-07 29.6 0.0 7.6 7 0 0 7 7 7 7 PAS domain PAS PF00989.25 AMK75754.1 - 1.3e-38 131.5 0.0 1.8e-09 37.6 0.0 7.5 7 1 0 7 7 7 6 PAS fold PAS_8 PF13188.7 AMK75754.1 - 7.5e-14 51.4 5.9 0.00025 21.0 0.0 6.6 7 0 0 7 7 7 4 PAS domain HATPase_c PF02518.26 AMK75754.1 - 3.7e-12 46.8 0.0 8.9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AMK75754.1 - 6e-12 46.1 0.0 1.1e-07 32.4 0.0 5.2 6 0 0 6 6 6 1 PAS domain PAS_7 PF12860.7 AMK75754.1 - 2.9e-09 37.1 0.0 0.22 11.7 0.0 6.3 5 0 0 5 5 5 2 PAS fold HisKA PF00512.25 AMK75754.1 - 1.3e-07 31.5 6.0 1.6e-07 31.3 0.2 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AMK75754.1 - 0.0079 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 GHKL domain PAS_2 PF08446.11 AMK75754.1 - 0.095 13.4 0.0 3.2 8.5 0.0 3.4 3 0 0 3 3 3 0 PAS fold Response_reg PF00072.24 AMK75755.1 - 3.8e-28 97.9 0.0 7.7e-28 96.9 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AMK75755.1 - 4.7e-19 67.7 0.6 7.4e-19 67.1 0.6 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AMK75755.1 - 6e-06 25.8 0.2 1e-05 25.1 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AMK75755.1 - 7.6e-05 22.4 0.1 0.00016 21.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AMK75755.1 - 0.00015 21.7 0.1 0.00022 21.1 0.1 1.3 1 0 0 1 1 1 1 ECF sigma factor HTH_38 PF13936.6 AMK75755.1 - 0.0057 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AMK75755.1 - 0.0058 16.1 0.5 0.018 14.6 0.5 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 AMK75755.1 - 0.01 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AMK75755.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 AMK75755.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 KORA PF16509.5 AMK75755.1 - 0.12 12.7 0.2 0.19 12.0 0.2 1.3 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Tautomerase_2 PF14552.6 AMK75756.1 - 5.4e-32 109.7 0.3 1.5e-31 108.4 0.1 1.7 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase PF01361.21 AMK75756.1 - 6.9e-12 45.1 0.1 3.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 2 Tautomerase enzyme Ferritin-like PF12902.7 AMK75756.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 Ferritin-like MFS_1 PF07690.16 AMK75757.1 - 2.1e-47 161.7 50.4 4.3e-36 124.6 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AMK75757.1 - 0.0013 17.7 33.2 0.042 12.7 11.9 2.9 2 2 0 2 2 2 2 Sugar (and other) transporter AmoC PF04896.12 AMK75758.1 - 5.7e-95 317.3 12.7 6.8e-95 317.0 12.7 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C Cation_ATPase_C PF00689.21 AMK75758.1 - 0.02 14.6 0.7 0.041 13.6 0.1 1.7 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2523 PF10734.9 AMK75758.1 - 0.093 13.3 1.8 0.18 12.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) ESSS PF10183.9 AMK75758.1 - 1.6 9.0 6.7 3.9 7.7 0.1 2.9 1 1 2 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Monooxygenase_B PF04744.12 AMK75759.1 - 8e-152 505.5 0.0 9e-152 505.3 0.0 1.0 1 0 0 1 1 1 1 Monooxygenase subunit B protein AMO PF02461.16 AMK75760.1 - 2.4e-112 374.5 15.2 2.9e-112 374.2 15.2 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase LysR_substrate PF03466.20 AMK75761.1 - 4.7e-20 71.8 1.9 7.2e-20 71.3 1.9 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK75761.1 - 2.5e-13 49.7 0.5 7.7e-13 48.2 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MRJP PF03022.16 AMK75762.1 - 3.4e-15 56.2 0.0 3.9e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 AMK75762.1 - 0.018 14.6 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 AMK75762.1 - 0.018 15.2 1.5 8.8 6.9 0.1 3.4 3 1 0 3 3 3 0 Two component regulator propeller DUF5504 PF17608.2 AMK75762.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5504) NHL PF01436.21 AMK75762.1 - 4.3 7.6 6.8 1.6 8.9 0.3 3.3 4 0 0 4 4 4 0 NHL repeat EAL PF00563.20 AMK75763.1 - 5.9e-72 242.0 0.0 1.1e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK75763.1 - 1.8e-51 174.1 0.4 3.6e-51 173.1 0.4 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK75763.1 - 2.9e-38 130.3 0.0 7.7e-13 48.6 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AMK75763.1 - 2.4e-32 111.3 0.0 5.6e-14 52.1 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 AMK75763.1 - 9.5e-26 89.9 0.0 4.1e-11 43.0 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AMK75763.1 - 2.5e-25 88.0 1.3 3.9e-07 29.9 0.0 4.6 6 0 0 6 6 6 3 PAS domain PAS_4 PF08448.10 AMK75763.1 - 2e-19 69.9 0.0 3.2e-08 33.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_7 PF12860.7 AMK75763.1 - 9.9e-05 22.5 0.0 5.7 7.1 0.0 4.7 4 2 0 4 4 4 2 PAS fold PAS_12 PF18095.1 AMK75763.1 - 0.018 14.7 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain DUF1774 PF08611.10 AMK75763.1 - 9.3 6.6 8.6 75 3.7 1.8 3.5 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) Response_reg PF00072.24 AMK75764.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.6 2 0 0 2 2 2 0 Response regulator receiver domain TagA PF12561.8 AMK75765.1 - 0.1 13.0 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain SNase PF00565.17 AMK75767.1 - 4.1e-25 88.4 0.2 6.5e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF4124 PF13511.6 AMK75767.1 - 1e-08 35.4 0.1 2.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) Retrotran_gag_3 PF14244.6 AMK75767.1 - 0.045 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1415 PF07209.12 AMK75768.1 - 5.6e-68 228.0 0.0 6.4e-68 227.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) HTH_Tnp_1 PF01527.20 AMK75769.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK75769.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK75769.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75769.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK75769.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK75769.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK75770.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK75770.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK75770.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK75770.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK75770.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK75770.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK75770.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 Hemerythrin PF01814.23 AMK75771.1 - 2.2e-08 34.8 0.9 3e-08 34.3 0.9 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TOM20_plant PF06552.12 AMK75772.1 - 2.5e-05 24.1 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_8 PF13181.6 AMK75772.1 - 0.00073 19.6 1.8 8.2 6.9 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 AMK75772.1 - 0.0016 19.0 0.8 3.7 8.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75772.1 - 0.015 15.1 6.5 0.7 9.8 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75772.1 - 0.018 15.3 8.0 1.5 9.2 0.7 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75772.1 - 0.038 14.8 2.8 3.1 8.9 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 AMK75772.1 - 0.057 14.1 1.7 0.2 12.4 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CODH_A_N PF18537.1 AMK75772.1 - 0.074 13.1 0.0 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain TPR_2 PF07719.17 AMK75772.1 - 0.13 12.4 7.2 0.75 10.1 0.5 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK75772.1 - 0.24 11.3 4.8 2.1 8.3 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2288 PF10052.9 AMK75773.1 - 1.8e-30 104.9 2.4 2.1e-30 104.7 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2288) Pro-kuma_activ PF09286.11 AMK75773.1 - 0.15 12.3 0.2 0.22 11.8 0.2 1.2 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain DoxX PF07681.12 AMK75774.1 - 2.3e-19 69.7 9.4 2.3e-19 69.7 9.4 1.9 2 0 0 2 2 2 1 DoxX DoxX_2 PF13564.6 AMK75774.1 - 1.1e-05 25.4 8.6 1.1e-05 25.4 8.6 2.0 2 0 0 2 2 2 1 DoxX-like family SURF4 PF02077.15 AMK75774.1 - 0.0083 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 SURF4 family DoxD PF04173.13 AMK75774.1 - 0.042 13.8 7.1 2 8.3 2.2 2.9 2 1 0 3 3 3 0 TQO small subunit DoxD Cupin_2 PF07883.11 AMK75775.1 - 5.8e-10 38.7 0.0 7.1e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 AMK75775.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 AMK75775.1 - 0.00073 19.5 0.0 0.00093 19.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 AMK75775.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 AMK75775.1 - 0.031 14.0 0.1 0.055 13.2 0.1 1.4 1 1 0 1 1 1 0 Cupin-like domain DEAD PF00270.29 AMK75776.1 - 1.1e-49 168.6 0.0 2e-49 167.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK75776.1 - 5.5e-28 97.5 0.0 1.3e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AMK75776.1 - 7.8e-07 29.2 0.0 1.8e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AMK75776.1 - 0.0051 17.1 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AMK75776.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 AMK75776.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 AMK75776.1 - 0.021 15.1 1.0 0.12 12.6 1.0 2.2 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 AMK75776.1 - 0.022 13.5 0.0 7.7 5.2 0.0 3.6 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PilZ PF07238.14 AMK75777.1 - 0.0021 18.3 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 PilZ domain RapA_C PF12137.8 AMK75778.1 - 6.7e-131 436.6 3.8 6.7e-131 436.6 3.8 2.0 2 0 0 2 2 2 1 RNA polymerase recycling family C-terminal Tudor_1_RapA PF18339.1 AMK75778.1 - 9.3e-24 83.1 0.1 5e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 RapA N-terminal Tudor like domain 1 Tudor_RapA PF18337.1 AMK75778.1 - 3.3e-23 81.6 0.7 3.3e-23 81.6 0.7 2.2 2 0 0 2 2 2 1 RapA N-terminal Tudor like domain SNF2_N PF00176.23 AMK75778.1 - 9.9e-14 50.8 0.0 4e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AMK75778.1 - 1.6e-13 50.9 2.5 4.5e-13 49.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AMK75778.1 - 1.4e-10 41.4 0.0 5.6e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AMK75778.1 - 0.00089 19.1 0.0 0.011 15.5 0.0 2.9 3 2 1 4 4 4 1 DEAD/DEAH box helicase RTC PF01137.21 AMK75778.1 - 0.081 12.1 0.4 3.3 6.8 0.1 2.2 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase DUF1323 PF07037.11 AMK75778.1 - 5.8 7.3 9.0 9 6.7 0.0 3.8 4 0 0 4 4 4 0 Putative transcription regulator (DUF1323) NUDIX PF00293.28 AMK75779.1 - 1.8e-18 66.8 0.0 2.1e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain DapB_C PF05173.14 AMK75780.1 - 1.9e-43 147.3 0.2 2.6e-43 146.9 0.2 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 AMK75780.1 - 6e-39 133.0 2.0 8.9e-39 132.4 0.3 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 AMK75780.1 - 4.1e-07 30.0 1.3 7.2e-07 29.2 1.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 AMK75780.1 - 0.00011 22.6 0.2 0.00025 21.5 0.2 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AMK75780.1 - 0.0019 18.5 1.0 0.0054 17.0 0.6 1.9 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AMK75780.1 - 0.0025 17.7 1.1 0.0052 16.7 1.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding CoA_binding_2 PF13380.6 AMK75780.1 - 0.012 16.1 0.9 0.048 14.1 0.9 2.0 1 1 0 1 1 1 0 CoA binding domain DnaJ_C PF01556.18 AMK75781.1 - 1.8e-43 148.2 0.0 2.4e-43 147.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AMK75781.1 - 9.2e-27 93.0 4.8 1.4e-26 92.4 4.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AMK75781.1 - 2.3e-14 53.5 19.6 4.1e-14 52.7 19.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AMK75781.1 - 0.00035 20.5 20.5 0.018 15.0 4.6 2.8 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 AMK75781.1 - 0.045 13.8 9.3 0.19 11.8 0.8 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 AMK75781.1 - 0.23 11.6 0.3 0.23 11.6 0.3 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 AMK75781.1 - 7.1 6.2 7.7 0.5 10.0 0.9 2.0 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HSP70 PF00012.20 AMK75782.1 - 4e-261 867.5 10.7 4.6e-261 867.3 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AMK75782.1 - 1.9e-12 46.7 0.6 3.7e-09 35.8 0.1 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 AMK75782.1 - 0.00037 20.9 4.1 0.58 10.6 0.1 3.8 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 AMK75782.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1090 PF06476.12 AMK75782.1 - 0.081 13.1 7.0 0.21 11.7 7.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) GrpE PF01025.19 AMK75783.1 - 6.4e-49 165.8 0.8 8.4e-49 165.4 0.8 1.1 1 0 0 1 1 1 1 GrpE KxDL PF10241.9 AMK75783.1 - 0.024 14.9 1.2 0.057 13.7 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein SurA_N_2 PF13623.6 AMK75783.1 - 0.029 14.3 1.4 0.29 11.0 1.2 2.1 2 0 0 2 2 2 0 SurA N-terminal domain Apt1 PF10351.9 AMK75783.1 - 0.056 12.3 0.9 0.071 12.0 0.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4390 PF14334.6 AMK75783.1 - 0.11 11.9 0.3 0.18 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) TnpV PF14198.6 AMK75783.1 - 0.12 12.4 1.0 0.24 11.4 1.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Adaptin_binding PF10199.9 AMK75783.1 - 0.9 10.2 8.3 1.9 9.1 8.3 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 HrcA PF01628.21 AMK75784.1 - 1.4e-61 208.2 0.8 1.9e-61 207.8 0.8 1.2 1 0 0 1 1 1 1 HrcA protein C terminal domain HrcA_DNA-bdg PF03444.15 AMK75784.1 - 4.3e-05 23.1 0.0 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Rick_17kDa_Anti PF05433.15 AMK75785.1 - 1.8e-05 24.5 25.0 0.00021 21.1 16.7 1.8 1 1 1 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 AMK75785.1 - 3.9e-05 23.3 9.8 6.7e-05 22.6 9.8 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AMK75785.1 - 0.0074 16.3 16.7 0.026 14.5 16.8 1.8 1 1 0 1 1 1 1 Glycine zipper Bacteriocin_IIc PF10439.9 AMK75785.1 - 0.087 13.0 4.2 0.12 12.5 4.2 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF2076 PF09849.9 AMK75785.1 - 0.23 11.5 0.0 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_OmpA PF13436.6 AMK75785.1 - 3.6 7.5 21.8 0.29 10.9 9.4 2.2 1 1 1 2 2 2 0 Glycine-zipper domain HupE_UreJ_2 PF13795.6 AMK75786.1 - 4.7e-47 159.5 6.5 6.4e-47 159.1 6.5 1.2 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ PF04955.12 AMK75786.1 - 1.5e-07 31.0 6.7 2.4e-07 30.4 6.7 1.3 1 0 0 1 1 1 1 HupE / UreJ protein COLFI PF01410.18 AMK75786.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Plug PF07715.15 AMK75787.1 - 6.9e-14 52.3 0.2 2.5e-13 50.5 0.2 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain HupE_UreJ PF04955.12 AMK75788.1 - 5e-43 146.7 17.7 8.5e-43 145.9 17.7 1.3 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ_2 PF13795.6 AMK75788.1 - 0.0073 16.0 10.7 0.013 15.2 10.7 1.3 1 0 0 1 1 1 1 HupE / UreJ protein DUF3488 PF11992.8 AMK75788.1 - 6.1 5.7 11.6 11 4.9 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) F_bP_aldolase PF01116.20 AMK75789.1 - 1e-89 300.8 0.1 1.2e-89 300.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AP_endonuc_2 PF01261.24 AMK75789.1 - 0.091 12.2 0.0 0.82 9.1 0.0 2.5 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Collar PF07484.12 AMK75789.1 - 0.23 11.5 0.2 61 3.7 0.0 3.5 3 1 1 4 4 4 0 Phage Tail Collar Domain Sigma54_activat PF00158.26 AMK75790.1 - 1.5e-53 180.9 0.0 2.3e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK75790.1 - 1.8e-25 89.3 0.1 3e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AMK75790.1 - 2.6e-21 76.2 0.0 6.7e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK75790.1 - 1.7e-08 34.1 6.0 2.1e-08 33.8 1.9 2.9 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family FleQ PF06490.11 AMK75790.1 - 0.0004 20.7 0.1 0.001 19.4 0.1 1.8 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ AAA_5 PF07728.14 AMK75790.1 - 0.00049 20.1 0.0 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TadZ_N PF16968.5 AMK75790.1 - 0.001 18.8 0.5 0.0025 17.5 0.5 1.6 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal Mg_chelatase PF01078.21 AMK75790.1 - 0.015 14.7 0.2 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 AMK75790.1 - 0.039 14.4 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK75790.1 - 0.1 13.0 3.1 0.12 12.8 0.1 2.7 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 AMK75790.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HATPase_c PF02518.26 AMK75791.1 - 5.6e-20 71.9 0.0 1.1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AMK75791.1 - 8e-11 41.9 0.0 3.1e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AMK75791.1 - 6.3e-09 36.0 0.0 2.3e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AMK75791.1 - 6.7e-09 35.6 0.0 3.3e-08 33.4 0.0 2.3 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 AMK75791.1 - 1.4e-06 28.3 4.7 1.4e-06 28.2 0.0 3.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AMK75791.1 - 3.1e-05 24.2 0.0 0.00024 21.3 0.0 2.6 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AMK75791.1 - 0.0012 18.8 0.2 0.012 15.6 0.2 2.3 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AMK75791.1 - 0.0028 17.5 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain PAS_7 PF12860.7 AMK75791.1 - 0.07 13.3 0.0 0.3 11.2 0.0 2.2 1 0 0 1 1 1 0 PAS fold JAKMIP_CC3 PF16034.5 AMK75791.1 - 0.86 9.5 6.1 0.71 9.8 0.3 3.1 3 0 0 3 3 3 0 JAKMIP CC3 domain CCP_MauG PF03150.14 AMK75792.1 - 2.4e-43 148.4 0.0 6.8e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 AMK75792.1 - 1.4e-10 42.2 0.0 3.7e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c DHOR PF06537.11 AMK75792.1 - 7.6e-06 24.8 0.0 0.075 11.6 0.0 3.0 3 0 0 3 3 3 2 Di-haem oxidoreductase, putative peroxidase Cytochrome_CBB3 PF13442.6 AMK75792.1 - 3.5e-05 24.0 0.2 0.12 12.7 0.2 2.9 2 1 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 AMK75792.1 - 0.026 14.5 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c PSCyt3 PF07627.11 AMK75792.1 - 0.027 14.8 0.1 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) DUF1924 PF09086.11 AMK75792.1 - 0.066 13.6 0.0 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Methyltranf_PUA PF13636.6 AMK75792.1 - 0.073 13.1 0.1 0.24 11.4 0.1 1.9 1 1 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF PEP-CTERM PF07589.11 AMK75793.1 - 0.079 13.1 1.8 0.19 11.9 1.8 1.7 1 0 0 1 1 1 0 PEP-CTERM motif Bacteriocin_IIc PF10439.9 AMK75794.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Arm-DNA-bind_3 PF13356.6 AMK75796.1 - 7.8e-16 58.2 0.5 1.5e-15 57.3 0.1 1.6 1 1 1 2 2 2 1 Arm DNA-binding domain Arm-DNA-bind_2 PF12167.8 AMK75796.1 - 0.0032 17.4 0.4 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 Arm DNA-binding domain DUF2016 PF09436.10 AMK75796.1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) SecG PF03840.14 AMK75797.1 - 3.9e-20 71.7 12.1 4.8e-20 71.4 12.1 1.1 1 0 0 1 1 1 1 Preprotein translocase SecG subunit TIM PF00121.18 AMK75798.1 - 3.9e-90 301.5 0.0 4.3e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PGM_PMM_I PF02878.16 AMK75799.1 - 5.4e-43 146.0 0.0 9.7e-43 145.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AMK75799.1 - 1.3e-30 106.0 0.7 2.2e-30 105.2 0.1 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AMK75799.1 - 2.4e-18 66.6 0.1 4.7e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AMK75799.1 - 1.9e-15 56.8 1.9 5.7e-15 55.2 1.9 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Peptidase_M41 PF01434.18 AMK75800.1 - 5.2e-73 245.0 0.4 8.2e-73 244.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AMK75800.1 - 3.4e-45 153.7 0.0 7.5e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AMK75800.1 - 1.8e-12 46.8 0.0 3.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 AMK75800.1 - 3.9e-11 43.3 0.3 8.4e-11 42.2 0.0 1.7 2 0 0 2 2 1 1 FtsH Extracellular AAA_5 PF07728.14 AMK75800.1 - 3.4e-05 23.9 0.2 0.00027 21.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AMK75800.1 - 4.3e-05 22.9 0.0 9.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 AMK75800.1 - 0.00054 19.7 0.0 0.0042 16.9 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 AMK75800.1 - 0.001 19.2 0.3 0.04 14.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AMK75800.1 - 0.0011 19.4 0.3 0.074 13.4 0.1 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AMK75800.1 - 0.0012 19.1 0.4 0.22 11.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 AMK75800.1 - 0.0041 16.9 0.1 0.034 13.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 AMK75800.1 - 0.0048 17.1 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain CSTF2_hinge PF14327.6 AMK75800.1 - 0.0094 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Mg_chelatase PF01078.21 AMK75800.1 - 0.016 14.6 0.2 0.034 13.5 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AMK75800.1 - 0.055 13.7 0.2 0.71 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AMK75800.1 - 0.084 13.4 0.4 0.66 10.5 0.1 2.4 2 0 0 2 2 2 0 ABC transporter PanZ PF12568.8 AMK75800.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ ACP_syn_III PF08545.10 AMK75800.1 - 0.12 12.2 0.1 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RNA_helicase PF00910.22 AMK75800.1 - 0.15 12.4 0.1 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 RNA helicase FtsJ PF01728.19 AMK75801.1 - 2e-55 187.6 0.0 2.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 AMK75801.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 AMK75801.1 - 0.03 13.4 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin CRS1_YhbY PF01985.21 AMK75802.1 - 1.5e-22 79.6 0.6 1.6e-22 79.5 0.6 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain GreA_GreB PF01272.19 AMK75803.1 - 5.8e-31 106.2 1.7 9.8e-31 105.5 1.7 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 AMK75803.1 - 2.5e-30 104.4 0.7 4e-30 103.8 0.7 1.3 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal DUF1843 PF08898.10 AMK75803.1 - 0.042 14.4 0.5 0.19 12.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CPSase_L_D2 PF02786.17 AMK75804.1 - 1.1e-110 368.1 0.0 1.6e-72 243.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AMK75804.1 - 2.4e-40 137.7 0.0 6.4e-40 136.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AMK75804.1 - 1.5e-19 70.0 0.2 5.8e-19 68.1 0.2 2.1 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 AMK75804.1 - 3.2e-13 49.6 0.0 1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AMK75804.1 - 3.1e-12 46.4 0.0 2.7e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 AMK75804.1 - 5.8e-11 42.2 0.1 1.1e-06 28.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 AMK75804.1 - 2.4e-09 37.4 0.0 1.1e-05 25.5 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_4 PF13535.6 AMK75804.1 - 1e-06 28.5 0.0 0.002 17.7 0.0 4.1 4 1 0 4 4 4 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AMK75804.1 - 0.00017 21.1 0.0 0.66 9.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Epimerase PF01370.21 AMK75804.1 - 0.0038 16.7 0.0 0.051 13.0 0.0 2.6 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 AMK75804.1 - 0.0044 17.1 0.0 4.8 7.2 0.0 3.6 3 0 0 3 3 3 1 B12 binding domain ComX PF05952.12 AMK75804.1 - 0.0054 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Bacillus competence pheromone ComX ATP-grasp_2 PF08442.10 AMK75804.1 - 0.0065 16.0 0.0 0.77 9.3 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain Peripla_BP_4 PF13407.6 AMK75804.1 - 0.077 12.5 0.1 1.5 8.3 0.0 2.9 3 0 0 3 3 3 0 Periplasmic binding protein domain Isochorismatase PF00857.20 AMK75804.1 - 0.1 12.8 0.3 1.4 9.0 0.1 2.7 3 0 0 3 3 3 0 Isochorismatase family CoA_binding_2 PF13380.6 AMK75804.1 - 0.11 12.9 0.0 5.7 7.5 0.0 3.2 2 1 0 2 2 2 0 CoA binding domain CPSase_sm_chain PF00988.22 AMK75805.1 - 7.4e-50 168.1 0.0 1.5e-49 167.1 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AMK75805.1 - 5.8e-47 159.9 0.0 8.2e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AMK75805.1 - 1.8e-06 27.9 0.1 6.4e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AMK75805.1 - 0.0029 17.4 0.0 0.0075 16.1 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family LTXXQ PF07813.12 AMK75806.1 - 6e-09 36.6 2.3 8.3e-09 36.1 2.3 1.1 1 0 0 1 1 1 1 LTXXQ motif family protein Metal_resist PF13801.6 AMK75806.1 - 5.7e-08 33.0 4.9 2.1e-07 31.2 4.5 2.0 1 1 1 2 2 2 1 Heavy-metal resistance Siah-Interact_N PF09032.11 AMK75806.1 - 0.15 12.4 2.4 0.35 11.2 2.4 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal Response_reg PF00072.24 AMK75807.1 - 1.8e-24 86.1 0.0 3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK75807.1 - 1.6e-22 79.4 0.6 2.5e-22 78.8 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Dimerisation PF08100.11 AMK75807.1 - 0.051 13.6 0.0 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain HATPase_c PF02518.26 AMK75808.1 - 4.9e-18 65.7 0.0 7.6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK75808.1 - 6.7e-15 54.9 1.5 1.9e-14 53.4 1.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK75808.1 - 3.1e-10 40.3 0.1 1.5e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 HAMP domain AbfS_sensor PF18225.1 AMK75808.1 - 7.5e-05 22.6 0.8 0.00026 20.8 0.0 2.1 2 0 0 2 2 2 1 Sensor histidine kinase (AbfS) sensor domain HATPase_c_2 PF13581.6 AMK75808.1 - 0.0002 21.3 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK75808.1 - 0.0081 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK75808.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Gly-zipper_OmpA PF13436.6 AMK75810.1 - 2.2e-06 27.3 35.7 5.1e-06 26.2 35.7 1.7 1 0 0 1 1 1 1 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 AMK75810.1 - 0.00052 19.7 34.8 0.0011 18.7 34.8 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Shadoo PF14999.6 AMK75810.1 - 0.19 11.9 18.3 0.49 10.5 2.4 2.3 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective Autotransporter PF03797.19 AMK75811.1 - 7.5e-46 156.8 23.6 7.5e-46 156.8 23.6 2.4 3 0 0 3 3 3 1 Autotransporter beta-domain Cytochrome_CBB3 PF13442.6 AMK75812.1 - 4.5e-19 68.5 0.9 8.1e-09 35.7 0.2 2.2 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK75812.1 - 7e-13 49.5 5.0 4.2e-07 31.0 0.9 3.2 2 2 0 2 2 2 2 Cytochrome c Paired_CXXCH_1 PF09699.10 AMK75812.1 - 0.00024 20.8 2.0 0.067 13.0 0.4 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) 4HFCP_synth PF04476.13 AMK75812.1 - 0.004 16.9 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 2 4-HFC-P synthase DUF2059 PF09832.9 AMK75812.1 - 0.0092 16.0 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2059) Cytochrome_C7 PF14522.6 AMK75812.1 - 0.02 14.9 0.1 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF1924 PF09086.11 AMK75812.1 - 0.033 14.5 0.9 7.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrom_c3_2 PF14537.6 AMK75812.1 - 0.074 13.5 0.2 19 5.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.16 AMK75812.1 - 0.092 13.1 0.2 7.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Class III cytochrome C family Asp-Al_Ex PF06826.12 AMK75813.1 - 3.9e-81 270.8 41.0 6.9e-43 146.4 12.9 2.1 2 0 0 2 2 2 2 Predicted Permease Membrane Region TrkA_C PF02080.21 AMK75813.1 - 4.1e-12 45.8 0.2 5.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 TrkA-C domain 2OG-FeII_Oxy_2 PF13532.6 AMK75814.1 - 2.7e-32 112.6 0.1 3.1e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sulfatase PF00884.23 AMK75815.1 - 1.7e-26 93.4 0.4 2.6e-26 92.8 0.4 1.3 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 AMK75815.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Rhabdo_glycop PF00974.18 AMK75815.1 - 0.12 10.9 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Got1 PF04178.12 AMK75816.1 - 1.5 9.3 9.9 1.3 9.4 1.5 2.2 2 0 0 2 2 2 0 Got1/Sft2-like family DUF485 PF04341.12 AMK75816.1 - 4.2 7.4 10.5 0.19 11.7 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF485 PGG PF13962.6 AMK75816.1 - 8.7 6.2 9.8 1.6 8.5 2.4 2.5 1 1 2 3 3 3 0 Domain of unknown function LPAM_1 PF08139.12 AMK75817.1 - 0.0069 16.8 3.8 0.025 15.1 3.8 2.0 1 1 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site DUF302 PF03625.14 AMK75818.1 - 9.3e-12 44.7 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 NTP_transf_3 PF12804.7 AMK75819.1 - 4.1e-32 111.8 0.7 4.8e-32 111.5 0.7 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 AMK75819.1 - 0.0032 17.3 0.1 0.0055 16.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) CofC PF01983.16 AMK75819.1 - 0.011 14.9 0.0 0.092 11.9 0.0 1.9 1 1 0 2 2 2 0 Guanylyl transferase CofC like NlpE PF04170.12 AMK75821.1 - 1.2e-23 83.9 0.1 1.6e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 NlpE N-terminal domain PKD PF00801.20 AMK75822.1 - 1.5e-12 47.2 4.6 1.5e-12 47.2 4.6 3.8 3 1 0 3 3 3 1 PKD domain Reprolysin_3 PF13582.6 AMK75822.1 - 4e-08 33.8 0.1 1.8e-07 31.7 0.1 2.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AMK75822.1 - 2.9e-07 30.8 0.3 1.1e-06 28.9 0.3 2.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 AMK75822.1 - 5.2e-06 26.5 0.3 1.2e-05 25.3 0.3 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 AMK75822.1 - 0.00011 21.9 0.3 0.00011 21.9 0.3 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like PPC PF04151.15 AMK75822.1 - 0.00067 20.7 0.9 0.00067 20.7 0.9 4.6 4 0 0 4 4 3 1 Bacterial pre-peptidase C-terminal domain Peptidase_M66 PF10462.9 AMK75822.1 - 0.0021 17.0 0.4 0.0044 16.0 0.4 1.6 1 0 0 1 1 1 1 Peptidase M66 Big_1 PF02369.16 AMK75822.1 - 0.0022 17.9 9.1 0.0022 17.9 9.1 4.8 4 1 0 4 4 4 1 Bacterial Ig-like domain (group 1) CT_C_D PF02682.16 AMK75822.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D DUF4953 PF16313.5 AMK75822.1 - 0.058 12.6 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 AMK75822.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Matrixin M60-like_N PF17291.2 AMK75822.1 - 0.067 13.1 3.2 2 8.3 0.1 3.4 2 1 1 3 3 3 0 N-terminal domain of M60-like peptidases Glyco_hydro2_C5 PF18565.1 AMK75822.1 - 0.16 11.8 4.8 0.53 10.1 1.0 3.1 3 0 0 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 MG4 PF17789.1 AMK75822.1 - 0.79 9.9 4.2 0.54 10.5 0.3 2.8 3 0 0 3 3 3 0 Macroglobulin domain MG4 EcsB PF05975.12 AMK75823.1 - 0.006 15.5 1.8 0.0065 15.4 1.8 1.0 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB COX2 PF00116.20 AMK75824.1 - 8.9e-09 35.3 0.1 1.3e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cupredoxin_1 PF13473.6 AMK75824.1 - 0.00062 19.8 0.0 0.00086 19.4 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain COX1 PF00115.20 AMK75825.1 - 2.3e-88 296.9 73.5 2.3e-88 296.9 73.5 1.7 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrome_CBB3 PF13442.6 AMK75826.1 - 7.8e-13 48.5 0.1 6e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK75826.1 - 3.8e-12 47.2 0.6 1.3e-05 26.3 0.4 3.0 2 1 0 2 2 2 2 Cytochrome c Cytochrome_C7 PF14522.6 AMK75826.1 - 0.0071 16.3 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrome_CBB3 PF13442.6 AMK75827.1 - 0.04 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III HDOD PF08668.12 AMK75828.1 - 5.5e-45 153.3 0.0 7e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK75828.1 - 0.00024 21.3 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 HD domain Sigma54_activat PF00158.26 AMK75829.1 - 4.1e-64 215.3 0.2 6.1e-64 214.8 0.2 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK75829.1 - 1.4e-23 83.5 0.0 3.6e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK75829.1 - 5.1e-06 26.2 0.2 1.1e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA PF00004.29 AMK75829.1 - 1.2e-05 25.7 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PAS_4 PF08448.10 AMK75829.1 - 3.6e-05 24.0 0.3 0.0053 17.0 0.0 3.0 2 1 1 3 3 3 1 PAS fold Mg_chelatase PF01078.21 AMK75829.1 - 0.00074 19.0 0.1 0.087 12.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AMK75829.1 - 0.00093 19.2 0.0 0.0023 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PAS_8 PF13188.7 AMK75829.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK75829.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold AAA_2 PF07724.14 AMK75829.1 - 0.013 15.7 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_28 PF13518.6 AMK75829.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 AMK75829.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_50 PF18024.1 AMK75829.1 - 0.028 14.0 0.1 0.06 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PAS_9 PF13426.7 AMK75829.1 - 0.037 14.3 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 PAS domain AAA_7 PF12775.7 AMK75829.1 - 0.049 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_Tnp_ISL3 PF13542.6 AMK75829.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MLTR_LBD PF17765.1 AMK75829.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain HTH_11 PF08279.12 AMK75829.1 - 0.16 11.9 0.7 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 HTH domain PEP-CTERM PF07589.11 AMK75830.1 - 0.00013 21.9 0.7 0.00027 20.9 0.7 1.5 1 0 0 1 1 1 1 PEP-CTERM motif Ferritin PF00210.24 AMK75831.1 - 1.5e-40 138.4 7.0 1.7e-40 138.3 7.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain FliT PF05400.13 AMK75831.1 - 0.041 14.7 2.4 0.22 12.4 0.2 2.4 1 1 1 2 2 2 0 Flagellar protein FliT Ferritin_2 PF13668.6 AMK75831.1 - 0.059 13.6 2.3 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Ferritin-like domain Rubrerythrin PF02915.17 AMK75831.1 - 0.19 12.2 7.3 0.94 9.9 7.3 1.9 1 1 1 2 2 2 0 Rubrerythrin Fer2_BFD PF04324.15 AMK75832.1 - 7.5e-10 39.0 3.8 1.1e-09 38.5 3.8 1.3 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Ub-RnfH PF03658.14 AMK75833.1 - 4.5e-34 116.7 0.1 5.4e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin Ub-Mut7C PF14451.6 AMK75833.1 - 0.00034 20.4 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Mut7-C ubiquitin ThiS PF02597.20 AMK75833.1 - 0.014 16.0 0.1 0.028 15.0 0.1 1.5 1 1 0 1 1 1 0 ThiS family SLBB PF10531.9 AMK75833.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 SLBB domain Rnf-Nqr PF02508.14 AMK75834.1 - 6.3e-62 208.6 11.7 7.4e-62 208.4 11.7 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein NDUF_B12 PF08122.12 AMK75834.1 - 0.089 12.8 1.2 8.1 6.6 0.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family FMN_bind PF04205.14 AMK75836.1 - 2.3e-18 66.5 0.1 3.6e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 FMN-binding domain SusE PF14292.6 AMK75836.1 - 0.0031 17.7 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 SusE outer membrane protein NQR2_RnfD_RnfE PF03116.15 AMK75837.1 - 4.4e-105 351.3 15.2 5.2e-105 351.0 15.2 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family Complex1_51K PF01512.17 AMK75838.1 - 2.6e-45 154.0 0.0 4.2e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit RnfC_N PF13375.6 AMK75838.1 - 3.1e-32 110.5 0.2 5.7e-32 109.7 0.2 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain SLBB PF10531.9 AMK75838.1 - 4.6e-10 39.2 0.2 1e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 SLBB domain Fer4_7 PF12838.7 AMK75838.1 - 1.2e-09 38.6 5.1 2.5e-09 37.6 5.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK75838.1 - 2.9e-09 36.9 7.3 6.9e-09 35.7 7.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK75838.1 - 1.9e-08 34.3 5.3 5.2e-08 32.9 5.3 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK75838.1 - 5.8e-08 33.1 17.2 2.5e-07 31.0 6.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK75838.1 - 1.2e-07 32.6 3.9 0.011 16.6 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 AMK75838.1 - 6.8e-07 28.8 13.6 0.0019 18.0 2.3 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AMK75838.1 - 3.1e-06 27.6 8.4 2.7e-05 24.6 8.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK75838.1 - 2.2e-05 24.3 16.2 0.011 15.7 2.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AMK75838.1 - 4.8e-05 23.4 7.2 0.00017 21.6 7.2 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK75838.1 - 0.00043 20.2 14.5 0.019 15.0 2.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AMK75838.1 - 0.0005 20.2 9.6 0.026 14.7 0.4 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK75838.1 - 0.00051 20.3 14.1 0.076 13.6 1.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AMK75838.1 - 0.00076 20.2 16.2 0.14 13.2 3.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain NQRA PF05896.11 AMK75838.1 - 0.0011 18.5 0.0 0.0027 17.2 0.0 1.6 1 1 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Fer4_20 PF14691.6 AMK75838.1 - 0.0039 16.9 4.7 0.0081 15.9 4.7 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NQRA_SLBB PF11973.8 AMK75838.1 - 0.047 14.3 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 NQRA C-terminal domain Fer4_22 PF17179.4 AMK75838.1 - 0.15 12.9 10.6 0.71 10.8 3.1 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AMK75838.1 - 9.3 7.1 8.0 26 5.6 1.9 3.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_21 PF14697.6 AMK75839.1 - 5.9e-18 64.8 26.1 7.8e-14 51.6 16.2 2.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain FeS PF04060.13 AMK75839.1 - 1.6e-12 46.8 5.4 1.6e-12 46.8 5.4 2.3 3 0 0 3 3 2 1 Putative Fe-S cluster Fer4 PF00037.27 AMK75839.1 - 3.3e-12 45.7 25.4 3.4e-07 29.8 2.3 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 AMK75839.1 - 6.9e-10 38.9 49.4 5.3e-08 32.9 16.1 2.7 1 1 3 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK75839.1 - 1.9e-09 37.2 17.0 1.2e-06 28.3 2.4 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AMK75839.1 - 1.9e-09 37.9 21.6 4e-05 24.1 3.0 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK75839.1 - 4.3e-09 36.3 30.2 9.2e-08 32.1 15.8 3.0 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK75839.1 - 2.9e-08 34.5 17.5 0.00019 22.3 2.6 3.0 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AMK75839.1 - 5.9e-07 29.2 23.4 3.9e-05 23.5 3.3 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 AMK75839.1 - 0.00013 22.4 17.6 0.021 15.3 3.5 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AMK75839.1 - 0.0014 18.8 15.8 0.11 12.6 2.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 AMK75839.1 - 0.0026 18.6 4.0 0.0026 18.6 4.0 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 AMK75839.1 - 0.003 18.0 20.8 0.033 14.6 3.4 2.6 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AMK75839.1 - 0.0037 18.1 17.3 0.0038 18.0 0.7 2.5 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK75839.1 - 0.0072 16.8 6.7 0.0072 16.8 6.7 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain AFP PF02420.15 AMK75839.1 - 0.031 14.6 11.9 0.44 11.0 1.0 3.0 2 0 0 2 2 2 0 Insect antifreeze protein repeat Fer4_13 PF13370.6 AMK75839.1 - 0.32 11.6 21.3 0.29 11.7 4.3 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AMK75839.1 - 1.3 9.8 17.0 4.4 8.1 4.6 2.9 1 1 2 3 3 2 0 4Fe-4S single cluster domain Rnf-Nqr PF02508.14 AMK75840.1 - 5.5e-59 199.0 21.7 6.1e-59 198.9 21.7 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF4199 PF13858.6 AMK75840.1 - 1.8 9.0 21.4 0.1 13.0 8.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) HATPase_c PF02518.26 AMK75841.1 - 5e-19 68.9 0.0 8.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 AMK75841.1 - 8.5e-18 64.4 0.7 2.6e-15 56.4 0.0 3.4 4 0 0 4 4 4 1 PAS fold PAS_9 PF13426.7 AMK75841.1 - 3.8e-17 62.4 0.0 2e-15 56.9 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 AMK75841.1 - 1.2e-08 35.2 0.1 9.7e-07 29.0 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 AMK75841.1 - 3e-08 33.5 0.0 6.9e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 PAS domain HATPase_c_5 PF14501.6 AMK75841.1 - 3.6e-08 33.2 0.1 8.6e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 GHKL domain PAS_3 PF08447.12 AMK75841.1 - 0.00013 22.2 0.4 0.00037 20.7 0.1 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AMK75841.1 - 0.00024 21.0 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Uds1 PF15456.6 AMK75841.1 - 0.043 14.0 0.4 0.089 13.0 0.4 1.5 1 0 0 1 1 1 0 Up-regulated During Septation PAS_12 PF18095.1 AMK75841.1 - 0.08 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain HisKA PF00512.25 AMK75841.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.6 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Sigma54_activat PF00158.26 AMK75842.1 - 7.7e-70 234.0 0.0 1.3e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK75842.1 - 3.3e-21 75.9 0.0 1.1e-20 74.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain GAF_2 PF13185.6 AMK75842.1 - 1.8e-11 44.5 0.0 2.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain HTH_8 PF02954.19 AMK75842.1 - 2e-11 43.5 0.3 9.9e-11 41.2 0.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family GAF PF01590.26 AMK75842.1 - 7.7e-09 36.3 0.0 1.5e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain AAA PF00004.29 AMK75842.1 - 3.6e-05 24.2 0.0 0.00011 22.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK75842.1 - 3.7e-05 23.7 0.0 0.00013 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AMK75842.1 - 0.00011 21.7 0.0 0.0037 16.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI GAF_3 PF13492.6 AMK75842.1 - 0.00091 19.6 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 GAF domain AAA_2 PF07724.14 AMK75842.1 - 0.0094 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HTH_23 PF13384.6 AMK75842.1 - 0.028 14.2 0.1 0.079 12.8 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain AAA_3 PF07726.11 AMK75842.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FTCD_C PF04961.12 AMK75843.1 - 4.1e-63 212.4 8.3 4.8e-63 212.2 8.3 1.0 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase M PF02370.16 AMK75843.1 - 0.32 11.7 4.2 18 6.3 0.4 2.9 2 0 0 2 2 2 0 M protein repeat tRNA-synt_1e PF01406.19 AMK75844.1 - 1.3e-134 448.3 0.0 1.7e-134 448.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 AMK75844.1 - 9.7e-21 74.0 1.7 9.7e-21 74.0 1.7 2.4 3 0 0 3 3 3 1 DALR domain tRNA-synt_1g PF09334.11 AMK75844.1 - 1.3e-12 47.2 0.2 2.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AMK75844.1 - 4.4e-08 31.9 0.0 5e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AMK75844.1 - 1.8e-07 30.4 0.1 3.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Mut7-C PF01927.16 AMK75844.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain Pro_isomerase PF00160.21 AMK75845.1 - 2e-48 164.7 0.2 2.3e-48 164.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Metallophos_2 PF12850.7 AMK75846.1 - 1.7e-08 34.8 0.4 4.8e-07 30.1 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AMK75846.1 - 6.1e-06 26.9 0.0 1.1e-05 26.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Trypsin_2 PF13365.6 AMK75847.1 - 1.4e-20 74.7 0.0 1.8e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AMK75847.1 - 1.6e-06 28.1 0.0 4.3e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S3 PF00944.19 AMK75847.1 - 0.062 13.1 0.1 6.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Alphavirus core protein Bac_transf PF02397.16 AMK75848.1 - 9.5e-66 220.9 0.0 1.8e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AMK75848.1 - 3.6e-08 33.6 0.6 3.6e-08 33.6 0.6 1.8 2 0 0 2 2 2 1 CoA-binding domain Mem_trans PF03547.18 AMK75848.1 - 0.11 10.9 2.6 0.2 10.0 2.6 1.3 1 0 0 1 1 1 0 Membrane transport protein 5TM-5TMR_LYT PF07694.12 AMK75848.1 - 2.1 7.8 9.4 0.19 11.2 4.5 1.7 2 0 0 2 2 2 0 5TMR of 5TMR-LYT DUF2070 PF09843.9 AMK75848.1 - 3.7 5.7 9.5 7.5 4.7 9.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATP_bind_3 PF01171.20 AMK75849.1 - 0.058 13.1 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 PP-loop family AMP-binding PF00501.28 AMK75850.1 - 5.1e-69 232.9 0.0 6.3e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AMK75850.1 - 0.024 15.6 0.0 0.07 14.1 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain NAD_binding_4 PF07993.12 AMK75851.1 - 2.3e-50 171.2 0.0 2.8e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 AMK75851.1 - 7.8e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK75851.1 - 4.3e-08 32.9 0.0 5.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AMK75851.1 - 4.9e-07 29.8 0.0 1.2e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 AMK75851.1 - 0.00012 21.3 0.0 0.00032 19.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 AMK75851.1 - 0.00025 21.0 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 AMK75851.1 - 0.0018 18.7 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 AMK75851.1 - 0.0086 15.2 0.4 0.07 12.2 0.4 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AMK75851.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 AMK75851.1 - 0.056 13.6 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 AMK75851.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Methyltransf_31 PF13847.6 AMK75852.1 - 2.6e-22 79.2 0.0 3.4e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK75852.1 - 2.3e-20 73.1 0.1 6.6e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK75852.1 - 6.9e-20 71.5 0.0 1.7e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK75852.1 - 3.3e-14 53.4 0.1 9.7e-14 51.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK75852.1 - 3.8e-11 43.1 0.0 5.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK75852.1 - 2.8e-10 39.9 0.0 5.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 AMK75852.1 - 3.4e-09 36.4 0.0 9.9e-09 34.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 AMK75852.1 - 3.2e-07 30.0 0.0 4.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 AMK75852.1 - 4.1e-06 26.7 0.0 6.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 AMK75852.1 - 2.7e-05 23.6 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 AMK75852.1 - 0.00024 20.5 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 AMK75852.1 - 0.00031 20.9 0.0 0.00052 20.2 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 AMK75852.1 - 0.00034 20.3 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 AMK75852.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 AMK75852.1 - 0.0074 16.3 0.0 0.085 12.8 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 AMK75852.1 - 0.013 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 AMK75852.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F UPF0020 PF01170.18 AMK75852.1 - 0.051 13.2 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PEP-CTERM PF07589.11 AMK75853.1 - 4.3e-07 29.7 0.5 4.3e-07 29.7 0.5 2.0 2 0 0 2 2 2 1 PEP-CTERM motif rve PF00665.26 AMK75855.1 - 2.1e-27 95.6 0.0 4.2e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK75855.1 - 2.1e-22 78.6 0.2 5e-22 77.5 0.2 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AMK75855.1 - 4.2e-07 30.0 0.5 7.6e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 HTH-like domain Rhomboid_SP PF12595.8 AMK75855.1 - 0.054 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Rhomboid serine protease DUF3108 PF11306.8 AMK75855.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) DDE_Tnp_1 PF01609.21 AMK75856.1 - 4.8e-31 108.1 2.7 7.4e-31 107.5 2.7 1.2 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK75856.1 - 3.5e-19 68.6 0.1 7.3e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_4 PF13359.6 AMK75856.1 - 2.2e-05 24.2 0.6 3.8e-05 23.4 0.6 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 AMK75856.1 - 0.00057 20.2 1.1 0.0014 19.0 1.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK75856.1 - 0.032 14.5 0.2 0.063 13.5 0.2 1.6 1 0 0 1 1 1 0 Transposase DDE domain VanZ PF04892.12 AMK75858.1 - 4.4e-33 114.6 40.1 2.8e-14 53.8 4.8 4.6 4 1 0 4 4 4 3 VanZ like family DUF3789 PF12664.7 AMK75858.1 - 0.11 12.3 3.1 0.55 10.0 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) ArAE_2_N PF10337.9 AMK75858.1 - 5.8 5.8 7.2 0.97 8.4 2.6 1.9 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal DHHA1 PF02272.19 AMK75859.1 - 1.5e-06 28.7 0.0 4.9e-06 27.0 0.0 1.8 3 0 0 3 3 3 1 DHHA1 domain DHH PF01368.20 AMK75859.1 - 0.035 14.4 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 DHH family APS_kinase PF01583.20 AMK75860.1 - 2.1e-69 232.4 0.0 2.7e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 AMK75860.1 - 8.7e-10 38.9 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AMK75860.1 - 0.00056 20.5 0.0 0.00083 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK75860.1 - 0.0028 18.2 0.0 0.0047 17.5 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 AMK75860.1 - 0.0039 16.5 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 AMK75860.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK75860.1 - 0.022 15.2 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 AMK75860.1 - 0.04 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 AMK75860.1 - 0.047 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 AMK75860.1 - 0.066 13.5 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 AMK75860.1 - 0.083 12.9 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 AMK75860.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 AMK75860.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNase_Zc3h12a PF11977.8 AMK75860.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain DUF87 PF01935.17 AMK75860.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 AMK75860.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dus PF01207.17 AMK75861.1 - 1.8e-101 339.3 0.0 2.1e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 AMK75861.1 - 1.5e-05 24.4 0.1 0.067 12.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase His_biosynth PF00977.21 AMK75861.1 - 3.5e-05 23.4 0.1 0.00036 20.1 0.0 2.1 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 AMK75861.1 - 0.0018 17.8 0.8 0.0048 16.3 0.1 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase SOR_SNZ PF01680.17 AMK75861.1 - 0.0019 18.0 1.4 0.068 12.9 0.1 2.2 1 1 1 2 2 2 1 SOR/SNZ family NanE PF04131.14 AMK75861.1 - 0.0028 16.9 0.1 0.0083 15.3 0.0 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 AMK75861.1 - 0.025 13.9 0.1 0.05 12.9 0.1 1.6 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 AMK75861.1 - 0.068 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 AMK75861.1 - 0.084 12.3 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Oxidored_FMN PF00724.20 AMK75861.1 - 0.091 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family HTH_8 PF02954.19 AMK75862.1 - 1e-14 54.0 0.0 1.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 AMK75862.1 - 0.0043 16.8 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 AMK75862.1 - 0.0062 16.1 0.3 0.023 14.3 0.1 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain UPF0175 PF03683.13 AMK75862.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_psq PF05225.16 AMK75862.1 - 0.08 12.7 0.1 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_28 PF13518.6 AMK75862.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AICARFT_IMPCHas PF01808.18 AMK75863.1 - 1.8e-118 395.3 2.6 2.2e-118 395.0 2.6 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 AMK75863.1 - 2.9e-28 97.9 0.0 1.1e-27 96.0 0.0 2.0 2 0 0 2 2 2 1 MGS-like domain SlpA PF03217.14 AMK75863.1 - 0.27 11.9 1.5 0.65 10.6 0.5 2.0 2 0 0 2 2 2 0 Surface later protein A domain GARS_A PF01071.19 AMK75864.1 - 1.4e-79 266.4 0.1 1.9e-79 266.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AMK75864.1 - 2.4e-35 121.2 0.5 1.3e-34 118.9 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AMK75864.1 - 6.7e-30 103.2 0.3 2.7e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 AMK75864.1 - 4.8e-07 29.5 0.0 7.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 AMK75864.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AMK75864.1 - 0.00027 21.0 0.0 0.00045 20.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AMK75864.1 - 0.0028 17.3 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AMK75864.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AMK75864.1 - 0.011 15.3 0.1 0.032 13.7 0.1 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.10 AMK75864.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain YhzD PF14120.6 AMK75864.1 - 0.15 12.2 0.4 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 YhzD-like protein DPBB_1 PF03330.18 AMK75865.1 - 1.2e-18 67.1 0.0 1.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Lytic transglycolase SirB PF04247.12 AMK75866.1 - 9.7e-29 99.9 11.8 1.1e-28 99.8 11.8 1.0 1 0 0 1 1 1 1 Invasion gene expression up-regulator, SirB LrgA PF03788.14 AMK75866.1 - 0.11 12.5 8.9 0.032 14.2 2.9 2.1 1 1 1 2 2 2 0 LrgA family DUF2157 PF09925.9 AMK75866.1 - 3.5 7.4 13.7 1 9.2 10.5 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF3792 PF12670.7 AMK75866.1 - 4.7 7.4 14.9 0.4 10.9 8.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Tex_N PF09371.10 AMK75868.1 - 4.9e-72 241.4 0.4 8.5e-72 240.6 0.4 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 AMK75868.1 - 1.7e-54 183.6 0.0 3.7e-54 182.5 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 AMK75868.1 - 2.3e-28 98.2 0.4 5.4e-28 97.0 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_9 PF17674.1 AMK75868.1 - 1.2e-24 87.0 0.0 5e-24 85.0 0.0 2.2 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 AMK75868.1 - 2.8e-22 78.8 0.8 5.5e-22 77.9 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_7 PF14635.6 AMK75868.1 - 4e-08 33.5 0.0 1.1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 AMK75868.1 - 5.6e-08 32.7 0.0 2.4e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_6 PF14579.6 AMK75868.1 - 0.02 15.2 0.0 0.096 13.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif PsbU PF06514.11 AMK75868.1 - 0.029 14.3 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) RNase_II_C_S1 PF18614.1 AMK75868.1 - 0.23 11.5 5.7 0.76 9.8 2.1 2.9 2 1 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain AAA_23 PF13476.6 AMK75870.1 - 2e-16 61.1 18.9 2e-16 61.1 18.9 7.3 1 1 4 5 5 5 1 AAA domain SMC_N PF02463.19 AMK75870.1 - 1.9e-13 50.4 0.0 3e-12 46.5 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AMK75870.1 - 1.3e-12 47.8 0.2 3.2e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 AMK75870.1 - 3.2e-06 26.8 0.0 8.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AMK75870.1 - 6.2e-05 22.9 0.4 6.2e-05 22.9 0.4 3.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 AMK75870.1 - 0.00022 21.1 0.0 0.00062 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Suv3_N PF18114.1 AMK75870.1 - 0.00093 19.3 0.0 0.0055 16.8 0.0 2.4 1 0 0 1 1 1 1 Suv3 helical N-terminal domain ABC_tran PF00005.27 AMK75870.1 - 0.022 15.3 0.0 0.022 15.3 0.0 5.3 3 2 0 3 3 3 0 ABC transporter PYC_OADA PF02436.18 AMK75870.1 - 0.31 10.7 2.4 0.91 9.2 0.0 3.1 2 1 1 3 3 3 0 Conserved carboxylase domain Fez1 PF06818.15 AMK75870.1 - 1.6 9.1 64.6 1.6 9.1 10.1 5.8 2 1 2 5 5 5 0 Fez1 TPR_8 PF13181.6 AMK75871.1 - 1.1e-05 25.2 0.3 0.0061 16.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75871.1 - 0.00013 21.8 0.4 0.00079 19.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75871.1 - 0.00037 20.2 0.2 0.0036 17.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 AMK75871.1 - 0.0058 15.6 0.2 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 AMK75871.1 - 0.0061 17.1 0.1 0.014 15.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75871.1 - 0.0093 16.6 0.5 0.038 14.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75871.1 - 0.011 16.5 0.1 0.047 14.5 0.0 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 AMK75871.1 - 0.012 15.8 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK75871.1 - 0.012 15.8 0.1 0.091 13.0 0.1 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 AMK75871.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region SRP_TPR_like PF17004.5 AMK75871.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_15 PF13429.6 AMK75871.1 - 0.086 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 AMK75871.1 - 0.12 12.8 0.1 16 6.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Asn_synthase PF00733.21 AMK75872.1 - 3.2e-77 260.6 0.1 3.9e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AMK75872.1 - 0.00026 20.9 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AMK75872.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 AMK75872.1 - 0.052 12.7 0.0 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD synthase AMP-binding PF00501.28 AMK75873.1 - 4.8e-09 35.3 0.1 1.5e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Glycos_transf_1 PF00534.20 AMK75874.1 - 6.7e-35 120.1 0.0 8.9e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK75874.1 - 6.3e-26 91.4 0.1 1.1e-25 90.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK75874.1 - 4.3e-14 52.9 0.0 8.5e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK75874.1 - 3.2e-09 37.4 0.1 6.8e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AMK75874.1 - 1.5e-05 25.3 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 AMK75874.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_2 PF13477.6 AMK75874.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glycos_transf_1 PF00534.20 AMK75875.1 - 3e-29 101.8 0.0 4.4e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK75875.1 - 2.1e-28 99.4 0.0 3.6e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK75875.1 - 6.9e-22 78.6 0.1 1.7e-21 77.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AMK75875.1 - 1e-21 77.7 0.2 1.8e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK75875.1 - 3.1e-10 40.3 0.2 6e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AMK75875.1 - 0.00029 20.9 0.1 0.00045 20.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Nbas_N PF15492.6 AMK75875.1 - 0.023 14.0 0.0 0.096 12.0 0.0 1.8 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal NTP_transf_5 PF14907.6 AMK75876.1 - 1.3e-43 149.4 1.1 1.6e-43 149.1 1.1 1.1 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase Hpr_kinase_C PF07475.12 AMK75877.1 - 9.8e-05 21.9 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 AMK75877.1 - 0.0046 16.7 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AMK75877.1 - 0.01 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AMK75877.1 - 0.012 15.8 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AMK75877.1 - 0.017 15.7 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 AMK75877.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 AMK75877.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 AMK75877.1 - 0.038 14.5 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 AMK75877.1 - 0.051 13.9 0.0 0.079 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AMK75877.1 - 0.055 13.6 0.0 0.069 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AMK75877.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AMK75877.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 AMK75877.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 AMK75877.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family MeaB PF03308.16 AMK75877.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 AMK75877.1 - 0.2 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 AMK75877.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TraD PF06412.11 AMK75878.1 - 0.18 11.6 0.3 0.26 11.1 0.3 1.2 1 0 0 1 1 1 0 Conjugal transfer protein TraD Asn_synthase PF00733.21 AMK75879.1 - 2.3e-99 333.5 0.1 2.8e-99 333.2 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AMK75879.1 - 7.8e-51 171.1 0.0 1.3e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AMK75879.1 - 1.1e-44 151.9 0.0 4.8e-44 149.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AMK75879.1 - 0.00019 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 AMK75879.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Glyco_trans_1_4 PF13692.6 AMK75880.1 - 7.8e-30 104.0 0.0 1.6e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK75880.1 - 3.7e-29 101.5 0.0 6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK75880.1 - 7.4e-20 71.6 0.3 1.1e-19 71.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK75880.1 - 1.2e-11 44.8 0.0 3.6e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK75880.1 - 1.3e-08 35.4 0.0 2.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AMK75880.1 - 0.00072 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_4 PF13692.6 AMK75881.1 - 2.4e-32 112.2 0.8 4e-32 111.4 0.8 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK75881.1 - 1.7e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK75881.1 - 2.5e-05 24.3 0.0 8.1e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK75881.1 - 0.001 19.4 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Acetyltransf_6 PF13480.7 AMK75882.1 - 1.8e-15 57.3 0.1 4.8e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FemAB PF02388.16 AMK75882.1 - 2.9e-09 36.3 0.9 9.7e-07 28.0 0.1 3.0 1 1 1 3 3 3 2 FemAB family FemAB_like PF04339.12 AMK75882.1 - 1.7e-07 30.7 0.3 2.7e-07 30.1 0.3 1.4 1 1 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition DUF3473 PF11959.8 AMK75883.1 - 3.6e-53 179.0 0.1 6.3e-53 178.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) Polysacc_deac_1 PF01522.21 AMK75883.1 - 6.5e-24 84.2 0.0 9.4e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 AMK75883.1 - 0.00096 18.9 0.1 0.0021 17.7 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Epimerase_2 PF02350.19 AMK75884.1 - 1.6e-110 369.3 0.0 1.9e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_9 PF01075.17 AMK75884.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) AAA_22 PF13401.6 AMK75885.1 - 1.5e-18 67.3 0.2 4.9e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK75885.1 - 3.6e-09 37.2 2.3 0.00037 20.9 0.1 3.0 2 2 2 4 4 4 2 AAA ATPase domain AAA_19 PF13245.6 AMK75885.1 - 5.2e-07 30.1 0.6 2e-06 28.2 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 AMK75885.1 - 2.1e-06 28.2 0.1 5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AMK75885.1 - 6.5e-06 25.7 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AMK75885.1 - 7.4e-06 25.8 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AMK75885.1 - 1.2e-05 24.9 0.1 2.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 AMK75885.1 - 7.1e-05 22.9 0.2 0.0002 21.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 AMK75885.1 - 8.6e-05 21.9 0.2 0.00015 21.1 0.0 1.4 2 0 0 2 2 1 1 PIF1-like helicase DUF2075 PF09848.9 AMK75885.1 - 0.00013 21.3 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 AMK75885.1 - 0.00015 21.8 0.1 0.025 14.5 0.1 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 AMK75885.1 - 0.00016 21.7 1.6 0.00032 20.7 0.4 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AMK75885.1 - 0.00051 20.0 4.5 0.00082 19.3 2.0 2.3 2 1 0 2 2 1 1 NACHT domain ATPase PF06745.13 AMK75885.1 - 0.001 18.4 0.2 0.0035 16.7 0.2 1.9 1 1 1 2 2 2 1 KaiC PhoH PF02562.16 AMK75885.1 - 0.0016 17.9 0.3 1.4 8.4 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 AMK75885.1 - 0.0027 17.6 0.1 0.0058 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain MobB PF03205.14 AMK75885.1 - 0.003 17.5 0.9 0.0054 16.6 0.1 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B UvrD-helicase PF00580.21 AMK75885.1 - 0.005 16.4 1.1 0.44 10.0 0.2 2.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 AMK75885.1 - 0.0052 17.0 0.1 0.0086 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AMK75885.1 - 0.006 17.0 0.1 0.042 14.3 0.0 2.3 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 AMK75885.1 - 0.01 15.7 0.3 0.025 14.5 0.3 1.8 1 1 0 1 1 1 0 NTPase cobW PF02492.19 AMK75885.1 - 0.013 15.0 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 AMK75885.1 - 0.014 15.4 0.1 0.32 11.0 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AMK75885.1 - 0.018 14.6 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AMK75885.1 - 0.02 14.0 0.2 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_32 PF13654.6 AMK75885.1 - 0.03 13.1 0.0 0.077 11.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 AMK75885.1 - 0.031 13.5 0.1 0.057 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 AMK75885.1 - 0.033 14.1 0.1 0.098 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AMK75885.1 - 0.04 14.4 0.4 0.11 13.0 0.3 2.2 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 AMK75885.1 - 0.048 13.1 0.7 0.39 10.1 0.7 2.2 1 1 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 AMK75885.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 AMK75885.1 - 0.065 13.8 0.7 0.65 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 AMK75885.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 AMK75885.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 AMK75885.1 - 0.072 12.7 0.0 0.072 12.7 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 AMK75885.1 - 0.075 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 AMK75885.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AMK75885.1 - 0.095 12.7 0.1 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 AMK75885.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 AMK75885.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 AMK75885.1 - 0.11 11.4 0.6 0.47 9.3 0.1 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 AMK75885.1 - 0.15 12.3 0.7 0.34 11.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AMK75885.1 - 0.23 11.5 2.3 0.18 11.8 0.4 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_31 PF13614.6 AMK75887.1 - 8.8e-11 42.0 0.9 2.5e-10 40.5 0.5 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 AMK75887.1 - 2.2e-08 34.2 0.0 3.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AMK75887.1 - 6.2e-08 32.4 0.2 2e-07 30.7 0.2 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DnaB_C PF03796.15 AMK75887.1 - 0.0027 17.1 0.0 0.0066 15.8 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain SRP54 PF00448.22 AMK75887.1 - 0.025 14.2 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 AMK75887.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.5 1 1 0 1 1 1 0 KaiC ResIII PF04851.15 AMK75887.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GNVR PF13807.6 AMK75888.1 - 8.7e-07 28.8 0.1 3.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 G-rich domain on putative tyrosine kinase SLATT_5 PF18160.1 AMK75888.1 - 0.0031 16.9 0.0 0.0097 15.3 0.0 1.8 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 PLRV_ORF5 PF01690.17 AMK75888.1 - 0.017 13.9 0.2 0.03 13.1 0.2 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Poxvirus_B22R PF04395.12 AMK75888.1 - 0.05 13.2 1.9 0.31 10.6 0.2 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein Wzz PF02706.15 AMK75888.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.7 4 0 0 4 4 4 0 Chain length determinant protein GPW_gp25 PF04965.14 AMK75888.1 - 0.14 11.9 1.0 0.74 9.6 0.0 2.7 3 0 0 3 3 3 0 Gene 25-like lysozyme DUF5610 PF18433.1 AMK75888.1 - 0.15 12.6 6.3 0.53 10.8 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) GAS PF13851.6 AMK75888.1 - 1.4 8.2 19.8 0.2 11.0 6.3 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Poly_export PF02563.16 AMK75889.1 - 2.2e-21 75.9 0.0 4.1e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis/export protein TPR_19 PF14559.6 AMK75890.1 - 1.2e-39 134.6 44.1 1.5e-06 28.6 0.5 12.1 8 3 4 12 12 12 9 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75890.1 - 1.4e-34 118.4 0.4 8.4e-05 23.1 0.6 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75890.1 - 2.2e-34 114.8 33.8 0.00015 21.6 0.2 16.0 18 0 0 18 18 16 7 Tetratricopeptide repeat TPR_14 PF13428.6 AMK75890.1 - 6.7e-34 113.7 14.5 0.029 15.2 0.1 15.6 8 5 11 19 19 16 7 Tetratricopeptide repeat TPR_8 PF13181.6 AMK75890.1 - 1.3e-22 78.0 46.4 3.1e-05 23.8 0.2 14.8 16 0 0 16 16 14 6 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75890.1 - 5.6e-22 76.6 45.1 0.00019 21.1 0.3 12.6 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75890.1 - 6.6e-20 71.2 30.4 1.2e-07 31.9 1.1 10.4 8 3 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 AMK75890.1 - 9.9e-20 69.8 29.0 0.0046 17.5 0.0 12.7 12 1 0 12 12 12 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK75890.1 - 4.5e-16 58.8 25.2 0.00012 22.2 0.5 8.0 4 1 5 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AMK75890.1 - 1.6e-15 55.9 17.0 0.063 13.3 0.0 10.7 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 AMK75890.1 - 2.6e-12 46.2 29.9 0.018 15.4 0.1 13.4 14 1 0 14 14 12 2 Tetratricopeptide repeat TPR_9 PF13371.6 AMK75890.1 - 6.9e-11 42.1 0.1 0.96 9.6 0.0 7.2 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75890.1 - 2.9e-08 33.3 44.7 0.13 12.0 0.7 11.5 9 4 5 14 14 14 4 TPR repeat ChAPs PF09295.10 AMK75890.1 - 3.7e-08 32.8 14.9 0.025 13.6 0.1 4.9 2 1 2 5 5 5 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 AMK75890.1 - 3e-07 30.1 26.6 0.31 11.0 0.6 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_20 PF14561.6 AMK75890.1 - 1.3e-06 28.7 30.4 1.2 9.6 2.2 9.8 6 3 5 11 11 11 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AMK75890.1 - 2e-05 24.2 2.3 0.046 13.4 0.1 5.2 4 2 0 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 AMK75890.1 - 0.00043 19.8 21.7 0.054 12.9 0.6 6.5 4 3 1 5 5 5 2 MalT-like TPR region TPPII_N PF12583.8 AMK75890.1 - 0.0017 19.0 5.5 1.6 9.3 0.1 4.7 4 1 1 5 5 5 1 Tripeptidyl peptidase II N terminal PPR PF01535.20 AMK75890.1 - 0.0022 18.1 0.2 7.6 7.0 0.0 6.2 6 1 1 7 7 6 0 PPR repeat TPR_21 PF09976.9 AMK75890.1 - 0.0027 17.5 1.5 0.0027 17.5 1.5 7.1 3 3 5 8 8 8 3 Tetratricopeptide repeat-like domain Fis1_TPR_N PF14852.6 AMK75890.1 - 0.0044 16.7 1.7 0.38 10.5 0.4 3.0 2 1 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat BTAD PF03704.17 AMK75890.1 - 0.0055 17.1 2.0 14 6.1 0.0 5.4 5 1 3 8 8 6 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 AMK75890.1 - 0.0073 16.3 4.0 0.048 13.6 0.3 3.6 3 1 2 5 5 4 1 Virulence factor membrane-bound polymerase, C-terminal NRDE-2 PF08424.10 AMK75890.1 - 0.01 15.0 0.0 0.01 15.0 0.0 3.0 3 1 1 4 4 4 0 NRDE-2, necessary for RNA interference PknG_TPR PF16918.5 AMK75890.1 - 0.027 13.2 4.6 6.7 5.3 0.1 4.0 2 1 3 5 5 5 0 Protein kinase G tetratricopeptide repeat DUF4919 PF16266.5 AMK75890.1 - 0.14 12.1 0.1 0.14 12.1 0.1 4.6 5 1 2 7 7 7 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 AMK75890.1 - 0.49 10.4 8.0 0.88 9.6 0.4 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat CID_GANP PF16766.5 AMK75890.1 - 1.1 9.5 3.6 4.8 7.5 0.3 3.2 3 0 0 3 3 2 0 Binding region of GANP to ENY2 MIT PF04212.18 AMK75890.1 - 9.2 6.4 20.3 0.74 9.9 0.5 6.3 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Acetyltransf_5 PF13444.6 AMK75891.1 - 4.2e-17 62.7 0.2 6.2e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 AMK75891.1 - 0.00017 21.2 0.1 0.079 12.5 0.1 2.4 2 1 0 2 2 2 2 Autoinducer synthase DUF2555 PF10742.9 AMK75891.1 - 0.035 13.9 0.2 0.081 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Ycf54 PF10674.9 AMK75891.1 - 0.048 13.9 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) cNMP_binding PF00027.29 AMK75892.1 - 2.8e-12 46.6 0.0 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HATPase_c PF02518.26 AMK75893.1 - 2.6e-18 66.5 0.0 6.5e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 AMK75893.1 - 1.4e-06 28.2 0.0 3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 AMK75893.1 - 6.6e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain Not3 PF04065.15 AMK75893.1 - 0.13 11.7 0.9 0.16 11.3 0.3 1.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Sigma54_activat PF00158.26 AMK75894.1 - 8.8e-70 233.8 0.0 1.4e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK75894.1 - 3e-27 95.4 0.0 7.8e-27 94.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK75894.1 - 1.5e-17 63.8 0.0 3.3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AMK75894.1 - 2.3e-09 36.9 0.4 9.5e-09 34.9 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK75894.1 - 1.7e-07 31.3 0.0 4.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK75894.1 - 5e-05 23.7 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AMK75894.1 - 0.00011 21.7 0.2 0.17 11.3 0.1 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AMK75894.1 - 0.0022 18.2 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HTH_17 PF12728.7 AMK75894.1 - 0.0054 16.9 0.0 0.021 15.0 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AMK75894.1 - 0.0084 16.2 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75894.1 - 0.0099 15.6 0.0 0.061 13.1 0.0 2.4 2 1 0 2 2 2 1 Homeodomain-like domain AAA_16 PF13191.6 AMK75894.1 - 0.015 15.7 0.1 0.053 13.9 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 AMK75894.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 AMK75894.1 - 0.032 13.5 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 AMK75894.1 - 0.095 12.4 0.8 0.22 11.2 0.1 2.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 AMK75894.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein HTH_29 PF13551.6 AMK75894.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF5616 PF18481.1 AMK75894.1 - 0.16 12.3 0.0 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) Acetyltransf_5 PF13444.6 AMK75895.1 - 1.9e-15 57.4 0.6 3.6e-15 56.5 0.6 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 AMK75895.1 - 0.0026 17.3 0.1 0.061 12.9 0.1 2.1 2 0 0 2 2 2 1 Autoinducer synthase DUF2126 PF09899.9 AMK75896.1 - 0 1351.5 0.0 0 1351.3 0.0 1.0 1 0 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) Bact_transglu_N PF08379.10 AMK75896.1 - 2.9e-30 105.0 0.3 8.1e-30 103.6 0.3 1.9 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AMK75896.1 - 7.7e-17 61.8 0.0 1.4e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Glyoxalase_4 PF13669.6 AMK75897.1 - 0.08 13.2 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Alpha-E PF04168.12 AMK75898.1 - 3e-102 342.4 7.9 3.4e-102 342.2 7.9 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. CP_ATPgrasp_2 PF14403.6 AMK75899.1 - 4.8e-163 542.4 0.0 5.6e-163 542.2 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AMK75899.1 - 1.5e-158 527.1 0.3 1.5e-158 527.1 0.3 1.4 2 0 0 2 2 2 1 A circularly permuted ATPgrasp ATPgrasp_ST PF14397.6 AMK75899.1 - 0.094 11.9 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PfkB PF00294.24 AMK75901.1 - 1.7e-42 145.8 0.0 2.3e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4418 PF14387.6 AMK75902.1 - 0.002 18.3 4.4 0.13 12.5 2.4 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4418) HlyD_D23 PF16576.5 AMK75903.1 - 1.7e-17 63.3 4.6 5.7e-16 58.4 4.6 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK75903.1 - 1.7e-15 57.6 1.2 4.3e-14 53.1 0.0 2.9 2 1 0 3 3 3 1 HlyD family secretion protein HlyD PF00529.20 AMK75903.1 - 2.6e-09 36.8 0.1 3.8e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AMK75903.1 - 2.2e-07 30.6 1.3 0.00032 20.4 0.6 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK75903.1 - 0.00081 19.2 0.1 0.47 10.3 0.0 2.6 3 0 0 3 3 2 2 Biotin-requiring enzyme HOOK PF05622.12 AMK75903.1 - 0.0018 16.5 3.3 0.0024 16.1 3.3 1.1 1 0 0 1 1 1 1 HOOK protein Fez1 PF06818.15 AMK75903.1 - 0.028 14.9 3.6 0.044 14.2 3.6 1.2 1 0 0 1 1 1 0 Fez1 HR1 PF02185.16 AMK75903.1 - 0.067 13.3 3.2 4.6 7.4 0.6 2.9 2 0 0 2 2 2 0 Hr1 repeat Snapin_Pallidin PF14712.6 AMK75903.1 - 0.081 13.3 3.0 2.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 AMK75903.1 - 0.086 11.7 4.5 0.12 11.2 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 AMK75903.1 - 0.14 12.1 3.5 0.26 11.3 3.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 AMK75903.1 - 0.18 10.9 2.6 0.25 10.4 2.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Flagellin_N PF00669.20 AMK75903.1 - 0.2 11.8 6.4 3.1 7.9 4.6 2.3 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region SANTA PF09133.10 AMK75903.1 - 0.22 12.0 0.1 3.6 8.1 0.0 2.3 2 0 0 2 2 2 0 SANTA (SANT Associated) Seryl_tRNA_N PF02403.22 AMK75903.1 - 0.45 10.8 6.9 1 9.6 6.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 AMK75903.1 - 3.8 8.0 9.4 25 5.4 8.8 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region OEP PF02321.18 AMK75904.1 - 3.5e-34 118.2 25.1 4.9e-17 62.4 1.6 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein KapB PF08810.10 AMK75904.1 - 0.17 12.0 0.4 4.8 7.4 0.1 2.8 2 1 0 2 2 2 0 Kinase associated protein B MFS_1 PF07690.16 AMK75905.1 - 1.2e-38 133.0 48.9 1.8e-36 125.8 46.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 AMK75905.1 - 5.6e-05 21.8 8.4 9.3e-05 21.0 8.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HTH_1 PF00126.27 AMK75907.1 - 3.8e-19 68.4 0.3 1.1e-18 66.9 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AMK75907.1 - 5.9e-19 68.3 3.2 2.4e-18 66.3 1.1 2.4 2 1 0 2 2 2 1 LysR substrate binding domain HTH_30 PF13556.6 AMK75907.1 - 6.5e-05 22.7 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AMK75907.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AMK75907.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 AMK75907.1 - 0.089 12.7 0.2 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 MarR family NAD_binding_1 PF00175.21 AMK75908.1 - 1.7e-14 54.4 0.0 3.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AMK75908.1 - 1.9e-13 50.1 2.8 4e-13 49.1 2.8 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 AMK75908.1 - 1.5e-11 44.5 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.6 AMK75908.1 - 5.2e-05 23.2 0.3 0.00012 22.0 0.3 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 AMK75908.1 - 0.041 14.0 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Bac_globin PF01152.21 AMK75909.1 - 6.5e-19 68.3 0.0 7.8e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 AMK75909.1 - 3.8e-05 23.6 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protoglobin HTH_11 PF08279.12 AMK75910.1 - 3.3e-09 36.6 0.5 7.8e-09 35.4 0.5 1.6 1 0 0 1 1 1 1 HTH domain MetOD1 PF18546.1 AMK75910.1 - 6.9e-06 26.1 0.1 1.1e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Metanogen output domain 1 HTH_24 PF13412.6 AMK75910.1 - 1.3e-05 24.6 0.4 2.7e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 AMK75910.1 - 1.7e-05 24.6 0.6 3.9e-05 23.4 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family PadR PF03551.14 AMK75910.1 - 3.2e-05 23.8 0.1 6.9e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_IclR PF09339.10 AMK75910.1 - 3.3e-05 23.6 0.4 8.9e-05 22.2 0.4 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_34 PF13601.6 AMK75910.1 - 3.5e-05 23.9 0.0 6.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Sigma70_r4_2 PF08281.12 AMK75910.1 - 4.3e-05 23.1 0.1 0.00014 21.4 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 AMK75910.1 - 0.00031 20.8 0.2 0.00074 19.5 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3489 PF11994.8 AMK75910.1 - 0.00032 20.7 1.0 0.00059 19.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3489) HTH_Mga PF08280.11 AMK75910.1 - 0.00044 20.2 0.3 0.0011 19.0 0.3 1.7 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_DeoR PF08220.12 AMK75910.1 - 0.00074 19.2 0.5 0.0018 18.0 0.5 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HxlR PF01638.17 AMK75910.1 - 0.00089 19.1 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Sigma70_r4 PF04545.16 AMK75910.1 - 0.001 18.6 0.1 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 GntR PF00392.21 AMK75910.1 - 0.0023 17.5 0.7 0.0045 16.6 0.3 1.7 2 0 0 2 2 1 1 Bacterial regulatory proteins, gntR family Sigma70_ECF PF07638.11 AMK75910.1 - 0.0038 17.1 0.1 0.0077 16.1 0.1 1.5 1 0 0 1 1 1 1 ECF sigma factor GerE PF00196.19 AMK75910.1 - 0.0046 16.5 0.1 0.0089 15.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family MarR_2 PF12802.7 AMK75910.1 - 0.0049 16.7 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AMK75910.1 - 0.0052 17.1 0.2 0.01 16.2 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 AMK75910.1 - 0.0077 16.1 0.5 0.018 15.0 0.2 1.7 2 0 0 2 2 1 1 MarR family HTH_10 PF04967.12 AMK75910.1 - 0.012 15.4 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain GcrA PF07750.11 AMK75910.1 - 0.012 16.0 0.2 0.016 15.6 0.2 1.5 1 1 0 1 1 1 0 GcrA cell cycle regulator RPA_C PF08784.11 AMK75910.1 - 0.015 15.9 0.1 0.034 14.8 0.1 1.6 1 0 0 1 1 1 0 Replication protein A C terminal HTH_28 PF13518.6 AMK75910.1 - 0.016 15.3 0.0 0.048 13.8 0.0 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 AMK75910.1 - 0.016 14.9 0.6 0.12 12.2 0.3 2.4 2 0 0 2 2 2 0 LexA DNA binding domain UPF0122 PF04297.14 AMK75910.1 - 0.021 15.1 0.1 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Mga PF05043.13 AMK75910.1 - 0.022 15.4 0.3 0.064 13.9 0.1 1.8 2 1 0 2 2 2 0 Mga helix-turn-helix domain HTH_23 PF13384.6 AMK75910.1 - 0.024 14.4 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_12 PF08461.10 AMK75910.1 - 0.025 14.5 0.3 0.069 13.1 0.1 1.9 2 0 0 2 2 1 0 Ribonuclease R winged-helix domain TnsD PF15978.5 AMK75910.1 - 0.026 13.5 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D DprA_WH PF17782.1 AMK75910.1 - 0.038 14.1 1.8 0.051 13.7 0.5 1.9 2 0 0 2 2 1 0 DprA winged helix domain TrmB PF01978.19 AMK75910.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_40 PF14493.6 AMK75910.1 - 0.076 13.5 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 AMK75910.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_30 PF13556.6 AMK75910.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Peptidase_S11 PF00768.20 AMK75911.1 - 2.1e-86 289.3 0.1 2.8e-86 288.9 0.1 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 AMK75911.1 - 4.5e-18 65.3 0.0 7.6e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 AMK75911.1 - 2.7e-16 59.8 0.1 3.9e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 AMK75911.1 - 0.00083 18.2 0.2 0.0027 16.5 0.0 1.7 1 1 1 2 2 2 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase PF00144.24 AMK75911.1 - 0.0022 17.3 0.2 0.022 14.0 0.1 2.1 1 1 1 2 2 2 1 Beta-lactamase Transpeptidase PF00905.22 AMK75911.1 - 0.0085 15.3 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain Aminotran_4 PF01063.19 AMK75912.1 - 2.8e-44 151.6 0.0 3.2e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV DUF493 PF04359.14 AMK75913.1 - 1.4e-31 108.9 0.0 1.6e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Cucumopine_C PF18631.1 AMK75913.1 - 0.061 13.3 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain BPL_LplA_LipB PF03099.19 AMK75914.1 - 7.9e-08 32.3 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Radical_SAM PF04055.21 AMK75915.1 - 6e-13 49.5 0.0 9.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 AMK75915.1 - 4.6e-12 46.3 0.2 8.7e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family DUF1877 PF08974.10 AMK75916.1 - 0.21 11.7 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) HTH_Tnp_1 PF01527.20 AMK75917.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK75917.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK75917.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75917.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK75917.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK75917.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK75918.1 - 1.9e-26 92.6 0.1 3.9e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AMK75918.1 - 9.6e-06 25.7 2.8 2.1e-05 24.6 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_IS240 PF13610.6 AMK75918.1 - 0.00026 21.2 0.7 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 DDE domain rve PF00665.26 AMK75919.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK75919.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK75919.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK75919.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK75919.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK75919.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK75919.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 HTH_Tnp_1 PF01527.20 AMK75920.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK75920.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK75920.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK75920.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK75920.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK75920.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF772 PF05598.11 AMK75921.1 - 2.4e-22 78.7 0.7 3e-21 75.2 0.3 2.9 2 1 1 3 3 3 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AMK75921.1 - 3.1e-14 53.1 0.5 8.8e-14 51.7 0.5 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK75921.1 - 5.2e-10 39.6 0.1 1.2e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AMK75921.1 - 2.9e-05 24.3 0.0 6.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK75921.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Phage_integrase PF00589.22 AMK75922.1 - 1.3e-11 44.6 0.2 3e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family YgbB PF02542.16 AMK75922.1 - 0.011 16.1 0.1 0.062 13.6 0.0 2.0 2 0 0 2 2 2 0 YgbB family Phage_int_SAM_1 PF02899.17 AMK75922.1 - 0.021 15.1 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PhdYeFM_antitox PF02604.19 AMK75923.1 - 0.03 14.1 0.0 0.038 13.8 0.0 1.3 1 1 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system CDC48_N PF02359.18 AMK75923.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain PIN PF01850.21 AMK75924.1 - 6.2e-11 42.9 0.0 6.9e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.6 AMK75924.1 - 0.035 14.0 0.1 0.11 12.5 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) PhdYeFM_antitox PF02604.19 AMK75926.1 - 2.9e-11 43.0 0.0 3.3e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PBP PF01161.20 AMK75927.1 - 2e-40 138.2 0.1 2.3e-40 137.9 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1993 PF09351.10 AMK75928.1 - 3.3e-64 215.9 0.1 3.7e-64 215.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) SusD-like_2 PF12771.7 AMK75928.1 - 0.041 12.8 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane ParD_antitoxin PF03693.14 AMK75929.1 - 7.5e-08 32.7 0.1 9.9e-08 32.3 0.1 1.3 1 1 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH RHH_8 PF17723.1 AMK75929.1 - 0.00031 20.9 0.1 0.00035 20.7 0.1 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family HTH_10 PF04967.12 AMK75929.1 - 0.015 15.1 0.6 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain ParE_toxin PF05016.15 AMK75930.1 - 5e-16 59.1 0.1 5.4e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE CLTH PF10607.9 AMK75930.1 - 0.021 14.7 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DEAD PF00270.29 AMK75931.1 - 5.7e-11 42.5 0.5 1.2e-10 41.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AMK75931.1 - 2.4e-05 24.4 0.3 6.7e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 AMK75931.1 - 0.0069 15.9 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein Helicase_C PF00271.31 AMK75931.1 - 0.01 16.1 0.0 0.037 14.4 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF1837 PF08878.11 AMK75932.1 - 2e-34 119.4 7.6 2.4e-34 119.2 7.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1837) UpxZ PF06603.11 AMK75932.1 - 0.1 12.9 0.3 13 6.1 0.1 2.4 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists ParD_antitoxin PF03693.14 AMK75933.1 - 2.8e-07 30.8 0.0 3.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH RHH_8 PF17723.1 AMK75933.1 - 0.0019 18.4 0.0 0.002 18.3 0.0 1.3 1 1 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family Trimer_CC PF08954.11 AMK75933.1 - 0.099 12.2 0.6 0.19 11.3 0.1 1.7 2 0 0 2 2 2 0 Trimerisation motif DUF1375 PF07119.12 AMK75934.1 - 1e-07 32.2 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) Phage_holin_3_6 PF07332.11 AMK75935.1 - 1.1 9.3 6.8 2.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF45 PF01863.17 AMK75936.1 - 3.5e-56 190.5 0.4 4e-56 190.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AMK75936.1 - 0.00035 20.7 0.1 0.00075 19.6 0.1 1.5 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 AMK75936.1 - 0.0018 18.1 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 SprT-like family SWI2_SNF2 PF18766.1 AMK75937.1 - 1.2e-84 283.5 0.1 2.3e-83 279.3 0.1 2.5 2 0 0 2 2 2 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 AMK75937.1 - 1.3e-34 119.8 0.3 5.9e-34 117.7 0.0 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 AMK75937.1 - 9.3e-21 74.6 0.0 2.7e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3387 PF11867.8 AMK75937.1 - 6.1e-14 52.1 10.2 1.3e-13 51.1 10.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) T3SchapCesA PF11439.8 AMK75937.1 - 0.022 14.9 1.6 12 6.1 0.8 3.0 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA RNase_J_C PF17770.1 AMK75937.1 - 0.15 13.2 4.5 32 5.6 0.1 4.9 4 0 0 4 4 4 0 Ribonuclease J C-terminal domain SLATT_6 PF18169.1 AMK75938.1 - 1.5e-79 265.7 3.9 1.8e-79 265.4 3.9 1.0 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 6 SLATT_5 PF18160.1 AMK75938.1 - 4.3e-06 26.2 4.1 6.1e-06 25.7 4.1 1.3 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 AGS_C PF18134.1 AMK75939.1 - 5.9e-48 162.1 1.0 1.3e-47 161.0 0.2 2.0 2 0 0 2 2 2 1 Adenylyl/Guanylyl and SMODS C-terminal sensor domain SMODS PF18144.1 AMK75939.1 - 1.4e-47 161.9 0.5 2.9e-47 160.9 0.5 1.5 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Methylase_S PF01420.19 AMK75940.1 - 2e-33 116.0 3.4 3.4e-24 85.9 0.0 2.4 2 1 0 2 2 2 2 Type I restriction modification DNA specificity domain N6_Mtase PF02384.16 AMK75941.1 - 2.4e-108 362.1 0.0 4.1e-108 361.3 0.0 1.4 2 0 0 2 2 2 1 N-6 DNA Methylase HsdM_N PF12161.8 AMK75941.1 - 3.4e-28 99.0 0.8 3.4e-28 99.0 0.8 2.1 2 0 0 2 2 2 1 HsdM N-terminal domain UPF0020 PF01170.18 AMK75941.1 - 1.1e-05 25.2 0.1 0.00022 21.0 0.1 2.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Eco57I PF07669.11 AMK75941.1 - 0.00035 21.0 0.0 0.0013 19.2 0.0 2.0 1 1 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 AMK75941.1 - 0.00044 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AMK75941.1 - 0.0058 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Creatinase_N PF01321.18 AMK75941.1 - 0.058 14.0 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Methylase_S PF01420.19 AMK75942.1 - 9.8e-06 25.9 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Type I restriction modification DNA specificity domain SRAP PF02586.14 AMK75943.1 - 4.7e-66 222.5 0.3 5.3e-66 222.3 0.3 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Claudin_2 PF13903.6 AMK75943.1 - 0.043 13.6 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction LdpA_C PF12617.8 AMK75943.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Peptidase_S24 PF00717.23 AMK75944.1 - 1.6e-14 53.6 0.3 2.2e-14 53.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase S24-like IMS PF00817.20 AMK75945.1 - 2.9e-15 56.6 0.0 3.1e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 impB/mucB/samB family Phage_integrase PF00589.22 AMK75946.1 - 3.7e-30 105.0 0.3 6.2e-30 104.2 0.3 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AMK75946.1 - 0.0012 19.1 0.2 1.3 9.4 0.0 2.7 1 1 1 2 2 2 2 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AMK75946.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ribonuc_red_lgC PF02867.15 AMK75946.1 - 0.055 12.0 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain HycA_repressor PF11046.8 AMK75946.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Phage_integrase PF00589.22 AMK75947.1 - 5.1e-07 29.6 0.0 8.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family BrnT_toxin PF04365.13 AMK75948.1 - 1.4e-21 76.6 0.2 1.6e-21 76.4 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system CopG_antitoxin PF12441.8 AMK75949.1 - 2.8e-35 120.7 0.3 3.2e-35 120.5 0.3 1.0 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system DUF4113 PF13438.6 AMK75950.1 - 1.4e-19 69.9 0.2 4.4e-19 68.3 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IMS_C PF11799.8 AMK75950.1 - 3.5e-15 56.7 0.0 8.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 AMK75950.1 - 1.8e-09 37.7 0.0 5.7e-09 36.1 0.0 1.8 2 1 0 2 2 2 1 impB/mucB/samB family Bac_DNA_binding PF00216.21 AMK75951.1 - 1.9e-27 95.3 0.0 2.1e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AMK75951.1 - 1.5e-08 34.8 0.0 1.6e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 AMK75951.1 - 0.0059 16.7 0.0 0.0069 16.5 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_1 PF18174.1 AMK75951.1 - 0.033 14.0 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 TetR_C_30 PF17939.1 AMK75951.1 - 0.072 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HU-CCDC81_bac_2 PF18175.1 AMK75951.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 NTP_transf_2 PF01909.23 AMK75954.1 - 0.00097 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AMK75954.1 - 0.0015 18.6 0.1 0.006 16.6 0.1 2.0 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Pentapeptide PF00805.22 AMK75955.1 - 3.1e-10 39.5 2.6 2.3e-06 27.1 2.4 2.3 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AMK75955.1 - 5e-10 39.4 8.4 2.2e-09 37.4 8.3 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AMK75955.1 - 2.7e-09 37.0 9.9 1.4e-05 25.1 7.5 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) aGPT-Pplase2 PF18724.1 AMK75955.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 YccF PF03733.13 AMK75957.1 - 2.6e-30 104.9 35.0 8.9e-17 61.5 8.6 2.1 2 0 0 2 2 2 2 Inner membrane component domain DUF3930 PF13067.6 AMK75957.1 - 0.0019 18.4 8.1 0.04 14.2 1.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3930) NYN PF01936.18 AMK75958.1 - 2.2e-26 93.1 0.1 6.4e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 NYN domain OST-HTH PF12872.7 AMK75958.1 - 9.4e-08 31.8 0.0 2.7e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PIN_11 PF18479.1 AMK75958.1 - 0.0051 17.0 0.2 0.021 15.0 0.0 2.1 2 1 1 3 3 3 1 PIN like domain PIN7 PF18475.1 AMK75958.1 - 0.037 14.7 0.1 0.18 12.5 0.0 2.3 2 1 0 2 2 2 0 PIN domain Histone_HNS PF00816.21 AMK75959.1 - 2.5e-23 82.7 1.1 2.8e-23 82.5 1.1 1.0 1 0 0 1 1 1 1 H-NS histone family Chordopox_A30L PF06015.12 AMK75959.1 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus A30L protein BCL9 PF11502.8 AMK75961.1 - 0.23 11.3 0.9 0.5 10.2 0.9 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein UvrD-helicase PF00580.21 AMK75962.1 - 3.3e-40 138.5 2.6 1.3e-20 74.2 0.6 2.8 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AMK75962.1 - 3.5e-24 85.8 0.4 3.8e-23 82.4 0.1 2.7 3 1 0 3 3 3 1 AAA domain UvrD_C PF13361.6 AMK75962.1 - 2.7e-18 66.5 0.1 7.7e-17 61.7 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AMK75962.1 - 5.5e-09 36.0 0.1 1e-06 28.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 AMK75962.1 - 2e-08 34.3 0.0 5.5e-07 29.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 AMK75962.1 - 1.8e-07 31.1 0.1 0.0097 15.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 AMK75962.1 - 6.4e-06 25.9 2.2 4e-05 23.3 0.6 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 AMK75962.1 - 0.0079 15.7 0.0 5.1 6.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 AMK75962.1 - 0.011 16.0 5.8 0.026 14.8 0.6 3.6 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 AMK75962.1 - 0.035 14.1 0.1 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Catalase-rel PF06628.12 AMK75962.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Catalase-related immune-responsive DUF2075 PF09848.9 AMK75962.1 - 0.17 11.1 3.8 2.9 7.0 0.8 3.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_6 PF12774.7 AMK75962.1 - 0.47 9.4 3.4 0.24 10.3 0.4 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region zf-ribbon_3 PF13248.6 AMK75963.1 - 0.013 14.9 0.4 0.021 14.2 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain SusD-like_2 PF12771.7 AMK75963.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane zinc_ribbon_2 PF13240.6 AMK75963.1 - 0.12 12.1 1.2 0.39 10.5 1.1 1.8 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AMK75963.1 - 0.2 11.6 2.3 0.8 9.7 0.6 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF927 PF06048.11 AMK75964.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF927) Response_reg PF00072.24 AMK75966.1 - 4.1e-32 110.7 0.0 1e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Hemerythrin PF01814.23 AMK75967.1 - 2.8e-09 37.7 3.7 3.2e-09 37.5 3.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain H_PPase PF03030.16 AMK75967.1 - 0.091 11.4 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase TPR_2 PF07719.17 AMK75968.1 - 0.00073 19.5 2.2 0.47 10.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75968.1 - 0.0098 16.2 0.3 1.4 9.3 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 AMK75968.1 - 0.017 15.1 0.1 0.4 10.8 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 AMK75968.1 - 0.02 14.3 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_11 PF13414.6 AMK75968.1 - 0.022 14.4 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 AMK75968.1 - 0.037 13.9 0.0 7.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK75968.1 - 0.14 12.1 0.5 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Cupin_7 PF12973.7 AMK75969.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain PAS_3 PF08447.12 AMK75969.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 PAS fold AflR PF08493.10 AMK75973.1 - 8.8 5.7 13.6 10 5.5 13.6 1.4 1 1 0 1 1 1 0 Aflatoxin regulatory protein RadC PF04002.15 AMK75974.1 - 9.5e-44 148.3 0.0 1.3e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AMK75974.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2922 PF11148.8 AMK75974.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Phage_integrase PF00589.22 AMK75976.1 - 1.2e-28 100.0 0.0 1.9e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AMK75976.1 - 0.0068 16.7 0.5 0.12 12.7 0.0 2.8 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain DUF2087 PF09860.9 AMK75976.1 - 0.057 13.6 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Phage_integrase PF00589.22 AMK75978.1 - 6.1e-27 94.5 0.2 1.4e-26 93.3 0.1 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AMK75978.1 - 0.0019 18.5 0.3 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain SIR2 PF02146.17 AMK75979.1 - 6.1e-55 185.9 0.0 7.5e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 AMK75979.1 - 3.2e-07 30.1 0.0 9.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain FYVE_2 PF02318.16 AMK75979.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger CpXC PF14353.6 AMK75979.1 - 0.63 10.1 2.0 22 5.1 0.1 3.0 1 1 2 3 3 3 0 CpXC protein DASH_Duo1 PF08651.10 AMK75980.1 - 0.013 15.2 1.9 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 TFR_dimer PF04253.15 AMK75980.1 - 0.037 14.1 0.6 0.059 13.5 0.6 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain End3 PF12761.7 AMK75980.1 - 0.048 13.8 1.9 0.079 13.1 1.9 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF2802 PF10975.8 AMK75980.1 - 0.07 13.3 3.8 5.3 7.2 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Med29 PF11568.8 AMK75980.1 - 0.071 13.3 0.3 0.15 12.3 0.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 29 TSC22 PF01166.18 AMK75980.1 - 0.077 13.3 0.4 0.2 12.0 0.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 AMK75980.1 - 0.11 12.4 6.1 2.8 7.9 0.0 2.9 2 2 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MscS_porin PF12795.7 AMK75980.1 - 0.12 11.9 5.7 0.19 11.2 5.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain SlyX PF04102.12 AMK75980.1 - 0.36 11.5 3.9 0.31 11.7 1.1 2.1 2 0 0 2 2 2 0 SlyX FapA PF03961.13 AMK75980.1 - 0.36 9.4 1.5 0.44 9.1 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 AMK75980.1 - 0.39 11.0 5.2 1.6 9.0 5.2 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 AMK75980.1 - 0.4 10.7 4.5 0.6 10.1 4.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF697 PF05128.12 AMK75981.1 - 5.4e-10 39.2 2.1 8.1e-09 35.4 2.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF697) MMR_HSR1 PF01926.23 AMK75981.1 - 4.8e-07 29.9 0.0 8.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EcsC PF12787.7 AMK75981.1 - 0.039 13.6 0.2 0.092 12.4 0.0 1.7 2 0 0 2 2 2 0 EcsC protein family RsgA_GTPase PF03193.16 AMK75981.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 AMK75981.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 AMK75981.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 AMK75982.1 - 7.1e-13 48.6 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AMK75982.1 - 2.6e-06 27.6 0.0 0.11 12.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 AMK75982.1 - 7.4e-05 22.7 0.4 0.0072 16.2 0.1 3.2 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 AMK75982.1 - 0.00027 20.5 0.0 0.19 11.2 0.0 2.5 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain Septin PF00735.18 AMK75982.1 - 0.0016 17.8 0.0 0.0048 16.2 0.0 1.8 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 AMK75982.1 - 0.0026 18.2 0.2 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF4131 PF13567.6 AMK75982.1 - 0.004 16.8 5.5 0.0065 16.1 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) FeoB_N PF02421.18 AMK75982.1 - 0.006 16.1 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 AMK75982.1 - 0.008 15.6 0.0 0.1 12.0 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 AMK75982.1 - 0.0095 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 AMK75982.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 AMK75982.1 - 0.037 13.1 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 AMK75982.1 - 0.04 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 AMK75982.1 - 0.054 13.3 0.0 1.3 8.7 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 AMK75982.1 - 0.065 12.5 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 AMK75982.1 - 0.092 13.3 0.0 0.84 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter G-alpha PF00503.20 AMK75982.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Response_reg PF00072.24 AMK75985.1 - 6.5e-21 74.6 0.4 9.9e-21 74.0 0.4 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AMK75985.1 - 1.8e-11 43.6 0.9 3.8e-11 42.6 0.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 AMK75985.1 - 2e-06 27.5 0.5 4.3e-06 26.4 0.5 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 AMK75985.1 - 0.0091 16.1 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HOIP-UBA PF16678.5 AMK75985.1 - 0.013 15.5 0.4 3.2 7.7 0.2 2.8 2 1 1 3 3 3 0 HOIP UBA domain pair HTH_29 PF13551.6 AMK75985.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix RACo_linker PF17650.1 AMK75985.1 - 0.058 13.3 0.0 0.85 9.5 0.0 2.4 2 1 0 2 2 2 0 RACo linker region HTH_23 PF13384.6 AMK75985.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HATPase_c PF02518.26 AMK75986.1 - 9.3e-12 45.4 0.0 1.7e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK75986.1 - 0.00015 21.7 0.0 0.0009 19.2 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AMK75986.1 - 0.0073 16.3 0.0 0.037 14.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AMK75986.1 - 0.06 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GHKL domain CTP_transf_1 PF01148.20 AMK75986.1 - 2.8 7.6 11.3 4.3 7.0 11.3 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family HKR_ArcB_TM PF18415.1 AMK75987.1 - 0.02 15.7 0.6 0.034 14.9 0.6 1.5 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain DPM2 PF07297.12 AMK75987.1 - 0.068 13.5 2.5 0.096 13.0 2.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PEP-CTERM PF07589.11 AMK75988.1 - 0.025 14.6 1.0 0.07 13.2 1.0 1.8 1 0 0 1 1 1 0 PEP-CTERM motif Cu_bind_CorA PF18252.1 AMK75989.1 - 0.024 14.3 0.3 0.047 13.3 0.3 1.5 1 0 0 1 1 1 0 Copper(I)-binding protein CorA PEP-CTERM PF07589.11 AMK75989.1 - 0.032 14.3 0.8 0.032 14.3 0.8 2.5 2 0 0 2 2 2 0 PEP-CTERM motif Sulfotransfer_3 PF13469.6 AMK75990.1 - 3.6e-23 83.1 0.5 1.8e-22 80.8 0.0 2.4 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 AMK75990.1 - 6.8e-12 45.4 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain SEC-C PF02810.15 AMK75990.1 - 4.2e-10 39.3 10.8 8.4e-10 38.4 10.8 1.5 1 0 0 1 1 1 1 SEC-C motif TPR_17 PF13431.6 AMK75990.1 - 3.2e-08 33.4 8.9 0.24 11.8 0.1 5.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK75990.1 - 2.4e-07 31.3 13.7 0.0059 17.2 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AMK75990.1 - 2.4e-06 27.2 17.5 0.011 15.8 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 AMK75990.1 - 2.9e-06 27.7 13.0 0.0024 18.4 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 AMK75990.1 - 4.1e-06 27.0 15.3 0.086 13.1 0.1 4.6 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 AMK75990.1 - 2.3e-05 24.0 1.0 1.3 8.8 0.1 4.2 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 AMK75990.1 - 2.5e-05 24.7 15.3 0.082 13.8 0.0 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 AMK75990.1 - 3e-05 23.7 15.2 0.0028 17.4 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TAF1_subA PF14929.6 AMK75990.1 - 9.8e-05 21.9 1.1 0.00014 21.4 1.1 1.1 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_8 PF13181.6 AMK75990.1 - 0.0005 20.1 0.8 9 6.8 0.4 4.4 6 0 0 6 6 3 2 Tetratricopeptide repeat zf-UBP_var PF17807.1 AMK75990.1 - 0.00074 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Variant UBP zinc finger TPR_9 PF13371.6 AMK75990.1 - 0.00084 19.4 10.0 0.0028 17.8 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK75990.1 - 0.0021 18.3 0.3 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DNA_topoisoIV PF00521.20 AMK75990.1 - 0.082 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A TPR_10 PF13374.6 AMK75990.1 - 0.11 12.4 19.9 0.2 11.6 0.0 5.5 4 1 0 5 5 5 0 Tetratricopeptide repeat AAA_25 PF13481.6 AMK75991.1 - 6.9e-19 68.2 0.0 3.5e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 AMK75991.1 - 2e-18 66.6 0.2 4.4e-11 42.6 0.1 2.2 1 1 1 2 2 2 2 KaiC Rubredoxin_2 PF18073.1 AMK75991.1 - 1e-10 41.1 7.6 1.5e-10 40.6 7.6 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 AMK75991.1 - 3.7e-09 36.5 0.0 7.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Rad51 PF08423.11 AMK75991.1 - 5.3e-09 35.7 1.1 3.3e-07 29.8 1.1 2.6 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 AMK75991.1 - 1.3e-08 34.5 0.3 2.7e-06 26.9 0.1 2.2 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain Lon_C PF05362.13 AMK75991.1 - 2.1e-06 27.5 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain DUF2075 PF09848.9 AMK75991.1 - 2.4e-06 27.0 0.1 3.2e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) GvpD PF07088.11 AMK75991.1 - 4.4e-06 25.6 0.0 0.0058 15.3 0.0 2.9 1 1 1 3 3 3 2 GvpD gas vesicle protein RecA PF00154.21 AMK75991.1 - 1.2e-05 25.0 0.5 1.9e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.29 AMK75991.1 - 7.2e-05 23.2 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AMK75991.1 - 0.00031 20.8 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK75991.1 - 0.00053 20.4 0.4 0.0012 19.2 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AMK75991.1 - 0.00089 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AMK75991.1 - 0.0055 17.0 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AMK75991.1 - 0.011 15.1 0.9 0.026 13.8 0.4 1.7 1 1 1 2 2 2 0 Zeta toxin PAXNEB PF05625.11 AMK75991.1 - 0.011 14.9 0.4 0.017 14.3 0.4 1.2 1 0 0 1 1 1 0 PAXNEB protein AAA_22 PF13401.6 AMK75991.1 - 0.013 15.8 0.2 0.034 14.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AMK75991.1 - 0.022 14.5 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.9 AMK75991.1 - 0.031 13.8 0.2 0.043 13.3 0.2 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_17 PF13207.6 AMK75991.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AMK75991.1 - 0.054 14.0 0.3 0.11 13.0 0.3 1.6 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 AMK75991.1 - 0.054 12.5 0.2 0.093 11.8 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 AMK75991.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 AMK75991.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TK PF00265.18 AMK75991.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase AAA_29 PF13555.6 AMK75991.1 - 1.2 9.0 6.1 0.16 11.7 0.6 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain PLDc_2 PF13091.6 AMK75992.1 - 3.2e-32 111.2 0.0 5e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PP_kinase_C PF13090.6 AMK75992.1 - 2.5e-06 27.1 0.0 0.00055 19.4 0.0 2.2 2 0 0 2 2 2 2 Polyphosphate kinase C-terminal domain 2 PLDc PF00614.22 AMK75992.1 - 9.4e-05 22.4 3.8 0.094 12.9 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif CBM53 PF16760.5 AMK75993.1 - 2.5e-17 63.3 0.5 1.2e-10 41.8 0.0 2.9 3 0 0 3 3 3 2 Starch/carbohydrate-binding module (family 53) CBM_21 PF03370.13 AMK75993.1 - 1.4e-14 54.2 0.0 2e-07 31.2 0.1 2.7 2 1 0 2 2 2 2 Carbohydrate/starch-binding module (family 21) Exo_endo_phos PF03372.23 AMK75993.1 - 2.3e-12 46.9 0.8 5.2e-12 45.8 0.8 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM_25 PF03423.13 AMK75993.1 - 0.0045 17.2 0.4 7.4 6.9 0.0 3.5 3 0 0 3 3 3 2 Carbohydrate binding domain (family 25) Alginate_lyase2 PF08787.11 AMK75993.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Alginate lyase SCPU PF05229.15 AMK75993.1 - 0.21 12.0 0.5 0.52 10.7 0.2 1.7 2 0 0 2 2 2 0 Spore Coat Protein U domain Glyco_hydro_57 PF03065.15 AMK75994.1 - 1.4e-41 142.8 0.0 6e-41 140.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF1957 PF09210.11 AMK75994.1 - 4.4e-34 116.9 0.3 4.4e-34 116.9 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1957) SQHop_cyclase_N PF13249.6 AMK75994.1 - 0.067 12.3 0.1 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain DUF4912 PF16258.5 AMK75995.1 - 6.2e-11 42.5 0.0 9.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4912) Alpha-amylase PF00128.24 AMK75996.1 - 2.3e-20 73.4 0.0 3.1e-14 53.3 0.0 3.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 AMK75996.1 - 2.1e-13 50.4 0.0 7e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glycos_transf_1 PF00534.20 AMK75997.1 - 0.093 12.3 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 Nup88 PF10168.9 AMK75998.1 - 0.01 13.7 0.2 0.012 13.4 0.2 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF5405 PF17399.2 AMK75998.1 - 0.015 15.6 0.1 0.95 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) DUF948 PF06103.11 AMK75998.1 - 0.033 14.4 2.0 1.3 9.3 0.2 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) VWA PF00092.28 AMK75999.1 - 2.5e-13 50.6 0.2 7.9e-13 49.0 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 AMK75999.1 - 1.1e-09 38.4 0.2 3.3e-09 36.9 0.2 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AMK75999.1 - 0.0008 20.0 0.1 0.0038 17.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 AMK75999.1 - 0.0031 17.6 0.2 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 AMK75999.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein PGK PF00162.19 AMK76000.1 - 2.3e-143 477.7 0.2 2.6e-143 477.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HEPN_RiboL-PSP PF18735.1 AMK76004.1 - 0.0046 16.9 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 RiboL-PSP-HEPN ACR_tran PF00873.19 AMK76005.1 - 1.1e-230 768.2 11.4 1.3e-230 768.0 11.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AMK76005.1 - 0.0021 17.5 18.6 0.012 15.0 6.4 2.3 2 0 0 2 2 2 2 Protein export membrane protein HMA PF00403.26 AMK76005.1 - 0.022 15.2 2.1 1.3 9.5 0.3 3.1 3 0 0 3 3 3 0 Heavy-metal-associated domain DuoxA PF10204.9 AMK76005.1 - 0.041 12.9 0.2 0.041 12.9 0.2 2.4 2 0 0 2 2 2 0 Dual oxidase maturation factor FeS_assembly_P PF01883.19 AMK76005.1 - 0.34 11.1 4.6 3.3 8.0 0.0 4.2 5 0 0 5 5 5 0 Iron-sulfur cluster assembly protein GGDEF_2 PF17853.1 AMK76005.1 - 0.46 10.8 5.9 0.31 11.3 0.1 3.5 4 0 0 4 4 4 0 GGDEF-like domain Patched PF02460.18 AMK76005.1 - 3 5.8 6.0 5.3 5.0 6.0 1.3 1 0 0 1 1 1 0 Patched family HlyD_D23 PF16576.5 AMK76006.1 - 4.3e-15 55.5 6.4 2.3e-14 53.1 6.4 1.9 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76006.1 - 2.6e-14 53.8 5.1 4.1e-11 43.5 0.1 3.1 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK76006.1 - 9.2e-05 22.2 1.5 9.2e-05 22.2 1.5 3.3 4 0 0 4 4 4 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76006.1 - 0.014 15.2 0.1 0.53 10.1 0.1 2.8 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AMK76006.1 - 0.028 14.6 0.1 0.44 10.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 TetR_C_32 PF09209.11 AMK76007.1 - 6.5e-21 74.6 0.1 1.1e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AMK76007.1 - 6.8e-13 48.2 0.9 1.3e-12 47.3 0.9 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_30 PF17939.1 AMK76007.1 - 0.00065 19.9 0.3 0.0013 19.0 0.3 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain ECH_1 PF00378.20 AMK76008.1 - 1.7e-16 60.3 0.0 2.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_N PF00551.19 AMK76008.1 - 3.3e-10 40.0 0.0 5.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AMK76008.1 - 6.4e-10 39.2 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DJ-1_PfpI PF01965.24 AMK76009.1 - 3.4e-26 92.0 0.0 4.7e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 AMK76009.1 - 6e-21 74.5 0.2 9.7e-21 73.8 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AMK76009.1 - 1.1e-11 44.6 0.0 2.7e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_C_31 PF17940.1 AMK76009.1 - 0.014 15.6 2.5 0.12 12.6 2.0 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_29 PF13551.6 AMK76009.1 - 0.17 11.9 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AMK76010.1 - 3.9e-16 58.5 2.2 6.5e-16 57.8 1.7 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AMK76010.1 - 7.2e-10 38.2 0.3 1.5e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK76010.1 - 3e-08 33.3 0.1 5.4e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AMK76010.1 - 5.3e-08 33.0 0.2 6.6e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AMK76010.1 - 2.8e-05 23.7 0.2 9.5e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AMK76010.1 - 0.00056 19.3 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_Mga PF08280.11 AMK76010.1 - 0.0024 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_29 PF13551.6 AMK76010.1 - 0.0025 17.8 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_AsnC-type PF13404.6 AMK76010.1 - 0.003 17.3 0.2 0.0081 16.0 0.0 1.8 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AMK76010.1 - 0.0033 17.0 0.0 0.0094 15.5 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GerE PF00196.19 AMK76010.1 - 0.004 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_DeoR PF08220.12 AMK76010.1 - 0.0048 16.6 1.2 0.022 14.5 0.1 2.5 3 0 0 3 3 3 1 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 AMK76010.1 - 0.005 16.9 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AMK76010.1 - 0.006 16.5 1.5 0.046 13.7 0.1 2.9 3 1 0 3 3 3 1 HTH domain HTH_10 PF04967.12 AMK76010.1 - 0.015 15.1 0.2 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain HTH_17 PF12728.7 AMK76010.1 - 0.016 15.4 0.0 0.046 13.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain PCI PF01399.27 AMK76010.1 - 0.021 15.3 2.5 0.18 12.3 0.4 2.3 1 1 1 2 2 2 0 PCI domain HTH_5 PF01022.20 AMK76010.1 - 0.032 14.1 0.3 0.08 12.8 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF1492 PF07374.11 AMK76010.1 - 0.05 13.8 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) HTH_36 PF13730.6 AMK76010.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AMK76010.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 AMK76010.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 1 0 HTH domain HTH_Tnp_1_2 PF13022.6 AMK76010.1 - 0.067 13.3 0.1 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_1 PF00126.27 AMK76010.1 - 0.076 13.0 0.1 0.22 11.5 0.1 1.8 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 AMK76010.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.4 3 0 0 3 3 2 0 Helix-turn-helix domain, rpiR family HTH_31 PF13560.6 AMK76010.1 - 0.2 12.0 1.2 0.37 11.2 1.2 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain DUF4974 PF16344.5 AMK76011.1 - 4.6e-12 45.8 0.0 7.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) DUF4880 PF16220.5 AMK76011.1 - 1.2e-10 41.0 8.7 3.1e-10 39.8 8.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) FecR PF04773.13 AMK76011.1 - 2e-08 34.8 0.3 1.1e-07 32.3 0.3 2.0 1 1 0 1 1 1 1 FecR protein TonB_dep_Rec PF00593.24 AMK76012.1 - 3.2e-30 106.5 46.9 2.4e-28 100.2 46.9 2.1 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK76012.1 - 6.6e-21 74.9 0.4 1.8e-20 73.5 0.4 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AMK76012.1 - 6.3e-11 41.9 2.2 1.2e-09 37.8 0.3 3.4 3 0 0 3 3 3 1 Secretin and TonB N terminus short domain PepSY_TM PF03929.16 AMK76013.1 - 1.4e-64 218.6 4.8 1.7e-64 218.3 4.8 1.1 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AMK76013.1 - 5.2e-09 36.5 0.0 1e-06 29.2 0.0 2.4 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain CopD PF05425.13 AMK76013.1 - 0.013 15.9 7.3 1.3 9.5 0.2 3.2 3 0 0 3 3 3 0 Copper resistance protein D PepSY_TM_like_2 PF16357.5 AMK76013.1 - 0.026 14.5 0.6 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Putative PepSY_TM-like DUF2306 PF10067.9 AMK76013.1 - 0.11 12.6 1.2 1.2 9.3 0.1 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) DUF4405 PF14358.6 AMK76013.1 - 1.6 9.4 13.1 7.3 7.2 0.8 5.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4405) Cation_efflux PF01545.21 AMK76014.1 - 1.8e-31 109.5 10.6 2.3e-31 109.1 10.6 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AMK76014.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter CitMHS PF03600.16 AMK76014.1 - 0.24 10.5 7.4 0.36 10.0 7.4 1.2 1 0 0 1 1 1 0 Citrate transporter MerC PF03203.14 AMK76014.1 - 5.1 7.6 13.7 0.57 10.7 1.7 2.7 1 1 1 2 2 2 0 MerC mercury resistance protein Peptidase_S11 PF00768.20 AMK76015.1 - 7.6e-61 205.6 0.0 9.4e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 AMK76015.1 - 3.1e-09 36.7 0.2 5.3e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family SPOR PF05036.13 AMK76015.1 - 0.00012 22.4 0.3 0.00097 19.5 0.1 2.5 2 1 1 3 3 3 1 Sporulation related domain Beta-lactamase PF00144.24 AMK76015.1 - 0.00077 18.8 0.6 0.014 14.7 0.1 2.3 1 1 0 2 2 2 1 Beta-lactamase Peptidase_S13 PF02113.15 AMK76015.1 - 0.013 14.2 2.1 0.044 12.5 0.1 2.1 1 1 1 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Transpeptidase PF00905.22 AMK76015.1 - 0.059 12.6 0.8 0.53 9.4 0.1 2.1 2 0 0 2 2 2 0 Penicillin binding protein transpeptidase domain Dimer_Tnp_Tn5 PF02281.16 AMK76015.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain SlyX PF04102.12 AMK76016.1 - 2.4e-23 82.5 1.4 2.6e-23 82.4 1.4 1.0 1 0 0 1 1 1 1 SlyX DUF16 PF01519.16 AMK76016.1 - 0.004 17.6 1.7 0.0044 17.5 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF16 Herpes_UL6 PF01763.16 AMK76016.1 - 0.023 13.3 0.2 0.023 13.2 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Laminin_II PF06009.12 AMK76016.1 - 0.037 14.1 0.3 0.04 13.9 0.3 1.1 1 0 0 1 1 1 0 Laminin Domain II CEP209_CC5 PF16574.5 AMK76016.1 - 0.049 13.8 1.0 0.12 12.6 1.0 1.7 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 SKI PF01202.22 AMK76018.1 - 0.022 14.9 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase HTS PF04204.16 AMK76019.1 - 2.4e-89 299.2 0.1 3.3e-89 298.8 0.1 1.2 1 0 0 1 1 1 1 Homoserine O-succinyltransferase GATase PF00117.28 AMK76019.1 - 0.0051 16.6 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MafB19-deam PF14437.6 AMK76020.1 - 2.4e-24 85.6 0.0 2.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AMK76020.1 - 1.7e-21 76.0 0.0 2.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 AMK76020.1 - 0.0022 18.1 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 AMK76020.1 - 0.031 14.3 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 AMK76020.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 AMK76020.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 AMK76020.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Proteasome PF00227.26 AMK76022.1 - 1.9e-24 86.2 0.5 3.3e-24 85.4 0.5 1.4 1 1 0 1 1 1 1 Proteasome subunit AAA_2 PF07724.14 AMK76023.1 - 8.1e-53 179.0 0.7 3.5e-41 141.1 0.3 3.2 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 AMK76023.1 - 5.2e-17 62.5 0.4 5.1e-07 30.2 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK76023.1 - 1.2e-07 31.8 0.1 2.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AMK76023.1 - 6.9e-07 29.6 0.0 0.00018 21.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.9 AMK76023.1 - 2.7e-06 27.4 0.1 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 AMK76023.1 - 8e-05 21.8 0.1 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 AMK76023.1 - 0.00013 22.4 3.4 0.00051 20.5 1.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AMK76023.1 - 0.00019 20.9 0.2 0.0054 16.1 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AMK76023.1 - 0.00019 21.2 0.3 0.06 13.1 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 AMK76023.1 - 0.0007 19.3 0.0 0.034 13.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 AMK76023.1 - 0.0012 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AMK76023.1 - 0.0016 19.0 0.0 0.0054 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AMK76023.1 - 0.0095 16.1 0.1 0.025 14.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 AMK76023.1 - 0.012 15.1 0.1 0.043 13.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 AMK76023.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AMK76023.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 AMK76023.1 - 0.034 14.4 0.2 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 AMK76023.1 - 0.045 13.7 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 AMK76023.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AMK76023.1 - 0.05 14.1 0.1 0.21 12.1 0.1 2.0 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 AMK76023.1 - 0.055 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 AMK76023.1 - 0.067 13.6 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 AMK76023.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 AMK76023.1 - 0.17 11.6 0.8 0.76 9.5 0.8 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF971 PF06155.12 AMK76024.1 - 5.4e-28 97.5 0.0 6.7e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF2442 PF10387.9 AMK76024.1 - 0.035 14.4 0.0 3.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2442) Ubie_methyltran PF01209.18 AMK76025.1 - 1.2e-93 312.8 0.1 1.3e-93 312.6 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 AMK76025.1 - 2.6e-21 76.1 0.0 5.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK76025.1 - 1.5e-19 70.4 0.0 2.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK76025.1 - 2.9e-18 66.1 0.0 4.3e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK76025.1 - 4.7e-15 55.8 0.0 6.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76025.1 - 2.2e-11 44.4 0.0 4.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AMK76025.1 - 0.00077 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 AMK76025.1 - 0.00089 18.6 0.0 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 AMK76025.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AMK76025.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 AMK76025.1 - 0.0086 16.2 0.0 0.034 14.3 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 AMK76025.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase UPF0020 PF01170.18 AMK76025.1 - 0.021 14.5 0.1 0.36 10.5 0.0 2.5 2 1 1 3 3 3 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 AMK76025.1 - 0.031 13.4 0.0 0.099 11.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase SCP2 PF02036.17 AMK76026.1 - 1.2e-15 57.8 0.0 2.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family ABC1 PF03109.16 AMK76027.1 - 9.7e-38 129.0 0.1 2.2e-37 127.9 0.1 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 AMK76027.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein kinase domain Porin_2 PF02530.14 AMK76028.1 - 2.3e-11 43.6 12.9 2.5e-10 40.2 12.9 2.1 1 1 0 1 1 1 1 Porin subfamily CENP-F_N PF10481.9 AMK76028.1 - 0.00031 20.5 3.5 0.00046 19.9 3.5 1.1 1 0 0 1 1 1 1 Cenp-F N-terminal domain CASP_C PF08172.12 AMK76028.1 - 0.002 17.5 0.4 0.0046 16.3 0.4 1.6 2 0 0 2 2 2 1 CASP C terminal T2SSM PF04612.12 AMK76028.1 - 0.0032 17.6 3.0 0.008 16.2 3.0 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF560 PF04575.13 AMK76028.1 - 0.0073 15.8 0.4 0.015 14.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF560) P4Ha_N PF08336.11 AMK76028.1 - 0.0082 16.2 0.1 0.19 11.8 1.6 2.1 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4533 PF15047.6 AMK76028.1 - 0.011 15.3 0.3 0.017 14.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) HR1 PF02185.16 AMK76028.1 - 0.021 14.9 5.1 0.037 14.2 5.1 1.4 1 0 0 1 1 1 0 Hr1 repeat Herpes_UL6 PF01763.16 AMK76028.1 - 0.022 13.3 1.3 0.032 12.8 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DASH_Spc19 PF08287.11 AMK76028.1 - 0.027 14.4 3.1 0.043 13.7 3.1 1.2 1 0 0 1 1 1 0 Spc19 Cep57_MT_bd PF06657.13 AMK76028.1 - 0.035 14.6 2.6 0.071 13.6 2.6 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4600 PF15372.6 AMK76028.1 - 0.041 14.3 0.5 0.068 13.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) SKA1 PF07160.12 AMK76028.1 - 0.063 13.1 1.9 0.094 12.5 1.9 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 BRE1 PF08647.11 AMK76028.1 - 0.064 13.3 3.7 0.1 12.7 3.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase PspA_IM30 PF04012.12 AMK76028.1 - 0.11 12.1 6.8 0.17 11.5 6.8 1.2 1 0 0 1 1 1 0 PspA/IM30 family FapA PF03961.13 AMK76028.1 - 0.11 11.1 0.4 0.16 10.6 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HMMR_N PF15905.5 AMK76028.1 - 0.13 11.8 3.6 0.17 11.3 3.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 AMK76028.1 - 0.13 12.5 3.5 0.2 11.9 3.5 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF3251 PF11622.8 AMK76028.1 - 0.16 11.6 2.9 4.8 6.8 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) SlyX PF04102.12 AMK76028.1 - 0.24 12.1 4.4 0.49 11.1 4.4 1.5 1 0 0 1 1 1 0 SlyX ADIP PF11559.8 AMK76028.1 - 0.55 10.3 6.4 0.86 9.7 6.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 AMK76028.1 - 1.2 9.6 6.1 0.5 10.8 2.9 2.0 2 0 0 2 2 1 0 Lipoprotein leucine-zipper DivIC PF04977.15 AMK76028.1 - 1.6 8.5 3.8 3.1 7.6 3.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Cytochrom_C_2 PF01322.20 AMK76029.1 - 4.3e-06 27.6 0.9 8.5e-06 26.7 0.2 1.7 2 0 0 2 2 2 1 Cytochrome C' Cytochrom_B562 PF07361.11 AMK76029.1 - 0.01 16.5 0.1 0.015 15.9 0.1 1.4 1 1 0 1 1 1 0 Cytochrome b562 LemA PF04011.12 AMK76029.1 - 0.035 14.0 0.1 0.062 13.2 0.1 1.5 1 1 0 1 1 1 0 LemA family GED PF02212.18 AMK76029.1 - 0.13 12.4 2.2 0.49 10.6 0.2 2.1 1 1 1 2 2 2 0 Dynamin GTPase effector domain LMBR1 PF04791.16 AMK76029.1 - 0.25 10.2 0.2 0.3 9.9 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GlnE PF03710.15 AMK76030.1 - 1.5e-162 538.8 0.0 5.5e-81 271.7 0.0 2.4 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 AMK76030.1 - 1e-50 171.6 11.0 7e-40 136.5 3.3 2.8 3 0 0 3 3 3 2 GlnD PII-uridylyltransferase HALZ PF02183.18 AMK76030.1 - 0.00022 21.4 0.2 0.0018 18.5 0.0 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF294 PF03445.13 AMK76030.1 - 0.012 15.4 0.0 0.51 10.1 0.0 2.6 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 Ribonuclease_T2 PF00445.18 AMK76031.1 - 6e-16 59.2 0.3 9.9e-16 58.5 0.3 1.4 1 1 0 1 1 1 1 Ribonuclease T2 family PLDc_2 PF13091.6 AMK76032.1 - 3e-23 82.2 0.0 2.1e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain HlyD_D23 PF16576.5 AMK76034.1 - 8.8e-18 64.3 10.2 2.1e-17 63.1 10.2 1.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76034.1 - 2.8e-16 60.1 8.7 8.3e-11 42.5 0.1 3.0 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK76034.1 - 9.3e-08 31.8 4.2 9.3e-08 31.8 4.2 3.0 3 1 0 3 3 3 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76034.1 - 5.5e-05 22.9 0.4 0.00098 18.9 0.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 AMK76034.1 - 0.0052 17.0 0.1 0.98 9.7 0.1 2.5 2 0 0 2 2 2 1 Peptidase family M23 TPR_MLP1_2 PF07926.12 AMK76034.1 - 0.01 15.9 6.0 0.023 14.8 6.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein RnfC_N PF13375.6 AMK76034.1 - 0.018 15.0 0.6 0.089 12.8 0.3 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF4131 PF13567.6 AMK76034.1 - 0.018 14.7 2.3 0.044 13.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF4407 PF14362.6 AMK76034.1 - 0.022 14.1 8.7 0.04 13.3 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 AMK76034.1 - 0.028 13.0 3.2 0.041 12.5 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HemX PF04375.14 AMK76034.1 - 0.044 13.1 0.1 0.044 13.1 0.1 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1664 PF07889.12 AMK76034.1 - 0.081 13.0 1.9 0.14 12.2 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PYNP_C PF07831.13 AMK76034.1 - 0.09 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain MacB_PCD PF12704.7 AMK76035.1 - 1.4e-38 133.3 4.5 1.4e-38 133.3 4.5 2.3 2 0 0 2 2 2 1 MacB-like periplasmic core domain ABC_tran PF00005.27 AMK76035.1 - 2.1e-31 109.3 0.0 3.3e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter FtsX PF02687.21 AMK76035.1 - 1.6e-11 44.5 8.9 1.8e-11 44.4 0.2 3.1 3 0 0 3 3 3 1 FtsX-like permease family SMC_N PF02463.19 AMK76035.1 - 1.8e-07 30.9 0.1 0.00094 18.7 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK76035.1 - 9.6e-06 25.6 0.1 0.086 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK76035.1 - 0.00059 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4064 PF13273.6 AMK76035.1 - 0.00079 19.7 6.9 0.026 14.8 4.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) RsgA_GTPase PF03193.16 AMK76035.1 - 0.00098 19.1 0.2 0.0038 17.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 AMK76035.1 - 0.0096 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AMK76035.1 - 0.027 14.8 0.3 0.13 12.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AMK76035.1 - 0.04 14.3 1.1 0.11 12.9 0.4 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 AMK76035.1 - 0.054 14.0 0.0 0.097 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 AMK76035.1 - 0.055 12.8 0.2 8 5.7 0.0 2.5 2 0 0 2 2 2 0 KaiC DUF87 PF01935.17 AMK76035.1 - 0.079 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain G-alpha PF00503.20 AMK76035.1 - 0.29 10.3 0.0 0.69 9.0 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit HRG PF16954.5 AMK76035.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.5 3 0 0 3 3 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene OEP PF02321.18 AMK76036.1 - 4.1e-43 147.4 46.2 4.2e-22 78.9 17.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein TBCA PF02970.16 AMK76036.1 - 0.099 13.0 0.7 0.62 10.4 0.0 2.4 3 0 0 3 3 3 0 Tubulin binding cofactor A Unstab_antitox PF09720.10 AMK76038.1 - 1.4e-13 50.6 3.6 1.9e-13 50.2 3.6 1.2 1 0 0 1 1 1 1 Putative addiction module component UDG PF03167.19 AMK76039.1 - 2.2e-32 112.2 0.0 2.6e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Exo_endo_phos PF03372.23 AMK76040.1 - 2.2e-26 92.8 0.2 2.5e-26 92.7 0.2 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AMK76040.1 - 7.6e-06 25.8 0.0 4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase AA_permease_2 PF13520.6 AMK76041.1 - 6.4e-55 186.7 42.0 8e-55 186.4 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AMK76041.1 - 2e-41 142.1 39.2 2.5e-41 141.8 39.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 AMK76041.1 - 1.9e-05 24.7 3.9 1.9e-05 24.7 3.9 4.6 6 0 0 6 6 6 1 C-terminus of AA_permease B277 PF17623.2 AMK76041.1 - 2.4 7.1 5.2 1.6 7.7 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function Redoxin PF08534.10 AMK76042.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 AMK76042.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TonB_dep_Rec PF00593.24 AMK76043.1 - 1.2e-45 157.3 43.8 1.2e-45 157.3 43.8 2.1 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK76043.1 - 1.1e-16 61.3 0.9 3.4e-16 59.8 0.2 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain NifQ PF04891.12 AMK76044.1 - 3.7e-55 186.7 0.0 6.7e-55 185.8 0.0 1.4 1 1 0 1 1 1 1 NifQ LPD38 PF18857.1 AMK76044.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 zf-CCCH_2 PF14608.6 AMK76044.1 - 4.2 8.0 6.0 0.59 10.7 1.0 2.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Fer2 PF00111.27 AMK76045.1 - 9.7e-14 51.1 0.4 1.6e-13 50.4 0.4 1.3 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HypD PF01924.16 AMK76045.1 - 0.00043 19.5 0.1 0.00047 19.3 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase formation hypA family Fer2 PF00111.27 AMK76046.1 - 3e-14 52.7 0.2 3.4e-14 52.6 0.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 AMK76046.1 - 0.3 11.2 2.0 1.2 9.2 2.0 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AMK76046.1 - 0.52 10.3 2.8 1.7 8.7 2.8 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Flavodoxin_1 PF00258.25 AMK76047.1 - 1.1e-10 41.8 0.0 2.4e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin Lactamase_B PF00753.27 AMK76047.1 - 1.9e-10 41.1 0.0 2.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK76047.1 - 5e-06 26.2 0.0 8.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FMN_red PF03358.15 AMK76047.1 - 0.0052 16.5 0.0 0.038 13.7 0.0 2.2 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_3 PF12641.7 AMK76047.1 - 0.0099 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 AMK76047.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain ArsC PF03960.15 AMK76048.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 ArsC family Fer4_7 PF12838.7 AMK76049.1 - 5.6e-08 33.3 10.0 7.9e-08 32.8 10.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK76049.1 - 1.5e-06 28.3 9.4 1.9e-06 27.9 9.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AMK76049.1 - 3.4e-06 26.6 13.8 0.00017 21.2 3.0 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AMK76049.1 - 3.5e-06 27.0 10.2 4.8e-06 26.6 10.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK76049.1 - 1.3e-05 25.4 8.1 0.023 15.2 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AMK76049.1 - 6e-05 23.1 9.9 0.00012 22.2 9.9 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK76049.1 - 0.00014 21.8 10.8 0.047 13.8 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AMK76049.1 - 0.00017 21.5 15.5 0.052 13.6 3.5 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AMK76049.1 - 0.00038 21.2 13.9 0.063 14.2 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AMK76049.1 - 0.033 15.1 12.4 0.063 14.2 6.2 2.4 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_11 PF13247.6 AMK76049.1 - 0.11 12.7 6.1 0.19 11.8 6.1 1.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK76049.1 - 0.5 11.0 12.8 0.41 11.2 3.8 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK76049.1 - 1.1 9.8 13.5 0.34 11.4 3.2 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Radical_SAM PF04055.21 AMK76050.1 - 1.1e-27 97.5 0.0 3.4e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Nitro_FeMo-Co PF02579.17 AMK76050.1 - 6.6e-19 68.0 0.0 1.8e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Fer4_14 PF13394.6 AMK76050.1 - 0.00031 20.8 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK76050.1 - 0.0017 18.6 0.0 0.0041 17.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain ABC2_membrane_3 PF12698.7 AMK76051.1 - 3.1e-37 128.5 2.2 3.7e-37 128.2 2.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AMK76051.1 - 1e-26 93.7 15.4 2.9e-25 88.9 11.7 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AMK76051.1 - 8.6e-23 81.0 4.7 1.1e-22 80.7 4.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AMK76051.1 - 8.1e-05 22.6 8.4 8.1e-05 22.6 8.4 1.9 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AMK76052.1 - 1e-45 156.4 11.4 1.1e-45 156.2 11.4 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AMK76052.1 - 1.4e-35 123.0 13.6 1.7e-35 122.7 13.6 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AMK76052.1 - 5.6e-21 74.9 30.7 3.4e-19 69.1 19.6 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC2_membrane_4 PF12730.7 AMK76052.1 - 1.5e-05 25.1 10.1 1.5e-05 25.1 10.1 2.8 2 1 1 3 3 3 1 ABC-2 family transporter protein ABC_tran PF00005.27 AMK76053.1 - 4.5e-57 192.4 0.0 1.2e-27 97.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AMK76053.1 - 1.5e-23 84.1 8.9 3e-09 37.1 0.1 4.1 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK76053.1 - 1.7e-08 35.3 0.0 0.00052 20.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AMK76053.1 - 1.9e-06 27.5 1.7 0.011 15.5 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 AMK76053.1 - 3.8e-06 26.8 2.4 0.015 15.0 0.1 2.8 3 1 0 3 3 2 2 AAA domain SRP54 PF00448.22 AMK76053.1 - 8.4e-06 25.5 0.5 0.028 14.1 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain MukB PF04310.12 AMK76053.1 - 0.00013 21.9 0.4 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 MukB N-terminal AAA_22 PF13401.6 AMK76053.1 - 0.00029 21.1 2.2 0.1 12.9 0.2 3.5 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK76053.1 - 0.00057 20.3 0.1 0.11 12.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AMK76053.1 - 0.00073 19.0 0.1 16 4.9 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 AMK76053.1 - 0.0012 19.2 0.2 2.9 8.3 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 AMK76053.1 - 0.0015 18.6 0.4 0.58 10.2 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 AMK76053.1 - 0.0018 18.0 0.0 1.2 8.7 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 AMK76053.1 - 0.0019 18.3 0.3 1.1 9.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AMK76053.1 - 0.0022 18.2 0.0 3.6 7.9 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AMK76053.1 - 0.0026 17.7 0.2 0.34 10.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_27 PF13514.6 AMK76053.1 - 0.0097 15.5 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 AMK76053.1 - 0.016 14.8 0.5 0.41 10.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain Cdc6_C PF09079.11 AMK76053.1 - 0.02 14.8 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain AAA_19 PF13245.6 AMK76053.1 - 0.03 14.6 0.0 5.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AMK76053.1 - 0.034 13.7 2.2 0.66 9.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 AMK76053.1 - 0.045 13.1 0.8 9.1 5.6 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF3584 PF12128.8 AMK76053.1 - 0.053 11.1 1.7 2.7 5.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_24 PF13479.6 AMK76053.1 - 0.053 13.2 0.9 3.2 7.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 AMK76053.1 - 0.06 13.9 0.5 6.3 7.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK76053.1 - 0.064 13.2 3.6 3.2 7.7 0.1 3.8 5 0 0 5 5 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 AMK76053.1 - 0.069 12.4 0.5 7.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 AMK76053.1 - 0.1 13.0 0.1 19 5.7 0.0 3.2 2 1 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 AMK76053.1 - 0.1 12.5 0.0 16 5.4 0.0 2.5 3 0 0 3 3 2 0 NTPase AAA_14 PF13173.6 AMK76053.1 - 0.12 12.4 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 AMK76053.1 - 0.12 12.0 0.1 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase MMR_HSR1 PF01926.23 AMK76053.1 - 0.17 12.0 0.4 21 5.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 AMK76053.1 - 0.23 11.4 0.0 21 4.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 AMK76053.1 - 0.31 10.9 1.7 5.6 6.8 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 AMK76053.1 - 0.37 11.0 4.5 14 5.9 0.1 3.1 4 0 0 4 4 2 0 AAA domain DUF2813 PF11398.8 AMK76053.1 - 1.2 8.3 3.0 62 2.7 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2813) HlyD_D23 PF16576.5 AMK76054.1 - 1.6e-17 63.4 3.8 2.3e-15 56.4 3.8 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76054.1 - 2e-16 60.6 0.2 1.2e-13 51.6 0.0 2.9 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.20 AMK76054.1 - 5.6e-05 22.9 0.2 0.00043 20.1 0.1 2.2 1 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AMK76054.1 - 0.00033 20.4 0.9 0.00033 20.4 0.9 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76054.1 - 0.0061 16.4 0.1 1.1 9.2 0.0 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme SpoU_sub_bind PF08032.12 AMK76054.1 - 0.097 13.0 0.3 0.26 11.6 0.3 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Peptidase_M23 PF01551.22 AMK76054.1 - 0.21 11.9 0.3 5.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Peptidase family M23 OEP PF02321.18 AMK76054.1 - 2.5 7.9 25.4 0.069 12.9 7.4 3.0 3 0 0 3 3 3 0 Outer membrane efflux protein Proteasome PF00227.26 AMK76055.1 - 0.00011 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Acyltransferase PF01553.21 AMK76056.1 - 4.3e-13 49.0 0.0 6.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF2768 PF10966.8 AMK76056.1 - 0.11 12.9 0.6 0.26 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) PP-binding PF00550.25 AMK76057.1 - 2.5e-09 37.3 0.9 3e-09 37.1 0.9 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site GGDEF PF00990.21 AMK76058.1 - 6.6e-47 159.2 0.6 3.1e-46 157.1 0.0 2.3 2 1 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PocR PF10114.9 AMK76058.1 - 4e-44 150.3 0.2 7.6e-44 149.3 0.2 1.5 1 0 0 1 1 1 1 Sensory domain found in PocR PAS_9 PF13426.7 AMK76058.1 - 1.6e-15 57.2 0.0 1.4e-09 38.2 0.0 3.1 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 AMK76058.1 - 3.4e-12 46.3 0.0 1e-07 31.9 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AMK76058.1 - 1.2e-11 44.9 0.0 6.1e-06 26.5 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AMK76058.1 - 2.7e-09 36.8 0.0 0.00087 19.3 0.0 3.2 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AMK76058.1 - 0.00028 21.1 0.1 0.00096 19.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 AMK76058.1 - 0.0046 17.1 0.3 1.3 9.2 0.0 3.6 4 0 0 4 4 4 1 PAS fold GCN5L1 PF06320.13 AMK76058.1 - 0.018 15.2 3.4 0.041 14.0 3.4 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Flagellin_N PF00669.20 AMK76058.1 - 0.021 14.9 4.1 0.35 11.0 0.2 2.6 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region PAS_12 PF18095.1 AMK76058.1 - 0.086 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain RNase_T PF00929.24 AMK76060.1 - 6.5e-31 108.1 0.0 1.2e-30 107.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AMK76060.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 AMK76060.1 - 2.4e-05 24.4 0.0 7.4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RNase_H superfamily GIY-YIG PF01541.24 AMK76060.1 - 8.5e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain DNA_pol_A_exo1 PF01612.20 AMK76060.1 - 0.0043 16.8 0.0 0.0085 15.8 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease Trans_reg_C PF00486.28 AMK76060.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal ArnB_C PF18677.1 AMK76060.1 - 0.19 11.8 0.1 0.44 10.7 0.1 1.6 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain GDC-P PF02347.16 AMK76061.1 - 4.8e-196 651.7 0.9 4.9e-181 602.2 0.3 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 AMK76061.1 - 6.5e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 AMK76061.1 - 2.5e-05 23.4 0.4 0.00043 19.4 0.1 2.3 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AMK76061.1 - 0.055 12.0 0.1 0.26 9.8 0.1 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme GCV_T PF01571.21 AMK76062.1 - 3.5e-87 292.0 0.0 4.4e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 AMK76062.1 - 6e-19 67.8 0.1 1.3e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain PsbW PF07123.12 AMK76062.1 - 0.028 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Acyl_transf_3 PF01757.22 AMK76063.1 - 6.8e-28 97.7 43.9 8.5e-28 97.4 43.9 1.0 1 0 0 1 1 1 1 Acyltransferase family Fer4 PF00037.27 AMK76065.1 - 1.5e-15 56.3 27.3 1.4e-06 27.9 2.5 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_9 PF13187.6 AMK76065.1 - 1.6e-12 47.3 26.8 1.4e-06 28.3 7.2 3.0 1 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK76065.1 - 3.4e-12 46.7 25.5 1.6e-06 28.6 7.4 2.5 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK76065.1 - 4.8e-09 35.9 29.3 1.4e-05 25.0 2.4 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 AMK76065.1 - 3.9e-08 34.1 24.3 0.035 15.0 2.5 4.1 4 0 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AMK76065.1 - 2.3e-07 30.8 26.0 1.4e-05 25.1 8.4 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK76065.1 - 2.9e-07 30.2 31.6 4.8e-05 23.2 4.0 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_10 PF13237.6 AMK76065.1 - 1.4e-06 28.3 33.5 0.00082 19.4 3.0 3.4 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK76065.1 - 0.00027 21.3 33.7 0.023 15.2 1.7 4.1 3 1 2 5 5 5 4 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK76065.1 - 0.0013 19.3 26.6 0.19 12.3 0.1 4.0 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK76065.1 - 0.0089 16.5 38.7 0.056 14.0 4.8 4.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_15 PF13459.6 AMK76065.1 - 0.083 13.6 0.9 0.083 13.6 0.9 4.2 3 1 1 4 4 4 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 AMK76065.1 - 2.3 9.3 42.2 1.6 9.9 5.6 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain NapD PF03927.13 AMK76066.1 - 1.1e-20 73.5 0.2 1.3e-20 73.3 0.2 1.1 1 0 0 1 1 1 1 NapD protein Molybdopterin PF00384.22 AMK76067.1 - 5.5e-96 322.1 0.6 6.7e-96 321.9 0.6 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AMK76067.1 - 5.3e-22 78.0 0.0 1.5e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AMK76067.1 - 5.6e-16 58.3 0.7 1.3e-15 57.1 0.7 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AMK76067.1 - 0.013 15.3 0.6 0.03 14.2 0.6 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence NapB PF03892.14 AMK76068.1 - 2.3e-43 147.2 2.3 2.8e-43 147.0 2.3 1.0 1 0 0 1 1 1 1 Nitrate reductase cytochrome c-type subunit (NapB) Cytochrome_C7 PF14522.6 AMK76068.1 - 0.0009 19.2 0.2 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AMK76068.1 - 0.0048 16.6 0.5 0.021 14.5 0.5 1.9 1 1 0 1 1 1 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C554 PF13435.6 AMK76068.1 - 0.019 15.9 1.8 0.83 10.6 1.5 2.2 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Cytochrom_NNT PF03264.14 AMK76068.1 - 0.022 14.5 1.7 0.047 13.4 1.7 1.5 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Cytochrom_CIII PF02085.16 AMK76068.1 - 0.028 14.8 0.2 0.041 14.2 0.2 1.3 1 0 0 1 1 1 0 Class III cytochrome C family Cytochrome_CBB3 PF13442.6 AMK76068.1 - 0.076 13.3 0.9 9.2 6.7 0.0 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_c3_2 PF14537.6 AMK76068.1 - 0.081 13.4 1.5 0.22 12.0 1.5 1.6 1 1 0 1 1 1 0 Cytochrome c3 Cytochrom_C PF00034.21 AMK76068.1 - 0.22 12.7 1.4 3.3 8.9 0.1 2.4 1 1 1 2 2 2 0 Cytochrome c Cytochrom_NNT PF03264.14 AMK76069.1 - 8.4e-74 247.0 4.9 9.6e-74 246.8 4.9 1.0 1 0 0 1 1 1 1 NapC/NirT cytochrome c family, N-terminal region Cytochrom_c3_2 PF14537.6 AMK76069.1 - 1.1e-06 29.0 14.0 0.00099 19.5 2.1 2.2 2 0 0 2 2 2 2 Cytochrome c3 Cytochrome_C7 PF14522.6 AMK76069.1 - 7.9e-05 22.6 19.2 0.0043 17.0 5.2 3.0 1 1 1 2 2 2 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AMK76069.1 - 0.00012 21.8 14.0 0.098 12.4 3.7 3.9 3 1 1 4 4 4 4 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_CIII PF02085.16 AMK76069.1 - 0.0015 18.8 18.7 0.075 13.4 5.1 2.4 1 1 0 2 2 2 2 Class III cytochrome C family DHC PF09626.10 AMK76069.1 - 0.16 12.9 0.6 0.16 12.9 0.6 3.5 1 1 1 3 3 3 0 Dihaem cytochrome c Neuropep_like PF15161.6 AMK76069.1 - 0.3 10.8 6.3 7.5 6.3 0.1 3.6 4 0 0 4 4 4 0 Neuropeptide-like zinc_ribbon_9 PF14369.6 AMK76069.1 - 2.4 8.5 8.1 25 5.3 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon Defensin_5 PF18251.1 AMK76069.1 - 3.6 7.7 11.1 27 5.0 0.4 3.9 4 0 0 4 4 4 0 Fungal defensin Copsin zinc_ribbon_15 PF17032.5 AMK76069.1 - 4.1 8.2 10.1 1.8 9.4 0.6 2.7 2 1 0 2 2 2 0 zinc-ribbon family SMI1_KNR4 PF09346.10 AMK76071.1 - 2.3e-05 24.8 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 AMK76071.1 - 0.001 18.8 0.0 0.012 15.3 0.0 2.4 1 1 1 2 2 2 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 AMK76071.1 - 0.0021 18.5 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 AMK76072.1 - 0.0023 18.3 0.2 0.005 17.3 0.1 1.6 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall Rubredoxin PF00301.20 AMK76072.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin HATPase_c PF02518.26 AMK76074.1 - 1.6e-21 76.9 0.0 2.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK76074.1 - 8e-06 25.8 0.1 2.1e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA PF00512.25 AMK76074.1 - 0.0056 16.7 2.2 0.024 14.7 0.6 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain YkyA PF10368.9 AMK76074.1 - 0.097 12.3 1.5 0.15 11.7 0.4 1.8 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Ank PF00023.30 AMK76074.1 - 0.12 12.9 0.0 0.5 10.9 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat E1_UFD PF09358.10 AMK76074.1 - 0.13 13.0 0.6 1.4 9.6 0.0 2.7 2 1 0 2 2 2 0 Ubiquitin fold domain Seryl_tRNA_N PF02403.22 AMK76075.1 - 0.53 10.5 6.0 0.86 9.9 4.8 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Flg_bb_rod PF00460.20 AMK76075.1 - 2.6 8.1 5.8 1 9.4 2.2 2.0 2 0 0 2 2 2 0 Flagella basal body rod protein HATPase_c PF02518.26 AMK76076.1 - 8.1e-23 81.1 0.0 2.2e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK76076.1 - 2.4e-17 62.7 0.3 8e-17 61.0 0.3 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK76076.1 - 9.3e-12 45.1 0.3 1.3e-10 41.5 0.0 2.8 3 0 0 3 3 3 1 HAMP domain HATPase_c_3 PF13589.6 AMK76076.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lig_C PF18330.1 AMK76076.1 - 0.074 13.1 1.0 0.3 11.1 0.0 2.5 2 1 0 2 2 2 0 Ligase Pab1020 C-terminal region Response_reg PF00072.24 AMK76077.1 - 3.2e-27 94.9 0.0 4.9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK76077.1 - 6.4e-27 93.4 0.0 1.4e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF43 PF01861.16 AMK76077.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain IF-2B PF01008.17 AMK76077.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family Leu_Phe_trans PF03588.14 AMK76078.1 - 3.5e-75 251.2 0.0 4.2e-75 250.9 0.0 1.1 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 AMK76078.1 - 0.036 14.2 0.3 0.074 13.2 0.3 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain KH_7 PF17214.3 AMK76078.1 - 0.23 11.4 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 KH domain ATE_C PF04377.15 AMK76079.1 - 1.3e-39 135.9 0.0 1.8e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 AMK76079.1 - 3.1e-19 69.1 0.1 5.4e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 AMK76079.1 - 1.8e-07 31.4 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Elong-fact-P_C PF09285.11 AMK76080.1 - 2.3e-20 72.1 0.6 4.8e-20 71.1 0.6 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 AMK76080.1 - 7.2e-16 58.0 2.3 1.4e-15 57.1 2.3 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 AMK76080.1 - 2e-15 56.5 0.5 4.9e-15 55.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Phage_hub_GP28 PF11110.8 AMK76080.1 - 0.026 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Baseplate hub distal subunit ABC_tran PF00005.27 AMK76081.1 - 1.1e-25 90.7 0.0 2.5e-25 89.6 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AMK76081.1 - 8.3e-10 39.0 0.1 1.1e-06 28.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK76081.1 - 0.0025 17.3 0.1 0.36 10.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AMK76081.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MukB PF04310.12 AMK76081.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AAA_16 PF13191.6 AMK76081.1 - 0.022 15.2 0.5 0.044 14.2 0.5 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 AMK76081.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 AMK76081.1 - 0.083 12.6 0.0 1.9 8.1 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 AMK76081.1 - 0.11 11.7 0.3 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 AMK76081.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 RsgA GTPase DUF3526 PF12040.8 AMK76082.1 - 9.1e-32 110.7 3.3 1.3e-31 110.2 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3526) ABC2_membrane_2 PF12679.7 AMK76082.1 - 1.8e-27 96.4 2.3 2.3e-27 96.1 2.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AMK76082.1 - 7.6e-12 45.0 11.7 7.6e-12 45.0 11.7 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AMK76082.1 - 4.6e-07 30.0 10.3 5.7e-07 29.7 8.8 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AMK76082.1 - 0.0013 18.3 5.4 0.0024 17.4 4.7 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF3526 PF12040.8 AMK76083.1 - 2.2e-18 67.2 1.0 3.6e-18 66.5 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3526) ABC2_membrane_2 PF12679.7 AMK76083.1 - 5e-07 29.3 0.9 6.8e-07 28.9 0.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AMK76083.1 - 0.015 14.4 0.5 0.027 13.6 0.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Aminotran_4 PF01063.19 AMK76085.1 - 2.5e-54 184.5 0.0 3e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV FNIP_N PF14636.6 AMK76085.1 - 0.12 13.4 0.1 0.32 12.0 0.1 1.7 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Glyco_transf_9 PF01075.17 AMK76086.1 - 5.3e-68 229.0 0.0 6.5e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) zf-LYAR PF08790.11 AMK76086.1 - 0.22 11.4 0.1 0.46 10.4 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Glyco_transf_9 PF01075.17 AMK76087.1 - 6.4e-38 130.5 0.0 8.8e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) DUF3391 PF11871.8 AMK76088.1 - 4.3e-14 53.2 0.0 5.5e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3391) HD PF01966.22 AMK76089.1 - 2.3e-11 44.0 0.0 3.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AMK76089.1 - 4.1e-10 39.8 0.0 7.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF3391 PF11871.8 AMK76089.1 - 5e-08 33.6 0.0 1.2e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3391) HDOD PF08668.12 AMK76089.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Peptidase_A3 PF02160.15 AMK76089.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Wzz PF02706.15 AMK76090.1 - 0.0028 17.9 2.5 0.0035 17.6 0.1 2.4 2 0 0 2 2 2 1 Chain length determinant protein LodA_N PF17990.1 AMK76090.1 - 0.24 11.3 6.8 0.06 13.3 2.5 2.0 2 0 0 2 2 2 0 L-Lysine epsilon oxidase N-terminal Fib_alpha PF08702.10 AMK76090.1 - 0.29 11.3 23.3 0.17 12.1 1.0 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family PspB PF06667.12 AMK76090.1 - 0.45 10.6 3.7 0.84 9.7 0.1 3.0 2 0 0 2 2 2 0 Phage shock protein B Phlebovirus_NSM PF07246.11 AMK76090.1 - 0.45 9.8 10.7 0.23 10.8 2.5 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Tau95 PF09734.9 AMK76090.1 - 0.72 10.7 4.0 1.7 9.5 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF2408 PF10303.9 AMK76090.1 - 1.1 9.8 13.7 1.4 9.5 4.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PIN_8 PF18476.1 AMK76090.1 - 1.2 9.0 23.3 1.3 8.8 6.8 2.8 2 1 1 3 3 3 0 PIN like domain LOH1CR12 PF10158.9 AMK76090.1 - 1.4 8.9 10.2 0.45 10.5 2.1 3.1 1 1 2 3 3 3 0 Tumour suppressor protein Occludin_ELL PF07303.13 AMK76090.1 - 7 7.4 14.8 2 9.2 8.5 3.1 1 1 1 2 2 2 0 Occludin homology domain CorA PF01544.18 AMK76090.1 - 8.8 5.6 18.6 4.1 6.6 3.5 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cupin_3 PF05899.12 AMK76091.1 - 4.1e-24 84.1 0.1 5.3e-24 83.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 AMK76091.1 - 1.6e-07 30.9 0.2 2.4e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 AMK76091.1 - 0.0037 17.0 0.0 0.004 16.9 0.0 1.1 1 0 0 1 1 1 1 Cupin BACON PF13004.7 AMK76091.1 - 0.049 13.6 0.5 0.25 11.4 0.5 1.9 1 1 0 1 1 1 0 Putative binding domain, N-terminal Biotin_lipoyl_2 PF13533.6 AMK76092.1 - 1.5e-14 53.6 9.2 3.1e-13 49.3 0.3 3.7 3 1 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 AMK76092.1 - 1.8e-13 51.1 3.7 1.2e-08 35.5 0.2 2.8 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK76092.1 - 1.5e-12 47.2 2.8 2.5e-12 46.5 2.8 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AMK76092.1 - 0.0004 20.2 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 Biotin-requiring enzyme VWA_3_C PF18571.1 AMK76092.1 - 0.041 13.7 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain DUF4131 PF13567.6 AMK76092.1 - 0.068 12.8 0.3 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EF-hand_12 PF17901.1 AMK76092.1 - 0.15 12.5 0.1 22 5.6 0.1 2.4 2 0 0 2 2 2 0 EF-hand fold domain ACR_tran PF00873.19 AMK76093.1 - 0 1091.1 25.9 0 1090.9 25.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK76093.1 - 3.3e-09 36.1 15.9 3.3e-09 36.1 15.9 3.0 2 2 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 AMK76093.1 - 0.00011 21.7 14.3 0.00011 21.7 14.3 2.7 3 0 0 3 3 3 2 Protein export membrane protein ACR_tran PF00873.19 AMK76094.1 - 0 1087.4 8.1 0 1087.3 8.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK76094.1 - 1.5e-07 30.7 28.4 1.3e-06 27.6 8.8 2.9 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 AMK76094.1 - 0.0013 18.2 17.2 0.016 14.6 9.6 2.5 2 0 0 2 2 2 2 Protein export membrane protein EAL PF00563.20 AMK76095.1 - 2.9e-71 239.8 0.0 5.3e-71 238.9 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK76095.1 - 6e-50 169.1 0.0 1.1e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 AMK76095.1 - 7.5e-13 48.6 0.0 2.6e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 HAMP domain GAF_3 PF13492.6 AMK76095.1 - 0.076 13.4 0.1 2.1 8.7 0.0 3.2 3 0 0 3 3 3 0 GAF domain T2SSG PF08334.11 AMK76096.1 - 5.4e-06 26.5 1.9 0.023 14.7 1.9 3.1 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein G ComP_DUS PF16732.5 AMK76096.1 - 1.2e-05 26.0 0.0 1.7e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Type IV minor pilin ComP, DNA uptake sequence receptor N_methyl PF07963.12 AMK76096.1 - 1.9e-05 24.0 5.8 3.3e-05 23.2 5.8 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif NDUF_B12 PF08122.12 AMK76096.1 - 0.069 13.2 0.2 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF3391 PF11871.8 AMK76097.1 - 2.5e-23 83.1 0.0 4.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HD PF01966.22 AMK76097.1 - 3.1e-11 43.5 0.0 8.8e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AMK76097.1 - 7.7e-11 42.1 0.0 1.9e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AMK76097.1 - 0.03 13.8 0.1 0.085 12.3 0.1 1.8 1 1 0 1 1 1 0 HDOD domain Fer4_NifH PF00142.18 AMK76098.1 - 5.7e-137 455.6 4.3 6.5e-137 455.4 4.3 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 AMK76098.1 - 1.1e-11 45.0 1.1 1.5e-10 41.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 AMK76098.1 - 1.7e-11 44.3 0.0 2.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AMK76098.1 - 3.4e-08 33.2 1.7 3.7e-06 26.6 0.2 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 AMK76098.1 - 6.5e-06 25.5 0.2 2.7e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 AMK76098.1 - 9e-05 21.6 0.0 0.00022 20.3 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 AMK76098.1 - 0.0012 19.0 0.1 0.007 16.5 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain CBP_BcsQ PF06564.12 AMK76098.1 - 0.0036 16.8 0.4 2 7.9 0.0 2.2 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AMK76098.1 - 0.0045 16.3 0.2 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 ATPase MipZ AAA_24 PF13479.6 AMK76098.1 - 0.0053 16.5 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 AMK76098.1 - 0.014 15.0 0.1 0.035 13.7 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AMK76098.1 - 0.016 15.5 0.2 0.33 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.7 AMK76098.1 - 0.018 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain CLP1_P PF16575.5 AMK76098.1 - 0.032 14.0 0.4 0.066 13.0 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 AMK76098.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AMK76098.1 - 0.051 14.0 0.2 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 AMK76098.1 - 0.079 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Phospholamban PF04272.14 AMK76098.1 - 0.099 12.1 0.1 0.32 10.5 0.2 1.8 2 0 0 2 2 2 0 Phospholamban Oxidored_nitro PF00148.19 AMK76099.1 - 7.3e-110 367.4 0.0 8.6e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF5591 PF17884.1 AMK76099.1 - 0.085 12.7 0.7 4.1 7.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5591) Oxidored_nitro PF00148.19 AMK76100.1 - 5.8e-120 400.7 0.0 6.8e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF3364 PF11844.8 AMK76100.1 - 9.5e-24 83.4 4.3 2.2e-23 82.3 4.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3364) HAUS-augmin3 PF14932.6 AMK76100.1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NifT PF06988.11 AMK76101.1 - 1.1e-24 85.9 0.0 1.3e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 NifT/FixU protein Fer4_9 PF13187.6 AMK76102.1 - 7.3e-08 32.5 22.3 2.8e-05 24.2 12.9 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK76102.1 - 4.6e-07 30.3 24.4 0.00041 20.9 14.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AMK76102.1 - 5.2e-07 29.2 19.5 1.3e-06 27.9 3.4 3.4 3 1 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AMK76102.1 - 6.1e-06 26.0 16.3 0.00056 19.9 2.8 2.5 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AMK76102.1 - 8.9e-06 25.7 15.4 2.3e-05 24.4 14.5 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK76102.1 - 1.5e-05 25.0 18.9 5.8e-05 23.1 18.9 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK76102.1 - 2.2e-05 24.3 18.2 0.00022 21.2 2.7 2.7 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AMK76102.1 - 5e-05 24.0 17.2 0.029 15.3 3.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AMK76102.1 - 0.00021 22.1 5.9 0.00021 22.1 5.9 2.3 1 1 1 2 2 2 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AMK76102.1 - 0.0084 16.5 11.6 0.031 14.7 2.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK76102.1 - 0.011 16.3 2.7 0.011 16.3 2.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain GF_recep_IV PF14843.6 AMK76102.1 - 0.011 15.6 7.9 0.015 15.1 7.9 1.3 1 0 0 1 1 1 0 Growth factor receptor domain IV Fer4_4 PF12800.7 AMK76102.1 - 0.06 13.9 20.1 0.11 13.0 3.4 2.9 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AMK76102.1 - 0.14 12.3 15.3 0.047 13.9 6.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Nitro_FeMo-Co PF02579.17 AMK76103.1 - 1.7e-18 66.7 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor DIMCO_N PF16844.5 AMK76103.1 - 9.4e-12 45.1 0.2 2e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor, N-terminal LRV PF01816.17 AMK76105.1 - 5.9e-25 85.9 29.7 0.00042 20.5 1.1 7.4 7 0 0 7 7 7 7 Leucine rich repeat variant HEAT PF02985.22 AMK76105.1 - 5.5e-13 48.0 13.7 0.13 12.6 0.1 8.1 7 1 1 8 8 8 4 HEAT repeat LRV_FeS PF05484.11 AMK76105.1 - 9.7e-13 47.9 0.1 1.8e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 LRV protein FeS4 cluster HEAT_2 PF13646.6 AMK76105.1 - 4.7e-07 30.1 14.4 1 9.8 0.5 6.6 1 1 1 3 3 3 3 HEAT repeats DUF3572 PF12096.8 AMK76105.1 - 0.085 13.1 0.3 20 5.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3572) DUF772 PF05598.11 AMK76108.1 - 3.2e-22 78.3 0.7 3e-21 75.2 0.3 2.7 2 1 1 3 3 3 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AMK76108.1 - 6.8e-14 52.0 0.5 1.9e-13 50.6 0.5 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK76108.1 - 5.9e-08 33.0 0.1 1.5e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AMK76108.1 - 2.8e-05 24.4 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76108.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Methyltransf_21 PF05050.12 AMK76109.1 - 1e-10 41.9 0.1 1.9e-10 41.0 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF3435 PF11917.8 AMK76109.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Glyco_transf_25 PF01755.17 AMK76110.1 - 1.3e-21 77.4 0.4 7.3e-21 74.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Popeye PF04831.13 AMK76111.1 - 0.9 9.7 3.5 0.66 10.1 0.4 2.3 2 0 0 2 2 2 0 Popeye protein conserved region ZapA PF05164.13 AMK76112.1 - 5.2e-19 68.5 0.6 6.4e-19 68.2 0.6 1.1 1 0 0 1 1 1 1 Cell division protein ZapA Rbsn PF11464.8 AMK76112.1 - 0.14 11.9 0.4 0.27 11.0 0.1 1.6 2 0 0 2 2 2 0 Rabenosyn Rab binding domain ZapB PF06005.12 AMK76113.1 - 0.00065 20.1 6.4 0.00085 19.7 6.4 1.1 1 0 0 1 1 1 1 Cell division protein ZapB Sec34 PF04136.15 AMK76113.1 - 0.0063 16.4 1.5 0.0068 16.3 1.5 1.1 1 0 0 1 1 1 1 Sec34-like family HALZ PF02183.18 AMK76113.1 - 0.012 15.8 5.9 0.15 12.3 4.9 2.8 1 1 1 2 2 2 0 Homeobox associated leucine zipper BLYB PF05289.11 AMK76113.1 - 0.034 14.3 1.0 0.045 14.0 1.0 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein TIP39 PF14980.6 AMK76113.1 - 0.039 13.8 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 TIP39 peptide JIP_LZII PF16471.5 AMK76113.1 - 0.069 13.3 3.7 0.18 12.0 3.7 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II YabA PF06156.13 AMK76113.1 - 0.07 13.8 2.8 0.082 13.5 2.8 1.2 1 0 0 1 1 1 0 Initiation control protein YabA EMP24_GP25L PF01105.24 AMK76113.1 - 0.07 13.1 0.8 0.084 12.8 0.6 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6_N PF17675.1 AMK76113.1 - 0.074 13.6 6.6 0.11 13.0 6.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 AMK76113.1 - 0.1 12.4 4.2 0.15 11.9 3.2 1.7 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 AMK76113.1 - 0.12 10.3 2.9 0.11 10.4 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 AMK76113.1 - 0.2 12.0 6.6 0.21 12.0 6.6 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HAUS-augmin3 PF14932.6 AMK76113.1 - 0.26 10.8 5.8 0.27 10.8 5.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF5320 PF17253.2 AMK76113.1 - 8.5 7.5 5.4 4.3 8.5 0.6 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) UPF0149 PF03695.13 AMK76114.1 - 5.5e-28 98.4 5.1 6.1e-28 98.3 5.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) Viral_DNA_bp PF00747.17 AMK76114.1 - 0.0089 13.3 0.3 0.011 12.9 0.3 1.1 1 0 0 1 1 1 1 ssDNA binding protein Peptidase_M24 PF00557.24 AMK76115.1 - 3.9e-64 216.2 0.0 6.2e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 AMK76115.1 - 1.1e-36 125.2 0.0 2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 AMK76115.1 - 0.036 14.7 0.0 0.066 13.9 0.0 1.5 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain DUF903 PF06004.12 AMK76115.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) FAD_binding_3 PF01494.19 AMK76116.1 - 6.2e-39 134.2 0.6 7.1e-39 134.0 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 AMK76116.1 - 5.6e-06 25.6 0.0 1.4e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 AMK76116.1 - 4.9e-05 22.6 1.3 4.9e-05 22.6 1.3 2.1 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 AMK76116.1 - 9.1e-05 21.7 1.3 0.00015 21.0 1.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 AMK76116.1 - 0.00013 21.2 1.4 0.003 16.7 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AMK76116.1 - 0.00021 20.6 0.7 0.0004 19.7 0.7 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AMK76116.1 - 0.001 19.3 0.2 0.0031 17.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK76116.1 - 0.0014 18.3 1.5 0.0041 16.8 0.2 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AMK76116.1 - 0.016 14.6 0.6 0.051 12.9 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 AMK76116.1 - 0.068 11.9 0.3 0.23 10.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 AMK76116.1 - 0.076 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 AMK76116.1 - 0.13 12.8 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_17 PF00332.18 AMK76118.1 - 1.3e-06 28.2 0.2 2.8e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Transglut_core PF01841.19 AMK76119.1 - 3.5e-24 85.4 0.0 5.3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Bact_transglu_N PF08379.10 AMK76119.1 - 1.4e-05 25.8 0.0 2.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core3 PF13471.6 AMK76119.1 - 0.00026 20.9 0.1 0.00049 20.0 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF21 PF01595.20 AMK76120.1 - 1e-47 162.1 0.1 1.5e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AMK76120.1 - 1.9e-17 63.1 0.1 4e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AMK76120.1 - 6.3e-07 29.7 0.0 0.037 14.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain G6PD_C PF02781.16 AMK76121.1 - 7.8e-118 392.9 0.0 9.7e-118 392.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 AMK76121.1 - 6.8e-57 192.9 0.0 1.2e-56 192.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Response_reg PF00072.24 AMK76122.1 - 1.1e-27 96.4 0.0 2.6e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Hpt PF01627.23 AMK76122.1 - 0.0049 17.1 0.3 0.014 15.7 0.1 1.9 2 0 0 2 2 2 1 Hpt domain Pterin_4a PF01329.19 AMK76122.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.3 3 0 0 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase Cpn60_TCP1 PF00118.24 AMK76123.1 - 5.7e-95 318.8 19.6 9.3e-95 318.1 19.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn10 PF00166.21 AMK76124.1 - 2.1e-36 123.8 0.6 2.3e-36 123.7 0.6 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ThiF PF00899.21 AMK76125.1 - 2.6e-65 220.2 0.1 3e-65 220.0 0.1 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 AMK76125.1 - 2.5e-06 27.8 0.3 6.8e-06 26.4 0.3 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 AMK76125.1 - 0.0013 19.1 0.1 0.003 18.0 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 AMK76125.1 - 0.0014 18.7 0.1 0.0048 17.0 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AMK76125.1 - 0.0027 17.3 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 AMK76125.1 - 0.0063 15.8 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 AMK76125.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 AMK76125.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AMK76125.1 - 0.023 14.0 0.2 0.035 13.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AMK76125.1 - 0.029 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 AMK76125.1 - 0.038 14.1 0.7 0.076 13.1 0.3 1.8 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PglD_N PF17836.1 AMK76125.1 - 0.071 13.7 0.1 0.14 12.8 0.1 1.5 1 0 0 1 1 1 0 PglD N-terminal domain DAO PF01266.24 AMK76125.1 - 0.14 11.8 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase E1-E2_ATPase PF00122.20 AMK76127.1 - 1.8e-53 180.7 0.4 5.6e-53 179.1 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AMK76127.1 - 1.3e-43 148.9 10.3 1.3e-43 148.9 10.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AMK76127.1 - 1.1e-21 78.1 2.5 3.9e-20 73.0 2.5 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AMK76127.1 - 4.7e-18 65.1 0.0 9.7e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 AMK76127.1 - 1.7e-17 62.8 0.4 2e-16 59.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AMK76127.1 - 1.3e-06 28.4 1.0 7e-05 22.7 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK76127.1 - 0.0025 18.3 0.3 0.0049 17.3 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TetR_N PF00440.23 AMK76128.1 - 1.6e-13 50.2 0.0 3.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 AMK76128.1 - 0.031 14.4 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF1348 PF07080.11 AMK76129.1 - 1e-65 219.5 7.0 1.2e-65 219.3 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 AMK76129.1 - 4.4e-09 36.9 2.0 5.6e-09 36.6 1.5 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AMK76129.1 - 0.0005 20.4 0.2 0.00068 20.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 AMK76129.1 - 0.00055 19.7 0.3 0.00084 19.1 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PFK PF00365.20 AMK76130.1 - 1.3e-37 129.7 0.4 3.7e-37 128.2 0.4 1.8 1 1 0 1 1 1 1 Phosphofructokinase Abhydrolase_1 PF00561.20 AMK76132.1 - 2e-25 89.9 0.7 3.4e-24 85.9 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK76132.1 - 9.5e-20 72.1 3.8 1.1e-19 71.9 3.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK76132.1 - 9.6e-14 51.2 0.4 1.5e-13 50.6 0.4 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 AMK76132.1 - 2.5e-05 24.1 0.1 0.08 12.6 0.1 2.2 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 AMK76132.1 - 8.8e-05 22.7 0.1 0.00011 22.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 AMK76132.1 - 0.00083 19.1 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 AMK76132.1 - 0.0017 17.1 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 AMK76132.1 - 0.026 13.8 0.0 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 AMK76132.1 - 0.2 11.2 0.1 0.53 9.7 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF445 PF04286.12 AMK76133.1 - 2.3e-14 54.0 1.2 4.1e-07 30.1 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF445) DNA_binding_1 PF01035.20 AMK76134.1 - 2.8e-33 113.9 0.0 3.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DNA_topoisoIV PF00521.20 AMK76135.1 - 3.7e-134 447.8 0.0 4.5e-134 447.5 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AMK76135.1 - 2.4e-12 46.1 0.0 0.00011 21.6 0.0 3.5 3 0 0 3 3 3 2 DNA gyrase C-terminal domain, beta-propeller DUF4890 PF16231.5 AMK76135.1 - 0.09 13.3 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) SWIRM-assoc_1 PF16495.5 AMK76135.1 - 0.19 11.7 5.7 0.42 10.6 5.7 1.6 1 0 0 1 1 1 0 SWIRM-associated region 1 HTH_Crp_2 PF13545.6 AMK76136.1 - 2.8e-18 65.6 0.4 6.1e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AMK76136.1 - 3.6e-15 55.8 0.0 6.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Crp PF00325.20 AMK76136.1 - 1.2e-12 47.2 0.1 2.5e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR PF01047.22 AMK76136.1 - 0.026 14.4 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 AMK76136.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_36 PF13730.6 AMK76136.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GDPD PF03009.17 AMK76137.1 - 5.5e-51 173.8 0.0 8.5e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 AMK76137.1 - 0.0047 17.3 0.0 0.053 14.0 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_5 PF13202.6 AMK76137.1 - 0.42 10.2 4.2 3.7 7.2 0.7 2.7 2 0 0 2 2 2 0 EF hand PhoD PF09423.10 AMK76138.1 - 9.7e-84 281.4 0.1 1.1e-83 281.1 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 AMK76138.1 - 1.1e-13 51.5 0.1 2.8e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain p450 PF00067.22 AMK76139.1 - 1.5e-20 73.5 0.6 3e-19 69.1 0.7 2.1 1 1 0 1 1 1 1 Cytochrome P450 GST_C_2 PF13410.6 AMK76139.1 - 1.6e-07 31.3 0.5 4.6e-07 29.8 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AMK76139.1 - 9.7e-05 22.5 0.0 0.0003 20.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AMK76139.1 - 0.0062 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 AMK76139.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain YndJ PF14158.6 AMK76140.1 - 0.022 14.1 1.2 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 YndJ-like protein Dyp_perox PF04261.12 AMK76141.1 - 2.8e-07 29.9 0.2 7e-06 25.2 0.2 2.9 1 1 0 1 1 1 1 Dyp-type peroxidase family SLT PF01464.20 AMK76143.1 - 1.4e-29 102.2 0.0 2.5e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Sel1 PF08238.12 AMK76143.1 - 3.7e-12 46.5 2.8 1.8e-06 28.4 0.1 2.8 3 0 0 3 3 3 2 Sel1 repeat Phage_lysozyme2 PF18013.1 AMK76143.1 - 0.041 13.9 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail lysozyme GGDEF PF00990.21 AMK76144.1 - 9.7e-53 178.2 0.2 1.7e-52 177.4 0.2 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Spc7 PF08317.11 AMK76144.1 - 0.032 13.1 2.3 0.044 12.7 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Guanylate_cyc PF00211.20 AMK76144.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DUF4407 PF14362.6 AMK76144.1 - 0.067 12.5 3.1 0.1 11.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 AMK76144.1 - 0.89 9.7 7.2 1.8 8.6 7.2 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ABC_tran_CTD PF16326.5 AMK76144.1 - 6.4 7.1 10.6 7.1 7.0 5.9 3.0 3 1 0 3 3 3 0 ABC transporter C-terminal domain PEP-utilisers_N PF05524.13 AMK76144.1 - 6.4 7.0 8.5 4.5 7.5 3.0 3.1 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal DUF2797 PF10977.8 AMK76145.1 - 1.4e-96 322.9 0.0 1.6e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) Cript PF10235.9 AMK76145.1 - 2.9 8.5 8.7 2.5 8.7 7.1 1.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Ala_racemase_N PF01168.20 AMK76146.1 - 4.6e-60 203.0 0.1 5.8e-60 202.6 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 AMK76146.1 - 4e-41 139.7 0.2 9.8e-41 138.4 0.2 1.6 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain DnaB_C PF03796.15 AMK76147.1 - 2.1e-117 391.0 0.0 2.7e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AMK76147.1 - 1.6e-35 121.3 0.0 3.2e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AMK76147.1 - 3.1e-13 49.8 0.0 5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AMK76147.1 - 2.9e-06 26.8 0.0 3e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 KaiC CbiA PF01656.23 AMK76147.1 - 0.036 14.1 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 AMK76147.1 - 0.044 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 AMK76147.1 - 0.047 14.0 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ParA PF10609.9 AMK76147.1 - 0.049 13.1 1.4 0.12 11.8 0.2 2.1 2 1 1 3 3 3 0 NUBPL iron-transfer P-loop NTPase RuvB_N PF05496.12 AMK76147.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AMK76147.1 - 0.097 13.1 0.1 0.47 10.9 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AMK76147.1 - 0.11 12.7 0.2 0.89 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 AMK76147.1 - 0.14 12.0 0.1 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 AMK76147.1 - 0.16 11.7 0.0 4.1 7.1 0.0 2.9 4 0 0 4 4 4 0 AAA domain HD PF01966.22 AMK76148.1 - 5.3e-29 100.9 2.7 4.2e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 HD domain HD_5 PF13487.6 AMK76148.1 - 1.2e-12 47.9 0.3 1.2e-09 38.3 0.0 2.9 3 0 0 3 3 3 2 HD domain HDOD PF08668.12 AMK76148.1 - 1.7e-09 37.5 0.1 2.2e-05 24.0 0.0 2.7 2 1 1 3 3 3 2 HDOD domain Utp13 PF08625.11 AMK76148.1 - 0.14 12.0 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain PEP-CTERM PF07589.11 AMK76149.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 2.0 2 0 0 2 2 2 1 PEP-CTERM motif W_rich_C PF07483.11 AMK76150.1 - 0.062 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain ACR_tran PF00873.19 AMK76151.1 - 8.7e-226 752.0 12.9 1.1e-225 751.7 12.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK76151.1 - 2.9e-06 26.5 25.9 0.0002 20.4 6.0 2.7 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AMK76151.1 - 0.0006 19.3 19.1 0.017 14.5 8.4 2.4 2 0 0 2 2 2 2 Protein export membrane protein HEPN_RiboL-PSP PF18735.1 AMK76152.1 - 0.00098 19.1 0.2 0.0016 18.4 0.0 1.5 2 0 0 2 2 2 1 RiboL-PSP-HEPN HEPN_MAE_28990 PF18737.1 AMK76152.1 - 0.0091 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 MAE_28990/MAE_18760-like HEPN DUF4145 PF13643.6 AMK76152.1 - 0.015 15.4 0.4 0.033 14.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) HI0933_like PF03486.14 AMK76152.1 - 0.04 12.6 0.0 0.23 10.1 0.1 1.8 1 1 1 2 2 2 0 HI0933-like protein HEPN PF05168.14 AMK76152.1 - 0.042 14.0 0.1 0.078 13.1 0.1 1.5 1 0 0 1 1 1 0 HEPN domain YoeB_toxin PF06769.14 AMK76153.1 - 6.5e-42 141.5 0.2 7.2e-42 141.3 0.2 1.0 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system ParE_toxin PF05016.15 AMK76153.1 - 0.0004 20.9 0.0 0.00042 20.9 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE PhdYeFM_antitox PF02604.19 AMK76154.1 - 1.3e-21 76.1 0.0 1.7e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AMK76154.1 - 0.014 15.5 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Sua5_yciO_yrdC PF01300.18 AMK76155.1 - 4.3e-53 179.5 0.0 7.1e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination zf-HYPF PF07503.12 AMK76155.1 - 2.7e-34 116.6 18.6 5.4e-17 61.3 5.3 2.9 2 0 0 2 2 2 2 HypF finger HypF_C PF17788.1 AMK76155.1 - 7.9e-34 116.4 1.5 1.5e-33 115.5 1.5 1.5 1 0 0 1 1 1 1 HypF Kae1-like domain Acylphosphatase PF00708.18 AMK76155.1 - 2.5e-16 59.8 0.0 4.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Acylphosphatase Peptidase_M22 PF00814.25 AMK76155.1 - 2.1e-08 34.2 0.1 4e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Glycoprotease family FGGY_C PF02782.16 AMK76155.1 - 0.00032 20.5 0.2 0.00068 19.4 0.2 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DZR PF12773.7 AMK76155.1 - 0.26 11.4 13.1 1.3 9.1 1.1 2.6 1 1 0 2 2 2 0 Double zinc ribbon AIRS_C PF02769.22 AMK76156.1 - 1.2e-28 100.3 0.8 1.6e-28 99.8 0.8 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AMK76156.1 - 1.3e-16 61.0 2.9 2e-16 60.4 1.1 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Cytochrome_CBB3 PF13442.6 AMK76157.1 - 0.013 15.8 0.8 0.018 15.4 0.8 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III HypD PF01924.16 AMK76158.1 - 4e-157 522.8 0.0 4.5e-157 522.6 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family HupF_HypC PF01455.18 AMK76159.1 - 1.4e-27 95.6 0.2 1.6e-27 95.4 0.2 1.0 1 0 0 1 1 1 1 HupF/HypC family cobW PF02492.19 AMK76160.1 - 1.4e-36 125.7 0.0 1.8e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 AMK76160.1 - 0.03 14.2 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 AMK76160.1 - 0.068 12.6 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Zeta_toxin PF06414.12 AMK76160.1 - 0.074 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 AMK76160.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AMK76160.1 - 0.11 12.5 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Zip PF02535.22 AMK76160.1 - 1.1 8.5 4.7 1.4 8.1 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HypA PF01155.19 AMK76161.1 - 5.2e-34 116.6 3.4 5.8e-34 116.5 3.4 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5629 PF18629.1 AMK76161.1 - 0.029 14.9 0.0 0.038 14.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5629) NiFeSe_Hases PF00374.19 AMK76162.1 - 1.1e-10 41.0 0.0 1e-05 24.7 0.0 3.0 2 1 1 3 3 3 3 Nickel-dependent hydrogenase Homez PF11569.8 AMK76162.1 - 0.11 12.0 0.5 0.32 10.5 0.2 1.9 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez NiFe-hyd_HybE PF11939.8 AMK76163.1 - 1.1e-48 165.0 0.2 1.3e-48 164.8 0.2 1.0 1 0 0 1 1 1 1 [NiFe]-hydrogenase assembly, chaperone, HybE gpW PF02831.15 AMK76163.1 - 0.14 12.1 0.7 1.3 9.0 0.2 2.1 2 0 0 2 2 2 0 gpW Rubredoxin PF00301.20 AMK76164.1 - 1.5e-22 79.4 4.7 1.9e-22 79.0 4.7 1.2 1 0 0 1 1 1 1 Rubredoxin PHD_4 PF16866.5 AMK76164.1 - 1.9e-05 24.7 0.5 2.6e-05 24.2 0.5 1.2 1 0 0 1 1 1 1 PHD-finger RbpA PF13397.6 AMK76164.1 - 0.094 13.3 0.1 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase-binding protein Zn-ribbon_8 PF09723.10 AMK76164.1 - 0.14 12.3 0.9 0.57 10.4 0.9 1.9 1 1 0 1 1 1 0 Zinc ribbon domain HupH_C PF04809.13 AMK76165.1 - 1.9e-67 224.3 0.9 5.2e-50 168.1 0.0 2.1 2 0 0 2 2 2 2 HupH hydrogenase expression protein, C-terminal conserved region ParE_toxin PF05016.15 AMK76167.1 - 1e-07 32.5 0.2 1.1e-07 32.3 0.2 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Unstab_antitox PF09720.10 AMK76168.1 - 2.5e-12 46.6 0.8 3.5e-12 46.2 0.8 1.2 1 0 0 1 1 1 1 Putative addiction module component HyaE PF07449.11 AMK76169.1 - 4.6e-31 107.0 0.0 5.3e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE HupF_HypC PF01455.18 AMK76170.1 - 1.1e-18 67.1 0.6 1.4e-18 66.8 0.6 1.1 1 0 0 1 1 1 1 HupF/HypC family HycI PF01750.18 AMK76171.1 - 1.8e-43 147.5 0.0 2.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease Ni_hydr_CYTB PF01292.20 AMK76172.1 - 8.1e-25 87.5 18.5 1.2e-24 87.0 18.5 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AMK76172.1 - 3e-06 27.7 24.3 3.3e-06 27.6 12.9 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4405) DUF347 PF03988.12 AMK76173.1 - 0.0034 17.5 0.9 0.0034 17.5 0.9 1.7 2 0 0 2 2 2 1 Repeat of Unknown Function (DUF347) DIM PF08194.12 AMK76173.1 - 1.3 9.3 4.3 24 5.2 1.2 2.3 2 0 0 2 2 2 0 DIM protein FixS PF03597.15 AMK76173.1 - 6 6.7 9.8 0.21 11.3 3.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type NiFeSe_Hases PF00374.19 AMK76174.1 - 1.1e-225 750.3 0.0 1.2e-225 750.2 0.0 1.0 1 0 0 1 1 1 1 Nickel-dependent hydrogenase NiFe_hyd_SSU_C PF14720.6 AMK76175.1 - 1.6e-32 111.6 5.9 1.6e-32 111.6 5.9 2.0 2 0 0 2 2 2 1 NiFe/NiFeSe hydrogenase small subunit C-terminal Oxidored_q6 PF01058.22 AMK76175.1 - 2.6e-27 95.2 1.4 4.3e-27 94.5 1.4 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TAT_signal PF10518.9 AMK76175.1 - 0.026 14.4 0.6 0.026 14.4 0.6 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PepSY_TM PF03929.16 AMK76176.1 - 0.03 14.0 0.2 0.038 13.7 0.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region MCM3AP_GANP PF16769.5 AMK76176.1 - 0.2 9.9 4.9 0.22 9.7 4.9 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Atrophin-1 PF03154.15 AMK76176.1 - 1.4 7.1 8.1 1.6 6.9 8.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ferric_reduct PF01794.19 AMK76179.1 - 5.2e-18 65.4 7.9 5.2e-18 65.4 7.9 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DNA_binding_2 PF13724.6 AMK76179.1 - 0.29 11.6 1.3 2.2 8.8 0.1 2.4 2 0 0 2 2 2 0 DNA-binding domain DUF3619 PF12279.8 AMK76179.1 - 0.54 10.6 2.9 7.6 6.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) DUF4013 PF13197.6 AMK76179.1 - 0.95 9.3 11.5 0.19 11.6 6.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Oxidored_molyb PF00174.19 AMK76180.1 - 9.2e-31 106.8 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain CytB6-F_Fe-S PF08802.10 AMK76180.1 - 0.062 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit MazG PF03819.17 AMK76182.1 - 3.9e-41 139.1 1.1 9.5e-28 96.2 0.0 2.5 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 AMK76182.1 - 1.1e-09 38.6 0.7 7.3e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 AMK76182.1 - 0.0007 19.8 0.1 0.0023 18.1 0.0 1.9 2 0 0 2 2 2 1 MazG-like family BrnT_toxin PF04365.13 AMK76182.1 - 0.045 14.1 0.5 0.49 10.8 0.0 2.7 2 1 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system FliS PF02561.14 AMK76182.1 - 0.057 13.7 0.2 0.74 10.1 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliS Cytochrom_C_2 PF01322.20 AMK76182.1 - 0.093 13.6 1.4 66 4.4 0.0 3.2 2 1 0 3 3 3 0 Cytochrome C' Epsilon_antitox PF08998.11 AMK76182.1 - 0.11 12.8 0.5 0.6 10.4 0.1 2.3 1 1 1 2 2 2 0 Bacterial epsilon antitoxin YcbB PF08664.10 AMK76182.1 - 0.15 12.1 1.0 0.76 9.8 0.7 2.4 1 1 0 1 1 1 0 YcbB domain PfkB PF00294.24 AMK76183.1 - 5.7e-36 124.4 0.0 7.4e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase GAF PF01590.26 AMK76183.1 - 0.05 14.2 0.0 0.24 12.0 0.0 2.1 1 1 1 2 2 2 0 GAF domain DAGK_prokar PF01219.19 AMK76184.1 - 6.6e-34 115.8 3.5 7.6e-34 115.6 3.5 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase GCV_H PF01597.19 AMK76185.1 - 9.6e-41 138.5 0.1 1.1e-40 138.4 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 AMK76185.1 - 4.5e-05 23.2 0.1 7.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 AMK76185.1 - 0.012 16.3 0.2 1.9 9.2 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.6 AMK76185.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 AMK76185.1 - 0.094 12.6 0.2 11 5.9 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like SOSSC PF15925.5 AMK76186.1 - 5.1 8.5 0.0 5.1 8.5 0.0 3.2 2 1 0 2 2 2 0 SOSS complex subunit C Glyco_trans_1_3 PF13528.6 AMK76187.1 - 1.1e-38 133.4 0.0 1.4e-37 129.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.16 AMK76187.1 - 0.043 13.8 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain PAP2 PF01569.21 AMK76188.1 - 2.8e-24 85.4 2.4 2.8e-24 85.4 2.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AMK76188.1 - 9.9e-09 35.2 14.4 2.2e-07 30.8 14.4 2.0 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 AMK76188.1 - 1.1 9.9 9.8 0.14 12.7 1.5 2.7 2 1 0 2 2 2 0 PAP2 superfamily C-terminal SPC12 PF06645.13 AMK76188.1 - 1.8 8.7 6.0 2 8.6 1.2 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TrkH PF02386.16 AMK76189.1 - 1.3e-71 241.6 8.1 2.2e-43 148.5 0.7 2.0 2 0 0 2 2 2 2 Cation transport protein SecD_SecF PF02355.16 AMK76190.1 - 8.5e-66 221.0 11.5 1.1e-65 220.5 11.5 1.1 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 AMK76190.1 - 2.1e-10 39.7 0.1 5.1e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif Sterol-sensing PF12349.8 AMK76190.1 - 0.1 12.4 6.9 0.19 11.6 6.9 1.5 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation MadM PF03818.13 AMK76190.1 - 0.11 12.4 8.9 3.8 7.5 0.2 3.5 2 1 0 2 2 2 0 Malonate/sodium symporter MadM subunit S_4TM PF18159.1 AMK76190.1 - 0.33 10.2 1.5 0.61 9.3 1.5 1.5 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain MMPL PF03176.15 AMK76190.1 - 0.95 8.3 7.7 1.3 7.9 7.7 1.4 1 1 0 1 1 1 0 MMPL family Pyr_redox_2 PF07992.14 AMK76191.1 - 6.5e-05 22.3 0.0 0.00048 19.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 AMK76191.1 - 0.0011 18.8 4.8 0.02 14.6 4.8 2.3 1 1 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer2 PF00111.27 AMK76191.1 - 0.039 13.9 0.6 0.098 12.6 0.6 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain CitMHS PF03600.16 AMK76192.1 - 3.7e-49 167.5 24.4 3.7e-49 167.5 24.4 1.6 2 0 0 2 2 2 1 Citrate transporter CSD PF00313.22 AMK76193.1 - 4.9e-29 100.0 1.6 5.3e-29 99.9 1.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AMK76193.1 - 0.00097 18.8 1.3 0.0016 18.0 1.3 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.23 AMK76193.1 - 0.008 16.5 0.2 0.01 16.2 0.2 1.1 1 0 0 1 1 1 1 S1 RNA binding domain YrzO PF14142.6 AMK76193.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 YrzO-like protein Radical_SAM PF04055.21 AMK76194.1 - 1.6e-30 106.7 0.0 9.2e-30 104.2 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 AMK76194.1 - 9.5e-22 76.9 2.4 2.2e-21 75.8 2.4 1.7 1 0 0 1 1 1 1 TRAM domain UPF0004 PF00919.20 AMK76194.1 - 1.1e-20 73.5 0.0 2.3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AMK76194.1 - 9.2e-06 25.6 0.3 2.4e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 TRAM domain Amidohydro_2 PF04909.14 AMK76194.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Lipid_DES PF08557.10 AMK76194.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) DsrC PF04358.13 AMK76195.1 - 7.5e-37 126.1 0.0 8.2e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein DsrH PF04077.12 AMK76196.1 - 2e-13 50.3 0.2 2.5e-13 50.0 0.2 1.1 1 0 0 1 1 1 1 DsrH like protein Multi_Drug_Res PF00893.19 AMK76197.1 - 5.9e-29 100.6 6.7 5.9e-29 100.6 6.7 1.3 2 0 0 2 2 2 1 Small Multidrug Resistance protein EamA PF00892.20 AMK76197.1 - 0.00017 21.7 10.3 0.00022 21.4 10.3 1.2 1 0 0 1 1 1 1 EamA-like transporter family Oxidored_q3 PF00499.20 AMK76197.1 - 0.01 15.6 3.2 0.012 15.4 3.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF5381 PF17353.2 AMK76197.1 - 0.038 13.7 5.0 0.032 14.0 2.9 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5381) SHR3_chaperone PF08229.11 AMK76197.1 - 0.041 12.8 0.3 0.047 12.7 0.3 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2569 PF10754.9 AMK76197.1 - 0.12 12.9 5.3 0.18 12.3 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF4064 PF13273.6 AMK76197.1 - 1.9 8.8 10.3 6.1 7.2 10.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF202 PF02656.15 AMK76197.1 - 3.1 8.3 7.7 9 6.8 7.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) YcgR PF07317.12 AMK76198.1 - 6.5e-28 96.7 0.0 1.2e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Flagellar regulator YcgR PilZ PF07238.14 AMK76198.1 - 1.6e-07 31.6 0.0 3.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 PilZ domain TRCF PF03461.15 AMK76199.1 - 8e-28 96.7 0.4 2.5e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 TRCF domain CarD_CdnL_TRCF PF02559.16 AMK76199.1 - 1.1e-22 80.5 0.0 3.9e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 CarD-like/TRCF domain UvrB_inter PF17757.1 AMK76199.1 - 1.7e-21 76.2 0.0 3.9e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 AMK76199.1 - 9.3e-20 71.1 0.2 1.9e-19 70.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK76199.1 - 9e-17 61.4 0.5 9.4e-15 54.9 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AMK76199.1 - 1.1e-11 45.0 0.0 3.9e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AMK76199.1 - 0.0041 16.9 0.0 0.26 11.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 AMK76199.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Glyco_tran_WecB PF03808.13 AMK76199.1 - 0.045 13.7 0.1 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family UB2H PF14814.6 AMK76199.1 - 0.053 13.5 0.0 0.053 13.5 0.0 2.4 3 1 0 3 3 2 0 Bifunctional transglycosylase second domain AroM PF07302.11 AMK76199.1 - 0.058 12.8 0.2 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 AroM protein AAA_22 PF13401.6 AMK76199.1 - 0.072 13.4 0.4 2.1 8.6 0.3 3.1 2 1 0 2 2 2 0 AAA domain Uma2 PF05685.12 AMK76201.1 - 9.5e-34 116.4 0.0 1.1e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Metalloenzyme PF01676.18 AMK76202.1 - 2.7e-73 246.4 0.0 3.1e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 AMK76202.1 - 1.8e-64 217.2 0.0 2.4e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) PglZ PF08665.12 AMK76202.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 PglZ domain Alk_phosphatase PF00245.20 AMK76202.1 - 0.0032 16.5 0.0 0.93 8.4 0.0 2.2 2 0 0 2 2 2 2 Alkaline phosphatase DUF3659 PF12396.8 AMK76202.1 - 0.069 13.1 0.3 0.86 9.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) Peripla_BP_2 PF01497.18 AMK76203.1 - 3e-43 148.1 0.0 3.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein DUF805 PF05656.14 AMK76205.1 - 1.1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF805) Sugar_tr PF00083.24 AMK76205.1 - 0.032 13.1 1.3 0.04 12.8 1.3 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Prominin PF05478.11 AMK76205.1 - 0.49 8.3 3.4 0.61 8.0 3.4 1.0 1 0 0 1 1 1 0 Prominin DUF4282 PF14110.6 AMK76205.1 - 4.4 8.1 7.1 0.37 11.5 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Metallophos PF00149.28 AMK76206.1 - 0.0024 18.4 0.0 0.0036 17.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAIM1 PF06905.13 AMK76206.1 - 0.15 11.8 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Pentapeptide PF00805.22 AMK76207.1 - 1.3e-37 127.0 35.4 2.7e-10 39.7 1.4 5.2 4 1 1 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AMK76207.1 - 2.9e-24 85.0 1.9 1.8e-07 31.2 0.1 4.1 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AMK76207.1 - 2.2e-22 78.9 9.6 1.8e-06 28.0 0.3 5.7 1 1 5 6 6 6 6 Pentapeptide repeats (9 copies) MCPsignal PF00015.21 AMK76208.1 - 2.6e-43 147.8 28.4 2.6e-43 147.8 28.4 4.1 4 1 2 6 6 6 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AMK76208.1 - 2.6e-07 30.9 3.3 3.9e-06 27.2 0.0 4.0 4 0 0 4 4 4 1 HAMP domain Laminin_II PF06009.12 AMK76208.1 - 0.012 15.6 10.4 0.012 15.6 10.4 5.4 5 3 1 6 6 6 0 Laminin Domain II MIP-T3_C PF17749.1 AMK76208.1 - 0.7 9.9 28.8 1.6 8.7 0.7 5.4 3 2 2 5 5 5 0 Microtubule-binding protein MIP-T3 C-terminal region ATPase_2 PF01637.18 AMK76208.1 - 4 7.3 6.3 8.1 6.3 2.6 3.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2524 PF10732.9 AMK76208.1 - 7.1 7.0 16.6 4 7.8 1.7 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) Bac_globin PF01152.21 AMK76209.1 - 1.4e-19 70.4 0.0 1.7e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 AMK76209.1 - 0.004 17.1 0.1 0.014 15.3 0.1 1.8 1 1 0 1 1 1 1 Protoglobin tRNA-synt_2b PF00587.25 AMK76210.1 - 9.2e-33 113.7 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AMK76210.1 - 2.1e-27 95.5 2.3 3.7e-27 94.7 2.3 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4110 PF13422.6 AMK76210.1 - 0.01 15.9 0.8 0.021 14.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) BLOC1_2 PF10046.9 AMK76210.1 - 0.021 15.1 1.6 0.052 13.8 1.6 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 AMK76210.1 - 1.2 9.6 5.7 2.6 8.5 3.9 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CRCB PF02537.15 AMK76211.1 - 9.4e-25 86.8 25.3 9.9e-23 80.3 11.8 2.1 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) AGTRAP PF06396.11 AMK76211.1 - 3.3 7.5 5.8 1.2 8.9 2.9 1.8 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Vma12 PF11712.8 AMK76211.1 - 8.9 6.4 5.4 5.9 7.0 1.6 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RNase_T PF00929.24 AMK76212.1 - 1.9e-35 122.9 0.0 2.1e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 AMK76212.1 - 4.6e-06 26.7 0.1 5.9e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Peptidase_M48_N PF16491.5 AMK76213.1 - 7.4e-55 185.7 11.6 3e-54 183.7 6.3 2.2 2 0 0 2 2 2 2 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 AMK76213.1 - 1.2e-40 139.4 0.0 1.8e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AMK76213.1 - 0.0011 18.2 4.4 0.0048 16.1 1.3 2.8 2 1 1 3 3 3 1 BlaR1 peptidase M56 SprT-like PF10263.9 AMK76213.1 - 0.016 15.0 0.1 0.041 13.8 0.1 1.5 1 1 0 1 1 1 0 SprT-like family DUF2268 PF10026.9 AMK76213.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M78 PF06114.13 AMK76213.1 - 0.079 12.9 0.7 0.13 12.2 0.1 1.6 2 0 0 2 2 2 0 IrrE N-terminal-like domain 2TM PF13239.6 AMK76213.1 - 0.27 11.6 14.1 4.1 7.8 0.1 3.5 3 0 0 3 3 3 0 2TM domain RsgA_GTPase PF03193.16 AMK76214.1 - 1.1e-47 162.1 0.0 1.6e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AMK76214.1 - 5e-06 26.6 0.0 8.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 AMK76214.1 - 0.01 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 AMK76214.1 - 0.032 13.8 0.0 3.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Ras family Guanylate_kin PF00625.21 AMK76214.1 - 0.16 11.7 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Guanylate kinase PduV-EutP PF10662.9 AMK76214.1 - 0.19 11.5 0.0 6.3 6.5 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 AMK76214.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 AMK76214.1 - 0.21 11.1 0.2 0.41 10.1 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region E1_dh PF00676.20 AMK76215.1 - 1.9e-36 125.6 0.0 2.6e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 AMK76215.1 - 1.6e-34 119.1 0.0 1.4e-33 116.1 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AMK76215.1 - 3.1e-18 65.8 0.0 1.2e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AMK76215.1 - 3.1e-10 39.7 0.3 5.4e-10 38.9 0.3 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 AMK76215.1 - 0.0011 18.8 3.8 0.0013 18.6 1.6 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 AMK76215.1 - 0.0016 17.5 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain PFOR_II PF17147.4 AMK76215.1 - 0.0043 17.3 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 AMK76216.1 - 5.1e-17 62.1 0.1 2e-16 60.2 0.1 1.8 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AMK76216.1 - 2.3e-12 46.5 1.3 5.9e-12 45.2 1.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AMK76216.1 - 0.004 16.9 1.1 0.031 14.1 0.5 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 AMK76216.1 - 0.0042 17.8 0.2 0.079 13.7 0.3 2.5 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 AMK76216.1 - 0.04 13.8 0.2 0.079 12.8 0.2 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein PP-binding PF00550.25 AMK76217.1 - 0.0007 19.9 0.2 0.00083 19.7 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site LPD23 PF18838.1 AMK76217.1 - 0.059 13.1 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 HIT PF01230.23 AMK76220.1 - 1.1e-27 96.6 0.0 1.2e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AMK76220.1 - 6.1e-21 75.0 0.0 7.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 AMK76220.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Toprim_4 PF13662.6 AMK76221.1 - 3.2e-23 82.0 0.0 4.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 AMK76221.1 - 1.6e-12 46.8 0.6 2.6e-12 46.1 0.6 1.4 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AMK76221.1 - 5.4e-06 26.6 0.0 9.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Toprim domain HHH PF00633.23 AMK76221.1 - 0.043 13.7 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 AMK76221.1 - 0.095 13.3 0.0 0.47 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain YbaB_DNA_bd PF02575.16 AMK76222.1 - 1.1e-33 115.3 5.8 1.2e-33 115.1 5.8 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DNA_pol3_delta2 PF13177.6 AMK76223.1 - 8.3e-43 146.0 0.0 1.4e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 AMK76223.1 - 6.7e-26 90.9 1.3 1.7e-25 89.6 1.3 1.7 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_tau_5 PF12170.8 AMK76223.1 - 1e-16 61.3 0.0 2e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III tau subunit V interacting with alpha AAA PF00004.29 AMK76223.1 - 5.2e-11 43.1 0.0 1.4e-10 41.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AMK76223.1 - 2.9e-06 27.1 0.0 6.4e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 AMK76223.1 - 1e-05 25.6 0.0 3.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AMK76223.1 - 1.9e-05 25.2 0.0 0.00011 22.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK76223.1 - 7.1e-05 23.2 3.5 0.0005 20.5 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AMK76223.1 - 0.00012 22.4 0.0 0.00062 20.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 AMK76223.1 - 0.00058 19.9 0.1 0.8 9.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AMK76223.1 - 0.00076 19.5 0.0 0.0028 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AMK76223.1 - 0.00082 19.1 0.0 0.0045 16.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AMK76223.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 AMK76223.1 - 0.0079 16.5 0.7 0.53 10.7 0.0 2.8 1 1 1 2 2 2 1 AAA C-terminal domain AAA_24 PF13479.6 AMK76223.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 AMK76223.1 - 0.009 15.2 0.0 2.5 7.2 0.0 2.3 1 1 0 2 2 2 2 TIP49 P-loop domain T2SSE PF00437.20 AMK76223.1 - 0.011 14.8 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 AMK76223.1 - 0.014 14.9 0.1 0.13 11.7 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AMK76223.1 - 0.028 14.7 0.3 1.2 9.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 AMK76223.1 - 0.035 13.3 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 AMK76223.1 - 0.06 13.3 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 AMK76223.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 AMK76223.1 - 0.085 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase Herpes_Helicase PF02689.14 AMK76223.1 - 0.093 10.6 0.0 0.14 10.0 0.0 1.2 1 0 0 1 1 1 0 Helicase AAA_28 PF13521.6 AMK76223.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AMK76223.1 - 0.12 11.7 0.0 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Peptidase_S49 PF01343.18 AMK76224.1 - 9e-36 123.1 0.0 1.5e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 AMK76224.1 - 1.1e-05 25.4 0.2 2.3e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.16 AMK76224.1 - 0.0059 15.6 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase HAD_2 PF13419.6 AMK76225.1 - 5.2e-33 114.6 0.0 6e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK76225.1 - 4.6e-20 72.8 0.1 4e-18 66.5 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AMK76225.1 - 4.8e-13 49.0 0.0 3e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 AMK76225.1 - 4.1e-11 43.6 0.0 5.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK76225.1 - 8.8e-05 22.4 0.1 0.79 9.4 0.0 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AMK76225.1 - 0.011 15.8 0.1 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 AMK76225.1 - 0.11 12.0 0.1 0.43 10.1 0.0 1.9 2 1 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PseudoU_synth_2 PF00849.22 AMK76226.1 - 1.6e-29 103.1 0.0 2.7e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AMK76226.1 - 4.1e-08 32.8 0.8 7.1e-08 32.1 0.8 1.4 1 0 0 1 1 1 1 S4 domain RNase_E_G PF10150.9 AMK76227.1 - 7.1e-93 310.9 0.3 9.9e-93 310.4 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 AMK76227.1 - 1.7e-10 41.1 0.1 3.2e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DnaJ_CXXCXGXG PF00684.19 AMK76227.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaJ central domain CN_hydrolase PF00795.22 AMK76228.1 - 6.5e-55 186.3 0.0 7.5e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAD_porph PF04371.15 AMK76229.1 - 1.4e-107 359.6 0.0 1.6e-107 359.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 AMK76229.1 - 0.048 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Amidinotransferase TPR_11 PF13414.6 AMK76231.1 - 1.7e-37 126.8 13.0 1.1e-08 34.6 2.3 8.0 4 2 4 8 8 8 7 TPR repeat TPR_2 PF07719.17 AMK76231.1 - 1.2e-36 121.8 17.0 3.3e-05 23.7 0.0 8.5 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 AMK76231.1 - 1.1e-26 91.5 7.3 1.6e-05 24.5 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 AMK76231.1 - 5.9e-23 81.2 35.8 1.3e-08 35.3 7.0 5.8 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_19 PF14559.6 AMK76231.1 - 9.8e-22 77.2 29.1 2.4e-07 31.2 4.1 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 AMK76231.1 - 2.1e-21 74.8 36.5 0.00011 22.7 0.3 8.9 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 AMK76231.1 - 3.6e-21 74.0 13.3 0.0014 18.9 0.5 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 AMK76231.1 - 4.6e-17 60.7 0.1 0.18 12.1 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 AMK76231.1 - 1.6e-13 50.6 34.0 3.5e-06 27.1 0.6 5.6 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 AMK76231.1 - 1.6e-12 47.5 34.1 5.7e-05 23.3 0.3 7.1 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_4 PF07721.14 AMK76231.1 - 2.8e-07 30.5 37.2 0.91 10.3 0.2 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 AMK76231.1 - 5.1e-07 29.3 22.5 0.16 12.0 0.4 7.5 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 AMK76231.1 - 3.1e-05 23.7 36.8 0.003 17.4 0.2 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.6 AMK76231.1 - 0.00023 21.4 25.7 0.00081 19.7 4.6 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK76231.1 - 0.00027 21.1 13.2 0.29 11.4 0.4 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AMK76231.1 - 0.0012 19.3 18.6 0.28 11.6 3.2 3.8 1 1 3 4 4 4 2 Bacterial transcriptional activator domain TPR_15 PF13429.6 AMK76231.1 - 0.0043 16.3 17.8 0.04 13.1 0.9 3.6 1 1 2 4 4 4 2 Tetratricopeptide repeat FAT PF02259.23 AMK76231.1 - 0.031 13.5 2.9 0.28 10.3 0.1 2.9 1 1 1 4 4 4 0 FAT domain MIT PF04212.18 AMK76231.1 - 0.045 13.8 5.4 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF5112 PF17139.4 AMK76231.1 - 0.097 12.1 0.9 0.81 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5112) Wzy_C_2 PF11846.8 AMK76231.1 - 0.86 9.5 6.1 4.4 7.2 1.2 3.3 3 2 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal HemY_N PF07219.13 AMK76231.1 - 0.87 9.8 8.8 12 6.1 2.2 3.5 2 2 2 4 4 4 0 HemY protein N-terminus TPR_6 PF13174.6 AMK76231.1 - 2.9 8.7 16.6 84 4.1 0.3 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 AMK76231.1 - 6 6.5 19.1 6.5 6.4 1.3 4.5 1 1 2 4 4 4 0 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 AMK76231.1 - 8.9 6.0 12.5 1 9.0 0.9 3.7 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4157 PF13699.6 AMK76232.1 - 7.9e-31 106.1 0.1 7.9e-31 106.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4157) Peripla_BP_3 PF13377.6 AMK76232.1 - 0.014 15.8 0.5 0.033 14.5 0.5 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain PagL PF09411.10 AMK76232.1 - 0.04 14.1 0.7 4.6 7.4 0.1 2.9 2 1 1 3 3 3 0 Lipid A 3-O-deacylase (PagL) AAA PF00004.29 AMK76233.1 - 4.4e-24 85.4 0.0 1.5e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK76233.1 - 0.001 19.1 0.2 0.47 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK76233.1 - 0.0042 17.5 11.9 0.05 14.0 0.3 3.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 AMK76233.1 - 0.008 16.3 0.4 0.051 13.7 0.0 2.5 2 2 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AMK76233.1 - 0.03 14.0 0.1 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 AMK76233.1 - 0.032 14.5 3.2 2.3 8.5 0.0 3.6 4 1 1 5 5 5 0 AAA domain ABC_tran PF00005.27 AMK76233.1 - 0.066 13.7 0.1 6.8 7.2 0.0 3.3 2 1 0 2 2 2 0 ABC transporter DUF3120 PF11318.8 AMK76233.1 - 0.076 13.4 0.5 0.4 11.0 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3120) TsaE PF02367.17 AMK76233.1 - 0.11 12.5 0.2 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF927 PF06048.11 AMK76233.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) TIP49 PF06068.13 AMK76233.1 - 0.16 11.1 0.2 7 5.7 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Tail_P2_I PF09684.10 AMK76238.1 - 4.5e-09 36.4 0.1 8.7e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) Baseplate_J PF04865.14 AMK76239.1 - 4.6e-12 45.6 0.0 8.5e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Baseplate J-like protein GPW_gp25 PF04965.14 AMK76240.1 - 3.5e-18 65.1 0.3 4.1e-18 64.9 0.3 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme DUF3540 PF12059.8 AMK76242.1 - 0.07 13.0 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) Phage_GPD PF05954.11 AMK76243.1 - 2.5e-16 59.8 0.0 4e-16 59.2 0.0 1.3 1 1 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_P2_GpU PF06995.11 AMK76245.1 - 0.0032 17.1 0.0 0.66 9.6 0.0 2.6 3 0 0 3 3 3 2 Phage P2 GpU Phage_T4_gp19 PF06841.12 AMK76246.1 - 1e-28 99.9 0.0 1.3e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 T4-like virus tail tube protein gp19 Phage_T4_gp19 PF06841.12 AMK76248.1 - 2.8e-30 104.9 0.0 3.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 T4-like virus tail tube protein gp19 Phage_sheath_1 PF04984.14 AMK76249.1 - 3.1e-27 95.5 0.1 1.6e-26 93.1 0.0 2.2 3 0 0 3 3 3 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 AMK76249.1 - 2e-14 53.4 0.0 3.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain DUF4255 PF14065.6 AMK76251.1 - 1.8e-28 99.4 0.4 2.2e-28 99.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4255) FA_hydroxylase PF04116.13 AMK76252.1 - 4.9e-07 30.2 14.9 7.7e-07 29.5 14.9 1.3 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF4913 PF16259.5 AMK76252.1 - 0.03 14.4 6.2 0.13 12.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) ABC_tran PF00005.27 AMK76253.1 - 2.4e-30 105.9 0.0 4.4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK76253.1 - 6.1e-12 46.0 2.7 8.2e-07 29.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK76253.1 - 1.5e-05 25.6 0.2 2.8e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AMK76253.1 - 0.0001 22.1 0.0 0.0078 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF4162 PF13732.6 AMK76253.1 - 0.00021 21.9 0.0 0.0005 20.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 AMK76253.1 - 0.00045 19.7 0.1 0.38 10.2 0.2 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 AMK76253.1 - 0.00083 19.8 0.1 0.0089 16.5 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AMK76253.1 - 0.0012 18.6 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 AMK76253.1 - 0.0035 17.1 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 AMK76253.1 - 0.0068 16.4 0.0 0.018 15.1 0.0 1.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 AMK76253.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AMK76253.1 - 0.02 14.6 0.3 0.093 12.4 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 AMK76253.1 - 0.035 14.5 0.0 0.085 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Amidinotransf PF02274.17 AMK76253.1 - 0.095 11.8 0.1 8.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Amidinotransferase Hydrolase PF00702.26 AMK76253.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF72 PF01904.18 AMK76253.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF72 Zn_peptidase PF04228.13 AMK76253.1 - 0.15 11.5 0.0 6.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase ABC2_membrane PF01061.24 AMK76254.1 - 2.9e-32 111.8 23.0 2.9e-32 111.8 23.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AMK76254.1 - 0.0012 18.0 28.8 0.0012 18.0 28.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein PAS_3 PF08447.12 AMK76255.1 - 3.6e-65 216.3 8.3 3.7e-22 78.4 0.1 4.9 4 0 0 4 4 4 4 PAS fold Response_reg PF00072.24 AMK76255.1 - 1.8e-55 185.9 0.4 2.8e-27 95.1 0.0 3.9 5 0 0 5 5 5 2 Response regulator receiver domain HATPase_c PF02518.26 AMK76255.1 - 2.7e-54 182.5 0.1 2.2e-26 92.5 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AMK76255.1 - 1.2e-48 164.0 2.9 3.1e-13 49.9 0.2 5.7 5 0 0 5 5 5 4 PAS fold PAS_9 PF13426.7 AMK76255.1 - 3.2e-37 126.9 0.0 4.6e-10 39.7 0.0 5.6 5 0 0 5 5 5 5 PAS domain PAS PF00989.25 AMK76255.1 - 7.6e-37 125.8 0.2 1e-11 44.8 0.1 5.6 5 0 0 5 5 5 5 PAS fold HisKA PF00512.25 AMK76255.1 - 1.6e-35 120.9 0.9 3.2e-18 65.5 0.1 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AMK76255.1 - 9.9e-15 54.2 1.7 0.00062 19.7 0.0 5.7 5 0 0 5 5 5 3 PAS domain Hpt PF01627.23 AMK76255.1 - 9.2e-10 38.7 3.1 9.2e-10 38.7 3.1 3.1 3 0 0 3 3 3 1 Hpt domain HATPase_c_3 PF13589.6 AMK76255.1 - 2.1e-06 27.6 0.0 0.043 13.7 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK76255.1 - 1.2e-05 25.3 0.2 0.17 11.9 0.0 3.4 3 0 0 3 3 3 2 Histidine kinase-like ATPase domain PAS_11 PF14598.6 AMK76255.1 - 2.4e-05 24.4 0.8 5.3 7.2 0.0 3.6 3 0 0 3 3 3 3 PAS domain SLT PF01464.20 AMK76256.1 - 8.1e-12 44.8 0.0 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain FtsX PF02687.21 AMK76256.1 - 0.97 10.0 6.2 2.2 8.8 6.2 1.5 1 0 0 1 1 1 0 FtsX-like permease family BatA PF07584.11 AMK76256.1 - 1.5 9.3 6.7 1.2 9.6 0.2 2.9 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal RskA PF10099.9 AMK76256.1 - 8.3 6.7 7.8 26 5.1 7.8 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Abhydrolase_1 PF00561.20 AMK76257.1 - 8.4e-17 61.7 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK76257.1 - 1.9e-09 38.5 0.3 3.1e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK76257.1 - 6e-09 35.5 0.2 1.2e-07 31.2 0.2 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1801 PF08818.11 AMK76258.1 - 1.4e-09 38.3 0.0 1.7e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) LMWPc PF01451.21 AMK76260.1 - 4.1e-06 27.2 0.0 5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Mob_synth_C PF06463.13 AMK76261.1 - 1.3e-37 128.6 0.0 2.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AMK76261.1 - 9.3e-27 94.4 0.1 1.3e-26 94.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AMK76261.1 - 1.3e-07 32.0 0.0 2.7e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AMK76261.1 - 0.002 18.3 0.1 0.0094 16.1 0.0 2.1 2 1 0 2 2 2 1 4Fe-4S single cluster domain HNH PF01844.23 AMK76262.1 - 7.2e-11 42.1 11.2 1.3e-10 41.3 11.2 1.4 1 0 0 1 1 1 1 HNH endonuclease Ima1_N PF09779.9 AMK76262.1 - 0.014 16.2 1.4 1.5 9.7 0.4 2.1 2 0 0 2 2 2 0 Ima1 N-terminal domain Endonuclease_7 PF02945.15 AMK76262.1 - 0.048 13.6 2.8 0.07 13.1 2.8 1.3 1 0 0 1 1 1 0 Recombination endonuclease VII Adenine_glyco PF03352.13 AMK76263.1 - 1.5e-77 259.3 0.1 1.7e-77 259.2 0.1 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Putative_PNPOx PF01243.20 AMK76264.1 - 5.5e-10 39.3 0.0 7.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EAL PF00563.20 AMK76265.1 - 9.2e-73 244.7 0.8 2.2e-72 243.4 0.2 2.0 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK76265.1 - 6.8e-52 175.5 0.0 1.5e-51 174.4 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE PF03924.13 AMK76265.1 - 1.2e-33 116.7 0.1 2.8e-33 115.4 0.1 1.6 1 0 0 1 1 1 1 CHASE domain MASE1 PF05231.14 AMK76265.1 - 1.1e-25 90.5 21.1 1.7e-25 89.8 21.1 1.3 1 0 0 1 1 1 1 MASE1 PAS_9 PF13426.7 AMK76265.1 - 9.5e-19 67.6 0.0 4.2e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK76265.1 - 3.9e-11 42.9 0.1 1.1e-10 41.5 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK76265.1 - 3e-08 33.9 0.0 1e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AMK76265.1 - 1.9e-07 31.3 0.1 9.7e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AMK76265.1 - 7.8e-05 22.6 0.0 0.0011 19.0 0.0 2.8 2 0 0 2 2 2 1 PAS domain NMT1 PF09084.11 AMK76266.1 - 4.6e-13 49.6 0.0 1.7e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AMK76266.1 - 2.6e-08 33.8 0.0 5.6e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AMK76266.1 - 4.9e-08 32.7 0.0 7.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 AMK76266.1 - 3.3e-05 23.7 0.1 0.21 11.2 0.1 2.1 2 0 0 2 2 2 2 NMT1-like family OpuAC PF04069.12 AMK76266.1 - 0.00096 18.8 1.8 0.061 12.9 0.1 2.5 1 1 1 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 AMK76267.1 - 6.7e-21 74.8 7.5 6.7e-21 74.8 7.5 2.0 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AMK76268.1 - 9.3e-27 94.2 0.0 1.5e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK76268.1 - 3.9e-08 33.5 0.3 0.00059 19.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AMK76268.1 - 1.4e-05 25.1 0.1 2.9e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AMK76268.1 - 6.1e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AMK76268.1 - 0.00069 19.9 0.0 0.0015 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AMK76268.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AMK76268.1 - 0.0017 18.1 0.1 0.0057 16.4 0.0 1.9 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 AMK76268.1 - 0.0018 18.7 0.1 0.0075 16.7 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 AMK76268.1 - 0.0019 18.5 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AMK76268.1 - 0.0043 17.0 0.1 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 AMK76268.1 - 0.0076 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 AMK76268.1 - 0.011 15.6 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 AMK76268.1 - 0.012 16.1 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AMK76268.1 - 0.016 14.9 0.0 1.6 8.4 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 AMK76268.1 - 0.017 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TniB PF05621.11 AMK76268.1 - 0.023 14.1 0.1 0.96 8.8 0.1 2.1 1 1 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 AMK76268.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AMK76268.1 - 0.031 13.5 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 AMK76268.1 - 0.042 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 AMK76268.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 AMK76268.1 - 0.046 14.1 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 AMK76268.1 - 0.076 13.6 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AMK76268.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AMK76268.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AMK76268.1 - 0.12 12.7 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 AMK76268.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 AMK76268.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 AMK76268.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 AMK76268.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 AMK76268.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AMK76268.1 - 0.2 11.3 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 AMK76268.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UPF0029 PF01205.19 AMK76269.1 - 1.6e-28 99.1 0.0 2.1e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 AMK76269.1 - 2.4e-08 33.7 0.0 5.2e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) DsrH PF04077.12 AMK76269.1 - 0.025 14.7 0.1 0.07 13.3 0.0 1.8 2 0 0 2 2 2 0 DsrH like protein TerB PF05099.13 AMK76270.1 - 2.6e-21 76.1 0.3 2.6e-21 76.1 0.3 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TerB DnaJ PF00226.31 AMK76270.1 - 1.5e-13 50.6 0.2 3.9e-13 49.3 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF533 PF04391.12 AMK76270.1 - 2.8e-05 23.8 2.2 0.043 13.4 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF533) RPT PF13446.6 AMK76270.1 - 0.016 15.2 0.1 0.037 14.0 0.1 1.8 1 1 0 1 1 1 0 A repeated domain in UCH-protein SLIDE PF09111.10 AMK76270.1 - 0.094 12.7 1.2 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 SLIDE SAICAR_synt PF01259.18 AMK76271.1 - 4.2e-102 341.1 0.0 4.9e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase BNR_2 PF13088.6 AMK76272.1 - 2.1e-08 33.8 0.1 0.0007 19.0 0.0 2.4 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 AMK76272.1 - 7e-06 25.3 9.3 1.1 9.5 0.4 5.9 5 0 0 5 5 5 3 BNR/Asp-box repeat PEX-2N PF09263.10 AMK76272.1 - 0.0052 17.1 0.4 19 5.7 0.0 4.3 4 0 0 4 4 4 1 Peroxisome biogenesis factor 1, N-terminal TonB_dep_Rec PF00593.24 AMK76273.1 - 1.5e-49 170.2 45.2 1.5e-49 170.2 45.2 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK76273.1 - 9.8e-16 58.3 3.7 4.1e-15 56.3 0.1 3.2 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain Glyco_tranf_2_3 PF13641.6 AMK76274.1 - 1e-29 104.1 0.0 1.6e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AMK76274.1 - 6.7e-26 91.1 0.2 6.1e-25 88.0 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AMK76274.1 - 1e-23 84.3 0.6 1e-23 84.3 0.6 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AMK76274.1 - 4.2e-12 45.9 0.0 9.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_17 PF00332.18 AMK76274.1 - 7.6e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Cellulose_synt PF03552.14 AMK76274.1 - 0.0061 15.1 0.2 0.0061 15.1 0.2 2.4 2 1 1 3 3 3 1 Cellulose synthase Chitin_synth_2 PF03142.15 AMK76274.1 - 0.048 12.3 0.0 12 4.3 0.0 2.8 3 0 0 3 3 3 0 Chitin synthase DUF2582 PF10771.9 AMK76275.1 - 1.3e-20 73.3 0.4 1.3e-20 73.3 0.4 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix domain (DUF2582) TBPIP PF07106.13 AMK76275.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 0 TBPIP/Hop2 winged helix domain HTH_36 PF13730.6 AMK76275.1 - 0.044 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_9 PF08221.11 AMK76275.1 - 0.053 13.6 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain CvfB_WH PF17783.1 AMK76275.1 - 0.076 12.8 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 CvfB-like winged helix domain MinE PF03776.14 AMK76276.1 - 6.3e-23 80.6 0.1 7.1e-23 80.4 0.1 1.0 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DNA_pol3_theta PF06440.11 AMK76276.1 - 0.1 12.3 0.9 0.15 11.7 0.3 1.6 1 1 0 1 1 1 0 DNA polymerase III, theta subunit CbiA PF01656.23 AMK76277.1 - 1.9e-19 70.0 0.1 2.6e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AMK76277.1 - 2.4e-19 69.9 0.1 5.3e-19 68.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 AMK76277.1 - 1.2e-16 60.9 0.7 2.1e-15 56.9 0.7 2.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AMK76277.1 - 3.7e-10 39.5 0.6 7.7e-10 38.5 0.6 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AMK76277.1 - 1.6e-09 37.4 1.4 7.1e-09 35.3 0.9 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AMK76277.1 - 8.7e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AMK76277.1 - 7.4e-05 22.3 0.1 0.001 18.6 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 AMK76277.1 - 7.7e-05 22.5 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 AMK76277.1 - 0.0015 18.4 1.7 0.19 11.6 0.9 2.8 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 AMK76277.1 - 0.002 17.2 0.4 0.0043 16.1 0.4 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AMK76277.1 - 0.0048 16.5 1.8 0.016 14.8 1.8 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 AMK76277.1 - 0.014 15.2 0.1 0.035 13.9 0.1 1.7 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 AMK76277.1 - 0.023 14.6 0.1 0.49 10.3 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase VirC1 PF07015.11 AMK76277.1 - 0.033 13.5 0.2 0.057 12.7 0.2 1.3 1 0 0 1 1 1 0 VirC1 protein NACHT PF05729.12 AMK76277.1 - 0.18 11.7 0.7 0.35 10.8 0.7 1.6 1 1 0 1 1 1 0 NACHT domain MinC_C PF03775.16 AMK76278.1 - 5.3e-33 113.1 0.2 9.4e-33 112.2 0.2 1.4 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain MinC_N PF05209.13 AMK76278.1 - 5.5e-20 71.2 0.1 9.6e-20 70.5 0.1 1.3 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain FapA PF03961.13 AMK76278.1 - 0.00022 20.0 0.0 0.00032 19.5 0.0 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF2807 PF10988.8 AMK76278.1 - 0.058 13.2 1.0 0.094 12.5 0.3 1.7 2 0 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Lsr2 PF11774.8 AMK76278.1 - 0.16 12.1 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Lsr2 MgtE PF01769.16 AMK76279.1 - 1.2e-24 87.0 12.6 1.2e-24 87.0 12.6 1.9 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 AMK76279.1 - 3.9e-19 69.1 0.0 1.1e-18 67.6 0.0 1.9 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 AMK76279.1 - 1.3e-07 31.9 2.1 0.0027 18.1 0.2 2.7 2 0 0 2 2 2 2 CBS domain DUF1241 PF06840.11 AMK76279.1 - 0.0036 17.0 0.0 0.0096 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) ATP_bind_2 PF03668.15 AMK76280.1 - 4.7e-95 318.1 0.0 5.2e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_33 PF13671.6 AMK76280.1 - 0.0048 17.1 0.3 0.69 10.1 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 AMK76280.1 - 0.02 15.4 0.2 0.19 12.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain Ribosomal_S30AE PF02482.19 AMK76281.1 - 9.9e-26 90.4 6.8 1.1e-25 90.2 6.8 1.0 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein MOEP19 PF16005.5 AMK76281.1 - 0.081 12.9 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 KH-like RNA-binding domain DUF5496 PF17600.2 AMK76281.1 - 0.081 13.0 0.1 0.3 11.2 0.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5496) DUF1664 PF07889.12 AMK76281.1 - 0.11 12.6 3.9 0.12 12.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.9 AMK76281.1 - 0.44 10.8 3.4 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Sigma54_DBD PF04552.13 AMK76282.1 - 8.6e-69 230.3 0.1 1.4e-68 229.7 0.1 1.3 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 AMK76282.1 - 2.4e-55 187.2 1.0 3.3e-55 186.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 AMK76282.1 - 3.6e-16 58.7 15.6 9.6e-16 57.4 15.6 1.8 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) HTH_38 PF13936.6 AMK76282.1 - 0.036 13.8 0.5 0.17 11.7 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain YabA PF06156.13 AMK76282.1 - 0.24 12.1 3.4 0.72 10.5 3.4 1.8 1 0 0 1 1 1 0 Initiation control protein YabA ABC_tran PF00005.27 AMK76283.1 - 6.2e-33 114.2 0.0 1.1e-32 113.4 0.0 1.4 2 0 0 2 2 2 1 ABC transporter BCA_ABC_TP_C PF12399.8 AMK76283.1 - 9.5e-05 22.2 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AMK76283.1 - 0.0032 17.3 5.2 0.18 11.6 0.5 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK76283.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AMK76283.1 - 0.058 12.8 0.0 0.99 8.8 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 AMK76283.1 - 0.097 12.9 0.1 0.6 10.4 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IgG_binding_B PF01378.17 AMK76283.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 B domain OstA PF03968.14 AMK76284.1 - 5.3e-22 78.1 0.2 6.6e-22 77.9 0.2 1.1 1 0 0 1 1 1 1 OstA-like protein LptC PF06835.13 AMK76284.1 - 0.033 13.8 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide-assembly, LptC-related LptC PF06835.13 AMK76285.1 - 1.8e-31 109.1 0.0 2.1e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related GlcNAc-1_reg PF18440.1 AMK76285.1 - 0.017 15.4 0.0 0.066 13.5 0.0 1.9 1 1 1 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain ChlamPMP_M PF07548.11 AMK76285.1 - 0.083 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Hydrolase_3 PF08282.12 AMK76286.1 - 6e-11 42.6 0.0 1.9e-08 34.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK76286.1 - 5.3e-08 33.4 1.1 1.4e-05 25.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AMK76286.1 - 0.00018 21.7 0.9 0.0005 20.2 0.0 2.0 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 AMK76286.1 - 0.16 11.1 0.0 0.61 9.2 0.0 1.8 1 1 0 1 1 1 0 Trehalose-phosphatase HAD PF12710.7 AMK76286.1 - 0.19 12.1 1.1 0.9 9.9 0.1 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase SIS PF01380.22 AMK76287.1 - 2.7e-31 108.1 0.1 5.3e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 AMK76287.1 - 2.7e-17 62.9 1.8 4.1e-08 33.5 0.0 3.5 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 AMK76287.1 - 0.0011 19.1 1.0 0.014 15.4 0.0 2.4 1 1 1 2 2 2 1 SIS domain ABC_tran PF00005.27 AMK76288.1 - 1.6e-29 103.2 0.0 2.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 AMK76288.1 - 6.7e-05 22.9 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AMK76288.1 - 0.00019 21.1 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AMK76288.1 - 0.00022 21.5 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK76288.1 - 0.00033 21.1 0.0 0.00046 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AMK76288.1 - 0.0018 18.3 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 AMK76288.1 - 0.0021 18.6 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 AMK76288.1 - 0.003 16.4 2.4 0.49 9.1 0.6 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 AMK76288.1 - 0.0031 17.1 0.3 0.027 14.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 AMK76288.1 - 0.0064 16.3 0.4 0.025 14.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 AMK76288.1 - 0.0073 16.0 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AMK76288.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 AMK76288.1 - 0.02 14.3 0.3 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 AMK76288.1 - 0.028 14.2 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AMK76288.1 - 0.04 14.0 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AMK76288.1 - 0.063 13.1 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AMK76288.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AMK76288.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 AMK76288.1 - 0.1 11.7 0.3 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase T2SSE PF00437.20 AMK76288.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 AMK76288.1 - 0.13 12.6 0.3 0.18 12.1 0.3 1.3 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 AMK76288.1 - 0.22 10.9 0.1 2.9 7.3 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 AMK76288.1 - 0.3 11.6 0.8 0.6 10.7 0.8 1.6 1 1 0 1 1 1 0 AAA domain MlaE PF02405.16 AMK76289.1 - 1.5e-73 247.0 15.9 1.8e-73 246.7 15.9 1.1 1 0 0 1 1 1 1 Permease MlaE Bac_export_2 PF01312.19 AMK76289.1 - 6.6 5.8 6.5 2.5 7.2 2.0 1.9 1 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family MlaD PF02470.20 AMK76290.1 - 5.4e-24 84.3 0.2 9.7e-24 83.5 0.1 1.5 2 0 0 2 2 2 1 MlaD protein DUF3450 PF11932.8 AMK76290.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) STAS_2 PF13466.6 AMK76291.1 - 5.4e-08 33.1 0.0 6.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AMK76291.1 - 5.2e-05 22.9 0.0 7.3e-05 22.4 0.0 1.2 1 1 0 1 1 1 1 STAS domain EPSP_synthase PF00275.20 AMK76292.1 - 3.5e-114 381.8 2.4 3.9e-114 381.6 2.4 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HisG PF01634.18 AMK76293.1 - 7.4e-49 165.8 0.0 9.2e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Histidinol_dh PF00815.20 AMK76294.1 - 3.1e-164 546.8 2.6 3.8e-164 546.5 2.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Laminin_B PF00052.18 AMK76295.1 - 1.9e-14 53.7 0.0 2.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Laminin B (Domain IV) PEP-CTERM PF07589.11 AMK76295.1 - 0.00068 19.6 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 PEP-CTERM motif Aminotran_1_2 PF00155.21 AMK76298.1 - 6.6e-47 160.4 0.0 7.3e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AMK76298.1 - 0.001 18.5 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 AMK76298.1 - 0.0078 15.0 0.0 0.019 13.7 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.13 AMK76298.1 - 0.031 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Allinase Aminotran_5 PF00266.19 AMK76298.1 - 0.083 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AMK76298.1 - 0.24 9.9 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Rieske PF00355.26 AMK76299.1 - 5.5e-11 42.3 0.0 9.3e-11 41.5 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_Fe-S_N PF10399.9 AMK76299.1 - 9.2e-11 40.9 0.0 1.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cytochrome_B PF00033.19 AMK76300.1 - 3.9e-67 225.7 18.0 3.9e-67 225.7 18.0 2.0 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_C PF00032.17 AMK76300.1 - 6.1e-45 151.7 1.1 6.1e-45 151.7 1.1 3.7 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N_2 PF13631.6 AMK76300.1 - 2e-41 141.8 8.3 2e-41 141.8 8.3 2.0 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF2582 PF10771.9 AMK76301.1 - 3.9e-11 42.9 0.0 6.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix domain (DUF2582) Ndc1_Nup PF09531.10 AMK76301.1 - 1.7 7.3 5.6 1.7 7.2 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GGDEF PF00990.21 AMK76302.1 - 5.4e-43 146.5 0.0 7.4e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain TspO_MBR PF03073.15 AMK76302.1 - 0.66 10.0 9.2 0.35 10.9 6.8 1.7 1 1 0 1 1 1 0 TspO/MBR family DUF1656 PF07869.12 AMK76303.1 - 0.01 15.8 2.3 0.026 14.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) SieB PF14163.6 AMK76303.1 - 0.17 11.4 0.9 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Super-infection exclusion protein B Methyltransf_3 PF01596.17 AMK76304.1 - 7.6e-73 244.2 0.0 8.9e-73 244.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 AMK76304.1 - 2.6e-14 54.1 0.0 4.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76304.1 - 4.8e-05 24.0 0.0 0.00012 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 AMK76304.1 - 6.2e-05 22.8 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 AMK76304.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AMK76304.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK76304.1 - 0.06 14.0 0.0 0.17 12.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76304.1 - 0.088 13.6 0.0 0.19 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 AMK76304.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 AMK76304.1 - 0.2 11.8 0.0 0.26 11.4 0.0 1.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase PsiF_repeat PF07769.14 AMK76305.1 - 1.7e-05 24.6 16.1 0.007 16.2 3.9 2.3 2 0 0 2 2 2 2 psiF repeat TraW_N PF12477.8 AMK76305.1 - 0.094 12.7 0.6 0.19 11.7 0.6 1.6 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal LPAM_1 PF08139.12 AMK76305.1 - 0.58 10.7 4.1 1.3 9.7 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_S24 PF00717.23 AMK76306.1 - 4.9e-12 45.6 0.0 7.3e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like LexA_DNA_bind PF01726.16 AMK76306.1 - 8.8e-11 41.4 0.1 2.1e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 LexA DNA binding domain HTH_20 PF12840.7 AMK76306.1 - 0.12 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CutA1 PF03091.15 AMK76307.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein P-II PF00543.22 AMK76307.1 - 0.12 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II T2SSE PF00437.20 AMK76308.1 - 1.4e-38 132.5 0.0 1.8e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 AMK76308.1 - 0.0014 19.1 0.0 0.0029 18.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 AMK76308.1 - 0.0024 17.2 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 AMK76308.1 - 0.0076 16.0 0.3 0.021 14.6 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AMK76308.1 - 0.0081 16.7 0.1 0.023 15.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK76308.1 - 0.013 15.8 0.0 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 AMK76308.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AMK76308.1 - 0.029 13.9 0.0 0.11 12.0 0.0 1.9 3 0 0 3 3 3 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 AMK76308.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 AMK76308.1 - 0.047 12.6 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AMK76308.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AMK76308.1 - 0.057 13.8 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 AMK76308.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DAP3 PF10236.9 AMK76308.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PAS_4 PF08448.10 AMK76309.1 - 5.1e-43 145.8 0.1 4.1e-15 56.0 0.0 6.4 6 0 0 6 6 6 3 PAS fold PAS_3 PF08447.12 AMK76309.1 - 1.1e-32 112.1 0.4 2.8e-11 43.5 0.1 4.9 5 0 0 5 5 5 4 PAS fold PAS PF00989.25 AMK76309.1 - 2.6e-25 88.6 0.0 4.1e-05 23.6 0.0 6.5 6 0 0 6 6 6 5 PAS fold PAS_9 PF13426.7 AMK76309.1 - 2.4e-19 69.5 0.0 0.00014 22.0 0.0 5.2 5 1 0 5 5 5 4 PAS domain HisKA_3 PF07730.13 AMK76309.1 - 8.4e-15 55.0 2.2 8.4e-15 55.0 2.2 3.8 4 0 0 4 4 4 1 Histidine kinase PAS_8 PF13188.7 AMK76309.1 - 5.3e-10 39.1 0.1 0.026 14.5 0.0 4.6 4 0 0 4 4 4 3 PAS domain HATPase_c PF02518.26 AMK76309.1 - 1.7e-06 28.5 0.0 1.2e-05 25.8 0.0 2.4 2 1 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 AMK76309.1 - 0.0018 18.4 2.5 0.38 10.9 0.0 4.8 5 2 1 6 6 6 1 PAS fold HATPase_c_2 PF13581.6 AMK76309.1 - 0.0024 17.8 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_10 PF13596.6 AMK76309.1 - 0.019 15.6 0.1 0.22 12.1 0.0 2.9 3 0 0 3 3 3 0 PAS domain DUF4916 PF16262.5 AMK76309.1 - 0.066 12.7 0.8 0.99 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) DUF3630 PF12305.8 AMK76309.1 - 0.07 13.2 0.4 3.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3630) GvpL_GvpF PF06386.11 AMK76309.1 - 0.13 12.2 1.8 0.34 10.8 1.8 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Transcrip_act PF04949.13 AMK76309.1 - 0.25 11.2 6.0 0.24 11.3 3.7 2.0 2 0 0 2 2 2 0 Transcriptional activator Response_reg PF00072.24 AMK76310.1 - 6.3e-29 100.4 0.1 8.8e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK76310.1 - 1.4e-18 66.1 0.1 2.4e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 AMK76310.1 - 0.00023 20.6 0.8 0.00037 19.9 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 AMK76310.1 - 0.00085 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 AMK76310.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AMK76310.1 - 0.0059 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AMK76310.1 - 0.02 14.8 0.2 0.055 13.4 0.2 1.8 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 AMK76310.1 - 0.12 12.5 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2089 PF09862.9 AMK76310.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_7 PF02796.15 AMK76310.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Usher PF00577.20 AMK76311.1 - 0.28 10.0 0.0 0.33 9.8 0.0 1.0 1 0 0 1 1 1 0 Outer membrane usher protein EAL PF00563.20 AMK76312.1 - 1.4e-71 240.8 0.2 3.1e-71 239.7 0.2 1.6 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK76312.1 - 1.7e-50 170.9 1.2 3.3e-50 170.0 1.2 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK76312.1 - 1.7e-27 95.7 0.1 9.3e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK76312.1 - 8.9e-24 83.7 0.2 2.2e-11 43.8 0.1 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AMK76312.1 - 4.7e-22 78.3 0.0 2.5e-14 53.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AMK76312.1 - 1.8e-13 50.2 0.0 1.7e-05 24.7 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 AMK76312.1 - 1.4e-08 34.9 0.3 1.8e-06 28.1 0.1 2.5 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 AMK76312.1 - 0.00013 22.1 0.8 1.1 9.4 0.0 4.2 3 2 0 3 3 3 2 PAS fold PAS_12 PF18095.1 AMK76312.1 - 0.035 13.7 0.0 0.91 9.2 0.0 2.3 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain PAS_10 PF13596.6 AMK76312.1 - 0.13 12.8 0.1 20 5.9 0.1 3.2 2 1 0 2 2 2 0 PAS domain TM140 PF14985.6 AMK76312.1 - 0.27 10.8 6.7 0.5 9.9 6.7 1.4 1 0 0 1 1 1 0 TM140 protein family MCPsignal PF00015.21 AMK76313.1 - 9e-47 159.1 41.8 1.2e-45 155.4 26.7 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3365 PF11845.8 AMK76313.1 - 4.6e-31 108.3 7.5 2.7e-30 105.7 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3365) HAMP PF00672.25 AMK76313.1 - 4.1e-06 27.1 0.7 0.00043 20.6 0.0 3.8 4 1 1 5 5 4 1 HAMP domain GARP PF16731.5 AMK76313.1 - 0.0019 17.9 7.6 0.0019 17.9 7.6 3.2 1 1 1 3 3 3 2 Glutamic acid/alanine-rich protein of Trypanosoma Fib_alpha PF08702.10 AMK76313.1 - 0.0078 16.4 16.1 0.57 10.4 3.0 3.2 2 1 0 2 2 2 2 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 AMK76313.1 - 0.24 11.8 16.4 0.14 12.6 1.2 3.9 3 1 0 3 3 3 0 Syntaxin-like protein Stomoxyn PF11585.8 AMK76313.1 - 0.25 11.4 2.6 4.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn Cauli_AT PF03233.13 AMK76313.1 - 0.64 9.9 7.3 2 8.3 0.3 3.2 3 0 0 3 3 3 0 Aphid transmission protein Transcrip_act PF04949.13 AMK76313.1 - 1.6 8.6 6.9 0.9 9.4 0.5 2.9 2 1 1 3 3 3 0 Transcriptional activator TMPIT PF07851.13 AMK76313.1 - 2.1 7.5 10.7 0.49 9.6 1.9 2.5 2 0 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 AMK76313.1 - 2.5 8.1 31.1 3.5 7.6 11.1 3.5 2 2 1 3 3 3 0 Laminin Domain II DUF948 PF06103.11 AMK76313.1 - 3.6 7.9 28.8 0.4 11.0 6.2 4.7 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 AMK76313.1 - 3.7 6.7 19.3 0.1 11.8 7.1 2.4 2 1 0 2 2 2 0 Invariant surface glycoprotein DUF1700 PF08006.11 AMK76313.1 - 3.7 7.0 6.6 1.9 8.0 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) TrbC PF04956.13 AMK76313.1 - 6.7 7.0 7.9 0.92 9.8 0.4 3.1 3 1 0 3 3 3 0 TrbC/VIRB2 family Noelin-1 PF12308.8 AMK76313.1 - 9 6.4 7.5 15 5.6 0.1 3.5 3 2 0 3 3 3 0 Neurogenesis glycoprotein TusA PF01206.17 AMK76314.1 - 2.6e-22 78.4 0.2 2.8e-22 78.3 0.2 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF3348 PF11828.8 AMK76315.1 - 0.058 13.1 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) TOPRIM_C PF16898.5 AMK76315.1 - 2.4 8.4 7.6 1.1 9.5 1.8 2.6 2 2 0 2 2 2 0 C-terminal associated domain of TOPRIM ArgJ PF01960.18 AMK76317.1 - 4.1e-145 483.2 4.5 4.6e-145 483.1 4.5 1.0 1 0 0 1 1 1 1 ArgJ family TMP-TENI PF02581.17 AMK76318.1 - 2.9e-36 124.5 0.0 4.5e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase NUDIX_4 PF14815.6 AMK76318.1 - 3.4e-21 75.3 0.0 1.1e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.28 AMK76318.1 - 1.6e-19 70.3 0.1 2.6e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NMO PF03060.15 AMK76318.1 - 0.00037 20.0 0.1 0.00072 19.0 0.0 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 AMK76318.1 - 0.053 12.5 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PrpR_N PF06506.11 AMK76318.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Propionate catabolism activator YacG PF03884.14 AMK76319.1 - 4.6e-23 80.7 1.4 5.3e-23 80.5 1.4 1.1 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG DUF2256 PF10013.9 AMK76319.1 - 0.061 13.5 3.6 2.2 8.4 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) ZapD PF07072.11 AMK76320.1 - 4.7e-73 245.4 1.0 5.6e-73 245.2 0.5 1.3 2 0 0 2 2 2 1 Cell division protein CoaE PF01121.20 AMK76321.1 - 5.3e-66 221.7 0.1 6.6e-66 221.4 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase SKI PF01202.22 AMK76321.1 - 0.00014 22.1 0.2 0.22 11.6 0.2 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_17 PF13207.6 AMK76321.1 - 0.00019 21.8 0.5 0.0025 18.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AMK76321.1 - 0.00099 19.7 0.6 0.0058 17.2 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AMK76321.1 - 0.0056 16.9 0.0 0.0097 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AMK76321.1 - 0.01 16.0 0.5 0.082 13.0 0.5 2.2 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_33 PF13671.6 AMK76321.1 - 0.041 14.0 0.0 0.29 11.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 AMK76321.1 - 0.062 13.0 0.4 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.17 AMK76321.1 - 0.071 12.9 0.4 0.55 10.0 0.2 2.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AMK76321.1 - 0.14 12.7 0.2 0.22 12.0 0.2 1.7 1 1 0 1 1 1 0 ABC transporter PRK PF00485.18 AMK76321.1 - 0.28 10.9 2.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 AMK76321.1 - 0.4 10.4 1.3 0.8 9.5 1.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DiS_P_DiS PF06750.13 AMK76322.1 - 1.5e-33 114.7 0.9 2.8e-33 113.9 0.9 1.4 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 AMK76322.1 - 4.8e-26 91.3 11.2 4.8e-26 91.3 11.2 2.2 2 0 0 2 2 2 1 Type IV leader peptidase family DZR PF12773.7 AMK76322.1 - 0.06 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 AMK76322.1 - 0.16 11.4 3.3 5.7 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ZPR1 PF03367.13 AMK76322.1 - 0.28 11.0 0.5 0.4 10.5 0.5 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain UPF0547 PF10571.9 AMK76322.1 - 8.6 6.5 7.3 8.5 6.6 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 T2SSF PF00482.23 AMK76323.1 - 6.4e-64 213.5 4.6 1.2e-31 109.2 1.2 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F DUF4536 PF15055.6 AMK76323.1 - 0.023 14.9 0.3 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF2207 PF09972.9 AMK76323.1 - 0.024 13.4 2.1 0.047 12.5 0.8 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3899 PF13038.6 AMK76323.1 - 0.13 12.8 0.7 2 9.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) E1-E2_ATPase PF00122.20 AMK76323.1 - 0.38 10.3 7.1 0.66 9.5 0.8 3.2 2 1 1 3 3 3 0 E1-E2 ATPase DUF4870 PF09685.10 AMK76323.1 - 2.3 8.3 12.3 0.028 14.5 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) T2SSE PF00437.20 AMK76324.1 - 5.6e-89 297.8 0.8 7.9e-89 297.3 0.8 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AMK76324.1 - 8.7e-19 67.8 0.7 3.8e-18 65.7 0.1 2.3 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain PhoH PF02562.16 AMK76324.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 AMK76324.1 - 0.015 15.7 0.0 0.048 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AMK76324.1 - 0.018 15.3 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 AMK76324.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 AMK76324.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK76324.1 - 0.03 14.7 0.3 0.081 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PELOTA_1 PF15608.6 AMK76324.1 - 0.042 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 PELOTA RNA binding domain AAA_7 PF12775.7 AMK76324.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 AMK76324.1 - 0.34 10.8 1.7 15 5.5 0.0 2.5 1 1 1 2 2 2 0 NTPase ThiC_Rad_SAM PF01964.18 AMK76325.1 - 6.2e-197 654.4 0.0 7.4e-197 654.2 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 AMK76325.1 - 2.3e-31 107.4 0.0 4.9e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 ThiC-associated domain MutS_III PF05192.18 AMK76326.1 - 0.0076 16.5 4.5 0.0091 16.2 4.5 1.0 1 0 0 1 1 1 1 MutS domain III APG17 PF04108.12 AMK76326.1 - 0.0096 15.1 6.1 0.011 14.8 6.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 CLZ PF16526.5 AMK76326.1 - 0.6 10.5 9.5 5.1 7.5 0.4 3.3 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dad1 PF08649.10 AMK76326.1 - 1 9.6 3.9 6.6 7.0 0.7 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad1 polyprenyl_synt PF00348.17 AMK76327.1 - 3.4e-75 252.4 0.5 4.5e-75 252.0 0.5 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEAT_PBS PF03130.16 AMK76327.1 - 0.069 13.9 2.5 2.3 9.1 0.4 3.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Ribosomal_L21p PF00829.21 AMK76328.1 - 7.1e-41 138.6 4.3 7.8e-41 138.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Biotin_lipoyl PF00364.22 AMK76328.1 - 0.044 13.6 0.6 0.66 9.8 0.3 2.3 1 1 1 2 2 2 0 Biotin-requiring enzyme Prot_ATP_OB_N PF17758.1 AMK76328.1 - 0.11 12.2 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Ribosomal_L27 PF01016.19 AMK76329.1 - 2.1e-40 136.6 4.3 2.3e-40 136.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Peptidase_M23 PF01551.22 AMK76329.1 - 0.03 14.5 0.5 0.13 12.4 0.1 1.9 2 0 0 2 2 2 0 Peptidase family M23 Formyl_trans_C PF02911.18 AMK76329.1 - 0.088 13.0 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain GTP1_OBG PF01018.22 AMK76330.1 - 2.2e-57 193.0 5.1 2.9e-57 192.6 5.1 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AMK76330.1 - 1.5e-24 86.3 0.0 2.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AMK76330.1 - 7.9e-11 41.7 0.0 5.2e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 AMK76330.1 - 0.0011 18.5 0.0 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 AMK76330.1 - 0.0021 17.1 0.1 0.37 9.7 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Gtr1_RagA PF04670.12 AMK76330.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 AMK76330.1 - 0.087 12.7 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 AMK76330.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AA_kinase PF00696.28 AMK76331.1 - 3.3e-48 164.4 1.6 5.6e-48 163.6 1.6 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 AMK76331.1 - 1.3e-19 69.9 0.2 3.4e-19 68.6 0.2 1.7 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 AMK76331.1 - 0.064 13.1 0.1 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 PUA-like domain ParA PF10609.9 AMK76332.1 - 1.5e-100 335.7 0.2 2e-100 335.3 0.2 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 AMK76332.1 - 7.9e-17 61.2 0.1 5.7e-16 58.4 0.2 2.4 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 AMK76332.1 - 1.9e-14 53.8 0.0 6.1e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AMK76332.1 - 1.4e-11 44.6 1.1 6.3e-09 36.0 0.2 2.3 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 AMK76332.1 - 1.2e-07 31.3 0.8 5.1e-07 29.2 0.8 1.9 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 AMK76332.1 - 1.3e-05 24.8 0.1 0.00021 20.8 0.1 2.3 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AMK76332.1 - 2.5e-05 23.6 1.2 0.00031 20.0 0.5 2.7 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.11 AMK76332.1 - 0.00089 18.6 0.1 0.002 17.5 0.1 1.6 2 0 0 2 2 2 1 VirC1 protein AAA_25 PF13481.6 AMK76332.1 - 0.018 14.6 0.2 0.045 13.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 AMK76332.1 - 0.033 13.7 0.5 0.75 9.2 0.2 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 AMK76332.1 - 0.04 13.7 0.4 0.084 12.7 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 AMK76332.1 - 0.047 12.7 0.3 0.14 11.1 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 AMK76332.1 - 0.076 12.6 0.3 0.16 11.5 0.1 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FTHFS PF01268.19 AMK76332.1 - 0.076 11.2 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Phage_tube PF04985.14 AMK76332.1 - 0.11 12.2 0.0 3.1 7.5 0.0 2.8 2 1 1 3 3 3 0 Phage tail tube protein FII YkuD PF03734.14 AMK76333.1 - 3.6e-24 85.8 0.0 6.9e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain SPOR PF05036.13 AMK76333.1 - 2.1e-12 47.2 0.0 4.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Sporulation related domain Ldt_C PF17969.1 AMK76333.1 - 3.8e-06 27.5 0.2 1.5e-05 25.6 0.1 2.1 2 0 0 2 2 2 1 L,D-transpeptidase C-terminal domain LysM PF01476.20 AMK76333.1 - 0.00043 20.3 0.0 0.0015 18.6 0.0 2.0 1 0 0 1 1 1 1 LysM domain TraH_2 PF06871.11 AMK76333.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 TraH_2 MLTD_N PF06474.12 AMK76333.1 - 0.099 12.8 1.1 0.21 11.8 1.1 1.5 1 0 0 1 1 1 0 MltD lipid attachment motif Arm-DNA-bind_4 PF14657.6 AMK76333.1 - 0.18 11.6 0.4 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain EAL PF00563.20 AMK76334.1 - 3.8e-69 232.8 0.6 7.8e-69 231.8 0.1 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK76334.1 - 3.5e-50 169.9 0.2 6.8e-50 169.0 0.2 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 AMK76334.1 - 2.7e-17 63.3 0.1 1e-16 61.5 0.1 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AMK76334.1 - 5.2e-10 40.1 0.0 3.4e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AMK76334.1 - 2.9e-07 30.9 0.0 9e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain CBS PF00571.28 AMK76334.1 - 1.7e-06 28.4 0.0 1.5e-05 25.3 0.0 2.7 3 0 0 3 3 3 1 CBS domain PLU-1 PF08429.11 AMK76334.1 - 0.025 13.8 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 PLU-1-like protein tRNA-synt_1g PF09334.11 AMK76338.1 - 5e-160 532.5 0.0 6.6e-160 532.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 AMK76338.1 - 8.7e-26 89.9 0.0 1.6e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 AMK76338.1 - 8.4e-14 50.7 0.1 2e-08 33.0 0.1 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AMK76338.1 - 5.9e-12 45.5 0.1 9e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AMK76338.1 - 1.6e-06 27.3 0.0 0.001 18.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (K) tRNA-synt_1b PF00579.25 AMK76338.1 - 0.0099 15.2 0.0 2.1 7.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Fer4_21 PF14697.6 AMK76339.1 - 2.5e-15 56.3 15.3 2.5e-15 56.3 15.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 AMK76339.1 - 3.9e-14 52.0 6.2 3.9e-14 52.0 6.2 2.2 2 0 0 2 2 1 1 Putative Fe-S cluster Fer4 PF00037.27 AMK76339.1 - 3.1e-08 33.1 25.7 3.5e-05 23.4 5.2 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AMK76339.1 - 1.9e-06 28.7 19.9 0.0011 19.8 4.3 3.0 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AMK76339.1 - 3.6e-05 23.8 25.0 0.00013 22.0 12.8 3.2 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK76339.1 - 9.1e-05 23.0 21.2 0.0025 18.4 1.9 3.1 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK76339.1 - 9.5e-05 22.5 14.1 9.5e-05 22.5 14.1 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK76339.1 - 0.0008 19.4 5.7 0.0008 19.4 5.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AMK76339.1 - 0.014 15.5 4.4 0.014 15.5 4.4 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain CD225 PF04505.12 AMK76339.1 - 0.058 13.5 0.1 0.098 12.8 0.1 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Fer4_17 PF13534.6 AMK76339.1 - 0.26 11.9 25.6 0.69 10.5 2.1 3.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK76339.1 - 1.2 9.7 22.9 0.26 11.7 4.7 3.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain Cas_Cas2CT1978 PF09707.10 AMK76340.1 - 9e-37 125.0 0.1 1e-36 124.8 0.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas2CT1978) Cas_Cas1 PF01867.16 AMK76341.1 - 6.9e-18 64.8 0.0 4.1e-10 39.3 0.0 2.1 1 1 1 2 2 2 2 CRISPR associated protein Cas1 CRISPR_assoc PF08798.11 AMK76342.1 - 5.3e-43 147.7 0.0 1.2e-42 146.6 0.0 1.5 1 1 0 1 1 1 1 CRISPR associated protein Cas_Cas5d PF09704.10 AMK76343.1 - 1.4e-40 139.5 0.4 1.6e-40 139.3 0.4 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) Cas_CT1975 PF09344.10 AMK76344.1 - 8.8e-100 334.7 0.0 1.1e-99 334.4 0.0 1.0 1 0 0 1 1 1 1 CT1975-like protein Cas_Cas7 PF05107.12 AMK76344.1 - 1.1e-05 25.1 0.0 2.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 CRISPR-associated protein Cas7 ANAPC5 PF12862.7 AMK76344.1 - 0.0097 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 CRISPR_Cse2 PF09485.10 AMK76345.1 - 2.5e-20 73.5 0.2 3e-20 73.2 0.2 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) CRISPR_Cse1 PF09481.10 AMK76346.1 - 1.1e-106 357.7 4.6 1.2e-106 357.5 4.6 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) HicA_toxin PF07927.12 AMK76347.1 - 4.3e-13 49.1 0.2 4.8e-13 48.9 0.2 1.0 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, ACT_5 PF13710.6 AMK76347.1 - 0.00015 21.5 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 ACT domain HicB_lk_antitox PF15919.5 AMK76348.1 - 6.6e-08 32.7 0.1 7.1e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system DUF1902 PF08972.11 AMK76348.1 - 0.0071 16.3 0.0 0.0083 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) HD_6 PF18019.1 AMK76349.1 - 4.8e-47 160.6 1.2 4.8e-47 160.6 1.2 1.9 2 0 0 2 2 2 1 HD domain DEAD PF00270.29 AMK76349.1 - 2.5e-05 24.1 0.4 0.00017 21.4 0.4 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK76349.1 - 0.00064 20.0 0.0 0.011 16.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AMK76349.1 - 0.0095 15.9 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 AMK76350.1 - 1.7e-11 44.1 0.1 2.6e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF576 PF04507.12 AMK76350.1 - 0.099 12.1 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Csa1 family DUF805 PF05656.14 AMK76351.1 - 5.5e-29 100.7 1.4 6.4e-29 100.4 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF5518 PF17647.1 AMK76351.1 - 0.068 13.3 2.3 0.13 12.4 2.3 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5518) UPF0370 PF13980.6 AMK76351.1 - 0.069 13.2 4.8 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DUF308 PF03729.13 AMK76351.1 - 0.2 12.0 6.7 2.6 8.4 1.0 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Pmp3 PF01679.17 AMK76351.1 - 0.21 11.8 6.4 0.11 12.8 2.9 2.0 2 0 0 2 2 2 0 Proteolipid membrane potential modulator BPD_transp_1 PF00528.22 AMK76351.1 - 1.1 9.0 9.0 1.5 8.5 3.8 2.1 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component Abhydrolase_1 PF00561.20 AMK76352.1 - 2.1e-17 63.7 0.0 1.1e-16 61.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK76352.1 - 2.7e-14 54.3 0.3 2e-12 48.2 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK76352.1 - 2e-10 40.3 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AMK76352.1 - 2.2e-06 28.0 0.0 3.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 AMK76352.1 - 0.00024 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 AMK76352.1 - 0.0048 16.7 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 AMK76352.1 - 0.01 15.8 0.0 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LPAM_1 PF08139.12 AMK76352.1 - 0.13 12.8 0.2 0.13 12.8 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Palm_thioest PF02089.15 AMK76352.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase FA_desaturase PF00487.24 AMK76354.1 - 2.1e-30 106.4 11.9 2.7e-30 106.1 11.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase PG_binding_3 PF09374.10 AMK76354.1 - 0.18 12.1 0.1 9.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Predicted Peptidoglycan domain PRA-CH PF01502.18 AMK76355.1 - 2.8e-34 116.8 0.1 3.5e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase DUF3318 PF11780.8 AMK76355.1 - 0.067 13.1 0.3 0.082 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) His_biosynth PF00977.21 AMK76356.1 - 1.7e-91 305.8 1.9 1.9e-91 305.6 1.9 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AMK76356.1 - 2.6e-07 30.0 0.4 0.00018 20.7 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AMK76356.1 - 2e-06 27.5 4.6 0.01 15.2 0.8 2.1 1 1 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 AMK76356.1 - 1.1e-05 24.9 0.3 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase ThiG PF05690.14 AMK76356.1 - 3.6e-05 23.2 1.7 0.089 12.1 0.1 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 AMK76356.1 - 0.0004 19.9 0.3 0.018 14.5 0.1 2.3 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 AMK76356.1 - 0.00067 18.8 0.9 0.13 11.2 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 AMK76356.1 - 0.0014 17.9 0.1 0.063 12.5 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase DUF561 PF04481.12 AMK76356.1 - 0.0081 15.4 0.1 0.79 8.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF561) TonB_2 PF13103.6 AMK76356.1 - 0.026 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 TonB C terminal PcrB PF01884.17 AMK76356.1 - 0.06 12.8 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 PcrB family Trp_syntA PF00290.20 AMK76356.1 - 0.078 11.8 1.1 0.11 11.3 0.2 1.6 2 0 0 2 2 2 0 Tryptophan synthase alpha chain FMN_dh PF01070.18 AMK76356.1 - 2 7.4 5.9 0.56 9.2 0.3 2.3 1 1 2 3 3 3 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 AMK76357.1 - 3.6e-79 265.4 2.4 4.1e-79 265.2 2.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AMK76357.1 - 1.4e-10 40.8 1.4 0.00021 20.5 0.2 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AMK76357.1 - 2.4e-06 27.2 4.6 0.0043 16.5 0.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase G3P_antiterm PF04309.12 AMK76357.1 - 0.00019 20.9 0.5 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 AMK76357.1 - 0.00026 20.4 1.6 0.051 12.9 0.1 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 AMK76357.1 - 0.00029 19.9 6.1 0.024 13.6 1.2 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 AMK76357.1 - 0.00078 18.8 1.7 0.05 12.9 0.1 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase Trp_syntA PF00290.20 AMK76357.1 - 0.0021 17.0 1.1 0.027 13.3 0.1 2.2 2 0 0 2 2 2 1 Tryptophan synthase alpha chain DeoC PF01791.9 AMK76357.1 - 0.0059 16.2 0.2 0.013 15.1 0.1 1.7 2 0 0 2 2 2 1 DeoC/LacD family aldolase PcrB PF01884.17 AMK76357.1 - 0.017 14.6 1.4 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 PcrB family IGPS PF00218.21 AMK76357.1 - 0.021 14.0 0.1 2.5 7.2 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Ribul_P_3_epim PF00834.19 AMK76357.1 - 0.1 11.9 1.4 0.12 11.8 0.2 1.7 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Transglut_core2 PF13369.6 AMK76357.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily GATase PF00117.28 AMK76358.1 - 1.4e-21 77.1 0.0 1.7e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AMK76358.1 - 3.5e-05 23.5 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 AMK76358.1 - 0.00081 19.2 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 IGPD PF00475.18 AMK76359.1 - 1.2e-62 210.5 0.3 1.6e-62 210.1 0.3 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF3458_C PF17432.2 AMK76360.1 - 3.9e-127 424.0 7.6 6.3e-127 423.3 7.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 AMK76360.1 - 1.2e-54 185.1 0.1 2.2e-54 184.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 AMK76360.1 - 4.9e-29 100.6 0.4 1.3e-28 99.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 AMK76360.1 - 6.6e-13 49.3 0.0 2.7e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2336 PF10098.9 AMK76360.1 - 0.01 15.3 1.0 0.067 12.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) PsiE PF06146.12 AMK76361.1 - 1.5e-18 66.9 7.0 1.5e-18 66.9 7.0 1.7 2 0 0 2 2 2 1 Phosphate-starvation-inducible E GPI2 PF06432.11 AMK76361.1 - 9.3 5.6 11.4 0.2 11.1 2.2 1.9 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF423 PF04241.15 AMK76362.1 - 2.6e-29 101.3 4.7 2.6e-29 101.3 4.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF423) DUF3169 PF11368.8 AMK76362.1 - 0.49 9.9 6.8 0.051 13.1 0.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2721 PF11026.8 AMK76362.1 - 4.5 7.2 8.1 0.93 9.4 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MoCF_biosynth PF00994.24 AMK76363.1 - 1.5e-32 112.2 0.2 1.8e-32 112.0 0.2 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain AI-2E_transport PF01594.16 AMK76364.1 - 1.2e-49 169.3 30.4 1.4e-49 169.1 30.4 1.0 1 0 0 1 1 1 1 AI-2E family transporter Rieske PF00355.26 AMK76365.1 - 1.7e-06 27.9 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CBS PF00571.28 AMK76366.1 - 2.2e-29 101.6 1.6 5.2e-15 55.6 0.1 2.2 2 0 0 2 2 2 2 CBS domain DUF465 PF04325.13 AMK76366.1 - 0.081 13.0 0.7 0.17 12.0 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF45 PF01863.17 AMK76367.1 - 1.5e-12 48.0 0.3 1.6e-12 47.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AMK76367.1 - 6.5e-05 23.1 0.3 9.1e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 WLM domain DUF2064 PF09837.9 AMK76369.1 - 2.7e-35 120.9 0.0 4.6e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) NTP_transf_3 PF12804.7 AMK76369.1 - 4.4e-05 23.9 0.3 5.7e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CofC PF01983.16 AMK76369.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like FA_hydroxylase PF04116.13 AMK76370.1 - 9.4e-27 94.0 6.1 1.5e-26 93.3 6.1 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Glycos_transf_2 PF00535.26 AMK76371.1 - 1.7e-17 63.8 0.0 2.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK76371.1 - 9.8e-06 25.2 0.0 0.00016 21.2 0.0 2.1 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AMK76371.1 - 3.2e-05 23.9 0.1 5.6e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AMK76371.1 - 0.0041 17.0 0.5 0.01 15.7 0.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AMK76371.1 - 0.0062 16.0 0.9 0.091 12.2 0.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF3641 PF12345.8 AMK76372.1 - 1.4e-57 193.5 0.0 2e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 AMK76372.1 - 2e-09 38.0 0.0 3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AMK76372.1 - 4.9e-05 23.6 0.0 9.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AMK76372.1 - 0.0033 17.5 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3047 PF11249.8 AMK76373.1 - 3.2e-61 206.1 1.2 3.7e-61 205.9 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3047) SNARE_assoc PF09335.11 AMK76374.1 - 2e-26 92.8 8.6 2e-26 92.8 8.6 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2976 PF11190.8 AMK76374.1 - 0.059 13.2 2.5 2.9 7.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) SpoVAB PF13782.6 AMK76374.1 - 0.9 9.9 5.5 0.43 10.9 0.8 2.5 3 0 0 3 3 3 0 Stage V sporulation protein AB Pyr_redox_2 PF07992.14 AMK76375.1 - 6.2e-56 189.8 0.0 8.2e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AMK76375.1 - 1.1e-30 106.1 0.0 2e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AMK76375.1 - 7e-24 84.2 1.2 3.1e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK76375.1 - 5.7e-13 48.8 0.0 8.5e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AMK76375.1 - 4.2e-12 45.9 3.1 2.8e-06 26.7 2.4 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AMK76375.1 - 5.7e-10 39.3 3.4 6.8e-05 23.0 1.7 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AMK76375.1 - 3.1e-08 32.8 2.8 0.0006 18.6 2.8 3.3 3 1 1 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 AMK76375.1 - 2.2e-07 30.6 4.3 3.3e-05 23.4 3.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AMK76375.1 - 3.5e-07 29.7 0.3 0.011 15.1 0.5 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 AMK76375.1 - 2e-05 24.4 9.9 0.028 14.0 5.7 3.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AMK76375.1 - 5.2e-05 22.5 6.4 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.6 AMK76375.1 - 6.5e-05 23.3 0.0 0.077 13.4 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding 3HCDH_N PF02737.18 AMK76375.1 - 7.5e-05 22.7 0.2 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 AMK76375.1 - 0.00037 21.0 0.1 0.61 10.6 0.0 2.4 2 0 0 2 2 2 2 XdhC Rossmann domain FAD_binding_2 PF00890.24 AMK76375.1 - 0.00068 18.8 10.6 0.002 17.3 7.1 2.8 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 AMK76375.1 - 0.00069 19.0 5.3 0.3 10.3 3.4 2.2 2 0 0 2 2 2 2 FAD binding domain UDPG_MGDP_dh_N PF03721.14 AMK76375.1 - 0.0012 18.4 0.4 1.2 8.6 1.1 3.1 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 AMK76375.1 - 0.0019 17.6 0.1 1.5 8.2 0.2 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 AMK76375.1 - 0.0044 16.2 0.0 0.024 13.8 0.0 2.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.21 AMK76375.1 - 0.028 13.8 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 AMK76375.1 - 0.028 14.7 0.4 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 AMK76375.1 - 0.029 13.6 1.1 0.092 12.0 0.5 2.0 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 AMK76375.1 - 0.73 9.5 4.6 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ABM PF03992.16 AMK76376.1 - 9.1e-06 25.7 0.1 1.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_2 PF07883.11 AMK76377.1 - 1.3e-14 53.6 0.0 4.2e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 AMK76377.1 - 0.002 17.8 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Bcl-2_BAD PF10514.9 AMK76377.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Asp_Glu_race PF01177.22 AMK76378.1 - 1.2e-34 120.1 0.1 1.4e-34 119.9 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase GST_N_3 PF13417.6 AMK76379.1 - 7.7e-13 48.7 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK76379.1 - 2.2e-12 47.1 0.0 4.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK76379.1 - 3.9e-09 36.7 0.0 6.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK76379.1 - 3.3e-07 30.2 0.0 9.7e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AMK76379.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AMK76379.1 - 0.0063 16.7 0.0 0.06 13.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AMK76379.1 - 0.095 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Methyltransf_31 PF13847.6 AMK76380.1 - 5.3e-32 110.7 0.0 8.4e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76380.1 - 1.9e-20 73.3 0.0 4.1e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK76380.1 - 4.7e-20 72.0 0.0 9.1e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK76380.1 - 4.9e-16 58.8 0.0 1.4e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AMK76380.1 - 3.1e-12 46.7 0.0 5.8e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76380.1 - 9.5e-12 45.5 0.0 1.7e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AMK76380.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 AMK76380.1 - 0.00011 22.1 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase FtsJ PF01728.19 AMK76380.1 - 0.0003 20.9 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 AMK76380.1 - 0.0019 17.7 0.0 0.058 12.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 AMK76380.1 - 0.002 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 AMK76380.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 AMK76380.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 AMK76380.1 - 0.08 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 AMK76380.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Fibrillarin PF01269.17 AMK76380.1 - 0.16 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltr_RsmB-F PF01189.17 AMK76380.1 - 0.17 11.5 0.0 3 7.4 0.0 2.2 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_29 PF03141.16 AMK76380.1 - 0.19 10.2 0.0 0.37 9.3 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 AMK76380.1 - 0.28 10.8 0.5 2 8.0 0.5 2.0 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CHASE PF03924.13 AMK76381.1 - 1.7e-45 155.3 0.1 9e-45 152.9 0.2 2.1 2 0 0 2 2 2 1 CHASE domain HATPase_c PF02518.26 AMK76381.1 - 4.9e-27 94.7 0.0 9.5e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK76381.1 - 5e-26 91.1 0.1 2.6e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain MASE1 PF05231.14 AMK76381.1 - 2.9e-22 79.2 24.5 2.9e-22 79.2 24.5 1.5 2 0 0 2 2 2 1 MASE1 PAS_8 PF13188.7 AMK76381.1 - 4.9e-19 67.9 0.1 4.8e-09 36.0 0.0 3.2 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 AMK76381.1 - 1.2e-18 66.9 0.3 4e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AMK76381.1 - 1.1e-15 57.6 0.0 1e-09 38.4 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AMK76381.1 - 1.6e-15 57.2 0.0 4.8e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain Hpt PF01627.23 AMK76381.1 - 9.1e-08 32.3 0.5 3.7e-07 30.3 0.3 2.2 2 0 0 2 2 2 1 Hpt domain PAS_3 PF08447.12 AMK76381.1 - 8.6e-07 29.2 0.0 0.0002 21.6 0.0 2.8 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AMK76381.1 - 6.6e-06 26.3 0.1 0.00021 21.5 0.0 2.8 2 1 0 2 2 2 1 PAS fold ADH_N PF08240.12 AMK76382.1 - 3.5e-25 88.0 4.4 3.5e-25 88.0 4.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AMK76382.1 - 8.6e-22 77.5 0.0 1.7e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AMK76382.1 - 4.4e-06 27.8 0.0 8.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 AMK76382.1 - 7.2e-06 25.5 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 AMK76382.1 - 0.0003 20.1 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 AMK76382.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.19 AMK76382.1 - 0.022 13.5 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Glu_dehyd_C PF16912.5 AMK76382.1 - 0.027 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus CoA_binding PF02629.19 AMK76382.1 - 0.084 13.6 0.0 1.4 9.6 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain Shikimate_DH PF01488.20 AMK76382.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fer4 PF00037.27 AMK76383.1 - 2.9e-10 39.5 20.6 2.6e-06 27.0 5.3 3.2 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_7 PF12838.7 AMK76383.1 - 4.1e-06 27.3 28.0 0.0002 21.9 16.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK76383.1 - 2.4e-05 24.4 13.1 4.6e-05 23.5 13.2 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK76383.1 - 4e-05 23.6 24.0 0.00029 20.9 13.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK76383.1 - 4.3e-05 24.4 12.7 0.029 15.3 5.7 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AMK76383.1 - 0.0002 21.3 12.6 0.064 13.4 2.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AMK76383.1 - 0.00034 20.6 19.0 0.028 14.5 5.2 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain GF_recep_IV PF14843.6 AMK76383.1 - 0.00042 20.1 8.6 0.00053 19.8 8.6 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV Fer4_21 PF14697.6 AMK76383.1 - 0.0014 18.7 18.2 0.0034 17.5 18.2 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK76383.1 - 0.011 16.2 2.8 0.011 16.2 2.8 2.9 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AMK76383.1 - 0.03 15.2 21.3 0.63 11.1 8.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AMK76383.1 - 0.11 13.0 4.2 0.11 13.0 4.2 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK76383.1 - 2.2 8.8 15.7 7.2e+02 0.7 15.7 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_11 PF13247.6 AMK76383.1 - 4.3 7.5 12.2 0.81 9.8 4.5 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AMK76383.1 - 7.9 6.7 15.3 0.4 10.9 6.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain CTP_transf_like PF01467.26 AMK76384.1 - 6.2e-22 78.3 0.0 7.4e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AMK76384.1 - 6.3e-06 26.0 0.1 5.4e-05 23.0 0.1 1.9 1 1 1 2 2 2 1 Citrate lyase ligase C-terminal domain Cons_hypoth95 PF03602.15 AMK76385.1 - 2e-55 187.2 0.0 2.3e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AMK76385.1 - 1.1e-08 34.8 0.0 1.8e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AMK76385.1 - 3.9e-07 30.0 0.0 4.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76385.1 - 5.7e-06 27.0 0.0 8.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AMK76385.1 - 2.4e-05 23.5 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 AMK76385.1 - 3.4e-05 23.7 0.0 4.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltr_RsmB-F PF01189.17 AMK76385.1 - 9.7e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltrans_SAM PF10672.9 AMK76385.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase RsmJ PF04378.13 AMK76385.1 - 0.003 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ PrmA PF06325.13 AMK76385.1 - 0.0036 16.7 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 AMK76385.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.15 AMK76385.1 - 0.041 13.5 0.0 4.8 6.8 0.0 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase UPF0020 PF01170.18 AMK76385.1 - 0.052 13.2 0.1 0.68 9.6 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 TRM PF02005.16 AMK76385.1 - 0.083 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Peptidase_M16_C PF05193.21 AMK76386.1 - 5.3e-38 130.9 0.0 4.5e-37 127.8 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AMK76386.1 - 2.7e-12 46.9 0.0 1.2e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF3089 PF11288.8 AMK76386.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) 7TMR-DISMED2 PF07696.11 AMK76386.1 - 0.065 13.3 0.1 8.3 6.5 0.0 2.9 3 0 0 3 3 3 0 7TMR-DISM extracellular 2 Peptidase_M16 PF00675.20 AMK76387.1 - 8.5e-29 100.5 0.0 2.2e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 AMK76387.1 - 4.1e-24 85.6 0.2 1e-23 84.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF4549 PF15082.6 AMK76387.1 - 0.012 15.4 1.2 0.081 12.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) UbiA PF01040.18 AMK76388.1 - 1.6e-63 214.4 24.0 1.9e-63 214.1 24.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TraS PF10624.9 AMK76388.1 - 0.053 13.5 0.8 0.053 13.5 0.8 1.8 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS DUF1129 PF06570.11 AMK76388.1 - 1.7 8.1 16.0 0.059 12.9 3.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) MitoNEET_N PF10660.9 AMK76388.1 - 4.5 7.4 9.8 2.6 8.1 0.6 3.4 3 1 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus Glycos_trans_3N PF02885.17 AMK76389.1 - 3.7e-15 55.5 0.2 1.1e-14 54.0 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 AMK76389.1 - 2.5e-10 40.4 0.0 4.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain GNAT_acetyltr_2 PF13718.6 AMK76389.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 PilZ PF07238.14 AMK76390.1 - 1.2e-09 38.4 0.0 7.4e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 PilZ domain SLT PF01464.20 AMK76391.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain FKBP_C PF00254.28 AMK76392.1 - 3.4e-27 94.6 0.0 4.9e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 AMK76392.1 - 6.7e-11 43.0 0.0 1.2e-10 42.2 0.0 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ish1 PF10281.9 AMK76394.1 - 0.00068 19.9 0.1 0.0023 18.2 0.4 1.7 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein UPF0020 PF01170.18 AMK76395.1 - 9.7e-45 152.7 0.0 3.6e-44 150.8 0.0 2.0 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.9 AMK76395.1 - 1.3e-21 77.0 0.0 2.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AMK76395.1 - 4.7e-15 55.7 0.0 3.7e-11 43.0 0.0 4.0 4 0 0 4 4 4 1 Conserved hypothetical protein 95 THUMP PF02926.17 AMK76395.1 - 2e-13 50.6 0.0 3.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Methyltransf_31 PF13847.6 AMK76395.1 - 0.0019 18.0 0.4 1 9.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76395.1 - 0.0062 17.2 0.2 0.28 11.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_3 PF01596.17 AMK76395.1 - 0.008 15.4 0.1 0.36 10.0 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_15 PF09445.10 AMK76395.1 - 0.023 14.3 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 AMK76395.1 - 0.033 13.9 0.0 0.19 11.5 0.0 2.0 1 1 0 2 2 2 0 Met-10+ like-protein Methyltransf_23 PF13489.6 AMK76395.1 - 0.055 13.3 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Acylphosphatase PF00708.18 AMK76396.1 - 1.5e-26 92.6 0.1 1.7e-26 92.4 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Porphobil_deam PF01379.20 AMK76397.1 - 4.7e-83 277.7 0.0 5.8e-83 277.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 AMK76397.1 - 3.9e-17 62.4 0.0 7.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain HEM4 PF02602.15 AMK76398.1 - 1.1e-44 152.6 0.2 1.3e-44 152.3 0.2 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD SBP_bac_3 PF00497.20 AMK76398.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 HemX PF04375.14 AMK76399.1 - 3.1e-56 191.1 8.8 4e-56 190.8 8.8 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1917 PF08939.10 AMK76399.1 - 0.021 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) Baculo_PEP_C PF04513.12 AMK76399.1 - 0.022 14.8 3.9 0.022 14.8 3.9 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 AMK76399.1 - 0.055 13.9 2.9 1.1 9.7 0.0 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RNase_H PF00075.24 AMK76399.1 - 0.068 13.3 0.1 0.21 11.7 0.1 1.9 1 1 0 1 1 1 0 RNase H ABC_tran_CTD PF16326.5 AMK76399.1 - 0.11 12.7 1.5 0.36 11.1 0.2 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain Acyl-CoA_dh_C PF12806.7 AMK76399.1 - 0.16 12.2 0.9 1.4 9.1 0.8 2.5 1 1 2 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Fez1 PF06818.15 AMK76399.1 - 0.18 12.3 6.8 0.066 13.7 1.0 2.3 2 0 0 2 2 2 0 Fez1 DUF948 PF06103.11 AMK76399.1 - 3.1 8.1 8.6 0.1 12.8 0.6 2.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 AMK76399.1 - 6.6 6.0 5.0 1.2 8.5 1.3 1.5 2 0 0 2 2 2 0 FAM76 protein NPV_P10 PF05531.12 AMK76399.1 - 7.2 7.1 7.6 3.7 8.1 1.1 3.5 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein HemY_N PF07219.13 AMK76400.1 - 7.8e-30 103.2 0.8 7.8e-30 103.2 0.8 3.4 4 0 0 4 4 3 1 HemY protein N-terminus TPR_8 PF13181.6 AMK76400.1 - 5.3e-09 35.6 6.0 0.002 18.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK76400.1 - 2e-07 31.3 9.2 0.29 12.1 0.0 6.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 AMK76400.1 - 2.1e-07 31.3 6.2 0.0031 18.0 0.0 4.0 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 AMK76400.1 - 8.2e-06 25.5 4.2 0.55 10.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 AMK76400.1 - 1.5e-05 24.7 10.5 0.047 13.8 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 AMK76400.1 - 2.4e-05 24.1 6.5 0.0014 18.4 1.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 AMK76400.1 - 4.3e-05 23.7 12.1 0.12 12.7 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK76400.1 - 6.9e-05 23.0 4.6 0.02 15.1 0.0 3.6 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 AMK76400.1 - 0.0004 19.9 13.3 0.0074 15.7 0.5 2.6 2 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 AMK76400.1 - 0.0014 18.4 5.4 1.5 8.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 AMK76400.1 - 0.0016 18.7 0.5 1.9 9.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Lys_export PF03956.13 AMK76400.1 - 0.0083 15.7 0.6 0.016 14.7 0.6 1.5 1 0 0 1 1 1 1 Lysine exporter LysO TPR_6 PF13174.6 AMK76400.1 - 0.016 15.8 8.9 2.8 8.8 0.0 5.0 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 AMK76400.1 - 0.022 14.9 2.6 1.9 8.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Adeno_E3_15_3 PF03307.14 AMK76400.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region DUF4919 PF16266.5 AMK76400.1 - 0.16 11.9 0.1 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) Response_reg PF00072.24 AMK76401.1 - 5.4e-28 97.4 0.0 9.1e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AMK76401.1 - 3.1e-21 75.8 0.1 6.7e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AMK76401.1 - 3.5e-19 68.8 0.1 1.2e-18 67.1 0.1 2.0 1 0 0 1 1 1 1 HD domain DUF2288 PF10052.9 AMK76401.1 - 0.048 13.7 0.1 0.48 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2288) SpoIIE PF07228.12 AMK76402.1 - 2.7e-31 109.0 1.0 4e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 AMK76402.1 - 5.5e-27 94.2 0.4 1.3e-26 93.0 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain UbiD PF01977.16 AMK76403.1 - 7e-176 585.0 0.0 8e-176 584.8 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Cyt-b5 PF00173.28 AMK76403.1 - 0.076 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain FtsX PF02687.21 AMK76404.1 - 1.6e-08 34.9 11.1 3.8e-07 30.5 5.5 5.4 6 0 0 6 6 6 2 FtsX-like permease family Reticulon PF02453.17 AMK76404.1 - 0.67 9.9 8.6 0.11 12.4 0.5 3.3 4 0 0 4 4 4 0 Reticulon AcrZ PF10766.9 AMK76404.1 - 1 9.0 4.8 0.57 9.8 0.3 2.6 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ ABC_tran PF00005.27 AMK76405.1 - 6e-34 117.5 0.0 7.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK76405.1 - 2.3e-06 27.6 2.3 0.014 15.2 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK76405.1 - 0.00013 21.5 0.1 0.063 12.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AMK76405.1 - 0.00018 22.0 0.6 0.00029 21.3 0.6 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AMK76405.1 - 0.00022 20.9 0.3 0.00041 20.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK76405.1 - 0.0024 17.8 0.2 0.004 17.1 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 AMK76405.1 - 0.0028 17.9 0.1 0.0094 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 AMK76405.1 - 0.024 14.8 0.4 0.041 14.0 0.4 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 AMK76405.1 - 0.028 14.5 1.1 0.039 14.0 0.3 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AMK76405.1 - 0.034 13.9 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AMK76405.1 - 0.071 12.6 0.1 0.17 11.4 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 AMK76405.1 - 0.091 12.5 0.1 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AMK76405.1 - 0.093 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AMK76405.1 - 0.096 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 AMK76405.1 - 0.096 12.9 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 AMK76405.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 AMK76405.1 - 0.14 11.7 0.2 0.23 11.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 AMK76405.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 AMK76405.1 - 0.31 10.7 0.2 2 8.1 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Lipase_GDSL_2 PF13472.6 AMK76406.1 - 2.4e-18 67.1 0.0 3.1e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AMK76406.1 - 3.1e-09 37.1 0.0 3.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 AMK76406.1 - 0.015 14.5 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 OSK domain Glycos_transf_2 PF00535.26 AMK76407.1 - 4.4e-21 75.4 0.0 7.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK76407.1 - 2.4e-11 44.0 0.0 4e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AMK76407.1 - 7.7e-08 32.5 1.7 1e-07 32.1 1.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AMK76407.1 - 5.7e-06 25.9 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 AMK76407.1 - 0.00011 21.8 0.0 0.00028 20.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK76407.1 - 0.0088 16.5 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Caveolin PF01146.17 AMK76407.1 - 0.3 11.0 1.1 0.52 10.3 1.1 1.4 1 0 0 1 1 1 0 Caveolin Acetyltransf_7 PF13508.7 AMK76408.1 - 1.4e-05 25.4 0.0 4.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK76408.1 - 2.1e-05 24.7 0.0 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AMK76408.1 - 3.3e-05 24.0 0.0 0.008 16.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AMK76408.1 - 4.3e-05 23.5 0.0 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK76408.1 - 0.2 11.8 0.0 0.55 10.4 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase CPSase_L_D2 PF02786.17 AMK76410.1 - 9.5e-75 250.7 0.1 1.6e-74 250.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AMK76410.1 - 7.8e-43 145.5 0.0 1.5e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AMK76410.1 - 1.3e-38 131.4 0.0 2.6e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AMK76410.1 - 4.1e-10 39.6 0.0 8.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AMK76410.1 - 3.9e-07 29.8 0.0 6.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AMK76410.1 - 0.00035 20.2 0.0 0.00092 18.9 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 AMK76410.1 - 0.054 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.14 AMK76410.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 AMK76410.1 - 0.075 12.6 0.0 0.3 10.7 0.0 2.2 1 1 0 1 1 1 0 ATP-grasp domain PYC_OADA PF02436.18 AMK76411.1 - 3.9e-57 193.2 0.1 6.7e-57 192.4 0.1 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 AMK76411.1 - 3.4e-51 174.3 0.0 4.7e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AMK76411.1 - 2.2e-18 65.8 1.6 5.1e-18 64.7 1.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AMK76411.1 - 1.4e-07 31.3 3.3 0.0024 17.7 0.2 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 AMK76411.1 - 0.00019 21.3 0.4 0.00077 19.4 0.2 2.1 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 AMK76411.1 - 0.0012 18.1 0.4 0.031 13.5 0.1 2.8 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 AMK76411.1 - 0.0028 17.2 0.2 0.0051 16.3 0.2 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_3 PF13437.6 AMK76411.1 - 0.0087 16.8 1.1 0.2 12.4 0.3 2.6 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 AMK76411.1 - 0.031 14.2 0.2 0.076 12.9 0.2 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Sua5_yciO_yrdC PF01300.18 AMK76412.1 - 9.5e-62 207.7 0.0 1.6e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 AMK76412.1 - 3.3e-22 79.5 0.0 5.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding MafB19-deam PF14437.6 AMK76413.1 - 2.5e-31 108.3 0.0 2.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 AMK76413.1 - 3e-28 97.7 0.0 4.4e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 AMK76413.1 - 7.7e-06 26.0 0.0 1.9e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 AMK76413.1 - 0.00022 21.3 0.0 0.0004 20.5 0.0 1.4 2 0 0 2 2 2 1 APOBEC2 Bd3614-deam PF14439.6 AMK76413.1 - 0.00034 20.7 0.1 0.00051 20.1 0.1 1.4 1 1 0 1 1 1 1 Bd3614-like deaminase NAD2 PF18782.1 AMK76413.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 AMK76413.1 - 0.0017 18.5 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 APOBEC3 NAD1 PF18778.1 AMK76413.1 - 0.0029 17.7 0.0 0.0054 16.9 0.0 1.4 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 AMK76413.1 - 0.0065 16.4 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Inv-AAD PF18785.1 AMK76413.1 - 0.046 13.6 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC4_like PF18774.1 AMK76413.1 - 0.11 12.5 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase DUF2389 PF09493.10 AMK76414.1 - 1.6e-17 63.9 0.9 1.9e-17 63.6 0.9 1.1 1 0 0 1 1 1 1 Tryptophan-rich protein (DUF2389) DNA_photolyase PF00875.18 AMK76415.1 - 1.1e-13 51.5 1.6 1.3e-13 51.2 1.6 1.1 1 0 0 1 1 1 1 DNA photolyase DUF2256 PF10013.9 AMK76415.1 - 4.3e-09 36.4 4.8 6.2e-09 35.8 4.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.7 AMK76415.1 - 0.13 13.5 0.5 0.2 12.8 0.5 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2452 PF10504.9 AMK76416.1 - 2.4e-08 33.6 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) MerR_1 PF13411.6 AMK76418.1 - 3.6e-17 62.2 0.1 1.1e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AMK76418.1 - 4.2e-14 52.0 0.1 1e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 MerR family regulatory protein TipAS PF07739.13 AMK76418.1 - 2.9e-11 43.9 0.3 4.9e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 TipAS antibiotic-recognition domain MerR-DNA-bind PF09278.11 AMK76418.1 - 8.6e-09 35.8 6.9 3.2e-08 34.0 2.6 3.4 3 0 0 3 3 3 1 MerR, DNA binding HATPase_c PF02518.26 AMK76419.1 - 1.5e-18 67.3 0.0 2.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK76419.1 - 1.1e-11 44.6 0.3 2.7e-11 43.3 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 AMK76419.1 - 3.3e-10 40.1 0.0 6.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK76420.1 - 1.6e-15 56.4 0.2 2.2e-15 55.9 0.2 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AMK76420.1 - 3.5e-10 40.0 0.0 5.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AMK76420.1 - 0.00016 21.3 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AMK76420.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sperm_Ag_HE2 PF05324.13 AMK76421.1 - 0.042 14.3 0.0 0.058 13.9 0.0 1.2 1 0 0 1 1 1 0 Sperm antigen HE2 Cadherin_C_2 PF16492.5 AMK76421.1 - 0.07 13.9 0.1 0.074 13.8 0.1 1.3 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF2846 PF11008.8 AMK76422.1 - 0.0019 18.1 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) DUF1566 PF07603.11 AMK76425.1 - 2.2e-15 57.0 0.3 6.2e-15 55.6 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1566) PEP-CTERM PF07589.11 AMK76425.1 - 0.37 10.9 0.3 0.37 10.9 0.3 2.0 2 0 0 2 2 2 0 PEP-CTERM motif PGI PF00342.19 AMK76427.1 - 3.6e-233 774.5 0.1 4.2e-233 774.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase McrBC PF10117.9 AMK76427.1 - 0.15 11.1 0.1 0.29 10.2 0.1 1.4 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component Cu-oxidase_2 PF07731.14 AMK76429.1 - 0.00034 20.3 0.2 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase SoxE PF06525.11 AMK76429.1 - 0.065 12.7 0.2 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 Sulfocyanin (SoxE) domain MtrF PF09472.10 AMK76429.1 - 0.55 9.7 5.1 4.4 6.8 1.5 2.9 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SNARE_assoc PF09335.11 AMK76430.1 - 9.4e-08 32.6 3.7 9.4e-08 32.6 3.7 1.4 1 1 0 1 1 1 1 SNARE associated Golgi protein DUF1842 PF08896.10 AMK76430.1 - 0.074 13.3 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) DUF5357 PF17310.2 AMK76431.1 - 0.019 13.6 1.1 0.026 13.1 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) MOSC PF03473.17 AMK76432.1 - 3.6e-08 33.5 0.0 1.4e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 MOSC domain Host_attach PF10116.9 AMK76433.1 - 6.2e-41 140.2 0.4 6.9e-41 140.1 0.4 1.0 1 0 0 1 1 1 1 Protein required for attachment to host cells baeRF_family12 PF18856.1 AMK76433.1 - 1.5e-30 106.6 0.2 1.6e-30 106.5 0.2 1.0 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 12 baeRF_family10 PF18854.1 AMK76433.1 - 0.00043 20.5 1.1 0.00087 19.5 1.1 1.5 1 1 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 baeRF_family5 PF18846.1 AMK76433.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 tRNA-synt_1 PF00133.22 AMK76434.1 - 1.7e-210 700.3 0.1 2.1e-209 696.7 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AMK76434.1 - 6.7e-43 146.3 0.0 1.3e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 AMK76434.1 - 7.1e-18 64.6 5.4 1.4e-17 63.7 5.4 1.5 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 AMK76434.1 - 1.2e-16 60.5 5.0 1.7e-06 27.1 0.1 4.9 3 2 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 AMK76434.1 - 1.2e-07 31.5 0.0 9.3e-06 25.3 0.0 2.4 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 ABC_tran_CTD PF16326.5 AMK76434.1 - 0.0021 18.3 2.2 0.0021 18.3 2.2 2.1 2 0 0 2 2 2 1 ABC transporter C-terminal domain tRNA-synt_1e PF01406.19 AMK76434.1 - 0.0021 17.5 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 AMK76434.1 - 0.2 11.0 0.0 0.44 9.8 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) HDOD PF08668.12 AMK76435.1 - 4.6e-37 127.4 0.1 8e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 HDOD domain GAF PF01590.26 AMK76435.1 - 4.1e-05 24.2 0.0 7.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain DUF732 PF05305.14 AMK76435.1 - 0.0044 17.4 1.3 0.036 14.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF732) HD PF01966.22 AMK76435.1 - 0.0047 17.1 0.1 0.021 15.1 0.1 2.0 1 1 1 2 2 2 1 HD domain GAF_2 PF13185.6 AMK76435.1 - 0.0069 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.24 AMK76436.1 - 5.9e-43 145.6 0.1 2e-23 82.7 0.1 2.1 2 0 0 2 2 2 2 Response regulator receiver domain PAS_3 PF08447.12 AMK76437.1 - 2.9e-12 46.7 0.0 4.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AMK76437.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AMK76437.1 - 3.5e-06 27.2 0.0 6.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AMK76437.1 - 8.4e-05 22.8 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK76437.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 PAS domain MCPsignal PF00015.21 AMK76438.1 - 8.6e-32 110.3 17.5 1.3e-31 109.7 6.3 2.8 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain CZB PF13682.6 AMK76438.1 - 4.3e-10 39.9 0.3 1.1e-09 38.6 0.3 1.7 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain DUF1664 PF07889.12 AMK76438.1 - 0.0007 19.6 8.7 0.0072 16.4 1.4 3.0 3 0 0 3 3 2 1 Protein of unknown function (DUF1664) Sec34 PF04136.15 AMK76438.1 - 0.00073 19.4 6.5 0.037 13.9 0.4 3.1 2 1 1 3 3 3 2 Sec34-like family PilJ PF13675.6 AMK76438.1 - 0.0029 17.6 1.3 2.1 8.4 0.1 2.8 2 0 0 2 2 2 2 Type IV pili methyl-accepting chemotaxis transducer N-term APG17 PF04108.12 AMK76438.1 - 0.0052 16.0 10.4 0.077 12.1 10.5 2.2 1 1 1 2 2 2 1 Autophagy protein Apg17 DUF948 PF06103.11 AMK76438.1 - 0.0071 16.6 9.8 0.85 9.9 0.2 3.9 3 1 0 3 3 3 2 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 AMK76438.1 - 0.021 15.2 1.9 0.021 15.2 1.9 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Spectrin PF00435.21 AMK76438.1 - 0.039 14.4 5.8 0.54 10.8 0.6 2.7 2 1 1 3 3 3 0 Spectrin repeat TMP_2 PF06791.13 AMK76438.1 - 0.054 13.2 7.1 0.074 12.7 3.3 2.3 1 1 1 2 2 2 0 Prophage tail length tape measure protein DUF2605 PF10792.9 AMK76438.1 - 0.068 13.1 4.8 8.2 6.4 0.0 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF2605) PDE4_UCR PF18100.1 AMK76438.1 - 0.22 12.2 3.5 5.2 7.7 0.6 2.6 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) FUSC PF04632.12 AMK76438.1 - 0.49 8.9 4.1 4.4 5.7 0.1 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Gp-FAR-1 PF05823.12 AMK76438.1 - 0.57 10.5 5.5 0.21 12.0 1.0 2.3 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ZYG-11_interact PF05884.12 AMK76438.1 - 0.79 9.1 4.3 0.3 10.5 0.7 1.9 2 0 0 2 2 2 0 Interactor of ZYG-11 Laminin_II PF06009.12 AMK76438.1 - 1.4 8.9 15.2 2.1 8.4 4.7 2.9 1 1 2 3 3 3 0 Laminin Domain II Syntaxin PF00804.25 AMK76438.1 - 1.5 8.4 10.2 2.3 7.8 2.6 3.3 1 1 2 3 3 3 0 Syntaxin HIP1_clath_bdg PF16515.5 AMK76438.1 - 1.6 9.4 11.0 3 8.5 0.1 3.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ParB PF08775.10 AMK76438.1 - 3 8.3 7.4 1 9.9 1.4 2.8 2 1 0 2 2 2 0 ParB family Sec20 PF03908.13 AMK76438.1 - 7.5 6.5 13.3 0.31 11.0 2.2 3.3 3 1 0 3 3 3 0 Sec20 GldM_N PF12081.8 AMK76438.1 - 8.7 6.4 12.9 1.7 8.7 0.3 3.2 3 1 0 3 3 3 0 GldM N-terminal domain DPBB_1 PF03330.18 AMK76439.1 - 1.1e-25 89.8 0.0 1.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Gly-zipper_OmpA PF13436.6 AMK76440.1 - 1.8e-08 34.1 34.0 3.1e-08 33.2 34.0 1.4 1 0 0 1 1 1 1 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 AMK76440.1 - 1.1e-05 25.1 39.4 0.00017 21.3 31.4 2.2 1 1 1 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AMK76440.1 - 0.00038 20.4 39.5 0.00068 19.6 31.4 2.2 1 1 1 2 2 2 2 Glycine zipper TraT PF05818.12 AMK76440.1 - 0.025 14.2 4.4 0.03 14.0 4.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF3482 PF11981.8 AMK76440.1 - 0.047 13.1 7.9 0.055 12.9 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Sporozoite_P67 PF05642.11 AMK76440.1 - 0.23 9.5 3.9 0.25 9.4 3.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF726 PF05277.12 AMK76440.1 - 2.9 6.7 6.4 3.7 6.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF1269 PF06897.12 AMK76440.1 - 7.1 7.0 19.5 0.35 11.2 11.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 AMK76440.1 - 7.4 6.5 42.3 28 4.7 20.4 2.7 1 1 1 2 2 2 0 Glycine zipper 2TM domain Rick_17kDa_Anti PF05433.15 AMK76441.1 - 0.00043 20.1 8.7 0.00064 19.5 8.7 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 AMK76441.1 - 0.13 12.3 12.4 0.67 10.0 12.4 2.0 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 AMK76441.1 - 1.4 8.7 10.5 3.3 7.5 10.5 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Y1_Tnp PF01797.16 AMK76444.1 - 3.5e-08 33.6 0.8 4.5e-08 33.2 0.8 1.2 1 0 0 1 1 1 1 Transposase IS200 like Citrate_synt PF00285.21 AMK76445.1 - 1.8e-131 438.5 0.0 2.1e-131 438.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_tran_WecB PF03808.13 AMK76446.1 - 3.2e-58 196.4 0.1 4.2e-58 196.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Beta_helix PF13229.6 AMK76448.1 - 4.4e-17 62.4 48.5 3.4e-09 36.7 6.3 4.6 3 1 1 4 4 4 3 Right handed beta helix region NRBF2_MIT PF17169.4 AMK76448.1 - 0.2 11.9 0.0 0.48 10.7 0.0 1.5 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Beta_helix PF13229.6 AMK76449.1 - 4.2e-18 65.7 32.7 1.6e-07 31.3 15.0 3.8 2 1 1 4 4 4 3 Right handed beta helix region NosD PF05048.13 AMK76449.1 - 2.5e-05 23.7 29.6 0.00028 20.3 5.4 4.0 2 1 0 4 4 4 2 Periplasmic copper-binding protein (NosD) Methyltransf_11 PF08241.12 AMK76450.1 - 1.2e-10 41.8 0.0 2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76450.1 - 5e-07 30.3 0.0 7.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK76450.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 AMK76450.1 - 0.0002 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 AMK76450.1 - 0.00027 21.6 0.0 0.00045 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK76450.1 - 0.0038 17.0 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 AMK76450.1 - 0.055 12.0 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Glycos_transf_1 PF00534.20 AMK76451.1 - 1.6e-30 105.9 0.0 3.4e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK76451.1 - 4.2e-26 92.0 0.0 2.9e-25 89.2 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AMK76451.1 - 4.1e-13 49.5 0.0 6.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK76451.1 - 5.5e-13 49.3 0.0 1.5e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK76451.1 - 4.3e-10 40.3 0.0 8.2e-09 36.1 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AMK76451.1 - 0.00046 20.2 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 AMK76451.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain VRP3 PF03536.15 AMK76452.1 - 0.16 11.4 0.4 1 8.8 0.2 2.0 2 0 0 2 2 2 0 Salmonella virulence-associated 28kDa protein Glycos_transf_1 PF00534.20 AMK76453.1 - 3.6e-25 88.5 0.0 5.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK76453.1 - 8.5e-21 74.8 0.1 1.6e-20 73.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK76453.1 - 4.9e-06 26.7 0.1 1.5e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK76453.1 - 4.2e-05 24.0 0.1 0.00062 20.2 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AMK76453.1 - 0.00026 21.3 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 HK PF02110.15 AMK76453.1 - 0.015 14.7 0.1 0.033 13.6 0.1 1.5 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family Glyco_trans_1_4 PF13692.6 AMK76454.1 - 9.8e-12 45.5 0.0 2.5e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK76454.1 - 1.6e-11 44.1 0.0 2.4e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK76454.1 - 2e-06 27.9 0.0 4.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 HIRAN PF08797.11 AMK76454.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 HIRAN domain Wzy_C PF04932.15 AMK76455.1 - 1.1e-07 31.7 14.5 1.1e-07 31.7 14.5 4.0 1 1 2 3 3 3 1 O-Antigen ligase FixQ PF05545.11 AMK76455.1 - 0.0074 16.2 0.2 0.0074 16.2 0.2 5.1 6 1 0 6 6 6 1 Cbb3-type cytochrome oxidase component FixQ DUF1622 PF07784.11 AMK76455.1 - 0.085 12.8 2.3 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) Glycos_transf_2 PF00535.26 AMK76456.1 - 1.7e-23 83.3 0.4 2.5e-23 82.7 0.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK76456.1 - 9.6e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK76456.1 - 1.1e-05 25.1 2.2 0.00013 21.5 2.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AMK76456.1 - 2e-05 24.6 0.3 2.8e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AMK76456.1 - 0.0018 18.7 0.3 0.0038 17.7 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 AMK76456.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase INCENP_ARK-bind PF03941.15 AMK76456.1 - 0.062 13.2 3.6 0.094 12.7 0.0 2.6 2 1 1 3 3 3 0 Inner centromere protein, ARK binding region Glycos_transf_2 PF00535.26 AMK76457.1 - 4.1e-33 114.6 0.1 5.9e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK76457.1 - 2.1e-14 54.0 0.0 2.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK76457.1 - 4.5e-14 52.6 0.3 5.5e-14 52.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK76457.1 - 7.2e-06 26.4 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 MurJ PF03023.14 AMK76458.1 - 0.00038 19.2 14.0 0.00038 19.2 14.0 2.8 1 1 2 3 3 3 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AMK76458.1 - 0.0047 17.0 9.4 0.0047 17.0 9.4 4.6 1 1 4 5 5 5 1 Polysaccharide biosynthesis C-terminal domain VanZ PF04892.12 AMK76459.1 - 1.1e-10 42.2 4.2 3.6e-10 40.6 4.2 1.7 1 1 0 1 1 1 1 VanZ like family DUF2279 PF10043.9 AMK76459.1 - 0.032 15.0 0.1 0.053 14.3 0.1 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) DPM3 PF08285.11 AMK76459.1 - 2 8.6 6.6 2.3 8.5 3.7 2.3 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1657 PF07870.11 AMK76461.1 - 0.28 11.1 1.8 0.56 10.1 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1657) Bac_transf PF02397.16 AMK76462.1 - 1.3e-58 197.7 0.1 2e-58 197.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AMK76462.1 - 3.1e-32 112.0 0.4 6.9e-32 110.9 0.0 1.8 2 0 0 2 2 2 1 CoA-binding domain OMPdecase PF00215.24 AMK76463.1 - 2.1e-36 125.6 1.3 2.4e-36 125.4 1.3 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF559 PF04480.12 AMK76464.1 - 1.5e-42 143.9 0.7 1.8e-42 143.6 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 AMK76464.1 - 1.9e-12 47.2 0.2 2.4e-12 46.8 0.2 1.2 1 0 0 1 1 1 1 REase_MTES_1575 DUF2726 PF10881.8 AMK76464.1 - 0.006 16.5 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2726) EABR PF12180.8 AMK76464.1 - 0.11 12.2 3.8 0.22 11.2 3.8 1.6 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 SKI PF01202.22 AMK76465.1 - 1.7e-52 177.7 0.0 2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AMK76465.1 - 2e-07 31.6 0.0 3.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AMK76465.1 - 1.1e-05 25.6 0.0 0.00046 20.4 0.0 2.1 1 1 1 2 2 2 1 Cytidylate kinase-like family dNK PF01712.19 AMK76465.1 - 1.7e-05 24.8 0.1 0.024 14.5 0.0 2.3 2 1 0 2 2 2 2 Deoxynucleoside kinase AAA_33 PF13671.6 AMK76465.1 - 2.8e-05 24.3 0.1 0.00014 22.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 AMK76465.1 - 0.00028 21.3 0.0 0.0062 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AMK76465.1 - 0.0013 19.1 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AMK76465.1 - 0.011 16.1 0.1 0.034 14.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK76465.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AMK76465.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 AMK76465.1 - 0.041 13.6 0.1 0.8 9.4 0.0 2.5 2 1 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 AMK76465.1 - 0.057 13.7 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 AMK76465.1 - 0.058 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 AMK76465.1 - 0.072 12.8 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AMK76465.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) 6PF2K PF01591.18 AMK76465.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DHQ_synthase PF01761.20 AMK76466.1 - 4.1e-108 360.5 0.0 5.1e-108 360.2 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AMK76466.1 - 9.5e-14 51.7 1.2 7.7e-13 48.7 1.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AMK76466.1 - 1.6e-09 37.1 0.7 5.3e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_22 PF13401.6 AMK76467.1 - 1.8e-09 37.9 0.0 4.1e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain SPOR PF05036.13 AMK76467.1 - 1.4e-06 28.6 0.1 1.2e-05 25.6 0.2 2.2 2 0 0 2 2 2 1 Sporulation related domain ATPase_2 PF01637.18 AMK76467.1 - 4.4e-05 23.5 0.0 0.03 14.2 0.0 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AMK76467.1 - 0.00019 21.0 0.0 0.00069 19.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 AMK76467.1 - 0.00042 20.7 0.3 0.0042 17.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 AMK76467.1 - 0.0023 18.0 0.0 0.0057 16.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AMK76467.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AMK76467.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AMK76467.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 AMK76467.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase URO-D PF01208.17 AMK76468.1 - 8.4e-144 479.0 0.0 9.4e-144 478.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) XPC-binding PF09280.11 AMK76468.1 - 0.0042 16.8 0.5 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 XPC-binding domain UPF0047 PF01894.17 AMK76469.1 - 1.2e-37 128.6 0.0 1.3e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF411 PF04214.13 AMK76470.1 - 5e-32 109.7 0.5 6.7e-32 109.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF Thioredoxin_4 PF13462.6 AMK76470.1 - 0.1 12.8 0.1 1.8 8.7 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin Epimerase PF01370.21 AMK76471.1 - 1.6e-37 129.3 0.0 2e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AMK76471.1 - 1.4e-24 86.6 0.0 2.4e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 AMK76471.1 - 1.5e-21 77.2 0.0 9.8e-15 54.8 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AMK76471.1 - 1.7e-17 63.4 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 AMK76471.1 - 1.8e-16 60.1 0.1 5.4e-13 48.7 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 AMK76471.1 - 1.7e-10 41.1 0.1 4.8e-10 39.6 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 AMK76471.1 - 1.1e-08 34.6 0.6 1.8e-05 24.0 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.13 AMK76471.1 - 2.2e-06 27.4 0.1 0.0019 17.8 0.7 2.9 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 AMK76471.1 - 7.3e-05 22.7 1.5 0.043 13.7 0.1 2.2 1 1 1 2 2 2 2 KR domain adh_short PF00106.25 AMK76471.1 - 0.00087 18.8 0.1 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Glycos_transf_4 PF00953.21 AMK76472.1 - 7.9e-31 107.2 10.5 7.9e-31 107.2 10.5 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 Polysacc_synt_2 PF02719.15 AMK76473.1 - 1e-119 399.0 0.0 1.9e-119 398.1 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 AMK76473.1 - 4.7e-25 88.5 0.0 4e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CoA_binding_3 PF13727.6 AMK76473.1 - 7.1e-18 65.2 0.6 2.3e-17 63.6 0.2 2.1 2 1 0 2 2 2 1 CoA-binding domain GDP_Man_Dehyd PF16363.5 AMK76473.1 - 1.3e-15 57.7 0.0 2.5e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AMK76473.1 - 4.1e-15 55.6 0.0 8.1e-14 51.4 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AMK76473.1 - 2.9e-11 42.9 0.0 6.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AMK76473.1 - 2.4e-08 34.1 0.4 1.2e-07 31.8 0.1 2.3 3 1 0 3 3 2 1 NAD(P)H-binding adh_short PF00106.25 AMK76473.1 - 3.4e-06 26.7 0.1 8.3e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK76473.1 - 2.4e-05 24.3 0.1 5.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AMK76473.1 - 0.00031 21.0 0.1 0.66 10.2 0.0 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 AMK76473.1 - 0.00038 21.1 0.1 1.4 9.6 0.0 2.7 2 1 0 2 2 2 2 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 AMK76473.1 - 0.00052 20.3 0.6 1.8 8.9 0.1 3.0 2 1 1 3 3 3 2 TrkA-N domain NAD_binding_4 PF07993.12 AMK76473.1 - 0.0012 18.0 0.4 0.79 8.8 0.6 3.1 1 1 1 2 2 2 1 Male sterility protein ThiF PF00899.21 AMK76473.1 - 0.0021 17.5 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 ThiF family CoA_binding PF02629.19 AMK76473.1 - 0.004 17.8 0.1 0.013 16.1 0.0 1.8 2 0 0 2 2 1 1 CoA binding domain NmrA PF05368.13 AMK76473.1 - 0.013 15.1 0.2 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.20 AMK76473.1 - 0.019 15.1 0.0 7.8 6.6 0.0 3.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2967 PF11179.8 AMK76473.1 - 0.25 9.4 0.0 0.34 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DPM3 PF08285.11 AMK76473.1 - 2.9 8.2 9.0 6 7.1 1.5 2.5 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Methyltransf_4 PF02390.17 AMK76474.1 - 0.0027 17.2 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 AMK76474.1 - 0.053 13.1 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 AMK76474.1 - 0.072 13.8 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 AMK76474.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MotB_plug PF13677.6 AMK76475.1 - 5.5e-21 73.9 0.1 1e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AMK76475.1 - 1.9e-12 47.4 0.1 1.2e-11 44.8 0.0 2.4 3 0 0 3 3 3 1 OmpA family MotA_ExbB PF01618.16 AMK76476.1 - 4.1e-12 45.9 0.0 8.9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF1815 PF08844.10 AMK76476.1 - 0.086 12.8 0.1 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1815) Podoplanin PF05808.11 AMK76476.1 - 0.25 11.5 3.5 1.1 9.3 3.5 2.1 1 1 0 1 1 1 0 Podoplanin MMPL PF03176.15 AMK76477.1 - 7.6e-27 94.1 29.5 2.3e-21 76.1 6.3 3.4 3 1 0 3 3 3 2 MMPL family ACR_tran PF00873.19 AMK76477.1 - 1.3e-05 23.1 11.0 1.3e-05 23.1 11.0 3.0 3 1 0 3 3 3 2 AcrB/AcrD/AcrF family DUF1158 PF06643.11 AMK76477.1 - 2.2 8.9 9.7 0.67 10.5 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) Na_Ca_ex PF01699.24 AMK76478.1 - 2.5e-60 202.8 27.9 3e-35 121.4 7.2 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein BacA PF02673.18 AMK76479.1 - 6.8e-82 275.0 10.9 7.9e-82 274.8 10.9 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA DUF3784 PF12650.7 AMK76479.1 - 2.4 8.4 15.8 0.32 11.2 2.1 4.0 3 1 0 4 4 4 0 Domain of unknown function (DUF3784) AAA_33 PF13671.6 AMK76480.1 - 1.1e-30 106.7 0.0 1.8e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AMK76480.1 - 1.9e-07 30.5 0.0 3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin APH PF01636.23 AMK76480.1 - 1.3e-06 28.5 1.0 1.3e-06 28.5 1.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA_17 PF13207.6 AMK76480.1 - 0.00043 20.7 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AMK76480.1 - 0.0021 18.6 0.0 0.0068 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 AMK76480.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 AMK76480.1 - 0.033 14.3 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Torsin CPT PF07931.12 AMK76480.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 AMK76480.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 AMK76480.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 AMK76480.1 - 1.6 9.1 6.8 2.8 8.3 3.2 2.9 2 1 0 2 2 2 0 AAA ATPase domain ADH_N PF08240.12 AMK76481.1 - 5.1e-34 116.4 0.2 9.4e-34 115.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AMK76481.1 - 0.0061 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AMK76481.1 - 0.048 14.7 0.0 0.078 14.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Phage_integrase PF00589.22 AMK76482.1 - 0.086 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family DUF2490 PF10677.9 AMK76484.1 - 9.8e-41 139.8 5.7 1.2e-40 139.5 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) OmpA_membrane PF01389.17 AMK76484.1 - 0.00048 19.9 0.3 0.3 10.8 0.0 2.3 2 0 0 2 2 2 2 OmpA-like transmembrane domain OMP_b-brl PF13505.6 AMK76484.1 - 0.0034 17.5 6.4 0.051 13.7 6.4 2.2 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 AMK76484.1 - 0.0076 16.4 0.5 0.026 14.6 0.3 1.9 2 1 0 2 2 2 1 Opacity family porin protein Phenol_MetA_deg PF13557.6 AMK76484.1 - 0.012 15.6 4.0 0.85 9.5 0.1 2.5 1 1 1 2 2 2 0 Putative MetA-pathway of phenol degradation HupE_UreJ_2 PF13795.6 AMK76486.1 - 3.9e-49 166.3 5.2 5.7e-49 165.7 5.2 1.2 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ PF04955.12 AMK76486.1 - 2.6e-06 27.0 4.1 4.4e-06 26.3 4.1 1.3 1 0 0 1 1 1 1 HupE / UreJ protein Gram_pos_anchor PF00746.21 AMK76487.1 - 4.2 7.4 6.1 6.5 6.8 2.0 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif CopC PF04234.12 AMK76488.1 - 7.3e-25 87.8 0.3 8.6e-25 87.6 0.3 1.1 1 0 0 1 1 1 1 CopC domain SpaA PF17802.1 AMK76488.1 - 0.0067 16.7 0.2 0.0077 16.5 0.2 1.2 1 0 0 1 1 1 1 Prealbumin-like fold domain DUF5011 PF16403.5 AMK76488.1 - 0.011 15.8 0.3 0.017 15.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) Big_1 PF02369.16 AMK76488.1 - 0.014 15.4 0.2 0.026 14.5 0.2 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) BNR_2 PF13088.6 AMK76489.1 - 1.5e-17 63.8 5.4 1.4e-12 47.6 0.4 3.6 2 2 1 3 3 3 3 BNR repeat-like domain BNR PF02012.20 AMK76489.1 - 3.6e-09 35.2 16.2 0.15 12.1 0.1 6.9 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_4 PF15892.5 AMK76489.1 - 6.4e-05 22.4 0.8 0.21 10.9 0.1 3.9 2 2 1 3 3 3 2 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 AMK76489.1 - 0.0016 17.3 2.8 0.018 13.9 0.1 3.1 1 1 3 4 4 4 1 Sortilin, neurotensin receptor 3, HXXEE PF13787.6 AMK76490.1 - 8.5e-19 68.4 5.3 8.5e-19 68.4 5.3 1.8 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif HATPase_c PF02518.26 AMK76491.1 - 1.6e-19 70.4 0.0 7.3e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK76491.1 - 9.6e-13 48.0 1.3 2.8e-12 46.5 1.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain 2CSK_N PF08521.10 AMK76491.1 - 1.6e-10 41.3 3.5 5.7e-10 39.4 0.1 2.3 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HATPase_c_2 PF13581.6 AMK76491.1 - 0.00047 20.1 1.0 0.0012 18.8 0.1 2.2 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AMK76491.1 - 0.0008 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 GHKL domain TarH PF02203.15 AMK76491.1 - 0.025 14.5 6.5 0.33 10.8 0.0 3.0 3 0 0 3 3 3 0 Tar ligand binding domain homologue HAMP PF00672.25 AMK76491.1 - 0.07 13.5 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 HAMP domain PduV-EutP PF10662.9 AMK76491.1 - 0.086 12.6 0.0 0.32 10.8 0.0 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Response_reg PF00072.24 AMK76492.1 - 5.9e-27 94.1 0.0 8.2e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK76492.1 - 4.3e-22 78.0 0.1 7.7e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Iso_dh PF00180.20 AMK76493.1 - 6.1e-77 259.1 0.0 7.1e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GMC_oxred_C PF05199.13 AMK76494.1 - 9e-15 55.5 0.0 1.8e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 AMK76494.1 - 1.1e-11 44.7 0.0 1.2e-07 31.5 0.0 2.5 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 AMK76494.1 - 0.0031 17.7 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 AMK76494.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 AMK76495.1 - 1.3e-05 25.9 3.0 2.6e-05 25.0 3.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AMK76495.1 - 4.8e-05 23.1 0.6 0.11 12.1 0.3 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold MarR_2 PF12802.7 AMK76497.1 - 1.1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AMK76497.1 - 9.5e-06 26.0 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 AMK76497.1 - 0.00023 20.9 0.0 0.00048 19.9 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AMK76497.1 - 0.00077 19.4 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AMK76497.1 - 0.0028 17.8 0.3 0.017 15.3 0.1 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AMK76497.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 AMK76497.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Sigma70_r4 PF04545.16 AMK76497.1 - 0.026 14.0 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Fe_dep_repress PF01325.19 AMK76497.1 - 0.027 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Crp PF00325.20 AMK76497.1 - 0.037 13.7 0.1 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_1 PF00126.27 AMK76497.1 - 0.04 13.9 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF2513 PF10711.9 AMK76497.1 - 0.085 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) HTH_5 PF01022.20 AMK76497.1 - 0.09 12.7 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family BMFP PF04380.13 AMK76498.1 - 5.9e-31 106.8 1.4 6.5e-31 106.6 1.4 1.0 1 0 0 1 1 1 1 Membrane fusogenic activity HSBP1 PF06825.12 AMK76498.1 - 0.028 14.2 0.2 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Gal4_dimer PF03902.13 AMK76498.1 - 0.046 13.9 1.9 0.054 13.7 1.0 1.6 2 0 0 2 2 2 0 Gal4-like dimerisation domain Phasin PF05597.11 AMK76498.1 - 0.055 13.5 1.3 0.14 12.1 1.3 1.7 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Trimer_CC PF08954.11 AMK76498.1 - 0.13 11.8 4.2 0.32 10.6 4.2 1.8 1 1 0 1 1 1 0 Trimerisation motif Sugarporin_N PF11471.8 AMK76498.1 - 0.15 12.1 3.8 0.24 11.4 3.8 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Matrilin_ccoil PF10393.9 AMK76498.1 - 0.47 10.4 3.2 0.92 9.4 0.8 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Nuc_deoxyrib_tr PF05014.15 AMK76500.1 - 4e-16 59.2 0.0 6.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase PfkB PF00294.24 AMK76500.1 - 2.5e-09 36.8 0.0 4.8e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Nuc_deoxyri_tr2 PF15891.5 AMK76500.1 - 1.5e-05 25.3 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like LDcluster4 PF18306.1 AMK76500.1 - 0.0069 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 SLOG cluster4 family TrkA_N PF02254.18 AMK76500.1 - 0.17 12.2 0.0 0.84 9.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain QueC PF06508.13 AMK76501.1 - 1.8e-23 83.2 0.0 3.4e-23 82.3 0.0 1.4 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AMK76501.1 - 0.00084 19.1 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase Sulfotransfer_3 PF13469.6 AMK76501.1 - 0.18 12.2 0.0 0.43 10.9 0.0 1.6 2 0 0 2 2 2 0 Sulfotransferase family HHH PF00633.23 AMK76502.1 - 0.033 14.1 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif MethyltransfD12 PF02086.15 AMK76503.1 - 2.8e-08 33.8 0.3 0.002 17.8 0.2 2.3 1 1 1 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Peptidase_M78 PF06114.13 AMK76504.1 - 5.4e-07 29.6 0.2 1.1e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 IrrE N-terminal-like domain Exo_endo_phos_2 PF14529.6 AMK76504.1 - 0.04 13.8 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase PrpR_N PF06506.11 AMK76504.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Propionate catabolism activator HTH_19 PF12844.7 AMK76505.1 - 1.3e-09 38.0 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AMK76505.1 - 1.2e-06 28.7 0.1 5.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AMK76505.1 - 0.0047 17.0 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 AMK76505.1 - 0.05 13.5 0.4 0.16 11.9 0.6 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain Acetyltransf_10 PF13673.7 AMK76506.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK76506.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family RHH_1 PF01402.21 AMK76507.1 - 0.00033 20.5 0.2 0.00062 19.6 0.1 1.5 1 1 0 1 1 1 1 Ribbon-helix-helix protein, copG family FlhD PF05247.13 AMK76509.1 - 0.059 13.6 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) Prok-JAB PF14464.6 AMK76510.1 - 0.00012 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ThiF PF00899.21 AMK76511.1 - 4.1e-08 32.9 0.0 3.3e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 ThiF family DUF3487 PF11990.8 AMK76512.1 - 0.7 9.8 3.9 3 7.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Exosortase_EpsH PF09721.10 AMK76513.1 - 6.2e-09 35.8 10.9 9.4e-09 35.2 10.9 1.3 1 1 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) DUF4227 PF14004.6 AMK76513.1 - 1.1 9.3 5.2 14 5.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF3021 PF11457.8 AMK76513.1 - 5.3 7.4 13.6 1.5 9.1 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) Imm1 PF14430.6 AMK76514.1 - 0.0016 19.1 0.0 0.002 18.8 0.0 1.1 1 0 0 1 1 1 1 Immunity protein Imm1 MTABC_N PF16185.5 AMK76515.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region ComJ PF11033.8 AMK76516.1 - 2.8e-19 69.0 0.0 3.7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Competence protein J (ComJ) Prenyltrans PF00432.21 AMK76517.1 - 4.8e-11 42.2 0.2 0.014 15.2 0.0 4.1 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 AMK76517.1 - 1.6e-07 30.8 8.6 0.0011 18.2 0.2 3.4 2 2 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain He_PIG PF05345.12 AMK76517.1 - 5.5e-06 26.5 0.5 5.5e-06 26.5 0.5 2.7 4 0 0 4 4 4 1 Putative Ig domain SQHop_cyclase_N PF13249.6 AMK76517.1 - 0.029 13.5 7.3 0.36 9.9 0.1 3.9 4 1 0 4 4 4 0 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 AMK76517.1 - 0.065 12.3 2.7 2.9 6.8 0.1 3.5 2 2 1 3 3 3 0 A-macroglobulin TED domain DNase_NucA_NucB PF14040.6 AMK76518.1 - 3.7e-13 49.9 0.0 4.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Glyco_hydro_63 PF03200.16 AMK76521.1 - 1e-09 37.7 0.8 2.6e-06 26.5 0.1 4.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain Chordopox_A20R PF05941.13 AMK76522.1 - 0.044 12.8 0.9 1.5 7.7 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus A20R protein Molybdopterin PF00384.22 AMK76525.1 - 3.2e-55 187.8 0.1 5.8e-55 187.0 0.1 1.5 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AMK76525.1 - 1.3e-14 54.2 0.0 2.8e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AMK76525.1 - 1.7e-12 47.1 0.8 3.1e-12 46.3 0.8 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Mob_synth_C PF06463.13 AMK76526.1 - 6.5e-31 106.9 0.0 1e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 AMK76526.1 - 6.4e-18 65.7 0.2 1.3e-17 64.7 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AMK76526.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK76526.1 - 0.063 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain DDE_Tnp_1_5 PF13737.6 AMK76527.1 - 3.1e-40 137.0 0.0 5.4e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76527.1 - 6.7e-25 88.0 0.3 8.3e-25 87.7 0.3 1.1 1 0 0 1 1 1 1 Transposase DDE domain Lipase_3 PF01764.25 AMK76529.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 AMK76529.1 - 0.15 11.5 0.0 0.56 9.6 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family MoeA_N PF03453.17 AMK76530.1 - 7.5e-40 136.3 0.0 1.1e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AMK76530.1 - 8.7e-29 100.0 0.0 1.6e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AMK76530.1 - 3.3e-16 59.2 0.0 6.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) AAA PF00004.29 AMK76532.1 - 5.7e-14 52.7 0.0 8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AMK76532.1 - 1.7e-05 24.8 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 AMK76532.1 - 0.00016 22.0 0.1 0.00046 20.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AMK76532.1 - 0.00072 18.9 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 AMK76532.1 - 0.003 17.9 0.2 0.024 15.0 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AMK76532.1 - 0.0038 17.0 0.2 0.0056 16.4 0.2 1.2 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AMK76532.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AMK76532.1 - 0.042 13.4 0.5 0.51 9.9 0.0 2.4 1 1 1 2 2 2 0 AAA domain DnaB_C PF03796.15 AMK76532.1 - 0.057 12.7 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Chorion_S16 PF05836.12 AMK76532.1 - 0.06 13.6 0.0 0.34 11.2 0.0 2.1 2 1 0 2 2 2 0 Chorion protein S16 AAA_5 PF07728.14 AMK76532.1 - 0.081 12.9 0.1 0.19 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_Mx PF15887.5 AMK76532.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase SMODS PF18144.1 AMK76533.1 - 5.8e-08 33.1 0.0 9.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NTP_transf_2 PF01909.23 AMK76533.1 - 0.00089 19.5 0.1 0.0028 17.9 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AMK76533.1 - 0.0038 17.3 0.0 0.0093 16.0 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase BCCT PF02028.17 AMK76534.1 - 0.014 13.9 4.6 0.017 13.6 4.6 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter DUF2162 PF09930.9 AMK76534.1 - 0.017 14.6 2.0 0.018 14.4 2.0 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DctQ PF04290.12 AMK76534.1 - 0.033 14.1 6.2 0.037 13.9 6.2 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_Dp1 PF16938.5 AMK76534.1 - 0.072 13.3 1.2 0.072 13.3 1.2 1.8 1 1 1 2 2 2 0 Putative phage holin Dp-1 DUF2852 PF11014.8 AMK76534.1 - 0.69 10.1 3.8 0.21 11.8 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) WYL PF13280.6 AMK76535.1 - 3.1e-09 37.1 0.0 4.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 WYL domain AAA PF00004.29 AMK76536.1 - 5.2e-13 49.6 0.0 9.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK76536.1 - 1.3e-05 25.2 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK76536.1 - 7.9e-05 23.1 0.1 0.0023 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AMK76536.1 - 0.0029 17.9 0.0 0.31 11.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AMK76536.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.9 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 AMK76536.1 - 0.011 15.7 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 AMK76536.1 - 0.012 15.7 0.2 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 AMK76536.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 AMK76536.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_7 PF12775.7 AMK76536.1 - 0.026 14.0 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 AMK76536.1 - 0.027 14.2 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 AMK76536.1 - 0.2 11.6 0.0 25 4.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 AMK76536.1 - 0.2 11.6 0.1 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 NTPase DUF4357 PF14267.6 AMK76536.1 - 0.72 9.8 2.5 4.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Metallophos PF00149.28 AMK76537.1 - 8.1e-08 33.0 0.3 1.1e-07 32.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK76537.1 - 0.00025 21.3 0.0 0.00045 20.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AMK76537.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Thioredoxin_16 PF18569.1 AMK76538.1 - 0.02 15.0 0.2 0.037 14.1 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin-like domain Metallophos PF00149.28 AMK76539.1 - 4e-14 53.6 0.1 5.9e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK76539.1 - 5.5e-05 23.4 0.0 9.1e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 AMK76539.1 - 0.12 10.6 0.1 0.24 9.6 0.0 1.4 1 1 1 2 2 2 0 Firmicute fructose-1,6-bisphosphatase TniB PF05621.11 AMK76542.1 - 2.5e-60 203.1 0.0 3.2e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AMK76542.1 - 3e-10 40.5 0.1 1.3e-09 38.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK76542.1 - 0.0011 19.4 0.1 0.0046 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AMK76542.1 - 0.011 15.7 0.0 0.6 10.0 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 AMK76542.1 - 0.028 13.8 0.0 0.074 12.4 0.0 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family ATPase PF06745.13 AMK76542.1 - 0.043 13.2 0.0 21 4.4 0.0 3.0 3 0 0 3 3 3 0 KaiC rve PF00665.26 AMK76543.1 - 4.2e-15 56.0 0.0 2.4e-14 53.5 0.0 2.4 1 1 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AMK76543.1 - 2.4e-14 53.0 0.0 4.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Mu transposase, C-terminal HTH_29 PF13551.6 AMK76543.1 - 3.1e-06 27.1 0.0 8.5e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 AMK76543.1 - 1.1e-05 25.9 1.1 3.1e-05 24.5 0.6 2.2 1 1 0 1 1 1 1 Homeodomain-like domain rve_3 PF13683.6 AMK76543.1 - 0.0011 18.7 0.1 0.085 12.6 0.0 3.2 3 0 0 3 3 3 1 Integrase core domain HTH_23 PF13384.6 AMK76543.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AMK76543.1 - 0.017 15.2 1.0 0.11 12.7 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Tn7_Tnp_TnsA_N PF08722.11 AMK76544.1 - 6.9e-16 58.2 0.6 1.4e-15 57.2 0.6 1.5 1 0 0 1 1 1 1 TnsA endonuclease N terminal Tn7_Tnp_TnsA_C PF08721.11 AMK76544.1 - 8.6e-07 29.5 0.1 1.9e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 TnsA endonuclease C terminal OEP PF02321.18 AMK76545.1 - 2.3e-33 115.6 14.6 6.5e-17 61.9 0.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein CwsA PF10814.8 AMK76545.1 - 0.028 14.6 0.7 0.028 14.6 0.7 2.0 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA TBCC_N PF16752.5 AMK76545.1 - 0.19 12.2 3.1 0.14 12.6 0.8 2.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HalX PF08663.10 AMK76545.1 - 8.9 6.7 10.3 3 8.3 0.2 4.1 4 0 0 4 4 4 0 HalX domain ACR_tran PF00873.19 AMK76546.1 - 1.6e-255 850.5 3.7 1.8e-255 850.3 3.7 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family HlyD_D23 PF16576.5 AMK76547.1 - 9.5e-31 106.7 2.2 1.3e-30 106.3 2.2 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76547.1 - 5e-18 65.8 5.7 1.2e-13 51.7 0.2 2.7 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AMK76547.1 - 6.4e-06 25.9 7.4 0.002 17.9 0.2 3.8 4 1 0 4 4 4 2 Biotin-requiring enzyme HlyD PF00529.20 AMK76547.1 - 1.3e-05 25.0 2.8 0.0014 18.5 1.0 3.5 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AMK76547.1 - 5.3e-05 23.0 1.4 5.3e-05 23.0 1.4 3.1 3 0 0 3 3 3 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 AMK76547.1 - 0.08 13.2 0.2 0.71 10.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 GCV_H PF01597.19 AMK76547.1 - 0.18 11.7 0.3 8.2 6.3 0.2 2.4 2 0 0 2 2 2 0 Glycine cleavage H-protein OEP PF02321.18 AMK76547.1 - 1 9.2 6.0 1.5 8.6 6.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein AhpC-TSA PF00578.21 AMK76548.1 - 2.3e-32 111.5 0.0 2.9e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK76548.1 - 2.9e-16 59.5 0.0 3.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 AMK76548.1 - 6.5e-11 41.9 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AP2 PF00847.20 AMK76549.1 - 8.6e-05 22.7 5.1 0.019 15.2 1.5 2.9 2 1 0 2 2 2 2 AP2 domain QRPTase_C PF01729.19 AMK76550.1 - 6.1e-57 192.1 0.4 8e-57 191.7 0.4 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AMK76550.1 - 1.8e-26 92.0 0.0 6.8e-26 90.1 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Amidase_2 PF01510.25 AMK76551.1 - 2.9e-27 95.6 0.0 4e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Dynamin_N PF00350.23 AMK76552.1 - 2.4e-13 50.5 0.9 7e-13 49.0 0.0 2.3 3 1 0 3 3 3 1 Dynamin family TMF_TATA_bd PF12325.8 AMK76552.1 - 0.038 14.2 0.5 0.038 14.2 0.5 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 AMK76552.1 - 0.12 12.6 2.4 20 5.5 0.0 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DASH_Dam1 PF08653.10 AMK76552.1 - 0.27 11.0 1.5 0.87 9.4 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 TbpB_B_D PF01298.18 AMK76552.1 - 0.28 11.6 1.8 0.24 11.8 0.3 1.7 2 0 0 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B PglZ PF08665.12 AMK76552.1 - 0.31 11.1 4.1 0.79 9.8 0.0 2.9 2 1 0 2 2 2 0 PglZ domain Pribosyltran PF00156.27 AMK76553.1 - 1.1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PA PF02225.22 AMK76553.1 - 0.034 14.2 0.1 0.05 13.6 0.1 1.3 1 0 0 1 1 1 0 PA domain Radical_SAM PF04055.21 AMK76554.1 - 9e-18 65.2 0.0 1.4e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 AMK76554.1 - 1.8e-10 40.7 0.0 4.4e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 HemN C-terminal domain HTH_45 PF14947.6 AMK76554.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix zf-H2C2_5 PF13909.6 AMK76554.1 - 1.5 8.6 3.4 0.9 9.4 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Glyoxalase PF00903.25 AMK76555.1 - 3.5e-14 53.1 0.0 5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 AMK76555.1 - 1.1e-08 35.3 0.0 1.9e-07 31.3 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AMK76555.1 - 0.00026 21.7 0.0 0.00035 21.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 AMK76555.1 - 0.012 15.7 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain CheR PF01739.18 AMK76556.1 - 1.3e-56 191.2 0.0 2e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AMK76556.1 - 2.3e-16 59.3 0.2 4.1e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 AMK76556.1 - 8.6e-09 36.0 0.0 2.4e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76556.1 - 1.6e-07 31.9 0.0 0.0016 19.1 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 AMK76556.1 - 7.5e-07 29.7 0.0 1.6e-05 25.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK76556.1 - 2.5e-06 27.4 0.0 0.00051 19.9 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 AMK76556.1 - 4.2e-06 26.7 0.0 6.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 AMK76556.1 - 0.006 16.0 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein MCPsignal PF00015.21 AMK76557.1 - 4.7e-37 127.4 44.3 1.7e-35 122.4 19.4 4.7 3 2 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AMK76557.1 - 2e-23 82.9 0.0 2e-23 82.9 0.0 4.3 3 1 0 4 4 4 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 AMK76557.1 - 1.7e-20 73.7 0.1 1.7e-20 73.7 0.1 4.3 4 0 0 4 4 4 1 Tar ligand binding domain homologue HAMP PF00672.25 AMK76557.1 - 3.3e-08 33.8 12.0 1.9e-07 31.3 0.0 5.2 5 0 0 5 5 5 1 HAMP domain DUF4335 PF14233.6 AMK76557.1 - 0.0062 16.5 0.9 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4335) Mur_ligase_C PF02875.21 AMK76557.1 - 0.0093 16.2 0.1 0.04 14.2 0.1 2.1 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF948 PF06103.11 AMK76557.1 - 0.011 15.9 0.5 0.011 15.9 0.5 5.4 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 AMK76557.1 - 0.33 11.4 19.2 0.38 11.2 2.1 3.4 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 AMK76557.1 - 0.62 10.2 6.7 2.7 8.1 0.2 3.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 AMK76557.1 - 0.91 8.5 5.9 9 5.3 0.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 AMK76557.1 - 2.2 7.1 8.6 2.1 7.2 2.1 2.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 CheW PF01584.19 AMK76558.1 - 1.8e-34 118.3 0.3 2.2e-34 118.1 0.3 1.1 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AMK76559.1 - 5.8e-21 74.6 0.3 1.3e-20 73.5 0.3 1.6 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AMK76559.1 - 5.3e-19 68.3 0.2 4.2e-18 65.4 0.0 2.6 2 0 0 2 2 2 1 Hpt domain HATPase_c PF02518.26 AMK76559.1 - 4.1e-17 62.7 0.0 1.1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AMK76559.1 - 1.3e-07 31.9 1.1 1.3e-07 31.9 1.1 3.0 4 1 0 4 4 4 1 Signal transducing histidine kinase, homodimeric domain HTH_9 PF08221.11 AMK76559.1 - 0.098 12.8 0.0 3 8.0 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain STAS_2 PF13466.6 AMK76560.1 - 9.1e-13 48.4 0.1 1e-12 48.2 0.1 1.0 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AMK76560.1 - 4e-05 23.2 0.1 4.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 STAS domain DUF2407 PF10302.9 AMK76560.1 - 0.019 15.5 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Response_reg PF00072.24 AMK76561.1 - 5.1e-27 94.2 0.0 5.7e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PRR20 PF15708.5 AMK76561.1 - 0.033 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 MCPsignal PF00015.21 AMK76562.1 - 1e-25 90.5 13.8 1e-25 90.5 13.8 1.9 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ALIX_LYPXL_bnd PF13949.6 AMK76562.1 - 2.7e-05 23.6 2.8 4.3e-05 23.0 2.8 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Apolipoprotein PF01442.18 AMK76562.1 - 0.0008 19.3 6.8 0.51 10.2 2.5 2.7 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain CheZ PF04344.13 AMK76562.1 - 0.0032 17.4 5.2 0.044 13.7 4.6 2.4 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ DUF4559 PF15112.6 AMK76562.1 - 0.0044 16.7 0.8 0.15 11.7 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4559) Phe_tRNA-synt_N PF02912.18 AMK76562.1 - 0.031 14.2 0.9 0.41 10.6 0.8 2.9 3 0 0 3 3 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain ApoLp-III PF07464.11 AMK76562.1 - 0.032 14.3 9.2 5.3 7.1 0.0 3.4 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) YojJ PF10372.9 AMK76562.1 - 0.048 13.7 1.3 0.52 10.4 0.0 3.1 3 1 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus V_ATPase_I PF01496.19 AMK76562.1 - 0.049 11.6 1.8 0.06 11.3 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 AMK76562.1 - 0.057 13.5 13.6 0.48 10.5 0.8 3.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BST2 PF16716.5 AMK76562.1 - 0.1 13.2 1.5 5.2 7.7 0.1 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 GIT1_C PF12205.8 AMK76562.1 - 0.11 12.6 5.4 0.18 11.9 0.5 3.0 2 1 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Tht1 PF04163.12 AMK76562.1 - 0.11 11.2 1.6 0.18 10.5 0.3 1.8 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein DASH_Duo1 PF08651.10 AMK76562.1 - 0.13 12.0 3.9 3.3 7.5 0.3 3.9 4 1 1 5 5 5 0 DASH complex subunit Duo1 DUF148 PF02520.17 AMK76562.1 - 0.25 11.5 7.3 0.15 12.2 0.5 3.2 2 2 1 3 3 3 0 Domain of unknown function DUF148 Mce4_CUP1 PF11887.8 AMK76562.1 - 0.33 10.4 2.1 13 5.2 0.2 2.4 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative CHASE3 PF05227.13 AMK76562.1 - 5.5 6.9 8.8 22 4.9 1.9 3.3 2 1 2 4 4 4 0 CHASE3 domain DUF2063 PF09836.9 AMK76564.1 - 4.3e-26 91.0 0.7 1.3e-25 89.4 0.6 1.9 2 0 0 2 2 2 1 Putative DNA-binding domain DUF692 PF05114.13 AMK76565.1 - 1.5e-102 342.3 0.0 1.7e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) AP_endonuc_2 PF01261.24 AMK76565.1 - 0.00029 20.3 0.5 0.00054 19.5 0.5 1.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel SNARE_assoc PF09335.11 AMK76566.1 - 5.7e-19 68.8 4.6 5.7e-19 68.8 4.6 1.7 2 1 0 2 2 2 1 SNARE associated Golgi protein HhH-GPD PF00730.25 AMK76568.1 - 3.2e-20 72.6 0.0 4.4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AMK76568.1 - 5e-07 29.3 0.1 1.3e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AMK76568.1 - 0.0002 21.6 9.5 0.00032 21.0 9.5 1.3 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III SMBP PF16785.5 AMK76569.1 - 1e-35 122.3 21.3 1.1e-35 122.2 21.3 1.0 1 0 0 1 1 1 1 Small metal-binding protein ANAPC5 PF12862.7 AMK76569.1 - 0.021 14.8 1.4 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF2564 PF10819.8 AMK76569.1 - 0.43 11.0 5.2 0.44 11.0 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) DUF4148 PF13663.6 AMK76569.1 - 0.67 10.2 5.5 1.2 9.4 5.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) DUF4398 PF14346.6 AMK76569.1 - 1 10.0 7.2 21 5.8 7.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) Thymidylat_synt PF00303.19 AMK76570.1 - 6e-107 356.7 0.0 6.9e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF4124 PF13511.6 AMK76571.1 - 5.2e-07 29.9 0.3 1.2e-06 28.7 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) EMC3_TMCO1 PF01956.16 AMK76571.1 - 7.8 6.2 5.7 12 5.6 5.7 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like adh_short PF00106.25 AMK76572.1 - 3.5e-40 137.6 0.0 4.7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AMK76572.1 - 2e-28 99.6 0.0 2.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AMK76572.1 - 6.2e-08 32.8 0.0 9.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 AMK76572.1 - 2.3e-06 27.2 0.0 4.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 AMK76572.1 - 3.7e-06 26.6 0.0 7.7e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AMK76572.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 AMK76572.1 - 0.095 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_C8 PF03569.13 AMK76573.1 - 0.012 15.2 1.0 0.04 13.5 0.3 1.8 1 1 1 2 2 2 0 Peptidase family C8 Arc_PepC PF06819.11 AMK76573.1 - 0.042 14.0 0.3 0.059 13.5 0.3 1.4 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain YabA PF06156.13 AMK76573.1 - 0.044 14.4 0.8 0.051 14.2 0.8 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ASFV_360 PF01671.16 AMK76574.1 - 0.016 14.7 0.1 0.025 14.1 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein Rsd_AlgQ PF04353.13 AMK76575.1 - 7.3e-35 120.1 0.5 8.7e-35 119.9 0.5 1.0 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ UPF0182 PF03699.13 AMK76576.1 - 3.6e-225 749.6 15.7 4.4e-225 749.3 15.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) PH_3 PF14593.6 AMK76576.1 - 0.016 15.3 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 PH domain Cu-oxidase_3 PF07732.15 AMK76577.1 - 5e-27 94.3 4.7 9.6e-27 93.4 0.4 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AMK76577.1 - 3.3e-22 78.7 6.0 2.4e-19 69.5 0.3 3.2 2 1 0 2 2 2 2 Multicopper oxidase TAT_signal PF10518.9 AMK76577.1 - 0.00041 20.1 0.6 0.00041 20.1 0.6 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence DUF3601 PF12208.8 AMK76577.1 - 0.097 12.8 0.2 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) Cu-oxidase_3 PF07732.15 AMK76578.1 - 3.6e-22 78.6 1.2 7.4e-15 55.0 0.9 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 AMK76578.1 - 2.5e-17 62.9 4.3 3.1e-12 46.4 1.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 AMK76578.1 - 0.00018 21.7 0.0 0.00064 19.9 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_17 PF00332.18 AMK76579.1 - 7.5e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 GGDEF PF00990.21 AMK76581.1 - 8.3e-45 152.4 2.9 2.7e-44 150.8 0.0 2.8 3 0 0 3 3 3 1 Diguanylate cyclase, GGDEF domain Darcynin PF17074.5 AMK76581.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Darcynin, domain of unknown function Entericidin PF08085.11 AMK76581.1 - 0.29 11.2 1.4 0.6 10.2 0.2 2.1 2 0 0 2 2 2 0 Entericidin EcnA/B family FliD_N PF02465.18 AMK76581.1 - 0.67 10.7 5.5 0.54 11.0 0.8 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus T2SSF PF00482.23 AMK76581.1 - 1.4 8.8 8.9 0.16 12.0 0.4 2.8 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F GGDEF PF00990.21 AMK76582.1 - 2e-46 157.7 1.4 2.9e-46 157.1 0.0 2.1 3 0 0 3 3 3 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AMK76582.1 - 0.0005 20.3 0.0 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 GGDEF-like domain CALCOCO1 PF07888.11 AMK76582.1 - 0.03 13.2 19.5 0.058 12.3 19.5 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GRDA PF04723.14 AMK76582.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A GvpL_GvpF PF06386.11 AMK76582.1 - 0.08 12.9 12.2 0.37 10.7 8.2 2.9 2 1 1 3 3 3 0 Gas vesicle synthesis protein GvpL/GvpF TSNAXIP1_N PF15739.5 AMK76582.1 - 5.8 7.3 16.7 0.11 12.9 0.8 3.2 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus DSBA PF01323.20 AMK76583.1 - 4.9e-18 65.6 1.7 1.9e-14 53.9 0.1 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 AMK76583.1 - 3.4e-10 40.3 0.0 4.3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 AMK76583.1 - 2.1e-05 24.5 0.2 0.013 15.5 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 AMK76583.1 - 0.00028 20.9 0.0 0.057 13.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain DUF953 PF06110.11 AMK76583.1 - 0.0035 17.0 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF953) DBI_PRT PF02277.17 AMK76583.1 - 0.032 13.5 0.2 0.052 12.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyltransferase Cytochrom_C PF00034.21 AMK76584.1 - 3.3e-15 57.0 5.9 8.3e-08 33.3 0.1 3.1 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AMK76584.1 - 3.1e-14 53.0 1.7 3.1e-06 27.4 0.1 2.4 2 1 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DUF3365 PF11845.8 AMK76584.1 - 0.00089 19.6 1.7 0.061 13.6 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3365) CCP_MauG PF03150.14 AMK76584.1 - 0.0028 18.3 0.1 3.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Di-haem cytochrome c peroxidase Paired_CXXCH_1 PF09699.10 AMK76584.1 - 0.0063 16.2 3.7 1.4 8.7 0.3 2.5 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_c3_2 PF14537.6 AMK76584.1 - 0.0084 16.6 0.2 5.1 7.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c3 DUF1924 PF09086.11 AMK76584.1 - 0.011 16.1 4.3 2.1 8.8 1.7 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrome_C7 PF14522.6 AMK76584.1 - 0.013 15.5 1.8 3.2 7.8 0.1 2.5 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 AMK76584.1 - 0.046 14.1 0.9 10 6.5 0.1 2.3 2 0 0 2 2 2 0 Class III cytochrome C family PSCyt1 PF07635.11 AMK76584.1 - 2.9 8.6 4.8 30 5.3 0.4 2.8 2 0 0 2 2 2 0 Planctomycete cytochrome C MMR_HSR1 PF01926.23 AMK76585.1 - 2.4e-18 66.3 0.0 4.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AMK76585.1 - 1.3e-06 28.4 0.0 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 AMK76585.1 - 6.2e-06 26.4 0.0 0.022 14.8 0.1 2.2 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 AMK76585.1 - 1.4e-05 24.6 0.0 2.7e-05 23.8 0.0 1.5 1 1 1 2 2 2 1 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 AMK76585.1 - 0.038 13.3 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRPRB PF09439.10 AMK76585.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HMD PF03201.16 AMK76585.1 - 0.091 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase AIG1 PF04548.16 AMK76585.1 - 0.096 12.0 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 AIG1 family AAA_21 PF13304.6 AMK76586.1 - 2e-19 70.5 2.1 3.8e-14 53.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AMK76586.1 - 2.2e-18 67.2 2.4 7.6e-13 48.9 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AMK76586.1 - 9.8e-06 25.2 0.2 0.00071 19.1 0.1 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK76586.1 - 0.0057 17.2 0.3 0.014 15.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 AMK76586.1 - 0.057 12.1 0.0 0.15 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF772 PF05598.11 AMK76587.1 - 2e-26 91.8 0.1 4.4e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK76587.1 - 4.6e-23 81.8 2.0 7.7e-23 81.1 2.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76587.1 - 4.3e-11 42.9 0.0 2.2e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 Transposase DDE domain Pkinase PF00069.25 AMK76588.1 - 2.2e-36 125.6 0.0 3.1e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AMK76588.1 - 7.1e-18 64.8 0.0 6.6e-17 61.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase dCache_1 PF02743.18 AMK76588.1 - 3.5e-13 49.9 0.0 6.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cache domain APH PF01636.23 AMK76588.1 - 2.4e-06 27.7 1.1 9.7e-06 25.7 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 AMK76588.1 - 0.063 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PAS_8 PF13188.7 AMK76588.1 - 0.15 12.1 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 PAS domain Rdx PF10262.9 AMK76589.1 - 1.3e-33 115.0 0.1 1.4e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 Rdx family Mur_ligase_M PF08245.12 AMK76590.1 - 1.5e-24 87.1 0.0 2.2e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 AMK76590.1 - 2.8e-16 59.6 0.0 7e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 AMK76590.1 - 1.9e-11 44.1 0.0 6.3e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Baculo_PEP_C PF04513.12 AMK76590.1 - 0.05 13.6 0.2 0.61 10.1 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 AMK76591.1 - 7.4e-27 93.8 7.8 1.2e-14 54.7 0.5 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AMK76591.1 - 5.1e-17 62.0 0.3 2e-07 31.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 AMK76591.1 - 7.6e-16 57.8 4.1 3.3e-07 30.4 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 AMK76591.1 - 4.7e-11 41.9 0.7 0.00029 21.1 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 AMK76591.1 - 3.4e-10 39.9 1.7 1.2e-07 31.9 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) GRDA PF04723.14 AMK76591.1 - 0.002 17.9 0.2 0.0031 17.3 0.2 1.3 1 0 0 1 1 1 1 Glycine reductase complex selenoprotein A Ribosomal_60s PF00428.19 AMK76591.1 - 2.1 9.0 12.3 0.79 10.4 8.5 2.2 2 1 1 3 3 3 0 60s Acidic ribosomal protein DUF525 PF04379.14 AMK76592.1 - 7.4e-36 122.3 0.1 9e-36 122.0 0.1 1.1 1 0 0 1 1 1 1 ApaG domain DUF4354 PF14263.6 AMK76592.1 - 0.0044 16.8 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4354) Metallophos PF00149.28 AMK76593.1 - 2.2e-16 61.0 0.1 3.3e-16 60.4 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK76593.1 - 2e-05 24.8 0.0 3.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metal_resist PF13801.6 AMK76594.1 - 1.2e-08 35.2 3.8 1.5e-06 28.4 0.0 2.0 1 1 1 2 2 2 2 Heavy-metal resistance LTXXQ PF07813.12 AMK76594.1 - 0.0004 21.1 11.7 0.013 16.2 11.7 2.2 1 1 0 1 1 1 1 LTXXQ motif family protein CHASE3 PF05227.13 AMK76594.1 - 0.0069 16.3 4.5 0.013 15.4 4.5 1.4 1 1 0 1 1 1 1 CHASE3 domain Mitofilin PF09731.9 AMK76594.1 - 0.017 14.0 4.5 0.019 13.8 4.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3437 PF11919.8 AMK76594.1 - 0.023 14.6 0.2 0.029 14.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Cor1 PF04803.12 AMK76594.1 - 0.038 14.2 8.2 0.05 13.8 8.2 1.1 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region GTSE1_N PF15259.6 AMK76594.1 - 0.041 14.1 1.7 0.051 13.8 1.7 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 DUF2680 PF10925.8 AMK76594.1 - 0.43 10.6 5.9 7 6.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF2756 PF10956.8 AMK76594.1 - 7.3 7.2 9.2 9.2 6.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2756) AdoMet_dc PF02675.15 AMK76595.1 - 5.4e-33 113.4 0.0 1.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase DUF1323 PF07037.11 AMK76595.1 - 0.084 13.3 0.5 0.084 13.3 0.5 1.8 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) OsmC PF02566.19 AMK76596.1 - 8.7e-16 58.2 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Helicase_PWI PF18149.1 AMK76596.1 - 0.018 15.2 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal helicase PWI domain Glyoxalase_6 PF18029.1 AMK76596.1 - 0.13 13.1 0.0 0.18 12.6 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain cNMP_binding PF00027.29 AMK76597.1 - 3.4e-15 55.9 0.0 5.3e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AMK76597.1 - 2.7e-13 49.7 0.0 5.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AMK76597.1 - 6e-11 41.8 0.3 1.5e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family MarR PF01047.22 AMK76597.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AMK76597.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 AMK76597.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 AMK76597.1 - 0.029 13.9 0.1 0.065 12.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AMK76597.1 - 0.047 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_36 PF13730.6 AMK76597.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SgrR_N PF12793.7 AMK76597.1 - 0.12 12.6 0.1 0.93 9.7 0.0 2.2 2 1 0 2 2 2 0 Sugar transport-related sRNA regulator N-term Rrf2 PF02082.20 AMK76597.1 - 0.14 12.6 0.0 0.68 10.3 0.0 2.2 2 1 0 2 2 2 0 Transcriptional regulator ACR_tran PF00873.19 AMK76598.1 - 1e-224 748.5 15.5 1.2e-224 748.2 15.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AMK76598.1 - 2.3e-06 27.1 22.6 8.3e-06 25.3 9.5 2.3 2 0 0 2 2 2 2 Protein export membrane protein MMPL PF03176.15 AMK76598.1 - 7.8e-05 21.8 48.0 0.0065 15.4 20.8 3.2 2 2 1 3 3 3 2 MMPL family DuoxA PF10204.9 AMK76598.1 - 0.021 13.9 0.4 0.021 13.9 0.4 2.6 2 0 0 2 2 2 0 Dual oxidase maturation factor Prominin PF05478.11 AMK76598.1 - 0.17 9.8 0.4 0.82 7.5 0.1 1.9 2 0 0 2 2 2 0 Prominin DUF2975 PF11188.8 AMK76598.1 - 3.8 7.4 19.6 0.34 10.8 10.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) HlyD_D23 PF16576.5 AMK76599.1 - 5.6e-12 45.3 3.5 9.1e-12 44.7 3.5 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76599.1 - 9.4e-12 45.6 1.9 8.7e-09 36.0 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK76599.1 - 4.2e-09 36.1 5.4 6.7e-09 35.4 3.6 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76599.1 - 0.0044 16.8 0.0 0.085 12.7 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AMK76599.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 AMK76599.1 - 0.051 13.5 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain TetR_C_7 PF14246.6 AMK76600.1 - 3e-28 98.3 2.7 4.6e-28 97.6 2.7 1.3 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AMK76600.1 - 5.3e-18 64.6 1.8 8.2e-18 63.9 0.5 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AMK76600.1 - 0.00061 20.1 0.2 0.0016 18.7 0.2 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 AMK76600.1 - 0.00099 19.3 0.1 0.0019 18.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 AMK76600.1 - 0.0077 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_22 PF13309.6 AMK76600.1 - 0.11 12.6 0.2 0.69 10.0 0.1 2.4 3 0 0 3 3 3 0 HTH domain HAD_2 PF13419.6 AMK76600.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DLH PF01738.18 AMK76601.1 - 9.8e-51 172.4 0.3 1.1e-50 172.2 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AMK76601.1 - 1e-10 41.5 0.5 8.6e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 AMK76601.1 - 2.6e-09 37.3 1.8 4.2e-05 23.6 0.1 3.0 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AMK76601.1 - 5.3e-08 32.4 0.4 0.003 16.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AMK76601.1 - 1.3e-05 25.0 0.0 7.4e-05 22.5 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 AMK76601.1 - 0.0022 17.8 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 AMK76601.1 - 0.0029 17.3 1.0 1.1 8.7 0.6 2.6 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 AMK76601.1 - 0.0034 16.2 0.0 0.0059 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) PAF-AH_p_II PF03403.13 AMK76601.1 - 0.0072 14.9 0.0 0.012 14.1 0.0 1.4 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 AMK76601.1 - 0.022 13.4 0.6 0.093 11.4 0.6 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Acetyltransf_17 PF17668.1 AMK76601.1 - 0.066 14.0 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 AMK76602.1 - 5.6e-44 150.5 39.2 1.1e-26 93.6 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AMK76602.1 - 3.9e-17 62.2 21.9 8.5e-09 34.8 4.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AMK76602.1 - 7.1e-09 35.0 16.3 1.1e-05 24.5 9.5 2.5 1 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 AMK76602.1 - 0.0006 18.3 3.6 0.0006 18.3 3.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 AMK76602.1 - 0.00092 18.1 18.0 0.0026 16.6 3.3 2.7 1 1 1 2 2 2 2 LacY proton/sugar symporter DUF697 PF05128.12 AMK76602.1 - 0.72 9.6 4.9 2.9 7.6 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF697) DUF3953 PF13129.6 AMK76602.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) PAS_9 PF13426.7 AMK76603.1 - 1.2e-31 109.1 0.0 1.2e-10 41.6 0.0 4.3 4 0 0 4 4 4 4 PAS domain PAS_4 PF08448.10 AMK76603.1 - 2.2e-28 98.7 0.0 5.8e-11 42.6 0.0 4.2 4 0 0 4 4 4 4 PAS fold PAS PF00989.25 AMK76603.1 - 2.7e-26 91.8 0.0 2e-05 24.6 0.0 4.5 4 1 0 4 4 4 4 PAS fold PAS_8 PF13188.7 AMK76603.1 - 8.9e-20 70.3 0.0 0.00054 19.9 0.0 4.4 4 0 0 4 4 4 4 PAS domain PAS_3 PF08447.12 AMK76603.1 - 1.6e-14 53.9 0.0 0.00051 20.3 0.0 4.8 4 1 0 4 4 4 3 PAS fold PAS_7 PF12860.7 AMK76603.1 - 0.00025 21.2 0.0 4.1 7.6 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_6 PF08348.11 AMK76603.1 - 0.083 12.8 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 YheO-like PAS domain Ribosomal_S24e PF01282.19 AMK76603.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S24e HKR_ArcB_TM PF18415.1 AMK76603.1 - 0.19 12.5 3.5 0.37 11.6 3.5 1.5 1 0 0 1 1 1 0 Histidine kinase receptor ArcB trans-membrane domain DDE_Tnp_1 PF01609.21 AMK76604.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK76604.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK76604.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK76604.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK76604.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK76604.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK76604.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK76604.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK76604.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK76604.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK76604.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK76604.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK76604.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain DDE_Tnp_1_2 PF13586.6 AMK76605.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76605.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76605.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK76605.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 AMK76606.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_5 PF01022.20 AMK76606.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AMK76606.1 - 0.00036 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AMK76606.1 - 0.0018 18.0 1.3 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AMK76606.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.12 AMK76606.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AMK76606.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK76606.1 - 0.037 13.8 0.1 0.89 9.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 AMK76606.1 - 0.038 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK76606.1 - 0.044 13.8 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 AMK76606.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 AMK76606.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 AMK76606.1 - 0.12 12.5 0.0 0.81 9.9 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AMK76606.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain IstB_IS21 PF01695.17 AMK76607.1 - 4.8e-56 189.3 0.0 6.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK76607.1 - 2e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK76607.1 - 4.1e-06 26.4 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AMK76607.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AMK76607.1 - 0.0068 15.3 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK76607.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AMK76607.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AMK76607.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AMK76607.1 - 0.031 14.5 0.5 0.28 11.5 0.3 2.1 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 AMK76607.1 - 0.031 13.3 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 AMK76607.1 - 0.044 13.5 0.2 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 AMK76607.1 - 0.05 13.5 1.6 0.87 9.5 0.0 2.5 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 AMK76607.1 - 0.054 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AMK76607.1 - 0.096 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AMK76607.1 - 0.11 12.9 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 AMK76607.1 - 0.12 12.1 0.3 0.33 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK76607.1 - 0.13 12.6 2.0 0.25 11.6 1.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK76607.1 - 0.17 11.9 0.3 0.47 10.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AMK76607.1 - 0.32 11.0 1.2 0.73 9.8 0.6 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LysR_substrate PF03466.20 AMK76609.1 - 6.8e-40 136.7 0.0 8.9e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK76609.1 - 1.4e-17 63.4 2.4 6.2e-17 61.3 2.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 AMK76609.1 - 0.059 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain adh_short_C2 PF13561.6 AMK76610.1 - 2.2e-59 200.8 0.4 2.5e-59 200.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AMK76610.1 - 1e-54 185.0 0.5 1.2e-54 184.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK76610.1 - 1.6e-18 67.2 1.0 2.1e-18 66.8 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AMK76610.1 - 2.3e-06 27.2 1.9 1.5e-05 24.6 1.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AMK76610.1 - 0.00014 21.0 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AMK76610.1 - 0.00072 18.8 0.2 0.0015 17.7 0.2 1.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AMK76610.1 - 0.0012 18.3 0.4 0.0025 17.3 0.3 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AMK76610.1 - 0.0021 18.0 0.5 0.0025 17.7 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Peripla_BP_6 PF13458.6 AMK76610.1 - 0.033 13.8 0.6 0.044 13.4 0.6 1.2 1 0 0 1 1 1 0 Periplasmic binding protein NmrA PF05368.13 AMK76610.1 - 0.16 11.5 0.9 0.25 10.9 0.8 1.4 1 1 0 1 1 1 0 NmrA-like family DUF4096 PF13340.6 AMK76611.1 - 3.6e-24 84.8 4.8 7.4e-24 83.8 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK76612.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76612.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76612.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK76612.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Oxidored_FMN PF00724.20 AMK76613.1 - 2.6e-08 33.5 0.0 2.7e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CbtA PF09490.10 AMK76614.1 - 7e-55 186.4 13.4 8e-55 186.3 13.4 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) VKOR PF07884.14 AMK76614.1 - 0.29 11.3 4.7 0.072 13.3 1.0 2.0 2 1 0 2 2 2 0 Vitamin K epoxide reductase family GATase_3 PF07685.14 AMK76615.1 - 5.1e-21 75.2 0.0 6.2e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AMK76615.1 - 0.049 13.7 0.5 0.077 13.0 0.5 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TP_methylase PF00590.20 AMK76616.1 - 1.1e-44 152.9 0.4 1.3e-44 152.7 0.4 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiX PF01903.17 AMK76617.1 - 2.1e-42 143.8 0.1 8.9e-23 80.7 0.1 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 AMK76617.1 - 0.00044 19.7 0.0 2 7.7 0.0 3.0 1 1 0 2 2 2 2 Cobalt chelatase (CbiK) Cas_csx3 PF09620.10 AMK76617.1 - 0.04 13.8 0.0 12 5.8 0.0 2.6 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_csx3) CbiC PF02570.15 AMK76618.1 - 5.8e-74 248.0 0.3 6.7e-74 247.8 0.3 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiD PF01888.17 AMK76619.1 - 2.2e-89 299.1 2.6 2.7e-89 298.8 2.6 1.1 1 0 0 1 1 1 1 CbiD TP_methylase PF00590.20 AMK76620.1 - 1.6e-20 74.0 0.3 2.6e-20 73.3 0.3 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Methyltransf_31 PF13847.6 AMK76620.1 - 1.7e-05 24.6 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76620.1 - 9.6e-05 23.0 0.0 0.00036 21.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AMK76620.1 - 0.0041 16.8 0.0 0.0098 15.5 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.14 AMK76620.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 AMK76620.1 - 0.0057 16.1 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.15 AMK76620.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.19 AMK76620.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) V4R PF02830.18 AMK76620.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 V4R domain TP_methylase PF00590.20 AMK76621.1 - 1.3e-43 149.4 0.1 1.7e-43 149.1 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiG_N PF11760.8 AMK76622.1 - 9.6e-34 115.2 1.3 1.9e-33 114.3 0.2 2.0 2 0 0 2 2 2 1 Cobalamin synthesis G N-terminal CbiG_mid PF11761.8 AMK76622.1 - 2.3e-13 50.0 0.4 6.3e-13 48.7 0.3 1.8 2 0 0 2 2 2 1 Cobalamin biosynthesis central region CbiG_C PF01890.16 AMK76623.1 - 1.6e-36 125.4 0.0 1.8e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus TP_methylase PF00590.20 AMK76624.1 - 2.5e-34 119.1 0.1 4.5e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ChuX_HutX PF06228.13 AMK76624.1 - 6.2e-11 42.2 0.1 1.1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX HemS PF05171.12 AMK76624.1 - 7.1e-09 35.7 0.1 3.9e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 Haemin-degrading HemS.ChuX domain 2Fe-2S_thioredx PF01257.19 AMK76625.1 - 6.3e-06 26.1 0.1 7.6e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Suc_Fer-like PF06999.12 AMK76625.1 - 0.013 15.3 0.0 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Sucrase/ferredoxin-like DDE_Tnp_1_2 PF13586.6 AMK76626.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76626.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76626.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK76626.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4096 PF13340.6 AMK76627.1 - 6.7e-24 83.9 4.8 1.4e-23 82.9 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Pyr_redox_2 PF07992.14 AMK76628.1 - 2e-50 171.7 0.2 2.8e-50 171.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 AMK76628.1 - 2.8e-20 72.0 0.0 8.1e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 AMK76628.1 - 9.9e-18 64.5 1.0 8.2e-17 61.5 0.2 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK76628.1 - 2.7e-09 36.7 0.0 4.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AMK76628.1 - 1.8e-05 25.1 0.0 0.0021 18.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 AMK76628.1 - 0.00031 20.1 0.4 0.0042 16.4 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 AMK76628.1 - 0.00047 19.0 1.3 3.1 6.4 0.1 3.9 3 2 0 5 5 5 2 HI0933-like protein NAD_binding_9 PF13454.6 AMK76628.1 - 0.00073 19.6 0.7 0.57 10.2 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AMK76628.1 - 0.0026 17.9 0.1 0.47 10.7 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AMK76628.1 - 0.0028 16.9 1.4 0.3 10.3 0.9 2.3 1 1 1 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 AMK76628.1 - 0.005 16.7 0.3 0.0093 15.9 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 AMK76628.1 - 0.009 15.6 0.1 0.11 12.1 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.18 AMK76628.1 - 0.023 15.0 0.2 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 AMK76628.1 - 0.025 13.7 1.4 0.27 10.3 0.2 3.0 3 1 1 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AMK76628.1 - 0.055 12.6 3.8 0.63 9.0 0.3 3.2 2 1 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 AMK76628.1 - 0.059 12.2 0.5 0.69 8.7 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase K_oxygenase PF13434.6 AMK76628.1 - 0.085 12.0 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 AMK76628.1 - 0.14 12.2 0.9 8.5 6.4 0.2 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_11 PF13247.6 AMK76629.1 - 1.8e-22 79.4 8.4 1.8e-22 79.4 8.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain DmsC PF04976.12 AMK76629.1 - 8.5e-19 68.1 13.4 1.2e-18 67.6 13.4 1.1 1 0 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) Fer4_7 PF12838.7 AMK76629.1 - 2.9e-09 37.4 21.7 0.00051 20.6 9.0 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK76629.1 - 1.8e-08 34.4 22.2 0.00053 20.1 7.3 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK76629.1 - 8.2e-07 28.8 30.4 6.6e-05 22.8 1.9 4.4 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4 PF00037.27 AMK76629.1 - 1.3e-06 27.9 11.7 4.6e-06 26.2 2.1 4.6 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_10 PF13237.6 AMK76629.1 - 5.8e-06 26.3 25.7 0.00011 22.2 7.0 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK76629.1 - 0.0004 20.7 33.5 0.026 15.0 3.1 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_6 PF12837.7 AMK76629.1 - 0.00092 19.2 10.9 0.003 17.5 1.9 4.4 4 1 0 4 4 3 3 4Fe-4S binding domain Fer4_3 PF12798.7 AMK76629.1 - 0.013 16.4 37.3 0.14 13.2 3.7 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_17 PF13534.6 AMK76629.1 - 0.1 13.1 0.4 0.1 13.1 0.4 3.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain DUF4337 PF14235.6 AMK76629.1 - 0.24 11.5 0.8 0.52 10.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fer4_21 PF14697.6 AMK76629.1 - 0.26 11.4 23.4 1 9.5 3.6 3.0 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK76629.1 - 0.34 11.9 24.4 0.57 11.1 2.6 4.6 3 1 1 5 5 5 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AMK76629.1 - 0.35 11.7 11.5 3.2 8.6 3.1 2.9 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK76629.1 - 7.8 7.0 25.7 2.2 8.8 10.1 3.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Molybdopterin PF00384.22 AMK76630.1 - 6.3e-81 272.5 0.0 7.7e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AMK76630.1 - 1.7e-26 92.4 0.0 3.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AMK76630.1 - 3.3e-10 39.8 1.1 9.6e-10 38.3 0.9 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain HTH_29 PF13551.6 AMK76630.1 - 0.081 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix PhzC-PhzF PF02567.16 AMK76631.1 - 2.2e-48 165.2 0.0 2.5e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Rieske_2 PF13806.6 AMK76632.1 - 4.1e-39 132.7 0.1 4.6e-39 132.6 0.1 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF4656 PF15551.6 AMK76632.1 - 0.13 11.7 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) Pyr_redox_2 PF07992.14 AMK76633.1 - 1.8e-50 171.8 0.1 3e-50 171.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 AMK76633.1 - 1.7e-18 66.7 0.0 3.1e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 AMK76633.1 - 1.1e-16 61.1 0.6 1.7e-13 50.9 0.1 3.7 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AMK76633.1 - 2e-14 53.7 7.9 3.5e-10 40.1 4.8 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 AMK76633.1 - 5.9e-11 42.1 0.0 2.2e-10 40.2 0.0 2.1 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 AMK76633.1 - 6.8e-11 41.9 0.1 2.5e-10 40.1 0.1 2.1 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 AMK76633.1 - 5.4e-05 22.6 0.0 0.00012 21.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK76633.1 - 0.0046 16.6 0.2 0.13 11.8 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK76633.1 - 0.0064 15.6 2.2 1 8.4 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 AMK76633.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AMK76633.1 - 0.02 15.1 0.1 0.061 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 AMK76633.1 - 0.025 13.7 0.1 0.57 9.2 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AMK76633.1 - 0.14 11.4 1.3 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 AMK76633.1 - 0.19 10.9 0.2 0.31 10.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_dim PF02852.22 AMK76633.1 - 0.37 11.1 1.4 1.2 9.4 0.0 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MFS_1 PF07690.16 AMK76634.1 - 1e-40 139.8 76.6 3.7e-33 114.9 49.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AMK76634.1 - 5.4e-08 32.1 36.1 9.6e-07 28.0 6.7 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter Pkinase PF00069.25 AMK76636.1 - 6.3e-37 127.4 0.0 1e-36 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AMK76636.1 - 6.2e-25 87.9 0.0 9.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 AMK76636.1 - 1.3e-10 41.3 0.1 2.2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AMK76636.1 - 6e-09 35.9 0.2 7.8e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C Kdo PF06293.14 AMK76636.1 - 3.8e-06 26.4 0.2 8.1e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AMK76636.1 - 8.6e-06 25.8 0.1 0.038 13.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family SpoIIE PF07228.12 AMK76636.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Seadorna_VP7 PF07387.11 AMK76636.1 - 0.0036 16.4 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 AMK76636.1 - 0.02 14.5 0.2 0.044 13.4 0.2 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF772 PF05598.11 AMK76637.1 - 2.4e-22 78.7 0.7 3e-21 75.2 0.3 2.9 2 1 1 3 3 3 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AMK76637.1 - 3.1e-14 53.1 0.5 8.8e-14 51.7 0.5 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK76637.1 - 5.2e-10 39.6 0.1 1.2e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AMK76637.1 - 2.9e-05 24.3 0.0 6.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76637.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Methyltransf_14 PF08484.11 AMK76638.1 - 0.054 13.3 0.7 0.19 11.5 0.1 1.8 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain EAL PF00563.20 AMK76639.1 - 1.3e-71 240.9 0.1 8.2e-71 238.3 0.0 2.2 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK76639.1 - 1.7e-52 177.4 1.3 3.4e-52 176.4 1.3 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK76639.1 - 5.6e-24 84.5 0.0 1.3e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 AMK76639.1 - 8.6e-22 77.4 0.0 4e-12 46.3 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK76639.1 - 1.6e-19 70.0 0.2 2.1e-08 34.2 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AMK76639.1 - 3.8e-17 62.5 0.0 3.3e-10 40.2 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AMK76639.1 - 4.2e-11 42.6 0.1 2.8e-06 27.2 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 AMK76639.1 - 6e-11 42.5 0.0 1.5e-08 34.8 0.0 2.8 3 0 0 3 3 3 1 PAS fold HisKA_2 PF07568.12 AMK76640.1 - 9.8e-27 92.9 5.5 2.1e-26 91.8 0.2 2.9 3 0 0 3 3 3 1 Histidine kinase PAS PF00989.25 AMK76640.1 - 3.3e-23 81.8 0.0 8e-10 38.7 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 AMK76640.1 - 6.8e-23 80.9 0.0 7.4e-10 39.0 0.0 4.0 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.7 AMK76640.1 - 1.9e-18 66.0 0.1 7.5e-08 32.2 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AMK76640.1 - 2.6e-11 43.8 0.1 0.0003 21.0 0.0 2.9 2 1 0 2 2 2 2 PAS fold GAF PF01590.26 AMK76640.1 - 2.6e-08 34.6 0.0 1.1e-07 32.5 0.0 2.1 2 0 0 2 2 2 1 GAF domain HATPase_c PF02518.26 AMK76640.1 - 1.5e-06 28.7 0.0 4.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 AMK76640.1 - 1.7e-05 25.5 0.9 4.8e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 HWE histidine kinase GAF_3 PF13492.6 AMK76640.1 - 0.0001 22.7 0.0 0.00036 20.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 AMK76640.1 - 0.00017 21.9 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 AMK76640.1 - 0.00094 19.1 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Polysacc_deac_2 PF04748.13 AMK76640.1 - 0.011 14.9 0.6 2.9 7.0 0.1 2.7 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase PAS_7 PF12860.7 AMK76640.1 - 0.062 13.5 0.3 24 5.1 0.0 3.2 3 1 0 3 3 3 0 PAS fold DUF3107 PF11305.8 AMK76640.1 - 3.4 8.0 6.9 13 6.1 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3107) EAL PF00563.20 AMK76642.1 - 1.1e-73 247.7 0.0 1.8e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK76642.1 - 4.5e-50 169.5 1.9 2e-49 167.4 0.1 2.3 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK76642.1 - 6.9e-20 71.3 0.2 2.4e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 PAS domain Response_reg PF00072.24 AMK76642.1 - 7.8e-19 67.9 0.0 2.5e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AMK76642.1 - 2.3e-12 46.9 0.0 8.1e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AMK76642.1 - 3e-09 37.1 0.0 7.3e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK76642.1 - 1.8e-06 28.1 0.0 8.8e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AMK76642.1 - 3.7e-05 23.6 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain Rootletin PF15035.6 AMK76642.1 - 0.025 14.6 3.8 0.047 13.7 3.8 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2802 PF10975.8 AMK76642.1 - 0.081 13.1 2.1 0.26 11.4 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) MRPL52 PF18699.1 AMK76642.1 - 2.6 8.3 5.7 5.5 7.2 5.7 1.4 1 0 0 1 1 1 0 Mitoribosomal protein mL52 HATPase_c PF02518.26 AMK76643.1 - 5.8e-23 81.5 0.1 1.5e-22 80.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AMK76643.1 - 3.5e-14 52.9 0.0 3.3e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 AMK76643.1 - 3.1e-11 43.1 5.7 1.6e-09 37.6 0.0 3.8 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 AMK76643.1 - 3.3e-08 33.9 0.0 7.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AMK76643.1 - 5.7e-07 30.2 0.0 3.1e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 AMK76643.1 - 1.5e-06 28.6 0.0 3.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.7 AMK76643.1 - 6.4e-05 23.2 0.1 0.00037 20.7 0.0 2.4 2 0 0 2 2 1 1 PAS domain PAS_4 PF08448.10 AMK76643.1 - 0.0001 22.5 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 AMK76643.1 - 0.00038 20.3 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 GHKL domain Mce4_CUP1 PF11887.8 AMK76643.1 - 0.0027 17.2 0.8 0.081 12.4 0.1 2.2 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative Talin_middle PF09141.10 AMK76643.1 - 0.03 14.4 2.4 0.78 9.8 0.1 2.9 2 1 1 3 3 3 0 Talin, middle domain HATPase_c_2 PF13581.6 AMK76643.1 - 0.033 14.1 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Jnk-SapK_ap_N PF09744.9 AMK76643.1 - 0.045 14.0 2.3 3.4 7.9 0.5 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 APG17 PF04108.12 AMK76643.1 - 0.054 12.6 5.6 0.13 11.4 5.6 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 HATPase_c_3 PF13589.6 AMK76643.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MscS_porin PF12795.7 AMK76643.1 - 0.42 10.1 12.8 0.25 10.8 1.3 2.6 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 AMK76643.1 - 1.9 8.5 9.8 1 9.3 0.7 2.7 3 0 0 3 3 3 0 Laminin Domain II UPF0449 PF15136.6 AMK76643.1 - 5.6 7.5 6.2 2.7 8.5 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HDOD PF08668.12 AMK76644.1 - 6.1e-56 189.0 0.0 8.6e-56 188.5 0.0 1.2 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK76644.1 - 3.1e-10 40.3 0.5 5.9e-10 39.4 0.5 1.5 1 1 0 1 1 1 1 HD domain tRNA-synt_2_TM PF16995.5 AMK76644.1 - 0.022 14.5 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Response_reg PF00072.24 AMK76645.1 - 6.7e-22 77.8 0.0 1.7e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 AMK76645.1 - 0.00066 19.7 0.5 0.0076 16.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold PRKG1_interact PF15898.5 AMK76645.1 - 0.0037 18.2 1.4 0.0077 17.1 1.4 1.5 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain DUF3865 PF12981.7 AMK76645.1 - 0.004 17.1 0.2 0.025 14.5 0.0 2.0 1 1 0 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3865) GAS PF13851.6 AMK76645.1 - 0.023 14.1 5.1 0.036 13.4 5.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MobL PF18555.1 AMK76645.1 - 0.035 13.3 0.6 0.051 12.8 0.6 1.2 1 0 0 1 1 1 0 MobL relaxases PAS_10 PF13596.6 AMK76645.1 - 0.11 13.1 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 PAS domain DDE_Tnp_1 PF01609.21 AMK76646.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK76646.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK76646.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK76646.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK76646.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK76646.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK76646.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK76646.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK76646.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK76646.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK76646.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK76646.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK76646.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain GGDEF PF00990.21 AMK76647.1 - 1.9e-52 177.3 0.1 2.5e-52 176.9 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK76647.1 - 1.4e-07 31.7 0.0 4.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AMK76647.1 - 0.004 17.4 0.1 0.011 16.0 0.1 1.7 1 0 0 1 1 1 1 PAS fold VanY PF02557.17 AMK76647.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Peptidase_M23 PF01551.22 AMK76648.1 - 3.2e-20 72.1 0.2 5.8e-20 71.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M23 DUF4124 PF13511.6 AMK76648.1 - 0.0001 22.6 0.2 0.0002 21.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) SmpA_OmlA PF04355.13 AMK76649.1 - 3.2e-06 26.8 0.1 3.8e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 SmpA / OmlA family UPF0061 PF02696.14 AMK76650.1 - 1.7e-141 472.2 0.1 2.1e-141 471.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Cadherin_5 PF17892.1 AMK76651.1 - 0.0062 16.5 7.8 0.37 10.8 0.1 4.2 4 0 0 4 4 4 3 Cadherin-like domain PDH_E1_M PF17831.1 AMK76653.1 - 1.2e-110 368.5 0.0 1.9e-110 367.8 0.0 1.3 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 AMK76653.1 - 1.9e-13 50.1 0.0 9.5e-09 34.6 0.0 2.4 2 1 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AMK76653.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain 2-oxoacid_dh PF00198.23 AMK76654.1 - 2.7e-77 259.3 0.0 3.5e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AMK76654.1 - 2.3e-19 69.0 3.6 4.2e-19 68.1 3.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AMK76654.1 - 1.3e-13 51.1 0.1 2.7e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AMK76654.1 - 6.1e-06 26.0 0.4 0.00069 19.4 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 AMK76654.1 - 0.078 12.9 0.3 1.7 8.6 0.2 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 AMK76654.1 - 0.082 12.6 0.2 1.6 8.4 0.0 2.4 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.19 AMK76654.1 - 0.089 12.7 1.7 0.47 10.4 0.3 2.2 1 1 1 2 2 2 0 Glycine cleavage H-protein Ciart PF15673.5 AMK76654.1 - 0.2 11.0 1.5 0.34 10.3 1.5 1.3 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor Pyr_redox_2 PF07992.14 AMK76655.1 - 2.1e-63 214.3 1.4 2.9e-63 213.8 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AMK76655.1 - 3.8e-31 107.6 0.0 1.2e-30 106.0 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AMK76655.1 - 4.2e-21 75.3 1.6 1.1e-16 61.1 0.1 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AMK76655.1 - 5.9e-11 42.4 0.5 5.9e-11 42.4 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AMK76655.1 - 1e-09 38.1 1.2 3.9e-07 29.6 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK76655.1 - 5.3e-07 29.1 6.7 2.9e-05 23.4 0.4 3.3 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 AMK76655.1 - 1e-06 28.2 3.1 0.0061 15.9 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AMK76655.1 - 3.7e-06 26.3 6.9 8.2e-06 25.1 2.4 3.0 3 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AMK76655.1 - 5.5e-05 23.3 10.4 0.00056 20.1 0.4 3.2 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AMK76655.1 - 0.00043 19.1 7.9 0.0036 16.1 0.2 3.5 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 AMK76655.1 - 0.0011 18.3 2.6 0.031 13.5 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 AMK76655.1 - 0.0057 16.0 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Spermine_synth PF01564.17 AMK76655.1 - 0.016 14.6 0.3 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Thi4 PF01946.17 AMK76655.1 - 0.024 13.9 0.8 0.14 11.4 0.2 2.2 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 AMK76655.1 - 0.026 14.1 12.8 0.69 9.4 0.6 4.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AMK76655.1 - 0.027 14.9 1.5 4 7.9 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 AMK76655.1 - 0.047 12.5 0.6 0.39 9.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 AMK76655.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApoLp-III PF07464.11 AMK76656.1 - 0.031 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Lant_dehydr_C PF14028.6 AMK76656.1 - 0.044 13.3 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term AAA_24 PF13479.6 AMK76656.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Protoglobin PF11563.8 AMK76657.1 - 0.0032 17.4 0.1 0.0054 16.7 0.1 1.4 1 0 0 1 1 1 1 Protoglobin FANCI_S1 PF14675.6 AMK76657.1 - 0.12 11.9 0.0 0.78 9.3 0.0 1.9 2 0 0 2 2 2 0 FANCI solenoid 1 Iron_traffic PF04362.14 AMK76658.1 - 1.2e-37 127.4 0.0 1.3e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking NUDIX_4 PF14815.6 AMK76659.1 - 1.3e-22 79.8 0.0 2.6e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 AMK76659.1 - 3.5e-22 78.9 0.0 5.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AMK76659.1 - 4.6e-09 35.7 0.1 9.9e-09 34.6 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AMK76659.1 - 0.0003 21.0 5.1 0.00062 20.0 5.1 1.6 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Whib PF02467.16 AMK76659.1 - 0.012 16.2 1.0 1.2 9.8 0.6 2.4 2 0 0 2 2 2 0 Transcription factor WhiB HHH_5 PF14520.6 AMK76659.1 - 0.024 15.2 0.1 0.24 12.0 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix domain Cdd1 PF11731.8 AMK76659.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus zinc_ribbon_2 PF13240.6 AMK76660.1 - 6.2e-11 41.7 14.0 1.9e-05 24.2 4.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 AMK76660.1 - 3.6e-10 39.7 16.3 5e-10 39.3 16.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 AMK76660.1 - 5.5e-09 35.1 15.9 0.0001 21.6 3.6 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AMK76660.1 - 5.4e-07 30.3 8.0 0.0043 17.8 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon family UPF0547 PF10571.9 AMK76660.1 - 2.5e-06 27.4 15.1 0.00038 20.5 5.2 2.3 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 PolC_DP2 PF03833.13 AMK76660.1 - 0.00014 19.9 3.6 0.00017 19.6 3.6 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 AMK76660.1 - 0.00094 19.1 9.9 0.004 17.1 10.2 1.8 1 1 1 2 2 2 1 zinc-ribbons Zn-ribbon_8 PF09723.10 AMK76660.1 - 0.0075 16.4 16.3 0.062 13.4 0.3 3.7 1 1 1 2 2 2 1 Zinc ribbon domain PHF5 PF03660.14 AMK76660.1 - 0.014 15.6 4.9 0.022 14.9 4.9 1.3 1 0 0 1 1 1 0 PHF5-like protein Nudix_N_2 PF14803.6 AMK76660.1 - 0.025 14.5 16.0 3.4 7.7 0.1 4.2 3 1 1 4 4 4 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 AMK76660.1 - 0.076 12.9 13.4 0.12 12.3 3.6 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbon_6 PF10005.9 AMK76660.1 - 0.095 13.4 8.8 0.63 10.8 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Cript PF10235.9 AMK76660.1 - 0.13 12.8 12.2 0.89 10.2 12.2 2.0 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT PknG_rubred PF16919.5 AMK76660.1 - 0.14 12.3 7.8 2.5 8.3 0.0 2.3 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Prok-RING_4 PF14447.6 AMK76660.1 - 0.15 11.9 6.5 0.61 10.0 1.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3090 PF11290.8 AMK76660.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) zf-C3HC4_3 PF13920.6 AMK76660.1 - 0.2 11.5 10.0 0.47 10.3 1.4 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 AMK76660.1 - 0.35 10.3 5.6 0.11 11.9 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) zf_Rg PF17915.1 AMK76660.1 - 0.54 9.7 7.6 9.4 5.7 0.1 3.6 3 1 1 4 4 4 0 Reverse gyrase zinc finger HypA PF01155.19 AMK76660.1 - 1.1 9.3 12.9 3.3 7.8 2.6 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 AMK76660.1 - 1.2 9.3 14.7 2.4 8.4 1.3 3.1 1 1 2 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF2321 PF10083.9 AMK76660.1 - 1.7 8.2 9.7 4 7.0 9.7 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Ribosomal_L32p PF01783.23 AMK76660.1 - 2.5 8.4 10.1 1.3 9.4 2.5 2.4 1 1 1 2 2 2 0 Ribosomal L32p protein family TF_Zn_Ribbon PF08271.12 AMK76660.1 - 2.5 7.7 13.2 41 3.8 7.4 3.4 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_S27 PF01599.19 AMK76660.1 - 3.3 8.0 12.2 11 6.2 1.7 2.6 1 1 1 2 2 2 0 Ribosomal protein S27a zf-HIT PF04438.16 AMK76660.1 - 3.5 7.6 11.1 3.4 7.6 5.7 2.6 2 1 1 3 3 3 0 HIT zinc finger DNA_RNApol_7kD PF03604.13 AMK76660.1 - 3.7 7.3 11.1 1.7 8.4 1.7 2.7 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit tRNA-synt_1g PF09334.11 AMK76660.1 - 4.9 5.8 7.5 3.8 6.2 0.6 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (M) DNA_ligase_ZBD PF03119.16 AMK76660.1 - 5.4 7.1 13.5 4.6 7.4 0.3 3.5 3 1 1 4 4 3 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1272 PF06906.11 AMK76660.1 - 9.8 6.4 14.5 1.6e+02 2.5 9.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) Flavin_Reduct PF01613.18 AMK76661.1 - 5.7e-26 91.4 0.0 7.6e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain HH_signal PF01085.18 AMK76661.1 - 0.043 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF359 PF04019.12 AMK76662.1 - 0.028 14.1 0.2 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF359) LprI PF07007.12 AMK76662.1 - 0.14 12.8 4.1 0.55 10.9 1.3 2.0 1 1 1 2 2 2 0 Lysozyme inhibitor LprI CemA PF03040.14 AMK76662.1 - 0.36 10.7 3.4 0.37 10.7 3.4 1.1 1 0 0 1 1 1 0 CemA family PKD PF00801.20 AMK76664.1 - 2.6e-14 52.8 1.8 1.4e-13 50.5 1.8 2.3 1 0 0 1 1 1 1 PKD domain Reprolysin_3 PF13582.6 AMK76664.1 - 0.00011 22.7 0.1 0.00042 20.8 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 AMK76664.1 - 0.0004 20.6 0.0 0.0004 20.6 0.0 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 AMK76664.1 - 0.025 13.6 0.3 0.05 12.6 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 AMK76664.1 - 0.12 11.5 0.3 2.5 7.2 0.1 2.2 2 0 0 2 2 2 0 Met-zincin ABC_tran PF00005.27 AMK76665.1 - 9.2e-48 162.2 2.8 1e-22 81.1 0.0 3.4 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 AMK76665.1 - 6.6e-28 96.6 6.4 6.6e-28 96.6 6.4 3.4 3 1 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 AMK76665.1 - 6.8e-15 55.7 12.4 0.00025 20.9 0.2 4.5 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK76665.1 - 1.1e-09 38.0 1.2 0.0025 17.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 AMK76665.1 - 3.3e-07 30.5 20.9 3.9e-07 30.2 9.3 4.0 3 1 1 4 4 4 1 ABC transporter C-terminal domain RsgA_GTPase PF03193.16 AMK76665.1 - 2e-06 27.8 0.7 0.013 15.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 AMK76665.1 - 2.5e-06 27.1 1.4 0.025 14.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AMK76665.1 - 2.6e-06 27.5 0.0 0.022 14.9 0.0 3.2 2 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 AMK76665.1 - 3.9e-06 27.5 17.5 0.25 11.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 AMK76665.1 - 2.8e-05 24.7 0.0 0.23 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain KAP_NTPase PF07693.14 AMK76665.1 - 0.00064 19.1 0.3 0.11 11.8 0.1 2.4 2 1 0 2 2 2 1 KAP family P-loop domain DUF815 PF05673.13 AMK76665.1 - 0.0025 17.0 0.0 1 8.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 AMK76665.1 - 0.0077 16.6 13.8 0.061 13.7 0.1 3.7 3 1 1 4 4 4 2 AAA ATPase domain ATP-synt_ab PF00006.25 AMK76665.1 - 0.012 15.3 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 AMK76665.1 - 0.021 15.1 3.1 5.6 7.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 AMK76665.1 - 0.024 14.0 0.3 0.21 10.9 0.1 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FliD_N PF02465.18 AMK76665.1 - 0.034 14.9 1.3 0.034 14.9 1.3 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AAA_24 PF13479.6 AMK76665.1 - 0.037 13.8 0.4 10 5.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AMK76665.1 - 0.057 13.7 0.0 19 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 AMK76665.1 - 0.15 12.5 0.0 6.7 7.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 AMK76665.1 - 0.15 12.2 0.1 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 AMK76665.1 - 0.18 12.2 0.7 17 5.9 0.0 3.1 3 0 0 3 3 3 0 RNA helicase MeaB PF03308.16 AMK76665.1 - 0.4 9.6 0.0 0.4 9.6 0.0 3.0 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_E PF05680.12 AMK76665.1 - 1.3 9.4 10.2 0.18 12.2 0.9 2.6 2 0 0 2 2 2 0 ATP synthase E chain Dynamin_N PF00350.23 AMK76665.1 - 5.2 7.1 6.1 6.1 6.9 0.0 3.3 4 0 0 4 4 4 0 Dynamin family PCRF PF03462.18 AMK76665.1 - 6 6.7 10.6 12 5.7 0.9 2.6 2 0 0 2 2 2 0 PCRF domain Usp PF00582.26 AMK76667.1 - 5.8e-32 111.1 0.2 7e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 Universal stress protein family CobU PF02283.16 AMK76668.1 - 4.8e-61 205.2 0.2 5.5e-61 205.0 0.2 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPase PF06745.13 AMK76668.1 - 0.023 14.0 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 KaiC DBI_PRT PF02277.17 AMK76669.1 - 9.6e-125 416.2 16.7 1.1e-124 416.0 16.7 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase NIF3 PF01784.18 AMK76669.1 - 0.056 13.1 0.2 0.086 12.4 0.2 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) TM2 PF05154.16 AMK76670.1 - 3.3e-11 43.3 9.2 5.4e-11 42.6 9.2 1.3 1 0 0 1 1 1 1 TM2 domain CobS PF02654.15 AMK76671.1 - 5.3e-53 180.3 16.9 6e-53 180.1 16.9 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase Nitroreductase PF00881.24 AMK76672.1 - 3.5e-25 89.0 0.0 4.2e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family GATase_3 PF07685.14 AMK76673.1 - 2.4e-53 180.6 0.0 3.8e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AMK76673.1 - 5.2e-22 78.3 0.0 7.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AMK76673.1 - 2e-20 73.5 0.0 3.8e-20 72.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 AMK76673.1 - 0.21 11.5 0.0 0.84 9.5 0.0 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF772 PF05598.11 AMK76674.1 - 1.2e-11 44.4 0.5 2e-11 43.7 0.2 1.5 2 0 0 2 2 2 1 Transposase domain (DUF772) Zip PF02535.22 AMK76676.1 - 4.9e-39 134.5 23.5 3.8e-34 118.4 8.1 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter HRG PF16954.5 AMK76676.1 - 0.016 15.6 0.2 0.016 15.6 0.2 3.0 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene ABA_GPCR PF12430.8 AMK76676.1 - 0.067 13.0 0.1 0.067 13.0 0.1 2.0 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF5056 PF16479.5 AMK76676.1 - 0.34 11.2 4.0 26 5.2 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5056) DUF1129 PF06570.11 AMK76676.1 - 2 7.8 6.1 2 7.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF5489 PF17592.2 AMK76676.1 - 2.3 8.8 9.4 2.2 8.9 0.1 3.6 3 1 0 3 3 3 0 Family of unknown function (DUF5489) Cu-oxidase_4 PF02578.15 AMK76677.1 - 2.8e-76 256.1 0.0 3.2e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase PseudoU_synth_2 PF00849.22 AMK76678.1 - 3.2e-35 121.6 0.1 4.3e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AMK76678.1 - 2.1e-09 36.9 0.1 5.5e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 S4 domain YfiO PF13525.6 AMK76679.1 - 4.8e-66 222.4 11.4 6.4e-66 222.0 11.4 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 AMK76679.1 - 5.7e-45 153.0 6.3 5.7e-45 153.0 6.3 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AMK76679.1 - 1.6e-11 44.1 4.6 0.001 19.5 0.2 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK76679.1 - 2.1e-09 37.8 13.1 1.2e-05 25.8 7.8 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK76679.1 - 0.00016 22.2 1.7 0.17 12.8 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 AMK76679.1 - 0.0037 17.0 1.1 0.0037 17.0 1.1 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 AMK76679.1 - 0.0038 17.2 14.8 0.011 15.8 0.8 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 AMK76679.1 - 0.013 15.8 1.1 0.013 15.8 1.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK76679.1 - 0.022 15.0 0.5 0.022 15.0 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 AMK76679.1 - 0.038 14.1 4.1 0.075 13.1 0.2 3.1 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 AMK76679.1 - 0.061 13.5 0.2 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat nsp9 PF08710.10 AMK76679.1 - 0.086 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 nsp9 replicase TPR_19 PF14559.6 AMK76679.1 - 0.49 10.9 6.2 0.25 11.9 2.2 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AMK76679.1 - 1.3 9.4 7.9 9.7 6.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 AMK76679.1 - 1.6 8.6 14.9 0.16 11.8 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2058 PF09831.9 AMK76681.1 - 1.5e-60 204.3 12.5 1.7e-60 204.2 12.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) Phage_TAC_8 PF10666.9 AMK76681.1 - 0.003 17.8 2.8 0.003 17.8 2.8 1.7 1 1 0 1 1 1 1 Phage tail assembly chaperone protein Gp14 ()A118 Csc2 PF18320.1 AMK76681.1 - 0.034 13.1 4.0 0.041 12.8 2.4 1.8 1 1 1 2 2 2 0 Csc2 Crispr YebF PF13995.6 AMK76681.1 - 0.076 13.0 1.0 0.11 12.5 0.3 1.7 2 0 0 2 2 2 0 YebF-like protein DUF5401 PF17380.2 AMK76681.1 - 0.41 8.7 10.8 0.59 8.1 10.8 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5401) Methyltransf_4 PF02390.17 AMK76682.1 - 3.4e-51 173.1 0.0 4e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 AMK76682.1 - 0.012 16.3 0.0 0.02 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76682.1 - 0.081 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fer2_BFD PF04324.15 AMK76685.1 - 1.3e-10 41.4 0.7 1.6e-10 41.1 0.7 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain DUF4279 PF14106.6 AMK76685.1 - 0.046 13.9 0.0 0.047 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) ThiG PF05690.14 AMK76686.1 - 1.3e-109 365.2 1.3 1.6e-109 365.0 1.3 1.1 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG ThiS PF02597.20 AMK76686.1 - 4.7e-13 49.6 0.3 1.1e-12 48.4 0.3 1.6 1 0 0 1 1 1 1 ThiS family His_biosynth PF00977.21 AMK76686.1 - 0.00012 21.6 0.1 0.00047 19.7 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 AMK76686.1 - 0.0015 17.6 0.2 0.011 14.8 0.1 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Hydrolase PF00702.26 AMK76686.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Dus PF01207.17 AMK76686.1 - 0.071 12.2 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DUF3762 PF12591.8 AMK76686.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) IMPDH PF00478.25 AMK76686.1 - 0.19 10.7 0.8 0.35 9.8 0.8 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF1174 PF06671.11 AMK76686.1 - 0.26 11.1 2.0 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1174) DAHP_synth_1 PF00793.20 AMK76687.1 - 1.1e-101 339.3 0.0 1.5e-101 338.9 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DUF155 PF02582.14 AMK76688.1 - 2.4e-43 148.3 0.0 3.8e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3389 PF11869.8 AMK76688.1 - 0.052 13.7 0.0 0.27 11.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3389) PEP-CTERM PF07589.11 AMK76689.1 - 0.0052 16.8 2.4 0.013 15.6 2.4 1.7 1 0 0 1 1 1 1 PEP-CTERM motif Aminotran_1_2 PF00155.21 AMK76690.1 - 5.1e-26 91.7 0.0 6.6e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CobD_Cbib PF03186.13 AMK76691.1 - 8.3e-93 310.6 0.3 9.5e-93 310.4 0.3 1.0 1 0 0 1 1 1 1 CobD/Cbib protein AmpE PF17113.5 AMK76691.1 - 4.1e-10 39.5 3.5 4.1e-10 39.5 3.5 1.5 2 0 0 2 2 2 1 Regulatory signalling modulator protein AmpE DUF3272 PF11676.8 AMK76692.1 - 0.043 14.1 0.4 0.043 14.1 0.4 3.4 4 1 1 5 5 5 0 Protein of unknown function (DUF3272) TonB_dep_Rec PF00593.24 AMK76693.1 - 2.2e-40 139.9 44.3 3.8e-40 139.2 44.3 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK76693.1 - 9.5e-28 96.9 0.5 9.5e-28 96.9 0.5 2.1 2 1 1 3 3 3 1 TonB-dependent Receptor Plug Domain DUF3146 PF11344.8 AMK76693.1 - 0.53 10.0 2.7 4.7 6.9 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3146) FliW PF02623.15 AMK76694.1 - 6.5e-28 97.1 0.1 7.9e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 FliW protein Asp_decarbox PF02261.16 AMK76695.1 - 5.3e-47 158.5 0.0 6e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Pantoate_ligase PF02569.15 AMK76696.1 - 2.2e-100 335.3 0.0 2.5e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Esterase PF00756.20 AMK76696.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase CTP_transf_like PF01467.26 AMK76696.1 - 0.052 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 AMK76696.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase Pantoate_transf PF02548.15 AMK76697.1 - 1.2e-109 365.6 0.6 1.4e-109 365.4 0.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 AMK76697.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase HPPK PF01288.20 AMK76698.1 - 1.5e-34 118.9 0.0 1.8e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PolyA_pol_arg_C PF12626.7 AMK76699.1 - 5e-38 129.8 0.5 8.2e-38 129.1 0.5 1.3 1 0 0 1 1 1 1 Polymerase A arginine-rich C-terminus PolyA_pol PF01743.20 AMK76699.1 - 2e-37 128.4 0.1 3.6e-37 127.6 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AMK76699.1 - 1.1e-20 73.1 0.0 2.2e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A RDD PF06271.12 AMK76701.1 - 2.2e-24 86.2 5.0 2.6e-24 86.0 5.0 1.0 1 0 0 1 1 1 1 RDD family Lipocalin_8 PF16585.5 AMK76702.1 - 0.016 15.6 0.1 0.11 12.9 0.0 1.9 1 1 0 2 2 2 0 Lipocalin-like domain DUF4148 PF13663.6 AMK76702.1 - 0.15 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) LptF_LptG PF03739.14 AMK76703.1 - 5.9e-63 212.8 6.6 6.7e-63 212.7 6.6 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG LptF_LptG PF03739.14 AMK76704.1 - 3.6e-62 210.3 7.9 4.5e-62 209.9 7.9 1.1 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Colicin_V PF02674.16 AMK76704.1 - 0.0061 16.5 7.2 0.0061 16.5 7.2 2.2 2 0 0 2 2 2 1 Colicin V production protein Peptidase_M17 PF00883.21 AMK76705.1 - 2.7e-119 398.1 0.0 3.4e-119 397.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AMK76705.1 - 1.4e-28 99.3 0.5 3e-28 98.2 0.5 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DNA_pol3_chi PF04364.13 AMK76706.1 - 3.1e-34 118.1 0.0 3.4e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC FMN_bind_2 PF04299.12 AMK76707.1 - 3.8e-56 189.4 0.0 5e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain DUF4181 PF13789.6 AMK76708.1 - 0.0096 16.2 1.0 0.25 11.6 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4181) EXS PF03124.14 AMK76708.1 - 0.046 13.0 2.6 0.11 11.8 2.6 1.5 1 1 0 1 1 1 0 EXS family DUF2207 PF09972.9 AMK76708.1 - 0.38 9.5 3.5 0.27 9.9 2.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 AMK76708.1 - 0.79 9.2 4.0 0.66 9.5 0.2 2.1 2 0 0 2 2 2 0 E1-E2 ATPase YrhC PF14143.6 AMK76708.1 - 2.3 8.3 6.5 0.32 11.1 1.1 2.1 2 1 0 2 2 2 0 YrhC-like protein DUF2721 PF11026.8 AMK76708.1 - 2.6 8.0 10.3 0.3 11.0 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) YcxB PF14317.6 AMK76709.1 - 4.9e-08 32.6 0.0 8.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 YcxB-like protein Glyco_hydro_43 PF04616.14 AMK76709.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 43 DUF1453 PF07301.11 AMK76709.1 - 0.044 13.8 0.1 0.06 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Pyr_redox_2 PF07992.14 AMK76710.1 - 5.5e-61 206.4 0.3 6.5e-61 206.1 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK76710.1 - 2e-17 63.5 1.6 2.9e-11 43.8 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK76710.1 - 4.9e-08 32.9 5.5 0.032 13.8 0.2 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AMK76710.1 - 7.1e-06 25.5 2.9 0.0058 15.9 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AMK76710.1 - 7e-05 22.0 2.1 0.0096 15.0 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 AMK76710.1 - 0.00024 21.1 1.4 0.091 12.8 0.1 2.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 AMK76710.1 - 0.0016 18.6 0.2 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain K_oxygenase PF13434.6 AMK76710.1 - 0.002 17.4 0.1 0.51 9.4 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 AMK76710.1 - 0.0061 16.8 4.0 0.089 13.0 0.6 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 AMK76710.1 - 0.011 15.1 0.4 3.5 6.9 0.0 2.7 3 0 0 3 3 3 0 ThiF family Trp_halogenase PF04820.14 AMK76710.1 - 0.013 14.4 4.2 0.1 11.5 0.3 2.6 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 AMK76710.1 - 0.042 12.6 3.3 0.32 9.6 0.1 3.0 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 AMK76710.1 - 0.048 12.9 3.2 0.98 8.6 0.1 2.6 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 AMK76710.1 - 4.7 6.2 7.3 1.5 7.8 1.1 2.7 3 0 0 3 3 3 0 FAD binding domain ApbA PF02558.16 AMK76710.1 - 5.2 6.7 5.5 23 4.6 0.2 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA DPBB_1 PF03330.18 AMK76711.1 - 2.2e-22 79.1 0.0 3.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase FecR PF04773.13 AMK76713.1 - 5.8e-24 84.5 0.3 1.3e-23 83.4 0.3 1.6 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AMK76713.1 - 1.9e-14 53.2 6.2 1.9e-14 53.2 6.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AMK76713.1 - 3.7e-05 23.7 0.0 6.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) Sigma70_r4_2 PF08281.12 AMK76714.1 - 1.4e-16 59.9 0.2 2.5e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AMK76714.1 - 5.4e-13 48.2 0.1 1e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK76714.1 - 2.6e-09 36.7 1.0 5e-09 35.8 1.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AMK76714.1 - 2.4e-06 27.6 2.1 3.8e-06 26.9 2.1 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_10 PF04967.12 AMK76714.1 - 0.00014 21.6 0.5 0.0004 20.1 0.1 2.0 2 0 0 2 2 2 1 HTH DNA binding domain HTH_24 PF13412.6 AMK76714.1 - 0.00017 21.1 0.0 0.00051 19.5 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AMK76714.1 - 0.0018 18.0 0.1 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain GerE PF00196.19 AMK76714.1 - 0.0022 17.5 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_11 PF08279.12 AMK76714.1 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain HemN_C PF06969.16 AMK76714.1 - 0.012 15.7 0.1 0.044 13.8 0.0 1.9 2 0 0 2 2 2 0 HemN C-terminal domain HTH_20 PF12840.7 AMK76714.1 - 0.015 15.4 0.4 0.038 14.1 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AMK76714.1 - 0.028 14.4 0.1 0.087 12.8 0.1 1.8 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_38 PF13936.6 AMK76714.1 - 0.033 14.0 0.1 0.077 12.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0122 PF04297.14 AMK76714.1 - 0.035 14.3 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.7 AMK76714.1 - 0.053 13.4 0.3 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 MarR family Rrf2 PF02082.20 AMK76714.1 - 0.061 13.7 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator TetR_N PF00440.23 AMK76714.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_5 PF01022.20 AMK76714.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family PepSY_TM PF03929.16 AMK76715.1 - 1.3e-63 215.3 6.8 1.6e-63 215.1 6.8 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AMK76715.1 - 7.4e-06 26.4 0.0 0.22 12.1 0.0 2.9 2 1 0 2 2 2 2 Peptidase propeptide and YPEB domain PMP1_2 PF08114.11 AMK76715.1 - 0.019 14.7 1.0 0.019 14.7 1.0 2.4 2 0 0 2 2 2 0 ATPase proteolipid family DUF4265 PF14085.6 AMK76715.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Cytochrom_B561 PF03188.16 AMK76715.1 - 0.1 12.7 3.9 0.97 9.6 0.1 2.7 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 DUF3040 PF11239.8 AMK76715.1 - 0.21 11.9 2.1 5.3 7.4 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) Ni_hydr_CYTB PF01292.20 AMK76715.1 - 0.89 9.1 9.3 10 5.7 2.3 3.5 3 1 1 4 4 4 0 Prokaryotic cytochrome b561 PepSY_TM_like_2 PF16357.5 AMK76715.1 - 2.5 8.1 5.1 12 5.8 0.3 2.8 3 0 0 3 3 3 0 Putative PepSY_TM-like TonB_dep_Rec PF00593.24 AMK76716.1 - 3.9e-30 106.1 50.5 3.9e-30 106.1 50.5 1.8 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK76716.1 - 1e-17 64.7 5.2 2.1e-17 63.6 1.5 3.2 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AMK76716.1 - 1.7e-13 50.1 0.1 5.8e-13 48.4 0.1 2.0 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AMK76717.1 - 1.4e-20 73.7 0.7 2.5e-20 72.9 0.7 1.5 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AMK76717.1 - 7.9e-11 41.7 6.9 7.9e-11 41.7 6.9 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) Sigma70_r4_2 PF08281.12 AMK76718.1 - 1.1e-12 47.4 0.3 2e-12 46.6 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK76718.1 - 2e-11 43.5 0.1 2e-11 43.5 0.1 2.2 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK76718.1 - 1.9e-08 33.7 0.0 3.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AMK76718.1 - 9.9e-06 25.6 0.1 1.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor BCAS2 PF05700.11 AMK76718.1 - 0.00076 19.2 0.1 0.0014 18.4 0.1 1.4 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) HTH_23 PF13384.6 AMK76718.1 - 0.00079 19.1 0.8 0.0028 17.4 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Phage_antitermQ PF06530.12 AMK76718.1 - 0.0029 17.5 0.2 0.24 11.3 0.1 2.3 2 1 0 2 2 2 1 Phage antitermination protein Q Muted PF14942.6 AMK76718.1 - 0.011 16.0 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein HTH_38 PF13936.6 AMK76718.1 - 0.081 12.7 0.2 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MHB PF16525.5 AMK76718.1 - 0.11 12.7 0.8 2.6 8.4 0.9 2.4 2 0 0 2 2 2 0 Haemophore, haem-binding PSI_PsaJ PF01701.18 AMK76719.1 - 0.11 13.0 2.6 0.15 12.6 1.5 1.8 1 1 1 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ TonB_dep_Rec PF00593.24 AMK76720.1 - 4.5e-26 92.8 32.8 1e-25 91.6 32.8 1.6 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK76720.1 - 3.5e-24 85.4 2.2 1.4e-23 83.5 0.1 2.6 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Toluene_X PF03349.16 AMK76720.1 - 0.00012 20.8 0.2 0.0068 15.0 0.0 2.3 2 0 0 2 2 2 2 Outer membrane protein transport protein (OMPP1/FadL/TodX) TonB_dep_Rec PF00593.24 AMK76721.1 - 1.9e-61 209.4 23.1 1.9e-61 209.4 23.1 2.1 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK76721.1 - 1.7e-13 51.1 0.1 4.5e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AMK76721.1 - 6.3e-08 32.3 0.0 2.1e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain FecR PF04773.13 AMK76722.1 - 7e-24 84.3 0.7 1.5e-23 83.2 0.7 1.6 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 AMK76722.1 - 5.9e-14 51.7 12.5 5.9e-14 51.7 12.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4880) DUF4974 PF16344.5 AMK76722.1 - 1.9e-10 40.6 0.0 3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) Sigma70_r4_2 PF08281.12 AMK76723.1 - 1.1e-12 47.4 0.1 1.9e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK76723.1 - 3.7e-08 33.0 0.2 1.1e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 AMK76723.1 - 1.5e-07 31.5 0.1 1.8e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 AMK76723.1 - 1.1e-06 28.0 0.0 3.4e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 AMK76723.1 - 0.0052 16.5 0.4 0.012 15.4 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 AMK76723.1 - 0.039 14.0 1.0 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 AMK76723.1 - 0.06 13.2 0.1 0.06 13.2 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 AMK76723.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding BNR_2 PF13088.6 AMK76724.1 - 4.2e-05 23.0 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 AMK76724.1 - 0.12 12.4 0.2 1 9.6 0.0 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat Sigma70_r4_2 PF08281.12 AMK76725.1 - 3.8e-15 55.3 0.0 8.3e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK76725.1 - 2.2e-10 40.1 0.2 4.2e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK76725.1 - 2e-08 33.6 0.1 4.5e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AMK76725.1 - 2.1e-05 24.5 0.1 3.5e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AMK76725.1 - 0.016 15.0 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Phage_terminase PF10668.9 AMK76725.1 - 0.044 13.8 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Phage terminase small subunit HTH_24 PF13412.6 AMK76725.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GerE PF00196.19 AMK76725.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 AMK76725.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Ribonuc_red_lgN PF00317.21 AMK76725.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain TonB_dep_Rec PF00593.24 AMK76726.1 - 5.2e-60 204.7 25.7 5.2e-60 204.7 25.7 2.4 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK76726.1 - 9.7e-18 64.7 0.2 2.1e-17 63.6 0.2 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 AMK76726.1 - 2e-10 40.3 2.6 2.2e-10 40.2 0.3 2.4 3 0 0 3 3 3 1 Secretin and TonB N terminus short domain OEP PF02321.18 AMK76727.1 - 1.3e-40 139.3 31.9 5.1e-23 81.9 10.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_3 PF13437.6 AMK76728.1 - 7.8e-12 45.8 0.2 2e-07 31.6 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK76728.1 - 0.00061 19.1 1.2 0.001 18.4 0.3 1.9 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Laminin_I PF06008.14 AMK76728.1 - 0.01 15.5 4.3 0.01 15.5 4.3 1.6 2 0 0 2 2 2 0 Laminin Domain I Biotin_lipoyl_2 PF13533.6 AMK76728.1 - 0.16 11.8 6.1 0.11 12.3 0.5 3.5 2 1 0 2 2 2 0 Biotin-lipoyl like FliJ PF02050.16 AMK76728.1 - 1.9 8.7 13.3 0.8 9.9 0.8 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein ACR_tran PF00873.19 AMK76729.1 - 2.8e-155 518.6 0.0 1.1e-154 516.6 0.0 1.7 1 1 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AMK76729.1 - 1e-06 28.2 13.7 0.0035 16.8 4.8 2.7 3 0 0 3 3 3 2 Protein export membrane protein DUF3142 PF11340.8 AMK76729.1 - 0.023 14.6 0.8 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) HEAT_2 PF13646.6 AMK76730.1 - 9.4e-60 199.0 65.2 8.7e-21 74.1 3.0 4.4 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.22 AMK76730.1 - 2.6e-33 111.2 25.8 1.6e-05 24.7 0.0 10.3 10 0 0 10 10 10 8 HEAT repeat HEAT_PBS PF03130.16 AMK76730.1 - 1.9e-19 68.3 55.0 4.3e-05 23.8 0.6 9.1 9 0 0 9 9 9 7 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 AMK76730.1 - 1.1e-15 57.7 44.8 0.0059 17.1 0.2 10.2 7 2 3 10 10 10 7 HEAT-like repeat Cnd1 PF12717.7 AMK76730.1 - 3.8e-09 36.8 2.9 0.46 10.5 0.1 6.1 2 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 AMK76730.1 - 3.9e-08 33.1 23.7 0.13 12.3 0.0 8.5 8 1 1 9 9 9 3 Armadillo/beta-catenin-like repeat CCDC74_C PF14917.6 AMK76730.1 - 0.016 15.7 0.1 3.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Coiled coil protein 74, C terminal Adaptin_N PF01602.20 AMK76730.1 - 0.047 12.2 1.3 21 3.5 0.0 3.5 1 1 2 4 4 4 0 Adaptin N terminal region Nipped-B_C PF12830.7 AMK76730.1 - 0.051 13.5 0.9 1.9 8.4 0.0 3.7 3 2 1 4 4 4 0 Sister chromatid cohesion C-terminus NMT1_2 PF13379.6 AMK76731.1 - 4.3e-16 59.4 0.1 6.6e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AMK76731.1 - 2e-13 50.8 0.1 1e-12 48.5 0.1 1.9 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 AMK76731.1 - 5.3e-11 42.4 0.0 3.5e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AMK76731.1 - 4.2e-08 33.1 0.0 7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein YhfZ_C PF14503.6 AMK76731.1 - 3.4e-05 23.5 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 YhfZ C-terminal domain LysR_substrate PF03466.20 AMK76731.1 - 0.00062 19.2 0.0 0.067 12.6 0.0 2.2 1 1 1 2 2 2 2 LysR substrate binding domain OpuAC PF04069.12 AMK76731.1 - 0.0079 15.8 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 AMK76731.1 - 0.063 12.7 0.0 0.21 10.9 0.0 1.7 1 1 1 2 2 2 0 NMT1-like family BPD_transp_1 PF00528.22 AMK76732.1 - 5.7e-16 58.8 21.0 5.7e-16 58.8 21.0 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Sulfotransfer_3 PF13469.6 AMK76733.1 - 6.3e-38 131.3 0.1 1.6e-37 130.0 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 AMK76733.1 - 7.1e-07 29.0 0.0 5e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 AMK76733.1 - 0.0003 20.4 0.0 0.2 11.2 0.0 2.9 2 1 0 2 2 2 2 Stf0 sulphotransferase Fer4_7 PF12838.7 AMK76734.1 - 9e-09 35.8 20.5 2.9e-07 31.0 10.0 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK76734.1 - 1.6e-06 28.2 8.3 2.7e-06 27.4 8.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AMK76734.1 - 2.3e-06 27.2 16.6 0.0071 16.1 1.5 3.1 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AMK76734.1 - 2.4e-06 27.4 13.6 1.8e-05 24.6 3.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AMK76734.1 - 0.0001 22.3 12.3 0.001 19.1 12.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK76734.1 - 0.00018 21.6 9.5 0.00028 20.9 9.4 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK76734.1 - 0.0031 17.5 3.3 0.0031 17.5 3.3 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 AMK76734.1 - 0.0048 17.4 1.4 0.0048 17.4 1.4 2.2 1 1 1 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AMK76734.1 - 0.025 15.1 0.7 0.025 15.1 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.6 AMK76734.1 - 0.035 15.0 12.2 0.41 11.6 3.2 2.2 1 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 AMK76734.1 - 0.33 11.5 11.9 0.48 11.0 2.0 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AMK76734.1 - 6.9 7.8 15.0 0.64 11.1 3.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AMK76734.1 - 7.9 7.0 12.9 2.3e+03 -0.9 12.9 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain FAD_binding_2 PF00890.24 AMK76735.1 - 6e-39 134.3 0.6 6e-39 134.3 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 AMK76735.1 - 3e-12 46.6 0.1 6e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AMK76735.1 - 5.3e-10 39.0 3.1 4.5e-05 22.8 0.2 3.6 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AMK76735.1 - 5.4e-06 25.4 0.9 3.3e-05 22.8 0.9 2.1 1 1 0 1 1 1 1 HI0933-like protein DAO PF01266.24 AMK76735.1 - 3.3e-05 23.6 0.2 0.00059 19.5 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AMK76735.1 - 0.00033 20.0 0.7 0.0018 17.6 0.3 2.2 1 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 AMK76735.1 - 0.00062 19.2 1.1 0.0014 18.1 0.5 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 AMK76735.1 - 0.0015 17.5 0.1 0.0025 16.7 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase GMC_oxred_N PF00732.19 AMK76735.1 - 0.0028 17.1 0.3 0.062 12.7 0.1 2.1 1 1 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 AMK76735.1 - 0.0028 16.8 2.9 0.031 13.4 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AMK76735.1 - 0.044 14.0 0.1 0.32 11.3 0.0 2.5 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AMK76735.1 - 0.053 12.6 2.1 0.15 11.1 0.2 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 AMK76735.1 - 0.089 12.1 2.9 0.12 11.7 0.6 2.2 2 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AMK76735.1 - 0.11 11.7 0.8 0.49 9.6 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UTRA PF07702.13 AMK76736.1 - 1.6e-36 125.2 0.6 4.8e-35 120.5 0.3 2.0 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 AMK76736.1 - 2e-21 75.4 0.4 8e-21 73.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 AMK76736.1 - 0.0013 18.4 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 AMK76736.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 AMK76736.1 - 0.015 14.9 0.5 0.21 11.2 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 AMK76736.1 - 0.031 14.0 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AMK76736.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 AMK76736.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF977 PF06163.11 AMK76736.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Sulfatase PF00884.23 AMK76737.1 - 2.7e-79 266.8 0.0 3.5e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AMK76737.1 - 7.1e-06 25.8 0.0 2.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 AMK76737.1 - 9.6e-06 25.4 0.1 0.085 12.8 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function Sulfatase_C PF14707.6 AMK76737.1 - 9.4e-05 23.1 2.4 0.018 15.7 0.1 2.8 2 1 1 3 3 3 2 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 AMK76737.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Calici_MSP PF05752.11 AMK76737.1 - 0.04 13.8 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF229 PF02995.17 AMK76737.1 - 0.11 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Arylsulfotrans PF05935.11 AMK76738.1 - 6.5e-29 101.0 0.0 1.4e-25 90.0 0.0 2.4 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 AMK76738.1 - 1.3e-25 90.4 0.0 1.9e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) TPR_12 PF13424.6 AMK76739.1 - 0.039 14.2 0.5 0.039 14.2 0.5 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 AMK76739.1 - 0.094 12.9 6.5 0.83 9.9 0.5 2.5 1 1 1 2 2 2 0 HemY protein N-terminus DUF1848 PF08902.11 AMK76740.1 - 0.0006 19.6 0.0 0.0006 19.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1848) DUF3646 PF12362.8 AMK76740.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal adh_short PF00106.25 AMK76741.1 - 7.3e-42 143.0 0.0 9.7e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AMK76741.1 - 4.9e-26 91.7 0.0 6.3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AMK76741.1 - 3.9e-09 36.7 0.1 7.8e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 AMK76741.1 - 4e-08 33.0 0.0 6.7e-07 29.0 0.0 2.2 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AMK76741.1 - 5.7e-05 23.1 0.0 7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AMK76741.1 - 0.0075 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 AMK76741.1 - 0.0097 16.5 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 AMK76741.1 - 0.025 15.0 0.0 0.63 10.5 0.0 2.5 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 AMK76741.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 AMK76741.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 AMK76742.1 - 1.8e-28 99.1 0.6 2.8e-28 98.5 0.6 1.3 1 0 0 1 1 1 1 TrkA-N domain Ion_trans PF00520.31 AMK76742.1 - 2.9e-19 69.3 22.5 4.8e-19 68.6 22.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AMK76742.1 - 1.3e-15 57.2 12.0 1.3e-15 57.2 12.0 2.0 2 0 0 2 2 2 1 Ion channel TrkA_C PF02080.21 AMK76742.1 - 5.4e-06 26.1 0.0 2.4e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 TrkA-C domain 2-Hacid_dh_C PF02826.19 AMK76742.1 - 0.0096 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AMK76742.1 - 0.025 14.8 0.1 0.049 13.9 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 AMK76742.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 AMK76742.1 - 0.046 13.9 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 AMK76742.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AMK76742.1 - 0.16 12.6 0.1 0.3 11.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4079 PF13301.6 AMK76742.1 - 0.16 12.1 0.6 0.42 10.7 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Lig_chan PF00060.26 AMK76742.1 - 0.47 10.3 4.4 0.9 9.4 4.4 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel TrkA_N PF02254.18 AMK76743.1 - 1.3e-19 70.5 0.0 2.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 AMK76743.1 - 2.9e-07 30.2 0.1 9.6e-07 28.5 0.1 1.9 2 0 0 2 2 2 1 TrkA-C domain ADH_zinc_N PF00107.26 AMK76743.1 - 0.00041 20.3 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase DsbB PF02600.16 AMK76744.1 - 7e-38 130.4 10.3 7.9e-38 130.2 10.3 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB VKOR PF07884.14 AMK76744.1 - 0.67 10.1 6.9 9.1 6.5 2.4 2.3 2 1 0 2 2 2 0 Vitamin K epoxide reductase family PriA_3primeBD PF17764.1 AMK76745.1 - 8.4e-29 99.3 0.0 1.7e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 AMK76745.1 - 9.4e-24 84.1 0.1 3.8e-23 82.1 0.0 2.2 2 0 0 2 2 1 1 Primosomal protein N C-terminal domain ResIII PF04851.15 AMK76745.1 - 1.1e-13 51.5 0.0 1.8e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 AMK76745.1 - 4.1e-13 49.7 0.4 4.1e-07 30.3 0.1 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 AMK76745.1 - 1.2e-11 44.6 0.1 2.7e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase PriA_CRR PF18319.1 AMK76745.1 - 2e-10 40.5 4.5 2e-10 40.5 4.5 3.3 4 0 0 4 4 3 1 PriA DNA helicase Cys-rich region (CRR) domain AAA_30 PF13604.6 AMK76745.1 - 4e-05 23.4 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mtr2 PF10429.9 AMK76745.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 TrwB_AAD_bind PF10412.9 AMK76745.1 - 0.043 12.7 0.0 0.093 11.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain HypA PF01155.19 AMK76745.1 - 0.084 12.9 3.5 0.21 11.6 3.5 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 AMK76745.1 - 0.11 12.2 1.7 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF1451 PF07295.11 AMK76745.1 - 0.15 12.1 2.7 0.4 10.7 2.7 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-CHY PF05495.12 AMK76745.1 - 0.15 12.5 3.7 0.31 11.6 3.7 1.4 1 0 0 1 1 1 0 CHY zinc finger PIF1 PF05970.14 AMK76745.1 - 0.17 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase GAIN PF16489.5 AMK76745.1 - 0.17 11.3 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain zinc-ribbons_6 PF07191.12 AMK76745.1 - 1.1 9.3 7.6 0.21 11.6 4.0 1.6 2 0 0 2 2 1 0 zinc-ribbons ArAE_1 PF06081.11 AMK76746.1 - 0.06 13.5 0.4 0.17 12.0 0.4 1.7 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 DUF981 PF06168.11 AMK76746.1 - 4 7.3 12.3 0.12 12.2 4.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF981) Nitroreductase PF00881.24 AMK76747.1 - 3.5e-23 82.5 0.0 5.7e-23 81.8 0.0 1.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AMK76747.1 - 0.0057 16.2 0.0 0.043 13.4 0.0 2.0 2 0 0 2 2 2 1 Putative TM nitroreductase NLPC_P60 PF00877.19 AMK76748.1 - 9.7e-30 102.7 0.0 1.2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 AMK76748.1 - 0.0016 18.6 0.0 1 9.5 0.0 2.2 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LRAT PF04970.13 AMK76748.1 - 0.0046 17.3 0.0 0.0061 16.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF1175 PF06672.11 AMK76748.1 - 0.01 15.5 0.1 0.66 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) CHAP PF05257.16 AMK76748.1 - 0.019 15.6 0.0 0.028 15.0 0.0 1.4 1 0 0 1 1 1 0 CHAP domain DUF5392 PF17370.2 AMK76749.1 - 0.15 12.1 2.5 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5392) IMS PF00817.20 AMK76750.1 - 1.9e-49 167.5 0.0 2.9e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 AMK76750.1 - 1.2e-15 58.2 0.7 8.4e-15 55.5 0.5 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AMK76750.1 - 9.2e-06 25.7 0.0 2.6e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 AMK76750.1 - 0.019 14.8 0.1 0.051 13.4 0.1 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HTH_45 PF14947.6 AMK76750.1 - 0.085 12.9 0.6 5.6 7.0 0.4 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DUF4389 PF14333.6 AMK76751.1 - 3.5e-27 94.1 2.2 4e-27 93.9 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4389) DUF2333 PF10095.9 AMK76752.1 - 5e-140 466.2 0.0 5.6e-140 466.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) YcgL PF05166.13 AMK76753.1 - 3e-32 110.8 0.2 3.8e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 YcgL domain CPBP PF02517.16 AMK76754.1 - 1.8e-17 63.5 5.7 1.8e-17 63.5 5.7 1.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF1746 PF08508.10 AMK76754.1 - 0.033 14.5 0.4 0.064 13.6 0.4 1.5 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) DUF4271 PF14093.6 AMK76755.1 - 0.036 14.0 3.0 0.043 13.7 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) IMPDH PF00478.25 AMK76756.1 - 2.7e-166 552.8 11.7 3.2e-166 552.5 11.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 AMK76756.1 - 6.5e-19 68.1 8.2 5e-12 46.1 0.7 3.1 4 0 0 4 4 4 2 CBS domain NMO PF03060.15 AMK76756.1 - 2e-16 60.3 15.4 3.3e-09 36.6 9.8 2.3 1 1 1 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 AMK76756.1 - 1.3e-08 34.2 18.4 9.1e-08 31.5 18.4 2.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AMK76756.1 - 0.00011 21.8 6.7 0.017 14.6 0.1 3.4 2 1 1 3 3 3 2 Histidine biosynthesis protein Glu_synthase PF01645.17 AMK76756.1 - 0.0012 18.0 8.0 0.0012 18.0 8.0 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase QRPTase_C PF01729.19 AMK76756.1 - 0.033 14.0 3.2 0.22 11.3 0.4 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 AMK76756.1 - 0.16 11.2 11.2 0.06 12.6 3.4 2.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 AMK76756.1 - 0.29 10.5 5.5 0.3 10.5 0.1 3.1 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 AMK76756.1 - 8.1 5.6 14.7 0.29 10.3 0.9 3.4 3 1 1 4 4 4 0 Dihydroorotate dehydrogenase Methyltransf_23 PF13489.6 AMK76757.1 - 7.8e-18 64.9 0.0 1.4e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK76757.1 - 4.8e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76757.1 - 1.4e-10 41.8 0.0 4.5e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK76757.1 - 3.7e-09 36.6 0.0 9.9e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76757.1 - 1.3e-08 35.4 0.0 4.4e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 AMK76757.1 - 0.00029 19.9 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.12 AMK76757.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 AMK76757.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 AMK76757.1 - 0.0051 16.2 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TF_Zn_Ribbon PF08271.12 AMK76757.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding GMP_synt_C PF00958.22 AMK76758.1 - 9.9e-43 144.1 0.0 2e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 AMK76758.1 - 9.6e-39 133.1 0.0 1.5e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 AMK76758.1 - 3.8e-13 49.1 0.4 1.2e-09 37.7 0.2 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AMK76758.1 - 4.6e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AMK76758.1 - 2.1e-05 23.5 0.2 9.6e-05 21.3 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 AMK76758.1 - 0.0005 19.8 0.2 0.00094 18.9 0.2 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 AMK76758.1 - 0.00081 18.9 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 AMK76758.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 AMK76758.1 - 0.032 14.0 0.1 0.066 13.0 0.0 1.6 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.19 AMK76758.1 - 0.069 12.4 0.1 0.28 10.4 0.1 1.9 2 0 0 2 2 2 0 Arginosuccinate synthase DJ-1_PfpI PF01965.24 AMK76758.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Phage_integrase PF00589.22 AMK76759.1 - 1.2e-11 44.8 0.2 1.6e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Phage integrase family Trp_repressor PF01371.19 AMK76759.1 - 0.00062 19.8 0.1 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 Trp repressor protein HTH_Tnp_ISL3 PF13542.6 AMK76759.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_19 PF12844.7 AMK76759.1 - 0.014 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AMK76759.1 - 0.037 13.7 0.2 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF3071 PF11268.8 AMK76759.1 - 0.063 13.3 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Pentapeptide PF00805.22 AMK76760.1 - 1.4e-37 126.8 36.0 1.6e-10 40.4 3.5 7.7 4 2 5 9 9 9 8 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 AMK76760.1 - 2.6e-21 75.5 3.2 9.4e-09 35.3 0.3 4.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AMK76760.1 - 3.8e-14 52.5 0.6 1.8e-05 24.8 0.1 5.3 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) DUF4148 PF13663.6 AMK76760.1 - 0.0062 16.7 0.8 0.016 15.4 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4148) DNA_ligase_OB PF03120.16 AMK76760.1 - 0.044 13.7 0.9 26 4.8 0.2 3.6 2 2 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain CfAFP PF05264.11 AMK76760.1 - 0.082 12.9 0.1 2.4 8.1 0.0 2.4 1 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) AA_permease_2 PF13520.6 AMK76761.1 - 1.1e-51 176.1 45.7 1.4e-51 175.7 45.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 AMK76761.1 - 4.9e-39 134.2 44.1 6.2e-39 133.9 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 AMK76761.1 - 8.9e-18 64.1 4.2 8.9e-18 64.1 4.2 3.9 4 1 0 4 4 4 1 C-terminus of AA_permease EF-hand_13 PF17958.1 AMK76762.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain UDPG_MGDP_dh_N PF03721.14 AMK76764.1 - 1e-67 227.4 0.1 1.5e-67 226.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 AMK76764.1 - 2.5e-39 133.4 0.0 5e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 AMK76764.1 - 1.3e-31 109.1 0.1 5.1e-31 107.2 0.0 2.0 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 AMK76764.1 - 0.00032 20.4 0.0 0.0016 18.1 0.0 2.1 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 AMK76764.1 - 0.0018 18.2 1.0 0.0059 16.5 0.0 2.3 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 AMK76764.1 - 0.0035 17.6 0.0 0.15 12.3 0.0 2.6 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 AMK76764.1 - 0.0048 17.1 0.5 4.8 7.3 0.1 3.4 4 0 0 4 4 4 1 NAD binding domain of 6-phosphogluconate dehydrogenase CdhD PF03599.16 AMK76764.1 - 0.026 13.2 0.1 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NAD_binding_2 PF03446.15 AMK76765.1 - 4.1e-49 166.8 5.9 4.1e-49 166.8 5.9 2.2 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 AMK76765.1 - 3.8e-33 114.3 0.5 3.8e-33 114.3 0.5 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 AMK76765.1 - 1.6e-12 47.9 0.8 4.4e-12 46.4 0.8 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 AMK76765.1 - 1.7e-09 37.8 1.3 1.7e-09 37.8 1.3 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 AMK76765.1 - 1e-07 32.8 0.7 2.6e-07 31.5 0.5 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold PDH PF02153.17 AMK76765.1 - 7.6e-07 28.4 1.1 1.1e-06 27.9 1.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 AMK76765.1 - 7.6e-07 28.7 0.6 7.6e-07 28.7 0.6 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AMK76765.1 - 0.00043 20.2 3.3 0.00044 20.2 1.4 2.1 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 AMK76765.1 - 0.0082 15.8 2.5 0.025 14.2 2.5 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 AMK76765.1 - 0.01 15.4 0.5 0.01 15.4 0.5 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AMK76765.1 - 0.018 14.4 6.2 0.015 14.6 5.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 AMK76765.1 - 0.024 14.9 1.7 0.12 12.6 1.7 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 AMK76765.1 - 0.058 13.8 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 AMK76765.1 - 0.059 12.9 9.3 0.079 12.5 3.4 2.5 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 AMK76765.1 - 8.6 5.6 11.8 7.7 5.8 1.5 2.3 1 1 1 2 2 2 0 ThiF family Lipase_GDSL_2 PF13472.6 AMK76766.1 - 7.5e-22 78.6 0.1 1.5e-21 77.6 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 AMK76766.1 - 6.6e-13 49.1 0.1 2.3e-12 47.3 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 AMK76766.1 - 0.0008 19.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family AHJR-like PF18743.1 AMK76766.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 REase_AHJR-like Orn_Arg_deC_N PF02784.16 AMK76767.1 - 7.9e-46 156.4 0.2 1.2e-45 155.8 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 AMK76767.1 - 2.9e-17 62.7 2.9 9.1e-17 61.1 2.9 1.9 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 AMK76767.1 - 1.6e-13 51.0 4.2 2.6e-13 50.3 1.0 2.8 2 0 0 2 2 2 1 Arginine decarboxylase C-terminal helical extension Spermine_synth PF01564.17 AMK76768.1 - 4.6e-51 172.9 0.0 6.3e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 AMK76768.1 - 2.8e-15 55.9 0.1 5.8e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain DUF4248 PF14053.6 AMK76768.1 - 0.11 12.5 0.0 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) GGDEF PF00990.21 AMK76769.1 - 1e-47 161.9 1.6 1.4e-47 161.4 1.6 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Yop-YscD_cpl PF16697.5 AMK76769.1 - 8.2e-24 83.7 0.1 1.6e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 AMK76769.1 - 3.5e-18 65.7 0.3 7.1e-18 64.7 0.3 1.5 1 0 0 1 1 1 1 FHA domain GGDEF_2 PF17853.1 AMK76769.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain OmpA PF00691.20 AMK76771.1 - 6.2e-12 45.7 0.5 1.5e-11 44.5 0.1 1.8 2 0 0 2 2 2 1 OmpA family ComFB PF10719.9 AMK76773.1 - 1.1e-18 67.0 0.4 1.3e-18 66.9 0.4 1.0 1 0 0 1 1 1 1 Late competence development protein ComFB MacB_PCD PF12704.7 AMK76774.1 - 1.2e-30 107.3 1.5 1.2e-30 107.3 1.5 1.8 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AMK76774.1 - 2.4e-13 50.3 8.0 2.4e-13 50.3 8.0 3.2 2 1 1 3 3 3 2 FtsX-like permease family MacB_PCD PF12704.7 AMK76775.1 - 2.9e-30 106.1 3.5 7.5e-30 104.7 0.2 2.2 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AMK76775.1 - 1.2e-08 35.3 2.2 1.2e-08 35.3 2.2 2.9 3 0 0 3 3 3 1 FtsX-like permease family Response_reg PF00072.24 AMK76776.1 - 2e-28 98.8 0.0 3.1e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK76776.1 - 2.9e-20 72.1 0.9 2.1e-19 69.4 0.2 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal DUF4118 PF13493.6 AMK76777.1 - 2.7e-28 97.9 5.2 4.6e-28 97.1 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 AMK76777.1 - 4.3e-22 78.7 0.0 1e-21 77.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK76777.1 - 3.6e-12 46.1 2.0 6.9e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AMK76777.1 - 0.0019 18.1 0.1 0.12 12.3 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK76777.1 - 0.048 13.5 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK76777.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 GHKL domain CitMHS PF03600.16 AMK76778.1 - 1.7e-42 145.7 22.6 2.6e-42 145.1 22.6 1.3 1 0 0 1 1 1 1 Citrate transporter BBP2 PF07642.11 AMK76779.1 - 4.9e-81 272.6 14.8 5.7e-81 272.4 14.8 1.0 1 0 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 DUF2490 PF10677.9 AMK76779.1 - 0.099 12.6 3.5 0.78 9.7 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2490) EamA PF00892.20 AMK76781.1 - 5.8e-17 62.2 37.9 4.1e-12 46.4 12.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Haem_bd PF14376.6 AMK76782.1 - 0.0018 18.2 0.3 0.008 16.1 0.1 1.9 1 1 1 2 2 2 1 Haem-binding domain Paired_CXXCH_1 PF09699.10 AMK76782.1 - 0.021 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_CBB3 PF13442.6 AMK76782.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III SpoIIAA-like PF11964.8 AMK76783.1 - 0.0033 18.5 0.1 0.0039 18.2 0.1 1.2 1 0 0 1 1 1 1 SpoIIAA-like ABC_tran PF00005.27 AMK76784.1 - 1.6e-33 116.2 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK76784.1 - 3.3e-08 33.7 0.5 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK76784.1 - 6.2e-07 29.1 1.1 0.00022 20.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AMK76784.1 - 1.3e-06 28.9 0.1 2e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AMK76784.1 - 0.00011 22.4 0.1 0.00029 21.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK76784.1 - 0.00028 20.6 0.1 0.00054 19.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK76784.1 - 0.0013 18.7 0.1 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 AMK76784.1 - 0.029 14.9 0.0 0.069 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AMK76784.1 - 0.045 13.5 0.1 0.6 9.8 0.0 2.3 2 1 1 3 3 3 0 IstB-like ATP binding protein APS_kinase PF01583.20 AMK76784.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 AMK76784.1 - 0.093 12.9 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AMK76784.1 - 0.1 12.1 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 AMK76784.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 AMK76784.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.9 3 0 0 3 3 3 0 NACHT domain ATPase_2 PF01637.18 AMK76784.1 - 0.18 11.7 0.1 0.48 10.3 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 AMK76784.1 - 0.2 11.7 0.5 0.45 10.6 0.3 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase HlyD_D23 PF16576.5 AMK76785.1 - 1.8e-18 66.6 2.6 4.5e-18 65.3 2.6 1.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76785.1 - 4.8e-16 59.4 1.6 6.9e-11 42.8 0.0 3.2 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK76785.1 - 3.8e-09 36.2 11.5 1.8e-08 34.1 3.3 3.1 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76785.1 - 1.3e-06 28.1 0.1 0.00077 19.2 0.1 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.20 AMK76785.1 - 2.4e-05 24.1 0.0 0.00046 20.0 0.0 2.9 3 1 0 3 3 3 1 HlyD membrane-fusion protein of T1SS Peptidase_M23 PF01551.22 AMK76785.1 - 0.00016 21.8 0.5 0.066 13.4 0.1 2.5 2 0 0 2 2 2 2 Peptidase family M23 PTS_EIIA_1 PF00358.20 AMK76785.1 - 0.002 17.9 0.2 0.035 13.9 0.0 2.4 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 AMK76785.1 - 0.0027 17.6 1.5 0.47 10.4 0.1 3.5 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 AMK76785.1 - 0.018 14.7 0.1 0.047 13.3 0.1 1.7 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain LysR_substrate PF03466.20 AMK76785.1 - 0.039 13.3 0.4 0.12 11.7 0.4 1.8 1 0 0 1 1 1 0 LysR substrate binding domain Peptidase_M3_N PF08439.10 AMK76785.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Oligopeptidase F YqfD PF06898.11 AMK76785.1 - 0.18 10.6 2.6 0.51 9.1 1.0 2.4 2 1 0 2 2 2 0 Putative stage IV sporulation protein YqfD Aldolase_II PF00596.21 AMK76786.1 - 1.8e-40 138.9 0.0 2.1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ARD PF03079.14 AMK76787.1 - 2.1e-40 138.5 0.0 2.5e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 AMK76787.1 - 1.7e-06 27.6 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 AMK76787.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 AMK76787.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HAD_2 PF13419.6 AMK76788.1 - 0.0005 20.2 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AMK76788.1 - 0.0025 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 AMK76788.1 - 0.015 15.6 0.0 0.049 13.9 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RimK PF08443.11 AMK76789.1 - 5e-69 231.7 0.0 6.1e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AMK76789.1 - 2.6e-41 139.9 0.1 4.6e-41 139.1 0.1 1.4 1 0 0 1 1 1 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AMK76789.1 - 3.5e-17 62.3 0.1 6.2e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 AMK76789.1 - 2.6e-09 36.7 0.1 0.0024 17.2 0.1 3.1 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 AMK76789.1 - 4.4e-09 36.6 0.0 7.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 AMK76789.1 - 3.5e-05 23.2 0.0 0.42 9.8 0.1 3.1 1 1 2 3 3 3 2 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 AMK76789.1 - 9.8e-05 22.0 0.2 0.0015 18.1 0.2 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus R2K_3 PF14243.6 AMK76789.1 - 0.0015 18.6 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 ATP-grasp_2 PF08442.10 AMK76789.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 AMK76789.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 AMK76789.1 - 0.023 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GSH-S_N PF02951.14 AMK76789.1 - 0.099 12.8 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain ExbD PF02472.16 AMK76790.1 - 1.5e-28 99.6 0.4 1.6e-28 99.5 0.4 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 AMK76790.1 - 0.055 13.7 0.4 0.088 13.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) MotA_ExbB PF01618.16 AMK76791.1 - 4e-37 126.8 0.1 5.2e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Tricorn_C1 PF14684.6 AMK76791.1 - 0.34 11.0 1.7 0.64 10.1 0.9 1.8 2 0 0 2 2 2 0 Tricorn protease C1 domain Phage_holin_2_4 PF16082.5 AMK76791.1 - 0.54 10.0 4.2 8.3 6.2 0.3 2.6 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like TonB_C PF03544.14 AMK76792.1 - 4.9e-23 81.4 0.0 9.9e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AMK76792.1 - 0.0002 21.5 0.0 0.0002 21.5 0.0 2.0 2 0 0 2 2 2 1 TonB C terminal FAA_hydrolase PF01557.18 AMK76794.1 - 5.2e-74 248.6 0.0 6.6e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AMK76794.1 - 0.00053 20.8 0.1 0.0015 19.4 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2437) Chorismate_bind PF00425.18 AMK76795.1 - 3.5e-99 331.5 0.0 4.9e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AMK76795.1 - 1.6e-35 122.3 0.0 4.3e-32 111.3 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region GATase PF00117.28 AMK76796.1 - 9.1e-56 188.6 0.1 1e-55 188.5 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AMK76796.1 - 3.9e-09 36.6 0.7 1.9e-08 34.3 0.7 1.9 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 AMK76796.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 SNO glutamine amidotransferase family Peripla_BP_2 PF01497.18 AMK76796.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein HI0933_like PF03486.14 AMK76797.1 - 2.7e-107 359.0 0.0 3e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 AMK76797.1 - 0.0019 17.6 0.0 0.35 10.1 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Glycos_transf_3 PF00591.21 AMK76798.1 - 3.6e-97 324.9 2.3 4.8e-97 324.5 2.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AMK76798.1 - 1e-20 73.3 2.2 3.4e-20 71.7 2.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain MRP-S32 PF10210.9 AMK76799.1 - 0.44 11.1 2.4 3 8.5 0.1 2.4 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 DUF772 PF05598.11 AMK76801.1 - 3.2e-22 78.3 0.7 3e-21 75.2 0.3 2.7 2 1 1 3 3 3 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AMK76801.1 - 6.8e-14 52.0 0.5 1.9e-13 50.6 0.5 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK76801.1 - 5.9e-08 33.0 0.1 1.5e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AMK76801.1 - 2.8e-05 24.4 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76801.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain IGPS PF00218.21 AMK76802.1 - 2.1e-95 318.8 0.0 2.3e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase TauE PF01925.19 AMK76803.1 - 3.6e-46 157.7 31.5 4.2e-46 157.5 31.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Trp_oprn_chp PF09534.10 AMK76803.1 - 0.091 12.5 4.8 0.17 11.7 4.0 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UPF0016 PF01169.19 AMK76803.1 - 0.13 12.6 0.3 0.13 12.6 0.3 3.7 4 1 0 4 4 4 0 Uncharacterized protein family UPF0016 EMP70 PF02990.16 AMK76803.1 - 0.26 9.9 0.8 0.34 9.5 0.8 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 GTP_EFTU PF00009.27 AMK76804.1 - 4e-56 189.6 0.0 8.7e-56 188.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AMK76804.1 - 8.1e-23 80.3 0.0 2.2e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AMK76804.1 - 1.3e-08 35.1 1.5 2e-08 34.5 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AMK76804.1 - 1.3e-06 28.5 0.1 3.9e-06 26.9 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AMK76804.1 - 4.5e-05 23.5 0.1 0.00011 22.2 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 AMK76804.1 - 0.0008 18.8 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 AMK76804.1 - 0.036 13.5 0.1 0.094 12.1 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 AMK76804.1 - 0.055 13.0 0.0 0.54 9.8 0.0 2.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.16 AMK76804.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Rhodanese PF00581.20 AMK76805.1 - 5.2e-10 39.8 0.0 6.3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF442 PF04273.13 AMK76805.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 1 1 2 2 2 0 Putative phosphatase (DUF442) TehB PF03848.14 AMK76806.1 - 8.5e-12 44.9 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 AMK76806.1 - 2.9e-09 37.0 0.0 5.2e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76806.1 - 4.7e-09 36.8 0.0 7.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK76806.1 - 2.7e-06 27.9 0.0 4.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76806.1 - 2.3e-05 25.1 0.1 0.0001 22.9 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 AMK76806.1 - 7.3e-05 22.4 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AMK76806.1 - 0.00061 19.6 0.0 0.00076 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK76806.1 - 0.0024 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 AMK76806.1 - 0.0028 17.2 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 AMK76806.1 - 0.035 13.7 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 AMK76806.1 - 0.047 13.3 0.1 0.29 10.7 0.0 1.9 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F TPMT PF05724.11 AMK76806.1 - 0.07 12.8 0.1 0.25 11.0 0.1 2.0 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) N2227 PF07942.12 AMK76806.1 - 0.15 11.2 0.2 0.63 9.2 0.0 1.8 1 1 1 2 2 2 0 N2227-like protein LysR_substrate PF03466.20 AMK76807.1 - 4.9e-49 166.5 0.0 6.6e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK76807.1 - 2.4e-18 65.9 0.5 3.9e-18 65.1 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PRA-PH PF01503.17 AMK76808.1 - 2.9e-17 62.9 0.2 3.4e-17 62.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 AMK76808.1 - 0.01 16.0 0.8 0.032 14.4 0.2 1.9 1 1 1 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain MttA_Hcf106 PF02416.16 AMK76809.1 - 5.3e-16 57.7 0.1 5.8e-16 57.6 0.1 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family HEPN_Toprim_N PF18871.1 AMK76809.1 - 0.092 12.7 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 MttA_Hcf106 PF02416.16 AMK76810.1 - 4.2e-07 29.2 1.7 6.4e-07 28.6 1.5 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family TatC PF00902.18 AMK76811.1 - 9.4e-63 211.8 24.6 1.1e-62 211.5 24.6 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Ala_racemase_N PF01168.20 AMK76812.1 - 5.7e-27 94.8 0.0 7.1e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DALR_1 PF05746.15 AMK76813.1 - 5.8e-33 113.6 4.2 7.8e-33 113.2 2.2 2.1 2 1 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 AMK76813.1 - 1.8e-26 92.5 0.1 3.6e-25 88.4 0.4 2.6 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1d PF00750.19 AMK76813.1 - 1.7e-21 76.6 0.7 1.2e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1g PF09334.11 AMK76813.1 - 2.3e-05 23.4 0.6 0.15 10.7 0.1 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 AMK76813.1 - 0.0017 17.3 0.0 0.15 11.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) SPOR PF05036.13 AMK76814.1 - 4.1e-11 43.1 0.0 8.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Sporulation related domain DUF2007 PF09413.10 AMK76814.1 - 0.025 14.7 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein HlyU PF10115.9 AMK76814.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator HlyU FlgO PF17680.1 AMK76815.1 - 1.3e-21 76.7 0.0 1.7e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 FlgO protein FerA PF08165.11 AMK76815.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 FerA (NUC095) domain LPAM_1 PF08139.12 AMK76815.1 - 0.038 14.5 1.0 0.065 13.7 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Asparaginase PF00710.20 AMK76816.1 - 1.3e-27 96.6 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 AMK76816.1 - 0.0078 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DHFR_1 PF00186.19 AMK76817.1 - 2.7e-58 196.2 0.0 3.1e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase PBP_like_2 PF12849.7 AMK76818.1 - 4.9e-36 124.9 1.1 8.6e-36 124.0 1.1 1.4 1 1 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AMK76818.1 - 1.7e-11 43.6 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AMK76818.1 - 2.5e-06 27.4 0.1 1.4e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Phage_T4_gp36 PF03903.13 AMK76818.1 - 0.11 12.5 2.1 7.3 6.6 0.0 2.5 3 0 0 3 3 3 0 Phage T4 tail fibre BPD_transp_1 PF00528.22 AMK76819.1 - 1.7e-10 40.9 28.7 1.7e-10 40.9 28.7 2.7 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component LVIVD PF08309.11 AMK76819.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat BPD_transp_1 PF00528.22 AMK76820.1 - 1.1e-18 67.6 10.7 1.1e-18 67.6 10.7 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component WXG100 PF06013.12 AMK76820.1 - 0.17 12.2 5.8 0.13 12.6 4.2 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG FlxA PF14282.6 AMK76820.1 - 2 8.4 9.9 1.6 8.8 8.4 1.5 1 1 0 1 1 1 0 FlxA-like protein ABC_tran PF00005.27 AMK76821.1 - 9.4e-30 103.9 0.0 1.4e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK76821.1 - 1.8e-10 41.2 0.0 4.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK76821.1 - 8.6e-08 31.9 0.1 6.4e-07 29.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AMK76821.1 - 0.00012 22.3 0.0 0.00034 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AMK76821.1 - 0.00018 21.4 0.1 0.00048 20.1 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AMK76821.1 - 0.0014 19.1 0.0 0.0033 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AMK76821.1 - 0.0015 19.1 0.0 0.0048 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AMK76821.1 - 0.0018 18.0 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AMK76821.1 - 0.0034 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 AMK76821.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_ATPase PF09818.9 AMK76821.1 - 0.014 14.2 0.0 4.2 6.1 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 AMK76821.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 AMK76821.1 - 0.018 13.8 0.0 0.065 12.0 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.22 AMK76821.1 - 0.029 13.6 0.0 0.044 13.0 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA PF00004.29 AMK76821.1 - 0.051 14.0 0.1 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AMK76821.1 - 0.073 13.0 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF5442 PF17514.2 AMK76821.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) AAA_25 PF13481.6 AMK76821.1 - 0.18 11.4 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoU PF01895.19 AMK76822.1 - 5e-41 139.1 10.9 2e-22 79.4 2.0 2.2 2 0 0 2 2 2 2 PhoU domain SCAPER_N PF16501.5 AMK76822.1 - 0.94 9.5 3.8 2.1 8.4 0.3 2.6 2 1 1 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum SKA2 PF16740.5 AMK76822.1 - 1.7 8.4 6.5 10 5.9 1.4 2.6 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF1451 PF07295.11 AMK76822.1 - 2.4 8.2 9.0 0.67 10.0 1.5 2.7 1 1 1 3 3 3 0 Zinc-ribbon containing domain KIP1 PF07765.12 AMK76822.1 - 2.7 8.2 6.6 1.6 8.9 0.7 3.3 2 2 2 4 4 4 0 KIP1-like protein HATPase_c PF02518.26 AMK76823.1 - 9.8e-29 100.1 0.3 2.8e-28 98.6 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE8 PF17152.4 AMK76823.1 - 9.6e-17 61.1 0.1 2.6e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 Periplasmic sensor domain HisKA PF00512.25 AMK76823.1 - 2.8e-15 56.1 0.5 8.6e-15 54.5 0.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK76823.1 - 6.8e-11 42.4 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 AMK76823.1 - 4.1e-06 26.8 0.2 2.9e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK76823.1 - 0.00039 20.3 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2222 PF09984.9 AMK76823.1 - 0.0064 16.4 0.2 0.087 12.7 0.2 2.4 1 1 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) SMP_2 PF10144.9 AMK76823.1 - 0.0083 15.8 1.3 0.1 12.2 0.9 2.5 2 0 0 2 2 2 1 Bacterial virulence factor haemolysin Nrap_D5 PF17406.2 AMK76823.1 - 0.031 14.0 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 DUF4154 PF13689.6 AMK76824.1 - 5.6e-33 114.2 0.0 6.8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like TonB_dep_Rec PF00593.24 AMK76825.1 - 3.1e-36 126.3 29.2 4.1e-36 125.9 29.2 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK76825.1 - 1.7e-20 73.6 0.0 3.5e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK76825.1 - 1.3e-09 37.5 5.2 7.2e-09 35.1 1.8 2.2 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family DCP2 PF05026.13 AMK76825.1 - 0.074 13.4 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 Dcp2, box A domain OMP_b-brl PF13505.6 AMK76825.1 - 0.74 9.9 16.1 0.43 10.7 0.2 3.5 2 2 1 3 3 3 0 Outer membrane protein beta-barrel domain Methyltransf_11 PF08241.12 AMK76826.1 - 5.8e-25 87.8 0.0 1.1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK76826.1 - 4.4e-21 75.4 0.0 8.7e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK76826.1 - 1.3e-17 63.9 0.0 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AMK76826.1 - 1.4e-17 64.0 0.0 1.8e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK76826.1 - 2.5e-17 63.1 0.0 3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK76826.1 - 9.7e-16 58.3 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 AMK76826.1 - 0.00026 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF2194 PF09960.9 AMK76826.1 - 0.00034 19.1 0.0 0.00039 18.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) UPF0020 PF01170.18 AMK76826.1 - 0.00074 19.3 0.0 0.00087 19.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CRF PF00473.17 AMK76826.1 - 0.0037 17.3 1.9 0.018 15.1 0.9 2.2 2 0 0 2 2 2 1 Corticotropin-releasing factor family Methyltransf_2 PF00891.18 AMK76826.1 - 0.054 12.8 0.0 0.071 12.4 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 AMK76826.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tim44 PF04280.15 AMK76827.1 - 6.1e-16 58.8 0.4 3.1e-15 56.5 0.4 1.9 1 1 0 1 1 1 1 Tim44-like domain Phage_holin_3_6 PF07332.11 AMK76827.1 - 0.18 11.9 3.6 0.15 12.1 0.4 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1180 PF06679.12 AMK76827.1 - 0.83 10.1 2.7 2.7 8.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SARAF PF06682.12 AMK76827.1 - 1.3 8.6 12.1 2.6 7.6 4.6 2.1 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis OEP PF02321.18 AMK76829.1 - 6.2e-22 78.3 21.7 8.2e-13 48.6 2.6 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_D23 PF16576.5 AMK76830.1 - 2.9e-36 124.7 0.1 4.9e-36 124.0 0.0 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76830.1 - 1.6e-14 54.5 0.3 2.2e-11 44.4 0.0 3.2 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK76830.1 - 2.7e-10 39.9 0.4 1.3e-08 34.5 0.1 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_2 PF12700.7 AMK76830.1 - 7.8e-06 24.9 0.0 4.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D4 PF16572.5 AMK76830.1 - 0.0002 21.1 0.3 0.009 15.9 0.1 2.8 2 0 0 2 2 2 1 Long alpha hairpin domain of cation efflux system protein, CusB Biotin_lipoyl PF00364.22 AMK76830.1 - 0.01 15.7 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme RnfC_N PF13375.6 AMK76830.1 - 0.018 15.0 0.2 0.38 10.7 0.1 2.7 2 2 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 AMK76830.1 - 0.045 13.4 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain ACR_tran PF00873.19 AMK76831.1 - 1.3e-288 960.0 17.4 1.5e-288 959.8 17.4 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family LRV PF01816.17 AMK76831.1 - 6.8 7.3 5.8 62 4.3 0.0 4.1 3 0 0 3 3 3 0 Leucine rich repeat variant DUF3240 PF11582.8 AMK76832.1 - 1.3e-18 67.0 0.0 1.3e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) DUF3240 PF11582.8 AMK76833.1 - 4.7e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) DUF3470 PF11953.8 AMK76834.1 - 6.2e-21 74.1 1.1 8.6e-21 73.6 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 AMK76834.1 - 1.4e-09 37.4 19.7 4e-07 29.6 4.8 3.1 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_10 PF13237.6 AMK76834.1 - 5.8e-08 32.7 8.1 4.4e-05 23.5 0.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK76834.1 - 4.3e-07 29.7 19.3 3.9e-05 23.5 4.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AMK76834.1 - 6.6e-07 29.4 11.7 0.00031 20.8 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK76834.1 - 3.1e-06 27.7 14.8 1.3e-05 25.7 14.8 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK76834.1 - 3.1e-06 28.0 11.5 0.0003 21.6 1.3 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AMK76834.1 - 6.6e-06 25.9 13.3 0.0072 16.4 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AMK76834.1 - 8e-05 23.1 6.6 0.0026 18.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK76834.1 - 9.6e-05 22.5 25.2 0.0024 18.0 14.8 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK76834.1 - 0.0002 21.7 7.0 0.0051 17.2 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK76834.1 - 0.00024 21.4 13.9 0.074 13.6 1.4 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_11 PF13247.6 AMK76834.1 - 0.047 13.8 5.9 0.07 13.3 5.9 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AMK76834.1 - 0.51 11.4 18.8 2.1 9.5 6.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AMK76834.1 - 0.84 10.2 18.8 0.94 10.1 7.2 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 AMK76834.1 - 5.3 7.2 9.7 1 9.5 1.2 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S GTP_EFTU PF00009.27 AMK76835.1 - 6.3e-58 195.5 0.0 9.8e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AMK76835.1 - 1.3e-42 144.4 0.0 2.5e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AMK76835.1 - 1.9e-29 101.5 0.0 3.8e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AMK76835.1 - 4.2e-27 94.0 0.0 1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AMK76835.1 - 2e-16 60.2 0.2 5.3e-16 58.8 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AMK76835.1 - 0.032 14.3 0.0 0.098 12.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-grasp_4 PF13535.6 AMK76835.1 - 0.12 11.9 0.6 0.3 10.7 0.6 1.6 1 0 0 1 1 1 0 ATP-grasp domain ApbA PF02558.16 AMK76836.1 - 2.6e-33 114.8 0.0 3.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 AMK76836.1 - 4.2e-27 94.8 0.0 6.7e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_3 PF01494.19 AMK76836.1 - 0.0044 16.3 0.1 0.0064 15.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 AMK76836.1 - 0.0062 17.1 0.2 0.012 16.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 AMK76836.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 AMK76836.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 AMK76836.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Bac_DnaA PF00308.18 AMK76837.1 - 8.9e-17 61.7 0.0 7.9e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.6 AMK76837.1 - 0.00012 22.5 0.1 0.00016 22.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AMK76837.1 - 0.0017 18.2 0.1 0.0026 17.5 0.0 1.4 1 1 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 AMK76837.1 - 0.003 17.5 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 AMK76837.1 - 0.0068 16.3 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 AMK76837.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 AMK76837.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 AMK76837.1 - 0.029 14.6 0.0 0.13 12.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 AMK76837.1 - 0.051 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 AMK76837.1 - 0.054 12.7 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Microtub_bd PF16796.5 AMK76837.1 - 0.065 13.2 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Microtubule binding RsgA_GTPase PF03193.16 AMK76837.1 - 0.08 12.8 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DUF2791 PF10923.8 AMK76837.1 - 0.088 11.6 0.0 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) AAA_24 PF13479.6 AMK76837.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AMK76837.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AMK76837.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AMK76837.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AMK76837.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 AMK76837.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Kinesin PF00225.23 AMK76837.1 - 0.29 10.0 0.0 0.38 9.6 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain DUF2069 PF09842.9 AMK76838.1 - 1.4e-26 92.7 6.0 1.6e-26 92.5 6.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2069) YceI PF04264.13 AMK76839.1 - 7.3e-36 123.9 0.0 8.4e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 YceI-like domain Acetyltransf_1 PF00583.25 AMK76840.1 - 4.2e-20 72.1 0.0 4.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AMK76840.1 - 2.3e-12 47.1 0.0 3.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AMK76840.1 - 6e-12 45.6 0.0 7.6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AMK76840.1 - 7.9e-08 32.4 0.0 9.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AMK76840.1 - 6.6e-05 23.6 0.0 8.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 AMK76840.1 - 7.4e-05 22.5 0.1 9.5e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_6 PF13480.7 AMK76840.1 - 9.2e-05 22.6 0.1 0.00012 22.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AMK76840.1 - 0.0021 18.0 0.1 0.0033 17.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 AMK76840.1 - 0.004 16.9 0.0 0.016 14.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK76840.1 - 0.0077 16.3 0.0 0.021 15.0 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 AMK76840.1 - 0.014 16.1 0.0 1.5 9.5 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AMK76840.1 - 0.025 14.7 0.0 0.026 14.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_2e PF02091.15 AMK76841.1 - 4.1e-153 508.5 0.0 4.6e-153 508.3 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit tRNA_synt_2f PF02092.17 AMK76842.1 - 3.3e-203 676.5 0.0 7.6e-203 675.3 0.0 1.5 2 0 0 2 2 2 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 AMK76842.1 - 1.5e-06 28.4 1.5 3.6e-06 27.1 1.5 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain HD PF01966.22 AMK76842.1 - 0.008 16.4 0.5 0.022 15.0 0.5 1.8 1 0 0 1 1 1 1 HD domain CENP-F_C_Rb_bdg PF10490.9 AMK76842.1 - 0.066 12.6 0.2 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Vps54_N PF10475.9 AMK76842.1 - 0.14 11.4 0.1 0.31 10.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Hydrolase_like PF13242.6 AMK76843.1 - 1.3e-13 50.8 0.0 2.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PNK3P PF08645.11 AMK76843.1 - 1.9e-07 30.9 0.0 2.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 AMK76843.1 - 1.8e-05 24.9 0.1 0.0027 17.8 0.0 2.4 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK76843.1 - 5.5e-05 23.5 0.0 0.00012 22.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK76843.1 - 0.0006 20.3 0.2 0.0012 19.3 0.1 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AMK76843.1 - 0.0052 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF1485 PF07364.12 AMK76843.1 - 0.099 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase family M81 Acyltransferase PF01553.21 AMK76844.1 - 5.4e-19 68.2 0.0 7.2e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF393 PF04134.12 AMK76845.1 - 5.8e-14 53.4 1.6 1.5e-13 52.1 1.6 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF393 VKG_Carbox PF05090.14 AMK76845.1 - 0.00013 21.0 25.2 0.0002 20.4 25.2 1.3 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase DUF2721 PF11026.8 AMK76846.1 - 0.22 11.4 3.9 9.5 6.1 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2970 PF11174.8 AMK76847.1 - 1.6e-20 72.7 5.0 1.8e-20 72.6 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) DUF4389 PF14333.6 AMK76847.1 - 0.66 9.9 6.8 0.3 11.0 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Met_synt_B12 PF02965.17 AMK76848.1 - 1.7e-131 437.7 0.0 3e-131 436.9 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 AMK76848.1 - 1.1e-77 261.4 0.0 2.7e-77 260.2 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 AMK76848.1 - 5.8e-63 212.8 2.2 2.1e-62 211.0 0.8 2.5 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.17 AMK76848.1 - 2.2e-24 85.7 1.9 4e-24 84.8 0.3 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 AMK76848.1 - 6.2e-21 74.7 0.3 1.9e-20 73.1 0.3 1.9 1 0 0 1 1 1 1 B12 binding domain DUF836 PF05768.14 AMK76849.1 - 1.6e-13 50.8 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 AMK76849.1 - 0.0025 18.0 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin YjfB_motility PF14070.6 AMK76850.1 - 2.3e-10 40.5 6.6 2.6e-10 40.3 6.6 1.1 1 0 0 1 1 1 1 Putative motility protein rve PF00665.26 AMK76851.1 - 2.3e-25 89.1 0.0 4.6e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK76851.1 - 5.5e-21 74.1 0.3 1.3e-20 72.9 0.3 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AMK76851.1 - 4.1e-07 30.0 0.5 7.6e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 HTH-like domain Rhomboid_SP PF12595.8 AMK76851.1 - 0.024 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Rhomboid serine protease Glyco_trans_1_3 PF13528.6 AMK76853.1 - 2.4e-07 30.3 0.0 0.0043 16.3 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 1 Glyco_trans_4_4 PF13579.6 AMK76853.1 - 0.00093 19.7 2.2 0.0076 16.7 1.3 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_tran_28_C PF04101.16 AMK76853.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 AMK76853.1 - 0.0033 17.4 0.1 0.35 10.8 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 UDPGT PF00201.18 AMK76853.1 - 0.01 14.7 0.0 0.072 11.9 0.0 1.9 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase HemolysinCabind PF00353.19 AMK76855.1 - 2.5e-133 433.1 568.8 3.3e-09 36.6 9.3 38.1 28 12 11 40 40 40 34 RTX calcium-binding nonapeptide repeat (4 copies) HCBP_related PF06594.11 AMK76855.1 - 8.7e-28 96.0 20.7 1.3e-05 25.0 0.0 10.1 9 0 0 9 9 9 8 Haemolysin-type calcium binding protein related domain CBM60 PF16841.5 AMK76855.1 - 1e-25 90.0 8.0 8.1e-14 51.8 0.5 3.8 3 0 0 3 3 3 2 Ca-dependent carbohydrate-binding module xylan-binding He_PIG PF05345.12 AMK76855.1 - 0.0036 17.5 1.6 0.0036 17.5 1.6 3.8 3 0 0 3 3 3 1 Putative Ig domain ABC_membrane PF00664.23 AMK76856.1 - 6.3e-57 193.3 9.0 8.6e-57 192.9 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AMK76856.1 - 1.3e-34 119.7 0.0 2.1e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Peptidase_C39 PF03412.15 AMK76856.1 - 1.9e-24 86.0 0.0 3.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family SMC_N PF02463.19 AMK76856.1 - 7e-07 28.9 0.0 7.2e-05 22.3 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AMK76856.1 - 0.00031 21.1 0.1 0.0007 20.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AMK76856.1 - 0.0024 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AMK76856.1 - 0.015 15.1 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AMK76856.1 - 0.016 15.5 0.1 0.067 13.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 AMK76856.1 - 0.017 15.3 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 AMK76856.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 AMK76856.1 - 0.024 13.6 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 AMK76856.1 - 0.038 12.8 0.3 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 AMK76856.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AMK76856.1 - 0.08 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 AMK76856.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 AMK76856.1 - 0.16 12.1 0.1 0.39 10.8 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 AMK76856.1 - 0.23 10.6 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit HlyD_3 PF13437.6 AMK76857.1 - 3e-19 69.7 2.4 7.3e-17 62.0 0.8 2.9 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 AMK76857.1 - 1.3e-12 47.4 10.5 4.4e-11 42.4 1.2 2.7 2 1 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 AMK76857.1 - 2.2e-09 37.1 0.3 5.3e-09 35.8 0.3 1.6 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 AMK76857.1 - 6.6e-08 32.3 9.0 1.6e-07 31.0 0.3 3.8 4 0 0 4 4 4 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76857.1 - 0.00067 19.4 0.4 0.046 13.5 0.0 2.9 2 1 0 2 2 2 1 Biotin-requiring enzyme TMF_TATA_bd PF12325.8 AMK76857.1 - 0.0045 17.2 3.3 0.0045 17.2 3.3 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding PapD-like PF14874.6 AMK76857.1 - 0.044 13.9 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Flagellar-associated PapD-like QRPTase_N PF02749.16 AMK76857.1 - 0.051 13.6 0.1 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain PTS_EIIA_1 PF00358.20 AMK76857.1 - 0.057 13.2 0.4 0.59 9.9 0.0 2.5 3 0 0 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 EELM2 PF15863.5 AMK76857.1 - 0.064 13.4 1.0 0.12 12.5 1.0 1.4 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain CSD2 PF17876.1 AMK76857.1 - 0.12 12.6 0.3 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Cold shock domain ERp29 PF07749.12 AMK76857.1 - 1.8 9.5 9.5 0.42 11.5 4.2 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain REC114-like PF15165.6 AMK76857.1 - 2 8.1 8.1 3.2 7.5 8.1 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Spc24 PF08286.11 AMK76857.1 - 4.9 7.4 9.3 2.1 8.6 2.2 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 AMK76857.1 - 9.3 5.0 17.1 14 4.5 17.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Transposase_20 PF02371.16 AMK76858.1 - 2.6e-21 75.7 0.0 4.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family rve PF00665.26 AMK76860.1 - 1.7e-06 28.2 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF772 PF05598.11 AMK76861.1 - 3.2e-22 78.3 0.7 3e-21 75.2 0.3 2.7 2 1 1 3 3 3 1 Transposase domain (DUF772) DDE_Tnp_1 PF01609.21 AMK76861.1 - 6.4e-14 52.1 0.5 1.8e-13 50.7 0.5 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK76861.1 - 5.9e-08 33.0 0.1 1.5e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 AMK76861.1 - 2.8e-05 24.4 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76861.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76862.1 - 5.3e-31 107.9 2.9 8.3e-31 107.3 2.9 1.3 1 0 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK76862.1 - 2e-17 63.0 0.0 4.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_4 PF13359.6 AMK76862.1 - 6.6e-06 25.9 0.6 1.1e-05 25.1 0.6 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 AMK76862.1 - 0.00027 21.3 0.9 0.00065 20.0 0.9 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 AMK76862.1 - 0.00094 19.4 0.2 0.0018 18.5 0.2 1.5 1 0 0 1 1 1 1 Transposase DDE domain EAL PF00563.20 AMK76864.1 - 1.6e-65 221.0 0.0 5.9e-65 219.1 0.0 2.0 2 0 0 2 2 2 1 EAL domain NMT1 PF09084.11 AMK76864.1 - 1e-50 172.7 0.2 4e-49 167.5 0.1 2.3 2 0 0 2 2 2 1 NMT1/THI5 like GGDEF PF00990.21 AMK76864.1 - 1.1e-48 165.0 0.2 5.8e-48 162.7 0.1 2.4 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain SBP_bac_3 PF00497.20 AMK76864.1 - 2.7e-48 164.4 0.0 2.4e-44 151.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 PAS_3 PF08447.12 AMK76864.1 - 9.3e-25 86.7 0.2 1.5e-14 54.1 0.0 4.0 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AMK76864.1 - 3.2e-24 85.2 0.1 2.7e-16 59.7 0.0 4.0 4 0 0 4 4 3 3 PAS domain PAS PF00989.25 AMK76864.1 - 2.2e-20 72.7 1.5 7.7e-15 54.9 0.0 3.7 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 AMK76864.1 - 1.2e-18 67.4 0.0 1.1e-08 35.3 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AMK76864.1 - 7.2e-12 45.0 0.0 1.9e-05 24.6 0.0 3.3 3 0 0 3 3 3 2 PAS domain NMT1_2 PF13379.6 AMK76864.1 - 0.00014 21.6 0.1 0.37 10.4 0.0 3.3 3 0 0 3 3 3 1 NMT1-like family Lig_chan-Glu_bd PF10613.9 AMK76864.1 - 0.025 14.8 0.0 0.064 13.4 0.0 1.8 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site TPR_14 PF13428.6 AMK76865.1 - 4.9e-05 23.8 8.5 0.14 13.1 1.3 4.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK76865.1 - 9.3e-05 23.0 0.4 9.3e-05 23.0 0.4 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 AMK76865.1 - 0.00031 20.9 3.7 0.34 11.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AMK76865.1 - 0.00037 21.0 2.7 0.00037 21.0 2.7 3.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 AMK76865.1 - 0.00086 19.3 10.0 0.014 15.6 0.4 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 AMK76865.1 - 0.034 14.5 3.0 0.5 10.7 2.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AMK76865.1 - 0.041 13.7 8.7 3.9 7.5 1.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DHNA PF04038.12 AMK76865.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.9 1 1 0 1 1 1 0 Dihydroneopterin aldolase TPR_12 PF13424.6 AMK76865.1 - 0.049 13.9 7.6 0.33 11.3 2.5 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 AMK76865.1 - 0.053 13.7 15.3 0.08 13.1 2.7 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat NFACT-R_1 PF05670.13 AMK76865.1 - 0.13 12.9 0.4 0.83 10.3 0.1 2.0 2 0 0 2 2 2 0 NFACT protein RNA binding domain ANAPC3 PF12895.7 AMK76865.1 - 0.2 11.9 3.4 0.14 12.4 0.5 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 AMK76865.1 - 2.5 8.1 7.3 0.71 9.8 0.8 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CYTH PF01928.21 AMK76866.1 - 1.8e-08 34.5 0.0 2e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 CYTH domain Imm32 PF15566.6 AMK76866.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 32 Sod_Fe_C PF02777.18 AMK76867.1 - 3e-40 136.5 0.5 1.5e-39 134.3 0.0 2.2 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AMK76867.1 - 8e-35 119.2 0.8 1.3e-34 118.5 0.8 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Peptidase_C92 PF05708.12 AMK76868.1 - 3e-13 50.2 0.0 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family GST_N_3 PF13417.6 AMK76869.1 - 1.5e-13 50.9 0.1 3.8e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK76869.1 - 4.1e-11 42.7 0.0 1.2e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 AMK76869.1 - 6.1e-09 36.1 0.1 1.6e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AMK76869.1 - 3.6e-07 30.3 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AMK76869.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AMK76869.1 - 1.7e-05 24.9 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AMK76869.1 - 0.00063 20.4 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 AMK76869.1 - 0.052 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Glutaredoxin2_C PF04399.13 AMK76869.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_C_6 PF17171.4 AMK76869.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TetR_N PF00440.23 AMK76870.1 - 3.6e-15 55.5 0.1 3.6e-15 55.5 0.1 2.2 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 AMK76870.1 - 0.00075 19.7 1.9 0.001 19.2 0.3 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DUF3387 PF11867.8 AMK76870.1 - 0.035 13.5 0.1 0.099 12.0 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3387) HTH_7 PF02796.15 AMK76870.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Polysacc_synt_C PF14667.6 AMK76871.1 - 2.7e-11 43.7 19.0 2.7e-11 43.7 19.0 4.5 2 1 3 5 5 5 2 Polysaccharide biosynthesis C-terminal domain UPF0016 PF01169.19 AMK76871.1 - 1.3 9.4 8.3 2.5 8.5 0.2 4.2 2 1 1 3 3 3 0 Uncharacterized protein family UPF0016 DUF1289 PF06945.13 AMK76872.1 - 2.7e-16 59.1 2.6 3.4e-16 58.8 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) FAD_syn PF06574.12 AMK76873.1 - 1.8e-50 170.9 0.0 4.9e-50 169.5 0.0 1.7 2 0 0 2 2 2 1 FAD synthetase Flavokinase PF01687.17 AMK76873.1 - 1.1e-36 125.5 0.1 4.8e-36 123.4 0.1 1.9 2 0 0 2 2 2 1 Riboflavin kinase CTP_transf_like PF01467.26 AMK76873.1 - 0.0014 18.8 0.2 0.004 17.4 0.1 2.0 2 1 0 2 2 2 1 Cytidylyltransferase-like DUF2835 PF11197.8 AMK76873.1 - 0.014 15.2 0.1 0.39 10.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Lysine_decarbox PF03641.14 AMK76874.1 - 4.2e-43 146.6 0.1 5.1e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AMK76874.1 - 4e-11 42.7 0.1 4.5e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AMK76874.1 - 0.17 11.1 0.3 0.27 10.5 0.3 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A LSDAT_prok PF18171.1 AMK76874.1 - 0.18 11.0 1.7 0.19 11.0 0.3 1.6 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote PilZ PF07238.14 AMK76875.1 - 6.2e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 PilZ domain Amidase PF01425.21 AMK76876.1 - 5.9e-90 302.4 0.2 1.6e-89 301.0 0.2 1.7 1 1 0 1 1 1 1 Amidase VirD1 PF07328.11 AMK76876.1 - 0.18 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 NMT1_2 PF13379.6 AMK76877.1 - 7.7e-13 48.7 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AMK76877.1 - 3.3e-12 46.8 0.0 6.6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 AMK76877.1 - 4.5e-07 29.7 0.3 9.4e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AMK76877.1 - 0.001 18.5 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NosL PF05573.12 AMK76877.1 - 0.017 15.5 0.1 0.1 12.9 0.1 2.3 1 1 0 1 1 1 0 NosL BPD_transp_1 PF00528.22 AMK76878.1 - 1.4e-14 54.3 15.3 1.4e-14 54.3 15.3 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF1072 PF06380.11 AMK76878.1 - 0.11 12.4 0.6 0.11 12.4 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1072) ABC_tran PF00005.27 AMK76879.1 - 6.8e-31 107.6 0.0 9.6e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 AMK76879.1 - 6.3e-06 26.7 0.0 2.5e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 AMK76879.1 - 1.8e-05 24.7 0.1 0.0043 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AMK76879.1 - 7.7e-05 22.7 0.1 0.00016 21.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AMK76879.1 - 0.00017 21.3 0.1 0.00058 19.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK76879.1 - 0.00033 21.1 0.0 0.00046 20.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 AMK76879.1 - 0.00036 20.8 0.5 0.007 16.6 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK76879.1 - 0.00051 20.3 0.3 0.0041 17.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AMK76879.1 - 0.0011 18.4 0.0 0.0061 16.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AMK76879.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 AMK76879.1 - 0.0071 16.3 0.1 0.02 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AMK76879.1 - 0.0075 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AMK76879.1 - 0.0097 15.4 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 AMK76879.1 - 0.012 15.6 0.3 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 AMK76879.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 AMK76879.1 - 0.02 14.5 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AMK76879.1 - 0.033 14.3 0.0 0.073 13.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 AMK76879.1 - 0.039 13.9 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AMK76879.1 - 0.04 13.7 0.3 0.13 11.9 0.1 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 AMK76879.1 - 0.044 14.3 0.0 0.064 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AMK76879.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fumarate_red_D PF02313.17 AMK76880.1 - 0.04 14.0 1.1 0.04 14.0 1.1 1.3 1 1 0 1 1 1 0 Fumarate reductase subunit D DUF5129 PF17173.4 AMK76880.1 - 0.11 11.6 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF4096 PF13340.6 AMK76881.1 - 6.7e-24 83.9 4.8 1.4e-23 82.9 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK76882.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK76882.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK76882.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK76882.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_mut PF00872.18 AMK76884.1 - 1.9e-117 392.3 0.0 2.5e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AMK76884.1 - 0.00017 21.9 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 AMK76884.1 - 0.081 12.6 0.0 9.2 5.9 0.1 2.0 1 1 1 2 2 2 0 Transposase DUF4363 PF14276.6 AMK76884.1 - 0.14 12.3 0.2 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) CHIPS PF11434.8 AMK76885.1 - 0.066 13.1 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Hemerythrin PF01814.23 AMK76888.1 - 1.9e-10 41.5 4.4 2.1e-10 41.3 4.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GSH_synth_ATP PF03917.17 AMK76889.1 - 0.05 12.4 0.2 0.054 12.3 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain DUF1508 PF07411.12 AMK76890.1 - 3.5e-09 36.4 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1508) MSV199 PF10553.9 AMK76891.1 - 0.035 14.3 0.7 0.067 13.4 0.2 1.8 2 1 0 2 2 2 0 MSV199 domain Imm19 PF15563.6 AMK76891.1 - 0.061 12.8 0.2 0.078 12.5 0.2 1.1 1 0 0 1 1 1 0 Immunity protein 19 PKD PF00801.20 AMK76892.1 - 3e-10 39.8 1.0 0.013 15.3 0.0 4.0 3 0 0 3 3 3 3 PKD domain MAM PF00629.23 AMK76892.1 - 0.097 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Adenine_deam_C PF13382.6 AMK76894.1 - 9.4e-61 204.0 0.0 1.9e-60 203.1 0.0 1.5 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 AMK76894.1 - 6.4e-30 104.6 0.0 4.4e-28 98.6 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AMK76894.1 - 0.017 14.6 0.1 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 Amidohydrolase family Transketolase_N PF00456.21 AMK76895.1 - 1.6e-15 57.0 0.3 2e-14 53.3 0.3 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 AMK76895.1 - 4.7e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 AMK76895.1 - 4.2e-06 26.5 0.0 3.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 AMK76895.1 - 0.0044 16.8 0.1 0.02 14.7 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AMK76895.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component F5_F8_type_C PF00754.25 AMK76896.1 - 4.7e-06 26.8 0.0 5.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 AMK76896.1 - 0.0022 18.0 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 XRCC1 N terminal domain NTP_transferase PF00483.23 AMK76897.1 - 1.9e-63 214.4 0.0 2.5e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AMK76897.1 - 2.1e-07 31.5 0.0 3.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 AMK76897.1 - 0.00078 18.5 0.0 0.0024 16.9 0.0 1.7 2 0 0 2 2 2 1 L-fucokinase Hexapep PF00132.24 AMK76897.1 - 0.14 12.0 1.8 3.2 7.6 0.8 2.7 2 1 1 3 3 3 0 Bacterial transferase hexapeptide (six repeats) cNMP_binding PF00027.29 AMK76898.1 - 5.5e-16 58.4 0.0 7.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TetR_C_36 PF18598.1 AMK76898.1 - 0.0019 18.1 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain SIS_2 PF13580.6 AMK76899.1 - 1.3e-33 116.0 0.2 1.6e-33 115.6 0.2 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AMK76899.1 - 0.00028 20.7 0.1 0.00058 19.7 0.1 1.5 2 0 0 2 2 2 1 SIS domain UPF0102 PF02021.17 AMK76900.1 - 2.4e-26 91.8 0.2 2.8e-26 91.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 AMK76900.1 - 0.0096 16.4 0.0 0.021 15.3 0.0 1.6 1 1 0 1 1 1 1 Nuclease-related domain NucS PF01939.16 AMK76900.1 - 0.098 12.0 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS LppC PF04348.13 AMK76901.1 - 4.4e-85 286.5 9.5 6.1e-85 286.0 9.5 1.1 1 0 0 1 1 1 1 LppC putative lipoprotein Peripla_BP_6 PF13458.6 AMK76901.1 - 1.5e-09 38.0 1.5 1.5e-09 38.0 1.5 1.7 2 0 0 2 2 2 1 Periplasmic binding protein TPR_21 PF09976.9 AMK76901.1 - 0.0018 18.0 3.0 0.0044 16.7 3.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 AMK76901.1 - 1.1 10.1 4.5 1.2e+02 3.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TP_methylase PF00590.20 AMK76902.1 - 4e-25 89.0 0.0 6e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases GIT1_C PF12205.8 AMK76902.1 - 0.022 14.9 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term HTH_Tnp_1 PF01527.20 AMK76903.1 - 9.3e-10 38.7 3.7 1.4e-09 38.1 3.7 1.2 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AMK76903.1 - 0.00051 20.1 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AMK76903.1 - 0.0026 17.7 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 AMK76903.1 - 0.0034 17.1 0.2 0.0067 16.2 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Phage_CII PF05269.11 AMK76903.1 - 0.027 14.7 0.2 0.042 14.1 0.2 1.5 1 1 0 1 1 1 0 Bacteriophage CII protein eIF3_subunit PF08597.10 AMK76903.1 - 0.052 13.5 7.5 0.055 13.4 7.5 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TPR_7 PF13176.6 AMK76903.1 - 0.055 13.5 3.8 1.4 9.1 0.1 2.9 2 2 1 3 3 3 0 Tetratricopeptide repeat NRho PF16733.5 AMK76904.1 - 0.14 12.3 0.5 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Rhomboid N-terminal domain rve PF00665.26 AMK76905.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_5 PF01022.20 AMK76905.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AMK76905.1 - 0.00036 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AMK76905.1 - 0.0021 17.8 1.8 0.015 15.1 0.0 2.7 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AMK76905.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.12 AMK76905.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AMK76905.1 - 0.019 15.0 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK76905.1 - 0.038 13.8 0.1 0.89 9.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 AMK76905.1 - 0.039 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK76905.1 - 0.042 13.9 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 AMK76905.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 AMK76905.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 AMK76905.1 - 0.12 12.5 0.0 0.81 9.9 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AMK76905.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain IstB_IS21 PF01695.17 AMK76906.1 - 4.8e-56 189.3 0.0 6.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK76906.1 - 2e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK76906.1 - 4.1e-06 26.4 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AMK76906.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AMK76906.1 - 0.0068 15.3 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK76906.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AMK76906.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AMK76906.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AMK76906.1 - 0.031 14.5 0.5 0.28 11.5 0.3 2.1 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 AMK76906.1 - 0.031 13.3 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 AMK76906.1 - 0.044 13.5 0.2 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 AMK76906.1 - 0.05 13.5 1.6 0.87 9.5 0.0 2.5 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 AMK76906.1 - 0.054 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AMK76906.1 - 0.096 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AMK76906.1 - 0.11 12.9 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 AMK76906.1 - 0.12 12.1 0.3 0.33 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK76906.1 - 0.13 12.6 2.0 0.25 11.6 1.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK76906.1 - 0.17 11.9 0.3 0.47 10.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AMK76906.1 - 0.32 11.0 1.2 0.73 9.8 0.6 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tn7_Tnp_TnsA_N PF08722.11 AMK76908.1 - 3.1e-11 43.3 0.0 6.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 TnsA endonuclease N terminal HTH_31 PF13560.6 AMK76909.1 - 2.4e-14 53.4 0.1 4.3e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AMK76909.1 - 7.9e-09 35.4 1.0 2.9e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AMK76909.1 - 1.5e-08 34.6 0.7 2.5e-08 33.8 0.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 AMK76909.1 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AMK76909.1 - 0.00027 20.8 1.7 0.0022 17.9 0.3 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AMK76909.1 - 0.00045 20.0 0.6 0.0008 19.2 0.6 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain AAA_33 PF13671.6 AMK76910.1 - 3.8e-20 72.5 0.0 4.2e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AMK76910.1 - 5.9e-06 26.8 0.0 1.6e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 AMK76910.1 - 8.7e-06 25.7 0.0 0.0064 16.4 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 AMK76910.1 - 0.02 15.3 0.0 0.028 14.8 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 AMK76910.1 - 0.044 14.2 0.0 0.44 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 AMK76910.1 - 0.05 13.0 0.0 0.064 12.7 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 AMK76910.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AMK76910.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 AMK76910.1 - 0.075 12.9 0.0 0.43 10.5 0.0 2.0 1 1 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 AMK76910.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase MMR_HSR1 PF01926.23 AMK76910.1 - 0.12 12.5 0.1 0.35 11.0 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SKI PF01202.22 AMK76910.1 - 0.18 11.9 0.1 1.2 9.2 0.1 2.0 1 1 0 1 1 1 0 Shikimate kinase AAA_25 PF13481.6 AMK76910.1 - 0.19 11.3 0.8 3.7 7.1 0.3 2.1 2 0 0 2 2 2 0 AAA domain DUF4440 PF14534.6 AMK76911.1 - 3.4e-08 33.8 0.0 3.9e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AMK76911.1 - 2.5e-07 31.0 0.1 3e-07 30.7 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AMK76911.1 - 2.6e-06 28.0 0.1 3.4e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AMK76911.1 - 0.0094 16.1 0.1 0.023 14.8 0.1 1.6 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain NTF2 PF02136.20 AMK76911.1 - 0.016 15.7 0.0 0.021 15.4 0.0 1.3 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF2150 PF09920.9 AMK76911.1 - 0.15 12.0 0.7 0.51 10.3 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) DUF4336 PF14234.6 AMK76912.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) CPBP PF02517.16 AMK76912.1 - 7.8 6.9 17.3 0.13 12.7 0.7 2.6 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease PspB PF06667.12 AMK76912.1 - 9.6 6.3 7.3 41 4.3 1.5 3.4 3 0 0 3 3 3 0 Phage shock protein B HTH_17 PF12728.7 AMK76915.1 - 6.7e-12 45.4 1.1 0.00029 21.0 0.0 4.1 4 0 0 4 4 4 3 Helix-turn-helix domain MerR PF00376.23 AMK76915.1 - 5.7e-06 26.0 0.0 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 MerR family regulatory protein TniQ PF06527.11 AMK76915.1 - 5.8e-06 27.1 3.6 9e-06 26.4 1.4 2.4 3 0 0 3 3 3 1 TniQ HTH_28 PF13518.6 AMK76915.1 - 0.00038 20.5 0.1 2.5 8.3 0.0 3.5 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_3 PF01381.22 AMK76915.1 - 0.00082 19.4 0.1 0.55 10.3 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix MerR_1 PF13411.6 AMK76915.1 - 0.00089 19.3 0.0 0.27 11.3 0.0 3.1 2 1 0 2 2 2 1 MerR HTH family regulatory protein Sigma70_r4 PF04545.16 AMK76915.1 - 0.001 18.5 0.1 4.2 7.0 0.0 4.3 4 1 1 5 5 5 1 Sigma-70, region 4 HTH_24 PF13412.6 AMK76915.1 - 0.0014 18.2 0.1 0.35 10.4 0.0 3.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AMK76915.1 - 0.0045 17.0 0.0 2.2 8.3 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn helix AbiEi_4 PF13338.6 AMK76915.1 - 0.013 15.7 0.1 1.2 9.3 0.0 2.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_23 PF13384.6 AMK76915.1 - 0.027 14.3 0.1 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 AMK76915.1 - 0.067 13.0 0.3 0.32 10.8 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain HAT PF02184.16 AMK76915.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat MarR_2 PF12802.7 AMK76915.1 - 0.14 12.0 1.2 20 5.2 0.1 3.6 3 1 0 3 3 3 0 MarR family TniB PF05621.11 AMK76916.1 - 6.8e-29 100.6 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AMK76916.1 - 3.6e-18 66.2 0.0 6e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 AMK76916.1 - 0.00041 19.7 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 AMK76916.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 AMK76916.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AMK76916.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 AMK76916.1 - 0.0087 16.5 0.2 0.037 14.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AMK76916.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK76916.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 AMK76916.1 - 0.019 15.5 0.0 0.064 13.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF87 PF01935.17 AMK76916.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AMK76916.1 - 0.098 12.0 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 AMK76916.1 - 0.17 11.8 0.1 0.63 9.9 0.1 2.0 1 1 1 2 2 2 0 RsgA GTPase G-alpha PF00503.20 AMK76916.1 - 0.17 11.0 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit rve PF00665.26 AMK76917.1 - 6e-16 58.7 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AMK76917.1 - 6.9e-10 38.7 0.0 2.3e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Mu transposase, C-terminal Tn7_Tnp_TnsA_N PF08722.11 AMK76918.1 - 7.3e-11 42.1 0.1 1.8e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 TnsA endonuclease N terminal PDDEXK_10 PF07788.11 AMK76918.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily HTH_31 PF13560.6 AMK76919.1 - 7.1e-10 39.1 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AMK76919.1 - 1.6e-06 28.1 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AMK76919.1 - 2.8e-06 27.3 0.0 8.4e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Mrr_N PF14338.6 AMK76919.1 - 0.00087 19.4 0.3 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Mrr N-terminal domain IZUMO PF15005.6 AMK76919.1 - 0.049 14.1 0.1 0.056 13.9 0.1 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated HTH_37 PF13744.6 AMK76919.1 - 0.088 12.8 0.4 1.9 8.5 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain HEPN_Toprim_N PF18871.1 AMK76920.1 - 1.2e-75 254.2 0.1 1.6e-75 253.8 0.1 1.2 1 0 0 1 1 1 1 HEPN/Toprim N-terminal domain 1 Toprim_2 PF13155.6 AMK76920.1 - 0.023 15.1 0.0 0.074 13.5 0.0 1.8 2 0 0 2 2 2 0 Toprim-like Toprim_4 PF13662.6 AMK76920.1 - 0.19 12.3 0.1 0.85 10.1 0.0 2.1 2 0 0 2 2 2 0 Toprim domain DDE_Tnp_1 PF01609.21 AMK76921.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK76921.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK76921.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK76921.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK76921.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK76921.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK76921.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK76921.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK76921.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK76921.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK76921.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK76921.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK76921.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain Baculo_19 PF04798.12 AMK76922.1 - 0.033 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region KxDL PF10241.9 AMK76922.1 - 0.046 14.0 0.1 0.19 12.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein Avidin PF01382.17 AMK76923.1 - 1.4e-24 86.8 1.8 1.6e-24 86.6 1.8 1.1 1 0 0 1 1 1 1 Avidin family MVL PF12151.8 AMK76923.1 - 1.2 9.1 4.9 13 5.7 0.8 2.6 3 0 0 3 3 3 0 Mannan-binding protein DNA_methylase PF00145.17 AMK76924.1 - 3.3e-32 112.2 0.0 2.6e-30 105.9 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Vsr PF03852.15 AMK76925.1 - 4.9e-29 100.0 0.2 1e-28 99.0 0.1 1.6 2 0 0 2 2 2 1 DNA mismatch endonuclease Vsr DUF559 PF04480.12 AMK76925.1 - 4.4e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 AMK76925.1 - 5.2e-05 23.4 0.1 0.00042 20.4 0.2 2.0 1 1 1 2 2 2 1 REase_MTES_1575 HATPase_c_3 PF13589.6 AMK76927.1 - 8.6e-23 80.7 0.0 1.3e-20 73.6 0.1 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AMK76927.1 - 1.6e-14 54.3 0.1 1.7e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK76927.1 - 4.1e-06 26.7 0.0 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AMK76927.1 - 2.2e-05 24.3 0.0 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 GHKL domain RestrictionMunI PF11407.8 AMK76927.1 - 0.029 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II restriction enzyme MunI MerC PF03203.14 AMK76928.1 - 0.11 13.0 4.1 0.13 12.7 2.8 1.6 1 1 1 2 2 2 0 MerC mercury resistance protein TniQ PF06527.11 AMK76930.1 - 2e-09 38.3 11.8 4e-09 37.3 5.3 3.9 4 1 0 4 4 4 1 TniQ HTH_psq PF05225.16 AMK76930.1 - 0.0044 16.7 0.0 0.35 10.6 0.0 3.2 4 0 0 4 4 4 1 helix-turn-helix, Psq domain ALGX PF16822.5 AMK76930.1 - 0.0076 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX HTH_17 PF12728.7 AMK76930.1 - 0.025 14.8 0.0 0.69 10.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain FH2 PF02181.23 AMK76930.1 - 0.029 13.5 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Formin Homology 2 Domain UPF0175 PF03683.13 AMK76930.1 - 0.047 13.4 0.4 2 8.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) zinc-ribbons_6 PF07191.12 AMK76930.1 - 0.13 12.3 1.4 0.3 11.1 1.4 1.6 1 0 0 1 1 1 0 zinc-ribbons PCI PF01399.27 AMK76930.1 - 0.3 11.6 2.1 64 4.1 0.0 4.0 4 1 0 4 4 4 0 PCI domain TniB PF05621.11 AMK76931.1 - 5.7e-28 97.6 0.0 8.7e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 AMK76931.1 - 3.3e-17 63.0 0.0 5.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AMK76931.1 - 8.5e-07 29.5 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AMK76931.1 - 2.2e-06 27.7 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 AMK76931.1 - 7e-06 26.1 0.0 2.9e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK76931.1 - 6.1e-05 23.5 0.0 0.00042 20.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 AMK76931.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK76931.1 - 0.0011 19.5 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AMK76931.1 - 0.0011 18.6 0.0 0.0059 16.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF2075 PF09848.9 AMK76931.1 - 0.0031 16.8 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 AMK76931.1 - 0.0047 16.5 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 AMK76931.1 - 0.0073 15.9 0.2 2.4 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AMK76931.1 - 0.0075 16.4 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AMK76931.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 AMK76931.1 - 0.025 14.9 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AMK76931.1 - 0.025 14.6 0.1 0.063 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 AMK76931.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 AMK76931.1 - 0.06 13.9 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AMK76931.1 - 0.062 13.0 0.0 0.09 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 AMK76931.1 - 0.095 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase MobB PF03205.14 AMK76931.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 AMK76931.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.5 2 0 0 2 2 2 0 Rad17 P-loop domain rve PF00665.26 AMK76932.1 - 2.5e-15 56.7 0.0 5.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AMK76932.1 - 4.7e-12 45.7 0.0 2.1e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Mu transposase, C-terminal HTH_Tnp_Mu_2 PF09039.11 AMK76932.1 - 0.011 15.8 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain ParBc_2 PF08857.11 AMK76932.1 - 0.029 14.4 0.5 1.5 8.9 0.2 2.4 2 0 0 2 2 2 0 Putative ParB-like nuclease Tn7_Tnp_TnsA_N PF08722.11 AMK76933.1 - 2.5e-11 43.6 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 TnsA endonuclease N terminal HTH_31 PF13560.6 AMK76934.1 - 5.1e-14 52.4 0.2 1.1e-13 51.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AMK76934.1 - 3.1e-09 36.7 1.9 5.8e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 AMK76934.1 - 1.6e-08 34.5 0.9 1.6e-08 34.5 0.9 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 AMK76934.1 - 9.2e-05 22.8 0.1 0.00019 21.8 0.0 1.5 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AMK76934.1 - 0.00045 20.0 0.4 0.0008 19.2 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AMK76934.1 - 0.00076 19.4 0.8 0.0029 17.5 0.2 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain AAA_33 PF13671.6 AMK76935.1 - 1e-19 71.1 0.0 1.2e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 AMK76935.1 - 7.7e-06 25.9 0.0 0.0071 16.2 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 AMK76935.1 - 8.9e-06 26.3 0.0 3.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK76935.1 - 0.01 16.2 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 AMK76935.1 - 0.046 14.1 0.0 0.64 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AMK76935.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AMK76935.1 - 0.069 12.4 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.20 AMK76935.1 - 0.076 12.9 0.0 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.10 AMK76935.1 - 0.084 12.3 0.0 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.20 AMK76935.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase SKI PF01202.22 AMK76935.1 - 0.13 12.4 0.0 0.52 10.4 0.0 1.8 1 1 0 1 1 1 0 Shikimate kinase MMR_HSR1 PF01926.23 AMK76935.1 - 0.13 12.4 0.1 0.36 10.9 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 AMK76935.1 - 0.24 11.0 0.8 3.7 7.1 0.3 2.1 2 0 0 2 2 2 0 AAA domain DUF4440 PF14534.6 AMK76936.1 - 5e-08 33.3 0.0 5.7e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 AMK76936.1 - 1.2e-07 32.0 0.1 1.5e-07 31.7 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 AMK76936.1 - 2.4e-06 28.1 0.1 3.2e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AMK76936.1 - 0.0088 16.2 0.1 0.021 14.9 0.1 1.5 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain NTF2 PF02136.20 AMK76936.1 - 0.013 16.1 0.0 0.016 15.8 0.0 1.3 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF2150 PF09920.9 AMK76936.1 - 0.13 12.2 0.8 0.37 10.8 0.2 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) TauE PF01925.19 AMK76937.1 - 2.3e-30 106.0 35.2 2.3e-30 106.0 35.2 1.4 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE TauE PF01925.19 AMK76938.1 - 3.5e-50 170.8 27.2 4.4e-50 170.5 27.2 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE OAD_gamma PF04277.13 AMK76939.1 - 0.018 15.6 0.0 0.018 15.6 0.0 1.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CAT PF00302.18 AMK76939.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase cobW PF02492.19 AMK76940.1 - 3.1e-40 137.6 0.0 4.4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain PAD PF03068.15 AMK76940.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) MerC PF03203.14 AMK76942.1 - 4.9e-07 30.2 11.8 6.8e-07 29.8 11.8 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein DUF3572 PF12096.8 AMK76942.1 - 0.0066 16.6 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3572) DUF3318 PF11780.8 AMK76942.1 - 0.021 14.8 0.3 0.15 12.0 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3318) AFOR_N PF02730.15 AMK76942.1 - 0.027 14.3 0.2 0.047 13.5 0.0 1.4 2 0 0 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain TraL PF07178.11 AMK76942.1 - 3.3 8.2 6.0 0.53 10.8 0.5 2.1 1 1 1 2 2 2 0 TraL protein DUF2244 PF10003.9 AMK76942.1 - 7.3 6.3 11.8 0.13 12.0 0.8 2.2 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) MerT PF02411.15 AMK76942.1 - 7.8 6.6 10.1 9.4 6.3 8.8 1.9 1 1 1 2 2 2 0 MerT mercuric transport protein MerR_1 PF13411.6 AMK76943.1 - 4e-11 42.8 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AMK76943.1 - 9.7e-07 29.2 0.4 2.9e-06 27.7 0.3 1.9 2 1 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 AMK76943.1 - 3.3e-06 26.7 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR_2 PF13591.6 AMK76943.1 - 0.0029 17.4 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_23 PF13384.6 AMK76943.1 - 0.019 14.8 0.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain gpW PF02831.15 AMK76943.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 gpW HTH_Mga PF08280.11 AMK76943.1 - 0.051 13.6 1.0 0.071 13.1 0.1 1.7 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain AP_endonuc_2 PF01261.24 AMK76943.1 - 0.077 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Pyr_redox_2 PF07992.14 AMK76944.1 - 1.2e-64 218.4 0.5 1.7e-64 217.9 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AMK76944.1 - 1.3e-28 99.5 0.1 3.2e-28 98.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AMK76944.1 - 2e-18 66.7 1.6 9.6e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK76944.1 - 4.5e-17 62.3 0.2 2.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HMA PF00403.26 AMK76944.1 - 1.1e-08 35.4 0.0 3.5e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain FAD_oxidored PF12831.7 AMK76944.1 - 2.8e-07 30.2 6.5 6.7e-07 29.0 0.1 2.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 AMK76944.1 - 8.1e-07 28.5 5.8 2.9e-05 23.3 0.2 3.3 2 1 2 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.6 AMK76944.1 - 1.6e-06 27.5 0.0 0.0001 21.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 AMK76944.1 - 4.8e-06 26.4 3.1 0.022 14.3 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AMK76944.1 - 6.1e-06 26.6 0.2 0.038 14.4 0.0 2.9 3 0 0 3 3 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 AMK76944.1 - 1.2e-05 25.4 2.6 0.00059 20.0 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AMK76944.1 - 5.5e-05 22.1 4.7 0.05 12.3 0.8 3.0 2 1 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 AMK76944.1 - 0.00049 19.4 0.8 0.39 10.0 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 AMK76944.1 - 0.0037 17.8 1.6 0.33 11.5 0.1 3.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 AMK76944.1 - 0.0048 16.0 0.9 0.0048 16.0 0.9 3.6 3 1 0 4 4 4 1 FAD binding domain DFP PF04127.15 AMK76944.1 - 0.0056 16.5 1.2 1.9 8.3 0.1 2.5 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Thi4 PF01946.17 AMK76944.1 - 0.0092 15.2 0.1 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 AMK76944.1 - 0.016 15.1 4.9 0.94 9.3 0.1 3.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5333 PF17267.2 AMK76944.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5333) ApbA PF02558.16 AMK76944.1 - 0.33 10.6 3.5 23 4.6 0.0 3.5 3 1 1 4 4 4 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 AMK76944.1 - 0.34 10.9 3.2 4.2 7.4 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding HMA PF00403.26 AMK76945.1 - 6.4e-10 39.3 0.0 8.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2732 PF10809.8 AMK76945.1 - 0.032 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) NapD PF03927.13 AMK76945.1 - 0.04 14.0 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 NapD protein TusA PF01206.17 AMK76945.1 - 0.08 12.8 0.1 0.12 12.2 0.1 1.3 1 1 0 1 1 1 0 Sulfurtransferase TusA HMA PF00403.26 AMK76946.1 - 1.2e-14 54.5 0.1 1.7e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain TusA PF01206.17 AMK76946.1 - 0.03 14.2 0.2 0.046 13.5 0.2 1.5 1 1 0 1 1 1 0 Sulfurtransferase TusA RRM_3 PF08777.11 AMK76946.1 - 0.04 14.0 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif MerT PF02411.15 AMK76947.1 - 3e-30 104.6 2.3 3.4e-30 104.4 2.3 1.0 1 0 0 1 1 1 1 MerT mercuric transport protein DUF1772 PF08592.11 AMK76947.1 - 0.069 13.5 0.6 0.15 12.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) zf-LITAF-like PF10601.9 AMK76947.1 - 0.42 10.9 4.6 0.83 10.0 0.0 2.5 1 1 2 3 3 3 0 LITAF-like zinc ribbon domain MerC PF03203.14 AMK76947.1 - 0.9 10.0 8.3 7.1 7.1 8.3 2.0 1 1 0 1 1 1 0 MerC mercury resistance protein MerR-DNA-bind PF09278.11 AMK76948.1 - 2.8e-19 69.4 5.2 1.3e-18 67.3 4.4 2.2 2 1 0 2 2 2 1 MerR, DNA binding MerR_1 PF13411.6 AMK76948.1 - 1.7e-16 60.0 0.1 4.3e-16 58.8 0.0 1.7 1 1 1 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AMK76948.1 - 7.5e-10 38.4 0.1 1.5e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 MerR family regulatory protein DUF2316 PF10078.9 AMK76948.1 - 0.0046 17.2 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) RepB PF07506.11 AMK76948.1 - 0.006 16.7 0.1 0.0081 16.3 0.1 1.2 1 0 0 1 1 1 1 RepB plasmid partitioning protein HTH_23 PF13384.6 AMK76948.1 - 0.032 14.0 0.3 0.093 12.5 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 AMK76948.1 - 0.05 13.5 0.1 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 HTH domain CdhC PF03598.15 AMK76948.1 - 0.052 13.4 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Hexokinase_2 PF03727.16 AMK76948.1 - 0.1 12.0 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Hexokinase DNA_gyraseB PF00204.25 AMK76949.1 - 1.3e-61 207.1 0.9 2.9e-61 206.0 0.9 1.6 1 0 0 1 1 1 1 DNA gyrase B GyrB_insert PF18053.1 AMK76949.1 - 1.7e-41 141.9 0.8 3.1e-41 141.1 0.8 1.4 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain DNA_gyraseB_C PF00986.21 AMK76949.1 - 2.5e-28 98.0 0.2 7.6e-28 96.5 0.1 1.9 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AMK76949.1 - 1.4e-19 70.6 0.1 4.4e-19 69.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AMK76949.1 - 1.9e-18 66.6 0.0 8e-18 64.6 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 AMK76949.1 - 0.00054 19.8 0.1 0.0013 18.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_N PF02463.19 AMK76950.1 - 2.5e-25 89.2 0.0 3.3e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK76950.1 - 2e-08 34.4 2.6 4.9e-07 29.9 2.6 2.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AMK76950.1 - 1e-07 32.0 0.0 0.00013 21.9 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AMK76950.1 - 3.7e-07 30.8 0.1 8.3e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK76950.1 - 1.1e-05 25.1 0.7 0.00013 21.6 0.0 2.5 2 1 0 2 2 2 1 P-loop containing region of AAA domain DUF2813 PF11398.8 AMK76950.1 - 6.9e-05 22.3 0.6 0.0038 16.5 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2813) AAA_27 PF13514.6 AMK76950.1 - 0.00032 20.4 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK76950.1 - 0.0004 20.8 0.1 0.017 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 AMK76950.1 - 0.00076 20.0 0.7 0.025 15.1 0.7 2.3 1 1 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 AMK76950.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DNA_pol3_beta PF00712.19 AMK76951.1 - 2.8e-46 156.6 1.1 1.7e-39 134.7 0.1 3.1 3 0 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 AMK76951.1 - 6.1e-41 139.3 0.1 6.8e-31 106.9 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 AMK76951.1 - 1.8e-29 102.0 1.4 8.4e-27 93.4 0.1 3.4 3 1 0 4 4 4 2 DNA polymerase III beta subunit, C-terminal domain Bac_DnaA PF00308.18 AMK76952.1 - 3.5e-94 314.7 0.2 6.2e-94 313.9 0.2 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AMK76952.1 - 4.9e-31 106.6 0.1 1.1e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 AMK76952.1 - 1.6e-16 59.8 0.1 3.8e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 AMK76952.1 - 1e-10 41.6 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 AMK76952.1 - 4.9e-08 33.5 0.0 1.5e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AMK76952.1 - 4e-05 23.6 0.4 0.00035 20.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain Kinesin PF00225.23 AMK76952.1 - 0.00011 21.3 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.6 AMK76952.1 - 0.00029 21.1 3.7 0.43 10.8 0.2 3.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 AMK76952.1 - 0.00031 21.2 0.0 0.00099 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 AMK76952.1 - 0.00049 20.4 0.2 0.0017 18.7 0.2 2.0 1 1 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 AMK76952.1 - 0.00063 19.7 0.4 0.0042 17.0 0.4 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AMK76952.1 - 0.0039 16.9 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AMK76952.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Microtub_bd PF16796.5 AMK76952.1 - 0.023 14.7 0.8 0.065 13.2 0.1 2.1 2 1 0 2 2 2 0 Microtubule binding ATP-synt_F PF01990.17 AMK76952.1 - 0.024 15.0 0.1 2.6 8.4 0.0 3.0 3 1 0 3 3 3 0 ATP synthase (F/14-kDa) subunit PhoH PF02562.16 AMK76952.1 - 0.069 12.6 0.1 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 AMK76952.1 - 0.091 12.7 0.1 8.6 6.2 0.0 2.7 2 1 0 3 3 3 0 NTPase Guanylate_kin PF00625.21 AMK76953.1 - 3.4e-57 193.1 0.0 4e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AMK76953.1 - 8e-06 26.1 0.0 2.7e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AMK76953.1 - 0.0046 16.9 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 AMK76953.1 - 0.0047 16.5 0.1 0.57 9.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK76953.1 - 0.0066 16.9 0.0 0.009 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 AMK76953.1 - 0.0077 15.5 0.0 0.0095 15.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain MobB PF03205.14 AMK76953.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 AMK76953.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 AMK76953.1 - 0.018 15.6 0.0 0.025 15.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AMK76953.1 - 0.021 15.4 0.0 0.047 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AMK76953.1 - 0.023 15.1 0.0 0.051 14.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AMK76953.1 - 0.048 13.9 0.0 0.098 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AMK76953.1 - 0.076 12.3 0.2 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 AMK76953.1 - 0.079 13.3 0.1 0.088 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 AMK76953.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 AMK76953.1 - 0.16 11.8 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase ETRAMP PF09716.10 AMK76954.1 - 0.023 14.8 0.5 0.045 13.8 0.5 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Aminotran_3 PF00202.21 AMK76955.1 - 1e-75 255.0 0.0 1.2e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 AMK76955.1 - 5.3e-07 29.1 0.0 6.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Dynamin_M PF01031.20 AMK76956.1 - 4.9e-05 22.7 0.1 6.2e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Dynamin central region RNA_pol_Rpo13 PF12136.8 AMK76956.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain PhdYeFM_antitox PF02604.19 AMK76957.1 - 8.8e-18 63.9 0.1 1.1e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AMK76957.1 - 0.00016 21.7 0.1 0.00048 20.2 0.1 1.6 1 1 1 2 2 2 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system YoeB_toxin PF06769.14 AMK76958.1 - 1.4e-20 73.1 0.0 1.5e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system DUF1134 PF06577.12 AMK76959.1 - 0.0004 20.2 0.6 0.00051 19.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1134) Sperm_Ag_HE2 PF05324.13 AMK76959.1 - 0.1 13.1 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Sperm antigen HE2 RmuC PF02646.16 AMK76960.1 - 1.4e-105 352.6 3.1 1.4e-105 352.6 3.1 2.8 2 1 1 3 3 3 1 RmuC family DUF2333 PF10095.9 AMK76960.1 - 0.12 11.4 5.0 0.16 11.0 3.8 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) TPD PF14811.6 AMK76960.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function TPD sequence-motif SLATT_1 PF18181.1 AMK76960.1 - 0.57 10.1 6.1 1.2 9.1 1.8 3.1 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4854 PF16146.5 AMK76960.1 - 7.5 6.9 8.6 7.9 6.9 5.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4854) HlyD_D23 PF16576.5 AMK76962.1 - 1.9e-24 86.1 4.7 1.9e-24 86.1 4.7 1.9 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK76962.1 - 2.2e-18 66.9 4.0 1.6e-15 57.7 1.2 2.9 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK76962.1 - 8.7e-07 28.7 15.3 0.00011 21.9 1.6 3.9 4 1 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK76962.1 - 1.9e-06 27.6 0.1 0.0029 17.4 0.0 2.9 2 0 0 2 2 2 2 Biotin-requiring enzyme YqfD PF06898.11 AMK76962.1 - 0.00031 19.7 0.2 0.032 13.1 0.1 2.2 1 1 1 2 2 2 2 Putative stage IV sporulation protein YqfD PTS_EIIA_1 PF00358.20 AMK76962.1 - 0.037 13.8 0.0 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 AMK76962.1 - 0.076 12.7 0.1 4.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD PF00529.20 AMK76962.1 - 3.4 7.6 17.7 2.8 7.9 0.8 2.6 2 1 0 2 2 2 0 HlyD membrane-fusion protein of T1SS ACR_tran PF00873.19 AMK76963.1 - 5e-164 547.6 0.0 6.8e-164 547.1 0.0 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK76963.1 - 4e-07 29.3 26.4 9.1e-05 21.5 7.4 2.3 2 0 0 2 2 2 2 MMPL family Patched PF02460.18 AMK76963.1 - 0.17 10.0 11.5 0.29 9.2 11.5 1.3 1 0 0 1 1 1 0 Patched family Lipocalin_4 PF13648.6 AMK76964.1 - 0.00011 23.1 0.3 0.00015 22.7 0.3 1.2 1 0 0 1 1 1 1 Lipocalin-like domain DUF5640 PF18692.1 AMK76964.1 - 0.0081 16.2 0.8 0.016 15.2 0.8 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5640) DUF4649 PF15507.6 AMK76964.1 - 0.068 13.1 0.1 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) DUF2369 PF10179.9 AMK76964.1 - 0.14 12.6 0.0 14 6.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) GST_N_3 PF13417.6 AMK76965.1 - 2.9e-14 53.2 0.0 5.3e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK76965.1 - 1.1e-12 48.2 0.0 2.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK76965.1 - 1.4e-11 44.5 0.0 2.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK76965.1 - 0.00017 21.5 0.7 0.00029 20.8 0.6 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AMK76965.1 - 0.00045 20.9 0.0 0.00082 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 AMK76965.1 - 0.0047 17.1 0.0 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AMK76965.1 - 0.021 15.1 0.0 0.049 13.9 0.0 1.6 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GluRS_N PF18466.1 AMK76965.1 - 0.17 12.3 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain dCMP_cyt_deam_1 PF00383.23 AMK76966.1 - 3.6e-17 62.1 0.0 4.4e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AMK76966.1 - 4.1e-13 49.3 0.0 4.8e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase UbiA PF01040.18 AMK76967.1 - 1.5e-62 211.2 24.0 1.8e-62 210.9 24.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FixP_N PF14715.6 AMK76967.1 - 2.7 7.8 8.1 0.91 9.3 1.2 3.2 2 1 1 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF262 PF03235.14 AMK76968.1 - 3.8e-36 125.3 5.2 3.8e-36 125.3 5.2 2.6 2 1 0 3 3 3 1 Protein of unknown function DUF262 DUF1524 PF07510.11 AMK76968.1 - 2.6e-16 59.8 0.8 7.3e-16 58.3 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Peptidase_M99_C PF17129.4 AMK76968.1 - 0.058 13.6 3.9 0.3 11.3 0.6 2.7 2 0 0 2 2 2 0 C-terminal domain of metallo-carboxypeptidase PfkB PF00294.24 AMK76969.1 - 2.5e-46 158.3 0.2 3.4e-46 157.9 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AMK76969.1 - 9.7e-20 71.2 0.0 1.8e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 AMK76969.1 - 1.4e-10 41.0 0.0 5e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase FAD_syn PF06574.12 AMK76969.1 - 0.0052 16.7 0.1 0.1 12.5 0.0 2.8 3 0 0 3 3 3 1 FAD synthetase ArsC PF03960.15 AMK76970.1 - 1e-18 67.1 0.1 1.1e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 AMK76970.1 - 8.5e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 1 1 2 2 2 1 Glutaredoxin FMN_red PF03358.15 AMK76971.1 - 9.8e-13 48.1 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 AMK76971.1 - 1.3e-06 28.8 0.0 0.031 14.5 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_2 PF02525.17 AMK76971.1 - 1.1e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 AMK76971.1 - 0.0023 18.2 0.0 0.0098 16.1 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin Transpeptidase PF00905.22 AMK76972.1 - 1.2e-22 80.5 0.0 1.9e-22 79.9 0.0 1.3 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain Beta-lactamase2 PF13354.6 AMK76972.1 - 0.00095 18.8 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase enzyme family 3-dmu-9_3-mt PF06983.13 AMK76973.1 - 9.6e-49 164.8 0.1 1.3e-48 164.3 0.1 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase AHSA1 PF08327.11 AMK76974.1 - 2.1e-37 128.1 0.7 2.5e-37 127.9 0.7 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 AMK76974.1 - 6e-05 23.3 1.2 8.2e-05 22.9 1.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AMK76974.1 - 0.11 12.7 0.3 0.14 12.4 0.3 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AMK76975.1 - 8.5e-16 58.5 0.0 9.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 AMK76975.1 - 0.0012 19.1 0.0 0.0016 18.7 0.0 1.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF1579 PF07617.11 AMK76976.1 - 5e-62 208.4 0.2 5.6e-62 208.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1579) YCII PF03795.14 AMK76977.1 - 1.3e-25 89.7 0.1 1.4e-25 89.5 0.1 1.0 1 0 0 1 1 1 1 YCII-related domain Spt5-NGN PF03439.13 AMK76977.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section Glyoxalase PF00903.25 AMK76978.1 - 0.012 15.8 0.2 0.032 14.4 0.2 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AMK76978.1 - 0.017 15.9 0.0 0.018 15.8 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 AMK76979.1 - 2.8e-06 28.1 0.1 6.1e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.25 AMK76979.1 - 1.2e-05 25.5 0.0 2.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3-dmu-9_3-mt PF06983.13 AMK76979.1 - 0.0064 17.0 0.0 0.0089 16.6 0.0 1.3 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase YCII PF03795.14 AMK76980.1 - 8.2e-22 77.4 0.0 1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UPF0225 PF17775.1 AMK76981.1 - 2e-25 89.5 1.6 2.5e-25 89.2 1.6 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 AMK76981.1 - 2.9e-15 55.8 23.4 2.1e-09 37.1 10.4 2.2 2 0 0 2 2 2 2 SEC-C motif DUF4440 PF14534.6 AMK76981.1 - 0.0047 17.3 1.1 0.051 14.0 1.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4878 PF12870.7 AMK76981.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) CxxCxxCC PF03692.15 AMK76982.1 - 8.4e-08 32.8 1.7 5.1e-07 30.3 1.7 2.1 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Myb_DNA-binding PF00249.31 AMK76983.1 - 2.3 8.5 6.2 3.8 7.8 0.6 2.7 2 1 0 2 2 2 0 Myb-like DNA-binding domain DUF488 PF04343.13 AMK76984.1 - 7e-26 91.2 0.0 8.4e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF488 Y_phosphatase3 PF13350.6 AMK76984.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family YgbA_NO PF11756.8 AMK76984.1 - 0.11 12.9 0.6 0.14 12.5 0.6 1.2 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter TPR_7 PF13176.6 AMK76985.1 - 2.1e-08 33.6 4.3 2.8e-07 30.1 1.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Sigma70_r4_2 PF08281.12 AMK76985.1 - 2.1e-07 30.5 0.0 5.9e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK76985.1 - 3.1e-07 30.0 0.3 7.5e-07 28.8 0.3 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 TPR_2 PF07719.17 AMK76985.1 - 3.7e-06 26.6 6.8 6.8e-06 25.8 1.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 AMK76985.1 - 4.4e-06 26.5 0.1 6.9e-05 22.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AMK76985.1 - 6.6e-06 25.7 0.1 1.6e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 AMK76985.1 - 1.4e-05 24.7 0.4 8.1e-05 22.3 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AMK76985.1 - 0.00011 22.4 15.1 0.00013 22.1 1.7 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AMK76985.1 - 0.00027 21.5 11.4 0.0041 17.7 2.0 5.1 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK76985.1 - 0.00069 20.2 4.3 0.00069 20.2 4.3 5.3 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 AMK76985.1 - 0.0013 18.6 4.7 0.019 14.9 1.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 AMK76985.1 - 0.0069 17.0 5.7 0.08 13.6 0.8 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 AMK76985.1 - 0.0071 16.4 0.1 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Mak_N_cap PF18085.1 AMK76985.1 - 0.062 14.3 0.3 0.26 12.3 0.3 2.1 1 0 0 1 1 1 0 Maltokinase N-terminal cap domain TPR_21 PF09976.9 AMK76985.1 - 0.91 9.2 8.6 0.42 10.3 5.8 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 AMK76985.1 - 1 9.9 8.5 1.5 9.4 2.9 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat MarR_2 PF12802.7 AMK76986.1 - 4.3e-06 26.5 0.1 9.1e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AMK76986.1 - 2.3e-05 23.8 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AMK76986.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HxlR PF01638.17 AMK76986.1 - 0.073 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Aminotran_1_2 PF00155.21 AMK76987.1 - 7.8e-32 110.8 0.0 9.5e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AMK76987.1 - 3.1e-06 26.2 0.0 3.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF2384 PF09722.10 AMK76988.1 - 5.6e-10 39.1 0.1 9.3e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) Transgly PF00912.22 AMK76988.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Transglycosylase HTH_19 PF12844.7 AMK76988.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RES PF08808.11 AMK76989.1 - 1.9e-31 109.2 1.1 2.7e-31 108.6 1.1 1.2 1 0 0 1 1 1 1 RES domain MEKHLA PF08670.11 AMK76990.1 - 3e-53 179.6 0.0 3.4e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 MEKHLA domain PAS_8 PF13188.7 AMK76990.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 PAS domain CreA PF05981.12 AMK76991.1 - 2.6e-51 173.0 0.0 3e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 CreA protein HATPase_c PF02518.26 AMK76992.1 - 1.1e-32 112.9 0.8 2.2e-32 111.9 0.8 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK76992.1 - 2.2e-27 95.5 1.1 3.8e-27 94.7 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 AMK76992.1 - 1.4e-19 69.8 1.5 1e-18 67.1 0.0 2.9 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE8 PF17152.4 AMK76992.1 - 9.5e-14 51.5 0.7 2.5e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Periplasmic sensor domain HAMP PF00672.25 AMK76992.1 - 5.6e-10 39.4 0.1 1.5e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_5 PF14501.6 AMK76992.1 - 0.019 14.8 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 GHKL domain Rho_Binding PF08912.11 AMK76992.1 - 0.053 14.3 1.4 0.13 13.1 1.4 1.6 1 0 0 1 1 1 0 Rho Binding DUF3450 PF11932.8 AMK76992.1 - 0.11 11.7 4.6 0.23 10.8 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.14 AMK76992.1 - 2.7 8.3 9.4 4.6 7.6 6.6 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4154 PF13689.6 AMK76993.1 - 3.4e-31 108.4 0.0 4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like TonB_dep_Rec PF00593.24 AMK76994.1 - 9.4e-33 114.8 22.8 1.3e-32 114.4 22.8 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK76994.1 - 3.3e-21 75.9 0.0 6.3e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK76994.1 - 7.4e-09 35.1 14.9 4.1e-08 32.6 12.5 2.2 1 1 1 2 2 2 1 Outer membrane protein beta-barrel family Aldo_ket_red PF00248.21 AMK76995.1 - 1.3e-24 87.0 0.0 4.6e-17 62.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Response_reg PF00072.24 AMK76996.1 - 8.7e-47 157.9 0.3 4.1e-27 94.6 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AMK76996.1 - 1e-28 100.1 0.0 2e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK76996.1 - 2e-16 59.8 1.9 3.8e-16 58.9 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 AMK76996.1 - 3e-13 50.2 0.0 5.9e-12 45.9 0.0 2.5 3 0 0 3 3 3 1 Cache domain PAS_9 PF13426.7 AMK76996.1 - 1.2e-12 48.0 0.0 3.7e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AMK76996.1 - 4e-12 45.9 0.0 1.5e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK76996.1 - 9.2e-12 45.0 0.0 3.4e-11 43.2 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK76996.1 - 2.9e-09 37.2 0.1 9.7e-09 35.5 0.0 2.0 2 0 0 2 2 1 1 PAS fold Hpt PF01627.23 AMK76996.1 - 4.6e-06 26.8 0.3 4.6e-06 26.8 0.3 3.1 3 0 0 3 3 3 1 Hpt domain PAS_7 PF12860.7 AMK76996.1 - 0.0059 16.8 0.1 0.035 14.3 0.0 2.5 2 1 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AMK76996.1 - 0.0063 16.8 0.0 0.027 14.8 0.0 2.2 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AMK76996.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK76997.1 - 3.2e-24 85.3 0.0 4.9e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AMK76997.1 - 4.3e-21 75.4 0.1 8e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AMK76997.1 - 8.8e-15 54.7 0.0 5.2e-14 52.3 0.1 2.1 2 0 0 2 2 2 1 HD domain DUF1691 PF07950.11 AMK76998.1 - 0.042 14.6 0.9 0.088 13.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) ORF11CD3 PF10549.9 AMK76998.1 - 0.066 13.3 0.5 2.2 8.5 0.3 2.4 2 0 0 2 2 2 0 ORF11CD3 domain zf-ribbon_3 PF13248.6 AMK76999.1 - 0.00089 18.6 3.8 0.00089 18.6 3.8 1.7 2 0 0 2 2 2 1 zinc-ribbon domain UPF0547 PF10571.9 AMK76999.1 - 0.0009 19.3 6.8 0.0009 19.3 6.8 1.8 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 DZR PF12773.7 AMK76999.1 - 0.0014 18.6 2.1 0.0026 17.8 2.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AMK76999.1 - 0.0045 16.7 4.9 0.01 15.6 4.9 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-C2HC_2 PF13913.6 AMK76999.1 - 0.024 14.5 3.4 0.98 9.4 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 AMK76999.1 - 0.36 11.6 2.4 0.57 11.0 2.4 1.3 1 0 0 1 1 1 0 zinc-ribbon family zf_UBZ PF18439.1 AMK76999.1 - 0.46 10.1 3.1 2 8.1 0.3 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 AMK76999.1 - 1.7 9.7 3.6 4.6 8.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 AMK76999.1 - 2.6 8.1 5.7 0.53 10.3 0.3 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Acetyltransf_10 PF13673.7 AMK77000.1 - 3.2e-14 53.0 0.0 4.6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK77000.1 - 1.6e-12 47.6 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AMK77000.1 - 6.3e-11 42.6 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AMK77000.1 - 2e-05 24.7 0.1 0.00011 22.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK77000.1 - 0.0087 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 AMK77000.1 - 0.012 15.3 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 AMK77000.1 - 0.034 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 FR47-like protein NodA PF02474.15 AMK77000.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.4 1 1 0 1 1 1 0 Nodulation protein A (NodA) HATPase_c_2 PF13581.6 AMK77001.1 - 2.2e-11 43.8 0.0 3.9e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 AMK77001.1 - 0.036 14.6 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK77002.1 - 1.4e-19 70.3 0.0 1.8e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain AAA_32 PF13654.6 AMK77003.1 - 1.7e-174 581.4 0.0 2e-174 581.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 AMK77003.1 - 1.2e-12 47.9 0.1 4.3e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Mg_chelatase PF01078.21 AMK77003.1 - 0.0056 16.1 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DNA_Packaging_2 PF11123.8 AMK77003.1 - 0.012 15.8 0.8 0.18 12.0 0.1 2.7 3 0 0 3 3 3 0 DNA packaging protein DNA_pol3_beta_3 PF02768.15 AMK77003.1 - 0.047 13.5 1.0 0.13 12.1 1.0 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain DUF815 PF05673.13 AMK77003.1 - 0.13 11.4 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RmuC PF02646.16 AMK77003.1 - 0.13 11.3 2.2 1.7 7.7 0.4 2.8 3 0 0 3 3 3 0 RmuC family GTP_cyclohydro2 PF00925.20 AMK77004.1 - 5.4e-69 231.0 0.2 6.8e-69 230.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4517 PF15006.6 AMK77004.1 - 0.057 13.6 0.1 0.079 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) GIDA PF01134.22 AMK77006.1 - 1.2e-165 551.4 0.0 1.6e-165 551.0 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 AMK77006.1 - 1.6e-78 263.7 0.6 2.6e-78 263.0 0.6 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 AMK77006.1 - 1.4e-09 37.8 4.4 2.5e-09 37.0 4.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK77006.1 - 2e-07 30.4 6.1 2.3e-05 23.7 1.9 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AMK77006.1 - 2.6e-06 26.9 1.8 8e-06 25.3 1.8 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK77006.1 - 4.6e-05 23.2 2.3 0.17 11.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AMK77006.1 - 0.00061 18.6 2.0 0.0078 15.0 0.2 2.9 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 AMK77006.1 - 0.0026 17.1 0.3 0.0026 17.1 0.3 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 AMK77006.1 - 0.021 14.1 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK77006.1 - 0.042 14.4 0.4 0.13 12.8 0.4 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AMK77006.1 - 0.077 12.2 1.2 0.6 9.3 1.2 2.1 1 1 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 AMK77006.1 - 0.089 12.0 0.1 0.24 10.6 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 AMK77006.1 - 1.5 8.8 4.7 0.37 10.8 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 AMK77006.1 - 1.9 8.8 5.8 0.58 10.4 1.0 2.6 3 1 0 4 4 3 0 NAD(P)-binding Rossmann-like domain GidB PF02527.15 AMK77007.1 - 1.2e-54 184.5 0.0 1.4e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 AMK77007.1 - 2.7e-06 27.3 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AMK77007.1 - 3.9e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 AMK77007.1 - 0.0031 17.0 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 AMK77007.1 - 0.0035 18.0 0.0 0.0052 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AMK77007.1 - 0.058 13.1 0.0 0.087 12.5 0.0 1.4 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 AMK77007.1 - 0.11 13.3 0.0 0.33 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 AMK77007.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_31 PF13614.6 AMK77008.1 - 4.8e-65 218.8 0.2 6.2e-65 218.4 0.2 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK77008.1 - 2.3e-26 92.3 0.0 3.5e-26 91.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AMK77008.1 - 6.8e-15 55.2 0.0 3.6e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AMK77008.1 - 8.2e-13 48.2 0.4 1.8e-11 43.8 0.4 2.1 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 AMK77008.1 - 1.5e-11 44.3 0.7 1.6e-10 40.8 1.3 2.2 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AMK77008.1 - 3.1e-09 36.7 0.1 4.6e-07 29.6 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AMK77008.1 - 9.4e-09 34.9 0.5 4.7e-08 32.6 0.5 1.9 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 AMK77008.1 - 0.0002 20.7 0.2 0.00078 18.8 0.0 1.9 2 0 0 2 2 2 1 VirC1 protein SRP54 PF00448.22 AMK77008.1 - 0.0011 18.7 0.6 0.0059 16.3 0.2 2.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 AMK77008.1 - 0.0051 16.6 0.2 0.051 13.4 0.2 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 AMK77008.1 - 0.0075 16.1 0.2 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FTHFS PF01268.19 AMK77008.1 - 0.021 13.0 0.3 0.028 12.6 0.3 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase ParBc PF02195.18 AMK77009.1 - 1.7e-28 98.7 2.0 2.7e-28 98.1 0.5 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 AMK77009.1 - 6e-17 61.2 5.3 7.9e-17 60.8 1.2 2.6 2 0 0 2 2 2 1 HTH domain found in ParB protein HTH_23 PF13384.6 AMK77009.1 - 0.00018 21.2 0.4 0.00074 19.2 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 AMK77009.1 - 0.00037 20.4 1.3 0.0014 18.6 1.1 2.3 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_29 PF13551.6 AMK77009.1 - 0.0041 17.1 0.3 0.085 12.9 0.0 2.8 2 1 1 3 3 3 1 Winged helix-turn helix MarR_2 PF12802.7 AMK77009.1 - 0.0056 16.5 2.9 0.047 13.6 0.3 2.5 1 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 AMK77009.1 - 0.0076 15.8 0.2 0.078 12.5 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 AMK77009.1 - 0.0096 15.7 0.1 0.046 13.5 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_CodY PF08222.11 AMK77009.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain MarR PF01047.22 AMK77009.1 - 0.034 14.1 0.8 0.13 12.2 0.2 2.3 2 0 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.12 AMK77009.1 - 0.053 13.2 0.9 0.38 10.5 0.0 2.8 4 0 0 4 4 4 0 Sigma-70, region 4 TrmB PF01978.19 AMK77009.1 - 0.053 13.4 0.3 0.17 11.8 0.0 2.0 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_31 PF13560.6 AMK77009.1 - 0.13 12.6 2.1 0.59 10.5 0.4 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Img2 PF05046.14 AMK77009.1 - 0.21 11.9 0.7 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) ATP-synt_I PF03899.15 AMK77010.1 - 1.7e-16 60.4 7.3 1.7e-16 60.4 7.3 1.9 1 1 1 2 2 2 1 ATP synthase I chain DUF5518 PF17647.1 AMK77010.1 - 1.2 9.3 12.4 14 5.9 12.4 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5518) ATP-synt_A PF00119.20 AMK77011.1 - 1.7e-50 171.9 17.7 2.1e-50 171.6 17.7 1.1 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_C PF00137.21 AMK77012.1 - 5.3e-09 36.3 12.9 7.1e-09 35.9 12.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_B PF00430.18 AMK77013.1 - 3.2e-30 104.9 16.1 4.5e-30 104.4 16.1 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DivIVA PF05103.13 AMK77013.1 - 0.004 17.2 11.8 0.004 17.2 11.8 2.6 1 1 2 3 3 3 2 DivIVA protein UPF0242 PF06785.11 AMK77013.1 - 0.032 14.3 10.8 0.049 13.7 10.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HrpE PF06188.12 AMK77013.1 - 0.048 13.5 14.1 0.081 12.8 14.1 1.4 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF883 PF05957.13 AMK77013.1 - 0.17 12.5 14.8 0.071 13.7 8.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2777 PF10949.8 AMK77013.1 - 0.27 10.9 2.2 0.33 10.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) RB_A PF01858.17 AMK77013.1 - 0.4 10.5 5.1 0.5 10.2 5.1 1.1 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain DUF4746 PF15928.5 AMK77013.1 - 0.41 10.0 6.9 0.5 9.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LMBR1 PF04791.16 AMK77013.1 - 0.65 8.8 5.7 0.77 8.6 5.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V-ATPase_G_2 PF16999.5 AMK77013.1 - 1.5 9.3 27.0 2.8 8.4 26.3 1.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit FliH PF02108.16 AMK77013.1 - 1.7 8.7 11.9 0.1 12.6 3.8 2.1 1 1 1 2 2 2 0 Flagellar assembly protein FliH DUF3347 PF11827.8 AMK77013.1 - 5.3 7.2 13.7 6.3 6.9 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) OSCP PF00213.18 AMK77014.1 - 9.1e-49 165.9 1.4 1e-48 165.7 1.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_ab PF00006.25 AMK77015.1 - 4.9e-73 245.3 0.1 7.4e-73 244.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AMK77015.1 - 5.2e-46 156.1 1.1 5.2e-46 156.1 1.1 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AMK77015.1 - 5.8e-16 58.8 1.2 1.6e-15 57.4 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AMK77015.1 - 0.00012 22.2 0.6 0.0006 19.9 0.4 2.3 2 1 0 2 2 2 1 HAS barrel domain ATPase PF06745.13 AMK77015.1 - 0.00049 19.5 0.1 0.00088 18.7 0.1 1.4 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 AMK77015.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_CodY PF08222.11 AMK77015.1 - 0.12 12.0 0.1 0.35 10.4 0.1 1.9 1 0 0 1 1 1 0 CodY helix-turn-helix domain ATP-synt PF00231.19 AMK77016.1 - 6.4e-94 314.8 1.4 7.5e-94 314.6 1.4 1.0 1 0 0 1 1 1 1 ATP synthase Lentiviral_Tat PF02998.14 AMK77016.1 - 0.18 11.9 0.2 12 6.0 0.0 2.7 3 0 0 3 3 3 0 Lentiviral Tat protein ATP-synt_ab PF00006.25 AMK77017.1 - 4.1e-63 212.9 0.0 6.1e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AMK77017.1 - 6.6e-22 77.8 2.0 1.4e-21 76.7 2.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AMK77017.1 - 0.035 13.9 1.5 0.12 12.2 0.5 2.4 2 1 0 2 2 2 0 T3SS EscN ATPase C-terminal domain ATP-synt_DE_N PF02823.16 AMK77018.1 - 1e-29 102.2 0.0 1.4e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AMK77018.1 - 4.1e-11 43.0 7.5 6.8e-11 42.3 7.5 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Hexapep PF00132.24 AMK77019.1 - 5.4e-23 79.8 11.6 1.4e-08 34.1 0.2 4.5 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AMK77019.1 - 1.1e-20 74.6 0.0 1.4e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 AMK77019.1 - 3.6e-13 49.7 0.1 5.2e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 AMK77019.1 - 8.9e-09 35.0 11.9 4e-06 26.5 0.1 4.0 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 AMK77019.1 - 3.1e-08 33.7 0.5 6.7e-08 32.5 0.5 1.6 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CofC PF01983.16 AMK77019.1 - 0.00082 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Guanylyl transferase CofC like CTP_transf_3 PF02348.19 AMK77019.1 - 0.0043 17.0 0.4 0.027 14.4 0.4 2.3 1 1 0 1 1 1 1 Cytidylyltransferase Fucokinase PF07959.12 AMK77019.1 - 0.045 12.7 1.6 1.1 8.2 0.1 2.3 1 1 1 2 2 2 0 L-fucokinase GIT_CC PF16559.5 AMK77019.1 - 0.063 13.1 0.7 0.35 10.8 0.0 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4954 PF16314.5 AMK77019.1 - 0.2 9.7 2.9 0.52 8.4 2.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) SIS PF01380.22 AMK77020.1 - 1.4e-65 219.0 0.3 9.2e-35 119.4 0.1 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 AMK77020.1 - 2.8e-18 66.4 0.0 5.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AMK77020.1 - 2.3e-14 53.4 0.0 5.7e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AMK77020.1 - 1.8e-06 27.1 0.1 3.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 AMK77020.1 - 0.11 12.5 0.0 0.59 10.1 0.0 2.1 1 1 1 2 2 2 0 SIS domain Tn7_Tnp_TnsA_N PF08722.11 AMK77021.1 - 4.4e-24 84.5 0.2 1.1e-23 83.2 0.1 1.8 2 0 0 2 2 2 1 TnsA endonuclease N terminal Tn7_Tnp_TnsA_C PF08721.11 AMK77021.1 - 3e-15 56.6 0.2 2.4e-14 53.7 0.2 2.2 2 0 0 2 2 2 1 TnsA endonuclease C terminal AKAP7_RIRII_bdg PF10470.9 AMK77021.1 - 0.089 12.9 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein rve PF00665.26 AMK77022.1 - 5.3e-15 55.7 0.0 1.4e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Mu-transpos_C PF09299.11 AMK77022.1 - 0.0083 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Mu transposase, C-terminal AAA_22 PF13401.6 AMK77023.1 - 2.4e-31 108.8 0.3 2.1e-30 105.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 AMK77023.1 - 1.4e-13 50.7 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Tn7_TnsC_Int PF11426.8 AMK77023.1 - 1.5e-08 34.6 0.1 3.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Tn7 transposition regulator TnsC AAA_16 PF13191.6 AMK77023.1 - 2e-05 25.0 0.1 0.00011 22.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AMK77023.1 - 0.00025 21.5 0.0 0.00068 20.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 AMK77023.1 - 0.00049 20.1 0.0 0.0015 18.4 0.0 1.9 2 0 0 2 2 1 1 NACHT domain AAA_14 PF13173.6 AMK77023.1 - 0.0014 18.7 0.1 0.0097 15.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 AMK77023.1 - 0.0026 17.5 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AMK77023.1 - 0.0042 16.8 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AMK77023.1 - 0.0049 17.2 0.1 0.038 14.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK77023.1 - 0.013 15.2 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 AMK77023.1 - 0.018 14.4 0.0 0.06 12.7 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 AMK77023.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ATPase_2 PF01637.18 AMK77023.1 - 0.036 14.0 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 AMK77023.1 - 0.06 12.7 0.1 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 AMK77023.1 - 0.062 13.5 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 AMK77023.1 - 0.078 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.12 AMK77023.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 AMK77023.1 - 0.098 12.2 0.0 0.31 10.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 AMK77023.1 - 0.11 11.7 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 AMK77023.1 - 0.14 11.5 0.0 0.83 9.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 AMK77023.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AMK77023.1 - 0.19 11.3 0.7 1.6 8.2 0.2 2.6 2 1 0 2 2 2 0 AAA domain DnaI_N PF07319.11 AMK77024.1 - 0.058 14.1 0.1 0.08 13.6 0.1 1.5 1 1 0 1 1 1 0 Primosomal protein DnaI N-terminus TnsE_C PF18623.1 AMK77025.1 - 1.5e-50 170.9 0.0 2.7e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 TnsE C-terminal domain Excalibur PF05901.11 AMK77026.1 - 4.7e-10 39.9 0.3 1e-09 38.8 0.3 1.6 1 0 0 1 1 1 1 Excalibur calcium-binding domain CSD PF00313.22 AMK77026.1 - 1.1e-09 37.9 0.0 2.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AMK77026.1 - 0.00019 21.0 0.1 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain EAL PF00563.20 AMK77027.1 - 2e-76 256.7 0.0 3.5e-76 255.9 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK77027.1 - 1.2e-48 165.0 0.1 8.3e-48 162.2 0.0 2.2 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK77027.1 - 7.1e-26 90.5 0.1 7.6e-15 55.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK77027.1 - 3.4e-23 81.8 0.0 2.5e-14 53.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AMK77027.1 - 1.9e-14 53.3 1.3 1.9e-08 34.1 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 AMK77027.1 - 1.5e-12 47.6 0.1 1.3e-05 25.3 0.1 3.4 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AMK77027.1 - 1.8e-09 37.8 0.0 2.1e-06 27.9 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.7 AMK77027.1 - 0.0017 18.5 0.0 0.0086 16.2 0.0 2.3 1 1 0 1 1 1 1 PAS fold CheB_methylest PF01339.17 AMK77028.1 - 3.2e-52 176.7 0.0 7.1e-52 175.6 0.0 1.5 1 0 0 1 1 1 1 CheB methylesterase CheR PF01739.18 AMK77028.1 - 1.4e-50 171.5 0.0 2.6e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain PAS_10 PF13596.6 AMK77028.1 - 1.4e-32 112.4 0.3 4.6e-32 110.8 0.3 2.0 1 0 0 1 1 1 1 PAS domain CheR_N PF03705.15 AMK77028.1 - 6e-15 54.7 1.5 6e-15 54.7 1.5 2.1 2 0 0 2 2 2 1 CheR methyltransferase, all-alpha domain PAS_4 PF08448.10 AMK77028.1 - 6e-06 26.5 0.0 3.3e-05 24.1 0.0 2.3 3 0 0 3 3 1 1 PAS fold UPF0242 PF06785.11 AMK77028.1 - 0.00015 21.9 13.7 0.00039 20.6 13.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus WEMBL PF05701.11 AMK77028.1 - 0.00064 18.6 6.5 0.0011 17.8 6.5 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Golgin_A5 PF09787.9 AMK77028.1 - 0.0013 18.2 15.5 0.0025 17.4 15.5 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 AMK77028.1 - 0.0022 18.0 19.0 0.0056 16.7 19.0 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 AMK77028.1 - 0.0024 16.1 11.5 0.0037 15.5 11.5 1.2 1 0 0 1 1 1 1 HOOK protein ATG16 PF08614.11 AMK77028.1 - 0.0028 17.9 14.9 0.0065 16.7 14.9 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 AMK77028.1 - 0.003 17.2 10.5 0.0077 15.8 7.2 2.2 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 HMMR_N PF15905.5 AMK77028.1 - 0.0031 17.1 14.2 0.0056 16.2 14.2 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Rootletin PF15035.6 AMK77028.1 - 0.0033 17.5 9.0 0.0064 16.5 9.0 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion FapA PF03961.13 AMK77028.1 - 0.0035 16.0 5.3 0.0053 15.4 5.3 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Spc7 PF08317.11 AMK77028.1 - 0.0049 15.8 15.9 0.0092 14.9 15.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein ZnuA PF01297.17 AMK77028.1 - 0.0065 15.9 0.6 0.015 14.7 0.6 1.5 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic OmpH PF03938.14 AMK77028.1 - 0.0076 16.6 13.5 0.019 15.3 13.5 1.7 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Fez1 PF06818.15 AMK77028.1 - 0.0078 16.7 11.8 0.018 15.5 11.8 1.5 1 0 0 1 1 1 1 Fez1 Leu_zip PF15294.6 AMK77028.1 - 0.011 15.2 10.8 0.02 14.4 10.8 1.3 1 0 0 1 1 1 0 Leucine zipper Lebercilin PF15619.6 AMK77028.1 - 0.013 15.1 14.0 0.034 13.8 14.0 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 AMK77028.1 - 0.017 15.7 15.1 0.045 14.3 15.1 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF812 PF05667.11 AMK77028.1 - 0.019 13.9 10.0 0.028 13.3 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 AMK77028.1 - 0.02 14.9 20.7 0.053 13.6 20.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.6 AMK77028.1 - 0.024 15.1 12.9 0.079 13.4 12.9 1.9 1 0 0 1 1 1 0 Snapin/Pallidin DUF3584 PF12128.8 AMK77028.1 - 0.029 11.9 12.2 0.042 11.4 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MDM31_MDM32 PF08118.11 AMK77028.1 - 0.036 12.7 4.6 0.055 12.1 4.6 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF3450 PF11932.8 AMK77028.1 - 0.038 13.3 16.2 0.079 12.3 16.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HemX PF04375.14 AMK77028.1 - 0.041 13.2 10.0 0.077 12.3 10.0 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase GAS PF13851.6 AMK77028.1 - 0.041 13.2 15.8 0.088 12.2 15.8 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 AMK77028.1 - 0.059 13.2 15.3 0.11 12.2 15.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PAS_9 PF13426.7 AMK77028.1 - 0.063 13.5 0.1 0.27 11.5 0.1 2.2 1 0 0 1 1 1 0 PAS domain Lipase PF00151.19 AMK77028.1 - 0.07 12.4 2.1 0.12 11.7 2.1 1.2 1 0 0 1 1 1 0 Lipase IFT57 PF10498.9 AMK77028.1 - 0.095 11.7 13.4 0.16 10.9 13.4 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.22 AMK77028.1 - 0.11 12.8 12.4 0.39 11.0 12.4 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 AMK77028.1 - 0.12 12.4 15.4 0.23 11.6 15.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Med30 PF11315.8 AMK77028.1 - 0.15 12.3 12.7 0.12 12.6 9.7 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 Jnk-SapK_ap_N PF09744.9 AMK77028.1 - 0.16 12.2 17.0 0.53 10.5 17.0 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 AMK77028.1 - 0.19 11.3 7.8 0.047 13.2 4.5 1.7 2 0 0 2 2 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 AMK77028.1 - 0.21 10.9 4.1 0.38 10.1 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 AMK77028.1 - 0.25 10.7 15.3 0.48 9.8 15.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HAP1_N PF04849.13 AMK77028.1 - 0.27 10.4 17.6 0.58 9.3 17.6 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 AMK77028.1 - 0.32 11.0 6.3 0.93 9.5 6.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 AMK77028.1 - 0.33 11.6 19.1 0.26 11.9 15.6 2.6 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_3 PF13758.6 AMK77028.1 - 0.4 10.8 10.0 0.85 9.7 1.2 2.7 1 1 1 2 2 2 0 Prefoldin subunit AAA_23 PF13476.6 AMK77028.1 - 0.43 11.1 10.0 0.16 12.4 6.5 2.1 2 0 0 2 2 1 0 AAA domain DUF4763 PF15960.5 AMK77028.1 - 0.45 9.8 15.5 0.73 9.1 10.9 2.8 3 1 1 4 4 2 0 Domain of unknown function (DUF4763) Atg14 PF10186.9 AMK77028.1 - 0.49 9.4 9.3 1.1 8.3 9.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 AMK77028.1 - 0.55 8.1 6.1 0.88 7.4 6.1 1.2 1 0 0 1 1 1 0 Prominin TMPIT PF07851.13 AMK77028.1 - 0.67 9.2 9.4 1.2 8.4 9.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 AMK77028.1 - 0.88 9.7 18.6 1.2 9.2 14.7 2.8 3 0 0 3 3 2 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.13 AMK77028.1 - 0.9 9.1 6.7 2.2 7.8 6.7 1.7 1 0 0 1 1 1 0 fzo-like conserved region Laminin_II PF06009.12 AMK77028.1 - 0.99 9.4 10.5 3.2 7.8 10.5 1.9 1 0 0 1 1 1 0 Laminin Domain II DUF3461 PF11944.8 AMK77028.1 - 1.3 9.2 6.0 2.9 8.0 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) GrpE PF01025.19 AMK77028.1 - 1.4 8.5 11.3 3.8 7.2 11.3 1.7 1 0 0 1 1 1 0 GrpE COG2 PF06148.11 AMK77028.1 - 1.5 8.9 14.5 2 8.5 3.2 3.2 3 1 1 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.9 AMK77028.1 - 1.7 9.0 11.1 4.1 7.8 9.3 2.6 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF2203 PF09969.9 AMK77028.1 - 1.8 9.3 6.7 2 9.1 4.5 2.2 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 AMK77028.1 - 1.8 7.4 6.2 2.9 6.7 6.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein 5_nucleotid PF05761.14 AMK77028.1 - 2.1 7.2 5.6 4.2 6.2 5.6 1.5 1 0 0 1 1 1 0 5' nucleotidase family KELK PF15796.5 AMK77028.1 - 2.1 8.9 14.1 5.4 7.5 14.1 1.7 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec20 PF03908.13 AMK77028.1 - 2.9 7.9 5.7 9.5 6.2 5.7 2.0 1 0 0 1 1 1 0 Sec20 DUF16 PF01519.16 AMK77028.1 - 3.7 8.1 10.9 8.1 7.0 7.8 2.7 2 1 1 3 3 2 0 Protein of unknown function DUF16 Tho2 PF11262.8 AMK77028.1 - 4 6.6 9.4 39 3.3 7.7 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.11 AMK77028.1 - 4.2 8.0 16.1 3.3e+02 1.9 16.1 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PCRF PF03462.18 AMK77028.1 - 4.6 7.0 10.7 17 5.2 10.7 1.9 1 0 0 1 1 1 0 PCRF domain Sec8_exocyst PF04048.14 AMK77028.1 - 9.9 6.0 14.1 12 5.8 5.6 2.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Transposase_20 PF02371.16 AMK77030.1 - 9.2e-22 77.2 0.5 1.3e-21 76.7 0.1 1.4 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DUF3458_C PF17432.2 AMK77030.1 - 0.021 14.2 0.1 0.026 13.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Cnl2_NKP2 PF09447.10 AMK77030.1 - 0.09 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Cnl2/NKP2 family protein TP_methylase PF00590.20 AMK77030.1 - 0.12 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_transf_4 PF13439.6 AMK77032.1 - 9.8e-25 87.5 2.3 8.5e-24 84.5 1.4 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK77032.1 - 6.9e-23 81.9 3.2 3.5e-22 79.5 1.6 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Pentapeptide PF00805.22 AMK77032.1 - 8.1e-19 66.9 16.6 2.7e-09 36.5 2.2 3.4 1 1 2 3 3 3 3 Pentapeptide repeats (8 copies) Glycos_transf_1 PF00534.20 AMK77032.1 - 5.7e-18 65.0 0.0 3.8e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK77032.1 - 8.1e-15 55.4 0.0 1.7e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 AMK77032.1 - 3e-11 43.5 0.2 1.2e-10 41.6 0.2 2.0 1 1 0 1 1 1 1 Starch synthase catalytic domain Pentapeptide_4 PF13599.6 AMK77032.1 - 6.3e-11 42.3 0.0 1.2e-06 28.6 0.0 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 AMK77032.1 - 9.5e-08 32.1 0.0 0.01 16.0 0.0 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Glyco_trans_1_2 PF13524.6 AMK77032.1 - 2e-06 28.1 0.1 6.8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 AMK77032.1 - 0.021 14.8 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like MutS_V PF00488.21 AMK77032.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MutS domain V DUF3611 PF12263.8 AMK77032.1 - 0.11 12.3 1.2 0.71 9.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) PAS_9 PF13426.7 AMK77033.1 - 1.2e-93 308.3 0.1 1.9e-18 66.6 0.0 7.5 7 0 0 7 7 7 7 PAS domain PAS PF00989.25 AMK77033.1 - 7.1e-83 274.1 0.1 6.1e-13 48.8 0.0 7.7 7 0 0 7 7 7 7 PAS fold EAL PF00563.20 AMK77033.1 - 6.3e-72 241.9 1.8 1.1e-71 241.1 0.3 2.3 3 0 0 3 3 3 1 EAL domain PAS_4 PF08448.10 AMK77033.1 - 5.9e-64 213.2 1.0 2.8e-13 50.1 0.0 8.0 7 1 0 7 7 7 7 PAS fold GGDEF PF00990.21 AMK77033.1 - 1.3e-49 168.1 0.1 2.5e-49 167.1 0.1 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_8 PF13188.7 AMK77033.1 - 1.4e-43 146.3 0.0 2.7e-08 33.6 0.0 7.6 7 0 0 7 7 7 6 PAS domain PAS_3 PF08447.12 AMK77033.1 - 4.4e-40 135.9 0.5 4.6e-07 30.0 0.0 7.8 7 0 0 7 7 7 7 PAS fold PAS_7 PF12860.7 AMK77033.1 - 7e-15 55.2 4.8 0.00025 21.2 0.0 7.6 8 1 0 8 8 8 3 PAS fold Hemerythrin PF01814.23 AMK77033.1 - 1e-05 26.2 0.3 1e-05 26.2 0.3 2.6 3 0 0 3 3 1 1 Hemerythrin HHE cation binding domain PAS_12 PF18095.1 AMK77033.1 - 0.001 18.8 0.0 1.7 8.3 0.0 2.8 3 0 0 3 3 3 2 UPF0242 C-terminal PAS-like domain CDH PF02611.15 AMK77033.1 - 0.04 13.5 0.2 23 4.5 0.0 3.6 4 0 0 4 4 4 0 CDP-diacylglycerol pyrophosphatase GerE PF00196.19 AMK77034.1 - 2.5e-13 49.3 0.1 6.9e-13 47.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AMK77034.1 - 0.0011 18.6 0.2 0.0025 17.4 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 PAS_4 PF08448.10 AMK77034.1 - 0.063 13.5 0.0 12 6.2 0.0 2.2 2 0 0 2 2 2 0 PAS fold HTH_23 PF13384.6 AMK77034.1 - 0.76 9.6 2.6 1.7 8.5 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain Phage_integrase PF00589.22 AMK77035.1 - 1.3e-18 67.3 2.5 1.6e-18 67.1 2.5 1.1 1 0 0 1 1 1 1 Phage integrase family DUF2975 PF11188.8 AMK77037.1 - 0.14 12.0 6.3 0.65 9.9 6.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4181 PF13789.6 AMK77037.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) CitMHS PF03600.16 AMK77038.1 - 2e-50 171.7 18.2 2e-50 171.7 18.2 1.5 2 0 0 2 2 2 1 Citrate transporter CitMHS_2 PF16980.5 AMK77038.1 - 0.017 13.8 20.2 0.0035 16.1 14.8 2.4 2 2 0 2 2 2 0 Putative citrate transport MarR PF01047.22 AMK77039.1 - 1.1e-16 60.5 0.1 2.3e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AMK77039.1 - 6.5e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AMK77039.1 - 3.3e-09 37.1 0.8 4.8e-09 36.6 0.1 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 AMK77039.1 - 2.7e-07 30.7 0.1 6.9e-07 29.4 0.0 1.7 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AMK77039.1 - 2.3e-06 27.4 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 AMK77039.1 - 1.6e-05 24.8 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_24 PF13412.6 AMK77039.1 - 3.4e-05 23.3 0.0 6.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 AMK77039.1 - 0.00026 21.1 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 AMK77039.1 - 0.00032 20.7 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AMK77039.1 - 0.0004 20.1 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HxlR PF01638.17 AMK77039.1 - 0.00073 19.3 0.6 0.0018 18.1 0.0 1.9 3 0 0 3 3 3 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 AMK77039.1 - 0.00092 19.0 0.2 0.0049 16.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_36 PF13730.6 AMK77039.1 - 0.0028 17.6 0.2 0.0056 16.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 AMK77039.1 - 0.0031 17.8 0.0 0.0075 16.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AMK77039.1 - 0.0071 16.3 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Replic_Relax PF13814.6 AMK77039.1 - 0.025 14.6 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation HTH_23 PF13384.6 AMK77039.1 - 0.05 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain GntR PF00392.21 AMK77039.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family EAP30 PF04157.16 AMK77039.1 - 0.06 12.6 0.2 0.086 12.1 0.2 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family LexA_DNA_bind PF01726.16 AMK77039.1 - 0.084 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 LexA DNA binding domain B-block_TFIIIC PF04182.12 AMK77039.1 - 0.13 12.4 0.1 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_11 PF08279.12 AMK77039.1 - 0.13 12.2 0.2 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 HTH domain Glycos_transf_2 PF00535.26 AMK77040.1 - 7.1e-15 55.2 0.0 8.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 HAD PF12710.7 AMK77040.1 - 8.9e-12 45.8 0.1 1.7e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_tranf_2_3 PF13641.6 AMK77040.1 - 1.5e-06 28.3 0.2 6.9e-06 26.1 0.2 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Put_Phosphatase PF06888.12 AMK77040.1 - 7.9e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 AMK77040.1 - 0.00021 21.6 2.9 0.011 16.1 0.1 3.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK77040.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_tranf_2_4 PF13704.6 AMK77040.1 - 0.0043 17.5 0.0 0.017 15.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK77040.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF2490 PF10677.9 AMK77041.1 - 1.1e-43 149.4 1.8 1.3e-43 149.1 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) OMP_b-brl PF13505.6 AMK77041.1 - 1.8e-06 28.2 7.6 2.8e-06 27.6 7.6 1.3 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 AMK77041.1 - 0.11 12.3 1.8 0.39 10.4 0.7 2.0 2 0 0 2 2 2 0 OmpA-like transmembrane domain Voltage_CLC PF00654.20 AMK77042.1 - 4.1e-90 302.6 35.6 3e-89 299.7 31.0 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel Na_H_Exchanger PF00999.21 AMK77043.1 - 1.2e-41 142.8 49.0 1.6e-41 142.4 49.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cellulase PF00150.18 AMK77044.1 - 2.1e-32 112.7 12.2 3.3e-32 112.1 12.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 AMK77044.1 - 1.5e-05 24.6 2.8 0.0077 15.6 0.2 3.0 2 1 1 3 3 3 2 Beta-galactosidase Alpha-amylase PF00128.24 AMK77046.1 - 3.1e-39 135.5 0.1 6.1e-37 127.9 0.1 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 AMK77046.1 - 3e-06 26.6 0.0 5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 AMK77046.1 - 2.1e-05 24.6 0.0 6.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain ISPD_C PF18706.1 AMK77046.1 - 0.11 12.2 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain GGDEF PF00990.21 AMK77047.1 - 9.6e-41 139.2 0.1 1.3e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain 7TM-7TMR_HD PF07698.11 AMK77047.1 - 0.013 15.3 5.1 0.019 14.7 5.1 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase S6PP PF05116.13 AMK77048.1 - 6.6e-48 163.4 0.0 8.6e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 AMK77048.1 - 3.8e-14 53.1 0.0 4.7e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 AMK77048.1 - 0.002 17.3 0.0 0.93 8.6 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase HAD PF12710.7 AMK77048.1 - 0.0033 17.8 0.0 0.3 11.5 0.0 2.9 1 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase EB1 PF03271.17 AMK77048.1 - 0.08 13.2 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 EB1-like C-terminal motif GH-E PF14410.6 AMK77048.1 - 0.13 12.7 1.0 0.22 12.0 1.0 1.3 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues S6PP PF05116.13 AMK77049.1 - 1.2e-79 267.4 0.0 2e-79 266.6 0.0 1.4 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Glycos_transf_1 PF00534.20 AMK77049.1 - 6.8e-23 81.1 0.0 1.5e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK77049.1 - 1.6e-18 67.3 0.3 9.2e-18 64.8 0.1 2.4 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AMK77049.1 - 3.6e-15 56.6 0.1 1.3e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Hydrolase_3 PF08282.12 AMK77049.1 - 6.8e-15 55.5 0.0 1.5e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_trans_4_4 PF13579.6 AMK77049.1 - 1.3e-14 55.0 0.6 1.7e-13 51.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Sucrose_synth PF00862.19 AMK77049.1 - 6.1e-12 44.6 0.0 1.2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Sucrose synthase Glyco_trans_1_2 PF13524.6 AMK77049.1 - 5.8e-10 39.4 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 OpgC_C PF10129.9 AMK77050.1 - 3.6e-92 309.0 26.6 4.6e-92 308.7 26.6 1.1 1 0 0 1 1 1 1 OpgC protein Response_reg PF00072.24 AMK77051.1 - 2.6e-25 88.8 0.0 3.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK77051.1 - 2.6e-17 62.7 0.6 4.4e-17 61.9 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Prim-Pol PF09250.11 AMK77051.1 - 0.047 14.1 0.0 0.075 13.4 0.0 1.2 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal 2CSK_N PF08521.10 AMK77052.1 - 5.5e-38 130.2 0.2 1e-37 129.3 0.2 1.5 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal HATPase_c PF02518.26 AMK77052.1 - 1.3e-19 70.7 0.0 2.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK77052.1 - 1.4e-09 37.8 2.4 3.6e-09 36.5 2.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK77052.1 - 0.00027 21.2 0.4 0.00079 19.8 0.4 1.8 1 0 0 1 1 1 1 HAMP domain PspA_IM30 PF04012.12 AMK77052.1 - 0.022 14.3 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family HATPase_c_2 PF13581.6 AMK77052.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AMK77052.1 - 0.068 13.1 0.1 0.56 10.1 0.0 2.5 2 1 0 2 2 2 0 GHKL domain HATPase_c_3 PF13589.6 AMK77052.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HlyD_D23 PF16576.5 AMK77053.1 - 1.8e-18 66.6 0.0 3.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK77053.1 - 6.5e-15 55.7 0.0 2.1e-10 41.3 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK77053.1 - 7e-12 45.0 1.4 5.8e-09 35.6 0.1 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK77053.1 - 5.5e-09 35.7 0.5 4.3e-05 23.3 0.2 3.2 4 0 0 4 4 4 2 Biotin-requiring enzyme Catalase-rel PF06628.12 AMK77053.1 - 0.088 13.0 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Catalase-related immune-responsive APG6_N PF17675.1 AMK77053.1 - 1.7 9.2 5.4 3.2 8.3 5.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ACR_tran PF00873.19 AMK77054.1 - 0 1034.3 15.9 0 1034.1 15.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK77054.1 - 8.9e-20 70.9 9.7 5.9e-14 51.7 1.0 2.9 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 AMK77054.1 - 0.0012 18.3 12.3 0.0012 18.3 12.3 2.6 3 0 0 3 3 3 1 Protein export membrane protein MAGUK_N_PEST PF10608.9 AMK77054.1 - 0.071 13.5 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK DUF3921 PF13060.6 AMK77054.1 - 0.14 12.2 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) OEP PF02321.18 AMK77055.1 - 6.1e-52 176.2 28.1 4.7e-30 104.8 6.8 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Dak2 PF02734.17 AMK77055.1 - 0.016 15.1 0.8 0.036 14.0 0.8 1.5 1 0 0 1 1 1 0 DAK2 domain MRP-L28 PF09812.9 AMK77055.1 - 8.7 6.5 9.1 4.8 7.3 2.4 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 E1-E2_ATPase PF00122.20 AMK77056.1 - 5.4e-51 172.7 2.5 5.4e-51 172.7 2.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AMK77056.1 - 3.2e-43 147.5 9.0 3.2e-43 147.5 9.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AMK77056.1 - 4.8e-20 72.8 3.0 1.2e-18 68.2 3.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AMK77056.1 - 6.7e-18 64.1 2.0 8.9e-18 63.8 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 AMK77056.1 - 2.7e-17 62.6 0.0 5.4e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AMK77056.1 - 6e-05 22.9 1.7 0.00064 19.5 0.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK77056.1 - 0.00024 21.6 1.2 0.0077 16.6 0.2 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SPC25 PF06703.11 AMK77058.1 - 0.26 11.1 5.7 0.15 11.8 3.6 1.7 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ycf1 PF05758.12 AMK77058.1 - 0.27 9.0 3.5 0.32 8.8 3.5 1.0 1 0 0 1 1 1 0 Ycf1 SNARE_assoc PF09335.11 AMK77059.1 - 8.8e-15 55.2 3.3 1.5e-14 54.5 3.3 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF1211 PF06736.11 AMK77060.1 - 2.2e-29 101.7 3.9 2.2e-29 101.7 3.9 2.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1211) ATP-synt_A PF00119.20 AMK77060.1 - 0.22 11.4 9.8 0.8 9.6 9.8 1.8 1 1 0 1 1 1 0 ATP synthase A chain LysR_substrate PF03466.20 AMK77061.1 - 6.1e-36 123.8 0.1 8.2e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK77061.1 - 5.1e-20 71.2 0.1 9.2e-20 70.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AMK77061.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain EthD PF07110.11 AMK77062.1 - 3.6e-06 28.0 0.0 5.6e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 EthD domain DUF1330 PF07045.11 AMK77062.1 - 0.018 15.4 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) MmlI PF09448.10 AMK77062.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Esterase PF00756.20 AMK77064.1 - 0.016 14.8 0.1 0.064 12.9 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 AMK77064.1 - 0.04 13.4 0.3 0.31 10.5 0.1 2.5 3 1 1 4 4 4 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 AMK77064.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 AMK77064.1 - 0.19 11.0 0.2 4.3 6.5 0.2 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 AMK77064.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DDE_Tnp_1 PF01609.21 AMK77065.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK77065.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK77065.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK77065.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK77065.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK77065.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK77065.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK77065.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK77065.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK77065.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK77065.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK77065.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK77065.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain UPF0061 PF02696.14 AMK77066.1 - 4.5e-76 256.5 0.0 6.3e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family AAA PF00004.29 AMK77067.1 - 7.6e-14 52.3 0.0 1.4e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK77067.1 - 1.1e-05 25.4 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK77067.1 - 4.1e-05 24.0 0.1 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AMK77067.1 - 0.00087 19.6 0.0 0.074 13.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AMK77067.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AMK77067.1 - 0.0026 18.1 0.0 0.0088 16.4 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 AMK77067.1 - 0.0099 16.4 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 AMK77067.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 AMK77067.1 - 0.011 15.5 0.0 0.09 12.5 0.0 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 AMK77067.1 - 0.013 15.0 0.0 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 AMK77067.1 - 0.016 15.2 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.18 AMK77067.1 - 0.026 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein NTPase_1 PF03266.15 AMK77067.1 - 0.11 12.3 0.1 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 AMK77067.1 - 0.16 11.9 0.0 20 5.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 AMK77067.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Metallophos PF00149.28 AMK77068.1 - 7.3e-14 52.7 0.2 1.2e-13 52.0 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK77068.1 - 4.1e-09 36.8 0.0 1.1e-08 35.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 AMK77068.1 - 0.012 14.9 0.0 0.098 12.0 0.0 2.0 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily HTH_Tnp_1 PF01527.20 AMK77069.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK77069.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK77069.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK77069.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK77069.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK77069.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK77070.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK77070.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK77070.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK77070.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK77070.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK77070.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK77070.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 HemN_C PF06969.16 AMK77071.1 - 0.019 15.0 0.1 0.04 14.0 0.1 1.6 1 1 1 2 2 2 0 HemN C-terminal domain DUF1400 PF07176.11 AMK77071.1 - 0.073 13.4 0.0 0.083 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) GDPD PF03009.17 AMK77072.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Ferric_reduct PF01794.19 AMK77073.1 - 8.1e-18 64.7 5.8 8.1e-18 64.7 5.8 1.7 1 1 0 1 1 1 1 Ferric reductase like transmembrane component DUF4013 PF13197.6 AMK77073.1 - 5.5 6.8 11.8 2.5 7.9 7.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Oxidored_molyb PF00174.19 AMK77074.1 - 9e-29 100.3 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain SLBB PF10531.9 AMK77074.1 - 0.15 12.0 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 SLBB domain adh_short PF00106.25 AMK77075.1 - 8.7e-27 93.8 2.1 1.1e-26 93.5 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AMK77075.1 - 1.1e-26 93.8 2.4 1.3e-26 93.7 1.2 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AMK77075.1 - 3.2e-05 23.9 2.3 8.1e-05 22.6 2.4 1.6 1 1 0 1 1 1 1 KR domain DUF4921 PF16268.5 AMK77075.1 - 0.073 11.9 0.1 0.097 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) DUF2063 PF09836.9 AMK77076.1 - 6.5e-20 71.2 0.0 1.4e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Putative DNA-binding domain DUF692 PF05114.13 AMK77077.1 - 3.7e-104 347.6 0.0 4.2e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) DUF2974 PF11187.8 AMK77077.1 - 0.11 12.0 0.5 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lactonase PF10282.9 AMK77078.1 - 1.4e-26 93.6 0.5 3.8e-11 42.8 0.0 3.3 1 1 2 3 3 3 3 Lactonase, 7-bladed beta-propeller SGL PF08450.12 AMK77078.1 - 0.00057 19.5 0.0 0.37 10.3 0.0 3.3 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region YmzC PF14157.6 AMK77078.1 - 0.085 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 YmzC-like protein DUF3110 PF11360.8 AMK77078.1 - 0.15 12.3 0.1 0.53 10.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) DUF2282 PF10048.9 AMK77079.1 - 1e-23 83.0 2.5 1.4e-23 82.6 2.5 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2282) Sigma54_activat PF00158.26 AMK77080.1 - 4.2e-73 244.6 0.1 1.2e-72 243.1 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK77080.1 - 2.1e-19 70.0 0.0 5.1e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AMK77080.1 - 2.3e-10 40.6 0.0 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 AMK77080.1 - 6.7e-07 29.0 0.2 5.3e-06 26.1 0.1 2.5 2 1 0 2 2 2 1 Bacterial regulatory protein, Fis family PAS_4 PF08448.10 AMK77080.1 - 1.2e-06 28.7 0.0 0.00034 20.8 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 AMK77080.1 - 3.3e-06 27.3 0.0 2.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 PAS domain AAA PF00004.29 AMK77080.1 - 5.9e-06 26.7 0.1 1.8e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PAS_8 PF13188.7 AMK77080.1 - 1.4e-05 25.0 0.3 7.1e-05 22.7 0.0 2.4 3 0 0 3 3 2 1 PAS domain AAA_16 PF13191.6 AMK77080.1 - 0.00014 22.3 0.1 0.00055 20.4 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AMK77080.1 - 0.00051 19.5 0.2 0.027 13.8 0.2 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI PAS PF00989.25 AMK77080.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 2.1 1 0 0 1 1 1 1 PAS fold AAA_2 PF07724.14 AMK77080.1 - 0.0062 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 AMK77080.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein HTH_30 PF13556.6 AMK77080.1 - 0.013 15.3 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain AAA_3 PF07726.11 AMK77080.1 - 0.05 13.5 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AMK77080.1 - 0.082 12.6 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK77080.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Y1_Tnp PF01797.16 AMK77081.1 - 3.2e-05 24.0 0.1 4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Transposase IS200 like CMD PF02627.20 AMK77082.1 - 1e-12 47.9 3.4 1.4e-11 44.3 0.5 2.1 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family AAA_lid_3 PF17862.1 AMK77082.1 - 0.041 13.7 0.4 0.17 11.7 0.0 2.1 1 1 1 2 2 2 0 AAA+ lid domain Putative_PNPOx PF01243.20 AMK77083.1 - 1.5e-10 41.1 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GST_N_3 PF13417.6 AMK77084.1 - 1.5e-18 66.9 0.0 2.6e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK77084.1 - 9e-14 51.6 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK77084.1 - 2.6e-13 50.1 0.0 4.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AMK77084.1 - 1.4e-09 38.1 0.0 2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AMK77084.1 - 1.2e-05 25.2 0.3 4.4e-05 23.4 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 AMK77084.1 - 0.00044 20.4 0.0 0.00078 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 AMK77084.1 - 0.0014 19.3 0.0 0.0095 16.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 AMK77084.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LysR_substrate PF03466.20 AMK77085.1 - 4.6e-42 143.8 1.1 1.1e-41 142.5 1.0 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 AMK77085.1 - 6e-21 74.1 0.1 1.2e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF4040 PF13244.6 AMK77085.1 - 0.076 13.2 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) MarR PF01047.22 AMK77085.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MarR family PEMT PF04191.13 AMK77086.1 - 1.7e-15 57.3 1.4 1.7e-15 57.3 1.4 1.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 AMK77086.1 - 2.5e-06 27.8 0.3 4.6e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 AMK77086.1 - 0.002 17.7 1.0 0.0022 17.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Phage_holin_3_6 PF07332.11 AMK77086.1 - 0.63 10.1 12.9 0.35 10.9 6.1 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2070 PF09843.9 AMK77086.1 - 2.1 6.5 6.3 2.5 6.3 6.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4748 PF15932.5 AMK77086.1 - 8.6 6.2 7.1 4.5 7.1 0.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4748) Phage_holin_3_3 PF16083.5 AMK77087.1 - 0.48 10.6 8.2 0.25 11.5 2.9 2.6 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III VirB3 PF05101.13 AMK77087.1 - 6.6 7.0 10.4 0.82 9.9 4.3 2.4 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein FeoB_C PF07664.12 AMK77087.1 - 9.6 6.0 8.1 0.93 9.2 0.2 2.9 3 1 0 3 3 3 0 Ferrous iron transport protein B C terminus TerB PF05099.13 AMK77089.1 - 1.1e-37 129.2 0.7 1.3e-37 128.9 0.7 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TerB ClpS PF02617.17 AMK77089.1 - 0.0025 17.6 0.2 0.0037 17.0 0.2 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS HTH_50 PF18024.1 AMK77089.1 - 0.11 12.2 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain zf-HC2 PF13490.6 AMK77089.1 - 0.25 11.6 0.9 1 9.7 0.1 2.3 2 0 0 2 2 2 0 Putative zinc-finger DUF1993 PF09351.10 AMK77091.1 - 5e-64 215.3 0.1 5.6e-64 215.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) PBP PF01161.20 AMK77092.1 - 4e-40 137.2 0.0 4.7e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2956 PF11169.8 AMK77093.1 - 1.4e-40 137.6 5.8 1.6e-40 137.4 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2956) L_lactis_ph-MCP PF06673.11 AMK77093.1 - 0.4 9.6 2.2 0.52 9.2 2.2 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF2058 PF09831.9 AMK77093.1 - 0.5 10.5 10.7 0.6 10.2 10.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) FUSC-like PF12805.7 AMK77093.1 - 1.2 8.2 3.8 1.7 7.7 3.8 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DnaJ PF00226.31 AMK77094.1 - 6.5e-08 32.6 0.1 2.5e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain DUF1003 PF06210.11 AMK77094.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nitro_FeMo-Co PF02579.17 AMK77096.1 - 4e-14 52.7 0.0 5.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor Peptidase_C70 PF12385.8 AMK77098.1 - 9e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39_2 PF13529.6 AMK77098.1 - 4.8e-05 23.9 0.6 0.00012 22.7 0.6 1.6 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 AMK77098.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family H_PPase PF03030.16 AMK77102.1 - 2e-275 915.5 46.0 2.3e-275 915.3 46.0 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase TGBp3 PF02495.17 AMK77102.1 - 0.25 11.0 0.1 0.25 11.0 0.1 4.4 6 0 0 6 6 6 0 Triple gene block 3 NUDIX PF00293.28 AMK77103.1 - 5.3e-05 23.3 0.0 8.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Isochorismatase PF00857.20 AMK77104.1 - 9.8e-09 35.6 0.0 3.6e-07 30.5 0.0 2.7 1 1 0 1 1 1 1 Isochorismatase family NAPRTase PF04095.16 AMK77105.1 - 5.8e-74 248.7 0.0 7.1e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 AMK77105.1 - 1.9e-27 96.1 0.1 5.7e-27 94.6 0.1 1.9 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAD_synthase PF02540.17 AMK77106.1 - 1.8e-66 223.7 0.0 2.9e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 AMK77106.1 - 3.7e-26 92.0 0.1 1.2e-25 90.4 0.1 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_Me_trans PF03054.16 AMK77106.1 - 0.052 12.3 0.1 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.21 AMK77106.1 - 0.12 12.1 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Asparagine synthase Tic22 PF04278.12 AMK77106.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Tic22-like family NUDIX PF00293.28 AMK77107.1 - 8.9e-16 58.1 0.1 1.7e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain CTP_transf_like PF01467.26 AMK77107.1 - 8.5e-07 29.3 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 AMK77107.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-sulfurylase FAD_syn PF06574.12 AMK77107.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase QSregVF_b PF12843.7 AMK77108.1 - 4.4e-30 103.4 0.5 4.9e-30 103.2 0.5 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor Peptidase_A8 PF01252.18 AMK77109.1 - 2e-42 144.8 3.0 2.3e-42 144.6 3.0 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II ECF_trnsprt PF12822.7 AMK77109.1 - 0.018 15.1 1.8 0.024 14.8 1.8 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Amelotin PF15757.5 AMK77109.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Amelotin ThrE PF06738.12 AMK77109.1 - 1.2 8.4 5.4 6.2 6.1 0.1 1.9 1 1 1 2 2 2 0 Putative threonine/serine exporter tRNA-synt_1 PF00133.22 AMK77110.1 - 2e-217 723.3 0.0 2.3e-217 723.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AMK77110.1 - 1.6e-26 93.1 0.0 3e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AMK77110.1 - 1.8e-22 79.6 0.0 7e-11 41.5 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AMK77110.1 - 3.7e-09 36.3 0.0 6.9e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 AMK77110.1 - 3e-08 33.4 0.0 6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 AMK77110.1 - 1.2e-05 24.5 0.0 4.6e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.14 AMK77110.1 - 0.00048 19.9 5.2 0.00048 19.9 5.2 2.6 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1b PF00579.25 AMK77110.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Nitroreductase PF00881.24 AMK77111.1 - 1.1e-27 97.1 3.0 1e-25 90.8 3.0 2.2 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AMK77111.1 - 5.3e-09 36.0 0.1 2e-05 24.2 0.0 2.4 1 1 2 3 3 3 2 Putative TM nitroreductase GGDEF PF00990.21 AMK77112.1 - 7.6e-47 159.0 0.0 1.3e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AMK77112.1 - 1.1e-10 41.5 0.0 2.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK77112.1 - 1.3e-09 38.3 0.0 2.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AMK77112.1 - 1.3e-09 38.2 0.0 3.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 AMK77112.1 - 3.2e-07 30.2 0.0 1.1e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.6 AMK77112.1 - 0.00086 19.6 0.0 0.0023 18.3 0.0 1.8 1 1 0 1 1 1 1 GAF domain PAS_3 PF08447.12 AMK77112.1 - 0.073 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold Tsp45I PF06300.12 AMK77112.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme SLS PF14611.6 AMK77113.1 - 0.096 12.5 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF2721 PF11026.8 AMK77114.1 - 6.4e-34 116.6 7.1 7.6e-34 116.4 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) SecE PF00584.20 AMK77114.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.5 3 1 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex TauE PF01925.19 AMK77114.1 - 0.63 9.6 10.6 3.1 7.4 10.6 1.9 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF1129 PF06570.11 AMK77114.1 - 1.5 8.3 3.6 1.2 8.6 1.8 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Claudin_2 PF13903.6 AMK77114.1 - 2 8.1 14.3 6.3 6.5 9.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MAPEG PF01124.18 AMK77115.1 - 1.3e-23 83.3 6.5 1.5e-23 83.1 6.5 1.0 1 0 0 1 1 1 1 MAPEG family DUF998 PF06197.13 AMK77116.1 - 1e-23 83.9 17.3 1.2e-23 83.7 17.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Oxidored_q2 PF00420.24 AMK77116.1 - 0.13 11.9 3.4 0.13 11.9 2.1 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YCII PF03795.14 AMK77117.1 - 3.4e-14 53.0 0.0 4.1e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain adh_short PF00106.25 AMK77118.1 - 0.0046 16.4 0.0 0.0046 16.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 AMK77118.1 - 0.0099 15.6 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UvrD_C PF13361.6 AMK77119.1 - 1e-70 238.9 1.4 2.4e-70 237.7 0.6 2.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 AMK77119.1 - 6.4e-67 226.3 5.8 1.1e-66 225.5 1.9 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AMK77119.1 - 5.5e-32 111.1 0.1 1e-31 110.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AMK77119.1 - 1.5e-11 43.9 0.0 9.8e-10 38.1 0.0 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AMK77119.1 - 9.6e-09 35.2 0.5 3e-05 23.8 0.3 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AMK77119.1 - 1e-06 28.7 0.2 0.006 16.4 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Trypsin_2 PF13365.6 AMK77120.1 - 2.7e-32 112.8 0.8 5.1e-32 111.8 0.8 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AMK77120.1 - 3.3e-24 85.0 7.5 9.2e-16 57.9 0.2 3.8 3 1 1 4 4 4 2 PDZ domain PDZ_6 PF17820.1 AMK77120.1 - 7.5e-22 76.9 4.4 1.4e-13 50.4 0.7 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AMK77120.1 - 2.2e-18 66.4 3.3 5.9e-11 42.6 0.3 3.6 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 AMK77120.1 - 2.1e-15 57.1 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_1 PF12812.7 AMK77120.1 - 1.3e-05 25.1 0.1 0.027 14.5 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Tricorn_PDZ PF14685.6 AMK77120.1 - 0.00045 20.1 0.4 0.028 14.4 0.1 2.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain GRASP55_65 PF04495.14 AMK77120.1 - 0.014 15.7 0.0 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain DUF3394 PF11874.8 AMK77120.1 - 0.18 11.5 0.0 16 5.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) cNMP_binding PF00027.29 AMK77121.1 - 3.9e-23 81.3 0.0 3.8e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Rhodanese PF00581.20 AMK77121.1 - 3.3e-10 40.5 0.0 7.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF3450 PF11932.8 AMK77121.1 - 0.1 11.9 2.1 0.17 11.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4472 PF14739.6 AMK77121.1 - 0.12 13.1 1.8 0.23 12.2 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) PRESAN PF09687.10 AMK77121.1 - 0.12 12.9 1.1 0.27 11.8 1.1 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal APG6_N PF17675.1 AMK77121.1 - 0.14 12.6 2.4 0.27 11.7 2.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 AMK77121.1 - 0.68 10.2 4.5 1.5 9.1 1.6 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Ribosomal_L33 PF00471.20 AMK77122.1 - 7.9e-19 67.8 1.1 8.7e-19 67.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Ribosomal_L28 PF00830.19 AMK77123.1 - 3.7e-26 91.1 2.7 4.2e-26 90.9 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L28 family GSH-S_ATP PF02955.16 AMK77124.1 - 6e-78 260.2 0.0 8.1e-78 259.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 AMK77124.1 - 2.9e-46 156.4 0.0 6.2e-46 155.4 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 AMK77124.1 - 1.4e-13 50.8 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 AMK77124.1 - 7.9e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 AMK77124.1 - 0.0053 16.8 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Rimk_N PF18030.1 AMK77124.1 - 0.01 16.2 0.0 0.053 13.9 0.0 2.3 2 1 0 2 2 2 0 RimK PreATP-grasp domain ATPgrasp_ST PF14397.6 AMK77124.1 - 0.07 12.4 0.0 0.33 10.2 0.0 1.9 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp TonB_C PF03544.14 AMK77125.1 - 5.9e-12 45.8 0.8 1.8e-11 44.3 0.0 2.2 3 0 0 3 3 3 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AMK77125.1 - 4.7e-10 39.6 0.0 1.7e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 TonB C terminal DUF179 PF02622.15 AMK77126.1 - 5.5e-49 166.2 0.0 6.4e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 RuvX PF03652.15 AMK77127.1 - 5.1e-37 127.3 0.0 5.8e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase NADH_oxidored PF08040.11 AMK77127.1 - 0.13 12.0 0.0 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 MNLL subunit Pribosyltran PF00156.27 AMK77128.1 - 2.1e-17 63.1 0.0 2.6e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AMK77128.1 - 3e-05 23.5 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AMK77128.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase OTCace_N PF02729.21 AMK77129.1 - 1.9e-40 138.3 1.8 3.4e-40 137.5 1.8 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AMK77129.1 - 2.7e-27 95.8 0.0 7.3e-27 94.4 0.0 1.8 2 1 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Amidohydro_1 PF01979.20 AMK77130.1 - 1.2e-14 54.4 0.0 2.1e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AMK77130.1 - 9.3e-09 35.3 0.0 0.00026 20.6 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family DHOase PF12890.7 AMK77130.1 - 0.00014 21.8 0.1 0.00072 19.5 0.1 2.0 1 1 0 1 1 1 1 Dihydro-orotase-like Lysine_decarbox PF03641.14 AMK77131.1 - 2.3e-35 121.6 0.0 6.3e-35 120.2 0.0 1.6 2 0 0 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 AMK77131.1 - 4.2e-12 45.9 0.0 6.2e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AMK77131.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA recombination-mediator protein A AAA_3 PF07726.11 AMK77132.1 - 4.9e-63 210.8 0.1 1.3e-62 209.4 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AMK77132.1 - 7.9e-19 67.3 0.2 2.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 AMK77132.1 - 4.3e-12 46.2 0.0 7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 AMK77132.1 - 3e-08 33.1 0.0 4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AMK77132.1 - 0.00029 20.6 0.0 0.00082 19.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 AMK77132.1 - 0.0016 18.2 0.1 0.026 14.3 0.1 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 AMK77132.1 - 0.0043 16.5 0.2 2 7.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF58 PF01882.18 AMK77133.1 - 3.1e-22 78.6 0.1 7.6e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF58 PGM_PMM_I PF02878.16 AMK77133.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I EAL PF00563.20 AMK77134.1 - 2.2e-67 227.1 0.0 4.4e-67 226.1 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK77134.1 - 3.6e-47 160.1 0.0 6.9e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE PF03924.13 AMK77134.1 - 1.3e-41 142.6 0.4 3.8e-41 141.1 0.1 2.0 2 0 0 2 2 2 1 CHASE domain PAS_9 PF13426.7 AMK77134.1 - 9.7e-27 93.3 0.0 1.3e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK77134.1 - 4e-25 88.0 0.0 2.8e-16 59.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 AMK77134.1 - 2.6e-23 82.3 0.0 5.1e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold MASE1 PF05231.14 AMK77134.1 - 9.2e-22 77.5 28.8 1.7e-21 76.7 28.8 1.3 1 0 0 1 1 1 1 MASE1 PAS_3 PF08447.12 AMK77134.1 - 4.5e-15 55.7 0.0 2.9e-08 33.9 0.1 2.9 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AMK77134.1 - 1.9e-08 34.1 0.0 3.3e-06 27.0 0.0 3.0 2 0 0 2 2 2 1 PAS domain GGA_N-GAT PF18308.1 AMK77134.1 - 0.1 12.2 0.7 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 GGA N-GAT domain DUF4381 PF14316.6 AMK77135.1 - 4.3e-42 143.8 5.5 4.8e-42 143.6 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) BatD PF13584.6 AMK77135.1 - 0.19 10.5 0.2 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Oxygen tolerance VWA PF00092.28 AMK77136.1 - 2.9e-29 102.5 0.0 3.5e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 AMK77136.1 - 5.7e-18 65.5 0.1 1.1e-17 64.6 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 AMK77136.1 - 1.3e-06 27.8 0.2 0.0064 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1194) VWA_CoxE PF05762.14 AMK77136.1 - 0.11 11.8 0.6 0.79 9.1 0.6 2.1 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Copine PF07002.16 AMK77136.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Copine VWA_2 PF13519.6 AMK77137.1 - 1.8e-15 57.5 4.2 3.4e-15 56.6 0.2 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain TPR_2 PF07719.17 AMK77137.1 - 2e-11 43.0 16.6 3.9e-10 39.0 1.4 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 AMK77137.1 - 4.1e-11 42.2 1.1 4.1e-11 42.2 1.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat VWA PF00092.28 AMK77137.1 - 6.9e-11 42.7 0.8 1.3e-10 41.9 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain TPR_11 PF13414.6 AMK77137.1 - 4.2e-07 29.5 3.6 4.2e-07 29.5 3.6 4.1 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 AMK77137.1 - 4.9e-06 26.3 0.1 4.9e-06 26.3 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AMK77137.1 - 6.4e-05 23.4 0.6 6.4e-05 23.4 0.6 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 AMK77137.1 - 0.00014 22.4 7.1 0.00014 22.4 7.1 3.6 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 AMK77137.1 - 0.00017 21.6 5.0 0.00031 20.8 1.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AMK77137.1 - 0.00019 21.8 18.3 0.00038 20.9 2.0 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat VWA_CoxE PF05762.14 AMK77137.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein TPR_6 PF13174.6 AMK77137.1 - 0.0029 18.1 17.2 0.0046 17.5 0.3 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 AMK77137.1 - 0.007 16.7 10.5 0.36 11.3 0.4 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 AMK77137.1 - 0.018 14.7 0.3 0.048 13.4 0.3 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 AMK77137.1 - 0.068 13.2 7.6 0.87 9.7 2.6 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 AMK77137.1 - 0.071 13.3 7.6 0.3 11.3 6.4 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AMK77137.1 - 0.38 10.9 9.7 0.11 12.5 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AMK77137.1 - 1.5 9.1 16.6 0.13 12.6 7.4 3.3 3 1 0 3 3 2 0 Tetratricopeptide repeat DUF21 PF01595.20 AMK77138.1 - 3.9e-47 160.2 3.6 5.5e-47 159.7 3.6 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AMK77138.1 - 1.7e-19 69.6 0.1 8.1e-19 67.4 0.0 2.0 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 AMK77138.1 - 2e-10 41.0 0.1 1e-07 32.3 0.1 2.4 2 0 0 2 2 2 2 CBS domain HlyD_D23 PF16576.5 AMK77139.1 - 1.2e-65 220.7 4.0 1.6e-65 220.3 4.0 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK77139.1 - 1.7e-21 76.9 1.2 2e-17 63.8 0.5 2.7 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK77139.1 - 2.9e-07 30.2 1.1 0.00014 21.6 0.1 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD PF00529.20 AMK77139.1 - 0.0039 17.0 2.3 0.017 15.0 0.1 2.7 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AMK77139.1 - 0.045 13.6 0.9 0.48 10.3 0.0 2.7 3 0 0 3 3 3 0 Biotin-requiring enzyme SHOCT PF09851.9 AMK77139.1 - 0.048 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Short C-terminal domain GCV_H PF01597.19 AMK77139.1 - 0.12 12.3 0.1 22 5.0 0.0 2.7 2 1 1 3 3 3 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 AMK77139.1 - 0.15 12.3 0.1 29 5.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase family M23 ACR_tran PF00873.19 AMK77140.1 - 9.9e-292 970.3 22.2 1.1e-291 970.1 22.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK77140.1 - 0.0005 19.1 4.5 0.0005 19.1 4.5 2.8 2 1 0 2 2 2 1 MMPL family BatD PF13584.6 AMK77141.1 - 9.2e-110 367.7 8.6 1.1e-109 367.5 8.6 1.0 1 0 0 1 1 1 1 Oxygen tolerance NUDIX PF00293.28 AMK77142.1 - 1.1e-14 54.5 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MCPsignal PF00015.21 AMK77143.1 - 8.1e-29 100.6 38.8 6.1e-28 97.8 20.8 5.0 4 1 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 AMK77143.1 - 6.9e-27 94.1 4.8 6.9e-27 94.1 4.8 4.3 5 0 0 5 5 5 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 AMK77143.1 - 9.2e-08 32.2 1.6 9.2e-08 32.2 1.6 4.1 4 0 0 4 4 4 1 Tar ligand binding domain homologue MtrF PF09472.10 AMK77143.1 - 0.044 13.2 0.2 8.3 5.9 0.0 2.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) CorA PF01544.18 AMK77143.1 - 0.093 12.0 13.5 1.3 8.3 0.3 3.4 3 1 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 AMK77143.1 - 0.76 9.8 17.4 6.7 6.8 1.9 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 AMK77143.1 - 1 10.0 16.6 4.7 7.8 0.7 4.4 3 2 1 4 4 4 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 AMK77143.1 - 1.3 9.4 4.0 3 8.3 0.4 3.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 AMK77143.1 - 4 7.6 23.1 6.8 6.8 1.8 4.4 3 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase HAD_2 PF13419.6 AMK77144.1 - 3.2e-13 50.1 0.3 1.7e-12 47.8 0.3 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK77144.1 - 2.6e-08 34.5 0.8 5.6e-08 33.4 0.3 1.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK77144.1 - 1.7e-06 28.5 0.1 1e-05 25.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 AMK77144.1 - 0.0012 18.6 0.0 0.0038 17.0 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 AMK77144.1 - 0.0017 18.4 0.0 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DEAD PF00270.29 AMK77145.1 - 1.6e-46 158.2 0.1 8.5e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK77145.1 - 4.4e-32 110.7 0.1 1.1e-29 103.0 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 AMK77145.1 - 1.1e-07 32.0 0.0 3.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AMK77145.1 - 0.014 14.8 0.1 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Thioredoxin_8 PF13905.6 AMK77145.1 - 0.02 15.2 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like ERCC3_RAD25_C PF16203.5 AMK77145.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Thioredoxin PF00085.20 AMK77146.1 - 3e-34 117.1 0.0 3.3e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AMK77146.1 - 2.9e-08 34.1 0.0 2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AMK77146.1 - 2.5e-07 30.9 0.0 0.00013 22.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 AMK77146.1 - 6.4e-05 22.7 0.0 7.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 AMK77146.1 - 0.00029 20.7 0.0 0.00034 20.5 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AMK77146.1 - 0.00047 20.3 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 AMK77146.1 - 0.00071 19.0 0.0 0.00086 18.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 AMK77146.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 AMK77146.1 - 0.0064 16.4 0.0 0.0077 16.1 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK77146.1 - 0.008 15.9 0.0 0.011 15.4 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_6 PF13848.6 AMK77146.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.14 AMK77146.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 AMK77146.1 - 0.025 14.4 0.0 0.68 9.7 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Peptidase_M24 PF00557.24 AMK77146.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 HyaE PF07449.11 AMK77146.1 - 0.17 11.9 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Rho_RNA_bind PF07497.12 AMK77147.1 - 2.6e-32 110.5 0.0 4.8e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AMK77147.1 - 2.8e-23 82.7 0.1 3.9e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AMK77147.1 - 1.5e-15 56.8 4.3 3.4e-15 55.7 4.3 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NACHT PF05729.12 AMK77147.1 - 0.0004 20.3 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain OB_RNB PF08206.11 AMK77147.1 - 0.0011 18.6 0.0 0.0028 17.3 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_25 PF13481.6 AMK77147.1 - 0.0025 17.4 0.1 0.0079 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain Mor PF08765.11 AMK77147.1 - 0.011 15.7 0.1 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family AAA PF00004.29 AMK77147.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1912 PF08930.10 AMK77147.1 - 0.14 12.4 0.1 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) ABC_membrane_2 PF06472.15 AMK77148.1 - 3.4e-43 148.0 1.7 5.2e-43 147.4 1.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 AMK77148.1 - 1.5e-19 70.6 2.4 2e-19 70.2 2.4 1.1 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 AMK77148.1 - 0.002 18.6 0.0 0.0098 16.4 0.0 2.1 1 1 0 1 1 1 1 ABC transporter Cellulase PF00150.18 AMK77149.1 - 1.2e-16 61.0 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 AMK77149.1 - 0.0042 16.5 0.2 0.37 10.1 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase SlyX PF04102.12 AMK77150.1 - 0.00018 22.1 0.7 0.0002 21.9 0.7 1.2 1 0 0 1 1 1 1 SlyX FliJ PF02050.16 AMK77150.1 - 0.0018 18.5 1.3 0.0022 18.2 1.3 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein DUF16 PF01519.16 AMK77150.1 - 0.0034 17.8 0.1 0.0038 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF16 ApoLp-III PF07464.11 AMK77150.1 - 0.0059 16.7 0.4 0.0069 16.5 0.4 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) IFT57 PF10498.9 AMK77150.1 - 0.012 14.6 0.1 0.013 14.5 0.1 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.20 AMK77150.1 - 0.015 15.2 1.4 0.018 15.0 1.4 1.1 1 0 0 1 1 1 0 Prefoldin subunit FliD_C PF07195.12 AMK77150.1 - 0.023 14.1 0.1 0.024 14.0 0.1 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 AMK77150.1 - 0.038 14.2 0.1 0.039 14.1 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 AMK77150.1 - 0.039 13.7 2.3 0.053 13.3 2.3 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 AMK77150.1 - 0.085 12.2 0.1 0.085 12.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rad10 PF03834.14 AMK77150.1 - 0.097 12.7 0.1 0.12 12.4 0.1 1.2 1 1 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Fe-S_assembly PF04384.13 AMK77150.1 - 0.1 13.2 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Iron-sulphur cluster assembly MoaE PF02391.17 AMK77151.1 - 5e-31 107.3 0.0 6.2e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 AMK77152.1 - 7.9e-13 48.9 0.0 9e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 ThiS family MoaC PF01967.21 AMK77153.1 - 2.3e-57 192.9 1.4 2.6e-57 192.7 1.4 1.0 1 0 0 1 1 1 1 MoaC family DUF5436 PF17504.2 AMK77153.1 - 0.14 12.5 0.1 0.29 11.5 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5436) Lipoprotein_18 PF06804.11 AMK77154.1 - 8.6e-08 31.6 0.0 9.8e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 NlpB/DapX lipoprotein DUF3546 PF12066.8 AMK77154.1 - 0.025 14.8 0.1 0.044 14.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3546) CN_hydrolase PF00795.22 AMK77155.1 - 6.6e-56 189.5 0.0 7.3e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3971 PF13116.6 AMK77156.1 - 2.6e-53 181.5 4.7 4e-53 180.9 0.1 3.4 4 1 1 5 5 5 1 Protein of unknown function AsmA_2 PF13502.6 AMK77156.1 - 8.7e-42 143.2 15.3 1.1e-40 139.6 3.6 3.8 3 1 1 4 4 4 2 AsmA-like C-terminal region AvrPtoB_bdg PF16847.5 AMK77156.1 - 0.018 15.5 0.4 6.4 7.3 0.0 3.4 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain RNase_E_G PF10150.9 AMK77157.1 - 1.8e-96 322.7 1.5 2.3e-96 322.3 0.7 1.6 2 0 0 2 2 2 1 Ribonuclease E/G family S1 PF00575.23 AMK77157.1 - 1.3e-08 35.1 0.0 4.7e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 S1 RNA binding domain Maf PF02545.14 AMK77158.1 - 2.7e-54 183.5 0.0 3e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SPOUT_MTase PF02590.17 AMK77159.1 - 1.2e-50 171.4 0.0 1.4e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase EAL PF00563.20 AMK77160.1 - 6.2e-62 209.2 0.1 1.5e-61 207.9 0.1 1.7 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK77160.1 - 2.6e-44 150.8 0.0 6.7e-44 149.5 0.0 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 AMK77160.1 - 0.025 14.8 0.0 0.44 10.8 0.0 3.0 3 0 0 3 3 3 0 GGDEF-like domain Lactamase_B PF00753.27 AMK77161.1 - 1.7e-22 80.4 0.0 2.3e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK77161.1 - 0.00046 19.8 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Proton_antipo_M PF00361.20 AMK77162.1 - 1.3e-68 231.4 24.6 1.3e-68 231.4 24.6 2.1 2 1 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 AMK77162.1 - 0.83 9.8 14.7 0.26 11.4 7.9 3.5 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF2309 PF10070.9 AMK77164.1 - 1.2e-271 903.4 1.6 1.4e-271 903.2 1.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) Proton_antipo_M PF00361.20 AMK77165.1 - 6.9e-39 133.8 9.3 6.9e-39 133.8 9.3 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AMK77165.1 - 7e-06 26.0 1.2 7e-06 26.0 1.2 3.1 3 0 0 3 3 3 2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 AMK77166.1 - 2e-37 129.0 25.2 2e-37 129.0 25.2 2.0 1 1 1 2 2 2 1 Proton-conducting membrane transporter Rab5ip PF07019.12 AMK77166.1 - 0.0031 18.1 3.7 0.029 15.0 3.7 2.7 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Proton_antipo_M PF00361.20 AMK77167.1 - 1.1e-65 221.7 22.3 1.9e-65 221.0 22.3 1.4 1 0 0 1 1 1 1 Proton-conducting membrane transporter Pro_CA PF00484.19 AMK77168.1 - 5.5e-50 169.7 0.1 6.7e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Sulfate_transp PF00916.20 AMK77169.1 - 1.5e-51 175.4 21.2 1.5e-51 175.4 21.2 1.4 1 1 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 AMK77169.1 - 3.4e-05 24.2 2.0 3.4e-05 24.2 2.0 4.1 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily PsaL PF02605.15 AMK77169.1 - 0.13 11.9 1.9 3.6 7.2 0.0 2.9 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI PAS_3 PF08447.12 AMK77170.1 - 5.2e-10 39.5 0.0 9.1e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold TraX PF05857.11 AMK77170.1 - 0.023 14.8 7.2 0.036 14.1 7.2 1.3 1 0 0 1 1 1 0 TraX protein PAS_9 PF13426.7 AMK77170.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 PAS domain HATPase_c PF02518.26 AMK77171.1 - 7.2e-25 87.7 0.0 1.4e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK77171.1 - 3.3e-22 78.8 0.0 7.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AMK77171.1 - 5.8e-22 77.5 2.0 8.4e-21 73.8 0.1 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AMK77171.1 - 4.5e-18 65.3 0.3 1.3e-11 44.5 0.0 3.2 3 1 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AMK77171.1 - 6.1e-15 54.8 0.3 4.6e-08 32.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 AMK77171.1 - 3.9e-14 52.8 0.0 6.6e-08 32.8 0.0 2.9 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AMK77171.1 - 2.1e-13 50.5 0.2 1.5e-05 25.2 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AMK77171.1 - 6.4e-09 36.0 0.0 0.00023 21.4 0.0 2.8 3 0 0 3 3 3 2 PAS fold HATPase_c_2 PF13581.6 AMK77171.1 - 2.7e-05 24.1 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AMK77171.1 - 0.0012 19.0 0.3 0.022 14.9 0.2 3.0 2 1 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 AMK77171.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK77171.1 - 0.021 14.8 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 GHKL domain APH PF01636.23 AMK77172.1 - 1.9e-23 83.6 0.3 2.7e-23 83.2 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ham1p_like PF01725.16 AMK77173.1 - 1.1e-61 208.0 0.0 1.2e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RNase_PH PF01138.21 AMK77174.1 - 3e-22 79.5 0.0 4.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AMK77174.1 - 8.6e-11 41.7 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pkinase PF00069.25 AMK77175.1 - 1.6e-31 109.6 0.0 4.8e-31 108.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AMK77175.1 - 2.2e-17 63.2 0.0 9.2e-16 57.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AMK77175.1 - 0.0027 17.7 0.8 0.0066 16.4 0.1 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 AMK77175.1 - 0.0096 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 AMK77175.1 - 0.0096 14.9 1.8 0.048 12.6 0.1 2.1 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase YicC_N PF03755.13 AMK77176.1 - 2.4e-38 132.0 0.6 2.4e-38 132.0 0.6 1.9 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 AMK77176.1 - 1e-35 121.5 3.5 1e-35 121.5 3.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) Arm-DNA-bind_3 PF13356.6 AMK77177.1 - 0.00017 21.9 0.7 0.00038 20.8 0.7 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 AMK77177.1 - 0.031 14.6 0.4 0.052 13.8 0.4 1.5 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DsbC_N PF10411.9 AMK77177.1 - 0.046 13.2 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus SMBP PF16785.5 AMK77178.1 - 2.8e-29 101.5 23.0 3.1e-29 101.4 23.0 1.0 1 0 0 1 1 1 1 Small metal-binding protein TPR_12 PF13424.6 AMK77178.1 - 0.0062 16.8 3.6 0.018 15.3 0.8 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 AMK77178.1 - 0.083 13.8 1.6 3.5 8.7 0.1 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat THDPS_N_2 PF14805.6 AMK77178.1 - 0.13 12.5 2.0 2.9 8.2 0.5 2.8 2 1 1 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF2564 PF10819.8 AMK77178.1 - 0.66 10.4 9.8 1.2 9.6 4.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) HEPN PF05168.14 AMK77178.1 - 0.71 10.0 5.5 1.7 8.8 4.9 2.0 1 1 1 2 2 2 0 HEPN domain PIG-S PF10510.9 AMK77178.1 - 0.84 8.4 4.6 7 5.3 0.2 2.0 1 1 1 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF4398 PF14346.6 AMK77178.1 - 1.1 10.0 7.5 2 9.1 6.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) ANAPC5 PF12862.7 AMK77178.1 - 1.3 9.1 5.5 7.9 6.6 0.2 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 AMK77178.1 - 1.5 8.9 6.4 5.2 7.2 1.5 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Oxidored_FMN PF00724.20 AMK77179.1 - 1.2e-78 264.8 0.0 2e-78 264.1 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Polyketide_cyc2 PF10604.9 AMK77180.1 - 3.3e-10 40.4 0.6 4e-10 40.1 0.6 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 AMK77180.1 - 5.3e-07 29.9 0.3 6.9e-07 29.5 0.3 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 AMK77180.1 - 0.0077 16.4 0.2 0.0099 16.1 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EAL PF00563.20 AMK77181.1 - 1e-64 218.3 0.0 1.3e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 EAL domain CZB PF13682.6 AMK77181.1 - 1.9e-12 47.4 0.6 4.5e-12 46.2 0.3 1.9 2 0 0 2 2 2 1 Chemoreceptor zinc-binding domain DUF4166 PF13761.6 AMK77182.1 - 1.5e-38 132.4 0.0 1.7e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4166) DUF2269 PF10027.9 AMK77183.1 - 4.7e-49 166.3 12.1 5.2e-49 166.1 12.1 1.0 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DoxX_3 PF13781.6 AMK77184.1 - 3.8e-24 85.3 10.4 8.1e-24 84.2 10.4 1.6 1 0 0 1 1 1 1 DoxX-like family NAD_binding_10 PF13460.6 AMK77184.1 - 1.9e-18 67.0 0.0 2.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AMK77184.1 - 2.2e-13 50.2 0.0 7.6e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 AMK77184.1 - 6.7e-06 25.5 0.0 0.0044 16.2 0.1 2.4 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AMK77184.1 - 3.5e-05 23.3 0.0 8.4e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 AMK77184.1 - 4.9e-05 22.6 0.0 0.00032 19.9 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 AMK77184.1 - 0.00042 19.9 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 AMK77184.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF2768 PF10966.8 AMK77184.1 - 0.044 14.2 0.8 0.089 13.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) GDP_Man_Dehyd PF16363.5 AMK77184.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HTH_18 PF12833.7 AMK77185.1 - 4.6e-20 71.7 0.1 8.3e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AMK77185.1 - 3.8e-08 33.2 0.4 2.3e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF423 PF04241.15 AMK77185.1 - 0.36 11.1 5.9 11 6.3 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF423) ECF_trnsprt PF12822.7 AMK77185.1 - 1.4 9.0 11.4 0.35 11.0 3.1 2.3 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Uma2 PF05685.12 AMK77186.1 - 4.3e-27 94.7 0.0 5e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Fumerase PF05681.14 AMK77187.1 - 4.2e-98 328.1 0.0 7.6e-98 327.2 0.0 1.4 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 AMK77187.1 - 7.5e-82 273.6 0.0 1.1e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus NfeD PF01957.18 AMK77188.1 - 1.8e-13 50.7 0.1 1.8e-13 50.7 0.1 1.8 2 1 0 2 2 2 1 NfeD-like C-terminal, partner-binding Ac81 PF05820.11 AMK77188.1 - 0.13 11.8 0.3 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 DUF3093 PF11292.8 AMK77188.1 - 1.9 8.8 8.4 3.9 7.7 8.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3093) Band_7 PF01145.25 AMK77189.1 - 1.4e-32 113.1 0.8 1.4e-32 113.1 0.8 2.1 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 AMK77189.1 - 3.7e-07 30.1 0.7 7.9e-07 29.0 0.7 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 AMK77189.1 - 0.013 15.3 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family LON_substr_bdg PF02190.16 AMK77189.1 - 0.059 13.2 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain MIase PF02426.16 AMK77189.1 - 0.64 10.2 2.4 7.8 6.7 0.2 2.4 1 1 1 2 2 2 0 Muconolactone delta-isomerase Flot PF15975.5 AMK77189.1 - 5.4 7.2 16.8 0.29 11.3 6.5 2.8 2 1 1 3 3 3 0 Flotillin Claudin_2 PF13903.6 AMK77190.1 - 0.014 15.1 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction S_4TM PF18159.1 AMK77190.1 - 0.044 13.1 0.7 0.051 12.9 0.7 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Gram_pos_anchor PF00746.21 AMK77190.1 - 0.2 11.6 0.8 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Phage_holin_6_1 PF09682.10 AMK77190.1 - 0.27 11.7 4.9 1.3 9.5 4.9 1.8 1 1 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4064 PF13273.6 AMK77190.1 - 3.1 8.1 7.9 8.2 6.8 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) HemY_N PF07219.13 AMK77190.1 - 7.2 6.9 7.8 17 5.7 1.1 2.1 2 0 0 2 2 2 0 HemY protein N-terminus DUF3488 PF11992.8 AMK77191.1 - 2.7e-96 322.3 8.1 2.7e-96 322.3 8.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3488) Transglut_core PF01841.19 AMK77191.1 - 1.9e-23 83.1 0.0 3.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF4129 PF13559.6 AMK77191.1 - 4e-08 33.4 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) DUF58 PF01882.18 AMK77192.1 - 4e-16 59.1 0.0 7.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 AAA_3 PF07726.11 AMK77193.1 - 9.2e-62 206.7 0.1 1.4e-61 206.1 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AMK77193.1 - 5.2e-14 51.8 0.2 1.5e-13 50.3 0.2 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AMK77193.1 - 1.9e-13 50.6 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK77193.1 - 0.00012 22.5 0.0 0.00019 21.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AMK77193.1 - 0.00018 21.3 0.1 0.001 18.9 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AMK77193.1 - 0.0041 17.6 0.0 0.013 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 AMK77193.1 - 0.0045 16.7 0.0 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 AMK77193.1 - 0.0047 16.1 0.0 0.0075 15.4 0.0 1.4 1 1 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 AMK77193.1 - 0.012 15.0 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI zf-dskA_traR PF01258.17 AMK77194.1 - 8.7e-14 51.2 1.6 1.3e-13 50.7 1.6 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Apolipoprotein PF01442.18 AMK77194.1 - 0.0058 16.5 1.0 0.0075 16.2 1.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 AMK77194.1 - 0.011 16.2 0.7 0.044 14.3 0.7 1.8 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 AMK77194.1 - 0.04 14.5 1.1 1.2 9.8 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) zf_C2H2_13 PF18508.1 AMK77194.1 - 0.071 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc finger domain T2SSE PF00437.20 AMK77195.1 - 1.7e-48 165.0 0.1 7.4e-47 159.7 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 AMK77195.1 - 3.3e-05 23.7 0.1 0.00029 20.6 0.0 2.4 2 1 2 4 4 4 1 AAA domain AAA_22 PF13401.6 AMK77195.1 - 8.1e-05 22.9 0.1 0.00027 21.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK77195.1 - 0.00011 21.8 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK77195.1 - 0.00028 21.3 0.0 0.00066 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.9 AMK77195.1 - 0.00059 19.1 0.0 0.01 15.1 0.0 2.5 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 AMK77195.1 - 0.00063 20.3 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AMK77195.1 - 0.0008 19.0 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_23 PF13476.6 AMK77195.1 - 0.00097 19.7 0.1 0.0022 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain TK PF00265.18 AMK77195.1 - 0.002 18.0 0.0 0.0071 16.2 0.0 1.8 1 1 1 2 2 2 1 Thymidine kinase DUF87 PF01935.17 AMK77195.1 - 0.003 17.7 0.1 0.0049 17.0 0.1 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_19 PF13245.6 AMK77195.1 - 0.0053 17.1 0.8 0.019 15.3 0.7 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK77195.1 - 0.0068 16.9 0.0 0.0099 16.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 AMK77195.1 - 0.0093 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.6 AMK77195.1 - 0.01 16.0 0.1 0.043 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AMK77195.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 AMK77195.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 AMK77195.1 - 0.011 15.7 0.2 0.11 12.4 0.1 2.3 1 1 1 2 2 2 0 NTPase SRP54 PF00448.22 AMK77195.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 AMK77195.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 AMK77195.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 AMK77195.1 - 0.029 14.3 0.0 0.33 10.9 0.0 2.5 3 0 0 3 3 2 0 NACHT domain AAA_25 PF13481.6 AMK77195.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 AMK77195.1 - 0.031 14.2 0.1 0.08 12.8 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 AMK77195.1 - 0.039 13.7 0.1 0.1 12.4 0.0 1.7 2 1 1 3 3 2 0 AAA domain AAA_27 PF13514.6 AMK77195.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AMK77195.1 - 0.046 13.0 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 AMK77195.1 - 0.046 13.0 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 AMK77195.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AMK77195.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 AMK77195.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AMK77195.1 - 0.096 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 AMK77195.1 - 0.11 12.9 0.6 1.3 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Asparaginase_C PF17763.1 AMK77195.1 - 0.11 12.7 0.1 7.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain DUF374 PF04028.13 AMK77195.1 - 0.11 12.0 0.2 9 5.9 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF374) KTI12 PF08433.10 AMK77195.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SLT_2 PF13406.6 AMK77196.1 - 8.1e-90 301.0 0.0 9.6e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT PF01464.20 AMK77196.1 - 0.00032 20.3 0.0 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AMK77196.1 - 0.0039 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase nlz1 PF12402.8 AMK77196.1 - 0.13 12.7 1.0 1.5 9.3 0.2 2.7 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 rve PF00665.26 AMK77197.1 - 1.3e-11 44.7 0.4 2.8e-11 43.6 0.1 1.6 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 AMK77197.1 - 1.3e-06 28.5 2.1 2.2e-06 27.7 2.1 1.4 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_IS240 PF13610.6 AMK77197.1 - 0.098 12.9 1.7 0.21 11.8 0.0 2.0 2 1 0 2 2 2 0 DDE domain HTH_Tnp_1 PF01527.20 AMK77198.1 - 4.2e-07 30.2 2.9 6e-07 29.7 2.9 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK77198.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 AMK77198.1 - 0.026 14.3 0.2 0.049 13.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain eIF3_subunit PF08597.10 AMK77198.1 - 0.033 14.1 3.8 0.036 14.0 3.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CCDC-167 PF15188.6 AMK77198.1 - 0.098 13.0 1.8 0.14 12.5 1.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Dimer_Tnp_Tn5 PF02281.16 AMK77199.1 - 4.2e-16 58.5 0.0 9.2e-16 57.4 0.0 1.5 1 1 0 1 1 1 1 Transposase Tn5 dimerisation domain MTHFR PF02219.17 AMK77200.1 - 3.3e-09 36.5 0.0 4.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AAA_31 PF13614.6 AMK77201.1 - 7.5e-36 123.7 0.0 1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK77201.1 - 8.2e-14 51.8 0.0 1.9e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 AMK77201.1 - 2.9e-11 43.3 0.1 5.5e-11 42.4 0.1 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AMK77201.1 - 3.3e-11 43.0 0.3 1.6e-10 40.7 0.3 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AMK77201.1 - 4e-07 29.5 0.2 4.7e-05 22.7 0.1 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CBP_BcsQ PF06564.12 AMK77201.1 - 5.1e-07 29.4 0.2 0.00021 20.8 0.4 2.6 2 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AMK77201.1 - 5.1e-05 22.9 0.0 0.0043 16.5 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 AMK77201.1 - 0.00079 18.8 0.2 0.0091 15.3 0.1 2.3 2 1 0 2 2 2 1 VirC1 protein CLP1_P PF16575.5 AMK77201.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop LpxK PF02606.14 AMK77201.1 - 0.023 13.8 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase SRP54 PF00448.22 AMK77201.1 - 0.076 12.6 0.6 0.35 10.5 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 AMK77201.1 - 0.13 11.9 0.4 0.36 10.4 0.4 1.8 1 1 0 1 1 1 0 AAA domain HATPase_c PF02518.26 AMK77202.1 - 8.3e-22 77.8 0.0 9.2e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK77202.1 - 4.2e-05 23.5 0.0 5.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK77202.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 AMK77202.1 - 0.029 14.2 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain HATPase_c_5 PF14501.6 AMK77202.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.3 1 1 0 1 1 1 0 GHKL domain Transgly PF00912.22 AMK77203.1 - 1.9e-51 174.1 0.0 2.3e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase DUF615 PF04751.14 AMK77204.1 - 6.2e-42 143.2 9.8 7.5e-42 142.9 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF615) POPLD PF08170.12 AMK77204.1 - 0.25 11.7 1.1 0.98 9.8 0.2 2.1 2 0 0 2 2 2 0 POPLD (NUC188) domain DctQ PF04290.12 AMK77205.1 - 0.013 15.4 4.4 0.014 15.3 4.4 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2970 PF11174.8 AMK77205.1 - 0.014 15.2 1.6 0.03 14.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF4131 PF13567.6 AMK77205.1 - 0.75 9.4 2.8 0.84 9.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RdgC PF04381.12 AMK77206.1 - 3.1e-124 414.1 0.9 3.5e-124 413.9 0.9 1.0 1 0 0 1 1 1 1 Putative exonuclease, RdgC MerR-DNA-bind PF09278.11 AMK77206.1 - 0.33 11.5 3.6 17 6.0 0.2 3.0 3 0 0 3 3 3 0 MerR, DNA binding YkuD PF03734.14 AMK77207.1 - 2.2e-23 83.3 0.0 4.1e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain LysM PF01476.20 AMK77207.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 LysM domain DUF5437 PF17505.2 AMK77207.1 - 0.21 11.6 0.8 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5437) Alanine_zipper PF11839.8 AMK77208.1 - 5.2e-17 62.0 26.6 7.1e-17 61.5 26.6 1.2 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein HrpB7 PF09486.10 AMK77208.1 - 0.0062 16.9 11.7 0.007 16.8 11.7 1.0 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) YscO PF07321.12 AMK77208.1 - 0.0063 16.5 4.9 0.008 16.1 4.9 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO Sugarporin_N PF11471.8 AMK77208.1 - 0.0093 15.9 4.7 0.0093 15.9 4.7 2.3 1 1 1 2 2 2 1 Maltoporin periplasmic N-terminal extension DUF3138 PF11336.8 AMK77208.1 - 0.14 10.7 17.2 0.16 10.6 17.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF501 PF04417.12 AMK77208.1 - 0.17 11.7 1.8 0.21 11.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3584 PF12128.8 AMK77208.1 - 0.22 9.0 5.9 0.24 8.9 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1702 PF08012.11 AMK77208.1 - 0.3 9.9 11.9 0.3 9.9 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) DUF3597 PF12200.8 AMK77208.1 - 0.8 10.3 7.1 1 9.9 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) YkuD PF03734.14 AMK77209.1 - 1.5e-17 64.3 0.1 1.9e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PGM_PMM_I PF02878.16 AMK77210.1 - 6.5e-36 123.1 0.0 1e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AMK77210.1 - 1.2e-29 102.8 0.0 2.2e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 AMK77210.1 - 2.4e-10 41.0 0.1 5.5e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 AMK77210.1 - 1.4e-06 28.4 0.0 3.7e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SpoIID PF08486.10 AMK77211.1 - 0.009 16.5 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 Stage II sporulation protein Robl_LC7 PF03259.17 AMK77211.1 - 0.08 12.7 0.1 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Roadblock/LC7 domain CSD PF00313.22 AMK77212.1 - 1.5e-24 85.6 0.2 1.7e-24 85.4 0.2 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AMK77212.1 - 0.054 13.2 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain Zeta_toxin PF06414.12 AMK77213.1 - 3.1e-14 52.7 0.0 9.8e-14 51.1 0.0 1.8 2 1 0 2 2 2 1 Zeta toxin DUF1175 PF06672.11 AMK77214.1 - 3.6e-56 190.3 0.0 5.1e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1175) DUF2135 PF09906.9 AMK77214.1 - 1.7e-05 25.1 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2135) SpoU_methylas_C PF12105.8 AMK77214.1 - 0.1 12.3 0.3 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal NLPC_P60 PF00877.19 AMK77214.1 - 0.11 12.6 0.0 0.63 10.1 0.0 2.1 1 1 0 1 1 1 0 NlpC/P60 family MG2 PF01835.19 AMK77217.1 - 3.7e-16 59.4 0.0 1e-13 51.5 0.0 4.7 5 0 0 5 5 5 1 MG2 domain A2M PF00207.22 AMK77217.1 - 6.4e-15 54.8 0.1 2.9e-14 52.7 0.1 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family bMG10 PF17973.1 AMK77217.1 - 8.5e-09 35.7 0.1 4.5e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M_BRD PF07703.14 AMK77217.1 - 2.8e-08 34.2 0.0 1.3e-07 32.1 0.0 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain TED_complement PF07678.14 AMK77217.1 - 7.9e-07 28.4 0.1 2e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 A-macroglobulin TED domain bMG3 PF11974.8 AMK77217.1 - 0.00088 19.3 1.5 0.0053 16.7 0.1 3.0 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain MG4 PF17789.1 AMK77217.1 - 0.0013 18.9 0.4 6.9 6.9 0.0 5.1 5 0 0 5 5 5 1 Macroglobulin domain MG4 Big_1 PF02369.16 AMK77217.1 - 0.053 13.5 0.7 17 5.5 0.0 3.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) DUF4713 PF15831.5 AMK77218.1 - 0.11 12.9 0.7 0.42 11.1 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) TMEM238 PF15125.6 AMK77218.1 - 0.64 10.3 9.6 0.92 9.7 4.1 2.8 2 0 0 2 2 2 0 TMEM238 protein family Tetraspanin PF00335.20 AMK77218.1 - 0.77 9.4 13.8 0.41 10.3 8.7 2.4 1 1 1 2 2 2 0 Tetraspanin family SUR7 PF06687.12 AMK77218.1 - 0.87 9.2 10.5 0.031 13.9 3.4 1.9 1 1 1 2 2 2 0 SUR7/PalI family SDF PF00375.18 AMK77219.1 - 6.6e-108 361.2 19.2 8.4e-108 360.9 19.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family PepSY_TM PF03929.16 AMK77220.1 - 2.3e-60 204.7 10.3 3.3e-60 204.2 10.3 1.2 1 0 0 1 1 1 1 PepSY-associated TM region PepSY_TM_like_2 PF16357.5 AMK77220.1 - 0.041 13.9 0.1 0.041 13.9 0.1 2.9 4 0 0 4 4 4 0 Putative PepSY_TM-like DUF4405 PF14358.6 AMK77220.1 - 0.066 13.8 8.4 2.5 8.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF2306 PF10067.9 AMK77220.1 - 0.11 12.7 7.3 9.9 6.4 0.2 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2306) Uma2 PF05685.12 AMK77221.1 - 4.3e-25 88.2 0.0 5.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease DUF1506 PF07405.11 AMK77221.1 - 0.028 14.6 0.4 0.056 13.6 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1506) DNA_pol_A PF00476.20 AMK77222.1 - 4.9e-153 509.6 0.0 6.6e-153 509.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AMK77222.1 - 1.3e-52 177.9 0.0 2.2e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 AMK77222.1 - 8.2e-40 136.4 3.8 1.1e-39 135.9 1.7 2.2 2 0 0 2 2 2 1 3'-5' exonuclease 5_3_exonuc PF01367.20 AMK77222.1 - 2.2e-33 114.7 0.2 3.2e-32 111.0 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 AMK77222.1 - 0.0064 16.6 0.0 0.085 13.0 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix motif Enoyl_reductase PF12241.8 AMK77222.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Lactamase_B_2 PF12706.7 AMK77223.1 - 4.3e-23 81.9 1.2 1.4e-22 80.2 1.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AMK77223.1 - 6e-08 32.9 0.2 1.3e-07 31.9 0.2 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 AMK77223.1 - 0.084 12.8 0.2 0.35 10.7 0.2 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DeoRC PF00455.22 AMK77223.1 - 0.095 12.6 0.3 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 DeoR C terminal sensor domain HTH_Tnp_1 PF01527.20 AMK77224.1 - 1.1e-06 28.8 0.1 1.3e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AMK77224.1 - 0.00081 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Com_YlbF PF06133.11 AMK77224.1 - 0.016 15.8 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA HTH_Tnp_ISL3 PF13542.6 AMK77224.1 - 0.099 12.1 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Acetyltransf_1 PF00583.25 AMK77225.1 - 5.6e-10 39.5 0.0 9.6e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AMK77225.1 - 1.1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AMK77225.1 - 4.6e-07 29.8 0.0 1.6e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AMK77225.1 - 8.9e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AMK77225.1 - 0.0035 17.4 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain VD10_N PF08476.10 AMK77225.1 - 0.17 11.6 0.2 0.28 10.9 0.2 1.3 1 0 0 1 1 1 0 Viral D10 N-terminal rve PF00665.26 AMK77227.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_5 PF01022.20 AMK77227.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AMK77227.1 - 0.00036 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AMK77227.1 - 0.0018 18.0 1.3 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AMK77227.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.12 AMK77227.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AMK77227.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK77227.1 - 0.037 13.8 0.1 0.89 9.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 AMK77227.1 - 0.038 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK77227.1 - 0.044 13.8 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 AMK77227.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 AMK77227.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 AMK77227.1 - 0.12 12.5 0.0 0.81 9.9 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AMK77227.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain IstB_IS21 PF01695.17 AMK77228.1 - 4.8e-56 189.3 0.0 6.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK77228.1 - 2e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK77228.1 - 4.1e-06 26.4 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AMK77228.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AMK77228.1 - 0.0068 15.3 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK77228.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AMK77228.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AMK77228.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AMK77228.1 - 0.031 14.5 0.5 0.28 11.5 0.3 2.1 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 AMK77228.1 - 0.031 13.3 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 AMK77228.1 - 0.044 13.5 0.2 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 AMK77228.1 - 0.05 13.5 1.6 0.87 9.5 0.0 2.5 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 AMK77228.1 - 0.054 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AMK77228.1 - 0.096 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AMK77228.1 - 0.11 12.9 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 AMK77228.1 - 0.12 12.1 0.3 0.33 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK77228.1 - 0.13 12.6 2.0 0.25 11.6 1.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK77228.1 - 0.17 11.9 0.3 0.47 10.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AMK77228.1 - 0.32 11.0 1.2 0.73 9.8 0.6 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE rve PF00665.26 AMK77230.1 - 1.7e-27 96.0 0.0 4e-27 94.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 AMK77230.1 - 9.3e-23 79.8 0.2 2.2e-22 78.6 0.2 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AMK77230.1 - 4e-07 30.1 0.5 7.6e-07 29.2 0.5 1.5 1 0 0 1 1 1 1 HTH-like domain Rhomboid_SP PF12595.8 AMK77230.1 - 0.055 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Rhomboid serine protease DDE_Tnp_IS240 PF13610.6 AMK77230.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 DDE domain DUF3108 PF11306.8 AMK77230.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) Glycos_transf_2 PF00535.26 AMK77232.1 - 4.6e-33 114.4 0.1 8e-33 113.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK77232.1 - 3e-08 33.8 0.0 3.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK77232.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK77232.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AMK77232.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Methyltransf_23 PF13489.6 AMK77233.1 - 2.1e-09 37.4 0.0 3.7e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77233.1 - 0.0036 18.0 0.1 0.0082 16.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77233.1 - 0.08 13.6 0.5 0.26 12.0 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 AMK77233.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GtrA PF04138.14 AMK77234.1 - 1.4e-18 67.3 16.4 1.6e-18 67.0 16.4 1.1 1 0 0 1 1 1 1 GtrA-like protein 7TMR-DISM_7TM PF07695.11 AMK77234.1 - 0.021 14.7 9.1 0.027 14.4 9.1 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF3429 PF11911.8 AMK77234.1 - 0.068 13.5 5.8 0.089 13.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) SK_channel PF03530.14 AMK77234.1 - 0.59 10.1 4.9 0.38 10.7 0.3 2.0 2 0 0 2 2 2 0 Calcium-activated SK potassium channel DciA PF05258.12 AMK77235.1 - 1.3e-06 28.7 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA LpxC PF03331.13 AMK77236.1 - 1.5e-108 362.4 0.0 1.7e-108 362.2 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Tubulin PF00091.25 AMK77237.1 - 2.4e-37 129.1 0.4 3.7e-37 128.4 0.4 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AMK77237.1 - 8.7e-29 99.7 2.5 2.6e-28 98.2 2.5 1.9 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 AMK77237.1 - 0.0038 17.1 0.6 0.01 15.8 0.5 1.8 1 1 0 1 1 1 1 NAD(P)H-binding FtsA PF14450.6 AMK77238.1 - 1.7e-40 137.6 5.2 5.4e-27 94.2 0.1 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AMK77238.1 - 8.9e-34 115.7 1.9 8.9e-34 115.7 1.9 2.1 2 0 0 2 2 2 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 AMK77238.1 - 1.1e-16 60.6 1.4 1.1e-16 60.6 1.4 2.2 1 1 1 2 2 2 1 MreB/Mbl protein EutA PF06277.11 AMK77238.1 - 8.4e-08 31.5 0.9 3.5e-07 29.4 0.4 2.1 2 1 0 2 2 2 1 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 AMK77238.1 - 4.2e-06 26.0 1.0 0.00024 20.3 0.0 2.8 2 1 0 3 3 3 1 Type IV pilus assembly protein PilM; DDR PF08841.10 AMK77238.1 - 1.7e-05 24.0 1.6 2.9e-05 23.2 0.9 1.5 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 AMK77238.1 - 0.00077 17.8 0.4 0.043 12.0 0.1 2.4 1 1 1 2 2 2 1 Hsp70 protein GAPES3 PF17154.4 AMK77238.1 - 0.027 14.4 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain SrfB PF07520.11 AMK77238.1 - 0.044 11.7 0.2 0.064 11.1 0.2 1.2 1 0 0 1 1 1 0 Virulence factor SrfB Actin PF00022.19 AMK77238.1 - 0.061 11.9 0.2 0.52 8.9 0.0 2.3 3 0 0 3 3 3 0 Actin BcrAD_BadFG PF01869.20 AMK77238.1 - 0.47 9.9 5.2 0.53 9.7 0.5 2.7 2 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family FtsQ PF03799.15 AMK77239.1 - 3.5e-18 66.5 0.2 6.6e-18 65.6 0.2 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ POTRA_1 PF08478.10 AMK77239.1 - 1.3e-16 60.6 0.0 6.3e-16 58.4 0.1 2.0 2 0 0 2 2 2 1 POTRA domain, FtsQ-type Dala_Dala_lig_C PF07478.13 AMK77240.1 - 9.9e-56 188.5 0.0 1.3e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 AMK77240.1 - 5.2e-19 68.6 0.6 1.2e-17 64.3 0.6 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 AMK77240.1 - 2e-09 37.3 0.0 4.5e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AMK77240.1 - 2e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AMK77240.1 - 2.2e-07 30.7 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 AMK77240.1 - 3.1e-07 30.1 0.0 1.3e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AMK77240.1 - 3.4e-07 30.0 0.0 2.8e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AMK77240.1 - 0.0014 18.0 0.0 0.17 11.1 0.0 2.4 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp TTL PF03133.15 AMK77240.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 AMK77240.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp MurB_C PF02873.16 AMK77241.1 - 2.1e-31 108.4 0.0 3.6e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 AMK77241.1 - 2.6e-17 62.8 0.2 6.4e-17 61.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Mur_ligase PF01225.25 AMK77242.1 - 3.7e-27 94.5 0.1 7.2e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 AMK77242.1 - 9e-26 91.1 0.0 1.4e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AMK77242.1 - 4.9e-22 78.0 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Glyco_transf_28 PF03033.20 AMK77243.1 - 4.5e-41 140.2 0.4 1e-40 139.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 AMK77243.1 - 3.6e-40 137.7 0.1 5.8e-40 137.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 AMK77243.1 - 1.4e-05 25.1 0.0 5.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK77243.1 - 9.1e-05 22.9 0.4 0.00021 21.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AMK77243.1 - 0.012 16.0 0.1 0.028 14.8 0.1 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_3 PF13528.6 AMK77243.1 - 0.052 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 UDPGT PF00201.18 AMK77243.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase FTSW_RODA_SPOVE PF01098.19 AMK77244.1 - 1.6e-95 320.2 31.1 1.8e-95 320.0 31.1 1.0 1 0 0 1 1 1 1 Cell cycle protein DUF4731 PF15875.5 AMK77244.1 - 2.9 8.1 8.4 0.79 10.0 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4731) Mur_ligase_M PF08245.12 AMK77245.1 - 1e-30 107.2 0.3 2.6e-30 105.9 0.2 1.7 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AMK77245.1 - 4.6e-09 36.4 0.0 1.6e-07 31.4 0.0 3.0 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain TrkA_N PF02254.18 AMK77245.1 - 0.0033 17.7 0.0 0.098 12.9 0.0 3.0 3 1 0 3 3 3 1 TrkA-N domain Pyr_redox_2 PF07992.14 AMK77245.1 - 0.031 13.5 0.1 0.11 11.7 0.0 2.1 2 2 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AMK77245.1 - 0.059 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 AMK77245.1 - 0.081 13.4 0.1 0.33 11.4 0.0 2.1 2 1 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 AMK77245.1 - 0.086 12.4 0.2 10 5.6 0.0 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase Glycos_transf_4 PF00953.21 AMK77246.1 - 2.9e-36 124.9 16.9 2.9e-36 124.9 16.9 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 AMK77246.1 - 4.3e-05 22.8 2.2 4.3e-05 22.8 2.2 2.6 2 0 0 2 2 2 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Mur_ligase_M PF08245.12 AMK77247.1 - 9e-49 166.1 3.2 1.5e-48 165.4 3.2 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AMK77247.1 - 9.4e-12 45.0 0.0 4.1e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AMK77247.1 - 3.6e-11 43.2 0.1 3.4e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Mur ligase family, catalytic domain LpxD PF04613.14 AMK77247.1 - 0.032 14.0 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Mur_ligase_M PF08245.12 AMK77248.1 - 2.8e-48 164.5 0.0 1e-47 162.6 0.0 1.8 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AMK77248.1 - 1.1e-22 80.1 0.0 2.9e-21 75.5 0.0 2.8 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 AMK77248.1 - 5.9e-10 39.3 0.2 1.4e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Glycos_transf_2 PF00535.26 AMK77248.1 - 0.00021 21.2 0.5 0.062 13.1 0.3 3.2 2 1 1 3 3 3 1 Glycosyl transferase family 2 DcrB PF08786.11 AMK77248.1 - 0.033 14.3 0.3 0.11 12.7 0.1 2.0 2 1 0 2 2 2 0 DcrB MoCF_biosynth PF00994.24 AMK77248.1 - 0.099 12.3 0.2 2.1 8.0 0.2 2.3 2 0 0 2 2 2 0 Probable molybdopterin binding domain Transpeptidase PF00905.22 AMK77249.1 - 2.6e-75 253.5 0.1 3.3e-75 253.1 0.1 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AMK77249.1 - 1.1e-24 87.8 1.7 3.5e-23 82.9 1.7 2.3 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain FtsL PF04999.13 AMK77250.1 - 5.3e-19 68.0 0.7 5.6e-19 67.9 0.7 1.0 1 0 0 1 1 1 1 Cell division protein FtsL Methyltransf_5 PF01795.19 AMK77251.1 - 8.7e-111 370.3 0.2 9.9e-111 370.1 0.2 1.0 1 0 0 1 1 1 1 MraW methylase family Ubie_methyltran PF01209.18 AMK77251.1 - 0.072 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MraZ PF02381.18 AMK77252.1 - 7.6e-36 121.9 0.2 9.1e-18 64.0 0.1 2.6 2 1 0 2 2 2 2 MraZ protein, putative antitoxin-like NAD_Gly3P_dh_C PF07479.14 AMK77253.1 - 4.3e-54 182.7 0.2 6.7e-54 182.0 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 AMK77253.1 - 5.9e-35 120.6 0.0 9.2e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 AMK77253.1 - 0.0057 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SecB PF02556.14 AMK77254.1 - 9.2e-57 190.9 0.1 1.1e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB Head-tail_con PF12236.8 AMK77254.1 - 0.053 12.0 0.0 0.07 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Rhodanese PF00581.20 AMK77255.1 - 1.2e-18 67.6 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain ATPgrasp_TupA PF14305.6 AMK77255.1 - 0.037 13.8 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp HTH_5 PF01022.20 AMK77256.1 - 2.9e-13 49.5 0.1 4.3e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AMK77256.1 - 1.6e-09 37.7 0.0 2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AMK77256.1 - 1e-05 25.0 0.1 1.9e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 AMK77256.1 - 2.8e-05 24.2 0.1 3.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AMK77256.1 - 9.6e-05 22.2 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AMK77256.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HNF-1_N PF04814.13 AMK77256.1 - 0.0012 19.5 0.0 0.0013 19.4 0.0 1.1 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus TFIIE_alpha PF02002.17 AMK77256.1 - 0.0014 18.4 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit LexA_DNA_bind PF01726.16 AMK77256.1 - 0.0022 17.7 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 LexA DNA binding domain MarR PF01047.22 AMK77256.1 - 0.0031 17.4 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AMK77256.1 - 0.0037 17.6 0.0 0.0042 17.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AMK77256.1 - 0.0041 17.1 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 AMK77256.1 - 0.017 15.1 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 HTH domain DpnI_C PF17726.1 AMK77256.1 - 0.023 14.8 0.1 0.054 13.6 0.0 1.6 1 1 0 1 1 1 0 Dam-replacing HTH domain HTH_40 PF14493.6 AMK77256.1 - 0.038 14.5 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Penicillinase_R PF03965.16 AMK77256.1 - 0.054 13.8 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor Mob_synth_C PF06463.13 AMK77256.1 - 0.065 13.2 0.0 0.5 10.3 0.0 1.9 1 1 1 2 2 2 0 Molybdenum Cofactor Synthesis C DprA_WH PF17782.1 AMK77256.1 - 0.068 13.3 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 DprA winged helix domain PuR_N PF09182.10 AMK77256.1 - 0.11 12.4 0.2 0.21 11.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Fe_dep_repress PF01325.19 AMK77256.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Peptidase_M23 PF01551.22 AMK77257.1 - 2.4e-24 85.3 0.5 5.2e-24 84.3 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M23 AIP3 PF03915.13 AMK77257.1 - 0.00015 21.0 17.1 0.00021 20.6 17.1 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Lebercilin PF15619.6 AMK77257.1 - 0.0034 17.1 9.0 0.0034 17.1 9.0 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 AMK77257.1 - 0.0072 16.9 9.5 0.0072 16.9 9.5 2.4 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF724 PF05266.14 AMK77257.1 - 0.013 15.3 4.4 0.013 15.3 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SKA1 PF07160.12 AMK77257.1 - 0.035 14.0 17.4 0.077 12.8 2.0 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 FapA PF03961.13 AMK77257.1 - 0.18 10.4 21.6 0.66 8.5 6.6 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3450 PF11932.8 AMK77257.1 - 0.37 10.1 25.9 0.043 13.1 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) VGPC1_C PF16799.5 AMK77257.1 - 0.65 10.0 9.9 9 6.4 4.2 2.6 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 GAS PF13851.6 AMK77257.1 - 1.1 8.5 33.4 0.95 8.8 12.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 AMK77257.1 - 1.4 9.0 20.4 0.051 13.7 1.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 AMK77257.1 - 1.5 8.8 12.7 0.15 12.1 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlgN PF05130.12 AMK77257.1 - 2 8.9 23.9 5.4 7.5 12.2 2.4 2 0 0 2 2 2 0 FlgN protein FixO PF02433.15 AMK77257.1 - 5.4 6.4 11.3 1.9 7.9 3.6 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Noelin-1 PF12308.8 AMK77257.1 - 5.9 6.9 12.0 0.18 11.8 1.1 2.7 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF948 PF06103.11 AMK77257.1 - 7.4 6.9 11.1 3.1 8.1 0.7 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.6 AMK77257.1 - 7.4 7.0 25.6 1.4 9.3 7.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.6 AMK77257.1 - 7.7 5.0 19.5 4.1 5.9 17.4 1.5 1 1 0 1 1 1 0 AAA domain DASH_Spc34 PF08657.10 AMK77257.1 - 7.8 6.2 17.9 12 5.6 15.5 2.1 1 1 1 2 2 1 0 DASH complex subunit Spc34 DUF1515 PF07439.11 AMK77257.1 - 8.8 6.4 8.1 23 5.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Peptidase_S41 PF03572.18 AMK77258.1 - 5.8e-56 188.6 0.1 8.7e-56 188.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 AMK77258.1 - 6.4e-14 52.0 0.4 3.5e-13 49.7 0.1 2.3 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 AMK77258.1 - 2.1e-13 49.9 0.3 4.9e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AMK77258.1 - 1.7e-08 34.7 0.5 4.5e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 PDZ domain DUF934 PF06073.12 AMK77259.1 - 5.9e-34 116.2 0.0 8.4e-34 115.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF934) NIR_SIR PF01077.22 AMK77260.1 - 7.2e-59 197.8 0.0 9.8e-45 151.9 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 AMK77260.1 - 4.2e-34 116.2 0.0 3.6e-16 58.8 0.0 3.2 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain CitMHS PF03600.16 AMK77261.1 - 8.4e-46 156.5 20.9 1.2e-45 156.0 20.9 1.2 1 0 0 1 1 1 1 Citrate transporter Acatn PF13000.7 AMK77262.1 - 1.1e-11 43.9 8.2 2.2e-09 36.4 1.2 2.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 AMK77262.1 - 1.5e-10 40.5 50.3 1.5e-10 40.5 50.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly PF00912.22 AMK77263.1 - 1.6e-65 219.9 0.2 3.4e-65 218.8 0.2 1.6 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 AMK77263.1 - 1e-32 113.6 0.0 2e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PCB_OB PF17092.5 AMK77263.1 - 6.2e-14 52.7 0.0 1.3e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain PilM_2 PF11104.8 AMK77264.1 - 2.2e-138 460.9 0.8 2.5e-138 460.8 0.8 1.0 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; FtsA PF14450.6 AMK77264.1 - 2.2e-11 44.1 0.2 2.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 AMK77264.1 - 4.8e-06 25.6 1.4 0.014 14.2 0.0 2.7 2 1 1 3 3 3 2 MreB/Mbl protein DDR PF08841.10 AMK77264.1 - 0.027 13.5 4.6 2.3 7.1 0.0 3.1 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain PilN PF05137.13 AMK77265.1 - 1.8e-20 72.8 0.0 3.3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) Mod_r PF07200.13 AMK77265.1 - 0.0049 17.0 0.1 0.0078 16.3 0.1 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Mid2 PF04478.12 AMK77265.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Vpu PF00558.19 AMK77265.1 - 0.054 13.3 3.6 0.056 13.2 2.5 1.6 1 1 0 1 1 1 0 Vpu protein PilO PF04350.13 AMK77266.1 - 3.1e-48 163.6 0.1 4.1e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Pilus assembly protein, PilO BLOC1_2 PF10046.9 AMK77266.1 - 0.0062 16.8 1.0 0.014 15.7 1.0 1.6 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Kri1 PF05178.12 AMK77266.1 - 0.11 13.1 0.9 0.16 12.5 0.9 1.2 1 0 0 1 1 1 0 KRI1-like family RRF_GI PF12614.8 AMK77266.1 - 0.14 12.3 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF5305 PF17231.2 AMK77266.1 - 0.14 11.5 0.2 0.14 11.5 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5305) PilP PF04351.13 AMK77267.1 - 1.6e-51 174.2 0.0 1.8e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Pilus assembly protein, PilP Secretin PF00263.21 AMK77268.1 - 1.1e-46 158.6 3.5 2.4e-46 157.5 3.5 1.6 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AMK77268.1 - 6.9e-14 52.0 0.3 4.4e-13 49.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial type II/III secretion system short domain AMIN PF11741.8 AMK77268.1 - 1.4e-10 41.2 0.7 1.1e-08 35.0 0.1 2.7 2 0 0 2 2 2 1 AMIN domain STN PF07660.14 AMK77268.1 - 6.9e-10 38.6 0.9 3.3e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain BMC PF00936.19 AMK77268.1 - 0.079 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 BMC domain Orn_Arg_deC_N PF02784.16 AMK77269.1 - 2.2e-71 240.2 0.0 2.7e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AMK77269.1 - 2e-27 95.3 0.0 2.6e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AMK77269.1 - 7.4e-05 22.5 0.0 0.00034 20.3 0.0 2.0 2 1 0 2 2 2 1 Alanine racemase, N-terminal domain DAP_epimerase PF01678.19 AMK77270.1 - 9.2e-59 196.9 0.4 2.9e-29 101.7 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AMK77270.1 - 1.9e-05 24.3 0.2 3.3e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Phenazine biosynthesis-like protein DUF484 PF04340.12 AMK77271.1 - 9.1e-50 169.4 0.3 1.1e-49 169.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 DUF3851 PF12962.7 AMK77271.1 - 0.033 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Tsi6 PF18660.1 AMK77271.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Tsi6 Phage_integrase PF00589.22 AMK77272.1 - 2.5e-49 167.4 0.0 4e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AMK77272.1 - 1.1e-19 70.5 1.8 1.1e-19 70.5 1.8 2.7 2 1 3 5 5 5 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AMK77272.1 - 2.7e-08 34.1 0.6 7.8e-08 32.7 0.6 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_2 PF12834.7 AMK77272.1 - 0.00015 22.4 0.6 0.00046 20.8 0.1 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal DUF3435 PF11917.8 AMK77272.1 - 0.00044 19.3 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Integrase_1 PF12835.7 AMK77272.1 - 0.0063 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase Phage_int_SAM_5 PF13102.6 AMK77272.1 - 0.017 15.4 0.4 0.048 14.0 0.4 1.7 1 0 0 1 1 1 0 Phage integrase SAM-like domain Phage_integr_3 PF16795.5 AMK77272.1 - 0.018 15.0 0.1 7.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Archaeal phage integrase Glutaredoxin PF00462.24 AMK77273.1 - 4.2e-20 71.7 0.0 5.3e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AMK77273.1 - 0.00096 19.5 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HTH_Tnp_1 PF01527.20 AMK77274.1 - 0.068 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase AmoC PF04896.12 AMK77275.1 - 2.9e-120 400.1 17.8 3.5e-120 399.8 17.8 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C AMO PF02461.16 AMK77276.1 - 7.5e-123 408.9 18.0 8.5e-123 408.7 18.0 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase Monooxygenase_B PF04744.12 AMK77277.1 - 3.8e-178 592.1 0.2 4.5e-178 591.9 0.2 1.0 1 0 0 1 1 1 1 Monooxygenase subunit B protein DUF4232 PF14016.6 AMK77277.1 - 0.018 15.2 0.3 0.033 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) CARDB PF07705.11 AMK77277.1 - 0.052 13.8 0.0 0.21 11.9 0.0 2.0 1 1 0 1 1 1 0 CARDB LPAM_1 PF08139.12 AMK77278.1 - 0.054 14.0 2.8 0.14 12.7 2.8 1.7 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site FHA PF00498.26 AMK77279.1 - 2.9e-07 30.7 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain T6SS_VasE PF05936.12 AMK77280.1 - 2.1e-154 514.4 0.0 2.3e-154 514.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DotU PF09850.9 AMK77281.1 - 8.9e-62 208.4 0.4 1.3e-61 207.9 0.4 1.3 1 0 0 1 1 1 1 Type VI secretion system protein DotU OmpA PF00691.20 AMK77281.1 - 7.7e-15 55.0 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 OmpA family PsbJ PF01788.17 AMK77281.1 - 0.24 11.3 0.9 0.46 10.4 0.9 1.4 1 0 0 1 1 1 0 PsbJ ImcF-related_N PF14331.6 AMK77282.1 - 1.8e-93 312.6 6.3 2.9e-93 312.0 6.3 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain IcmF-related PF06761.12 AMK77282.1 - 6.4e-66 222.9 1.4 6.4e-66 222.9 1.4 1.8 2 0 0 2 2 2 1 Intracellular multiplication and human macrophage-killing IcmF_C PF06744.12 AMK77282.1 - 1.7e-57 194.3 0.8 3.4e-57 193.3 0.8 1.5 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal AAA_33 PF13671.6 AMK77282.1 - 0.097 12.8 1.0 7.2 6.8 0.9 3.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AMK77282.1 - 0.13 12.3 0.0 0.61 10.2 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 AMK77282.1 - 0.55 10.5 1.9 2.3 8.4 0.4 2.6 2 1 0 3 3 3 0 AAA domain TagF_N PF09867.9 AMK77283.1 - 9.9e-47 158.4 0.1 1.9e-46 157.5 0.1 1.5 1 0 0 1 1 1 1 TagF N-terminal domain, Type VI secretion system-associated PP2C_2 PF13672.6 AMK77283.1 - 1.8e-12 47.3 2.4 3.3e-12 46.5 2.4 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AMK77283.1 - 0.00019 21.1 0.2 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 AMK77283.1 - 0.0011 19.0 0.7 0.002 18.1 0.7 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) ImpA_N PF06812.12 AMK77284.1 - 8e-32 109.8 0.0 1.5e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 ImpA, N-terminal, type VI secretion system Acid_phosphat_B PF03767.14 AMK77284.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) T6SS_VipA PF05591.12 AMK77285.1 - 2.2e-57 193.2 0.2 2.5e-57 193.0 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 VipB PF05943.12 AMK77286.1 - 1.4e-190 633.6 0.0 1.6e-190 633.3 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion protein, EvpB/VC_A0108, tail sheath T6SS_HCP PF05638.12 AMK77287.1 - 2.4e-27 95.9 0.2 3e-27 95.5 0.2 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ImpE PF07024.13 AMK77288.1 - 1.1e-46 157.9 0.0 1.8e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 ImpE protein TPR_19 PF14559.6 AMK77288.1 - 4.8e-08 33.4 6.1 2.2e-06 28.1 1.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK77288.1 - 0.00023 21.7 7.2 0.093 13.6 0.1 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 AMK77288.1 - 0.00045 20.8 3.5 0.31 11.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 AMK77288.1 - 0.024 14.6 1.3 0.15 12.1 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 AMK77288.1 - 0.036 14.4 0.2 0.036 14.4 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK77288.1 - 0.073 13.3 0.2 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 AMK77288.1 - 0.1 11.9 2.1 2.3 7.5 0.1 2.2 2 1 0 2 2 2 0 MalT-like TPR region TPR_2 PF07719.17 AMK77288.1 - 0.24 11.6 2.2 3 8.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GPW_gp25 PF04965.14 AMK77289.1 - 2.3e-24 85.0 0.0 3.1e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Gene 25-like lysozyme T6SS_TssF PF05947.12 AMK77290.1 - 4.6e-229 762.0 0.0 5.1e-229 761.8 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssF DUF2985 PF11204.8 AMK77290.1 - 0.068 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) T6SS_TssG PF06996.11 AMK77291.1 - 5.4e-106 354.2 0.0 6.2e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion, TssG AAA_2 PF07724.14 AMK77292.1 - 1.3e-38 132.8 0.0 3.9e-38 131.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AMK77292.1 - 4.8e-29 100.3 1.6 1.9e-28 98.4 0.7 2.3 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 AMK77292.1 - 6.5e-18 65.4 0.1 3.1e-09 37.4 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AMK77292.1 - 1.1e-13 51.1 0.0 5e-13 48.9 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AMK77292.1 - 2.9e-11 43.5 0.1 3.7e-08 33.5 0.0 3.1 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK77292.1 - 3.3e-10 40.6 3.7 5.2e-06 26.9 0.1 4.5 4 1 0 4 4 4 1 AAA ATPase domain Sigma54_activat PF00158.26 AMK77292.1 - 1.5e-06 28.0 0.1 0.00029 20.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 AMK77292.1 - 2.9e-06 27.6 3.1 0.029 14.6 0.0 4.5 3 1 0 4 4 4 2 AAA domain TniB PF05621.11 AMK77292.1 - 2.4e-05 23.9 0.0 0.39 10.1 0.0 3.9 4 1 0 5 5 5 2 Bacterial TniB protein AAA_7 PF12775.7 AMK77292.1 - 2.8e-05 23.7 0.1 0.13 11.8 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 AMK77292.1 - 0.00014 21.9 0.1 0.13 12.2 0.1 3.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 AMK77292.1 - 0.00018 21.1 0.4 0.2 11.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AMK77292.1 - 0.00022 21.2 0.3 0.042 13.8 0.0 3.2 2 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 AMK77292.1 - 0.00072 19.6 0.0 0.81 9.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 AMK77292.1 - 0.00077 18.8 2.0 0.0047 16.2 0.0 2.9 4 0 0 4 4 3 1 Zeta toxin ResIII PF04851.15 AMK77292.1 - 0.001 19.1 0.1 0.84 9.6 0.1 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 AMK77292.1 - 0.0015 18.3 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 AMK77292.1 - 0.0051 17.4 1.9 0.14 12.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 AMK77292.1 - 0.013 14.6 0.1 1.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein CbiA PF01656.23 AMK77292.1 - 0.013 15.6 0.2 0.078 13.0 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 AMK77292.1 - 0.015 15.3 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hpr_kinase_C PF07475.12 AMK77292.1 - 0.017 14.7 0.4 0.18 11.4 0.1 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 AMK77292.1 - 0.036 13.8 0.1 7.8 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK77292.1 - 0.043 13.7 0.1 14 5.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Torsin PF06309.11 AMK77292.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Torsin SRP54 PF00448.22 AMK77292.1 - 0.064 12.9 0.4 0.44 10.1 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AMK77292.1 - 0.079 12.7 0.0 5 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 AMK77292.1 - 0.084 12.8 1.5 8.8 6.2 0.1 3.0 3 0 0 3 3 3 0 NTPase ABC_tran_CTD PF16326.5 AMK77292.1 - 0.22 11.8 6.8 0.1 12.9 1.6 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA_19 PF13245.6 AMK77292.1 - 0.95 9.8 3.0 18 5.6 0.7 3.1 2 1 0 2 2 2 0 AAA domain Peptidase_C42 PF05533.12 AMK77294.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 PAAR_motif PF05488.13 AMK77296.1 - 7.7e-29 99.7 15.5 4.9e-25 87.5 9.0 2.8 1 1 2 3 3 3 3 PAAR motif DUF4150 PF13665.6 AMK77296.1 - 0.0003 20.9 0.3 0.3 11.2 0.0 2.9 1 1 1 3 3 3 2 Domain of unknown function (DUF4150) Phage_GPD PF05954.11 AMK77297.1 - 8.2e-92 307.7 1.7 8.4e-92 307.7 0.6 1.6 2 0 0 2 2 2 1 Phage late control gene D protein (GPD) Sarcoglycan_1 PF04790.13 AMK77297.1 - 0.022 14.1 3.5 0.037 13.4 3.2 1.5 1 1 0 1 1 1 0 Sarcoglycan complex subunit protein DUF2345 PF10106.9 AMK77297.1 - 0.064 13.1 0.5 0.28 11.1 1.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Cu_amine_oxidN1 PF07833.11 AMK77297.1 - 0.13 12.8 2.9 5.2 7.6 2.3 3.1 2 1 0 2 2 2 0 Copper amine oxidase N-terminal domain DUF4397 PF14344.6 AMK77297.1 - 0.23 12.2 3.6 0.43 11.4 1.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4397) DUF2341 PF10102.9 AMK77297.1 - 0.63 10.7 3.0 37 5.0 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2341) Gp5_C PF06715.12 AMK77297.1 - 1 9.6 12.4 0.061 13.5 2.3 3.8 3 1 1 4 4 4 0 Gp5 C-terminal repeat (3 copies) DUF2185 PF09951.9 AMK77298.1 - 1.9e-05 24.4 0.1 3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) HEAT_2 PF13646.6 AMK77299.1 - 0.038 14.4 0.0 0.29 11.6 0.0 1.9 1 1 0 1 1 1 0 HEAT repeats Imm-NTF2 PF15655.6 AMK77300.1 - 1.3e-25 90.2 4.3 1.4e-25 90.0 4.3 1.0 1 0 0 1 1 1 1 NTF2 fold immunity protein MCRS_N PF13325.6 AMK77300.1 - 0.035 14.1 0.3 0.078 13.0 0.1 1.6 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein SMI1_KNR4 PF09346.10 AMK77301.1 - 1.2e-14 54.8 0.1 1.6e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 AMK77301.1 - 7.8e-12 45.7 0.1 9.8e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 AMK77301.1 - 3.1e-06 27.0 0.1 4.7e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall RHS PF03527.14 AMK77303.1 - 7.6e-13 48.0 1.2 1.4e-12 47.1 1.2 1.4 1 0 0 1 1 1 1 RHS protein RHS_repeat PF05593.14 AMK77303.1 - 0.00097 19.6 4.7 0.67 10.5 0.1 2.8 2 1 0 2 2 2 2 RHS Repeat Fe-ADH PF00465.19 AMK77304.1 - 4.3e-94 315.3 0.0 5.1e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AMK77304.1 - 2.5e-14 53.6 0.0 2e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase FAD-SLDH PF12318.8 AMK77304.1 - 0.0086 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase ABM PF03992.16 AMK77305.1 - 1.8e-09 37.5 0.3 2.2e-09 37.3 0.3 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PP_kinase PF02503.17 AMK77305.1 - 0.085 12.4 0.0 0.094 12.3 0.0 1.0 1 0 0 1 1 1 0 Polyphosphate kinase middle domain T6SS-SciN PF12790.7 AMK77306.1 - 5e-36 123.1 0.1 5.9e-36 122.8 0.1 1.1 1 0 0 1 1 1 1 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Ca_hom_mod PF14798.6 AMK77307.1 - 0.0086 15.2 0.1 0.01 14.9 0.1 1.0 1 0 0 1 1 1 1 Calcium homeostasis modulator Metal_resist PF13801.6 AMK77307.1 - 0.046 13.9 0.0 0.05 13.8 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance C1_2 PF03107.16 AMK77307.1 - 0.077 13.3 1.1 0.12 12.7 1.1 1.3 1 0 0 1 1 1 0 C1 domain zf-ribbon_3 PF13248.6 AMK77307.1 - 0.094 12.2 8.6 2.3 7.8 8.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 AMK77307.1 - 0.18 12.0 2.6 0.34 11.1 2.6 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 AMK77307.1 - 0.38 10.7 1.7 0.8 9.7 1.7 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 AMK77307.1 - 0.38 10.9 4.1 7.6 6.7 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain UPF0547 PF10571.9 AMK77307.1 - 0.63 10.2 8.4 3.6 7.8 2.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Rubredoxin PF00301.20 AMK77307.1 - 1.7 8.7 5.6 2.6 8.1 0.4 2.5 1 1 1 2 2 2 0 Rubredoxin zf-C2H2_4 PF13894.6 AMK77307.1 - 2.5 9.2 4.8 11 7.2 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger CpXC PF14353.6 AMK77307.1 - 3.1 7.9 6.4 79 3.3 6.4 2.2 1 1 0 1 1 1 0 CpXC protein zf-ACC PF17848.1 AMK77307.1 - 3.1 7.9 7.4 17 5.6 0.4 2.6 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Peptidase_M3 PF01432.20 AMK77308.1 - 1.3e-156 522.5 0.9 1.3e-156 522.5 0.9 2.0 2 0 0 2 2 2 1 Peptidase family M3 DUF3631 PF12307.8 AMK77308.1 - 0.38 11.0 4.1 1.4 9.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3631) HDOD PF08668.12 AMK77309.1 - 7.6e-33 113.6 0.0 1.1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 HDOD domain cNMP_binding PF00027.29 AMK77309.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NAD1 PF18778.1 AMK77309.1 - 0.0054 16.8 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 AMK77309.1 - 0.068 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 HDOD PF08668.12 AMK77310.1 - 1e-37 129.5 0.2 1.9e-37 128.6 0.2 1.4 1 1 0 1 1 1 1 HDOD domain cNMP_binding PF00027.29 AMK77310.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HDOD PF08668.12 AMK77311.1 - 7.1e-33 113.7 0.0 1.4e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 HDOD domain cNMP_binding PF00027.29 AMK77311.1 - 3.5e-05 23.8 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 AMK77311.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pirin PF02678.16 AMK77311.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Pirin Shikimate_dh_N PF08501.11 AMK77312.1 - 1.7e-24 85.9 0.0 2.6e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AMK77312.1 - 8e-11 41.5 0.2 1.7e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AMK77312.1 - 1.2e-10 41.5 0.0 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 AMK77312.1 - 0.00031 21.0 0.0 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Mntp PF02659.15 AMK77313.1 - 0.075 12.8 5.8 0.3 10.8 5.7 2.1 1 1 0 1 1 1 0 Putative manganese efflux pump DUF3792 PF12670.7 AMK77313.1 - 0.081 13.1 15.1 1.3 9.2 7.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) SLATT_1 PF18181.1 AMK77313.1 - 0.14 12.1 4.5 7.5 6.5 1.0 2.5 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1430 PF07242.11 AMK77313.1 - 0.55 10.5 0.0 0.55 10.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1430) TctB PF07331.11 AMK77313.1 - 2.4 8.4 17.9 1.6e+02 2.6 19.3 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.6 AMK77313.1 - 2.7 7.6 13.2 1.9 8.1 0.6 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) YtpI PF14007.6 AMK77313.1 - 5.6 7.2 9.3 0.19 11.9 0.5 2.6 2 1 1 3 3 3 0 YtpI-like protein ALAD PF00490.21 AMK77314.1 - 5.9e-142 472.5 0.0 6.6e-142 472.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MlaC PF05494.12 AMK77315.1 - 1.3e-46 158.4 0.2 1.5e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 MlaC protein HMG_box PF00505.19 AMK77315.1 - 0.078 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box T3SS_needle_E PF08988.10 AMK77315.1 - 0.15 12.2 0.1 0.39 10.9 0.1 1.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Methyltransf_25 PF13649.6 AMK77316.1 - 6.1e-14 52.5 0.1 1.3e-13 51.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77316.1 - 6.7e-14 52.3 0.1 1.1e-13 51.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK77316.1 - 7.7e-09 35.5 0.3 9.8e-09 35.2 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77316.1 - 7.2e-08 33.1 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK77316.1 - 3.7e-07 29.7 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AMK77316.1 - 2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AMK77316.1 - 0.00046 19.9 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 AMK77316.1 - 0.00091 18.8 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 AMK77316.1 - 0.00094 18.5 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 AMK77316.1 - 0.017 14.8 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 AMK77316.1 - 0.032 14.2 0.4 0.051 13.5 0.4 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 AMK77316.1 - 0.046 13.6 1.5 0.62 9.9 1.5 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 AMK77316.1 - 0.065 12.7 0.6 0.51 9.8 0.3 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_7 PF03492.15 AMK77316.1 - 0.069 12.4 0.1 0.55 9.4 0.1 2.0 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Methyltransf_4 PF02390.17 AMK77316.1 - 0.17 11.3 0.3 0.45 10.0 0.2 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.11 AMK77317.1 - 7e-139 462.1 0.0 8e-139 461.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 AMK77317.1 - 8.1e-11 42.0 0.0 2.2e-10 40.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77317.1 - 1.3e-10 41.8 0.0 8.4e-09 36.0 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK77317.1 - 5.2e-10 39.9 0.0 2.9e-08 34.3 0.0 3.1 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK77317.1 - 1e-09 38.4 0.0 3.4e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77317.1 - 8.7e-05 23.2 0.0 0.00052 20.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain PDDEXK_6 PF04720.12 AMK77317.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function CMAS PF02353.20 AMK77317.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.16 AMK77317.1 - 0.27 10.3 0.0 0.71 8.9 0.0 1.6 2 0 0 2 2 2 0 mRNA capping enzyme HHH_3 PF12836.7 AMK77318.1 - 3.5e-21 75.2 0.1 4.1e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 AMK77318.1 - 8.9e-11 41.1 0.0 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 AMK77318.1 - 4.1e-07 30.5 0.1 0.012 16.2 0.0 2.2 2 0 0 2 2 2 2 Helix-hairpin-helix domain T2SSK PF03934.13 AMK77318.1 - 0.00066 19.1 0.0 0.00079 18.9 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 AMK77318.1 - 0.00087 19.5 0.0 0.0017 18.6 0.0 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 AMK77318.1 - 0.014 15.5 0.1 1.7 8.8 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif HHH_8 PF14716.6 AMK77318.1 - 0.033 14.6 0.2 2.5 8.5 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 AMK77318.1 - 0.05 13.9 0.0 3.7 8.1 0.0 2.3 2 0 0 2 2 2 0 IMS family HHH motif DUF655 PF04919.12 AMK77318.1 - 0.096 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF655) MIF PF01187.18 AMK77319.1 - 8.7e-25 87.2 0.0 9.7e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase_2 PF14552.6 AMK77319.1 - 2e-06 27.8 0.0 0.0053 16.8 0.0 2.0 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase PF01361.21 AMK77319.1 - 0.014 15.3 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme LigT_PEase PF02834.16 AMK77320.1 - 1.9e-14 53.6 0.0 1.9e-07 31.2 0.0 2.7 2 1 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AMK77320.1 - 8.2e-08 32.3 0.0 9.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MBA1 PF07961.11 AMK77320.1 - 0.054 12.5 0.1 0.069 12.2 0.1 1.1 1 0 0 1 1 1 0 MBA1-like protein OMPdecase PF00215.24 AMK77321.1 - 3e-30 105.5 2.3 3.4e-30 105.3 2.3 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim PF00834.19 AMK77321.1 - 3.3e-07 29.9 2.6 1.2e-06 28.1 2.6 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AMK77321.1 - 5.3e-05 23.1 0.3 0.00065 19.5 0.3 2.1 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PALP PF00291.25 AMK77321.1 - 0.001 18.5 1.5 0.24 10.8 0.2 2.3 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme IGPS PF00218.21 AMK77321.1 - 0.0067 15.6 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase HMGL-like PF00682.19 AMK77321.1 - 0.011 15.3 0.4 0.034 13.7 0.2 1.8 1 1 1 2 2 2 0 HMGL-like PcrB PF01884.17 AMK77321.1 - 0.021 14.3 2.2 0.032 13.7 2.1 1.3 1 1 0 1 1 1 0 PcrB family PEP_mutase PF13714.6 AMK77321.1 - 0.091 12.2 4.3 2 7.8 0.6 2.2 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase TMP-TENI PF02581.17 AMK77321.1 - 0.17 11.2 7.3 0.06 12.7 2.5 2.1 1 1 1 2 2 2 0 Thiamine monophosphate synthase SIS PF01380.22 AMK77322.1 - 1.6e-19 70.0 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 AMK77322.1 - 1.2e-07 31.9 0.5 5e-06 26.6 0.1 2.2 1 1 1 2 2 2 1 SIS domain DUF2529 PF10740.9 AMK77322.1 - 0.053 13.2 0.0 0.077 12.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2529) Transketolase_N PF00456.21 AMK77323.1 - 3.5e-161 535.7 0.0 4.9e-161 535.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AMK77323.1 - 9.3e-47 159.0 0.0 1.7e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AMK77323.1 - 3.4e-14 52.8 0.0 7.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AMK77323.1 - 4.2e-08 32.7 0.0 0.00021 20.6 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AMK77323.1 - 1.3e-05 24.3 0.0 0.00065 18.7 0.0 2.2 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AMK77323.1 - 0.0023 17.7 0.1 0.0075 16.1 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain BMC PF00936.19 AMK77323.1 - 0.077 13.0 0.2 0.95 9.5 0.0 2.5 2 0 0 2 2 2 0 BMC domain DUF456 PF04306.13 AMK77324.1 - 0.2 11.9 0.3 0.39 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF456) TAL_FSA PF00923.19 AMK77325.1 - 9.4e-94 314.0 0.2 1.1e-93 313.8 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GOLGA2L5 PF15070.6 AMK77325.1 - 0.014 14.1 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 F_bP_aldolase PF01116.20 AMK77326.1 - 5.4e-87 291.8 0.1 6e-87 291.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.6 AMK77326.1 - 0.12 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Enolase C-terminal domain-like FliL PF03748.14 AMK77327.1 - 1.2e-19 70.8 0.0 1.2e-19 70.8 0.0 1.7 3 0 0 3 3 3 1 Flagellar basal body-associated protein FliL DUF4366 PF14283.6 AMK77327.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) FliM PF02154.15 AMK77328.1 - 1.8e-75 253.1 1.0 2.5e-75 252.6 1.0 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 AMK77328.1 - 3.5e-17 62.2 0.7 6.7e-17 61.3 0.7 1.4 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliMN_C PF01052.20 AMK77329.1 - 1.1e-24 86.1 1.7 1.5e-24 85.8 1.7 1.2 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliN_N PF16973.5 AMK77329.1 - 1.9 8.4 20.3 1.5 8.7 6.4 3.0 1 1 2 3 3 3 0 Flagellar motor switch protein FliN N-terminal FliO PF04347.13 AMK77330.1 - 2.3e-15 56.7 1.1 3.9e-15 55.9 1.1 1.4 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO FliP PF00813.20 AMK77331.1 - 5.9e-79 264.4 18.5 8.1e-79 264.0 18.5 1.2 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 AMK77332.1 - 1.1e-26 92.6 10.7 1.2e-26 92.4 10.7 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 DUF5357 PF17310.2 AMK77332.1 - 0.071 11.7 1.8 0.077 11.5 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5357) ATP-synt_J PF04911.12 AMK77332.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase j chain TM_helix PF05552.12 AMK77332.1 - 0.36 10.8 5.3 0.89 9.6 3.0 2.6 2 1 0 2 2 2 0 Conserved TM helix Bac_export_2 PF01312.19 AMK77332.1 - 0.68 9.1 4.7 0.8 8.8 1.7 1.8 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Bac_export_1 PF01311.20 AMK77333.1 - 4.8e-64 216.1 32.0 5.4e-64 215.9 32.0 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 AMK77334.1 - 5.2e-119 397.3 0.7 5.9e-119 397.1 0.7 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family FliP PF00813.20 AMK77334.1 - 0.018 15.0 0.7 0.076 12.9 0.1 2.0 2 0 0 2 2 2 0 FliP family Phage_Gp23 PF10669.9 AMK77334.1 - 0.32 11.3 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) FHIPEP PF00771.20 AMK77335.1 - 8.7e-272 903.4 5.1 1e-271 903.2 5.1 1.0 1 0 0 1 1 1 1 FHIPEP family Asp4 PF16996.5 AMK77335.1 - 6.1 6.7 6.4 0.64 9.8 1.3 2.1 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 SRP54 PF00448.22 AMK77336.1 - 1.5e-37 129.1 0.3 3e-37 128.2 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 AMK77336.1 - 4.8e-05 23.7 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK77336.1 - 0.00016 21.7 0.1 0.0022 18.0 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 AMK77336.1 - 0.00038 20.1 1.7 0.013 15.0 0.5 2.6 1 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 AMK77336.1 - 0.00047 20.2 0.1 0.0018 18.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 AMK77336.1 - 0.0018 18.8 0.7 0.0055 17.2 0.1 2.1 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 AMK77336.1 - 0.0027 17.5 0.1 0.0069 16.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AMK77336.1 - 0.0029 17.8 0.3 0.29 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 AMK77336.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.17 AMK77336.1 - 0.007 16.5 2.3 0.017 15.2 0.9 2.2 2 1 0 2 2 2 1 Helicase HerA, central domain ResIII PF04851.15 AMK77336.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 AMK77336.1 - 0.016 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AMK77336.1 - 0.026 14.5 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AMK77336.1 - 0.031 14.6 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 AMK77336.1 - 0.034 14.1 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 AMK77336.1 - 0.038 13.6 1.1 0.099 12.2 0.4 2.1 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mrr_cat PF04471.12 AMK77336.1 - 0.12 12.5 0.3 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 Restriction endonuclease AAA PF00004.29 AMK77336.1 - 0.12 12.8 0.2 0.34 11.3 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 AMK77336.1 - 0.14 12.5 1.7 0.44 10.9 1.6 2.1 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AMK77336.1 - 0.15 12.0 0.7 1.9 8.5 0.7 2.4 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ParA PF10609.9 AMK77337.1 - 2.6e-21 76.2 3.8 9e-21 74.4 3.8 1.7 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AMK77337.1 - 4.4e-18 65.6 0.1 1.8e-17 63.6 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AMK77337.1 - 1.3e-17 64.3 0.1 3e-17 63.1 0.1 1.6 1 1 1 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 AMK77337.1 - 6.7e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 AMK77337.1 - 7.2e-09 35.5 2.4 8.4e-08 32.0 2.4 2.6 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 AMK77337.1 - 6.7e-08 32.1 0.5 1.5e-07 31.0 0.5 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 AMK77337.1 - 6.3e-07 28.9 2.8 6.2e-06 25.6 0.6 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_24 PF13479.6 AMK77337.1 - 0.0021 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain VirC1 PF07015.11 AMK77337.1 - 0.0064 15.8 0.6 0.016 14.5 0.1 1.8 2 0 0 2 2 2 1 VirC1 protein AAA_26 PF13500.6 AMK77337.1 - 0.0067 16.3 0.9 0.044 13.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain SIS_2 PF13580.6 AMK77337.1 - 0.084 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 SIS domain MeaB PF03308.16 AMK77337.1 - 0.091 11.7 3.5 0.28 10.1 0.3 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 AMK77337.1 - 0.1 12.3 1.0 1.1 9.0 0.1 2.4 2 1 0 2 2 2 0 IstB-like ATP binding protein PelD_GGDEF PF16963.5 AMK77337.1 - 0.19 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 PelD GGDEF domain SRP54 PF00448.22 AMK77337.1 - 0.26 10.9 1.7 13 5.4 0.1 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma70_r4 PF04545.16 AMK77338.1 - 1.5e-18 66.0 0.8 2.9e-18 65.1 0.8 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK77338.1 - 3.5e-18 65.1 0.0 9.2e-18 63.8 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 AMK77338.1 - 9.3e-11 41.7 0.5 2.6e-09 37.0 0.1 2.4 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 AMK77338.1 - 2.2e-08 33.6 1.2 4.8e-08 32.6 1.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AMK77338.1 - 0.00049 19.8 1.7 0.0029 17.4 0.1 2.7 2 1 1 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 AMK77338.1 - 0.0016 18.1 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0122 PF04297.14 AMK77338.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_10 PF04967.12 AMK77338.1 - 0.053 13.3 0.0 5.3 6.9 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain Phage_GPL PF05926.11 AMK77338.1 - 0.1 12.6 0.1 9.3 6.2 0.0 2.8 3 0 0 3 3 3 0 Phage head completion protein (GPL) DUF1548 PF07579.11 AMK77338.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Phage_terminase PF10668.9 AMK77338.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit Response_reg PF00072.24 AMK77339.1 - 1.3e-29 102.6 0.1 1.5e-29 102.4 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Glycos_transf_1 PF00534.20 AMK77339.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 CheZ PF04344.13 AMK77340.1 - 1.2e-67 227.8 0.4 1.6e-67 227.4 0.4 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ CorA PF01544.18 AMK77340.1 - 0.15 11.4 1.4 0.17 11.2 0.5 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CheW PF01584.19 AMK77341.1 - 5.3e-24 84.4 0.1 1.1e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AMK77341.1 - 1.1e-17 64.0 1.9 3.1e-17 62.6 0.0 2.7 3 0 0 3 3 3 1 Hpt domain HATPase_c PF02518.26 AMK77341.1 - 3.1e-17 63.1 0.1 8.6e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AMK77341.1 - 8.6e-12 45.3 2.6 2.6e-11 43.8 2.6 1.9 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain SHOCT PF09851.9 AMK77341.1 - 0.0011 18.7 10.2 1.1 9.1 0.1 3.7 3 0 0 3 3 3 3 Short C-terminal domain HATPase_c_3 PF13589.6 AMK77341.1 - 0.0016 18.3 0.1 0.0042 16.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fes1 PF08609.10 AMK77341.1 - 1.3 9.9 4.1 1.1 10.2 0.2 2.9 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 CheB_methylest PF01339.17 AMK77342.1 - 9.2e-56 188.2 0.8 2e-55 187.1 0.2 1.7 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AMK77342.1 - 1.6e-23 83.0 0.7 3.5e-23 81.9 0.7 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DXP_reductoisom PF02670.16 AMK77342.1 - 0.03 15.0 0.0 0.089 13.5 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase MotA_ExbB PF01618.16 AMK77343.1 - 7.2e-30 103.4 0.4 1.1e-29 102.7 0.4 1.3 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family LPG_synthase_TM PF03706.13 AMK77343.1 - 0.0051 16.4 4.3 0.018 14.6 1.0 2.0 2 0 0 2 2 2 2 Lysylphosphatidylglycerol synthase TM region MacB_PCD PF12704.7 AMK77343.1 - 0.68 10.2 2.5 0.5 10.7 0.1 2.0 2 0 0 2 2 2 0 MacB-like periplasmic core domain MotB_plug PF13677.6 AMK77344.1 - 7.1e-22 76.8 0.1 7.1e-22 76.8 0.1 1.9 3 0 0 3 3 3 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 AMK77344.1 - 1.9e-20 73.0 0.0 3.6e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 OmpA family AAA_31 PF13614.6 AMK77345.1 - 5.3e-44 150.2 0.0 6.8e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK77345.1 - 1.7e-20 73.4 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 AMK77345.1 - 1.8e-09 37.2 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 AMK77345.1 - 2.2e-09 37.2 0.0 4.7e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 AMK77345.1 - 1.5e-08 34.5 0.2 1e-07 31.7 0.2 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AMK77345.1 - 4.1e-07 29.5 0.1 0.01 15.2 0.0 2.1 2 0 0 2 2 2 2 ATPase MipZ VirC1 PF07015.11 AMK77345.1 - 0.0077 15.6 0.0 0.07 12.4 0.0 2.1 2 0 0 2 2 2 1 VirC1 protein Fer4_NifH PF00142.18 AMK77345.1 - 0.012 15.1 0.0 0.064 12.7 0.0 2.0 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CheW PF01584.19 AMK77346.1 - 5.5e-11 42.3 0.0 9.3e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 CheW-like domain CheW PF01584.19 AMK77347.1 - 1.7e-39 134.6 0.5 1.9e-39 134.5 0.5 1.0 1 0 0 1 1 1 1 CheW-like domain DUF2802 PF10975.8 AMK77348.1 - 1.6e-14 53.7 0.7 1.1e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) Baculo_11_kDa PF06143.11 AMK77348.1 - 0.0095 15.5 0.3 0.018 14.6 0.3 1.5 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF4446 PF14584.6 AMK77348.1 - 0.017 15.1 0.4 0.023 14.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) KxDL PF10241.9 AMK77348.1 - 0.056 13.7 0.4 0.077 13.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF948 PF06103.11 AMK77348.1 - 0.061 13.6 1.8 0.096 13.0 1.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Vpu PF00558.19 AMK77348.1 - 0.081 12.7 0.5 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Vpu protein DUF4381 PF14316.6 AMK77348.1 - 0.085 13.1 0.8 0.11 12.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Asp5 PF17000.5 AMK77348.1 - 0.22 11.7 3.6 0.34 11.1 3.6 1.3 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 Glycos_transf_2 PF00535.26 AMK77349.1 - 1.7e-20 73.5 0.0 3.4e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK77349.1 - 3.5e-15 56.2 0.0 3.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 AMK77349.1 - 6.2e-15 54.6 0.2 1.2e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 AMK77349.1 - 1.7e-09 37.9 0.0 2.2e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 CHGN PF05679.16 AMK77349.1 - 0.015 14.2 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Glycos_transf_2 PF00535.26 AMK77350.1 - 8e-19 68.1 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AMK77350.1 - 2.1e-07 31.4 0.3 9e-07 29.3 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK77350.1 - 1.5e-06 28.3 0.0 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Wzy_C PF04932.15 AMK77351.1 - 4.4e-24 84.9 4.9 4.4e-24 84.9 4.9 3.7 1 1 2 3 3 3 2 O-Antigen ligase Glyco_transf_25 PF01755.17 AMK77352.1 - 1.1e-07 31.9 0.0 3.4e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_9 PF01075.17 AMK77353.1 - 1.2e-29 103.4 0.0 2.1e-29 102.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) ABC_membrane PF00664.23 AMK77354.1 - 1.7e-47 162.4 7.2 2.5e-47 161.8 7.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AMK77354.1 - 1.5e-33 116.2 0.1 3e-33 115.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AMK77354.1 - 5e-07 29.4 0.3 1.2e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AMK77354.1 - 0.00018 21.9 0.1 0.00036 21.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AMK77354.1 - 0.00076 19.4 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AMK77354.1 - 0.019 14.7 0.1 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AMK77354.1 - 0.021 15.1 0.2 0.14 12.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AMK77354.1 - 0.023 14.4 1.6 0.12 12.0 1.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AMK77354.1 - 0.05 13.8 0.6 1.4 9.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AMK77354.1 - 0.073 13.2 0.4 0.36 10.9 0.4 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 AMK77354.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) YwiC PF14256.6 AMK77354.1 - 1.9 8.8 7.0 1.1 9.5 0.1 2.7 3 0 0 3 3 3 0 YwiC-like protein Radical_SAM PF04055.21 AMK77355.1 - 9.5e-24 84.6 0.0 1.8e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AMK77355.1 - 2.1e-08 34.5 0.6 4.9e-08 33.4 0.6 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AMK77355.1 - 1.8e-07 31.5 0.0 4.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AMK77355.1 - 1.1e-05 25.5 0.0 2.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain HMGL-like PF00682.19 AMK77355.1 - 0.022 14.3 0.0 0.063 12.8 0.0 1.6 1 1 0 1 1 1 0 HMGL-like AP_endonuc_2 PF01261.24 AMK77355.1 - 0.073 12.5 0.0 0.6 9.5 0.1 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF4279 PF14106.6 AMK77355.1 - 0.1 12.8 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) PqqD PF05402.12 AMK77356.1 - 1.2e-14 54.3 0.1 1.5e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Uma2 PF05685.12 AMK77357.1 - 5e-35 120.6 0.0 5.9e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease TENA_THI-4 PF03070.16 AMK77358.1 - 4.9e-57 193.1 0.1 5.6e-57 192.9 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Ecotin PF03974.13 AMK77358.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Ecotin Glutaredoxin2_C PF04399.13 AMK77358.1 - 0.066 13.0 0.3 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Lactamase_B_2 PF12706.7 AMK77359.1 - 8.5e-47 159.3 0.1 1e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TauE PF01925.19 AMK77360.1 - 5.6e-57 193.1 27.6 6.3e-57 192.9 27.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE PolyA_pol PF01743.20 AMK77361.1 - 4.6e-17 62.6 0.0 1.4e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AMK77361.1 - 1.3e-10 40.9 0.0 3.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 AMK77361.1 - 5.3e-10 39.6 0.6 5.3e-10 39.6 0.6 2.1 2 0 0 2 2 2 1 HD domain DMT_6 PF04342.12 AMK77362.1 - 1.8e-46 156.6 5.3 2.1e-46 156.4 5.3 1.0 1 0 0 1 1 1 1 Putative member of DMT superfamily (DUF486) DUF1772 PF08592.11 AMK77362.1 - 1.3 9.4 6.6 8.3 6.7 6.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) RsmJ PF04378.13 AMK77363.1 - 4.3e-96 320.9 0.0 5e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ RNA_Me_trans PF04252.13 AMK77363.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Cons_hypoth95 PF03602.15 AMK77363.1 - 0.18 11.4 0.0 0.99 9.0 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical protein 95 COE1_HLH PF16423.5 AMK77364.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain PmbA_TldD PF01523.16 AMK77365.1 - 2.4e-70 237.6 0.1 4.1e-70 236.8 0.1 1.4 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 AMK77366.1 - 4.9e-61 207.0 0.3 6.8e-61 206.6 0.3 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DHO_dh PF01180.21 AMK77367.1 - 1.9e-94 316.2 0.2 2.5e-94 315.8 0.2 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 AMK77367.1 - 2.6e-05 23.8 1.4 4.5e-05 23.0 1.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 AMK77367.1 - 0.00041 19.5 0.0 0.0011 18.1 0.1 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 AMK77367.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DAO PF01266.24 AMK77368.1 - 2.4e-59 201.7 0.0 2.7e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK77368.1 - 4.7e-15 55.6 0.0 7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 AMK77368.1 - 9e-09 35.0 0.0 4.2e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AMK77368.1 - 5.9e-08 31.8 1.3 0.0001 21.2 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 AMK77368.1 - 2.2e-07 31.0 0.1 9.9e-07 28.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AMK77368.1 - 4.6e-07 29.4 0.2 0.01 15.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AMK77368.1 - 6.3e-06 25.7 1.2 4.2e-05 23.0 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 AMK77368.1 - 5.2e-05 23.7 0.1 0.04 14.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AMK77368.1 - 0.00076 18.9 0.1 0.068 12.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AMK77368.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 AMK77368.1 - 0.0027 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 AMK77368.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 AMK77368.1 - 0.027 13.5 0.0 0.71 8.8 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 AMK77368.1 - 0.047 13.0 0.1 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MCRA PF06100.11 AMK77368.1 - 0.054 12.3 0.4 4.3 6.0 0.0 2.1 2 0 0 2 2 2 0 MCRA family GIDA PF01134.22 AMK77368.1 - 0.092 11.8 0.1 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 AMK77368.1 - 0.094 12.7 1.5 0.81 9.7 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 AMK77368.1 - 0.098 11.5 0.1 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase OMP_b-brl_2 PF13568.6 AMK77369.1 - 0.0011 19.0 0.5 0.0027 17.8 0.5 1.7 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain JAKMIP_CC3 PF16034.5 AMK77369.1 - 0.0024 17.8 1.0 0.0034 17.4 1.0 1.1 1 0 0 1 1 1 1 JAKMIP CC3 domain DUF948 PF06103.11 AMK77369.1 - 0.0054 17.0 2.4 0.011 16.0 2.4 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 AMK77369.1 - 0.0075 16.7 1.0 0.013 16.0 1.0 1.3 1 0 0 1 1 1 1 Cell division protein ZapB THOC7 PF05615.13 AMK77369.1 - 0.019 15.2 2.2 0.028 14.7 2.2 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 CENP-F_leu_zip PF10473.9 AMK77369.1 - 0.023 14.7 0.8 0.034 14.2 0.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Opacity PF02462.15 AMK77369.1 - 0.029 14.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 Opacity family porin protein BLOC1_2 PF10046.9 AMK77369.1 - 0.034 14.4 1.6 0.058 13.7 1.6 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 AMK77369.1 - 0.036 13.4 11.1 0.051 12.9 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AIP3 PF03915.13 AMK77369.1 - 0.061 12.4 1.6 0.081 12.0 1.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 FH2 PF02181.23 AMK77369.1 - 0.071 12.2 1.9 0.098 11.8 1.9 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain ABC_tran_CTD PF16326.5 AMK77369.1 - 0.12 12.6 3.1 0.21 11.9 3.1 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain YabA PF06156.13 AMK77369.1 - 0.17 12.5 0.4 0.28 11.8 0.4 1.2 1 0 0 1 1 1 0 Initiation control protein YabA YlqD PF11068.8 AMK77369.1 - 0.32 11.4 4.0 0.48 10.8 4.0 1.2 1 0 0 1 1 1 0 YlqD protein OmpH PF03938.14 AMK77369.1 - 0.37 11.1 7.4 0.58 10.5 7.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) COG7 PF10191.9 AMK77369.1 - 0.51 8.5 5.0 0.66 8.1 5.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) CheZ PF04344.13 AMK77369.1 - 1.1 9.1 7.2 1.6 8.6 7.2 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ MerR-DNA-bind PF09278.11 AMK77369.1 - 2.8 8.5 6.3 6.2 7.4 4.5 2.1 1 1 1 2 2 2 0 MerR, DNA binding Abhydrolase_1 PF00561.20 AMK77370.1 - 2.7e-30 105.9 0.0 4.3e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AMK77370.1 - 1.1e-15 57.5 0.0 3.4e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AMK77370.1 - 2.5e-12 47.9 0.2 3.4e-12 47.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AMK77370.1 - 3.6e-05 23.3 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 AMK77370.1 - 7.7e-05 21.7 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 AMK77370.1 - 0.00089 18.9 0.0 0.0016 18.1 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 AMK77370.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 AMK77370.1 - 0.027 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.16 AMK77370.1 - 0.066 13.0 0.0 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 AMK77370.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 AMK77370.1 - 0.15 11.9 0.0 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Flavoprotein PF02441.19 AMK77371.1 - 4.9e-24 84.9 0.0 6.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Ntox8 PF15545.6 AMK77371.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 8 OMPdecase PF00215.24 AMK77372.1 - 1.1e-29 103.7 1.8 1.3e-29 103.4 1.8 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim PF00834.19 AMK77372.1 - 6.8e-08 32.1 2.1 3.2e-07 29.9 2.1 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 AMK77372.1 - 2.9e-05 23.9 0.2 0.00066 19.5 0.4 2.2 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PALP PF00291.25 AMK77372.1 - 0.0022 17.5 1.1 0.45 9.9 0.2 2.3 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme IGPS PF00218.21 AMK77372.1 - 0.0061 15.8 0.2 0.013 14.7 0.2 1.4 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase HMGL-like PF00682.19 AMK77372.1 - 0.0062 16.1 0.2 0.036 13.6 0.2 1.9 1 1 1 2 2 2 1 HMGL-like PEP_mutase PF13714.6 AMK77372.1 - 0.012 15.1 4.2 0.18 11.2 0.6 2.2 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase PcrB PF01884.17 AMK77372.1 - 0.016 14.6 1.6 0.021 14.3 1.6 1.3 1 0 0 1 1 1 0 PcrB family TMP-TENI PF02581.17 AMK77372.1 - 0.12 11.7 6.5 0.072 12.4 3.1 2.1 1 1 1 2 2 2 0 Thiamine monophosphate synthase Transketolase_N PF00456.21 AMK77373.1 - 2e-161 536.5 0.0 2.8e-161 536.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AMK77373.1 - 1.4e-46 158.4 0.0 2.5e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AMK77373.1 - 3.5e-14 52.8 0.0 7.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AMK77373.1 - 6.8e-08 32.0 0.0 0.00038 19.8 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 AMK77373.1 - 1.3e-05 24.3 0.0 0.00066 18.7 0.0 2.2 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AMK77373.1 - 0.0023 17.7 0.1 0.0076 16.0 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain BMC PF00936.19 AMK77373.1 - 0.077 13.0 0.2 0.95 9.5 0.0 2.5 2 0 0 2 2 2 0 BMC domain PhoLip_ATPase_N PF16209.5 AMK77374.1 - 0.18 11.6 0.0 8.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal DUF4794 PF16042.5 AMK77374.1 - 0.26 12.3 4.5 5.3 8.1 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4794) U1snRNP70_N PF12220.8 AMK77375.1 - 0.00011 22.7 24.2 1.5 9.5 1.9 8.3 3 3 2 5 5 5 3 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HC2 PF07382.11 AMK77375.1 - 0.012 15.7 19.2 0.038 14.1 1.3 2.5 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 TetR_C_3 PF08362.11 AMK77375.1 - 0.27 11.2 7.2 3.6 7.5 0.1 3.9 3 2 1 4 4 4 0 YcdC-like protein, C-terminal region Ubiq_cyt_C_chap PF03981.12 AMK77375.1 - 0.99 9.5 19.5 6.7 6.8 0.3 6.5 2 1 3 6 6 6 0 Ubiquinol-cytochrome C chaperone DUF2782 PF11191.8 AMK77376.1 - 3.8e-31 107.1 0.6 4.9e-31 106.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2782) zf-Paramyx-P PF13008.7 AMK77377.1 - 0.13 11.7 0.1 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein AzlD PF05437.12 AMK77378.1 - 0.21 11.8 5.8 1.9 8.7 1.7 2.1 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) adh_short_C2 PF13561.6 AMK77379.1 - 6.5e-53 179.7 1.1 7.3e-53 179.5 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AMK77379.1 - 1.1e-43 148.9 0.1 1.5e-43 148.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK77379.1 - 3.2e-09 37.0 0.5 4.4e-09 36.5 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AMK77379.1 - 0.004 16.6 0.3 0.011 15.2 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AMK77379.1 - 0.0075 15.7 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 AMK77379.1 - 0.025 13.7 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 AMK77379.1 - 0.045 13.1 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HPPK PF01288.20 AMK77380.1 - 3.2e-27 95.3 0.0 3.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 AMK77381.1 - 1.2e-30 106.3 0.0 1.4e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase G3P_acyltransf PF02660.15 AMK77382.1 - 1.9e-51 174.4 14.3 2.1e-51 174.2 14.3 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase ABC2_membrane_5 PF13346.6 AMK77382.1 - 0.23 11.0 5.7 0.46 10.0 5.7 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_M22 PF00814.25 AMK77383.1 - 8e-101 337.3 0.2 9.1e-101 337.1 0.2 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AMK77383.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.4 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus DUF1471 PF07338.13 AMK77383.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Ribosomal_S21 PF01165.20 AMK77384.1 - 1.1e-20 73.1 6.8 1.1e-20 73.1 6.8 1.8 1 1 0 2 2 2 1 Ribosomal protein S21 YqeY PF09424.10 AMK77385.1 - 3.9e-54 182.6 6.6 4.3e-54 182.5 6.6 1.0 1 0 0 1 1 1 1 Yqey-like protein Toprim_N PF08275.11 AMK77386.1 - 1.2e-38 132.1 0.0 2.2e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AMK77386.1 - 2.7e-37 126.5 0.0 8.2e-37 125.0 0.0 1.8 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 AMK77386.1 - 3.3e-19 69.7 4.1 3.4e-19 69.7 2.5 1.9 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding Toprim_2 PF13155.6 AMK77386.1 - 6.2e-16 58.6 0.0 1.5e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 AMK77386.1 - 2.7e-15 56.6 0.0 6.9e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 AMK77386.1 - 1.5e-08 34.8 0.0 5.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 AMK77386.1 - 2.1e-08 34.4 0.0 4.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 AMK77386.1 - 4.9e-07 29.8 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 DnaB-helicase binding domain of primase TyeA PF09059.10 AMK77386.1 - 0.094 12.8 0.3 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 TyeA Sigma70_ner PF04546.13 AMK77387.1 - 1e-41 143.1 5.9 1e-41 143.1 5.9 2.8 4 0 0 4 4 4 1 Sigma-70, non-essential region Sigma70_r3 PF04539.16 AMK77387.1 - 4.6e-31 106.8 3.7 2.4e-30 104.5 1.7 2.9 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r1_1 PF03979.14 AMK77387.1 - 4.3e-30 103.6 5.2 4.3e-30 103.6 5.2 2.7 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 Sigma70_r2 PF04542.14 AMK77387.1 - 8.5e-22 76.7 0.3 1.8e-21 75.6 0.3 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK77387.1 - 1.6e-20 72.4 5.5 9.9e-19 66.6 0.8 2.8 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AMK77387.1 - 2.9e-13 49.6 1.5 2.9e-13 49.6 1.5 2.3 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 V-SNARE_C PF12352.8 AMK77387.1 - 0.00028 21.1 0.2 0.01 16.1 0.0 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus HTH_20 PF12840.7 AMK77387.1 - 0.018 15.1 0.0 0.068 13.2 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Peripla_BP_4 PF13407.6 AMK77387.1 - 0.13 11.8 0.8 0.25 10.9 0.8 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain HTH_25 PF13413.6 AMK77387.1 - 0.76 9.7 3.2 55 3.7 0.0 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain S-AdoMet_synt_C PF02773.16 AMK77388.1 - 6.4e-69 230.3 0.0 1.5e-68 229.1 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AMK77388.1 - 7.2e-46 155.3 0.0 1.6e-45 154.2 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AMK77388.1 - 2e-43 147.1 0.0 3.9e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Anemone_cytotox PF06369.12 AMK77388.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Sea anemone cytotoxic protein AdoHcyase PF05221.17 AMK77389.1 - 1e-138 461.5 0.0 1.8e-74 250.6 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AMK77389.1 - 2.5e-83 278.0 3.5 3.8e-83 277.4 3.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AMK77389.1 - 4.2e-07 29.5 0.2 9.5e-07 28.3 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AMK77389.1 - 0.00012 21.7 0.2 0.00026 20.6 0.2 1.6 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 AMK77389.1 - 0.00029 21.1 0.2 0.00062 20.0 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 AMK77389.1 - 0.033 13.5 2.5 0.27 10.6 2.5 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aminotran_3 PF00202.21 AMK77390.1 - 7.2e-124 413.5 0.0 9.1e-124 413.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III UPF0149 PF03695.13 AMK77390.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Methyltrans_RNA PF04452.14 AMK77391.1 - 1.8e-67 227.0 0.0 2e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase CPBP PF02517.16 AMK77392.1 - 1.9e-09 37.8 16.4 2e-08 34.5 16.4 2.6 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease LPAM_1 PF08139.12 AMK77393.1 - 0.035 14.6 2.1 0.06 13.9 2.1 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Peptidase_C47 PF05543.13 AMK77393.1 - 0.041 13.5 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Staphopain peptidase C47 ATP-synt_ab PF00006.25 AMK77394.1 - 5.3e-63 212.5 0.0 1.7e-62 210.9 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AMK77394.1 - 2.1e-05 25.0 0.0 4.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AMK77394.1 - 0.0008 19.2 0.7 0.0025 17.7 0.7 1.8 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 AMK77394.1 - 0.013 14.9 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 AMK77394.1 - 0.18 11.4 0.2 0.87 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_DE_N PF02823.16 AMK77395.1 - 5.7e-12 45.4 0.0 8.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATPase_gene1 PF09527.10 AMK77396.1 - 4e-11 42.9 8.8 4.6e-11 42.7 8.4 1.3 1 1 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Phage_holin_3_6 PF07332.11 AMK77396.1 - 0.0093 16.0 0.4 0.011 15.7 0.4 1.2 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SLT PF01464.20 AMK77397.1 - 1.3e-21 76.5 0.0 2.4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Alpha-amylase_N PF02903.14 AMK77397.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain PAS_12 PF18095.1 AMK77397.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain ATP-synt_A PF00119.20 AMK77398.1 - 2.3e-41 142.0 14.5 2.9e-41 141.8 14.5 1.0 1 0 0 1 1 1 1 ATP synthase A chain ATP-synt_C PF00137.21 AMK77399.1 - 1.8e-14 53.8 8.8 2.2e-14 53.5 8.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit C MnhB PF04039.13 AMK77399.1 - 0.047 14.0 3.1 0.061 13.6 3.1 1.1 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter Acyl_transf_3 PF01757.22 AMK77400.1 - 1.1e-25 90.4 36.7 1.1e-25 90.4 36.7 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF2517 PF10725.9 AMK77400.1 - 0.091 12.5 0.0 8.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) DUF4131 PF13567.6 AMK77400.1 - 0.95 9.1 0.0 0.95 9.1 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4131) ATP-synt_B PF00430.18 AMK77401.1 - 1.9e-09 37.7 16.3 1.9e-09 37.7 16.3 2.6 1 1 2 3 3 3 1 ATP synthase B/B' CF(0) OSCP PF00213.18 AMK77401.1 - 3e-06 27.5 3.1 3e-06 27.5 3.1 2.4 1 1 1 2 2 2 1 ATP synthase delta (OSCP) subunit Mt_ATP-synt_B PF05405.14 AMK77401.1 - 0.061 12.9 6.7 0.095 12.3 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PUMA PF15826.5 AMK77401.1 - 0.55 10.4 4.6 1.4 9.1 4.6 1.7 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Atg14 PF10186.9 AMK77401.1 - 0.86 8.6 7.9 1 8.4 7.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_ab PF00006.25 AMK77402.1 - 2.9e-61 206.8 0.0 4e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AMK77402.1 - 2.9e-20 72.9 0.0 5.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA_16 PF13191.6 AMK77402.1 - 0.079 13.3 0.4 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 AMK77402.1 - 0.16 11.7 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 AMK77402.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC ATP-synt PF00231.19 AMK77403.1 - 1.1e-26 94.2 0.0 2e-26 93.3 0.0 1.4 1 1 0 1 1 1 1 ATP synthase CDT1_C PF16679.5 AMK77403.1 - 0.08 13.4 1.1 0.64 10.5 0.0 2.5 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Adeno_E1B_19K PF01691.16 AMK77403.1 - 0.11 12.1 0.2 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen GlnE PF03710.15 AMK77403.1 - 0.14 11.5 1.5 0.15 11.5 0.2 1.7 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase SlyX PF04102.12 AMK77403.1 - 1.6 9.4 5.9 16 6.2 0.1 3.3 3 0 0 3 3 3 0 SlyX ParE_toxin PF05016.15 AMK77404.1 - 9.1e-16 58.3 0.3 1e-15 58.1 0.3 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Gp49 PF05973.14 AMK77404.1 - 0.077 13.1 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) Sigma54_activat PF00158.26 AMK77406.1 - 7.8e-69 230.7 0.0 1.1e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK77406.1 - 3.8e-20 72.4 0.0 8.4e-20 71.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain PAS_9 PF13426.7 AMK77406.1 - 1.3e-08 35.0 0.0 3.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain HTH_8 PF02954.19 AMK77406.1 - 9.7e-08 31.7 0.2 1.9e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK77406.1 - 2.1e-07 31.0 0.0 4.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PAS PF00989.25 AMK77406.1 - 3.1e-06 27.1 0.0 9.9e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold AAA PF00004.29 AMK77406.1 - 9.3e-05 22.9 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AMK77406.1 - 0.0013 18.2 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 AMK77406.1 - 0.0013 17.7 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain PAS_4 PF08448.10 AMK77406.1 - 0.0029 17.8 0.1 0.054 13.8 0.0 3.0 3 1 0 3 3 3 1 PAS fold DHDPS PF00701.22 AMK77406.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Gelsolin PF00626.22 AMK77406.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat AAA_7 PF12775.7 AMK77406.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PAS_8 PF13188.7 AMK77406.1 - 0.1 12.6 0.0 0.38 10.8 0.0 2.0 1 0 0 1 1 1 0 PAS domain IstB_IS21 PF01695.17 AMK77406.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 AMK77406.1 - 0.13 11.4 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Lactamase_B PF00753.27 AMK77407.1 - 4.5e-17 62.7 4.0 9.6e-16 58.4 4.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK77407.1 - 0.045 13.3 1.0 0.069 12.7 1.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TauE PF01925.19 AMK77408.1 - 1.2e-50 172.3 44.8 1.2e-50 172.3 44.8 2.0 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE MFS_1 PF07690.16 AMK77408.1 - 1.1 8.1 43.2 14 4.4 43.3 2.3 1 1 0 1 1 1 0 Major Facilitator Superfamily EMP70 PF02990.16 AMK77408.1 - 6.7 5.3 10.5 0.89 8.1 1.9 2.1 2 0 0 2 2 2 0 Endomembrane protein 70 Cu-oxidase_3 PF07732.15 AMK77409.1 - 1.1e-24 86.7 0.1 5e-23 81.4 0.2 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 AMK77409.1 - 2.1e-20 72.9 4.6 3.7e-19 68.8 0.3 3.1 3 1 0 3 3 3 2 Multicopper oxidase DUF3601 PF12208.8 AMK77409.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) DsbD_2 PF13386.6 AMK77410.1 - 1.3e-41 142.8 21.8 1.3e-41 142.8 21.8 1.4 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region HMA PF00403.26 AMK77410.1 - 1.4e-10 41.4 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain DsbD PF02683.15 AMK77410.1 - 9.4e-09 35.5 8.3 9.4e-09 35.5 8.3 1.6 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region PSII_BNR PF14870.6 AMK77412.1 - 2.8e-64 217.3 47.0 1.9e-11 43.8 0.9 8.8 2 1 8 10 10 10 10 Photosynthesis system II assembly factor YCF48 KAP_NTPase PF07693.14 AMK77412.1 - 1.4e-18 67.2 0.0 3.5e-16 59.4 0.0 3.1 1 1 0 1 1 1 1 KAP family P-loop domain Sortilin-Vps10 PF15902.5 AMK77412.1 - 5.5e-11 41.9 8.5 0.019 13.8 0.0 6.2 3 2 2 6 6 6 4 Sortilin, neurotensin receptor 3, AAA_16 PF13191.6 AMK77412.1 - 1.6e-06 28.6 0.0 0.031 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain BNR PF02012.20 AMK77412.1 - 0.00036 20.1 66.8 0.85 9.9 0.1 14.5 14 0 0 14 14 14 2 BNR/Asp-box repeat AAA_22 PF13401.6 AMK77412.1 - 0.0028 17.9 0.0 2.3 8.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain Torsin PF06309.11 AMK77412.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Torsin dCache_1 PF02743.18 AMK77412.1 - 0.029 14.1 0.5 12 5.6 0.0 4.4 4 3 1 5 5 5 0 Cache domain AAA_7 PF12775.7 AMK77412.1 - 0.2 11.1 0.0 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4131 PF13567.6 AMK77412.1 - 0.86 9.2 15.3 1.6 8.3 2.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DUF2157 PF09925.9 AMK77412.1 - 0.92 9.3 7.4 0.45 10.3 0.0 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) EAL PF00563.20 AMK77413.1 - 1.5e-69 234.2 0.0 2.5e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK77413.1 - 2.6e-48 163.8 0.0 5e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK77413.1 - 1.2e-22 80.2 0.1 3.1e-22 78.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 AMK77413.1 - 1.3e-17 64.0 0.0 3.2e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK77413.1 - 1.3e-15 57.4 0.0 2.9e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AMK77413.1 - 2.4e-11 43.8 0.0 5.5e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK77413.1 - 5.5e-09 36.3 0.0 1.3e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK77413.1 - 4.2e-08 33.0 0.0 2.7e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 AMK77413.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain HATPase_c PF02518.26 AMK77414.1 - 3e-29 101.8 0.1 5.5e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK77414.1 - 2.6e-19 69.0 3.0 1.3e-17 63.6 0.1 3.4 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 AMK77414.1 - 0.0067 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AMK77414.1 - 0.038 14.6 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 GAF domain HATPase_c_3 PF13589.6 AMK77414.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSCB_C PF07743.13 AMK77414.1 - 0.33 11.5 0.1 0.33 11.5 0.1 3.0 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain HrpJ PF07201.11 AMK77414.1 - 0.5 10.7 5.1 4.7 7.5 0.4 2.8 2 0 0 2 2 2 0 HrpJ-like domain DUF1638 PF07796.11 AMK77415.1 - 2.4e-24 86.2 0.3 3e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1638) IKKbetaNEMObind PF12179.8 AMK77415.1 - 0.12 12.5 0.3 9.4 6.4 0.3 2.5 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain URO-D PF01208.17 AMK77416.1 - 1.3e-38 133.0 0.0 1.5e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) B12-binding PF02310.19 AMK77417.1 - 1.5e-17 63.8 0.5 2.7e-17 62.9 0.5 1.5 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 AMK77417.1 - 0.00045 20.6 0.1 0.0034 17.8 0.0 2.4 2 1 1 3 3 3 1 B12 binding domain XPG_I_2 PF12813.7 AMK77417.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing RACo_C_ter PF14574.6 AMK77418.1 - 4.5e-51 173.4 0.0 1.7e-50 171.5 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of RACo the ASKHA domain Raco_middle PF17651.1 AMK77418.1 - 1.2e-24 86.9 0.0 1.9e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 RACo middle region Fer2 PF00111.27 AMK77418.1 - 3.7e-07 30.0 0.4 9.9e-07 28.6 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Pan_kinase PF03309.14 AMK77418.1 - 0.062 13.1 0.3 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Type III pantothenate kinase Peptidase_M15_4 PF13539.6 AMK77418.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HATPase_c PF02518.26 AMK77419.1 - 7.5e-25 87.6 0.0 1.4e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK77419.1 - 4.1e-23 81.7 0.0 7.7e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AMK77419.1 - 9.1e-11 41.6 0.1 5.1e-10 39.3 0.1 2.3 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AMK77419.1 - 0.00046 20.1 0.0 0.002 18.0 0.0 2.0 3 0 0 3 3 3 1 GHKL domain HATPase_c_2 PF13581.6 AMK77419.1 - 0.0038 17.2 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK77419.1 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK77420.1 - 6.3e-22 77.9 0.1 2.1e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain DUF815 PF05673.13 AMK77421.1 - 6.9e-100 333.3 0.0 7.8e-100 333.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 AMK77421.1 - 2.1e-06 28.2 0.0 1.5e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK77421.1 - 6.8e-06 26.6 0.0 1.3e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AMK77421.1 - 0.00024 21.4 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AMK77421.1 - 0.0017 18.4 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK77421.1 - 0.0091 16.5 0.0 0.018 15.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter CLP1_P PF16575.5 AMK77421.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 AMK77421.1 - 0.028 14.2 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 AMK77421.1 - 0.028 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 AMK77421.1 - 0.031 14.2 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 AMK77421.1 - 0.032 14.6 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 AMK77421.1 - 0.034 13.7 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 AMK77421.1 - 0.037 13.4 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 AMK77421.1 - 0.046 12.6 0.0 0.12 11.2 0.0 1.6 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.6 AMK77421.1 - 0.05 13.8 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AMK77421.1 - 0.072 13.6 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AMK77421.1 - 0.087 12.9 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ank_4 PF13637.6 AMK77422.1 - 1.7e-23 82.6 1.3 7.5e-09 36.0 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 AMK77422.1 - 1.2e-17 63.7 2.1 2.6e-07 30.8 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 AMK77422.1 - 3.9e-17 62.6 0.4 8.6e-12 45.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 AMK77422.1 - 7.1e-14 50.6 0.5 0.0012 19.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 AMK77422.1 - 1.8e-13 50.3 2.8 4e-05 23.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat UDPG_MGDP_dh_C PF03720.15 AMK77422.1 - 0.17 12.4 0.1 10 6.6 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Catalase PF00199.19 AMK77423.1 - 3.9e-174 579.2 0.2 4.6e-174 579.0 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 AMK77423.1 - 1.2e-17 63.8 0.1 3.8e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive LysR_substrate PF03466.20 AMK77424.1 - 7.2e-50 169.3 2.7 8.7e-50 169.0 2.7 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK77424.1 - 1.2e-19 70.0 0.0 2.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 AMK77424.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_1 PF00561.20 AMK77425.1 - 2.5e-22 79.8 0.8 4.8e-20 72.3 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK77425.1 - 2.9e-18 67.3 1.7 4.1e-18 66.8 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK77425.1 - 5e-15 55.4 0.4 7.5e-15 54.8 0.4 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AMK77425.1 - 1.9e-09 36.6 0.1 4.2e-09 35.5 0.1 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 AMK77425.1 - 3.3e-08 33.6 1.2 0.036 13.9 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 AMK77425.1 - 6.2e-05 22.8 0.6 0.0008 19.2 0.1 2.3 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_4 PF08386.10 AMK77425.1 - 6.2e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 AMK77425.1 - 0.0032 17.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 AMK77425.1 - 0.014 15.3 0.2 1.7 8.5 0.2 2.4 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.13 AMK77425.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1057 PF06342.12 AMK77425.1 - 0.07 12.2 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2920 PF11144.8 AMK77425.1 - 0.089 11.9 0.1 0.54 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Palm_thioest PF02089.15 AMK77425.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 AMK77425.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 AMK77425.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 AMK77425.1 - 0.16 11.4 0.1 0.46 10.0 0.1 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Fae PF08714.11 AMK77426.1 - 3.9e-61 205.7 0.1 4.3e-61 205.5 0.1 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Ank_2 PF12796.7 AMK77427.1 - 2.9e-22 79.1 6.8 1.9e-10 41.2 0.5 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AMK77427.1 - 3.9e-15 56.0 9.0 4.7e-05 23.8 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 AMK77427.1 - 1.4e-14 53.9 1.4 2.8e-06 27.5 0.3 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 AMK77427.1 - 1.2e-13 49.8 1.8 0.0053 17.2 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 AMK77427.1 - 3e-12 46.4 6.5 0.0015 18.9 0.7 4.2 4 0 0 4 4 4 3 Ankyrin repeat HEM4 PF02602.15 AMK77427.1 - 0.026 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD SUFU PF05076.13 AMK77428.1 - 0.0003 20.8 0.0 0.00043 20.3 0.0 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) LRV PF01816.17 AMK77429.1 - 1.3e-31 106.8 27.6 3.4e-05 24.0 1.9 7.3 7 0 0 7 7 7 7 Leucine rich repeat variant LRV_FeS PF05484.11 AMK77429.1 - 2.6e-13 49.7 0.2 4.6e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 LRV protein FeS4 cluster HEAT PF02985.22 AMK77429.1 - 2.8e-10 39.6 8.6 5.1 7.6 0.1 7.8 7 1 1 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 AMK77429.1 - 2.4e-06 27.9 12.1 0.23 11.9 3.2 6.1 1 1 1 2 2 2 2 HEAT repeats RHH_6 PF16762.5 AMK77429.1 - 0.056 14.1 0.1 6 7.6 0.0 2.9 3 1 0 3 3 3 0 Ribbon-helix-helix domain Flavodoxin_1 PF00258.25 AMK77430.1 - 1.2e-21 77.4 0.0 1.4e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 AMK77430.1 - 0.0017 18.6 0.0 0.0037 17.5 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 AMK77430.1 - 0.01 15.5 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain DUF883 PF05957.13 AMK77432.1 - 0.062 13.9 7.8 0.056 14.0 2.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_S PF02609.16 AMK77432.1 - 0.68 10.0 5.8 9.7 6.3 0.3 3.1 3 0 0 3 3 3 0 Exonuclease VII small subunit EAL PF00563.20 AMK77433.1 - 4.1e-71 239.3 0.5 8.7e-71 238.2 0.1 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK77433.1 - 1.5e-54 184.1 0.3 3.7e-54 182.8 0.3 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK77433.1 - 1.3e-24 86.5 0.0 2.7e-12 46.9 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AMK77433.1 - 3.1e-20 72.2 0.1 2.1e-09 37.4 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 AMK77433.1 - 6.9e-17 61.0 0.5 3.1e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 AMK77433.1 - 4.3e-14 52.7 0.0 0.0089 16.3 0.0 4.0 3 1 0 3 3 3 3 PAS fold PAS_7 PF12860.7 AMK77433.1 - 3.8e-10 40.0 0.0 3.1e-06 27.3 0.0 3.9 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 AMK77433.1 - 3.5e-09 36.8 0.6 0.0018 18.5 0.0 3.9 3 1 0 3 3 3 2 PAS fold PAS_12 PF18095.1 AMK77433.1 - 2.2e-05 24.1 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 UPF0242 C-terminal PAS-like domain Glucokinase PF02685.16 AMK77434.1 - 6.7e-101 337.4 0.0 7.5e-101 337.3 0.0 1.0 1 0 0 1 1 1 1 Glucokinase Glyco_hydro_15 PF00723.21 AMK77435.1 - 1.5e-134 449.2 0.0 2e-134 448.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Adeno_E3B PF03376.14 AMK77435.1 - 0.15 12.3 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3B protein dUTPase PF00692.19 AMK77436.1 - 6.6e-07 29.1 0.0 4e-06 26.5 0.0 1.9 1 1 1 2 2 2 1 dUTPase Flagellar_put PF12611.8 AMK77436.1 - 0.1 12.4 1.6 0.21 11.4 1.6 1.5 1 0 0 1 1 1 0 Putative flagellar TetR_C_13 PF16925.5 AMK77437.1 - 3.6e-25 88.1 0.0 5.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AMK77437.1 - 3.2e-11 42.8 0.2 6.1e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AMK77437.1 - 0.013 15.8 0.1 0.023 15.0 0.1 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-H2C2 PF09337.10 AMK77437.1 - 0.18 12.0 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger DUF4242 PF14026.6 AMK77439.1 - 1.8e-29 101.7 0.0 2e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4242) SBP56 PF05694.11 AMK77440.1 - 2.9e-47 161.5 1.3 2.7e-45 155.1 1.3 2.5 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 AMK77440.1 - 0.0027 17.0 0.0 0.094 11.9 0.0 2.4 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Response_reg PF00072.24 AMK77441.1 - 5e-28 97.5 0.1 6.7e-27 93.9 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain THOC7 PF05615.13 AMK77441.1 - 0.078 13.3 0.0 0.078 13.3 0.0 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 V-ATPase_G_2 PF16999.5 AMK77441.1 - 0.4 11.1 4.9 0.57 10.6 0.2 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit CHAD PF05235.14 AMK77441.1 - 0.47 10.4 3.2 0.21 11.6 1.0 1.5 2 0 0 2 2 2 0 CHAD domain zf-ZPR1 PF03367.13 AMK77441.1 - 1.2 9.0 3.5 6.6 6.6 3.5 2.1 1 1 0 1 1 1 0 ZPR1 zinc-finger domain Fib_alpha PF08702.10 AMK77441.1 - 6.4 7.0 6.3 1.2e+02 2.9 6.2 2.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CCP_MauG PF03150.14 AMK77444.1 - 8e-52 175.9 0.1 2.1e-45 155.0 0.0 3.1 2 1 0 2 2 2 2 Di-haem cytochrome c peroxidase SCO1-SenC PF02630.14 AMK77444.1 - 7.1e-16 58.3 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Cytochrom_C PF00034.21 AMK77444.1 - 4.8e-06 27.6 0.0 0.0077 17.4 0.0 3.2 2 1 0 2 2 2 2 Cytochrome c Defensin_5 PF18251.1 AMK77444.1 - 0.37 10.9 1.1 2.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Fungal defensin Copsin Response_reg PF00072.24 AMK77445.1 - 4.9e-30 104.0 0.2 7e-30 103.5 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK77445.1 - 7.7e-26 90.0 0.1 1.5e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal BRCT_3 PF18428.1 AMK77445.1 - 0.042 13.9 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PhoR PF11808.8 AMK77446.1 - 3.5e-21 75.4 0.6 6.2e-21 74.6 0.6 1.4 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR HATPase_c PF02518.26 AMK77446.1 - 1.5e-18 67.3 0.0 6.3e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK77446.1 - 2.3e-17 62.8 1.9 2.5e-17 62.7 0.2 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AMK77446.1 - 0.073 13.1 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 PAS domain DUF4393 PF14337.6 AMK77446.1 - 0.15 11.9 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) GGDEF PF00990.21 AMK77447.1 - 1.7e-38 131.9 0.1 3.1e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MASE1 PF05231.14 AMK77447.1 - 1.7e-30 106.2 45.0 2.4e-30 105.7 45.0 1.1 1 0 0 1 1 1 1 MASE1 PAS_3 PF08447.12 AMK77447.1 - 1.4e-20 73.4 1.8 1.1e-09 38.4 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 AMK77447.1 - 5.5e-19 68.4 0.1 4e-15 56.0 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK77447.1 - 6.4e-11 42.3 0.1 8.7e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AMK77447.1 - 5.9e-06 26.5 0.1 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AMK77447.1 - 4.2e-05 23.4 0.0 0.00015 21.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain EptA_B_N PF08019.12 AMK77447.1 - 0.088 12.7 3.3 9 6.2 0.0 2.8 2 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Cyt_bd_oxida_I PF01654.17 AMK77448.1 - 2.6e-105 352.5 24.0 2.9e-105 352.3 24.0 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I PSI_PSAK PF01241.18 AMK77448.1 - 0.024 14.6 0.3 0.12 12.4 0.2 2.3 1 1 0 1 1 1 0 Photosystem I psaG / psaK Cyt_bd_oxida_II PF02322.15 AMK77449.1 - 8.3e-72 242.1 28.0 9.4e-72 241.9 28.0 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF502 PF04367.13 AMK77450.1 - 1.2e-23 83.0 0.5 2.6e-23 81.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF502) CinA PF02464.17 AMK77451.1 - 5.7e-57 191.6 0.1 6.9e-57 191.4 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein GGDEF PF00990.21 AMK77452.1 - 2.4e-47 160.7 0.2 6.4e-47 159.3 0.0 1.8 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain MASE1 PF05231.14 AMK77452.1 - 7.6e-38 130.3 26.9 1.1e-37 129.8 26.9 1.2 1 0 0 1 1 1 1 MASE1 PAS_9 PF13426.7 AMK77452.1 - 2.4e-19 69.5 0.0 4.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK77452.1 - 1.9e-12 47.2 0.0 4.6e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK77452.1 - 1.6e-09 38.0 0.3 9.7e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 AMK77452.1 - 2.7e-07 30.8 0.0 6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK77452.1 - 3e-06 27.1 0.0 1.3e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 PAS domain GGDEF_2 PF17853.1 AMK77452.1 - 0.017 15.4 0.4 0.07 13.4 0.4 2.1 1 0 0 1 1 1 0 GGDEF-like domain DASH_Spc34 PF08657.10 AMK77452.1 - 0.04 13.7 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 PAS_12 PF18095.1 AMK77452.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Cluap1 PF10234.9 AMK77452.1 - 0.068 12.6 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Peptidase_M48 PF01435.18 AMK77453.1 - 3e-37 128.3 0.1 4.2e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 Aminotran_1_2 PF00155.21 AMK77454.1 - 7.2e-47 160.3 0.0 8e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 AMK77454.1 - 1.6e-06 27.2 0.0 2.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase THDPS_N_2 PF14805.6 AMK77455.1 - 3.4e-27 94.4 0.8 6.2e-27 93.6 0.8 1.4 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep_2 PF14602.6 AMK77455.1 - 1.3e-15 56.8 4.0 1.3e-15 56.8 4.0 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 AMK77455.1 - 8.8e-12 44.3 14.8 3.1e-08 33.0 2.6 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Aldose_epim PF01263.20 AMK77457.1 - 0.00078 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase ArsC PF03960.15 AMK77460.1 - 7.7e-18 64.3 0.0 8.6e-18 64.1 0.0 1.0 1 0 0 1 1 1 1 ArsC family Peptidase_M20 PF01546.28 AMK77461.1 - 3.2e-42 144.6 0.1 4e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AMK77461.1 - 7.9e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M18 PF02127.15 AMK77461.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) CHASE PF03924.13 AMK77462.1 - 4.2e-59 199.7 0.1 8.8e-59 198.6 0.1 1.6 1 0 0 1 1 1 1 CHASE domain GGDEF PF00990.21 AMK77462.1 - 1.8e-48 164.4 0.0 3.3e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK77462.1 - 2.9e-28 98.2 0.0 1.5e-18 67.0 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AMK77462.1 - 4.9e-26 91.0 0.0 7.9e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AMK77462.1 - 8.1e-18 64.0 0.0 1e-07 31.8 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 AMK77462.1 - 1.6e-16 60.5 0.0 1.9e-07 31.3 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AMK77462.1 - 3.6e-13 49.6 0.0 3.2e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold DUF4381 PF14316.6 AMK77462.1 - 0.072 13.3 2.5 0.41 10.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SPOR PF05036.13 AMK77462.1 - 0.1 13.0 0.1 4.2 7.8 0.0 2.7 2 0 0 2 2 2 0 Sporulation related domain AIM24 PF01987.17 AMK77463.1 - 2.7e-61 206.9 0.7 3e-61 206.7 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RadC PF04002.15 AMK77464.1 - 5.9e-43 145.7 0.0 8.4e-43 145.2 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 AMK77464.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HHH_5 PF14520.6 AMK77464.1 - 0.042 14.4 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain TrkA_TMD PF18613.1 AMK77464.1 - 0.2 11.1 0.5 0.36 10.3 0.5 1.4 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain DFP PF04127.15 AMK77465.1 - 8.2e-70 234.4 0.8 1.9e-68 230.0 0.0 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AMK77465.1 - 4.2e-48 163.1 0.1 8.5e-48 162.1 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein PspC PF04024.12 AMK77465.1 - 0.0047 16.7 0.1 0.0096 15.7 0.1 1.5 1 0 0 1 1 1 1 PspC domain Glyco_trans_4_4 PF13579.6 AMK77465.1 - 0.05 14.0 6.3 0.049 14.1 1.6 2.6 1 1 0 2 2 2 0 Glycosyl transferase 4-like domain DrsE PF02635.15 AMK77465.1 - 0.098 13.0 0.3 1.3 9.5 0.1 2.5 2 0 0 2 2 2 0 DsrE/DsrF-like family Glyco_transf_4 PF13439.6 AMK77465.1 - 0.13 12.3 0.3 0.36 10.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 dUTPase PF00692.19 AMK77466.1 - 2.6e-39 133.8 0.0 3e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF1350 PF07082.11 AMK77466.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) PGM_PMM_I PF02878.16 AMK77467.1 - 1.1e-37 128.9 0.0 2.2e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AMK77467.1 - 2.3e-28 98.8 0.1 6.9e-28 97.3 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AMK77467.1 - 1.2e-18 67.4 0.0 2.6e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AMK77467.1 - 3.5e-12 46.3 0.0 1.3e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain dCache_1 PF02743.18 AMK77467.1 - 2.4e-05 24.3 0.8 0.00011 22.1 0.7 2.1 2 1 0 2 2 2 1 Cache domain AA_kinase PF00696.28 AMK77468.1 - 6.3e-41 140.6 4.5 7.3e-41 140.3 4.5 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF4124 PF13511.6 AMK77469.1 - 1.2e-08 35.2 0.4 3.9e-08 33.5 0.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4124) DUF4254 PF14063.6 AMK77469.1 - 0.059 13.2 5.1 0.52 10.1 5.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) Spc7 PF08317.11 AMK77469.1 - 7 5.4 19.9 0.039 12.8 7.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein YGGT PF02325.17 AMK77470.1 - 2.6e-40 136.7 12.2 1.7e-20 73.2 3.8 2.4 2 0 0 2 2 2 2 YGGT family P5CR_dimer PF14748.6 AMK77471.1 - 7.5e-35 119.3 2.0 1.4e-34 118.4 2.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AMK77471.1 - 4.1e-21 75.4 0.9 9.2e-21 74.2 0.9 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AMK77471.1 - 1.6e-06 28.4 0.5 4.1e-06 27.1 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AMK77471.1 - 0.0016 18.4 4.1 0.013 15.4 4.1 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AMK77471.1 - 0.0036 18.1 0.3 0.015 16.1 0.1 2.1 2 1 1 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 AMK77471.1 - 0.063 13.3 0.2 0.22 11.6 0.2 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase PTS_IIB PF02302.17 AMK77471.1 - 0.087 13.5 0.3 2.7 8.8 0.0 2.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit MurJ PF03023.14 AMK77472.1 - 1e-137 459.4 32.2 1.3e-137 459.1 32.2 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 AMK77472.1 - 1.5e-11 44.5 18.2 1.5e-11 44.5 18.2 4.2 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 AMK77472.1 - 3.9e-05 23.4 4.5 3.9e-05 23.4 4.5 3.5 4 1 0 4 4 4 2 MatE Ribosomal_S20p PF01649.18 AMK77473.1 - 7.9e-28 96.9 10.5 8.7e-28 96.8 10.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 PSII_Pbs31 PF18240.1 AMK77473.1 - 0.024 15.0 2.1 0.033 14.6 0.6 2.0 1 1 0 1 1 1 0 Photosystem II Psb31 protein 4HB_MCP_1 PF12729.7 AMK77473.1 - 0.025 14.1 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CysG_dimeriser PF10414.9 AMK77473.1 - 0.13 12.0 4.3 0.32 10.8 4.3 1.8 1 1 0 1 1 1 0 Sirohaem synthase dimerisation region GFO_IDH_MocA PF01408.22 AMK77475.1 - 1.1e-21 77.8 0.0 2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 AMK77475.1 - 1.5e-06 28.2 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ank_2 PF12796.7 AMK77476.1 - 1.5e-07 31.9 0.1 2.2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 AMK77476.1 - 5e-07 30.1 0.1 0.00042 20.8 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 AMK77476.1 - 0.00022 21.4 0.0 0.12 13.0 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 AMK77476.1 - 0.0012 19.2 0.3 0.12 12.9 0.2 2.9 1 1 1 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 AMK77476.1 - 0.029 14.7 0.1 0.071 13.5 0.1 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) AAA_2 PF07724.14 AMK77477.1 - 3.1e-59 199.9 1.4 9.7e-56 188.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AMK77477.1 - 1.4e-35 121.4 4.6 1.4e-35 121.4 4.6 2.6 2 0 0 2 2 2 1 AAA lid domain Clp_N PF02861.20 AMK77477.1 - 4e-27 94.1 1.6 1.7e-12 47.2 0.1 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 AMK77477.1 - 1.1e-26 93.8 0.8 8.3e-13 48.9 0.0 3.7 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AMK77477.1 - 2.5e-25 88.3 0.0 2e-24 85.4 0.0 2.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AMK77477.1 - 4.9e-19 68.7 0.8 5.9e-13 49.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK77477.1 - 2.2e-12 47.7 3.3 6.8e-05 23.3 0.0 4.6 3 2 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 AMK77477.1 - 4.2e-09 36.3 0.1 4.2e-06 26.6 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 AMK77477.1 - 6e-08 33.0 4.9 0.02 15.1 0.1 4.7 3 2 0 3 3 3 2 AAA domain TniB PF05621.11 AMK77477.1 - 1.3e-06 27.9 0.1 0.0035 16.8 0.1 3.5 2 1 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 AMK77477.1 - 1.4e-06 28.4 0.9 0.18 11.7 0.0 4.3 3 2 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 AMK77477.1 - 1.7e-06 27.9 0.0 0.0032 17.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 AMK77477.1 - 2.3e-06 27.4 0.1 0.13 12.0 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 AMK77477.1 - 3.1e-06 27.8 0.1 0.058 13.9 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 AMK77477.1 - 4.4e-06 26.7 0.0 0.087 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 AMK77477.1 - 1.7e-05 24.4 0.0 0.1 12.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 AMK77477.1 - 6e-05 22.8 0.9 3.5 7.4 0.0 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 AMK77477.1 - 7.7e-05 22.9 0.0 0.38 11.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 AMK77477.1 - 0.00012 21.5 0.1 0.76 9.1 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AMK77477.1 - 0.00013 22.2 0.8 3.3 7.9 0.0 4.0 3 1 0 3 3 3 2 AAA domain DUF815 PF05673.13 AMK77477.1 - 0.0002 20.6 0.1 0.15 11.2 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 AMK77477.1 - 0.00054 20.3 0.2 1.5 9.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_19 PF13245.6 AMK77477.1 - 0.00054 20.3 0.1 0.097 13.0 0.1 3.2 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 AMK77477.1 - 0.00075 19.4 0.9 1.5 8.7 0.0 3.1 4 0 0 4 4 2 2 RsgA GTPase TsaE PF02367.17 AMK77477.1 - 0.00077 19.5 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 AMK77477.1 - 0.0011 19.5 1.4 0.47 11.0 0.0 3.7 4 1 0 4 4 3 1 ABC transporter AAA_3 PF07726.11 AMK77477.1 - 0.0012 18.7 0.1 1.2 9.0 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 AMK77477.1 - 0.0021 18.1 0.0 1.4 8.9 0.0 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit NACHT PF05729.12 AMK77477.1 - 0.0033 17.4 0.0 0.23 11.4 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AMK77477.1 - 0.0048 16.5 0.0 0.32 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AMK77477.1 - 0.0058 16.4 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AMK77477.1 - 0.0058 15.9 0.0 0.88 8.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.17 AMK77477.1 - 0.0066 16.2 0.0 0.3 10.8 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DNA_pol3_delta2 PF13177.6 AMK77477.1 - 0.0071 16.1 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit NTPase_1 PF03266.15 AMK77477.1 - 0.012 15.6 0.1 4.6 7.1 0.1 3.5 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 AMK77477.1 - 0.014 15.1 2.6 9.4 5.9 0.4 4.3 3 2 0 3 3 2 0 AAA domain AAA_33 PF13671.6 AMK77477.1 - 0.019 15.1 0.0 18 5.5 0.0 3.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 AMK77477.1 - 0.052 13.3 0.0 0.98 9.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 AMK77477.1 - 0.077 13.1 0.0 42 4.3 0.0 3.8 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_23 PF13476.6 AMK77477.1 - 2.9 8.4 0.0 2.9 8.4 0.0 4.7 2 1 2 4 4 3 0 AAA domain AAA_17 PF13207.6 AMK77477.1 - 3 8.3 6.4 12 6.3 0.0 4.0 4 0 0 4 4 3 0 AAA domain CSD PF00313.22 AMK77478.1 - 5.4e-29 99.8 0.1 6.5e-29 99.6 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AMK77478.1 - 6.1e-05 22.6 0.1 7.6e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 AMK77478.1 - 0.052 13.4 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Haem_bd PF14376.6 AMK77479.1 - 0.012 15.5 0.0 0.046 13.7 0.0 1.8 1 1 1 2 2 2 0 Haem-binding domain Radical_SAM PF04055.21 AMK77481.1 - 1e-10 42.2 0.0 3e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily GXGXG PF01493.19 AMK77482.1 - 1.5e-17 63.9 12.9 3e-17 62.8 12.9 1.5 1 1 0 1 1 1 1 GXGXG motif FTR_C PF02741.15 AMK77483.1 - 1.2e-64 216.8 0.2 1.2e-64 216.8 0.2 1.6 2 0 0 2 2 2 1 FTR, proximal lobe FTR PF01913.18 AMK77483.1 - 4.6e-63 211.4 0.0 8.1e-63 210.6 0.0 1.4 1 0 0 1 1 1 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase Amidohydro_3 PF07969.11 AMK77484.1 - 2.6e-57 195.4 0.8 3e-57 195.1 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 AMK77484.1 - 0.0014 18.0 0.8 0.29 10.4 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family TPP_enzyme_M PF00205.22 AMK77485.1 - 0.0033 17.2 0.5 0.029 14.1 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Lyase_8_C PF02884.17 AMK77485.1 - 0.13 12.7 0.1 0.29 11.7 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Pterin_4a PF01329.19 AMK77486.1 - 6.6e-25 87.1 0.3 7.7e-25 86.9 0.3 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase MORN_2 PF07661.13 AMK77486.1 - 0.083 13.1 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 MORN repeat variant SspB PF04386.13 AMK77487.1 - 1.9e-33 115.6 0.0 2.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Stringent starvation protein B GST_N PF02798.20 AMK77488.1 - 2.8e-14 53.2 0.0 5.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AMK77488.1 - 3.8e-13 49.7 0.0 9.5e-13 48.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK77488.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 AMK77488.1 - 3.6e-06 27.1 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 AMK77488.1 - 0.00092 19.2 0.0 0.0025 17.8 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 AMK77488.1 - 0.022 15.3 0.0 0.049 14.2 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PhoU_div PF01865.16 AMK77489.1 - 6.3e-13 48.6 1.9 1.1e-12 47.8 1.9 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF47 PHO4 PF01384.20 AMK77490.1 - 7.1e-81 271.9 27.8 3.6e-80 269.5 27.8 1.8 1 1 0 1 1 1 1 Phosphate transporter family Gly-zipper_OmpA PF13436.6 AMK77491.1 - 4.9e-09 35.8 37.1 6.9e-09 35.3 37.1 1.2 1 0 0 1 1 1 1 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 AMK77491.1 - 8.1e-06 25.5 40.1 0.00026 20.7 40.2 2.1 1 1 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AMK77491.1 - 6e-05 22.9 34.8 6e-05 22.9 34.8 2.1 1 1 1 2 2 2 2 Glycine zipper TraT PF05818.12 AMK77491.1 - 0.00054 19.7 4.0 0.0006 19.6 4.0 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Sporozoite_P67 PF05642.11 AMK77491.1 - 0.64 8.0 5.0 0.66 8.0 5.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1269 PF06897.12 AMK77491.1 - 4.6 7.6 19.3 40 4.6 18.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) Ribosomal_L34 PF00468.17 AMK77492.1 - 8.9e-25 86.4 7.3 9.5e-25 86.3 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Ribonuclease_P PF00825.18 AMK77493.1 - 1.8e-27 95.6 0.2 2e-27 95.4 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease P YidC_periplas PF14849.6 AMK77494.1 - 9.9e-82 275.0 6.4 1.5e-80 271.1 6.4 2.0 1 1 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 AMK77494.1 - 2.1e-58 196.9 8.2 2.1e-58 196.9 8.2 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein ASH PF15780.5 AMK77494.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MnmE_helical PF12631.7 AMK77495.1 - 2.3e-56 191.3 7.3 2.7e-56 191.0 7.3 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 AMK77495.1 - 3.7e-37 127.2 0.0 1.6e-36 125.1 0.0 2.1 3 0 0 3 3 3 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 AMK77495.1 - 2.9e-23 82.1 0.3 6e-23 81.1 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AMK77495.1 - 1.7e-10 40.6 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AMK77495.1 - 9.6e-06 25.6 0.2 0.0014 18.5 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 AMK77495.1 - 9.9e-06 25.7 0.1 0.0007 19.7 0.0 2.6 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 AMK77495.1 - 1.8e-05 24.2 0.0 3.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 AMK77495.1 - 0.00085 19.8 0.1 0.0022 18.5 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 AMK77495.1 - 0.011 15.9 1.8 0.041 14.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 AMK77495.1 - 0.042 14.2 5.0 0.14 12.5 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain Ras PF00071.22 AMK77495.1 - 0.044 13.4 0.0 0.16 11.6 0.0 2.0 2 1 0 2 2 2 0 Ras family MMR_HSR1_Xtn PF16897.5 AMK77495.1 - 0.051 13.6 0.0 15 5.7 0.0 3.0 3 1 0 3 3 3 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 AMK77495.1 - 0.09 13.3 0.0 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Peptidase_C31 PF05410.13 AMK77496.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha Nitroreductase PF00881.24 AMK77497.1 - 1.2e-14 54.7 0.6 1.6e-05 25.1 0.0 3.7 2 2 0 2 2 2 2 Nitroreductase family NifZ PF04319.13 AMK77498.1 - 1.4e-15 56.9 0.1 1.7e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 NifZ domain Fe-S_biosyn PF01521.20 AMK77499.1 - 2e-22 79.5 0.0 2.3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Lin0512_fam PF09585.10 AMK77499.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) NifU_N PF01592.16 AMK77500.1 - 8.8e-50 168.1 0.0 1.9e-49 167.1 0.0 1.6 1 0 0 1 1 1 1 NifU-like N terminal domain NifU PF01106.17 AMK77500.1 - 1.1e-21 76.7 3.2 1e-20 73.6 0.7 2.5 2 0 0 2 2 2 1 NifU-like domain Fer2_BFD PF04324.15 AMK77500.1 - 1.8e-17 63.4 3.2 7.8e-16 58.2 1.5 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Aminotran_5 PF00266.19 AMK77501.1 - 2.1e-90 303.4 0.4 2.5e-90 303.2 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PEP-CTERM PF07589.11 AMK77503.1 - 0.0041 17.1 1.1 0.0072 16.4 1.1 1.4 1 0 0 1 1 1 1 PEP-CTERM motif Lipase_GDSL PF00657.22 AMK77504.1 - 4.9e-09 36.5 0.0 6.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 AMK77504.1 - 0.00072 20.0 7.0 0.0022 18.4 7.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ApoO PF09769.9 AMK77504.1 - 0.18 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein O HMGL-like PF00682.19 AMK77505.1 - 8.4e-81 271.4 2.8 9.9e-81 271.2 2.8 1.0 1 0 0 1 1 1 1 HMGL-like Amidohydro_3 PF07969.11 AMK77505.1 - 0.054 13.0 4.1 0.42 10.0 4.4 1.9 1 1 1 2 2 2 0 Amidohydrolase family Hexapep PF00132.24 AMK77506.1 - 5.8e-13 48.0 11.0 1.6e-08 33.9 2.2 3.2 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AMK77506.1 - 9.9e-07 28.4 10.4 1.4e-06 28.0 3.6 2.9 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 AMK77506.1 - 0.005 17.2 0.0 0.0088 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal TPR_12 PF13424.6 AMK77507.1 - 0.25 11.7 3.7 11 6.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NifW PF03206.14 AMK77508.1 - 7.5e-36 122.6 2.1 8.1e-36 122.5 2.1 1.0 1 0 0 1 1 1 1 Nitrogen fixation protein NifW NifZ PF04319.13 AMK77509.1 - 6.4e-33 112.4 1.1 1.3e-29 101.8 0.4 2.5 2 1 1 3 3 3 2 NifZ domain DUF4926 PF16277.5 AMK77509.1 - 4.1e-06 26.1 0.1 0.0098 15.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4926) UspB PF10625.9 AMK77509.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein B (UspB) Rotamase PF00639.21 AMK77510.1 - 1.4e-22 80.5 0.0 2.9e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AMK77510.1 - 1.9e-19 70.3 0.0 3.5e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AMK77510.1 - 5e-11 43.5 0.0 2.4e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AMK77510.1 - 0.0076 16.1 0.4 0.013 15.3 0.4 1.4 1 0 0 1 1 1 1 SurA N-terminal domain Glyco_hydro_3 PF00933.21 AMK77510.1 - 0.046 13.1 0.1 0.48 9.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 N terminal domain CotJA PF11007.8 AMK77510.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) TraC PF07820.12 AMK77510.1 - 0.16 12.3 1.7 0.27 11.6 0.5 1.9 2 0 0 2 2 2 0 TraC-like protein AAA_2 PF07724.14 AMK77511.1 - 5e-41 140.7 0.0 8.4e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 AMK77511.1 - 2.1e-14 53.3 0.2 5.2e-14 52.1 0.1 1.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AMK77511.1 - 5.2e-13 49.6 0.0 9.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C4_ClpX PF06689.13 AMK77511.1 - 1.6e-10 40.7 0.8 3.2e-10 39.7 0.8 1.6 1 0 0 1 1 1 1 ClpX C4-type zinc finger Mg_chelatase PF01078.21 AMK77511.1 - 1.6e-07 30.9 0.2 0.00014 21.4 0.2 2.6 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 AMK77511.1 - 2.2e-05 23.7 0.1 3.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 AMK77511.1 - 0.0004 20.4 0.1 0.0027 17.7 0.2 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AMK77511.1 - 0.0008 19.1 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 AMK77511.1 - 0.0013 18.5 0.3 0.0073 16.1 0.3 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AMK77511.1 - 0.0038 17.5 0.9 0.04 14.2 0.3 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AMK77511.1 - 0.006 16.3 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 AMK77511.1 - 0.016 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AMK77511.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AMK77511.1 - 0.023 15.1 0.1 0.069 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 AMK77511.1 - 0.024 14.1 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 AMK77511.1 - 0.028 13.7 0.2 0.052 12.8 0.2 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 AMK77511.1 - 0.044 14.0 0.1 0.091 13.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 AMK77511.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 AMK77511.1 - 0.094 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 AMK77511.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 AMK77511.1 - 0.17 10.9 0.2 0.66 9.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 AMK77511.1 - 0.19 11.1 0.2 0.37 10.1 0.2 1.4 1 0 0 1 1 1 0 Isopentenyl transferase Nudix_N_2 PF14803.6 AMK77511.1 - 0.2 11.6 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Nudix N-terminal Glutaredoxin PF00462.24 AMK77512.1 - 2.6e-18 66.0 0.0 3.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin BolA PF01722.18 AMK77512.1 - 1.5e-08 34.8 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Flavodoxin_1 PF00258.25 AMK77513.1 - 2.4e-29 102.4 0.2 2.7e-29 102.2 0.2 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 AMK77513.1 - 7.2e-08 32.8 0.0 1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 AMK77513.1 - 6.2e-05 22.7 0.0 9.9e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin domain RseC_MucC PF04246.12 AMK77514.1 - 1.9e-23 82.8 0.0 2.2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC Ima1_N PF09779.9 AMK77514.1 - 0.09 13.6 0.1 0.12 13.3 0.1 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain BPD_transp_1 PF00528.22 AMK77516.1 - 1.7e-17 63.8 10.7 2.2e-17 63.4 10.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 AMK77517.1 - 7.9e-29 100.9 0.0 1.2e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AMK77517.1 - 9e-15 54.7 0.1 4.6e-14 52.5 0.3 2.1 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 AMK77517.1 - 5e-06 26.5 0.5 0.001 18.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK77517.1 - 2.3e-05 25.0 0.0 3.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AMK77517.1 - 6.5e-05 22.5 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AMK77517.1 - 0.00046 19.9 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK77517.1 - 0.0019 18.6 1.2 0.0051 17.2 1.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain DLIC PF05783.11 AMK77517.1 - 0.0024 16.8 0.0 0.0037 16.2 0.0 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) AAA_25 PF13481.6 AMK77517.1 - 0.0069 16.0 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK77517.1 - 0.0079 16.5 0.1 0.02 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AMK77517.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AMK77517.1 - 0.038 14.1 0.1 0.066 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF4123 PF13503.6 AMK77517.1 - 0.041 14.3 0.7 7.6 7.0 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4123) AAA_13 PF13166.6 AMK77517.1 - 0.047 12.3 0.0 0.22 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AMK77517.1 - 0.051 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AMK77517.1 - 0.066 12.8 0.3 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AMK77517.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain PEPCK_ATP PF01293.20 AMK77517.1 - 0.11 11.1 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA PF00004.29 AMK77517.1 - 0.18 12.3 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TonB_dep_Rec PF00593.24 AMK77518.1 - 9e-36 124.7 7.7 1.9e-35 123.7 7.7 1.5 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK77518.1 - 1.7e-20 73.6 0.0 3.9e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK77518.1 - 1.8e-06 27.2 0.0 3.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family Hyd_WA PF06462.12 AMK77518.1 - 0.027 14.5 0.0 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Propeller Lipocalin_9 PF17186.4 AMK77519.1 - 3.2e-32 111.5 1.0 6.1e-32 110.6 1.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain CrtC PF07143.11 AMK77519.1 - 6e-30 105.1 0.6 1e-29 104.3 0.1 1.6 2 1 0 2 2 2 1 CrtC N-terminal lipocalin domain DUF4154 PF13689.6 AMK77520.1 - 1.3e-37 129.2 0.0 1.6e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like Response_reg PF00072.24 AMK77521.1 - 1.5e-46 157.2 2.2 2.7e-25 88.7 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AMK77521.1 - 2.9e-30 105.0 0.2 6.5e-30 103.9 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK77521.1 - 2.1e-17 62.9 0.4 1.5e-16 60.2 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE8 PF17152.4 AMK77521.1 - 1e-16 61.0 0.0 2.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Periplasmic sensor domain HAMP PF00672.25 AMK77521.1 - 1.6e-11 44.4 1.4 8.2e-11 42.1 1.4 2.4 1 0 0 1 1 1 1 HAMP domain Hpt PF01627.23 AMK77521.1 - 6e-09 36.1 2.0 6e-09 36.1 2.0 3.8 4 0 0 4 4 4 1 Hpt domain HATPase_c_3 PF13589.6 AMK77521.1 - 0.0017 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AMK77521.1 - 0.011 15.5 0.3 0.25 11.1 0.0 2.6 2 1 1 3 3 3 0 Cache domain SBP_bac_3 PF00497.20 AMK77521.1 - 0.058 12.8 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 GGDEF PF00990.21 AMK77522.1 - 6.1e-50 169.1 0.0 1.1e-49 168.2 0.0 1.4 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK77522.1 - 1e-24 86.8 0.1 1.8e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GGDEF_2 PF17853.1 AMK77522.1 - 0.0096 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 GGDEF-like domain Gram_pos_anchor PF00746.21 AMK77522.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SIR2_2 PF13289.6 AMK77523.1 - 7.3e-07 29.4 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 SIR2-like domain DUF5118 PF17162.4 AMK77523.1 - 0.027 14.3 0.2 0.58 10.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5118) adh_short_C2 PF13561.6 AMK77524.1 - 5.7e-63 212.6 1.3 8.1e-63 212.1 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AMK77524.1 - 1.4e-52 178.0 0.9 1.8e-52 177.6 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK77524.1 - 2.3e-10 40.7 3.8 1.6e-09 37.9 3.8 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AMK77524.1 - 0.0016 18.3 0.5 0.0027 17.6 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AMK77524.1 - 0.022 14.1 0.3 0.034 13.5 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AMK77524.1 - 0.026 14.9 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AMK77524.1 - 0.094 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 AMK77524.1 - 0.11 12.5 1.7 0.11 12.4 0.4 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SH3_7 PF12914.7 AMK77525.1 - 0.036 14.2 0.0 0.096 12.9 0.0 1.6 1 1 0 1 1 1 0 SH3 domain of SH3b2 type LPAM_2 PF13627.6 AMK77525.1 - 0.13 12.1 4.0 0.22 11.4 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF520 PF04461.13 AMK77526.1 - 1.4e-64 217.0 6.3 1.6e-64 216.9 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) EXOSC1 PF10447.9 AMK77526.1 - 0.0032 18.0 0.7 0.0054 17.3 0.7 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 RL10P_insert PF17777.1 AMK77526.1 - 0.039 13.9 0.3 0.1 12.6 0.3 1.7 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P DUF2850 PF11012.8 AMK77526.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) Redoxin PF08534.10 AMK77527.1 - 7.1e-09 35.5 0.0 4.2e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AMK77527.1 - 7.2e-06 25.9 0.0 3.3e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family GSHPx PF00255.19 AMK77527.1 - 9.2e-06 25.2 0.1 2e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_2 PF13098.6 AMK77527.1 - 0.02 15.3 0.1 0.91 10.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain PEP-CTERM PF07589.11 AMK77528.1 - 0.018 15.1 1.1 0.018 15.1 1.1 2.4 3 0 0 3 3 3 0 PEP-CTERM motif VPDSG-CTERM PF18205.1 AMK77528.1 - 1.8 8.5 6.9 0.12 12.2 1.0 2.2 2 0 0 2 2 2 0 VPDSG-CTERM motif DUF853 PF05872.12 AMK77529.1 - 2.8e-226 752.0 0.1 3.1e-226 751.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 AMK77529.1 - 9.8e-06 25.8 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain ResIII PF04851.15 AMK77529.1 - 3e-05 24.1 0.0 0.008 16.2 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_10 PF12846.7 AMK77529.1 - 3.8e-05 22.8 0.0 0.039 12.9 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.18 AMK77529.1 - 7.9e-05 22.1 0.1 0.00042 19.7 0.1 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AMK77529.1 - 0.00016 22.0 0.2 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 AMK77529.1 - 0.00036 19.5 0.1 0.0018 17.2 0.1 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 AMK77529.1 - 0.00072 19.3 1.1 0.0014 18.4 0.1 2.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AMK77529.1 - 0.0023 18.3 0.5 0.55 10.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AMK77529.1 - 0.0032 17.9 0.2 1.4 9.3 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AMK77529.1 - 0.0076 16.3 0.0 0.014 15.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 AMK77529.1 - 0.011 15.0 0.2 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 AMK77529.1 - 0.036 13.1 0.1 0.062 12.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_6 PF12774.7 AMK77529.1 - 0.063 12.2 0.3 0.095 11.6 0.3 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 AMK77529.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 AMK77529.1 - 0.079 13.2 0.3 0.24 11.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK77529.1 - 0.097 13.0 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain McyA_C PF12593.8 AMK77529.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal OrfA PF17495.2 AMK77530.1 - 0.043 14.0 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Vpr-like OrfA Pyr_redox_dim PF02852.22 AMK77530.1 - 0.055 13.7 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glyoxalase PF00903.25 AMK77530.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WYL PF13280.6 AMK77531.1 - 6.4e-20 71.9 0.2 3.9e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 WYL domain HTH_11 PF08279.12 AMK77531.1 - 7.9e-19 67.4 1.0 1.2e-18 66.7 0.3 1.7 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 AMK77531.1 - 1e-07 31.6 0.1 1.8e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AMK77531.1 - 0.00054 20.0 0.1 0.0023 18.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_22 PF13309.6 AMK77531.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 HTH domain PuR_N PF09182.10 AMK77531.1 - 0.022 14.7 0.4 0.046 13.7 0.4 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal HTH_31 PF13560.6 AMK77531.1 - 0.024 15.0 0.2 0.076 13.4 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 AMK77531.1 - 0.028 15.0 0.6 0.086 13.5 0.2 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_23 PF13384.6 AMK77531.1 - 0.045 13.6 0.6 0.098 12.5 0.6 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 AMK77531.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.13 AMK77531.1 - 0.072 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain TetR_N PF00440.23 AMK77531.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family PGM_PMM_I PF02878.16 AMK77532.1 - 5.4e-28 97.4 0.0 1e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 AMK77532.1 - 2.8e-13 50.0 0.0 6.5e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AMK77532.1 - 1.2e-09 38.2 0.0 3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 AMK77532.1 - 1.6e-07 31.9 0.0 3.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1690 PF07956.11 AMK77533.1 - 0.53 10.7 5.4 0.66 10.4 5.4 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Spc7 PF08317.11 AMK77533.1 - 1 8.2 5.8 1.1 8.0 5.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GTP_EFTU PF00009.27 AMK77534.1 - 2.5e-44 151.1 0.1 3.8e-44 150.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 AMK77534.1 - 4.6e-07 29.9 0.0 1.5e-05 25.0 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AMK77534.1 - 1.6e-06 28.4 0.1 4e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 AMK77534.1 - 0.00023 21.5 0.1 0.0005 20.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Roc PF08477.13 AMK77534.1 - 0.01 16.1 0.1 3.3 7.9 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 AMK77534.1 - 0.074 12.5 0.1 1.1 8.6 0.0 2.3 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit DUF4062 PF13271.6 AMK77534.1 - 0.11 12.9 0.1 0.69 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) AAA_21 PF13304.6 AMK77536.1 - 1.7e-22 80.7 1.7 5.3e-21 75.7 1.7 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AMK77536.1 - 1.2e-17 64.7 6.0 1.5e-08 34.7 0.6 2.2 1 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AMK77536.1 - 2.5e-06 27.1 0.2 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK77536.1 - 6.8e-05 23.5 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AMK77536.1 - 0.0004 20.9 0.0 0.0018 18.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 AMK77536.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 AMK77536.1 - 0.021 15.3 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AMK77536.1 - 0.03 14.6 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2813 PF11398.8 AMK77536.1 - 0.071 12.4 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_27 PF13514.6 AMK77536.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 AMK77536.1 - 0.1 12.6 0.0 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AMK77536.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 AMK77536.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 AMK77536.1 - 0.25 9.9 1.5 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain PAPS_reduct PF01507.19 AMK77537.1 - 3.5e-65 219.3 0.0 4.3e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glyco_transf_41 PF13844.6 AMK77539.1 - 2.9e-104 349.1 0.0 2.2e-56 191.3 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 Thioredoxin PF00085.20 AMK77540.1 - 1.2e-28 99.1 1.0 8e-28 96.5 0.0 2.4 2 1 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 AMK77540.1 - 3.1e-08 34.0 1.5 1.1e-06 29.1 0.0 3.0 2 2 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 AMK77540.1 - 9.8e-08 32.1 2.1 3e-06 27.3 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_8 PF13905.6 AMK77540.1 - 2.9e-06 27.5 0.1 0.036 14.4 0.0 2.5 2 1 0 3 3 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 AMK77540.1 - 7.1e-05 22.6 0.0 9.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 AMK77540.1 - 0.00018 21.4 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 AMK77540.1 - 0.001 19.0 1.5 0.025 14.6 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin domain HyaE PF07449.11 AMK77540.1 - 0.0043 17.0 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 AMK77540.1 - 0.068 12.5 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family zinc_ribbon_4 PF13717.6 AMK77540.1 - 0.11 12.5 4.2 0.13 12.2 2.9 1.9 2 1 0 2 2 2 0 zinc-ribbon domain Vps36-NZF-N PF16988.5 AMK77540.1 - 0.13 11.7 0.8 0.25 10.8 0.8 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Glutaredoxin PF00462.24 AMK77540.1 - 0.26 11.6 5.4 5.8 7.2 0.1 3.3 2 2 1 3 3 3 0 Glutaredoxin Mu-like_Com PF10122.9 AMK77540.1 - 0.76 9.3 4.5 3.2 7.3 0.1 2.6 2 1 1 3 3 3 0 Mu-like prophage protein Com Zn_ribbon_SprT PF17283.2 AMK77540.1 - 1.1 9.3 6.2 3.5 7.6 6.2 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Peptidase_M48 PF01435.18 AMK77541.1 - 5.4e-29 101.4 0.0 1.7e-28 99.7 0.0 1.8 2 1 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 AMK77541.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 AMK77541.1 - 0.00062 19.6 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 SprT-like family MerR_2 PF13591.6 AMK77542.1 - 2.2e-10 40.2 0.2 2.7e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR_1 PF13411.6 AMK77542.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_17 PF12728.7 AMK77542.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain CSN4_RPN5_eIF3a PF18420.1 AMK77542.1 - 0.1 12.8 0.2 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain DnaJ_C PF01556.18 AMK77543.1 - 5.3e-30 104.5 0.0 6.9e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AMK77543.1 - 9.6e-24 83.3 3.2 1.6e-23 82.6 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain UvrD-helicase PF00580.21 AMK77544.1 - 4.1e-33 115.2 0.0 2.4e-15 56.9 0.2 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AMK77544.1 - 2.1e-30 106.0 0.1 1.4e-29 103.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 AMK77544.1 - 1.4e-22 80.3 0.0 2.2e-19 69.9 0.0 3.0 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK77544.1 - 5.1e-22 78.3 0.0 4e-20 72.2 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UvrD_C PF13361.6 AMK77544.1 - 3.6e-18 66.1 0.0 9.7e-13 48.2 0.0 2.5 1 1 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AMK77544.1 - 2e-13 49.9 0.0 4.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 AMK77544.1 - 2.8e-06 27.2 0.1 0.0011 18.8 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AMK77544.1 - 6.4e-05 22.8 0.2 0.00019 21.2 0.2 1.8 1 0 0 1 1 1 1 AAA domain DUF4194 PF13835.6 AMK77544.1 - 0.0039 17.0 0.4 0.0039 17.0 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4194) GatB_N PF02934.15 AMK77545.1 - 1.9e-114 381.7 0.0 2.5e-114 381.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AMK77545.1 - 6.8e-52 175.3 0.3 6.8e-52 175.3 0.3 1.7 2 0 0 2 2 2 1 GatB domain Uma2 PF05685.12 AMK77546.1 - 3.3e-32 111.4 0.0 3.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease Amidase PF01425.21 AMK77547.1 - 5.3e-157 523.4 0.2 6e-157 523.2 0.2 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 AMK77548.1 - 2.3e-15 56.6 0.2 2.8e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DED PF01335.21 AMK77548.1 - 0.0094 16.2 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 Death effector domain YflT PF11181.8 AMK77548.1 - 0.057 13.9 0.1 0.31 11.6 0.0 2.1 1 1 1 2 2 2 0 Heat induced stress protein YflT Transglut_prok PF09017.10 AMK77548.1 - 0.19 11.1 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Microbial transglutaminase MreB_Mbl PF06723.13 AMK77549.1 - 3.8e-145 482.8 3.2 4.3e-145 482.6 3.2 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 AMK77549.1 - 5.8e-13 47.9 0.0 2e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 AMK77549.1 - 2.4e-10 40.8 1.2 7.8e-10 39.1 0.1 2.1 2 1 0 2 2 2 1 Cell division protein FtsA Actin PF00022.19 AMK77549.1 - 1.3e-07 30.6 0.0 0.00022 20.0 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.8 AMK77549.1 - 3e-07 29.8 0.0 0.0033 16.5 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; EutA PF06277.11 AMK77549.1 - 0.0033 16.3 0.1 0.0052 15.7 0.1 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA DDR PF08841.10 AMK77549.1 - 0.0052 15.8 1.8 0.032 13.2 0.7 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain MreC PF04085.14 AMK77550.1 - 4.7e-35 120.7 0.0 7.1e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 rod shape-determining protein MreC Mito_fiss_reg PF05308.11 AMK77550.1 - 0.052 13.6 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MreD PF04093.12 AMK77551.1 - 1.7e-23 83.5 15.1 2.2e-23 83.1 15.1 1.0 1 0 0 1 1 1 1 rod shape-determining protein MreD Transpeptidase PF00905.22 AMK77552.1 - 1.9e-77 260.5 0.0 3.2e-77 259.8 0.0 1.3 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 AMK77552.1 - 3.8e-44 151.2 0.1 6.2e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain FTSW_RODA_SPOVE PF01098.19 AMK77553.1 - 1.9e-109 366.0 23.5 2.2e-109 365.8 23.5 1.0 1 0 0 1 1 1 1 Cell cycle protein SLT_2 PF13406.6 AMK77554.1 - 3.4e-98 328.5 0.1 3.8e-98 328.3 0.1 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AMK77554.1 - 0.0051 17.3 0.1 0.0092 16.5 0.1 1.7 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT PF01464.20 AMK77554.1 - 0.011 15.4 0.0 0.088 12.5 0.0 2.2 1 1 0 1 1 1 0 Transglycosylase SLT domain MBOAT PF03062.19 AMK77555.1 - 2.7e-25 89.5 11.1 6.3e-25 88.3 10.4 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 AMK77555.1 - 0.0072 16.6 3.8 0.028 14.7 3.7 2.2 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Otopetrin PF03189.13 AMK77555.1 - 6.6 5.4 11.0 0.18 10.6 2.4 2.0 2 0 0 2 2 2 0 Otopetrin FHA PF00498.26 AMK77557.1 - 2.1e-14 53.6 0.0 4.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain SLT PF01464.20 AMK77557.1 - 1.7e-11 43.8 0.0 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Yop-YscD_cpl PF16697.5 AMK77557.1 - 3.5e-11 43.3 0.0 9.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF874 PF05917.11 AMK77557.1 - 0.0025 16.9 0.9 0.0041 16.2 0.9 1.3 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) Atg14 PF10186.9 AMK77557.1 - 0.53 9.3 3.1 0.8 8.7 3.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SpoIIAA-like PF11964.8 AMK77558.1 - 0.0034 18.4 0.1 0.0049 17.9 0.1 1.4 1 1 0 1 1 1 1 SpoIIAA-like Flagellin_N PF00669.20 AMK77560.1 - 8.9e-22 77.7 10.0 8.9e-22 77.7 10.0 2.6 3 1 0 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AMK77560.1 - 6.1e-07 29.7 3.0 6.1e-07 29.7 3.0 3.1 2 2 1 3 3 3 1 Bacterial flagellin C-terminal helical region Big_5 PF13205.6 AMK77560.1 - 0.033 14.9 0.6 0.75 10.5 0.0 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain ABC1 PF03109.16 AMK77560.1 - 0.034 14.3 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 ABC1 family Flg_bbr_C PF06429.13 AMK77561.1 - 1.4e-10 41.2 1.9 6.6e-10 39.0 1.2 2.5 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AMK77561.1 - 1.2e-09 37.9 1.7 6.2e-09 35.6 1.7 2.4 1 0 0 1 1 1 1 Flagella basal body rod protein Glucosaminidase PF01832.20 AMK77562.1 - 8.7e-21 74.2 0.8 1.5e-20 73.5 0.8 1.4 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rod-binding PF10135.9 AMK77562.1 - 1.8e-14 54.0 3.4 6e-14 52.3 3.4 2.0 1 0 0 1 1 1 1 Rod binding protein FlgI PF02119.16 AMK77563.1 - 5.7e-137 456.3 6.9 6.5e-137 456.1 6.9 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein CdiA_C PF18451.1 AMK77563.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain Big_2 PF02368.18 AMK77563.1 - 3.6 7.5 8.7 4.1 7.4 0.3 3.6 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 2) FlgH PF02107.16 AMK77564.1 - 3.5e-59 199.2 0.2 4e-59 199.0 0.2 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein Flg_bbr_C PF06429.13 AMK77565.1 - 3.1e-27 94.5 2.5 3.7e-27 94.3 0.4 2.2 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AMK77565.1 - 2e-15 56.3 0.4 2e-15 56.3 0.4 2.4 2 0 0 2 2 2 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 AMK77566.1 - 1.6e-19 69.8 0.3 4.4e-19 68.4 0.3 1.8 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AMK77566.1 - 3.1e-05 23.8 6.6 0.00011 22.1 6.6 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein FlaE PF07559.14 AMK77567.1 - 1.7e-22 80.3 5.8 1.7e-22 80.3 5.8 2.7 3 1 0 3 3 3 1 Flagellar basal body protein FlaE Flg_bbr_C PF06429.13 AMK77567.1 - 2.3e-17 62.9 0.9 2.3e-17 62.9 0.9 2.2 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AMK77567.1 - 8.8e-11 41.5 8.2 3.1e-10 39.7 8.2 2.1 1 0 0 1 1 1 1 Flagella basal body rod protein Strep_pep PF14404.6 AMK77567.1 - 0.15 12.4 1.4 0.37 11.1 0.2 2.4 3 0 0 3 3 3 0 Ribosomally synthesized peptide in Streptomyces species FlgD PF03963.14 AMK77568.1 - 7.3e-23 80.7 3.8 1.5e-22 79.7 3.8 1.5 1 0 0 1 1 1 1 Flagellar hook capping protein - N-terminal region FlgD_ig PF13860.6 AMK77568.1 - 1.1e-17 63.6 1.9 1.8e-17 63.0 0.3 2.0 2 0 0 2 2 2 1 FlgD Ig-like domain FLgD_tudor PF13861.6 AMK77568.1 - 4.2e-15 55.7 0.0 1.5e-14 53.9 0.0 1.9 2 1 0 2 2 2 1 FlgD Tudor-like domain DUF2271 PF10029.9 AMK77568.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) FlaG PF03646.15 AMK77568.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 FlaG protein DNA_ligase_aden PF01653.18 AMK77568.1 - 0.026 13.6 0.2 0.046 12.8 0.1 1.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase adenylation domain Flg_bbr_C PF06429.13 AMK77569.1 - 6.4e-12 45.4 6.2 1.2e-11 44.5 5.6 1.9 1 1 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 AMK77569.1 - 1e-05 25.4 3.2 1e-05 25.4 3.2 2.2 2 0 0 2 2 2 1 Flagella basal body rod protein Band_7 PF01145.25 AMK77569.1 - 0.06 13.3 0.5 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 SPFH domain / Band 7 family Flg_bb_rod PF00460.20 AMK77570.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Flagella basal body rod protein CheR PF01739.18 AMK77571.1 - 7.4e-58 195.3 0.0 9.9e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AMK77571.1 - 1.6e-11 43.7 0.0 4.5e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AMK77571.1 - 5.8e-08 33.3 0.0 4.5e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK77571.1 - 8.7e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77571.1 - 6.9e-07 29.9 0.0 4.7e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK77571.1 - 1.4e-06 28.2 0.3 0.00058 19.7 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77571.1 - 4.2e-06 27.3 0.1 0.00022 21.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 AMK77571.1 - 0.084 12.5 0.1 0.28 10.8 0.1 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 AMK77571.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB CheW PF01584.19 AMK77572.1 - 1.2e-35 122.1 0.4 2e-35 121.4 0.4 1.3 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 AMK77572.1 - 6.7e-17 61.7 0.3 1.1e-16 61.0 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Lipase_GDSL_lke PF16255.5 AMK77572.1 - 0.16 11.3 0.4 3 7.1 0.2 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase ChapFlgA PF13144.6 AMK77573.1 - 1e-31 109.6 6.4 1.4e-31 109.1 6.4 1.2 1 0 0 1 1 1 1 Chaperone for flagella basal body P-ring formation ChapFlgA_N PF17656.1 AMK77573.1 - 2e-17 63.1 0.0 4.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 FlgA N-terminal domain SAF PF08666.12 AMK77573.1 - 3.9e-07 30.6 0.5 7.9e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 SAF domain FlgM PF04316.13 AMK77574.1 - 1.4e-18 66.9 4.6 2.5e-18 66.2 4.6 1.4 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM DUF2072 PF09845.9 AMK77574.1 - 0.041 14.1 0.1 0.05 13.9 0.1 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein FlgN PF05130.12 AMK77575.1 - 9e-21 74.9 5.5 1e-20 74.7 5.5 1.1 1 0 0 1 1 1 1 FlgN protein DUF2959 PF11172.8 AMK77575.1 - 0.062 13.4 1.9 0.086 13.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) YcgR PF07317.12 AMK77576.1 - 3.3e-18 65.5 0.0 6.7e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Flagellar regulator YcgR PilZ PF07238.14 AMK77576.1 - 4.3e-07 30.2 0.1 7.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 PilZ domain Histone_HNS PF00816.21 AMK77577.1 - 1.8e-24 86.4 2.4 2e-24 86.2 2.4 1.0 1 0 0 1 1 1 1 H-NS histone family GreA_GreB_N PF03449.15 AMK77577.1 - 0.02 15.1 2.3 0.03 14.5 2.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal DUF3573 PF12097.8 AMK77577.1 - 0.022 13.6 0.4 0.027 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1192 PF06698.11 AMK77577.1 - 0.029 14.4 5.5 0.13 12.4 5.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) HalX PF08663.10 AMK77577.1 - 0.054 13.8 1.5 0.088 13.1 1.5 1.3 1 0 0 1 1 1 0 HalX domain TSC22 PF01166.18 AMK77577.1 - 0.072 13.4 1.0 0.14 12.5 1.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 AMK77577.1 - 0.13 12.1 4.1 0.25 11.1 4.1 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF2937 PF11157.8 AMK77577.1 - 0.15 11.7 0.2 0.19 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FlxA PF14282.6 AMK77577.1 - 2.4 8.2 9.5 2.2 8.3 2.8 2.1 1 1 1 2 2 2 0 FlxA-like protein ResIII PF04851.15 AMK77581.1 - 0.0056 16.7 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CO_dh PF02552.16 AMK77581.1 - 0.08 12.7 1.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Phage_integrase PF00589.22 AMK77582.1 - 5e-30 104.5 0.4 8.6e-30 103.8 0.4 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_2 PF12834.7 AMK77582.1 - 0.0041 17.8 0.1 0.018 15.7 0.1 2.1 1 0 0 1 1 1 1 Phage integrase, N-terminal Arm-DNA-bind_4 PF14657.6 AMK77582.1 - 0.0059 16.3 0.3 0.012 15.4 0.3 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain Arm-DNA-bind_2 PF12167.8 AMK77582.1 - 0.025 14.5 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain Recombinase PF07508.13 AMK77583.1 - 1.3e-11 44.8 0.0 1.9e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Recombinase Epimerase PF01370.21 AMK77585.1 - 1.4e-06 28.0 0.0 3.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 AMK77585.1 - 0.0003 20.7 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AMK77585.1 - 0.0003 20.0 0.0 0.0017 17.6 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 AMK77585.1 - 0.00037 20.2 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 AMK77585.1 - 0.0064 16.7 0.0 0.0099 16.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 AMK77585.1 - 0.01 16.0 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 AMK77585.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AMK77585.1 - 0.043 14.4 0.0 0.071 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 AMK77585.1 - 0.044 14.4 0.0 0.071 13.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3710 PF12502.8 AMK77585.1 - 0.061 13.0 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) UDPG_MGDP_dh_N PF03721.14 AMK77585.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 AMK77585.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 AMK77585.1 - 0.26 10.3 0.0 0.55 9.2 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family B12-binding PF02310.19 AMK77586.1 - 1.4e-11 44.4 0.0 5e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain Radical_SAM PF04055.21 AMK77586.1 - 2.8e-11 44.1 0.0 6.8e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily DUF4080 PF13311.6 AMK77586.1 - 2.9e-10 40.7 0.0 4.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4080) TPR_19 PF14559.6 AMK77587.1 - 0.00013 22.4 9.7 0.063 13.8 2.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK77587.1 - 0.00034 21.2 1.5 0.49 11.3 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AMK77587.1 - 0.00035 20.5 0.5 0.79 10.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat LysM PF01476.20 AMK77587.1 - 0.0014 18.6 0.2 0.0031 17.5 0.2 1.6 1 0 0 1 1 1 1 LysM domain TPR_2 PF07719.17 AMK77587.1 - 0.0038 17.2 0.3 0.18 12.0 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 AMK77587.1 - 0.018 15.7 6.9 0.17 12.6 1.8 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 AMK77587.1 - 0.027 14.8 2.3 5.9 7.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AMK77587.1 - 0.091 12.6 0.5 1.3 8.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 AMK77587.1 - 0.099 12.9 0.4 4.4 7.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK77587.1 - 0.15 12.0 0.5 24 5.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 AMK77587.1 - 0.32 11.3 3.1 2.2 8.6 3.1 2.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain FAM76 PF16046.5 AMK77587.1 - 3.1 7.1 4.5 5.5 6.3 4.5 1.3 1 0 0 1 1 1 0 FAM76 protein Semialdhyde_dhC PF02774.18 AMK77588.1 - 2.5e-61 207.0 0.0 3.3e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AMK77588.1 - 3.4e-33 114.6 0.0 7.2e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 AMK77588.1 - 0.044 13.4 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain RAP-1 PF03085.15 AMK77588.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Iso_dh PF00180.20 AMK77589.1 - 1.2e-139 465.3 0.0 1.4e-139 465.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF166 PF02593.14 AMK77589.1 - 0.036 13.6 0.0 0.15 11.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function Cytochrom_B559a PF00284.20 AMK77589.1 - 0.052 13.3 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Aconitase_C PF00694.19 AMK77590.1 - 1.8e-36 125.3 0.0 2.5e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AMK77590.1 - 0.033 13.8 0.0 4 7.0 0.0 2.1 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus Aconitase PF00330.20 AMK77591.1 - 5.3e-153 510.3 0.1 6.1e-153 510.1 0.1 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) ADK PF00406.22 AMK77592.1 - 5.9e-57 192.0 0.0 7e-57 191.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AMK77592.1 - 2.6e-26 92.7 0.8 4e-26 92.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 AMK77592.1 - 1.4e-18 66.6 0.1 3.3e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 AMK77592.1 - 9.2e-05 23.0 0.0 0.00018 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 AMK77592.1 - 0.0011 19.3 0.2 1.1 9.5 0.1 2.4 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 AMK77592.1 - 0.076 13.2 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain RrnaAD PF00398.20 AMK77593.1 - 1.3e-67 227.7 0.0 1.5e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AMK77593.1 - 0.0041 17.8 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK77593.1 - 0.0083 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77593.1 - 0.05 14.3 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PdxA PF04166.12 AMK77594.1 - 2.3e-107 358.6 0.0 2.6e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA MarR_2 PF12802.7 AMK77595.1 - 3.6e-10 39.6 0.0 6.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AMK77595.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AMK77595.1 - 1.3e-05 25.6 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 AMK77595.1 - 0.00015 21.6 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 AMK77595.1 - 0.00051 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AMK77595.1 - 0.00073 19.5 0.0 0.0018 18.2 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 AMK77595.1 - 0.00085 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AMK77595.1 - 0.0028 17.2 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Crp PF00325.20 AMK77595.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family LexA_DNA_bind PF01726.16 AMK77595.1 - 0.017 14.9 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 LexA DNA binding domain Fe_dep_repress PF01325.19 AMK77595.1 - 0.018 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AMK77595.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RecR PF02132.15 AMK77595.1 - 0.88 9.2 3.9 0.39 10.3 0.8 2.1 2 1 0 2 2 2 0 RecR protein Cytochrom_D1 PF02239.16 AMK77596.1 - 7.8e-46 156.3 0.1 1.1e-45 155.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Cytochrome_CBB3 PF13442.6 AMK77596.1 - 4.4e-10 39.7 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK77596.1 - 0.00033 21.7 0.6 0.012 16.7 0.3 2.7 2 1 0 2 2 2 1 Cytochrome c DUF4221 PF13970.6 AMK77596.1 - 0.038 13.5 0.0 2.6 7.5 0.0 3.4 3 1 2 5 5 5 0 Domain of unknown function (DUF4221) Cytochrome_CBB3 PF13442.6 AMK77597.1 - 3e-08 33.9 0.0 4.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK77597.1 - 9.2e-07 29.9 0.2 8.3e-06 26.9 0.2 2.0 1 1 0 1 1 1 1 Cytochrome c 4HFCP_synth PF04476.13 AMK77597.1 - 0.062 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 4-HFC-P synthase DUF2059 PF09832.9 AMK77597.1 - 0.15 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) Cytochrome_CBB3 PF13442.6 AMK77598.1 - 1.8e-08 34.6 0.0 2.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK77598.1 - 0.043 15.0 0.8 2.4 9.4 0.8 2.2 1 1 0 1 1 1 0 Cytochrome c Cytochrom_D1 PF02239.16 AMK77599.1 - 5.7e-112 373.9 0.0 6.6e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome D1 heme domain Lactonase PF10282.9 AMK77599.1 - 0.00037 19.8 0.0 0.037 13.3 0.0 2.7 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller AsnC_trans_reg2 PF17805.1 AMK77600.1 - 5e-19 68.2 0.1 1.6e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AMK77600.1 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 AMK77600.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 AMK77600.1 - 0.093 12.4 0.0 0.29 10.9 0.0 1.8 1 1 1 2 2 2 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 AMK77600.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GntR PF00392.21 AMK77600.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_47 PF16221.5 AMK77600.1 - 0.15 11.6 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 winged helix-turn-helix HTH_36 PF13730.6 AMK77600.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain AsnC_trans_reg2 PF17805.1 AMK77601.1 - 3.2e-24 84.9 0.1 6.9e-24 83.8 0.0 1.5 2 0 0 2 2 2 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AMK77601.1 - 3.9e-08 33.0 0.4 7.5e-08 32.1 0.4 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AMK77601.1 - 0.018 14.6 0.2 0.04 13.5 0.2 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AMK77601.1 - 0.026 14.5 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain AsnC_trans_reg2 PF17805.1 AMK77602.1 - 2.2e-22 79.0 0.0 3.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AMK77602.1 - 9.5e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain DUF5601 PF18151.1 AMK77602.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) AsnC_trans_reg2 PF17805.1 AMK77603.1 - 3.4e-27 94.4 0.0 7.6e-27 93.3 0.0 1.6 2 0 0 2 2 2 1 AsnC-like ligand binding domain HTH_AsnC-type PF13404.6 AMK77603.1 - 1.4e-08 34.4 1.3 3.8e-08 33.0 0.0 2.3 2 1 1 3 3 3 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AMK77603.1 - 1.2e-05 24.8 0.1 0.00053 19.5 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MIase PF02426.16 AMK77603.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 Muconolactone delta-isomerase HTH_11 PF08279.12 AMK77603.1 - 0.015 15.2 0.1 0.061 13.3 0.0 2.0 2 1 1 3 3 3 0 HTH domain MarR_2 PF12802.7 AMK77603.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 MarR family GerE PF00196.19 AMK77603.1 - 0.08 12.5 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Med25_SD1 PF11235.8 AMK77603.1 - 0.084 13.2 0.1 0.084 13.2 0.1 1.6 2 1 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 HTH_20 PF12840.7 AMK77603.1 - 0.15 12.1 0.1 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Radical_SAM PF04055.21 AMK77604.1 - 4.3e-19 69.5 0.0 6.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AMK77604.1 - 1.1e-09 38.6 0.0 3e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AMK77604.1 - 1e-07 32.1 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 AMK77604.1 - 0.0069 16.9 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain His_Phos_1 PF00300.22 AMK77606.1 - 7.7e-11 42.0 0.0 3.3e-09 36.7 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Fe-S_biosyn PF01521.20 AMK77607.1 - 3.8e-21 75.4 0.0 4.4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis AnmK PF03702.14 AMK77608.1 - 2e-144 481.2 0.0 2.3e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Peptidase_M23 PF01551.22 AMK77609.1 - 4.6e-30 103.7 4.3 1.2e-29 102.4 3.2 2.2 2 1 1 3 3 3 1 Peptidase family M23 OapA PF04225.12 AMK77609.1 - 5.6e-08 32.8 0.1 6.6e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 Opacity-associated protein A LysM-like domain TOBE PF03459.17 AMK77609.1 - 0.0029 17.8 0.0 6.2 7.2 0.0 3.5 3 0 0 3 3 3 2 TOBE domain LysM PF01476.20 AMK77609.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 LysM domain tRNA-synt_1b PF00579.25 AMK77610.1 - 6.7e-80 268.5 0.0 8.5e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AMK77610.1 - 5.6e-10 38.8 0.0 1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 AMK77610.1 - 3.7e-05 23.5 0.0 7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4_2 PF13275.6 AMK77610.1 - 0.0031 17.3 0.1 0.0076 16.0 0.1 1.6 1 0 0 1 1 1 1 S4 domain AhpC-TSA PF00578.21 AMK77611.1 - 4.2e-23 81.6 0.0 4.9e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK77611.1 - 5.3e-23 81.4 0.0 6.6e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AMK77611.1 - 2.3e-09 37.5 0.0 3.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 AMK77611.1 - 1.2e-06 28.9 0.0 2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain GSHPx PF00255.19 AMK77611.1 - 5.8e-05 22.6 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase SCO1-SenC PF02630.14 AMK77611.1 - 0.00018 21.4 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin PF00085.20 AMK77611.1 - 0.0011 18.9 0.0 0.0089 16.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin TraF PF13728.6 AMK77611.1 - 0.0015 18.4 0.0 0.0048 16.7 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 AMK77611.1 - 0.03 14.5 0.0 0.074 13.2 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA_2 PF13911.6 AMK77611.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme 2-Hacid_dh_C PF02826.19 AMK77612.1 - 1.5e-64 216.6 0.0 3.4e-64 215.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AMK77612.1 - 8.1e-37 125.9 1.9 1.7e-36 124.8 0.3 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 AMK77612.1 - 2.4e-08 33.6 0.2 7e-08 32.1 0.2 1.9 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 AMK77612.1 - 6.7e-05 23.0 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT_6 PF13740.6 AMK77612.1 - 0.0023 17.9 0.3 0.0069 16.4 0.3 1.8 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 AMK77612.1 - 0.0051 16.4 0.1 0.37 10.3 0.0 2.8 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT_4 PF13291.6 AMK77612.1 - 0.11 13.1 0.4 0.4 11.3 0.4 1.9 1 0 0 1 1 1 0 ACT domain Hydrolase PF00702.26 AMK77613.1 - 1.2e-09 38.8 0.0 1.8e-08 35.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK77613.1 - 1.7e-09 38.4 0.2 3.3e-09 37.4 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AMK77613.1 - 6.8e-05 23.0 0.0 0.00064 19.9 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK77613.1 - 0.068 12.9 0.0 7.7 6.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Transcrip_reg PF01709.20 AMK77614.1 - 4.5e-96 320.9 0.8 5.1e-96 320.7 0.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator Ribosomal_S9 PF00380.19 AMK77614.1 - 0.12 12.9 0.1 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S9/S16 RuvC PF02075.17 AMK77615.1 - 7.3e-61 204.4 0.1 8.4e-61 204.2 0.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF3882 PF07066.11 AMK77615.1 - 0.004 17.3 0.0 0.0048 17.0 0.0 1.3 1 1 0 1 1 1 1 Lactococcus phage M3 protein RuvA_N PF01330.21 AMK77616.1 - 3.1e-24 84.9 0.0 3.3e-23 81.6 0.0 2.3 2 0 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 AMK77616.1 - 1.6e-16 60.7 0.0 4.4e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 AMK77616.1 - 3.4e-11 43.4 0.0 6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 AMK77616.1 - 6.9e-08 32.0 2.2 0.0036 17.1 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_2 PF12826.7 AMK77616.1 - 0.0056 16.7 0.0 12 6.1 0.0 3.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 AMK77616.1 - 0.012 15.9 0.2 0.82 10.1 0.1 2.5 2 0 0 2 2 2 0 IMS family HHH motif HHH_3 PF12836.7 AMK77616.1 - 0.014 15.6 0.0 1.7 8.9 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AMK77616.1 - 0.02 15.5 0.0 2.3 8.9 0.0 2.4 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.9 AMK77616.1 - 0.11 12.4 0.0 24 4.8 0.0 3.0 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 AMK77616.1 - 0.15 12.5 0.0 7.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 AMK77616.1 - 0.16 12.3 0.0 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family RuvB_N PF05496.12 AMK77617.1 - 3.1e-83 277.3 0.2 8.9e-83 275.8 0.1 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AMK77617.1 - 4.7e-33 112.8 0.3 1.1e-32 111.6 0.3 1.7 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AMK77617.1 - 4.2e-26 90.6 0.0 8.6e-26 89.6 0.0 1.6 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AMK77617.1 - 4.2e-20 72.5 0.0 1.1e-19 71.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK77617.1 - 1.2e-08 35.0 0.0 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AMK77617.1 - 1e-05 25.0 0.0 0.033 13.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AMK77617.1 - 2.3e-05 24.3 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK77617.1 - 3.2e-05 24.4 0.2 0.0092 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AMK77617.1 - 3.4e-05 24.1 0.2 0.049 13.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain Sigma54_activat PF00158.26 AMK77617.1 - 3.5e-05 23.6 0.0 0.28 10.9 0.0 2.3 1 1 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 AMK77617.1 - 4.6e-05 22.8 0.3 0.00093 18.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain T2SSE PF00437.20 AMK77617.1 - 0.00047 19.3 0.0 0.0012 18.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.15 AMK77617.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 AMK77617.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 AMK77617.1 - 0.0017 17.6 0.0 0.079 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 AMK77617.1 - 0.0042 17.0 0.1 0.096 12.6 0.0 2.4 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.6 AMK77617.1 - 0.0043 17.6 0.0 0.011 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 AMK77617.1 - 0.0079 15.6 0.1 0.47 9.8 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 AMK77617.1 - 0.0098 16.3 0.0 0.026 14.9 0.0 1.7 2 0 0 2 2 1 1 RNA helicase MCM PF00493.23 AMK77617.1 - 0.014 14.5 0.0 0.98 8.5 0.0 2.3 1 1 0 1 1 1 0 MCM P-loop domain AAA_19 PF13245.6 AMK77617.1 - 0.015 15.6 0.4 0.44 10.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AMK77617.1 - 0.016 15.0 1.4 0.072 12.8 0.1 2.4 2 1 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 AMK77617.1 - 0.021 14.0 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 AMK77617.1 - 0.038 13.7 0.1 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AMK77617.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 AMK77617.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AMK77617.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 AMK77617.1 - 0.075 13.0 0.0 3.3 7.7 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 AMK77617.1 - 0.085 12.7 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_17 PF13207.6 AMK77617.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 AMK77617.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 AMK77617.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 AMK77617.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase 4HBT PF03061.22 AMK77618.1 - 8.5e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 AMK77618.1 - 7.5e-15 55.5 0.1 8.3e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 AMK77618.1 - 6.1e-07 29.0 0.0 6.7e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Acyl-ACP thioesterase MotA_ExbB PF01618.16 AMK77619.1 - 2e-41 140.7 0.0 2.8e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AMK77620.1 - 2.7e-26 92.2 0.4 3.2e-26 92.0 0.4 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 AMK77621.1 - 4.2e-12 46.1 0.0 1.4e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 TonB C terminal TonB_C PF03544.14 AMK77621.1 - 6.1e-08 33.0 2.5 7e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal PD40 PF07676.12 AMK77622.1 - 4.8e-45 150.6 9.8 3.2e-14 52.4 0.2 6.1 6 0 0 6 6 6 5 WD40-like Beta Propeller Repeat TolB_N PF04052.13 AMK77622.1 - 2.4e-26 92.0 0.0 7e-26 90.5 0.0 1.8 2 0 0 2 2 2 1 TolB amino-terminal domain DPPIV_N PF00930.21 AMK77622.1 - 1.1e-09 37.5 0.0 0.00088 18.1 0.0 3.5 1 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.6 AMK77622.1 - 1.4e-09 37.1 0.0 0.079 11.6 0.0 5.0 2 2 2 5 5 5 4 Oligogalacturonate lyase Gmad1 PF10647.9 AMK77622.1 - 3.1e-08 33.7 0.1 0.018 14.8 0.0 3.5 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain SGL PF08450.12 AMK77622.1 - 0.029 13.9 0.0 1.6 8.3 0.0 2.5 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region OmpA PF00691.20 AMK77623.1 - 9.7e-19 67.5 0.1 1.5e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 OmpA family DUF2957 PF11170.8 AMK77623.1 - 0.037 12.9 0.2 0.048 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) Serglycin PF04360.12 AMK77623.1 - 7.8 6.4 9.6 41 4.1 9.9 2.1 1 1 1 2 2 2 0 Serglycin TPR_6 PF13174.6 AMK77624.1 - 1.8e-17 62.7 2.8 1.7e-05 25.1 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK77624.1 - 3.2e-16 59.7 1.6 1.5e-09 38.4 0.5 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TolA_bind_tri PF16331.5 AMK77624.1 - 2.5e-13 49.9 4.0 4.4e-13 49.1 4.0 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_14 PF13428.6 AMK77624.1 - 1.9e-12 46.9 1.0 0.0017 19.0 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat YfiO PF13525.6 AMK77624.1 - 3.3e-12 46.6 2.9 6.5e-11 42.3 2.9 2.2 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_2 PF07719.17 AMK77624.1 - 1.6e-09 37.2 0.4 0.0021 18.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 AMK77624.1 - 1.2e-07 32.1 2.3 4.1e-05 24.0 0.2 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 AMK77624.1 - 2.4e-07 30.4 0.1 0.022 14.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_18 PF13512.6 AMK77624.1 - 6.6e-07 29.6 2.8 4.7e-06 26.8 2.2 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 AMK77624.1 - 3.8e-06 26.5 0.1 0.015 15.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 AMK77624.1 - 0.00019 21.7 0.1 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 AMK77624.1 - 0.00022 21.0 3.0 0.00022 21.0 3.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain SlyX PF04102.12 AMK77624.1 - 0.017 15.7 1.5 0.04 14.5 1.5 1.6 1 0 0 1 1 1 0 SlyX TPR_17 PF13431.6 AMK77624.1 - 0.035 14.5 0.5 3.7 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.7 AMK77624.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Tropomyosin like DASH_Spc34 PF08657.10 AMK77624.1 - 0.067 13.0 0.6 0.14 12.0 0.1 1.7 2 1 0 2 2 1 0 DASH complex subunit Spc34 IFT20 PF14931.6 AMK77624.1 - 0.07 13.3 0.4 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Tektin PF03148.14 AMK77624.1 - 0.08 11.7 0.4 0.12 11.1 0.4 1.2 1 0 0 1 1 1 0 Tektin family DUF1664 PF07889.12 AMK77624.1 - 0.082 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ANAPC3 PF12895.7 AMK77624.1 - 0.085 13.1 3.0 0.15 12.3 0.3 2.4 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin_2 PF14523.6 AMK77624.1 - 0.094 13.1 1.2 7 7.1 0.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Docking PF08990.11 AMK77624.1 - 0.16 11.6 1.5 0.18 11.5 0.3 1.8 2 0 0 2 2 2 0 Erythronolide synthase docking CCDC53 PF10152.9 AMK77624.1 - 0.85 10.0 4.0 1.5 9.2 4.0 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex MscS_porin PF12795.7 AMK77624.1 - 0.85 9.1 9.6 4.5 6.7 5.4 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Radical_SAM PF04055.21 AMK77625.1 - 4.5e-13 49.9 0.0 6.1e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AMK77625.1 - 4.6e-10 39.6 0.0 8.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK77625.1 - 1.2e-06 28.8 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain zf-CHCC PF10276.9 AMK77625.1 - 0.032 14.3 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger domain QueC PF06508.13 AMK77626.1 - 5.3e-79 264.6 0.0 6e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AMK77626.1 - 1e-07 31.9 0.1 1.4e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 AMK77626.1 - 0.00027 20.6 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 2 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 AMK77626.1 - 0.0013 18.5 0.0 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 PP-loop family PAPS_reduct PF01507.19 AMK77626.1 - 0.19 11.7 0.0 0.69 9.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family MCPsignal PF00015.21 AMK77627.1 - 8.1e-06 25.8 13.9 7.4e-05 22.6 4.5 2.1 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Lactamase_B PF00753.27 AMK77628.1 - 5e-19 69.1 0.7 6.2e-19 68.8 0.7 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Radical_SAM PF04055.21 AMK77629.1 - 4.2e-30 105.3 0.0 7.2e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 AMK77629.1 - 1.1e-27 95.9 0.0 2.1e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AMK77629.1 - 7.7e-17 61.0 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 TRAM domain B12-binding PF02310.19 AMK77629.1 - 0.075 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain TRAM_2 PF18693.1 AMK77629.1 - 0.11 12.6 0.0 0.62 10.3 0.0 2.1 1 1 0 1 1 1 0 TRAM domain PhoH PF02562.16 AMK77630.1 - 3.8e-94 313.9 0.0 5.4e-94 313.4 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 AMK77630.1 - 1.9e-09 37.5 0.0 5.8e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AMK77630.1 - 0.00023 21.5 0.0 0.00073 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AMK77630.1 - 0.0025 17.6 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.12 AMK77630.1 - 0.0059 16.3 0.2 0.27 10.8 0.0 2.8 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) DEAD PF00270.29 AMK77630.1 - 0.02 14.7 0.1 0.85 9.4 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 AMK77630.1 - 0.027 14.7 0.3 0.34 11.2 0.3 2.5 1 1 0 1 1 1 0 AAA domain HIRAN PF08797.11 AMK77630.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain DUF2292 PF10055.9 AMK77630.1 - 0.032 13.9 0.1 0.21 11.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) AAA PF00004.29 AMK77630.1 - 0.13 12.7 0.1 0.45 11.0 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0054 PF02130.17 AMK77631.1 - 5.4e-37 126.5 0.0 6e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 CorC_HlyC PF03471.17 AMK77632.1 - 3e-23 81.6 1.0 1.1e-22 79.8 0.0 2.3 3 0 0 3 3 3 1 Transporter associated domain CBS PF00571.28 AMK77632.1 - 4.7e-13 49.4 7.6 2.6e-06 27.8 0.5 2.8 3 0 0 3 3 3 2 CBS domain zf-ZPR1 PF03367.13 AMK77632.1 - 0.051 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 ZPR1 zinc-finger domain EAL PF00563.20 AMK77633.1 - 1e-72 244.5 1.5 1.3e-71 240.9 0.0 2.9 3 0 0 3 3 3 1 EAL domain GGDEF PF00990.21 AMK77633.1 - 1.5e-55 187.3 0.8 8.1e-55 185.0 0.4 2.5 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS PF00989.25 AMK77633.1 - 1e-24 86.7 0.3 5.3e-11 42.5 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AMK77633.1 - 9.4e-20 70.9 0.0 6.3e-11 42.5 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AMK77633.1 - 1.1e-18 67.4 0.1 1.7e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AMK77633.1 - 1.9e-18 66.0 2.5 8.9e-09 35.2 0.1 4.3 3 2 0 3 3 3 2 PAS domain GAF_2 PF13185.6 AMK77633.1 - 2e-13 50.9 0.7 8.6e-13 48.8 0.2 2.5 3 0 0 3 3 3 1 GAF domain PAS_3 PF08447.12 AMK77633.1 - 1.4e-12 47.8 0.1 5.6e-08 33.0 0.0 3.5 4 0 0 4 4 4 2 PAS fold dCache_1 PF02743.18 AMK77633.1 - 7.7e-12 45.5 0.1 2.8e-10 40.4 0.1 3.0 3 0 0 3 3 3 1 Cache domain GAF PF01590.26 AMK77633.1 - 2e-07 31.7 0.0 8.6e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 GAF domain PAS_7 PF12860.7 AMK77633.1 - 9.2e-06 25.8 0.4 0.015 15.4 0.0 3.2 2 1 0 2 2 2 2 PAS fold HAMP PF00672.25 AMK77633.1 - 0.00044 20.6 0.0 0.00088 19.6 0.0 1.6 1 0 0 1 1 1 1 HAMP domain dCache_3 PF14827.6 AMK77633.1 - 0.01 15.5 0.0 0.57 9.8 0.0 3.2 3 0 0 3 3 3 0 Double sensory domain of two-component sensor kinase Autoind_bind PF03472.15 AMK77633.1 - 0.048 13.1 0.2 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Autoinducer binding domain SBP_bac_8 PF13416.6 AMK77634.1 - 6.4e-32 111.5 0.0 7.8e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AMK77634.1 - 4.3e-24 85.3 0.0 5.7e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AMK77634.1 - 8e-11 42.4 0.0 3e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 AMK77634.1 - 1.4e-07 31.5 0.1 3.1e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Secretin PF00263.21 AMK77635.1 - 1.1e-08 35.0 0.3 2.1e-08 34.0 0.3 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AMK77635.1 - 1.2e-05 25.6 0.2 0.00012 22.4 0.2 2.5 1 1 0 1 1 1 1 Bacterial type II/III secretion system short domain Glyco_transf_5 PF08323.11 AMK77636.1 - 5.3e-78 262.1 0.0 5.5e-76 255.5 0.0 2.1 2 0 0 2 2 2 2 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 AMK77636.1 - 1.6e-11 44.0 0.0 2.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK77636.1 - 1.4e-07 31.7 0.0 6.1e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 AMK77636.1 - 2e-07 31.5 0.0 3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK77636.1 - 2.4e-06 28.1 0.0 9.4e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain CBM_48 PF02922.18 AMK77637.1 - 3.1e-23 81.9 0.1 4.4e-22 78.2 0.0 2.7 2 1 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 AMK77637.1 - 2.2e-20 72.9 0.0 5.2e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 AMK77637.1 - 4e-17 62.8 1.0 9.1e-12 45.2 0.1 2.8 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 AMK77637.1 - 0.2 9.8 0.0 0.47 8.6 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Glyco_hydro_57 PF03065.15 AMK77638.1 - 4.7e-67 226.5 0.0 6.4e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DnaG_DnaB_bind PF08278.11 AMK77638.1 - 0.18 12.4 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Glyco_hydro_77 PF02446.17 AMK77639.1 - 1.2e-154 515.7 0.8 1.4e-154 515.5 0.8 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase SBP_bac_3 PF00497.20 AMK77640.1 - 8.5e-09 35.2 0.0 6.8e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 PQQ PF01011.21 AMK77641.1 - 6.5e-37 123.7 15.8 5e-08 32.5 0.0 7.7 7 0 0 7 7 7 6 PQQ enzyme repeat PQQ_2 PF13360.6 AMK77641.1 - 2.1e-24 86.5 15.5 9.8e-18 64.6 0.0 3.9 4 1 0 4 4 4 3 PQQ-like domain PQQ_3 PF13570.6 AMK77641.1 - 7.2e-12 45.4 20.8 0.00034 21.0 0.4 7.2 8 0 0 8 8 8 4 PQQ-like domain DUF4905 PF16248.5 AMK77641.1 - 0.12 12.2 1.3 14 5.6 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4905) PMSR PF01625.21 AMK77642.1 - 5.8e-62 208.4 2.4 7e-62 208.1 2.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HSP33 PF01430.19 AMK77643.1 - 1.1e-78 264.4 0.6 1.2e-78 264.2 0.6 1.0 1 0 0 1 1 1 1 Hsp33 protein DUF1318 PF07027.12 AMK77645.1 - 1.1e-27 96.3 0.4 1.2e-27 96.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) PG_binding_3 PF09374.10 AMK77645.1 - 0.07 13.4 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Lipoprotein_19 PF13617.6 AMK77646.1 - 1.6e-18 66.2 3.0 2.1e-18 65.8 3.0 1.2 1 0 0 1 1 1 1 YnbE-like lipoprotein DctA-YdbH PF11739.8 AMK77647.1 - 3.5e-40 137.9 4.4 5.9e-40 137.2 1.4 2.7 1 1 2 3 3 3 1 Dicarboxylate transport AsmA_2 PF13502.6 AMK77647.1 - 5.1e-06 26.2 1.5 0.00027 20.5 0.0 2.9 2 0 0 2 2 2 2 AsmA-like C-terminal region Beta_elim_lyase PF01212.21 AMK77648.1 - 6.4e-53 179.9 0.0 7.9e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AMK77648.1 - 0.0046 16.3 0.1 2.2 7.5 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family EcKinase PF02958.20 AMK77649.1 - 1.3e-18 67.3 0.0 3.5e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 AMK77649.1 - 2.2e-09 37.6 1.2 3.3e-09 37.0 1.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 AMK77649.1 - 3.5e-09 36.0 0.0 5.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Inositol_P PF00459.25 AMK77650.1 - 1.8e-40 139.2 0.0 2.2e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 AMK77650.1 - 0.031 13.7 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain KTSC PF13619.6 AMK77651.1 - 3.3e-17 62.0 0.1 3.7e-17 61.9 0.1 1.0 1 0 0 1 1 1 1 KTSC domain adh_short PF00106.25 AMK77652.1 - 3.2e-36 124.6 0.0 4.1e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 AMK77652.1 - 9.4e-28 97.3 0.0 1.1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 AMK77652.1 - 2.4e-11 43.9 0.1 3e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AMK77652.1 - 1.4e-05 25.0 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 AMK77652.1 - 0.0074 15.4 0.1 0.012 14.7 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 AMK77652.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 AMK77652.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pro_CA PF00484.19 AMK77653.1 - 1e-48 165.6 0.1 1.2e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Sulfate_transp PF00916.20 AMK77654.1 - 8.9e-61 205.7 20.1 9.9e-61 205.6 19.5 1.4 1 1 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 AMK77654.1 - 8.9e-06 26.1 0.7 8.9e-06 26.1 0.7 4.4 4 1 0 4 4 4 1 Molybdate transporter of MFS superfamily BBP2 PF07642.11 AMK77655.1 - 1.6e-83 280.7 0.7 1.8e-83 280.6 0.7 1.0 1 0 0 1 1 1 1 Putative beta-barrel porin-2, OmpL-like. bbp2 LysR_substrate PF03466.20 AMK77657.1 - 4.2e-38 130.8 1.3 6.4e-38 130.2 1.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK77657.1 - 5.1e-19 68.0 0.1 1.2e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 AMK77657.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_psq PF05225.16 AMK77657.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Flavodoxin_2 PF02525.17 AMK77658.1 - 1e-47 162.4 0.1 1.1e-47 162.3 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 AMK77658.1 - 7.8e-16 58.2 0.2 9.6e-16 57.9 0.2 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase RNase_Zc3h12a PF11977.8 AMK77658.1 - 0.14 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Pirin PF02678.16 AMK77659.1 - 3.4e-36 123.5 0.1 6.6e-36 122.6 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AMK77659.1 - 5.8e-31 106.9 0.0 1.8e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain DAHP_snth_FXD PF18152.1 AMK77659.1 - 0.02 14.7 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Cupin_2 PF07883.11 AMK77659.1 - 0.029 14.1 0.3 6.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Cupin domain HEPN_SAV2148 PF18725.1 AMK77659.1 - 0.081 12.3 0.0 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 SAV2148-like HEPN Pirin_C_2 PF17954.1 AMK77659.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain LigB PF02900.18 AMK77660.1 - 1.4e-30 106.3 0.0 1.7e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase AAA_32 PF13654.6 AMK77661.1 - 1.7e-195 650.7 0.1 2.1e-195 650.4 0.1 1.0 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 AMK77661.1 - 1.5e-10 41.0 0.1 7.7e-10 38.7 0.1 2.1 2 1 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain MscS_porin PF12795.7 AMK77661.1 - 0.0093 15.5 2.5 0.28 10.7 0.3 2.6 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DC_STAMP PF07782.13 AMK77661.1 - 0.012 15.4 0.3 0.85 9.4 0.3 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Mg_chelatase PF01078.21 AMK77661.1 - 0.013 14.9 0.2 0.31 10.4 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI GIT1_C PF12205.8 AMK77661.1 - 0.08 13.1 0.4 0.29 11.3 0.4 1.9 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term AAA_assoc_2 PF16193.5 AMK77661.1 - 0.19 12.1 1.0 0.64 10.4 1.0 2.0 1 1 0 1 1 1 0 AAA C-terminal domain DUF5082 PF16888.5 AMK77661.1 - 0.23 11.7 5.0 0.45 10.8 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Methyltrans_SAM PF10672.9 AMK77662.1 - 2.2e-14 53.3 0.0 2.8e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 AMK77662.1 - 2.6e-05 23.9 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 AMK77662.1 - 0.0031 18.2 0.0 0.0055 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 AMK77662.1 - 0.0057 16.3 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F UPF0020 PF01170.18 AMK77662.1 - 0.0058 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 AMK77662.1 - 0.0071 17.0 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK77662.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 AMK77662.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 AMK77662.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein AAA_2 PF07724.14 AMK77664.1 - 1.1e-27 97.3 0.0 1.8e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 AMK77664.1 - 9.1e-11 42.3 0.0 2.3e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK77664.1 - 2.3e-09 37.3 0.0 6.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AMK77664.1 - 4e-07 29.9 0.0 6.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 AMK77664.1 - 1.1e-06 29.0 0.0 2.1e-05 24.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 AMK77664.1 - 1.2e-06 28.4 0.0 6.6e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Torsin PF06309.11 AMK77664.1 - 3.7e-06 27.0 0.0 6.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Torsin AAA_30 PF13604.6 AMK77664.1 - 3.2e-05 23.7 0.0 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AMK77664.1 - 3.5e-05 23.7 0.0 8.8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK77664.1 - 0.00017 22.0 1.5 0.00086 19.7 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 AMK77664.1 - 0.00063 19.9 0.0 0.0014 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AMK77664.1 - 0.0008 18.7 0.0 0.0029 16.9 0.0 1.9 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.6 AMK77664.1 - 0.0025 17.8 0.0 0.017 15.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 AMK77664.1 - 0.0026 18.3 0.0 0.0063 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 AMK77664.1 - 0.0027 17.2 0.0 0.049 13.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activ_2 PF14532.6 AMK77664.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 AMK77664.1 - 0.0049 17.2 0.3 0.019 15.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 AMK77664.1 - 0.0056 16.1 0.0 0.058 12.8 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AMK77664.1 - 0.021 14.6 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 AMK77664.1 - 0.021 14.0 0.0 0.099 11.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_11 PF13086.6 AMK77664.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 AMK77664.1 - 0.045 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 AMK77664.1 - 0.063 13.6 0.1 1.5 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 AMK77664.1 - 0.078 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 AMK77664.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 AMK77664.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 AMK77664.1 - 0.23 10.5 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 P5-ATPase PF12409.8 AMK77664.1 - 1.3 9.2 5.2 0.73 9.9 1.6 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter DUF4792 PF16040.5 AMK77666.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) HupE_UreJ_2 PF13795.6 AMK77667.1 - 3.2e-50 169.8 9.5 4.4e-50 169.4 9.5 1.2 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ PF04955.12 AMK77667.1 - 0.0015 18.1 8.6 0.0024 17.4 8.6 1.5 1 1 0 1 1 1 1 HupE / UreJ protein Ferric_reduct PF01794.19 AMK77667.1 - 0.014 15.5 2.8 0.014 15.5 2.8 2.3 1 1 1 2 2 2 0 Ferric reductase like transmembrane component YtpI PF14007.6 AMK77667.1 - 0.021 14.9 0.3 0.021 14.9 0.3 2.7 2 1 1 3 3 3 0 YtpI-like protein DUF2085 PF09858.9 AMK77667.1 - 4.5 7.8 11.0 2.5 8.7 3.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) HemolysinCabind PF00353.19 AMK77668.1 - 2.6e-14 52.9 21.5 2.1e-10 40.3 2.8 4.2 5 0 0 5 5 5 2 RTX calcium-binding nonapeptide repeat (4 copies) DUF11 PF01345.18 AMK77668.1 - 3.7e-10 40.0 6.0 3.7e-10 40.0 6.0 3.3 2 2 0 2 2 2 1 Domain of unknown function DUF11 DUF4139 PF13598.6 AMK77668.1 - 0.036 13.8 0.1 0.083 12.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4139) CARDB PF07705.11 AMK77668.1 - 0.054 13.8 5.7 0.059 13.6 3.0 2.6 2 1 0 2 2 2 0 CARDB Pyrophosphatase PF00719.19 AMK77670.1 - 7.4e-44 149.4 0.0 8.6e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase ADSL_C PF10397.9 AMK77670.1 - 0.091 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus EAL PF00563.20 AMK77672.1 - 1.8e-73 247.0 0.7 4.6e-73 245.6 0.0 2.0 2 0 0 2 2 2 1 EAL domain PAS_4 PF08448.10 AMK77672.1 - 1.8e-59 198.8 0.7 1.4e-21 76.8 0.0 5.6 5 0 0 5 5 5 5 PAS fold GGDEF PF00990.21 AMK77672.1 - 5.6e-55 185.5 0.8 1.7e-54 183.9 0.8 1.9 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK77672.1 - 4.2e-40 136.2 0.1 1.7e-11 44.3 0.0 5.7 5 1 0 5 5 5 4 PAS domain PAS PF00989.25 AMK77672.1 - 1e-36 125.4 1.3 1.7e-09 37.7 0.1 5.6 5 0 0 5 5 5 4 PAS fold PAS_3 PF08447.12 AMK77672.1 - 1.4e-31 108.6 5.2 7.4e-18 64.6 0.2 4.5 4 0 0 4 4 4 3 PAS fold MASE1 PF05231.14 AMK77672.1 - 3.1e-29 102.1 36.5 4.4e-29 101.6 36.5 1.1 1 0 0 1 1 1 1 MASE1 PAS_8 PF13188.7 AMK77672.1 - 1.6e-17 63.1 0.5 0.00012 22.1 0.0 6.1 5 1 1 6 6 6 4 PAS domain PAS_10 PF13596.6 AMK77672.1 - 3.4e-07 30.8 0.1 0.077 13.6 0.0 4.6 5 0 0 5 5 4 2 PAS domain PAS_7 PF12860.7 AMK77672.1 - 1.8e-05 24.9 1.3 2.1 8.6 0.0 5.1 5 1 0 5 5 5 2 PAS fold dCache_1 PF02743.18 AMK77672.1 - 0.0025 17.6 0.1 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 Cache domain PAS_12 PF18095.1 AMK77672.1 - 0.12 12.0 0.1 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Bact_transglu_N PF08379.10 AMK77673.1 - 2.3e-27 95.7 1.9 3.6e-27 95.1 1.1 1.8 2 0 0 2 2 2 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 AMK77673.1 - 1.9e-20 73.4 0.0 3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Vitelline_membr PF10542.9 AMK77673.1 - 0.0085 15.9 0.4 0.016 15.1 0.4 1.4 1 0 0 1 1 1 1 Vitelline membrane cysteine-rich region DUF553 PF04473.12 AMK77673.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain CP_ATPgrasp_2 PF14403.6 AMK77674.1 - 8.8e-155 515.2 0.0 1.3e-154 514.6 0.0 1.3 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AMK77674.1 - 1.4e-115 385.9 0.0 2.3e-115 385.2 0.0 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Alpha-E PF04168.12 AMK77674.1 - 1.2e-69 235.3 6.3 1.9e-69 234.7 6.3 1.3 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. CP_ATPgrasp_2 PF14403.6 AMK77675.1 - 1.2e-161 537.8 0.0 1.4e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 AMK77675.1 - 2.8e-137 457.2 0.2 5.3e-137 456.3 0.0 1.5 2 0 0 2 2 2 1 A circularly permuted ATPgrasp ATPgrasp_YheCD PF14398.6 AMK77675.1 - 0.0034 16.7 0.0 0.14 11.4 0.0 2.6 2 1 0 2 2 2 1 YheC/D like ATP-grasp Alpha-E PF04168.12 AMK77676.1 - 6.6e-78 262.5 4.6 7.5e-78 262.3 4.6 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. PA28_alpha PF02251.18 AMK77678.1 - 0.017 15.1 0.2 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit NAD_synthase PF02540.17 AMK77679.1 - 3.5e-73 245.7 0.0 5.5e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 AMK77679.1 - 8.1e-35 120.4 0.1 1.2e-34 119.9 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase QueC PF06508.13 AMK77679.1 - 0.024 14.1 0.0 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC CoA_binding PF02629.19 AMK77680.1 - 1.1e-28 99.7 1.6 2.1e-28 98.9 0.2 2.2 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 AMK77680.1 - 3.2e-19 69.2 0.9 5.5e-19 68.5 0.9 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 AMK77680.1 - 9.2e-11 41.7 0.4 1.8e-10 40.8 0.1 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 AMK77681.1 - 4.1e-79 264.8 0.1 5.9e-79 264.3 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 AMK77681.1 - 2.5e-22 79.3 2.9 4.6e-22 78.5 2.9 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 AMK77681.1 - 1.2e-09 38.0 0.7 3e-09 36.7 0.7 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 AMK77681.1 - 4.6e-05 23.3 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HATPase_c PF02518.26 AMK77682.1 - 3.2e-17 63.1 0.0 6.6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK77682.1 - 1.8e-15 56.7 1.3 6.2e-15 55.0 1.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AMK77682.1 - 9.6e-05 22.3 0.1 0.00023 21.1 0.1 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 AMK77682.1 - 0.00044 20.2 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF3877 PF12993.7 AMK77682.1 - 0.018 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) PAS_7 PF12860.7 AMK77682.1 - 0.06 13.5 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 PAS fold CHAD PF05235.14 AMK77682.1 - 0.11 12.4 3.7 1.2 9.1 3.7 2.1 1 1 0 1 1 1 0 CHAD domain DUF4880 PF16220.5 AMK77682.1 - 0.8 9.6 4.1 1.2 9.1 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) Sigma54_activat PF00158.26 AMK77683.1 - 2.2e-69 232.5 0.0 3.6e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK77683.1 - 3.9e-29 101.5 0.0 1.3e-28 99.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK77683.1 - 1.5e-25 89.5 0.5 3.2e-25 88.5 0.5 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AMK77683.1 - 1.3e-15 56.9 1.0 1.3e-15 56.9 1.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK77683.1 - 0.00066 19.7 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_30 PF13556.6 AMK77683.1 - 0.0016 18.2 1.9 0.0034 17.1 0.1 2.5 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain AAA PF00004.29 AMK77683.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HTH_50 PF18024.1 AMK77683.1 - 0.04 13.5 0.4 0.092 12.4 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FAP PF07174.11 AMK77684.1 - 0.0071 15.9 13.8 0.0083 15.6 13.8 1.2 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) FAM70 PF14967.6 AMK77684.1 - 0.092 12.2 4.8 0.11 11.9 4.8 1.1 1 0 0 1 1 1 0 FAM70 protein PRCC PF10253.9 AMK77684.1 - 0.12 13.1 8.4 0.15 12.8 8.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MSP1_C PF07462.11 AMK77684.1 - 0.25 10.0 4.8 0.31 9.7 4.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Hamartin PF04388.12 AMK77684.1 - 0.26 9.9 4.2 0.28 9.8 4.2 1.0 1 0 0 1 1 1 0 Hamartin protein ATP19 PF11022.8 AMK77684.1 - 1.8 9.0 5.4 13 6.3 5.4 2.4 1 1 0 1 1 1 0 ATP synthase subunit K ATP-synt_G PF04718.15 AMK77684.1 - 5.1 8.0 6.8 78 4.2 5.0 2.3 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit EAL PF00563.20 AMK77685.1 - 6.5e-72 241.9 0.3 1.8e-71 240.5 0.0 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK77685.1 - 6.8e-32 110.4 0.1 1.4e-31 109.4 0.1 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK77685.1 - 0.0004 20.5 0.0 0.00094 19.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain SMC_N PF02463.19 AMK77685.1 - 0.025 14.0 0.2 0.073 12.5 0.2 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain HDOD PF08668.12 AMK77686.1 - 8.5e-49 165.7 0.0 1.1e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK77686.1 - 0.0015 18.7 0.0 0.0053 17.0 0.0 1.9 2 1 0 2 2 2 1 HD domain Porin_O_P PF07396.11 AMK77687.1 - 3e-62 210.9 18.3 4.1e-62 210.4 18.3 1.1 1 0 0 1 1 1 1 Phosphate-selective porin O and P Seryl_tRNA_N PF02403.22 AMK77687.1 - 1.1 9.6 5.4 1.9 8.8 5.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cation_efflux PF01545.21 AMK77688.1 - 1.2e-37 129.6 12.1 1.5e-37 129.2 12.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AMK77688.1 - 8.7e-20 70.6 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter CMD PF02627.20 AMK77688.1 - 0.021 14.8 0.7 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family NIL PF09383.10 AMK77688.1 - 0.099 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 NIL domain DUF973 PF06157.11 AMK77688.1 - 0.13 11.3 6.1 0.26 10.3 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Ycf66_N PF07444.11 AMK77688.1 - 0.5 10.5 0.0 0.5 10.5 0.0 3.4 3 2 0 3 3 3 0 Ycf66 protein N-terminus GtrA PF04138.14 AMK77688.1 - 3.3 8.0 8.3 7.2 6.9 0.8 3.1 3 0 0 3 3 3 0 GtrA-like protein Prok-JAB PF14464.6 AMK77689.1 - 6.1e-15 55.0 0.0 7.2e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4329 PF14220.6 AMK77689.1 - 0.0042 17.1 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) JAB PF01398.21 AMK77689.1 - 0.0085 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Toxin-JAB1 PF15659.6 AMK77689.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 JAB-like toxin 1 MTS PF05175.14 AMK77690.1 - 4e-19 68.8 0.2 6.1e-17 61.7 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase small domain PrmC_N PF17827.1 AMK77690.1 - 5.2e-18 65.4 0.1 1.4e-17 64.0 0.1 1.8 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 AMK77690.1 - 1.6e-15 57.2 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AMK77690.1 - 1.6e-08 34.3 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AMK77690.1 - 2.8e-08 34.4 0.0 6.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 AMK77690.1 - 7.9e-06 25.7 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 AMK77690.1 - 3.9e-05 24.2 0.0 9.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK77690.1 - 4.4e-05 23.4 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AMK77690.1 - 5.6e-05 23.1 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AMK77690.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 AMK77690.1 - 8.9e-05 23.2 0.1 0.0074 17.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AMK77690.1 - 0.00012 21.8 0.0 0.00031 20.4 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 GidB PF02527.15 AMK77690.1 - 0.00075 18.9 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 AMK77690.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 AMK77690.1 - 0.0078 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 AMK77690.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 AMK77690.1 - 0.0095 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TRM PF02005.16 AMK77690.1 - 0.025 13.7 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase N6_Mtase PF02384.16 AMK77690.1 - 0.042 13.1 0.0 0.082 12.2 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_32 PF13679.6 AMK77690.1 - 0.098 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 AMK77690.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PCRF PF03462.18 AMK77691.1 - 5e-75 251.6 1.4 5e-75 251.6 1.4 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AMK77691.1 - 3.1e-41 140.0 1.5 3.1e-41 140.0 1.5 2.1 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 AMK77691.1 - 0.0013 19.0 0.3 0.0013 19.0 0.3 3.1 3 0 0 3 3 3 1 ABC transporter C-terminal domain DUF4407 PF14362.6 AMK77691.1 - 0.42 9.9 6.5 0.5 9.7 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF349 PF03993.12 AMK77691.1 - 1.3 9.4 10.3 3.4 8.1 1.8 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) KfrA_N PF11740.8 AMK77691.1 - 8.6 7.1 15.3 33 5.2 7.3 3.4 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term GlutR_N PF05201.15 AMK77692.1 - 2.1e-51 173.6 0.0 6.7e-51 171.9 0.0 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 AMK77692.1 - 1.8e-48 164.1 0.1 3.3e-48 163.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 AMK77692.1 - 2.9e-28 98.2 4.0 6.9e-28 96.9 4.0 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 AMK77692.1 - 0.00076 20.0 0.2 0.013 16.1 0.1 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 AMK77692.1 - 0.0044 16.0 0.1 0.0077 15.2 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 AMK77692.1 - 0.01 16.1 0.1 0.037 14.3 0.1 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 AMK77692.1 - 0.09 12.8 2.0 0.2 11.6 0.6 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Type_III_YscX PF09474.10 AMK77692.1 - 0.098 13.0 1.8 0.26 11.6 1.6 1.8 1 1 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) TPR_14 PF13428.6 AMK77693.1 - 1.5e-33 112.6 34.4 6.3e-05 23.5 0.0 12.7 4 3 10 14 14 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 AMK77693.1 - 1.5e-33 112.2 15.7 0.00062 19.7 0.0 11.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 AMK77693.1 - 4.7e-30 104.0 23.1 9.1e-06 26.2 0.0 7.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 AMK77693.1 - 7.7e-29 100.0 35.0 1.4e-09 38.4 0.1 8.8 4 1 6 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 AMK77693.1 - 4.3e-25 85.8 16.1 0.00018 21.4 0.1 9.3 11 0 0 11 11 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 AMK77693.1 - 1e-21 75.7 13.4 0.013 15.3 0.2 10.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 AMK77693.1 - 5e-21 74.8 17.1 8.6e-07 29.2 0.8 8.3 5 2 4 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK77693.1 - 9.6e-21 73.8 0.8 2.9e-06 27.4 0.0 5.2 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AMK77693.1 - 7.1e-17 61.3 25.6 1.4e-06 28.4 0.5 7.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 AMK77693.1 - 1.1e-16 60.3 14.2 0.23 12.2 0.1 10.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 AMK77693.1 - 1.1e-16 59.5 14.3 0.0039 17.1 0.5 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 AMK77693.1 - 4.6e-14 52.3 26.3 7.7e-08 31.9 3.3 6.0 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 AMK77693.1 - 1.4e-13 50.2 6.0 0.0041 17.4 0.0 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 AMK77693.1 - 3.3e-12 45.9 16.4 0.00084 19.0 0.3 8.0 8 0 0 8 8 8 3 TPR repeat TPR_4 PF07721.14 AMK77693.1 - 1.9e-11 43.5 1.3 0.45 11.3 0.0 7.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 AMK77693.1 - 6.6e-10 38.5 16.8 0.015 15.1 0.7 7.9 10 0 0 10 10 7 3 Tetratricopeptide repeat NARP1 PF12569.8 AMK77693.1 - 1.1e-07 31.2 8.2 0.19 10.6 0.0 4.5 2 2 0 4 4 4 3 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 AMK77693.1 - 1.9e-06 27.8 11.4 1.2 9.3 0.1 6.5 5 2 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 AMK77693.1 - 2.6e-06 27.1 13.3 0.29 10.5 0.2 4.4 2 2 1 4 4 4 2 Coatomer epsilon subunit TPR_MalT PF17874.1 AMK77693.1 - 0.00015 21.3 17.3 0.75 9.1 0.1 6.6 5 1 1 7 7 7 2 MalT-like TPR region TPR_20 PF14561.6 AMK77693.1 - 0.00023 21.5 22.0 0.053 13.9 0.2 6.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 AMK77693.1 - 0.00027 20.7 22.4 0.064 13.0 2.1 5.4 2 1 2 5 5 5 3 Tetratricopeptide repeat-like domain PPR PF01535.20 AMK77693.1 - 0.00083 19.4 1.2 44 4.6 0.0 6.5 7 1 1 8 8 5 0 PPR repeat DUF4919 PF16266.5 AMK77693.1 - 0.00084 19.3 0.8 0.13 12.2 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4919) PknG_TPR PF16918.5 AMK77693.1 - 0.0012 17.6 7.1 0.0018 17.1 0.0 3.8 2 1 3 5 5 5 1 Protein kinase G tetratricopeptide repeat SRP_TPR_like PF17004.5 AMK77693.1 - 0.0025 17.8 2.2 2 8.5 0.2 3.4 3 1 1 4 4 3 2 Putative TPR-like repeat RPN7 PF10602.9 AMK77693.1 - 0.0028 17.4 2.6 0.027 14.2 1.6 3.1 2 1 0 2 2 2 1 26S proteasome subunit RPN7 DUF4192 PF13830.6 AMK77693.1 - 0.0029 17.7 10.5 1.2 9.1 0.2 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF4192) zf-DNA_Pol PF08996.10 AMK77693.1 - 0.067 12.9 0.3 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger MIT PF04212.18 AMK77693.1 - 0.2 11.8 8.1 2 8.5 0.1 4.7 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 AMK77693.1 - 3.8 8.0 8.3 2.2e+02 2.3 0.3 4.9 3 1 2 5 5 5 0 Alkyl sulfatase dimerisation LolB PF03550.14 AMK77694.1 - 6.5e-32 110.7 0.0 8.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein LolB GHMP_kinases_N PF00288.26 AMK77695.1 - 1e-11 44.9 0.0 2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AMK77695.1 - 5.3e-06 26.7 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Pribosyltran_N PF13793.6 AMK77696.1 - 4.1e-49 165.4 0.2 3.5e-48 162.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AMK77696.1 - 4.3e-30 105.1 1.7 1.8e-29 103.1 0.5 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AMK77696.1 - 1.2e-19 70.4 1.7 3.6e-19 68.8 0.9 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DJ-1_PfpI PF01965.24 AMK77696.1 - 0.078 12.8 0.2 0.37 10.6 0.2 1.9 2 0 0 2 2 2 0 DJ-1/PfpI family Ribosomal_TL5_C PF14693.6 AMK77697.1 - 5.1e-28 97.3 0.9 8.9e-28 96.5 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AMK77697.1 - 3.9e-24 85.0 0.1 6.3e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L25p family Pept_tRNA_hydro PF01195.19 AMK77698.1 - 1.4e-52 178.1 0.0 1.6e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase GTP_EFTU PF00009.27 AMK77699.1 - 1.2e-58 197.9 0.0 1.6e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AMK77699.1 - 5.6e-34 116.8 0.0 1.1e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AMK77699.1 - 1.9e-16 60.2 6.4 5.2e-16 58.8 6.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AMK77699.1 - 2.8e-05 24.2 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AMK77699.1 - 0.02 14.8 0.1 0.19 11.6 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase CbiA PF01656.23 AMK77699.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SecE PF00584.20 AMK77700.1 - 3.4e-18 65.3 6.0 3.4e-18 65.3 6.0 2.9 2 1 1 3 3 3 1 SecE/Sec61-gamma subunits of protein translocation complex Ceramidase PF05875.12 AMK77700.1 - 0.0011 18.5 4.1 0.0014 18.2 4.1 1.1 1 0 0 1 1 1 1 Ceramidase NusG PF02357.19 AMK77701.1 - 1.6e-27 95.8 0.1 2.7e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 AMK77701.1 - 1.4e-07 31.2 0.1 3e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 KOW motif Ribosomal_L11_N PF03946.14 AMK77702.1 - 5.2e-33 112.7 0.1 9.9e-33 111.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AMK77702.1 - 1e-28 99.6 1.1 1.5e-28 99.1 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L1 PF00687.21 AMK77703.1 - 4.4e-53 180.1 0.0 5.9e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L10 PF00466.20 AMK77704.1 - 2.4e-24 85.4 0.0 4.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L12 PF00542.19 AMK77705.1 - 5.6e-31 106.7 5.0 5.6e-31 106.7 5.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AMK77705.1 - 2e-17 62.6 9.8 2.3e-17 62.4 8.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain RNA_pol_Rpb2_6 PF00562.28 AMK77706.1 - 4.7e-163 542.8 0.6 9.8e-162 538.5 0.7 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 AMK77706.1 - 1.8e-39 135.3 0.0 4.9e-39 134.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 AMK77706.1 - 8.5e-30 102.7 0.0 1.8e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 AMK77706.1 - 1.5e-28 99.7 0.1 3.6e-18 65.9 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 AMK77706.1 - 1.1e-26 93.0 0.1 2.5e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 AMK77706.1 - 4.4e-23 81.3 3.4 1.1e-22 80.0 1.9 2.7 3 0 0 3 3 3 1 RNA polymerase beta subunit external 1 domain DUF433 PF04255.14 AMK77706.1 - 0.051 13.4 0.3 7.3 6.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Ribosomal_S13 PF00416.22 AMK77706.1 - 0.5 10.8 3.3 0.46 10.9 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S13/S18 RNA_pol_Rpb1_1 PF04997.12 AMK77707.1 - 3.6e-86 289.3 0.0 5.4e-86 288.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AMK77707.1 - 1.1e-78 264.4 0.2 1.9e-78 263.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AMK77707.1 - 2.2e-37 128.8 0.0 1.2e-26 93.9 0.0 2.6 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AMK77707.1 - 1.8e-27 96.2 0.0 3.8e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AMK77707.1 - 2.8e-18 65.8 0.2 2.8e-18 65.8 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.22 AMK77707.1 - 2.8e-05 24.3 0.1 0.00077 19.6 0.0 3.1 3 0 0 3 3 3 1 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 AMK77707.1 - 9.7e-05 22.1 1.1 0.13 12.1 0.1 3.7 4 0 0 4 4 4 2 Biotin-lipoyl like ApbA_C PF08546.11 AMK77707.1 - 0.00057 20.1 0.1 0.0016 18.7 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Apocytochr_F_C PF01333.19 AMK77707.1 - 0.0009 19.3 0.9 0.17 12.0 0.0 3.6 3 0 0 3 3 3 1 Apocytochrome F, C-terminal Ribosom_S12_S23 PF00164.25 AMK77708.1 - 2.4e-42 143.1 1.1 2.9e-42 142.9 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 AMK77709.1 - 8.8e-65 216.9 4.2 9.8e-65 216.8 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GTP_EFTU PF00009.27 AMK77710.1 - 3.4e-66 222.5 0.0 5e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AMK77710.1 - 1.8e-49 166.6 0.1 9.4e-49 164.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 AMK77710.1 - 1.1e-32 111.9 0.0 2.6e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AMK77710.1 - 7.7e-30 102.8 0.0 2.2e-29 101.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AMK77710.1 - 2.3e-17 63.2 0.8 6.1e-17 61.8 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AMK77710.1 - 9.5e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU PF00009.27 AMK77711.1 - 1.2e-58 197.9 0.0 1.6e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AMK77711.1 - 5.6e-34 116.8 0.0 1.1e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AMK77711.1 - 1.9e-16 60.2 6.4 5.2e-16 58.8 6.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AMK77711.1 - 2.8e-05 24.2 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AMK77711.1 - 0.02 14.8 0.1 0.19 11.6 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase CbiA PF01656.23 AMK77711.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_S10 PF00338.22 AMK77712.1 - 8.8e-35 118.9 0.0 9.9e-35 118.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L3 PF00297.22 AMK77713.1 - 6.6e-13 48.4 5.7 1.1e-12 47.7 2.9 2.4 1 1 2 3 3 3 2 Ribosomal protein L3 Ribosomal_L4 PF00573.22 AMK77714.1 - 1.2e-56 191.5 0.2 1.3e-56 191.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Dak1_2 PF13684.6 AMK77714.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Ribosomal_L23 PF00276.20 AMK77715.1 - 4.6e-32 110.2 1.0 5.4e-32 110.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 ubiquitin PF00240.23 AMK77715.1 - 0.022 14.5 0.1 0.058 13.2 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin family DUF1115 PF06544.12 AMK77715.1 - 0.03 14.4 0.3 0.039 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Ribosomal_L2_C PF03947.18 AMK77716.1 - 5.4e-58 194.7 3.2 8.8e-58 194.0 3.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AMK77716.1 - 1e-32 111.9 0.6 9.1e-32 108.9 0.6 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain RsgI_N PF12791.7 AMK77716.1 - 0.01 15.7 0.1 0.28 11.1 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Ribosomal_L22 PF00237.19 AMK77717.1 - 3e-32 110.9 1.4 3.3e-32 110.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 AMK77718.1 - 6.2e-41 138.8 2.1 6.2e-41 138.8 2.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AMK77718.1 - 4.9e-20 71.1 0.9 4.9e-20 71.1 0.9 1.7 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 AMK77718.1 - 4.8e-05 23.2 0.1 9.8e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 KH domain Ribosomal_L16 PF00252.18 AMK77719.1 - 1.5e-49 167.4 0.6 1.6e-49 167.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L29 PF00831.23 AMK77720.1 - 6.6e-26 90.1 3.2 7.8e-26 89.8 3.2 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 AMK77720.1 - 0.0099 16.0 0.7 0.013 15.6 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF1661 PF07877.11 AMK77720.1 - 0.29 10.9 1.5 9.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Ribosomal_S17 PF00366.20 AMK77721.1 - 3.8e-33 113.4 0.9 4.5e-33 113.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF851 PF05867.11 AMK77721.1 - 0.0019 17.7 0.1 0.0019 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF851) DUF4107 PF13389.6 AMK77721.1 - 0.062 13.5 0.1 0.064 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) Ribosomal_L14 PF00238.19 AMK77722.1 - 4.9e-54 181.6 0.8 5.4e-54 181.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ribosomal_L24 PF17136.4 AMK77723.1 - 1.1e-23 83.4 0.3 1.1e-23 83.4 0.3 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AMK77723.1 - 2.2e-06 27.4 2.6 4.8e-06 26.3 2.6 1.7 1 0 0 1 1 1 1 KOW motif MazE_antitoxin PF04014.18 AMK77723.1 - 0.015 15.2 1.9 0.23 11.4 0.6 2.4 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Ribosomal_L5_C PF00673.21 AMK77724.1 - 2.7e-41 139.6 0.0 5.4e-41 138.7 0.0 1.5 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AMK77724.1 - 4.3e-26 91.0 1.4 7.1e-26 90.3 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S8 PF00410.19 AMK77725.1 - 1.5e-48 164.0 0.2 1.6e-48 163.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 AMK77726.1 - 1.5e-32 112.1 1.4 5.2e-19 68.7 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L18p PF00861.22 AMK77727.1 - 6.2e-39 133.0 4.4 6.8e-39 132.8 4.4 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S5_C PF03719.15 AMK77728.1 - 2e-28 97.6 1.6 3.3e-28 96.9 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AMK77728.1 - 7.8e-26 89.8 4.0 7.8e-26 89.8 4.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_L30 PF00327.20 AMK77729.1 - 3.1e-13 49.4 0.2 3.5e-13 49.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 AMK77730.1 - 1.4e-28 100.1 3.1 1.8e-28 99.7 3.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SecY PF00344.20 AMK77731.1 - 3.3e-114 381.2 23.2 4.1e-114 380.9 23.2 1.1 1 0 0 1 1 1 1 SecY translocase ResB PF05140.14 AMK77731.1 - 0.24 10.1 1.3 1.1 7.9 0.3 2.0 2 0 0 2 2 2 0 ResB-like family SieB PF14163.6 AMK77731.1 - 2.5 7.6 5.8 0.59 9.6 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B TM140 PF14985.6 AMK77731.1 - 4.5 6.8 7.4 0.55 9.8 0.4 2.9 3 1 1 4 4 4 0 TM140 protein family Ribosomal_S13 PF00416.22 AMK77732.1 - 4.4e-33 114.4 8.8 3.9e-31 108.1 8.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AMK77732.1 - 0.0005 19.0 0.0 0.00057 18.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HTH_Tnp_Tc3_2 PF01498.18 AMK77732.1 - 0.0063 16.7 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Transposase HHH_5 PF14520.6 AMK77732.1 - 0.009 16.6 0.0 0.026 15.1 0.0 1.8 1 1 1 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 AMK77732.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.8 1 1 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_6 PF14579.6 AMK77732.1 - 0.053 13.8 0.1 0.16 12.2 0.1 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix motif Ribosomal_S11 PF00411.19 AMK77733.1 - 7.5e-50 167.9 0.4 8.8e-50 167.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S4 PF00163.19 AMK77734.1 - 9.1e-29 100.2 3.4 1.5e-28 99.5 3.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AMK77734.1 - 1.8e-17 62.8 0.1 3.5e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AMK77734.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 S4 domain Gemini_AL3 PF01407.17 AMK77734.1 - 0.063 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Geminivirus AL3 protein RNA_pol_L PF01193.24 AMK77735.1 - 2.6e-23 81.2 0.1 1.1e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 AMK77735.1 - 6.1e-23 81.3 0.2 1.3e-22 80.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_A_CTD PF03118.15 AMK77735.1 - 1.3e-22 79.3 0.1 2.6e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain Ribosomal_L17 PF01196.19 AMK77736.1 - 3e-33 114.6 0.0 3.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 UDG PF03167.19 AMK77737.1 - 1.2e-08 35.1 0.0 1.8e-08 34.6 0.0 1.2 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Gp_dh_C PF02800.20 AMK77738.1 - 1.2e-32 112.7 0.0 1.7e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AMK77738.1 - 8.9e-14 51.7 0.0 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Smr PF01713.21 AMK77739.1 - 4.8e-24 84.5 0.0 7.1e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Smr domain SurE PF01975.17 AMK77740.1 - 1.6e-59 201.0 0.0 1.9e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Survival protein SurE PCMT PF01135.19 AMK77741.1 - 9e-59 198.7 0.0 1.1e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 AMK77741.1 - 4.6e-05 22.6 0.0 6.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 AMK77741.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK77741.1 - 0.0048 17.6 0.0 0.0093 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AMK77741.1 - 0.0099 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 AMK77741.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M10 PF00413.24 AMK77742.1 - 8.7e-06 25.7 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin PEP-CTERM PF07589.11 AMK77742.1 - 0.024 14.7 0.1 0.024 14.7 0.1 2.6 3 0 0 3 3 3 0 PEP-CTERM motif Peptidase_M57 PF12388.8 AMK77742.1 - 0.041 13.5 0.6 0.13 11.9 0.1 1.8 2 1 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF3731 PF12531.8 AMK77743.1 - 7.1e-107 356.8 6.6 7.1e-107 356.8 6.6 1.6 2 0 0 2 2 2 1 DNA-K related protein HSP70 PF00012.20 AMK77743.1 - 2.6e-18 65.6 0.0 1.9e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AMK77743.1 - 3e-05 23.0 0.1 0.00068 18.5 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein Radical_SAM PF04055.21 AMK77744.1 - 2.1e-14 54.3 0.0 4.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 AMK77744.1 - 1.3e-09 38.4 0.5 3.4e-09 37.1 0.4 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 AMK77744.1 - 8.2e-06 26.0 0.0 3.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK77744.1 - 0.00022 21.5 0.1 0.001 19.4 0.0 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain GDP_Man_Dehyd PF16363.5 AMK77745.1 - 6.9e-64 216.3 0.0 3e-61 207.7 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AMK77745.1 - 5e-61 206.2 0.0 5.8e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AMK77745.1 - 6.2e-29 100.9 0.0 8.5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AMK77745.1 - 1.3e-15 57.3 0.0 8.4e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AMK77745.1 - 9.5e-15 54.4 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AMK77745.1 - 1.6e-12 47.7 0.0 4.5e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 AMK77745.1 - 2.3e-12 46.7 0.0 8.1e-08 31.7 0.0 2.8 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 AMK77745.1 - 9.8e-10 38.4 0.0 2.3e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 AMK77745.1 - 1.2e-06 28.1 0.0 3.8e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 AMK77745.1 - 0.00067 19.6 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 AMK77745.1 - 0.038 14.2 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 AMK77745.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SIS_2 PF13580.6 AMK77746.1 - 6.3e-16 58.7 0.6 9.7e-16 58.0 0.6 1.3 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 AMK77746.1 - 6.5e-07 29.3 0.2 5.7e-05 23.0 0.2 2.2 1 1 0 1 1 1 1 SIS domain PfkB PF00294.24 AMK77747.1 - 1.8e-20 73.5 1.5 2.6e-20 72.9 0.3 1.8 2 1 0 2 2 2 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 AMK77747.1 - 1.2e-11 44.9 0.0 2.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HU-CCDC81_bac_1 PF18174.1 AMK77747.1 - 0.0024 17.7 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 1 E1_dh PF00676.20 AMK77748.1 - 1.6e-53 181.7 0.0 2e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 AMK77748.1 - 1.2e-06 28.3 2.4 6.5e-05 22.8 1.3 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 AMK77748.1 - 2.6e-05 23.4 0.0 3.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 AMK77748.1 - 0.0034 16.6 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AMK77749.1 - 5.1e-36 124.0 0.0 8.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AMK77749.1 - 4e-16 59.0 0.0 9.7e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain YAcAr PF10686.9 AMK77749.1 - 0.079 12.9 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Radical_SAM PF04055.21 AMK77750.1 - 1.4e-13 51.5 0.1 3.5e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 AMK77750.1 - 0.00031 21.2 0.3 0.0012 19.4 0.1 2.1 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 AMK77750.1 - 0.07 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Glyco_trans_1_2 PF13524.6 AMK77751.1 - 4.2e-19 68.7 0.2 1.2e-12 48.0 0.0 3.3 3 0 0 3 3 3 2 Glycosyl transferases group 1 TPR_2 PF07719.17 AMK77751.1 - 0.13 12.4 0.5 0.59 10.4 0.5 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_trans_1_2 PF13524.6 AMK77752.1 - 1e-06 29.0 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 B12-binding PF02310.19 AMK77753.1 - 9.8e-17 61.1 0.0 2.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Radical_SAM PF04055.21 AMK77753.1 - 6.1e-14 52.7 0.0 1.5e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Methyltransf_14 PF08484.11 AMK77753.1 - 0.0005 19.9 0.0 0.0027 17.5 0.0 2.1 2 1 0 2 2 2 1 C-methyltransferase C-terminal domain Fer4_12 PF13353.6 AMK77753.1 - 0.27 11.5 1.4 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 AMK77753.1 - 1.4 9.1 4.5 0.59 10.3 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain DegT_DnrJ_EryC1 PF01041.17 AMK77754.1 - 3.9e-101 338.9 0.0 4.5e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AMK77754.1 - 3.5e-08 32.8 0.7 4.8e-08 32.3 0.7 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AMK77754.1 - 9.3e-08 31.7 0.3 1.7e-07 30.8 0.3 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AMK77754.1 - 1.2e-06 27.4 0.2 1.7e-06 26.8 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AMK77754.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Epimerase PF01370.21 AMK77755.1 - 2.8e-32 112.1 0.0 3.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK77755.1 - 2.5e-23 83.0 0.0 3.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AMK77755.1 - 5.6e-14 51.9 0.0 8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AMK77755.1 - 6.1e-13 48.4 0.0 8.4e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AMK77755.1 - 2.3e-07 30.2 0.9 1.7e-05 24.1 0.0 2.9 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 AMK77755.1 - 1.3e-06 27.7 0.2 4.3e-06 26.1 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 AMK77755.1 - 0.0045 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Q_salvage PF10343.9 AMK77755.1 - 0.034 13.7 0.3 1.1 8.7 0.1 2.0 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family Pyr_redox PF00070.27 AMK77755.1 - 0.12 13.0 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 AMK77755.1 - 0.12 11.8 0.1 0.66 9.4 0.1 2.2 3 1 0 3 3 3 0 short chain dehydrogenase SPASM PF13186.6 AMK77756.1 - 8.7e-11 42.2 1.3 2.7e-10 40.6 1.3 1.9 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Radical_SAM PF04055.21 AMK77756.1 - 2.3e-09 37.8 0.1 5e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Carbam_trans_N PF02543.15 AMK77757.1 - 1.2e-49 169.9 0.0 1.9e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Carbam_trans_C PF16861.5 AMK77757.1 - 1.4e-49 168.0 0.0 2.3e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Peptidase_M22 PF00814.25 AMK77757.1 - 8.2e-06 25.7 0.1 0.00012 21.9 0.0 2.4 3 0 0 3 3 3 1 Glycoprotease family Methyltransf_31 PF13847.6 AMK77758.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77758.1 - 4.3e-06 27.3 0.1 4e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK77758.1 - 7.9e-06 26.5 0.0 6.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK77758.1 - 0.00038 20.3 0.0 0.00068 19.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77758.1 - 0.0011 19.7 0.2 0.0058 17.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DASH_Hsk3 PF08227.11 AMK77758.1 - 0.023 15.1 0.5 3.6 8.0 0.0 3.7 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like FmrO PF07091.11 AMK77758.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Glyco_trans_1_2 PF13524.6 AMK77759.1 - 1e-12 48.3 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 CTP_transf_3 PF02348.19 AMK77760.1 - 1.4e-20 74.2 0.0 2.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AMK77760.1 - 0.0089 16.4 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain E1_4HB PF16191.5 AMK77760.1 - 0.089 13.0 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle GDP_Man_Dehyd PF16363.5 AMK77761.1 - 1.2e-73 248.4 0.0 1.4e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AMK77761.1 - 1.6e-58 198.1 0.0 1.9e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AMK77761.1 - 6.6e-29 100.8 0.0 8.3e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AMK77761.1 - 1.6e-18 66.9 0.0 1.2e-17 64.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AMK77761.1 - 2.2e-15 56.5 0.0 3.1e-14 52.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 AMK77761.1 - 5.7e-14 51.9 0.0 7.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AMK77761.1 - 2.8e-12 46.9 0.0 3.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AMK77761.1 - 5.8e-08 32.6 0.0 1e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AMK77761.1 - 2.3e-07 30.5 0.0 3.4e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase DegT_DnrJ_EryC1 PF01041.17 AMK77762.1 - 1.4e-84 284.5 0.0 1.9e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 AMK77762.1 - 1.3e-05 24.6 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 AMK77762.1 - 0.00094 17.8 0.1 0.0015 17.1 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 AMK77762.1 - 0.0015 17.4 0.0 0.0022 16.8 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 AMK77762.1 - 0.0016 17.7 0.7 0.0046 16.3 0.6 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Epimerase_2 PF02350.19 AMK77763.1 - 2.6e-91 306.1 0.1 3e-91 305.9 0.1 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_trans_4_4 PF13579.6 AMK77763.1 - 0.00089 19.7 0.6 0.027 14.9 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain T4_deiodinase PF00837.17 AMK77763.1 - 0.047 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase DHHA1 PF02272.19 AMK77763.1 - 0.068 13.6 0.0 0.52 10.7 0.0 2.3 3 0 0 3 3 3 0 DHHA1 domain NeuB PF03102.14 AMK77764.1 - 6.1e-99 330.4 0.0 7.2e-99 330.1 0.0 1.0 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 AMK77764.1 - 1.2e-05 25.9 0.0 6.9e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 SAF domain DUF3301 PF11743.8 AMK77764.1 - 0.024 14.3 0.0 0.35 10.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3301) Hexapep PF00132.24 AMK77765.1 - 3.3e-19 67.8 16.2 1.7e-09 37.0 2.8 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) PglD_N PF17836.1 AMK77765.1 - 3e-07 31.0 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PglD N-terminal domain Hexapep_2 PF14602.6 AMK77765.1 - 5.8e-07 29.1 20.7 4.1e-05 23.2 5.6 4.2 2 1 3 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 AMK77765.1 - 0.048 12.6 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase NTP_transferase PF00483.23 AMK77766.1 - 3.9e-38 131.4 0.0 6.4e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase CBS PF00571.28 AMK77766.1 - 3.3e-14 53.1 0.8 5.1e-07 30.0 0.2 2.8 2 0 0 2 2 2 2 CBS domain NTP_transf_3 PF12804.7 AMK77766.1 - 5.6e-09 36.6 0.0 1.2e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain IspD PF01128.19 AMK77766.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Flagellin_N PF00669.20 AMK77767.1 - 5.5e-40 136.7 13.3 5.5e-40 136.7 13.3 3.0 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AMK77767.1 - 3.7e-26 91.3 8.1 3.7e-26 91.3 8.1 3.2 5 1 1 6 6 6 1 Bacterial flagellin C-terminal helical region CLZ PF16526.5 AMK77767.1 - 0.17 12.3 1.3 2 8.8 0.0 3.2 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels THOC7 PF05615.13 AMK77767.1 - 0.17 12.1 3.1 3.9 7.8 0.3 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 FliS_cochap PF16522.5 AMK77767.1 - 0.21 11.5 6.9 0.81 9.6 0.9 2.6 2 1 0 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 WXG100 PF06013.12 AMK77767.1 - 0.5 10.6 8.1 2 8.7 0.1 3.0 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 AMK77767.1 - 1.7 8.7 5.5 2.8 8.0 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaG PF03646.15 AMK77768.1 - 1.5e-24 86.1 4.2 1.5e-24 86.1 4.2 1.5 2 0 0 2 2 2 1 FlaG protein FeoB_Cyto PF17910.1 AMK77768.1 - 0.14 12.8 0.5 0.28 11.7 0.5 1.7 1 1 0 1 1 1 0 FeoB cytosolic helical domain MDFI PF15316.6 AMK77768.1 - 1.3 9.1 4.0 1.5 8.9 4.0 1.1 1 0 0 1 1 1 0 MyoD family inhibitor FliD_C PF07195.12 AMK77769.1 - 3.8e-48 164.0 10.6 3.8e-48 164.0 10.6 2.7 3 1 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 AMK77769.1 - 2.7e-21 76.0 1.9 2.7e-21 76.0 1.9 5.7 2 1 2 5 5 5 1 Flagellar hook-associated protein 2 N-terminus Flagellin_IN PF07196.13 AMK77769.1 - 4.8e-05 23.5 12.7 4.8e-05 23.5 12.7 3.0 3 1 0 3 3 3 1 Flagellin hook IN motif Prefoldin_2 PF01920.20 AMK77769.1 - 0.042 13.8 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 Prefoldin subunit DUF2968 PF11180.8 AMK77769.1 - 0.079 12.6 0.4 0.3 10.7 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Sipho_Gp157 PF05565.11 AMK77769.1 - 0.11 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 FliS PF02561.14 AMK77770.1 - 3.9e-34 117.4 0.1 4.3e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 Flagellar protein FliS DUF2274 PF10038.9 AMK77770.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) FliT PF05400.13 AMK77771.1 - 5.9e-05 23.8 0.3 8.3e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 Flagellar protein FliT Flagellin_N PF00669.20 AMK77772.1 - 8.1e-40 136.1 13.8 8.1e-40 136.1 13.8 3.0 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 AMK77772.1 - 2.8e-25 88.5 8.0 2.8e-25 88.5 8.0 2.6 3 1 0 3 3 3 1 Bacterial flagellin C-terminal helical region WXG100 PF06013.12 AMK77772.1 - 0.028 14.7 7.3 2 8.7 0.5 3.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG FliS_cochap PF16522.5 AMK77772.1 - 0.046 13.6 2.3 0.43 10.5 0.5 2.7 1 1 1 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 SOR_SNZ PF01680.17 AMK77772.1 - 0.063 13.0 3.0 0.058 13.2 1.1 1.8 2 0 0 2 2 2 0 SOR/SNZ family HTH_46 PF15977.5 AMK77772.1 - 0.082 12.9 0.3 0.3 11.1 0.3 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding THOC7 PF05615.13 AMK77772.1 - 0.8 10.0 3.7 6.6 7.0 0.3 2.7 2 1 0 2 2 2 0 Tho complex subunit 7 MAF_flag10 PF01973.18 AMK77773.1 - 4.9e-38 130.5 0.0 9.2e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF115 TPR_19 PF14559.6 AMK77773.1 - 0.0047 17.4 0.2 0.02 15.4 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat CTP-dep_RFKase PF01982.16 AMK77773.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF120 Cytochrom_C_asm PF01578.20 AMK77774.1 - 7e-31 107.7 22.9 7e-31 107.7 22.9 1.4 1 1 0 1 1 1 1 Cytochrome C assembly protein SRP54 PF00448.22 AMK77775.1 - 8.6e-74 247.4 0.8 1.5e-73 246.6 0.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 AMK77775.1 - 1.1e-29 103.0 7.9 8.1e-29 100.2 2.3 3.4 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 AMK77775.1 - 4.3e-20 71.7 0.3 4.3e-20 71.7 0.3 3.5 3 1 1 4 4 2 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 AMK77775.1 - 7.1e-08 32.8 0.1 2.7e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 AMK77775.1 - 3.7e-06 27.0 0.0 1.4e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 AMK77775.1 - 1.1e-05 24.8 0.0 2.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 AMK77775.1 - 0.00091 18.3 0.1 0.0029 16.6 0.1 1.8 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AMK77775.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AMK77775.1 - 0.0017 18.1 1.2 0.0041 16.8 0.5 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 AMK77775.1 - 0.005 16.4 2.7 0.096 12.3 2.7 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 AMK77775.1 - 0.013 14.8 0.7 0.033 13.5 0.1 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ParA PF10609.9 AMK77775.1 - 0.014 14.9 0.1 0.014 14.9 0.1 2.4 3 0 0 3 3 3 0 NUBPL iron-transfer P-loop NTPase APS_kinase PF01583.20 AMK77775.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.6 AMK77775.1 - 0.016 15.6 0.2 0.033 14.5 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AMK77775.1 - 0.016 14.5 0.1 0.036 13.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 AMK77775.1 - 0.017 14.8 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 AMK77775.1 - 0.017 15.0 1.3 0.17 11.8 0.7 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 AMK77775.1 - 0.019 15.3 0.1 0.052 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AMK77775.1 - 0.026 14.6 0.8 0.16 12.0 0.3 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF1319 PF07028.11 AMK77775.1 - 0.029 14.6 0.1 0.12 12.6 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) ATP_bind_1 PF03029.17 AMK77775.1 - 0.03 14.1 0.6 0.15 11.8 0.1 2.4 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 AMK77775.1 - 0.044 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PFOR_II PF17147.4 AMK77775.1 - 0.046 14.0 0.5 2.6 8.4 0.0 3.2 3 0 0 3 3 3 0 Pyruvate:ferredoxin oxidoreductase core domain II AAA_14 PF13173.6 AMK77775.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 AMK77775.1 - 0.052 13.0 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 AMK77775.1 - 0.064 13.7 1.2 0.41 11.1 0.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AMK77775.1 - 0.08 13.5 0.4 0.49 10.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter ResIII PF04851.15 AMK77775.1 - 0.18 11.8 1.5 0.72 9.8 0.4 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 AMK77775.1 - 0.19 11.7 0.2 0.81 9.7 0.2 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 AMK77775.1 - 0.2 11.1 5.3 3.7 6.9 0.1 3.0 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 AMK77775.1 - 0.36 10.7 5.0 0.15 12.0 0.3 2.6 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 AMK77775.1 - 1.3 9.5 4.5 33 4.9 4.5 2.5 1 1 0 1 1 1 0 AAA domain FliE PF02049.18 AMK77775.1 - 1.8 8.8 6.6 27 5.0 0.6 3.4 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE AAA_25 PF13481.6 AMK77775.1 - 4.5 6.8 7.8 9.5 5.7 4.8 2.7 2 1 0 2 2 2 0 AAA domain Ribosomal_S16 PF00886.19 AMK77776.1 - 2.8e-25 88.1 0.1 3.3e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RimM PF01782.18 AMK77777.1 - 5.4e-24 84.2 0.1 7.5e-24 83.8 0.1 1.2 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AMK77777.1 - 1.6e-07 31.3 0.3 4.2e-07 29.9 0.3 1.7 1 0 0 1 1 1 1 PRC-barrel domain tRNA_m1G_MT PF01746.21 AMK77778.1 - 2e-63 213.7 0.0 2.3e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L19 PF01245.20 AMK77779.1 - 1.2e-50 170.1 2.2 1.3e-50 169.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 DNA_binding_1 PF01035.20 AMK77780.1 - 2.4e-21 75.6 0.0 4.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Phage_integrase PF00589.22 AMK77781.1 - 1.4e-52 177.9 0.1 2.2e-52 177.3 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AMK77781.1 - 3.1e-19 69.0 0.9 2.7e-18 66.0 0.1 2.4 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AMK77781.1 - 1.5e-06 28.6 0.4 2.1e-05 24.9 0.0 2.8 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AMK77781.1 - 0.012 15.9 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF3435 PF11917.8 AMK77781.1 - 0.025 13.5 0.1 0.043 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Integrase_1 PF12835.7 AMK77781.1 - 0.029 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Integrase HTH_52 PF18576.1 AMK77781.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Hexapep PF00132.24 AMK77782.1 - 5.4e-25 86.1 21.4 6.8e-08 31.9 1.6 5.5 4 1 2 6 6 6 5 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 AMK77782.1 - 2.7e-12 47.0 0.0 5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 AMK77782.1 - 0.016 15.0 0.5 0.016 15.0 0.5 5.5 4 2 2 7 7 7 0 Hexapeptide repeat of succinyl-transferase Response_reg PF00072.24 AMK77783.1 - 0.001 19.2 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain TonB_dep_Rec PF00593.24 AMK77784.1 - 3.7e-38 132.6 32.0 5.2e-37 128.8 32.1 2.0 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK77784.1 - 5.7e-21 75.1 0.5 5.7e-21 75.1 0.5 2.1 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK77784.1 - 2.5e-12 46.5 1.8 6.1e-12 45.2 1.3 1.9 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family EAL PF00563.20 AMK77785.1 - 8.7e-60 202.2 0.4 4.7e-59 199.8 0.0 2.2 3 0 0 3 3 3 1 EAL domain GGDEF PF00990.21 AMK77785.1 - 3.9e-41 140.5 0.2 1.9e-40 138.2 0.1 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain CHASE8 PF17152.4 AMK77785.1 - 3.6e-16 59.3 0.0 7.3e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Periplasmic sensor domain PAS_3 PF08447.12 AMK77785.1 - 1.5e-12 47.6 0.0 4.2e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold HAMP PF00672.25 AMK77785.1 - 1.3e-10 41.4 0.3 6.8e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 HAMP domain PAS_11 PF14598.6 AMK77785.1 - 3.2e-10 40.1 0.0 7.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AMK77785.1 - 5.8e-10 39.4 0.5 2.3e-09 37.5 0.1 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK77785.1 - 2.1e-09 37.4 0.2 5.3e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AMK77785.1 - 1.2e-05 25.5 0.0 3.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK77785.1 - 0.0054 16.7 0.4 0.032 14.3 0.1 2.5 2 0 0 2 2 2 1 PAS domain EI24 PF07264.11 AMK77785.1 - 0.013 15.7 0.1 0.035 14.3 0.1 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF948 PF06103.11 AMK77785.1 - 2.8 8.3 6.4 0.27 11.5 0.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4154 PF13689.6 AMK77786.1 - 5e-37 127.3 0.0 6.4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like Peptidase_M18 PF02127.15 AMK77787.1 - 1.8e-128 429.0 0.0 2.1e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 AMK77787.1 - 0.00045 19.3 0.0 0.11 11.5 0.0 2.1 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase SelR PF01641.18 AMK77788.1 - 2.6e-56 188.9 0.2 3e-56 188.7 0.2 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 AMK77788.1 - 0.013 15.6 1.3 0.041 14.1 1.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 AMK77788.1 - 0.014 14.3 2.1 0.17 10.8 0.1 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-C2HC5 PF06221.13 AMK77788.1 - 0.089 12.8 4.0 1 9.4 0.8 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Zn_ribbon_2 PF12674.7 AMK77788.1 - 1.6 9.5 5.8 19 6.0 0.2 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-Mss51 PF13824.6 AMK77788.1 - 5.3 7.2 9.7 40 4.4 5.0 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Pyr_redox_2 PF07992.14 AMK77789.1 - 6.2e-19 68.3 0.0 2.7e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK77789.1 - 0.0016 19.0 0.7 0.5 10.9 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK77789.1 - 0.0038 16.9 0.2 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DUF2892 PF11127.8 AMK77790.1 - 2.2e-14 53.2 1.1 2.4e-14 53.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) Ion_trans PF00520.31 AMK77792.1 - 1.9e-32 112.4 13.4 2.4e-32 112.1 13.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AMK77792.1 - 4.4e-14 52.2 8.0 4.4e-14 52.2 8.0 2.2 2 1 1 3 3 3 1 Ion channel zf-ribbon_3 PF13248.6 AMK77792.1 - 1.2e-05 24.5 2.0 1.9e-05 23.9 2.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AMK77792.1 - 0.011 15.7 0.9 0.018 15.1 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 AMK77792.1 - 0.04 13.6 3.5 0.06 13.1 3.0 1.6 1 1 1 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 AMK77792.1 - 0.1 12.3 1.2 13 5.6 0.2 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.13 AMK77792.1 - 0.59 9.9 2.7 1.7 8.4 2.7 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Oxidored_nitro PF00148.19 AMK77793.1 - 6e-108 361.1 0.0 6.9e-108 360.9 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NDUFB11 PF17250.2 AMK77793.1 - 0.05 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Hydrolase PF00702.26 AMK77793.1 - 0.099 12.9 0.0 0.29 11.4 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Oxidored_nitro PF00148.19 AMK77794.1 - 1.9e-109 366.1 0.0 2.1e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Nitro_FeMo-Co PF02579.17 AMK77795.1 - 5.5e-20 71.5 0.2 8.5e-20 70.9 0.2 1.3 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor DUF269 PF03270.13 AMK77796.1 - 1.8e-48 163.6 0.0 2.4e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF269 OST-HTH PF12872.7 AMK77796.1 - 0.045 13.6 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Rop-like PF05082.13 AMK77797.1 - 5.2e-24 83.8 2.9 5.8e-24 83.7 2.9 1.0 1 0 0 1 1 1 1 Rop-like Fer4 PF00037.27 AMK77798.1 - 4.5e-12 45.3 15.9 7.1e-07 28.8 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AMK77798.1 - 7e-12 45.3 21.2 1.3e-08 34.9 12.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK77798.1 - 4.1e-11 42.8 11.3 4.7e-10 39.5 11.3 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK77798.1 - 5.4e-11 42.9 24.6 2.6e-09 37.5 11.3 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK77798.1 - 5.3e-10 40.1 4.0 5.3e-10 40.1 4.0 1.4 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AMK77798.1 - 1.1e-09 38.3 25.2 1.1e-08 35.0 10.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK77798.1 - 5.3e-09 36.5 5.5 1e-08 35.5 5.5 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK77798.1 - 8.6e-09 35.7 7.3 1.2e-08 35.3 7.3 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK77798.1 - 9.6e-09 34.9 16.0 2e-05 24.4 3.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AMK77798.1 - 3.7e-08 33.0 13.3 0.00026 20.9 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AMK77798.1 - 1e-06 29.3 20.0 0.0013 19.6 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 AMK77798.1 - 1.3e-06 29.2 9.8 0.00031 21.5 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AMK77798.1 - 4.6e-06 26.8 6.3 0.0035 17.5 1.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AMK77798.1 - 1.1e-05 25.9 16.1 0.00027 21.4 2.5 2.4 1 1 2 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 AMK77798.1 - 4.8e-05 23.5 12.9 0.0021 18.4 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 AMK77798.1 - 0.018 15.7 17.1 0.024 15.4 4.5 2.2 1 1 1 2 2 2 0 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.10 AMK77798.1 - 0.13 12.6 5.4 1.3 9.3 2.7 2.1 2 0 0 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 AMK77798.1 - 0.79 9.9 8.5 3.2 7.9 3.4 2.8 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S AFP PF02420.15 AMK77798.1 - 6.1 7.5 11.0 3.1 8.4 1.0 3.4 2 1 0 2 2 2 0 Insect antifreeze protein repeat 2Fe-2S_thioredx PF01257.19 AMK77800.1 - 2.6e-06 27.3 0.1 3.4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Suc_Fer-like PF06999.12 AMK77800.1 - 0.00027 20.9 0.0 0.00078 19.4 0.0 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Brr6_like_C_C PF10104.9 AMK77800.1 - 0.034 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF1636 PF07845.11 AMK77800.1 - 0.084 13.3 0.0 0.095 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) DUF364 PF04016.12 AMK77803.1 - 6.8e-39 132.8 0.0 9.6e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 Putative heavy-metal chelation DUF4213 PF13938.6 AMK77803.1 - 3.8e-17 62.3 0.1 6e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Putative heavy-metal chelation CCG PF02754.16 AMK77805.1 - 5.4e-26 90.6 2.8 4.3e-13 49.3 0.8 2.5 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 AMK77805.1 - 1.1e-09 38.6 7.5 2.5e-09 37.4 7.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK77805.1 - 3.4e-09 37.1 7.7 7.4e-09 36.1 7.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK77805.1 - 3.5e-09 37.1 7.9 8.7e-09 35.8 7.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK77805.1 - 4.3e-08 33.1 9.4 0.00084 19.7 1.2 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AMK77805.1 - 1.1e-07 31.8 8.6 4.5e-07 29.9 8.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AMK77805.1 - 4.2e-07 29.5 10.5 0.0014 18.3 2.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AMK77805.1 - 2.8e-06 27.4 8.5 8.1e-06 25.9 7.9 2.2 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK77805.1 - 4e-06 26.6 15.0 0.01 15.9 3.9 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AMK77805.1 - 9.1e-06 25.5 10.7 0.0007 19.6 1.5 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AMK77805.1 - 1e-05 26.4 6.5 2.6e-05 25.1 6.5 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AMK77805.1 - 7.9e-05 23.4 4.7 0.12 13.3 0.5 3.4 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK77805.1 - 0.00055 20.0 5.7 0.33 11.1 0.8 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AMK77805.1 - 0.0043 17.6 5.4 0.53 10.9 0.7 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AMK77805.1 - 0.16 12.9 18.3 0.8 10.8 4.4 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 AMK77805.1 - 0.38 11.5 3.1 2 9.2 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AMK77805.1 - 0.89 9.8 10.3 2 8.6 2.2 2.3 1 1 0 2 2 2 0 4Fe-4S dicluster domain RloB PF13707.6 AMK77806.1 - 8.7e-11 42.4 0.1 1e-10 42.1 0.1 1.0 1 0 0 1 1 1 1 RloB-like protein Glyco_tranf_2_4 PF13704.6 AMK77806.1 - 0.033 14.7 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 AAA_21 PF13304.6 AMK77807.1 - 1.5e-28 100.5 0.1 1.9e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AMK77807.1 - 4e-10 39.9 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AMK77807.1 - 0.021 14.3 0.2 0.7 9.3 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AMK77807.1 - 0.024 14.9 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AMK77807.1 - 0.04 14.4 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_transf PF02397.16 AMK77808.1 - 6.3e-67 224.8 0.0 1.1e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 AMK77808.1 - 1.3e-22 80.7 6.5 2.6e-22 79.7 6.5 1.5 1 0 0 1 1 1 1 CoA-binding domain GFO_IDH_MocA PF01408.22 AMK77808.1 - 0.17 12.7 0.0 0.31 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF3995 PF13160.6 AMK77808.1 - 8.1 6.8 17.1 0.23 11.8 8.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Poly_export PF02563.16 AMK77809.1 - 2.3e-27 95.0 0.0 1.7e-26 92.2 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AMK77809.1 - 6.7e-10 38.7 0.1 9.3e-08 31.8 0.1 2.5 2 0 0 2 2 2 2 SLBB domain Wza_C PF18412.1 AMK77809.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain GNVR PF13807.6 AMK77810.1 - 7.2e-29 99.6 0.0 1.5e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase AAA_31 PF13614.6 AMK77810.1 - 3.8e-13 49.7 0.2 4.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Wzz PF02706.15 AMK77810.1 - 4.4e-10 39.7 0.0 1.7e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 Chain length determinant protein CbiA PF01656.23 AMK77810.1 - 2.5e-08 34.0 0.0 9.2e-08 32.2 0.0 2.0 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AMK77810.1 - 9.9e-06 25.2 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 AMK77810.1 - 1.7e-05 24.4 0.3 4.2e-05 23.1 0.3 1.7 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AMK77810.1 - 0.021 14.3 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 AMK77810.1 - 0.036 13.9 0.0 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain Occludin_ELL PF07303.13 AMK77810.1 - 0.042 14.6 2.7 0.52 11.1 0.7 2.5 2 0 0 2 2 2 0 Occludin homology domain ArsA_ATPase PF02374.15 AMK77810.1 - 0.054 12.7 0.8 0.21 10.7 0.0 2.3 3 0 0 3 3 3 0 Anion-transporting ATPase SKA2 PF16740.5 AMK77810.1 - 0.12 12.2 5.5 0.38 10.6 5.5 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AAA_25 PF13481.6 AMK77810.1 - 0.12 11.9 0.1 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain V-SNARE_C PF12352.8 AMK77810.1 - 0.16 12.3 0.8 0.56 10.5 0.8 2.0 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Wzy_C PF04932.15 AMK77811.1 - 6.7e-08 32.3 1.3 6.7e-08 32.3 1.3 3.2 4 1 0 4 4 4 1 O-Antigen ligase Polysacc_synt PF01943.17 AMK77812.1 - 1.2e-09 38.0 13.0 1.2e-09 38.0 13.0 2.5 1 1 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 AMK77812.1 - 3.2e-05 24.0 1.1 3.2e-05 24.0 1.1 4.7 4 1 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 AMK77812.1 - 0.0044 16.3 16.1 0.014 14.7 13.5 2.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein UCR_6-4kD PF08997.10 AMK77812.1 - 0.044 13.7 3.1 0.27 11.2 0.7 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Methyltransf_23 PF13489.6 AMK77813.1 - 1.8e-13 50.7 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77813.1 - 5.7e-09 36.5 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77813.1 - 8.2e-06 26.5 0.0 3.9e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK77813.1 - 0.00016 21.5 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK77813.1 - 0.0045 17.7 0.0 0.041 14.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 AMK77813.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Glycos_transf_2 PF00535.26 AMK77814.1 - 7.2e-15 55.2 0.0 9.6e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 AMK77814.1 - 8.9e-05 22.9 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK77814.1 - 0.00031 20.7 0.0 0.00038 20.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AMK77815.1 - 9.6e-17 61.3 0.2 1.6e-16 60.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK77815.1 - 5.4e-08 33.0 0.0 8.3e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK77815.1 - 2.7e-05 23.8 0.8 0.00015 21.4 0.2 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 5TM-5TMR_LYT PF07694.12 AMK77815.1 - 0.064 12.8 0.3 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT EF-hand_5 PF13202.6 AMK77815.1 - 0.07 12.7 0.3 0.19 11.3 0.3 1.7 1 0 0 1 1 1 0 EF hand Glycos_transf_1 PF00534.20 AMK77816.1 - 1.8e-15 56.9 0.0 3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK77816.1 - 8.2e-15 55.4 0.1 1.9e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK77816.1 - 2.8e-12 47.4 3.6 5e-12 46.5 3.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 AMK77816.1 - 1.3e-11 44.8 1.0 1.9e-11 44.2 1.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_tranf_2_3 PF13641.6 AMK77817.1 - 2.7e-14 53.6 0.0 3.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AMK77817.1 - 4e-13 49.5 0.0 6.5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AMK77817.1 - 0.00013 21.5 0.1 0.00026 20.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AMK77817.1 - 0.00014 21.8 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 NTP_transf_3 PF12804.7 AMK77817.1 - 0.0022 18.4 0.1 0.0054 17.1 0.1 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain Glyco_tranf_2_5 PF13712.6 AMK77817.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family YscK PF06578.12 AMK77817.1 - 0.042 13.4 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Acetyltransf_5 PF13444.6 AMK77818.1 - 8.9e-17 61.7 0.6 1.7e-16 60.7 0.4 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 AMK77818.1 - 0.001 18.6 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 2 Autoinducer synthase LCCL PF03815.19 AMK77819.1 - 1.8e-21 76.0 0.4 2.7e-21 75.5 0.4 1.2 1 0 0 1 1 1 1 LCCL domain Rxt3 PF08642.10 AMK77819.1 - 0.0047 17.7 0.2 0.025 15.4 0.0 2.1 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 Phage_holin_3_6 PF07332.11 AMK77819.1 - 0.14 12.2 2.4 0.22 11.5 2.4 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III OAD_gamma PF04277.13 AMK77819.1 - 2.6 8.7 6.5 20 5.9 0.4 2.6 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain HH_signal PF01085.18 AMK77820.1 - 0.0034 17.0 0.2 9.2 5.9 0.0 3.1 3 0 0 3 3 3 1 Hedgehog amino-terminal signalling domain Mgr1 PF08602.10 AMK77820.1 - 0.013 14.4 0.3 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit NPV_P10 PF05531.12 AMK77820.1 - 0.041 14.3 11.2 8.6 6.9 1.2 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YpjP PF14005.6 AMK77820.1 - 0.045 13.8 0.9 0.14 12.2 0.9 1.8 1 0 0 1 1 1 0 YpjP-like protein DUF4201 PF13870.6 AMK77820.1 - 0.083 12.6 19.2 0.18 11.5 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF2756 PF10956.8 AMK77820.1 - 0.17 12.4 9.8 3 8.4 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) Baculo_PEP_C PF04513.12 AMK77820.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 AMK77820.1 - 0.69 10.0 6.2 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1216 PF06746.11 AMK77820.1 - 3.1 7.8 8.2 1.2 9.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) T7SS_ESX_EspC PF10824.8 AMK77820.1 - 3.9 8.0 11.2 2.4 8.7 0.2 3.5 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Response_reg PF00072.24 AMK77822.1 - 7.3e-32 109.9 0.0 1.8e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_C14 PF00656.22 AMK77824.1 - 7.1e-23 81.8 1.9 1.4e-22 80.9 0.0 2.2 2 1 0 2 2 2 1 Caspase domain Sel1 PF08238.12 AMK77824.1 - 1.2e-14 54.4 11.2 5.6e-07 30.0 0.1 3.0 3 0 0 3 3 3 2 Sel1 repeat Filament PF00038.21 AMK77824.1 - 0.0019 17.8 33.2 0.0094 15.6 33.1 2.0 1 1 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 AMK77824.1 - 0.0021 17.4 34.6 0.0021 17.4 34.6 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 AMK77824.1 - 0.0066 15.6 37.1 0.22 10.6 4.6 2.6 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_C13 PF01650.18 AMK77824.1 - 0.026 14.0 0.1 0.81 9.2 0.0 2.5 2 0 0 2 2 2 0 Peptidase C13 family Peptidase_C23 PF05379.11 AMK77824.1 - 0.061 13.5 0.1 5.5 7.2 0.0 2.6 1 1 1 2 2 2 0 Carlavirus endopeptidase Golgin_A5 PF09787.9 AMK77824.1 - 0.65 9.4 40.2 0.048 13.1 28.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3584 PF12128.8 AMK77824.1 - 0.65 7.4 34.0 0.99 6.8 34.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 AMK77824.1 - 0.81 9.3 44.3 0.027 14.1 32.7 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 AMK77824.1 - 2.6 7.4 38.7 1.8 8.0 21.1 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 AMK77824.1 - 2.9 8.1 27.1 0.32 11.2 8.2 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 AMK77824.1 - 3 8.2 38.8 1.8 9.0 10.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 AMK77824.1 - 3.5 6.4 42.6 2.1 7.2 24.9 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Leu_zip PF15294.6 AMK77824.1 - 5.4 6.5 34.9 1.8 8.0 7.6 2.4 1 1 2 3 3 3 0 Leucine zipper Abhydrolase_6 PF12697.7 AMK77825.1 - 5.1e-07 30.5 4.6 4.2e-05 24.2 1.5 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AMK77825.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AMK77825.1 - 0.00056 19.2 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 AMK77825.1 - 0.00083 19.1 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 AMK77825.1 - 0.0029 17.5 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF3089 PF11288.8 AMK77825.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.13 AMK77825.1 - 0.02 14.6 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.11 AMK77825.1 - 0.022 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 AMK77825.1 - 0.072 12.2 0.0 0.14 11.2 0.0 1.4 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DLH PF01738.18 AMK77825.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Thioesterase PF00975.20 AMK77825.1 - 0.11 12.6 0.1 0.34 11.0 0.1 1.7 1 1 1 2 2 2 0 Thioesterase domain Say1_Mug180 PF10340.9 AMK77825.1 - 0.12 11.3 0.3 0.36 9.6 0.3 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase DUF1057 PF06342.12 AMK77825.1 - 0.28 10.2 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Autotransporter PF03797.19 AMK77826.1 - 8e-52 176.4 23.0 1.2e-51 175.8 23.0 1.3 1 0 0 1 1 1 1 Autotransporter beta-domain PPC PF04151.15 AMK77826.1 - 0.006 17.6 2.8 0.006 17.6 2.8 2.4 2 0 0 2 2 2 1 Bacterial pre-peptidase C-terminal domain Pkinase PF00069.25 AMK77827.1 - 1.5e-40 139.3 0.0 3.9e-39 134.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AMK77827.1 - 2e-24 86.3 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 AMK77827.1 - 0.00022 21.2 0.0 0.0014 18.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family TPR_2 PF07719.17 AMK77827.1 - 0.0072 16.4 2.5 2.2 8.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 AMK77827.1 - 0.026 14.3 1.6 29 4.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat P53_tetramer PF07710.11 AMK77827.1 - 0.13 11.6 0.1 14 5.1 0.0 2.6 2 0 0 2 2 2 0 P53 tetramerisation motif RIO1 PF01163.22 AMK77827.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF3683 PF12447.8 AMK77828.1 - 1.5e-49 166.8 0.6 3.5e-49 165.7 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) FAD_binding_4 PF01565.23 AMK77828.1 - 1.9e-24 86.0 1.3 9.3e-24 83.7 0.6 2.5 3 0 0 3 3 3 1 FAD binding domain FAD-oxidase_C PF02913.19 AMK77828.1 - 2e-24 86.6 5.0 3.4e-17 62.9 0.6 3.0 3 0 0 3 3 3 2 FAD linked oxidases, C-terminal domain DUF3400 PF11880.8 AMK77828.1 - 9.5e-18 63.5 1.4 2.8e-17 62.0 1.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3400) CCG PF02754.16 AMK77828.1 - 2e-14 53.5 0.8 7.9e-07 29.2 0.1 3.1 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 AMK77828.1 - 4.3e-06 27.1 2.9 4.3e-06 27.1 2.9 2.6 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK77828.1 - 6.8e-05 23.4 3.9 6.8e-05 23.4 3.9 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK77828.1 - 0.00016 21.8 6.5 0.0032 17.6 0.3 2.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK77828.1 - 0.00018 22.0 7.3 0.0048 17.4 8.0 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AMK77828.1 - 0.0024 18.1 4.4 0.36 11.0 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain IKBKB_SDD PF18397.1 AMK77828.1 - 0.025 13.9 0.1 1.1 8.5 0.1 2.2 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain Fer4_9 PF13187.6 AMK77828.1 - 0.15 12.3 15.2 0.019 15.1 7.6 3.1 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK77828.1 - 0.22 11.7 17.1 0.16 12.1 1.5 3.1 3 1 1 4 4 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK77828.1 - 1.3 10.0 11.3 2.6 9.0 8.6 2.8 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Cytochrom_C_2 PF01322.20 AMK77828.1 - 3.6 8.5 5.0 34 5.3 0.2 2.7 2 0 0 2 2 2 0 Cytochrome C' Fer4 PF00037.27 AMK77828.1 - 8.9 6.3 19.5 2.9 7.8 3.7 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain OEP PF02321.18 AMK77830.1 - 1.1e-61 207.9 37.0 3e-33 115.2 12.5 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_D23 PF16576.5 AMK77831.1 - 1.2e-19 70.4 0.4 1.9e-19 69.8 0.4 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK77831.1 - 4.9e-13 49.7 0.2 7.1e-11 42.8 0.0 2.7 3 0 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK77831.1 - 4.8e-10 39.1 0.5 4.8e-10 39.1 0.5 2.8 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD PF00529.20 AMK77831.1 - 0.027 14.4 6.6 1 9.3 6.5 2.8 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS RnfC_N PF13375.6 AMK77831.1 - 0.1 12.6 0.3 23 5.0 0.0 2.9 3 1 0 3 3 3 0 RnfC Barrel sandwich hybrid domain ACR_tran PF00873.19 AMK77832.1 - 1.8e-148 496.0 10.4 2.5e-105 353.2 8.7 2.0 1 1 1 2 2 2 2 AcrB/AcrD/AcrF family VirB8 PF04335.13 AMK77832.1 - 0.56 10.0 2.9 0.8 9.5 0.1 2.3 2 0 0 2 2 2 0 VirB8 protein Y1_Tnp PF01797.16 AMK77833.1 - 7.4e-09 35.8 0.2 9.9e-09 35.3 0.2 1.2 1 0 0 1 1 1 1 Transposase IS200 like DUF3616 PF12275.8 AMK77835.1 - 5.8e-14 52.2 0.2 3.2e-06 26.8 0.0 2.7 1 1 0 2 2 2 2 Protein of unknown function (DUF3616) MIP PF00230.20 AMK77836.1 - 1.2e-49 169.1 18.0 1.4e-49 168.9 18.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DRAT PF07357.11 AMK77837.1 - 8.5e-103 343.0 0.1 9.6e-103 342.8 0.1 1.0 1 0 0 1 1 1 1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) ADP_ribosyl_GH PF03747.14 AMK77838.1 - 2.8e-59 201.2 1.5 3.8e-58 197.5 1.5 1.9 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase VIT1 PF01988.19 AMK77839.1 - 1.5e-55 188.4 16.4 1.7e-55 188.2 16.4 1.0 1 0 0 1 1 1 1 VIT family PP-binding PF00550.25 AMK77841.1 - 4.7e-16 58.9 0.4 5.2e-16 58.8 0.4 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AMK77841.1 - 1.8e-05 24.8 0.9 2.1e-05 24.7 0.9 1.3 1 1 0 1 1 1 1 Acyl-carrier DUF1896 PF08989.10 AMK77841.1 - 0.057 13.5 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) HLH PF00010.26 AMK77841.1 - 0.059 13.3 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DUF1493 PF07377.12 AMK77841.1 - 0.079 13.4 0.4 0.088 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) ketoacyl-synt PF00109.26 AMK77842.1 - 7.7e-58 196.0 2.3 8.3e-58 195.9 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AMK77842.1 - 1.4e-37 128.3 1.5 2.6e-37 127.5 1.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AMK77842.1 - 3.1e-07 30.0 0.4 2.7e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AMK77842.1 - 0.019 14.8 1.7 0.68 9.8 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NTPase_P4 PF11602.8 AMK77842.1 - 0.055 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 KAsynt_C_assoc PF16197.5 AMK77842.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Aminotran_4 PF01063.19 AMK77843.1 - 5e-48 163.9 0.0 5.8e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV YceG PF02618.16 AMK77844.1 - 9.5e-87 291.0 0.0 1.1e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 YceG-like family GCD14_N PF14801.6 AMK77844.1 - 0.18 11.7 0.8 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term GN3L_Grn1 PF08701.11 AMK77844.1 - 0.19 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Thymidylate_kin PF02223.17 AMK77845.1 - 5.8e-53 179.3 0.0 6.6e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AMK77845.1 - 1.3e-08 35.3 0.1 1.6e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK77845.1 - 0.0039 17.5 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AMK77845.1 - 0.006 16.8 0.0 0.0077 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 AMK77845.1 - 0.011 15.6 0.2 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 Helicase AAA_30 PF13604.6 AMK77845.1 - 0.035 13.8 0.2 0.066 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2007 PF09413.10 AMK77845.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein AAA_17 PF13207.6 AMK77845.1 - 0.11 13.0 0.1 2.1 8.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 AMK77845.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 NTPase Docking PF08990.11 AMK77845.1 - 3.4 7.4 7.2 1.7 8.3 0.5 2.4 2 0 0 2 2 2 0 Erythronolide synthase docking DNA_pol3_delta2 PF13177.6 AMK77846.1 - 1.6e-43 148.3 0.0 3e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 AMK77846.1 - 1.5e-16 61.0 9.9 1.6e-16 60.8 8.9 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal DNA_pol3_gamma3 PF12169.8 AMK77846.1 - 0.0047 16.8 1.9 0.0047 16.8 1.9 1.7 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III AAA_16 PF13191.6 AMK77846.1 - 0.011 16.2 0.4 0.098 13.0 0.4 2.5 1 1 0 1 1 1 0 AAA ATPase domain YAcAr PF10686.9 AMK77846.1 - 0.11 12.5 0.4 32 4.6 0.0 3.4 3 1 1 4 4 4 0 YspA, cpYpsA-related SLOG family PilZ PF07238.14 AMK77847.1 - 7.6e-10 39.0 0.0 9.1e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 PilZ domain TatD_DNase PF01026.21 AMK77848.1 - 4.7e-73 245.7 0.0 5.3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase MTS PF05175.14 AMK77849.1 - 8.5e-58 194.6 0.1 3.5e-56 189.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AMK77849.1 - 4.5e-13 49.7 0.0 9.8e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK77849.1 - 6.9e-12 45.4 0.1 1.3e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77849.1 - 4.8e-09 36.9 0.0 1.2e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77849.1 - 1.4e-08 35.3 0.0 2.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AMK77849.1 - 4.9e-07 29.4 0.0 3.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 AMK77849.1 - 6.1e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AMK77849.1 - 0.00046 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AMK77849.1 - 0.00084 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 AMK77849.1 - 0.002 17.6 0.1 0.018 14.5 0.1 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 AMK77849.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 AMK77849.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 AMK77849.1 - 0.029 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Glycos_transf_2 PF00535.26 AMK77850.1 - 1.2e-29 103.3 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK77850.1 - 5.8e-08 32.9 0.0 1e-07 32.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK77850.1 - 0.0001 22.7 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK77850.1 - 0.0004 19.9 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AMK77850.1 - 0.00094 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 AMK77850.1 - 0.0011 19.3 0.0 0.0016 18.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain SPC25 PF06703.11 AMK77850.1 - 0.048 13.5 0.4 0.079 12.7 0.4 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) HAGH_C PF16123.5 AMK77851.1 - 1.3e-24 86.5 0.1 2.1e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 AMK77851.1 - 1.1e-23 84.3 0.1 2.2e-22 80.0 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK77851.1 - 0.044 13.3 0.9 0.15 11.5 0.9 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DXP_synthase_N PF13292.6 AMK77852.1 - 2e-122 407.7 0.0 4.2e-122 406.6 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AMK77852.1 - 9.1e-37 126.4 0.0 2.1e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AMK77852.1 - 1.9e-29 102.0 0.2 5.5e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AMK77852.1 - 3.5e-06 26.9 0.7 2.1e-05 24.3 0.3 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AMK77852.1 - 1.4e-05 24.2 0.1 2.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 AMK77852.1 - 0.00015 20.8 0.0 0.0034 16.4 0.0 2.2 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain CopD PF05425.13 AMK77853.1 - 6.6e-13 49.0 9.7 6.6e-13 49.0 9.7 4.3 4 1 1 5 5 5 1 Copper resistance protein D CopC PF04234.12 AMK77854.1 - 2.7e-09 38.0 0.0 3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 CopC domain Peptidase_M61_N PF17899.1 AMK77854.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain Aminotran_3 PF00202.21 AMK77855.1 - 6.1e-100 334.7 0.0 8.5e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PNP_UDP_1 PF01048.20 AMK77856.1 - 7.5e-24 84.3 0.0 2.4e-22 79.3 0.0 2.6 1 1 0 1 1 1 1 Phosphorylase superfamily SQHop_cyclase_C PF13243.6 AMK77857.1 - 2.1e-141 470.6 5.4 1.4e-135 451.6 6.0 3.8 3 1 1 4 4 4 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 AMK77857.1 - 2.1e-122 407.8 0.9 1.6e-114 381.9 0.0 4.2 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 AMK77857.1 - 4.5e-25 87.1 14.8 6.5e-10 38.6 0.1 7.8 9 0 0 9 9 9 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 AMK77857.1 - 0.0007 18.7 0.2 2.7 6.9 0.1 4.7 4 1 2 6 6 6 1 A-macroglobulin TED domain Pec_lyase PF09492.10 AMK77857.1 - 0.079 12.3 0.6 6.5 6.0 0.2 3.3 3 1 0 3 3 3 0 Pectic acid lyase Bd3614_N PF14442.6 AMK77857.1 - 0.085 13.2 0.4 21 5.5 0.0 3.3 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal SQS_PSY PF00494.19 AMK77858.1 - 6.1e-51 173.4 0.0 1.5e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Squalene/phytoene synthase DUF3463 PF11946.8 AMK77859.1 - 1.8e-55 186.4 0.1 2.7e-55 185.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) Radical_SAM PF04055.21 AMK77859.1 - 4e-15 56.6 0.1 5.8e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AMK77859.1 - 0.00032 20.8 0.0 0.00076 19.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK77859.1 - 0.01 16.1 0.0 0.036 14.3 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain HMGL-like PF00682.19 AMK77859.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 HMGL-like MlaC PF05494.12 AMK77860.1 - 5.5e-39 133.6 0.3 6.5e-39 133.4 0.3 1.0 1 0 0 1 1 1 1 MlaC protein DUF4864 PF16156.5 AMK77860.1 - 0.053 14.2 0.0 0.081 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) MlaA PF04333.13 AMK77861.1 - 2.8e-71 239.3 0.2 3.6e-71 238.9 0.2 1.1 1 0 0 1 1 1 1 MlaA lipoprotein Pribosyltran PF00156.27 AMK77862.1 - 4.8e-13 48.9 0.0 6.4e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AMK77862.1 - 0.0041 16.6 0.0 0.005 16.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pox_A_type_inc PF04508.12 AMK77862.1 - 0.37 10.7 1.6 0.69 9.9 1.6 1.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DXP_synthase_N PF13292.6 AMK77863.1 - 1.8e-122 407.8 0.0 4.2e-122 406.6 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AMK77863.1 - 9.3e-37 126.4 0.0 2e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AMK77863.1 - 2.8e-30 104.8 0.2 7.7e-30 103.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AMK77863.1 - 3.5e-06 26.9 0.7 2.1e-05 24.3 0.3 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AMK77863.1 - 1.4e-05 24.2 0.1 2.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 AMK77863.1 - 0.00015 20.8 0.0 0.0034 16.4 0.0 2.2 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain polyprenyl_synt PF00348.17 AMK77864.1 - 7.1e-55 185.8 0.4 8.7e-55 185.5 0.4 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Exonuc_VII_S PF02609.16 AMK77865.1 - 4.7e-22 77.8 6.0 6.7e-22 77.3 6.0 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit Oscp1 PF10188.9 AMK77865.1 - 0.0042 17.2 0.2 0.0045 17.1 0.2 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 GRDB PF07355.12 AMK77865.1 - 0.025 13.8 0.3 0.025 13.8 0.3 1.0 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) KxDL PF10241.9 AMK77865.1 - 0.029 14.7 2.7 0.036 14.3 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF5304 PF17230.2 AMK77865.1 - 0.036 14.3 0.3 0.039 14.2 0.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5304) DASH_Dad2 PF08654.10 AMK77865.1 - 0.036 14.5 0.2 0.044 14.2 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 V-SNARE PF05008.15 AMK77865.1 - 0.072 13.5 2.3 0.072 13.5 2.3 2.2 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TPR_2 PF07719.17 AMK77865.1 - 0.078 13.1 0.1 20 5.6 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat OmpH PF03938.14 AMK77865.1 - 0.51 10.7 5.9 0.58 10.5 5.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DNA_gyraseB PF00204.25 AMK77866.1 - 2.2e-39 134.7 0.0 5.3e-39 133.5 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AMK77866.1 - 3.9e-25 87.8 1.0 7e-25 87.0 1.0 1.4 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AMK77866.1 - 9.1e-19 68.0 0.3 1.8e-18 67.0 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AMK77866.1 - 8.3e-13 48.4 0.1 3.1e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Toprim domain TOPRIM_C PF16898.5 AMK77866.1 - 0.00072 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM HATPase_c_3 PF13589.6 AMK77866.1 - 0.0011 18.8 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CvfB_WH PF17783.1 AMK77868.1 - 2.2e-24 85.0 0.2 1.1e-23 82.8 0.1 2.0 2 0 0 2 2 2 1 CvfB-like winged helix domain S1_2 PF13509.6 AMK77868.1 - 8.8e-22 76.9 0.0 7.9e-15 54.7 0.2 3.3 3 0 0 3 3 3 2 S1 domain Cytochrome_P460 PF16694.5 AMK77869.1 - 1.1e-32 113.0 0.0 1.3e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P460 LigD_N PF13298.6 AMK77869.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Porin_7 PF16956.5 AMK77869.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative general bacterial porin Fae PF08714.11 AMK77870.1 - 1.6e-59 200.4 0.5 1.8e-59 200.2 0.5 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Putative_PNPOx PF01243.20 AMK77871.1 - 3e-13 49.8 0.0 5.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4336 PF14234.6 AMK77872.1 - 9.1e-21 74.4 0.3 8.9e-16 58.0 0.0 3.0 2 1 1 3 3 3 3 Domain of unknown function (DUF4336) PAPS_reduct PF01507.19 AMK77874.1 - 3.8e-47 160.6 0.0 4.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HHH_9 PF17674.1 AMK77874.1 - 0.0038 18.1 0.0 0.0079 17.1 0.0 1.5 1 0 0 1 1 1 1 HHH domain DpnI_C PF17726.1 AMK77874.1 - 0.1 12.8 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Dam-replacing HTH domain Citrate_bind PF16114.5 AMK77874.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Ppx-GppA PF02541.16 AMK77874.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Glu_cys_ligase PF04262.14 AMK77875.1 - 7.1e-163 541.5 0.0 8.6e-163 541.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase CcdB PF01845.17 AMK77876.1 - 3.9e-29 100.8 0.0 4.3e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 CcdB protein CcdA PF07362.12 AMK77877.1 - 1.5e-28 99.0 1.4 1.7e-28 98.8 1.4 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA DHR10 PF18595.1 AMK77877.1 - 0.00031 20.8 4.5 0.00036 20.6 4.5 1.0 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain LolB PF03550.14 AMK77877.1 - 0.029 14.4 1.4 0.034 14.2 1.4 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB IF-2B PF01008.17 AMK77877.1 - 0.11 11.7 0.4 0.12 11.6 0.4 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family RQC PF09382.10 AMK77878.1 - 3.6e-40 136.3 0.1 1.2e-39 134.7 0.0 1.9 2 0 0 2 2 2 1 RQC domain HRDC PF00570.23 AMK77878.1 - 3.2e-22 78.3 0.0 8e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.31 AMK77878.1 - 1.6e-21 76.7 0.0 1.6e-17 63.9 0.0 3.5 4 0 0 4 4 4 2 Helicase conserved C-terminal domain DEAD PF00270.29 AMK77878.1 - 8.4e-20 71.3 0.0 1.5e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 AMK77878.1 - 8.8e-20 71.2 1.4 2.3e-19 69.8 1.4 1.8 1 0 0 1 1 1 1 RecQ zinc-binding HTH_40 PF14493.6 AMK77878.1 - 2.2e-18 66.5 0.0 5.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AMK77878.1 - 0.015 14.9 0.5 2.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Sigma-70, region 4 ResIII PF04851.15 AMK77878.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HTH_22 PF13309.6 AMK77878.1 - 0.047 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 HTH domain GerE PF00196.19 AMK77878.1 - 0.081 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF1249 PF06853.12 AMK77879.1 - 2.4e-31 108.2 0.1 2.8e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1249) PTPS PF01242.19 AMK77880.1 - 1.5e-33 115.3 0.2 1.7e-33 115.2 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Nodulin-like PF06813.13 AMK77880.1 - 0.19 11.2 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Nodulin-like PilZ PF07238.14 AMK77881.1 - 7.6e-07 29.4 0.0 8.5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 PilZ domain SCAB-Ig PF16709.5 AMK77881.1 - 0.023 14.7 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein tRNA-synt_1b PF00579.25 AMK77882.1 - 4.4e-56 190.4 0.0 5.8e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 AMK77882.1 - 0.098 11.6 0.0 0.28 10.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF218 PF02698.17 AMK77883.1 - 1.1e-24 87.0 0.0 1.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain ABC_tran PF00005.27 AMK77884.1 - 2.9e-32 112.1 0.0 4.9e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AMK77884.1 - 1e-15 58.1 6.2 1.5e-15 57.6 6.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AMK77884.1 - 1.8e-05 24.3 1.0 0.00016 21.2 1.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AMK77884.1 - 0.004 17.1 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 AMK77884.1 - 0.0043 17.1 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 AMK77884.1 - 0.0053 17.2 0.1 0.015 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 AMK77884.1 - 0.025 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 AMK77884.1 - 0.031 14.6 0.0 0.42 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 AMK77884.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 AMK77884.1 - 0.075 12.8 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 AMK77884.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 AMK77884.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AhpC-TSA PF00578.21 AMK77885.1 - 5.3e-33 113.6 0.1 6.3e-33 113.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK77885.1 - 1.2e-20 73.8 0.0 1.4e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 AMK77885.1 - 0.0047 17.0 0.0 0.0065 16.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 AMK77885.1 - 0.008 15.7 0.0 0.0087 15.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) DUF3110 PF11360.8 AMK77885.1 - 0.15 12.3 0.0 0.94 9.7 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3110) Response_reg PF00072.24 AMK77886.1 - 9.3e-25 87.0 0.0 1.4e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK77886.1 - 4.8e-18 65.0 0.5 1.3e-17 63.7 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 AMK77886.1 - 0.0099 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Prim-Pol PF09250.11 AMK77886.1 - 0.05 14.0 0.0 0.07 13.5 0.0 1.4 1 1 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal 2CSK_N PF08521.10 AMK77887.1 - 4.1e-38 130.6 0.1 9.6e-38 129.4 0.1 1.7 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal HATPase_c PF02518.26 AMK77887.1 - 1.5e-20 73.7 0.0 2.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK77887.1 - 5.4e-10 39.2 2.2 4.9e-09 36.1 0.6 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK77887.1 - 4.5e-07 30.1 1.8 5.3e-06 26.7 0.5 2.7 2 0 0 2 2 2 1 HAMP domain PspA_IM30 PF04012.12 AMK77887.1 - 0.00076 19.1 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 PspA/IM30 family BLOC1S3 PF15753.5 AMK77887.1 - 0.023 14.8 0.2 0.066 13.3 0.1 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 HATPase_c_2 PF13581.6 AMK77887.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pro_CA PF00484.19 AMK77888.1 - 5.4e-49 166.5 0.2 6.5e-49 166.2 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Adeno_E3 PF06040.11 AMK77889.1 - 0.81 9.9 5.8 2.3 8.4 1.0 2.2 2 0 0 2 2 2 0 Adenovirus E3 protein Rib_5-P_isom_A PF06026.14 AMK77890.1 - 1.7e-52 177.5 0.0 2e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AMK77890.1 - 6.8e-09 35.9 0.0 1.4e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 AMK77890.1 - 0.096 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain CoA_trans PF01144.23 AMK77890.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Hexapep PF00132.24 AMK77891.1 - 2e-27 93.9 36.9 7.5e-10 38.1 7.1 5.4 5 0 0 5 5 5 5 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 AMK77891.1 - 7.9e-13 48.0 0.0 2.1e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 AMK77891.1 - 1.6e-07 30.9 33.0 5.4e-05 22.9 3.8 5.8 5 1 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase Spermine_synth PF01564.17 AMK77892.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 AMK77892.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 AMK77892.1 - 0.11 13.6 0.0 0.21 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AMK77892.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Wzy_C PF04932.15 AMK77892.1 - 0.23 11.1 12.3 1.5 8.5 0.0 4.4 2 1 1 3 3 3 0 O-Antigen ligase Peptidase_M74 PF03411.13 AMK77893.1 - 2.3e-13 50.3 0.0 3.3e-13 49.8 0.0 1.2 1 1 0 1 1 1 1 Penicillin-insensitive murein endopeptidase Aldedh PF00171.22 AMK77894.1 - 6.3e-25 87.6 1.7 1.1e-15 57.2 0.9 2.1 1 1 0 2 2 2 2 Aldehyde dehydrogenase family Viral_Beta_CD PF04530.12 AMK77895.1 - 0.014 15.7 0.3 0.038 14.3 0.1 1.6 1 1 0 1 1 1 0 Viral Beta C/D like family Glyoxalase PF00903.25 AMK77898.1 - 1.5e-10 41.3 0.0 1.9e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 AMK77898.1 - 9.1e-06 26.4 0.1 2.4e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 AMK77898.1 - 0.005 16.8 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain p450 PF00067.22 AMK77899.1 - 2e-84 284.0 0.0 2.5e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Response_reg PF00072.24 AMK77900.1 - 7.7e-46 154.9 0.6 3.1e-24 85.3 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.7 AMK77900.1 - 2.6e-41 140.1 0.0 2.2e-17 63.2 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AMK77900.1 - 6.9e-36 122.7 0.1 7.5e-17 61.4 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 AMK77900.1 - 4.5e-34 117.0 0.0 1.6e-15 57.3 0.0 3.6 3 0 0 3 3 3 3 PAS fold HATPase_c PF02518.26 AMK77900.1 - 7e-27 94.2 0.0 1.3e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AMK77900.1 - 1.5e-24 85.5 0.0 2.2e-07 30.7 0.0 4.5 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 AMK77900.1 - 7.4e-24 83.9 0.0 2.1e-07 31.1 0.0 3.9 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 AMK77900.1 - 1.9e-20 72.7 1.3 2.4e-19 69.1 0.4 3.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AMK77900.1 - 5.4e-11 42.6 5.6 5.4e-11 42.6 5.6 3.4 4 0 0 4 4 3 1 Hpt domain MEKHLA PF08670.11 AMK77900.1 - 0.022 14.7 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 MEKHLA domain Phage_Nu1 PF07471.12 AMK77900.1 - 0.027 14.3 2.0 0.03 14.1 0.1 2.0 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 CREPT PF16566.5 AMK77900.1 - 0.57 10.3 10.1 2.1 8.5 0.3 3.8 4 0 0 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3197 PF11432.8 AMK77901.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) PEP-CTERM PF07589.11 AMK77902.1 - 0.065 13.3 0.5 0.14 12.2 0.5 1.6 1 0 0 1 1 1 0 PEP-CTERM motif GSDH PF07995.11 AMK77903.1 - 1.1e-39 136.7 0.1 7e-34 117.6 0.0 3.6 1 1 1 2 2 2 2 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 AMK77903.1 - 0.14 12.5 0.2 61 4.4 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller NUDIX PF00293.28 AMK77904.1 - 1.4e-13 51.0 0.5 2e-13 50.5 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain GSDH PF07995.11 AMK77905.1 - 2.1e-16 60.2 0.0 5.8e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PQQ_3 PF13570.6 AMK77905.1 - 4.3e-05 23.8 0.1 0.01 16.3 0.1 3.0 2 0 0 2 2 2 1 PQQ-like domain SGL PF08450.12 AMK77905.1 - 4.7e-05 23.1 0.0 0.00034 20.3 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 AMK77905.1 - 0.0033 17.4 0.1 0.5 10.5 0.0 3.6 4 0 0 4 4 4 1 NHL repeat Peptidase_M48 PF01435.18 AMK77906.1 - 1.3e-38 132.8 0.1 2.1e-38 132.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AMK77906.1 - 0.00032 20.0 0.0 0.00082 18.7 0.0 1.6 1 1 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M1 PF01433.20 AMK77906.1 - 0.013 15.0 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain DUF3104 PF11302.8 AMK77906.1 - 0.061 13.1 0.8 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) SprT-like PF10263.9 AMK77906.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 SprT-like family DUF3021 PF11457.8 AMK77906.1 - 0.4 11.0 11.8 1.8 8.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Phage_holin_3_3 PF16083.5 AMK77906.1 - 4.8 7.4 10.5 2.1 8.5 0.3 3.3 3 1 1 4 4 4 0 LydA holin phage, holin superfamily III DUF2835 PF11197.8 AMK77907.1 - 3.1e-25 87.8 0.3 3.4e-25 87.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2835) Catalase PF00199.19 AMK77908.1 - 0.0057 15.8 0.0 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Catalase DDE_Tnp_1 PF01609.21 AMK77909.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK77909.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK77909.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK77909.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK77909.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK77909.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK77909.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK77909.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK77909.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK77909.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK77909.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK77909.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK77909.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain VHL PF01847.16 AMK77910.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 VHL beta domain AHSA1 PF08327.11 AMK77911.1 - 3.5e-14 53.1 0.0 4e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 AMK77911.1 - 3.3e-09 37.1 0.1 6.3e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_3 PF05977.13 AMK77912.1 - 1.5e-33 116.0 27.5 1.7e-33 115.8 27.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 AMK77912.1 - 1.7e-30 106.1 42.4 1.7e-30 106.1 42.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 AMK77912.1 - 0.31 9.8 14.8 3.8 6.3 14.1 2.3 1 1 0 1 1 1 0 MFS_1 like family UNC-93 PF05978.16 AMK77912.1 - 4.7 6.9 10.6 0.1 12.3 2.2 2.5 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Oxidored_FMN PF00724.20 AMK77913.1 - 1e-62 212.4 0.0 1.2e-62 212.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 AMK77913.1 - 0.0024 17.0 0.0 0.0093 15.1 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Phage_Coat_B PF05356.11 AMK77913.1 - 0.053 13.4 0.2 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Phage Coat protein B Aldedh PF00171.22 AMK77914.1 - 1.3e-29 103.1 7.2 2.9e-19 68.9 4.2 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family RcpC PF16976.5 AMK77914.1 - 0.13 12.3 0.6 0.3 11.1 0.1 1.8 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB CTP_transf_like PF01467.26 AMK77915.1 - 1.4e-28 99.9 0.0 1.6e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like AbiEi_4 PF13338.6 AMK77915.1 - 0.00077 19.6 0.7 0.0025 17.9 0.1 2.2 3 0 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin HIGH_NTase1 PF05636.11 AMK77915.1 - 0.2 10.8 0.1 11 5.1 0.0 2.0 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase RsfS PF02410.15 AMK77916.1 - 5.4e-31 107.0 0.1 6.2e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation LPP20 PF02169.16 AMK77917.1 - 0.0036 17.6 0.0 0.0057 17.0 0.0 1.3 1 0 0 1 1 1 1 LPP20 lipoprotein FlgT_M PF16539.5 AMK77918.1 - 4.1e-29 101.8 0.0 7.2e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Flagellar assembly protein T, middle domain FlgT_C PF16538.5 AMK77918.1 - 7e-07 29.7 0.0 1.9e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Flagellar assembly protein T, C-terminal domain FlgT_N PF16548.5 AMK77918.1 - 0.00079 20.0 1.7 0.0024 18.4 1.7 1.9 1 0 0 1 1 1 1 Flagellar assembly protein T, N-terminal domain GSHPx PF00255.19 AMK77919.1 - 9.5e-47 157.1 0.1 1.2e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AMK77919.1 - 3.8e-07 30.1 0.0 7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK77919.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Redoxin LD_cluster2 PF18163.1 AMK77920.1 - 0.18 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster2 ATF7IP_BD PF16788.5 AMK77920.1 - 1.3 9.0 11.0 4.9 7.2 6.0 2.1 2 0 0 2 2 2 0 ATF-interacting protein binding domain Nucleo_P87 PF07267.11 AMK77920.1 - 3.3 6.5 8.7 3.9 6.2 8.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PEP-CTERM PF07589.11 AMK77921.1 - 1e-06 28.5 0.7 1e-06 28.5 0.7 2.0 2 0 0 2 2 2 1 PEP-CTERM motif Peptidase_S8 PF00082.22 AMK77922.1 - 3.2e-34 118.6 20.0 3.2e-34 118.6 20.0 2.6 2 1 0 2 2 2 1 Subtilase family Big_7 PF17957.1 AMK77922.1 - 5.5e-32 110.4 17.7 7.6e-19 68.3 4.3 5.6 4 2 1 5 5 5 2 Bacterial Ig domain Big_3_3 PF13750.6 AMK77922.1 - 1.7e-06 27.8 5.0 0.0035 17.0 1.1 3.5 3 0 0 3 3 3 2 Bacterial Ig-like domain (group 3) HYR PF02494.16 AMK77922.1 - 0.034 14.5 0.3 12 6.3 0.1 2.8 2 0 0 2 2 2 0 HYR domain Cadherin PF00028.17 AMK77922.1 - 0.32 11.4 1.9 7.3 7.1 0.1 2.9 3 0 0 3 3 3 0 Cadherin domain Peptidase_S8 PF00082.22 AMK77923.1 - 4.4e-40 137.8 17.1 4.4e-40 137.8 17.1 3.1 2 1 0 2 2 2 1 Subtilase family Big_7 PF17957.1 AMK77923.1 - 1.2e-27 96.4 12.6 6.7e-16 58.8 1.6 5.5 4 2 2 6 6 6 2 Bacterial Ig domain Big_3_3 PF13750.6 AMK77923.1 - 0.0003 20.5 8.2 1.1 9.0 0.9 3.9 4 0 0 4 4 4 3 Bacterial Ig-like domain (group 3) HYR PF02494.16 AMK77923.1 - 0.026 14.9 1.2 1.2 9.5 0.1 2.8 2 0 0 2 2 2 0 HYR domain Lipoprotein_21 PF14041.6 AMK77923.1 - 0.026 14.6 0.1 0.073 13.2 0.1 1.8 1 0 0 1 1 1 0 LppP/LprE lipoprotein YpM PF09144.10 AMK77924.1 - 0.067 13.4 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Yersinia pseudo-tuberculosis mitogen HAD_2 PF13419.6 AMK77925.1 - 0.03 14.4 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 AMK77926.1 - 7.9e-25 88.0 0.0 1.2e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 AMK77926.1 - 5.1e-08 33.1 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 TOBE domain RsgA_GTPase PF03193.16 AMK77926.1 - 0.00044 20.2 0.2 0.00087 19.2 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase TOBE_2 PF08402.10 AMK77926.1 - 0.0091 16.1 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 TOBE domain AAA_29 PF13555.6 AMK77926.1 - 0.02 14.6 0.3 0.04 13.7 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AMK77926.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 AMK77926.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AMK77926.1 - 0.15 12.2 0.1 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Virul_Fac PF10139.9 AMK77926.1 - 0.18 10.0 0.1 0.25 9.5 0.1 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor TOBE PF03459.17 AMK77927.1 - 8.4e-39 131.7 7.6 4.6e-19 68.5 0.6 2.0 2 0 0 2 2 2 2 TOBE domain TOBE_2 PF08402.10 AMK77927.1 - 3.3e-06 27.2 1.2 0.023 14.9 0.1 2.1 2 0 0 2 2 2 2 TOBE domain DUF5428 PF17493.2 AMK77927.1 - 0.042 14.3 0.2 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5428) SBP_bac_11 PF13531.6 AMK77928.1 - 3.3e-45 154.6 0.3 3.8e-45 154.4 0.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AMK77928.1 - 6.3e-09 36.2 0.5 0.00066 19.7 0.1 2.0 1 1 1 2 2 2 2 Bacterial extracellular solute-binding protein Alginate_exp PF13372.6 AMK77929.1 - 2e-78 263.9 15.8 2.3e-78 263.7 15.8 1.0 1 0 0 1 1 1 1 Alginate export TOBE PF03459.17 AMK77930.1 - 5.9e-26 90.5 2.8 1.7e-13 50.6 0.1 2.4 2 0 0 2 2 2 2 TOBE domain HTH_1 PF00126.27 AMK77930.1 - 3.2e-11 43.0 0.2 8.2e-11 41.7 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family TOBE_2 PF08402.10 AMK77930.1 - 2.1e-05 24.6 0.5 0.0063 16.7 0.1 2.6 1 1 2 3 3 3 2 TOBE domain Reg_prop PF07494.11 AMK77931.1 - 0.08 13.2 0.1 5.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Two component regulator propeller Rhodanese PF00581.20 AMK77932.1 - 7.5e-17 61.8 0.1 9.7e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DIMCO_N PF16844.5 AMK77933.1 - 3.8e-34 116.9 0.0 6.7e-34 116.1 0.0 1.4 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor, N-terminal Nitro_FeMo-Co PF02579.17 AMK77933.1 - 1.8e-13 50.6 0.0 2.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor DUF2959 PF11172.8 AMK77934.1 - 1.3e-84 283.1 8.4 1.4e-84 283.0 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) DUF3450 PF11932.8 AMK77934.1 - 0.0022 17.4 10.3 0.023 14.0 3.4 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 AMK77934.1 - 0.054 13.5 2.2 0.21 11.6 0.3 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1722 PF08349.11 AMK77934.1 - 0.081 13.2 2.9 0.18 12.1 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) Ferritin PF00210.24 AMK77934.1 - 0.1 12.5 3.1 0.087 12.8 1.3 1.8 2 1 0 2 2 2 0 Ferritin-like domain DUF5595 PF18077.1 AMK77934.1 - 0.2 11.8 4.3 0.1 12.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) SOAR PF16533.5 AMK77934.1 - 0.81 9.7 7.1 0.24 11.4 0.7 2.5 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF1664 PF07889.12 AMK77934.1 - 1.5 8.9 8.8 3.1 7.8 1.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 AMK77934.1 - 2.5 8.6 10.6 15 6.1 7.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 AMK77934.1 - 2.6 8.4 6.5 33 4.8 2.1 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 AMK77934.1 - 4 7.9 11.1 0.92 9.9 0.4 3.3 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ABC_tran_CTD PF16326.5 AMK77934.1 - 9 6.6 9.6 1.6 9.0 0.3 3.4 2 2 2 5 5 5 0 ABC transporter C-terminal domain MgsA_C PF12002.8 AMK77935.1 - 7.5e-70 234.2 0.2 1.1e-69 233.6 0.2 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AMK77935.1 - 2.9e-23 82.0 0.3 8.3e-23 80.5 0.3 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 AMK77935.1 - 4.3e-16 59.5 0.1 1e-15 58.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AMK77935.1 - 2.9e-14 53.1 0.0 5.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 AMK77935.1 - 7e-09 35.4 0.2 0.0019 17.6 0.1 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AMK77935.1 - 1.4e-05 25.5 0.8 0.0024 18.3 0.0 3.1 1 1 2 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 AMK77935.1 - 1.4e-05 25.1 0.2 0.0012 18.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AMK77935.1 - 2.7e-05 24.5 0.1 0.00017 21.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 AMK77935.1 - 0.00012 22.6 0.0 0.00052 20.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AMK77935.1 - 0.00015 21.5 0.0 0.023 14.4 0.0 2.5 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 AMK77935.1 - 0.00017 21.6 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 AMK77935.1 - 0.00052 20.2 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ResIII PF04851.15 AMK77935.1 - 0.00055 20.0 0.1 0.048 13.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 AMK77935.1 - 0.0049 16.6 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AMK77935.1 - 0.0064 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 AMK77935.1 - 0.0067 16.3 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AMK77935.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.6 AMK77935.1 - 0.0077 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AMK77935.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 AMK77935.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 AMK77935.1 - 0.02 14.6 0.2 0.25 11.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 AMK77935.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase AAA_28 PF13521.6 AMK77935.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AMK77935.1 - 0.029 14.7 0.3 4.7 7.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 AMK77935.1 - 0.042 14.4 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 AMK77935.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DNA_pol3_delta2 PF13177.6 AMK77935.1 - 0.13 12.0 0.0 1.1 9.0 0.0 2.1 1 1 0 1 1 1 0 DNA polymerase III, delta subunit ACCA PF03255.14 AMK77936.1 - 5.3e-66 220.9 0.0 1.1e-65 219.9 0.0 1.5 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 AMK77936.1 - 6.9e-21 74.4 0.0 7.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AMK77936.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 1 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) Med9 PF07544.13 AMK77936.1 - 0.052 13.6 0.5 0.052 13.6 0.5 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GlutR_dimer PF00745.20 AMK77936.1 - 0.098 13.1 0.5 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain GAS PF13851.6 AMK77936.1 - 0.19 11.1 3.6 2.4 7.5 0.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 AMK77936.1 - 1.9 8.5 5.4 0.38 10.8 1.4 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATP_bind_3 PF01171.20 AMK77937.1 - 1.5e-50 171.5 0.0 2.3e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 AMK77937.1 - 5.8e-22 76.9 2.8 6.7e-22 76.7 0.2 2.3 2 0 0 2 2 2 1 TilS substrate C-terminal domain TilS PF09179.11 AMK77937.1 - 1.7e-09 38.0 0.0 1.7e-09 38.0 0.0 2.8 3 0 0 3 3 3 1 TilS substrate binding domain PAPS_reduct PF01507.19 AMK77937.1 - 0.0022 18.1 0.0 0.0065 16.5 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 AMK77937.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Arginosuccinate synthase DUF1097 PF06496.11 AMK77938.1 - 0.02 15.0 2.3 0.023 14.8 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) Phage_holin_3_6 PF07332.11 AMK77939.1 - 0.032 14.3 1.6 0.04 13.9 1.6 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MARVEL PF01284.23 AMK77939.1 - 0.039 14.0 1.6 0.047 13.7 1.6 1.0 1 0 0 1 1 1 0 Membrane-associating domain DUF805 PF05656.14 AMK77939.1 - 0.049 14.0 1.9 0.053 13.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF1184 PF06683.11 AMK77939.1 - 0.14 11.7 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) DUF485 PF04341.12 AMK77939.1 - 1.2 9.1 5.9 1.4 8.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 GGDEF PF00990.21 AMK77940.1 - 1.4e-48 164.6 0.5 6.1e-48 162.6 0.2 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PilJ PF13675.6 AMK77940.1 - 4.8e-13 49.1 0.1 1.4e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term PAS_9 PF13426.7 AMK77940.1 - 1.4e-07 31.7 0.1 7.1e-06 26.2 0.2 2.9 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 AMK77940.1 - 2.2e-07 30.9 0.0 5.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK77940.1 - 9.6e-05 22.3 0.0 0.00046 20.1 0.0 2.3 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 AMK77940.1 - 0.0029 17.8 0.0 0.0097 16.1 0.0 1.9 1 1 1 2 2 2 1 PAS fold PAS_4 PF08448.10 AMK77940.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold CTP_synth_N PF06418.14 AMK77941.1 - 5.5e-125 416.0 0.1 7.5e-125 415.6 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AMK77941.1 - 2.4e-59 200.3 0.0 4.1e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AMK77941.1 - 1.1e-06 28.6 0.0 0.017 14.9 0.0 3.1 3 0 0 3 3 3 2 Peptidase C26 CbiA PF01656.23 AMK77941.1 - 0.013 15.5 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNO PF01174.19 AMK77941.1 - 0.11 12.3 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 SNO glutamine amidotransferase family DAHP_synth_1 PF00793.20 AMK77942.1 - 5.1e-71 238.8 0.0 6.1e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Enolase_C PF00113.22 AMK77943.1 - 1.4e-136 454.5 1.8 1.5e-136 454.5 0.7 1.5 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AMK77943.1 - 3.8e-58 195.3 0.4 1e-57 194.0 0.4 1.8 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AMK77943.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AMK77943.1 - 0.024 13.8 0.2 0.049 12.8 0.2 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DivIC PF04977.15 AMK77944.1 - 1.6e-21 75.9 1.1 1.9e-21 75.6 1.1 1.1 1 0 0 1 1 1 1 Septum formation initiator CENP-F_leu_zip PF10473.9 AMK77944.1 - 0.0061 16.6 1.5 0.0065 16.5 1.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 AMK77944.1 - 0.014 15.8 1.0 0.018 15.5 1.0 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 AMK77944.1 - 0.06 14.0 0.3 0.07 13.8 0.3 1.1 1 0 0 1 1 1 0 Initiation control protein YabA IspD PF01128.19 AMK77945.1 - 3e-70 236.4 0.0 3.4e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AMK77945.1 - 2.6e-13 50.6 0.5 4e-13 50.0 0.4 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AMK77945.1 - 5.2e-07 29.8 0.0 8.8e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase NTP_transferase PF00483.23 AMK77945.1 - 0.019 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase YgbB PF02542.16 AMK77946.1 - 9.7e-69 230.6 0.3 1.1e-68 230.4 0.3 1.0 1 0 0 1 1 1 1 YgbB family DUF3005 PF11448.8 AMK77946.1 - 0.034 14.2 0.2 0.39 10.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3005) NPCBM PF08305.11 AMK77946.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 NPCBM/NEW2 domain TruD PF01142.18 AMK77948.1 - 8.7e-70 235.6 0.0 5.5e-42 144.0 0.0 2.0 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) ABC_tran PF00005.27 AMK77949.1 - 6.2e-33 114.2 0.0 1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AMK77949.1 - 3.2e-26 92.6 7.0 4.3e-26 92.2 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AMK77949.1 - 2.6e-05 23.8 0.0 0.00012 21.6 0.0 1.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Peptidase_C39 PF03412.15 AMK77949.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C39 family AAA_21 PF13304.6 AMK77949.1 - 0.011 15.6 0.5 0.4 10.5 0.1 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK77949.1 - 0.092 12.5 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 AMK77949.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HlyD_3 PF13437.6 AMK77950.1 - 2e-19 70.3 1.0 3.2e-16 59.9 0.0 3.0 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK77950.1 - 1.4e-08 34.3 6.4 2.3e-05 23.7 6.4 2.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AMK77950.1 - 3e-06 27.0 1.5 3e-06 27.0 1.5 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.20 AMK77950.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AMK77950.1 - 0.0014 18.4 2.6 0.092 12.6 0.5 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme FtsH_ext PF06480.15 AMK77950.1 - 0.0063 16.9 0.2 0.013 15.9 0.2 1.6 1 0 0 1 1 1 1 FtsH Extracellular SlyX PF04102.12 AMK77950.1 - 1.1 9.9 6.7 19 6.0 0.2 3.2 1 1 2 3 3 3 0 SlyX YtxH PF12732.7 AMK77950.1 - 2.3 8.8 4.4 37 4.9 0.2 2.6 2 0 0 2 2 2 0 YtxH-like protein GerE PF00196.19 AMK77951.1 - 3.3e-19 68.2 0.4 6.3e-19 67.3 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AMK77951.1 - 8.4e-06 25.4 1.5 2.4e-05 23.9 0.2 2.4 2 1 1 3 3 3 1 Sigma-70, region 4 HTH_38 PF13936.6 AMK77951.1 - 0.00062 19.5 2.5 1 9.2 0.1 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 AMK77951.1 - 0.0047 16.8 0.1 0.0071 16.3 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor DUF2089 PF09862.9 AMK77951.1 - 0.011 15.8 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_23 PF13384.6 AMK77951.1 - 0.013 15.3 0.8 0.11 12.3 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_40 PF14493.6 AMK77951.1 - 0.016 15.6 0.4 0.044 14.3 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AMK77951.1 - 0.025 14.1 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3071 PF11268.8 AMK77951.1 - 0.068 13.2 0.2 0.16 12.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3071) HTH_10 PF04967.12 AMK77951.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 HTH DNA binding domain HTH_29 PF13551.6 AMK77951.1 - 0.13 12.3 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 AMK77951.1 - 0.18 11.9 0.7 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase OEP PF02321.18 AMK77952.1 - 4.6e-46 157.0 7.1 6.4e-29 101.1 0.9 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein FdsD PF11390.8 AMK77953.1 - 9.2e-28 96.4 0.0 1.1e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 NADH-dependant formate dehydrogenase delta subunit FdsD GPW_gp25 PF04965.14 AMK77953.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Gene 25-like lysozyme Integrase_H2C2 PF17921.1 AMK77953.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Integrase zinc binding domain FdhD-NarQ PF02634.15 AMK77954.1 - 3.5e-73 246.2 0.2 4.1e-73 246.0 0.2 1.0 1 0 0 1 1 1 1 FdhD/NarQ family Molybdopterin PF00384.22 AMK77955.1 - 5.6e-74 249.6 0.0 7.2e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AMK77955.1 - 8e-28 96.7 0.1 1.7e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer2_4 PF13510.6 AMK77955.1 - 2.7e-24 85.0 0.9 7.6e-24 83.6 0.9 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 AMK77955.1 - 2e-15 56.0 0.2 2e-15 56.0 0.2 3.1 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molybdop_Fe4S4 PF04879.16 AMK77955.1 - 3.6e-15 55.7 1.2 1.1e-14 54.1 1.2 1.9 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4_21 PF14697.6 AMK77955.1 - 3.9e-08 33.3 6.0 3.9e-08 33.3 6.0 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 AMK77955.1 - 1.9e-07 30.9 0.1 1.9e-07 30.9 0.1 2.2 2 0 0 2 2 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AMK77955.1 - 7.7e-07 28.7 19.6 1.3e-05 24.8 1.9 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AMK77955.1 - 5.9e-06 26.4 9.1 5.9e-06 26.4 9.1 3.9 3 1 2 5 5 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK77955.1 - 5.7e-05 23.6 11.9 5.7e-05 23.6 11.9 4.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK77955.1 - 8e-05 22.5 10.8 0.00026 20.9 1.8 4.0 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 AMK77955.1 - 0.00025 21.4 6.4 0.00025 21.4 6.4 3.4 5 1 0 5 5 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK77955.1 - 0.0028 17.7 14.0 0.0028 17.7 14.0 3.6 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK77955.1 - 0.003 17.5 3.8 0.003 17.5 3.8 3.9 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AMK77955.1 - 0.0052 17.7 2.1 0.0052 17.7 2.1 3.7 3 1 1 4 4 3 1 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AMK77955.1 - 0.027 15.2 8.9 1.3 9.8 0.3 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AMK77955.1 - 0.052 13.8 14.2 0.77 10.0 4.7 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AMK77955.1 - 0.74 10.4 13.0 0.75 10.4 2.7 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AMK77955.1 - 1.1 10.1 14.3 9.9 7.1 0.3 3.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Complex1_51K PF01512.17 AMK77956.1 - 6.2e-44 149.5 0.0 9.2e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AMK77956.1 - 2.3e-30 104.5 0.2 4.4e-30 103.6 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AMK77956.1 - 2.8e-08 33.5 0.1 7.3e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 SLBB domain 2Fe-2S_thioredx PF01257.19 AMK77957.1 - 2.8e-43 147.3 0.0 3.3e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Rotamase_3 PF13616.6 AMK77958.1 - 6.4e-21 75.1 0.0 1.8e-20 73.6 0.0 1.8 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 AMK77958.1 - 1.7e-17 64.1 0.0 1.7e-17 64.1 0.0 3.1 3 1 0 4 4 4 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 AMK77958.1 - 3.1e-17 63.5 0.0 3.1e-17 63.5 0.0 2.5 3 0 0 3 3 3 1 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AMK77958.1 - 7.2e-06 25.9 4.2 7.2e-06 25.9 4.2 2.0 2 1 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 AMK77958.1 - 0.0013 18.6 3.6 0.0024 17.8 2.2 2.2 2 1 0 2 2 2 1 SurA N-terminal domain PDZ_2 PF13180.6 AMK77958.1 - 0.0073 16.6 0.0 0.027 14.8 0.0 1.9 1 0 0 1 1 1 1 PDZ domain SMC_hinge PF06470.13 AMK77958.1 - 0.063 13.6 0.1 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain DUF416 PF04222.12 AMK77958.1 - 0.081 12.3 3.6 0.15 11.5 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF416) Med26_C PF15693.5 AMK77958.1 - 9.2 6.4 7.1 6.1 6.9 0.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal BolA PF01722.18 AMK77959.1 - 2.3e-29 101.5 0.1 2.6e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 BolA-like protein YCII PF03795.14 AMK77960.1 - 3.6e-26 91.4 0.0 4e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF1330 PF07045.11 AMK77960.1 - 0.15 12.4 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1330) IspA PF04279.15 AMK77961.1 - 2.9e-67 226.3 17.8 3.2e-67 226.1 17.8 1.0 1 0 0 1 1 1 1 Intracellular septation protein A MerC PF03203.14 AMK77961.1 - 0.077 13.5 8.6 0.074 13.5 5.5 2.1 1 1 1 2 2 2 0 MerC mercury resistance protein DUF2976 PF11190.8 AMK77961.1 - 1 9.2 12.9 0.56 10.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Stevor PF17410.2 AMK77961.1 - 3.6 7.1 7.8 3.8 7.0 0.1 2.1 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame MG4 PF17789.1 AMK77962.1 - 0.032 14.4 1.0 0.047 13.8 0.8 1.3 1 1 0 1 1 1 0 Macroglobulin domain MG4 Pol_alpha_B_N PF08418.10 AMK77962.1 - 0.059 13.3 3.3 0.069 13.1 3.3 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1244 PF06844.11 AMK77963.1 - 2.7e-37 126.7 0.8 3.8e-37 126.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1244) DAO PF01266.24 AMK77963.1 - 0.17 11.4 0.4 0.28 10.7 0.4 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.6 AMK77964.1 - 1.2e-15 58.0 0.0 2.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK77964.1 - 2.1e-15 57.2 0.0 5e-15 55.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK77964.1 - 2.6e-11 44.1 0.0 4.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK77964.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AMK77964.1 - 2.3e-10 40.4 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK77964.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 AMK77964.1 - 0.00013 22.9 0.0 0.00031 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 AMK77964.1 - 0.00015 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 AMK77964.1 - 0.0029 17.4 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 AMK77964.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AMK77964.1 - 0.026 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 AMK77964.1 - 0.034 14.2 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 AMK77964.1 - 0.12 11.6 0.0 0.49 9.5 0.0 1.9 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family CheR PF01739.18 AMK77964.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain SPOR PF05036.13 AMK77965.1 - 1e-07 32.2 0.7 5.9e-07 29.8 0.7 2.4 1 0 0 1 1 1 1 Sporulation related domain SOGA PF11365.8 AMK77965.1 - 0.029 15.5 0.9 10 7.3 0.2 2.6 2 0 0 2 2 2 0 Protein SOGA Nsp1_C PF05064.13 AMK77965.1 - 0.1 12.4 6.9 0.035 13.9 1.4 3.0 2 1 1 3 3 3 0 Nsp1-like C-terminal region HBM PF16591.5 AMK77965.1 - 0.55 9.6 6.3 0.1 12.0 0.7 2.5 3 0 0 3 3 3 0 Helical bimodular sensor domain Spc7 PF08317.11 AMK77965.1 - 3 6.6 9.4 6.9 5.5 4.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein 5-nucleotidase PF06189.12 AMK77966.1 - 1.5e-113 378.1 0.0 3.6e-113 376.9 0.0 1.5 2 0 0 2 2 2 1 5'-nucleotidase DUF5338 PF17273.2 AMK77966.1 - 0.16 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Acid_PPase PF12689.7 AMK77966.1 - 0.21 11.4 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase CN_hydrolase PF00795.22 AMK77968.1 - 9.1e-27 94.0 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NADH-u_ox-rdase PF10785.9 AMK77968.1 - 0.053 14.2 0.9 0.053 14.2 0.9 2.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit TruB_C PF09142.11 AMK77968.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Alk_phosphatase PF00245.20 AMK77969.1 - 2.8e-126 421.8 2.2 3.2e-126 421.6 2.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 AMK77969.1 - 4.9e-06 26.1 0.2 2.6e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 AMK77969.1 - 0.0001 21.8 1.0 0.00025 20.6 1.0 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AMK77969.1 - 0.038 13.6 0.2 0.077 12.6 0.2 1.6 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase HDOD PF08668.12 AMK77970.1 - 2.1e-30 105.7 0.0 2.5e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 HDOD domain HDOD PF08668.12 AMK77971.1 - 4.2e-08 32.9 0.0 5.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK77971.1 - 0.028 14.6 0.1 0.054 13.7 0.1 1.7 1 1 0 1 1 1 0 HD domain Acetyltransf_1 PF00583.25 AMK77972.1 - 5.3e-19 68.6 0.0 8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AMK77972.1 - 1.4e-14 54.1 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AMK77972.1 - 4.1e-13 49.6 0.0 7.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AMK77972.1 - 9.2e-09 36.1 0.0 1.1e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AMK77972.1 - 2.2e-08 34.0 0.0 3.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 AMK77972.1 - 1.9e-07 31.3 0.0 2.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AMK77972.1 - 0.00034 20.3 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK77972.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AMK77972.1 - 0.0023 18.1 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AMK77972.1 - 0.0034 17.4 0.0 0.008 16.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AMK77972.1 - 0.051 13.1 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase GNAT_acetyltr_2 PF13718.6 AMK77972.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 UDG PF03167.19 AMK77973.1 - 7.9e-45 152.6 0.1 1.6e-44 151.6 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DNA_III_psi PF03603.13 AMK77973.1 - 0.00029 21.1 0.4 0.21 11.8 0.0 2.8 3 1 0 3 3 3 2 DNA polymerase III psi subunit HMGL-like PF00682.19 AMK77974.1 - 4.1e-101 338.0 1.0 6.4e-101 337.3 1.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AMK77974.1 - 2.5e-36 124.5 3.3 5.4e-36 123.4 3.3 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Profilin PF00235.19 AMK77974.1 - 0.084 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Profilin CHAD PF05235.14 AMK77975.1 - 7e-26 91.6 3.1 9.5e-26 91.2 3.1 1.1 1 0 0 1 1 1 1 CHAD domain Ldi PF18566.1 AMK77975.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Perilipin PF03036.16 AMK77975.1 - 0.0083 15.2 0.1 0.013 14.6 0.1 1.3 1 1 0 1 1 1 1 Perilipin family CDP-OH_P_transf PF01066.21 AMK77976.1 - 2.7e-12 47.3 4.4 3.9e-12 46.8 0.6 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CclA_1 PF16942.5 AMK77976.1 - 0.11 12.8 4.0 0.21 11.9 0.4 2.8 2 1 1 3 3 3 0 Putative cyclic bacteriocin DUF5020 PF16412.5 AMK77977.1 - 6.7e-11 42.4 1.0 4e-10 39.9 1.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5020) Channel_Tsx PF03502.13 AMK77977.1 - 3e-10 40.3 3.1 4.1e-10 39.8 3.1 1.2 1 0 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx IlvN PF07991.12 AMK77978.1 - 1.2e-73 246.1 2.7 1.6e-73 245.7 2.7 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AMK77978.1 - 3.9e-63 212.0 0.1 5.5e-63 211.6 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 AMK77978.1 - 3.6e-07 30.7 0.3 7.2e-07 29.7 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AMK77978.1 - 4e-07 29.6 0.1 6.7e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AMK77978.1 - 5.2e-05 23.5 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 AMK77978.1 - 0.00017 22.0 0.1 0.0005 20.5 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding CoA_binding PF02629.19 AMK77978.1 - 0.00023 21.8 0.5 0.0006 20.4 0.5 1.7 1 0 0 1 1 1 1 CoA binding domain AdoHcyase_NAD PF00670.21 AMK77978.1 - 0.00032 20.8 0.1 0.00059 19.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 AMK77978.1 - 0.0013 18.4 0.2 0.0029 17.3 0.2 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Mur_ligase PF01225.25 AMK77978.1 - 0.0013 19.0 0.9 0.0042 17.4 0.3 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain NAD_Gly3P_dh_N PF01210.23 AMK77978.1 - 0.01 15.8 0.3 0.9 9.5 0.3 2.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AMK77978.1 - 0.012 16.4 0.1 0.026 15.4 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Oxidored_nitro PF00148.19 AMK77978.1 - 0.015 14.0 0.1 0.048 12.4 0.0 1.8 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Shikimate_DH PF01488.20 AMK77978.1 - 0.016 15.3 0.1 0.035 14.2 0.1 1.6 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 AMK77978.1 - 0.018 14.9 0.3 0.033 14.0 0.3 1.4 1 0 0 1 1 1 0 Rossmann-like domain ALS_ss_C PF10369.9 AMK77979.1 - 1.9e-27 95.3 2.8 4e-27 94.2 0.3 2.2 2 1 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 AMK77979.1 - 6.8e-17 61.1 0.0 2.1e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 AMK77979.1 - 1e-14 53.9 0.1 2.2e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AMK77979.1 - 0.024 15.2 0.0 0.055 14.1 0.0 1.6 1 1 0 1 1 1 0 ACT domain SCO1-SenC PF02630.14 AMK77979.1 - 0.18 11.7 0.1 0.36 10.8 0.0 1.5 1 1 0 1 1 1 0 SCO1/SenC TPP_enzyme_N PF02776.18 AMK77980.1 - 1.2e-58 197.6 0.2 8.5e-58 194.7 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AMK77980.1 - 4e-50 169.6 0.4 1.1e-47 161.6 0.0 3.0 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AMK77980.1 - 5.1e-46 155.8 0.0 8.8e-46 155.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 AMK77980.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ACPS PF01648.20 AMK77981.1 - 3.7e-18 65.7 0.0 6.4e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Response_reg PF00072.24 AMK77983.1 - 3.5e-28 98.0 0.0 5.6e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK77983.1 - 1.6e-12 46.8 0.0 5.2e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AMK77983.1 - 0.01 15.6 0.0 0.033 14.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 AMK77983.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 AMK77983.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 AMK77983.1 - 0.036 13.6 0.2 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.12 AMK77983.1 - 0.044 13.7 0.1 0.23 11.4 0.0 2.2 2 1 0 2 2 2 0 HTH domain HTH_38 PF13936.6 AMK77983.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HisKA_3 PF07730.13 AMK77984.1 - 8.3e-11 42.3 0.9 8.3e-11 42.3 0.9 3.3 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 AMK77984.1 - 0.00053 20.5 0.0 0.0027 18.2 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Polyketide_cyc2 PF10604.9 AMK77985.1 - 4.9e-20 72.3 0.8 6.3e-20 71.9 0.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AMK77985.1 - 0.003 17.8 0.0 0.0037 17.5 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3280 PF11684.8 AMK77986.1 - 2.5e-22 79.8 0.0 3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) Ribosomal_S9 PF00380.19 AMK77987.1 - 2.9e-43 147.2 0.1 3.3e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 AMK77988.1 - 8.3e-57 190.9 0.1 9.4e-57 190.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3659 PF12396.8 AMK77988.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Sigma54_activat PF00158.26 AMK77989.1 - 1.4e-42 145.3 0.1 2.4e-42 144.5 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK77989.1 - 7.5e-28 96.9 0.1 1.4e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AMK77989.1 - 5e-24 85.0 0.0 1.1e-23 83.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK77989.1 - 0.0001 22.0 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AMK77989.1 - 0.00092 18.6 0.1 3.1 7.1 0.0 3.1 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AMK77989.1 - 0.0019 18.2 0.0 0.066 13.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AMK77989.1 - 0.014 14.9 0.0 0.046 13.2 0.0 1.8 1 1 1 2 2 2 0 P-loop containing dynein motor region FleQ PF06490.11 AMK77989.1 - 0.017 15.5 0.1 0.041 14.3 0.1 1.7 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ AAA_16 PF13191.6 AMK77989.1 - 0.022 15.2 0.7 0.15 12.4 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain MCM PF00493.23 AMK77989.1 - 0.025 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 AMK77989.1 - 0.028 14.3 0.3 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase HTH_Crp_2 PF13545.6 AMK77989.1 - 0.052 13.5 0.2 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain AAA PF00004.29 AMK77989.1 - 0.07 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 AMK77989.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 AMK77989.1 - 0.12 12.6 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HATPase_c PF02518.26 AMK77990.1 - 1.5e-20 73.7 0.0 3e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AMK77990.1 - 1.5e-12 47.7 0.4 8.5e-12 45.3 0.0 2.6 3 0 0 3 3 2 1 HAMP domain HisKA PF00512.25 AMK77990.1 - 1.2e-09 38.1 1.9 1.3e-08 34.8 0.0 3.6 4 1 0 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AMK77990.1 - 5.1e-08 33.2 0.0 1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AMK77990.1 - 4.7e-06 26.6 0.0 1.9e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AMK77990.1 - 2.9e-05 24.2 0.0 0.00015 22.0 0.0 2.2 1 1 1 2 2 2 1 PAS domain PAS_7 PF12860.7 AMK77990.1 - 3.5e-05 24.0 0.0 0.00022 21.4 0.0 2.4 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 AMK77990.1 - 0.00035 20.4 0.0 0.00093 19.1 0.0 1.7 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 AMK77990.1 - 0.00066 19.6 0.0 0.0023 17.9 0.0 2.0 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AMK77990.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tetraspanin PF00335.20 AMK77990.1 - 0.0014 18.3 2.5 0.15 11.8 0.9 2.2 2 0 0 2 2 2 2 Tetraspanin family DUF4199 PF13858.6 AMK77990.1 - 0.013 16.0 1.6 0.013 16.0 1.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) HATPase_c_2 PF13581.6 AMK77990.1 - 0.013 15.4 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CopD PF05425.13 AMK77990.1 - 0.017 15.5 2.6 0.017 15.5 2.6 2.2 2 0 0 2 2 2 0 Copper resistance protein D Yip1 PF04893.17 AMK77990.1 - 0.084 12.6 4.9 0.26 11.0 0.9 2.3 2 0 0 2 2 2 0 Yip1 domain PHO4 PF01384.20 AMK77990.1 - 0.084 11.9 1.1 0.13 11.3 0.8 1.4 1 1 0 1 1 1 0 Phosphate transporter family FAM92 PF06730.11 AMK77990.1 - 0.095 12.1 0.0 0.3 10.5 0.0 1.8 1 0 0 1 1 1 0 FAM92 protein AA_permease PF00324.21 AMK77990.1 - 3.3 6.2 11.3 0.031 12.9 3.5 1.4 2 0 0 2 2 2 0 Amino acid permease DUF4390 PF14334.6 AMK77991.1 - 1.4e-35 122.1 0.2 1.7e-35 121.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4390) Methyltr_RsmB-F PF01189.17 AMK77992.1 - 1.9e-61 207.2 0.0 2.8e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 AMK77992.1 - 9.3e-22 77.7 0.0 1.8e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 NusB family FtsJ PF01728.19 AMK77992.1 - 1.2e-08 35.3 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 AMK77992.1 - 8.4e-08 32.1 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 AMK77992.1 - 7.2e-07 29.6 0.0 2.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF MTS PF05175.14 AMK77992.1 - 5.5e-05 22.8 0.1 0.0013 18.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AMK77992.1 - 7.6e-05 23.3 0.0 0.0022 18.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 AMK77992.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_11 PF08241.12 AMK77992.1 - 0.026 15.2 0.0 0.44 11.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain DUF4089 PF13318.6 AMK77992.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) POR PF01558.18 AMK77992.1 - 0.12 12.4 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Methyltransf_23 PF13489.6 AMK77992.1 - 0.16 11.8 0.0 0.59 10.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Formyl_trans_N PF00551.19 AMK77993.1 - 4.6e-45 153.6 0.0 7.7e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AMK77993.1 - 1e-24 86.6 0.0 2.2e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Pep_deformylase PF01327.21 AMK77994.1 - 3.6e-51 172.9 0.1 4.2e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 Polypeptide deformylase LysM PF01476.20 AMK77995.1 - 2.9e-13 49.6 0.0 5.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain FlgT_C PF16538.5 AMK77995.1 - 0.061 13.8 0.0 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain DNA_processg_A PF02481.15 AMK77996.1 - 2.5e-79 265.4 0.0 3.2e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AMK77996.1 - 3.6e-16 59.0 0.9 1.2e-15 57.4 0.4 2.2 2 0 0 2 2 2 1 DprA winged helix domain HTH_15 PF12324.8 AMK77996.1 - 0.022 14.7 0.0 0.087 12.8 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase LDcluster4 PF18306.1 AMK77996.1 - 0.07 12.7 0.9 0.31 10.6 0.9 1.9 1 1 0 1 1 1 0 SLOG cluster4 family Keratin PF02422.16 AMK77996.1 - 0.11 12.2 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Keratin DUF494 PF04361.13 AMK77997.1 - 3.8e-49 166.5 0.0 4.1e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF494) Topoisom_bac PF01131.20 AMK77998.1 - 1.6e-129 432.5 0.3 2.1e-129 432.2 0.3 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-C4_Topoisom PF01396.19 AMK77998.1 - 1.4e-41 139.9 27.9 5.6e-15 54.8 3.5 4.5 4 0 0 4 4 4 3 Topoisomerase DNA binding C4 zinc finger Toprim PF01751.22 AMK77998.1 - 6.5e-26 90.6 0.1 1.3e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 Toprim domain Auto_anti-p27 PF06677.12 AMK77998.1 - 0.0079 16.3 12.0 1.6 9.0 0.4 4.4 4 0 0 4 4 4 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Toprim_4 PF13662.6 AMK77998.1 - 0.027 14.9 0.1 0.11 13.0 0.1 2.1 1 1 0 1 1 1 0 Toprim domain A2L_zn_ribbon PF08792.10 AMK77998.1 - 0.17 11.6 4.1 12 5.8 0.1 3.8 3 0 0 3 3 3 0 A2L zinc ribbon domain RNA_POL_M_15KD PF02150.16 AMK77998.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.7 3 2 2 5 5 5 0 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 AMK77998.1 - 0.24 10.9 13.3 7.1 6.2 0.2 5.0 5 0 0 5 5 5 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 AMK77998.1 - 0.83 9.7 13.3 1e+02 3.0 0.2 4.3 2 1 2 4 4 4 0 zinc-ribbons Zn-ribbon_8 PF09723.10 AMK77998.1 - 1.1 9.4 16.6 2.7 8.2 0.1 4.8 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.13 AMK77998.1 - 1.3 8.9 9.2 3.3 7.5 0.0 4.1 4 0 0 4 4 4 0 InsA N-terminal domain zf-Mss51 PF13824.6 AMK77998.1 - 7.2 6.8 11.5 8.4 6.6 0.0 3.5 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF192 PF02643.15 AMK77999.1 - 2e-30 104.8 0.0 3.8e-30 103.9 0.0 1.4 1 1 1 2 2 2 1 Uncharacterized ACR, COG1430 Trigger_N PF05697.13 AMK78000.1 - 6.5e-39 133.5 3.5 6.5e-39 133.5 3.5 2.9 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 AMK78000.1 - 4.5e-36 124.3 12.2 6.1e-32 110.9 5.0 3.1 2 1 1 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 AMK78000.1 - 5.4e-13 49.1 0.4 1.4e-12 47.8 0.4 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3562 PF12085.8 AMK78000.1 - 0.074 12.7 0.6 4.3 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3562) PG_binding_4 PF12229.8 AMK78000.1 - 0.5 10.7 3.8 1.2 9.5 0.2 3.1 3 1 0 3 3 3 0 Putative peptidoglycan binding domain Spore_II_R PF09551.10 AMK78000.1 - 1.8 9.0 4.9 0.79 10.2 0.1 2.7 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) CLP_protease PF00574.23 AMK78001.1 - 3.9e-87 290.9 0.0 4.6e-87 290.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 AMK78001.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 AAA_2 PF07724.14 AMK78002.1 - 1.5e-46 158.7 0.0 2.4e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 AMK78002.1 - 3e-20 71.8 3.5 6.9e-20 70.7 3.5 1.7 1 0 0 1 1 1 1 ClpX C4-type zinc finger ClpB_D2-small PF10431.9 AMK78002.1 - 1.7e-16 60.0 2.5 4.8e-16 58.6 0.4 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AMK78002.1 - 1.2e-15 58.1 0.2 1.1e-14 55.0 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK78002.1 - 4.5e-07 29.9 0.1 1.6e-05 24.9 0.1 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AMK78002.1 - 1.3e-05 24.7 0.4 0.00092 18.7 0.5 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AMK78002.1 - 1.8e-05 25.0 0.1 0.00024 21.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 AMK78002.1 - 2.6e-05 24.0 0.1 7.3e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 AMK78002.1 - 8.2e-05 21.8 0.1 0.00016 20.9 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 AMK78002.1 - 0.00014 21.6 0.0 0.047 13.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 AMK78002.1 - 0.00051 20.5 0.0 0.0017 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 AMK78002.1 - 0.00093 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TIP49 PF06068.13 AMK78002.1 - 0.0011 18.2 0.1 0.0033 16.7 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 AMK78002.1 - 0.0025 17.4 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 AMK78002.1 - 0.0029 17.7 0.0 0.0079 16.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 AMK78002.1 - 0.0039 17.7 0.2 0.021 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AMK78002.1 - 0.005 16.6 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 AMK78002.1 - 0.0065 16.5 0.2 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 AMK78002.1 - 0.0086 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 AMK78002.1 - 0.012 16.1 0.0 0.033 14.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 AMK78002.1 - 0.018 14.7 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AMK78002.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 AMK78002.1 - 0.023 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AMK78002.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 AMK78002.1 - 0.034 14.1 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 AMK78002.1 - 0.044 14.1 0.1 2.1 8.7 0.0 3.0 3 1 1 4 4 4 0 AAA domain AAA_15 PF13175.6 AMK78002.1 - 0.06 13.1 0.1 0.37 10.5 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF1296 PF06972.11 AMK78002.1 - 0.06 13.5 0.8 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) AAA_PrkA PF08298.11 AMK78002.1 - 0.065 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain SMC_N PF02463.19 AMK78002.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ResIII PF04851.15 AMK78002.1 - 0.077 13.0 0.1 0.24 11.4 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 AMK78002.1 - 0.085 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 AMK78002.1 - 0.18 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 AMK78002.1 - 0.19 11.5 0.7 0.83 9.4 0.0 2.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase ATPase PF06745.13 AMK78002.1 - 1.6 8.1 4.4 3.3 7.0 1.0 2.5 2 1 0 2 2 2 0 KaiC Lon_C PF05362.13 AMK78003.1 - 1.4e-96 321.9 2.0 2.8e-96 321.0 2.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 AMK78003.1 - 6.6e-40 137.2 0.9 6.6e-40 137.2 0.9 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 AMK78003.1 - 3.9e-21 75.9 0.1 6.6e-19 68.6 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK78003.1 - 2.4e-10 40.6 0.0 8.2e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 AMK78003.1 - 8.9e-08 32.0 0.1 2.8e-07 30.4 0.1 2.0 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 AMK78003.1 - 5.2e-05 22.3 0.1 0.00015 20.8 0.0 1.7 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 AMK78003.1 - 7.2e-05 23.2 0.0 0.00027 21.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 AMK78003.1 - 0.0026 17.5 0.0 0.0095 15.7 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 AMK78003.1 - 0.0029 17.4 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AMK78003.1 - 0.004 17.4 0.1 0.05 13.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AMK78003.1 - 0.0048 16.9 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 AMK78003.1 - 0.007 16.9 0.2 0.033 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AMK78003.1 - 0.011 15.6 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 AMK78003.1 - 0.012 15.5 0.0 0.082 12.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AMK78003.1 - 0.014 15.3 0.0 0.047 13.6 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 AMK78003.1 - 0.091 13.3 2.3 0.46 11.0 0.0 2.7 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 AMK78003.1 - 0.12 12.7 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 AMK78003.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AMK78003.1 - 0.15 12.2 0.2 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pyr_redox PF00070.27 AMK78003.1 - 0.15 12.6 3.2 0.28 11.8 1.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase T3SSipB PF16535.5 AMK78003.1 - 0.93 10.0 7.6 1.4 9.4 4.9 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB EF1_GNE PF00736.19 AMK78003.1 - 1.8 8.8 6.2 2.1 8.6 0.1 3.1 2 1 0 2 2 2 0 EF-1 guanine nucleotide exchange domain AAA_23 PF13476.6 AMK78003.1 - 1.9 8.9 9.3 28 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain Bac_DNA_binding PF00216.21 AMK78004.1 - 7.1e-36 122.3 0.2 7.8e-36 122.2 0.2 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AMK78004.1 - 1.2e-10 41.5 0.0 1.3e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AMK78004.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AMK78004.1 - 0.00065 19.8 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AMK78004.1 - 0.00092 19.3 0.0 0.001 19.2 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Phage_holin_2_4 PF16082.5 AMK78004.1 - 0.037 13.8 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SurA_N_3 PF13624.6 AMK78005.1 - 9e-40 136.1 3.6 9e-40 136.1 3.6 3.5 3 0 0 3 3 3 2 SurA N-terminal domain Rotamase_2 PF13145.6 AMK78005.1 - 1.6e-26 93.5 46.0 2.8e-21 76.6 5.2 5.1 3 2 2 5 5 5 4 PPIC-type PPIASE domain Rotamase PF00639.21 AMK78005.1 - 4.8e-25 88.4 16.5 2.3e-23 83.0 0.2 4.6 4 1 0 4 4 4 2 PPIC-type PPIASE domain SurA_N_2 PF13623.6 AMK78005.1 - 7.9e-25 87.4 1.0 4.3e-24 85.0 1.0 2.4 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_3 PF13616.6 AMK78005.1 - 2.3e-24 86.1 1.2 2.3e-24 86.1 1.2 3.9 4 0 0 4 4 4 1 PPIC-type PPIASE domain SurA_N PF09312.11 AMK78005.1 - 3.1e-07 30.5 0.9 3.1e-07 30.5 0.9 3.5 3 0 0 3 3 3 1 SurA N-terminal domain Enoyl_reductase PF12241.8 AMK78007.1 - 1.3e-109 365.0 0.2 1.7e-109 364.7 0.2 1.1 1 0 0 1 1 1 1 Trans-2-enoyl-CoA reductase catalytic region Eno-Rase_NADH_b PF12242.8 AMK78007.1 - 7.3e-37 125.0 0.1 1.5e-36 124.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Eno-Rase_FAD_bd PF07055.12 AMK78007.1 - 4.6e-28 97.4 1.0 1e-27 96.3 1.0 1.6 1 0 0 1 1 1 1 Enoyl reductase FAD binding domain SBP_bac_5 PF00496.22 AMK78008.1 - 1.1e-76 258.2 4.8 1.7e-76 257.6 4.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 AMK78009.1 - 2.3e-30 105.7 5.4 2.3e-30 105.7 5.4 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DPM2 PF07297.12 AMK78009.1 - 1.2 9.5 7.4 1.8 8.9 0.0 3.5 3 0 0 3 3 3 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BPD_transp_1 PF00528.22 AMK78010.1 - 6.6e-21 74.9 10.6 6.6e-21 74.9 10.6 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AMK78010.1 - 0.00045 20.1 1.6 0.00045 20.1 1.6 3.3 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C VSP PF03302.13 AMK78010.1 - 1.7 7.4 2.4 2.4 6.9 2.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein ABC_tran PF00005.27 AMK78011.1 - 1e-59 201.0 0.0 1.1e-29 103.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 AMK78011.1 - 1e-14 54.7 0.1 1.1e-06 29.0 0.1 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AMK78011.1 - 2.1e-13 50.3 0.0 2.4e-05 23.9 0.2 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK78011.1 - 7.1e-12 45.7 3.1 0.00014 21.8 0.1 4.0 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 AMK78011.1 - 2.9e-11 43.8 4.6 6.8e-06 26.4 0.4 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AMK78011.1 - 1e-07 32.5 3.7 2.8e-05 24.6 0.3 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 AMK78011.1 - 4.9e-06 27.0 0.0 0.0053 17.2 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AMK78011.1 - 1.1e-05 25.0 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATPase PF06745.13 AMK78011.1 - 1.9e-05 24.2 0.6 0.026 13.9 0.0 3.0 3 0 0 3 3 3 2 KaiC AAA_5 PF07728.14 AMK78011.1 - 6.7e-05 22.9 1.0 1.6 8.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 AMK78011.1 - 0.00014 21.5 5.2 0.14 11.7 0.4 3.7 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 AMK78011.1 - 0.00026 20.9 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 AMK78011.1 - 0.00052 19.6 0.0 0.98 8.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 AMK78011.1 - 0.00058 19.8 0.1 0.49 10.3 0.1 2.5 2 0 0 2 2 2 2 NACHT domain Mg_chelatase PF01078.21 AMK78011.1 - 0.001 18.5 0.0 1.3 8.4 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AMK78011.1 - 0.0015 18.3 0.1 3.7 7.2 0.0 3.6 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_23 PF13476.6 AMK78011.1 - 0.0021 18.6 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AMK78011.1 - 0.0026 17.9 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 AMK78011.1 - 0.0075 15.5 0.0 0.089 12.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain ATP-synt_ab PF00006.25 AMK78011.1 - 0.0084 15.8 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain TniB PF05621.11 AMK78011.1 - 0.0092 15.4 0.2 3.2 7.1 0.0 3.5 4 0 0 4 4 4 1 Bacterial TniB protein TsaE PF02367.17 AMK78011.1 - 0.011 15.7 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AMK78011.1 - 0.013 15.2 0.1 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AMK78011.1 - 0.015 15.1 0.0 8.4 6.1 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 AMK78011.1 - 0.038 14.4 0.1 10 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 AMK78011.1 - 0.082 12.6 0.0 17 5.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 AMK78011.1 - 0.085 12.1 0.1 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 AMK78011.1 - 0.14 11.9 0.7 0.45 10.3 0.0 2.2 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation OAM_alpha PF16552.5 AMK78014.1 - 0.014 15.3 0.1 26 4.7 0.0 3.1 3 0 0 3 3 3 0 D-ornithine 4,5-aminomutase alpha-subunit RHH_4 PF13467.6 AMK78014.1 - 0.035 14.0 0.1 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Ribbon-helix-helix domain Sigma54_activat PF00158.26 AMK78015.1 - 9.5e-63 210.9 0.1 1.7e-62 210.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK78015.1 - 8.2e-21 74.6 0.0 4.3e-20 72.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK78015.1 - 1.6e-15 57.2 0.0 4.3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 AMK78015.1 - 1.9e-10 40.4 0.3 4.6e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AMK78015.1 - 3.8e-08 33.0 0.3 6.6e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AMK78015.1 - 1.2e-06 28.9 0.0 3.3e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AMK78015.1 - 0.0016 18.2 0.8 0.0041 16.9 0.8 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_16 PF13191.6 AMK78015.1 - 0.002 18.5 0.3 0.0083 16.5 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 AMK78015.1 - 0.0027 17.7 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) HTH_28 PF13518.6 AMK78015.1 - 0.0034 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_22 PF13401.6 AMK78015.1 - 0.0051 17.1 0.5 0.2 11.9 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 AMK78015.1 - 0.0051 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 AMK78015.1 - 0.0057 16.4 0.1 0.038 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 AMK78015.1 - 0.098 11.7 0.2 0.69 9.0 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain HATPase_c PF02518.26 AMK78016.1 - 1.6e-13 51.1 0.1 5.2e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78016.1 - 1.1e-11 44.5 3.1 1.1e-11 44.5 3.1 4.0 4 1 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AMK78016.1 - 8.5e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK78016.1 - 0.00024 21.0 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK78016.1 - 0.0013 18.6 0.0 0.0045 16.9 0.0 1.9 2 0 0 2 2 2 1 GHKL domain ApoLp-III PF07464.11 AMK78016.1 - 0.2 11.8 3.8 0.88 9.7 0.0 3.3 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) HTH_IclR PF09339.10 AMK78016.1 - 2.4 8.0 6.7 1.9 8.4 1.6 3.1 3 0 0 3 3 3 0 IclR helix-turn-helix domain PMC2NT PF08066.12 AMK78016.1 - 2.7 8.8 12.7 48 4.7 0.8 5.3 4 2 1 5 5 5 0 PMC2NT (NUC016) domain PIG-L PF02585.17 AMK78017.1 - 7.5e-20 71.9 0.0 1.5e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2156 PF09924.9 AMK78018.1 - 2.2e-94 315.8 0.3 3e-94 315.4 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) LPG_synthase_TM PF03706.13 AMK78018.1 - 6e-12 45.7 34.6 6e-12 45.7 34.6 3.0 2 1 1 3 3 3 1 Lysylphosphatidylglycerol synthase TM region VirJ PF06057.11 AMK78019.1 - 5.3e-72 241.7 0.0 1.1e-71 240.7 0.0 1.5 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) DUF900 PF05990.12 AMK78019.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 AMK78020.1 - 2.3e-23 83.1 0.2 8.3e-19 68.2 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK78020.1 - 1.8e-18 67.9 2.3 2.2e-18 67.7 2.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK78020.1 - 1.6e-11 43.9 0.1 1.1e-08 34.6 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 AMK78020.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 AMK78020.1 - 0.00041 20.2 0.0 0.0011 18.9 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 AMK78020.1 - 0.12 12.5 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein BAAT_C PF08840.11 AMK78020.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ParBc PF02195.18 AMK78021.1 - 0.017 15.4 0.1 0.031 14.6 0.1 1.6 1 1 0 1 1 1 0 ParB-like nuclease domain OprB PF04966.12 AMK78022.1 - 5.6e-34 118.2 3.5 6.9e-34 117.9 3.5 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family IMS_HHH PF11798.8 AMK78022.1 - 0.099 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif P-II PF00543.22 AMK78023.1 - 3.4e-18 66.1 0.0 3.9e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II ACR_tran PF00873.19 AMK78024.1 - 7.7e-280 931.0 21.8 8.8e-280 930.8 21.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK78024.1 - 7.6e-14 51.4 36.6 5.6e-10 38.7 5.0 2.8 3 1 0 3 3 3 2 MMPL family HlyD_D23 PF16576.5 AMK78025.1 - 1.6e-48 164.8 0.1 2.5e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK78025.1 - 8.1e-20 71.5 1.7 5.1e-14 52.9 0.2 2.5 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK78025.1 - 5.7e-09 35.7 0.2 3.1e-07 30.1 0.0 3.1 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.20 AMK78025.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.9 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS SNARE PF05739.19 AMK78025.1 - 0.73 9.9 1.8 1.5 8.9 0.3 2.1 2 0 0 2 2 2 0 SNARE domain OEP PF02321.18 AMK78026.1 - 1.9e-47 161.5 21.6 1.8e-24 86.6 11.2 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein YrhK PF14145.6 AMK78027.1 - 0.017 15.0 1.7 0.029 14.2 1.7 1.4 1 0 0 1 1 1 0 YrhK-like protein DUF2721 PF11026.8 AMK78027.1 - 0.069 13.0 11.9 0.028 14.3 6.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) MrpF_PhaF PF04066.13 AMK78027.1 - 0.85 10.1 7.0 2.5 8.6 3.7 2.7 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) E1-E2_ATPase PF00122.20 AMK78028.1 - 3.7e-48 163.4 2.0 7.1e-48 162.5 0.0 2.5 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AMK78028.1 - 9.4e-19 68.5 0.1 2.4e-18 67.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 AMK78028.1 - 4.6e-17 61.5 0.0 1.2e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 AMK78028.1 - 3.2e-16 59.6 6.5 3.2e-16 59.6 6.5 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 AMK78028.1 - 2.9e-05 24.1 0.0 6.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 AMK78028.1 - 0.0037 17.0 1.7 0.013 15.3 0.5 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK78028.1 - 0.0041 17.6 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 AMK78028.1 - 0.17 11.8 0.0 0.73 9.8 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family DUF1761 PF08570.10 AMK78028.1 - 0.79 10.0 5.4 0.25 11.6 0.2 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1761) Carb_anhydrase PF00194.21 AMK78029.1 - 4.1e-45 154.3 0.1 1.1e-44 152.9 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Cytochrom_C_2 PF01322.20 AMK78030.1 - 0.00011 23.1 0.1 0.00076 20.4 0.1 2.1 1 1 0 1 1 1 1 Cytochrome C' Cytochrom_B562 PF07361.11 AMK78030.1 - 0.016 15.9 0.1 0.039 14.6 0.1 1.7 1 1 0 1 1 1 0 Cytochrome b562 DUF2490 PF10677.9 AMK78031.1 - 7.7e-41 140.1 2.5 8.8e-41 139.9 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) Sulfate_transp PF00916.20 AMK78032.1 - 2.8e-59 200.8 21.5 2.8e-59 200.8 21.5 1.5 1 1 1 2 2 2 1 Sulfate permease family MFS_MOT1 PF16983.5 AMK78032.1 - 7.1e-07 29.6 1.1 7.1e-07 29.6 1.1 4.2 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily STAS PF01740.21 AMK78032.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain DUF2309 PF10070.9 AMK78033.1 - 1.5e-237 790.7 0.0 1.7e-237 790.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) DUF4602 PF15375.6 AMK78033.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Proton_antipo_M PF00361.20 AMK78034.1 - 2.2e-36 125.6 30.1 4.2e-35 121.4 9.4 3.2 3 1 0 3 3 3 2 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AMK78034.1 - 4.2e-07 29.9 1.2 4.2e-07 29.9 1.2 2.4 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus PhnA PF03831.14 AMK78035.1 - 3.1e-34 116.7 8.2 4.3e-34 116.2 8.2 1.3 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 AMK78035.1 - 9.2e-15 54.3 3.9 1.5e-14 53.6 3.9 1.3 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AMK78035.1 - 0.00052 19.5 1.8 0.00052 19.5 1.8 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 AMK78035.1 - 0.0024 17.7 0.8 0.0042 17.0 0.8 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Cys_rich_CPCC PF14206.6 AMK78035.1 - 0.011 15.6 0.9 0.015 15.1 0.9 1.2 1 0 0 1 1 1 0 Cysteine-rich CPCC zf-ribbon_3 PF13248.6 AMK78035.1 - 0.022 14.2 5.2 0.82 9.2 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.9 AMK78035.1 - 0.029 14.4 2.8 0.45 10.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HypA PF01155.19 AMK78035.1 - 0.11 12.5 0.3 0.24 11.5 0.3 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HYPF PF07503.12 AMK78035.1 - 0.21 11.4 4.1 5.8 6.8 0.8 2.3 2 0 0 2 2 2 0 HypF finger TFIIS_C PF01096.18 AMK78035.1 - 0.25 11.2 3.9 6.4 6.7 0.6 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 AMK78035.1 - 0.25 11.3 3.8 1.8 8.6 0.5 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AMK78035.1 - 0.42 10.8 4.9 1.6 8.9 0.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.6 AMK78035.1 - 0.48 10.9 3.6 1.2 9.5 3.6 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar PADR1 PF08063.12 AMK78035.1 - 0.56 10.0 3.7 1.9 8.3 3.8 1.7 1 1 0 1 1 1 0 PADR1 (NUC008) domain DUF4379 PF14311.6 AMK78035.1 - 0.72 10.3 4.3 2.6 8.5 0.4 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-RRN7 PF11781.8 AMK78035.1 - 1.2 8.9 4.5 4 7.2 4.5 1.9 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_2 PF13240.6 AMK78035.1 - 3 7.7 7.2 11 5.9 4.9 2.6 2 1 0 2 2 2 0 zinc-ribbon domain AIRS_C PF02769.22 AMK78036.1 - 1e-37 129.7 0.0 1.6e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AMK78036.1 - 1.1e-15 58.1 0.4 2.2e-15 57.1 0.4 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DUF2066 PF09839.9 AMK78037.1 - 8e-62 208.7 1.9 9.1e-62 208.5 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2066) CPP1-like PF11833.8 AMK78038.1 - 0.01 15.5 3.1 0.011 15.4 2.4 1.4 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3040 PF11239.8 AMK78039.1 - 0.043 14.1 0.4 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Sigma54_activat PF00158.26 AMK78040.1 - 7.5e-71 237.2 0.1 1.1e-70 236.7 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK78040.1 - 1.7e-28 99.1 0.0 3.2e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AMK78040.1 - 3.8e-27 95.1 0.0 1.7e-26 92.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK78040.1 - 9.1e-12 44.6 1.5 5.3e-11 42.1 0.6 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK78040.1 - 6.7e-07 29.4 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK78040.1 - 5.9e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AMK78040.1 - 0.0013 18.2 0.2 0.091 12.1 0.2 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AMK78040.1 - 0.0023 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 AMK78040.1 - 0.02 14.4 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 AMK78040.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FleQ PF06490.11 AMK78040.1 - 0.098 13.0 0.0 0.75 10.2 0.0 2.3 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ MCM PF00493.23 AMK78040.1 - 0.1 11.7 0.0 0.33 10.0 0.0 1.8 1 1 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 AMK78040.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain HATPase_c PF02518.26 AMK78041.1 - 1.9e-18 67.0 0.1 3.4e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78041.1 - 6.7e-13 48.5 0.6 1.8e-12 47.1 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AMK78041.1 - 5.3e-08 33.1 0.0 9.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AMK78041.1 - 2.6e-05 24.2 0.0 6.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK78041.1 - 4.4e-05 23.4 0.0 0.00014 21.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AMK78041.1 - 0.00037 20.7 0.0 0.00088 19.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AMK78041.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK78041.1 - 0.0026 17.6 0.2 0.0074 16.2 0.2 1.8 1 1 0 1 1 1 1 GHKL domain PAS_7 PF12860.7 AMK78041.1 - 0.091 12.9 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold Ammonium_transp PF00909.21 AMK78043.1 - 8e-108 360.7 33.4 9.1e-108 360.5 33.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Exo_endo_phos PF03372.23 AMK78044.1 - 1.1e-18 67.6 0.1 1.7e-18 67.0 0.1 1.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AMK78044.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Hydrolase_4 PF12146.8 AMK78045.1 - 3.6e-58 196.7 0.0 4.3e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AMK78045.1 - 2.6e-12 47.8 0.3 4.3e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AMK78045.1 - 4.2e-12 46.2 0.1 1.5e-10 41.2 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AMK78045.1 - 0.00082 18.9 0.2 0.06 12.8 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF900 PF05990.12 AMK78045.1 - 0.0041 16.7 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 AMK78045.1 - 0.0059 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 AMK78045.1 - 0.0071 16.2 0.0 2.8 7.7 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_GDSL_2 PF13472.6 AMK78045.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DLH PF01738.18 AMK78045.1 - 0.015 14.8 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 AMK78045.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.8 2 1 0 2 2 2 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 AMK78045.1 - 0.092 12.7 0.1 5.9 6.8 0.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 AMK78045.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.25 AMK78045.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ParBc PF02195.18 AMK78046.1 - 2.8e-09 37.1 0.1 1.8e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_23 PF13384.6 AMK78046.1 - 0.019 14.7 0.0 0.058 13.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Pox_C7_F8A PF03287.14 AMK78046.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Poxvirus C7/F8A protein Aldedh PF00171.22 AMK78047.1 - 2.5e-114 382.3 0.0 3.4e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 AMK78047.1 - 2e-92 309.9 0.0 3.2e-92 309.2 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 AMK78047.1 - 5.1e-33 113.9 0.1 1.7e-32 112.3 0.1 2.0 1 0 0 1 1 1 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 AMK78047.1 - 0.028 14.6 1.7 0.073 13.3 0.0 2.8 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain VipB PF05943.12 AMK78048.1 - 4.4e-26 91.6 0.0 1.6e-13 50.3 0.0 2.2 1 1 1 2 2 2 2 Type VI secretion protein, EvpB/VC_A0108, tail sheath T6SS_VipA PF05591.12 AMK78048.1 - 8.9e-08 32.1 0.0 1.4e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 SDF PF00375.18 AMK78049.1 - 3.1e-103 345.8 32.7 3.5e-103 345.6 32.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Insulin_TMD PF17870.1 AMK78049.1 - 4.8 7.3 7.4 0.58 10.3 1.7 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PTR2 PF00854.21 AMK78051.1 - 2.3e-59 201.2 18.7 1.1e-29 103.6 0.7 2.2 1 1 1 2 2 2 2 POT family MFS_1 PF07690.16 AMK78051.1 - 6e-21 74.8 31.2 6e-21 74.8 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Malic_M PF03949.15 AMK78052.1 - 1.5e-89 299.7 0.0 2.7e-89 298.8 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 AMK78052.1 - 5.4e-65 218.6 0.0 7.5e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Imp-YgjV PF10688.9 AMK78053.1 - 1.4e-34 119.3 11.2 1.5e-34 119.1 11.2 1.0 1 0 0 1 1 1 1 Bacterial inner membrane protein RhodobacterPufX PF11511.8 AMK78053.1 - 0.6 9.8 4.3 0.41 10.3 1.5 2.2 2 1 0 2 2 2 0 Intrinsic membrane protein PufX HDOD PF08668.12 AMK78054.1 - 8.2e-38 129.9 0.3 2.9e-37 128.1 0.1 1.8 2 0 0 2 2 2 1 HDOD domain HD PF01966.22 AMK78054.1 - 7.8e-06 26.1 0.0 4.8e-05 23.6 0.0 2.2 2 1 1 3 3 3 1 HD domain HD_2 PF12917.7 AMK78054.1 - 0.017 14.9 0.2 0.05 13.4 0.0 1.8 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme TYW3 PF02676.14 AMK78054.1 - 0.028 13.8 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 Curlin_rpt PF07012.12 AMK78054.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Curlin associated repeat ADH_N PF08240.12 AMK78055.1 - 3.1e-20 72.1 0.2 5.1e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AMK78055.1 - 4.3e-09 36.5 0.2 2.1e-08 34.2 0.2 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AMK78055.1 - 1.6e-05 24.5 2.3 6.2e-05 22.6 0.5 2.5 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 AMK78055.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 AMK78055.1 - 0.0021 19.1 0.0 0.004 18.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.16 AMK78055.1 - 0.0026 17.4 0.1 0.0045 16.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 AMK78055.1 - 0.006 15.9 0.4 0.0084 15.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 AMK78055.1 - 0.054 13.5 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 AMK78055.1 - 0.13 12.9 0.1 0.36 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PsbQ PF05757.11 AMK78057.1 - 0.068 12.9 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF5546 PF17700.1 AMK78057.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5546) TAT_signal PF10518.9 AMK78057.1 - 2.3 8.2 4.9 0.49 10.3 0.5 2.4 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PFL-like PF02901.15 AMK78058.1 - 8.4e-106 355.1 0.0 1.4e-105 354.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 AMK78058.1 - 0.0082 16.7 0.0 0.25 11.9 0.0 2.7 2 0 0 2 2 2 1 Glycine radical DUF3029 PF11230.8 AMK78058.1 - 0.081 11.3 0.0 0.17 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Radical_SAM PF04055.21 AMK78060.1 - 5.4e-19 69.2 0.0 9.4e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AMK78060.1 - 8e-09 35.9 4.9 3.4e-07 30.6 4.9 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_6 PF12837.7 AMK78060.1 - 2.2e-05 24.3 18.4 6.9e-05 22.8 2.1 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4 PF00037.27 AMK78060.1 - 0.00012 21.7 0.4 0.00012 21.7 0.4 3.5 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_16 PF13484.6 AMK78060.1 - 0.0028 18.6 10.6 0.0068 17.3 0.1 2.9 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AMK78060.1 - 0.0069 17.0 9.5 0.0069 17.0 9.5 2.6 2 1 2 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AMK78060.1 - 0.009 16.1 3.0 0.009 16.1 3.0 3.7 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_9 PF13187.6 AMK78060.1 - 0.013 15.7 11.3 0.013 15.7 11.3 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_14 PF13394.6 AMK78060.1 - 0.019 15.1 0.3 3.6 7.7 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 AMK78060.1 - 0.07 13.7 1.8 0.07 13.7 1.8 3.5 4 0 0 4 4 4 0 4Fe-4S binding domain Palm_thioest PF02089.15 AMK78062.1 - 1.9e-08 34.5 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 AMK78062.1 - 2.8e-05 23.9 0.1 5.7e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 AMK78062.1 - 6.9e-05 22.5 0.0 0.00017 21.2 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 2) PGAP1 PF07819.13 AMK78062.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 AMK78062.1 - 0.0009 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 AMK78062.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 AMK78062.1 - 0.0051 16.4 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 AMK78062.1 - 0.09 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) YcgR PF07317.12 AMK78064.1 - 8.5e-22 77.1 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulator YcgR Ferlin_C PF16165.5 AMK78065.1 - 0.033 14.1 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus HATPase_c PF02518.26 AMK78066.1 - 7.6e-19 68.3 0.0 1.4e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78066.1 - 2.4e-12 46.7 1.7 5.2e-12 45.6 1.0 2.0 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AMK78066.1 - 0.00046 20.5 0.0 0.0014 19.0 0.0 1.9 1 0 0 1 1 1 1 HAMP domain sCache_3_2 PF17203.4 AMK78066.1 - 0.011 15.9 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 Single cache domain 3 HATPase_c_2 PF13581.6 AMK78066.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 AMK78066.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 GHKL domain HATPase_c_3 PF13589.6 AMK78066.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_like PF16736.5 AMK78066.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Single Cache-like Response_reg PF00072.24 AMK78067.1 - 3.1e-25 88.5 0.0 4.3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK78067.1 - 2.8e-24 85.0 0.2 5.2e-24 84.1 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HTH_11 PF08279.12 AMK78067.1 - 0.0064 16.4 0.1 0.037 14.0 0.1 2.2 1 1 0 1 1 1 1 HTH domain DUF350 PF03994.14 AMK78068.1 - 8.3e-12 45.1 14.8 3e-06 27.3 2.7 2.2 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) Fumarate_red_C PF02300.17 AMK78068.1 - 0.051 13.6 0.9 0.087 12.9 0.6 1.5 1 1 0 1 1 1 0 Fumarate reductase subunit C GSP_synth PF03738.14 AMK78069.1 - 2.5e-145 484.4 0.0 2.8e-145 484.2 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp MAR_sialic_bdg PF10564.9 AMK78070.1 - 0.037 14.1 0.4 0.09 12.8 0.1 1.7 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Form_Nir_trans PF01226.17 AMK78071.1 - 1.4e-62 211.2 30.2 1.5e-62 211.0 30.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter BCHF PF07284.11 AMK78071.1 - 2.6 8.0 6.9 0.89 9.6 3.5 2.0 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Cyanate_lyase PF02560.14 AMK78072.1 - 4.3e-36 122.6 0.0 5.7e-36 122.2 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 AMK78072.1 - 0.015 15.7 0.6 0.021 15.1 0.6 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 AMK78073.1 - 3.6e-32 111.8 0.0 5e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 AMK78073.1 - 7.2e-20 71.4 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 AMK78073.1 - 1.9e-15 57.1 1.0 3.1e-15 56.4 1.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 AMK78073.1 - 2.7e-07 30.5 0.1 0.024 14.3 0.1 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C Kdo PF06293.14 AMK78073.1 - 2.4e-06 27.1 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 AMK78073.1 - 9.2e-06 25.7 0.3 0.0062 16.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family SpoIIE PF07228.12 AMK78073.1 - 0.0001 22.3 0.1 0.00017 21.6 0.1 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Seadorna_VP7 PF07387.11 AMK78073.1 - 0.00094 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 AMK78073.1 - 0.002 17.1 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 AMK78073.1 - 0.087 12.4 0.0 0.52 9.8 0.0 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase TonB_dep_Rec PF00593.24 AMK78074.1 - 7.5e-49 167.9 22.6 7.5e-49 167.9 22.6 1.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK78074.1 - 2.7e-22 79.4 0.3 5.4e-22 78.4 0.3 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK78074.1 - 4e-14 52.4 0.3 4.6e-12 45.6 0.1 2.7 2 1 0 2 2 2 2 Outer membrane protein beta-barrel family Porin_O_P PF07396.11 AMK78074.1 - 0.03 13.5 1.3 0.19 10.9 0.3 2.3 2 1 0 2 2 2 0 Phosphate-selective porin O and P ABC_sub_bind PF04392.12 AMK78075.1 - 1.1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter substrate binding protein Pribosyltran PF00156.27 AMK78075.1 - 0.15 11.5 0.1 0.34 10.4 0.1 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase domain EAL PF00563.20 AMK78076.1 - 3.3e-75 252.7 0.3 8.3e-75 251.4 0.3 1.8 1 0 0 1 1 1 1 EAL domain Response_reg PF00072.24 AMK78076.1 - 3.6e-56 188.2 0.7 2.8e-27 95.1 0.1 3.7 3 0 0 3 3 3 2 Response regulator receiver domain GGDEF PF00990.21 AMK78076.1 - 3.7e-48 163.3 0.2 9.9e-48 161.9 0.2 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HATPase_c PF02518.26 AMK78076.1 - 1.1e-28 99.9 0.0 4e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78076.1 - 2.9e-20 72.1 0.1 2e-19 69.4 0.1 2.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AMK78076.1 - 4.4e-13 49.3 5.3 1.9e-12 47.3 5.3 2.2 1 0 0 1 1 1 1 Hpt domain HAMP PF00672.25 AMK78076.1 - 8.5e-07 29.3 0.4 4e-06 27.1 0.4 2.3 1 0 0 1 1 1 1 HAMP domain DUF2222 PF09984.9 AMK78076.1 - 8.2e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) DUF2279 PF10043.9 AMK78077.1 - 0.071 13.9 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) HicA_toxin PF07927.12 AMK78078.1 - 2.8e-05 24.1 0.4 3.8e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, WLM PF08325.10 AMK78078.1 - 0.056 13.5 1.1 0.061 13.4 1.1 1.0 1 0 0 1 1 1 0 WLM domain TraL PF07178.11 AMK78079.1 - 0.034 14.6 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 TraL protein OppC_N PF12911.7 AMK78079.1 - 0.079 12.9 1.9 0.12 12.3 1.9 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Phage_holin_2_4 PF16082.5 AMK78079.1 - 0.08 12.7 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like GST_N_3 PF13417.6 AMK78080.1 - 1e-09 38.6 0.0 2.7e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK78080.1 - 4e-09 36.4 1.9 5.8e-09 35.9 1.6 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AMK78080.1 - 1.5e-07 31.5 0.1 1.9e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 AMK78080.1 - 4.4e-07 30.1 0.0 9.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 AMK78080.1 - 3.5e-05 23.9 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 AMK78080.1 - 0.0081 15.9 0.1 0.02 14.7 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 AMK78080.1 - 0.071 13.7 0.1 0.16 12.5 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 AMK78080.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_N_4 PF17172.4 AMK78080.1 - 0.15 12.8 0.0 0.42 11.4 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain ABC_tran PF00005.27 AMK78081.1 - 1e-45 155.6 0.0 1.4e-21 77.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 AMK78081.1 - 2.1e-23 82.1 0.4 2.6e-21 75.4 0.2 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AMK78081.1 - 1.4e-16 61.2 1.9 0.0016 18.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK78081.1 - 1.2e-07 31.4 6.3 0.5 9.8 0.2 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AMK78081.1 - 2.7e-07 30.2 0.2 0.0073 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK78081.1 - 5.9e-07 29.5 0.0 0.0038 17.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 AMK78081.1 - 3.4e-06 27.4 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 AMK78081.1 - 6.3e-06 26.1 1.0 0.031 14.0 0.1 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_16 PF13191.6 AMK78081.1 - 7e-06 26.5 0.0 0.0008 19.8 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_24 PF13479.6 AMK78081.1 - 2.2e-05 24.3 0.0 0.063 13.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 AMK78081.1 - 2.5e-05 23.4 0.8 0.011 14.8 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 AMK78081.1 - 2.7e-05 24.2 0.0 0.073 13.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 AMK78081.1 - 3.5e-05 23.8 0.1 0.21 11.6 0.0 4.3 4 2 1 5 5 5 1 AAA domain NACHT PF05729.12 AMK78081.1 - 5.1e-05 23.3 0.2 0.057 13.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 AMK78081.1 - 5.9e-05 22.5 0.0 0.86 9.0 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AMK78081.1 - 7.8e-05 23.0 0.0 0.29 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 AMK78081.1 - 9.3e-05 22.6 0.1 0.52 10.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 AMK78081.1 - 0.00019 22.0 0.3 1.3 9.6 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 AMK78081.1 - 0.00037 20.8 0.2 0.25 11.6 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 AMK78081.1 - 0.00044 20.8 5.0 0.22 12.0 0.4 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 AMK78081.1 - 0.0013 19.1 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AMK78081.1 - 0.0014 18.6 0.0 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 AMK78081.1 - 0.004 16.7 0.1 0.36 10.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 AMK78081.1 - 0.0053 16.3 0.2 0.36 10.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 AMK78081.1 - 0.0066 16.1 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 AMK78081.1 - 0.0092 16.1 3.5 1.5 8.8 0.0 3.6 4 0 0 4 4 4 1 Helicase HerA, central domain ATPase_2 PF01637.18 AMK78081.1 - 0.016 15.2 0.1 1 9.2 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 AMK78081.1 - 0.017 15.2 0.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 Dynamin family MukB PF04310.12 AMK78081.1 - 0.017 15.0 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Septin PF00735.18 AMK78081.1 - 0.023 14.0 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 AMK78081.1 - 0.029 14.4 1.2 17 5.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AMK78081.1 - 0.037 13.8 0.0 3.2 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AMK78081.1 - 0.037 14.2 0.7 14 6.0 0.1 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit SL4P PF17618.2 AMK78081.1 - 0.047 13.7 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Roc PF08477.13 AMK78081.1 - 0.05 13.8 0.2 3.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GcpE PF04551.14 AMK78081.1 - 0.061 12.4 0.1 0.095 11.8 0.1 1.2 1 0 0 1 1 1 0 GcpE protein NB-ARC PF00931.22 AMK78081.1 - 0.077 12.2 1.5 1.2 8.3 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 AMK78081.1 - 0.077 12.8 0.2 18 5.1 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 AMK78081.1 - 0.087 12.7 2.3 2.5 8.0 0.1 3.6 4 0 0 4 4 4 0 NTPase PIN7 PF18475.1 AMK78081.1 - 0.15 12.7 0.0 3.4 8.4 0.0 2.9 3 0 0 3 3 3 0 PIN domain TsaE PF02367.17 AMK78081.1 - 0.17 11.9 0.3 22 5.1 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cupin_7 PF12973.7 AMK78082.1 - 6.5e-20 70.8 0.0 1.3e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 ChrR Cupin-like domain DUF4437 PF14499.6 AMK78082.1 - 1.2e-10 41.0 0.0 4.4e-05 22.7 0.0 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4437) Cupin_2 PF07883.11 AMK78082.1 - 1.6e-09 37.3 0.1 0.0012 18.5 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Sigma70_r2 PF04542.14 AMK78083.1 - 1e-17 63.7 2.0 1e-17 63.7 2.0 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 AMK78083.1 - 1.8e-12 46.7 0.0 3.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AMK78083.1 - 5e-11 42.0 0.2 2e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 AMK78083.1 - 0.016 14.7 0.1 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 AMK78083.1 - 0.031 14.2 0.1 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 ECF sigma factor HTH_40 PF14493.6 AMK78083.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NUC205 PF08168.11 AMK78083.1 - 0.063 12.8 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NUC205 domain TnsD PF15978.5 AMK78083.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D GerE PF00196.19 AMK78083.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family PEP-CTERM PF07589.11 AMK78084.1 - 0.0012 18.8 1.9 0.0012 18.8 1.9 2.2 3 0 0 3 3 3 1 PEP-CTERM motif DUF4331 PF14224.6 AMK78085.1 - 1.5e-108 363.7 0.3 1.8e-108 363.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4331) TPR_1 PF00515.28 AMK78086.1 - 8.2e-12 44.4 4.8 0.0059 16.4 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78086.1 - 1.6e-08 34.0 10.8 0.016 15.3 0.6 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK78086.1 - 1.4e-07 32.1 4.0 1.4e-07 32.1 4.0 5.8 6 1 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78086.1 - 3.8e-05 24.1 40.2 0.024 15.5 2.5 7.7 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 AMK78086.1 - 9.2e-05 22.7 25.3 0.0046 17.2 4.4 5.5 4 3 2 6 6 6 4 Tetratricopeptide repeat NARP1 PF12569.8 AMK78086.1 - 0.00062 18.8 0.4 0.14 11.1 0.0 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 AMK78086.1 - 0.00077 19.6 3.1 0.00077 19.6 3.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK78086.1 - 0.0016 18.6 10.6 0.52 10.6 0.4 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 AMK78086.1 - 0.0023 18.0 3.6 0.019 15.1 0.3 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 AMK78086.1 - 0.0024 18.3 42.0 0.044 14.3 5.3 6.3 5 3 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 AMK78086.1 - 0.0041 17.4 12.1 0.032 14.6 0.4 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 AMK78086.1 - 0.0068 15.8 5.5 0.0068 15.8 5.5 4.1 1 1 0 3 3 3 2 MalT-like TPR region TPR_20 PF14561.6 AMK78086.1 - 0.13 12.6 19.2 2.2 8.7 0.2 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK78086.1 - 0.2 11.6 12.8 0.13 12.2 1.8 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 AMK78086.1 - 0.68 10.1 9.5 0.25 11.5 0.7 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 AMK78086.1 - 4.9 7.3 9.0 0.74 9.9 0.9 3.4 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain HupE_UreJ_2 PF13795.6 AMK78087.1 - 1.6e-46 157.8 2.5 2.5e-46 157.1 2.5 1.3 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ PF04955.12 AMK78087.1 - 0.0013 18.2 7.9 0.0033 16.9 7.9 1.7 1 1 0 1 1 1 1 HupE / UreJ protein EF-hand_5 PF13202.6 AMK78087.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 EF hand PIG-Y PF15159.6 AMK78087.1 - 1.5 9.8 6.7 7.1 7.6 0.3 3.5 4 1 0 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y FUSC PF04632.12 AMK78088.1 - 1.4e-15 56.9 22.3 1.4e-15 56.9 22.3 2.5 1 1 0 2 2 2 2 Fusaric acid resistance protein family FUSC_2 PF13515.6 AMK78088.1 - 5.3e-05 23.3 9.7 5.3e-05 23.3 9.7 3.2 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 AMK78088.1 - 0.14 12.3 12.0 0.14 12.3 1.5 2.5 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 Biotin_lipoyl_2 PF13533.6 AMK78089.1 - 6.9e-21 73.8 0.0 1.1e-17 63.5 0.1 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AMK78089.1 - 4.7e-17 61.9 3.9 4.4e-13 48.9 3.9 2.8 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK78089.1 - 8.1e-17 61.9 0.0 1.2e-09 38.8 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 AMK78089.1 - 7.8e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AMK78089.1 - 0.048 13.5 0.0 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme ERM PF00769.19 AMK78089.1 - 0.079 12.8 10.6 0.11 12.3 10.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HlyD_2 PF12700.7 AMK78089.1 - 0.094 11.4 0.2 0.37 9.5 0.0 1.8 2 0 0 2 2 2 0 HlyD family secretion protein Spc7 PF08317.11 AMK78089.1 - 0.2 10.5 8.4 0.32 9.8 8.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BRE1 PF08647.11 AMK78089.1 - 0.25 11.4 7.7 0.66 10.1 7.6 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 AMK78089.1 - 0.5 10.6 10.5 0.1 12.8 3.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF501 PF04417.12 AMK78089.1 - 0.69 9.7 3.2 1.7 8.5 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF501) Ytca PF17090.5 AMK78090.1 - 2.9e-07 30.9 10.1 4.7e-07 30.2 10.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family MarR PF01047.22 AMK78091.1 - 8.2e-14 51.3 0.0 2.1e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 AMK78091.1 - 1.2e-11 44.4 0.0 3e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 MarR family HTH_27 PF13463.6 AMK78091.1 - 2.3e-07 31.2 0.1 5.6e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 AMK78091.1 - 1.1e-05 25.6 0.1 6.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain PadR PF03551.14 AMK78091.1 - 0.00035 20.5 0.2 0.00058 19.8 0.2 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_24 PF13412.6 AMK78091.1 - 0.0004 19.9 0.0 0.00089 18.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 AMK78091.1 - 0.00098 18.9 0.1 0.0021 17.9 0.0 1.7 1 1 1 2 2 2 1 HxlR-like helix-turn-helix TrmB PF01978.19 AMK78091.1 - 0.0028 17.5 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.11 AMK78091.1 - 0.048 13.6 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Penicillinase_R PF03965.16 AMK78091.1 - 0.097 13.0 0.3 0.24 11.7 0.1 1.9 2 1 0 2 2 2 0 Penicillinase repressor OEP PF02321.18 AMK78092.1 - 1.1e-57 194.9 19.1 2e-33 115.8 7.1 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Peptidase_M41 PF01434.18 AMK78093.1 - 6.6e-64 215.3 0.0 1e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AMK78093.1 - 2.5e-45 154.1 0.0 4.8e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AMK78093.1 - 5.7e-13 48.4 0.0 2.8e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 AMK78093.1 - 2.5e-08 34.2 0.1 7.8e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 FtsH Extracellular TIP49 PF06068.13 AMK78093.1 - 1.8e-06 27.4 0.1 1.4e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 AMK78093.1 - 5.1e-05 23.3 0.1 0.00061 19.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AMK78093.1 - 0.00021 21.1 0.0 0.0012 18.6 0.0 2.3 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AMK78093.1 - 0.001 19.5 0.3 0.034 14.5 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 AMK78093.1 - 0.0021 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 AMK78093.1 - 0.0038 17.0 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 AMK78093.1 - 0.0039 17.5 0.1 0.34 11.2 0.1 2.7 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 AMK78093.1 - 0.0069 15.8 0.5 0.014 14.8 0.5 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 AMK78093.1 - 0.0097 16.0 0.0 0.036 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 AMK78093.1 - 0.012 16.1 0.1 0.032 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Cytochrom_C550 PF14495.6 AMK78093.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain AAA_28 PF13521.6 AMK78093.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK78093.1 - 0.079 12.5 0.3 0.74 9.3 0.2 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 AMK78093.1 - 0.14 12.2 0.1 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 AMK78093.1 - 0.16 11.4 0.4 0.31 10.4 0.4 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 AMK78093.1 - 0.17 11.2 0.1 0.6 9.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin SMBP PF16785.5 AMK78094.1 - 0.0052 17.0 3.0 0.0068 16.6 3.0 1.1 1 0 0 1 1 1 1 Small metal-binding protein DUF4148 PF13663.6 AMK78094.1 - 0.013 15.6 0.5 0.025 14.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) TAFII28 PF04719.14 AMK78094.1 - 0.053 13.6 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region FUSC PF04632.12 AMK78094.1 - 0.053 12.0 0.5 0.067 11.7 0.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S8 PF00082.22 AMK78096.1 - 0.0044 16.3 2.9 0.019 14.2 2.7 2.0 1 1 0 1 1 1 1 Subtilase family PEP-CTERM PF07589.11 AMK78096.1 - 0.035 14.2 1.5 0.035 14.2 1.5 2.4 2 0 0 2 2 2 0 PEP-CTERM motif PEP-CTERM PF07589.11 AMK78097.1 - 0.022 14.8 1.3 0.098 12.8 1.3 2.2 1 0 0 1 1 1 0 PEP-CTERM motif DUF2690 PF10901.8 AMK78097.1 - 0.092 13.1 2.1 0.14 12.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2690) Sulfotransfer_3 PF13469.6 AMK78098.1 - 3.9e-25 89.5 0.0 1.2e-24 88.0 0.0 1.8 1 0 0 1 1 1 1 Sulfotransferase family TPR_19 PF14559.6 AMK78098.1 - 1.7e-13 50.9 18.6 4.5e-08 33.5 2.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 AMK78098.1 - 1.1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain TPR_12 PF13424.6 AMK78098.1 - 3.2e-11 43.3 18.8 0.0083 16.4 1.4 5.1 4 1 2 6 6 6 5 Tetratricopeptide repeat SEC-C PF02810.15 AMK78098.1 - 2.7e-10 39.9 7.7 4.5e-10 39.3 7.7 1.4 1 0 0 1 1 1 1 SEC-C motif TPR_2 PF07719.17 AMK78098.1 - 4.5e-10 38.9 18.7 0.0023 17.9 0.3 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78098.1 - 7.7e-10 38.8 17.2 0.0083 16.9 0.0 6.3 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 AMK78098.1 - 1.1e-09 37.7 9.8 0.00034 20.3 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK78098.1 - 5e-09 36.7 15.6 0.0074 16.9 1.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 AMK78098.1 - 3.9e-08 32.9 1.5 0.33 11.3 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78098.1 - 2.6e-06 27.0 3.4 0.015 15.0 0.4 4.0 3 1 1 4 4 4 2 TPR repeat ANAPC3 PF12895.7 AMK78098.1 - 5e-06 26.6 9.3 0.0005 20.2 0.6 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 AMK78098.1 - 0.00025 20.8 0.3 1.2 9.3 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 AMK78098.1 - 0.0039 16.9 0.7 0.0039 16.9 0.7 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 AMK78098.1 - 0.065 13.9 15.0 14 6.6 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat LppC PF04348.13 AMK78098.1 - 0.091 11.5 4.0 0.19 10.5 4.0 1.5 1 0 0 1 1 1 0 LppC putative lipoprotein TPR_20 PF14561.6 AMK78098.1 - 0.18 12.2 6.8 1.1 9.7 0.7 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 AMK78098.1 - 0.19 11.9 8.7 1.7 8.8 0.5 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 AMK78098.1 - 0.44 11.0 5.0 1.7e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK78098.1 - 1.8 8.5 17.3 3.1 7.8 0.1 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat SBP_bac_11 PF13531.6 AMK78099.1 - 2.2e-43 148.7 0.1 2.6e-43 148.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AMK78099.1 - 2.4e-19 70.5 9.2 3.1e-19 70.1 9.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AMK78099.1 - 3.5e-09 36.4 1.1 4.8e-09 36.0 1.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AMK78099.1 - 0.00084 18.5 0.1 0.0025 17.0 0.0 1.7 2 0 0 2 2 2 1 PBP superfamily domain DUF3013 PF11217.8 AMK78099.1 - 0.036 13.9 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) EAL PF00563.20 AMK78100.1 - 3e-40 138.2 0.2 3.9e-40 137.9 0.2 1.1 1 0 0 1 1 1 1 EAL domain PALP PF00291.25 AMK78101.1 - 1.5e-66 224.8 3.3 1.7e-66 224.7 3.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 AMK78101.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Toluene_X PF03349.16 AMK78102.1 - 1.5e-25 89.7 4.9 5.9e-24 84.4 4.9 2.6 1 1 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) Sulf_transp PF04143.14 AMK78103.1 - 4.4e-07 29.8 18.8 3.2e-06 26.9 18.8 2.0 1 1 0 1 1 1 1 Sulphur transport EpuA PF11772.8 AMK78103.1 - 2.4 7.9 8.8 4.9 6.9 1.7 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Sulf_transp PF04143.14 AMK78104.1 - 2.8e-05 23.9 2.9 2.8e-05 23.9 2.9 2.0 2 0 0 2 2 2 1 Sulphur transport FAD_binding_7 PF03441.14 AMK78105.1 - 1.2e-44 152.3 1.6 2e-44 151.5 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AMK78105.1 - 1.1e-32 113.3 0.1 2.1e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase GSHPx PF00255.19 AMK78106.1 - 6.7e-27 93.2 1.6 8.7e-27 92.8 1.6 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 AMK78106.1 - 0.00031 20.6 0.1 0.0004 20.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK78106.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Redoxin cobW PF02492.19 AMK78107.1 - 1.2e-37 129.2 0.0 1.4e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AMK78107.1 - 3.7e-06 26.1 0.1 0.012 14.6 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 AMK78107.1 - 0.00038 20.1 0.2 0.016 14.8 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 AMK78107.1 - 0.0019 18.6 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 AMK78107.1 - 0.015 15.8 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 AMK78107.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 AMK78107.1 - 0.025 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 AMK78107.1 - 0.038 14.5 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 AMK78107.1 - 0.057 13.3 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 AMK78107.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 AMK78107.1 - 0.071 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AMK78107.1 - 0.074 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AMK78107.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 AMK78107.1 - 0.096 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 AMK78107.1 - 0.12 12.3 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 AMK78107.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 AMK78107.1 - 0.15 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain UreF PF01730.16 AMK78108.1 - 5.2e-42 143.6 11.5 6.9e-42 143.2 11.5 1.2 1 0 0 1 1 1 1 UreF DUF2189 PF09955.9 AMK78108.1 - 0.089 13.0 0.8 0.23 11.7 0.0 1.9 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2189) UreE_C PF05194.12 AMK78109.1 - 7.7e-24 84.0 0.1 1.4e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UreE_N PF02814.15 AMK78109.1 - 8.9e-15 54.0 0.0 1.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain Pilus_CpaD PF09476.10 AMK78111.1 - 0.047 13.4 1.2 0.084 12.6 1.2 1.3 1 1 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2795 PF11387.8 AMK78111.1 - 0.18 12.1 1.0 1.3 9.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2795) FUSC PF04632.12 AMK78111.1 - 0.47 8.9 2.1 0.56 8.7 2.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Amidohydro_1 PF01979.20 AMK78112.1 - 9.6e-78 261.9 0.4 1.3e-77 261.4 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 AMK78112.1 - 8e-56 187.6 2.7 1.5e-55 186.7 2.7 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 AMK78112.1 - 3.3e-09 36.8 0.5 2.9e-05 23.7 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family Urease_beta PF00699.20 AMK78113.1 - 3e-46 155.4 0.0 3.3e-46 155.3 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit YcgR_2 PF12945.7 AMK78113.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar protein YcgR Urease_gamma PF00547.18 AMK78114.1 - 2e-47 159.6 0.1 2.2e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 Urease, gamma subunit NEL PF14496.6 AMK78114.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting PhdYeFM_antitox PF02604.19 AMK78115.1 - 3.1e-24 84.6 0.1 3.7e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system PHD_like PF12910.7 AMK78115.1 - 0.0061 16.6 0.0 0.0066 16.5 0.0 1.1 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system YoeB_toxin PF06769.14 AMK78116.1 - 1.8e-38 130.5 0.2 2e-38 130.3 0.2 1.0 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system ParE_toxin PF05016.15 AMK78116.1 - 0.0001 22.8 0.0 0.00013 22.5 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE tRNA-Thr_ED PF08915.11 AMK78117.1 - 0.024 14.7 0.8 0.05 13.7 0.1 1.9 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase HTH_9 PF08221.11 AMK78117.1 - 0.061 13.4 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RelB_N PF18506.1 AMK78118.1 - 8.7e-17 60.7 1.5 1.1e-16 60.4 1.5 1.1 1 0 0 1 1 1 1 RelB Antitoxin alpha helical domain UreD PF01774.17 AMK78119.1 - 4.7e-44 150.9 0.0 6.2e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein zf-LSD1 PF06943.12 AMK78119.1 - 0.44 10.4 2.6 8 6.4 0.1 2.4 2 0 0 2 2 2 0 LSD1 zinc finger Phage_holin_4_2 PF04020.13 AMK78120.1 - 0.059 14.1 0.8 0.071 13.8 0.8 1.1 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV ABC_tran PF00005.27 AMK78121.1 - 1.2e-30 106.8 0.0 2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK78121.1 - 9.7e-09 35.4 0.0 0.00078 19.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK78121.1 - 0.00089 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 AMK78121.1 - 0.0017 17.9 0.1 0.27 10.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AMK78121.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 AMK78121.1 - 0.0064 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 AMK78121.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AMK78121.1 - 0.0072 16.9 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain PerC PF06069.11 AMK78121.1 - 0.02 15.2 0.0 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 PerC transcriptional activator AAA_15 PF13175.6 AMK78121.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AMK78121.1 - 0.024 14.9 0.2 0.066 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AMK78121.1 - 0.028 13.8 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AMK78121.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 AMK78121.1 - 0.033 13.4 0.1 0.041 13.1 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 AMK78121.1 - 0.042 13.8 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 AMK78121.1 - 0.043 14.2 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 AMK78121.1 - 0.051 13.6 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AMK78121.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AMK78121.1 - 0.17 11.6 0.0 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 AMK78121.1 - 0.2 11.4 0.1 0.37 10.5 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.19 AMK78121.1 - 0.21 11.0 0.1 0.48 9.8 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 AMK78122.1 - 3.2e-27 95.7 0.0 4.8e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AMK78122.1 - 1.7e-09 37.4 0.0 4.1e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 AMK78122.1 - 1.7e-07 31.4 0.2 0.00025 20.9 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK78122.1 - 8.3e-06 25.4 0.0 1.8e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK78122.1 - 9.7e-06 26.2 0.2 2.3e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AMK78122.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AMK78122.1 - 0.00051 19.7 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 AMK78122.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF2813 PF11398.8 AMK78122.1 - 0.0021 17.4 0.0 0.0048 16.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) RsgA_GTPase PF03193.16 AMK78122.1 - 0.0045 16.9 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AMK78122.1 - 0.0066 16.8 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AMK78122.1 - 0.01 15.6 0.5 0.066 12.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AMK78122.1 - 0.012 15.9 0.5 0.15 12.4 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AMK78122.1 - 0.025 15.0 0.1 0.058 13.8 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dyp_perox PF04261.12 AMK78122.1 - 0.026 13.5 0.3 0.033 13.2 0.3 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family AAA_33 PF13671.6 AMK78122.1 - 0.15 12.2 0.1 0.56 10.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AMK78122.1 - 0.19 11.3 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 AMK78122.1 - 0.25 10.0 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 AMK78123.1 - 2.9e-37 128.3 32.7 3.9e-37 127.9 32.7 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_2 PF02653.16 AMK78125.1 - 6.3e-54 182.9 37.9 1e-53 182.2 37.9 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component HEAT_2 PF13646.6 AMK78125.1 - 7.3e-08 32.7 11.7 0.0012 19.1 2.0 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 AMK78125.1 - 0.00056 20.0 0.7 0.7 10.3 0.1 3.5 3 0 0 3 3 3 2 HEAT repeat IBN_N PF03810.19 AMK78125.1 - 0.12 12.3 0.8 0.87 9.6 0.2 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain Peripla_BP_5 PF13433.6 AMK78126.1 - 1.8e-171 570.0 0.1 2.1e-171 569.8 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 AMK78126.1 - 1e-64 219.4 0.0 1.2e-64 219.2 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Response_reg PF00072.24 AMK78132.1 - 7.8e-27 93.7 0.0 1.4e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 AMK78132.1 - 4.5e-24 85.1 0.2 7.3e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78132.1 - 5.4e-19 68.0 0.4 1.8e-18 66.3 0.4 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AMK78132.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cript PF10235.9 AMK78132.1 - 0.57 10.8 4.6 1.1 9.9 4.6 1.4 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Response_reg PF00072.24 AMK78133.1 - 2e-27 95.6 0.0 4.4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK78133.1 - 6.5e-17 60.8 0.2 1.1e-16 60.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AMK78133.1 - 0.0022 17.7 0.1 0.0046 16.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78133.1 - 0.008 15.9 0.3 0.23 11.3 0.0 2.9 2 1 1 3 3 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AMK78133.1 - 0.0096 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 AMK78133.1 - 0.12 12.5 0.6 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short_C2 PF13561.6 AMK78134.1 - 6.5e-65 219.0 5.1 7.4e-65 218.8 5.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AMK78134.1 - 1.4e-56 191.1 3.7 1.6e-56 190.8 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK78134.1 - 2.4e-14 53.7 1.0 3.9e-14 53.0 1.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 AMK78134.1 - 3.9e-06 26.9 0.5 4.8e-06 26.6 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AMK78134.1 - 0.00024 20.6 0.4 0.0013 18.3 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SAM_LFY PF01698.16 AMK78134.1 - 0.0061 16.5 0.5 0.019 14.9 0.0 2.1 2 1 0 2 2 2 1 Floricaula / Leafy protein SAM domain DUF1776 PF08643.10 AMK78134.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Acyl_transf_1 PF00698.21 AMK78135.1 - 2.5e-38 132.4 1.2 3.1e-38 132.1 1.2 1.1 1 0 0 1 1 1 1 Acyl transferase domain BMC PF00936.19 AMK78135.1 - 0.07 13.1 2.6 0.13 12.3 2.1 1.8 1 1 0 1 1 1 0 BMC domain ACP_syn_III_C PF08541.10 AMK78136.1 - 5.3e-36 122.7 0.3 2.6e-35 120.5 0.2 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 AMK78136.1 - 1.1e-32 111.7 0.4 2.5e-32 110.6 0.2 1.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 AMK78136.1 - 3.3e-06 26.6 3.4 3.6e-06 26.5 0.3 2.3 2 1 1 3 3 3 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 AMK78136.1 - 4.3e-05 23.0 0.0 0.00033 20.0 0.0 2.0 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein SpoVAD PF07451.11 AMK78136.1 - 0.0031 16.3 0.6 0.019 13.7 0.2 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Chal_sti_synt_N PF00195.19 AMK78136.1 - 0.0043 16.5 1.4 0.021 14.3 1.0 2.1 2 1 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Thiolase_C PF02803.18 AMK78136.1 - 0.011 15.4 0.2 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Thiolase, C-terminal domain Chal_sti_synt_C PF02797.15 AMK78136.1 - 0.027 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain ketoacyl-synt PF00109.26 AMK78136.1 - 0.29 10.7 2.8 2.3 7.7 0.1 3.0 1 1 2 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain FA_synthesis PF02504.15 AMK78137.1 - 4.1e-98 328.4 3.4 4.7e-98 328.2 3.4 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein PTA_PTB PF01515.19 AMK78137.1 - 9.1e-06 25.2 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase Peripla_BP_6 PF13458.6 AMK78137.1 - 0.05 13.3 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein YceD PF02620.17 AMK78138.1 - 1.2e-20 73.8 1.2 1.6e-20 73.5 1.2 1.1 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Maf PF02545.14 AMK78139.1 - 1.7e-44 151.6 0.0 1.9e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HDOD PF08668.12 AMK78140.1 - 4.9e-60 202.4 0.0 7.5e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK78140.1 - 0.00029 21.1 0.1 0.00062 20.0 0.1 1.6 1 1 0 1 1 1 1 HD domain HEPN_LA2681 PF18733.1 AMK78140.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 LA2681-like HEPN SLT PF01464.20 AMK78141.1 - 7.8e-31 106.2 0.2 1e-30 105.8 0.2 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 AMK78141.1 - 8.2e-06 25.3 0.1 0.00021 20.7 0.1 2.1 1 1 1 2 2 2 1 Transglycosylase SLT domain DUF4124 PF13511.6 AMK78141.1 - 7e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) TetR_C_20 PF17925.1 AMK78141.1 - 0.093 13.0 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ATP-grasp PF02222.22 AMK78142.1 - 9.8e-53 178.2 0.0 1.7e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AMK78142.1 - 3.3e-10 39.9 0.0 8.9e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Epimerase PF01370.21 AMK78142.1 - 1.5e-05 24.6 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.17 AMK78142.1 - 2.8e-05 23.7 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AMK78142.1 - 0.00086 19.4 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain RmlD_sub_bind PF04321.17 AMK78142.1 - 0.0018 17.4 0.2 0.003 16.7 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 AMK78142.1 - 0.004 16.5 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 AMK78142.1 - 0.036 13.9 0.2 0.07 13.0 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_4 PF13535.6 AMK78142.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ThiF PF00899.21 AMK78142.1 - 0.15 11.4 0.1 1.2 8.4 0.0 2.2 2 1 0 2 2 2 0 ThiF family MutS_V PF00488.21 AMK78143.1 - 2.3e-25 89.7 0.0 4.2e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 AMK78143.1 - 5.5e-07 30.0 0.0 1.5e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 MutS domain III AAA_14 PF13173.6 AMK78143.1 - 0.018 15.1 0.0 0.23 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 AMK78143.1 - 0.021 15.3 0.0 0.096 13.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ferrochelatase PF00762.19 AMK78144.1 - 3.3e-110 368.1 0.0 4.1e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 AMK78144.1 - 0.00042 20.6 0.0 0.02 15.2 0.0 2.6 3 0 0 3 3 3 1 CbiX GTP_cyclohydroI PF01227.22 AMK78145.1 - 1.9e-75 252.2 0.3 2.1e-75 252.1 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 AMK78145.1 - 0.04 14.1 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein MAPKK1_Int PF08923.10 AMK78145.1 - 0.054 13.3 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting Dus PF01207.17 AMK78146.1 - 2.7e-86 289.5 0.0 3.2e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 AMK78146.1 - 0.029 13.8 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein PcrB PF01884.17 AMK78146.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 PcrB family Response_reg PF00072.24 AMK78150.1 - 5.9e-48 161.7 3.6 6.1e-26 90.8 1.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AMK78150.1 - 6.7e-32 110.3 0.4 1.4e-31 109.3 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78150.1 - 1.6e-19 69.7 1.6 5.4e-19 68.0 0.1 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 AMK78150.1 - 3.8e-10 39.9 1.7 3.8e-10 39.9 1.7 3.1 3 0 0 3 3 3 1 Hpt domain HAMP PF00672.25 AMK78150.1 - 0.00019 21.7 1.7 0.0004 20.7 0.2 2.4 2 0 0 2 2 2 1 HAMP domain Sigma54_activat PF00158.26 AMK78151.1 - 2.6e-73 245.2 0.6 2e-72 242.4 0.2 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK78151.1 - 1.3e-24 86.6 0.1 3e-24 85.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AMK78151.1 - 1.1e-20 74.2 0.0 4.3e-20 72.2 0.0 2.1 1 0 0 1 1 1 1 Sigma-54 interaction domain PAS PF00989.25 AMK78151.1 - 1.3e-11 44.5 0.0 3.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold AAA_5 PF07728.14 AMK78151.1 - 9.6e-09 35.4 0.3 4.6e-08 33.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) PAS_8 PF13188.7 AMK78151.1 - 4.6e-08 32.9 0.0 2.6e-06 27.3 0.0 2.9 2 0 0 2 2 2 1 PAS domain HTH_8 PF02954.19 AMK78151.1 - 1.5e-07 31.1 0.3 5.1e-07 29.4 0.3 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA PF00004.29 AMK78151.1 - 8.2e-07 29.5 0.1 0.00016 22.1 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PAS_4 PF08448.10 AMK78151.1 - 1.8e-06 28.2 0.0 3.3e-05 24.1 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AMK78151.1 - 1.9e-06 28.1 0.0 6.7e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain AAA_2 PF07724.14 AMK78151.1 - 7e-06 26.3 0.0 0.00015 22.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 AMK78151.1 - 1.4e-05 24.9 0.7 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 AMK78151.1 - 0.00024 20.6 0.3 0.012 15.0 0.3 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 AMK78151.1 - 0.0015 18.3 0.4 0.0053 16.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain PAS_10 PF13596.6 AMK78151.1 - 0.0044 17.6 0.0 0.017 15.7 0.0 2.0 2 0 0 2 2 1 1 PAS domain AAA_16 PF13191.6 AMK78151.1 - 0.0093 16.4 0.3 0.063 13.7 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AMK78151.1 - 0.017 15.4 0.2 2.5 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 AMK78151.1 - 0.026 13.6 0.3 0.06 12.4 0.3 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.11 AMK78151.1 - 0.033 14.1 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 AMK78151.1 - 0.04 13.1 0.1 0.096 11.9 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 AMK78151.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 AMK78151.1 - 0.079 12.4 0.3 13 5.1 0.1 2.9 3 0 0 3 3 3 0 Bacterial TniB protein LolA PF03548.15 AMK78152.1 - 1.6e-45 154.8 0.1 1.9e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 AMK78152.1 - 0.0091 15.4 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 2 Predicted periplasmic protein (DUF2092) Transgly PF00912.22 AMK78153.1 - 1.6e-59 200.4 0.0 2.4e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase UB2H PF14814.6 AMK78153.1 - 5.1e-22 77.7 0.0 1.1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain Transpeptidase PF00905.22 AMK78153.1 - 6.4e-17 61.7 0.0 6.8e-16 58.3 0.0 2.2 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain UvrB_inter PF17757.1 AMK78153.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 UvrB interaction domain Transport_MerF PF11431.8 AMK78153.1 - 6.8 6.7 5.4 4.4 7.3 3.0 1.9 2 0 0 2 2 2 0 Membrane transport protein MerF DUF1223 PF06764.11 AMK78154.1 - 0.0036 17.4 0.1 0.08 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1223) DUF836 PF05768.14 AMK78154.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) SfLAP PF11139.8 AMK78154.1 - 0.022 14.2 18.0 0.8 9.1 13.0 2.2 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein Glutaredoxin PF00462.24 AMK78154.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DUF308 PF03729.13 AMK78154.1 - 0.057 13.8 1.1 0.057 13.8 1.1 3.5 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) OATP PF03137.20 AMK78154.1 - 0.065 11.5 0.4 0.11 10.8 0.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TNFR_16_TM PF18422.1 AMK78154.1 - 1.4 8.9 3.4 7 6.7 1.0 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4096 PF13340.6 AMK78155.1 - 1.7e-24 85.8 2.8 3.5e-24 84.8 2.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK78156.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK78156.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK78156.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK78156.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PilZ PF07238.14 AMK78157.1 - 1.7e-07 31.5 0.0 1.9e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 PilZ domain SprA-related PF12118.8 AMK78158.1 - 1.8e-38 132.5 5.5 2.2e-38 132.3 5.5 1.1 1 0 0 1 1 1 1 SprA-related family DUF1730 PF08331.10 AMK78159.1 - 4.6e-22 77.7 0.0 8.9e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 AMK78159.1 - 1.1e-20 74.3 2.1 1.9e-20 73.5 2.1 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AMK78159.1 - 4.7e-07 30.3 4.8 1.1e-06 29.1 4.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AMK78159.1 - 1.3e-05 25.2 2.1 0.0036 17.5 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK78159.1 - 2.4e-05 24.3 2.9 0.073 13.2 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AMK78159.1 - 0.00058 19.8 12.7 0.0047 17.0 3.1 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AMK78159.1 - 0.0022 18.4 2.4 0.23 11.9 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AMK78159.1 - 0.0025 17.5 11.1 0.003 17.3 2.3 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_2 PF12797.7 AMK78159.1 - 0.0076 16.3 12.5 0.23 11.6 4.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 AMK78159.1 - 0.098 13.6 11.0 2.7 9.1 3.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AMK78159.1 - 0.1 12.8 3.3 1.1 9.4 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AMK78159.1 - 0.29 11.3 10.4 10 6.4 10.4 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AMK78159.1 - 1.8 9.2 8.5 64 4.2 9.6 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AMK78159.1 - 2.2 9.0 12.2 0.89 10.2 3.5 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain DUF4231 PF14015.6 AMK78160.1 - 0.042 14.3 0.7 0.07 13.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF5368 PF17336.2 AMK78160.1 - 0.069 13.3 0.4 0.14 12.3 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5368) LPAM_1 PF08139.12 AMK78160.1 - 1.4 9.5 7.6 0.22 12.1 2.1 2.4 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Carb_kinase PF01256.17 AMK78163.1 - 1.2e-63 214.8 0.7 1.9e-63 214.2 0.7 1.3 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 AMK78163.1 - 7.2e-43 146.4 0.1 1.3e-42 145.6 0.1 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus TPR_16 PF13432.6 AMK78163.1 - 0.0011 19.6 2.2 0.029 15.0 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Phos_pyr_kin PF08543.12 AMK78163.1 - 0.0052 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TsaE PF02367.17 AMK78164.1 - 1.4e-39 135.0 0.0 1.7e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 AMK78164.1 - 0.00019 21.9 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 AMK78164.1 - 0.0028 17.8 0.0 0.003 17.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AMK78164.1 - 0.009 15.9 0.1 0.027 14.4 0.1 1.8 1 1 0 1 1 1 1 NACHT domain cobW PF02492.19 AMK78164.1 - 0.014 15.0 0.2 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AMK78164.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AMK78164.1 - 0.038 14.4 0.0 0.051 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AMK78164.1 - 0.044 14.3 0.0 0.081 13.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 AMK78164.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 AMK78164.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 AMK78164.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Amidase_3 PF01520.18 AMK78165.1 - 2e-49 168.1 0.6 4.4e-49 166.9 0.6 1.6 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase LysM PF01476.20 AMK78165.1 - 8.6e-11 41.7 0.0 2.8e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 LysM domain AMIN PF11741.8 AMK78165.1 - 1.7e-09 37.7 0.2 8.8e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 AMIN domain GSK-3_bind PF05350.12 AMK78165.1 - 0.00023 20.6 3.7 0.00023 20.6 3.7 1.8 2 0 0 2 2 2 1 Glycogen synthase kinase-3 binding Thioredoxin_7 PF13899.6 AMK78165.1 - 0.15 12.2 0.5 4 7.7 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like MutL_C PF08676.11 AMK78166.1 - 8.4e-48 161.9 0.5 1.7e-47 160.9 0.5 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 AMK78166.1 - 1.3e-39 134.5 0.0 2.7e-39 133.5 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AMK78166.1 - 3.8e-12 46.2 0.0 1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AMK78166.1 - 3.4e-06 27.5 0.0 7.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPPT PF01715.17 AMK78167.1 - 1e-88 297.0 0.0 1.3e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AMK78167.1 - 2.3e-09 37.0 0.2 2.6e-05 23.8 0.0 3.2 2 1 0 3 3 3 2 Isopentenyl transferase AAA_16 PF13191.6 AMK78167.1 - 0.0019 18.6 0.3 0.0076 16.6 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain Hydin_ADK PF17213.3 AMK78167.1 - 0.0047 17.2 0.3 0.0076 16.6 0.3 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain TIP49 PF06068.13 AMK78167.1 - 0.0055 16.0 0.1 0.0084 15.4 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Band_7 PF01145.25 AMK78167.1 - 0.0066 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family AAA PF00004.29 AMK78167.1 - 0.0076 16.7 0.1 0.02 15.3 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 AMK78167.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AMK78167.1 - 0.017 14.4 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.12 AMK78167.1 - 0.017 14.8 0.1 0.098 12.4 0.1 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 AMK78167.1 - 0.028 13.5 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 AMK78167.1 - 0.063 13.0 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 AMK78167.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 AMK78167.1 - 0.067 12.9 0.2 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Cytidylate kinase SRPRB PF09439.10 AMK78167.1 - 0.13 11.7 0.0 0.6 9.5 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 AMK78167.1 - 0.38 10.3 2.0 1.1 8.7 0.1 2.5 3 0 0 3 3 3 0 AAA domain 5-FTHF_cyc-lig PF01812.20 AMK78168.1 - 7.5e-35 120.5 0.1 8.5e-35 120.3 0.1 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Orn_DAP_Arg_deC PF00278.22 AMK78169.1 - 8.4e-13 48.4 0.0 8.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 AMK78169.1 - 7.9e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ala_racemase_N PF01168.20 AMK78169.1 - 0.052 13.2 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Methyltransf_11 PF08241.12 AMK78171.1 - 2.9e-24 85.5 0.0 1.8e-23 83.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78171.1 - 2.6e-22 79.3 0.1 2.8e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK78171.1 - 2.1e-18 66.6 0.0 4.6e-18 65.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 AMK78171.1 - 1.4e-17 63.9 0.3 1.8e-17 63.5 0.3 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 AMK78171.1 - 1.2e-14 54.5 0.1 1.9e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78171.1 - 5.3e-12 46.4 0.0 1.8e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK78171.1 - 1.4e-11 44.2 0.0 7.9e-11 41.7 0.0 2.1 3 0 0 3 3 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 AMK78171.1 - 6.8e-06 25.7 0.1 2.4e-05 24.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.10 AMK78171.1 - 2.1e-05 24.2 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 AMK78171.1 - 3.4e-05 23.8 0.0 9.7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TPMT PF05724.11 AMK78171.1 - 7.7e-05 22.4 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.6 AMK78171.1 - 0.0004 21.4 0.1 0.0021 19.1 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 AMK78171.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 AMK78171.1 - 0.00053 19.6 0.1 0.00086 18.9 0.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_29 PF03141.16 AMK78171.1 - 0.00077 18.1 0.0 0.001 17.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 AMK78171.1 - 0.00095 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DOT1 PF08123.13 AMK78171.1 - 0.0018 17.8 0.0 0.0084 15.7 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 AMK78171.1 - 0.007 15.9 0.0 0.04 13.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 AMK78171.1 - 0.0099 15.3 0.0 0.039 13.4 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 AMK78171.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 AMK78171.1 - 0.015 15.0 0.0 0.22 11.2 0.0 2.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 AMK78171.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 AMK78171.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 AMK78171.1 - 0.11 12.2 0.0 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 DNA methylase WHAMM-JMY_N PF15920.5 AMK78171.1 - 0.11 12.4 0.5 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated Methyltr_RsmB-F PF01189.17 AMK78171.1 - 0.13 11.9 0.0 3.6 7.2 0.0 2.3 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F eIF3m_C_helix PF18005.1 AMK78171.1 - 0.4 10.4 4.3 0.28 10.9 0.7 2.3 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix ThiF PF00899.21 AMK78173.1 - 1.1e-34 119.9 0.0 1.4e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 AMK78173.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 AMK78173.1 - 0.0064 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.19 AMK78173.1 - 0.0076 15.5 0.3 0.0099 15.1 0.3 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 AMK78173.1 - 0.015 15.8 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 AMK78173.1 - 0.1 12.9 1.1 0.51 10.6 1.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TatD_DNase PF01026.21 AMK78174.1 - 8.5e-34 117.1 0.1 4.3e-33 114.8 0.0 2.0 1 1 0 2 2 2 1 TatD related DNase ABC_tran PF00005.27 AMK78175.1 - 2.3e-57 193.3 0.0 5.2e-30 104.7 0.0 3.3 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AMK78175.1 - 4.4e-18 66.1 5.9 0.00026 20.9 0.0 5.1 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AMK78175.1 - 3.4e-14 52.6 5.8 5.8e-12 45.5 5.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 AMK78175.1 - 1.4e-05 24.7 1.2 0.058 13.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 AMK78175.1 - 3.7e-05 23.3 7.8 0.065 12.7 0.1 4.3 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK78175.1 - 3.8e-05 24.3 12.3 0.0008 20.0 0.5 3.4 3 0 0 3 3 3 2 AAA domain DLIC PF05783.11 AMK78175.1 - 3.9e-05 22.7 0.3 0.0056 15.6 0.0 2.2 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) SbcCD_C PF13558.6 AMK78175.1 - 5.1e-05 23.4 1.0 0.75 10.1 0.0 4.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 AMK78175.1 - 5.1e-05 23.3 0.1 0.32 11.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 AMK78175.1 - 0.00015 22.0 0.2 0.057 13.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AMK78175.1 - 0.00037 20.9 1.4 1.8 8.9 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 AMK78175.1 - 0.0014 19.2 1.5 2.6 8.6 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.6 AMK78175.1 - 0.0019 18.4 0.4 2 8.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 AMK78175.1 - 0.0028 17.4 0.1 0.69 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 AMK78175.1 - 0.0035 16.1 4.6 0.31 9.6 0.0 3.4 4 1 0 4 4 4 2 AAA domain AAA_15 PF13175.6 AMK78175.1 - 0.0077 16.0 0.0 1.8 8.2 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 AMK78175.1 - 0.0082 15.4 1.4 0.67 9.1 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.6 AMK78175.1 - 0.022 14.8 0.0 2.9 7.9 0.0 3.2 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 AMK78175.1 - 0.025 14.2 1.1 2.6 7.6 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AMK78175.1 - 0.027 14.4 0.4 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 AMK78175.1 - 0.033 14.4 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AMK78175.1 - 0.04 13.6 0.4 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AMK78175.1 - 0.046 13.3 0.1 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AMK78175.1 - 0.048 13.6 0.5 10 6.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 AMK78175.1 - 0.091 12.5 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 AMK78175.1 - 0.14 12.4 0.7 8.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 AMK78175.1 - 0.15 11.5 0.2 3.3 7.1 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family SRP54 PF00448.22 AMK78175.1 - 0.19 11.3 1.8 5.1 6.7 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 AMK78175.1 - 0.2 11.6 2.1 2.3 8.1 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF1843 PF08898.10 AMK78175.1 - 0.23 12.0 1.9 0.58 10.7 0.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) AAA PF00004.29 AMK78175.1 - 0.25 11.8 0.7 3.5 8.1 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MRP-L46 PF11788.8 AMK78175.1 - 0.35 11.6 3.3 0.69 10.7 3.3 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 AAA_25 PF13481.6 AMK78175.1 - 0.37 10.4 2.8 15 5.1 0.1 3.7 3 1 0 3 3 3 0 AAA domain DUF3584 PF12128.8 AMK78175.1 - 1.1 6.7 13.2 0.77 7.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) Hfq PF17209.3 AMK78176.1 - 1.6e-30 104.5 0.4 1.9e-30 104.3 0.4 1.0 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 AMK78176.1 - 0.0015 18.2 0.2 0.0023 17.6 0.2 1.5 1 1 0 1 1 1 1 LSM domain GTP-bdg_N PF13167.6 AMK78177.1 - 9.5e-31 106.3 0.3 2.2e-30 105.2 0.0 1.8 2 0 0 2 2 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 AMK78177.1 - 9.1e-28 96.7 9.8 1.1e-27 96.4 8.8 1.7 2 0 0 2 2 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 AMK78177.1 - 2e-22 79.4 0.0 8.5e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AMK78177.1 - 1.4e-08 34.4 0.3 6.9e-08 32.2 0.0 2.2 2 1 1 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 AMK78177.1 - 7.9e-07 29.1 0.2 0.04 13.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 AMK78177.1 - 6.3e-05 22.6 2.6 0.0014 18.3 0.1 2.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 AMK78177.1 - 8.6e-05 22.1 1.1 0.00093 18.7 1.1 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 AMK78177.1 - 0.00025 20.6 0.0 0.074 12.6 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AMK78177.1 - 0.00092 19.3 0.0 0.0025 17.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 AMK78177.1 - 0.004 17.7 0.1 0.022 15.2 0.0 2.2 1 1 1 2 2 2 1 ABC transporter SRPRB PF09439.10 AMK78177.1 - 0.0045 16.5 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 AMK78177.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 AMK78177.1 - 0.017 14.3 0.8 1 8.5 0.1 2.4 2 1 0 3 3 3 0 G-protein alpha subunit ATP_bind_1 PF03029.17 AMK78177.1 - 0.017 14.9 0.2 0.046 13.5 0.1 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Band_7 PF01145.25 AMK78178.1 - 4.1e-27 95.3 2.6 6.3e-27 94.7 2.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family HflK_N PF12221.8 AMK78178.1 - 2.7e-16 59.3 7.8 5.1e-16 58.4 7.8 1.5 1 0 0 1 1 1 1 Bacterial membrane protein N terminal DivIVA PF05103.13 AMK78178.1 - 0.068 13.3 0.6 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 DivIVA protein TM_PBP2_N PF16296.5 AMK78178.1 - 0.14 12.3 0.6 2.4 8.3 0.1 2.4 2 0 0 2 2 2 0 N-terminal of TM subunit in PBP-dependent ABC transporters Band_7 PF01145.25 AMK78179.1 - 2.4e-27 96.1 4.0 3.3e-27 95.6 4.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AMK78179.1 - 0.019 14.6 0.2 0.032 13.9 0.2 1.4 1 1 0 1 1 1 0 SPFH domain-Band 7 family ComA PF02679.15 AMK78179.1 - 0.042 13.3 0.2 0.24 10.8 0.1 2.0 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) tRNA-synt_His PF13393.6 AMK78180.1 - 6.7e-117 390.2 0.4 8.6e-117 389.8 0.4 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HTH_47 PF16221.5 AMK78180.1 - 0.094 12.3 0.7 12 5.6 0.0 3.0 3 0 0 3 3 3 0 winged helix-turn-helix Polysacc_deac_2 PF04748.13 AMK78180.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Adenylsucc_synt PF00709.21 AMK78181.1 - 3.4e-177 589.6 0.2 3.9e-177 589.4 0.2 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Rhodanese PF00581.20 AMK78182.1 - 2.1e-28 99.0 0.0 3.2e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain ADH_zinc_N PF00107.26 AMK78183.1 - 4.1e-29 101.2 0.1 6.8e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 AMK78183.1 - 4.5e-28 98.9 0.0 8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 AMK78183.1 - 5.3e-13 48.8 0.2 1.7e-10 40.8 0.0 2.6 2 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 AMK78183.1 - 0.058 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 AMK78183.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 AMK78183.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AMK78184.1 - 1.7e-36 125.3 0.0 2.7e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AMK78184.1 - 2.8e-16 60.2 0.0 3.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.22 AMK78184.1 - 0.0029 18.4 0.0 0.005 17.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PEP-CTERM PF07589.11 AMK78185.1 - 3.5e-06 26.8 0.2 9.5e-06 25.5 0.2 1.8 1 0 0 1 1 1 1 PEP-CTERM motif TPR_19 PF14559.6 AMK78186.1 - 1.2e-48 163.5 78.7 1.1e-06 29.1 0.2 15.1 8 5 9 18 18 18 14 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78186.1 - 4.3e-45 148.2 58.4 9.8e-05 22.2 0.0 22.0 23 0 0 23 23 22 10 Tetratricopeptide repeat TPR_16 PF13432.6 AMK78186.1 - 5e-43 145.5 42.1 3.5e-08 34.0 0.2 14.3 13 2 1 14 14 13 11 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78186.1 - 3.5e-40 133.3 42.3 0.02 15.7 0.1 19.8 11 7 11 22 22 21 10 Tetratricopeptide repeat TPR_8 PF13181.6 AMK78186.1 - 1.6e-31 105.9 39.5 0.0013 18.8 0.0 19.3 21 0 0 21 21 20 6 Tetratricopeptide repeat TPR_1 PF00515.28 AMK78186.1 - 9.4e-28 94.9 51.6 3.1e-05 23.6 0.0 18.2 19 2 1 20 20 19 6 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK78186.1 - 1.4e-24 86.1 31.4 3.1e-05 24.1 0.1 10.4 5 3 4 10 10 10 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 AMK78186.1 - 2.9e-23 80.5 39.9 0.0023 18.2 0.0 16.7 16 2 1 17 17 16 4 Tetratricopeptide repeat TPR_9 PF13371.6 AMK78186.1 - 1.3e-22 79.7 29.0 0.0016 18.5 1.0 12.2 8 4 5 13 13 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 AMK78186.1 - 2.8e-19 69.2 55.2 0.0064 16.8 0.1 15.3 10 4 4 15 15 15 5 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78186.1 - 1.2e-15 56.9 57.3 0.00047 19.8 1.4 14.7 14 4 5 19 19 17 5 TPR repeat TPR_15 PF13429.6 AMK78186.1 - 5.8e-14 52.0 37.5 4.4e-06 26.1 0.3 6.4 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 AMK78186.1 - 3.1e-11 43.2 64.2 1.1 10.0 0.0 19.4 21 0 0 21 21 20 2 Tetratricopeptide repeat TPR_20 PF14561.6 AMK78186.1 - 7.6e-10 39.0 51.5 0.056 13.8 0.1 12.9 7 5 5 12 12 12 4 Tetratricopeptide repeat PknG_TPR PF16918.5 AMK78186.1 - 3.8e-07 29.2 13.0 0.027 13.2 0.0 7.1 5 2 3 8 8 8 2 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 AMK78186.1 - 4.6e-07 29.4 30.4 0.25 11.4 0.0 13.1 17 0 0 17 17 12 2 Tetratricopeptide repeat Coatomer_E PF04733.14 AMK78186.1 - 6.7e-07 29.0 25.9 0.0014 18.1 1.8 6.0 3 1 3 7 7 7 2 Coatomer epsilon subunit ChAPs PF09295.10 AMK78186.1 - 4.8e-06 25.8 6.8 0.52 9.2 0.1 5.0 3 1 1 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 AMK78186.1 - 2.4e-05 24.0 8.4 1.3 8.7 0.1 6.4 5 3 2 7 7 7 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 AMK78186.1 - 4.2e-05 23.8 13.4 7 7.6 0.1 11.4 15 0 0 15 15 11 0 Tetratricopeptide repeat PPR PF01535.20 AMK78186.1 - 0.00048 20.2 1.6 78 3.9 0.0 7.2 9 0 0 9 9 6 0 PPR repeat DUF4919 PF16266.5 AMK78186.1 - 0.0088 16.0 12.1 0.063 13.2 0.3 5.3 5 2 1 6 6 6 1 Domain of unknown function (DUF4919) HTH_57 PF18679.1 AMK78186.1 - 0.016 15.5 0.3 0.096 13.0 0.3 2.4 1 0 0 1 1 1 0 ThcOx helix turn helix domain Imm57 PF15596.6 AMK78186.1 - 0.017 15.5 1.3 0.18 12.1 0.1 3.0 3 0 0 3 3 3 0 Immunity protein 57 Fis1_TPR_C PF14853.6 AMK78186.1 - 0.029 14.4 18.8 0.77 9.9 0.1 7.6 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat YfiO PF13525.6 AMK78186.1 - 0.23 11.2 30.6 0.44 10.2 0.7 8.8 6 3 4 10 10 9 0 Outer membrane lipoprotein HEAT_2 PF13646.6 AMK78186.1 - 0.61 10.5 4.0 2 8.8 0.0 3.6 4 0 0 4 4 3 0 HEAT repeats BTAD PF03704.17 AMK78186.1 - 1.7 9.1 20.9 0.98 9.8 0.2 7.9 4 2 5 10 10 10 0 Bacterial transcriptional activator domain HATPase_c PF02518.26 AMK78187.1 - 3.5e-22 79.0 0.0 9.1e-22 77.7 0.0 1.7 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78187.1 - 2.6e-10 40.2 3.4 3.3e-10 39.8 0.0 2.7 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AMK78187.1 - 4.5e-06 26.5 0.0 8.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AMK78187.1 - 8.6e-06 25.7 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AMK78187.1 - 0.00016 21.9 0.1 0.00049 20.3 0.0 1.9 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 AMK78187.1 - 0.0018 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 AMK78187.1 - 0.013 15.5 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 0 PAS fold Med21 PF11221.8 AMK78187.1 - 0.019 15.3 2.1 0.048 13.9 2.1 1.7 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HATPase_c_5 PF14501.6 AMK78187.1 - 0.11 12.5 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 GHKL domain IF-2B PF01008.17 AMK78187.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family MbeD_MobD PF04899.12 AMK78187.1 - 4.2 7.6 6.9 9 6.5 0.6 3.3 3 0 0 3 3 3 0 MbeD/MobD like DUF1043 PF06295.12 AMK78187.1 - 9.7 6.2 8.0 1.5 8.8 3.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Sigma54_activat PF00158.26 AMK78188.1 - 5.2e-65 218.2 0.1 8e-65 217.6 0.1 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 AMK78188.1 - 1.8e-27 95.7 0.2 3.6e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 AMK78188.1 - 5.3e-20 72.0 0.0 2.9e-19 69.5 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 AMK78188.1 - 5.8e-08 32.4 0.2 5.8e-08 32.4 0.2 1.9 2 0 0 2 2 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK78188.1 - 1.5e-06 28.2 0.0 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK78188.1 - 5.2e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_30 PF13556.6 AMK78188.1 - 8.6e-05 22.3 1.6 0.0001 22.0 0.0 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MCM PF00493.23 AMK78188.1 - 0.00012 21.3 0.0 0.00027 20.1 0.0 1.5 1 1 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 AMK78188.1 - 0.00016 21.1 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 AMK78188.1 - 0.0014 18.5 0.0 0.0044 16.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) HTH_28 PF13518.6 AMK78188.1 - 0.0029 17.7 0.1 0.0086 16.2 0.0 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78188.1 - 0.0031 17.2 0.1 0.012 15.4 0.1 2.0 1 0 0 1 1 1 1 Homeodomain-like domain AAA_30 PF13604.6 AMK78188.1 - 0.0055 16.4 0.1 0.019 14.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain HTH_20 PF12840.7 AMK78188.1 - 0.014 15.5 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_2 PF07724.14 AMK78188.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HTH_11 PF08279.12 AMK78188.1 - 0.025 14.5 0.0 0.095 12.7 0.0 2.0 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 AMK78188.1 - 0.026 14.1 0.2 0.09 12.4 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 AMK78188.1 - 0.06 13.0 0.7 0.25 11.0 0.1 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain AAA_19 PF13245.6 AMK78188.1 - 0.082 13.2 0.2 0.9 9.9 0.2 2.4 1 1 0 1 1 1 0 AAA domain HTH_Tnp_ISL3 PF13542.6 AMK78188.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 FliE PF02049.18 AMK78189.1 - 3.9e-30 103.8 5.4 4e-30 103.8 4.9 1.2 1 1 0 1 1 1 1 Flagellar hook-basal body complex protein FliE DUF86 PF01934.17 AMK78189.1 - 0.018 14.9 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 SRP68 PF16969.5 AMK78189.1 - 0.043 12.8 1.0 0.046 12.7 1.0 1.0 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 DUF4129 PF13559.6 AMK78189.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) YscJ_FliF PF01514.17 AMK78190.1 - 3.5e-69 232.4 1.7 3.5e-69 232.4 1.7 2.9 3 0 0 3 3 3 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 AMK78190.1 - 2.7e-47 160.9 4.4 2.7e-47 160.9 4.4 2.6 3 0 0 3 3 3 2 Flagellar M-ring protein C-terminal ParD_antitoxin PF03693.14 AMK78190.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH FliG_C PF01706.16 AMK78191.1 - 3.4e-42 143.0 9.8 7.5e-38 129.0 1.8 3.2 3 0 0 3 3 3 3 FliG C-terminal domain FliG_N PF14842.6 AMK78191.1 - 1.1e-37 128.7 3.6 2.9e-29 101.7 0.1 2.8 3 0 0 3 3 3 2 FliG N-terminal domain FliG_M PF14841.6 AMK78191.1 - 7.2e-31 106.2 4.4 2.3e-25 88.6 0.6 3.1 3 0 0 3 3 3 2 FliG middle domain MgtE_N PF03448.17 AMK78191.1 - 3e-06 27.8 10.5 0.0023 18.5 1.0 3.8 4 1 0 4 4 4 3 MgtE intracellular N domain FliH PF02108.16 AMK78192.1 - 1e-34 119.4 0.7 1.6e-34 118.7 0.7 1.3 1 0 0 1 1 1 1 Flagellar assembly protein FliH Yae1_N PF09811.9 AMK78192.1 - 0.0011 18.6 6.9 0.0011 18.6 6.9 2.0 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Laps PF10169.9 AMK78192.1 - 0.14 12.7 0.1 0.22 12.1 0.1 1.3 1 0 0 1 1 1 0 Learning-associated protein HNH_repeat PF18780.1 AMK78192.1 - 3 7.7 10.1 1.3 8.9 1.4 2.6 2 0 0 2 2 2 0 Homing endonuclease repeat ATP-synt_ab PF00006.25 AMK78193.1 - 2.2e-72 243.2 0.0 2.8e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 AMK78193.1 - 1.6e-29 101.6 0.2 2.6e-29 100.9 0.2 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 AMK78193.1 - 0.00014 22.3 2.0 0.00019 21.9 0.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 AMK78193.1 - 0.15 12.6 0.2 0.29 11.6 0.2 1.5 1 0 0 1 1 1 0 ABC transporter FliJ PF02050.16 AMK78194.1 - 3.1e-25 88.8 24.9 3.1e-25 88.8 24.9 1.4 1 1 1 2 2 2 1 Flagellar FliJ protein Myb_DNA-bind_5 PF13873.6 AMK78194.1 - 0.0097 16.0 1.8 0.026 14.6 1.4 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain YscO-like PF16789.5 AMK78194.1 - 0.14 12.2 16.1 0.3 11.1 16.1 1.5 1 1 0 1 1 1 0 YscO-like protein XhlA PF10779.9 AMK78194.1 - 1.3 9.3 5.4 22 5.3 1.3 2.8 2 1 1 3 3 3 0 Haemolysin XhlA SlyX PF04102.12 AMK78194.1 - 2.1 9.0 13.8 1.1 10.0 6.4 2.8 2 1 0 2 2 2 0 SlyX Exonuc_VII_L PF02601.15 AMK78194.1 - 5 6.6 12.8 6.3 6.3 12.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Flg_hook PF02120.16 AMK78195.1 - 3.6e-23 81.2 0.7 3.6e-23 81.2 0.7 2.8 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK Ribosomal_S6 PF01250.17 AMK78196.1 - 5.3e-26 90.7 0.0 8.6e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Ribosomal_S18 PF01084.20 AMK78197.1 - 3e-25 88.2 0.1 3.7e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 DUF2232 PF09991.9 AMK78198.1 - 1.8e-06 27.4 30.7 0.0018 17.5 10.0 2.2 2 1 0 2 2 2 2 Predicted membrane protein (DUF2232) Ribosomal_L9_C PF03948.14 AMK78199.1 - 1.8e-25 89.2 0.7 3.2e-25 88.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AMK78199.1 - 1.2e-20 72.7 0.2 2.7e-20 71.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Epimerase PF01370.21 AMK78200.1 - 4.7e-48 163.8 0.1 5.8e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK78200.1 - 8.6e-20 71.4 0.1 1.4e-19 70.7 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AMK78200.1 - 7.1e-08 31.9 0.0 1.2e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 AMK78200.1 - 4.5e-07 29.1 0.0 1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AMK78200.1 - 0.00054 19.2 0.0 0.8 8.8 0.1 2.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AMK78200.1 - 0.00056 19.1 0.4 0.093 11.9 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein FIST PF08495.10 AMK78201.1 - 9.1e-35 120.2 0.7 1.6e-34 119.4 0.7 1.4 1 0 0 1 1 1 1 FIST N domain FIST_C PF10442.9 AMK78201.1 - 8.8e-18 64.5 2.4 2.5e-14 53.4 0.4 2.5 2 0 0 2 2 2 2 FIST C domain GGDEF PF00990.21 AMK78202.1 - 7.1e-50 168.9 0.3 4e-49 166.4 0.0 2.2 2 1 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AMK78202.1 - 3.8e-07 30.3 0.0 9.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AMK78202.1 - 4.8e-06 26.8 0.0 1.8e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK78202.1 - 5e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK78202.1 - 8.4e-05 22.5 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AMK78202.1 - 0.00013 22.2 0.0 0.00034 20.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold Retrotrans_gag PF03732.17 AMK78202.1 - 0.019 15.2 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein FlgN PF05130.12 AMK78202.1 - 2.4 8.7 9.3 9 6.8 1.9 2.5 2 1 0 2 2 2 0 FlgN protein PPDK_N PF01326.19 AMK78203.1 - 5.6e-116 387.4 0.0 8e-116 386.9 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AMK78203.1 - 4.2e-58 196.8 0.0 6.9e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AMK78203.1 - 6.3e-25 86.7 1.1 1.5e-24 85.5 1.1 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain RelB_leu_zip PF16180.5 AMK78203.1 - 0.19 11.7 0.0 20 5.2 0.0 2.8 2 0 0 2 2 2 0 RelB leucine zipper PEP-CTERM PF07589.11 AMK78204.1 - 0.015 15.4 1.4 0.042 13.9 1.4 1.9 1 0 0 1 1 1 0 PEP-CTERM motif Glycos_transf_N PF04413.16 AMK78205.1 - 5e-68 228.3 0.2 7.9e-68 227.6 0.2 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glycos_transf_1 PF00534.20 AMK78205.1 - 0.00012 21.6 0.0 0.00054 19.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AMK78205.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEDD_Tnp_IS110 PF01548.17 AMK78205.1 - 0.095 12.6 0.0 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 Transposase Arginosuc_synth PF00764.19 AMK78206.1 - 1.7e-155 518.1 0.0 1.9e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 AMK78206.1 - 0.0034 16.9 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 AMK78206.1 - 0.0098 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Pox_LP_H2 PF03356.15 AMK78207.1 - 0.077 12.9 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Viral late protein H2 PIRT PF15099.6 AMK78207.1 - 0.13 11.8 0.0 17 5.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family TraE PF05309.11 AMK78207.1 - 0.99 8.8 4.1 0.85 9.0 2.2 1.8 2 1 0 2 2 2 0 TraE protein Cytochrome_CBB3 PF13442.6 AMK78208.1 - 6.2e-06 26.4 0.6 1.4e-05 25.4 0.6 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK78208.1 - 0.0015 19.6 0.6 0.0033 18.5 0.6 1.6 1 1 0 1 1 1 1 Cytochrome c TP_methylase PF00590.20 AMK78209.1 - 4e-54 183.8 0.0 9.7e-54 182.5 0.0 1.7 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 AMK78209.1 - 2.3e-30 105.1 0.6 4.9e-29 100.8 0.5 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 AMK78209.1 - 4.5e-18 64.7 5.7 1.7e-17 62.9 5.7 2.1 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 AMK78209.1 - 2.9e-06 26.6 0.2 2.9e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 AMK78209.1 - 0.00017 21.7 0.9 0.0014 18.7 0.4 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase VBS PF08913.10 AMK78209.1 - 0.012 16.1 3.1 0.026 15.0 1.5 2.1 2 0 0 2 2 2 0 Vinculin Binding Site Peripla_BP_4 PF13407.6 AMK78209.1 - 0.019 14.5 0.8 0.099 12.2 0.3 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain Semialdhyde_dh PF01118.24 AMK78209.1 - 0.065 13.7 0.2 0.2 12.1 0.2 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Katanin_con80 PF13925.6 AMK78209.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 con80 domain of Katanin ThiF PF00899.21 AMK78209.1 - 0.21 10.9 0.8 1 8.7 0.8 2.2 1 1 0 1 1 1 0 ThiF family TusA PF01206.17 AMK78210.1 - 8.9e-16 57.5 0.0 9.9e-16 57.3 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA HAD PF12710.7 AMK78211.1 - 1.2e-36 126.8 0.1 1.5e-36 126.6 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AMK78211.1 - 0.0028 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 AMK78211.1 - 0.044 13.9 0.2 0.068 13.3 0.2 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK78211.1 - 0.66 9.7 1.8 9 5.9 0.0 2.7 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase NUDIX PF00293.28 AMK78212.1 - 6.2e-27 94.2 0.1 7.6e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 AMK78212.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Metallophos PF00149.28 AMK78213.1 - 7.5e-11 42.9 0.2 1.4e-10 42.0 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK78213.1 - 3.5e-05 24.1 0.6 6.5e-05 23.2 0.6 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phe_hydrox_dim PF07976.12 AMK78213.1 - 0.11 12.6 0.0 0.53 10.3 0.0 2.0 2 1 0 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain NUDIX PF00293.28 AMK78214.1 - 2.3e-12 47.1 0.0 2.6e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain AA_kinase PF00696.28 AMK78215.1 - 7.3e-29 101.1 0.1 9.8e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 AMK78215.1 - 2.2e-05 24.6 0.1 5e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AMK78215.1 - 3.1e-05 24.3 0.0 6.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AMK78215.1 - 3.6e-05 23.7 0.0 9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AlbA_2 PF04326.14 AMK78216.1 - 7.8e-11 42.4 0.0 1.1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Putative DNA-binding domain Voltage_CLC PF00654.20 AMK78216.1 - 0.61 9.3 2.0 5.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Voltage gated chloride channel MreB_Mbl PF06723.13 AMK78217.1 - 2.5e-11 43.0 0.0 3.3e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 MreB/Mbl protein ILVD_EDD PF00920.21 AMK78218.1 - 1e-219 730.5 1.8 1.2e-219 730.3 1.8 1.0 1 0 0 1 1 1 1 Dehydratase family DUF4154 PF13689.6 AMK78218.1 - 0.074 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like Ribosomal_S27 PF01599.19 AMK78218.1 - 1.4 9.2 5.4 6.5 7.0 0.4 3.4 4 0 0 4 4 4 0 Ribosomal protein S27a SH3_3 PF08239.11 AMK78219.1 - 2.4e-06 27.7 0.0 4.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF5383 PF17355.2 AMK78219.1 - 0.0002 21.7 0.1 0.00031 21.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5383) HOOK PF05622.12 AMK78219.1 - 0.001 17.3 7.6 0.0012 17.1 7.6 1.1 1 0 0 1 1 1 1 HOOK protein MCU PF04678.13 AMK78219.1 - 0.0077 16.3 3.7 0.017 15.2 3.7 1.7 1 1 0 1 1 1 1 Mitochondrial calcium uniporter DUF3287 PF11690.8 AMK78219.1 - 0.015 15.1 0.4 0.028 14.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF3972 PF13118.6 AMK78219.1 - 0.023 15.1 7.4 2.1 8.8 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3972) SH3_4 PF06347.13 AMK78219.1 - 0.036 13.9 0.0 0.084 12.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial SH3 domain ApoO PF09769.9 AMK78219.1 - 0.044 13.8 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 Apolipoprotein O KIAA1430 PF13879.6 AMK78219.1 - 0.064 14.0 7.6 0.11 13.3 7.6 1.4 1 0 0 1 1 1 0 KIAA1430 homologue DUF1515 PF07439.11 AMK78219.1 - 0.084 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Atg14 PF10186.9 AMK78219.1 - 0.095 11.8 8.6 0.13 11.3 8.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 AMK78219.1 - 0.096 12.0 12.6 0.18 11.1 12.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sigma70_ner PF04546.13 AMK78219.1 - 0.17 11.7 6.6 0.23 11.3 6.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SH3_6 PF12913.7 AMK78219.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) KASH_CCD PF14662.6 AMK78219.1 - 0.24 11.2 14.4 0.38 10.6 14.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 AMK78219.1 - 0.32 10.6 18.8 1 9.0 18.8 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 AMK78219.1 - 0.35 11.1 11.9 0.55 10.5 11.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.18 AMK78219.1 - 0.5 10.7 7.8 7.5 6.9 0.2 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family V-SNARE PF05008.15 AMK78219.1 - 0.58 10.6 14.1 0.63 10.5 13.0 1.6 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus DUF2935 PF11155.8 AMK78219.1 - 0.79 10.1 3.6 1.1 9.6 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF4407 PF14362.6 AMK78219.1 - 0.83 8.9 11.6 1.6 8.0 11.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5094 PF17015.5 AMK78219.1 - 0.97 9.5 9.6 2.1 8.4 8.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) FUSC PF04632.12 AMK78219.1 - 0.99 7.9 4.4 1.2 7.6 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mto2_bdg PF12808.7 AMK78219.1 - 1.1 9.6 14.3 0.65 10.3 2.0 3.0 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FapA PF03961.13 AMK78219.1 - 1.1 7.8 6.4 1.4 7.4 6.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 AMK78219.1 - 1.1 7.7 6.7 1.5 7.3 6.7 1.1 1 0 0 1 1 1 0 Macoilin family FAP206 PF12018.8 AMK78219.1 - 1.6 8.2 7.0 2.2 7.7 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function NBP1 PF08537.10 AMK78219.1 - 1.7 7.9 9.0 2.4 7.5 9.0 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 APG6_N PF17675.1 AMK78219.1 - 1.9 9.0 20.8 7.4 7.1 20.7 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 AMK78219.1 - 2.2 8.8 22.5 6.4 7.3 10.5 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 AMK78219.1 - 4.9 6.4 16.8 7.3 5.8 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HALZ PF02183.18 AMK78219.1 - 5.7 7.3 12.6 7.2 6.9 1.6 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper OmpH PF03938.14 AMK78219.1 - 6 7.2 17.7 13 6.2 16.6 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 AMK78219.1 - 6.4 5.6 14.7 11 4.8 14.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 AMK78219.1 - 6.7 4.5 5.8 9.5 4.0 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFP_35_N PF07334.13 AMK78219.1 - 10 6.3 17.2 0.89 9.7 4.9 3.2 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus OTCace PF00185.24 AMK78220.1 - 3e-52 176.9 0.1 8.6e-52 175.4 0.1 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AMK78220.1 - 2.3e-48 164.0 0.0 4e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminotran_3 PF00202.21 AMK78221.1 - 1.1e-117 393.1 0.2 1.4e-117 392.8 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 AMK78221.1 - 3e-06 26.7 0.4 8.2e-06 25.3 0.4 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AMK78221.1 - 0.0016 17.7 0.1 0.0045 16.2 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Dak2 PF02734.17 AMK78223.1 - 4.3e-46 157.0 6.5 4.3e-46 157.0 6.5 1.4 2 0 0 2 2 2 1 DAK2 domain Dak1 PF02733.17 AMK78224.1 - 9.2e-121 402.5 0.3 1e-120 402.3 0.3 1.0 1 0 0 1 1 1 1 Dak1 domain Hydrolase_6 PF13344.6 AMK78225.1 - 5.6e-24 84.2 0.0 8.7e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AMK78225.1 - 4.3e-20 71.6 0.0 2.1e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 AMK78225.1 - 3.3e-08 34.1 0.0 1.2e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AMK78225.1 - 7.6e-06 26.1 0.1 0.00016 21.9 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 AMK78225.1 - 0.055 13.2 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF150 PF02576.17 AMK78226.1 - 1.5e-28 99.0 0.0 2.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 AMK78226.1 - 2.4e-15 56.4 0.0 3.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain Vault_4 PF17796.1 AMK78226.1 - 0.046 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain NusA_N PF08529.11 AMK78227.1 - 3.1e-35 121.2 2.4 3.1e-35 121.2 2.4 2.2 2 0 0 2 2 2 1 NusA N-terminal domain KH_5 PF13184.6 AMK78227.1 - 4e-27 94.1 0.2 5.6e-26 90.4 0.1 2.7 2 0 0 2 2 2 1 NusA-like KH domain HHH_5 PF14520.6 AMK78227.1 - 1.3e-12 48.1 2.8 5.6e-08 33.3 0.6 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix domain S1 PF00575.23 AMK78227.1 - 1.4e-05 25.4 0.1 1.4e-05 25.4 0.1 2.5 3 0 0 3 3 3 1 S1 RNA binding domain KH_2 PF07650.17 AMK78227.1 - 0.013 15.3 3.1 0.16 11.8 0.0 3.5 3 1 0 3 3 3 0 KH domain DUF4332 PF14229.6 AMK78227.1 - 0.019 15.2 0.7 0.76 10.0 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4332) KH_1 PF00013.29 AMK78227.1 - 0.11 12.4 0.1 43 4.0 0.0 3.4 3 0 0 3 3 3 0 KH domain RPAP1_N PF08621.10 AMK78227.1 - 0.67 9.8 4.6 6.1 6.7 0.0 3.3 3 0 0 3 3 3 0 RPAP1-like, N-terminal Nit_Regul_Hom PF10126.9 AMK78227.1 - 0.83 9.7 3.0 5.2 7.1 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII GTP_EFTU PF00009.27 AMK78228.1 - 8.7e-34 116.8 9.0 1.2e-33 116.3 3.2 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AMK78228.1 - 3.3e-31 107.5 2.4 4.2e-31 107.2 0.4 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 IF2_N PF04760.15 AMK78228.1 - 9.9e-24 82.9 4.5 1.7e-15 56.6 0.8 2.8 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region IF2_assoc PF08364.11 AMK78228.1 - 3.8e-11 43.1 8.8 1.3e-10 41.4 8.8 2.0 1 0 0 1 1 1 1 Bacterial translation initiation factor IF-2 associated region MMR_HSR1 PF01926.23 AMK78228.1 - 8.7e-11 41.9 1.6 1.7e-10 41.0 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 AMK78228.1 - 3.8e-06 26.5 0.4 1.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 AMK78228.1 - 4.3e-06 27.0 3.1 0.00014 22.2 0.2 3.4 3 0 0 3 3 2 1 Elongation factor Tu domain 2 Ras PF00071.22 AMK78228.1 - 1.4e-05 24.7 0.0 5.1e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 AMK78228.1 - 2.4e-05 24.3 0.4 0.0069 16.3 0.0 2.8 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 AMK78228.1 - 0.00035 20.1 0.1 0.0019 17.8 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 AMK78228.1 - 0.0032 16.5 4.5 0.0097 14.9 0.5 2.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 AMK78228.1 - 0.021 14.3 0.1 0.021 14.3 0.1 3.3 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Roc PF08477.13 AMK78228.1 - 0.023 14.9 0.0 0.061 13.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AMK78228.1 - 0.025 15.1 7.6 18 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain HNOBA PF07701.14 AMK78228.1 - 4.5 6.6 6.2 24 4.3 5.4 2.5 1 1 0 1 1 1 0 Heme NO binding associated RBFA PF02033.18 AMK78229.1 - 1.4e-30 105.8 1.0 1.7e-30 105.6 1.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A TruB_N PF01509.18 AMK78230.1 - 3.1e-59 199.6 0.0 8.3e-59 198.2 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AMK78230.1 - 1.9e-14 53.6 0.1 4.2e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 AMK78230.1 - 3.1e-12 46.3 0.1 6.1e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Pseudouridine synthase II TruB, C-terminal YajC PF02699.15 AMK78230.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Ribosomal_S15 PF00312.22 AMK78231.1 - 5.4e-36 122.7 1.6 6.2e-36 122.5 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RNase_PH PF01138.21 AMK78232.1 - 4.3e-43 147.0 0.0 1.3e-20 74.3 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 S1 PF00575.23 AMK78232.1 - 9.1e-20 70.8 6.6 1e-19 70.6 4.1 2.3 2 0 0 2 2 2 1 S1 RNA binding domain RNase_PH_C PF03725.15 AMK78232.1 - 2.4e-16 59.5 1.2 9.1e-07 28.8 0.5 2.9 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.14 AMK78232.1 - 8e-16 58.3 5.1 1.2e-15 57.8 3.1 2.3 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.29 AMK78232.1 - 2.1e-11 43.5 1.9 4.8e-09 35.9 1.3 2.8 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 AMK78232.1 - 0.0094 15.8 0.3 0.0094 15.8 0.3 2.4 2 1 0 2 2 2 1 KH domain S1_2 PF13509.6 AMK78232.1 - 0.055 13.5 0.1 0.26 11.4 0.1 2.3 1 1 0 1 1 1 0 S1 domain PCB_OB PF17092.5 AMK78232.1 - 0.53 11.0 2.3 2 9.2 0.3 2.6 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain TPP_enzyme_N PF02776.18 AMK78233.1 - 9.1e-38 129.6 0.0 2.3e-37 128.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 AMK78233.1 - 9.7e-26 90.4 0.2 4.7e-25 88.2 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 AMK78233.1 - 1.4e-22 79.9 0.3 7.1e-22 77.6 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 AMK78233.1 - 0.097 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Acetyltransf_10 PF13673.7 AMK78234.1 - 4.9e-17 62.0 0.0 8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AMK78234.1 - 4.3e-11 43.1 0.0 8.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK78234.1 - 1.2e-10 41.7 0.0 2.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 AMK78234.1 - 0.00026 21.6 0.4 0.0051 17.5 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AMK78234.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 AMK78234.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 AMK78234.1 - 0.039 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OmpA PF00691.20 AMK78235.1 - 1.7e-18 66.8 0.0 3.2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 OmpA family OMP_b-brl PF13505.6 AMK78235.1 - 2.3e-12 47.4 7.2 4e-12 46.6 7.2 1.4 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpW PF03922.14 AMK78235.1 - 0.042 13.7 0.2 0.15 11.9 0.2 1.8 1 1 0 1 1 1 0 OmpW family TSP_3 PF02412.18 AMK78235.1 - 7.1 6.4 13.1 0.21 11.3 6.9 1.6 2 0 0 2 2 2 0 Thrombospondin type 3 repeat UDG PF03167.19 AMK78236.1 - 6.3e-31 107.5 0.0 7.3e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4918 PF16265.5 AMK78236.1 - 0.037 13.6 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) UvrC_HhH_N PF08459.11 AMK78237.1 - 1.3e-50 171.3 0.0 3e-50 170.1 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 AMK78237.1 - 1.5e-12 47.6 0.0 4.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 AMK78237.1 - 6.3e-08 32.1 1.6 1.5e-07 30.9 1.6 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_5 PF14520.6 AMK78237.1 - 1.3e-06 28.9 0.0 3.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 AMK78237.1 - 2.6e-06 27.4 0.0 5.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_3 PF12836.7 AMK78237.1 - 0.014 15.7 0.2 5.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH PF00633.23 AMK78237.1 - 0.017 14.9 0.1 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif CDP-OH_P_transf PF01066.21 AMK78238.1 - 7.5e-16 58.7 1.6 7.5e-16 58.7 1.6 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TetR_N PF00440.23 AMK78239.1 - 2.1e-09 37.0 0.3 3.9e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 AMK78239.1 - 0.0008 19.5 0.1 0.0033 17.5 0.0 2.0 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 AMK78239.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain RasGAP PF00616.19 AMK78239.1 - 0.029 14.1 2.7 2.5 7.8 0.3 2.5 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase TetR_C_24 PF17932.1 AMK78239.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_9 PF14514.6 AMK78239.1 - 0.059 13.5 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 AMK78239.1 - 0.067 13.5 0.0 0.49 10.7 0.0 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Neuropeptide_S PF14993.6 AMK78239.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Neuropeptide S precursor protein UDPG_MGDP_dh_N PF03721.14 AMK78240.1 - 1.5e-35 122.4 0.0 7.2e-35 120.3 0.0 2.1 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 AMK78240.1 - 8.6e-24 84.0 0.1 2.4e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 AMK78240.1 - 2e-23 82.4 0.0 3.7e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 AMK78240.1 - 3e-06 27.5 0.0 0.00016 21.9 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 AMK78240.1 - 0.061 13.6 1.7 5.3 7.3 0.0 3.3 3 0 0 3 3 3 0 TrkA-N domain EPOP PF15223.6 AMK78240.1 - 0.27 10.5 0.0 0.4 10.0 0.0 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein Epimerase PF01370.21 AMK78241.1 - 1.2e-55 188.6 0.0 1.4e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK78241.1 - 1.5e-54 185.6 0.0 2.2e-54 185.1 0.0 1.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 AMK78241.1 - 1.7e-17 63.4 0.0 2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 AMK78241.1 - 9.2e-17 61.1 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AMK78241.1 - 8.3e-13 48.1 0.0 4.4e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AMK78241.1 - 5.7e-05 22.4 1.1 0.083 12.0 0.1 2.3 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 AMK78241.1 - 0.00019 21.0 0.1 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 AMK78241.1 - 0.00048 20.1 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AMK78241.1 - 0.0077 16.2 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 AMK78241.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 AMK78241.1 - 0.09 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sulfatase PF00884.23 AMK78242.1 - 4e-28 98.7 0.0 5.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 AMK78242.1 - 0.00031 20.5 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 AMK78242.1 - 0.002 18.3 0.7 0.0064 16.7 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 AMK78242.1 - 0.0029 17.0 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 AMK78242.1 - 0.0083 14.8 0.0 0.013 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 AMK78242.1 - 0.034 14.0 0.4 0.24 11.3 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function Wzy_C PF04932.15 AMK78243.1 - 1.1e-08 34.9 2.6 1.1e-08 34.9 2.6 3.6 1 1 2 3 3 3 2 O-Antigen ligase Glycos_transf_2 PF00535.26 AMK78244.1 - 8.8e-24 84.2 0.0 1.3e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK78244.1 - 1.5e-16 61.0 0.0 3e-16 60.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK78244.1 - 2.4e-05 24.7 0.0 8.3e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK78244.1 - 0.00012 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Polysacc_deac_1 PF01522.21 AMK78245.1 - 1.6e-28 99.1 0.0 2.7e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Rrf2 PF02082.20 AMK78246.1 - 5.5e-19 68.3 0.7 5.5e-19 68.3 0.7 1.5 2 0 0 2 2 2 1 Transcriptional regulator HTH_5 PF01022.20 AMK78246.1 - 5.4e-06 26.2 0.1 9.8e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AMK78246.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 AMK78246.1 - 0.00047 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AMK78246.1 - 0.00058 19.6 0.2 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain RepL PF05732.11 AMK78246.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) MarR_2 PF12802.7 AMK78246.1 - 0.0013 18.6 0.2 0.0056 16.6 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AMK78246.1 - 0.003 17.5 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 AMK78246.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 AMK78246.1 - 0.009 16.2 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HrcA_DNA-bdg PF03444.15 AMK78246.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_20 PF12840.7 AMK78246.1 - 0.017 15.1 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 AMK78246.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain WIYLD PF10440.9 AMK78246.1 - 0.059 13.2 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain HTH_3 PF01381.22 AMK78246.1 - 0.072 13.2 0.1 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_23 PF13384.6 AMK78246.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF4423 PF14394.6 AMK78246.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_47 PF16221.5 AMK78246.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix UPF0051 PF01458.17 AMK78247.1 - 1.9e-69 233.7 0.2 2.4e-69 233.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.27 AMK78248.1 - 1.2e-21 77.7 0.0 1.6e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AMK78248.1 - 4.5e-06 26.3 0.5 0.042 13.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK78248.1 - 0.0002 21.3 0.4 0.13 12.0 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK78248.1 - 0.00057 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AMK78248.1 - 0.0044 17.5 0.1 0.0066 17.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AMK78248.1 - 0.0047 16.8 0.1 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase Cytidylate_kin PF02224.18 AMK78248.1 - 0.01 15.6 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_27 PF13514.6 AMK78248.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AMK78248.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AMK78248.1 - 0.022 15.3 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AMK78248.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Glyco_trans_4_2 PF13477.6 AMK78248.1 - 0.038 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like AAA_33 PF13671.6 AMK78248.1 - 0.047 13.9 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 AMK78248.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_25 PF13481.6 AMK78248.1 - 0.098 12.2 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AMK78248.1 - 0.14 12.4 0.2 0.26 11.5 0.1 1.6 2 0 0 2 2 1 0 AAA domain Ploopntkinase1 PF18748.1 AMK78248.1 - 0.15 11.6 0.0 0.65 9.5 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA PF00004.29 AMK78248.1 - 0.19 12.1 0.9 1.9 8.9 0.9 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0051 PF01458.17 AMK78249.1 - 6.1e-71 238.6 0.7 8.9e-71 238.0 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Uma2 PF05685.12 AMK78250.1 - 1.9e-31 108.9 0.0 2.2e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease Aminotran_5 PF00266.19 AMK78251.1 - 5.5e-149 496.1 2.1 6.3e-149 496.0 2.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AMK78251.1 - 7.7e-07 28.0 0.2 5.6e-06 25.1 0.1 2.0 1 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AMK78251.1 - 2.4e-06 27.0 0.1 3.5e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AMK78251.1 - 5.2e-05 22.7 0.4 6.9e-05 22.3 0.4 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AMK78251.1 - 0.00015 21.2 0.7 0.00021 20.7 0.7 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family NifU_N PF01592.16 AMK78252.1 - 4e-25 88.4 0.0 6.5e-25 87.7 0.0 1.3 1 1 1 2 2 2 1 NifU-like N terminal domain SAM_MT PF04445.13 AMK78253.1 - 1.7e-50 171.6 0.0 2.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Rieske PF00355.26 AMK78254.1 - 1.5e-19 69.7 0.2 1.7e-19 69.5 0.2 1.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 AMK78254.1 - 1.7e-13 50.4 0.1 2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain PepSY_2 PF13670.6 AMK78254.1 - 0.11 12.5 0.2 0.23 11.5 0.2 1.5 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain LGT PF01790.18 AMK78255.1 - 1.5e-72 243.7 9.6 1.7e-72 243.6 9.6 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DUF4181 PF13789.6 AMK78255.1 - 0.44 10.8 3.1 7.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF3792 PF12670.7 AMK78255.1 - 1.4 9.1 6.5 0.59 10.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) PCRF PF03462.18 AMK78256.1 - 4.8e-55 186.4 1.5 6.8e-55 185.9 0.2 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AMK78256.1 - 1e-38 131.9 1.5 1e-38 131.8 0.2 1.7 2 0 0 2 2 2 1 RF-1 domain DUF2408 PF10303.9 AMK78256.1 - 0.03 14.9 1.0 1 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) tRNA-synt_2 PF00152.20 AMK78257.1 - 1.4e-80 270.8 1.0 1.7e-80 270.5 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AMK78257.1 - 8e-15 54.6 0.1 1.7e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AMK78257.1 - 0.00021 20.9 0.1 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Flavin_Reduct PF01613.18 AMK78258.1 - 8e-41 139.7 0.1 9.1e-41 139.5 0.1 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Nif11 PF07862.11 AMK78259.1 - 6.1e-13 48.9 0.4 6.1e-13 48.9 0.4 1.6 2 0 0 2 2 2 1 Nif11 domain Pterin_bind PF00809.22 AMK78260.1 - 1.3e-86 290.3 0.4 1.5e-86 290.1 0.4 1.0 1 0 0 1 1 1 1 Pterin binding enzyme NanE PF04131.14 AMK78260.1 - 0.044 13.0 1.6 1.1 8.4 0.3 2.4 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase CAT_RBD PF03123.15 AMK78260.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 CAT RNA binding domain PALP PF00291.25 AMK78261.1 - 5.3e-20 72.0 0.0 2e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YolD PF08863.10 AMK78261.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 YolD-like protein Dodecin PF07311.12 AMK78263.1 - 7e-28 96.7 0.2 7.6e-28 96.6 0.2 1.0 1 0 0 1 1 1 1 Dodecin TMP-TENI PF02581.17 AMK78264.1 - 8.2e-54 181.7 0.1 9.5e-54 181.5 0.1 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase NMO PF03060.15 AMK78264.1 - 0.29 10.5 6.9 0.062 12.7 0.8 2.3 2 1 0 3 3 3 0 Nitronate monooxygenase Phos_pyr_kin PF08543.12 AMK78265.1 - 2e-67 227.2 0.0 2.3e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 AMK78265.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Thi4 PF01946.17 AMK78265.1 - 0.073 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DNA_ligase_aden PF01653.18 AMK78266.1 - 1.9e-22 79.8 0.7 4.2e-14 52.4 0.1 2.6 2 1 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AMK78266.1 - 3.6e-17 62.0 0.1 7.5e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_5 PF14520.6 AMK78266.1 - 4.6e-11 43.2 0.6 5.1e-06 27.0 0.0 3.4 4 0 0 4 4 4 2 Helix-hairpin-helix domain BRCT PF00533.26 AMK78266.1 - 4.1e-10 39.9 0.0 9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 AMK78266.1 - 0.0099 15.9 1.7 0.032 14.3 1.7 1.9 1 1 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain DNA_pol_lambd_f PF10391.9 AMK78266.1 - 0.054 13.3 0.0 1.3 8.9 0.0 2.5 1 1 0 2 2 2 0 Fingers domain of DNA polymerase lambda FUR PF01475.19 AMK78267.1 - 3.9e-12 46.4 0.1 2.6e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Ferric uptake regulator family CtsR_C PF17727.1 AMK78267.1 - 0.021 14.9 0.0 4.7 7.4 0.0 2.5 1 1 1 2 2 2 0 CtsR C-terminal dimerization domain MarR PF01047.22 AMK78267.1 - 0.028 14.3 0.0 0.25 11.3 0.0 2.5 2 1 0 2 2 2 0 MarR family Penicillinase_R PF03965.16 AMK78267.1 - 0.038 14.3 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor PadR PF03551.14 AMK78267.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family RTP PF02334.16 AMK78267.1 - 0.14 12.8 0.0 0.79 10.4 0.0 2.0 2 0 0 2 2 2 0 Replication terminator protein GGDEF PF00990.21 AMK78268.1 - 3.1e-49 166.8 0.0 5.2e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF3365 PF11845.8 AMK78268.1 - 8.7e-30 104.1 0.0 4.4e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3365) DUF3667 PF12412.8 AMK78268.1 - 0.0063 16.0 0.1 0.036 13.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3667) GGDEF_2 PF17853.1 AMK78268.1 - 0.011 16.0 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 GGDEF-like domain PEP-utilizers_C PF02896.18 AMK78269.1 - 3.5e-87 292.2 0.0 6.8e-87 291.3 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 AMK78269.1 - 7.3e-53 179.9 0.0 3.3e-31 108.8 0.0 3.3 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 AMK78269.1 - 4.1e-25 87.3 0.7 1e-24 86.0 0.7 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 AMK78269.1 - 0.023 13.8 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HI0933_like PF03486.14 AMK78270.1 - 2.1e-151 504.3 0.0 2.4e-151 504.1 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AMK78270.1 - 1.8e-14 53.7 0.1 3.7e-09 36.2 0.4 3.1 2 1 1 3 3 3 3 FAD binding domain DAO PF01266.24 AMK78270.1 - 2.3e-11 43.9 0.2 1.6e-05 24.7 0.2 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AMK78270.1 - 2.7e-09 36.9 0.0 5.3e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AMK78270.1 - 4.4e-09 36.0 0.1 0.0004 19.7 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AMK78270.1 - 4.4e-08 33.2 0.4 1e-07 32.1 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 AMK78270.1 - 7.9e-08 32.0 0.1 0.0017 17.7 0.0 3.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 AMK78270.1 - 1.1e-07 31.4 0.9 0.0003 20.1 0.2 2.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK78270.1 - 3.4e-07 30.7 0.1 0.00025 21.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 AMK78270.1 - 1.5e-05 25.0 0.0 5.3e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 AMK78270.1 - 4.4e-05 22.8 0.1 7.5e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 AMK78270.1 - 4.5e-05 22.7 1.9 0.00087 18.5 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 AMK78270.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AMK78270.1 - 0.0016 17.6 0.0 0.087 11.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Flavodoxin_1 PF00258.25 AMK78271.1 - 1.1e-20 74.4 0.0 1.2e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 AMK78271.1 - 0.01 16.0 0.0 0.039 14.2 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin domain Citrate_synt PF00285.21 AMK78272.1 - 1.3e-134 448.8 0.0 1.5e-134 448.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain RBM1CTR PF08081.11 AMK78272.1 - 0.057 13.5 1.0 0.11 12.6 1.0 1.4 1 0 0 1 1 1 0 RBM1CTR (NUC064) family Sdh_cyt PF01127.22 AMK78273.1 - 2.7e-26 92.0 8.1 3.1e-26 91.8 8.1 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 AMK78273.1 - 0.0026 17.9 7.1 0.0033 17.5 7.1 1.2 1 0 0 1 1 1 1 Fumarate reductase subunit D LptF_LptG PF03739.14 AMK78273.1 - 0.52 9.1 8.4 0.8 8.5 8.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Sdh_cyt PF01127.22 AMK78274.1 - 5e-15 55.6 7.9 6.2e-15 55.3 7.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.12 AMK78274.1 - 8e-06 25.6 3.7 4.8e-05 23.1 3.7 1.9 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit FAD_binding_2 PF00890.24 AMK78275.1 - 1.2e-120 403.5 5.7 1.5e-120 403.1 5.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AMK78275.1 - 3.7e-43 146.6 0.3 5.5e-43 146.0 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AMK78275.1 - 0.00022 20.6 0.1 0.00039 19.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AMK78275.1 - 0.00079 18.7 0.2 0.0087 15.3 0.1 2.4 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 AMK78275.1 - 0.0078 15.3 2.0 0.26 10.3 2.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 AMK78275.1 - 0.083 12.5 1.3 2.4 7.7 1.2 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Fer2_3 PF13085.6 AMK78276.1 - 7.1e-35 119.3 0.2 1.6e-34 118.2 0.0 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 AMK78276.1 - 1.5e-08 35.0 4.8 1.5e-08 35.0 4.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AMK78276.1 - 4.5e-08 33.1 2.3 4.5e-08 33.1 2.3 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AMK78276.1 - 5.1e-08 33.2 11.8 1.6e-07 31.7 8.1 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AMK78276.1 - 0.00094 19.7 15.5 0.026 15.1 7.7 3.2 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer2 PF00111.27 AMK78276.1 - 0.0012 18.7 3.5 0.0027 17.6 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 AMK78276.1 - 0.67 10.2 16.5 0.06 13.5 8.0 2.9 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 AMK78276.1 - 8.4 7.4 14.7 17 6.4 10.6 3.0 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain Sdh5 PF03937.16 AMK78277.1 - 3.7e-18 65.2 3.5 4.1e-18 65.1 3.5 1.0 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Queuosine_synth PF02547.15 AMK78278.1 - 2.7e-130 434.2 0.0 3.1e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein ComP_DUS PF16732.5 AMK78279.1 - 4.4e-18 66.0 0.0 7.8e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Type IV minor pilin ComP, DNA uptake sequence receptor N_methyl PF07963.12 AMK78279.1 - 7.4e-08 31.6 3.1 1.4e-07 30.8 3.1 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Neisseria_PilC PF05567.11 AMK78280.1 - 1.6e-68 231.4 1.7 3.1e-68 230.5 1.7 1.5 1 0 0 1 1 1 1 Neisseria PilC beta-propeller domain PQQ_3 PF13570.6 AMK78280.1 - 0.27 11.8 0.0 0.27 11.8 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain PilX_N PF14341.6 AMK78281.1 - 7.8e-17 61.0 3.1 1.6e-16 60.0 3.1 1.6 1 0 0 1 1 1 1 PilX N-terminal PilX PF13681.6 AMK78281.1 - 8e-14 51.8 4.2 3.5e-13 49.7 4.2 2.0 1 1 0 1 1 1 1 Type IV pilus assembly protein PilX C-term SHR3_chaperone PF08229.11 AMK78281.1 - 0.11 11.5 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 PilW PF16074.5 AMK78282.1 - 1e-19 70.8 0.8 1.5e-19 70.3 0.5 1.4 1 1 0 1 1 1 1 Type IV Pilus-assembly protein W N_methyl PF07963.12 AMK78282.1 - 7.4e-07 28.5 4.7 1.3e-06 27.7 4.7 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif MRJP PF03022.16 AMK78282.1 - 0.00085 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein GutM PF06923.11 AMK78282.1 - 0.08 13.0 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) N_methyl PF07963.12 AMK78283.1 - 5.5e-08 32.0 4.7 8.5e-08 31.4 4.7 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 AMK78284.1 - 3.1e-23 82.3 0.9 4.1e-23 81.9 0.9 1.1 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AMK78284.1 - 4.2e-09 35.6 0.6 7.1e-09 34.8 0.6 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Response_reg PF00072.24 AMK78285.1 - 9.5e-28 96.6 0.1 1.1e-27 96.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheW PF01584.19 AMK78286.1 - 1.2e-23 83.3 0.4 2.2e-23 82.4 0.4 1.4 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AMK78286.1 - 2.6e-20 72.5 0.1 9.4e-20 70.7 0.0 2.1 2 0 0 2 2 2 1 Hpt domain H-kinase_dim PF02895.14 AMK78286.1 - 9.9e-19 67.5 2.5 2.3e-18 66.3 2.5 1.7 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.26 AMK78286.1 - 2.1e-18 66.9 0.0 6.2e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK78286.1 - 0.003 17.5 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AMK78286.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CheW PF01584.19 AMK78287.1 - 5.7e-36 123.2 0.8 7.2e-36 122.9 0.8 1.1 1 0 0 1 1 1 1 CheW-like domain RNA_pol_A_CTD PF03118.15 AMK78287.1 - 0.059 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain MCPsignal PF00015.21 AMK78288.1 - 5.6e-52 176.0 23.1 5.6e-52 176.0 23.1 3.6 2 1 2 4 4 4 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 AMK78288.1 - 2.6e-19 69.3 0.0 7.3e-18 64.6 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AMK78288.1 - 1.5e-18 66.9 0.1 7.8e-13 48.6 0.0 3.4 2 1 0 2 2 2 2 PAS domain PAS PF00989.25 AMK78288.1 - 1.9e-13 50.4 0.0 5.5e-09 36.0 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AMK78288.1 - 4.7e-11 42.9 0.0 0.00062 20.0 0.0 3.9 2 1 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AMK78288.1 - 1.6e-10 40.7 0.3 0.00036 20.5 0.1 4.3 4 0 0 4 4 4 2 PAS domain HAMP PF00672.25 AMK78288.1 - 0.00054 20.3 0.8 9.6 6.7 0.0 4.9 5 0 0 5 5 4 1 HAMP domain EcoEI_R_C PF08463.10 AMK78288.1 - 0.062 13.4 2.7 0.1 12.7 0.5 2.3 2 1 0 2 2 2 0 EcoEI R protein C-terminal DUF4379 PF14311.6 AMK78288.1 - 0.09 13.2 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain ArsP_1 PF03773.13 AMK78288.1 - 0.13 11.4 1.4 0.25 10.4 1.4 1.4 1 0 0 1 1 1 0 Predicted permease PAS_7 PF12860.7 AMK78288.1 - 0.24 11.6 0.1 0.24 11.6 0.1 3.7 3 1 2 5 5 5 0 PAS fold Rootletin PF15035.6 AMK78288.1 - 0.71 9.9 9.2 0.34 10.9 0.6 2.9 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Golgin_A5 PF09787.9 AMK78288.1 - 2.4 7.6 16.8 0.19 11.2 1.8 3.0 2 1 0 2 2 2 0 Golgin subfamily A member 5 Goodbye PF17109.5 AMK78288.1 - 2.8 8.4 9.9 13 6.2 0.1 4.1 3 2 1 4 4 4 0 fungal STAND N-terminal Goodbye domain CheW PF01584.19 AMK78289.1 - 1.5e-33 115.3 0.3 1.7e-33 115.2 0.3 1.0 1 0 0 1 1 1 1 CheW-like domain AAA_31 PF13614.6 AMK78290.1 - 8.2e-44 149.6 0.0 1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AMK78290.1 - 1.5e-18 67.1 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 AMK78290.1 - 4.7e-17 62.3 0.0 8e-17 61.5 0.0 1.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 AMK78290.1 - 2.6e-13 49.9 0.2 1.5e-06 27.7 0.2 2.1 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 AMK78290.1 - 3.6e-11 43.0 0.0 6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 AMK78290.1 - 4.1e-09 36.3 0.0 2.8e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 AMK78290.1 - 1.3e-06 27.8 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase MeaB PF03308.16 AMK78290.1 - 0.00049 19.2 0.3 0.0052 15.8 0.1 2.3 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 AMK78290.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein FTHFS PF01268.19 AMK78290.1 - 0.023 12.9 0.1 0.031 12.5 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF1611 PF07755.11 AMK78290.1 - 0.037 13.3 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain CLP1_P PF16575.5 AMK78290.1 - 0.049 13.4 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 AMK78290.1 - 0.17 11.5 0.2 0.38 10.3 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain STAS_2 PF13466.6 AMK78291.1 - 2e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain FAM104 PF15434.6 AMK78291.1 - 0.04 14.5 0.8 0.059 13.9 0.8 1.2 1 0 0 1 1 1 0 Family 104 CENP-P PF13096.6 AMK78291.1 - 0.12 12.0 0.9 0.5 10.0 0.1 2.1 2 1 0 2 2 2 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P CheR PF01739.18 AMK78292.1 - 4e-66 222.2 0.0 5.4e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AMK78292.1 - 3.1e-12 46.0 0.1 7.6e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 AMK78292.1 - 0.0012 19.5 0.0 0.17 12.6 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK78292.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78292.1 - 0.0017 19.1 0.0 0.024 15.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78292.1 - 0.013 16.1 0.1 0.22 12.2 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 AMK78292.1 - 0.063 13.1 0.1 0.85 9.4 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain DUF1729 PF08354.10 AMK78292.1 - 0.069 12.0 0.0 0.23 10.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) CheD PF03975.13 AMK78293.1 - 4.3e-29 100.8 0.0 6e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction CheB_methylest PF01339.17 AMK78294.1 - 5e-56 189.1 1.2 2.1e-55 187.1 0.6 2.0 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AMK78294.1 - 4.8e-24 84.7 0.4 5.1e-23 81.4 0.2 2.4 2 0 0 2 2 2 1 Response regulator receiver domain MCPsignal PF00015.21 AMK78295.1 - 3.6e-28 98.5 14.2 3.6e-28 98.5 14.2 1.8 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.10 AMK78295.1 - 0.016 15.4 7.2 0.18 12.0 3.7 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_hydro_45 PF02015.16 AMK78295.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 45 Baculo_PEP_C PF04513.12 AMK78295.1 - 0.12 12.5 9.7 0.23 11.5 0.2 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus STAS PF01740.21 AMK78296.1 - 7.3e-09 35.3 0.1 9.4e-09 34.9 0.1 1.2 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AMK78296.1 - 1.3e-08 35.0 0.0 1.6e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 STAS domain AI-2E_transport PF01594.16 AMK78297.1 - 2.4e-63 214.3 42.1 2.9e-63 214.0 42.1 1.0 1 0 0 1 1 1 1 AI-2E family transporter COOH-NH2_lig PF14395.6 AMK78297.1 - 0.17 11.1 0.6 0.24 10.6 0.2 1.4 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 PhoH PF02562.16 AMK78298.1 - 4.1e-52 176.6 0.0 6.3e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 AMK78298.1 - 6.8e-40 136.4 0.1 1.4e-39 135.4 0.0 1.5 2 0 0 2 2 2 1 PIN domain AAA_30 PF13604.6 AMK78298.1 - 1.2e-07 31.7 0.0 4.8e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK78298.1 - 2.8e-06 27.7 0.3 1.3e-05 25.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 AMK78298.1 - 7.3e-05 23.1 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AMK78298.1 - 0.017 14.7 0.1 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 AMK78298.1 - 0.08 12.7 0.1 3 7.6 0.0 2.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA PF00004.29 AMK78298.1 - 0.33 11.4 2.6 0.81 10.1 0.6 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Baculo_PEP_C PF04513.12 AMK78299.1 - 0.0045 17.0 0.2 0.0094 16.0 0.2 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF982 PF06169.12 AMK78299.1 - 0.033 14.2 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF982) OKR_DC_1 PF01276.20 AMK78299.1 - 0.041 12.6 0.4 0.05 12.3 0.4 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain NPV_P10 PF05531.12 AMK78299.1 - 0.056 13.9 0.7 1.3 9.6 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ResIII PF04851.15 AMK78299.1 - 0.079 13.0 0.7 0.1 12.6 0.7 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1664 PF07889.12 AMK78299.1 - 0.1 12.6 0.6 0.63 10.1 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_19 PF14559.6 AMK78300.1 - 2.1e-05 24.9 0.7 2.1e-05 24.9 0.7 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78300.1 - 0.00048 19.8 0.0 0.00079 19.1 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 AMK78300.1 - 0.0005 20.7 7.5 0.0081 16.8 0.6 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78300.1 - 0.00051 20.0 0.1 2.4 8.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 AMK78300.1 - 0.014 15.7 0.5 0.12 12.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78300.1 - 0.022 15.6 1.3 0.089 13.7 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 AMK78300.1 - 0.03 14.5 0.7 1 9.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 AMK78300.1 - 0.13 12.6 1.8 2.4 8.5 1.7 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 AMK78300.1 - 0.34 11.7 3.2 37 5.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 AMK78301.1 - 2.1e-35 122.4 0.0 3.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 AMK78301.1 - 3.4e-09 36.7 0.8 1.1e-05 25.3 0.1 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 AMK78301.1 - 3.5e-06 27.1 0.0 2.8e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 AMK78301.1 - 5.5e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Glyco_tran_10_N PF17039.5 AMK78301.1 - 0.013 15.9 0.1 0.028 14.9 0.1 1.5 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal SesA PF17107.5 AMK78301.1 - 0.022 14.9 0.2 0.12 12.6 0.1 2.2 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Peptidase_M22 PF00814.25 AMK78302.1 - 3.8e-24 85.8 0.0 6.5e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family Sua5_yciO_yrdC PF01300.18 AMK78303.1 - 3e-41 140.9 0.0 3.4e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Methyltransf_4 PF02390.17 AMK78303.1 - 0.06 12.8 0.0 0.94 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Peptidase_M50 PF02163.22 AMK78304.1 - 9.6e-09 34.9 10.3 5.3e-06 25.9 1.3 3.1 2 1 0 3 3 3 3 Peptidase family M50 PepSY_TM PF03929.16 AMK78304.1 - 0.073 12.7 1.0 0.13 11.9 0.3 1.8 2 0 0 2 2 2 0 PepSY-associated TM region GPR_Gpa2_C PF11970.8 AMK78304.1 - 0.42 10.7 3.2 2.5 8.3 0.5 2.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term SMC_ScpA PF02616.14 AMK78305.1 - 2.7e-31 109.3 7.9 6.1e-31 108.2 7.9 1.5 1 1 0 1 1 1 1 Segregation and condensation protein ScpA Rad21_Rec8 PF04824.16 AMK78305.1 - 0.00015 20.9 0.2 0.0004 19.6 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpB PF04079.16 AMK78306.1 - 2.7e-53 179.9 0.0 3.4e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB DUF4777 PF16007.5 AMK78306.1 - 0.17 12.2 0.2 0.72 10.1 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4777) PseudoU_synth_2 PF00849.22 AMK78307.1 - 3.9e-14 53.0 0.0 5.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AMK78307.1 - 3.5e-12 45.8 0.7 7e-11 41.7 0.0 2.9 2 1 1 3 3 3 1 S4 domain A_deaminase PF00962.22 AMK78308.1 - 5.6e-17 62.1 0.2 1.9e-16 60.3 0.1 1.9 2 0 0 2 2 2 1 Adenosine/AMP deaminase LPAM_1 PF08139.12 AMK78308.1 - 0.24 12.0 1.1 0.59 10.7 1.1 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DNA_pol3_alpha PF07733.12 AMK78309.1 - 4.4e-87 292.0 0.0 6.4e-87 291.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AMK78309.1 - 1.5e-58 196.8 0.0 2.3e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain HHH_6 PF14579.6 AMK78309.1 - 4.9e-21 74.8 0.9 1.5e-20 73.2 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif PHP PF02811.19 AMK78309.1 - 1.8e-16 60.9 0.0 3.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 PHP domain tRNA_anti-codon PF01336.25 AMK78309.1 - 5.3e-08 32.7 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HHH_3 PF12836.7 AMK78309.1 - 0.00011 22.3 0.4 0.00067 19.9 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix motif T2SSK PF03934.13 AMK78309.1 - 2.8 7.3 7.3 2.6 7.3 0.1 3.0 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein K IMS PF00817.20 AMK78310.1 - 2.7e-08 33.9 0.0 4.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family DUF1805 PF08827.11 AMK78310.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) SulA PF03846.14 AMK78311.1 - 1.5e-06 28.1 0.4 2.4e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 Cell division inhibitor SulA RecA PF00154.21 AMK78311.1 - 0.00081 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein LexA_DNA_bind PF01726.16 AMK78312.1 - 1.5e-26 92.0 0.0 2.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 AMK78312.1 - 1.2e-11 44.4 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like FaeA PF04703.12 AMK78312.1 - 0.00029 21.2 0.0 0.00052 20.3 0.0 1.4 1 0 0 1 1 1 1 FaeA-like protein HTH_11 PF08279.12 AMK78312.1 - 0.0016 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 AMK78312.1 - 0.002 18.1 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 AMK78312.1 - 0.034 13.8 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Response_reg PF00072.24 AMK78313.1 - 3.6e-42 143.0 2.1 1.5e-23 83.1 0.4 2.0 2 0 0 2 2 2 2 Response regulator receiver domain FleQ PF06490.11 AMK78313.1 - 0.00019 21.8 0.1 0.36 11.2 0.0 2.5 2 1 0 2 2 2 2 Flagellar regulatory protein FleQ BRCT_3 PF18428.1 AMK78313.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF447 PF04289.12 AMK78314.1 - 5.2e-42 143.6 0.0 5.9e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF447) 4HFCP_synth PF04476.13 AMK78315.1 - 2.3e-68 230.4 0.3 2.5e-68 230.2 0.3 1.0 1 0 0 1 1 1 1 4-HFC-P synthase Glyco_hydro_114 PF03537.13 AMK78315.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 EAL PF00563.20 AMK78316.1 - 3.9e-70 236.1 0.1 6.2e-70 235.4 0.1 1.3 1 0 0 1 1 1 1 EAL domain MASE3 PF17159.4 AMK78316.1 - 4.1e-62 209.8 10.8 6.9e-62 209.0 10.8 1.3 1 0 0 1 1 1 1 Membrane-associated sensor domain GGDEF PF00990.21 AMK78316.1 - 1.3e-51 174.6 0.1 2.7e-51 173.5 0.1 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 AMK78316.1 - 1.3e-26 92.9 0.0 5.3e-10 39.5 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 AMK78316.1 - 4.8e-22 78.2 0.0 9.4e-11 41.9 0.1 3.5 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 AMK78316.1 - 2.5e-21 75.8 0.1 5.9e-08 32.7 0.0 4.5 4 1 0 4 4 4 3 PAS fold PAS_8 PF13188.7 AMK78316.1 - 2.4e-15 56.1 0.7 2.6e-05 24.1 0.0 4.6 4 1 0 4 4 4 2 PAS domain PAS_3 PF08447.12 AMK78316.1 - 1.7e-13 50.6 0.5 6.9e-06 26.3 0.0 4.0 4 0 0 4 4 4 2 PAS fold PAS_7 PF12860.7 AMK78316.1 - 0.081 13.1 0.0 40 4.4 0.0 3.6 3 1 0 3 3 3 0 PAS fold Mem_trans PF03547.18 AMK78317.1 - 1.1e-25 89.9 23.1 4.6e-15 54.9 10.8 2.0 1 1 1 2 2 2 2 Membrane transport protein Reoviridae_Vp9 PF08978.10 AMK78317.1 - 0.15 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 Reoviridae VP9 MoCF_biosynth PF00994.24 AMK78318.1 - 6.9e-29 100.4 0.0 1.4e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 AMK78318.1 - 3.8e-05 23.8 0.0 8.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Damage-inducible protein CinA KH domain CinA PF02464.17 AMK78318.1 - 0.011 15.3 0.2 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Competence-damaged protein ABC_tran PF00005.27 AMK78319.1 - 4.6e-55 185.9 1.0 4e-27 95.4 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_tran_CTD PF16326.5 AMK78319.1 - 6.5e-19 68.0 11.0 6.5e-19 68.0 11.0 2.7 3 0 0 3 3 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 AMK78319.1 - 3.4e-14 53.4 6.1 0.00063 19.6 0.1 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 AMK78319.1 - 9.2e-11 41.6 2.4 9.2e-11 41.6 2.4 3.1 2 1 1 3 3 3 1 ABC transporter SMC_N PF02463.19 AMK78319.1 - 2e-07 30.7 1.4 0.018 14.5 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AMK78319.1 - 1.1e-06 28.7 0.1 0.012 15.5 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 AMK78319.1 - 1.4e-06 27.9 0.3 0.019 14.7 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AMK78319.1 - 1.7e-06 28.1 0.0 0.0066 16.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 AMK78319.1 - 0.00037 20.9 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 AMK78319.1 - 0.00039 19.5 0.1 0.29 10.1 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 AMK78319.1 - 0.00076 19.9 1.2 0.041 14.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 AMK78319.1 - 0.002 18.1 0.2 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 AMK78319.1 - 0.003 18.1 19.0 0.027 15.0 8.5 4.0 2 1 2 4 4 4 1 AAA domain AAA_22 PF13401.6 AMK78319.1 - 0.0052 17.1 5.2 0.095 13.0 0.1 3.8 3 2 0 3 3 3 1 AAA domain NB-ARC PF00931.22 AMK78319.1 - 0.0071 15.6 0.0 1.6 7.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 AMK78319.1 - 0.0084 15.3 0.1 2.5 7.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Roc PF08477.13 AMK78319.1 - 0.015 15.5 0.2 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 AMK78319.1 - 0.022 15.3 0.2 7.2 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 AMK78319.1 - 0.024 15.0 0.0 17 5.9 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 AMK78319.1 - 0.026 13.4 0.1 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 AMK78319.1 - 0.041 13.9 0.6 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 AMK78319.1 - 0.056 13.5 1.4 0.47 10.5 0.0 2.7 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.6 AMK78319.1 - 0.064 13.0 0.4 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 AMK78319.1 - 0.11 12.4 0.7 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 AMK78319.1 - 0.12 12.0 0.1 9.6 5.8 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 AMK78319.1 - 0.27 11.5 3.8 16 5.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 AMK78319.1 - 0.32 10.9 1.3 18 5.2 0.3 2.9 3 0 0 3 3 2 0 NTPase AAA_15 PF13175.6 AMK78319.1 - 0.36 10.5 10.5 28 4.3 8.2 3.3 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 AMK78319.1 - 4.4 7.3 11.9 3.4 7.7 0.0 3.6 4 1 1 5 5 4 0 Helicase HerA, central domain Cgr1 PF03879.14 AMK78319.1 - 6.6 7.2 13.7 0.52 10.7 0.9 2.3 2 0 0 2 2 2 0 Cgr1 family HATPase_c PF02518.26 AMK78321.1 - 1.2e-20 74.1 0.0 3.3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AMK78321.1 - 5.5e-14 52.2 0.2 3.4e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold Hemerythrin PF01814.23 AMK78321.1 - 1.4e-13 51.6 4.0 1.4e-13 51.6 4.0 2.6 3 0 0 3 3 3 1 Hemerythrin HHE cation binding domain HisKA PF00512.25 AMK78321.1 - 9.1e-13 48.0 3.6 6.3e-12 45.3 0.4 3.4 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 AMK78321.1 - 4.1e-10 39.6 0.4 2.2e-09 37.3 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 AMK78321.1 - 0.006 16.8 0.0 0.023 14.9 0.0 2.1 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 AMK78321.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK78321.1 - 0.029 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 GHKL domain PAS_8 PF13188.7 AMK78321.1 - 0.043 13.9 0.0 0.27 11.3 0.0 2.5 1 1 1 2 2 2 0 PAS domain PAS_4 PF08448.10 AMK78321.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 PAS fold Gmx_para_CXXCG PF09535.10 AMK78321.1 - 0.13 11.5 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Response_reg PF00072.24 AMK78322.1 - 5.3e-22 78.1 0.0 4.2e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HD_5 PF13487.6 AMK78322.1 - 2.2e-15 56.7 0.4 8.1e-15 54.8 0.2 2.2 2 0 0 2 2 2 1 HD domain HD PF01966.22 AMK78322.1 - 0.012 15.9 0.0 0.046 13.9 0.0 2.0 1 0 0 1 1 1 0 HD domain HDOD PF08668.12 AMK78322.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 HDOD domain KxDL PF10241.9 AMK78322.1 - 0.068 13.4 3.9 0.2 11.9 3.9 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein Prominin PF05478.11 AMK78322.1 - 0.069 11.1 1.0 0.093 10.7 1.0 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 AMK78322.1 - 0.11 11.8 1.3 0.15 11.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-4B PF06273.11 AMK78322.1 - 0.37 9.8 3.0 0.53 9.3 3.0 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PPK2 PF03976.14 AMK78323.1 - 1.8e-96 322.1 2.5 2e-96 321.9 2.5 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) HTH_ABP1_N PF18107.1 AMK78323.1 - 0.074 12.8 3.4 0.25 11.1 0.0 2.4 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain APP_N PF02177.16 AMK78324.1 - 0.00039 20.8 0.6 0.19 12.1 0.1 2.5 2 0 0 2 2 2 2 Amyloid A4 N-terminal heparin-binding Nudix_hydro PF18290.1 AMK78324.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain T2SSG PF08334.11 AMK78324.1 - 0.11 12.5 1.4 0.12 12.5 0.2 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G EF-hand_6 PF13405.6 AMK78325.1 - 0.06 13.3 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 AMK78325.1 - 0.074 12.6 0.1 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 AMK78325.1 - 0.11 13.0 0.1 0.36 11.3 0.1 2.0 1 1 0 1 1 1 0 EF-hand domain pair Phage_holin_3_6 PF07332.11 AMK78325.1 - 4.2 7.4 8.9 8.6 6.4 8.0 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III T2SSC PF11356.8 AMK78327.1 - 2.1e-25 89.3 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Type II secretion system protein C Secretin PF00263.21 AMK78328.1 - 6.9e-48 162.5 4.1 1.4e-47 161.5 4.1 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AMK78328.1 - 6.4e-34 116.2 12.5 2.5e-14 53.4 0.4 3.9 4 0 0 4 4 4 3 Bacterial type II/III secretion system short domain T2SSE PF00437.20 AMK78329.1 - 2.7e-90 302.1 3.6 3.8e-90 301.6 3.6 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AMK78329.1 - 3.9e-06 27.2 0.0 2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK78329.1 - 3e-05 24.5 0.2 0.0003 21.2 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 AMK78329.1 - 4.7e-05 23.2 0.1 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AMK78329.1 - 9.3e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 AMK78329.1 - 0.00021 21.2 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK78329.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 AMK78329.1 - 0.003 18.1 0.0 0.0077 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AMK78329.1 - 0.0034 17.7 0.3 0.013 15.8 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 AMK78329.1 - 0.0037 17.7 0.0 0.0088 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AMK78329.1 - 0.0047 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AMK78329.1 - 0.0083 16.1 0.1 0.057 13.3 0.1 2.3 2 0 0 2 2 2 1 NTPase ResIII PF04851.15 AMK78329.1 - 0.016 15.2 0.0 0.039 13.9 0.0 1.6 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AMK78329.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 AMK78329.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AMK78329.1 - 0.019 15.5 0.1 0.091 13.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Rad17 PF03215.15 AMK78329.1 - 0.024 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DEAD PF00270.29 AMK78329.1 - 0.026 14.3 0.1 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.19 AMK78329.1 - 0.042 13.5 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 AMK78329.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 AMK78329.1 - 0.056 13.2 0.0 0.2 11.4 0.0 1.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein SMC_N PF02463.19 AMK78329.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.9 AMK78329.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 AMK78329.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 AMK78329.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 AMK78329.1 - 0.15 11.2 0.3 0.29 10.3 0.0 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) TK PF00265.18 AMK78329.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase T2SSF PF00482.23 AMK78330.1 - 5.8e-56 187.8 13.2 1.4e-28 99.3 2.8 2.4 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F DUF2062 PF09835.9 AMK78330.1 - 0.011 15.5 2.4 0.43 10.4 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Orthoreo_P10 PF07204.11 AMK78330.1 - 0.018 15.0 1.1 0.2 11.6 0.0 2.7 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 FtsX PF02687.21 AMK78330.1 - 0.15 12.5 2.8 2.9 8.4 0.6 2.5 2 0 0 2 2 2 0 FtsX-like permease family T2SSG PF08334.11 AMK78331.1 - 2e-39 134.0 0.1 2.4e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AMK78331.1 - 2e-11 42.9 1.3 2.9e-11 42.4 1.3 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 AMK78332.1 - 9.1e-09 35.7 0.0 1.3e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AMK78332.1 - 4.8e-08 32.2 4.1 1.1e-07 31.1 4.1 1.6 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSI PF02501.17 AMK78333.1 - 2.8e-14 53.0 0.1 3.7e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein I N_methyl PF07963.12 AMK78333.1 - 3.3e-08 32.7 4.9 6.9e-08 31.7 4.9 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PulG PF11773.8 AMK78333.1 - 0.11 12.3 1.2 0.14 12.0 1.2 1.1 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin ArsP_1 PF03773.13 AMK78333.1 - 0.14 11.2 0.8 0.18 10.9 0.8 1.1 1 0 0 1 1 1 0 Predicted permease T2SSJ PF11612.8 AMK78334.1 - 1.3e-33 116.2 0.3 1.6e-33 115.9 0.3 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 AMK78334.1 - 1.1e-08 34.2 3.5 1.9e-08 33.5 3.5 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSK PF03934.13 AMK78335.1 - 6.8e-75 252.0 0.6 8e-75 251.8 0.6 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 AMK78335.1 - 4.7e-10 39.6 0.0 0.00088 19.5 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix motif PilX_N PF14341.6 AMK78335.1 - 0.0037 17.2 0.9 0.01 15.8 0.9 1.8 1 0 0 1 1 1 1 PilX N-terminal T2SSL PF05134.13 AMK78336.1 - 1.8e-28 99.4 0.6 1.8e-28 99.4 0.6 1.6 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein L GspL_C PF12693.7 AMK78336.1 - 6e-23 81.4 7.6 1.3e-22 80.4 7.6 1.5 1 0 0 1 1 1 1 GspL periplasmic domain MHC2-interact PF09307.10 AMK78336.1 - 0.044 13.8 1.3 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 CLIP, MHC2 interacting YkyA PF10368.9 AMK78336.1 - 0.077 12.7 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein T2SSM PF04612.12 AMK78337.1 - 1.6e-25 90.0 1.5 1.8e-25 89.9 1.5 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M PEP-CTERM PF07589.11 AMK78338.1 - 0.0023 17.9 0.9 0.0023 17.9 0.9 2.1 2 0 0 2 2 2 1 PEP-CTERM motif Lipocalin_3 PF12702.7 AMK78338.1 - 0.0026 17.8 0.3 0.016 15.3 0.1 2.2 2 0 0 2 2 2 1 Lipocalin-like PBP_like_2 PF12849.7 AMK78339.1 - 8.1e-06 25.7 1.0 1.3e-05 25.1 1.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain ShlB PF03865.13 AMK78340.1 - 2.3e-19 70.0 1.6 3.7e-19 69.3 1.6 1.3 1 1 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 AMK78340.1 - 1.5e-16 60.0 0.1 3.1e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 POTRA domain, ShlB-type Bac_surface_Ag PF01103.23 AMK78340.1 - 4.3e-05 23.2 0.9 8.5e-05 22.2 0.5 1.5 1 1 0 1 1 1 1 Surface antigen POTRA PF07244.15 AMK78340.1 - 0.0005 20.6 0.1 0.0021 18.6 0.1 2.1 2 0 0 2 2 2 1 Surface antigen variable number repeat DUF3739 PF12545.8 AMK78341.1 - 3.6e-36 124.0 5.2 3.6e-36 124.0 5.2 7.5 9 1 0 9 9 9 1 Filamentous haemagglutinin family outer membrane protein Haemagg_act PF05860.13 AMK78341.1 - 2e-18 66.4 16.6 8e-18 64.5 4.3 5.2 5 0 0 5 5 5 2 haemagglutination activity domain FLgD_tudor PF13861.6 AMK78341.1 - 0.31 11.3 3.9 0.79 10.0 0.5 3.9 2 0 0 2 2 2 0 FlgD Tudor-like domain MotA_ExbB PF01618.16 AMK78342.1 - 1.3e-26 92.9 2.9 2.3e-26 92.0 2.9 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2341 PF10102.9 AMK78342.1 - 7.7e-15 55.3 0.0 2.2e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2341) Laminin_G_3 PF13385.6 AMK78342.1 - 5.7e-14 52.5 0.1 1.6e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Phage_holin_3_6 PF07332.11 AMK78342.1 - 0.59 10.2 9.7 12 6.0 7.9 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ABC2_membrane_5 PF13346.6 AMK78342.1 - 2.2 7.8 8.0 0.16 11.5 1.4 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein ExbD PF02472.16 AMK78343.1 - 7e-29 100.6 2.6 7.8e-29 100.5 2.6 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TonB_2 PF13103.6 AMK78344.1 - 9.1e-06 25.8 0.0 9.1e-06 25.8 0.0 2.1 2 1 0 2 2 2 1 TonB C terminal TonB_C PF03544.14 AMK78344.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal Trypan_PARP PF05887.11 AMK78344.1 - 2.9 7.9 19.2 4.3 7.3 19.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Porin_5 PF16930.5 AMK78345.1 - 1.6e-184 614.3 7.3 1.9e-184 614.1 7.3 1.0 1 0 0 1 1 1 1 Putative porin FUSC PF04632.12 AMK78346.1 - 0.023 13.2 13.3 0.028 13.0 13.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family SSB PF00436.25 AMK78346.1 - 0.052 13.6 0.3 0.096 12.7 0.3 1.5 1 0 0 1 1 1 0 Single-strand binding protein family Seryl_tRNA_N PF02403.22 AMK78346.1 - 0.15 12.3 22.1 0.036 14.3 10.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CRISPR_Cas9_WED PF18061.1 AMK78346.1 - 0.35 11.0 2.6 0.51 10.4 0.8 1.9 1 1 0 2 2 2 0 CRISPR-Cas9 WED domain Sec34 PF04136.15 AMK78346.1 - 0.41 10.5 14.2 0.15 11.9 6.9 2.5 1 1 1 2 2 2 0 Sec34-like family PIN_12 PF16289.5 AMK78346.1 - 0.51 10.8 8.8 0.73 10.3 8.4 1.5 1 1 0 1 1 1 0 PIN domain GIT_CC PF16559.5 AMK78346.1 - 0.72 9.8 11.9 0.7 9.8 4.7 3.3 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4164 PF13747.6 AMK78346.1 - 0.84 10.0 18.7 0.056 13.7 7.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DASH_Hsk3 PF08227.11 AMK78346.1 - 1.3 9.4 8.6 0.67 10.4 2.7 2.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TMF_TATA_bd PF12325.8 AMK78346.1 - 1.4 9.2 23.6 0.42 10.8 12.5 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 AMK78346.1 - 1.5 8.0 24.2 0.06 12.6 9.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.6 AMK78346.1 - 1.7 7.9 26.2 1.3 8.4 11.0 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 AMK78346.1 - 1.9 6.3 11.7 2.5 5.9 11.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.9 AMK78346.1 - 2.1 9.1 15.0 1.4 9.6 4.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc7 PF08317.11 AMK78346.1 - 2.6 6.9 27.2 2.9 6.7 26.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4472 PF14739.6 AMK78346.1 - 3.6 8.4 24.5 2.4 8.9 7.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) FlaC_arch PF05377.11 AMK78346.1 - 5.4 7.5 14.0 0.93 9.9 0.3 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 AMK78346.1 - 6.3 7.1 13.1 2.8 8.3 5.0 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Mto2_bdg PF12808.7 AMK78346.1 - 6.3 7.2 14.6 0.29 11.5 2.2 3.3 1 1 2 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4407 PF14362.6 AMK78346.1 - 7.5 5.8 21.5 12 5.1 21.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 AMK78346.1 - 8.2 6.5 13.4 5 7.2 4.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DMPK_coil PF08826.10 AMK78346.1 - 8.4 6.6 23.0 1.4 9.1 3.2 3.4 1 1 2 3 3 3 0 DMPK coiled coil domain like TMF_DNA_bd PF12329.8 AMK78346.1 - 8.9 6.4 24.7 0.25 11.4 5.6 2.9 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding LPD5 PF18799.1 AMK78346.1 - 9.4 6.6 11.6 11 6.5 0.9 2.8 1 1 2 3 3 3 0 Large polyvalent protein-associated domain 5 TPR_19 PF14559.6 AMK78347.1 - 7.4e-58 193.0 55.4 3.4e-08 33.9 3.1 13.9 5 3 11 16 16 16 14 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78347.1 - 3.1e-48 158.3 35.0 0.0016 19.1 0.0 18.6 4 3 17 21 21 20 11 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78347.1 - 1e-47 156.4 39.7 9.3e-05 22.3 0.0 19.5 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_16 PF13432.6 AMK78347.1 - 9.9e-47 157.3 26.4 4.5e-08 33.6 0.0 12.7 7 4 7 15 15 15 9 Tetratricopeptide repeat TPR_17 PF13431.6 AMK78347.1 - 1.2e-36 122.4 29.4 0.0015 18.8 0.0 16.6 17 1 0 17 17 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 AMK78347.1 - 1.1e-32 109.5 36.2 0.00086 19.3 0.2 16.0 17 0 0 17 17 15 6 Tetratricopeptide repeat TPR_1 PF00515.28 AMK78347.1 - 2.3e-31 106.3 37.5 0.00018 21.2 1.1 16.3 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78347.1 - 3e-28 97.2 32.5 2.4e-09 36.7 0.7 11.8 9 3 4 13 13 13 6 TPR repeat TPR_6 PF13174.6 AMK78347.1 - 2.1e-26 90.8 38.1 0.0043 17.6 0.0 17.8 19 0 0 19 19 19 4 Tetratricopeptide repeat TPR_12 PF13424.6 AMK78347.1 - 8.8e-25 86.8 38.7 0.00046 20.4 0.0 12.7 7 5 6 14 14 14 8 Tetratricopeptide repeat TPR_9 PF13371.6 AMK78347.1 - 4.9e-24 84.3 9.9 0.0041 17.2 0.0 9.5 9 2 1 10 10 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK78347.1 - 4.8e-20 71.6 18.0 6e-05 23.2 0.0 9.0 6 4 4 10 10 10 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 AMK78347.1 - 4.3e-17 62.2 45.4 0.041 14.2 0.1 12.0 4 2 7 12 12 12 7 Tetratricopeptide repeat TPR_7 PF13176.6 AMK78347.1 - 5.5e-16 57.4 17.0 0.033 14.2 0.4 12.8 12 2 2 14 14 13 3 Tetratricopeptide repeat TPR_15 PF13429.6 AMK78347.1 - 4.3e-12 45.8 36.6 0.075 12.2 0.9 9.2 3 2 6 10 10 10 5 Tetratricopeptide repeat TPR_21 PF09976.9 AMK78347.1 - 2.9e-11 43.4 56.0 0.00025 20.8 0.5 8.3 2 1 7 9 9 9 6 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 AMK78347.1 - 7.6e-10 38.5 18.9 0.036 13.7 0.4 7.2 3 1 2 7 7 7 4 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 AMK78347.1 - 5e-08 32.6 43.8 0.055 13.4 0.0 13.7 15 1 1 16 16 16 3 Tetratricopeptide repeat ChAPs PF09295.10 AMK78347.1 - 5.4e-07 29.0 11.7 0.0085 15.1 0.0 4.6 3 2 0 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 AMK78347.1 - 2.2e-05 24.9 13.6 0.38 11.2 0.1 6.3 5 1 2 7 7 7 1 Bacterial transcriptional activator domain NARP1 PF12569.8 AMK78347.1 - 2.2e-05 23.6 2.0 2.2e-05 23.6 2.0 6.4 2 2 2 6 6 6 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 AMK78347.1 - 3e-05 24.2 15.9 1.7 9.5 0.6 8.7 11 0 0 11 11 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 AMK78347.1 - 0.00016 21.7 16.8 4.5 7.4 0.0 8.7 9 1 1 10 10 8 1 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 AMK78347.1 - 0.00025 20.4 5.5 0.00025 20.4 5.5 4.4 1 1 1 5 5 5 1 FAT domain PknG_TPR PF16918.5 AMK78347.1 - 0.00069 18.5 16.5 0.16 10.7 0.1 4.6 3 2 2 5 5 5 3 Protein kinase G tetratricopeptide repeat Sel1 PF08238.12 AMK78347.1 - 0.036 14.8 0.0 0.51 11.1 0.0 3.2 2 0 0 2 2 1 0 Sel1 repeat Rapsyn_N PF10579.9 AMK78347.1 - 0.053 13.6 3.6 0.68 10.1 0.1 4.1 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region Alkyl_sulf_dimr PF14863.6 AMK78347.1 - 0.25 11.8 14.9 1.6 9.2 0.1 5.4 4 2 0 4 4 4 0 Alkyl sulfatase dimerisation DUF4919 PF16266.5 AMK78347.1 - 0.27 11.1 15.9 2.5 8.0 0.3 6.4 4 2 3 7 7 7 0 Domain of unknown function (DUF4919) Clathrin PF00637.20 AMK78347.1 - 0.28 11.0 15.3 0.69 9.8 0.2 4.8 5 2 1 6 6 5 0 Region in Clathrin and VPS DUF4192 PF13830.6 AMK78347.1 - 0.39 10.7 7.8 1.3 9.0 0.5 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4192) DUF4810 PF16068.5 AMK78347.1 - 0.73 10.4 15.4 11 6.7 0.1 7.2 5 3 2 7 7 7 0 Domain of unknown function (DUF4810) DUF357 PF04010.13 AMK78347.1 - 1.9 8.6 6.7 5 7.3 0.2 4.7 6 0 0 6 6 5 0 Protein of unknown function (DUF357) AAA_31 PF13614.6 AMK78348.1 - 3e-06 27.3 0.0 4.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 AMK78348.1 - 5.7e-05 22.7 0.0 7.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AMK78348.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AMK78348.1 - 0.11 12.3 0.1 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain IFT57 PF10498.9 AMK78349.1 - 2.4e-07 30.1 2.9 2.4e-07 30.1 2.9 2.7 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 Wzz PF02706.15 AMK78349.1 - 4.4e-05 23.7 2.1 4.4e-05 23.7 2.1 3.9 5 0 0 5 5 5 1 Chain length determinant protein GNVR PF13807.6 AMK78349.1 - 7.1e-05 22.7 1.7 0.0002 21.2 0.0 2.6 3 0 0 3 3 3 1 G-rich domain on putative tyrosine kinase DUF4094 PF13334.6 AMK78349.1 - 0.0088 16.4 0.5 0.0088 16.4 0.5 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4094) BrnT_toxin PF04365.13 AMK78349.1 - 0.018 15.4 0.3 3.4 8.1 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system HILPDA PF15220.6 AMK78349.1 - 0.046 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DUF4349 PF14257.6 AMK78349.1 - 1.2 8.5 0.0 1.2 8.5 0.0 4.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4349) Wzy_C PF04932.15 AMK78349.1 - 1.6 8.3 4.1 2.7 7.6 0.0 2.7 2 1 0 2 2 2 0 O-Antigen ligase Fez1 PF06818.15 AMK78349.1 - 1.7 9.1 23.3 2.7 8.4 7.6 2.7 1 1 2 3 3 3 0 Fez1 NPV_P10 PF05531.12 AMK78349.1 - 1.9 9.0 17.3 43 4.7 5.4 4.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein OMP_b-brl PF13505.6 AMK78350.1 - 9.4e-09 35.6 17.1 0.00042 20.5 5.0 3.0 2 1 1 3 3 3 2 Outer membrane protein beta-barrel domain TonB_dep_Rec PF00593.24 AMK78350.1 - 0.0002 21.3 37.4 0.0042 17.0 17.4 2.0 1 1 1 2 2 2 2 TonB dependent receptor DUF2490 PF10677.9 AMK78350.1 - 0.00091 19.2 11.0 0.15 12.0 0.3 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2490) Bac_surface_Ag PF01103.23 AMK78350.1 - 1.4 8.3 28.4 0.2 11.1 8.4 3.0 1 1 1 2 2 2 0 Surface antigen Poly_export PF02563.16 AMK78351.1 - 9.9e-22 77.0 0.1 5.5e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 AMK78351.1 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Phage-tail_3 PF13550.6 AMK78351.1 - 0.032 14.1 0.1 2 8.2 0.0 2.6 2 1 1 3 3 3 0 Putative phage tail protein DUF4096 PF13340.6 AMK78352.1 - 3.6e-24 84.8 4.8 7.4e-24 83.8 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK78353.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK78353.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK78353.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK78353.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HopJ PF08888.11 AMK78354.1 - 1.7e-45 153.8 0.0 1.8e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 HopJ type III effector protein IMPa_helical PF18642.1 AMK78354.1 - 0.067 13.6 0.0 0.088 13.2 0.0 1.3 1 1 0 1 1 1 0 Immunomodulating metalloprotease helical domain DAO PF01266.24 AMK78355.1 - 1.2e-18 67.9 0.0 1.4e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK78355.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 AMK78355.1 - 0.017 14.3 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 AMK78355.1 - 0.035 14.3 0.3 0.17 12.1 0.1 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 AMK78355.1 - 0.087 11.9 0.1 0.2 10.7 0.1 1.6 1 1 1 2 2 2 0 Lycopene cyclase protein rRNA_methylase PF06962.12 AMK78356.1 - 1.5e-39 135.1 0.0 1.9e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_31 PF13847.6 AMK78356.1 - 4.5e-07 29.8 0.0 6.4e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 AMK78356.1 - 5.1e-05 22.9 0.0 9.6e-05 22.0 0.0 1.4 2 0 0 2 2 2 1 MraW methylase family Methyltransf_25 PF13649.6 AMK78356.1 - 0.00016 22.3 0.1 0.00031 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AMK78356.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 AMK78356.1 - 0.056 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 AMK78356.1 - 0.058 13.5 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pyr_excise PF03013.14 AMK78356.1 - 0.06 13.3 0.1 6.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase Ubie_methyltran PF01209.18 AMK78356.1 - 0.082 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ppnp PF06865.11 AMK78357.1 - 2.6e-37 127.1 0.0 2.9e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase NYN PF01936.18 AMK78358.1 - 3.9e-39 134.5 0.6 4.7e-39 134.2 0.6 1.0 1 0 0 1 1 1 1 NYN domain SBP_bac_5 PF00496.22 AMK78358.1 - 0.0019 17.2 0.5 0.0033 16.4 0.4 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Peptidase_C71 PF12386.8 AMK78358.1 - 0.039 13.6 0.3 0.052 13.2 0.3 1.2 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei ANF_receptor PF01094.28 AMK78358.1 - 0.053 12.6 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region 2OG-FeII_Oxy_3 PF13640.6 AMK78358.1 - 0.12 13.3 0.0 0.14 13.0 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SmpA_OmlA PF04355.13 AMK78359.1 - 1.1e-23 82.8 0.1 1.6e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 SmpA / OmlA family DUF3192 PF11399.8 AMK78359.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) FUR PF01475.19 AMK78360.1 - 1e-45 154.8 0.4 1.1e-45 154.6 0.4 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 AMK78360.1 - 0.00026 20.9 0.5 0.00062 19.7 0.1 1.7 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain TrmB PF01978.19 AMK78360.1 - 0.0075 16.1 0.1 0.081 12.8 0.0 2.5 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 AMK78360.1 - 0.0082 16.1 0.3 0.066 13.2 0.1 2.5 2 1 1 3 3 3 1 Transcriptional regulator PadR-like family MarR PF01047.22 AMK78360.1 - 0.0084 16.0 0.1 0.22 11.5 0.0 2.8 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AMK78360.1 - 0.011 15.7 0.1 0.67 10.0 0.0 2.7 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 AMK78360.1 - 0.018 15.3 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Transposase MarR_2 PF12802.7 AMK78360.1 - 0.022 14.7 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 AMK78360.1 - 0.041 13.7 0.7 0.83 9.5 0.1 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain Alkyl_sulf_C PF14864.6 AMK78360.1 - 0.17 12.2 0.0 0.23 11.7 0.0 1.1 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal MacB_PCD PF12704.7 AMK78361.1 - 6.8e-18 65.7 0.4 6.8e-18 65.7 0.4 1.7 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 AMK78361.1 - 1.2e-09 38.5 15.2 2e-09 37.8 4.9 3.3 3 0 0 3 3 3 2 FtsX-like permease family Pho86 PF11124.8 AMK78361.1 - 0.22 10.9 2.2 1.1 8.7 1.9 2.0 1 1 0 1 1 1 0 Inorganic phosphate transporter Pho86 LysE PF01810.18 AMK78361.1 - 6.9 6.1 13.9 6.8 6.1 3.3 3.4 3 0 0 3 3 3 0 LysE type translocator Trp_oprn_chp PF09534.10 AMK78361.1 - 7 6.4 10.5 5.8 6.7 2.6 3.0 2 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ABC_tran PF00005.27 AMK78362.1 - 3.5e-32 111.8 0.1 4.6e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AMK78362.1 - 9.1e-07 28.5 0.2 0.00029 20.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK78362.1 - 5.5e-06 26.4 0.4 0.031 14.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK78362.1 - 0.0004 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 AMK78362.1 - 0.0021 18.3 0.3 0.083 13.1 0.2 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AMK78362.1 - 0.0058 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 AMK78362.1 - 0.0067 16.8 1.0 0.014 15.8 1.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 AMK78362.1 - 0.021 14.2 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 AMK78362.1 - 0.026 14.6 0.2 0.053 13.6 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 AMK78362.1 - 0.042 14.0 0.7 0.34 11.1 0.7 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AMK78362.1 - 0.054 13.2 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AMK78362.1 - 0.056 13.5 0.1 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 AMK78362.1 - 0.063 12.9 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 AMK78362.1 - 0.069 13.1 0.7 0.4 10.6 0.3 2.1 2 0 0 2 2 2 0 NACHT domain DLIC PF05783.11 AMK78362.1 - 0.073 11.9 0.1 0.098 11.5 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 AMK78362.1 - 0.085 13.1 0.2 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AMK78362.1 - 0.092 13.3 0.2 0.21 12.2 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 AMK78362.1 - 0.12 12.0 0.1 0.44 10.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain SHMT PF00464.19 AMK78366.1 - 9.3e-184 610.6 0.0 1.1e-183 610.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AMK78366.1 - 6.9e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AMK78366.1 - 1.4e-05 24.6 0.0 3.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 AMK78366.1 - 0.0022 16.8 0.0 0.0049 15.7 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 AMK78366.1 - 0.0066 15.0 0.0 0.015 13.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 AMK78366.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4147 PF13660.6 AMK78367.1 - 5.2e-79 265.0 0.2 7.6e-79 264.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 AMK78367.1 - 5.2e-36 123.1 3.6 1.1e-35 122.1 3.6 1.6 1 0 0 1 1 1 1 MOFRL family Mpt_N PF09176.11 AMK78368.1 - 1.1e-33 115.2 0.3 2.5e-33 114.0 0.3 1.6 1 0 0 1 1 1 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal AdoHcyase_NAD PF00670.21 AMK78368.1 - 0.0022 18.1 0.1 0.0037 17.3 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 AMK78368.1 - 0.0054 16.8 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 AMK78368.1 - 0.006 17.0 0.2 0.011 16.1 0.2 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.6 AMK78368.1 - 0.0096 15.8 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 AMK78368.1 - 0.021 14.2 0.1 0.05 12.9 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_C PF02866.18 AMK78369.1 - 2.3e-32 112.3 0.0 6.5e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 AMK78369.1 - 2.2e-30 105.6 0.0 3.4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ApbE PF02424.15 AMK78370.1 - 9.7e-70 235.0 0.0 1.1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 ApbE family Glycos_transf_2 PF00535.26 AMK78371.1 - 2.7e-32 111.9 0.0 4.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK78371.1 - 1.1e-15 57.9 0.0 1.8e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AMK78371.1 - 2.2e-14 53.9 0.0 1.7e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK78371.1 - 0.0049 17.3 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_49 PF13896.6 AMK78371.1 - 0.034 13.5 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Asn_synthase PF00733.21 AMK78372.1 - 1.9e-53 182.4 0.0 2.6e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 AMK78372.1 - 5.2e-45 152.3 0.0 9.4e-45 151.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AMK78372.1 - 3.8e-41 140.4 0.0 6.4e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 AMK78372.1 - 0.0066 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 AMK78372.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Glycos_transf_1 PF00534.20 AMK78373.1 - 4.1e-34 117.6 0.3 6.7e-34 116.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK78373.1 - 1.7e-20 73.8 0.0 2.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK78373.1 - 4.3e-15 56.1 0.0 2.9e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK78373.1 - 3.2e-06 27.4 0.0 7.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AMK78373.1 - 1.6e-05 25.4 0.0 0.04 14.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AMK78373.1 - 0.028 14.5 0.9 0.39 10.7 0.0 2.9 3 1 1 4 4 4 0 Glycosyl transferase 4-like Endonuc-FokI_C PF09254.11 AMK78373.1 - 0.038 13.3 0.3 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease FokI, C terminal Glycos_transf_1 PF00534.20 AMK78374.1 - 1.6e-31 109.2 0.0 1.9e-30 105.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK78374.1 - 4.9e-28 98.2 0.0 1.3e-27 96.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK78374.1 - 6.5e-09 36.0 0.0 9.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK78374.1 - 6.1e-07 29.7 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK78375.1 - 4.9e-26 91.8 0.0 8.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK78375.1 - 6.6e-13 48.5 0.0 1.8e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AMK78375.1 - 7.1e-11 42.4 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3642 PF12182.8 AMK78375.1 - 0.96 9.8 3.9 0.37 11.1 0.5 2.0 2 0 0 2 2 2 0 Bacterial lipoprotein Methyltransf_23 PF13489.6 AMK78376.1 - 8.8e-11 41.9 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78376.1 - 2.1e-09 37.9 0.0 3.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78376.1 - 9.1e-08 32.7 0.0 1.6e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78376.1 - 7.3e-07 29.9 0.0 1.5e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK78376.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 AMK78376.1 - 0.00028 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 AMK78376.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 AMK78376.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glycos_transf_2 PF00535.26 AMK78377.1 - 1.8e-21 76.7 0.1 2.5e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK78377.1 - 7.1e-14 52.2 0.0 1e-13 51.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 AMK78377.1 - 0.00019 21.0 0.2 0.00028 20.4 0.2 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 AMK78377.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AMK78377.1 - 0.029 14.9 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peripla_BP_4 PF13407.6 AMK78377.1 - 0.069 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain ABC_tran PF00005.27 AMK78378.1 - 1.7e-19 70.7 0.1 5.4e-19 69.1 0.0 1.9 2 1 0 2 2 1 1 ABC transporter Wzt_C PF14524.6 AMK78378.1 - 8.5e-13 48.5 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Wzt C-terminal domain AAA_15 PF13175.6 AMK78378.1 - 4.2e-06 26.7 0.0 7.6e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AMK78378.1 - 0.00011 21.9 0.1 0.00032 20.4 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK78378.1 - 0.0009 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 AMK78378.1 - 0.0016 19.0 0.1 0.0016 19.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AMK78378.1 - 0.002 17.9 0.4 0.007 16.1 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK78378.1 - 0.0024 18.3 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AMK78378.1 - 0.011 15.6 2.8 0.031 14.1 0.4 2.6 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK78378.1 - 0.024 14.1 0.2 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AMK78378.1 - 0.024 14.7 1.4 0.04 14.0 0.3 1.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 AMK78378.1 - 0.032 14.1 1.6 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 NTPase GTP_EFTU PF00009.27 AMK78378.1 - 0.056 13.0 0.2 0.13 11.7 0.2 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 AMK78378.1 - 0.062 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 AMK78378.1 - 0.064 13.4 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AMK78378.1 - 0.075 13.3 0.4 0.35 11.1 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AMK78378.1 - 0.081 13.2 2.3 0.68 10.2 0.1 2.9 2 1 1 3 3 3 0 AAA domain LptF_LptG PF03739.14 AMK78378.1 - 0.087 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG AAA_25 PF13481.6 AMK78378.1 - 0.087 12.4 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 AMK78378.1 - 0.089 12.4 1.6 0.11 12.1 0.4 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 AMK78378.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 AMK78378.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 AMK78378.1 - 0.12 12.1 0.1 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 AMK78378.1 - 0.12 12.4 2.0 0.72 9.9 0.1 3.1 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AMK78378.1 - 0.13 12.8 0.8 0.45 11.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 AMK78378.1 - 0.18 11.4 1.0 0.68 9.5 0.3 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 AMK78379.1 - 2.1e-16 60.0 23.9 2.1e-16 60.0 23.9 1.9 2 1 0 2 2 2 1 ABC-2 type transporter TPR_1 PF00515.28 AMK78380.1 - 1.7e-08 33.9 0.7 6.9e-05 22.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78380.1 - 8.6e-07 28.6 0.2 0.0078 16.2 0.0 3.2 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 AMK78380.1 - 2.1e-06 28.2 0.0 4.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78380.1 - 5e-05 22.9 2.9 5.6e-05 22.7 0.8 2.2 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 AMK78380.1 - 0.00015 21.7 1.0 0.01 16.0 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 AMK78380.1 - 0.00085 19.6 0.0 0.39 11.1 0.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 AMK78380.1 - 0.0011 18.8 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AMK78380.1 - 0.0012 19.5 0.0 0.016 15.9 0.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 AMK78380.1 - 0.0033 16.8 0.0 0.0085 15.5 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_17 PF13431.6 AMK78380.1 - 0.0043 17.3 0.3 0.042 14.2 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 AMK78380.1 - 0.012 15.5 0.1 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK78380.1 - 0.016 15.4 0.7 0.048 13.9 0.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 AMK78380.1 - 0.089 13.7 0.0 5.2 8.1 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 AMK78381.1 - 9.7e-31 106.6 0.0 1.3e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK78381.1 - 2.1e-23 83.2 0.0 3.9e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK78381.1 - 1.3e-13 51.3 0.3 7e-13 48.9 0.6 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK78381.1 - 8.7e-08 32.8 0.1 2.3e-07 31.4 0.1 1.8 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AMK78381.1 - 1e-07 32.2 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AMK78382.1 - 5.5e-33 114.2 0.2 8.5e-33 113.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK78382.1 - 2e-20 73.4 0.1 3.6e-20 72.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AMK78382.1 - 4.4e-16 59.5 0.0 7.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK78382.1 - 4.4e-08 33.5 0.1 9.6e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 TPR_2 PF07719.17 AMK78382.1 - 0.057 13.6 1.5 0.13 12.4 1.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TonB_dep_Rec PF00593.24 AMK78382.1 - 0.09 12.6 0.1 1.8 8.4 0.0 2.0 2 0 0 2 2 2 0 TonB dependent receptor Gamma_PGA_hydro PF05908.11 AMK78383.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase Exosortase_EpsH PF09721.10 AMK78384.1 - 3.6e-56 190.5 33.8 3.6e-56 190.5 33.8 1.7 2 0 0 2 2 2 1 Transmembrane exosortase (Exosortase_EpsH) DUF3485 PF11984.8 AMK78384.1 - 5.8e-25 88.2 0.2 9.4e-25 87.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3485) Internalin_N PF12354.8 AMK78384.1 - 0.028 14.5 2.6 0.49 10.5 0.2 3.3 4 0 0 4 4 4 0 Bacterial adhesion/invasion protein N terminal NTP_transferase PF00483.23 AMK78385.1 - 3.3e-73 246.3 0.1 9.2e-72 241.6 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 AMK78385.1 - 1.5e-69 232.7 5.9 2.8e-69 231.8 5.9 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transf_3 PF12804.7 AMK78385.1 - 1.2e-10 42.0 3.9 1.7e-09 38.2 0.2 2.9 2 1 1 3 3 3 1 MobA-like NTP transferase domain Cupin_2 PF07883.11 AMK78385.1 - 3.1e-09 36.4 1.5 5.2e-09 35.7 0.4 2.0 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 AMK78385.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain CorA PF01544.18 AMK78386.1 - 5.7e-56 190.0 1.6 8.5e-56 189.4 1.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MgtE_N PF03448.17 AMK78386.1 - 0.0013 19.3 8.1 0.0056 17.3 0.1 3.2 3 1 0 3 3 3 2 MgtE intracellular N domain DUF21 PF01595.20 AMK78387.1 - 3.9e-42 143.9 4.3 5.9e-42 143.4 4.3 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AMK78387.1 - 3.8e-17 62.1 0.9 2e-16 59.8 0.0 2.5 3 0 0 3 3 3 1 Transporter associated domain CBS PF00571.28 AMK78387.1 - 5.9e-16 58.7 0.5 9.7e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain Mannosyl_trans4 PF15971.5 AMK78387.1 - 0.094 12.6 0.8 0.19 11.6 0.8 1.4 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase Sigma54_activat PF00158.26 AMK78388.1 - 3.3e-75 251.4 0.0 5e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK78388.1 - 1.3e-25 90.2 0.0 4.2e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain FleQ PF06490.11 AMK78388.1 - 2.4e-14 53.6 0.1 1e-13 51.6 0.0 2.0 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ HTH_8 PF02954.19 AMK78388.1 - 4.8e-13 48.7 0.7 1.4e-12 47.1 0.7 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK78388.1 - 1.3e-07 31.7 0.0 6.8e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK78388.1 - 0.00059 20.3 0.0 0.0022 18.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK78388.1 - 0.00064 20.1 0.7 0.0013 19.1 0.2 2.0 2 1 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.21 AMK78388.1 - 0.011 15.2 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI HTH_50 PF18024.1 AMK78388.1 - 0.014 15.0 0.1 0.04 13.5 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TIP49 PF06068.13 AMK78388.1 - 0.022 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 AMK78388.1 - 0.025 14.3 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AMK78388.1 - 0.03 14.5 0.0 0.072 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 AMK78388.1 - 0.031 13.8 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region LSDAT_euk PF18139.1 AMK78388.1 - 0.065 12.6 0.5 0.14 11.5 0.2 1.7 2 0 0 2 2 2 0 SLOG in TRPM IstB_IS21 PF01695.17 AMK78388.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 AMK78388.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Amdase PF17645.1 AMK78388.1 - 0.073 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase HTH_30 PF13556.6 AMK78388.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Peptidase_M20 PF01546.28 AMK78389.1 - 1.6e-34 119.5 0.2 2.3e-34 118.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AMK78389.1 - 8e-12 45.0 0.1 2.4e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain MgtC PF02308.16 AMK78391.1 - 6e-33 113.8 15.0 8.5e-33 113.3 15.0 1.2 1 0 0 1 1 1 1 MgtC family Secretin PF00263.21 AMK78392.1 - 6.1e-47 159.4 7.5 1.2e-46 158.4 7.5 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 AMK78392.1 - 4.4e-21 75.1 32.8 1.2e-10 41.6 20.3 4.7 4 2 0 4 4 4 3 Bacterial type II/III secretion system short domain T2SSC PF11356.8 AMK78393.1 - 0.0035 17.2 0.1 0.0049 16.8 0.1 1.2 1 0 0 1 1 1 1 Type II secretion system protein C HofP PF10748.9 AMK78393.1 - 0.0098 15.5 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 DNA utilization proteins HofP T2SSM_b PF10741.9 AMK78394.1 - 2.1e-23 82.2 0.4 3.1e-23 81.7 0.4 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M subtype b TssO PF17561.2 AMK78394.1 - 0.066 13.3 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO IF-2 PF11987.8 AMK78394.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Translation-initiation factor 2 PilN PF05137.13 AMK78395.1 - 1.3e-09 38.1 0.1 4.4e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Fimbrial assembly protein (PilN) PilM_2 PF11104.8 AMK78395.1 - 1.1e-05 24.7 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; TSC22 PF01166.18 AMK78395.1 - 0.078 13.3 0.7 0.21 11.9 0.7 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family PRKG1_interact PF15898.5 AMK78395.1 - 0.11 13.4 0.8 0.11 13.4 0.8 1.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4988 PF16378.5 AMK78395.1 - 0.12 12.1 0.3 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function Prefoldin PF02996.17 AMK78395.1 - 5.6 6.9 6.7 11 5.9 3.4 2.5 2 1 1 3 3 3 0 Prefoldin subunit T2SSK PF03934.13 AMK78396.1 - 2.2e-34 119.1 8.7 3e-34 118.7 8.7 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 AMK78396.1 - 2.7e-06 27.5 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif PilX_N PF14341.6 AMK78396.1 - 0.069 13.1 2.6 0.17 11.9 2.6 1.7 1 0 0 1 1 1 0 PilX N-terminal N_methyl PF07963.12 AMK78397.1 - 1.7e-07 30.5 4.1 2.8e-07 29.8 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSJ PF11612.8 AMK78397.1 - 0.00016 21.9 0.0 0.00059 20.1 0.0 1.8 1 1 0 2 2 2 1 Type II secretion system (T2SS), protein J DUF641 PF04859.12 AMK78397.1 - 0.083 13.2 0.0 1.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) GST_N_5 PF18485.1 AMK78397.1 - 0.13 12.6 0.0 6 7.3 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PulG PF11773.8 AMK78397.1 - 0.24 11.2 1.3 1.6 8.7 0.3 2.2 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin N_methyl PF07963.12 AMK78398.1 - 9.8e-08 31.3 1.4 1.7e-07 30.5 1.4 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 AMK78399.1 - 1.2e-06 28.9 0.1 1.8e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Type II transport protein GspH N_methyl PF07963.12 AMK78399.1 - 1.9e-06 27.2 2.3 3.1e-06 26.5 2.3 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSG PF08334.11 AMK78400.1 - 5.1e-44 148.8 0.4 5.9e-44 148.6 0.4 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 AMK78400.1 - 1.1e-07 31.0 3.0 1.7e-07 30.5 3.0 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSF PF00482.23 AMK78401.1 - 5.2e-60 200.9 13.6 6.2e-30 103.7 1.6 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F DUF4199 PF13858.6 AMK78401.1 - 0.019 15.4 2.0 0.019 15.4 2.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) UPF0370 PF13980.6 AMK78401.1 - 0.035 14.1 0.1 0.035 14.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Autotransporter PF03797.19 AMK78402.1 - 6.4e-36 124.3 19.7 6.4e-36 124.3 19.7 6.8 2 1 5 7 7 7 1 Autotransporter beta-domain PATR PF12951.7 AMK78402.1 - 8.9e-17 60.9 102.6 7.3e-08 32.4 11.5 16.6 16 2 2 18 18 18 7 Passenger-associated-transport-repeat DUF390 PF04094.14 AMK78402.1 - 0.095 11.0 6.6 0.14 10.4 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) META PF03724.16 AMK78402.1 - 4.7 7.2 25.6 15 5.6 0.2 6.6 6 1 0 6 6 6 0 META domain G8 PF10162.9 AMK78402.1 - 10 6.3 36.3 0.16 12.0 0.2 7.8 4 2 4 9 9 9 0 G8 domain T2SSE PF00437.20 AMK78403.1 - 7.1e-87 290.9 2.7 1e-86 290.4 2.7 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AMK78403.1 - 1.3e-11 44.7 0.2 3.5e-11 43.3 0.1 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_29 PF13555.6 AMK78403.1 - 0.00017 21.3 0.0 0.00046 19.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AMK78403.1 - 0.00021 21.1 0.0 0.00071 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AMK78403.1 - 0.00024 21.6 0.6 0.0047 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 AMK78403.1 - 0.00031 21.0 0.0 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK78403.1 - 0.00066 20.1 0.0 0.0026 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 AMK78403.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 AMK78403.1 - 0.0026 18.3 0.1 0.024 15.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 AMK78403.1 - 0.0084 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 AMK78403.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 AMK78403.1 - 0.041 13.8 0.9 0.5 10.3 0.2 2.3 1 1 0 2 2 2 0 NTPase DUF815 PF05673.13 AMK78403.1 - 0.095 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 AMK78403.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AMK78403.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Herpes_Helicase PF02689.14 AMK78403.1 - 0.19 9.6 0.0 0.25 9.2 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF1722 PF08349.11 AMK78405.1 - 1.8e-37 128.2 0.0 2.6e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) DUF523 PF04463.12 AMK78405.1 - 3.4e-34 117.8 0.0 5.1e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF523) Lipocalin_2 PF08212.12 AMK78406.1 - 5.7e-41 139.8 0.0 6.8e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 AMK78406.1 - 3.1e-07 30.7 0.0 4.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family FAD_binding_7 PF03441.14 AMK78407.1 - 1.6e-75 253.0 5.2 2.2e-75 252.6 5.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 AMK78407.1 - 1.6e-39 135.5 0.0 2.9e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF1731 PF08338.11 AMK78409.1 - 3.7e-21 74.7 0.4 7.1e-21 73.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 AMK78409.1 - 1.1e-17 64.3 0.0 1.4e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 AMK78409.1 - 1.3e-07 31.3 0.0 5.8e-05 22.6 0.1 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 AMK78409.1 - 0.00017 20.8 0.0 0.00036 19.7 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 AMK78409.1 - 0.00026 21.0 0.1 0.00037 20.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_2 PF03446.15 AMK78409.1 - 0.00052 20.2 0.0 0.00098 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 AMK78409.1 - 0.00054 19.5 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 AMK78409.1 - 0.0023 17.1 0.0 0.069 12.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 AMK78409.1 - 0.0063 16.1 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 AMK78409.1 - 0.0068 17.0 0.1 0.014 15.9 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 AMK78409.1 - 0.011 14.9 0.0 0.031 13.4 0.1 1.6 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 AMK78409.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_8 PF13450.6 AMK78409.1 - 0.08 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 AMK78409.1 - 0.083 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 AMK78409.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ferric_reduct PF01794.19 AMK78410.1 - 5.9e-13 49.0 7.6 5.9e-13 49.0 7.6 1.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF4079 PF13301.6 AMK78410.1 - 0.18 11.9 5.3 0.059 13.5 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Oxidored_molyb PF00174.19 AMK78411.1 - 1.5e-28 99.6 0.0 2.2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FA_hydroxylase PF04116.13 AMK78412.1 - 5.1e-24 85.1 14.3 5.1e-24 85.1 14.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PAS_9 PF13426.7 AMK78413.1 - 2.3e-22 79.2 0.0 2.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK78413.1 - 7.7e-11 42.0 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK78413.1 - 1.6e-09 38.0 0.0 1.9e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AMK78413.1 - 1.8e-09 37.7 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK78413.1 - 2.6e-05 24.1 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_12 PF18095.1 AMK78413.1 - 0.00034 20.3 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain Polyketide_cyc2 PF10604.9 AMK78414.1 - 6e-07 29.8 0.0 7.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Herpes_UL43 PF05072.13 AMK78415.1 - 0.1 11.7 0.9 0.12 11.4 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Peptidase_M41 PF01434.18 AMK78416.1 - 1.9e-66 223.5 0.1 3.1e-66 222.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AMK78416.1 - 8.7e-46 155.6 0.0 3.2e-45 153.8 0.0 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AMK78416.1 - 2.5e-12 46.4 0.0 1.4e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 AMK78416.1 - 3.2e-08 33.9 0.1 1.5e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular TIP49 PF06068.13 AMK78416.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 AMK78416.1 - 1.4e-05 25.1 0.2 0.00054 20.0 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK78416.1 - 0.00016 22.1 0.9 0.0077 16.6 0.9 3.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 AMK78416.1 - 0.00017 21.4 0.0 0.0015 18.3 0.0 2.5 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 AMK78416.1 - 0.0014 18.4 0.1 0.0089 15.8 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 AMK78416.1 - 0.0025 18.0 0.0 0.0051 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK78416.1 - 0.0033 17.7 0.1 0.32 11.3 0.1 2.8 2 1 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 AMK78416.1 - 0.0072 15.7 0.5 0.014 14.8 0.5 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 AMK78416.1 - 0.017 15.5 0.0 0.053 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AMK78416.1 - 0.024 14.7 0.0 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 AMK78416.1 - 0.034 14.4 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AdoHcyase_NAD PF00670.21 AMK78416.1 - 0.047 13.8 0.3 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PhoH PF02562.16 AMK78416.1 - 0.059 12.8 0.9 0.31 10.4 0.4 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 AMK78416.1 - 0.094 12.4 0.0 1.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 AMK78416.1 - 0.13 11.5 0.1 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 AMK78416.1 - 0.27 10.7 1.5 0.74 9.3 0.2 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Band_7 PF01145.25 AMK78417.1 - 3.9e-30 105.2 1.1 5.4e-30 104.7 1.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AMK78417.1 - 0.0041 16.8 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 SPFH domain-Band 7 family DivIVA PF05103.13 AMK78417.1 - 1.1 9.3 7.1 0.4 10.8 4.0 1.8 2 0 0 2 2 2 0 DivIVA protein Band_7 PF01145.25 AMK78418.1 - 1.6e-29 103.2 5.2 1.6e-29 103.2 5.2 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family SCAB_CC PF16712.5 AMK78418.1 - 1.1 9.0 5.9 2.7 7.8 5.4 2.0 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Sigma70_r2 PF04542.14 AMK78419.1 - 1.9e-17 62.8 0.0 3.9e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK78419.1 - 4.4e-16 58.1 0.6 1.1e-15 56.8 0.6 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 AMK78419.1 - 0.00039 20.0 1.4 0.0047 16.6 0.3 3.2 2 1 0 2 2 2 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 AMK78419.1 - 0.00066 19.7 5.3 0.0048 17.0 0.0 3.4 4 0 0 4 4 4 1 Sigma-70 region 3 Suppressor_P21 PF11479.8 AMK78419.1 - 0.071 13.3 0.1 8.4 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain MerR_1 PF13411.6 AMK78420.1 - 1.1e-14 54.2 0.1 2.5e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 MerR HTH family regulatory protein B12-binding_2 PF02607.17 AMK78420.1 - 2e-12 47.4 0.0 4.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 AMK78420.1 - 7.7e-09 35.6 0.0 1.9e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 B12 binding domain MerR PF00376.23 AMK78420.1 - 2.2e-07 30.5 0.2 4.4e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 MerR family regulatory protein SUIM_assoc PF16619.5 AMK78420.1 - 2.7 8.1 10.6 4.8 7.3 5.4 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 AMK78421.1 - 0.0048 16.7 0.1 0.041 13.7 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpuA_C PF18033.1 AMK78421.1 - 0.03 14.4 0.1 0.5 10.4 0.0 2.3 2 1 0 2 2 2 0 SpuA C-terminal DUF3804 PF12707.7 AMK78423.1 - 0.07 12.9 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) Polyketide_cyc2 PF10604.9 AMK78425.1 - 9.7e-16 58.3 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AMK78425.1 - 0.052 13.8 0.3 0.075 13.2 0.3 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ODV-E18 PF10717.9 AMK78425.1 - 0.06 13.2 0.9 0.13 12.1 0.9 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 VF530 PF09905.9 AMK78427.1 - 2.4e-34 117.3 0.0 2.7e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 DNA-binding protein VF530 RRM_1 PF00076.22 AMK78428.1 - 1.5e-21 76.0 0.0 1.7e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 AMK78428.1 - 0.0015 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 AMK78428.1 - 0.0027 17.5 0.0 0.0068 16.2 0.0 1.6 1 1 0 1 1 1 1 Occluded RNA-recognition motif DUF2750 PF11042.8 AMK78430.1 - 6.2e-20 71.2 0.1 7.3e-20 70.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2750) Cu-oxidase_3 PF07732.15 AMK78431.1 - 4.9e-46 155.6 0.9 1.3e-37 128.5 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 AMK78431.1 - 4.4e-34 117.9 0.1 1.1e-27 97.1 0.0 4.2 4 2 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 AMK78431.1 - 1.6e-31 108.9 3.7 2.2e-25 89.0 0.4 3.7 4 0 0 4 4 4 3 Multicopper oxidase Cupredoxin_1 PF13473.6 AMK78431.1 - 1.2e-06 28.6 0.0 0.012 15.7 0.0 3.4 3 2 0 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 AMK78431.1 - 0.012 16.0 1.5 0.044 14.2 0.1 2.4 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family CopB PF05275.11 AMK78432.1 - 3.5e-70 235.8 1.7 4.3e-70 235.5 1.7 1.1 1 0 0 1 1 1 1 Copper resistance protein B precursor (CopB) KdgM PF06178.13 AMK78432.1 - 0.017 14.7 0.2 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 Oligogalacturonate-specific porin protein (KdgM) Radical_SAM PF04055.21 AMK78434.1 - 3.1e-10 40.7 0.0 6.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AMK78434.1 - 0.00062 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AMK78434.1 - 0.017 15.4 0.2 0.047 14.0 0.2 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4929 PF16283.5 AMK78434.1 - 0.064 12.2 1.1 0.091 11.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4929) DSPc PF00782.20 AMK78435.1 - 2.9e-08 33.6 0.0 3.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 AMK78435.1 - 2.1e-07 30.8 0.0 2.6e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 AMK78435.1 - 4.5e-05 23.5 0.0 6.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 AMK78435.1 - 0.00038 20.1 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 2OG-FeII_Oxy_4 PF13661.6 AMK78438.1 - 3.4e-07 30.8 0.0 5.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 AMK78438.1 - 8.6e-07 29.8 0.1 1.5e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transglut_core PF01841.19 AMK78440.1 - 1.2e-11 45.0 0.0 2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 AMK78440.1 - 0.032 13.7 0.1 0.44 10.1 0.1 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain Mic1 PF07035.12 AMK78440.1 - 0.08 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like DPCD PF14913.6 AMK78440.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 DPCD protein family Lsm_C PF14894.6 AMK78441.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Lsm C-terminal APT PF03440.14 AMK78444.1 - 0.02 14.9 0.2 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain Proteasome_A_N PF10584.9 AMK78444.1 - 0.53 10.0 5.4 17 5.2 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature OmpA PF00691.20 AMK78447.1 - 0.0079 16.5 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 OmpA family HA PF03457.14 AMK78447.1 - 0.14 12.5 0.8 1.3 9.4 0.2 2.8 1 1 1 2 2 2 0 Helicase associated domain Beta-lactamase2 PF13354.6 AMK78448.1 - 1.9e-06 27.6 0.0 0.00068 19.3 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family Response_reg PF00072.24 AMK78449.1 - 0.0037 17.4 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activat PF00158.26 AMK78450.1 - 3e-67 225.5 0.4 5.1e-67 224.8 0.4 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK78450.1 - 5.7e-17 62.1 0.0 1.6e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 AMK78450.1 - 2e-06 28.2 0.0 3.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_8 PF02954.19 AMK78450.1 - 3.5e-06 26.7 0.1 1.5e-05 24.6 0.1 2.2 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 AMK78450.1 - 7.6e-06 26.0 0.1 1.8e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PAS_8 PF13188.7 AMK78450.1 - 3.1e-05 23.9 0.1 0.00013 21.9 0.1 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK78450.1 - 3.8e-05 23.6 0.0 9.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold MCM PF00493.23 AMK78450.1 - 0.00016 20.9 0.1 0.00027 20.1 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain TIP49 PF06068.13 AMK78450.1 - 0.00036 19.9 0.0 0.00053 19.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 AMK78450.1 - 0.012 15.3 0.1 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 AMK78450.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 AMK78450.1 - 0.05 14.0 0.1 0.092 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AMK78450.1 - 0.069 12.9 0.6 0.21 11.3 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AMK78450.1 - 0.096 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PAS_9 PF13426.7 AMK78450.1 - 0.16 12.2 0.0 0.64 10.3 0.0 2.1 1 0 0 1 1 1 0 PAS domain TonB_dep_Rec PF00593.24 AMK78451.1 - 1.6e-45 156.8 44.3 1.6e-45 156.8 44.3 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK78451.1 - 2.4e-21 76.3 0.4 7.3e-21 74.8 0.4 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain MFS_1 PF07690.16 AMK78452.1 - 3.3e-38 131.5 79.2 2.1e-32 112.4 51.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PilA4 PF18682.1 AMK78453.1 - 0.12 12.7 0.1 0.17 12.3 0.1 1.2 1 0 0 1 1 1 0 Pilin A4 Beta_helix PF13229.6 AMK78454.1 - 4.6e-08 33.1 10.4 4.6e-08 33.1 10.4 1.9 1 1 1 2 2 2 2 Right handed beta helix region Pectate_lyase_3 PF12708.7 AMK78454.1 - 0.0093 15.8 2.3 0.25 11.2 0.4 2.4 1 1 1 2 2 2 2 Pectate lyase superfamily protein GIY-YIG PF01541.24 AMK78455.1 - 0.0045 17.2 0.1 0.0066 16.7 0.1 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF3626 PF12294.8 AMK78455.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) MCPsignal PF00015.21 AMK78456.1 - 1.6e-35 122.5 25.7 1.6e-35 122.5 25.7 3.8 3 1 2 5 5 5 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PilZ PF07238.14 AMK78456.1 - 1.5e-10 41.3 0.0 3.7e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 PilZ domain NPBW PF15180.6 AMK78456.1 - 0.057 13.3 0.7 0.95 9.3 0.4 2.7 2 0 0 2 2 2 0 Neuropeptides B and W TipAS PF07739.13 AMK78456.1 - 1.4 9.5 11.8 4.1 8.0 1.0 4.6 4 1 0 4 4 4 0 TipAS antibiotic-recognition domain GIT_CC PF16559.5 AMK78456.1 - 4.5 7.2 7.5 21 5.1 0.7 3.2 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Prefoldin_3 PF13758.6 AMK78456.1 - 4.7 7.3 11.6 0.42 10.7 1.8 2.8 2 0 0 2 2 2 0 Prefoldin subunit DUF4449 PF14613.6 AMK78456.1 - 7.4 6.7 11.5 1.2 9.3 4.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) T7SS_ESX_EspC PF10824.8 AMK78456.1 - 7.9 7.0 26.2 0.18 12.3 0.4 6.0 4 2 4 8 8 8 0 Excreted virulence factor EspC, type VII ESX diderm CBS PF00571.28 AMK78457.1 - 5.8e-28 97.1 1.3 1.4e-13 51.1 0.8 2.1 2 0 0 2 2 2 2 CBS domain Tyr_Deacylase PF02580.16 AMK78460.1 - 1.4e-45 155.3 0.0 1.7e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GGACT PF06094.12 AMK78461.1 - 2.1e-22 80.0 0.0 2.4e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 AMK78461.1 - 0.0056 17.0 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family Phage_integrase PF00589.22 AMK78462.1 - 2.1e-09 37.4 0.0 6.7e-06 26.0 0.1 2.3 2 0 0 2 2 2 2 Phage integrase family Phage_Integr_2 PF13009.6 AMK78463.1 - 4.3e-94 315.3 0.9 8.4e-94 314.3 0.9 1.5 1 0 0 1 1 1 1 Putative phage integrase PHINT_rpt PF14882.6 AMK78463.1 - 2.1e-12 47.1 7.3 1.6e-05 25.0 0.2 2.5 2 0 0 2 2 2 2 Phage-integrase repeat unit Phage_integrase PF00589.22 AMK78463.1 - 8.3e-06 25.7 0.1 2e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Phage integrase family Rho_N PF07498.12 AMK78463.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain CDI PF02234.19 AMK78464.1 - 0.13 12.4 0.5 0.32 11.2 0.5 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor GreA_GreB_N PF03449.15 AMK78465.1 - 4.6e-26 90.8 2.1 4.6e-26 90.8 2.1 1.4 2 0 0 2 2 2 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 AMK78465.1 - 5.8e-18 64.6 0.0 9e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF1481 PF07356.12 AMK78465.1 - 0.072 12.9 0.9 0.12 12.2 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1481) HR1 PF02185.16 AMK78465.1 - 0.22 11.7 1.7 1 9.5 1.7 1.9 1 1 0 1 1 1 0 Hr1 repeat DEAD PF00270.29 AMK78466.1 - 4.1e-25 88.5 0.0 5.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AMK78466.1 - 9.5e-07 29.0 0.1 1.1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CheR PF01739.18 AMK78466.1 - 0.022 14.2 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain rve PF00665.26 AMK78467.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK78467.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK78467.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK78467.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK78467.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK78467.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK78467.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 HTH_Tnp_1 PF01527.20 AMK78468.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK78468.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK78468.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78468.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK78468.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK78468.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SNF2_N PF00176.23 AMK78469.1 - 1.7e-18 66.5 0.0 5.5e-18 64.8 0.0 1.8 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 AMK78469.1 - 1.7e-17 63.8 0.0 3.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 AMK78469.1 - 3e-07 30.6 0.0 1.4e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AMK78469.1 - 2.3e-06 27.5 0.0 2.9e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HTH_Tnp_1 PF01527.20 AMK78470.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK78470.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK78470.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78470.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK78470.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK78470.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK78471.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK78471.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK78471.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK78471.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK78471.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK78471.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK78471.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 TIR_2 PF13676.6 AMK78473.1 - 7.9e-14 52.3 0.0 1e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 AMK78473.1 - 0.077 12.8 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 TIR domain Ribosomal_S13_N PF08069.12 AMK78473.1 - 0.13 12.4 6.4 14 5.8 3.0 3.4 3 1 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain DUF1488 PF07369.11 AMK78474.1 - 5.4e-11 42.3 0.1 5.9e-11 42.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1488) HupE_UreJ_2 PF13795.6 AMK78475.1 - 0.053 13.2 0.1 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 HupE / UreJ protein GreA_GreB_N PF03449.15 AMK78476.1 - 6.2e-13 48.7 0.7 7.4e-13 48.4 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal FKBP_C PF00254.28 AMK78477.1 - 1.3e-13 51.1 0.0 1.9e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase OEP PF02321.18 AMK78478.1 - 8.4e-32 110.5 30.6 1.6e-17 63.9 10.6 2.9 2 1 0 2 2 2 2 Outer membrane efflux protein HlyD_3 PF13437.6 AMK78479.1 - 4.1e-14 53.2 1.5 5.6e-06 27.0 0.0 3.3 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK78479.1 - 1.2e-11 44.3 8.1 3.1e-11 42.9 0.2 3.3 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AMK78479.1 - 1.2e-10 41.0 9.4 3.2e-05 23.2 6.9 3.7 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 AMK78479.1 - 3.6e-05 23.5 0.0 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme Phage_Mu_Gam PF07352.12 AMK78479.1 - 0.68 9.8 6.0 0.36 10.7 1.2 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein UPF0242 PF06785.11 AMK78479.1 - 2.1 8.4 8.2 11 6.0 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ARGLU PF15346.6 AMK78479.1 - 3.9 7.3 10.9 0.16 11.8 2.9 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 ABC_tran PF00005.27 AMK78480.1 - 3.3e-20 73.0 0.1 5.7e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AMK78480.1 - 5.9e-12 45.8 11.9 8.7e-12 45.3 11.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 AMK78480.1 - 0.026 14.9 1.7 0.065 13.6 0.8 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 AMK78480.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AMK78480.1 - 0.082 13.2 0.1 0.39 11.0 0.0 2.1 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.13 AMK78480.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 AMK78480.1 - 0.21 10.9 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AMK78480.1 - 0.27 11.1 3.6 1.9 8.4 0.4 3.0 3 0 0 3 3 3 0 NACHT domain PEPcase PF00311.17 AMK78482.1 - 2e-267 889.4 0.0 2.4e-267 889.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 AMK78482.1 - 0.002 16.7 0.0 0.0036 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase HTH_1 PF00126.27 AMK78483.1 - 5.7e-18 64.6 0.0 1.2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 AMK78483.1 - 1.1e-12 47.7 0.2 1.6e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_5 PF01022.20 AMK78483.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Methyltransf_16 PF10294.9 AMK78484.1 - 7.1e-13 48.7 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 AMK78484.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78484.1 - 6.5e-06 26.8 0.0 1.3e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78484.1 - 0.00068 20.3 0.0 0.0022 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78484.1 - 0.0022 18.6 0.0 0.012 16.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 AMK78484.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 AMK78484.1 - 0.054 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein TPMT PF05724.11 AMK78485.1 - 4.8e-58 196.4 0.0 5.8e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 AMK78485.1 - 0.00013 22.5 0.0 0.00022 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78485.1 - 0.0013 19.4 0.0 0.0037 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Glyco_hydro_3 PF00933.21 AMK78486.1 - 7.6e-70 235.8 0.0 2.6e-69 234.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 AMK78486.1 - 2.5e-47 161.5 0.0 4.9e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 AMK78486.1 - 2.3e-22 78.9 0.1 4.5e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 AMK78486.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 CARDB Catalase_C PF18011.1 AMK78486.1 - 0.074 12.7 0.2 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain found in long catalases MFS_1 PF07690.16 AMK78487.1 - 1.6e-17 63.5 39.0 1.1e-16 60.7 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CheB_methylest PF01339.17 AMK78488.1 - 3.3e-59 199.4 0.5 6.7e-59 198.4 0.1 1.7 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 AMK78488.1 - 1.8e-24 86.0 0.2 6.3e-24 84.3 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain CheD PF03975.13 AMK78489.1 - 8.7e-26 90.2 0.1 1.2e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction DUF5097 PF17020.5 AMK78489.1 - 0.046 14.1 0.3 0.073 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) CheR PF01739.18 AMK78490.1 - 1.4e-54 184.6 0.0 1.8e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 AMK78490.1 - 1.8e-14 53.1 0.3 4.7e-14 51.8 0.3 1.7 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_31 PF13847.6 AMK78490.1 - 6.6e-07 29.2 0.0 5.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78490.1 - 1.7e-06 28.7 0.0 5.4e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78490.1 - 2.2e-06 28.3 0.0 0.00034 21.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78490.1 - 0.00016 22.3 0.0 0.0025 18.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK78490.1 - 0.00016 21.5 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 AMK78490.1 - 0.0061 15.9 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_2 PF00891.18 AMK78490.1 - 0.097 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MCPsignal PF00015.21 AMK78491.1 - 5.6e-26 91.4 9.9 5.6e-26 91.4 9.9 2.5 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PRTP PF01366.18 AMK78491.1 - 0.03 12.4 1.8 0.042 11.9 1.6 1.3 1 1 0 1 1 1 0 Herpesvirus processing and transport protein BCDHK_Adom3 PF10436.9 AMK78491.1 - 0.034 14.0 0.6 0.074 12.9 0.6 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF4559 PF15112.6 AMK78491.1 - 0.081 12.6 6.9 1.4 8.6 2.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) DUF1664 PF07889.12 AMK78491.1 - 0.095 12.7 7.7 0.58 10.2 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Trep_Strep PF09605.10 AMK78491.1 - 0.1 12.6 1.2 0.69 9.9 0.9 2.2 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CENP-B_dimeris PF09026.10 AMK78491.1 - 0.1 13.0 1.4 0.68 10.3 0.0 2.5 3 0 0 3 3 2 0 Centromere protein B dimerisation domain TMF_TATA_bd PF12325.8 AMK78491.1 - 0.1 12.8 4.4 2.7 8.2 0.0 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4618 PF15397.6 AMK78491.1 - 0.13 11.7 5.0 1.1 8.6 1.3 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) T7SS_ESX_EspC PF10824.8 AMK78491.1 - 0.14 12.6 15.6 0.082 13.4 1.0 4.3 1 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm Sec34 PF04136.15 AMK78491.1 - 0.36 10.7 4.6 8.4 6.3 0.3 3.1 3 1 0 3 3 3 0 Sec34-like family DHR10 PF18595.1 AMK78491.1 - 0.87 9.7 10.5 0.55 10.3 0.9 3.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Serine_rich PF08824.10 AMK78491.1 - 0.94 9.5 10.3 0.47 10.4 3.1 3.0 2 2 1 3 3 3 0 Serine rich protein interaction domain DUF2277 PF10041.9 AMK78491.1 - 1 9.7 5.2 6.8 7.1 0.1 3.8 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) Baculo_PEP_C PF04513.12 AMK78491.1 - 1.2 9.1 14.4 0.76 9.8 1.3 3.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 AMK78491.1 - 1.3 9.7 8.9 17 6.0 1.1 3.8 1 1 3 4 4 4 0 Syntaxin 6, N-terminal HisKA_3 PF07730.13 AMK78491.1 - 1.6 9.3 9.9 1.5 9.4 0.2 4.3 3 1 1 4 4 4 0 Histidine kinase DUF16 PF01519.16 AMK78491.1 - 2 8.9 6.1 21 5.7 0.4 3.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF948 PF06103.11 AMK78491.1 - 2.7 8.3 13.3 1.9e+03 -0.8 11.4 4.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 AMK78491.1 - 5.6 7.1 5.5 11 6.2 0.2 3.2 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family Response_reg PF00072.24 AMK78492.1 - 3e-25 88.6 0.1 3.3e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PT-TG PF14449.6 AMK78492.1 - 0.04 13.8 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Pre-toxin TG STAS_2 PF13466.6 AMK78493.1 - 7.8e-16 58.2 0.1 9.3e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 AMK78493.1 - 7.4e-10 38.5 0.1 9.2e-10 38.2 0.1 1.1 1 0 0 1 1 1 1 STAS domain CheW PF01584.19 AMK78494.1 - 6.5e-27 93.9 0.1 1.2e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 AMK78494.1 - 2.8e-18 66.0 0.2 1.2e-17 64.0 0.2 2.2 1 1 0 1 1 1 1 Hpt domain HATPase_c PF02518.26 AMK78494.1 - 1.1e-16 61.3 0.3 1.1e-15 58.0 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 AMK78494.1 - 2.4e-08 34.2 0.2 2.4e-08 34.2 0.2 3.4 2 1 1 3 3 3 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_3 PF13589.6 AMK78494.1 - 0.0032 17.3 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK78494.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MCPsignal PF00015.21 AMK78495.1 - 5.9e-30 104.3 44.4 1.5e-29 103.0 21.1 4.4 3 1 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 AMK78495.1 - 8.3e-12 45.3 0.2 6.3e-11 42.5 0.1 2.7 2 0 0 2 2 2 1 HAMP domain DUF357 PF04010.13 AMK78495.1 - 0.36 10.9 2.4 1.5 9.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF357) DUF1664 PF07889.12 AMK78495.1 - 0.95 9.5 23.6 0.03 14.4 4.4 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) LOH1CR12 PF10158.9 AMK78495.1 - 1.4 8.9 13.0 2.6 8.1 0.8 3.4 3 0 0 3 3 3 0 Tumour suppressor protein Tweety PF04906.13 AMK78495.1 - 2.7 6.5 17.3 0.03 13.0 3.9 3.3 3 0 0 3 3 3 0 Tweety DUF1054 PF06335.12 AMK78495.1 - 8.2 6.3 8.0 1.5 8.7 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) CheW PF01584.19 AMK78496.1 - 2.9e-33 114.4 1.2 3.5e-33 114.2 1.2 1.1 1 0 0 1 1 1 1 CheW-like domain Hemerythrin PF01814.23 AMK78497.1 - 2.4e-08 34.6 4.5 3.2e-08 34.3 4.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.23 AMK78498.1 - 8.1e-07 29.7 6.3 1e-06 29.4 6.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Syntaxin_2 PF14523.6 AMK78498.1 - 0.01 16.2 0.6 0.017 15.5 0.6 1.4 1 0 0 1 1 1 0 Syntaxin-like protein Homez PF11569.8 AMK78498.1 - 0.11 12.0 1.7 0.6 9.6 0.0 2.6 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez NIT PF08376.10 AMK78499.1 - 2.8e-47 162.1 3.7 2.8e-47 162.1 3.7 2.9 2 1 0 2 2 2 1 Nitrate and nitrite sensing MCPsignal PF00015.21 AMK78499.1 - 5.4e-32 111.0 32.8 2.1e-29 102.5 20.4 4.5 3 1 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain MbeB_N PF04837.12 AMK78499.1 - 0.084 13.2 2.5 0.44 10.9 2.1 2.5 1 1 0 1 1 1 0 MbeB-like, N-term conserved region HSL_N PF06350.12 AMK78499.1 - 0.18 10.7 1.9 1.6 7.6 0.4 2.3 2 0 0 2 2 2 0 Hormone-sensitive lipase (HSL) N-terminus DUF1664 PF07889.12 AMK78499.1 - 2.2 8.3 14.2 2.3 8.3 1.7 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) CdvA PF18822.1 AMK78499.1 - 5.3 6.9 12.2 4 7.3 2.8 3.5 3 1 0 3 3 3 0 CdvA-like coiled-coil domain RmuC PF02646.16 AMK78499.1 - 7.1 5.7 14.6 0.33 10.1 0.2 3.8 2 1 3 5 5 5 0 RmuC family Caskin-tail PF16632.5 AMK78499.1 - 7.4 7.1 9.9 22 5.5 0.1 3.7 3 0 0 3 3 3 0 C-terminal region of Caskin FTHFS PF01268.19 AMK78500.1 - 2.4e-261 867.8 0.5 2.7e-261 867.6 0.5 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 AMK78500.1 - 0.016 15.2 0.4 0.047 13.7 0.3 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AMK78500.1 - 0.075 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain Rib_5-P_isom_A PF06026.14 AMK78501.1 - 4.1e-59 199.0 0.3 2.9e-58 196.3 0.1 1.9 1 1 1 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 AMK78501.1 - 0.00079 19.4 0.2 0.0048 16.9 0.0 2.1 1 1 1 2 2 2 1 DeoR C terminal sensor domain PALP PF00291.25 AMK78502.1 - 2.2e-84 283.4 2.7 2.7e-84 283.0 2.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 AMK78502.1 - 6.9e-45 150.7 0.0 7.9e-23 80.0 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Fructosamin_kin PF03881.14 AMK78503.1 - 6.7e-109 363.5 0.7 8.2e-109 363.3 0.7 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 AMK78503.1 - 1.5e-14 54.5 0.5 1.9e-14 54.2 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1c PF00749.21 AMK78504.1 - 2.1e-112 375.1 0.0 2.6e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 AMK78504.1 - 3.6e-63 212.5 0.0 6e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sigma70_r2 PF04542.14 AMK78505.1 - 3e-16 58.9 0.1 1e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK78505.1 - 2e-15 56.0 0.6 2e-15 56.0 0.6 2.1 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_23 PF13384.6 AMK78505.1 - 0.023 14.5 0.0 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Homeodomain-like domain GerE PF00196.19 AMK78505.1 - 0.024 14.2 0.1 0.9 9.1 0.1 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family IF2_N PF04760.15 AMK78505.1 - 0.026 14.4 0.6 7.6 6.4 0.1 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HTH_25 PF13413.6 AMK78505.1 - 0.1 12.5 1.5 0.15 11.9 0.3 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 AMK78505.1 - 0.11 12.5 0.1 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix Phage_AlpA PF05930.12 AMK78508.1 - 1.1e-05 25.1 0.0 1.2e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) TcpA PF05946.12 AMK78509.1 - 0.062 13.4 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Toprim_3 PF13362.6 AMK78510.1 - 7.1e-07 29.5 0.1 2.8e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AMK78510.1 - 0.00017 22.0 2.2 0.00023 21.5 0.3 2.1 2 0 0 2 2 2 1 Toprim domain CW_binding_1 PF01473.20 AMK78511.1 - 0.0024 18.1 0.1 0.0053 17.0 0.1 1.6 1 0 0 1 1 1 1 Putative cell wall binding repeat Response_reg PF00072.24 AMK78512.1 - 5.3e-20 71.7 0.0 6.4e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain ARL6IP6 PF15062.6 AMK78512.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix CSD PF00313.22 AMK78513.1 - 4.7e-27 93.6 0.8 5.1e-27 93.5 0.8 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 AMK78513.1 - 0.005 16.5 2.3 0.0064 16.2 2.3 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain ABC_membrane PF00664.23 AMK78514.1 - 1.2e-45 156.4 11.1 1.5e-45 156.0 11.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AMK78514.1 - 6.2e-34 117.5 0.0 1.3e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AMK78514.1 - 4.4e-07 29.6 0.0 3.7e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AMK78514.1 - 0.00083 19.3 0.3 0.004 17.0 0.1 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AMK78514.1 - 0.0015 19.0 0.1 0.058 13.8 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK78514.1 - 0.0016 18.9 0.4 0.0044 17.4 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 AMK78514.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 AMK78514.1 - 0.004 16.0 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 AMK78514.1 - 0.0047 17.2 0.1 0.028 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AMK78514.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AMK78514.1 - 0.023 14.4 0.0 0.079 12.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 AMK78514.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK78514.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 AMK78514.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AMK78514.1 - 0.088 12.1 0.1 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 AMK78514.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Virul_fac_BrkB PF03631.15 AMK78515.1 - 7.8e-47 160.1 25.4 1.1e-46 159.5 25.4 1.2 1 0 0 1 1 1 1 Virulence factor BrkB DUF742 PF05331.11 AMK78515.1 - 0.022 14.6 0.3 0.04 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) DUF2839 PF10999.8 AMK78515.1 - 0.75 10.2 5.9 0.3 11.5 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Response_reg PF00072.24 AMK78516.1 - 1.8e-27 95.7 0.3 2.1e-27 95.5 0.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain EAL PF00563.20 AMK78517.1 - 4.6e-57 193.3 0.0 7.8e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 EAL domain Response_reg PF00072.24 AMK78517.1 - 3.7e-24 85.0 0.1 1.5e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain GGDEF PF00990.21 AMK78517.1 - 3.1e-20 72.6 0.1 5.6e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK78517.1 - 2.2e-14 53.6 0.1 7.5e-14 51.9 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK78517.1 - 2.3e-12 46.9 0.0 5.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AMK78517.1 - 1.8e-11 44.1 0.1 2.8e-10 40.4 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AMK78517.1 - 3.3e-09 37.0 0.0 8.3e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK78517.1 - 0.0011 18.9 0.0 0.0039 17.2 0.0 2.0 1 0 0 1 1 1 1 PAS domain Thx PF17070.5 AMK78517.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 30S ribosomal protein Thx HHH_5 PF14520.6 AMK78517.1 - 0.14 12.8 0.0 0.96 10.1 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix domain CarboxypepD_reg PF13620.6 AMK78518.1 - 2.6e-13 50.1 0.3 2.6e-13 50.1 0.3 2.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain TonB_dep_Rec PF00593.24 AMK78518.1 - 2.9e-08 34.0 44.5 2.9e-08 34.0 44.5 3.2 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK78518.1 - 0.00013 22.5 1.9 0.00055 20.5 1.9 2.1 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain CarbopepD_reg_2 PF13715.6 AMK78518.1 - 0.0021 18.0 0.1 0.0068 16.4 0.0 2.0 2 0 0 2 2 2 1 CarboxypepD_reg-like domain DUF2012 PF09430.10 AMK78518.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF4154 PF13689.6 AMK78519.1 - 5.4e-34 117.5 0.0 6.4e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like Response_reg PF00072.24 AMK78520.1 - 1.9e-51 173.0 1.3 1.7e-26 92.6 0.4 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AMK78520.1 - 4.6e-30 104.4 0.0 8.8e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 AMK78520.1 - 5.1e-29 100.8 0.0 1.4e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AMK78520.1 - 1.6e-20 72.9 0.2 1.6e-20 72.9 0.2 3.7 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain CHASE8 PF17152.4 AMK78520.1 - 3.7e-15 56.0 0.0 2e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 Periplasmic sensor domain HAMP PF00672.25 AMK78520.1 - 2e-06 28.1 0.0 8.8e-06 26.0 0.0 2.2 1 0 0 1 1 1 1 HAMP domain Hpt PF01627.23 AMK78520.1 - 3.6e-06 27.2 0.2 3.6e-06 27.2 0.2 3.6 3 1 1 4 4 4 1 Hpt domain HATPase_c_3 PF13589.6 AMK78520.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0242 PF06785.11 AMK78520.1 - 2.2 8.3 5.8 0.22 11.6 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CCP_MauG PF03150.14 AMK78521.1 - 3.7e-59 199.7 0.0 4.2e-55 186.5 0.0 2.1 2 0 0 2 2 2 2 Di-haem cytochrome c peroxidase Cytochrom_C PF00034.21 AMK78521.1 - 6.2e-11 43.3 0.0 1.6e-05 26.0 0.0 2.6 2 0 0 2 2 2 2 Cytochrome c DUF1924 PF09086.11 AMK78521.1 - 0.00095 19.5 0.2 0.39 11.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1924) Cytochrome_C7 PF14522.6 AMK78521.1 - 0.0014 18.6 0.1 2.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 AMK78521.1 - 0.0063 16.2 0.2 4.7 7.0 0.0 2.4 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) PSCyt3 PF07627.11 AMK78521.1 - 0.017 15.3 0.0 7.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Cytochrom_c3_2 PF14537.6 AMK78521.1 - 0.085 13.3 0.1 20 5.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c3 Cytochrome_CBB3 PF13442.6 AMK78521.1 - 0.24 11.8 8.3 6 7.3 0.4 3.5 2 2 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III GSu_C4xC__C2xCH PF09698.10 AMK78521.1 - 5.7 7.8 6.9 33 5.4 0.4 3.3 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) AlaDh_PNT_C PF01262.21 AMK78522.1 - 2.2e-81 272.2 3.3 2.2e-81 272.2 3.3 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AMK78522.1 - 4.5e-45 153.3 0.0 1e-44 152.2 0.0 1.6 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 AMK78522.1 - 1.1e-06 28.1 0.2 2.2e-06 27.1 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 AMK78522.1 - 4.1e-05 22.9 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AMK78522.1 - 5.7e-05 23.6 0.1 0.00012 22.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 AMK78522.1 - 0.00012 22.1 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AMK78522.1 - 0.0018 18.2 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AMK78522.1 - 0.0078 16.6 0.2 0.015 15.7 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.22 AMK78522.1 - 0.029 13.4 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 AMK78522.1 - 0.041 14.1 0.4 0.076 13.3 0.4 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 AMK78522.1 - 0.049 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 AMK78522.1 - 0.055 14.0 0.1 0.091 13.3 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Sacchrp_dh_NADP PF03435.18 AMK78522.1 - 0.21 11.8 1.0 0.7 10.1 0.6 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 AMK78522.1 - 1.2 8.4 3.5 1.9 7.8 3.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF87 PF01935.17 AMK78523.1 - 1.5e-35 123.4 0.0 5.4e-35 121.5 0.0 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AMK78523.1 - 2.9e-05 23.5 0.0 0.05 12.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF853 PF05872.12 AMK78523.1 - 3.7e-05 22.5 0.0 0.00051 18.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.9 AMK78523.1 - 0.0021 17.0 0.0 0.0057 15.6 0.0 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 AMK78523.1 - 0.01 16.1 0.0 0.071 13.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 AMK78523.1 - 0.014 15.9 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.7 AMK78523.1 - 0.13 11.2 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 AMK78523.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF4347 PF14252.6 AMK78524.1 - 1.1e-49 168.5 3.3 1.1e-49 168.5 3.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4347) SWM_repeat PF13753.6 AMK78524.1 - 3e-13 49.7 2.2 3e-13 49.7 2.2 8.6 9 1 0 9 9 9 1 Putative flagellar system-associated repeat Big_6 PF17936.1 AMK78524.1 - 2.9e-08 33.9 20.6 1.4e-06 28.5 7.7 21.0 21 2 0 21 21 21 6 Bacterial Ig domain Big_3_3 PF13750.6 AMK78524.1 - 3.5e-07 30.0 10.3 1.4e-06 28.1 3.6 16.4 16 3 2 18 18 18 3 Bacterial Ig-like domain (group 3) DUF4625 PF15418.6 AMK78524.1 - 0.0038 17.5 1.1 40 4.4 0.0 6.4 7 0 0 7 7 7 0 Domain of unknown function (DUF4625) Big_7 PF17957.1 AMK78524.1 - 0.007 17.1 6.4 0.007 17.1 6.4 23.6 23 3 3 26 26 26 4 Bacterial Ig domain Big_3_4 PF13754.6 AMK78524.1 - 0.077 12.7 3.7 1.8 8.4 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function He_PIG PF05345.12 AMK78524.1 - 0.12 12.6 0.0 0.12 12.6 0.0 17.3 18 2 0 18 18 18 0 Putative Ig domain FG-GAP PF01839.23 AMK78524.1 - 0.7 10.1 11.8 0.53 10.5 0.4 5.0 3 0 0 3 3 3 0 FG-GAP repeat Sulfotransfer_3 PF13469.6 AMK78525.1 - 1e-16 62.0 0.0 1.8e-15 58.0 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 AMK78525.1 - 9.8e-09 35.1 0.0 4e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 AMK78525.1 - 0.064 13.1 0.1 0.12 12.1 0.1 1.6 1 1 0 1 1 1 0 Sulfotransferase domain Sulphotransf PF09037.10 AMK78525.1 - 0.091 12.3 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase PATR PF12951.7 AMK78526.1 - 9.6e-45 150.4 154.4 2.4e-10 40.4 5.4 36.7 35 5 4 39 39 39 11 Passenger-associated-transport-repeat DUF4347 PF14252.6 AMK78526.1 - 2.7e-36 124.9 1.5 2.7e-36 124.9 1.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4347) Cadherin_3 PF16184.5 AMK78526.1 - 0.00013 21.9 1.0 3.5 7.7 0.0 4.8 5 0 0 5 5 5 2 Cadherin-like PDZ_1 PF12812.7 AMK78526.1 - 1.7 8.7 6.2 36 4.5 0.1 4.9 4 1 0 4 4 4 0 PDZ-like domain OEP PF02321.18 AMK78527.1 - 5.2e-27 94.9 27.0 8.6e-17 61.6 11.1 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_3 PF13437.6 AMK78528.1 - 6e-15 55.9 0.1 2.5e-12 47.4 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK78528.1 - 4.1e-13 49.1 0.1 7.2e-13 48.3 0.1 1.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AMK78528.1 - 2.7e-12 46.3 0.4 1.2e-05 25.0 0.3 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK78528.1 - 0.0002 21.1 0.0 0.087 12.7 0.0 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme OST_P2 PF18235.1 AMK78528.1 - 0.073 13.0 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain PTS_EIIA_1 PF00358.20 AMK78528.1 - 0.097 12.4 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 AMK78528.1 - 0.1 12.6 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 AMK78529.1 - 7.6e-16 58.7 0.8 4.8e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK78529.1 - 2.7e-07 30.1 0.8 4.9e-07 29.2 0.8 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AMK78529.1 - 0.00037 20.3 0.6 0.0012 18.6 0.6 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like MetOD2 PF18548.1 AMK78529.1 - 0.03 14.4 0.5 0.051 13.7 0.5 1.3 1 0 0 1 1 1 0 Metanogen output domain 2 HlyD_3 PF13437.6 AMK78530.1 - 2.3e-11 44.3 0.1 2e-08 34.9 0.0 2.6 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK78530.1 - 1.1e-08 34.7 1.3 2.4e-06 27.2 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AMK78530.1 - 5.7e-07 29.0 0.7 9.5e-07 28.2 0.7 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Peptidase_M50 PF02163.22 AMK78530.1 - 0.002 17.4 6.6 0.0072 15.6 2.6 2.3 1 1 0 2 2 2 1 Peptidase family M50 Peptidase_M23 PF01551.22 AMK78530.1 - 0.19 12.0 0.0 0.51 10.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M23 Cytochrom_D1 PF02239.16 AMK78532.1 - 1.8e-18 66.2 1.9 4.6e-07 28.7 0.0 3.4 1 1 1 3 3 3 3 Cytochrome D1 heme domain Lactonase PF10282.9 AMK78532.1 - 9.2e-16 58.0 0.1 0.00015 21.2 0.0 4.0 1 1 3 4 4 4 3 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 AMK78532.1 - 5e-12 45.9 1.6 0.1 12.9 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 AMK78532.1 - 2e-11 44.0 0.7 0.0018 17.9 0.1 3.7 2 1 2 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Me-amine-dh_H PF06433.11 AMK78532.1 - 3.2e-08 32.8 0.9 0.01 14.8 0.0 3.7 1 1 2 4 4 4 3 Methylamine dehydrogenase heavy chain (MADH) Arylesterase PF01731.20 AMK78532.1 - 5.6e-08 32.9 0.2 0.86 9.9 0.0 5.0 4 1 1 5 5 5 2 Arylesterase DUF4221 PF13970.6 AMK78532.1 - 1.6e-07 31.2 0.0 0.26 10.8 0.0 4.0 1 1 3 4 4 4 2 Domain of unknown function (DUF4221) Phytase-like PF13449.6 AMK78532.1 - 3.5e-05 23.9 0.6 0.014 15.3 0.1 3.2 1 1 1 2 2 2 2 Esterase-like activity of phytase Glu_cyclase_2 PF05096.12 AMK78532.1 - 8.9e-05 22.0 0.3 0.053 12.9 0.0 3.0 1 1 2 3 3 3 1 Glutamine cyclotransferase PD40 PF07676.12 AMK78532.1 - 0.00013 21.8 0.1 1.1 9.3 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat NHL PF01436.21 AMK78532.1 - 0.00024 21.0 0.8 16 5.8 0.0 6.1 7 1 1 8 8 7 0 NHL repeat WD40 PF00400.32 AMK78532.1 - 0.00028 21.6 0.0 2.1 9.3 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ PF01011.21 AMK78532.1 - 0.00057 19.7 0.6 0.18 11.8 0.0 3.7 4 0 0 4 4 3 1 PQQ enzyme repeat Str_synth PF03088.16 AMK78532.1 - 0.012 15.8 0.0 27 5.0 0.0 4.1 4 1 1 5 5 4 0 Strictosidine synthase PQQ_3 PF13570.6 AMK78532.1 - 0.016 15.7 2.2 0.23 12.0 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain DUF1513 PF07433.11 AMK78532.1 - 0.023 13.8 0.5 9.2 5.3 0.1 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1513) FlgD_ig PF13860.6 AMK78532.1 - 0.28 11.1 4.4 5.2 7.0 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain ABC_tran PF00005.27 AMK78533.1 - 5.5e-34 117.6 0.0 8.6e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK78533.1 - 7.7e-07 29.2 0.2 0.00026 20.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AMK78533.1 - 0.00011 22.7 1.2 0.00018 21.9 1.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AMK78533.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AMK78533.1 - 0.00028 21.2 0.1 0.00051 20.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AMK78533.1 - 0.00052 19.8 0.0 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AMK78533.1 - 0.00059 20.4 0.2 0.0013 19.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AMK78533.1 - 0.00088 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 AMK78533.1 - 0.0029 17.1 0.1 0.013 15.0 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AMK78533.1 - 0.0034 17.0 0.1 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain DLIC PF05783.11 AMK78533.1 - 0.0078 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 AMK78533.1 - 0.048 13.7 0.0 0.075 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 AMK78533.1 - 0.049 12.8 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 AMK78533.1 - 0.057 13.1 0.1 0.38 10.4 0.0 2.1 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 AMK78533.1 - 0.096 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MutS_V PF00488.21 AMK78533.1 - 0.15 12.0 0.2 11 6.0 0.0 2.2 2 0 0 2 2 2 0 MutS domain V AAA_13 PF13166.6 AMK78533.1 - 0.16 10.5 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 AMK78534.1 - 3e-29 101.9 20.3 3e-29 101.9 20.3 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AMK78534.1 - 5.2e-15 55.4 23.7 5.2e-15 55.4 23.7 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AMK78534.1 - 8.6e-13 48.2 13.3 8.6e-13 48.2 13.3 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein PEP-CTERM PF07589.11 AMK78535.1 - 0.021 14.9 0.7 0.043 13.9 0.7 1.6 1 0 0 1 1 1 0 PEP-CTERM motif DUF1097 PF06496.11 AMK78536.1 - 1.1e-29 103.4 26.6 1.3e-29 103.2 26.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1097) TssN PF17555.2 AMK78536.1 - 0.07 12.5 2.9 0.1 12.0 2.9 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN HMGL-like PF00682.19 AMK78537.1 - 1.1e-47 162.8 0.1 1.5e-47 162.4 0.1 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AMK78537.1 - 2.4e-18 66.3 0.1 7.2e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain VapB_antitoxin PF09957.9 AMK78538.1 - 1.1e-06 28.4 1.3 1.5e-06 28.0 1.3 1.2 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB PIN PF01850.21 AMK78539.1 - 6e-06 26.8 0.0 8.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain Phage_Mu_Gp45 PF06890.12 AMK78540.1 - 0.15 11.8 0.6 0.64 9.8 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein Transposase_mut PF00872.18 AMK78543.1 - 4.7e-117 391.1 0.0 6.1e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AMK78543.1 - 0.00018 21.9 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 AMK78543.1 - 0.077 12.7 0.0 9.4 5.9 0.1 2.0 1 1 1 2 2 2 0 Transposase DUF4363 PF14276.6 AMK78543.1 - 0.098 12.8 0.2 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Iso_dh PF00180.20 AMK78545.1 - 2.1e-106 356.0 0.0 2.4e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 AMK78545.1 - 0.04 13.3 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA MarC PF01914.17 AMK78546.1 - 1.1e-58 197.9 11.3 1.3e-58 197.8 11.3 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein LysE PF01810.18 AMK78546.1 - 0.00017 21.1 8.8 0.00056 19.4 8.8 1.7 1 1 0 1 1 1 1 LysE type translocator DUF1980 PF09323.10 AMK78546.1 - 0.004 17.1 0.8 0.032 14.1 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1980) PAT1 PF09770.9 AMK78546.1 - 0.096 10.9 0.3 0.12 10.6 0.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ETRAMP PF09716.10 AMK78546.1 - 0.39 10.8 3.2 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3087 PF11286.8 AMK78546.1 - 2.7 7.4 10.0 4 6.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Trp_oprn_chp PF09534.10 AMK78546.1 - 4.1 7.2 12.0 0.81 9.5 4.8 2.5 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RseC_MucC PF04246.12 AMK78546.1 - 6.1 6.8 12.1 0.53 10.2 1.1 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pox_A14 PF05767.12 AMK78546.1 - 6.2 7.1 8.1 0.65 10.2 0.2 2.8 2 2 2 4 4 4 0 Poxvirus virion envelope protein A14 EthD PF07110.11 AMK78547.1 - 2.7e-07 31.6 0.1 4e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 AMK78547.1 - 0.027 14.9 0.0 0.069 13.6 0.0 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase LysR_substrate PF03466.20 AMK78548.1 - 2.8e-37 128.1 0.3 4e-37 127.6 0.3 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK78548.1 - 4.3e-19 68.2 0.0 7.8e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CheB_methylest PF01339.17 AMK78549.1 - 5.3e-55 185.7 0.0 1e-54 184.8 0.0 1.5 1 0 0 1 1 1 1 CheB methylesterase CheR PF01739.18 AMK78549.1 - 1.1e-51 175.1 0.0 1.8e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain PAS_10 PF13596.6 AMK78549.1 - 7e-33 113.4 0.5 4e-32 111.0 0.5 2.4 2 0 0 2 2 1 1 PAS domain CheR_N PF03705.15 AMK78549.1 - 9.6e-15 54.0 2.7 2.2e-14 52.9 2.7 1.7 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain PAS_4 PF08448.10 AMK78549.1 - 3.7e-07 30.4 0.0 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold FapA PF03961.13 AMK78549.1 - 2.9e-05 22.9 4.2 4.2e-05 22.3 4.2 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Rootletin PF15035.6 AMK78549.1 - 3.3e-05 24.0 5.7 8.8e-05 22.6 5.7 1.7 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion WEMBL PF05701.11 AMK78549.1 - 0.00012 21.0 11.7 0.00017 20.5 11.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Fez1 PF06818.15 AMK78549.1 - 0.00028 21.4 8.3 0.00049 20.6 8.3 1.3 1 0 0 1 1 1 1 Fez1 Golgin_A5 PF09787.9 AMK78549.1 - 0.00032 20.3 13.5 0.00054 19.5 13.5 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 OmpH PF03938.14 AMK78549.1 - 0.00043 20.6 15.0 0.0011 19.3 15.0 1.7 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) AIP3 PF03915.13 AMK78549.1 - 0.00046 19.4 4.6 0.00075 18.7 4.6 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 UPF0242 PF06785.11 AMK78549.1 - 0.00079 19.6 8.8 0.0016 18.6 8.8 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 AMK78549.1 - 0.00092 18.6 9.5 0.0015 17.9 9.5 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase IL12 PF03039.14 AMK78549.1 - 0.0014 18.0 1.2 0.0027 17.1 1.2 1.4 1 0 0 1 1 1 1 Interleukin-12 alpha subunit ATG16 PF08614.11 AMK78549.1 - 0.0019 18.5 17.1 0.0036 17.6 17.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 AMK78549.1 - 0.0019 17.1 15.5 0.0033 16.4 15.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein PAS_9 PF13426.7 AMK78549.1 - 0.0023 18.2 0.2 0.23 11.8 0.1 3.4 3 0 0 3 3 3 1 PAS domain HAUS-augmin3 PF14932.6 AMK78549.1 - 0.0028 17.3 9.3 0.0051 16.4 9.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Tropomyosin PF00261.20 AMK78549.1 - 0.0028 17.0 12.4 0.0054 16.1 12.4 1.4 1 0 0 1 1 1 1 Tropomyosin Lebercilin PF15619.6 AMK78549.1 - 0.0029 17.3 16.6 0.0061 16.2 16.6 1.5 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 AMK78549.1 - 0.0029 17.1 16.4 0.0055 16.2 16.4 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 AMK78549.1 - 0.0046 17.0 20.3 0.0095 16.0 20.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 AMK78549.1 - 0.0046 17.0 19.2 0.0099 15.9 19.2 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 AMK78549.1 - 0.0051 16.4 6.6 0.007 16.0 5.5 1.7 2 0 0 2 2 1 1 Exonuclease VII, large subunit DUF4407 PF14362.6 AMK78549.1 - 0.011 15.1 7.6 0.023 14.0 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IFT57 PF10498.9 AMK78549.1 - 0.014 14.4 13.7 0.023 13.6 13.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF812 PF05667.11 AMK78549.1 - 0.016 14.1 10.7 0.024 13.5 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FH2 PF02181.23 AMK78549.1 - 0.017 14.2 7.3 0.031 13.4 7.3 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF1664 PF07889.12 AMK78549.1 - 0.024 14.7 5.2 0.066 13.2 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 AMK78549.1 - 0.027 13.1 6.1 0.045 12.4 6.1 1.3 1 0 0 1 1 1 0 AAA domain DHHA1 PF02272.19 AMK78549.1 - 0.034 14.5 2.4 3.7 8.0 1.9 3.1 3 0 0 3 3 2 0 DHHA1 domain HIP1_clath_bdg PF16515.5 AMK78549.1 - 0.037 14.6 16.9 0.13 12.9 16.9 2.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 AMK78549.1 - 0.039 14.2 11.2 0.15 12.3 11.2 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 AMK78549.1 - 0.04 13.9 11.3 0.11 12.4 11.3 1.8 1 0 0 1 1 1 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 AMK78549.1 - 0.04 14.1 17.3 0.085 13.1 17.3 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 AMK78549.1 - 0.046 13.0 16.2 0.087 12.1 16.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Peptidase_S64 PF08192.11 AMK78549.1 - 0.05 12.1 5.4 0.07 11.6 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Atg14 PF10186.9 AMK78549.1 - 0.055 12.5 7.0 0.1 11.7 7.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3552 PF12072.8 AMK78549.1 - 0.084 12.3 13.5 0.15 11.5 13.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3584 PF12128.8 AMK78549.1 - 0.086 10.4 15.3 0.12 9.9 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 AMK78549.1 - 0.088 12.1 17.3 0.17 11.3 17.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4795 PF16043.5 AMK78549.1 - 0.11 12.1 8.6 0.21 11.1 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Prefoldin_3 PF13758.6 AMK78549.1 - 0.12 12.5 8.5 1.3 9.2 0.6 2.7 1 1 1 2 2 2 0 Prefoldin subunit Prominin PF05478.11 AMK78549.1 - 0.15 10.0 8.2 0.23 9.4 8.2 1.2 1 0 0 1 1 1 0 Prominin Fzo_mitofusin PF04799.13 AMK78549.1 - 0.16 11.5 7.1 0.36 10.3 7.1 1.6 1 0 0 1 1 1 0 fzo-like conserved region GrpE PF01025.19 AMK78549.1 - 0.17 11.5 10.3 0.46 10.1 10.3 1.7 1 0 0 1 1 1 0 GrpE ZnuA PF01297.17 AMK78549.1 - 0.18 11.2 1.4 0.37 10.1 1.4 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic HOOK PF05622.12 AMK78549.1 - 0.19 9.8 16.0 0.29 9.2 16.0 1.1 1 0 0 1 1 1 0 HOOK protein DUF3138 PF11336.8 AMK78549.1 - 0.2 10.2 1.8 0.29 9.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF745 PF05335.13 AMK78549.1 - 0.22 11.2 12.6 0.41 10.3 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.6 AMK78549.1 - 0.23 11.9 18.7 0.39 11.2 14.1 3.0 2 1 1 3 3 3 0 Snapin/Pallidin Filament PF00038.21 AMK78549.1 - 0.23 11.0 16.0 0.44 10.1 16.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein zf-C4H2 PF10146.9 AMK78549.1 - 0.25 11.6 6.0 0.49 10.7 6.0 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein USP8_interact PF08941.10 AMK78549.1 - 0.3 10.9 3.7 5.8 6.7 4.8 2.2 2 0 0 2 2 2 0 USP8 interacting DUF4527 PF15030.6 AMK78549.1 - 0.31 10.5 11.3 0.72 9.2 11.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4527) APG6_N PF17675.1 AMK78549.1 - 0.33 11.5 19.0 0.91 10.1 19.0 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 AMK78549.1 - 0.35 8.7 4.3 0.47 8.3 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.10 AMK78549.1 - 0.35 11.2 10.9 3.4 8.0 6.3 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 AMK78549.1 - 0.41 10.7 17.9 0.78 9.8 17.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DASH_Duo1 PF08651.10 AMK78549.1 - 0.43 10.4 13.6 3.5 7.5 1.1 2.9 1 1 0 2 2 2 0 DASH complex subunit Duo1 DUF2203 PF09969.9 AMK78549.1 - 0.44 11.3 6.7 1.1 10.0 6.7 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 AMK78549.1 - 0.87 8.4 5.0 1.3 7.8 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein COG5 PF10392.9 AMK78549.1 - 1.3 9.2 10.2 3 8.0 10.2 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TMPIT PF07851.13 AMK78549.1 - 1.4 8.1 10.0 2.2 7.4 10.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein 5_nucleotid PF05761.14 AMK78549.1 - 1.4 7.7 4.9 2.2 7.1 4.9 1.2 1 0 0 1 1 1 0 5' nucleotidase family BST2 PF16716.5 AMK78549.1 - 1.6 9.3 16.8 4.6 7.9 16.8 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Occludin_ELL PF07303.13 AMK78549.1 - 1.7 9.4 7.1 5.5 7.8 7.1 1.8 1 0 0 1 1 1 0 Occludin homology domain FUSC PF04632.12 AMK78549.1 - 1.8 7.0 4.6 2.6 6.5 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG2 PF06148.11 AMK78549.1 - 2.1 8.4 11.2 14 5.8 11.2 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.6 AMK78549.1 - 2.4 8.7 11.3 1.2e+02 3.1 11.3 2.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.9 AMK78549.1 - 2.4 8.5 21.1 54 4.2 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lectin_N PF03954.14 AMK78549.1 - 2.4 7.9 11.2 7.5 6.3 11.2 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain UPF0449 PF15136.6 AMK78549.1 - 3 8.4 16.8 23 5.5 6.9 3.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Phage_GPO PF05929.11 AMK78549.1 - 3.1 7.4 10.6 19 4.7 7.7 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cytochrom_B562 PF07361.11 AMK78549.1 - 3.3 8.4 9.5 6.4 7.5 4.7 2.4 1 1 0 1 1 1 0 Cytochrome b562 Fmp27_WPPW PF10359.9 AMK78549.1 - 3.6 6.3 11.9 5.3 5.8 11.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Rx_N PF18052.1 AMK78549.1 - 3.7 7.9 9.6 3.7 7.9 3.4 2.7 1 1 1 2 2 2 0 Rx N-terminal domain WXG100 PF06013.12 AMK78549.1 - 3.7 7.8 11.0 8.8 6.6 3.8 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF4200 PF13863.6 AMK78549.1 - 5.2 7.5 18.5 1.7e+02 2.6 18.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 AMK78549.1 - 5.3 7.7 14.8 1.3e+02 3.2 14.8 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FemAB PF02388.16 AMK78549.1 - 7.3 5.3 10.2 11 4.7 10.2 1.2 1 0 0 1 1 1 0 FemAB family Fib_alpha PF08702.10 AMK78549.1 - 8.7 6.5 13.4 19 5.4 13.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EAL PF00563.20 AMK78550.1 - 1.3e-72 244.2 0.4 1.3e-71 240.9 0.0 2.4 3 0 0 3 3 3 1 EAL domain GGDEF PF00990.21 AMK78550.1 - 1.6e-55 187.3 0.3 1.6e-55 187.3 0.3 1.7 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK78550.1 - 5.8e-22 77.9 0.0 8.4e-16 58.1 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AMK78550.1 - 2.7e-13 50.2 0.0 5.7e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 AMK78550.1 - 9.6e-12 44.9 0.0 3e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 AMK78550.1 - 1.2e-09 38.3 0.0 8.5e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AMK78550.1 - 7.6e-08 32.2 0.0 7.5e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 AMK78550.1 - 0.04 14.1 0.0 0.47 10.6 0.0 2.5 1 1 0 1 1 1 0 PAS fold RNA_pol_A_CTD PF03118.15 AMK78550.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain BON PF04972.17 AMK78551.1 - 1.1e-14 54.5 2.3 1.1e-14 54.5 2.3 2.3 2 1 0 2 2 2 1 BON domain Apolipoprotein PF01442.18 AMK78551.1 - 2.3e-05 24.4 7.5 3.4e-05 23.8 7.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.6 AMK78551.1 - 0.00058 20.1 11.8 0.00058 20.1 11.8 3.7 1 1 2 3 3 3 1 MT0933-like antitoxin protein DUF4995 PF16386.5 AMK78551.1 - 0.0011 18.9 3.9 0.01 15.8 0.2 2.5 1 1 1 2 2 2 1 Domain of unknown function ApoLp-III PF07464.11 AMK78551.1 - 0.0063 16.6 11.0 0.0063 16.6 11.0 1.5 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 AMK78551.1 - 0.0071 16.9 11.5 0.12 13.0 3.9 2.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 AMK78551.1 - 0.018 15.3 1.4 0.027 14.7 1.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4192 PF13830.6 AMK78551.1 - 0.022 14.8 1.7 0.028 14.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) UPF0239 PF06783.11 AMK78551.1 - 0.043 14.0 2.9 0.044 14.0 0.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0239) DUF948 PF06103.11 AMK78551.1 - 0.064 13.5 2.3 0.93 9.8 0.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 AMK78551.1 - 0.066 12.6 5.5 0.097 12.0 5.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF842 PF05811.13 AMK78551.1 - 0.075 12.7 1.9 0.24 11.1 2.1 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Smg8_Smg9 PF10220.9 AMK78551.1 - 0.085 11.2 2.2 0.1 10.9 2.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF3584 PF12128.8 AMK78551.1 - 0.17 9.4 8.6 0.21 9.0 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BshC PF10079.9 AMK78551.1 - 0.18 10.5 3.7 0.23 10.2 3.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4679 PF15728.5 AMK78551.1 - 0.32 10.0 3.8 0.4 9.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) HisKA_3 PF07730.13 AMK78551.1 - 0.32 11.5 5.1 3.1 8.4 0.9 2.8 1 1 2 3 3 3 0 Histidine kinase CAP18_C PF12153.8 AMK78551.1 - 0.46 10.4 3.3 0.52 10.2 1.1 2.2 1 1 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) Phage_Gp19 PF09355.10 AMK78551.1 - 0.67 10.4 6.8 1 9.8 2.4 2.4 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 TMPIT PF07851.13 AMK78551.1 - 0.8 8.9 3.4 1.1 8.4 3.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 AMK78551.1 - 0.85 10.0 15.0 2.5 8.5 15.0 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YtxH PF12732.7 AMK78551.1 - 0.9 10.1 15.6 0.21 12.1 5.7 2.6 1 1 1 2 2 2 0 YtxH-like protein DUF1664 PF07889.12 AMK78551.1 - 1.1 9.3 5.6 4.5 7.3 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.13 AMK78551.1 - 2.8 8.2 12.0 79 3.5 10.4 2.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal XhlA PF10779.9 AMK78551.1 - 3.5 7.9 6.2 4.6 7.5 0.6 2.5 1 1 2 3 3 3 0 Haemolysin XhlA MbeB_N PF04837.12 AMK78551.1 - 4.2 7.8 10.6 2.7 8.4 0.8 2.8 3 1 0 3 3 2 0 MbeB-like, N-term conserved region DUF1542 PF07564.11 AMK78551.1 - 5.3 7.2 22.8 5.5 7.2 20.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) DUF1207 PF06727.11 AMK78552.1 - 1.4e-163 543.8 0.0 1.6e-163 543.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1207) PLA1 PF02253.15 AMK78552.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase A1 DUF2383 PF09537.10 AMK78553.1 - 8.9e-13 48.6 0.2 1.3e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Ferritin PF00210.24 AMK78553.1 - 0.0054 16.7 0.7 0.0083 16.1 0.7 1.3 1 1 0 1 1 1 1 Ferritin-like domain PEP-utilisers_N PF05524.13 AMK78553.1 - 0.0082 16.3 0.3 2.1 8.6 0.1 2.3 2 0 0 2 2 2 2 PEP-utilising enzyme, N-terminal Ferritin_2 PF13668.6 AMK78553.1 - 0.017 15.3 0.2 0.022 14.9 0.2 1.4 1 1 0 1 1 1 0 Ferritin-like domain HTH_Crp_2 PF13545.6 AMK78554.1 - 3.5e-14 52.5 0.3 6.4e-14 51.7 0.3 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 AMK78554.1 - 0.00048 20.0 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 AMK78554.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator Crp PF00325.20 AMK78554.1 - 0.0017 17.9 0.0 0.0051 16.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family cNMP_binding PF00027.29 AMK78554.1 - 0.0039 17.2 0.2 0.0091 16.1 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain MarR PF01047.22 AMK78554.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 MarR family GntR PF00392.21 AMK78554.1 - 0.021 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_29 PF13551.6 AMK78554.1 - 0.023 14.7 0.1 0.053 13.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Fe_dep_repress PF01325.19 AMK78554.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AMK78554.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RepL PF05732.11 AMK78554.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) EF-hand_5 PF13202.6 AMK78556.1 - 1.8e-07 30.3 0.0 0.0095 15.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 AMK78556.1 - 5e-06 25.7 0.1 0.088 12.4 0.0 2.4 1 1 1 2 2 2 2 EF hand EF-hand_6 PF13405.6 AMK78556.1 - 6.9e-05 22.5 0.1 0.51 10.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 AMK78556.1 - 0.00066 20.1 0.1 1 9.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 AMK78556.1 - 0.007 16.7 0.1 0.27 11.6 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pyr_redox_2 PF07992.14 AMK78557.1 - 7.3e-71 238.8 0.2 9.1e-71 238.5 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AMK78557.1 - 1.1e-35 122.2 0.4 2.2e-35 121.2 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 AMK78557.1 - 2e-23 82.7 3.3 4.1e-21 75.3 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK78557.1 - 4.8e-18 65.5 0.9 7.7e-16 58.2 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AMK78557.1 - 1.4e-07 31.2 0.7 8.8e-07 28.6 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AMK78557.1 - 8.7e-07 28.0 2.1 0.023 13.4 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 AMK78557.1 - 1.2e-06 28.0 1.5 1.2e-06 28.0 1.5 2.6 2 2 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 AMK78557.1 - 3.8e-06 26.3 0.0 0.0002 20.7 0.0 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 AMK78557.1 - 4.5e-05 22.9 3.3 0.05 12.9 0.2 3.0 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 AMK78557.1 - 0.0034 16.5 5.7 0.0078 15.3 3.0 2.6 3 0 0 3 3 3 1 FAD binding domain XdhC_C PF13478.6 AMK78557.1 - 0.0054 17.2 0.8 0.48 10.9 0.0 2.7 3 0 0 3 3 3 1 XdhC Rossmann domain 3HCDH_N PF02737.18 AMK78557.1 - 0.0071 16.2 2.6 1.8 8.4 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 AMK78557.1 - 0.02 14.1 1.6 0.035 13.3 0.1 2.2 3 0 0 3 3 3 0 Thi4 family AdoHcyase_NAD PF00670.21 AMK78557.1 - 0.046 13.8 1.3 10 6.2 0.0 2.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 AMK78557.1 - 0.14 11.4 1.2 8.4 5.5 0.1 2.9 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 AMK78557.1 - 0.19 12.2 1.0 8.5 6.9 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AMK78557.1 - 0.32 10.4 1.9 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 AMK78557.1 - 0.67 10.2 8.3 0.39 11.0 2.4 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK78557.1 - 3.9 6.9 19.9 0.72 9.4 0.0 4.0 2 2 1 4 4 4 0 FAD dependent oxidoreductase Redoxin PF08534.10 AMK78558.1 - 8.2e-26 90.5 0.0 1e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AMK78558.1 - 1.8e-09 37.5 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF2383 PF09537.10 AMK78559.1 - 3.1e-10 40.4 0.0 6.2e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2383) YflT PF11181.8 AMK78560.1 - 6.9e-07 29.7 0.0 2.5e-06 27.9 0.0 1.9 2 1 0 2 2 2 1 Heat induced stress protein YflT Abhydrolase_1 PF00561.20 AMK78561.1 - 9.4e-28 97.6 0.2 4.5e-20 72.4 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AMK78561.1 - 4.5e-25 88.3 0.2 5e-16 58.7 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 AMK78561.1 - 4.3e-21 76.5 0.1 5e-21 76.3 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AMK78561.1 - 2e-09 37.3 0.1 2.3e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AMK78561.1 - 2.4e-06 27.5 0.0 0.003 17.4 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 AMK78561.1 - 1.2e-05 25.1 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 AMK78561.1 - 7.7e-05 22.6 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase AXE1 PF05448.12 AMK78561.1 - 0.0016 17.2 0.1 0.092 11.4 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 AMK78561.1 - 0.0063 16.1 0.0 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 AMK78561.1 - 0.022 14.7 0.2 0.4 10.6 0.2 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 AMK78561.1 - 0.029 14.0 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 AMK78561.1 - 0.036 13.0 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.13 AMK78561.1 - 0.037 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HAMP_N3 PF18575.1 AMK78561.1 - 0.055 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 HAMP N-terminal domain 3 DUF915 PF06028.11 AMK78561.1 - 0.056 12.8 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 AMK78561.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ndr PF03096.14 AMK78561.1 - 0.12 11.0 0.0 0.65 8.6 0.0 1.8 2 0 0 2 2 2 0 Ndr family DUF326 PF03860.16 AMK78562.1 - 0.011 15.7 38.5 0.059 13.4 8.2 4.4 4 0 0 4 4 4 0 Domain of Unknown Function (DUF326) CsbD PF05532.12 AMK78563.1 - 3.9e-09 36.3 8.4 4.8e-08 32.8 8.1 2.0 1 1 0 1 1 1 1 CsbD-like CsbD PF05532.12 AMK78564.1 - 3.9e-18 65.1 10.4 4.4e-18 64.9 10.4 1.1 1 0 0 1 1 1 1 CsbD-like ApoLp-III PF07464.11 AMK78564.1 - 0.015 15.4 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1418 PF07214.12 AMK78565.1 - 0.028 14.3 2.2 0.39 10.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) HTH_Crp_2 PF13545.6 AMK78566.1 - 1e-11 44.6 0.3 1e-11 44.6 0.3 2.4 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain Bac_export_3 PF01313.19 AMK78566.1 - 0.14 12.1 1.1 15 5.6 0.3 2.3 2 0 0 2 2 2 0 Bacterial export proteins, family 3 SMBP PF16785.5 AMK78567.1 - 1.3e-06 28.6 2.5 1.5e-06 28.4 2.5 1.0 1 0 0 1 1 1 1 Small metal-binding protein T6SS_VasJ PF16989.5 AMK78567.1 - 0.031 13.8 0.2 0.031 13.8 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ EAL PF00563.20 AMK78568.1 - 5.7e-17 62.0 0.2 4.1e-14 52.7 0.1 2.0 1 1 1 2 2 2 2 EAL domain RNA_helicase PF00910.22 AMK78568.1 - 0.19 12.1 0.0 5.2 7.5 0.0 2.0 1 1 1 2 2 2 0 RNA helicase HTH_Crp_2 PF13545.6 AMK78569.1 - 1.2e-14 54.0 0.4 1.2e-14 54.0 0.4 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AMK78569.1 - 2e-06 27.8 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MarR_2 PF12802.7 AMK78569.1 - 0.00076 19.3 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 MarR family GntR PF00392.21 AMK78569.1 - 0.016 14.9 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 AMK78569.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Fe_dep_repress PF01325.19 AMK78569.1 - 0.041 14.1 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RepL PF05732.11 AMK78569.1 - 0.24 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) SQHop_cyclase_C PF13243.6 AMK78570.1 - 1.6e-134 448.1 6.8 3.3e-132 440.5 4.0 2.5 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 AMK78570.1 - 3.7e-116 387.3 4.3 2e-107 358.6 0.1 4.4 3 2 1 4 4 4 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 AMK78570.1 - 1.8e-21 75.5 9.9 9.5e-06 25.2 0.0 7.5 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 AMK78570.1 - 1e-06 28.0 0.4 0.026 13.5 0.0 4.8 3 1 1 6 6 6 2 A-macroglobulin TED domain Pec_lyase PF09492.10 AMK78570.1 - 0.0044 16.4 1.4 0.35 10.2 0.1 3.7 5 0 0 5 5 5 1 Pectic acid lyase PAS_9 PF13426.7 AMK78572.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 AMK78572.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain DRMBL PF07522.14 AMK78572.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase DUF4398 PF14346.6 AMK78573.1 - 1.5e-14 54.4 26.3 2.3e-14 53.7 26.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) OmpA PF00691.20 AMK78574.1 - 6e-22 77.8 2.5 8.7e-22 77.3 0.1 2.2 2 0 0 2 2 2 1 OmpA family DUF4398 PF14346.6 AMK78574.1 - 2.1e-12 47.5 7.2 2.1e-12 47.5 7.2 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4398) CarboxypepD_reg PF13620.6 AMK78576.1 - 0.00037 20.7 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 AMK78576.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 SdrD B-like domain FlgD_ig PF13860.6 AMK78576.1 - 0.088 12.7 0.2 43 4.1 0.0 3.2 3 1 1 4 4 4 0 FlgD Ig-like domain Cupredoxin_1 PF13473.6 AMK78576.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Cupredoxin-like domain ACR_tran PF00873.19 AMK78577.1 - 6e-229 762.5 2.8 7.3e-229 762.2 2.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 AMK78577.1 - 2.2e-07 30.4 16.5 0.0053 16.2 12.4 2.4 2 0 0 2 2 2 2 Protein export membrane protein MMPL PF03176.15 AMK78577.1 - 0.00014 21.0 30.1 0.0017 17.4 15.1 2.6 2 0 0 2 2 2 2 MMPL family RELT PF12606.8 AMK78577.1 - 3 6.9 4.8 7.2 5.7 4.8 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 HlyD_D23 PF16576.5 AMK78578.1 - 0.0029 16.8 0.1 0.0057 15.9 0.1 1.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF4407 PF14362.6 AMK78578.1 - 0.0044 16.4 0.1 0.0057 16.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DctA-YdbH PF11739.8 AMK78578.1 - 0.0094 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Dicarboxylate transport OEP PF02321.18 AMK78578.1 - 0.39 10.5 6.0 0.69 9.7 6.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein OEP PF02321.18 AMK78579.1 - 5.6e-45 153.5 26.0 4.1e-24 85.4 15.6 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein Med29 PF11568.8 AMK78579.1 - 0.0094 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 29 HATPase_c PF02518.26 AMK78580.1 - 5.3e-21 75.2 0.0 9.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78580.1 - 7e-13 48.4 3.1 1.9e-12 47.0 3.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain 2CSK_N PF08521.10 AMK78580.1 - 1.1e-10 41.7 0.1 5.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HATPase_c_5 PF14501.6 AMK78580.1 - 0.00012 22.0 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AMK78580.1 - 0.0021 18.0 0.0 0.0074 16.2 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 AMK78581.1 - 3.3e-22 78.8 0.0 4.6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK78581.1 - 1.6e-20 72.9 0.0 5.1e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Glyco_transf_36 PF06165.11 AMK78582.1 - 1.9e-165 548.4 0.0 3.9e-83 278.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 36 Glyco_hydro_36 PF17167.4 AMK78582.1 - 1.2e-120 403.1 0.0 1.7e-120 402.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glycoamylase PF10091.9 AMK78582.1 - 4.7e-14 52.5 0.0 8.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Putative glucoamylase PEP-CTERM PF07589.11 AMK78584.1 - 0.0056 16.7 0.6 0.021 14.9 0.6 2.1 1 0 0 1 1 1 1 PEP-CTERM motif CsbD PF05532.12 AMK78585.1 - 2.2e-14 53.1 8.9 2.5e-14 52.9 8.9 1.0 1 0 0 1 1 1 1 CsbD-like CD20 PF04103.15 AMK78586.1 - 0.0072 16.4 2.2 0.012 15.7 2.2 1.4 1 1 0 1 1 1 1 CD20-like family DctQ PF04290.12 AMK78586.1 - 0.069 13.1 1.1 0.1 12.5 1.1 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Dynein_IC2 PF11540.8 AMK78586.1 - 0.11 12.5 1.8 2.7 8.0 0.6 2.3 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 DUF4342 PF14242.6 AMK78586.1 - 0.21 11.6 2.2 0.6 10.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF3464 PF11947.8 AMK78586.1 - 0.59 9.9 5.6 0.59 9.9 0.9 2.0 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 DUF202 PF02656.15 AMK78586.1 - 0.66 10.5 5.6 1.1 9.7 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Inhibitor_I68 PF10468.9 AMK78587.1 - 0.064 13.7 0.4 0.077 13.4 0.4 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 Phage_holin_3_6 PF07332.11 AMK78588.1 - 1.1e-08 35.1 4.5 1.5e-08 34.7 4.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF883 PF05957.13 AMK78589.1 - 5e-12 46.3 0.1 5.3e-12 46.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 AMK78589.1 - 3.6 8.2 6.1 0.36 11.4 1.7 1.6 2 0 0 2 2 2 0 YtxH-like protein BON PF04972.17 AMK78590.1 - 2.3e-21 75.9 0.4 2.8e-21 75.6 0.4 1.1 1 0 0 1 1 1 1 BON domain OmpA PF00691.20 AMK78591.1 - 1.1e-22 80.2 0.3 2.2e-22 79.2 0.3 1.5 1 0 0 1 1 1 1 OmpA family OMP_b-brl PF13505.6 AMK78591.1 - 3.1e-10 40.4 7.7 5.2e-10 39.7 7.7 1.3 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 AMK78591.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 OmpA-like transmembrane domain TSP_3 PF02412.18 AMK78591.1 - 0.22 11.2 4.8 0.46 10.2 4.8 1.5 1 0 0 1 1 1 0 Thrombospondin type 3 repeat UbiA PF01040.18 AMK78594.1 - 1.4e-20 73.7 22.9 2.4e-20 72.9 22.9 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family HAD PF12710.7 AMK78594.1 - 8.5e-11 42.6 0.1 9.9e-09 35.9 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK78594.1 - 6.3e-06 26.6 0.4 0.0046 17.3 0.0 2.7 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AMK78594.1 - 0.0041 17.2 0.2 0.12 12.5 0.0 2.1 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HTH_Tnp_1 PF01527.20 AMK78595.1 - 4.1e-06 27.0 0.1 4.6e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 AMK78595.1 - 0.00062 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Com_YlbF PF06133.11 AMK78595.1 - 0.045 14.4 0.0 0.053 14.1 0.0 1.1 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA HTH_Tnp_ISL3 PF13542.6 AMK78595.1 - 0.096 12.1 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ntox17 PF15524.6 AMK78595.1 - 0.12 12.6 0.1 0.53 10.6 0.1 1.8 1 1 1 2 2 2 0 Novel toxin 17 OmpA PF00691.20 AMK78596.1 - 2.8e-20 72.5 0.2 3.2e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 OmpA family Aconitase PF00330.20 AMK78597.1 - 2.5e-181 603.7 0.0 3.2e-181 603.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 AMK78597.1 - 7.1e-43 146.1 0.0 1.3e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Ferritin PF00210.24 AMK78598.1 - 2.3e-15 56.8 0.2 2.7e-15 56.6 0.2 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 AMK78598.1 - 0.077 13.4 0.1 3.2 8.2 0.3 2.0 2 0 0 2 2 2 0 Rubrerythrin Lyase_1 PF00206.20 AMK78599.1 - 7.7e-113 377.0 0.0 9.7e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AMK78599.1 - 1.4e-21 76.7 0.0 3.1e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus G-alpha PF00503.20 AMK78599.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Haem_degrading PF03928.14 AMK78600.1 - 6.9e-33 113.2 1.5 7.8e-33 113.1 1.5 1.0 1 0 0 1 1 1 1 Haem-degrading Prim_Zn_Ribbon PF08273.12 AMK78601.1 - 0.15 12.4 0.9 7.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF3290 PF11694.8 AMK78601.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Rubredoxin PF00301.20 AMK78601.1 - 1.1 9.4 6.2 12 6.1 0.2 3.8 4 0 0 4 4 4 0 Rubredoxin rve PF00665.26 AMK78602.1 - 0.091 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF4096 PF13340.6 AMK78603.1 - 1.7e-24 85.8 2.8 3.5e-24 84.8 2.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK78604.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK78604.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK78604.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK78604.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_22 PF13309.6 AMK78605.1 - 0.0086 16.1 0.3 0.066 13.3 0.1 2.2 2 0 0 2 2 2 1 HTH domain Phage_AlpA PF05930.12 AMK78605.1 - 0.026 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) FAM212 PF15342.6 AMK78605.1 - 1.9 8.3 4.9 10 6.0 0.0 3.2 4 0 0 4 4 4 0 FAM212 family RHH_8 PF17723.1 AMK78606.1 - 0.0025 18.0 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family VapB_antitoxin PF09957.9 AMK78606.1 - 0.0039 17.1 0.0 0.019 14.9 0.0 1.9 1 1 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB DUF3613 PF12266.8 AMK78606.1 - 0.023 14.4 0.1 0.13 12.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3613) CSN8_PSD8_EIF3K PF10075.9 AMK78606.1 - 0.057 13.4 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Cu-oxidase_4 PF02578.15 AMK78606.1 - 0.088 12.4 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase DUF2802 PF10975.8 AMK78606.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF3368 PF11848.8 AMK78607.1 - 0.00029 20.6 0.0 0.00064 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3368) PIN_4 PF13638.6 AMK78607.1 - 0.15 12.3 0.4 4.7 7.5 0.4 2.2 1 1 0 1 1 1 0 PIN domain IstB_IS21 PF01695.17 AMK78608.1 - 4.8e-56 189.3 0.0 6.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK78608.1 - 2e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK78608.1 - 4.1e-06 26.4 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AMK78608.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AMK78608.1 - 0.0068 15.3 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK78608.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AMK78608.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AMK78608.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AMK78608.1 - 0.031 14.5 0.5 0.28 11.5 0.3 2.1 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 AMK78608.1 - 0.031 13.3 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 AMK78608.1 - 0.044 13.5 0.2 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 AMK78608.1 - 0.05 13.5 1.6 0.87 9.5 0.0 2.5 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 AMK78608.1 - 0.054 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AMK78608.1 - 0.096 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AMK78608.1 - 0.11 12.9 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 AMK78608.1 - 0.12 12.1 0.3 0.33 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK78608.1 - 0.13 12.6 2.0 0.25 11.6 1.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK78608.1 - 0.17 11.9 0.3 0.47 10.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AMK78608.1 - 0.32 11.0 1.2 0.73 9.8 0.6 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TraF PF13728.6 AMK78609.1 - 3.5e-73 246.1 0.4 4.5e-73 245.8 0.4 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 AMK78609.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 AMK78609.1 - 0.15 12.6 0.1 0.58 10.6 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin-like domain DDE_Tnp_1_2 PF13586.6 AMK78610.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK78610.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK78610.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK78610.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4096 PF13340.6 AMK78611.1 - 6.7e-24 83.9 4.8 1.4e-23 82.9 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) ATP-grasp_3 PF02655.14 AMK78612.1 - 3.3e-18 66.2 0.0 4.7e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 AMK78612.1 - 0.00062 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.17 AMK78612.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 AMK78612.1 - 0.014 14.7 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 AMK78612.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus MCH PF02289.16 AMK78613.1 - 4.7e-133 443.3 0.0 5.3e-133 443.1 0.0 1.0 1 0 0 1 1 1 1 Cyclohydrolase (MCH) Tautomerase_2 PF14552.6 AMK78613.1 - 0.14 12.3 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Tautomerase enzyme RimK PF08443.11 AMK78614.1 - 2.4e-22 79.5 0.0 2.9e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Rimk_N PF18030.1 AMK78614.1 - 9e-08 32.4 0.0 5.2e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 RimK PreATP-grasp domain GSH-S_ATP PF02955.16 AMK78614.1 - 1.2e-07 31.3 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 AMK78614.1 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain R2K_3 PF14243.6 AMK78614.1 - 3.7e-05 23.8 0.2 5.7e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 ATPgrasp_YheCD PF14398.6 AMK78614.1 - 4.2e-05 22.9 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 2 YheC/D like ATP-grasp TTL PF03133.15 AMK78614.1 - 0.00039 19.6 0.0 0.23 10.5 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 AMK78614.1 - 0.0011 18.3 0.0 0.8 8.9 0.1 2.3 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AMK78614.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon R2K_2 PF18299.1 AMK78614.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 CitG PF01874.16 AMK78615.1 - 2e-55 188.4 0.3 2.4e-55 188.2 0.3 1.0 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase Fae PF08714.11 AMK78616.1 - 6.5e-69 230.9 2.5 7.3e-69 230.8 2.5 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) His_biosynth PF00977.21 AMK78617.1 - 1.4e-21 77.1 0.0 1.6e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein IGPS PF00218.21 AMK78617.1 - 0.21 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase ATP-grasp_3 PF02655.14 AMK78618.1 - 2.1e-27 96.2 0.0 2.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain preATP-grasp_3 PF18301.1 AMK78618.1 - 1.3e-12 47.7 0.4 2.5e-12 46.9 0.4 1.4 1 0 0 1 1 1 1 pre ATP-grasp 3 domain ATPgrasp_Ter PF15632.6 AMK78618.1 - 0.00051 19.8 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 AMK78618.1 - 0.0015 18.2 0.0 0.052 13.1 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 AMK78618.1 - 0.0021 17.4 0.0 0.0058 15.9 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Hydantoinase_A PF01968.18 AMK78619.1 - 1.4e-12 47.5 0.1 1.9e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase FtsA PF14450.6 AMK78619.1 - 0.027 14.9 0.3 0.12 12.8 0.2 2.2 2 1 0 2 2 2 0 Cell division protein FtsA Docking PF08990.11 AMK78619.1 - 0.46 10.1 1.9 0.69 9.6 0.5 2.1 2 0 0 2 2 2 0 Erythronolide synthase docking Chorismate_bind PF00425.18 AMK78620.1 - 1.2e-99 333.1 0.0 1.6e-99 332.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 AMK78620.1 - 3.2e-27 95.5 0.0 2.9e-24 85.9 0.0 2.9 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DUF1182 PF06681.13 AMK78620.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1182) R3H-assoc PF13902.6 AMK78620.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain AA_kinase PF00696.28 AMK78621.1 - 1.4e-12 47.7 0.8 4.1e-12 46.2 0.8 1.7 1 1 0 1 1 1 1 Amino acid kinase family DUF2959 PF11172.8 AMK78622.1 - 7.4e-73 244.8 8.0 8.5e-73 244.6 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) AKNA PF12443.8 AMK78622.1 - 0.0013 19.3 3.7 0.35 11.5 0.6 2.7 1 1 1 2 2 2 2 AT-hook-containing transcription factor LXG PF04740.12 AMK78622.1 - 0.0076 16.0 5.8 0.03 14.0 0.1 2.9 2 1 1 3 3 3 1 LXG domain of WXG superfamily FapA PF03961.13 AMK78622.1 - 0.067 11.8 2.3 0.077 11.6 2.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Helicase_IV_N PF12462.8 AMK78622.1 - 0.11 12.4 4.4 0.25 11.3 4.2 1.8 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal W2 PF02020.18 AMK78622.1 - 0.23 11.6 2.6 0.26 11.5 0.8 2.0 3 0 0 3 3 3 0 eIF4-gamma/eIF5/eIF2-epsilon DUF1664 PF07889.12 AMK78622.1 - 0.37 10.8 2.6 1.3 9.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 AMK78622.1 - 0.39 10.8 11.1 0.37 10.9 8.4 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF3347 PF11827.8 AMK78622.1 - 0.86 9.8 5.4 1.6 8.9 1.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3347) ATP-synt_D PF01813.17 AMK78622.1 - 0.87 9.4 10.4 6 6.6 0.1 3.3 1 1 0 2 2 2 0 ATP synthase subunit D DUF5304 PF17230.2 AMK78623.1 - 0.057 13.7 0.1 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5304) MMR_HSR1 PF01926.23 AMK78624.1 - 1.7e-08 34.5 0.0 5.2e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 AMK78624.1 - 0.00017 21.2 0.0 0.01 15.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AMK78624.1 - 0.00041 20.4 0.1 0.013 15.6 0.1 2.7 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 AMK78624.1 - 0.0092 16.4 0.7 0.26 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 AMK78624.1 - 0.022 14.7 0.2 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Nuc_deoxyri_tr2 PF15891.5 AMK78624.1 - 0.19 12.0 2.1 0.63 10.4 0.0 2.7 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like DUF87 PF01935.17 AMK78624.1 - 0.81 9.7 2.5 36 4.3 0.0 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 AMK78625.1 - 7.7e-08 32.4 0.0 2.5e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AMK78625.1 - 2.7e-06 27.5 0.1 0.0062 16.6 0.0 2.8 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 AMK78625.1 - 1.5e-05 25.0 0.0 0.0001 22.3 0.0 2.3 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 AMK78625.1 - 0.0019 18.7 0.2 0.0082 16.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 AMK78625.1 - 0.0039 17.5 1.2 0.4 11.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 AMK78625.1 - 0.012 16.0 14.7 0.017 15.5 0.0 4.1 3 1 0 3 3 3 0 AAA ATPase domain GlutR_dimer PF00745.20 AMK78625.1 - 0.043 14.3 0.5 0.043 14.3 0.5 2.8 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Torsin PF06309.11 AMK78625.1 - 0.063 13.4 0.4 0.88 9.7 0.0 2.6 3 0 0 3 3 3 0 Torsin AAA_28 PF13521.6 AMK78625.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.6 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 AMK78625.1 - 0.15 12.3 0.1 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 AMK78625.1 - 9.5 6.7 9.4 29 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain PAS_3 PF08447.12 AMK78626.1 - 1.2e-75 249.8 1.3 4.1e-16 59.0 0.0 7.0 7 0 0 7 7 7 6 PAS fold PAS PF00989.25 AMK78626.1 - 2.7e-49 165.9 1.3 3.5e-12 46.3 0.0 7.6 7 0 0 7 7 7 7 PAS fold PAS_4 PF08448.10 AMK78626.1 - 4e-46 155.8 5.1 1.2e-11 44.8 0.1 6.7 6 0 0 6 6 6 5 PAS fold PAS_9 PF13426.7 AMK78626.1 - 2.8e-37 127.1 0.0 3e-08 33.9 0.0 6.4 6 0 0 6 6 6 4 PAS domain HATPase_c PF02518.26 AMK78626.1 - 4.6e-30 104.4 0.1 9.8e-30 103.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK78626.1 - 4.1e-27 94.6 0.2 9.6e-27 93.4 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_8 PF13188.7 AMK78626.1 - 1.1e-21 76.4 0.3 0.0002 21.3 0.0 5.2 5 0 0 5 5 4 4 PAS domain HisKA PF00512.25 AMK78626.1 - 9.2e-18 64.0 1.7 4.3e-17 61.9 0.1 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF4118 PF13493.6 AMK78626.1 - 1.1e-16 60.5 9.5 2e-16 59.7 9.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) PAS_11 PF14598.6 AMK78626.1 - 7.6e-08 32.5 0.0 0.62 10.2 0.0 5.0 5 0 0 5 5 5 2 PAS domain SPC25 PF06703.11 AMK78626.1 - 0.035 13.9 0.2 0.063 13.1 0.2 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UPF0029 PF01205.19 AMK78626.1 - 0.1 12.9 0.0 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein family UPF0029 HATPase_c_3 PF13589.6 AMK78626.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_holin_3_6 PF07332.11 AMK78626.1 - 0.3 11.2 2.0 0.87 9.6 2.0 1.8 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Response_reg PF00072.24 AMK78627.1 - 1.2e-51 173.6 4.6 1.3e-25 89.7 0.1 3.2 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 AMK78627.1 - 4.9e-25 88.2 0.0 1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78627.1 - 1.3e-14 54.0 0.1 1.3e-14 54.0 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AMK78627.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EAP30 PF04157.16 AMK78627.1 - 0.41 9.9 3.4 0.67 9.2 3.4 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Uso1_p115_C PF04871.13 AMK78627.1 - 0.46 10.8 4.6 1 9.8 4.6 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1635 PF07795.11 AMK78627.1 - 0.58 10.0 4.7 0.15 11.9 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) GGDEF PF00990.21 AMK78628.1 - 1.1e-50 171.5 0.0 1.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK78628.1 - 6.5e-26 90.7 0.0 1.5e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GGDEF_2 PF17853.1 AMK78628.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.7 1 1 0 1 1 1 0 GGDEF-like domain COX1 PF00115.20 AMK78630.1 - 3.3e-63 214.1 67.1 3.8e-63 213.8 67.1 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cytochrom_C PF00034.21 AMK78631.1 - 9.3e-10 39.5 0.1 6.8e-09 36.8 0.0 2.0 1 1 1 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AMK78631.1 - 9.1e-07 29.1 0.1 0.00013 22.2 0.0 2.4 1 1 1 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III SecD_SecF PF02355.16 AMK78632.1 - 0.056 12.8 4.6 0.071 12.5 4.6 1.1 1 0 0 1 1 1 0 Protein export membrane protein DUF3792 PF12670.7 AMK78632.1 - 0.078 13.1 7.0 0.1 12.8 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF2631 PF10939.8 AMK78632.1 - 0.084 12.7 0.5 0.17 11.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) FUSC PF04632.12 AMK78632.1 - 2 6.8 7.7 2.5 6.6 7.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PsbX PF06596.11 AMK78632.1 - 3.7 7.6 8.6 0.14 12.1 2.4 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Rrf2 PF02082.20 AMK78633.1 - 1.2e-25 89.7 0.1 3.6e-25 88.1 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulator GntR PF00392.21 AMK78633.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 AMK78633.1 - 0.00028 20.7 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_6 PF01418.17 AMK78633.1 - 0.00039 20.4 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 AMK78633.1 - 0.00081 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 AMK78633.1 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AMK78633.1 - 0.0022 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_17 PF12728.7 AMK78633.1 - 0.003 17.7 0.0 0.0051 17.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AMK78633.1 - 0.0044 17.0 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 AMK78633.1 - 0.0083 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain PuR_N PF09182.10 AMK78633.1 - 0.02 14.8 1.4 0.18 11.7 1.4 2.3 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal HTH_AraC PF00165.23 AMK78633.1 - 0.034 14.2 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Lactamase_B PF00753.27 AMK78634.1 - 3e-29 102.4 0.3 3.4e-29 102.3 0.3 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK78634.1 - 3e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AMK78634.1 - 0.021 14.7 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PDEase_II PF02112.15 AMK78634.1 - 0.056 12.6 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Lactamase_B_6 PF16661.5 AMK78634.1 - 0.091 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain 2-oxoacid_dh PF00198.23 AMK78635.1 - 3.1e-81 272.2 0.0 4.2e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 AMK78635.1 - 2.3e-18 65.8 0.1 4.1e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 AMK78635.1 - 2.7e-13 50.0 0.3 6.1e-13 48.9 0.3 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 AMK78635.1 - 7.7e-07 28.8 0.9 0.0003 20.5 0.9 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 AMK78635.1 - 0.013 15.4 0.1 0.044 13.7 0.1 1.9 2 0 0 2 2 2 0 Glycine cleavage H-protein HlyD_3 PF13437.6 AMK78635.1 - 0.016 15.9 1.8 0.51 11.1 0.0 3.0 2 2 1 3 3 3 0 HlyD family secretion protein QRPTase_N PF02749.16 AMK78635.1 - 0.11 12.6 0.1 15 5.8 0.1 2.4 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain RnfC_N PF13375.6 AMK78635.1 - 0.15 12.0 0.1 18 5.4 0.0 2.6 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Transket_pyr PF02779.24 AMK78636.1 - 2.6e-62 209.7 0.0 4.9e-62 208.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 AMK78636.1 - 5.7e-55 186.4 0.0 1e-54 185.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 AMK78636.1 - 6.2e-48 162.4 0.0 1e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 AMK78636.1 - 1.4e-13 50.2 0.2 3e-13 49.1 0.2 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PFOR_II PF17147.4 AMK78636.1 - 0.059 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF2914 PF11141.8 AMK78637.1 - 7.3e-14 51.3 1.0 1.4e-13 50.4 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2914) FixH PF05751.11 AMK78637.1 - 0.0027 17.7 0.3 1.8 8.6 0.1 2.2 2 0 0 2 2 2 2 FixH Histone_HNS PF00816.21 AMK78638.1 - 2.8e-23 82.6 2.2 3.2e-23 82.4 2.2 1.0 1 0 0 1 1 1 1 H-NS histone family LcrG PF07216.12 AMK78638.1 - 0.036 14.0 0.3 0.14 12.1 0.2 1.9 2 0 0 2 2 2 0 LcrG protein DUF4054 PF13262.6 AMK78638.1 - 0.063 13.3 0.7 0.31 11.1 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4054) Tli4_N PF18443.1 AMK78638.1 - 0.084 13.2 0.1 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Abhydrolase_6 PF12697.7 AMK78639.1 - 2e-11 44.9 3.4 2.4e-11 44.7 3.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK78639.1 - 2.6e-10 40.0 0.0 3.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AMK78639.1 - 6.1e-09 35.9 0.0 2.5e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 AMK78639.1 - 0.034 14.0 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase YopE_N PF09020.10 AMK78639.1 - 0.22 11.8 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 YopE, N terminal Peptidase_M14 PF00246.24 AMK78640.1 - 1.6e-14 54.4 0.0 2.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 AMK78640.1 - 4.1e-08 33.0 0.0 0.00042 19.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 AMK78640.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Fe_dep_repr_C PF02742.15 AMK78640.1 - 0.1 12.7 0.7 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Acetyltransf_5 PF13444.6 AMK78641.1 - 1.7e-21 76.8 0.0 3.5e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyltransferase PF01553.21 AMK78641.1 - 6.9e-10 38.7 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase zinc_ribbon_5 PF13719.6 AMK78641.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TFIIS_M PF07500.14 AMK78641.1 - 0.097 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain FAD_binding_2 PF00890.24 AMK78643.1 - 1.5e-99 334.0 0.2 1.8e-99 333.6 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AMK78643.1 - 8.5e-16 58.1 0.0 3.1e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 AMK78643.1 - 2.5e-07 30.2 2.1 0.008 15.4 0.8 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK78643.1 - 6.8e-06 25.9 3.4 1.8e-05 24.5 3.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AMK78643.1 - 0.05 12.9 1.4 0.33 10.1 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Sigma70_r4_2 PF08281.12 AMK78644.1 - 4.7e-19 67.8 0.2 1.1e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 AMK78644.1 - 5.6e-19 67.7 0.6 1.3e-18 66.5 0.6 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK78644.1 - 9.6e-12 44.2 0.2 1.6e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AMK78644.1 - 2.5e-09 37.3 0.7 6.4e-09 36.0 0.7 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AMK78644.1 - 0.00024 20.8 0.0 0.00075 19.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_16 PF12645.7 AMK78644.1 - 0.00032 20.7 0.1 0.00068 19.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_antitermQ PF06530.12 AMK78644.1 - 0.021 14.7 0.3 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Phage antitermination protein Q GerE PF00196.19 AMK78644.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family RseA_N PF03872.13 AMK78645.1 - 1.8e-10 41.2 1.3 3e-10 40.4 0.3 1.8 2 0 0 2 2 2 1 Anti sigma-E protein RseA, N-terminal domain MEDS PF14417.6 AMK78645.1 - 0.03 14.1 0.3 0.11 12.4 0.1 1.8 1 1 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MucB_RseB PF03888.14 AMK78646.1 - 1.3e-51 174.6 0.3 2.1e-51 174.0 0.3 1.3 1 0 0 1 1 1 1 MucB/RseB N-terminal domain MucB_RseB_C PF17188.4 AMK78646.1 - 1.3e-20 73.4 0.0 2.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 MucB/RseB C-terminal domain LolA_like PF17131.4 AMK78646.1 - 1.4e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Outer membrane lipoprotein-sorting protein YtfJ_HI0045 PF09695.10 AMK78646.1 - 0.032 13.9 0.2 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) DUF1571 PF07608.11 AMK78646.1 - 0.044 13.2 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Mak10 PF04112.13 AMK78646.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase POTRA_2 PF08479.11 AMK78646.1 - 0.11 12.4 0.0 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 POTRA domain, ShlB-type Trypsin_2 PF13365.6 AMK78647.1 - 1.8e-34 119.8 0.5 3.1e-34 119.1 0.5 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AMK78647.1 - 1.1e-26 92.9 2.6 1e-16 61.0 0.1 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 AMK78647.1 - 2.6e-19 68.8 6.2 2e-11 43.6 0.2 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 AMK78647.1 - 2.1e-18 66.4 7.0 1.2e-10 41.5 0.6 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 AMK78647.1 - 1.4e-15 57.8 0.0 2.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 AMK78647.1 - 1.8e-06 27.0 0.6 0.028 13.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 PDZ_1 PF12812.7 AMK78647.1 - 2.5e-06 27.4 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 PDZ-like domain Peptidase_S29 PF02907.15 AMK78647.1 - 0.083 12.6 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease LSM PF01423.22 AMK78647.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 LSM domain PALP PF00291.25 AMK78648.1 - 2.1e-71 240.8 4.3 2.3e-71 240.6 4.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2315 PF10231.9 AMK78649.1 - 0.075 13.1 3.4 0.73 9.9 0.9 2.5 2 0 0 2 2 2 0 Apoptogenic protein 1 DUF2207 PF09972.9 AMK78649.1 - 1.5 7.5 10.5 0.88 8.3 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF148 PF02520.17 AMK78649.1 - 6.7 6.9 12.2 0.81 9.8 1.8 3.6 3 1 1 4 4 4 0 Domain of unknown function DUF148 DUF4732 PF15876.5 AMK78650.1 - 0.029 14.5 0.2 0.051 13.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) FtsX_ECD PF18075.1 AMK78650.1 - 2.4 8.8 8.9 2.7 8.7 6.6 2.4 2 1 0 2 2 2 0 FtsX extracellular domain DUF4136 PF13590.6 AMK78651.1 - 0.0025 18.4 0.1 0.0038 17.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4136) DUF3391 PF11871.8 AMK78653.1 - 3e-19 69.9 0.1 5.3e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HD PF01966.22 AMK78653.1 - 3.9e-16 59.4 0.1 6.7e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AMK78653.1 - 2e-14 53.6 0.0 4.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 HD domain HATPase_c PF02518.26 AMK78654.1 - 3.6e-24 85.4 0.2 8.4e-24 84.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78654.1 - 5.9e-11 42.3 0.1 5.9e-11 42.3 0.1 3.5 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 AMK78654.1 - 4.5e-09 36.5 1.5 2.5e-07 30.9 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 AMK78654.1 - 1.2e-08 34.7 1.1 0.0071 16.4 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_9 PF13426.7 AMK78654.1 - 2.4e-08 34.1 0.4 0.0034 17.6 0.0 3.6 3 1 0 3 3 3 2 PAS domain PAS PF00989.25 AMK78654.1 - 2.5e-07 30.7 4.5 0.0016 18.4 0.1 4.5 4 1 1 5 5 5 2 PAS fold HATPase_c_5 PF14501.6 AMK78654.1 - 0.00015 21.6 0.0 0.00066 19.6 0.0 2.0 2 0 0 2 2 2 1 GHKL domain PAS_4 PF08448.10 AMK78654.1 - 0.00035 20.8 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 AMK78654.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AMK78654.1 - 0.0065 16.7 0.0 0.63 10.4 0.0 3.4 2 1 0 2 2 2 1 PAS fold PAS_12 PF18095.1 AMK78654.1 - 0.052 13.2 1.2 0.69 9.5 0.0 2.7 3 0 0 3 3 3 0 UPF0242 C-terminal PAS-like domain HATPase_c_2 PF13581.6 AMK78654.1 - 0.06 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Sec34 PF04136.15 AMK78654.1 - 3.5 7.5 6.7 9.6 6.1 3.5 2.6 2 1 0 2 2 2 0 Sec34-like family Phage_Mu_Gam PF07352.12 AMK78654.1 - 9.6 6.1 10.2 13 5.7 3.6 3.4 4 0 0 4 4 4 0 Bacteriophage Mu Gam like protein PNTB PF02233.16 AMK78655.1 - 1.8e-194 647.0 22.0 2e-194 646.8 22.0 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 AMK78655.1 - 0.0086 15.8 0.3 0.13 12.0 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Phage_holin_2_4 PF16082.5 AMK78655.1 - 0.086 12.6 0.4 0.086 12.6 0.4 2.7 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like AlaDh_PNT_C PF01262.21 AMK78656.1 - 4.7e-76 254.8 2.5 4.7e-76 254.8 2.5 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 AMK78656.1 - 2.5e-49 167.0 1.6 4.4e-49 166.3 0.5 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 AMK78656.1 - 2.6e-36 123.9 6.3 2.6e-36 123.9 6.3 1.9 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 AMK78656.1 - 6.5e-07 28.9 1.7 0.014 14.8 0.1 3.8 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3392 PF11872.8 AMK78656.1 - 0.0016 18.7 2.1 0.0042 17.3 2.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) Pyr_redox PF00070.27 AMK78656.1 - 0.067 13.8 0.7 0.38 11.4 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AMK78656.1 - 0.27 10.4 2.7 0.56 9.4 2.7 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GGDEF PF00990.21 AMK78657.1 - 9.3e-48 162.0 0.0 1.6e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK78657.1 - 2.3e-27 95.4 0.0 5.4e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain OEP PF02321.18 AMK78657.1 - 0.015 15.1 1.4 0.99 9.2 0.2 2.9 3 0 0 3 3 3 0 Outer membrane efflux protein GGDEF_2 PF17853.1 AMK78657.1 - 0.02 15.2 0.0 0.052 13.8 0.0 1.8 2 0 0 2 2 2 0 GGDEF-like domain NTP_transf_2 PF01909.23 AMK78658.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain HAD_2 PF13419.6 AMK78659.1 - 3.3e-19 69.7 0.0 4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK78659.1 - 1.4e-09 38.6 0.0 4.1e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AMK78659.1 - 4.7e-05 23.4 0.0 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4918 PF16265.5 AMK78659.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) GHMP_kinases_N PF00288.26 AMK78660.1 - 4.4e-09 36.5 1.7 5.9e-09 36.0 0.3 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 AMK78660.1 - 7.1e-06 26.3 0.1 1.4e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal SoxZ PF08770.11 AMK78661.1 - 1.2e-32 111.6 0.0 1.3e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ DUF1508 PF07411.12 AMK78661.1 - 0.19 11.6 0.8 7.2 6.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1508) SoxY PF13501.6 AMK78662.1 - 5.7e-28 97.4 0.0 7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Sulfur oxidation protein SoxY DUF2249 PF10006.9 AMK78662.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Spore_YhaL PF14147.6 AMK78663.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YhaL PNP_UDP_1 PF01048.20 AMK78664.1 - 5.4e-41 140.4 0.6 6.3e-41 140.1 0.6 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pribosyltran PF00156.27 AMK78665.1 - 1.6e-19 70.0 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 AMK78665.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Glyco_hydro_3 PF00933.21 AMK78666.1 - 1.8e-77 260.9 0.0 2.4e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain FliL PF03748.14 AMK78667.1 - 1.8e-18 67.0 0.4 2.5e-18 66.6 0.4 1.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL Defensin_propep PF00879.18 AMK78667.1 - 0.0083 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Defensin propeptide SSF PF00474.17 AMK78667.1 - 0.0095 14.8 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2975 PF11188.8 AMK78668.1 - 0.00033 20.6 0.3 0.00033 20.6 0.3 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2975) DoxX_2 PF13564.6 AMK78668.1 - 0.12 12.5 2.0 0.17 12.0 0.1 2.2 2 1 1 3 3 3 0 DoxX-like family HIT PF01230.23 AMK78669.1 - 4e-12 46.7 0.0 5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain Autotransporter PF03797.19 AMK78670.1 - 4e-56 190.5 31.2 5.8e-56 190.0 31.2 1.2 1 0 0 1 1 1 1 Autotransporter beta-domain Peptidase_M74 PF03411.13 AMK78671.1 - 1.7e-96 322.4 0.0 2e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Penicillin-insensitive murein endopeptidase Acyl_transf_3 PF01757.22 AMK78672.1 - 2.5e-21 76.1 32.4 4.6e-21 75.2 32.4 1.4 1 1 0 1 1 1 1 Acyltransferase family DEAD PF00270.29 AMK78673.1 - 1.8e-47 161.3 0.0 7.4e-47 159.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK78673.1 - 1.2e-33 115.8 0.0 3e-31 108.0 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DbpA PF03880.15 AMK78673.1 - 8.9e-26 89.7 0.2 1.7e-25 88.8 0.2 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 AMK78673.1 - 4.1e-09 36.7 0.0 6.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 AMK78673.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 AMK78673.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 1 0 1 1 1 0 Helicase AAA_22 PF13401.6 AMK78673.1 - 0.19 12.0 0.4 0.65 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain Methyltransf_25 PF13649.6 AMK78675.1 - 1.9e-14 54.1 0.0 1.1e-13 51.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78675.1 - 1.4e-12 48.1 0.0 5.5e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK78675.1 - 1.6e-09 37.8 0.0 2.7e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK78675.1 - 1.8e-08 34.3 0.0 4.2e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78675.1 - 5.3e-07 30.3 0.0 2.5e-06 28.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain TehB PF03848.14 AMK78675.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 AMK78675.1 - 0.21 11.2 0.0 0.48 10.0 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) EF_assoc_2 PF08356.12 AMK78676.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 EF hand associated Y1_Tnp PF01797.16 AMK78677.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase IS200 like Peptidase_C14 PF00656.22 AMK78678.1 - 1e-13 51.8 1.2 4.2e-13 49.8 1.2 1.9 1 1 0 1 1 1 1 Caspase domain DUF2130 PF09903.9 AMK78679.1 - 9.3e-74 247.9 0.0 9.3e-74 247.9 0.0 3.0 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2130) VEG PF06257.11 AMK78679.1 - 2 8.5 4.7 11 6.2 0.6 2.6 2 0 0 2 2 2 0 Biofilm formation stimulator VEG Sulfate_transp PF00916.20 AMK78680.1 - 8.6e-56 189.3 20.9 1.3e-55 188.7 20.9 1.2 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 AMK78680.1 - 4.8e-07 30.2 8.7 7.5e-06 26.3 0.4 5.0 4 2 1 5 5 5 2 Molybdate transporter of MFS superfamily STAS PF01740.21 AMK78680.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 AMK78680.1 - 0.003 17.9 0.0 0.0065 16.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain SieB PF14163.6 AMK78680.1 - 0.036 13.6 3.5 1.2 8.6 1.3 3.3 3 0 0 3 3 3 0 Super-infection exclusion protein B GHL13 PF14883.6 AMK78681.1 - 3.5e-130 433.8 0.7 4.7e-130 433.4 0.7 1.2 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 Polysacc_deac_1 PF01522.21 AMK78681.1 - 1.6e-29 102.3 0.1 1.1e-28 99.6 0.0 2.3 3 0 0 3 3 3 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 AMK78681.1 - 0.0014 17.9 0.1 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 GHL10 PF02638.15 AMK78681.1 - 0.025 13.7 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Glyco_tranf_2_3 PF13641.6 AMK78682.1 - 1.8e-35 122.9 0.0 2.3e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AMK78682.1 - 1.3e-31 109.7 0.0 2.2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AMK78682.1 - 1.4e-27 97.0 8.9 1.4e-27 97.0 8.9 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 AMK78682.1 - 5e-12 45.6 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 AMK78682.1 - 4e-10 38.9 0.0 9.9e-06 24.4 0.0 3.1 2 1 1 3 3 3 3 Chitin synthase Glyco_tranf_2_2 PF10111.9 AMK78682.1 - 5.2e-06 26.1 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 AMK78682.1 - 0.0076 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PgaD PF13994.6 AMK78683.1 - 2.7e-23 82.7 5.5 3.1e-23 82.5 5.5 1.1 1 0 0 1 1 1 1 PgaD-like protein Yip1 PF04893.17 AMK78683.1 - 8.3 6.1 15.9 16 5.1 15.9 1.5 1 1 0 1 1 1 0 Yip1 domain ACT_6 PF13740.6 AMK78684.1 - 3.8e-11 42.8 0.4 3.4e-10 39.8 0.1 2.0 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AMK78684.1 - 0.0023 18.5 0.1 0.37 11.4 0.1 2.2 2 0 0 2 2 2 2 ACT domain CENP-L PF13092.6 AMK78684.1 - 0.032 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 ACT PF01842.25 AMK78684.1 - 0.064 13.0 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 ACT domain AhpC-TSA PF00578.21 AMK78685.1 - 9.3e-34 116.0 0.1 1.1e-33 115.8 0.1 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK78685.1 - 1.1e-16 60.9 0.0 1.3e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 AMK78685.1 - 0.032 13.8 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.6 AMK78685.1 - 0.08 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like OAD_gamma PF04277.13 AMK78686.1 - 2e-14 53.9 4.1 3.5e-14 53.1 4.1 1.4 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain HMGL-like PF00682.19 AMK78687.1 - 1.6e-57 195.0 0.1 2.8e-57 194.3 0.1 1.3 1 0 0 1 1 1 1 HMGL-like PYC_OADA PF02436.18 AMK78687.1 - 2.4e-55 187.3 0.0 4.8e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_lipoyl PF00364.22 AMK78687.1 - 3.5e-15 55.6 4.7 3.5e-15 55.6 4.7 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 AMK78687.1 - 3.7e-09 36.3 6.2 1e-05 25.2 2.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AMK78687.1 - 7.2e-05 23.4 5.5 0.064 14.0 0.6 3.1 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK78687.1 - 0.00043 19.6 1.2 0.21 10.8 0.2 2.6 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2118 PF09891.9 AMK78687.1 - 0.0067 16.4 0.7 0.016 15.1 0.7 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) TAL_FSA PF00923.19 AMK78687.1 - 0.11 11.8 0.1 0.28 10.5 0.1 1.6 2 0 0 2 2 2 0 Transaldolase/Fructose-6-phosphate aldolase GCV_H PF01597.19 AMK78687.1 - 0.29 11.0 3.0 0.43 10.5 1.0 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein OAD_beta PF03977.13 AMK78688.1 - 4.7e-158 525.7 31.9 5.4e-158 525.5 31.9 1.0 1 0 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit Glycos_transf_1 PF00534.20 AMK78689.1 - 7.3e-47 159.1 0.1 1.4e-46 158.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK78689.1 - 1.3e-31 109.8 0.0 5.9e-31 107.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK78689.1 - 4.6e-14 52.8 0.4 1.2e-13 51.4 0.3 1.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AMK78689.1 - 2.7e-12 47.4 1.0 4.9e-12 46.6 1.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AMK78689.1 - 1.5e-07 31.5 0.1 1.5e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 AMK78689.1 - 5.9e-06 26.6 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 GLF PF03275.13 AMK78690.1 - 2e-52 177.9 0.1 2.7e-52 177.5 0.1 1.1 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 AMK78690.1 - 7.4e-15 54.9 0.1 1.4e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK78690.1 - 1.8e-06 27.8 0.4 3.1e-06 27.0 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 AMK78690.1 - 1.3e-05 25.3 0.0 4.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 AMK78690.1 - 8.4e-05 21.9 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AMK78690.1 - 0.00022 21.2 0.0 0.00054 19.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 AMK78690.1 - 0.00042 20.8 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AMK78690.1 - 0.0034 16.7 0.0 0.0085 15.4 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Sacchrp_dh_NADP PF03435.18 AMK78690.1 - 0.0039 17.4 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 AMK78690.1 - 0.0045 16.1 0.5 0.0062 15.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 AMK78690.1 - 0.0066 15.7 0.1 0.0097 15.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 AMK78690.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 AMK78690.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 AMK78690.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 AMK78690.1 - 0.013 15.0 0.1 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1188 PF06690.11 AMK78690.1 - 0.058 12.9 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) ThiF PF00899.21 AMK78690.1 - 0.076 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 AMK78690.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 AMK78690.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 AMK78690.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 AMK78690.1 - 0.2 11.2 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 AMK78690.1 - 0.29 9.8 0.2 0.41 9.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyco_trans_1_4 PF13692.6 AMK78691.1 - 5.8e-11 43.0 0.0 8.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AMK78691.1 - 7.6e-09 35.3 0.0 3.3e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK78691.1 - 0.00097 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AMK78691.1 - 0.0053 17.1 0.0 0.0097 16.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 HEPN PF05168.14 AMK78692.1 - 0.084 13.0 0.4 5.5 7.2 0.4 2.1 1 1 1 2 2 2 0 HEPN domain NTP_transf_2 PF01909.23 AMK78693.1 - 4.2e-06 27.0 0.1 4.3e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 AMK78693.1 - 2.1e-05 24.5 0.5 2.2e-05 24.4 0.5 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 AMK78693.1 - 0.024 14.8 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase beta palm Glyco_tranf_2_3 PF13641.6 AMK78694.1 - 5.8e-21 75.4 0.0 8.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 AMK78694.1 - 8.9e-18 64.7 0.0 1.9e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 AMK78694.1 - 4.6e-06 26.7 0.1 1.2e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AMK78694.1 - 0.037 14.5 0.0 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 AMK78694.1 - 0.06 12.8 0.0 0.32 10.4 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 HAD_2 PF13419.6 AMK78695.1 - 9.1e-05 22.6 0.2 0.00035 20.7 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SMK-1 PF04802.15 AMK78695.1 - 0.0095 15.8 0.4 0.22 11.4 0.1 2.6 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 PYRIN PF02758.16 AMK78695.1 - 0.093 12.9 0.4 0.26 11.5 0.4 1.7 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Glycos_transf_1 PF00534.20 AMK78696.1 - 5.3e-21 74.9 0.0 6.8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK78696.1 - 5.7e-19 68.9 0.0 7.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AMK78696.1 - 4.5e-09 36.6 0.0 7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AMK78697.1 - 5.4e-20 71.9 0.1 8.1e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AMK78697.1 - 2.3e-09 37.1 1.0 7.5e-09 35.4 1.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 AMK78697.1 - 6.7e-08 32.7 0.0 9.8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 AMK78697.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family Glyco_transf_11 PF01531.16 AMK78698.1 - 1.9e-37 129.1 7.8 2.6e-37 128.7 7.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 Glyco_transf_6 PF03414.13 AMK78699.1 - 1.4e-28 99.6 4.2 2.4e-28 98.8 3.9 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 6 LPD15 PF18828.1 AMK78699.1 - 0.045 13.6 0.8 0.79 9.6 0.0 2.3 1 1 1 2 2 2 0 Large polyvalent-protein-associated domain 15 Methyltransf_31 PF13847.6 AMK78700.1 - 0.00019 21.3 0.1 0.00025 20.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK78700.1 - 0.0033 17.3 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78700.1 - 0.012 16.3 0.0 0.019 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78700.1 - 0.036 14.8 0.2 0.071 13.9 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain ZnuA PF01297.17 AMK78700.1 - 0.16 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Methyltransf_25 PF13649.6 AMK78700.1 - 0.21 12.3 0.0 0.38 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 AMK78701.1 - 1.8e-22 80.3 0.1 9.2e-22 78.0 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Wzt_C PF14524.6 AMK78701.1 - 2.7e-06 27.5 0.3 5.6e-06 26.4 0.3 1.5 1 0 0 1 1 1 1 Wzt C-terminal domain AAA_21 PF13304.6 AMK78701.1 - 3.2e-06 27.2 2.7 0.00019 21.4 0.7 2.6 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK78701.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AMK78701.1 - 0.0027 17.5 2.9 0.0088 15.8 2.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 AMK78701.1 - 0.0035 17.9 0.8 0.011 16.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AMK78701.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 AMK78701.1 - 0.018 15.1 1.2 0.038 14.1 0.4 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AMK78701.1 - 0.099 12.3 0.1 0.29 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 AMK78701.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.19 AMK78701.1 - 0.15 11.5 1.3 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 AMK78702.1 - 1.5e-25 89.9 23.4 2.1e-25 89.4 23.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AMK78702.1 - 0.0024 17.1 22.8 0.0024 17.1 22.8 2.0 1 1 0 2 2 2 1 ABC-2 family transporter protein Radical_SAM_N PF08497.10 AMK78703.1 - 2.3e-142 473.6 0.0 3.2e-142 473.1 0.0 1.2 1 0 0 1 1 1 1 Radical SAM N-terminal DUF3362 PF11842.8 AMK78703.1 - 3.8e-49 166.9 0.2 7e-49 166.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) Radical_SAM PF04055.21 AMK78703.1 - 3.7e-23 82.7 0.0 7.1e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Radical SAM superfamily B12-binding PF02310.19 AMK78703.1 - 0.0023 17.9 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 B12 binding domain Spermine_synth PF01564.17 AMK78704.1 - 1.5e-08 34.3 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 AMK78704.1 - 0.0045 17.6 0.0 0.008 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78704.1 - 0.062 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 AMK78704.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GST_N_3 PF13417.6 AMK78705.1 - 8.1e-09 35.8 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK78705.1 - 1.3e-08 35.1 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK78705.1 - 3e-08 33.8 0.0 6.8e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK78705.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AMK78705.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Amino_oxidase PF01593.24 AMK78707.1 - 6.5e-40 137.8 0.1 4.8e-24 85.5 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AMK78707.1 - 1.2e-14 54.3 0.0 3.4e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 AMK78707.1 - 6.6e-05 23.0 0.2 0.00025 21.1 0.2 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 AMK78707.1 - 0.0003 20.5 0.6 0.001 18.8 0.3 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 AMK78707.1 - 0.0094 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 AMK78707.1 - 0.011 14.4 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 AMK78707.1 - 0.034 14.7 0.1 0.059 13.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK78707.1 - 0.037 13.1 0.4 0.06 12.4 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 AMK78707.1 - 0.038 13.2 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 AMK78707.1 - 0.063 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 AMK78707.1 - 0.11 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Ist1 PF03398.14 AMK78709.1 - 0.0015 18.5 0.2 0.0027 17.6 0.2 1.5 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Seryl_tRNA_N PF02403.22 AMK78709.1 - 0.012 15.8 3.6 0.13 12.5 3.6 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 AMK78709.1 - 0.015 13.3 0.5 0.021 12.8 0.5 1.2 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 AMK78709.1 - 0.04 14.2 7.0 0.051 13.9 7.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SLATT_6 PF18169.1 AMK78709.1 - 0.046 13.3 0.2 0.061 12.9 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 JUPITER PF17054.5 AMK78709.1 - 0.05 13.1 2.3 0.062 12.8 2.3 1.0 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Pex19 PF04614.12 AMK78709.1 - 0.07 12.9 8.8 0.095 12.5 8.8 1.2 1 0 0 1 1 1 0 Pex19 protein family TipAS PF07739.13 AMK78709.1 - 0.14 12.7 10.3 22 5.6 8.6 2.9 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain CcmH PF03918.14 AMK78709.1 - 0.18 11.1 4.7 0.22 10.8 4.7 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein BshC PF10079.9 AMK78709.1 - 0.21 10.3 2.8 0.23 10.2 2.8 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC CSTF2_hinge PF14327.6 AMK78709.1 - 0.62 10.6 7.0 2.5 8.6 5.1 2.6 2 1 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 DUF3708 PF12501.8 AMK78709.1 - 0.62 9.8 3.4 0.89 9.3 3.3 1.4 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF4718 PF15842.5 AMK78709.1 - 0.75 9.6 3.3 0.92 9.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Chalcone_3 PF16036.5 AMK78709.1 - 0.89 9.6 5.0 0.69 10.0 2.6 1.7 1 1 1 2 2 2 0 Chalcone isomerase-like YlbD_coat PF14071.6 AMK78709.1 - 1.3 9.3 7.9 1.6 9.0 5.7 2.0 1 1 1 2 2 2 0 Putative coat protein DUF3138 PF11336.8 AMK78709.1 - 1.7 7.2 9.0 1.9 7.0 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Vps51 PF08700.11 AMK78710.1 - 0.023 14.8 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Vps51/Vps67 TIMELESS PF04821.14 AMK78711.1 - 0.027 13.8 0.6 0.029 13.7 0.6 1.2 1 0 0 1 1 1 0 Timeless protein DUF1257 PF06868.11 AMK78711.1 - 0.088 13.1 0.8 0.16 12.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1257) DUF2760 PF10816.8 AMK78712.1 - 4.8e-55 184.7 0.0 7.4e-55 184.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2760) LYRIC PF15686.5 AMK78712.1 - 0.26 10.8 0.3 0.35 10.4 0.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family HSP70 PF00012.20 AMK78713.1 - 1.3e-17 63.2 0.1 5.3e-16 57.9 0.0 2.4 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 AMK78713.1 - 2.5e-06 26.6 0.0 1.2e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein MutL PF13941.6 AMK78713.1 - 0.02 13.5 0.1 0.043 12.4 0.1 1.5 1 1 0 1 1 1 0 MutL protein Raco_middle PF17651.1 AMK78713.1 - 0.14 11.9 0.5 0.28 10.9 0.5 1.5 1 0 0 1 1 1 0 RACo middle region ROK PF00480.20 AMK78713.1 - 0.18 11.3 0.1 0.45 9.9 0.0 1.6 2 0 0 2 2 2 0 ROK family OmpA PF00691.20 AMK78714.1 - 2.3e-22 79.2 0.1 4.3e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 OmpA family Gly-zipper_YMGG PF13441.6 AMK78714.1 - 3.5e-07 29.9 20.7 6.4e-07 29.0 20.7 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 AMK78714.1 - 1e-06 28.6 21.8 2.1e-06 27.6 21.1 1.8 1 1 1 2 2 2 2 Glycine zipper Rick_17kDa_Anti PF05433.15 AMK78714.1 - 2.5e-06 27.3 21.2 4e-06 26.6 21.2 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF3482 PF11981.8 AMK78714.1 - 0.013 14.9 7.8 0.035 13.5 7.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_OmpA PF13436.6 AMK78714.1 - 0.019 14.8 25.6 0.043 13.6 25.6 1.6 1 1 0 1 1 1 0 Glycine-zipper domain TrbC PF04956.13 AMK78714.1 - 0.062 13.5 1.6 0.14 12.4 1.6 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family YtxH PF12732.7 AMK78714.1 - 0.12 12.9 11.0 0.33 11.5 0.0 2.7 2 0 0 2 2 2 0 YtxH-like protein DUF642 PF04862.12 AMK78718.1 - 0.0021 17.8 0.1 0.0029 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF642) PEP-CTERM PF07589.11 AMK78718.1 - 0.0054 16.8 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 PEP-CTERM motif CBM_4_9 PF02018.17 AMK78718.1 - 0.014 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain FA_hydroxylase PF04116.13 AMK78719.1 - 3.3e-25 89.0 10.4 3.3e-25 89.0 10.4 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NLE PF08154.12 AMK78720.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain PMEI PF04043.15 AMK78720.1 - 0.13 12.7 0.7 0.37 11.1 0.3 1.9 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PEP-CTERM PF07589.11 AMK78722.1 - 0.001 19.0 1.1 0.0029 17.6 1.1 1.8 1 0 0 1 1 1 1 PEP-CTERM motif VPDSG-CTERM PF18205.1 AMK78722.1 - 2.3 8.1 5.2 0.39 10.6 0.6 2.2 2 0 0 2 2 2 0 VPDSG-CTERM motif MOSC PF03473.17 AMK78723.1 - 1.6e-30 105.8 0.0 2.4e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 AMK78723.1 - 6.9e-27 93.7 0.0 1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain PilZ PF07238.14 AMK78724.1 - 1.1e-11 45.0 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 PilZ domain Peripla_BP_6 PF13458.6 AMK78725.1 - 2.6e-08 33.9 0.5 3e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein ANF_receptor PF01094.28 AMK78725.1 - 0.033 13.3 0.0 0.061 12.4 0.0 1.4 1 1 0 1 1 1 0 Receptor family ligand binding region UvrB_inter PF17757.1 AMK78726.1 - 1.7e-32 111.5 0.2 4.8e-32 110.0 0.2 1.9 1 0 0 1 1 1 1 UvrB interaction domain UvrB PF12344.8 AMK78726.1 - 5.4e-21 74.2 0.6 5.4e-21 74.2 0.6 2.2 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AMK78726.1 - 6.7e-18 65.0 0.1 2.1e-17 63.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UVR PF02151.19 AMK78726.1 - 1.6e-10 40.4 6.1 5.2e-10 38.7 6.1 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.15 AMK78726.1 - 3e-09 37.1 0.0 1.1e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AMK78726.1 - 0.00011 22.0 0.1 0.00039 20.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 AMK78726.1 - 0.0008 19.2 0.0 0.0089 15.8 0.0 2.8 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 AMK78726.1 - 0.019 15.1 0.0 0.065 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 AMK78726.1 - 0.026 13.5 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinesin motor domain AAA PF00004.29 AMK78726.1 - 0.045 14.2 0.2 1.6 9.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 AMK78726.1 - 0.048 13.8 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 AMK78726.1 - 0.07 13.5 0.5 12 6.3 0.0 3.1 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 AMK78726.1 - 0.15 12.6 0.0 26 5.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 AMK78726.1 - 0.23 11.7 3.2 0.34 11.2 0.0 3.0 5 1 0 5 5 5 0 AAA domain EAL PF00563.20 AMK78727.1 - 1.5e-76 257.0 0.0 3.5e-76 255.9 0.0 1.6 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 AMK78727.1 - 1.1e-30 106.5 0.1 2e-30 105.6 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HMGL-like PF00682.19 AMK78727.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 HMGL-like zf-dskA_traR PF01258.17 AMK78728.1 - 3.4e-12 46.1 6.9 4.7e-12 45.6 6.9 1.2 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger C1_1 PF00130.22 AMK78728.1 - 0.0012 18.7 1.7 0.0016 18.2 1.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 AMK78728.1 - 0.004 17.2 1.6 0.0044 17.0 1.6 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 AMK78728.1 - 0.0048 16.3 2.7 0.061 12.8 2.9 2.2 1 1 1 2 2 2 2 zinc-ribbon domain DZR PF12773.7 AMK78728.1 - 0.02 14.9 5.3 0.039 14.0 5.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 AMK78728.1 - 0.068 12.8 0.2 0.068 12.8 0.2 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 AMK78728.1 - 0.082 12.6 4.9 0.46 10.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 AMK78728.1 - 0.24 11.5 5.1 4 7.6 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 FemAB_like PF04339.12 AMK78729.1 - 1.1e-156 521.6 4.7 1.3e-156 521.4 4.7 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 AMK78729.1 - 2.3e-12 47.3 0.1 2.3e-12 47.3 0.1 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF938 PF06080.12 AMK78730.1 - 4.2e-64 216.1 0.0 4.9e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 AMK78730.1 - 0.0013 19.4 0.0 0.0025 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78730.1 - 0.0086 16.7 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 AMK78730.1 - 0.14 11.6 0.0 8.4 5.8 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain LemA PF04011.12 AMK78731.1 - 1.4e-58 197.0 0.8 1.6e-58 196.8 0.8 1.1 1 0 0 1 1 1 1 LemA family DUF1869 PF08956.10 AMK78731.1 - 0.09 12.7 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) FPP PF05911.11 AMK78731.1 - 0.16 10.2 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TPM_phosphatase PF04536.14 AMK78732.1 - 2.3e-39 134.4 0.2 2.9e-39 134.1 0.2 1.1 1 0 0 1 1 1 1 TPM domain MOLO1 PF17175.4 AMK78732.1 - 0.025 14.7 0.0 0.076 13.1 0.0 1.7 1 1 0 1 1 1 0 Modulator of levamisole receptor-1 Sugarporin_N PF11471.8 AMK78732.1 - 0.057 13.4 7.9 0.75 9.8 2.2 2.5 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Pilus_CpaD PF09476.10 AMK78732.1 - 0.26 11.0 2.0 0.43 10.3 2.0 1.4 1 1 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF4191 PF13829.6 AMK78732.1 - 6.1 6.1 6.4 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TPM_phosphatase PF04536.14 AMK78733.1 - 2.8e-15 56.6 0.0 3.3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 TPM domain DUF5130 PF17174.4 AMK78733.1 - 0.0066 16.7 0.0 0.009 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) HSP20 PF00011.21 AMK78734.1 - 1.4e-17 63.7 0.3 1.6e-17 63.5 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AMK78734.1 - 1.1e-06 28.1 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 AMK78734.1 - 0.11 13.6 0.0 0.2 12.7 0.0 1.5 1 1 0 1 1 1 0 CS domain FAD_binding_1 PF00667.20 AMK78735.1 - 2.1e-32 112.5 0.0 3.6e-31 108.5 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 AMK78735.1 - 8.2e-32 110.4 0.1 3.2e-31 108.5 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 AMK78735.1 - 6.1e-18 65.5 0.0 5e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glu_synthase PF01645.17 AMK78736.1 - 1.1e-101 340.6 10.2 3.5e-99 332.4 3.3 2.9 4 0 0 4 4 4 2 Conserved region in glutamate synthase GATase_2 PF00310.21 AMK78736.1 - 9.9e-92 307.8 0.0 1.5e-91 307.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 AMK78736.1 - 4.5e-73 246.1 0.4 2.2e-72 243.9 0.2 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 AMK78736.1 - 2.3e-49 167.6 7.5 4.7e-49 166.6 7.5 1.5 1 0 0 1 1 1 1 GXGXG motif FAD_binding_3 PF01494.19 AMK78737.1 - 4.7e-25 88.6 0.5 3.3e-22 79.2 0.0 2.3 3 0 0 3 3 3 2 FAD binding domain SE PF08491.10 AMK78737.1 - 4.1e-09 35.9 0.1 1.1e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 AMK78737.1 - 1.7e-06 27.2 1.5 0.00076 18.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 AMK78737.1 - 3.5e-06 26.3 0.7 0.34 9.9 0.3 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein Pyr_redox_2 PF07992.14 AMK78737.1 - 1.6e-05 24.3 0.3 0.059 12.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK78737.1 - 6e-05 22.8 0.1 8.5e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 AMK78737.1 - 0.0031 16.8 0.3 0.0067 15.7 0.3 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 AMK78737.1 - 0.031 14.9 1.3 0.27 11.8 2.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AMK78737.1 - 0.036 14.3 1.9 0.17 12.1 1.9 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 AMK78737.1 - 0.23 10.1 1.3 11 4.6 1.4 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 AMK78737.1 - 0.69 8.9 5.0 0.39 9.7 2.2 1.9 3 0 0 3 3 3 0 FAD binding domain GlnD_UR_UTase PF08335.11 AMK78738.1 - 2.3e-36 125.1 0.0 5.6e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase HD PF01966.22 AMK78738.1 - 2.7e-11 43.7 0.2 6.5e-11 42.5 0.2 1.6 1 0 0 1 1 1 1 HD domain NTP_transf_2 PF01909.23 AMK78738.1 - 9.9e-05 22.6 0.0 0.00041 20.6 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain ACT PF01842.25 AMK78738.1 - 0.00042 20.0 0.3 0.0026 17.5 0.1 2.4 2 0 0 2 2 2 1 ACT domain Peptidase_M24 PF00557.24 AMK78739.1 - 2.6e-53 180.8 0.3 2.9e-53 180.7 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S2 PF00318.20 AMK78740.1 - 4.2e-93 310.5 0.0 4.9e-93 310.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 Polysacc_deac_2 PF04748.13 AMK78740.1 - 0.081 12.1 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase PTCB-BRCT PF12738.7 AMK78740.1 - 0.23 11.4 0.5 3.6 7.6 0.1 2.4 2 0 0 2 2 2 0 twin BRCT domain EF_TS PF00889.19 AMK78741.1 - 1.3e-68 230.7 0.6 1.8e-68 230.2 0.6 1.2 1 0 0 1 1 1 1 Elongation factor TS SOR PF07682.11 AMK78741.1 - 0.0069 15.3 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Sulphur oxygenase reductase DUF5300 PF17224.3 AMK78741.1 - 0.015 15.6 1.1 0.18 12.1 1.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5300) AA_kinase PF00696.28 AMK78742.1 - 1.5e-28 100.1 0.4 1.8e-28 99.8 0.4 1.0 1 0 0 1 1 1 1 Amino acid kinase family Avl9 PF09794.9 AMK78742.1 - 0.19 10.4 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 RRF PF01765.19 AMK78743.1 - 8.3e-63 211.2 3.9 1.1e-62 210.7 3.9 1.2 1 0 0 1 1 1 1 Ribosome recycling factor 14-3-3 PF00244.20 AMK78743.1 - 0.0056 16.2 0.8 0.0082 15.7 0.8 1.4 1 0 0 1 1 1 1 14-3-3 protein Myb_DNA-bind_4 PF13837.6 AMK78743.1 - 0.12 12.8 1.7 0.37 11.2 1.7 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF883 PF05957.13 AMK78743.1 - 0.75 10.4 6.3 0.35 11.5 3.9 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Prenyltransf PF01255.19 AMK78744.1 - 1.2e-80 270.3 0.0 1.3e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CTP_transf_1 PF01148.20 AMK78745.1 - 1.5e-54 185.6 19.6 2.1e-54 185.1 19.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DXP_reductoisom PF02670.16 AMK78746.1 - 2.6e-45 154.3 2.6 5.1e-45 153.3 2.6 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 AMK78746.1 - 7e-45 152.0 0.5 1.4e-44 151.1 0.3 1.6 2 0 0 2 2 2 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AMK78746.1 - 1.9e-38 130.5 0.0 4.8e-38 129.2 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Semialdhyde_dh PF01118.24 AMK78746.1 - 0.033 14.6 0.3 0.26 11.7 0.0 2.5 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF2537 PF10801.8 AMK78746.1 - 0.056 13.7 2.2 4.1 7.7 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Peptidase_M50 PF02163.22 AMK78747.1 - 4.9e-77 258.6 0.3 5.7e-77 258.4 0.3 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AMK78747.1 - 1.1e-15 57.2 1.4 3.6e-07 29.9 0.2 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 AMK78747.1 - 5.2e-10 39.5 0.0 0.00015 22.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 AMK78747.1 - 2.4e-08 34.2 0.1 0.0019 18.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain HCO3_cotransp PF00955.21 AMK78747.1 - 0.0071 15.2 0.5 0.01 14.7 0.5 1.2 1 0 0 1 1 1 1 HCO3- transporter family Thioredoxin_2 PF13098.6 AMK78748.1 - 1.1e-28 99.9 0.0 1.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 AMK78748.1 - 7e-23 79.8 0.0 1.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus Thioredoxin_4 PF13462.6 AMK78748.1 - 9.5e-07 29.1 0.1 5.1e-05 23.5 0.2 2.3 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 AMK78748.1 - 1e-06 28.7 0.2 0.0031 17.3 0.0 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin PF00085.20 AMK78748.1 - 0.093 12.7 0.1 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin OmpA PF00691.20 AMK78749.1 - 2.5e-14 53.4 0.0 1.7e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 OmpA family FecR PF04773.13 AMK78750.1 - 5.5e-12 46.1 0.0 8.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 FecR protein CHASE2 PF05226.11 AMK78751.1 - 5.2e-46 157.4 0.7 1.3e-45 156.2 0.7 1.6 1 0 0 1 1 1 1 CHASE2 domain HATPase_c PF02518.26 AMK78751.1 - 1.6e-23 83.4 0.1 3.3e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78751.1 - 5.9e-17 61.5 0.4 1.4e-16 60.3 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AMK78751.1 - 4.8e-05 23.6 0.0 0.00015 22.0 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AMK78751.1 - 0.0023 17.9 0.0 0.005 16.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK78751.1 - 0.0044 17.3 0.0 0.018 15.3 0.0 2.0 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 AMK78751.1 - 0.02 14.9 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 PAS domain MutS_V PF00488.21 AMK78752.1 - 2.5e-87 291.8 0.1 4.1e-87 291.1 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AMK78752.1 - 8.8e-44 148.3 0.0 1.9e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 AMK78752.1 - 6.3e-39 134.2 1.7 1.3e-38 133.1 1.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 AMK78752.1 - 1.4e-30 105.5 0.2 3.6e-30 104.2 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 AMK78752.1 - 1.8e-24 86.6 0.0 3.5e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 AMK78752.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DMAP1_like PF17024.5 AMK78754.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative DMAP1-like rve PF00665.26 AMK78755.1 - 2.8e-30 104.9 1.0 8.3e-29 100.2 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 AMK78755.1 - 4.5e-12 45.6 0.1 9.9e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK78755.1 - 1.1e-11 44.7 1.1 2e-11 43.8 1.1 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AMK78755.1 - 3.8e-10 39.7 0.7 1.1e-09 38.3 0.7 1.7 1 0 0 1 1 1 1 HTH-like domain DDE_Tnp_IS240 PF13610.6 AMK78755.1 - 1.1e-09 38.7 0.3 1.6e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 DDE domain HTH_Tnp_1 PF01527.20 AMK78755.1 - 0.0057 17.0 0.1 0.026 14.8 0.1 2.2 2 0 0 2 2 2 1 Transposase PDDEXK_5 PF11645.8 AMK78756.1 - 3.7e-08 33.4 0.0 4.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK endonuclease Methyltransf_31 PF13847.6 AMK78757.1 - 5.4e-22 78.2 0.0 7.2e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK78757.1 - 5.6e-22 78.2 0.0 1.5e-21 76.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78757.1 - 2.1e-21 76.4 0.0 1.3e-20 73.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK78757.1 - 1.2e-15 58.1 0.0 2.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK78757.1 - 2.8e-13 50.0 0.0 4.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK78757.1 - 2.4e-10 40.1 0.0 5.8e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AMK78757.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 AMK78757.1 - 2.6e-08 33.6 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 AMK78757.1 - 2e-06 27.0 0.0 2.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 AMK78757.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 AMK78757.1 - 1.2e-05 24.8 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 AMK78757.1 - 0.00021 20.8 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 AMK78757.1 - 0.0021 17.5 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 AMK78757.1 - 0.0024 17.0 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_2 PF00891.18 AMK78757.1 - 0.0033 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 AMK78757.1 - 0.0047 16.4 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.20 AMK78757.1 - 0.0052 15.9 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 AMK78757.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 AMK78757.1 - 0.045 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 AMK78757.1 - 0.083 12.4 0.1 0.25 10.8 0.1 1.8 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 AMK78757.1 - 0.087 12.5 0.2 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F ATPgrasp_Ter PF15632.6 AMK78757.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon HMGL-like PF00682.19 AMK78758.1 - 1.7e-77 260.5 0.3 3e-77 259.8 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 AMK78758.1 - 7.7e-25 87.3 0.0 1.5e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AsnC_trans_reg PF01037.21 AMK78759.1 - 1.3e-21 76.4 0.0 1.8e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 AMK78759.1 - 2.3e-20 71.9 0.7 3.7e-20 71.2 0.2 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 AMK78759.1 - 4.7e-19 67.9 2.5 1.6e-18 66.2 0.7 2.3 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 AMK78759.1 - 1.8e-07 31.1 0.0 0.00026 21.0 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 AMK78759.1 - 1.6e-05 24.7 0.2 0.00019 21.3 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 AMK78759.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 AMK78759.1 - 0.00016 21.5 0.0 0.00038 20.3 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 AMK78759.1 - 0.00028 20.8 0.1 0.00061 19.7 0.0 1.6 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.10 AMK78759.1 - 0.00035 20.3 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_47 PF16221.5 AMK78759.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix HTH_10 PF04967.12 AMK78759.1 - 0.045 13.6 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain HTH_CodY PF08222.11 AMK78759.1 - 0.056 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_27 PF13463.6 AMK78759.1 - 0.13 12.7 0.0 0.34 11.4 0.0 1.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain Crp PF00325.20 AMK78759.1 - 0.14 11.8 0.3 0.96 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Beta-lactamase PF00144.24 AMK78760.1 - 1.4e-64 218.5 0.1 1.9e-64 218.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase TfoX_N PF04993.13 AMK78761.1 - 1e-32 112.2 1.4 1.3e-32 111.9 1.4 1.1 1 0 0 1 1 1 1 TfoX N-terminal domain DUF1697 PF08002.11 AMK78762.1 - 1.3e-37 129.2 0.0 2e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) F-box PF00646.33 AMK78762.1 - 0.16 11.9 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 F-box domain DUF3285 PF11688.8 AMK78763.1 - 0.1 12.5 0.6 0.1 12.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) HTH_18 PF12833.7 AMK78764.1 - 1.2e-15 57.6 1.4 2.4e-15 56.6 1.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 AMK78764.1 - 1.6e-07 31.2 0.4 0.01 15.9 0.2 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DHBP_synthase PF00926.19 AMK78765.1 - 1.1e-77 259.9 0.2 1.3e-77 259.7 0.2 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase EamA PF00892.20 AMK78767.1 - 4.3e-33 114.4 39.2 2.9e-17 63.1 12.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family Autoind_bind PF03472.15 AMK78768.1 - 1.3e-36 125.3 0.2 1.7e-36 124.9 0.2 1.2 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 AMK78768.1 - 1.6e-19 69.2 0.8 2.7e-19 68.5 0.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AMK78768.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 AMK78768.1 - 0.0049 16.9 0.1 0.14 12.3 0.0 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AMK78768.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 AMK78768.1 - 0.054 14.0 0.1 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 AMK78768.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK78768.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 AMK78768.1 - 0.11 12.3 0.1 0.37 10.6 0.1 1.9 1 0 0 1 1 1 0 HTH DNA binding domain Transglut_core PF01841.19 AMK78769.1 - 2.2e-15 57.1 0.0 2.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily CYTH PF01928.21 AMK78770.1 - 3.7e-14 53.1 0.0 4.2e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 CYTH domain DUF4442 PF14539.6 AMK78771.1 - 1.7e-13 50.8 0.0 2e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT PF03061.22 AMK78771.1 - 5.5e-06 26.7 0.3 0.0002 21.7 0.3 2.1 1 1 0 1 1 1 1 Thioesterase superfamily YiiD_C PF09500.10 AMK78771.1 - 6.8e-05 22.7 0.0 8.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) Cupin_2 PF07883.11 AMK78772.1 - 1.3e-17 63.3 0.1 2.8e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 AMK78772.1 - 5.3e-06 26.4 0.0 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain AraC_binding_2 PF14525.6 AMK78772.1 - 0.00018 21.3 0.0 0.00021 21.0 0.0 1.1 1 0 0 1 1 1 1 AraC-binding-like domain Cupin_1 PF00190.22 AMK78772.1 - 0.00024 20.7 0.0 0.00039 20.1 0.0 1.3 1 1 0 1 1 1 1 Cupin Cupin_3 PF05899.12 AMK78772.1 - 0.0099 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 AMK78772.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Lyx_isomer PF07385.12 AMK78772.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 D-lyxose isomerase His_Phos_1 PF00300.22 AMK78773.1 - 2.7e-07 30.5 0.0 8.8e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Shikimate_dh_N PF08501.11 AMK78774.1 - 1.5e-17 63.6 0.0 2.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 AMK78774.1 - 3.4e-08 33.6 0.0 6.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 AMK78774.1 - 0.0013 18.1 2.0 0.031 13.6 2.2 2.1 2 0 0 2 2 2 1 ThiF family F420_oxidored PF03807.17 AMK78774.1 - 0.041 14.5 0.1 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GARS_N PF02844.15 AMK78774.1 - 0.13 13.0 0.6 0.82 10.5 0.3 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Staph_opine_DH PF10100.9 AMK78774.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase DUF4260 PF14079.6 AMK78775.1 - 1.3e-41 141.1 0.6 1.5e-41 140.9 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Methyltransf_11 PF08241.12 AMK78776.1 - 0.0014 19.3 0.1 0.11 13.1 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 AMK78776.1 - 0.0054 17.4 0.1 0.62 10.8 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Acetyltransf_7 PF13508.7 AMK78777.1 - 1.5e-06 28.5 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK78777.1 - 3.2e-06 27.4 0.0 4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 AMK78777.1 - 0.0028 17.8 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 AMK78777.1 - 0.0042 17.0 0.0 0.0067 16.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AMK78777.1 - 0.056 13.4 0.1 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein PanZ PF12568.8 AMK78777.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ BSP PF04450.12 AMK78778.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria HAD_2 PF13419.6 AMK78779.1 - 3e-21 76.3 0.0 4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AMK78779.1 - 2.6e-13 50.8 0.0 3.6e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK78779.1 - 1.5e-07 32.0 0.0 1.9e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AMK78779.1 - 2.5e-05 24.3 0.0 4.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 AMK78779.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GFA PF04828.14 AMK78780.1 - 1.4e-21 76.6 0.2 1.7e-21 76.3 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 AMK78780.1 - 0.0037 17.4 1.2 0.028 14.6 0.0 2.1 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 AMK78780.1 - 0.028 14.1 0.1 0.028 14.1 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RNA_POL_M_15KD PF02150.16 AMK78780.1 - 0.28 11.1 5.1 0.72 9.8 0.3 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 AMK78780.1 - 0.41 10.6 5.9 0.47 10.4 0.2 2.9 3 0 0 3 3 3 0 Nudix N-terminal Peptidase_A8 PF01252.18 AMK78781.1 - 1.6e-26 93.2 1.0 2.1e-26 92.9 1.0 1.1 1 0 0 1 1 1 1 Signal peptidase (SPase) II Elf1 PF05129.13 AMK78781.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Amidase PF01425.21 AMK78782.1 - 7e-80 269.2 0.2 9.5e-79 265.4 0.2 2.0 1 1 0 1 1 1 1 Amidase LIDHydrolase PF10230.9 AMK78783.1 - 6e-09 35.8 0.0 7.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 AMK78783.1 - 2.3e-07 30.7 0.3 5.6e-07 29.5 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK78783.1 - 6.4e-07 30.2 0.6 7.9e-07 29.9 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AMK78783.1 - 8.9e-07 28.4 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 AMK78783.1 - 6.3e-05 22.9 0.0 0.00084 19.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 AMK78783.1 - 0.0001 22.5 0.1 0.00025 21.2 0.1 1.7 1 1 0 1 1 1 1 Thioesterase domain DUF726 PF05277.12 AMK78783.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Palm_thioest PF02089.15 AMK78783.1 - 0.075 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase GATase PF00117.28 AMK78784.1 - 5.3e-17 62.2 0.0 7.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AMK78784.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 AMK78784.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF1330 PF07045.11 AMK78785.1 - 5.6e-28 97.1 0.0 6.2e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Tautomerase_2 PF14552.6 AMK78786.1 - 3.7e-23 81.4 0.1 5.7e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase PF01361.21 AMK78786.1 - 9.4e-10 38.3 0.0 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_3 PF14832.6 AMK78786.1 - 0.013 15.7 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme CHMI PF02962.15 AMK78786.1 - 0.015 15.7 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 5-carboxymethyl-2-hydroxymuconate isomerase FMN_bind_2 PF04299.12 AMK78787.1 - 4e-60 202.3 0.0 5.4e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain Acetyltransf_1 PF00583.25 AMK78788.1 - 1e-13 51.6 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AMK78788.1 - 2.2e-10 40.6 0.0 3.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AMK78788.1 - 2.2e-08 34.4 0.0 3.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AMK78788.1 - 2.5e-05 25.0 0.0 3.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AMK78788.1 - 5.1e-05 23.5 0.0 6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK78788.1 - 9.9e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AMK78788.1 - 0.0071 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AMK78788.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 AMK78788.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_8 PF13523.6 AMK78788.1 - 0.016 14.9 0.0 0.048 13.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP2 PF01569.21 AMK78789.1 - 5e-10 39.3 0.8 5e-10 39.3 0.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AMK78789.1 - 0.091 12.4 6.5 0.21 11.3 6.5 1.7 1 1 0 1 1 1 0 PAP2 superfamily Abhydrolase_6 PF12697.7 AMK78790.1 - 1.7e-15 58.2 4.6 2.3e-15 57.8 4.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AMK78790.1 - 2.4e-13 50.3 0.7 1e-12 48.2 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AMK78790.1 - 2.5e-08 33.5 0.1 3.9e-08 32.9 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 AMK78790.1 - 0.04 14.0 0.0 0.89 9.6 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 AMK78790.1 - 0.065 12.9 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1057 PF06342.12 AMK78790.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) GST_N_2 PF13409.6 AMK78791.1 - 3.3e-11 43.3 0.0 6.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 AMK78791.1 - 9.5e-11 42.0 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK78791.1 - 6.2e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK78791.1 - 3e-05 24.0 3.5 3.7e-05 23.7 2.2 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AMK78791.1 - 0.0082 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 AMK78791.1 - 0.021 15.2 0.1 0.078 13.3 0.0 1.9 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 AMK78791.1 - 0.022 15.5 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 AMK78791.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GFA PF04828.14 AMK78792.1 - 4e-09 36.7 0.6 4e-09 36.7 0.6 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Flavodoxin_5 PF12724.7 AMK78793.1 - 3.4e-41 140.9 0.0 4e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 AMK78793.1 - 0.022 14.4 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain GST_N_3 PF13417.6 AMK78794.1 - 5.4e-15 55.6 0.0 9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AMK78794.1 - 2.3e-13 50.3 0.0 3.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AMK78794.1 - 8.1e-10 38.9 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 AMK78794.1 - 5.5e-07 29.5 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 AMK78794.1 - 1e-06 28.8 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABM PF03992.16 AMK78795.1 - 1.2e-10 41.3 0.1 1.5e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SOR PF07682.11 AMK78795.1 - 0.088 11.7 0.1 0.19 10.6 0.1 1.7 1 1 0 1 1 1 0 Sulphur oxygenase reductase TetR_N PF00440.23 AMK78797.1 - 7.3e-11 41.7 0.1 1.3e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AMK78797.1 - 0.013 15.8 0.7 0.024 14.9 0.3 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 AMK78797.1 - 0.018 15.8 1.3 0.11 13.2 0.5 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_2 PF00891.18 AMK78798.1 - 1e-34 119.7 0.2 1.4e-34 119.3 0.2 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 AMK78798.1 - 7.9e-10 38.6 0.0 2.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.6 AMK78798.1 - 0.015 16.0 0.1 0.3 11.8 0.1 2.5 1 1 1 2 2 2 0 Methyltransferase domain HTH_47 PF16221.5 AMK78798.1 - 0.023 14.2 0.4 0.043 13.4 0.4 1.4 1 0 0 1 1 1 0 winged helix-turn-helix HTH_20 PF12840.7 AMK78798.1 - 0.04 14.0 0.8 0.12 12.5 0.8 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 AMK78798.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4400 PF14348.6 AMK78799.1 - 6.7e-23 81.3 1.2 8e-23 81.0 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) TrwB_AAD_bind PF10412.9 AMK78800.1 - 2.3e-15 56.4 0.0 6.9e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 AMK78800.1 - 1e-12 48.2 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG AAA_10 PF12846.7 AMK78800.1 - 7.2e-09 35.0 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 AMK78800.1 - 2.6e-05 24.4 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain T4SS-DNA_transf PF02534.14 AMK78800.1 - 3.5e-05 22.8 0.0 0.0014 17.5 0.0 2.1 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer DUF853 PF05872.12 AMK78800.1 - 0.00021 20.0 0.0 0.00035 19.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 AMK78800.1 - 0.00029 20.3 0.1 0.0064 15.9 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AMK78800.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 AMK78800.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase TraI_2 PF07514.11 AMK78801.1 - 4.1e-97 325.1 0.7 5.5e-97 324.6 0.7 1.2 1 0 0 1 1 1 1 Putative helicase HD_6 PF18019.1 AMK78801.1 - 0.014 15.6 0.4 0.033 14.3 0.4 1.7 1 0 0 1 1 1 0 HD domain HD PF01966.22 AMK78801.1 - 0.019 15.2 0.1 0.083 13.1 0.1 1.9 1 1 0 1 1 1 0 HD domain DUF4489 PF14879.6 AMK78801.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) GxGYxYP_N PF16216.5 AMK78802.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Fip1 PF05182.13 AMK78802.1 - 0.22 11.0 1.1 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Fip1 motif TrfA PF07042.11 AMK78803.1 - 7.3e-16 58.0 0.0 9.1e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 TrfA protein RPA PF10134.9 AMK78803.1 - 0.00022 20.8 0.1 0.00079 19.0 0.0 2.0 3 1 0 3 3 3 1 Replication initiator protein A rve PF00665.26 AMK78804.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_5 PF01022.20 AMK78804.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AMK78804.1 - 0.00036 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AMK78804.1 - 0.0018 18.0 1.3 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AMK78804.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.12 AMK78804.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AMK78804.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK78804.1 - 0.037 13.8 0.1 0.89 9.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 AMK78804.1 - 0.038 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK78804.1 - 0.044 13.8 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 AMK78804.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 AMK78804.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 AMK78804.1 - 0.12 12.5 0.0 0.81 9.9 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AMK78804.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain IstB_IS21 PF01695.17 AMK78805.1 - 6.5e-55 185.6 0.0 8.4e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK78805.1 - 3.1e-08 33.7 0.0 4.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK78805.1 - 0.00012 21.6 0.1 0.00018 21.1 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein Phage_int_SAM_4 PF13495.6 AMK78806.1 - 0.21 12.1 0.0 35 4.9 0.0 2.4 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain PG_binding_1 PF01471.18 AMK78807.1 - 1.4e-13 50.8 0.0 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain SLT PF01464.20 AMK78807.1 - 1.5e-12 47.2 0.0 2.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_3 PF09374.10 AMK78807.1 - 0.066 13.5 0.0 7.6 6.9 0.1 2.4 1 1 1 2 2 2 0 Predicted Peptidoglycan domain DUF2937 PF11157.8 AMK78808.1 - 2.9 7.6 6.7 0.26 11.0 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) FliT PF05400.13 AMK78808.1 - 6.6 7.6 10.8 14 6.5 0.2 3.4 3 1 0 3 3 3 0 Flagellar protein FliT DUF4834 PF16118.5 AMK78809.1 - 0.14 13.1 0.4 1.5 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) GTA_holin_3TM PF11351.8 AMK78809.1 - 6.4 7.3 5.7 1.3 9.6 0.1 2.6 3 0 0 3 3 3 0 Holin of 3TMs, for gene-transfer release Peptidase_M41 PF01434.18 AMK78811.1 - 3.7e-64 216.1 0.1 5.8e-64 215.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AMK78811.1 - 9.9e-43 145.7 0.0 2.1e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AMK78811.1 - 4.2e-17 61.7 1.4 9.3e-16 57.4 0.1 2.5 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 AMK78811.1 - 1.7e-11 44.4 0.2 4.5e-11 43.1 0.2 1.8 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 AMK78811.1 - 1e-05 25.0 0.1 2.1e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 AMK78811.1 - 0.00011 22.2 0.0 0.00048 20.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AMK78811.1 - 0.0015 18.3 0.0 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AMK78811.1 - 0.0037 17.7 5.4 0.042 14.2 0.4 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 AMK78811.1 - 0.005 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Peptidase_M50B PF13398.6 AMK78811.1 - 0.0058 16.3 0.2 0.99 9.0 0.0 2.3 2 0 0 2 2 2 1 Peptidase M50B-like ATPase PF06745.13 AMK78811.1 - 0.0058 16.0 0.9 0.52 9.6 0.1 2.4 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 AMK78811.1 - 0.016 15.0 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 AMK78811.1 - 0.016 15.5 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 AMK78811.1 - 0.018 14.2 0.0 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 AMK78811.1 - 0.019 14.3 0.1 0.042 13.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.14 AMK78811.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 AMK78811.1 - 0.037 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 AMK78811.1 - 0.039 13.3 0.1 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 AMK78811.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 AMK78811.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 AMK78811.1 - 0.13 11.8 0.1 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AMK78811.1 - 0.14 11.7 0.1 0.48 9.9 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoD PF09423.10 AMK78812.1 - 1.9e-29 102.8 0.0 2.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase HTH_Tnp_1 PF01527.20 AMK78813.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK78813.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK78813.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78813.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK78813.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK78813.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK78814.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK78814.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK78814.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK78814.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK78814.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK78814.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK78814.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 rve PF00665.26 AMK78816.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK78816.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK78816.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK78816.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK78816.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK78816.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK78816.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 HTH_Tnp_1 PF01527.20 AMK78817.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK78817.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK78817.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78817.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK78817.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK78817.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pep_M12B_propep PF01562.19 AMK78818.1 - 0.0032 17.7 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_C1 PF00112.23 AMK78819.1 - 4.2e-14 53.2 0.0 5.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 AMK78819.1 - 0.019 13.8 0.3 0.029 13.2 0.3 1.2 1 0 0 1 1 1 0 Peptidase C1-like family HATPase_c PF02518.26 AMK78820.1 - 5.6e-15 55.8 0.0 9.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AMK78820.1 - 2.7e-08 33.9 0.1 6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AMK78820.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AC_N PF16214.5 AMK78820.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region NDUF_B12 PF08122.12 AMK78820.1 - 0.075 13.1 0.7 11 6.2 0.0 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family HATPase_c_5 PF14501.6 AMK78820.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 GHKL domain ABC2_membrane_3 PF12698.7 AMK78821.1 - 6.2e-08 32.1 9.2 6.2e-08 32.1 9.2 2.7 2 2 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 AMK78822.1 - 4.3e-29 101.8 0.0 6.4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK78822.1 - 7.2e-17 62.1 0.6 5.8e-09 36.2 0.3 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK78822.1 - 4.1e-06 27.4 0.0 7.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AMK78822.1 - 1.5e-05 24.6 0.0 0.064 12.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AMK78822.1 - 1.5e-05 25.4 0.3 3.5e-05 24.2 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AMK78822.1 - 4.5e-05 23.7 0.0 0.00014 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AMK78822.1 - 0.00034 20.3 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AMK78822.1 - 0.0006 19.6 0.0 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 AMK78822.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AMK78822.1 - 0.022 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AMK78822.1 - 0.024 14.8 0.1 0.11 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AMK78822.1 - 0.034 13.9 0.2 0.094 12.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AMK78822.1 - 0.037 14.5 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 AMK78822.1 - 0.042 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 AMK78822.1 - 0.047 13.3 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 AMK78822.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AMK78822.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 AMK78822.1 - 0.21 11.2 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 AMK78822.1 - 0.26 9.9 0.0 0.86 8.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Iso_dh PF00180.20 AMK78823.1 - 5.2e-107 358.0 0.9 5.9e-107 357.8 0.9 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Uma2 PF05685.12 AMK78824.1 - 3.2e-30 104.9 0.1 3.9e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Putative restriction endonuclease polyprenyl_synt PF00348.17 AMK78824.1 - 0.0074 15.4 0.1 0.015 14.3 0.1 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase Aconitase_2_N PF06434.13 AMK78825.1 - 5e-98 326.7 0.0 8.4e-98 326.0 0.0 1.4 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 AMK78825.1 - 5.7e-67 224.6 0.4 9e-67 223.9 0.4 1.3 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 AMK78825.1 - 1.9e-40 139.3 0.0 1.2e-38 133.4 0.0 2.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) GGDEF PF00990.21 AMK78826.1 - 1.3e-48 164.8 0.0 1.9e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DUF484 PF04340.12 AMK78826.1 - 3e-08 33.6 0.1 1e-07 31.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF484 GAF_3 PF13492.6 AMK78826.1 - 4.9e-05 23.7 0.0 0.042 14.2 0.0 2.4 2 0 0 2 2 2 2 GAF domain GGDEF_2 PF17853.1 AMK78826.1 - 0.00024 21.3 0.1 0.0005 20.3 0.1 1.5 1 1 0 1 1 1 1 GGDEF-like domain GAF_2 PF13185.6 AMK78826.1 - 0.00076 19.8 0.0 0.0028 17.9 0.0 1.9 1 1 0 1 1 1 1 GAF domain GDP_Man_Dehyd PF16363.5 AMK78827.1 - 1.8e-62 211.7 0.0 2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 AMK78827.1 - 1.2e-52 178.8 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AMK78827.1 - 6.9e-21 74.5 0.0 1.8e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 AMK78827.1 - 2e-19 69.9 0.0 1.3e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 AMK78827.1 - 2.3e-12 46.6 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 AMK78827.1 - 9.5e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 AMK78827.1 - 3.2e-08 33.7 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AMK78827.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 AMK78827.1 - 2.3e-05 23.7 0.0 0.0037 16.5 0.0 2.7 1 1 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 AMK78827.1 - 0.00048 20.4 0.0 0.0016 18.7 0.1 1.8 1 1 1 2 2 2 1 TrkA-N domain adh_short_C2 PF13561.6 AMK78827.1 - 0.0042 16.7 0.0 0.0064 16.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 AMK78827.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 AMK78827.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family ATP_bind_3 PF01171.20 AMK78828.1 - 5.1e-15 55.7 0.0 7.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Gal_GalNac_35kD PF17337.2 AMK78828.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Galactose-inhibitable lectin 35 kDa subunit ketoacyl-synt PF00109.26 AMK78829.1 - 2.2e-42 145.4 1.1 2.2e-42 145.4 1.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AMK78829.1 - 1.7e-30 105.5 0.9 1.5e-29 102.4 0.5 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AMK78829.1 - 0.00013 21.4 1.0 0.00098 18.6 0.4 2.2 1 1 1 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AMK78829.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension FabA PF07977.13 AMK78830.1 - 2.8e-53 179.3 0.0 3.3e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain SLT PF01464.20 AMK78831.1 - 1.1e-28 99.2 0.1 2.8e-28 97.9 0.1 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_L PF14718.6 AMK78831.1 - 3.3e-16 59.2 1.9 3.3e-16 59.2 1.9 4.2 4 1 1 5 5 5 1 Soluble lytic murein transglycosylase L domain Cucumo_coat PF00760.18 AMK78831.1 - 0.0015 18.2 0.0 0.0051 16.5 0.0 1.9 1 0 0 1 1 1 1 Cucumovirus coat protein SLT_2 PF13406.6 AMK78831.1 - 0.0031 16.8 0.7 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Transglycosylase SLT domain TPR_6 PF13174.6 AMK78831.1 - 0.3 11.8 2.0 4.8 8.0 0.5 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 AMK78831.1 - 0.67 10.4 10.1 0.3 11.5 5.6 2.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain ABC_tran PF00005.27 AMK78832.1 - 1.9e-30 106.1 0.0 3.5e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AMK78832.1 - 8.6e-30 104.3 10.9 1.1e-29 104.0 10.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 AMK78832.1 - 1.8e-05 24.3 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 AMK78832.1 - 0.0007 18.9 8.9 0.0007 18.9 8.9 2.7 2 1 0 2 2 2 1 ABC transporter transmembrane region AAA_25 PF13481.6 AMK78832.1 - 0.0018 17.9 0.2 0.033 13.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK78832.1 - 0.0094 16.4 0.4 0.031 14.6 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 AMK78832.1 - 0.023 14.4 1.3 2.9 7.6 0.2 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 AMK78832.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AMK78832.1 - 0.069 12.5 0.4 0.23 10.8 0.2 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 AMK78832.1 - 0.083 13.2 2.6 0.29 11.4 0.6 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AMK78832.1 - 0.088 12.6 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 AMK78832.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 AMK78832.1 - 0.13 12.6 2.6 0.4 11.0 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PHP PF02811.19 AMK78833.1 - 5.6e-11 43.0 0.1 7.7e-11 42.6 0.1 1.3 1 1 0 1 1 1 1 PHP domain EAL PF00563.20 AMK78834.1 - 2.8e-67 226.7 0.0 5.1e-67 225.9 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK78834.1 - 6.6e-53 178.7 0.0 1.2e-52 177.9 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AMK78834.1 - 7.9e-37 125.4 0.6 3e-20 72.3 0.1 3.5 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 AMK78834.1 - 3.6e-26 91.5 0.1 1e-25 90.1 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 AMK78834.1 - 4.2e-25 88.0 0.0 1.5e-12 47.7 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 AMK78834.1 - 1.8e-18 66.8 0.8 1.2e-06 28.7 0.0 4.6 5 0 0 5 5 5 3 PAS fold PAS PF00989.25 AMK78834.1 - 8.9e-17 61.1 0.0 1.2e-09 38.2 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 AMK78834.1 - 1.3e-07 31.5 0.6 1.4e-05 25.0 0.0 4.0 4 1 0 4 4 4 1 PAS domain PAS_7 PF12860.7 AMK78834.1 - 0.0001 22.5 0.1 2.8 8.1 0.0 4.6 4 1 0 4 4 4 1 PAS fold PAS_12 PF18095.1 AMK78834.1 - 0.021 14.4 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain EMP24_GP25L PF01105.24 AMK78834.1 - 0.16 11.9 1.5 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD EAL PF00563.20 AMK78835.1 - 2.4e-68 230.2 0.2 4.7e-68 229.2 0.2 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK78835.1 - 3.4e-34 117.9 0.0 1.7e-33 115.7 0.0 2.2 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 AMK78835.1 - 1.5e-25 89.5 0.0 5e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 AMK78835.1 - 5.9e-11 42.5 0.0 2e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 PAS fold Response_reg PF00072.24 AMK78836.1 - 1.5e-45 153.9 1.0 8.7e-26 90.3 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 AMK78836.1 - 1.6e-31 109.1 0.0 3.4e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK78836.1 - 3e-20 72.0 0.5 1.9e-19 69.5 0.0 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE8 PF17152.4 AMK78836.1 - 4.3e-14 52.6 0.0 1.5e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Periplasmic sensor domain Hpt PF01627.23 AMK78836.1 - 9.2e-12 45.1 5.6 9.2e-12 45.1 5.6 2.5 2 0 0 2 2 2 1 Hpt domain HAMP PF00672.25 AMK78836.1 - 2.6e-09 37.3 0.1 7.9e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 AMK78836.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMP_2 PF10144.9 AMK78836.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.6 2 1 1 3 3 3 0 Bacterial virulence factor haemolysin DUF3974 PF13120.6 AMK78836.1 - 0.09 12.9 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Exonuc_VII_L PF02601.15 AMK78836.1 - 1.9 8.0 7.6 3.3 7.2 2.8 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Nup54 PF13874.6 AMK78836.1 - 5.1 7.2 9.1 0.37 10.9 0.6 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4154 PF13689.6 AMK78837.1 - 2.5e-38 131.5 0.0 2.8e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 YfiR/HmsC-like TonB_dep_Rec PF00593.24 AMK78838.1 - 6.3e-27 95.6 23.1 1.1e-26 94.8 23.1 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK78838.1 - 1.2e-22 80.5 0.0 3.3e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK78838.1 - 9e-05 21.6 2.1 0.0005 19.2 2.0 2.2 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family TonB_dep_Rec PF00593.24 AMK78839.1 - 2.7e-33 116.6 30.6 3.1e-33 116.4 29.4 1.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK78839.1 - 2.1e-17 63.6 0.6 4.4e-17 62.6 0.2 1.8 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain BrnT_toxin PF04365.13 AMK78841.1 - 1.4e-21 76.6 0.2 1.6e-21 76.4 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system CopG_antitoxin PF12441.8 AMK78842.1 - 1.7e-35 121.4 0.4 1.9e-35 121.3 0.4 1.0 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system DUF2169 PF09937.9 AMK78842.1 - 0.084 12.3 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) HTH_Tnp_1 PF01527.20 AMK78843.1 - 5e-08 33.2 0.3 5.8e-08 32.9 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 AMK78843.1 - 1.7e-07 31.2 0.1 2.2e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 AMK78843.1 - 2.1e-05 24.2 0.2 2.7e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_31 PF13560.6 AMK78843.1 - 9e-05 22.7 0.2 0.00011 22.5 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AMK78843.1 - 0.0021 18.2 0.1 0.0027 17.8 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.16 AMK78843.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_1_2 PF13022.6 AMK78843.1 - 0.018 15.2 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_1 PF00126.27 AMK78843.1 - 0.026 14.5 0.3 0.034 14.1 0.3 1.2 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Phage_CI_repr PF07022.13 AMK78843.1 - 0.033 14.3 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_37 PF13744.6 AMK78843.1 - 0.035 14.1 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF134 PF02001.16 AMK78843.1 - 0.055 14.0 0.0 0.057 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_7 PF02796.15 AMK78843.1 - 0.058 13.5 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_50 PF18024.1 AMK78843.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AMK78843.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_19 PF12844.7 AMK78843.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TruB_N PF01509.18 AMK78844.1 - 0.074 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) N_methyl PF07963.12 AMK78845.1 - 1.3e-07 30.8 1.5 1.3e-07 30.8 1.5 1.7 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif DUF1859 PF08948.10 AMK78845.1 - 0.12 12.3 0.1 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1859) N_methyl PF07963.12 AMK78846.1 - 2.8e-06 26.6 1.4 5e-06 25.8 1.4 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 AMK78847.1 - 5.6e-07 28.8 1.5 9.1e-07 28.2 1.5 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 AMK78848.1 - 8.2e-10 37.8 1.1 1.8e-09 36.7 1.1 1.7 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif zf-B_box PF00643.24 AMK78849.1 - 0.036 14.2 1.2 0.11 12.7 0.2 1.9 2 0 0 2 2 2 0 B-box zinc finger Laminin_G_3 PF13385.6 AMK78850.1 - 7e-19 68.5 5.7 7e-19 68.5 5.7 3.3 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.16 AMK78850.1 - 0.00014 21.4 0.1 0.00027 20.5 0.1 1.4 1 0 0 1 1 1 1 Sialidase, N-terminal domain T2SSF PF00482.23 AMK78851.1 - 9.7e-54 180.6 6.0 8.7e-27 93.6 0.4 2.2 2 0 0 2 2 2 2 Type II secretion system (T2SS), protein F Glucos_trans_II PF14264.6 AMK78851.1 - 0.012 15.0 0.5 0.097 12.0 0.1 2.0 2 0 0 2 2 2 0 Glucosyl transferase GtrII TRIQK PF15168.6 AMK78851.1 - 0.037 13.9 1.0 0.05 13.5 0.1 1.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family YWFCY PF14293.6 AMK78851.1 - 0.12 12.7 0.1 0.47 10.8 0.1 2.0 1 0 0 1 1 1 0 YWFCY protein YppF PF14178.6 AMK78851.1 - 0.13 12.2 0.1 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 YppF-like protein T2SSE PF00437.20 AMK78852.1 - 3e-79 265.9 1.5 4.8e-79 265.3 1.5 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AMK78852.1 - 1.2e-24 86.6 4.8 4e-23 81.8 1.5 2.9 3 0 0 3 3 2 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_23 PF13476.6 AMK78852.1 - 0.00056 20.5 1.9 0.0031 18.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AMK78852.1 - 0.001 18.7 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK78852.1 - 0.0011 19.4 1.4 0.0048 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 AMK78852.1 - 0.0015 19.0 0.2 0.079 13.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AMK78852.1 - 0.0015 18.8 0.1 0.0098 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AMK78852.1 - 0.004 17.7 0.7 0.23 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AMK78852.1 - 0.019 15.5 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 AMK78852.1 - 0.045 13.8 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AMK78852.1 - 0.049 13.4 0.1 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AMK78852.1 - 0.051 13.9 0.8 0.13 12.6 0.2 2.1 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 AMK78852.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 AMK78852.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 AMK78852.1 - 0.11 12.4 5.1 1 9.3 0.4 3.9 3 2 1 4 4 4 0 NTPase AAA_11 PF13086.6 AMK78852.1 - 0.12 12.2 0.2 0.32 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AMK78852.1 - 0.12 12.0 0.2 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AMK78852.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_19 PF14559.6 AMK78853.1 - 3.2e-15 56.4 18.1 1.1e-06 29.0 0.2 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 AMK78853.1 - 7.6e-12 45.2 5.8 4.1e-08 33.3 1.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78853.1 - 1.6e-08 34.6 13.0 0.021 15.6 0.5 5.4 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78853.1 - 1.1e-07 31.3 13.3 0.045 13.9 0.9 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 AMK78853.1 - 4.6e-07 30.4 14.5 6.1e-06 26.8 2.8 4.1 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 AMK78853.1 - 5.7e-07 29.1 14.2 0.0072 16.1 1.7 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 AMK78853.1 - 2.7e-06 27.5 12.6 2e-05 24.8 4.0 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AMK78853.1 - 8.7e-06 25.4 8.5 0.17 12.0 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AMK78853.1 - 0.0006 20.0 6.5 0.054 13.7 2.0 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 AMK78853.1 - 0.00074 20.0 11.4 0.092 13.4 0.4 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 AMK78853.1 - 0.0015 17.5 2.5 0.0022 17.0 2.5 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.6 AMK78853.1 - 0.0048 17.0 6.2 1.7 9.0 0.0 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AMK78853.1 - 0.0062 16.8 6.6 0.24 11.8 0.2 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 AMK78853.1 - 0.0077 15.9 0.2 0.02 14.5 0.2 1.8 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 AMK78853.1 - 0.0077 15.9 12.2 4.5 7.0 1.6 4.7 3 2 1 4 4 4 1 TPR repeat TPR_10 PF13374.6 AMK78853.1 - 0.064 13.1 0.2 0.064 13.1 0.2 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 AMK78854.1 - 1.9e-25 89.8 0.3 4.1e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 AMK78854.1 - 1.6e-07 31.8 0.0 2.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK78854.1 - 5.5e-07 30.1 0.2 5.9e-06 26.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 AMK78854.1 - 0.00014 21.7 0.0 0.00031 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AMK78854.1 - 0.0015 18.5 0.0 0.004 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AMK78854.1 - 0.0024 17.3 0.3 0.077 12.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 AMK78854.1 - 0.003 17.5 0.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_19 PF13245.6 AMK78854.1 - 0.0046 17.3 0.2 4 7.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain PIF1 PF05970.14 AMK78854.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_11 PF13086.6 AMK78854.1 - 0.012 15.5 0.1 0.92 9.2 0.0 2.1 1 1 0 2 2 2 0 AAA domain PhoH PF02562.16 AMK78854.1 - 0.012 15.1 0.2 1.9 7.9 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein DUF2075 PF09848.9 AMK78854.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 AMK78854.1 - 0.02 15.1 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AMK78854.1 - 0.035 14.7 0.0 0.06 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 AMK78854.1 - 0.037 14.0 0.3 0.45 10.5 0.2 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AMK78854.1 - 0.043 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 AMK78854.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 AMK78854.1 - 0.077 13.5 0.2 0.76 10.3 0.0 2.3 3 0 0 3 3 3 0 ABC transporter TsaE PF02367.17 AMK78854.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 AMK78854.1 - 0.2 11.6 0.1 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 NTPase Secretin PF00263.21 AMK78855.1 - 2.1e-38 131.6 4.8 4.7e-38 130.5 4.8 1.6 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N_2 PF07655.13 AMK78855.1 - 4e-17 62.6 9.0 1.5e-16 60.7 9.0 2.1 1 0 0 1 1 1 1 Secretin N-terminal domain Secretin_N PF03958.17 AMK78855.1 - 0.00011 22.6 6.2 0.00082 19.7 6.2 2.4 1 1 0 1 1 1 1 Bacterial type II/III secretion system short domain STN PF07660.14 AMK78855.1 - 0.0037 17.0 0.0 0.0096 15.7 0.0 1.8 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain DUF4911 PF16256.5 AMK78855.1 - 0.013 15.5 0.3 0.071 13.1 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4911) T2SSB PF16537.5 AMK78856.1 - 3.5e-06 26.5 0.2 5e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Type II secretion system protein B T2SSC PF11356.8 AMK78856.1 - 0.076 12.9 0.1 0.089 12.7 0.1 1.3 1 1 0 1 1 1 0 Type II secretion system protein C T2SSM PF04612.12 AMK78857.1 - 1.9e-06 28.0 11.6 3.1e-05 24.1 8.0 2.1 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein M DUF1664 PF07889.12 AMK78857.1 - 0.032 14.3 1.3 0.068 13.2 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3247 PF11607.8 AMK78857.1 - 0.082 13.2 0.3 12 6.3 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3247) Zwint PF15556.6 AMK78857.1 - 0.19 11.2 9.3 0.27 10.7 9.3 1.2 1 0 0 1 1 1 0 ZW10 interactor DUF1525 PF07511.11 AMK78857.1 - 0.24 11.6 3.6 0.44 10.7 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) HU-CCDC81_bac_2 PF18175.1 AMK78857.1 - 0.63 10.0 3.9 2.5 8.0 0.0 3.2 4 1 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 PilN PF05137.13 AMK78858.1 - 5.2e-06 26.5 1.3 1.1e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 Fimbrial assembly protein (PilN) DUF4407 PF14362.6 AMK78858.1 - 0.0036 16.7 1.1 0.0051 16.2 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FH2 PF02181.23 AMK78858.1 - 0.0042 16.3 0.9 0.006 15.8 0.9 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF4349 PF14257.6 AMK78858.1 - 0.0079 15.7 1.9 0.012 15.1 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DPM3 PF08285.11 AMK78858.1 - 0.012 15.8 0.7 0.25 11.6 0.1 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Chorismate_synt PF01264.21 AMK78858.1 - 0.039 12.7 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase TPR_6 PF13174.6 AMK78858.1 - 0.052 14.2 3.8 0.082 13.6 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2730 PF10805.8 AMK78858.1 - 0.1 12.7 1.2 0.17 12.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.15 AMK78858.1 - 0.11 12.3 9.5 0.12 12.2 3.0 2.4 1 1 1 2 2 2 0 Septum formation initiator OmpH PF03938.14 AMK78858.1 - 0.14 12.5 7.9 0.24 11.7 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Acylphosphatase PF00708.18 AMK78858.1 - 0.15 12.5 0.0 4.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Acylphosphatase P22_portal PF16510.5 AMK78858.1 - 0.3 9.6 4.3 0.4 9.2 4.3 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein RskA PF10099.9 AMK78858.1 - 0.38 11.0 3.6 1.6 9.0 3.7 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CCDC92 PF14916.6 AMK78858.1 - 0.41 10.5 12.9 0.16 11.8 9.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function PilO PF04350.13 AMK78858.1 - 0.48 10.6 8.3 18 5.5 8.0 2.4 1 1 1 2 2 2 0 Pilus assembly protein, PilO Gp58 PF07902.11 AMK78858.1 - 1.2 7.3 7.1 2.2 6.4 7.1 1.4 1 1 0 1 1 1 0 gp58-like protein DUF3573 PF12097.8 AMK78858.1 - 1.8 7.3 7.9 2.5 6.8 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) PilM_2 PF11104.8 AMK78859.1 - 2.5e-08 33.3 0.0 3.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; Sod_Fe_C PF02777.18 AMK78860.1 - 1.4e-20 73.3 0.0 2.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AMK78860.1 - 0.00019 21.9 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UCR_Fe-S_N PF10399.9 AMK78860.1 - 0.00084 18.6 0.8 0.0016 17.7 0.8 1.4 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 AMK78860.1 - 0.0049 16.7 0.8 0.0049 16.7 0.8 2.3 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence Chromate_transp PF02417.15 AMK78861.1 - 3.8e-69 231.8 38.1 5.3e-35 120.9 17.3 2.3 2 0 0 2 2 2 2 Chromate transporter Chrome_Resist PF09828.9 AMK78862.1 - 1.7e-42 145.0 1.3 2e-42 144.7 0.5 1.5 2 0 0 2 2 2 1 Chromate resistance exported protein RTP1_C2 PF10304.9 AMK78862.1 - 0.096 12.4 0.3 0.24 11.1 0.3 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 DUF2207 PF09972.9 AMK78862.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CN_hydrolase PF00795.22 AMK78865.1 - 4.8e-24 85.1 0.1 7.6e-24 84.5 0.1 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Acetyltransf_1 PF00583.25 AMK78866.1 - 0.00027 21.2 0.0 0.00041 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AMK78866.1 - 0.036 14.1 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1283 PF06932.11 AMK78867.1 - 0.21 11.8 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Ub-RnfH PF03658.14 AMK78868.1 - 7e-31 106.5 0.1 7.9e-31 106.3 0.1 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin Polyketide_cyc PF03364.20 AMK78869.1 - 1.3e-25 90.1 0.0 1.5e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 AMK78869.1 - 1.8e-05 25.0 0.0 2.1e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SNF PF00209.18 AMK78870.1 - 4.4e-50 170.9 36.9 7.5e-29 100.8 8.9 2.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family SmpB PF01668.18 AMK78871.1 - 1.5e-57 193.5 0.8 1.8e-57 193.3 0.8 1.1 1 0 0 1 1 1 1 SmpB protein Isochorismatase PF00857.20 AMK78872.1 - 4.4e-28 98.6 0.0 5.2e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF4350 PF14258.6 AMK78872.1 - 0.17 12.3 0.8 0.43 11.0 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4350) ApbE PF02424.15 AMK78873.1 - 5.5e-75 252.2 0.0 6.6e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 ApbE family Laminin_II PF06009.12 AMK78873.1 - 0.062 13.3 0.5 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Laminin Domain II DUF2231 PF09990.9 AMK78874.1 - 1.2e-13 51.4 8.1 2.2e-13 50.5 8.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) Cyt_bd_oxida_I PF01654.17 AMK78874.1 - 0.25 9.9 5.4 0.91 8.1 1.7 2.0 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit I PRAI PF00697.22 AMK78875.1 - 3.2e-47 160.8 0.0 3.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase PALP PF00291.25 AMK78876.1 - 1.7e-47 162.2 1.2 2.2e-47 161.9 1.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UBM PF14377.6 AMK78876.1 - 0.089 12.3 0.8 0.23 11.0 0.8 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Trp_syntA PF00290.20 AMK78877.1 - 1e-86 290.0 0.1 1.2e-86 289.8 0.1 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 AMK78877.1 - 0.0016 17.9 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 AMK78877.1 - 0.0018 17.8 0.1 0.0028 17.1 0.1 1.4 1 0 0 1 1 1 1 PcrB family BtpA PF03437.15 AMK78877.1 - 0.0086 15.5 0.2 0.013 14.9 0.2 1.2 1 0 0 1 1 1 1 BtpA family Carboxyl_trans PF01039.22 AMK78878.1 - 1.5e-16 60.1 0.1 2.2e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 AMK78878.1 - 6.6e-12 45.3 4.0 9.9e-12 44.7 4.0 1.3 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain UPF0547 PF10571.9 AMK78878.1 - 0.012 15.7 1.3 3.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 AMK78878.1 - 0.028 13.8 0.9 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 AMK78878.1 - 0.036 14.2 0.5 0.066 13.4 0.5 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_Tnp_IS1595 PF12760.7 AMK78878.1 - 1.6 8.8 4.4 1.2 9.2 1.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Mur_ligase_M PF08245.12 AMK78879.1 - 5.9e-10 39.5 0.0 2.1e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AMK78879.1 - 1.7e-07 31.4 0.0 9.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain SPOR PF05036.13 AMK78880.1 - 8e-16 58.2 1.3 1.9e-15 57.0 1.3 1.7 1 0 0 1 1 1 1 Sporulation related domain Colicin_V PF02674.16 AMK78881.1 - 1.5e-38 132.0 13.2 1.7e-38 131.8 13.2 1.0 1 0 0 1 1 1 1 Colicin V production protein YiaAB PF05360.14 AMK78881.1 - 0.043 14.1 0.2 0.043 14.1 0.2 3.6 3 2 0 3 3 3 0 yiaA/B two helix domain PAP2 PF01569.21 AMK78881.1 - 2 8.2 9.3 0.47 10.2 3.5 2.4 1 1 1 2 2 2 0 PAP2 superfamily DUF2070 PF09843.9 AMK78881.1 - 6.7 4.9 9.3 7.5 4.7 9.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GATase_6 PF13522.6 AMK78882.1 - 8e-16 58.5 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AMK78882.1 - 1.9e-13 50.4 0.0 6.1e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AMK78882.1 - 3.1e-10 39.8 0.0 6.2e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AMK78882.1 - 3.3e-06 26.2 0.0 6.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 AMK78882.1 - 0.073 11.8 0.6 0.51 9.0 0.1 2.4 2 1 1 3 3 3 0 Glutamine amidotransferases class-II Cys_Met_Meta_PP PF01053.20 AMK78883.1 - 1.3e-143 478.1 0.0 1.5e-143 478.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 AMK78883.1 - 6.9e-10 38.6 0.0 9.4e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AMK78883.1 - 1.2e-08 34.3 0.0 1.8e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AMK78883.1 - 1.5e-08 34.3 0.1 6.8e-08 32.2 0.0 2.0 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 AMK78883.1 - 0.00068 18.6 0.0 0.00099 18.0 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 AMK78883.1 - 0.001 17.7 0.1 0.0017 17.0 0.1 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase PilZ PF07238.14 AMK78884.1 - 8.8e-13 48.5 0.2 4.5e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 PilZ domain DUF3016 PF11454.8 AMK78884.1 - 0.11 12.3 0.1 2.9 7.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3016) Glutaredoxin PF00462.24 AMK78885.1 - 1.8e-21 76.1 0.0 2.2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 AMK78885.1 - 0.00076 19.8 0.0 0.00088 19.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SpoOE-like PF09388.10 AMK78885.1 - 0.0072 16.2 0.0 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 Spo0E like sporulation regulatory protein SH3BGR PF04908.15 AMK78885.1 - 0.049 13.8 0.0 0.077 13.2 0.0 1.3 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Aldolase_II PF00596.21 AMK78886.1 - 8.1e-11 42.2 0.2 1.3e-10 41.5 0.2 1.3 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MscS_TM PF12794.7 AMK78887.1 - 2e-72 243.9 24.7 4.6e-72 242.7 24.7 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 MS_channel PF00924.18 AMK78887.1 - 1.8e-50 171.4 3.6 1.8e-50 171.4 3.6 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel MscS_porin PF12795.7 AMK78887.1 - 2.9e-22 79.4 49.4 2.9e-22 79.4 49.4 3.3 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain DUF485 PF04341.12 AMK78887.1 - 9 6.3 11.4 17 5.5 1.8 3.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ATP-cone PF03477.16 AMK78888.1 - 1.2e-15 57.9 0.1 1.7e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 ATP cone domain DUF2387 PF09526.10 AMK78888.1 - 0.024 14.8 0.3 0.038 14.1 0.3 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) BAG PF02179.16 AMK78888.1 - 0.032 14.7 0.4 0.056 13.9 0.0 1.6 2 0 0 2 2 2 0 BAG domain Zn_Tnp_IS1595 PF12760.7 AMK78888.1 - 0.095 12.7 1.0 0.17 11.9 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 AMK78888.1 - 0.11 12.9 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar RibD_C PF01872.17 AMK78889.1 - 2.6e-48 164.5 0.1 3.6e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AMK78889.1 - 2.5e-19 69.0 0.1 4.4e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AMK78889.1 - 2e-12 47.1 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 AMK78889.1 - 3.6e-05 23.6 0.0 0.0018 18.1 0.0 2.5 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 AMK78889.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DUF5334 PF17268.2 AMK78890.1 - 0.0073 16.6 0.1 0.0099 16.2 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5334) Lum_binding PF00677.17 AMK78891.1 - 8.6e-49 163.5 1.5 1.2e-26 92.5 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain DHBP_synthase PF00926.19 AMK78892.1 - 3.5e-84 281.1 1.0 4.2e-84 280.9 0.2 1.5 2 0 0 2 2 2 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AMK78892.1 - 1.5e-42 145.0 0.0 2.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II DMRL_synthase PF00885.19 AMK78893.1 - 1.1e-56 190.5 0.4 1.3e-56 190.4 0.4 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase NusB PF01029.18 AMK78894.1 - 5.8e-36 123.7 0.0 7.9e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 NusB family AIRS PF00586.24 AMK78895.1 - 5.2e-25 87.9 0.5 2.2e-24 85.9 0.3 2.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AMK78895.1 - 4.5e-08 33.4 0.0 7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain PgpA PF04608.13 AMK78896.1 - 1.9e-51 173.8 9.9 2.2e-51 173.6 9.9 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A FtsK_4TM PF13491.6 AMK78896.1 - 1.2 8.9 12.1 0.13 12.0 1.7 2.2 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Haem_degrading PF03928.14 AMK78897.1 - 1.6e-06 28.1 2.0 1.6e-06 28.1 2.0 2.1 2 1 0 2 2 2 1 Haem-degrading Sel1 PF08238.12 AMK78898.1 - 1.5e-63 209.8 43.2 4.4e-11 43.1 0.0 8.5 8 0 0 8 8 8 8 Sel1 repeat Trypsin_2 PF13365.6 AMK78898.1 - 4.5e-19 69.8 0.2 1.1e-18 68.5 0.2 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain RDD PF06271.12 AMK78898.1 - 1.9e-10 41.1 6.5 4e-10 40.1 6.5 1.4 1 0 0 1 1 1 1 RDD family Trypsin PF00089.26 AMK78898.1 - 6.7e-05 22.8 0.1 0.00027 20.8 0.1 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S3 PF00944.19 AMK78898.1 - 0.077 12.8 0.2 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Alphavirus core protein TPR_6 PF13174.6 AMK78898.1 - 0.15 12.7 10.2 12 6.8 0.5 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Helicase_C_3 PF13625.6 AMK78899.1 - 0.027 14.6 0.2 0.048 13.8 0.2 1.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain DnaB_bind PF10410.9 AMK78899.1 - 0.083 13.1 0.6 0.15 12.3 0.2 1.6 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF2018 PF09442.10 AMK78899.1 - 0.1 13.6 0.3 4.1 8.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) Phe_tRNA-synt_N PF02912.18 AMK78902.1 - 0.17 11.8 0.2 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Robl_LC7 PF03259.17 AMK78903.1 - 0.078 12.8 0.5 0.21 11.4 0.5 1.7 1 0 0 1 1 1 0 Roadblock/LC7 domain Nucleoporin_FG2 PF15967.5 AMK78904.1 - 0.19 10.2 0.1 0.23 10.0 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region HTH_3 PF01381.22 AMK78906.1 - 2.9e-07 30.4 0.0 5.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 AMK78906.1 - 0.00024 21.5 0.0 0.00041 20.7 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain TetR_N PF00440.23 AMK78906.1 - 0.0018 18.0 0.6 0.0072 16.1 0.2 2.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 AMK78906.1 - 0.0023 18.0 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 AMK78906.1 - 0.0035 17.6 0.0 0.0056 17.0 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AMK78906.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_1 PF00126.27 AMK78906.1 - 0.049 13.6 0.1 0.2 11.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 AMK78906.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_19 PF12844.7 AMK78906.1 - 0.075 13.1 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Gp49 PF05973.14 AMK78907.1 - 4.1e-07 30.1 0.0 5.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) Phage_integrase PF00589.22 AMK78908.1 - 6.5e-16 58.6 0.0 1.2e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 AMK78908.1 - 4.7e-12 46.1 0.0 4.7e-12 46.1 0.0 2.7 4 0 0 4 4 4 1 Arm DNA-binding domain Phage_integr_3 PF16795.5 AMK78908.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal phage integrase NuDC PF16273.5 AMK78908.1 - 0.51 10.9 4.5 1 10.0 4.5 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain HTH_Tnp_1 PF01527.20 AMK78909.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK78909.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK78909.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK78909.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK78909.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK78909.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit rve PF00665.26 AMK78910.1 - 2.4e-31 108.4 0.1 4.8e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK78910.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK78910.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK78910.1 - 3.1e-08 33.9 1.0 8.9e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK78910.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain Tox-PL-2 PF15643.6 AMK78910.1 - 0.097 12.8 0.0 0.86 9.8 0.0 2.4 2 1 0 2 2 2 0 Papain fold toxin 2 DUF3146 PF11344.8 AMK78911.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3146) rve PF00665.26 AMK78912.1 - 8.2e-16 58.3 0.0 2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_11 PF08279.12 AMK78912.1 - 0.00027 20.8 0.0 0.00074 19.4 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 AMK78912.1 - 0.00077 19.3 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 AMK78912.1 - 0.0025 17.6 0.0 0.02 14.7 0.0 2.4 3 0 0 3 3 3 1 HTH DNA binding domain HTH_DeoR PF08220.12 AMK78912.1 - 0.0077 15.9 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_36 PF13730.6 AMK78912.1 - 0.012 15.6 0.2 0.07 13.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 AMK78912.1 - 0.021 14.6 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 AMK78912.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 AMK78912.1 - 0.052 13.6 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.16 AMK78912.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 NUMOD1 PF07453.13 AMK78912.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_41 PF14502.6 AMK78912.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 AMK78912.1 - 0.1 12.4 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_23 PF13384.6 AMK78912.1 - 0.32 10.9 1.3 3 7.8 0.0 3.2 5 0 0 5 5 5 0 Homeodomain-like domain IstB_IS21 PF01695.17 AMK78913.1 - 6.6e-58 195.4 0.4 5.3e-57 192.4 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK78913.1 - 1.4e-09 38.1 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK78913.1 - 2e-05 24.2 0.1 2.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AFG1_ATPase PF03969.16 AMK78913.1 - 0.0024 16.8 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK78913.1 - 0.0073 16.0 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 AMK78913.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 AMK78913.1 - 0.008 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 AMK78913.1 - 0.016 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 AMK78913.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 AMK78913.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 AMK78913.1 - 0.029 14.3 1.8 1.2 9.1 0.0 2.7 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 AMK78913.1 - 0.031 13.9 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 AMK78913.1 - 0.035 13.6 0.2 0.066 12.7 0.2 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 AMK78913.1 - 0.049 13.0 0.1 0.087 12.2 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 AMK78913.1 - 0.049 13.9 0.4 0.31 11.3 0.3 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AMK78913.1 - 0.058 13.1 0.3 0.12 12.1 0.3 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 AMK78913.1 - 0.13 11.6 0.1 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 AMK78913.1 - 0.19 11.5 0.4 0.41 10.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK78913.1 - 0.35 11.2 1.7 0.99 9.7 1.1 2.0 1 1 1 2 2 2 0 AAA domain CobA_CobO_BtuR PF02572.15 AMK78913.1 - 0.68 10.2 3.7 6.3 7.0 1.6 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PrpF PF04303.13 AMK78914.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 PrpF protein Glyco_hydro_30 PF02055.16 AMK78917.1 - 6.9e-45 153.5 0.0 8.6e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 AMK78917.1 - 4.3e-13 49.3 0.0 8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 AMK78917.1 - 4e-12 46.0 0.0 9.8e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 AMK78917.1 - 0.00011 22.0 0.0 0.026 14.1 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_36 PF17167.4 AMK78918.1 - 0.0032 16.2 0.0 0.0046 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Nop PF01798.18 AMK78918.1 - 0.089 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Glyco_transf_36 PF06165.11 AMK78918.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 36 OEP PF02321.18 AMK78919.1 - 1.2e-55 188.3 26.4 1.7e-28 99.7 8.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein ACR_tran PF00873.19 AMK78920.1 - 0 1150.3 19.0 0 1150.1 19.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK78920.1 - 1.5e-11 43.8 14.7 1.5e-11 43.8 14.7 2.7 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 AMK78920.1 - 1e-06 28.3 16.6 1e-06 28.3 16.6 2.6 3 0 0 3 3 3 1 Protein export membrane protein DUF4407 PF14362.6 AMK78920.1 - 0.028 13.8 7.9 0.059 12.7 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Patched PF02460.18 AMK78920.1 - 8.4 4.3 27.1 0.0028 15.8 13.3 1.9 2 0 0 2 2 2 0 Patched family HlyD_D23 PF16576.5 AMK78921.1 - 7.4e-20 71.1 0.1 8.7e-19 67.6 0.1 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AMK78921.1 - 5.9e-14 51.6 0.1 1.5e-10 40.7 0.1 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 AMK78921.1 - 7.5e-09 36.3 1.1 0.0012 19.5 0.1 3.7 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AMK78921.1 - 0.00042 20.1 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.20 AMK78921.1 - 0.0021 17.9 0.2 0.72 9.8 0.1 2.3 2 0 0 2 2 2 2 HlyD membrane-fusion protein of T1SS TetR_C_7 PF14246.6 AMK78922.1 - 1.1e-27 96.5 0.4 4.7e-27 94.4 0.8 1.8 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 AMK78922.1 - 9.2e-15 54.2 0.3 3.2e-14 52.4 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 AMK78922.1 - 0.00019 21.7 1.5 0.00034 20.9 1.1 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 AMK78922.1 - 0.092 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 AMK78922.1 - 0.095 12.7 0.0 0.6 10.1 0.0 2.1 2 0 0 2 2 2 0 HTH domain Polyketide_cyc2 PF10604.9 AMK78923.1 - 1.4e-21 77.3 0.0 1.6e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Tissue_fac PF01108.17 AMK78923.1 - 0.13 12.1 0.1 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Tissue factor Response_reg PF00072.24 AMK78924.1 - 3.1e-27 95.0 0.0 4.3e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK78924.1 - 1.1e-12 47.3 0.0 1.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AMK78924.1 - 0.0043 16.8 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AMK78924.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 AMK78924.1 - 0.021 14.8 0.0 0.075 13.1 0.0 2.0 1 1 0 1 1 1 0 Winged helix-turn helix 3HCDH_RFF PF18321.1 AMK78924.1 - 0.024 15.1 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HTH_30 PF13556.6 AMK78924.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 AMK78924.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family PQQ PF01011.21 AMK78925.1 - 9.5e-32 107.4 13.1 2.4e-06 27.2 0.0 7.6 8 0 0 8 8 8 6 PQQ enzyme repeat PQQ_2 PF13360.6 AMK78925.1 - 3.7e-16 59.4 0.8 1.2e-09 38.2 0.0 3.3 3 1 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 AMK78925.1 - 2.7e-10 40.4 17.3 0.016 15.7 0.2 6.6 7 0 0 7 7 7 5 PQQ-like domain Cu_amine_oxidN2 PF02727.16 AMK78925.1 - 0.19 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain SBP_bac_3 PF00497.20 AMK78926.1 - 2.1e-18 66.6 0.2 2.7e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 AMK78926.1 - 0.038 13.6 0.1 2.2 7.8 0.1 2.3 2 1 1 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF2990 PF11693.8 AMK78926.1 - 0.06 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) Pkip-1 PF06878.11 AMK78926.1 - 0.076 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Pkip-1 protein Cytochrome_CBB3 PF13442.6 AMK78927.1 - 2.2e-09 37.5 0.1 3.5e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 AMK78927.1 - 7.3e-06 27.0 0.3 7.9e-05 23.7 0.3 2.3 1 1 0 1 1 1 1 Cytochrome c MDH PF02315.16 AMK78928.1 - 5.6e-43 144.9 0.1 6.2e-43 144.8 0.1 1.0 1 0 0 1 1 1 1 Methanol dehydrogenase beta subunit AAA_3 PF07726.11 AMK78929.1 - 3.6e-26 91.6 0.0 6.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AMK78929.1 - 6.6e-14 52.1 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 AMK78929.1 - 6.3e-12 45.2 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain RuvB_N PF05496.12 AMK78929.1 - 3.7e-05 23.5 0.0 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AMK78929.1 - 6.2e-05 23.0 0.1 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 AMK78929.1 - 0.00016 22.1 0.0 0.00054 20.4 0.0 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AMK78929.1 - 0.00035 21.1 0.0 0.00047 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK78929.1 - 0.00058 20.2 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AMK78929.1 - 0.00086 19.7 0.0 0.0035 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AMK78929.1 - 0.0012 18.3 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 AMK78929.1 - 0.0044 16.9 0.3 0.01 15.8 0.3 1.5 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 AMK78929.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 AMK78929.1 - 0.019 14.9 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 AMK78929.1 - 0.023 14.4 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AMK78929.1 - 0.025 14.3 0.4 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 AMK78929.1 - 0.032 14.8 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 AMK78929.1 - 0.053 13.2 0.6 0.094 12.4 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AMK78929.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AMK78929.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3584 PF12128.8 AMK78929.1 - 0.12 9.8 0.1 0.17 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_18 PF13238.6 AMK78929.1 - 0.13 12.8 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 AMK78929.1 - 0.18 10.9 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 AMK78929.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF58 PF01882.18 AMK78931.1 - 0.0093 16.2 0.0 0.049 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_CoxE PF05762.14 AMK78931.1 - 0.035 13.5 0.1 2.5 7.4 0.0 2.5 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein VWA_2 PF13519.6 AMK78931.1 - 0.19 12.4 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 AMK78933.1 - 1.1e-14 54.9 0.0 2.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 AMK78933.1 - 9.7e-09 35.7 0.0 1.4e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 AMK78933.1 - 0.027 13.7 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) TPR_1 PF00515.28 AMK78934.1 - 0.00064 19.4 2.2 4.5 7.2 0.4 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78934.1 - 0.00089 19.2 4.4 1.9 8.8 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78934.1 - 0.022 14.4 7.2 1.7 8.4 0.0 3.3 3 1 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 AMK78934.1 - 0.055 14.3 1.6 0.055 14.3 1.6 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 AMK78934.1 - 0.089 13.0 3.6 8.8 6.8 0.2 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF2809 PF10990.8 AMK78934.1 - 0.14 12.8 0.5 0.25 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) TPR_16 PF13432.6 AMK78934.1 - 0.19 12.4 7.3 0.37 11.5 1.2 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 AMK78934.1 - 2.3 8.8 12.8 1.4 9.5 1.0 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 AMK78934.1 - 4.2 7.4 8.1 84 3.2 2.8 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat VWA_2 PF13519.6 AMK78935.1 - 1.7e-11 44.7 0.0 1.4e-10 41.8 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain SAM_Exu PF18609.1 AMK78935.1 - 0.034 14.2 0.2 0.081 13.0 0.2 1.6 1 0 0 1 1 1 0 Exuperantia SAM-like domain DUF3072 PF11272.8 AMK78935.1 - 0.29 11.1 2.2 0.29 11.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Plug PF07715.15 AMK78936.1 - 5.1e-11 43.1 2.2 5.1e-11 43.1 2.2 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain TSC22 PF01166.18 AMK78936.1 - 0.064 13.6 1.0 0.15 12.4 1.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1501 PF07394.12 AMK78937.1 - 6.9e-130 433.6 0.0 8e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Sulfatase PF00884.23 AMK78937.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Sulfatase Phosphodiest PF01663.22 AMK78937.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1040 PF06288.13 AMK78937.1 - 0.072 13.5 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) PSD1 PF07587.11 AMK78938.1 - 1.1e-92 310.0 0.1 2e-92 309.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) PSCyt2 PF07583.11 AMK78938.1 - 9.8e-82 273.9 0.9 5.8e-81 271.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1549) EAL PF00563.20 AMK78939.1 - 6e-44 150.3 0.1 9.2e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 EAL domain YkuI_C PF10388.9 AMK78939.1 - 4.1e-16 59.2 0.4 6.9e-16 58.5 0.4 1.4 1 0 0 1 1 1 1 EAL-domain associated signalling protein domain AIRC PF00731.20 AMK78939.1 - 0.049 13.2 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 AIR carboxylase KIP1 PF07765.12 AMK78939.1 - 0.095 12.8 0.1 0.6 10.3 0.1 2.2 2 0 0 2 2 2 0 KIP1-like protein Molybdopterin PF00384.22 AMK78940.1 - 1.7e-80 271.1 0.0 2.2e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AMK78940.1 - 2.1e-27 95.4 0.0 5e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AMK78940.1 - 6.8e-19 67.6 0.5 1.6e-18 66.4 0.5 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 AMK78940.1 - 2.4e-12 47.0 1.2 1.3e-11 44.6 0.9 2.4 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Pyr_redox_2 PF07992.14 AMK78941.1 - 7.2e-53 179.7 0.1 8.9e-53 179.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 AMK78941.1 - 1e-21 76.6 0.6 3.2e-21 75.0 0.2 2.1 3 0 0 3 3 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 AMK78941.1 - 7.9e-21 74.4 0.1 7.5e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AMK78941.1 - 4.6e-09 36.0 0.0 7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK78941.1 - 8.2e-06 25.6 0.3 0.022 14.3 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AMK78941.1 - 1.1e-05 24.3 0.0 0.16 10.7 0.0 3.6 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_9 PF13454.6 AMK78941.1 - 2.3e-05 24.5 1.3 0.25 11.3 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 AMK78941.1 - 0.00017 22.0 0.0 0.037 14.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 AMK78941.1 - 0.00054 20.1 0.1 0.09 13.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 AMK78941.1 - 0.0017 17.7 0.6 0.029 13.7 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 AMK78941.1 - 0.0046 16.1 0.6 0.47 9.5 0.2 3.1 3 1 1 4 4 4 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 AMK78941.1 - 0.005 16.9 0.6 0.53 10.4 0.1 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 AMK78941.1 - 0.0083 15.0 0.3 0.15 10.9 0.0 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 AMK78941.1 - 0.0086 15.2 0.3 1.1 8.2 0.0 2.9 2 1 1 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.18 AMK78941.1 - 0.0097 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AMK78941.1 - 0.01 15.1 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 AMK78941.1 - 0.068 13.4 0.1 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 AMK78941.1 - 0.11 11.8 0.5 11 5.2 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 AMK78941.1 - 0.14 11.4 0.0 2.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 AMK78941.1 - 0.15 11.1 1.8 1.5 7.8 0.4 2.4 2 0 0 2 2 2 0 FAD binding domain Alginate_exp PF13372.6 AMK78942.1 - 1.8e-07 30.3 3.5 3.2e-07 29.5 3.5 1.5 1 0 0 1 1 1 1 Alginate export ABC_tran PF00005.27 AMK78943.1 - 1.1e-59 200.8 0.0 1e-29 103.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 AMK78943.1 - 7.6e-08 32.7 0.0 0.01 16.1 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AMK78943.1 - 3.2e-07 30.9 0.1 0.019 15.4 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 AMK78943.1 - 8.1e-07 29.5 2.5 0.00023 21.6 0.1 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AMK78943.1 - 1e-06 28.3 2.9 0.024 14.4 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 AMK78943.1 - 7.2e-06 26.0 0.4 6.3 6.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AMK78943.1 - 1.5e-05 25.0 1.8 0.12 12.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 AMK78943.1 - 6.7e-05 23.1 1.7 0.43 10.7 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 AMK78943.1 - 0.00016 21.3 0.1 0.44 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 AMK78943.1 - 0.00044 19.5 2.0 0.22 10.7 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain SMC_N PF02463.19 AMK78943.1 - 0.0012 18.3 2.2 3 7.2 0.1 3.7 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK78943.1 - 0.0013 19.3 0.7 0.82 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AMK78943.1 - 0.0015 18.3 0.1 0.46 10.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain ABC_ATPase PF09818.9 AMK78943.1 - 0.0025 16.7 5.2 0.25 10.1 0.0 3.9 4 0 0 4 4 4 1 Predicted ATPase of the ABC class MobB PF03205.14 AMK78943.1 - 0.0045 16.9 0.4 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 AMK78943.1 - 0.0051 17.4 0.3 0.67 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AMK78943.1 - 0.0057 16.6 0.9 0.39 10.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 AMK78943.1 - 0.0066 16.2 0.6 2.5 7.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 AMK78943.1 - 0.0083 16.2 2.3 1.6 8.8 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase PRK PF00485.18 AMK78943.1 - 0.011 15.5 4.0 0.93 9.2 0.3 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 AMK78943.1 - 0.011 15.3 1.0 0.13 11.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 AMK78943.1 - 0.021 14.7 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 AMK78943.1 - 0.024 14.8 0.4 4.7 7.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 AMK78943.1 - 0.035 13.8 0.8 2.5 7.7 0.2 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.16 AMK78943.1 - 0.035 13.5 0.3 4 6.8 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 AMK78943.1 - 0.037 13.4 2.1 6.6 6.0 0.0 3.1 2 1 1 3 3 3 0 KaiC T2SSE PF00437.20 AMK78943.1 - 0.045 12.8 0.3 0.5 9.4 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 AMK78943.1 - 0.055 13.9 0.1 13 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 AMK78943.1 - 0.059 13.1 1.3 4 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AMK78943.1 - 0.08 12.7 0.9 20 4.9 0.1 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein RecC_C PF17946.1 AMK78943.1 - 0.11 12.3 0.2 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 RecC C-terminal domain DUF87 PF01935.17 AMK78943.1 - 0.13 12.3 1.7 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 AMK78943.1 - 0.14 11.4 0.2 13 5.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 AMK78943.1 - 0.14 11.7 0.3 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 AMK78943.1 - 0.15 12.0 0.4 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 AMK78943.1 - 0.17 11.2 1.0 1.5 8.1 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 AMK78943.1 - 0.18 11.9 0.1 24 5.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AMK78943.1 - 0.19 11.2 0.2 13 5.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PEPCK_ATP PF01293.20 AMK78943.1 - 0.23 10.1 0.0 14 4.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_5 PF07728.14 AMK78943.1 - 0.24 11.4 0.9 15 5.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 AMK78943.1 - 0.29 11.5 1.7 18 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 AMK78943.1 - 0.44 10.8 6.0 4.7 7.4 0.1 3.4 4 0 0 4 4 3 0 AAA domain ATPase_2 PF01637.18 AMK78943.1 - 0.57 10.1 2.5 31 4.4 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 AMK78943.1 - 0.66 10.4 3.6 15 6.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain BPD_transp_1 PF00528.22 AMK78944.1 - 1.9e-22 79.9 11.0 1.9e-22 79.9 11.0 2.2 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component PrgI PF12666.7 AMK78944.1 - 0.55 11.0 0.0 0.55 11.0 0.0 3.0 3 1 0 3 3 3 0 PrgI family protein NMT1_2 PF13379.6 AMK78945.1 - 5.4e-99 331.0 0.3 7e-99 330.6 0.3 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 AMK78945.1 - 4.8e-05 23.4 0.0 0.00016 21.7 0.0 1.9 2 0 0 2 2 2 1 NMT1/THI5 like Pro_CA PF00484.19 AMK78946.1 - 1e-11 45.4 0.0 1.8e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase LysR_substrate PF03466.20 AMK78947.1 - 1.5e-36 125.7 0.0 2.4e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK78947.1 - 7.1e-17 61.1 0.1 1.3e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 AMK78947.1 - 0.053 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 HTH domain RDM PF11002.8 AMK78948.1 - 0.0009 19.2 0.3 0.1 12.6 0.0 2.7 2 1 0 2 2 2 2 RFPL defining motif (RDM) FliS PF02561.14 AMK78949.1 - 0.00093 19.5 1.2 0.11 12.8 0.1 2.2 2 0 0 2 2 2 2 Flagellar protein FliS YfdX PF10938.8 AMK78949.1 - 0.0023 17.9 3.7 0.082 12.8 0.1 2.2 2 0 0 2 2 2 2 YfdX protein TPR_16 PF13432.6 AMK78949.1 - 0.067 13.9 0.2 1.3 9.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TipAS PF07739.13 AMK78949.1 - 0.12 12.9 0.2 0.17 12.4 0.2 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain TPR_8 PF13181.6 AMK78949.1 - 0.25 11.6 2.4 0.88 9.9 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat IMD PF08397.11 AMK78950.1 - 0.0028 17.1 1.0 0.0096 15.3 0.9 1.7 1 1 1 2 2 2 1 IRSp53/MIM homology domain PI3K_P85_iSH2 PF16454.5 AMK78950.1 - 0.0035 17.0 1.0 0.0058 16.3 1.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tektin PF03148.14 AMK78950.1 - 0.0072 15.1 0.2 0.0095 14.7 0.2 1.1 1 0 0 1 1 1 1 Tektin family Allexi_40kDa PF05549.11 AMK78950.1 - 0.025 14.1 0.5 0.036 13.6 0.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1664 PF07889.12 AMK78950.1 - 0.033 14.2 1.3 0.069 13.2 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 AMK78950.1 - 0.067 13.1 0.2 4.3 7.2 0.0 1.9 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain ORF6C PF10552.9 AMK78950.1 - 0.085 12.9 0.2 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 ORF6C domain Phasin PF05597.11 AMK78950.1 - 0.14 12.1 1.2 0.26 11.3 0.6 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DDE_Tnp_1 PF01609.21 AMK78951.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK78951.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK78951.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK78951.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK78951.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK78951.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK78951.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK78951.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK78951.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK78951.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK78951.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK78951.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK78951.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain PfkB PF00294.24 AMK78952.1 - 5.3e-47 160.6 0.0 8.8e-47 159.9 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RLAN PF14401.6 AMK78953.1 - 1.2e-50 171.1 0.1 1.9e-50 170.4 0.1 1.3 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain RimK PF08443.11 AMK78953.1 - 5.7e-08 32.6 0.0 2.6e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 AMK78953.1 - 8.3e-07 28.7 0.0 2.4e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AMK78953.1 - 2.9e-06 27.4 0.0 9.6e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 AMK78953.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 AMK78953.1 - 0.012 14.9 0.0 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Synapsin_C PF02750.14 AMK78953.1 - 0.14 11.7 0.1 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Synapsin, ATP binding domain DUF2817 PF10994.8 AMK78954.1 - 1.5e-86 290.9 0.0 1.7e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) DUF3335 PF11814.8 AMK78955.1 - 7.6e-88 293.3 0.0 1e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase_C39 like family Acetyltransf_1 PF00583.25 AMK78955.1 - 1.5e-18 67.1 0.0 4.6e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AMK78955.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AMK78955.1 - 2.5e-10 40.6 0.0 5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 AMK78955.1 - 1e-06 28.8 0.0 0.00054 20.0 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 AMK78955.1 - 1.3e-06 28.3 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 AMK78955.1 - 0.00023 21.9 0.0 0.00062 20.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C39_2 PF13529.6 AMK78955.1 - 0.00028 21.5 0.1 0.014 16.0 0.1 2.2 1 1 0 1 1 1 1 Peptidase_C39 like family Acetyltransf_4 PF13420.7 AMK78955.1 - 0.00072 19.7 0.0 0.0038 17.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Peptidase_C70 PF12385.8 AMK78955.1 - 0.002 18.1 0.1 0.082 12.9 0.0 2.3 2 0 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 Acetyltransf_CG PF14542.6 AMK78955.1 - 0.0039 17.3 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 AMK78955.1 - 0.0051 16.5 0.0 0.11 12.1 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 AMK78955.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative acetyl-transferase Phytochelatin PF05023.14 AMK78955.1 - 0.032 13.4 0.1 0.067 12.4 0.1 1.4 1 1 0 1 1 1 0 Phytochelatin synthase Peptidase_C12 PF01088.21 AMK78955.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Aminotran_1_2 PF00155.21 AMK78956.1 - 1.5e-54 185.6 0.0 1.6e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 AMK78956.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 AMK78956.1 - 0.068 11.7 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AMK78956.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Homoserine_dh PF00742.19 AMK78957.1 - 5.5e-64 215.2 0.1 1.6e-63 213.8 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 AMK78957.1 - 2.1e-18 67.1 0.5 4.9e-18 65.9 0.5 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 AMK78957.1 - 3.4e-12 45.9 0.0 1.2e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 AMK78957.1 - 0.00031 21.3 0.0 0.00096 19.7 0.0 1.9 1 1 0 1 1 1 1 ACT domain Sacchrp_dh_NADP PF03435.18 AMK78957.1 - 0.0042 17.4 1.4 0.011 16.0 1.4 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ACT_6 PF13740.6 AMK78957.1 - 0.0087 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 AMK78957.1 - 0.019 14.8 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 ACT domain GFO_IDH_MocA PF01408.22 AMK78957.1 - 0.02 15.7 0.1 0.044 14.6 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2478 PF10649.9 AMK78957.1 - 0.052 13.2 0.2 0.86 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) PALP PF00291.25 AMK78958.1 - 4.4e-65 220.0 0.6 5.1e-65 219.8 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DHHA1 PF02272.19 AMK78959.1 - 2.1e-27 96.2 0.2 6.4e-27 94.7 0.1 1.9 2 0 0 2 2 2 1 DHHA1 domain RecJ_OB PF17768.1 AMK78959.1 - 5.9e-19 68.3 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 AMK78959.1 - 1.6e-08 34.7 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 DHH family Glyco_transf_4 PF13439.6 AMK78959.1 - 0.0031 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Peripla_BP_6 PF13458.6 AMK78959.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Dict-STAT-coil PF09267.10 AMK78959.1 - 0.18 12.2 0.3 0.4 11.1 0.3 1.6 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil PMT_2 PF13231.6 AMK78960.1 - 2.1e-29 102.8 21.1 2.1e-29 102.8 21.1 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CECR6_TMEM121 PF14997.6 AMK78960.1 - 0.9 9.3 7.2 0.13 12.1 0.2 2.8 2 1 1 3 3 3 0 CECR6/TMEM121 family DUF2142 PF09913.9 AMK78960.1 - 9 5.0 22.6 3 6.6 19.4 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) PAP2 PF01569.21 AMK78961.1 - 6.3e-18 64.9 6.0 6.3e-18 64.9 6.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AMK78961.1 - 2.5 7.8 22.3 2.8 7.6 16.8 2.7 1 1 1 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 AMK78961.1 - 3.3 8.3 12.2 0.72 10.4 7.3 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF188 PF02639.14 AMK78962.1 - 2.2e-43 147.0 0.0 2.5e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 DHDPS PF00701.22 AMK78963.1 - 9.2e-105 349.5 0.1 1e-104 349.3 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Lipoprotein_18 PF06804.11 AMK78964.1 - 1.3e-14 54.0 0.1 1.8e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 NlpB/DapX lipoprotein GATase_5 PF13507.6 AMK78965.1 - 4.6e-103 343.8 0.0 6.8e-103 343.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 AMK78965.1 - 1.1e-38 132.8 0.5 3.4e-25 89.0 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 AMK78965.1 - 5.3e-33 113.4 0.0 9.6e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 AMK78965.1 - 5.4e-24 84.5 0.0 1.7e-23 82.9 0.0 2.0 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain HisKA_3 PF07730.13 AMK78966.1 - 9.3e-13 48.5 4.4 9.4e-13 48.5 2.0 2.3 2 0 0 2 2 2 1 Histidine kinase LapD_MoxY_N PF16448.5 AMK78966.1 - 1.6e-09 37.7 4.0 2.6e-09 37.0 0.2 2.5 2 0 0 2 2 2 1 LapD/MoxY periplasmic domain HATPase_c PF02518.26 AMK78966.1 - 2e-06 28.2 0.1 1.4e-05 25.6 0.1 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AMK78966.1 - 8.7e-05 22.8 0.1 0.00098 19.5 0.0 2.5 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 AMK78966.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DNA_repr_REX1B PF14966.6 AMK78966.1 - 0.0033 18.0 1.7 0.0054 17.4 0.5 2.0 2 0 0 2 2 2 1 DNA repair REX1-B HATPase_c_3 PF13589.6 AMK78966.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YycH PF07435.11 AMK78966.1 - 0.067 12.1 0.7 0.11 11.5 0.7 1.2 1 0 0 1 1 1 0 YycH protein YtpI PF14007.6 AMK78966.1 - 0.095 12.8 0.7 0.72 10.0 0.5 2.2 2 0 0 2 2 2 0 YtpI-like protein Response_reg PF00072.24 AMK78967.1 - 2.1e-26 92.3 0.0 3.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK78967.1 - 3.8e-13 48.7 0.0 1.1e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AMK78967.1 - 0.0016 18.2 0.1 0.055 13.3 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain Terminase_5 PF06056.12 AMK78967.1 - 0.0027 17.6 0.0 0.0085 16.0 0.0 1.9 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_40 PF14493.6 AMK78967.1 - 0.0039 17.6 0.1 0.01 16.3 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AMK78967.1 - 0.081 12.7 0.2 0.84 9.4 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HDOD PF08668.12 AMK78968.1 - 1.1e-45 155.6 0.0 1.4e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 HDOD domain DUF3983 PF13137.6 AMK78968.1 - 0.064 13.1 1.1 3.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) MCPsignal PF00015.21 AMK78969.1 - 2.2e-45 154.5 41.4 1.2e-44 152.1 27.2 2.8 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3365 PF11845.8 AMK78969.1 - 2.7e-31 109.0 0.0 2.7e-31 109.0 0.0 3.3 2 1 0 2 2 1 1 Protein of unknown function (DUF3365) HAMP PF00672.25 AMK78969.1 - 1.5e-08 34.9 0.3 1e-06 29.0 0.0 3.8 3 1 2 5 5 4 1 HAMP domain DUF3450 PF11932.8 AMK78969.1 - 0.003 16.9 6.6 0.003 16.9 6.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) GARP PF16731.5 AMK78969.1 - 0.0088 15.8 7.8 0.0088 15.8 7.8 2.8 1 1 0 2 2 2 1 Glutamic acid/alanine-rich protein of Trypanosoma Fib_alpha PF08702.10 AMK78969.1 - 0.038 14.2 18.0 0.86 9.8 4.0 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 AMK78969.1 - 0.24 10.9 8.9 0.24 10.9 2.1 2.2 2 0 0 2 2 2 0 Leucine zipper DALR_2 PF09190.11 AMK78969.1 - 0.26 11.8 2.4 26 5.4 0.0 3.5 3 0 0 3 3 2 0 DALR domain Laminin_II PF06009.12 AMK78969.1 - 0.29 11.1 26.3 0.066 13.2 7.7 3.3 2 1 1 3 3 3 0 Laminin Domain II TMPIT PF07851.13 AMK78969.1 - 1.1 8.4 10.4 2.6 7.2 1.0 2.6 2 0 0 2 2 2 0 TMPIT-like protein Snapin_Pallidin PF14712.6 AMK78969.1 - 1.2 9.7 9.3 2.8 8.4 0.2 4.0 4 1 0 4 4 3 0 Snapin/Pallidin Med15_fungi PF05397.12 AMK78969.1 - 1.4 9.2 5.0 5 7.4 0.1 3.3 2 1 1 3 3 3 0 Mediator complex subunit 15 GLE1 PF07817.13 AMK78969.1 - 1.8 7.7 9.5 0.14 11.3 1.6 2.5 3 0 0 3 3 3 0 GLE1-like protein BLOC1_2 PF10046.9 AMK78969.1 - 1.8 8.9 18.0 5.7 7.3 0.2 4.9 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.20 AMK78969.1 - 2.3 7.5 17.3 1.6 8.1 4.8 2.6 2 1 0 2 2 2 0 Tropomyosin DUF5344 PF17279.2 AMK78969.1 - 7.1 7.3 13.7 1.4 9.5 0.2 4.4 2 2 2 4 4 4 0 Family of unknown function (DUF5344) DUF745 PF05335.13 AMK78969.1 - 8.3 6.1 29.7 0.63 9.7 8.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 AMK78969.1 - 8.8 6.7 27.4 0.2 11.9 4.0 4.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1690 PF07956.11 AMK78969.1 - 9.5 6.6 14.8 17 5.9 2.8 2.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DLH PF01738.18 AMK78970.1 - 1.3e-43 149.0 0.0 1.5e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 AMK78970.1 - 2.5e-07 30.7 0.0 4.4e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 AMK78970.1 - 4.4e-07 30.0 1.6 0.0042 17.0 0.9 3.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 AMK78970.1 - 4.8e-06 26.2 0.0 0.022 14.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AMK78970.1 - 9.2e-05 21.8 0.8 0.15 11.3 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 AMK78970.1 - 0.00052 18.8 0.0 0.0024 16.6 0.0 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 AMK78970.1 - 0.00065 18.6 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 AMK78970.1 - 0.0013 18.4 0.7 1.3 8.6 0.1 2.7 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AMK78970.1 - 0.0029 18.3 2.4 0.043 14.4 2.7 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 AMK78970.1 - 0.041 13.5 0.0 4.1 6.9 0.0 2.6 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 AMK78970.1 - 0.064 12.9 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 AMK78970.1 - 0.12 12.2 0.3 0.34 10.7 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DNA_topoisoIV PF00521.20 AMK78971.1 - 4.6e-154 513.4 0.0 5.8e-154 513.1 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AMK78971.1 - 9.1e-75 246.0 12.1 2.1e-13 49.5 0.1 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Aminotran_5 PF00266.19 AMK78972.1 - 3e-58 197.6 0.0 3.4e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V PDT PF00800.18 AMK78973.1 - 2.7e-60 203.3 0.2 3.6e-60 202.9 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 AMK78973.1 - 5.2e-22 78.0 0.3 8.6e-22 77.3 0.3 1.4 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 AMK78973.1 - 1.9e-14 53.1 0.0 8.9e-14 51.0 0.0 2.1 2 0 0 2 2 2 1 ACT domain Aminotran_1_2 PF00155.21 AMK78974.1 - 2.7e-52 178.1 0.0 3.1e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AMK78974.1 - 3.8e-05 22.8 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AMK78974.1 - 0.001 17.7 0.0 0.0016 17.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 AMK78974.1 - 0.26 10.1 0.0 0.47 9.3 0.0 1.3 1 0 0 1 1 1 0 Allinase PDH PF02153.17 AMK78975.1 - 5.6e-71 238.6 0.0 6.4e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 AMK78975.1 - 5.1e-06 27.0 0.0 1.2e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 AMK78975.1 - 0.00066 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 AMK78975.1 - 0.0014 18.9 0.0 0.0024 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AMK78975.1 - 0.0016 18.5 0.2 0.031 14.3 0.2 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 AMK78975.1 - 0.0023 18.0 0.0 0.0055 16.8 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 AMK78975.1 - 0.0034 18.2 0.0 0.021 15.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 AMK78975.1 - 0.013 15.4 0.5 7.1 6.5 0.5 3.0 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Meth_synt_2 PF01717.18 AMK78975.1 - 0.023 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain ApbA PF02558.16 AMK78975.1 - 0.065 12.9 0.2 0.18 11.5 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 AMK78975.1 - 0.12 12.4 0.2 1.7 8.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase EPSP_synthase PF00275.20 AMK78976.1 - 1.3e-124 416.1 0.0 1.6e-124 415.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Cytidylate_kin PF02224.18 AMK78977.1 - 7.4e-69 231.7 0.6 8.4e-69 231.5 0.6 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 AMK78977.1 - 1.5e-05 25.2 0.8 9.5e-05 22.6 0.8 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 AMK78977.1 - 0.00041 20.9 0.2 0.085 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AMK78977.1 - 0.001 19.2 0.1 0.015 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 AMK78977.1 - 0.001 19.5 0.3 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 AMK78977.1 - 0.014 15.5 1.6 0.058 13.5 0.0 2.3 3 0 0 3 3 3 0 Shikimate kinase ADK PF00406.22 AMK78977.1 - 0.017 15.2 0.0 0.047 13.8 0.0 1.7 1 1 0 1 1 1 0 Adenylate kinase Rad17 PF03215.15 AMK78977.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 AMK78977.1 - 0.052 14.1 0.0 0.089 13.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PTS-HPr PF00381.19 AMK78977.1 - 0.13 12.6 0.2 0.89 9.8 0.1 2.1 2 0 0 2 2 2 0 PTS HPr component phosphorylation site APS_kinase PF01583.20 AMK78977.1 - 0.18 11.7 0.8 2.8 7.8 0.1 2.4 2 1 0 2 2 2 0 Adenylylsulphate kinase S1 PF00575.23 AMK78978.1 - 8.8e-92 301.5 27.1 7.1e-22 77.5 0.1 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 AMK78978.1 - 1.6e-08 35.3 1.2 1.1 10.0 0.1 5.3 2 1 2 5 5 5 3 Penicillin-binding protein OB-like domain S1_2 PF13509.6 AMK78978.1 - 0.00014 21.9 11.1 5 7.3 0.0 6.7 6 4 0 6 6 6 3 S1 domain CsrA PF02599.16 AMK78978.1 - 0.0011 18.9 6.7 0.56 10.2 0.0 4.6 5 0 0 5 5 5 2 Global regulator protein family RsgI_N PF12791.7 AMK78978.1 - 0.046 13.6 5.5 1.2 9.1 0.0 5.0 6 0 0 6 6 6 0 Anti-sigma factor N-terminus BPL_C PF02237.17 AMK78978.1 - 0.19 11.7 12.4 9.5 6.2 0.1 5.0 5 0 0 5 5 5 0 Biotin protein ligase C terminal domain DUF1344 PF07076.11 AMK78978.1 - 0.29 11.1 8.8 9.6 6.2 0.0 4.9 6 1 0 6 6 6 0 Protein of unknown function (DUF1344) AXE1 PF05448.12 AMK78979.1 - 4.7e-30 104.4 0.0 5.9e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 AMK78979.1 - 0.14 11.6 0.3 0.32 10.4 0.3 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 AMK78980.1 - 1e-08 35.2 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AMK78980.1 - 0.00019 20.9 0.1 0.00039 20.0 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 AMK78980.1 - 0.011 15.0 0.0 0.041 13.2 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AMK78980.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 AMK78980.1 - 0.026 14.2 0.2 0.38 10.4 0.1 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 AMK78980.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) HlyD_D23 PF16576.5 AMK78981.1 - 6.7e-31 107.2 0.3 1.4e-30 106.1 0.3 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK78981.1 - 6.2e-18 65.4 3.4 7.6e-15 55.5 0.1 2.9 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK78981.1 - 9.1e-10 38.2 0.8 9.1e-10 38.2 0.8 2.9 4 0 0 4 4 4 1 Biotin-lipoyl like HlyD PF00529.20 AMK78981.1 - 3.6e-07 30.0 7.6 0.00037 20.3 7.6 2.5 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 AMK78981.1 - 0.00079 19.2 0.4 0.0055 16.5 0.1 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AMK78981.1 - 0.12 12.1 0.5 0.79 9.5 0.0 2.6 4 0 0 4 4 4 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ACR_tran PF00873.19 AMK78982.1 - 1.2e-259 864.1 20.3 1.4e-259 863.9 20.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK78982.1 - 9.3e-11 41.2 40.9 8.6e-07 28.2 16.8 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 AMK78982.1 - 0.00024 20.5 10.4 0.00024 20.5 10.4 2.7 3 0 0 3 3 3 2 Protein export membrane protein Peptidase_M41 PF01434.18 AMK78983.1 - 6.1e-65 218.7 0.0 9.6e-65 218.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AMK78983.1 - 3.7e-45 153.6 0.0 6.4e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AMK78983.1 - 3e-13 49.3 0.0 1.5e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 AMK78983.1 - 8.1e-08 32.6 0.1 2.7e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 AMK78983.1 - 4.5e-06 26.7 0.2 3.5e-05 23.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AMK78983.1 - 1.1e-05 24.9 0.1 2.3e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 AMK78983.1 - 0.00016 21.4 0.0 0.00069 19.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AMK78983.1 - 0.0011 19.4 3.4 0.031 14.6 0.2 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 AMK78983.1 - 0.0021 18.2 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AMK78983.1 - 0.005 17.1 0.1 0.3 11.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 AMK78983.1 - 0.0063 15.9 0.3 0.013 14.9 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 AMK78983.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 AMK78983.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 AMK78983.1 - 0.025 14.1 0.4 0.66 9.5 0.2 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 AMK78983.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AMK78983.1 - 0.086 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AMK78983.1 - 0.1 12.0 0.8 0.3 10.5 0.4 1.9 2 0 0 2 2 2 0 PhoH-like protein LPAM_1 PF08139.12 AMK78983.1 - 3 8.5 4.5 6.5 7.4 2.6 2.3 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site ATP-grasp PF02222.22 AMK78984.1 - 1.7e-51 174.2 0.0 2.5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 AMK78984.1 - 1.7e-15 56.4 0.0 3.8e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 AMK78984.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 AMK78984.1 - 0.0028 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 2-Hacid_dh_C PF02826.19 AMK78984.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.6 AMK78984.1 - 0.051 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain AIRC PF00731.20 AMK78985.1 - 8.2e-65 216.9 1.2 9.2e-65 216.7 1.2 1.0 1 0 0 1 1 1 1 AIR carboxylase DUF4781 PF16013.5 AMK78985.1 - 0.08 11.7 0.4 0.1 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RraB PF06877.11 AMK78985.1 - 0.13 13.0 0.0 0.2 12.4 0.0 1.2 1 0 0 1 1 1 0 Regulator of ribonuclease activity B ABC_tran PF00005.27 AMK78986.1 - 5.3e-27 95.0 0.0 7.8e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK78986.1 - 0.00067 19.6 0.6 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK78986.1 - 0.0017 17.9 0.1 1.1 8.6 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AMK78986.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AMK78986.1 - 0.013 15.9 0.4 0.019 15.3 0.4 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 AMK78986.1 - 0.013 16.0 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AMK78986.1 - 0.021 14.7 0.1 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF3584 PF12128.8 AMK78986.1 - 0.025 12.1 0.1 0.033 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GvpD PF07088.11 AMK78986.1 - 0.044 12.4 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_15 PF13175.6 AMK78986.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 AMK78986.1 - 0.1 11.2 0.0 0.81 8.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 AMK78986.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CcmB PF03379.13 AMK78987.1 - 7.8e-80 267.4 29.9 8.9e-80 267.2 29.9 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 AMK78987.1 - 1.7e-07 30.9 12.1 1.7e-07 30.9 12.1 1.5 1 1 1 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AMK78987.1 - 0.12 11.6 21.1 0.011 15.1 14.5 2.2 1 1 2 3 3 3 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AMK78987.1 - 2.7 7.0 20.1 0.99 8.4 15.8 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Cytochrom_C_asm PF01578.20 AMK78988.1 - 1.6e-30 106.5 18.3 1.6e-30 106.5 18.3 1.8 2 0 0 2 2 2 1 Cytochrome C assembly protein FSAP_sig_propep PF03032.15 AMK78988.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide DUF2070 PF09843.9 AMK78988.1 - 5.6 5.1 9.5 6.8 4.9 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CcmD PF04995.14 AMK78989.1 - 9e-19 67.3 0.9 1e-18 67.1 0.9 1.1 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) CcmE PF03100.15 AMK78990.1 - 1.5e-44 151.1 0.0 1.7e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 CcmE CcmF_C PF16327.5 AMK78991.1 - 2.6e-127 424.6 8.5 2.6e-127 424.6 8.5 1.8 2 0 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 AMK78991.1 - 1.1e-55 188.7 17.7 1.1e-55 188.7 17.7 2.7 2 1 0 2 2 2 1 Cytochrome C assembly protein DUF2651 PF10852.8 AMK78991.1 - 7.5 7.3 7.9 0.73 10.5 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2651) DUF3188 PF11384.8 AMK78991.1 - 8.3 6.2 13.7 1.9 8.3 0.6 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF3188) Redoxin PF08534.10 AMK78992.1 - 1.6e-22 79.8 0.0 2.1e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 AMK78992.1 - 2e-17 63.2 0.0 2.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AMK78992.1 - 2.4e-09 37.4 0.0 3.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AMK78992.1 - 1.8e-05 24.7 0.1 0.00034 20.6 0.1 2.0 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AMK78992.1 - 0.00025 21.5 0.0 0.00036 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain CcmH PF03918.14 AMK78993.1 - 2.2e-54 182.6 0.5 2.6e-54 182.4 0.5 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein Holin_BhlA PF10960.8 AMK78993.1 - 4.1e-05 23.5 1.7 0.0022 17.9 0.5 2.8 3 0 0 3 3 3 1 BhlA holin family T2SSF PF00482.23 AMK78993.1 - 0.00094 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F TPR_16 PF13432.6 AMK78994.1 - 2.3e-08 34.5 3.2 0.00035 21.2 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 AMK78994.1 - 6.5e-08 32.1 2.1 0.0058 16.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 AMK78994.1 - 5.7e-05 22.5 0.5 5.7e-05 22.5 0.5 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AMK78994.1 - 7.6e-05 23.2 15.4 0.0093 16.7 0.1 5.6 3 3 2 5 5 5 3 Tetratricopeptide repeat GvpG PF05120.12 AMK78994.1 - 0.00021 21.2 1.6 0.00021 21.2 1.6 2.0 2 0 0 2 2 2 1 Gas vesicle protein G TPR_19 PF14559.6 AMK78994.1 - 0.00025 21.5 1.9 0.034 14.6 0.3 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 AMK78994.1 - 0.00079 19.9 0.6 1.3 9.8 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat SHOCT PF09851.9 AMK78994.1 - 0.005 16.5 1.4 0.014 15.1 1.4 1.8 1 0 0 1 1 1 1 Short C-terminal domain TPR_9 PF13371.6 AMK78994.1 - 0.0051 16.9 1.2 0.29 11.3 0.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 AMK78994.1 - 0.014 15.8 8.7 0.066 13.6 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 AMK78994.1 - 0.033 13.9 0.7 2.6 7.8 0.0 3.3 2 1 1 3 3 3 0 TPR repeat TPR_17 PF13431.6 AMK78994.1 - 0.052 13.9 0.9 31 5.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 AMK78994.1 - 0.1 11.7 2.3 4.3 6.4 0.1 2.4 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 AMK78994.1 - 0.15 12.1 1.3 3 8.1 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 AMK78994.1 - 0.18 11.6 0.8 17 5.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Radical_SAM PF04055.21 AMK78995.1 - 5.4e-18 65.9 0.0 1.6e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.16 AMK78995.1 - 9.2e-13 48.1 0.6 2.6e-12 46.6 0.2 2.1 2 0 0 2 2 2 1 HemN C-terminal domain Transposase_mut PF00872.18 AMK78996.1 - 1.5e-120 402.6 0.0 1.8e-120 402.3 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 AMK78996.1 - 1.6e-05 25.2 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 AMK78996.1 - 0.015 15.0 0.0 0.84 9.3 0.0 2.1 1 1 1 2 2 2 0 Transposase CstA PF02554.14 AMK78997.1 - 1.3e-164 547.6 21.3 1.3e-164 547.6 21.3 1.8 2 0 0 2 2 2 1 Carbon starvation protein CstA CstA_5TM PF13722.6 AMK78997.1 - 1.7e-36 125.1 7.6 1.7e-36 125.1 7.6 2.9 2 0 0 2 2 2 1 5TM C-terminal transporter carbon starvation CstA DUF3278 PF11683.8 AMK78997.1 - 0.15 12.1 3.0 0.27 11.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Cytochrome_P460 PF16694.5 AMK78998.1 - 5.5e-35 120.4 0.1 6.6e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P460 Hist_deacetyl PF00850.19 AMK78999.1 - 1.2e-80 271.3 0.0 1.6e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MerB PF03243.15 AMK78999.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Alkylmercury lyase PAC2 PF09754.9 AMK78999.1 - 0.087 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 PAC2 family GTP_EFTU PF00009.27 AMK79000.1 - 7e-49 166.0 0.0 1e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 AMK79000.1 - 1.8e-43 147.5 0.0 3.6e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 AMK79000.1 - 8e-09 35.8 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AMK79000.1 - 6.7e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AMK79000.1 - 0.0034 17.4 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 AMK79000.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Ras family SRPRB PF09439.10 AMK79000.1 - 0.18 11.2 0.1 0.85 9.0 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ni_hydr_CYTB PF01292.20 AMK79001.1 - 3.5e-30 105.0 7.4 3.9e-30 104.8 7.4 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 AMK79001.1 - 0.049 13.8 3.8 0.77 9.9 1.0 2.8 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 DUF3365 PF11845.8 AMK79002.1 - 4.8e-32 111.5 0.0 1.1e-31 110.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) HATPase_c PF02518.26 AMK79002.1 - 1.3e-20 73.9 0.4 3.6e-20 72.5 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK79002.1 - 1.7e-05 24.8 1.8 1.7e-05 24.8 1.8 2.6 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AMK79002.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AMK79002.1 - 0.069 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain MerR-DNA-bind PF09278.11 AMK79002.1 - 0.56 10.8 3.1 0.9 10.1 1.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF3369 PF11849.8 AMK79003.1 - 4.3e-21 75.8 0.2 9.2e-21 74.8 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3369) HD_5 PF13487.6 AMK79003.1 - 8.4e-17 61.2 0.2 1.4e-15 57.3 0.1 2.6 2 0 0 2 2 2 1 HD domain HD PF01966.22 AMK79003.1 - 3.5e-13 49.9 0.2 7.2e-13 48.8 0.2 1.6 1 0 0 1 1 1 1 HD domain Response_reg PF00072.24 AMK79003.1 - 1.9e-05 24.8 0.5 4.7e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain GAF_3 PF13492.6 AMK79003.1 - 0.083 13.2 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 GAF domain Lipocalin_4 PF13648.6 AMK79005.1 - 4.9e-05 24.2 0.3 6.1e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 Lipocalin-like domain GH43_C PF16369.5 AMK79005.1 - 0.0015 19.1 0.1 0.0017 18.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal lipocalin-like domain DUF5640 PF18692.1 AMK79005.1 - 0.0032 17.5 1.3 0.0057 16.7 1.3 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5640) DUF3598 PF12204.8 AMK79005.1 - 0.018 14.5 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) DUF455 PF04305.14 AMK79006.1 - 9.9e-88 293.8 0.0 1.1e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) NnrS PF05940.12 AMK79007.1 - 1.6e-104 350.2 65.0 1.8e-104 350.0 65.0 1.0 1 0 0 1 1 1 1 NnrS protein GcpE PF04551.14 AMK79008.1 - 1.5e-113 379.5 0.2 1.7e-113 379.3 0.2 1.0 1 0 0 1 1 1 1 GcpE protein Turandot PF07240.11 AMK79008.1 - 0.09 12.8 0.0 0.42 10.6 0.0 2.1 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Metallophos PF00149.28 AMK79009.1 - 6.6e-12 46.4 0.4 1e-11 45.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AMK79009.1 - 6.5e-10 39.4 0.0 2e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NQRA PF05896.11 AMK79010.1 - 1.2e-107 359.1 0.1 1.3e-105 352.5 0.0 2.0 2 0 0 2 2 2 2 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NQRA_SLBB PF11973.8 AMK79010.1 - 4e-21 75.4 0.3 9.7e-21 74.2 0.3 1.7 1 0 0 1 1 1 1 NQRA C-terminal domain RnfC_N PF13375.6 AMK79010.1 - 0.00099 19.0 0.0 0.0057 16.6 0.0 2.3 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain SLBB PF10531.9 AMK79010.1 - 0.018 14.9 0.2 0.044 13.6 0.2 1.7 1 0 0 1 1 1 0 SLBB domain NQR2_RnfD_RnfE PF03116.15 AMK79011.1 - 1.1e-103 346.7 23.6 1.3e-103 346.5 23.6 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family FMN_bind PF04205.14 AMK79012.1 - 5.1e-14 52.6 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 FMN-binding domain Rnf-Nqr PF02508.14 AMK79013.1 - 8.8e-61 204.9 10.7 1e-60 204.7 10.7 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein Rnf-Nqr PF02508.14 AMK79014.1 - 3.1e-56 190.1 17.6 3.5e-56 189.9 17.6 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF2456 PF10445.9 AMK79014.1 - 0.082 13.0 3.0 1.5 8.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) NAD_binding_1 PF00175.21 AMK79015.1 - 4.2e-17 62.8 0.0 8.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 AMK79015.1 - 7e-11 41.9 0.2 1.2e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 AMK79015.1 - 1.7e-08 34.7 0.0 8.8e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 AMK79015.1 - 0.0014 18.7 0.0 0.034 14.3 0.0 2.5 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 AMK79015.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain NT-C2 PF10358.9 AMK79015.1 - 0.095 12.4 0.1 0.92 9.2 0.1 2.1 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins NqrM PF04400.13 AMK79016.1 - 6.5e-06 25.8 11.6 4.1e-05 23.2 11.6 1.9 1 1 0 1 1 1 1 (Na+)-NQR maturation NqrM FeoB_associated PF12669.7 AMK79016.1 - 0.044 14.2 4.3 0.064 13.7 4.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein 2OG-FeII_Oxy_2 PF13532.6 AMK79017.1 - 5e-31 108.4 0.0 5.7e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hemerythrin PF01814.23 AMK79018.1 - 4.8e-07 30.5 0.1 5.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2529 PF10740.9 AMK79018.1 - 0.036 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Exonuc_VII_L PF02601.15 AMK79019.1 - 6.5e-102 341.2 5.9 9.8e-102 340.6 5.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 AMK79019.1 - 7e-30 103.1 0.3 2.3e-29 101.4 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 AMK79019.1 - 3.7e-08 33.2 0.0 6.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FUSC PF04632.12 AMK79019.1 - 0.15 10.6 14.9 0.21 10.1 14.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cation_efflux PF01545.21 AMK79020.1 - 1.4e-38 132.6 3.8 1.9e-38 132.2 3.8 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 AMK79020.1 - 6.2e-08 32.2 6.2 1.1e-07 31.4 6.2 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.16 AMK79020.1 - 0.0002 20.8 10.3 0.0002 20.8 10.3 1.8 1 1 0 2 2 2 1 High-affinity nickel-transport protein V_ATPase_I PF01496.19 AMK79020.1 - 0.0013 16.7 0.1 0.0016 16.4 0.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Trp_oprn_chp PF09534.10 AMK79020.1 - 0.0032 17.3 3.5 0.026 14.3 1.3 2.4 1 1 1 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ctr PF04145.15 AMK79020.1 - 0.035 14.7 0.0 0.064 13.9 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF4027 PF13219.6 AMK79020.1 - 0.15 12.0 2.4 0.38 10.6 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DNA_pol_phi PF04931.13 AMK79020.1 - 0.18 9.9 1.7 0.25 9.4 1.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4342 PF14242.6 AMK79020.1 - 0.2 11.6 0.3 0.2 11.6 0.3 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4342) UPF0016 PF01169.19 AMK79020.1 - 0.44 10.9 11.1 1.8 9.0 1.5 2.9 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 DUF3040 PF11239.8 AMK79020.1 - 1.2 9.5 7.8 12 6.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) FAM176 PF14851.6 AMK79020.1 - 1.2 8.8 6.8 0.12 12.0 1.7 2.0 2 1 1 3 3 3 0 FAM176 family DUF4956 PF16316.5 AMK79020.1 - 4.3 7.0 7.2 0.95 9.1 3.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4956) Methyltransf_23 PF13489.6 AMK79021.1 - 4.9e-22 78.5 0.0 7.5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK79021.1 - 5.1e-06 26.4 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 AMK79021.1 - 9.4e-06 26.3 0.0 5.4e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK79021.1 - 3.9e-05 24.2 0.1 0.0033 18.0 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK79021.1 - 0.00017 22.2 0.0 0.18 12.5 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Lar_restr_allev PF14354.6 AMK79021.1 - 0.036 14.5 0.1 0.082 13.3 0.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF2387 PF09526.10 AMK79021.1 - 0.1 12.8 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-piccolo PF05715.13 AMK79021.1 - 0.4 10.9 3.0 0.3 11.2 1.2 1.7 2 0 0 2 2 2 0 Piccolo Zn-finger Zn_Tnp_IS1 PF03811.13 AMK79021.1 - 9.5 6.0 9.5 1.1 9.0 4.7 2.0 2 0 0 2 2 2 0 InsA N-terminal domain NUDIX PF00293.28 AMK79022.1 - 7.1e-20 71.4 0.0 8.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TetR_C_33 PF13305.6 AMK79023.1 - 3.4e-10 40.6 0.0 5.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AMK79023.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family MFS_1 PF07690.16 AMK79024.1 - 1.6e-14 53.6 43.3 1.6e-14 53.6 43.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Cohesin PF00963.18 AMK79025.1 - 3.7e-08 33.7 0.9 5.6e-08 33.1 0.9 1.3 1 0 0 1 1 1 1 Cohesin domain He_PIG PF05345.12 AMK79026.1 - 5.2e-06 26.5 2.8 5.2e-06 26.5 2.8 2.0 2 0 0 2 2 2 1 Putative Ig domain Dockerin_1 PF00404.18 AMK79026.1 - 0.47 10.7 7.7 2.2 8.6 7.7 2.2 1 1 0 1 1 1 0 Dockerin type I domain DUF4096 PF13340.6 AMK79027.1 - 9.2e-25 86.7 2.8 1.9e-24 85.7 2.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK79028.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK79028.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK79028.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK79028.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease BNR_4 PF15892.5 AMK79030.1 - 0.012 15.0 0.9 0.13 11.6 0.0 2.6 1 1 1 2 2 2 0 BNR repeat-containing family member DUF4871 PF16167.5 AMK79030.1 - 0.96 9.5 3.8 0.64 10.0 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4871) FG-GAP PF01839.23 AMK79031.1 - 1.8e-48 162.2 73.0 1.3e-10 41.2 3.1 8.5 8 0 0 8 8 8 7 FG-GAP repeat VCBS PF13517.6 AMK79031.1 - 3e-21 75.8 69.1 3e-07 30.9 3.9 6.3 3 1 4 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 AMK79031.1 - 3.1e-05 23.4 18.9 1.6 8.1 0.2 6.9 6 1 1 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Ni_hydr_CYTB PF01292.20 AMK79032.1 - 2.2e-25 89.3 3.9 4.5e-25 88.3 3.9 1.5 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AMK79032.1 - 5e-07 30.2 3.7 1.4e-05 25.5 0.0 2.9 2 2 0 2 2 2 1 Domain of unknown function (DUF4405) DUF4079 PF13301.6 AMK79032.1 - 0.12 12.5 3.6 3.8 7.7 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) SPC12 PF06645.13 AMK79032.1 - 4.5 7.4 7.2 0.33 11.1 1.3 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Response_reg PF00072.24 AMK79033.1 - 5.2e-24 84.6 0.0 7.2e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AMK79033.1 - 6.9e-22 77.3 0.1 1.2e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal VD10_N PF08476.10 AMK79033.1 - 0.036 13.7 0.2 0.77 9.5 0.0 2.3 2 0 0 2 2 2 0 Viral D10 N-terminal HATPase_c PF02518.26 AMK79034.1 - 4.7e-11 43.2 0.0 1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AMK79034.1 - 1.9e-05 24.5 0.0 5.8e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AMK79034.1 - 0.012 15.6 0.3 0.043 13.8 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HisKA PF00512.25 AMK79034.1 - 0.051 13.6 3.6 0.088 12.9 0.7 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DotU PF09850.9 AMK79034.1 - 0.38 10.4 3.4 0.16 11.7 0.5 1.8 2 0 0 2 2 2 0 Type VI secretion system protein DotU DUF4381 PF14316.6 AMK79034.1 - 1.8 8.8 7.2 0.14 12.4 0.7 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) Lyase_1 PF00206.20 AMK79035.1 - 8.6e-79 265.2 0.0 1.3e-78 264.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AMK79035.1 - 2.4e-25 89.1 0.2 6.6e-25 87.7 0.2 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal TPR_14 PF13428.6 AMK79036.1 - 0.0045 17.7 1.9 0.064 14.1 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat NA37 PF04245.13 AMK79036.1 - 0.025 14.1 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Dabb PF07876.12 AMK79036.1 - 0.086 13.5 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain ATP_bind_1 PF03029.17 AMK79038.1 - 6.6e-11 42.4 0.3 2.1e-07 31.0 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 AMK79038.1 - 1.8e-06 27.7 0.0 0.014 15.1 0.0 2.4 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 AMK79038.1 - 1.5e-05 25.0 0.0 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Ras PF00071.22 AMK79038.1 - 2.6e-05 23.9 0.0 4.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 AMK79038.1 - 6.4e-05 23.0 0.2 7.3e-05 22.8 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 AMK79038.1 - 0.00042 20.5 0.0 0.00075 19.7 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 AMK79038.1 - 0.0094 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AMK79038.1 - 0.012 15.8 0.0 0.092 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AMK79038.1 - 0.016 15.7 0.1 0.025 15.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AMK79038.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 AMK79038.1 - 0.025 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AMK79038.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 AMK79038.1 - 0.04 14.5 0.0 0.081 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AMK79038.1 - 0.05 13.0 0.1 0.13 11.6 0.0 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 AMK79038.1 - 0.061 13.2 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 AMK79038.1 - 0.065 13.7 0.1 0.16 12.5 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 AMK79038.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 AMK79038.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AMK79038.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain LAMTOR5 PF16672.5 AMK79039.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 AMK79040.1 - 2.2e-16 59.4 1.3 2.7e-16 59.1 1.3 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain PAS_3 PF08447.12 AMK79041.1 - 6.1e-15 55.3 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AMK79041.1 - 1.1e-11 44.9 0.0 2.3e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AMK79041.1 - 1.3e-11 44.5 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 AMK79041.1 - 5.7e-08 33.0 0.0 7.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 AMK79041.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 PAS domain Phosphonate-bd PF12974.7 AMK79042.1 - 2.2e-31 109.3 0.0 2.5e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 AMK79042.1 - 0.0073 15.8 0.3 0.14 11.6 0.1 2.0 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 AMK79042.1 - 0.0079 16.2 0.1 0.034 14.1 0.1 1.8 1 1 1 2 2 2 1 NMT1/THI5 like Sm_like PF16243.5 AMK79042.1 - 0.044 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Sm_like domain His_Phos_1 PF00300.22 AMK79043.1 - 4.9e-42 143.8 0.0 5.6e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Adenylate_cycl PF01295.18 AMK79044.1 - 4.4e-109 365.8 0.1 5.5e-109 365.5 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase, class-I Adenyl_cycl_N PF12633.7 AMK79044.1 - 4.7e-69 232.3 0.0 8e-69 231.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase NT domain Polbeta PF18765.1 AMK79044.1 - 0.00061 19.8 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TonB_dep_Rec PF00593.24 AMK79046.1 - 2.2e-25 90.5 25.0 2.8e-25 90.2 23.2 1.7 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK79046.1 - 7.9e-21 74.6 0.0 1.9e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 AMK79046.1 - 1.9e-07 30.4 6.3 4.4e-06 25.9 1.2 2.6 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family DUF4154 PF13689.6 AMK79047.1 - 2.6e-38 131.5 0.1 3.1e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 YfiR/HmsC-like Ribosomal_L31 PF01197.18 AMK79047.1 - 0.19 12.0 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31 EAL PF00563.20 AMK79048.1 - 1.1e-69 234.6 1.2 1.3e-67 227.8 0.0 2.7 2 0 0 2 2 2 1 EAL domain Response_reg PF00072.24 AMK79048.1 - 8e-68 225.7 4.0 3.5e-25 88.4 0.3 4.1 3 0 0 3 3 3 3 Response regulator receiver domain GGDEF PF00990.21 AMK79048.1 - 8.8e-49 165.4 0.2 2.4e-48 163.9 0.2 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HATPase_c PF02518.26 AMK79048.1 - 3.5e-28 98.3 0.5 1.2e-27 96.6 0.2 2.2 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AMK79048.1 - 2e-20 72.6 0.2 3.8e-19 68.5 0.1 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CHASE8 PF17152.4 AMK79048.1 - 1.4e-17 63.8 0.1 1.4e-16 60.6 0.1 2.7 1 1 0 1 1 1 1 Periplasmic sensor domain Hpt PF01627.23 AMK79048.1 - 3.7e-10 39.9 2.7 3.7e-10 39.9 2.7 2.7 3 0 0 3 3 2 1 Hpt domain HAMP PF00672.25 AMK79048.1 - 1.8e-07 31.4 0.0 2.5e-06 27.7 0.0 2.7 2 0 0 2 2 2 1 HAMP domain SMP_2 PF10144.9 AMK79048.1 - 0.0094 15.6 1.2 0.079 12.6 0.8 2.6 2 0 0 2 2 2 1 Bacterial virulence factor haemolysin PUB_1 PF18486.1 AMK79048.1 - 0.081 12.8 0.3 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain PAS_3 PF08447.12 AMK79048.1 - 0.13 12.6 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold HDOD PF08668.12 AMK79049.1 - 3.4e-38 131.1 0.2 8.9e-38 129.7 0.1 1.6 2 0 0 2 2 2 1 HDOD domain PepSY_TM PF03929.16 AMK79050.1 - 3.6e-56 191.0 11.4 4.6e-56 190.6 11.4 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 AMK79050.1 - 0.1 13.2 0.0 49 4.6 0.0 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Competence PF03772.16 AMK79051.1 - 1.2e-64 218.3 45.0 1.2e-64 218.3 45.0 1.6 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 AMK79051.1 - 6.9e-26 90.9 0.4 6.9e-26 90.9 0.4 5.8 3 1 3 6 6 6 1 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 AMK79051.1 - 2.4e-14 53.8 0.0 4.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK79051.1 - 0.035 13.6 0.0 0.087 12.3 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PilZ PF07238.14 AMK79052.1 - 1.2e-05 25.6 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 PilZ domain DEAD PF00270.29 AMK79053.1 - 2.1e-50 170.9 0.1 7.2e-50 169.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK79053.1 - 1.7e-31 108.8 0.2 5.9e-29 100.7 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DbpA PF03880.15 AMK79053.1 - 3.2e-23 81.5 0.4 1e-22 79.9 0.1 2.1 2 0 0 2 2 2 1 DbpA RNA binding domain ResIII PF04851.15 AMK79053.1 - 2.1e-06 27.8 0.1 5.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AMK79053.1 - 7.5e-05 23.1 0.2 0.00038 20.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 AMK79053.1 - 0.00055 19.4 0.1 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 AMK79053.1 - 0.007 16.1 0.1 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 AMK79053.1 - 0.0072 15.2 0.1 1.1 8.0 0.1 2.9 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 EST1 PF10374.9 AMK79053.1 - 0.089 13.4 0.1 0.22 12.1 0.1 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 COX15-CtaA PF02628.15 AMK79054.1 - 1.5e-53 182.0 17.0 2.1e-53 181.5 17.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1516 PF07457.11 AMK79054.1 - 0.31 11.3 0.2 0.31 11.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) DUF2231 PF09990.9 AMK79054.1 - 0.72 10.3 16.5 0.25 11.8 2.1 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) HDOD PF08668.12 AMK79055.1 - 3e-42 144.3 0.3 5.1e-42 143.6 0.3 1.3 1 1 0 1 1 1 1 HDOD domain GCV_T PF01571.21 AMK79056.1 - 5.5e-11 42.3 0.0 8.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain HDOD PF08668.12 AMK79058.1 - 1e-40 139.3 0.0 1.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 HDOD domain HTH_24 PF13412.6 AMK79058.1 - 0.15 11.7 0.5 0.61 9.7 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding GGDEF PF00990.21 AMK79059.1 - 1.6e-44 151.5 0.3 3.2e-44 150.5 0.3 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF_2 PF13185.6 AMK79059.1 - 8.6e-13 48.8 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 AMK79059.1 - 2.1e-07 31.7 0.0 3.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GGDEF_2 PF17853.1 AMK79059.1 - 0.014 15.6 0.0 0.06 13.6 0.0 2.0 2 0 0 2 2 2 0 GGDEF-like domain BORCS8 PF10167.9 AMK79059.1 - 0.028 14.3 0.3 2 8.4 0.1 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 YchF-GTPase_C PF06071.13 AMK79060.1 - 3.3e-40 136.2 0.5 8.8e-40 134.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AMK79060.1 - 1.7e-23 82.8 0.0 7.5e-23 80.8 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AMK79060.1 - 3.4e-08 33.2 0.8 2e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 AMK79060.1 - 0.025 13.6 0.3 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TGS PF02824.21 AMK79060.1 - 0.045 13.8 0.5 0.34 11.0 0.1 2.5 2 1 0 2 2 2 0 TGS domain Dynamin_N PF00350.23 AMK79060.1 - 0.045 13.8 0.2 1.4 9.0 0.2 2.9 1 1 0 1 1 1 0 Dynamin family O_anti_polymase PF01901.16 AMK79061.1 - 0.0041 16.4 0.7 0.0044 16.3 0.7 1.0 1 0 0 1 1 1 1 Putative O-antigen polymerase NERD PF08378.11 AMK79062.1 - 0.0019 18.7 0.0 0.0055 17.2 0.0 1.8 1 0 0 1 1 1 1 Nuclease-related domain PSII_BNR PF14870.6 AMK79063.1 - 7e-48 163.4 48.9 2.4e-13 50.0 1.9 5.5 1 1 5 6 6 6 6 Photosynthesis system II assembly factor YCF48 KAP_NTPase PF07693.14 AMK79063.1 - 3.2e-24 85.8 0.0 1.5e-11 44.1 0.0 3.2 2 1 0 2 2 2 2 KAP family P-loop domain Sortilin-Vps10 PF15902.5 AMK79063.1 - 2.6e-07 29.8 2.5 0.012 14.4 0.1 3.4 1 1 2 3 3 3 3 Sortilin, neurotensin receptor 3, AAA_16 PF13191.6 AMK79063.1 - 5.7e-05 23.6 0.6 0.41 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain BNR PF02012.20 AMK79063.1 - 0.00016 21.2 8.4 21 5.6 0.2 7.2 7 0 0 7 7 7 0 BNR/Asp-box repeat AAA_22 PF13401.6 AMK79063.1 - 0.0025 18.1 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 AMK79063.1 - 0.035 14.0 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 AMK79063.1 - 0.061 12.8 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 AMK79063.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase Cytomega_UL20A PF05984.12 AMK79063.1 - 0.64 10.4 11.4 80 3.6 0.1 5.7 1 1 5 6 6 6 0 Cytomegalovirus UL20A protein SIR2_2 PF13289.6 AMK79064.1 - 5e-25 88.3 0.0 9.7e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 SIR2-like domain SIR2 PF02146.17 AMK79064.1 - 0.1 12.5 0.1 5.7 6.8 0.0 2.5 1 1 1 2 2 2 0 Sir2 family Caveolin PF01146.17 AMK79064.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Caveolin Methylase_S PF01420.19 AMK79065.1 - 1.7e-27 96.7 0.0 4.4e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain Bac_rhamnosid6H PF17389.2 AMK79065.1 - 0.023 13.9 0.3 0.023 13.9 0.3 1.7 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain N6_Mtase PF02384.16 AMK79066.1 - 1.5e-79 267.5 0.0 2e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AMK79066.1 - 1.9e-15 57.7 0.1 5.2e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 HsdM N-terminal domain MTS PF05175.14 AMK79066.1 - 2.8e-06 27.0 0.2 0.0046 16.5 0.0 3.7 3 1 0 3 3 3 1 Methyltransferase small domain UPF0020 PF01170.18 AMK79066.1 - 7.2e-05 22.5 0.1 0.00021 21.0 0.1 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Eco57I PF07669.11 AMK79066.1 - 0.0018 18.8 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 Eco57I restriction-modification methylase ResIII PF04851.15 AMK79067.1 - 1.7e-43 148.6 0.1 5.5e-43 146.9 0.1 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EcoEI_R_C PF08463.10 AMK79067.1 - 6.1e-30 104.5 3.7 6.4e-30 104.5 2.0 1.9 2 0 0 2 2 2 1 EcoEI R protein C-terminal SWI2_SNF2 PF18766.1 AMK79067.1 - 2e-18 66.9 0.1 4.9e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 AMK79067.1 - 8.4e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSDR_N PF04313.14 AMK79067.1 - 6.4e-06 26.3 0.0 0.0002 21.4 0.0 2.5 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N_2 PF13588.6 AMK79067.1 - 2.4e-05 24.3 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Helicase_C PF00271.31 AMK79067.1 - 0.00054 20.3 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 AMK79067.1 - 0.0096 16.3 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 AMK79067.1 - 0.01 15.3 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 AMK79067.1 - 0.027 14.3 0.2 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AMK79067.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 AMK79067.1 - 0.11 12.0 1.2 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 AMK79067.1 - 0.14 12.2 1.0 0.71 9.9 0.0 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain SNF2_N PF00176.23 AMK79067.1 - 0.18 10.5 0.0 0.81 8.3 0.0 1.7 1 1 1 2 2 2 0 SNF2 family N-terminal domain DUF927 PF06048.11 AMK79068.1 - 0.00027 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF927) CW_binding_1 PF01473.20 AMK79068.1 - 0.091 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat RNase_II_C_S1 PF18614.1 AMK79068.1 - 0.12 12.4 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Toprim_3 PF13362.6 AMK79069.1 - 5.5e-11 42.7 0.0 1.8e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 AMK79069.1 - 2.7e-06 27.7 0.0 1.4e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Toprim domain Cas_Cas02710 PF09670.10 AMK79072.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Phage_integrase PF00589.22 AMK79073.1 - 2.8e-24 85.8 0.6 1.6e-22 80.1 0.0 2.9 2 1 0 2 2 2 1 Phage integrase family Phage_int_SAM_5 PF13102.6 AMK79073.1 - 0.0025 18.1 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase SAM-like domain HTH_32 PF13565.6 AMK79073.1 - 0.62 10.7 3.5 9.4 6.9 0.0 3.2 4 0 0 4 4 4 0 Homeodomain-like domain Trp_halogenase PF04820.14 AMK79075.1 - 1.4e-39 136.2 0.5 2.3e-24 86.1 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 AMK79075.1 - 6.1e-18 65.2 0.0 8.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AMK79075.1 - 1.8e-08 34.2 0.2 5.8e-08 32.5 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AMK79075.1 - 7e-08 32.0 0.1 3.3e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AMK79075.1 - 2.1e-06 27.2 0.0 1.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AMK79075.1 - 3.6e-06 26.0 0.1 2.6e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 AMK79075.1 - 6.4e-06 26.3 0.3 1.8e-05 24.9 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK79075.1 - 9.7e-06 25.4 0.2 7.3e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 AMK79075.1 - 4.6e-05 22.7 0.1 6.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 AMK79075.1 - 0.00025 20.4 0.0 0.0034 16.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 AMK79075.1 - 0.00029 21.3 0.0 0.00088 19.8 0.1 1.9 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 AMK79075.1 - 0.00046 19.3 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 AMK79075.1 - 0.009 15.3 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AMK79075.1 - 0.097 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Na_H_Exchanger PF00999.21 AMK79076.1 - 2.6e-26 92.3 36.8 1.1e-25 90.2 36.8 1.8 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Amino_oxidase PF01593.24 AMK79077.1 - 5.2e-20 72.2 0.0 9.2e-20 71.3 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AMK79077.1 - 8e-13 48.4 2.2 8e-13 48.4 2.2 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK79077.1 - 8.3e-11 42.1 7.8 8.5e-10 38.7 7.2 2.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 AMK79077.1 - 7.7e-07 28.8 0.1 8e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 AMK79077.1 - 1.1e-06 28.0 0.7 0.0052 15.9 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 AMK79077.1 - 2.2e-06 27.1 2.9 0.00013 21.3 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK79077.1 - 3.8e-06 26.2 2.9 1.2e-05 24.6 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 AMK79077.1 - 4.1e-06 26.3 0.0 4.1e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AMK79077.1 - 3.5e-05 23.1 0.5 0.002 17.2 0.2 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 AMK79077.1 - 6.5e-05 23.4 4.8 0.00012 22.5 0.2 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 AMK79077.1 - 7.2e-05 21.5 0.1 0.0085 14.6 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor HI0933_like PF03486.14 AMK79077.1 - 0.0001 21.1 0.3 0.0019 17.0 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 AMK79077.1 - 0.00013 21.3 0.1 0.00034 19.9 0.1 1.6 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 AMK79077.1 - 0.016 15.1 0.4 0.028 14.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 AMK79077.1 - 0.064 13.2 3.6 6.1 6.8 0.2 3.0 4 0 0 4 4 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 AMK79077.1 - 0.076 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 AMK79077.1 - 0.081 12.6 0.3 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DDE_Tnp_1_2 PF13586.6 AMK79078.1 - 1.3e-14 54.3 0.2 1.6e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK79078.1 - 6.2e-13 48.9 2.3 2.3e-11 43.7 2.3 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK79078.1 - 1.3e-06 28.5 0.0 1.6e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK79078.1 - 1.2e-05 25.1 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4096 PF13340.6 AMK79079.1 - 6.7e-24 83.9 4.8 1.4e-23 82.9 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) rve PF00665.26 AMK79080.1 - 1.7e-27 95.9 0.0 3.2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK79080.1 - 6.1e-12 45.1 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AMK79080.1 - 3.7e-07 30.2 0.5 6.3e-07 29.4 0.5 1.4 1 0 0 1 1 1 1 HTH-like domain Rhomboid_SP PF12595.8 AMK79080.1 - 0.045 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Rhomboid serine protease Lyase_1 PF00206.20 AMK79081.1 - 2.7e-105 352.2 0.0 3.6e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 AMK79081.1 - 1.2e-21 76.8 0.0 3e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus G-alpha PF00503.20 AMK79081.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Haem_degrading PF03928.14 AMK79082.1 - 6.9e-33 113.2 1.5 7.8e-33 113.1 1.5 1.0 1 0 0 1 1 1 1 Haem-degrading Lactamase_B PF00753.27 AMK79083.1 - 0.13 12.2 0.8 0.35 10.9 0.7 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Prim_Zn_Ribbon PF08273.12 AMK79083.1 - 0.15 12.4 0.9 7.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Rubredoxin PF00301.20 AMK79083.1 - 1.6 8.8 6.6 12 6.1 0.2 3.8 4 0 0 4 4 4 0 Rubredoxin DUF393 PF04134.12 AMK79084.1 - 1.2e-17 65.2 0.0 1.4e-17 65.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 GGDEF PF00990.21 AMK79086.1 - 2.8e-43 147.4 0.1 9.4e-43 145.7 0.1 2.0 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 AMK79086.1 - 6.4e-17 61.6 0.0 1.2e-13 51.2 0.0 2.7 2 1 0 2 2 2 2 PAS fold PAS PF00989.25 AMK79086.1 - 4.2e-15 55.7 0.0 2.3e-10 40.5 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AMK79086.1 - 3.8e-14 52.8 0.0 1.6e-09 37.9 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 AMK79086.1 - 5.6e-11 42.2 0.0 2.7e-09 36.8 0.0 2.8 2 0 0 2 2 2 1 PAS domain Response_reg PF00072.24 AMK79086.1 - 2.6e-08 34.0 0.1 5.9e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 AMK79086.1 - 6.8e-08 32.7 0.0 0.00027 21.2 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_7 PF12860.7 AMK79086.1 - 0.0029 17.7 0.0 0.009 16.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF3552 PF12072.8 AMK79086.1 - 0.72 9.2 5.2 1.7 8.0 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HTH_Tnp_1 PF01527.20 AMK79087.1 - 9.3e-14 51.5 0.1 1.1e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 AMK79087.1 - 1.7e-06 27.3 0.1 4e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AMK79087.1 - 0.00011 21.9 0.0 0.00041 20.1 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 AMK79087.1 - 0.00079 19.5 0.1 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AMK79087.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 LZ_Tnp_IS481 PF13011.6 AMK79087.1 - 0.038 14.5 0.0 0.073 13.6 0.0 1.5 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 Terminase_5 PF06056.12 AMK79087.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1_2 PF13022.6 AMK79087.1 - 0.059 13.5 0.0 0.064 13.4 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 AMK79087.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_18 PF12833.7 AMK79087.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GOLGA2L5 PF15070.6 AMK79087.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 VEK-30 PF12107.8 AMK79087.1 - 1.5 8.8 4.1 5 7.2 1.8 2.2 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway PRA-PH PF01503.17 AMK79089.1 - 0.043 14.3 0.1 0.21 12.0 0.0 2.1 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase zinc_ribbon_6 PF14599.6 AMK79089.1 - 0.065 13.2 0.6 7.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon PAS_3 PF08447.12 AMK79090.1 - 5.2e-69 228.6 10.9 3.1e-19 69.0 0.0 7.5 7 0 0 7 7 7 6 PAS fold PAS_4 PF08448.10 AMK79090.1 - 3.4e-44 149.6 7.4 7.8e-17 61.5 0.0 7.4 7 1 0 7 7 7 5 PAS fold PAS PF00989.25 AMK79090.1 - 8.9e-25 86.9 0.9 2.4e-06 27.5 0.0 7.6 7 1 0 7 7 7 5 PAS fold PAS_9 PF13426.7 AMK79090.1 - 5e-19 68.5 0.0 3.7e-05 23.9 0.0 6.8 7 0 0 7 7 7 3 PAS domain HATPase_c PF02518.26 AMK79090.1 - 3.8e-13 49.9 0.0 8.6e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AMK79090.1 - 1.4e-09 38.4 0.0 6e-07 30.0 0.0 3.9 5 0 0 5 5 4 1 PAS domain HisKA PF00512.25 AMK79090.1 - 2.9e-08 33.6 0.7 8.1e-08 32.2 0.7 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AMK79090.1 - 1.7e-07 31.1 0.8 0.28 11.3 0.0 4.8 4 0 0 4 4 4 2 PAS domain PAS_6 PF08348.11 AMK79090.1 - 0.0053 16.6 0.0 0.46 10.4 0.0 3.6 4 0 0 4 4 4 1 YheO-like PAS domain HATPase_c_5 PF14501.6 AMK79090.1 - 0.0087 15.9 0.4 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 GHKL domain VanY PF02557.17 AMK79090.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF4118 PF13493.6 AMK79090.1 - 0.35 10.7 4.4 0.18 11.6 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) Response_reg PF00072.24 AMK79091.1 - 2.7e-24 85.5 0.0 4.3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AMK79091.1 - 7.7e-19 67.0 0.1 1.2e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AMK79091.1 - 4.6e-07 29.4 0.1 9.5e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 AMK79091.1 - 2.3e-06 27.2 0.1 4.6e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 AMK79091.1 - 0.0006 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AMK79091.1 - 0.0013 18.2 0.5 0.0013 18.2 0.5 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 RP-C PF03428.13 AMK79091.1 - 0.0024 17.6 0.3 0.022 14.4 0.1 2.1 2 0 0 2 2 2 1 Replication protein C N-terminal domain HTH_38 PF13936.6 AMK79091.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK79091.1 - 0.02 14.9 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 AMK79091.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 AMK79091.1 - 0.032 13.8 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 AMK79091.1 - 0.032 14.3 0.1 0.075 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase KORA PF16509.5 AMK79091.1 - 0.039 14.2 0.1 0.092 13.0 0.1 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Sigma70_ECF PF07638.11 AMK79091.1 - 0.061 13.2 0.1 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 ECF sigma factor NUMOD1 PF07453.13 AMK79091.1 - 0.09 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_10 PF04967.12 AMK79091.1 - 0.16 11.8 0.3 0.82 9.5 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain Terminase_5 PF06056.12 AMK79091.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.20 AMK79092.1 - 9.1e-08 32.3 0.3 1.1e-07 32.1 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 AMK79092.1 - 5.3e-06 26.4 0.1 7.1e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 AMK79092.1 - 2e-05 24.2 0.1 2.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_31 PF13560.6 AMK79092.1 - 3.3e-05 24.1 0.3 4.2e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AMK79092.1 - 9.4e-05 22.5 0.1 0.00013 22.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 AMK79092.1 - 0.0041 16.7 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AMK79092.1 - 0.02 14.6 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 AMK79092.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 AMK79092.1 - 0.023 14.7 0.2 0.031 14.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_1_2 PF13022.6 AMK79092.1 - 0.023 14.8 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF134 PF02001.16 AMK79092.1 - 0.023 15.2 0.0 0.026 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_19 PF12844.7 AMK79092.1 - 0.038 14.0 0.0 0.074 13.1 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_37 PF13744.6 AMK79092.1 - 0.048 13.6 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain KORA PF16509.5 AMK79092.1 - 0.051 13.9 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_7 PF02796.15 AMK79092.1 - 0.064 13.3 0.1 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 AMK79092.1 - 0.066 12.9 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_5 PF06056.12 AMK79092.1 - 0.073 13.0 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Phage_CI_repr PF07022.13 AMK79092.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DDE_Tnp_1_6 PF13751.6 AMK79094.1 - 4.4e-23 81.9 1.1 8.1e-23 81.0 1.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK79094.1 - 5.4e-11 42.6 0.1 1.9e-10 40.8 0.1 1.8 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK79094.1 - 1.3e-10 41.1 1.0 2.5e-07 30.6 0.2 2.5 1 1 1 2 2 2 2 Transposase domain (DUF772) DUF4129 PF13559.6 AMK79094.1 - 0.57 10.5 3.6 2.2 8.6 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4129) AMP-binding PF00501.28 AMK79095.1 - 1.5e-18 66.6 0.2 5e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Trp_halogenase PF04820.14 AMK79096.1 - 8.1e-24 84.3 0.0 5.5e-11 42.0 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 AMK79096.1 - 1.4e-11 44.3 0.0 1.7e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 AMK79096.1 - 4.9e-09 36.0 0.0 1.1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 AMK79096.1 - 1.9e-06 28.0 0.0 2e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AMK79096.1 - 4.8e-06 26.4 0.0 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AMK79096.1 - 1.6e-05 24.3 0.0 7.2e-05 22.2 0.0 1.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK79096.1 - 5.3e-05 22.5 0.0 0.00015 21.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 AMK79096.1 - 6.6e-05 21.8 0.0 0.00018 20.3 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 AMK79096.1 - 6.7e-05 23.4 0.0 0.0031 18.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AMK79096.1 - 0.00043 19.6 0.0 0.00071 18.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AMK79096.1 - 0.00064 19.0 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 AMK79096.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AMK79096.1 - 0.0051 16.0 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A TrkA_N PF02254.18 AMK79096.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain PglD_N PF17836.1 AMK79096.1 - 0.14 12.8 0.0 1.5 9.5 0.0 2.6 3 0 0 3 3 3 0 PglD N-terminal domain ApbA PF02558.16 AMK79096.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ketoacyl-synt PF00109.26 AMK79097.1 - 6.1e-28 98.1 1.7 6.1e-28 98.1 1.7 2.3 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AMK79097.1 - 5e-24 84.6 0.0 1.3e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AMK79097.1 - 1.5e-07 31.0 0.3 4e-06 26.4 0.1 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AMK79097.1 - 0.01 15.6 1.1 0.034 14.0 1.1 2.0 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FabA PF07977.13 AMK79098.1 - 0.026 14.2 0.0 0.041 13.5 0.0 1.4 1 1 0 1 1 1 0 FabA-like domain LEF-4 PF05098.12 AMK79098.1 - 0.082 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 4 (LEF-4) adh_short_C2 PF13561.6 AMK79099.1 - 4.3e-54 183.5 0.1 5.1e-54 183.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AMK79099.1 - 1.7e-48 164.7 0.0 2.1e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK79099.1 - 4.7e-20 72.2 0.1 6.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AMK79099.1 - 0.0002 20.9 0.0 0.00029 20.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AMK79099.1 - 0.071 13.7 0.2 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent IreB PF06135.12 AMK79099.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 IreB regulatory phosphoprotein CENP-F_leu_zip PF10473.9 AMK79099.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ketoacyl-synt PF00109.26 AMK79100.1 - 3.7e-38 131.6 0.2 4.5e-37 128.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AMK79100.1 - 7e-32 109.9 0.5 7e-32 109.9 0.5 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AMK79100.1 - 4.1e-05 23.1 0.4 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain Ketoacyl-synt_2 PF13723.6 AMK79101.1 - 2.3e-55 187.7 0.0 3.2e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 AMK79102.1 - 1.9e-14 53.8 0.6 2.1e-14 53.6 0.6 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 AMK79102.1 - 0.033 14.4 0.7 0.04 14.1 0.7 1.1 1 0 0 1 1 1 0 Acyl-carrier DUF1493 PF07377.12 AMK79102.1 - 0.04 14.4 0.2 0.041 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Rad60-SLD_2 PF13881.6 AMK79102.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PEP-CTERM PF07589.11 AMK79103.1 - 1.1 9.5 6.1 9.4 6.5 0.3 2.8 2 0 0 2 2 2 0 PEP-CTERM motif DUF202 PF02656.15 AMK79103.1 - 2.8 8.4 9.4 0.39 11.2 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF202) FabA PF07977.13 AMK79104.1 - 7.1e-06 25.7 0.1 2.3e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 FabA-like domain Phage_antiter_Q PF06323.11 AMK79104.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q PS-DH PF14765.6 AMK79104.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase Glycos_transf_2 PF00535.26 AMK79105.1 - 1.3e-18 67.4 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AMK79105.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Lip_A_acyltrans PF03279.13 AMK79106.1 - 1e-08 34.7 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase SMAP PF15477.6 AMK79106.1 - 0.19 12.7 0.0 2 9.4 0.0 2.1 1 1 0 1 1 1 0 Small acidic protein family 4HBT_2 PF13279.6 AMK79107.1 - 3.3e-08 34.1 0.1 3.6e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 AMK79107.1 - 7.7e-08 32.6 0.0 1.9e-07 31.3 0.0 1.7 1 1 1 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 AMK79107.1 - 0.00023 20.5 0.1 0.00028 20.2 0.1 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase SmpA_OmlA PF04355.13 AMK79108.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 SmpA / OmlA family p25-alpha PF05517.12 AMK79108.1 - 0.078 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 p25-alpha Trep_dent_lipo PF09710.10 AMK79108.1 - 0.085 11.8 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Rhodanese PF00581.20 AMK79109.1 - 9.1e-13 48.7 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Polysacc_deac_1 PF01522.21 AMK79110.1 - 2.5e-25 88.8 0.0 3.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Acyl-CoA_dh_1 PF00441.24 AMK79111.1 - 5.9e-30 104.5 5.0 8.2e-30 104.0 5.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 AMK79111.1 - 7.6e-18 64.5 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 AMK79111.1 - 1.2e-11 45.2 0.0 3.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 AMK79111.1 - 1.6e-05 25.2 1.6 3e-05 24.3 1.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CxxCxxCC PF03692.15 AMK79112.1 - 3.9e-09 37.1 2.6 5.9e-08 33.3 2.6 2.1 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain P4Ha_N PF08336.11 AMK79113.1 - 0.066 13.2 0.4 0.089 12.8 0.4 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prominin PF05478.11 AMK79113.1 - 0.19 9.7 0.1 0.22 9.5 0.1 1.1 1 0 0 1 1 1 0 Prominin AMP-binding PF00501.28 AMK79114.1 - 1.5e-73 247.9 0.0 3.1e-73 246.8 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AMK79114.1 - 3.6e-14 53.5 0.0 7.1e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 AMK79115.1 - 7.7e-27 94.5 0.5 3.1e-25 89.2 0.5 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AMK79115.1 - 6e-25 87.6 0.1 1e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AMK79115.1 - 2.5e-05 23.8 0.3 4.9e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 AMK79115.1 - 0.0018 18.1 3.3 0.013 15.4 2.1 2.8 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KAsynt_C_assoc PF16197.5 AMK79115.1 - 0.15 12.6 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Thiolase_C PF02803.18 AMK79115.1 - 0.19 11.4 1.3 0.56 9.9 0.2 2.2 2 1 0 2 2 2 0 Thiolase, C-terminal domain Ketoacyl-synt_2 PF13723.6 AMK79116.1 - 1.4e-33 116.4 0.1 1.7e-33 116.2 0.1 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SmpA_OmlA PF04355.13 AMK79117.1 - 3.2e-05 23.6 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 SmpA / OmlA family Trp_halogenase PF04820.14 AMK79118.1 - 7.3e-28 97.6 0.0 7.3e-15 54.8 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 AMK79118.1 - 1.8e-10 40.6 0.0 8.6e-07 28.5 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 AMK79118.1 - 1.7e-08 34.1 0.3 1.3e-06 27.9 0.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AMK79118.1 - 3.5e-08 33.4 0.1 0.00012 21.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AMK79118.1 - 7.1e-08 31.6 0.0 4.5e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 AMK79118.1 - 7.6e-08 32.5 0.0 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 AMK79118.1 - 7.9e-08 32.1 0.3 1.8e-05 24.3 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AMK79118.1 - 1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AMK79118.1 - 3.2e-05 23.2 0.4 5.8e-05 22.3 0.4 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 AMK79118.1 - 8.7e-05 23.0 0.0 0.012 16.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK79118.1 - 0.00013 21.2 0.1 0.0002 20.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 AMK79118.1 - 0.00019 20.6 0.0 0.00064 18.9 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 AMK79118.1 - 0.0016 17.7 0.0 0.0038 16.5 0.0 1.5 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 AMK79118.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 AMK79118.1 - 0.034 13.4 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF1748 PF08520.10 AMK79118.1 - 0.069 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) AAA_3 PF07726.11 AMK79120.1 - 1.5e-60 202.8 0.1 2.6e-60 202.0 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 AMK79120.1 - 2.9e-19 68.7 0.4 7.2e-19 67.4 0.4 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 AMK79120.1 - 9.9e-13 48.3 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AMK79120.1 - 7e-08 33.0 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 AMK79120.1 - 1.3e-05 24.7 0.4 0.0041 16.5 0.1 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AMK79120.1 - 2.9e-05 23.9 0.1 0.00019 21.2 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 AMK79120.1 - 0.00021 21.0 0.0 0.0029 17.4 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 AMK79120.1 - 0.00024 20.3 0.0 0.0022 17.1 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain DUF58 PF01882.18 AMK79121.1 - 1.3e-24 86.3 0.0 2.9e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 DUF11 PF01345.18 AMK79121.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF11 DUF3488 PF11992.8 AMK79122.1 - 0.001 18.1 11.3 0.0013 17.8 11.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) KfrA_N PF11740.8 AMK79123.1 - 3.6e-14 53.4 4.5 3.6e-14 53.4 4.5 4.9 1 1 2 4 4 3 1 Plasmid replication region DNA-binding N-term UPF0242 PF06785.11 AMK79123.1 - 0.00025 21.2 36.6 0.025 14.7 10.0 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 AMK79123.1 - 0.0003 19.8 24.9 0.0003 19.8 24.9 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein BBP1_C PF15272.6 AMK79123.1 - 0.0016 18.3 13.2 0.0016 18.3 13.2 2.4 1 1 2 3 3 3 1 Spindle pole body component BBP1, C-terminal FAM184 PF15665.5 AMK79123.1 - 0.072 12.9 35.8 1.3 8.7 18.4 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B FPP PF05911.11 AMK79123.1 - 0.12 10.5 36.4 1.2 7.3 18.2 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fungal_TACC PF12709.7 AMK79123.1 - 0.24 11.8 22.7 0.13 12.7 2.9 4.9 2 2 4 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins IFT57 PF10498.9 AMK79123.1 - 0.27 10.1 26.8 0.33 9.9 12.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PKcGMP_CC PF16808.5 AMK79123.1 - 0.94 9.4 9.0 0.74 9.7 0.3 3.5 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 AMK79123.1 - 3 7.9 21.0 12 6.0 4.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 AMK79123.1 - 4.8 7.2 17.6 4.6 7.3 7.3 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 AMK79123.1 - 5.3 7.1 41.0 2.9 7.9 10.1 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 AMK79123.1 - 6.3 6.1 36.5 8 5.7 26.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 AMK79123.1 - 7.9 6.9 40.1 27 5.2 20.9 4.0 1 1 3 4 4 4 0 Centromere protein H (CENP-H) Syntaxin-6_N PF09177.11 AMK79123.1 - 9.4 6.9 25.2 12 6.6 4.5 3.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Lectin_N PF03954.14 AMK79123.1 - 9.5 6.0 16.2 0.16 11.7 5.9 3.0 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 AMK79123.1 - 9.8 6.4 25.3 1.5 9.0 1.6 3.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Phage_integrase PF00589.22 AMK79124.1 - 4.3e-21 75.4 0.3 9.2e-21 74.4 0.1 1.7 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.6 AMK79124.1 - 0.0014 19.0 0.0 0.01 16.3 0.0 2.4 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain LysR_substrate PF03466.20 AMK79125.1 - 7.1e-38 130.1 0.1 9.6e-38 129.6 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK79125.1 - 1.2e-17 63.6 0.5 2.1e-17 62.8 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_psq PF05225.16 AMK79125.1 - 2e-05 24.2 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_24 PF13412.6 AMK79125.1 - 0.11 12.1 0.1 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding adh_short PF00106.25 AMK79126.1 - 4.3e-09 36.1 0.0 3e-07 30.1 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 AMK79126.1 - 0.00028 20.4 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 AMK79126.1 - 0.0027 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 AMK79126.1 - 0.0044 16.4 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 AMK79126.1 - 0.016 15.2 0.8 0.029 14.3 0.7 1.5 1 1 0 1 1 1 0 KR domain DFP PF04127.15 AMK79126.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Oxidored_FMN PF00724.20 AMK79127.1 - 5.6e-68 229.7 0.0 9.3e-68 229.0 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pirin PF02678.16 AMK79128.1 - 4.7e-15 55.5 0.0 6.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 AMK79128.1 - 0.0017 18.7 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Isochorismatase PF00857.20 AMK79129.1 - 2.2e-20 73.6 0.0 4.7e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family HlyD_D23 PF16576.5 AMK79130.1 - 7.5e-23 80.9 6.4 2.5e-21 75.9 6.4 2.8 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK79130.1 - 3.4e-19 69.5 0.1 3e-17 63.3 0.0 2.7 2 1 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK79130.1 - 5.8e-12 45.2 1.8 9.7e-12 44.5 0.1 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK79130.1 - 8.4e-05 22.3 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.20 AMK79130.1 - 0.00032 20.5 2.1 0.003 17.4 1.0 2.3 1 1 1 2 2 2 1 HlyD membrane-fusion protein of T1SS OB_aCoA_assoc PF01796.17 AMK79130.1 - 0.0047 16.9 0.6 1.7 8.7 0.0 3.3 3 1 0 3 3 3 1 DUF35 OB-fold domain, acyl-CoA-associated YfdX PF10938.8 AMK79130.1 - 0.063 13.2 8.8 0.31 11.0 8.0 2.4 1 1 1 2 2 2 0 YfdX protein MBD PF01429.19 AMK79130.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain OEP PF02321.18 AMK79130.1 - 0.49 10.2 23.6 0.046 13.5 8.5 2.9 1 1 1 2 2 2 0 Outer membrane efflux protein ATP-synt_DE PF00401.20 AMK79130.1 - 1.9 8.8 24.3 0.089 13.1 6.3 3.6 2 1 1 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Atg14 PF10186.9 AMK79130.1 - 7.6 5.5 8.6 11 5.0 8.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran PF00005.27 AMK79131.1 - 3e-59 199.5 0.0 3.3e-28 98.9 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 AMK79131.1 - 3e-20 73.2 0.6 4.1e-05 23.5 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AMK79131.1 - 1.9e-08 35.1 0.4 0.00037 21.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 AMK79131.1 - 3.1e-07 30.0 2.2 0.0071 16.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 AMK79131.1 - 5e-05 23.7 0.0 0.68 10.4 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AMK79131.1 - 5.8e-05 23.0 0.2 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_27 PF13514.6 AMK79131.1 - 0.00013 21.6 0.1 0.0023 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KdpD PF02702.17 AMK79131.1 - 0.00015 21.3 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 Osmosensitive K+ channel His kinase sensor domain AAA_22 PF13401.6 AMK79131.1 - 0.00042 20.6 0.8 0.3 11.4 0.1 3.5 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 AMK79131.1 - 0.00079 19.2 0.5 0.14 11.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 AMK79131.1 - 0.00079 19.6 0.0 5.3 7.3 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AMK79131.1 - 0.0011 19.4 0.2 0.2 12.1 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain Mg_chelatase PF01078.21 AMK79131.1 - 0.0012 18.3 0.4 0.58 9.5 0.1 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AMK79131.1 - 0.0013 18.8 1.3 1.5 8.8 0.1 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 AMK79131.1 - 0.0021 17.7 0.1 0.26 10.9 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 AMK79131.1 - 0.0033 17.4 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain SMC_N PF02463.19 AMK79131.1 - 0.0058 16.1 0.2 7.8 5.9 0.0 3.7 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 AMK79131.1 - 0.006 16.7 0.7 5.2 7.2 0.1 2.7 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 AMK79131.1 - 0.0077 16.4 0.1 1.7 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 AMK79131.1 - 0.0078 16.6 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 AMK79131.1 - 0.02 14.2 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 AMK79131.1 - 0.022 14.8 0.7 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 AMK79131.1 - 0.022 14.5 0.2 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cdc6_C PF09079.11 AMK79131.1 - 0.032 14.2 0.0 8.7 6.4 0.0 2.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain AAA_15 PF13175.6 AMK79131.1 - 0.042 13.5 0.0 12 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.6 AMK79131.1 - 0.083 12.9 0.0 15 5.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 AMK79131.1 - 0.11 12.5 0.2 9.8 6.1 0.0 2.8 3 0 0 3 3 2 0 NTPase MukB PF04310.12 AMK79131.1 - 0.17 11.7 1.1 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_18 PF13238.6 AMK79131.1 - 0.23 12.0 0.4 6.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AMK79131.1 - 0.34 10.5 2.1 3.3 7.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 AMK79131.1 - 0.71 9.4 3.7 0.84 9.2 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 AMK79132.1 - 9.6e-39 133.4 8.4 1.1e-38 133.2 8.4 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AMK79132.1 - 5.4e-36 124.3 7.2 6.9e-36 124.0 7.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AMK79132.1 - 4.6e-24 85.0 23.6 5e-21 75.1 14.8 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC2_membrane_4 PF12730.7 AMK79132.1 - 1.3e-07 31.8 8.3 1.3e-07 31.8 8.3 2.5 2 1 1 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AMK79132.1 - 0.18 11.3 14.9 0.042 13.4 10.2 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AMK79133.1 - 1.7e-40 139.2 16.0 2.2e-40 138.8 16.0 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AMK79133.1 - 1.8e-29 102.7 15.0 1.8e-29 102.7 15.0 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AMK79133.1 - 1.3e-22 80.4 10.0 1.6e-22 80.2 10.0 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AMK79133.1 - 2.2e-05 24.5 8.7 2.2e-05 24.5 8.7 2.2 3 1 0 3 3 3 1 ABC-2 family transporter protein DUF3937 PF13073.6 AMK79133.1 - 0.088 12.9 1.1 0.27 11.4 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) OEP PF02321.18 AMK79134.1 - 3.2e-53 180.3 19.2 1.7e-28 99.7 6.2 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein DDE_Tnp_Tn3 PF01526.17 AMK79135.1 - 5.3e-151 502.8 0.0 7.4e-151 502.3 0.0 1.2 1 0 0 1 1 1 1 Tn3 transposase DDE domain DUF4158 PF13700.6 AMK79135.1 - 3.9e-34 117.9 0.6 3.9e-34 117.9 0.6 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4158) WYL PF13280.6 AMK79136.1 - 5.3e-09 36.4 0.2 1e-08 35.4 0.1 1.5 2 0 0 2 2 2 1 WYL domain Multi_ubiq PF14452.6 AMK79137.1 - 1.8e-20 72.9 0.7 1.5e-09 37.9 0.0 3.1 3 0 0 3 3 3 3 Multiubiquitin Prok-E2_E PF14462.6 AMK79138.1 - 2.4e-11 43.5 0.0 3.1e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family E ThiF PF00899.21 AMK79139.1 - 2.6e-37 128.5 0.0 4.5e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family Prok-JAB PF14464.6 AMK79139.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain APH PF01636.23 AMK79140.1 - 0.00055 19.9 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 AMK79140.1 - 0.029 13.7 0.1 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF3375 PF11855.8 AMK79142.1 - 1.3e-84 284.9 18.1 1.4e-84 284.7 18.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) Pox_A_type_inc PF04508.12 AMK79142.1 - 0.00054 19.7 1.1 0.0073 16.1 0.4 3.0 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat DNA_repr_REX1B PF14966.6 AMK79142.1 - 0.49 11.1 2.6 5.4 7.8 0.1 2.8 3 1 0 3 3 3 0 DNA repair REX1-B DUF4194 PF13835.6 AMK79143.1 - 4.4e-31 107.9 2.7 2e-30 105.7 0.7 1.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4194) Cdc6_C PF09079.11 AMK79143.1 - 0.047 13.7 0.1 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain SbcCD_C PF13558.6 AMK79144.1 - 1.9e-17 63.3 0.0 7.5e-17 61.4 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Baculo_PEP_C PF04513.12 AMK79144.1 - 0.0021 18.1 12.4 0.047 13.7 2.9 4.1 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ORF6C PF10552.9 AMK79144.1 - 0.74 9.9 4.1 1.8 8.7 0.2 3.1 2 1 0 2 2 2 0 ORF6C domain XhlA PF10779.9 AMK79144.1 - 1.6 9.0 12.8 3.1 8.1 1.0 4.3 3 0 0 3 3 3 0 Haemolysin XhlA Allexi_40kDa PF05549.11 AMK79144.1 - 2.8 7.4 9.3 8.4 5.8 0.5 3.7 2 1 1 3 3 3 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 AMK79144.1 - 7 7.2 15.1 8.4 6.9 1.6 4.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein CSN5_C PF18323.1 AMK79144.1 - 9.5 7.2 13.3 0.22 12.5 0.6 4.0 3 2 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF2220 PF09983.9 AMK79145.1 - 7.4e-42 142.8 0.0 1.1e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF3322 PF11795.8 AMK79145.1 - 5.3e-39 134.2 2.2 7.8e-39 133.7 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF4129 PF13559.6 AMK79146.1 - 3.2e-08 33.7 6.8 3.2e-08 33.7 6.8 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4129) DUF2207 PF09972.9 AMK79146.1 - 0.15 10.8 0.3 0.17 10.6 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Patched PF02460.18 AMK79146.1 - 0.22 9.5 0.6 0.31 9.0 0.6 1.1 1 0 0 1 1 1 0 Patched family TLV_coat PF00429.19 AMK79146.1 - 0.37 9.4 1.6 0.52 8.9 1.6 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) XFP_N PF09364.10 AMK79147.1 - 2.7e-183 608.8 0.0 3.7e-183 608.4 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 AMK79147.1 - 1.7e-88 295.3 0.0 2.5e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 AMK79147.1 - 1.4e-83 279.0 0.0 1.9e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 AMK79147.1 - 0.061 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4707 PF15806.5 AMK79147.1 - 0.2 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) FeoA PF04023.14 AMK79148.1 - 3.2e-15 56.1 0.0 3.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 FeoA domain FeoB_N PF02421.18 AMK79149.1 - 1.8e-67 225.8 1.7 5.9e-67 224.1 0.3 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Gate PF07670.14 AMK79149.1 - 9.7e-49 164.3 5.8 1.1e-33 115.8 0.0 2.8 2 0 0 2 2 2 2 Nucleoside recognition MMR_HSR1 PF01926.23 AMK79149.1 - 1.4e-23 83.1 0.1 2.8e-23 82.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_C PF07664.12 AMK79149.1 - 4.2e-22 77.6 0.8 2.3e-21 75.2 0.8 2.4 1 0 0 1 1 1 1 Ferrous iron transport protein B C terminus FeoB_Cyto PF17910.1 AMK79149.1 - 6.2e-15 55.5 0.3 1.2e-14 54.6 0.3 1.5 1 0 0 1 1 1 1 FeoB cytosolic helical domain SRPRB PF09439.10 AMK79149.1 - 4.2e-06 26.3 0.0 8.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 AMK79149.1 - 5.3e-06 26.1 2.0 0.0018 17.9 2.0 3.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 AMK79149.1 - 6.1e-06 26.4 0.6 0.026 14.6 0.1 2.3 1 1 1 2 2 2 2 Dynamin family PduV-EutP PF10662.9 AMK79149.1 - 0.00039 20.2 0.3 0.0012 18.7 0.3 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 AMK79149.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 AMK79149.1 - 0.0035 16.9 0.1 0.048 13.3 0.1 2.2 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 AMK79149.1 - 0.0045 16.9 3.4 0.7 9.8 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase LptF_LptG PF03739.14 AMK79149.1 - 0.0058 15.5 0.6 0.0058 15.5 0.6 2.3 2 1 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG ATP_bind_1 PF03029.17 AMK79149.1 - 0.04 13.7 0.2 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 AMK79149.1 - 0.081 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FeoC PF09012.10 AMK79150.1 - 3.1e-24 84.8 0.0 3.4e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 FeoC like transcriptional regulator DUF89 PF01937.19 AMK79150.1 - 0.1 11.5 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF89 Lactonase PF10282.9 AMK79152.1 - 9.2e-22 77.8 2.3 1.6e-11 44.1 0.0 4.0 1 1 3 4 4 4 3 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 AMK79152.1 - 8.3e-18 64.0 7.1 2.1e-05 23.3 0.1 3.2 1 1 1 3 3 3 3 Cytochrome D1 heme domain Arylesterase PF01731.20 AMK79152.1 - 2.4e-12 46.9 1.2 0.033 14.4 0.0 5.2 4 1 1 5 5 5 3 Arylesterase SGL PF08450.12 AMK79152.1 - 3.5e-09 36.6 2.1 5.2e-06 26.2 0.0 3.6 1 1 2 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Glu_cyclase_2 PF05096.12 AMK79152.1 - 2.4e-08 33.8 1.8 0.0019 17.7 0.2 2.2 1 1 1 2 2 2 2 Glutamine cyclotransferase NHL PF01436.21 AMK79152.1 - 1e-07 31.6 1.9 2.4 8.4 0.0 6.6 7 0 0 7 7 7 2 NHL repeat PQQ_3 PF13570.6 AMK79152.1 - 1.9e-05 25.0 3.2 5 7.7 0.2 5.6 6 0 0 6 6 6 2 PQQ-like domain DUF4221 PF13970.6 AMK79152.1 - 8.8e-05 22.2 0.4 19 4.6 0.0 4.4 1 1 3 5 5 5 0 Domain of unknown function (DUF4221) DUF5128 PF17170.4 AMK79152.1 - 0.00011 21.5 0.0 0.1 11.8 0.0 2.4 2 0 0 2 2 2 2 6-bladed beta-propeller ANAPC4_WD40 PF12894.7 AMK79152.1 - 0.0035 17.6 1.6 9.2 6.6 0.0 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 AMK79152.1 - 0.12 11.5 0.0 3.7 6.5 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) RPE65 PF03055.15 AMK79152.1 - 0.12 11.5 0.2 27 3.8 0.0 3.0 2 1 1 3 3 3 0 Retinal pigment epithelial membrane protein CBM_5_12_2 PF14600.6 AMK79152.1 - 0.15 12.1 0.1 9 6.3 0.0 2.6 2 0 0 2 2 2 0 Cellulose-binding domain Med16 PF11635.8 AMK79152.1 - 0.15 10.0 0.4 0.27 9.1 0.1 1.6 2 0 0 2 2 2 0 Mediator complex subunit 16 Polyketide_cyc2 PF10604.9 AMK79153.1 - 1e-26 93.9 0.2 4.2e-26 91.9 0.2 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 AMK79153.1 - 0.0067 16.2 0.0 0.027 14.2 0.0 2.0 1 1 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc PF03364.20 AMK79153.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Exonuc_X-T_C PF08411.10 AMK79154.1 - 1.9e-95 319.0 0.1 2.6e-95 318.6 0.1 1.2 1 0 0 1 1 1 1 Exonuclease C-terminal RNase_T PF00929.24 AMK79154.1 - 1.1e-22 81.3 0.0 1.8e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF2993 PF11209.8 AMK79154.1 - 0.033 14.4 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) DREV PF05219.12 AMK79154.1 - 0.042 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Aminotran_1_2 PF00155.21 AMK79155.1 - 1.4e-70 238.3 0.0 1.6e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AMK79155.1 - 4.8e-07 29.4 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AMK79155.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 AMK79155.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 AMK79155.1 - 0.019 13.5 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PseudoU_synth_1 PF01416.20 AMK79157.1 - 1.4e-37 128.5 0.0 3.2e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase YkuD PF03734.14 AMK79158.1 - 2.1e-19 70.4 0.0 3.3e-19 69.8 0.0 1.3 1 1 0 1 1 1 1 L,D-transpeptidase catalytic domain tRNA_U5-meth_tr PF05958.11 AMK79159.1 - 3e-28 98.9 0.0 1.1e-27 97.0 0.0 1.8 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 AMK79159.1 - 4.9e-14 52.4 0.0 7.9e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AMK79159.1 - 2.6e-10 39.8 0.0 3.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AMK79159.1 - 5.4e-09 36.7 0.0 1.5e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AMK79159.1 - 1.5e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 AMK79159.1 - 2.5e-07 30.7 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TRAM PF01938.20 AMK79159.1 - 2.5e-07 30.6 0.2 1.2e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 TRAM domain Met_10 PF02475.16 AMK79159.1 - 9.3e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.12 AMK79159.1 - 1.7e-05 25.4 0.0 5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AMK79159.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 AMK79159.1 - 0.00027 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 AMK79159.1 - 0.00029 20.4 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 AMK79159.1 - 0.0005 20.0 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain LRR_10 PF18805.1 AMK79159.1 - 0.0021 17.7 0.1 0.0053 16.4 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat TehB PF03848.14 AMK79159.1 - 0.0096 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 AMK79159.1 - 0.022 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltr_RsmB-F PF01189.17 AMK79159.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 AMK79159.1 - 0.036 13.4 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain DOT1 PF08123.13 AMK79159.1 - 0.047 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PALP PF00291.25 AMK79160.1 - 1.5e-65 221.6 0.5 2.5e-65 220.8 0.5 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 AMK79160.1 - 0.055 13.3 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PP_kinase_C_1 PF17941.1 AMK79161.1 - 4.5e-76 254.0 1.7 7.2e-75 250.1 0.0 2.2 1 1 0 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 AMK79161.1 - 5.3e-71 237.6 0.1 1.6e-69 232.8 0.0 2.2 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 AMK79161.1 - 3.5e-60 203.1 0.0 5.9e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 AMK79161.1 - 4.4e-33 113.8 0.3 9.2e-33 112.8 0.3 1.6 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 AMK79161.1 - 7.2e-11 42.1 0.1 6.6e-05 22.8 0.0 3.5 2 1 0 2 2 2 2 PLD-like domain Peripla_BP_6 PF13458.6 AMK79161.1 - 0.041 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein DUF3409 PF11889.8 AMK79161.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) RNase_T PF00929.24 AMK79162.1 - 4e-40 138.0 0.0 5.3e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 AMK79162.1 - 2.5e-06 27.6 0.0 2.9e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 RNase_H superfamily DUF5051 PF16473.5 AMK79162.1 - 7.2e-06 26.1 0.0 1.2e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 AMK79162.1 - 0.036 13.8 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease DUF1631 PF07793.11 AMK79163.1 - 1.1e-78 265.4 0.0 3.9e-78 263.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1631) EAL PF00563.20 AMK79163.1 - 3e-53 180.8 0.0 7.7e-53 179.5 0.0 1.7 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 AMK79163.1 - 2.2e-17 63.3 0.0 4.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain SKA2 PF16740.5 AMK79163.1 - 0.13 12.0 1.3 1 9.2 0.0 2.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 EVE PF01878.18 AMK79164.1 - 1.4e-58 197.0 0.0 1.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 EVE domain AMP_N PF05195.16 AMK79164.1 - 0.13 12.0 0.2 0.66 9.7 0.0 1.9 1 1 1 2 2 2 0 Aminopeptidase P, N-terminal domain Acetyltransf_7 PF13508.7 AMK79165.1 - 2.6e-11 43.8 0.0 3.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AMK79165.1 - 8.7e-11 41.9 0.0 9.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AMK79165.1 - 9.3e-11 42.0 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AMK79165.1 - 6.9e-07 29.4 0.0 9.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AMK79165.1 - 9.6e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AMK79165.1 - 0.00018 21.4 0.0 0.00036 20.4 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 AMK79165.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase rve PF00665.26 AMK79167.1 - 4.9e-31 107.4 0.1 9.9e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 AMK79167.1 - 8.3e-15 54.7 0.1 1.9e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 AMK79167.1 - 9e-09 35.0 0.2 5.3e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AMK79167.1 - 1.6e-08 34.9 0.9 4.6e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 DDE domain HTH_21 PF13276.6 AMK79167.1 - 1.4e-05 25.1 2.8 2.9e-05 24.1 2.8 1.6 1 0 0 1 1 1 1 HTH-like domain DUF924 PF06041.11 AMK79167.1 - 0.08 13.1 1.4 3.3 7.8 0.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Tox-PL-2 PF15643.6 AMK79167.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 1 0 2 2 2 0 Papain fold toxin 2 HTH_Tnp_1 PF01527.20 AMK79168.1 - 2.9e-10 40.3 3.1 4.5e-10 39.7 3.1 1.2 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 AMK79168.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 AMK79168.1 - 0.0012 18.9 0.1 0.0023 18.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK79168.1 - 0.0012 18.5 0.2 0.0024 17.6 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain TPR_7 PF13176.6 AMK79168.1 - 0.03 14.3 2.8 1.4 9.1 0.1 3.0 3 2 0 3 3 3 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 AMK79168.1 - 0.13 12.2 5.2 0.13 12.1 5.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CTP_transf_3 PF02348.19 AMK79169.1 - 1.2e-55 188.9 0.0 1.5e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 AMK79169.1 - 1.3e-12 48.4 0.2 8.7e-12 45.7 0.1 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain Lambda_CIII PF02061.16 AMK79169.1 - 0.059 13.4 0.8 0.31 11.1 0.0 2.6 3 0 0 3 3 3 0 Lambda Phage CIII Trm112p PF03966.16 AMK79170.1 - 6.3e-11 42.7 1.0 1.4e-10 41.6 1.0 1.6 1 1 0 1 1 1 1 Trm112p-like protein LegC3_N PF18654.1 AMK79170.1 - 0.0059 15.9 0.0 0.0059 15.9 0.0 1.0 1 0 0 1 1 1 1 LegC3 N-terminal coiled-coil domain TF_Zn_Ribbon PF08271.12 AMK79170.1 - 0.0059 16.1 0.2 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 TFIIB zinc-binding Rad50_zn_hook PF04423.14 AMK79170.1 - 0.012 15.4 0.7 0.012 15.4 0.7 1.5 2 0 0 2 2 2 0 Rad50 zinc hook motif PhnA_Zn_Ribbon PF08274.12 AMK79170.1 - 0.021 14.7 0.6 0.034 14.1 0.6 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon LpxK PF02606.14 AMK79171.1 - 2.3e-111 372.1 0.0 2.6e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase MobB PF03205.14 AMK79171.1 - 0.025 14.5 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ExbD PF02472.16 AMK79172.1 - 9.6e-24 84.0 0.0 1.1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 AMK79173.1 - 3.9e-32 110.7 0.0 5e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family MFS_1_like PF12832.7 AMK79174.1 - 4.1e-84 282.7 32.6 5.6e-84 282.2 32.6 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 AMK79174.1 - 6.6e-24 84.5 55.1 6e-16 58.3 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 AMK79174.1 - 1.3e-17 63.9 26.8 1.7e-17 63.5 26.8 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter BT1 PF03092.16 AMK79174.1 - 0.002 16.4 5.2 0.002 16.4 5.2 2.2 2 1 0 2 2 2 1 BT1 family Chorismate_synt PF01264.21 AMK79175.1 - 1.1e-138 461.4 0.0 1.3e-138 461.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase MTS PF05175.14 AMK79176.1 - 1.1e-17 64.2 0.0 8.6e-16 57.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 AMK79176.1 - 9.6e-12 44.9 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK79176.1 - 2.4e-08 34.5 0.0 9.3e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 AMK79176.1 - 8.7e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 AMK79176.1 - 1.3e-05 25.2 0.0 0.00042 20.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 AMK79176.1 - 1.4e-05 24.9 0.1 4.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 AMK79176.1 - 1.5e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 AMK79176.1 - 0.00047 19.5 0.0 0.00068 19.0 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 AMK79176.1 - 0.0025 18.5 0.0 0.0051 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AMK79176.1 - 0.0035 18.0 0.0 0.0092 16.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AMK79176.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CUE PF02845.16 AMK79176.1 - 0.02 14.6 0.1 0.051 13.3 0.1 1.6 1 0 0 1 1 1 0 CUE domain Methyltransf_2 PF00891.18 AMK79176.1 - 0.036 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 AMK79176.1 - 0.054 12.8 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TrmK PF04816.12 AMK79176.1 - 0.071 12.6 0.1 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase AviRa PF11599.8 AMK79176.1 - 0.074 12.5 0.7 1.1 8.7 0.0 2.4 2 1 1 3 3 3 0 RRNA methyltransferase AviRa Methyltransf_10 PF05971.12 AMK79176.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase CMAS PF02353.20 AMK79176.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 AMK79176.1 - 0.21 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HDOD PF08668.12 AMK79177.1 - 1.5e-41 142.0 0.0 2.2e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 HDOD domain HD PF01966.22 AMK79177.1 - 8.5e-08 32.4 0.0 1.9e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 HD domain Harakiri PF15196.6 AMK79177.1 - 0.096 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Activator of apoptosis harakiri DUF1481 PF07356.12 AMK79179.1 - 0.099 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) CreD PF06123.12 AMK79180.1 - 1.1e-137 459.3 0.0 1.3e-137 459.2 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein CreD 7TMR-DISM_7TM PF07695.11 AMK79180.1 - 0.01 15.8 16.5 0.019 14.8 16.5 1.4 1 0 0 1 1 1 0 7TM diverse intracellular signalling Romo1 PF10247.9 AMK79180.1 - 0.091 13.1 0.2 0.26 11.7 0.2 1.8 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF805 PF05656.14 AMK79180.1 - 2.6 8.5 6.9 2.9e+02 1.9 6.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Methyltransf_11 PF08241.12 AMK79181.1 - 9e-22 77.5 0.0 1.5e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AMK79181.1 - 7.4e-18 65.1 0.0 1.6e-17 64.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AMK79181.1 - 9e-16 58.0 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AMK79181.1 - 7.4e-13 49.1 0.0 1.2e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AMK79181.1 - 1.1e-12 48.1 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AMK79181.1 - 4.5e-07 29.5 0.0 6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 AMK79181.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 AMK79181.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 AMK79181.1 - 0.00083 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 AMK79181.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 AMK79181.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 AMK79181.1 - 0.16 10.4 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 AMK79181.1 - 0.22 10.9 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PhzC-PhzF PF02567.16 AMK79182.1 - 5.1e-50 170.5 0.0 5.8e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 AMK79182.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Ribonucleas_3_3 PF14622.6 AMK79182.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease-III-like Rieske_2 PF13806.6 AMK79183.1 - 2.5e-41 139.8 0.0 2.9e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_2 PF07992.14 AMK79184.1 - 6.2e-48 163.5 0.7 1.1e-47 162.7 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 AMK79184.1 - 4.3e-20 71.8 0.0 8.5e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 AMK79184.1 - 3.1e-16 59.7 1.6 3.3e-13 50.0 0.2 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 AMK79184.1 - 6e-16 58.5 7.3 1.2e-11 44.7 5.2 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rubredoxin_C PF18267.1 AMK79184.1 - 5.9e-11 42.1 0.1 2.5e-10 40.1 0.1 2.2 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain NIR_SIR_ferr PF03460.17 AMK79184.1 - 1.2e-10 41.1 0.1 4.1e-10 39.4 0.0 2.0 2 0 0 2 2 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 AMK79184.1 - 9.6e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AMK79184.1 - 0.0013 17.9 2.2 0.3 10.1 0.4 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 AMK79184.1 - 0.0014 18.3 0.3 0.089 12.4 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 AMK79184.1 - 0.014 14.5 0.1 0.32 10.0 0.2 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 AMK79184.1 - 0.043 13.1 2.2 0.049 12.9 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 AMK79184.1 - 0.081 12.1 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 AMK79184.1 - 0.15 10.7 0.3 15 4.1 0.0 2.9 2 1 1 3 3 3 0 HI0933-like protein Pyr_redox_dim PF02852.22 AMK79184.1 - 0.27 11.5 1.0 1.4 9.2 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MFS_1 PF07690.16 AMK79185.1 - 8.4e-40 136.8 85.2 6.5e-34 117.4 52.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AMK79185.1 - 3.2e-06 26.3 29.4 0.00092 18.2 12.0 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter ANTAR PF03861.14 AMK79186.1 - 1.9e-17 62.9 0.5 3.4e-17 62.0 0.5 1.5 1 0 0 1 1 1 1 ANTAR domain Response_reg PF00072.24 AMK79186.1 - 7.7e-08 32.5 0.7 7.7e-08 32.5 0.7 1.6 2 0 0 2 2 2 1 Response regulator receiver domain DUF3557 PF12078.8 AMK79186.1 - 0.0069 16.3 0.9 0.1 12.5 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3557) CoA_binding_2 PF13380.6 AMK79186.1 - 0.012 16.1 0.4 0.021 15.3 0.2 1.6 2 0 0 2 2 2 0 CoA binding domain DUF4392 PF14336.6 AMK79186.1 - 0.077 12.4 0.4 0.13 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF3088 PF11287.8 AMK79186.1 - 0.096 12.5 0.6 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) DUF2799 PF10973.8 AMK79187.1 - 1.3e-22 80.0 0.5 1.9e-22 79.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2799) PQQ_3 PF13570.6 AMK79188.1 - 3.8e-05 24.0 12.1 2.2 8.9 0.4 7.7 8 0 0 8 8 8 2 PQQ-like domain PQQ PF01011.21 AMK79188.1 - 0.0065 16.3 1.0 0.54 10.3 0.0 4.1 4 0 0 4 4 4 1 PQQ enzyme repeat Flg_hook PF02120.16 AMK79189.1 - 3.7e-14 52.4 0.3 3e-13 49.5 0.0 2.6 3 0 0 3 3 3 1 Flagellar hook-length control protein FliK BclA_C PF18573.1 AMK79189.1 - 0.27 11.1 1.3 0.46 10.4 0.3 1.9 2 0 0 2 2 2 0 BclA C-terminal domain FBPase PF00316.20 AMK79190.1 - 4e-67 225.3 0.0 5.2e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain HTH_Crp_2 PF13545.6 AMK79191.1 - 1.7e-18 66.3 0.7 3.1e-18 65.5 0.7 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 AMK79191.1 - 4.1e-14 52.4 0.0 6.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Crp PF00325.20 AMK79191.1 - 1.6e-12 46.9 0.0 3.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family HTH_24 PF13412.6 AMK79191.1 - 0.0013 18.2 0.0 0.004 16.7 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 AMK79191.1 - 0.0025 17.3 0.0 0.0084 15.6 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 AMK79191.1 - 0.0033 17.3 0.1 0.007 16.2 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AMK79191.1 - 0.013 15.4 0.1 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 MarR family RepL PF05732.11 AMK79191.1 - 0.033 13.6 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) HTH_23 PF13384.6 AMK79191.1 - 0.042 13.7 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Phage_rep_org_N PF09681.10 AMK79191.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) ABC2_membrane PF01061.24 AMK79192.1 - 9.7e-32 110.1 18.8 9.7e-32 110.1 18.8 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AMK79192.1 - 3.8e-06 26.3 21.7 3.8e-06 26.3 21.7 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF3980 PF13140.6 AMK79192.1 - 0.098 13.1 3.3 0.081 13.4 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3980) Inositol_P PF00459.25 AMK79192.1 - 0.23 11.0 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family ABC_tran PF00005.27 AMK79193.1 - 5.8e-31 107.8 0.0 1.1e-30 107.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK79193.1 - 1.1e-13 51.7 1.9 1.4e-07 31.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AMK79193.1 - 2.4e-06 27.5 0.0 0.01 15.6 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AMK79193.1 - 2.8e-06 26.9 0.2 1.6e-05 24.5 0.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AMK79193.1 - 0.00014 22.4 0.2 0.00022 21.8 0.1 1.5 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 AMK79193.1 - 0.00018 21.1 0.9 0.00029 20.5 0.1 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 AMK79193.1 - 0.013 15.2 0.1 0.034 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AMK79193.1 - 0.021 14.7 0.2 0.061 13.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_27 PF13514.6 AMK79193.1 - 0.044 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 AMK79193.1 - 0.044 14.0 0.0 0.16 12.2 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 AMK79193.1 - 0.071 13.1 0.4 0.91 9.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AMK79193.1 - 0.093 13.1 0.1 0.6 10.5 0.0 2.2 2 2 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 AMK79193.1 - 0.13 12.6 0.5 2.2 8.7 0.4 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AMK79193.1 - 0.16 12.2 0.6 1.5 9.1 0.1 2.7 2 1 1 3 3 3 0 AAA domain Ppx-GppA PF02541.16 AMK79194.1 - 6.6e-69 232.5 0.1 1e-68 231.9 0.1 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family YqgF PF14639.6 AMK79194.1 - 0.0057 16.4 0.1 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 FtsA PF14450.6 AMK79194.1 - 0.1 13.0 0.8 1.3 9.5 0.2 3.1 3 1 0 3 3 3 0 Cell division protein FtsA DUF2279 PF10043.9 AMK79195.1 - 0.056 14.2 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) Sigma70_r3 PF04539.16 AMK79196.1 - 6.7e-20 71.0 1.9 1.2e-16 60.5 0.4 2.5 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 AMK79196.1 - 1.1e-19 69.9 0.1 2.3e-19 68.9 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AMK79196.1 - 1.8e-17 62.6 0.3 1.3e-14 53.4 0.5 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 AMK79196.1 - 1.3e-09 37.9 0.1 3.5e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 DUF3562 PF12085.8 AMK79196.1 - 0.0016 18.0 0.1 0.28 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3562) HTH_23 PF13384.6 AMK79196.1 - 0.002 17.9 0.1 3.5 7.5 0.0 3.0 3 0 0 3 3 3 2 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AMK79196.1 - 0.018 14.7 0.2 5.9 6.6 0.0 3.0 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 AMK79196.1 - 0.024 14.4 0.1 0.31 10.8 0.0 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain DnaJ PF00226.31 AMK79197.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RsbU_N PF08673.10 AMK79197.1 - 0.038 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain RPAP1_N PF08621.10 AMK79197.1 - 0.22 11.3 1.3 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 RPAP1-like, N-terminal MobB PF03205.14 AMK79198.1 - 1.5e-47 160.8 0.0 1.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 AMK79198.1 - 0.0047 16.5 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain LpxK PF02606.14 AMK79198.1 - 0.0078 15.3 0.0 0.0092 15.1 0.0 1.1 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase PRK PF00485.18 AMK79198.1 - 0.21 11.3 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MoeA_N PF03453.17 AMK79199.1 - 4.9e-36 123.9 0.4 8.1e-36 123.2 0.4 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 AMK79199.1 - 3.1e-26 91.8 0.0 6.3e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 AMK79199.1 - 7.1e-16 58.2 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF3581 PF12119.8 AMK79200.1 - 1.7e-99 331.6 0.1 1.9e-99 331.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3581) Rhodanese PF00581.20 AMK79201.1 - 4.1e-16 59.4 0.0 4.8e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_1_2 PF00155.21 AMK79202.1 - 3.4e-58 197.6 0.0 3.9e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AMK79202.1 - 0.0048 15.8 0.0 0.0079 15.1 0.0 1.3 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 AMK79202.1 - 0.015 13.9 0.0 0.021 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-dskA_traR PF01258.17 AMK79203.1 - 5.6e-12 45.4 2.8 8.5e-12 44.8 2.8 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger tRNA-synt_1c PF00749.21 AMK79204.1 - 1.2e-43 149.2 0.0 5.4e-42 143.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain AMP-binding PF00501.28 AMK79205.1 - 3.2e-93 312.6 0.0 3.8e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 AMK79205.1 - 1.6e-22 79.1 1.4 7.5e-22 77.0 0.6 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 AMK79205.1 - 1.2e-21 77.4 0.2 3.7e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain EamA PF00892.20 AMK79206.1 - 3.1e-27 95.4 38.4 4e-19 69.2 10.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 AMK79206.1 - 0.022 14.8 1.9 0.022 14.8 1.9 2.5 2 1 0 2 2 2 0 Putative transmembrane family 234 DUF1358 PF07096.11 AMK79206.1 - 0.078 13.0 0.6 0.2 11.6 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) DUF4301 PF14134.6 AMK79207.1 - 4.2e-225 748.3 3.7 4.8e-225 748.2 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4301) bVLRF1 PF18826.1 AMK79207.1 - 0.029 14.3 0.1 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor CDC24 PF06395.11 AMK79207.1 - 0.11 12.8 0.0 0.51 10.6 0.0 2.2 1 0 0 1 1 1 0 CDC24 Calponin OEP PF02321.18 AMK79209.1 - 1.4e-59 201.1 26.8 3.9e-30 105.1 5.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein ATP-synt_F PF01990.17 AMK79209.1 - 0.16 12.3 0.2 0.56 10.6 0.1 2.0 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit HCMV_UL139 PF12507.8 AMK79209.1 - 0.19 12.1 2.3 0.26 11.7 0.9 2.0 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF4407 PF14362.6 AMK79209.1 - 1.7 7.9 9.1 0.46 9.8 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_30 PF13604.6 AMK79210.1 - 5.1e-33 114.4 0.2 1.9e-30 106.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 AMK79210.1 - 1.5e-29 103.2 0.1 2.3e-29 102.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AMK79210.1 - 3.6e-15 55.5 0.1 1e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 AMK79210.1 - 4.3e-15 56.0 0.1 7.6e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 AMK79210.1 - 6.6e-12 45.7 0.7 6e-05 22.9 0.0 3.3 2 1 1 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 AMK79210.1 - 1.4e-11 44.7 1.9 6.4e-07 29.4 0.1 2.2 1 1 0 2 2 2 2 AAA domain SH3_13 PF18335.1 AMK79210.1 - 3e-09 36.6 0.0 5.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_22 PF13401.6 AMK79210.1 - 1.2e-08 35.3 0.0 2.6e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 AMK79210.1 - 2.5e-07 30.5 1.1 2.1e-06 27.5 0.1 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 AMK79210.1 - 1.4e-05 24.5 0.0 4.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.6 AMK79210.1 - 0.0031 16.9 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 AMK79210.1 - 0.0059 16.1 0.1 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 AMK79210.1 - 0.0078 16.5 0.4 0.016 15.4 0.4 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 AMK79210.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 AMK79210.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 AMK79210.1 - 0.062 13.7 0.2 0.062 13.7 0.2 2.2 2 1 1 3 3 3 0 AAA ATPase domain DUF853 PF05872.12 AMK79210.1 - 0.096 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.9 AMK79210.1 - 0.1 11.5 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 AMK79210.1 - 0.12 12.4 0.2 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AMK79210.1 - 0.66 10.5 2.5 5.8 7.5 1.9 2.5 2 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.15 AMK79210.1 - 8.6 6.2 7.4 0.17 11.8 0.7 1.6 2 0 0 2 2 1 0 NTPase UvrD-helicase PF00580.21 AMK79211.1 - 8.2e-58 196.4 0.0 3e-57 194.5 0.0 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AMK79211.1 - 2.4e-24 86.4 0.0 2.7e-21 76.3 0.0 3.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AMK79211.1 - 2.1e-17 63.8 0.0 8.5e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AMK79211.1 - 9.9e-12 44.5 0.2 0.00023 20.9 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 AMK79211.1 - 6.2e-06 26.3 0.5 2.7e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 AMK79211.1 - 6.7e-05 22.7 0.0 0.017 14.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 AMK79211.1 - 0.0048 16.5 0.0 0.23 11.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 AMK79211.1 - 0.0055 16.5 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AMK79211.1 - 0.02 14.2 0.0 3.8 6.6 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) FANCI_S1-cap PF14674.6 AMK79211.1 - 0.18 12.0 0.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 FANCI solenoid 1 cap Exonuc_V_gamma PF04257.14 AMK79212.1 - 2.2e-266 886.0 8.5 2.8e-266 885.7 8.5 1.1 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 AMK79212.1 - 3.7e-44 150.9 5.4 3e-43 148.0 4.0 2.8 2 0 0 2 2 2 1 RecC C-terminal domain TPMT PF05724.11 AMK79214.1 - 3.1e-77 259.1 0.2 3.4e-77 259.0 0.2 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 AMK79214.1 - 0.051 14.2 0.0 0.092 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PepSY_TM PF03929.16 AMK79215.1 - 4.4e-18 65.9 12.8 8.2e-13 48.7 7.2 2.6 1 1 0 2 2 2 2 PepSY-associated TM region Cytochrom_B561 PF03188.16 AMK79215.1 - 0.018 15.2 0.7 0.57 10.3 0.3 2.5 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 CD225 PF04505.12 AMK79215.1 - 0.063 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Interferon-induced transmembrane protein AhpC-TSA PF00578.21 AMK79216.1 - 6.9e-25 87.4 0.0 8.3e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK79216.1 - 1.4e-15 57.3 0.0 1.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Cytochrom_C PF00034.21 AMK79217.1 - 1.7e-13 51.5 2.9 7.1e-06 27.1 0.0 3.2 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 AMK79217.1 - 4.6e-12 46.1 0.6 0.0001 22.5 0.2 2.5 2 1 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III DUF1924 PF09086.11 AMK79217.1 - 0.0063 16.8 0.1 2.5 8.5 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1924) PSCyt1 PF07635.11 AMK79217.1 - 0.012 16.2 3.0 0.11 13.2 0.1 2.6 2 0 0 2 2 2 0 Planctomycete cytochrome C Cytochrom_c3_2 PF14537.6 AMK79217.1 - 0.019 15.4 0.1 3.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c3 Paired_CXXCH_1 PF09699.10 AMK79217.1 - 0.02 14.6 0.4 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF2059 PF09832.9 AMK79217.1 - 0.048 13.7 0.4 0.86 9.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) CCP_MauG PF03150.14 AMK79217.1 - 0.11 13.2 0.3 4.2 8.0 0.0 2.2 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase Cytochrome_C7 PF14522.6 AMK79217.1 - 0.14 12.2 3.9 14 5.8 4.1 2.3 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF3365 PF11845.8 AMK79217.1 - 1 9.7 3.1 15 5.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) AhpC-TSA PF00578.21 AMK79218.1 - 1.1e-26 93.2 0.0 1.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AMK79218.1 - 3e-16 59.4 0.0 4.1e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Cytochrom_C_2 PF01322.20 AMK79219.1 - 6.7e-05 23.8 12.2 0.00034 21.5 4.5 2.1 2 0 0 2 2 2 2 Cytochrome C' Cytochrom_B562 PF07361.11 AMK79219.1 - 0.00026 21.6 5.8 0.01 16.5 5.8 2.1 1 1 1 2 2 2 2 Cytochrome b562 DUF4363 PF14276.6 AMK79219.1 - 0.0061 16.7 2.4 0.42 10.7 0.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4363) ABC_tran_CTD PF16326.5 AMK79219.1 - 0.48 10.7 3.6 1.1 9.5 1.2 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain HSCB_C PF07743.13 AMK79219.1 - 1.1 9.7 4.8 5.5 7.5 0.6 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Rotamase PF00639.21 AMK79219.1 - 4.3 8.4 7.2 2 9.4 1.0 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain Phage_holin_7_1 PF16081.5 AMK79219.1 - 8.6 6.5 8.2 6.2 7.0 0.1 2.8 1 1 2 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF1501 PF07394.12 AMK79220.1 - 1.4e-132 442.4 0.0 1.7e-132 442.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Sulfatase PF00884.23 AMK79220.1 - 0.014 14.8 0.1 0.035 13.5 0.0 1.6 1 1 0 1 1 1 0 Sulfatase PSD1 PF07587.11 AMK79221.1 - 1.4e-92 309.7 0.0 2.2e-92 309.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) PSCyt2 PF07583.11 AMK79221.1 - 1.8e-82 276.3 0.1 4.1e-82 275.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1549) LytR_C PF13399.6 AMK79222.1 - 0.0019 19.1 0.0 0.0037 18.2 0.0 1.4 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator DUF4148 PF13663.6 AMK79222.1 - 0.12 12.5 1.0 0.19 12.0 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Rhodanese PF00581.20 AMK79222.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain PepSY_2 PF13670.6 AMK79222.1 - 0.84 9.7 3.1 0.53 10.3 1.2 1.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain SGL PF08450.12 AMK79223.1 - 4.1e-42 144.5 0.0 5.3e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 AMK79223.1 - 1.9e-07 31.1 0.1 0.041 14.0 0.0 3.8 4 1 0 4 4 4 2 Strictosidine synthase Arylesterase PF01731.20 AMK79223.1 - 2.8e-07 30.6 0.0 5.9e-06 26.4 0.0 2.8 3 0 0 3 3 3 1 Arylesterase NHL PF01436.21 AMK79223.1 - 2e-06 27.6 0.4 1.6 8.9 0.0 4.3 4 0 0 4 4 4 2 NHL repeat Lactonase PF10282.9 AMK79223.1 - 0.0012 18.2 0.0 0.0033 16.7 0.0 1.7 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Reg_prop PF07494.11 AMK79223.1 - 0.078 13.2 0.1 3 8.4 0.0 3.3 3 0 0 3 3 3 0 Two component regulator propeller SdiA-regulated PF06977.11 AMK79223.1 - 0.16 11.2 0.0 7.2 5.8 0.0 2.7 2 1 0 3 3 3 0 SdiA-regulated TonB_dep_Rec PF00593.24 AMK79224.1 - 6.1e-30 105.5 33.8 1e-29 104.7 33.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK79224.1 - 1.2e-12 48.4 1.0 6.5e-12 46.0 0.3 2.6 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 AMK79225.1 - 1e-23 85.0 50.3 1e-23 85.0 50.3 3.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK79225.1 - 7.8e-13 48.9 1.4 7.8e-13 48.9 1.4 3.2 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain DUF5024 PF16427.5 AMK79225.1 - 0.022 15.1 1.4 1 9.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) bZIP_2 PF07716.15 AMK79225.1 - 0.1 12.7 0.8 0.2 11.8 0.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper IHABP4_N PF16174.5 AMK79225.1 - 0.3 11.7 2.7 0.64 10.6 2.7 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ribosomal_60s PF00428.19 AMK79225.1 - 6.9 7.3 14.6 9.3 6.9 13.4 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein EKR PF10371.9 AMK79226.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Cupin_7 PF12973.7 AMK79227.1 - 0.0055 16.6 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.6 AMK79227.1 - 0.076 12.1 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Sigma54_activat PF00158.26 AMK79228.1 - 1.5e-67 226.5 0.0 2e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 AMK79228.1 - 6.1e-18 65.3 0.0 1.5e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 AMK79228.1 - 4.9e-07 29.8 0.0 8.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 AMK79228.1 - 5.4e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Mg_chelatase PF01078.21 AMK79228.1 - 0.00063 19.2 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 AMK79228.1 - 0.0028 18.1 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK79228.1 - 0.026 14.9 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 AMK79228.1 - 0.043 14.1 0.2 2.6 8.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 AMK79228.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 AMK79228.1 - 0.068 12.9 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain MttA_Hcf106 PF02416.16 AMK79229.1 - 1.9e-15 55.9 0.0 2.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family ACR_tran PF00873.19 AMK79230.1 - 1e-205 685.6 11.9 1.2e-205 685.4 11.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK79230.1 - 0.062 12.2 41.1 0.015 14.2 18.7 2.6 2 0 0 2 2 2 0 MMPL family HlyD_D23 PF16576.5 AMK79231.1 - 9.8e-23 80.5 0.5 1.6e-22 79.8 0.5 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK79231.1 - 6.2e-17 62.2 0.9 3.3e-15 56.7 0.3 2.5 2 0 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK79231.1 - 6.8e-10 38.6 0.4 8.7e-08 31.9 0.3 3.1 2 1 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK79231.1 - 0.0049 16.7 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme PYNP_C PF07831.13 AMK79231.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Desulfoferrodox PF01880.18 AMK79232.1 - 3.8e-08 33.8 0.0 5.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Desulfoferrodoxin TAT_signal PF10518.9 AMK79232.1 - 0.0022 17.8 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence HEPN_Apea PF18739.1 AMK79233.1 - 1.5e-15 57.5 2.1 2.3e-15 56.8 0.8 2.0 1 1 1 2 2 2 1 Apea-like HEPN VanY PF02557.17 AMK79234.1 - 2.7e-39 134.0 0.0 3.2e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase NTP_transf_3 PF12804.7 AMK79235.1 - 4.8e-40 137.5 3.4 5.9e-40 137.2 3.4 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 AMK79235.1 - 2e-07 31.0 0.5 2.8e-07 30.5 0.5 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 AMK79235.1 - 3.9e-05 23.4 0.1 5.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase XdhC_C PF13478.6 AMK79236.1 - 3.8e-33 114.7 0.0 7.3e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 AMK79236.1 - 1.5e-19 69.9 0.0 4.8e-18 65.1 0.0 2.3 2 0 0 2 2 2 1 XdhC and CoxI family Ald_Xan_dh_C2 PF02738.18 AMK79237.1 - 9e-72 242.3 0.0 6.4e-37 127.2 0.0 3.5 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase TAT_signal PF10518.9 AMK79237.1 - 0.44 10.5 2.7 0.54 10.2 0.3 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Fer2_2 PF01799.20 AMK79238.1 - 7.7e-26 89.9 3.0 1.1e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 AMK79238.1 - 2.9e-09 36.7 0.2 2.9e-09 36.7 0.2 1.7 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 AMK79238.1 - 1.8e-07 31.1 0.5 3.8e-07 30.1 0.5 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 AMK79238.1 - 0.00041 20.1 3.8 0.0013 18.5 3.8 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2_4 PF13510.6 AMK79238.1 - 0.00084 19.3 0.8 0.0026 17.8 0.8 1.9 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NinG PF05766.12 AMK79238.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein SMBP PF16785.5 AMK79239.1 - 2.6e-29 101.7 26.8 2.9e-29 101.5 26.8 1.0 1 0 0 1 1 1 1 Small metal-binding protein Fae PF08714.11 AMK79240.1 - 8.8e-69 230.5 2.2 9.9e-69 230.3 2.2 1.0 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) Lactamase_B PF00753.27 AMK79241.1 - 4.4e-10 39.9 0.1 7.5e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AMK79241.1 - 0.00039 20.0 0.2 0.0031 17.1 0.1 2.2 1 1 0 2 2 2 1 Beta-lactamase superfamily domain DUF885 PF05960.11 AMK79242.1 - 1.5e-78 265.7 6.5 1.7e-78 265.6 6.5 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Cupin_1 PF00190.22 AMK79243.1 - 2.6e-06 27.1 0.1 3.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 AMK79243.1 - 2.5e-05 23.9 0.1 7.4e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 AMK79243.1 - 6.2e-05 22.7 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Auxin binding protein Cupin_7 PF12973.7 AMK79243.1 - 0.0025 17.7 0.0 0.0043 16.9 0.0 1.6 1 1 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.6 AMK79243.1 - 0.0028 16.8 0.0 0.0071 15.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4437) baeRF_family10 PF18854.1 AMK79243.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Mpt_N PF09176.11 AMK79244.1 - 1.1e-33 115.1 1.9 3.1e-33 113.8 1.9 1.8 1 0 0 1 1 1 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal ELFV_dehydrog PF00208.21 AMK79244.1 - 0.00018 21.3 0.5 0.00033 20.5 0.4 1.4 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 AMK79244.1 - 0.00019 20.8 0.6 0.0003 20.1 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 AMK79244.1 - 0.00093 19.6 0.3 0.0018 18.6 0.3 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 AMK79244.1 - 0.00099 18.5 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 AMK79244.1 - 0.0079 16.7 0.2 0.021 15.4 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 AMK79244.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AMK79244.1 - 0.013 15.6 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 AMK79244.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EAL PF00563.20 AMK79245.1 - 2.6e-70 236.7 1.7 5.8e-70 235.5 0.2 2.3 3 0 0 3 3 3 1 EAL domain GGDEF PF00990.21 AMK79245.1 - 9.5e-47 158.7 0.0 2.2e-46 157.5 0.0 1.7 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 AMK79245.1 - 3.4e-45 152.6 0.2 2.1e-18 66.5 0.0 5.1 4 1 0 4 4 4 3 PAS domain PAS PF00989.25 AMK79245.1 - 1.7e-36 124.6 0.1 3.3e-13 49.6 0.0 4.4 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 AMK79245.1 - 2.8e-31 108.0 0.0 1.9e-08 34.5 0.0 4.9 4 1 0 4 4 4 4 PAS fold PAS_8 PF13188.7 AMK79245.1 - 1.9e-24 85.1 0.0 6.4e-06 26.1 0.0 4.8 4 0 0 4 4 4 4 PAS domain PAS_3 PF08447.12 AMK79245.1 - 3.8e-19 68.7 0.0 3.2e-08 33.8 0.0 4.1 4 0 0 4 4 4 2 PAS fold PAS_7 PF12860.7 AMK79245.1 - 6.9e-11 42.3 1.9 0.36 11.0 0.0 6.5 5 2 0 5 5 5 3 PAS fold PAS_12 PF18095.1 AMK79245.1 - 0.012 15.3 0.1 16 5.1 0.0 3.6 4 0 0 4 4 4 0 UPF0242 C-terminal PAS-like domain TetR_C_32 PF09209.11 AMK79247.1 - 4e-21 75.3 0.8 7.1e-21 74.5 0.8 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 AMK79247.1 - 8.9e-12 44.6 0.1 1.4e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_30 PF17939.1 AMK79247.1 - 0.018 15.2 0.2 0.032 14.4 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Biotin_lipoyl_2 PF13533.6 AMK79248.1 - 2.7e-16 59.1 11.5 1.1e-15 57.1 0.4 3.8 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 AMK79248.1 - 3.7e-14 52.5 2.3 7.3e-14 51.5 2.3 1.5 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK79248.1 - 3.2e-12 47.1 4.9 6.1e-08 33.3 0.2 3.3 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 AMK79248.1 - 0.00044 20.0 0.9 0.032 14.0 0.1 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 AMK79248.1 - 0.0039 16.9 0.4 0.35 10.6 0.0 3.1 3 0 0 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 VWA_3_C PF18571.1 AMK79248.1 - 0.028 14.3 0.4 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain ACR_tran PF00873.19 AMK79249.1 - 0 1105.8 20.5 0 1105.6 20.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK79249.1 - 1e-09 37.8 9.1 1e-09 37.8 9.1 2.6 2 0 0 2 2 2 1 MMPL family SecD_SecF PF02355.16 AMK79249.1 - 0.00018 21.0 26.8 0.0034 16.8 15.4 2.6 2 0 0 2 2 2 2 Protein export membrane protein Man-6-P_recep PF02157.15 AMK79249.1 - 0.16 11.0 0.2 0.33 10.0 0.2 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor ACR_tran PF00873.19 AMK79250.1 - 0 1040.7 11.5 0 1040.5 11.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK79250.1 - 2.8e-08 33.1 10.2 2.8e-08 33.1 10.2 3.1 4 1 1 5 5 5 2 MMPL family SecD_SecF PF02355.16 AMK79250.1 - 0.00019 20.9 19.8 0.00054 19.4 10.7 2.5 2 0 0 2 2 2 2 Protein export membrane protein OEP PF02321.18 AMK79251.1 - 7.6e-45 153.0 35.0 3.5e-24 85.6 14.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Phage_ASH PF10554.9 AMK79251.1 - 0.4 11.0 2.7 3.5 8.0 0.1 3.1 2 1 1 3 3 3 0 Ash protein family Rhomboid PF01694.22 AMK79253.1 - 2.8e-14 53.4 8.6 5.9e-14 52.3 8.6 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 AMK79253.1 - 0.076 13.6 0.1 0.076 13.6 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF5336 PF17270.2 AMK79253.1 - 0.15 11.7 2.9 0.33 10.5 2.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5336) TonB_C PF03544.14 AMK79254.1 - 3.5e-22 78.6 0.0 6.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal TonB_2 PF13103.6 AMK79254.1 - 4.4e-06 26.9 0.1 4.4e-06 26.9 0.1 2.8 2 2 2 4 4 4 1 TonB C terminal TolA PF06519.11 AMK79254.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 TolA C-terminal MotA_ExbB PF01618.16 AMK79255.1 - 6.5e-35 119.6 0.1 1.2e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 AMK79256.1 - 3.5e-26 91.9 0.6 4.1e-26 91.7 0.6 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DLH PF01738.18 AMK79257.1 - 1.6e-50 171.6 0.1 2.2e-50 171.2 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 AMK79257.1 - 8.9e-10 38.4 0.1 4.5e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 AMK79257.1 - 0.00017 21.6 0.3 0.24 11.3 0.0 2.6 1 1 2 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 AMK79257.1 - 0.0045 16.6 0.0 0.016 14.8 0.0 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 AMK79257.1 - 0.0046 16.8 0.1 0.013 15.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AMK79257.1 - 0.02 14.2 0.0 0.063 12.5 0.0 1.8 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Ni_hydr_CYTB PF01292.20 AMK79258.1 - 1e-20 74.1 13.2 1e-20 74.1 13.2 2.1 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 DUF4079 PF13301.6 AMK79258.1 - 0.0034 17.5 4.0 0.025 14.8 3.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) Cytochrom_C_2 PF01322.20 AMK79259.1 - 6.8e-30 104.4 1.1 8.1e-30 104.2 1.1 1.1 1 0 0 1 1 1 1 Cytochrome C' Campylo_MOMP PF05538.11 AMK79259.1 - 0.092 11.7 1.6 0.33 9.9 1.8 1.7 1 1 1 2 2 2 0 Campylobacter major outer membrane protein EAL PF00563.20 AMK79260.1 - 3.3e-10 39.9 0.7 4e-10 39.6 0.7 1.1 1 0 0 1 1 1 1 EAL domain SBP_bac_11 PF13531.6 AMK79261.1 - 2.2e-43 148.7 0.1 2.6e-43 148.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 AMK79261.1 - 2.4e-19 70.5 9.2 3.1e-19 70.1 9.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AMK79261.1 - 3.5e-09 36.4 1.1 4.8e-09 36.0 1.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 AMK79261.1 - 0.00084 18.5 0.1 0.0025 17.0 0.0 1.7 2 0 0 2 2 2 1 PBP superfamily domain DUF3013 PF11217.8 AMK79261.1 - 0.036 13.9 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3013) Alginate_exp PF13372.6 AMK79262.1 - 4.2e-88 295.8 11.5 5.2e-88 295.5 11.5 1.0 1 0 0 1 1 1 1 Alginate export DUF2292 PF10055.9 AMK79263.1 - 1.2e-16 60.0 1.4 1.5e-16 59.8 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2292) T6SS_TssG PF06996.11 AMK79263.1 - 0.02 14.2 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion, TssG PK PF00224.21 AMK79263.1 - 0.048 12.5 0.0 0.048 12.5 0.0 1.0 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain BPD_transp_1 PF00528.22 AMK79264.1 - 1.2e-23 83.8 21.6 1.2e-23 83.8 21.6 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 AMK79265.1 - 2.8e-17 63.1 12.6 2.8e-17 63.1 12.6 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2273 PF10031.9 AMK79265.1 - 0.032 14.3 0.3 0.032 14.3 0.3 4.0 5 0 0 5 5 5 0 Small integral membrane protein (DUF2273) ABC_tran PF00005.27 AMK79266.1 - 2e-35 122.3 0.0 5e-35 121.0 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 AMK79266.1 - 8.1e-10 39.0 1.0 0.00047 20.1 0.2 2.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK79266.1 - 1.6e-06 27.7 0.0 7.5e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE_3 PF12857.7 AMK79266.1 - 3e-06 27.0 0.0 6.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 TOBE-like domain TOBE_2 PF08402.10 AMK79266.1 - 6.4e-05 23.0 0.0 0.00021 21.4 0.0 1.9 1 0 0 1 1 1 1 TOBE domain AAA_16 PF13191.6 AMK79266.1 - 7.1e-05 23.3 0.3 0.00016 22.1 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AMK79266.1 - 0.0002 21.8 0.0 0.0023 18.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AMK79266.1 - 0.00052 20.6 0.0 0.00098 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AMK79266.1 - 0.0012 18.2 0.1 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 KaiC NACHT PF05729.12 AMK79266.1 - 0.0018 18.2 1.0 0.032 14.1 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 AMK79266.1 - 0.0048 16.5 0.7 0.0097 15.5 0.1 1.9 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AMK79266.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 AMK79266.1 - 0.012 15.9 0.1 0.027 14.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 AMK79266.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 AMK79266.1 - 0.019 15.2 0.0 0.063 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 AMK79266.1 - 0.027 13.9 0.0 2.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 AMK79266.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AMK79266.1 - 0.037 14.3 0.2 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 AMK79266.1 - 0.048 13.1 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TOBE PF03459.17 AMK79266.1 - 0.074 13.4 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 1 0 TOBE domain AAA_5 PF07728.14 AMK79266.1 - 0.075 13.0 0.1 0.21 11.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AMK79266.1 - 0.089 12.5 0.4 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AMK79266.1 - 0.12 12.6 0.1 0.79 10.0 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 AMK79266.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 AMK79266.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DLIC PF05783.11 AMK79266.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ABC_ATPase PF09818.9 AMK79266.1 - 0.15 10.8 0.6 7.1 5.3 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class TsaE PF02367.17 AMK79266.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 AMK79266.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 AMK79266.1 - 0.24 11.0 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain LysR_substrate PF03466.20 AMK79267.1 - 1.8e-38 132.0 0.0 2.2e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK79267.1 - 1.6e-14 53.6 0.2 1.1e-13 50.9 0.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 AMK79267.1 - 0.027 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 AMK79267.1 - 0.1 12.5 1.5 0.17 11.8 0.2 2.1 3 0 0 3 3 3 0 MarR family PALP PF00291.25 AMK79268.1 - 1.3e-65 221.7 0.5 1.5e-65 221.6 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_3 PF07859.13 AMK79268.1 - 0.11 12.4 0.1 2.8 7.7 0.2 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2188 PF09954.9 AMK79268.1 - 0.93 9.7 6.5 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Hexapep PF00132.24 AMK79269.1 - 7.2e-11 41.4 4.3 1.7e-06 27.5 1.1 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) SATase_N PF06426.14 AMK79269.1 - 0.0022 18.3 0.1 0.0036 17.6 0.1 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep_2 PF14602.6 AMK79269.1 - 0.0023 17.7 4.4 0.0076 16.0 0.8 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Aminotran_5 PF00266.19 AMK79271.1 - 3.3e-146 487.0 0.2 4.1e-146 486.7 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 AMK79271.1 - 9.1e-08 31.7 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AMK79271.1 - 0.00019 20.8 0.1 0.00047 19.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AMK79271.1 - 0.019 14.3 1.0 0.034 13.5 1.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AMK79271.1 - 0.044 12.3 0.0 0.069 11.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme EcKinase PF02958.20 AMK79272.1 - 2.2e-20 73.2 0.0 1.5e-19 70.4 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 AMK79272.1 - 1.7e-14 54.4 0.7 2.4e-14 53.8 0.7 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 AMK79272.1 - 8.7e-11 41.3 0.1 2.7e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Fic PF02661.18 AMK79273.1 - 3e-07 31.2 0.0 7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family SLT PF01464.20 AMK79274.1 - 2.8e-10 39.9 0.0 6.7e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 AMK79274.1 - 0.066 13.7 0.0 0.26 11.8 0.0 1.9 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase FlhD PF05247.13 AMK79275.1 - 3.4e-11 43.3 0.1 3.9e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF2857 PF11198.8 AMK79275.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) AHL_synthase PF17327.2 AMK79275.1 - 0.065 12.3 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Acyl homoserine lactone synthase DUF3732 PF12532.8 AMK79279.1 - 1.1e-51 175.2 0.0 2.2e-51 174.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3732) AAA_23 PF13476.6 AMK79279.1 - 0.0005 20.6 9.9 0.00067 20.2 4.8 3.1 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 AMK79279.1 - 0.0013 18.6 0.2 0.31 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AMK79279.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 AMK79279.1 - 0.086 12.3 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Trimer_CC PF08954.11 AMK79279.1 - 0.089 12.4 6.9 0.13 11.9 0.6 2.9 3 0 0 3 3 3 0 Trimerisation motif DUF1192 PF06698.11 AMK79279.1 - 1.5 9.0 5.8 0.19 11.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_Maf PF03131.17 AMK79279.1 - 6.8 7.3 7.6 0.65 10.6 1.1 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Peptidase_M48 PF01435.18 AMK79280.1 - 0.0058 16.4 1.0 0.3 10.8 0.0 2.5 3 0 0 3 3 3 2 Peptidase family M48 Het-C PF07217.11 AMK79281.1 - 2.5e-07 29.6 0.0 3.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C MFS_2 PF13347.6 AMK79282.1 - 0.025 13.2 2.3 0.028 13.0 2.3 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4133 PF13571.6 AMK79282.1 - 0.21 11.9 2.2 0.67 10.3 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) TraG_N PF07916.11 AMK79283.1 - 1e-96 324.6 20.3 1e-96 324.6 20.3 3.3 2 1 1 3 3 3 1 TraG-like protein, N-terminal region TraH PF06122.11 AMK79284.1 - 1.4e-103 347.0 4.5 1.4e-103 347.0 4.5 1.4 2 0 0 2 2 2 1 Conjugative relaxosome accessory transposon protein SopA PF13981.6 AMK79284.1 - 0.1 13.0 0.1 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 SopA-like central domain TraF PF13728.6 AMK79285.1 - 4.1e-72 242.6 0.5 5.1e-72 242.3 0.5 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 AMK79285.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF4832 PF16116.5 AMK79286.1 - 0.032 14.1 0.5 0.17 11.7 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4832) TrfA PF07042.11 AMK79288.1 - 2.2e-17 63.0 0.0 2.9e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 TrfA protein RPA PF10134.9 AMK79288.1 - 7.1e-05 22.4 0.0 0.00072 19.1 0.0 2.2 1 1 0 1 1 1 1 Replication initiator protein A Fip1 PF05182.13 AMK79289.1 - 0.25 10.9 1.6 0.83 9.2 0.1 2.1 2 0 0 2 2 2 0 Fip1 motif TraI_2 PF07514.11 AMK79290.1 - 2.4e-97 325.8 0.2 3.1e-97 325.4 0.2 1.2 1 0 0 1 1 1 1 Putative helicase HD PF01966.22 AMK79290.1 - 0.039 14.2 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 HD domain TrwB_AAD_bind PF10412.9 AMK79291.1 - 6.4e-15 54.9 0.0 2.5e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 AMK79291.1 - 7.8e-13 48.5 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG AAA_10 PF12846.7 AMK79291.1 - 4.2e-09 35.8 0.0 7.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 AMK79291.1 - 3.1e-05 24.2 0.0 6.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain T4SS-DNA_transf PF02534.14 AMK79291.1 - 8.4e-05 21.6 0.0 0.0034 16.2 0.0 2.1 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer DUF853 PF05872.12 AMK79291.1 - 0.00023 19.9 0.0 0.00039 19.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) FtsK_SpoIIIE PF01580.18 AMK79291.1 - 0.00025 20.5 0.1 0.0054 16.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 AMK79291.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 AMK79291.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 AMK79291.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4400 PF14348.6 AMK79292.1 - 1.4e-21 77.0 0.8 1.7e-21 76.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) ExoD PF06055.12 AMK79292.1 - 0.0063 15.9 3.0 0.034 13.5 1.1 2.2 2 0 0 2 2 2 1 Exopolysaccharide synthesis, ExoD TauE PF01925.19 AMK79293.1 - 7e-37 127.3 36.5 8.8e-37 127.0 36.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4395 PF14340.6 AMK79293.1 - 3.8 7.9 15.2 1.9 8.8 3.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) HupE_UreJ PF04955.12 AMK79294.1 - 8.5e-44 149.2 16.7 1.4e-43 148.5 16.7 1.2 1 0 0 1 1 1 1 HupE / UreJ protein HupE_UreJ_2 PF13795.6 AMK79294.1 - 0.0085 15.8 12.0 0.015 15.0 12.0 1.3 1 0 0 1 1 1 1 HupE / UreJ protein TonB_dep_Rec PF00593.24 AMK79295.1 - 3.8e-21 76.5 37.3 3.8e-21 76.5 37.3 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 AMK79295.1 - 4.5e-15 56.1 0.4 2.3e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OEP PF02321.18 AMK79297.1 - 8.8e-42 143.0 21.4 1.2e-21 77.3 10.1 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein DUF3879 PF12995.7 AMK79297.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) HlyD_D23 PF16576.5 AMK79298.1 - 3.4e-78 261.7 0.0 4.9e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK79298.1 - 6.8e-18 65.3 0.0 2.9e-16 60.1 0.0 2.6 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.20 AMK79298.1 - 0.0001 22.1 0.1 0.01 15.7 0.1 2.8 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_D4 PF16572.5 AMK79298.1 - 0.023 14.6 1.3 0.57 10.1 0.6 3.0 2 1 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB ACR_tran PF00873.19 AMK79299.1 - 7.9e-238 791.9 5.8 9.4e-238 791.6 5.8 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK79299.1 - 0.0011 18.0 19.3 0.0055 15.7 1.0 2.7 2 1 0 2 2 2 2 MMPL family CMD PF02627.20 AMK79300.1 - 4.8e-12 45.8 0.0 1.5e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DNA_pol3_delta PF06144.13 AMK79300.1 - 0.016 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit E1-E2_ATPase PF00122.20 AMK79302.1 - 1.3e-51 174.7 0.3 1.3e-51 174.7 0.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 AMK79302.1 - 1.4e-41 142.2 6.0 2.9e-41 141.2 6.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 AMK79302.1 - 2.4e-23 83.6 2.2 6.6e-23 82.1 2.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 AMK79302.1 - 2.1e-21 75.8 0.0 4.1e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 AMK79302.1 - 6.6e-17 61.0 0.0 1.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 AMK79302.1 - 2.8e-05 24.0 0.8 0.0009 19.1 1.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 AMK79302.1 - 0.00019 21.9 0.1 0.00053 20.4 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HD_5 PF13487.6 AMK79303.1 - 2.8e-14 53.1 0.0 7.2e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 HD domain HD PF01966.22 AMK79303.1 - 3.7e-13 49.8 0.1 1.1e-12 48.2 0.1 1.9 1 0 0 1 1 1 1 HD domain DUF596 PF04591.12 AMK79303.1 - 0.2 11.8 0.1 1.1 9.4 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function, DUF596 Sda PF08970.10 AMK79304.1 - 0.019 14.7 1.8 0.086 12.6 0.1 2.2 2 0 0 2 2 2 0 Sporulation inhibitor A TEX12 PF15219.6 AMK79304.1 - 0.074 13.4 0.2 0.091 13.1 0.2 1.1 1 0 0 1 1 1 0 Testis-expressed 12 NSF PF02071.20 AMK79304.1 - 0.35 11.8 7.5 12 7.2 0.7 3.0 2 0 0 2 2 2 0 Aromatic-di-Alanine (AdAR) repeat HTH_37 PF13744.6 AMK79305.1 - 1.7e-15 56.7 0.6 2e-15 56.5 0.6 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AMK79305.1 - 0.002 18.1 0.2 0.0032 17.5 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 AMK79305.1 - 0.0024 18.3 0.7 0.0031 17.9 0.7 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 AMK79305.1 - 0.025 14.9 0.1 0.03 14.6 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 AMK79305.1 - 0.082 12.9 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zf_CopZ PF18423.1 AMK79306.1 - 2e-07 30.8 0.1 3.5e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Zinc binding domain HMA PF00403.26 AMK79307.1 - 4.6e-15 55.8 1.0 5.7e-15 55.5 1.0 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain RRM_3 PF08777.11 AMK79307.1 - 0.0054 16.7 0.0 0.0071 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif GRDA PF04723.14 AMK79307.1 - 0.02 14.7 0.5 0.025 14.4 0.5 1.1 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A TusA PF01206.17 AMK79307.1 - 0.096 12.5 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Sulfurtransferase TusA MerT PF02411.15 AMK79308.1 - 5.1e-30 103.9 2.5 5.9e-30 103.7 2.5 1.0 1 0 0 1 1 1 1 MerT mercuric transport protein MerR_1 PF13411.6 AMK79309.1 - 4.7e-19 68.2 0.2 9.6e-19 67.2 0.2 1.6 1 1 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 AMK79309.1 - 2.2e-18 66.6 6.7 1.3e-17 64.1 5.7 2.1 2 0 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 AMK79309.1 - 1.5e-14 53.5 0.7 2.7e-14 52.7 0.7 1.5 1 0 0 1 1 1 1 MerR family regulatory protein Phytochelatin PF05023.14 AMK79309.1 - 0.0098 15.1 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase RepB PF07506.11 AMK79309.1 - 0.036 14.2 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein HTH_20 PF12840.7 AMK79309.1 - 0.037 14.1 0.5 10 6.3 0.1 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 AMK79309.1 - 0.038 14.0 0.2 0.91 9.5 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_23 PF13384.6 AMK79309.1 - 0.083 12.7 1.6 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Osmo_CC PF08946.10 AMK79309.1 - 0.087 13.1 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil OEP PF02321.18 AMK79310.1 - 2.5e-48 164.4 25.6 4.9e-29 101.5 8.5 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein HTH_34 PF13601.6 AMK79310.1 - 0.21 11.8 1.5 0.59 10.3 0.1 2.4 3 0 0 3 3 3 0 Winged helix DNA-binding domain HlyD_3 PF13437.6 AMK79311.1 - 1.6e-13 51.2 5.0 5.2e-11 43.2 0.0 3.0 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 AMK79311.1 - 2.1e-12 46.7 7.7 1.9e-10 40.3 7.7 2.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 AMK79311.1 - 9.5e-09 34.9 1.4 9.5e-09 34.9 1.4 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like OEP PF02321.18 AMK79311.1 - 0.00026 20.8 17.4 0.00026 20.8 17.4 1.8 1 1 0 1 1 1 1 Outer membrane efflux protein Biotin_lipoyl PF00364.22 AMK79311.1 - 0.00082 19.2 0.1 0.064 13.1 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD PF00529.20 AMK79311.1 - 0.0012 18.7 1.0 0.0018 18.1 1.0 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Spc7 PF08317.11 AMK79311.1 - 0.0022 16.9 0.6 0.0032 16.4 0.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein PTS_EIIA_1 PF00358.20 AMK79311.1 - 0.087 12.6 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DUF641 PF04859.12 AMK79311.1 - 0.14 12.5 4.5 3.8 7.8 0.2 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.10 AMK79311.1 - 0.64 10.4 24.6 0.48 10.8 8.2 2.3 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ABC_tran PF00005.27 AMK79312.1 - 7.1e-56 188.5 0.0 3.3e-27 95.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 AMK79312.1 - 7.5e-40 137.1 3.8 9.9e-40 136.7 3.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AMK79312.1 - 3.1e-20 72.7 4.5 5.8e-20 71.7 4.6 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 AMK79312.1 - 9.9e-19 68.3 4.8 1.2e-05 25.3 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 AMK79312.1 - 5.5e-18 65.2 10.2 5.5e-18 65.2 10.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 AMK79312.1 - 4.6e-06 26.6 0.3 0.006 16.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 AMK79312.1 - 5.4e-06 26.4 0.0 0.082 12.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 AMK79312.1 - 3.3e-05 23.5 0.5 0.17 11.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 AMK79312.1 - 0.00047 20.2 0.3 0.072 13.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_4 PF12730.7 AMK79312.1 - 0.0008 19.4 10.7 0.0018 18.3 10.7 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein RNA_helicase PF00910.22 AMK79312.1 - 0.0017 18.7 0.1 0.57 10.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 AMK79312.1 - 0.0018 18.6 0.1 2.1 8.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AMK79312.1 - 0.0029 18.2 0.2 0.14 12.6 0.3 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AMK79312.1 - 0.0034 17.8 0.0 0.49 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 AMK79312.1 - 0.005 16.3 0.0 7.5 5.9 0.0 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain Ploopntkinase3 PF18751.1 AMK79312.1 - 0.018 15.0 0.6 0.39 10.6 0.1 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 AMK79312.1 - 0.056 13.4 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 AMK79312.1 - 0.085 12.6 0.0 15 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AMK79312.1 - 0.09 13.2 0.1 19 5.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AMK79312.1 - 0.098 13.2 0.1 1.9 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AMK79312.1 - 0.1 12.9 0.6 25 5.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 AMK79312.1 - 0.13 12.5 0.0 24 5.2 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 AMK79312.1 - 0.16 11.5 0.1 9.8 5.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 AMK79312.1 - 0.16 10.9 0.2 13 4.7 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 AMK79312.1 - 0.38 10.4 0.6 7.3 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 AMK79313.1 - 8.9e-32 110.5 18.6 1e-31 110.3 18.6 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AMK79313.1 - 4.3e-28 98.2 17.6 4.3e-28 98.2 17.6 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AMK79313.1 - 6.4e-16 58.5 19.8 1.1e-15 57.7 19.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AMK79313.1 - 2.7e-05 24.2 14.0 2.7e-05 24.2 14.0 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein DDE_Tnp_1 PF01609.21 AMK79314.1 - 4.7e-18 65.6 0.1 7.8e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain DUF4096 PF13340.6 AMK79314.1 - 4.2e-16 58.9 0.6 9.4e-16 57.8 0.6 1.6 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK79314.1 - 1.7e-12 47.5 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK79314.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 Transposase DDE domain BRI3BP PF14965.6 AMK79315.1 - 0.0091 15.5 0.0 0.01 15.4 0.0 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 PepSY_2 PF13670.6 AMK79315.1 - 0.011 15.7 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Fzo_mitofusin PF04799.13 AMK79315.1 - 0.066 12.8 0.7 0.076 12.6 0.7 1.1 1 0 0 1 1 1 0 fzo-like conserved region Conotoxin PF02950.17 AMK79315.1 - 0.26 12.3 2.2 0.73 10.9 2.2 1.7 1 1 0 1 1 1 0 Conotoxin DUF2703 PF10865.8 AMK79316.1 - 5.7e-36 123.3 0.1 6.5e-36 123.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2703) DUF4472 PF14739.6 AMK79317.1 - 0.0087 16.8 3.5 0.01 16.5 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) Fibrinogen_BP PF08017.11 AMK79317.1 - 0.02 13.3 0.1 0.02 13.3 0.1 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein E1-E2_ATPase PF00122.20 AMK79318.1 - 4.7e-49 166.4 0.7 4.7e-49 166.4 0.7 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 AMK79318.1 - 1.1e-43 150.0 0.1 2.5e-43 148.8 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AMK79318.1 - 6.7e-05 23.3 0.0 0.00023 21.6 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AMK79318.1 - 0.029 14.1 1.0 0.089 12.5 0.6 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PTS_EIIA_1 PF00358.20 AMK79318.1 - 0.05 13.4 0.0 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HTH_5 PF01022.20 AMK79319.1 - 1.1e-13 50.8 1.5 1.5e-13 50.4 0.4 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AMK79319.1 - 8.9e-08 32.1 0.7 1.3e-07 31.5 0.7 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 AMK79319.1 - 0.00016 21.4 0.4 0.0003 20.6 0.4 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AMK79319.1 - 0.00057 19.4 0.3 0.0013 18.2 0.3 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 AMK79319.1 - 0.0019 18.1 0.2 0.0033 17.4 0.2 1.5 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 AMK79319.1 - 0.014 15.2 1.1 0.036 13.9 0.2 2.2 3 1 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.6 AMK79319.1 - 0.024 14.6 0.5 0.039 14.0 0.5 1.4 1 0 0 1 1 1 0 Winged helix-turn helix PaaX PF07848.12 AMK79319.1 - 0.085 13.1 0.1 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 PaaX-like protein MarR PF01047.22 AMK79319.1 - 0.1 12.5 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 AMK79319.1 - 0.24 11.3 2.2 0.25 11.2 0.4 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain V4R PF02830.18 AMK79320.1 - 2.7e-11 43.3 1.3 5e-11 42.5 0.5 1.9 2 0 0 2 2 2 1 V4R domain Thioredoxin_2 PF13098.6 AMK79321.1 - 0.0037 17.7 0.0 0.007 16.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF4174 PF13778.6 AMK79321.1 - 0.0072 16.8 0.0 0.0095 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) 2-ph_phosp PF04029.14 AMK79321.1 - 0.04 13.1 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase Thioredoxin_8 PF13905.6 AMK79321.1 - 0.098 13.0 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like SLC3A2_N PF16028.5 AMK79321.1 - 0.13 11.8 0.1 2.5 7.7 0.1 2.1 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Thioredoxin PF00085.20 AMK79321.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DsbD PF02683.15 AMK79322.1 - 5e-26 91.9 13.8 6.5e-26 91.5 13.8 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AMK79322.1 - 5.1e-09 36.4 31.2 2.8e-08 34.0 22.7 2.5 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF2157 PF09925.9 AMK79322.1 - 0.065 13.0 11.0 0.025 14.4 7.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) ACR_tran PF00873.19 AMK79323.1 - 0 1167.8 16.3 0 1167.7 16.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 AMK79323.1 - 0.85 8.5 34.6 0.06 12.3 0.8 3.2 3 0 0 3 3 3 0 MMPL family UPF0060 PF02694.15 AMK79324.1 - 2.5e-40 137.0 8.8 2.9e-40 136.8 8.8 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 AMK79324.1 - 0.062 13.5 9.3 0.17 12.1 9.3 1.7 1 1 0 1 1 1 0 EamA-like transporter family HlyD_D23 PF16576.5 AMK79325.1 - 1.6e-45 154.9 3.7 8.4e-45 152.6 3.7 1.9 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 AMK79325.1 - 1.7e-20 73.7 7.0 1e-17 64.7 0.1 3.7 4 1 0 4 4 4 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AMK79325.1 - 1.6e-08 34.2 3.0 5.1e-06 26.2 0.3 3.5 4 0 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 AMK79325.1 - 3.9e-06 26.6 0.4 0.041 13.7 0.1 3.4 3 0 0 3 3 3 2 Biotin-requiring enzyme HlyD PF00529.20 AMK79325.1 - 0.00096 19.0 2.0 0.03 14.2 2.0 2.7 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Peptidase_M23 PF01551.22 AMK79325.1 - 0.0018 18.4 2.0 0.16 12.2 0.0 3.6 3 1 1 4 4 4 1 Peptidase family M23 PYNP_C PF07831.13 AMK79325.1 - 0.008 15.8 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.7 AMK79325.1 - 0.034 12.9 0.2 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein OEP PF02321.18 AMK79326.1 - 2e-50 171.2 17.3 4.4e-26 91.8 0.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein DUF4407 PF14362.6 AMK79326.1 - 0.0081 15.5 6.7 1.7 7.9 4.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) SF1-HH PF16275.5 AMK79326.1 - 0.017 15.4 0.2 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain DUF4404 PF14357.6 AMK79326.1 - 0.48 11.1 0.1 0.48 11.1 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) I_LWEQ PF01608.17 AMK79326.1 - 1.4 9.1 10.4 0.36 11.1 6.5 1.9 2 0 0 2 2 2 0 I/LWEQ domain TraL PF07178.11 AMK79328.1 - 2e-27 95.5 0.8 2.2e-27 95.3 0.8 1.0 1 0 0 1 1 1 1 TraL protein NCE101 PF11654.8 AMK79328.1 - 0.032 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Non-classical export protein 1 TraE PF05309.11 AMK79329.1 - 2.4e-28 98.7 0.0 2.8e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 TraE protein TraK PF06586.11 AMK79330.1 - 3.2e-20 72.8 0.4 4.2e-20 72.4 0.4 1.1 1 0 0 1 1 1 1 TraK protein TrbI PF03743.14 AMK79331.1 - 2.6e-34 118.7 0.0 4.7e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein Fmp27_WPPW PF10359.9 AMK79331.1 - 0.031 13.1 0.4 0.042 12.7 0.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Thioredoxin_2 PF13098.6 AMK79332.1 - 3.5e-11 43.5 0.0 7.6e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain DsbC_N PF10411.9 AMK79332.1 - 5.7e-06 25.7 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 AMK79332.1 - 5.2e-05 23.1 0.1 0.0086 15.9 0.1 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.6 AMK79332.1 - 0.0003 20.7 0.1 0.0016 18.3 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 AMK79332.1 - 0.009 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 AMK79332.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like zinc_ribbon_15 PF17032.5 AMK79332.1 - 0.069 13.9 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon family Redoxin PF08534.10 AMK79332.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_4 PF13462.6 AMK79332.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 AMK79332.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin TraV PF09676.10 AMK79333.1 - 5.7e-19 69.4 7.2 6e-15 56.4 2.4 2.3 1 1 1 2 2 2 2 Type IV conjugative transfer system lipoprotein (TraV) TrbC PF04956.13 AMK79334.1 - 6.5e-07 29.5 11.4 7.3e-07 29.3 11.4 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family DctM PF06808.12 AMK79334.1 - 0.00076 18.4 8.2 0.00076 18.4 8.2 1.3 1 1 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component RRXRR PF14239.6 AMK79335.1 - 2.5e-10 40.5 0.1 2.9e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 RRXRR protein TraC_F_IV PF11130.8 AMK79336.1 - 4e-49 167.4 0.2 7.7e-49 166.4 0.2 1.5 1 0 0 1 1 1 1 F pilus assembly Type-IV secretion system for plasmid transfer AAA_10 PF12846.7 AMK79336.1 - 3.3e-09 36.1 0.0 7.6e-09 34.9 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain TraG-D_C PF12696.7 AMK79336.1 - 0.059 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Peptidase_S26 PF10502.9 AMK79338.1 - 1.8e-13 50.5 0.0 2.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DRTGG PF07085.12 AMK79338.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 DRTGG domain Peptidase_S24 PF00717.23 AMK79338.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase S24-like TrbC_Ftype PF09673.10 AMK79339.1 - 7e-15 55.0 0.0 1.8e-13 50.5 0.0 2.4 2 1 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein YqhG PF11079.8 AMK79339.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function TraU PF06834.11 AMK79340.1 - 1.4e-97 326.7 0.3 1.9e-97 326.2 0.3 1.2 1 0 0 1 1 1 1 TraU protein TraN PF06986.11 AMK79341.1 - 4.1e-39 134.7 22.2 1.9e-23 83.4 1.0 2.5 2 0 0 2 2 2 2 Type-1V conjugative transfer system mating pair stabilisation Bac_DNA_binding PF00216.21 AMK79342.1 - 2.3e-32 111.0 0.0 2.6e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AMK79342.1 - 4.5e-07 30.0 0.0 4.7e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AMK79342.1 - 0.0039 17.0 0.0 0.0053 16.6 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AMK79342.1 - 0.028 14.6 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 AMK79342.1 - 0.038 14.2 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 hemP PF10636.9 AMK79344.1 - 2.5e-18 65.6 0.3 3.1e-18 65.3 0.3 1.1 1 0 0 1 1 1 1 Hemin uptake protein hemP HisKA_2 PF07568.12 AMK79346.1 - 0.02 15.0 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase TonB_dep_Rec PF00593.24 AMK79348.1 - 2.8e-40 139.6 35.4 9.9e-40 137.8 35.4 1.9 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 AMK79348.1 - 1.8e-22 80.0 0.9 1.8e-22 80.0 0.9 3.0 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain SPRY PF00622.28 AMK79348.1 - 0.05 13.7 0.4 0.37 10.9 0.2 2.3 2 0 0 2 2 2 0 SPRY domain CPSase_L_D2 PF02786.17 AMK79349.1 - 2.6e-09 36.9 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 AMK79349.1 - 4.1e-07 30.0 0.0 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 AMK79349.1 - 6.2e-06 25.9 0.0 2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 AMK79349.1 - 6.5e-06 26.2 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_3 PF02655.14 AMK79349.1 - 8e-06 26.0 0.0 0.00043 20.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_N PF18130.1 AMK79349.1 - 0.00011 22.7 0.1 0.00035 21.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp N-terminal domain ATP-grasp PF02222.22 AMK79349.1 - 0.00084 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 AMK79349.1 - 0.023 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 AMK79349.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RimK PF08443.11 AMK79349.1 - 0.044 13.4 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain IucA_IucC PF04183.12 AMK79350.1 - 1.7e-39 135.8 0.0 3.2e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 AMK79350.1 - 4e-18 66.3 0.5 1e-17 65.0 0.5 1.7 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter MFS_1 PF07690.16 AMK79351.1 - 4.9e-28 98.1 59.6 5.3e-20 71.6 38.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AMK79351.1 - 8.5e-06 24.9 0.0 2.3e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 MFS_1 like family IucA_IucC PF04183.12 AMK79352.1 - 1.4e-58 198.3 0.0 1.9e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 AMK79352.1 - 4e-37 128.1 2.3 4e-37 128.1 2.3 2.1 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter DUF4733 PF15878.5 AMK79352.1 - 0.038 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) Orn_Arg_deC_N PF02784.16 AMK79353.1 - 7.9e-37 126.9 0.0 9.7e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AMK79353.1 - 4.5e-13 49.3 0.0 4.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AMK79353.1 - 1.2e-11 44.7 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HpcH_HpaI PF03328.14 AMK79354.1 - 6.5e-34 117.0 0.0 7.8e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PepSY_TM PF03929.16 AMK79355.1 - 1.7e-26 93.5 2.6 2.2e-19 70.2 0.9 2.1 2 0 0 2 2 2 2 PepSY-associated TM region DUF1635 PF07795.11 AMK79355.1 - 0.38 10.6 2.9 0.55 10.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) ResIII PF04851.15 AMK79356.1 - 9.7e-34 116.8 0.0 1.7e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EcoEI_R_C PF08463.10 AMK79356.1 - 5.5e-24 85.2 0.0 1.1e-23 84.3 0.0 1.5 1 0 0 1 1 1 1 EcoEI R protein C-terminal SWI2_SNF2 PF18766.1 AMK79356.1 - 2.6e-15 56.7 0.0 7.6e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N_2 PF13588.6 AMK79356.1 - 6e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N PF04313.14 AMK79356.1 - 1.7e-06 28.1 0.0 0.00046 20.2 0.0 2.6 1 1 1 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) DEAD PF00270.29 AMK79356.1 - 0.0003 20.6 0.0 0.001 18.8 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AMK79356.1 - 0.0013 19.1 0.0 0.0036 17.6 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.6 AMK79356.1 - 0.033 14.0 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3659 PF12396.8 AMK79356.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) MDMPI_N PF11716.8 AMK79356.1 - 0.41 11.3 2.9 0.63 10.7 0.2 2.4 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain N6_Mtase PF02384.16 AMK79357.1 - 4.3e-62 210.2 0.0 5.9e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 AMK79357.1 - 4.7e-15 56.4 0.0 9.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 HsdM N-terminal domain UPF0020 PF01170.18 AMK79357.1 - 2.5e-08 33.8 0.0 5.1e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 MTS PF05175.14 AMK79357.1 - 0.027 14.0 0.0 0.73 9.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain YhcG_C PF06250.11 AMK79358.1 - 2.8e-56 189.6 0.0 4.4e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 YhcG PDDEXK nuclease domain DUF1016_N PF17761.1 AMK79358.1 - 4.8e-38 130.4 0.0 1.2e-37 129.1 0.0 1.6 1 1 0 1 1 1 1 DUF1016 N-terminal domain PDDEXK_1 PF12705.7 AMK79358.1 - 0.015 15.3 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Methylase_S PF01420.19 AMK79359.1 - 2.3e-11 44.2 0.0 1.1e-08 35.5 0.0 2.5 3 0 0 3 3 3 2 Type I restriction modification DNA specificity domain DUF1525 PF07511.11 AMK79359.1 - 0.0096 16.1 0.7 0.18 12.0 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1525) DUF840 PF05801.11 AMK79359.1 - 0.1 12.7 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) NOD2_WH PF17779.1 AMK79360.1 - 0.022 15.1 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 NOD2 winged helix domain HrpB1_HrpK PF09613.10 AMK79360.1 - 0.04 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Homeodomain PF00046.29 AMK79360.1 - 0.044 13.6 0.1 1.2 9.0 0.0 2.8 2 0 0 2 2 2 0 Homeodomain Sec34 PF04136.15 AMK79360.1 - 0.092 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Sec34-like family Nse5 PF08691.10 AMK79361.1 - 0.022 13.4 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 DUF1845 PF08900.11 AMK79361.1 - 0.084 12.6 0.4 0.13 12.0 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) SSB PF00436.25 AMK79362.1 - 1.1e-34 118.6 0.1 1.3e-34 118.4 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4960 PF16324.5 AMK79362.1 - 0.079 12.5 0.0 0.095 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4960) Transpeptidase PF00905.22 AMK79362.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain RecT PF03837.14 AMK79363.1 - 6.2e-16 58.5 0.3 1e-15 57.8 0.3 1.3 1 0 0 1 1 1 1 RecT family zf_UBZ PF18439.1 AMK79364.1 - 0.11 12.2 0.5 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger YqaJ PF09588.10 AMK79365.1 - 1e-22 80.9 0.0 1.6e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain AAA_5 PF07728.14 AMK79367.1 - 3.1e-20 72.6 0.0 4.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 AMK79367.1 - 7.8e-19 67.7 0.1 1.2e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA PF00004.29 AMK79367.1 - 5.7e-06 26.8 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AMK79367.1 - 3.4e-05 24.3 0.0 6.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AMK79367.1 - 0.0029 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AMK79367.1 - 0.0053 17.0 0.4 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 AMK79367.1 - 0.01 16.1 0.1 0.025 14.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 AMK79367.1 - 0.011 16.2 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AMK79367.1 - 0.014 14.8 0.0 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AMK79367.1 - 0.019 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_7 PF17867.1 AMK79367.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_29 PF13555.6 AMK79367.1 - 0.025 14.3 0.1 0.058 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 AMK79367.1 - 0.026 14.4 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 AMK79367.1 - 0.033 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AMK79367.1 - 0.041 13.5 0.2 0.097 12.2 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 AMK79367.1 - 0.043 14.3 0.1 0.075 13.6 0.1 1.3 1 0 0 1 1 1 0 ABC transporter AFG1_ATPase PF03969.16 AMK79367.1 - 0.063 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_23 PF13476.6 AMK79367.1 - 0.066 13.7 0.1 0.096 13.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AMK79367.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AMK79367.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 AMK79367.1 - 0.23 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_9 PF12781.7 AMK79367.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region DUF3150 PF11348.8 AMK79369.1 - 1.8e-92 309.2 0.0 2.1e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) CobT PF06213.12 AMK79370.1 - 8.9e-09 35.1 11.2 5.1e-08 32.6 11.2 2.1 1 1 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA PF00092.28 AMK79370.1 - 1.1e-08 35.5 0.0 3.6e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.8 AMK79370.1 - 2.4e-05 24.1 0.0 0.048 13.3 0.0 3.1 2 1 0 2 2 2 2 Cobalamin biosynthesis protein CobT VWA domain SOG2 PF10428.9 AMK79370.1 - 0.12 11.6 5.3 0.2 10.8 5.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 AMK79370.1 - 0.53 10.1 11.0 0.71 9.7 11.0 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 AMK79370.1 - 0.88 8.1 6.6 1.2 7.6 6.6 1.1 1 0 0 1 1 1 0 Macoilin family zinc-ribbons_6 PF07191.12 AMK79373.1 - 0.069 13.1 5.2 0.19 11.8 5.2 1.7 1 1 0 1 1 1 0 zinc-ribbons AhpC-TSA PF00578.21 AMK79373.1 - 0.29 11.1 5.1 7.5 6.5 0.0 3.1 2 1 1 3 3 3 0 AhpC/TSA family DUF4942 PF13708.6 AMK79375.1 - 1.1e-47 162.6 0.0 1.8e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4942) DUF4034 PF13226.6 AMK79375.1 - 0.036 13.4 0.3 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) HATPase_c_3 PF13589.6 AMK79376.1 - 1.9e-06 27.7 0.0 3.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FlhD PF05247.13 AMK79379.1 - 1.8e-07 31.3 0.0 2.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DDE_3 PF13358.6 AMK79379.1 - 0.04 13.7 0.0 0.94 9.2 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease FlhC PF05280.11 AMK79380.1 - 8.7e-26 90.7 0.2 1.2e-25 90.3 0.2 1.2 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) DUF4325 PF14213.6 AMK79381.1 - 1.5e-09 37.4 0.1 3.6e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 STAS-like domain of unknown function (DUF4325) FlhD PF05247.13 AMK79381.1 - 0.002 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF713 PF05218.14 AMK79381.1 - 0.044 13.5 0.2 0.065 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) FlhC PF05280.11 AMK79382.1 - 1.2e-17 64.1 0.2 1.5e-17 63.9 0.2 1.0 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) RecR PF02132.15 AMK79382.1 - 0.027 14.0 2.3 0.07 12.7 2.3 1.7 1 1 0 1 1 1 0 RecR protein Phage_ABA_S PF18066.1 AMK79382.1 - 0.05 14.3 0.0 0.075 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage ABA sandwich domain Phage_integrase PF00589.22 AMK79383.1 - 8.7e-32 110.3 0.1 2e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AMK79383.1 - 0.00045 20.5 0.1 0.0018 18.6 0.1 2.0 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AMK79383.1 - 0.0049 17.2 0.1 0.0097 16.2 0.1 1.5 1 0 0 1 1 1 1 Phage integrase SAM-like domain CRIC_ras_sig PF10534.9 AMK79383.1 - 0.059 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras MerR_1 PF13411.6 AMK79384.1 - 8.2e-22 77.1 0.1 1.4e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AMK79384.1 - 2.2e-09 36.9 0.0 4.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein Bac_DNA_binding PF00216.21 AMK79385.1 - 4.5e-31 106.9 0.6 5e-31 106.8 0.6 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 AMK79385.1 - 1.1e-05 25.6 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 AMK79385.1 - 3e-05 23.8 0.1 3.8e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 AMK79385.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 AMK79385.1 - 0.035 14.2 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 B3_4 PF03483.17 AMK79386.1 - 3.2e-67 225.5 0.0 6.2e-67 224.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 AMK79386.1 - 2.3e-52 177.5 0.0 4.8e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AMK79386.1 - 1.9e-27 95.5 0.1 4e-27 94.5 0.1 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AMK79386.1 - 2.2e-24 85.4 0.1 5.6e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 AMK79386.1 - 8.6e-17 61.2 0.1 4e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 AMK79387.1 - 3.5e-104 347.6 0.0 4.3e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AMK79387.1 - 6.8e-26 90.0 0.9 1.4e-25 89.0 0.9 1.5 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 AMK79387.1 - 0.00032 20.2 0.0 0.0016 17.9 0.0 2.0 2 1 1 3 3 3 1 Phenylalanyl tRNA synthetase beta chain CLM domain ACT PF01842.25 AMK79387.1 - 0.019 14.7 0.1 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 ACT domain YopD PF05844.12 AMK79387.1 - 0.07 12.1 0.1 0.098 11.7 0.1 1.1 1 0 0 1 1 1 0 YopD protein Ribosomal_L20 PF00453.18 AMK79388.1 - 3.5e-49 165.3 8.0 4.1e-49 165.1 8.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_L35p PF01632.19 AMK79389.1 - 2.4e-24 85.6 9.4 2.6e-24 85.5 9.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Asr PF06392.11 AMK79389.1 - 0.1 13.0 4.9 0.2 12.1 4.9 1.5 1 0 0 1 1 1 0 Acid shock protein repeat IF3_C PF00707.22 AMK79390.1 - 4.4e-36 122.7 1.5 6.4e-36 122.2 1.5 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AMK79390.1 - 1.4e-26 92.6 0.0 3.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain HTH_52 PF18576.1 AMK79390.1 - 0.024 14.8 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain tRNA-synt_2b PF00587.25 AMK79391.1 - 1.6e-44 152.1 0.0 6.2e-44 150.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AMK79391.1 - 4.1e-22 78.1 0.5 1.1e-21 76.8 0.5 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 AMK79391.1 - 7.8e-17 61.1 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 AMK79391.1 - 2.2e-13 50.0 0.0 7.3e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 TGS domain SOG2 PF10428.9 AMK79392.1 - 0.015 14.6 8.8 0.018 14.3 8.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 AMK79392.1 - 0.13 10.9 4.1 0.14 10.8 4.1 1.1 1 0 0 1 1 1 0 Hamartin protein NUDE_C PF04880.13 AMK79392.1 - 0.31 11.5 6.5 0.49 10.8 6.5 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SSFA2_C PF14723.6 AMK79392.1 - 0.55 10.1 7.1 0.18 11.7 2.8 2.0 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus Mucin PF01456.17 AMK79392.1 - 0.62 10.1 31.3 1.5 8.8 31.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 AMK79392.1 - 3.1 5.8 13.4 3.9 5.5 13.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1631 PF07793.11 AMK79392.1 - 4.6 5.5 10.4 6.3 5.1 10.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) ORC6 PF05460.13 AMK79392.1 - 5.3 6.2 9.8 5.2 6.2 6.3 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Coprogen_oxidas PF01218.18 AMK79393.1 - 3.3e-133 443.0 0.0 3.7e-133 442.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ProQ PF04352.13 AMK79394.1 - 1.4e-33 115.1 0.1 1.4e-33 115.1 0.1 1.7 2 0 0 2 2 2 1 ProQ/FINO family Gcw_chp PF09694.10 AMK79396.1 - 8.4e-16 58.6 3.7 9.6e-16 58.5 3.7 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) Porin_4 PF13609.6 AMK79396.1 - 0.011 15.5 1.5 0.012 15.4 1.5 1.2 1 0 0 1 1 1 0 Gram-negative porin Sigma70_r4_2 PF08281.12 AMK79397.1 - 5.9e-18 64.3 0.0 9.5e-18 63.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AMK79397.1 - 9.1e-15 53.9 0.0 1.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AMK79397.1 - 8.6e-13 48.6 0.0 1.7e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r2 PF04542.14 AMK79397.1 - 7.7e-12 44.8 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 GerE PF00196.19 AMK79397.1 - 2.1e-05 24.0 0.0 3.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 AMK79397.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AMK79397.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.6 AMK79397.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-HC2 PF13490.6 AMK79398.1 - 0.00057 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger Peptidase_S8 PF00082.22 AMK79399.1 - 2.5e-35 122.2 0.6 1.5e-34 119.6 0.6 2.0 1 1 0 1 1 1 1 Subtilase family Glyco_tran_28_C PF04101.16 AMK79400.1 - 7.6e-09 35.8 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Alginate_exp PF13372.6 AMK79401.1 - 3.7e-32 111.6 12.2 7.1e-32 110.6 12.2 1.4 1 1 0 1 1 1 1 Alginate export DUF2334 PF10096.9 AMK79402.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_tran_28_C PF04101.16 AMK79403.1 - 6.8e-12 45.7 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ABC_membrane PF00664.23 AMK79404.1 - 2.4e-50 171.7 5.8 3.2e-50 171.3 5.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AMK79404.1 - 5.4e-38 130.6 0.0 9.4e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AMK79404.1 - 1.1e-06 28.7 0.1 0.0029 17.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AMK79404.1 - 5.5e-05 22.7 0.0 0.0003 20.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 AMK79404.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 AMK79404.1 - 0.0099 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 AMK79404.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 AMK79404.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AMK79404.1 - 0.018 15.3 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AMK79404.1 - 0.021 15.2 0.3 0.066 13.6 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 AMK79404.1 - 0.065 13.1 0.3 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 AMK79404.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AMK79404.1 - 0.069 12.9 0.1 0.26 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AMK79404.1 - 0.074 13.6 0.0 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AMK79404.1 - 0.077 13.2 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain CoA_binding_3 PF13727.6 AMK79404.1 - 0.085 12.9 0.4 0.29 11.1 0.4 1.9 1 0 0 1 1 1 0 CoA-binding domain DUF87 PF01935.17 AMK79404.1 - 0.094 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain APS_kinase PF01583.20 AMK79404.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 AMK79404.1 - 0.13 11.9 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SLATT_1 PF18181.1 AMK79404.1 - 0.14 12.1 0.1 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 ATP1G1_PLM_MAT8 PF02038.16 AMK79404.1 - 2.2 7.8 4.9 0.63 9.5 0.1 2.5 3 0 0 3 3 2 0 ATP1G1/PLM/MAT8 family APH PF01636.23 AMK79405.1 - 9.6e-13 48.6 7.1 9.6e-13 48.6 7.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 AMK79405.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase His_Phos_1 PF00300.22 AMK79406.1 - 1.3e-45 155.4 0.4 1.6e-45 155.2 0.4 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThrE_2 PF12821.7 AMK79406.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE APH PF01636.23 AMK79407.1 - 2e-13 50.8 2.3 2e-13 50.8 2.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Hepar_II_III_N PF16889.5 AMK79408.1 - 4.3e-49 167.6 0.0 6.1e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Heparinase II/III N-terminus Hepar_II_III PF07940.13 AMK79408.1 - 9.4e-42 143.3 0.1 1.4e-41 142.7 0.1 1.2 1 0 0 1 1 1 1 Heparinase II/III-like protein Alginate_lyase PF05426.12 AMK79408.1 - 0.00031 20.4 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 Alginate lyase Hepar_II_III_N PF16889.5 AMK79409.1 - 2.3e-45 155.4 0.0 3.5e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Heparinase II/III N-terminus Hepar_II_III PF07940.13 AMK79409.1 - 4.2e-40 137.9 0.0 6.3e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Heparinase II/III-like protein Glycos_transf_1 PF00534.20 AMK79410.1 - 5.4e-38 130.2 0.0 9.4e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AMK79410.1 - 1.5e-32 112.9 0.1 3e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 AMK79410.1 - 6.8e-11 42.4 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AMK79410.1 - 0.00065 19.7 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_tran_28_C PF04101.16 AMK79411.1 - 9.9e-13 48.4 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF4917 PF16263.5 AMK79411.1 - 0.073 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) PALP PF00291.25 AMK79413.1 - 3.3e-63 213.8 0.4 3.7e-63 213.7 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIB PF00382.19 AMK79413.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF2188 PF09954.9 AMK79413.1 - 0.81 9.9 0.0 0.81 9.9 0.0 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF485 PF04341.12 AMK79414.1 - 5.4 7.1 9.3 7.5 6.6 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Sre PF03125.18 AMK79414.1 - 7 5.7 8.3 9 5.3 8.3 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Rhomboid PF01694.22 AMK79415.1 - 4.8e-38 130.5 14.5 4.8e-38 130.5 14.5 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3418 PF11898.8 AMK79416.1 - 5e-186 619.8 0.4 5e-186 619.8 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3418) HA2 PF04408.23 AMK79416.1 - 5.1e-16 58.9 0.1 1.2e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 AMK79416.1 - 1.2e-13 51.2 0.0 3.2e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 AMK79416.1 - 2.5e-12 47.1 0.1 8e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 AMK79416.1 - 4.5e-05 23.3 0.2 0.00059 19.6 0.1 2.8 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AMK79416.1 - 0.00024 21.5 0.1 0.00073 19.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 AMK79416.1 - 0.00081 19.7 0.4 0.0043 17.3 0.1 2.4 2 1 0 2 2 1 1 AAA domain Ribosomal_S30AE PF02482.19 AMK79416.1 - 0.0009 20.0 1.0 1.3 9.8 0.2 2.9 2 0 0 2 2 2 2 Sigma 54 modulation protein / S30EA ribosomal protein T2SSE PF00437.20 AMK79416.1 - 0.0026 16.8 0.0 0.0065 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 AMK79416.1 - 0.0033 17.0 0.0 0.24 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 AMK79416.1 - 0.015 15.2 0.0 0.069 13.1 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AMK79416.1 - 0.019 14.7 0.2 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AMK79416.1 - 0.033 14.7 0.0 0.091 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 AMK79416.1 - 0.044 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AMK79416.1 - 0.046 13.6 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 1 0 NACHT domain ResIII PF04851.15 AMK79416.1 - 0.13 12.3 0.0 12 5.9 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 AMK79416.1 - 0.14 11.6 0.0 0.47 9.9 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein KinB_sensor PF16767.5 AMK79416.1 - 3.9 8.0 9.7 4.1 7.9 0.1 3.5 3 1 1 4 4 4 0 Sensor domain of alginate biosynthesis sensor protein KinB DDE_Tnp_1 PF01609.21 AMK79417.1 - 1.8e-17 63.7 0.2 2.4e-16 60.0 0.2 2.4 1 1 0 1 1 1 1 Transposase DDE domain DUF772 PF05598.11 AMK79417.1 - 3.7e-17 62.1 0.1 8.2e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 AMK79417.1 - 4.5e-14 52.7 3.9 1.1e-13 51.4 0.2 2.5 2 0 0 2 2 2 1 Transposase DDE domain FlxA PF14282.6 AMK79417.1 - 0.0017 18.3 4.9 0.0052 16.8 4.9 1.8 1 0 0 1 1 1 1 FlxA-like protein FAP206 PF12018.8 AMK79417.1 - 0.0092 15.5 3.1 0.054 13.0 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function Fmp27_WPPW PF10359.9 AMK79417.1 - 0.017 14.0 4.3 0.024 13.5 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HrpA_pilin PF09589.10 AMK79417.1 - 0.025 15.3 4.0 0.17 12.6 2.7 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein DUF5082 PF16888.5 AMK79417.1 - 0.12 12.7 3.8 0.2 11.9 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF501 PF04417.12 AMK79417.1 - 0.19 11.5 1.2 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) NPV_P10 PF05531.12 AMK79417.1 - 0.71 10.4 2.7 1.7 9.2 1.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 AMK79417.1 - 0.77 10.1 6.3 0.21 11.9 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 AMK79417.1 - 4.5 7.7 9.7 1.2 9.5 2.6 3.2 3 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 AMK79417.1 - 9.3 6.6 11.2 2.1e+02 2.3 11.2 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain DDE_Tnp_1_2 PF13586.6 AMK79418.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK79418.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK79418.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK79418.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 AMK79419.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_5 PF01022.20 AMK79419.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 AMK79419.1 - 0.00036 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 AMK79419.1 - 0.0018 18.0 1.3 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 AMK79419.1 - 0.0055 16.2 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.12 AMK79419.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 AMK79419.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 AMK79419.1 - 0.037 13.8 0.1 0.89 9.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 AMK79419.1 - 0.038 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 AMK79419.1 - 0.044 13.8 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix GntR PF00392.21 AMK79419.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 AMK79419.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 AMK79419.1 - 0.12 12.5 0.0 0.81 9.9 0.0 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 AMK79419.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain IstB_IS21 PF01695.17 AMK79420.1 - 4.8e-56 189.3 0.0 6.3e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 AMK79420.1 - 2e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.16 AMK79420.1 - 4.1e-06 26.4 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 AMK79420.1 - 0.0021 18.5 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 AMK79420.1 - 0.0068 15.3 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase AAA_30 PF13604.6 AMK79420.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 AMK79420.1 - 0.031 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 AMK79420.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 AMK79420.1 - 0.031 14.5 0.5 0.28 11.5 0.3 2.1 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 AMK79420.1 - 0.031 13.3 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 AMK79420.1 - 0.044 13.5 0.2 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.14 AMK79420.1 - 0.05 13.5 1.6 0.87 9.5 0.0 2.5 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 AMK79420.1 - 0.054 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 AMK79420.1 - 0.096 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AMK79420.1 - 0.11 12.9 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 AMK79420.1 - 0.12 12.1 0.3 0.33 10.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AMK79420.1 - 0.13 12.6 2.0 0.25 11.6 1.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 AMK79420.1 - 0.17 11.9 0.3 0.47 10.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 AMK79420.1 - 0.32 11.0 1.2 0.73 9.8 0.6 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LysR_substrate PF03466.20 AMK79422.1 - 6.8e-40 136.7 0.0 8.9e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 AMK79422.1 - 1.4e-17 63.4 2.4 6.2e-17 61.3 2.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 AMK79422.1 - 0.059 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain adh_short_C2 PF13561.6 AMK79423.1 - 2.2e-59 200.8 0.4 2.5e-59 200.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AMK79423.1 - 1e-54 185.0 0.5 1.2e-54 184.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AMK79423.1 - 1.6e-18 67.2 1.0 2.1e-18 66.8 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 AMK79423.1 - 2.3e-06 27.2 1.9 1.5e-05 24.6 1.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AMK79423.1 - 0.00014 21.0 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 AMK79423.1 - 0.00072 18.8 0.2 0.0015 17.7 0.2 1.4 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 AMK79423.1 - 0.0012 18.3 0.4 0.0025 17.3 0.3 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 AMK79423.1 - 0.0021 18.0 0.5 0.0025 17.7 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Peripla_BP_6 PF13458.6 AMK79423.1 - 0.033 13.8 0.6 0.044 13.4 0.6 1.2 1 0 0 1 1 1 0 Periplasmic binding protein NmrA PF05368.13 AMK79423.1 - 0.16 11.5 0.9 0.25 10.9 0.8 1.4 1 1 0 1 1 1 0 NmrA-like family DUF4096 PF13340.6 AMK79424.1 - 3.6e-24 84.8 4.8 7.4e-24 83.8 4.8 1.5 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 AMK79425.1 - 4.1e-14 52.7 0.2 5e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 AMK79425.1 - 4.3e-13 49.4 2.6 1.7e-11 44.2 2.6 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 AMK79425.1 - 7.3e-07 29.3 0.0 9.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 AMK79425.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Oxidored_FMN PF00724.20 AMK79426.1 - 2.6e-08 33.5 0.0 2.7e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CbtA PF09490.10 AMK79427.1 - 7e-55 186.4 13.4 8e-55 186.3 13.4 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) VKOR PF07884.14 AMK79427.1 - 0.29 11.3 4.7 0.072 13.3 1.0 2.0 2 1 0 2 2 2 0 Vitamin K epoxide reductase family GATase_3 PF07685.14 AMK79428.1 - 5.1e-21 75.2 0.0 6.2e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AMK79428.1 - 0.049 13.7 0.5 0.077 13.0 0.5 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TP_methylase PF00590.20 AMK79429.1 - 1.1e-44 152.9 0.4 1.3e-44 152.7 0.4 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CbiC PF02570.15 AMK79430.1 - 5.8e-74 248.0 0.3 6.7e-74 247.8 0.3 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase CbiG_C PF01890.16 AMK79431.1 - 1.6e-36 125.4 0.0 1.8e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin synthesis G C-terminus # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylomonas_denitrificans-ASM78570v2/GCA_000785705.2_ASM78570v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylomonas_denitrificans-ASM78570v2/GCA_000785705.2_ASM78570v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylomonas_denitrificans-ASM78570v2/GCA_000785705.2_ASM78570v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Methylomonas_denitrificans-ASM78570v2/GCA_000785705.2_ASM78570v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:18:25 2019 # [ok]